PMC:3586680 / 17677-18672 JSONTXT 24 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T10069 0-7 IN denotes Whether
T10070 8-12 NN denotes WWOX
T10071 13-20 VB denotes affects
T10072 21-24 NN denotes TMZ
T10073 25-36 NN denotes sensitivity
T10074 37-40 VB denotes has
T10075 41-46 RB denotes never
T10076 47-51 VB denotes been
T10077 52-62 VB denotes determined
T10078 64-71 NN denotes Binding
T10079 72-80 NN denotes proteins
T10080 81-84 IN denotes for
T10081 85-89 NN denotes WWOX
T10082 90-96 CC denotes and/or
T10083 97-100 NN denotes p53
T10084 101-104 VB denotes are
T10085 105-111 JJ denotes likely
T10086 112-114 TO denotes to
T10087 115-121 VB denotes affect
T10088 122-131 NN denotes apoptosis
T10089 132-135 CC denotes and
T10090 136-139 NN denotes TMZ
T10091 140-151 NN denotes sensitivity
T10092 152-154 IN denotes in
T10093 155-158 NN denotes GBM
T10094 159-164 NN denotes cells
T10095 166-170 NN denotes WWOX
T10096 171-176 VB denotes binds
T10097 177-180 NN denotes MEK
T10098 180-181 -COMMA- denotes ,
T10099 182-185 CC denotes and
T10100 186-190 IN denotes that
T10101 191-194 NN denotes PMA
T10102 195-206 VB denotes dissociates
T10103 207-211 DT denotes this
T10104 212-219 NN denotes complex
T10105 220-223 IN denotes for
T10106 224-231 VB denotes causing
T10107 232-241 NN denotes apoptosis
T10108 242-244 IN denotes of
T10109 245-246 NN denotes T
T10110 247-255 NN denotes leukemia
T10111 256-261 NN denotes cells
T10112 262-263 -LRB- denotes (
T10113 263-266 NNP denotes Lin
T10114 267-269 FW denotes et
T10115 270-273 FW denotes al.
T10116 273-274 -COMMA- denotes ,
T10117 275-279 CD denotes 2011
T10118 279-280 -RRB- denotes )
T10119 282-286 RB denotes Thus
T10120 286-287 -COMMA- denotes ,
T10121 288-299 JJ denotes appropriate
T10122 300-309 NN denotes chemicals
T10123 309-310 -COMMA- denotes ,
T10124 311-316 WDT denotes which
T10125 317-322 VB denotes break
T10126 323-328 RP denotes apart
T10127 329-332 DT denotes the
T10128 333-341 NN denotes WWOX/MEK
T10129 342-349 NN denotes complex
T10130 349-350 -COMMA- denotes ,
T10131 351-354 VB denotes are
T10132 355-363 VB denotes expected
T10133 364-366 TO denotes to
T10134 367-372 VB denotes cause
T10135 373-376 NN denotes GBM
T10136 377-381 NN denotes cell
T10137 382-387 NN denotes death
T10138 389-400 JJ denotes Preliminary
T10139 401-408 NN denotes studies
T10140 409-413 IN denotes from
T10141 414-417 PRP-DOLLAR- denotes our
T10142 418-427 NN denotes screening
T10143 428-430 IN denotes of
T10144 431-440 NN denotes chemicals
T10145 441-445 VB denotes have
T10146 446-454 VB denotes selected
T10147 455-462 JJ denotes certain
T10148 463-468 JJ denotes small
T10149 469-478 NN denotes molecules
T10150 479-483 WDT denotes that
T10151 484-490 VB denotes induce
T10152 491-500 NN denotes apoptosis
T10153 501-503 IN denotes of
T10154 504-508 JJ denotes many
T10155 509-514 NN denotes types
T10156 515-517 IN denotes of
T10157 518-524 NN denotes cancer
T10158 525-530 NN denotes cells
T10159 531-532 -LRB- denotes (
T10160 532-534 FW denotes Lu
T10161 535-537 FW denotes et
T10162 538-541 FW denotes al.
