Id |
Subject |
Object |
Predicate |
Lexical cue |
T10069 |
0-7 |
IN |
denotes |
Whether |
T10070 |
8-12 |
NN |
denotes |
WWOX |
T10071 |
13-20 |
VB |
denotes |
affects |
T10072 |
21-24 |
NN |
denotes |
TMZ |
T10073 |
25-36 |
NN |
denotes |
sensitivity |
T10074 |
37-40 |
VB |
denotes |
has |
T10075 |
41-46 |
RB |
denotes |
never |
T10076 |
47-51 |
VB |
denotes |
been |
T10077 |
52-62 |
VB |
denotes |
determined |
T10078 |
64-71 |
NN |
denotes |
Binding |
T10079 |
72-80 |
NN |
denotes |
proteins |
T10080 |
81-84 |
IN |
denotes |
for |
T10081 |
85-89 |
NN |
denotes |
WWOX |
T10082 |
90-96 |
CC |
denotes |
and/or |
T10083 |
97-100 |
NN |
denotes |
p53 |
T10084 |
101-104 |
VB |
denotes |
are |
T10085 |
105-111 |
JJ |
denotes |
likely |
T10086 |
112-114 |
TO |
denotes |
to |
T10087 |
115-121 |
VB |
denotes |
affect |
T10088 |
122-131 |
NN |
denotes |
apoptosis |
T10089 |
132-135 |
CC |
denotes |
and |
T10090 |
136-139 |
NN |
denotes |
TMZ |
T10091 |
140-151 |
NN |
denotes |
sensitivity |
T10092 |
152-154 |
IN |
denotes |
in |
T10093 |
155-158 |
NN |
denotes |
GBM |
T10094 |
159-164 |
NN |
denotes |
cells |
T10095 |
166-170 |
NN |
denotes |
WWOX |
T10096 |
171-176 |
VB |
denotes |
binds |
T10097 |
177-180 |
NN |
denotes |
MEK |
T10098 |
180-181 |
-COMMA- |
denotes |
, |
T10099 |
182-185 |
CC |
denotes |
and |
T10100 |
186-190 |
IN |
denotes |
that |
T10101 |
191-194 |
NN |
denotes |
PMA |
T10102 |
195-206 |
VB |
denotes |
dissociates |
T10103 |
207-211 |
DT |
denotes |
this |
T10104 |
212-219 |
NN |
denotes |
complex |
T10105 |
220-223 |
IN |
denotes |
for |
T10106 |
224-231 |
VB |
denotes |
causing |
T10107 |
232-241 |
NN |
denotes |
apoptosis |
T10108 |
242-244 |
IN |
denotes |
of |
T10109 |
245-246 |
NN |
denotes |
T |
T10110 |
247-255 |
NN |
denotes |
leukemia |
T10111 |
256-261 |
NN |
denotes |
cells |
T10112 |
262-263 |
-LRB- |
denotes |
( |
T10113 |
263-266 |
NNP |
denotes |
Lin |
T10114 |
267-269 |
FW |
denotes |
et |
T10115 |
270-273 |
FW |
denotes |
al. |
T10116 |
273-274 |
-COMMA- |
denotes |
, |
T10117 |
275-279 |
CD |
denotes |
2011 |
T10118 |
279-280 |
-RRB- |
denotes |
) |
T10119 |
282-286 |
RB |
denotes |
Thus |
T10120 |
286-287 |
-COMMA- |
denotes |
, |
T10121 |
288-299 |
JJ |
denotes |
appropriate |
T10122 |
300-309 |
NN |
denotes |
chemicals |
T10123 |
309-310 |
-COMMA- |
denotes |
, |
T10124 |
311-316 |
WDT |
denotes |
which |
T10125 |
317-322 |
VB |
denotes |
break |
T10126 |
323-328 |
RP |
denotes |
apart |
T10127 |
329-332 |
DT |
denotes |
the |
T10128 |
333-341 |
NN |
denotes |
WWOX/MEK |
T10129 |
342-349 |
NN |
denotes |
complex |
T10130 |
349-350 |
-COMMA- |
denotes |
, |
T10131 |
351-354 |
VB |
denotes |
are |
T10132 |
355-363 |
VB |
denotes |
expected |
T10133 |
364-366 |
TO |
denotes |
to |
T10134 |
367-372 |
VB |
denotes |
cause |
T10135 |
373-376 |
NN |
denotes |
GBM |
T10136 |
377-381 |
NN |
denotes |
cell |