T10163 541-542 -COMMA- denotes ,
T10164 543-554 JJ denotes unpublished
T10165 554-555 -RRB- denotes )
T10166 557-563 RB denotes Indeed
T10167 563-564 -COMMA- denotes ,
T10168 565-573 JJ denotes specific
T10169 574-584 NN denotes inhibition
T10170 585-587 IN denotes of
T10171 588-591 NN denotes MEK
T10172 592-594 IN denotes by
T10173 595-606 NN denotes selumetinib
T10174 607-615 VB denotes enhances
T10175 616-627 JJ denotes TMZ-induced
T10176 628-634 NN denotes cancer
T10177 635-639 NN denotes cell
T10178 640-645 NN denotes death
T10179 646-648 FW denotes in
T10180 649-653 FW denotes vivo
T10181 654-655 -LRB- denotes (
T10182 655-659 NNP denotes Holt
T10183 660-662 FW denotes et
T10184 663-666 FW denotes al.
T10185 666-667 -COMMA- denotes ,
T10186 668-672 CD denotes 2012
T10187 672-673 -RRB- denotes )
T10188 675-680 NN denotes Serum
T10189 681-688 NN denotes factors
T10190 689-692 MD denotes can
T10191 693-695 VB denotes be
T10192 696-704 VB denotes utilized
T10193 705-708 IN denotes for
T10194 709-717 VB denotes blocking
T10195 718-724 NN denotes cancer
T10196 725-731 NN denotes growth
T10197 733-736 IN denotes For
T10198 737-744 NN denotes example
T10199 744-745 -COMMA- denotes ,
T10200 746-751 NN denotes serum
T10201 752-762 NN denotes complement
T10202 763-766 NN denotes C1q
T10203 767-774 VB denotes induces
T10204 775-784 NN denotes apoptosis
T10205 785-787 IN denotes of
T10206 788-796 NN denotes prostate
T10207 797-803 NN denotes cancer
T10208 804-807 CC denotes and
T10209 808-822 NN denotes neuroblastomas
T10210 823-828 NN denotes cells
T10211 829-836 IN denotes without
T10212 837-850 NN denotes participation
T10213 851-853 IN denotes of
T10214 854-864 JJ denotes downstream
T10215 865-873 NN denotes proteins
T10216 874-876 IN denotes in
T10217 877-880 DT denotes the
T10218 881-890 JJ denotes classical
T10219 891-901 NN denotes activation
T10220 902-909 NN denotes pathway
T10221 910-911 -LRB- denotes (
T10222 911-915 NNP denotes Hong
T10223 916-918 FW denotes et
T10224 919-922 FW denotes al.
T10225 922-923 -COMMA- denotes ,
T10226 924-928 CD denotes 2009
T10227 928-929 -RRB- denotes )
T10228 931-933 IN denotes In
T10229 934-938 DT denotes this
T10230 939-944 NN denotes event
T10231 944-945 -COMMA- denotes ,
T10232 946-953 JJ denotes ectopic
T10233 954-958 NN denotes WWOX
T10234 959-961 VB denotes is
T10235 962-971 VB denotes activated
T10236 972-975 IN denotes for
T10237 976-984 VB denotes inducing
T10238 985-994 NN denotes apoptosis
R6669 T10070 T10071 arg1Of WWOX,affects
R6670 T10071 T10069 arg1Of affects,Whether
R6671 T10071 T10074 arg1Of affects,has
R6672 T10071 T10076 arg1Of affects,been
R6673 T10071 T10077 arg2Of affects,determined
R6674 T10073 T10071 arg2Of sensitivity,affects
R6675 T10073 T10072 arg1Of sensitivity,TMZ
R6676 T10077 T10074 arg2Of determined,has
R6677 T10077 T10075 arg1Of determined,never
R6678 T10077 T10076 arg2Of determined,been
R6679 T10079 T10078 arg1Of proteins,Binding
R6680 T10079 T10080 arg1Of proteins,for
R6681 T10079 T10084 arg1Of proteins,are
R6682 T10079 T10085 arg1Of proteins,likely
R6683 T10081 T10082 arg1Of WWOX,and/or
R6684 T10082 T10080 arg2Of and/or,for
R6685 T10083 T10082 arg2Of p53,and/or
R6686 T10085 T10084 arg2Of likely,are
R6687 T10087 T10085 arg2Of affect,likely
R6688 T10087 T10086 arg1Of affect,to
R6689 T10088 T10089 arg1Of apoptosis,and
R6690 T10089 T10087 arg2Of and,affect
R6691 T10089 T10092 arg1Of and,in
R6692 T10091 T10089 arg2Of sensitivity,and
R6693 T10091 T10090 arg1Of sensitivity,TMZ
R6694 T10094 T10092 arg2Of cells,in
R6695 T10094 T10093 arg1Of cells,GBM
R6696 T10095 T10096 arg1Of WWOX,binds
R6697 T10096 T10099 arg1Of binds,and
R6698 T10097 T10096 arg2Of MEK,binds
R6699 T10099 T10098 arg1Of and,","
R6700 T10101 T10102 arg1Of PMA,dissociates
R6701 T10102 T10099 arg2Of dissociates,and
R6702 T10102 T10100 arg1Of dissociates,that
R6703 T10104 T10102 arg2Of complex,dissociates
R6704 T10104 T10103 arg1Of complex,this
R6705 T10104 T10105 arg1Of complex,for
R6706 T10106 T10105 arg2Of causing,for
R6707 T10106 T10112 arg1Of causing,(
R6708 T10107 T10106 arg2Of apoptosis,causing
R6709 T10107 T10108 arg1Of apoptosis,of
R6710 T10111 T10108 arg2Of cells,of
R6711 T10111 T10109 arg1Of cells,T
R6712 T10111 T10110 arg1Of cells,leukemia
R6713 T10113 T10112 arg2Of Lin,(
R6714 T10113 T10114 arg1Of Lin,et
R6715 T10113 T10115 arg1Of Lin,al.
R6716 T10113 T10116 arg1Of Lin,","
R6717 T10117 T10116 arg2Of 2011,","
R6718 T10118 T10112 arg3Of ),(
R6719 T10122 T10121 arg1Of chemicals,appropriate
R6720 T10122 T10123 arg1Of chemicals,","
R6721 T10122 T10124 arg1Of chemicals,which
R6722 T10122 T10125 arg1Of chemicals,break
R6723 T10122 T10131 arg1Of chemicals,are
R6724 T10122 T10132 arg2Of chemicals,expected
R6725 T10122 T10134 arg1Of chemicals,cause
R6726 T10125 T10126 arg1Of break,apart
R6727 T10129 T10125 arg2Of complex,break
R6728 T10129 T10127 arg1Of complex,the
R6729 T10129 T10128 arg1Of complex,WWOX/MEK
R6730 T10132 T10119 arg1Of expected,Thus
R6731 T10132 T10120 arg1Of expected,","
R6732 T10132 T10130 arg1Of expected,","
R6733 T10132 T10131 arg2Of expected,are
R6734 T10134 T10132 arg3Of cause,expected
R6735 T10134 T10133 arg1Of cause,to
R6736 T10137 T10134 arg2Of death,cause
R6737 T10137 T10135 arg1Of death,GBM
R6738 T10137 T10136 arg1Of death,cell
R6739 T10139 T10138 arg1Of studies,Preliminary
R6740 T10139 T10140 arg1Of studies,from
R6741 T10139 T10145 arg1Of studies,have
R6742 T10139 T10146 arg1Of studies,selected
R6743 T10142 T10140 arg2Of screening,from
R6744 T10142 T10141 arg1Of screening,our
R6745 T10142 T10143 arg1Of screening,of
R6746 T10144 T10143 arg2Of chemicals,of
R6747 T10146 T10145 arg2Of selected,have
R6748 T10149 T10146 arg2Of molecules,selected
R6749 T10149 T10147 arg1Of molecules,certain
R6750 T10149 T10148 arg1Of molecules,small
R6751 T10149 T10150 arg1Of molecules,that
R6752 T10149 T10151 arg1Of molecules,induce
R6753 T10152 T10151 arg2Of apoptosis,induce
R6754 T10152 T10153 arg1Of apoptosis,of
R6755 T10155 T10153 arg2Of types,of
R6756 T10155 T10154 arg1Of types,many
R6757 T10155 T10156 arg1Of types,of
R6758 T10155 T10159 arg1Of types,(
R6759 T10158 T10156 arg2Of cells,of
R6760 T10158 T10157 arg1Of cells,cancer
R6761 T10162 T10159 arg2Of al.,(
R6762 T10162 T10160 arg1Of al.,Lu
R6763 T10162 T10161 arg1Of al.,et
R6764 T10162 T10163 arg1Of al.,","
R6765 T10164 T10163 arg2Of unpublished,","
R6766 T10165 T10159 arg3Of ),(
R6767 T10169 T10168 arg1Of inhibition,specific
R6768 T10169 T10170 arg1Of inhibition,of
R6769 T10169 T10172 arg1Of inhibition,by
R6770 T10169 T10174 arg1Of inhibition,enhances
R6771 T10171 T10170 arg2Of MEK,of
R6772 T10173 T10172 arg2Of selumetinib,by
R6773 T10174 T10166 arg1Of enhances,Indeed
R6774 T10174 T10167 arg1Of enhances,","
R6775 T10174 T10181 arg1Of enhances,(
R6776 T10178 T10174 arg2Of death,enhances
R6777 T10178 T10175 arg1Of death,TMZ-induced
R6778 T10178 T10176 arg1Of death,cancer
R6779 T10178 T10177 arg1Of death,cell
R6780 T10178 T10180 arg1Of death,vivo
R6781 T10180 T10179 arg1Of vivo,in
R6782 T10182 T10181 arg2Of Holt,(
R6783 T10182 T10183 arg1Of Holt,et
R6784 T10182 T10184 arg1Of Holt,al.