T10137 |
382-387 |
NN |
denotes |
death |
T10138 |
389-400 |
JJ |
denotes |
Preliminary |
T10139 |
401-408 |
NN |
denotes |
studies |
T10140 |
409-413 |
IN |
denotes |
from |
T10141 |
414-417 |
PRP-DOLLAR- |
denotes |
our |
T10142 |
418-427 |
NN |
denotes |
screening |
T10143 |
428-430 |
IN |
denotes |
of |
T10144 |
431-440 |
NN |
denotes |
chemicals |
T10145 |
441-445 |
VB |
denotes |
have |
T10146 |
446-454 |
VB |
denotes |
selected |
T10147 |
455-462 |
JJ |
denotes |
certain |
T10148 |
463-468 |
JJ |
denotes |
small |
T10149 |
469-478 |
NN |
denotes |
molecules |
T10150 |
479-483 |
WDT |
denotes |
that |
T10151 |
484-490 |
VB |
denotes |
induce |
T10152 |
491-500 |
NN |
denotes |
apoptosis |
T10153 |
501-503 |
IN |
denotes |
of |
T10154 |
504-508 |
JJ |
denotes |
many |
T10155 |
509-514 |
NN |
denotes |
types |
T10156 |
515-517 |
IN |
denotes |
of |
T10157 |
518-524 |
NN |
denotes |
cancer |
T10158 |
525-530 |
NN |
denotes |
cells |
T10159 |
531-532 |
-LRB- |
denotes |
( |
T10160 |
532-534 |
FW |
denotes |
Lu |
T10161 |
535-537 |
FW |
denotes |
et |
T10162 |
538-541 |
FW |
denotes |
al. |
T10163 |
541-542 |
-COMMA- |
denotes |
, |
T10164 |
543-554 |
JJ |
denotes |
unpublished |
T10165 |
554-555 |
-RRB- |
denotes |
) |
T10166 |
557-563 |
RB |
denotes |
Indeed |
T10167 |
563-564 |
-COMMA- |
denotes |
, |
T10168 |
565-573 |
JJ |
denotes |
specific |
T10169 |
574-584 |
NN |
denotes |
inhibition |
T10170 |
585-587 |
IN |
denotes |
of |
T10171 |
588-591 |
NN |
denotes |
MEK |
T10172 |
592-594 |
IN |
denotes |
by |
T10173 |
595-606 |
NN |
denotes |
selumetinib |
T10174 |
607-615 |
VB |
denotes |
enhances |
T10175 |
616-627 |
JJ |
denotes |
TMZ-induced |
T10176 |
628-634 |
NN |
denotes |
cancer |
T10177 |
635-639 |
NN |
denotes |
cell |
T10178 |
640-645 |
NN |
denotes |
death |
T10179 |
646-648 |
FW |
denotes |
in |
T10180 |
649-653 |
FW |
denotes |
vivo |
T10181 |
654-655 |
-LRB- |
denotes |
( |
T10182 |
655-659 |
NNP |
denotes |
Holt |
T10183 |
660-662 |
FW |
denotes |
et |
T10184 |
663-666 |
FW |
denotes |
al. |
T10185 |
666-667 |
-COMMA- |
denotes |
, |
T10186 |
668-672 |
CD |
denotes |
2012 |
T10187 |
672-673 |
-RRB- |
denotes |
) |
T10188 |
675-680 |
NN |
denotes |
Serum |
T10189 |
681-688 |
NN |
denotes |
factors |
T10190 |
689-692 |
MD |
denotes |
can |
T10191 |
693-695 |
VB |
denotes |
be |
T10192 |
696-704 |
VB |
denotes |
utilized |
T10193 |
705-708 |
IN |
denotes |
for |
T10194 |
709-717 |
VB |
denotes |
blocking |
T10195 |
718-724 |
NN |
denotes |
cancer |
T10196 |
725-731 |
NN |
denotes |
growth |
T10197 |
733-736 |
IN |
denotes |
For |
T10198 |
737-744 |
NN |
denotes |
example |
T10199 |
744-745 |
-COMMA- |
denotes |
, |
T10200 |
746-751 |
NN |
denotes |
serum |
T10201 |
752-762 |
NN |
denotes |
complement |
T10202 |
763-766 |
NN |
denotes |
C1q |
T10203 |
767-774 |
VB |
denotes |
induces |
T10204 |
775-784 |
NN |
denotes |