R6785 T10182 T10185 arg1Of Holt,","
R6786 T10186 T10185 arg2Of 2012,","
R6787 T10187 T10181 arg3Of ),(
R6788 T10189 T10188 arg1Of factors,Serum
R6789 T10189 T10190 arg1Of factors,can
R6790 T10189 T10191 arg1Of factors,be
R6791 T10189 T10192 arg2Of factors,utilized
R6792 T10192 T10190 arg2Of utilized,can
R6793 T10192 T10191 arg2Of utilized,be
R6794 T10192 T10193 arg1Of utilized,for
R6795 T10194 T10193 arg2Of blocking,for
R6796 T10196 T10194 arg2Of growth,blocking
R6797 T10196 T10195 arg1Of growth,cancer
R6798 T10198 T10197 arg2Of example,For
R6799 T10202 T10200 arg1Of C1q,serum
R6800 T10202 T10201 arg1Of C1q,complement
R6801 T10202 T10203 arg1Of C1q,induces
R6802 T10203 T10197 arg1Of induces,For
R6803 T10203 T10199 arg1Of induces,","
R6804 T10204 T10203 arg2Of apoptosis,induces
R6805 T10204 T10205 arg1Of apoptosis,of
R6806 T10204 T10211 arg1Of apoptosis,without
R6807 T10207 T10206 arg1Of cancer,prostate
R6808 T10207 T10208 arg1Of cancer,and
R6809 T10208 T10205 arg2Of and,of
R6810 T10210 T10208 arg2Of cells,and
R6811 T10210 T10209 arg1Of cells,neuroblastomas
R6812 T10212 T10211 arg2Of participation,without
R6813 T10212 T10213 arg1Of participation,of
R6814 T10215 T10213 arg2Of proteins,of
R6815 T10215 T10214 arg1Of proteins,downstream
R6816 T10215 T10216 arg1Of proteins,in
R6817 T10220 T10216 arg2Of pathway,in
R6818 T10220 T10217 arg1Of pathway,the
R6819 T10220 T10218 arg1Of pathway,classical
R6820 T10220 T10219 arg1Of pathway,activation
R6821 T10220 T10221 arg1Of pathway,(
R6822 T10222 T10221 arg2Of Hong,(
R6823 T10222 T10223 arg1Of Hong,et
R6824 T10222 T10224 arg1Of Hong,al.
R6825 T10222 T10225 arg1Of Hong,","
R6826 T10226 T10225 arg2Of 2009,","
R6827 T10227 T10221 arg3Of ),(
R6828 T10230 T10228 arg2Of event,In
R6829 T10230 T10229 arg1Of event,this
R6830 T10233 T10232 arg1Of WWOX,ectopic
R6831 T10233 T10234 arg1Of WWOX,is
R6832 T10233 T10235 arg2Of WWOX,activated
R6833 T10233 T10237 arg1Of WWOX,inducing
R6834 T10235 T10228 arg1Of activated,In
R6835 T10235 T10231 arg1Of activated,","
R6836 T10235 T10234 arg2Of activated,is
R6837 T10235 T10236 arg1Of activated,for
R6838 T10237 T10236 arg2Of inducing,for
R6839 T10238 T10237 arg2Of apoptosis,inducing