apoptosis |
T10205 |
785-787 |
IN |
denotes |
of |
T10206 |
788-796 |
NN |
denotes |
prostate |
T10207 |
797-803 |
NN |
denotes |
cancer |
T10208 |
804-807 |
CC |
denotes |
and |
T10209 |
808-822 |
NN |
denotes |
neuroblastomas |
T10210 |
823-828 |
NN |
denotes |
cells |
T10211 |
829-836 |
IN |
denotes |
without |
T10212 |
837-850 |
NN |
denotes |
participation |
T10213 |
851-853 |
IN |
denotes |
of |
T10214 |
854-864 |
JJ |
denotes |
downstream |
T10215 |
865-873 |
NN |
denotes |
proteins |
T10216 |
874-876 |
IN |
denotes |
in |
T10217 |
877-880 |
DT |
denotes |
the |
T10218 |
881-890 |
JJ |
denotes |
classical |
T10219 |
891-901 |
NN |
denotes |
activation |
T10220 |
902-909 |
NN |
denotes |
pathway |
T10221 |
910-911 |
-LRB- |
denotes |
( |
T10222 |
911-915 |
NNP |
denotes |
Hong |
T10223 |
916-918 |
FW |
denotes |
et |
T10224 |
919-922 |
FW |
denotes |
al. |
T10225 |
922-923 |
-COMMA- |
denotes |
, |
T10226 |
924-928 |
CD |
denotes |
2009 |
T10227 |
928-929 |
-RRB- |
denotes |
) |
T10228 |
931-933 |
IN |
denotes |
In |
T10229 |
934-938 |
DT |
denotes |
this |
T10230 |
939-944 |
NN |
denotes |
event |
T10231 |
944-945 |
-COMMA- |
denotes |
, |
T10232 |
946-953 |
JJ |
denotes |
ectopic |
T10233 |
954-958 |
NN |
denotes |
WWOX |
T10234 |
959-961 |
VB |
denotes |
is |
T10235 |
962-971 |
VB |
denotes |
activated |
T10236 |
972-975 |
IN |
denotes |
for |
T10237 |
976-984 |
VB |
denotes |
inducing |
T10238 |
985-994 |
NN |
denotes |
apoptosis |
R6669 |
T10070 |
T10071 |
arg1Of |
WWOX,affects |
R6670 |
T10071 |
T10069 |
arg1Of |
affects,Whether |
R6671 |
T10071 |
T10074 |
arg1Of |
affects,has |
R6672 |
T10071 |
T10076 |
arg1Of |
affects,been |
R6673 |
T10071 |
T10077 |
arg2Of |
affects,determined |
R6674 |
T10073 |
T10071 |
arg2Of |
sensitivity,affects |
R6675 |
T10073 |
T10072 |
arg1Of |
sensitivity,TMZ |
R6676 |
T10077 |
T10074 |
arg2Of |
determined,has |
R6677 |
T10077 |
T10075 |
arg1Of |
determined,never |
R6678 |
T10077 |
T10076 |
arg2Of |
determined,been |
R6679 |
T10079 |
T10078 |
arg1Of |
proteins,Binding |
R6680 |
T10079 |
T10080 |
arg1Of |
proteins,for |
R6681 |
T10079 |
T10084 |
arg1Of |
proteins,are |
R6682 |
T10079 |
T10085 |
arg1Of |
proteins,likely |
R6683 |
T10081 |
T10082 |
arg1Of |
WWOX,and/or |
R6684 |
T10082 |
T10080 |
arg2Of |
and/or,for |
R6685 |
T10083 |
T10082 |
arg2Of |
p53,and/or |
R6686 |
T10085 |
T10084 |
arg2Of |
likely,are |
R6687 |
T10087 |
T10085 |
arg2Of |
affect,likely |
R6688 |
T10087 |
T10086 |
arg1Of |
affect,to |
R6689 |
T10088 |
T10089 |
arg1Of |
apoptosis,and |
R6690 |
T10089 |
T10087 |
arg2Of |
and,affect |
R6691 |
T10089 |
T10092 |
arg1Of |
and,in |
R6692 |
T10091 |
T10089 |
arg2Of |
sensitivity,and |
R6693 |
T10091 |
T10090 |
arg1Of |
sensitivity,TMZ |
R6694 |
T10094 |
T10092 |
arg2Of |
cells,in |
R6695 |
T10094 |
T10093 |
arg1Of |
cells,GBM |
R6696 |
T10095 |
T10096 |
arg1Of |
WWOX,binds |
R6697 |
T10096 |
T10099 |
arg1Of |
binds,and |
R6698 |
T10097 |
T10096 |
arg2Of |
MEK,binds |
R6699 |
T10099 |
T10098 |
arg1Of |
and,"," |
R6700 |
T10101 |
T10102 |
arg1Of |
PMA,dissociates |
R6701 |
T10102 |
T10099 |
arg2Of |
dissociates,and |
R6702 |
T10102 |
T10100 |
arg1Of |
dissociates,that |
R6703 |
T10104 |
T10102 |
arg2Of |
complex,dissociates |
R6704 |
T10104 |
T10103 |
arg1Of |
complex,this |
R6705 |
T10104 |
T10105 |
arg1Of |
complex,for |
R6706 |
T10106 |
T10105 |
arg2Of |
causing,for |
R6707 |
T10106 |
T10112 |
arg1Of |
causing,( |
R6708 |
T10107 |
T10106 |
arg2Of |
apoptosis,causing |
R6709 |
T10107 |
T10108 |
arg1Of |
apoptosis,of |
R6710 |
T10111 |
T10108 |
arg2Of |
cells,of |
R6711 |
T10111 |
T10109 |
arg1Of |
cells,T |
R6712 |
T10111 |
T10110 |
arg1Of |
cells,leukemia |
R6713 |
T10113 |
T10112 |
arg2Of |
Lin,( |
R6714 |
T10113 |
T10114 |
arg1Of |
Lin,et |
R6715 |
T10113 |
T10115 |
arg1Of |
Lin,al. |
R6716 |
T10113 |
T10116 |
arg1Of |
Lin,"," |
R6717 |
T10117 |
T10116 |
arg2Of |
2011,"," |
R6718 |
T10118 |
T10112 |
arg3Of |
),( |
R6719 |
T10122 |
T10121 |
arg1Of |
chemicals,appropriate |
R6720 |
T10122 |
T10123 |
arg1Of |
chemicals,"," |
R6721 |
T10122 |
T10124 |
arg1Of |
chemicals,which |
R6722 |
T10122 |
T10125 |
arg1Of |
chemicals,break |
R6723 |
T10122 |
T10131 |
arg1Of |
chemicals,are |
R6724 |
T10122 |
T10132 |
arg2Of |
chemicals,expected |
R6725 |
T10122 |
T10134 |
arg1Of |
chemicals,cause |
R6726 |
T10125 |
T10126 |
arg1Of |
break,apart |
R6727 |
T10129 |
T10125 |
arg2Of |
complex,break |
R6728 |
T10129 |
T10127 |
arg1Of |
complex,the |
R6729 |
T10129 |
T10128 |
arg1Of |
complex,WWOX/MEK |
R6730 |
T10132 |
T10119 |
arg1Of |
expected,Thus |
R6731 |
T10132 |
T10120 |
arg1Of |
expected,"," |
R6732 |
T10132 |
T10130 |
arg1Of |
expected,"," |
R6733 |
T10132 |
T10131 |
arg2Of |
expected,are |
R6734 |
T10134 |
T10132 |
arg3Of |
cause,expected |
R6735 |
T10134 |
T10133 |
arg1Of |
cause,to |
R6736 |
T10137 |
T10134 |
arg2Of |
death,cause |
R6737 |
T10137 |
T10135 |
arg1Of |
death,GBM |
R6738 |
T10137 |
T10136 |
arg1Of |
death,cell |
R6739 |
T10139 |
T10138 |
arg1Of |
studies,Preliminary |
R6740 |
T10139 |
T10140 |
arg1Of |
studies,from |
R6741 |
T10139 |
T10145 |
arg1Of |
studies,have |
R6742 |
T10139 |
T10146 |
arg1Of |
studies,selected |
R6743 |
T10142 |
T10140 |
arg2Of |
screening,from |
R6744 |
T10142 |
T10141 |
arg1Of |
screening,our |
R6745 |
T10142 |
T10143 |
arg1Of |
screening,of |
R6746 |
T10144 |
T10143 |
arg2Of |
chemicals,of |
R6747 |
T10146 |
T10145 |
arg2Of |
selected,have |
R6748 |
T10149 |
T10146 |
arg2Of |
molecules,selected |
R6749 |
T10149 |
T10147 |
arg1Of |
molecules,certain |
R6750 |
T10149 |
T10148 |
arg1Of |
molecules,small |
R6751 |
T10149 |
T10150 |
arg1Of |
molecules,that |
R6752 |
T10149 |
T10151 |
arg1Of |
molecules,induce |
R6753 |
T10152 |
T10151 |
arg2Of |
apoptosis,induce |
R6754 |
T10152 |
T10153 |
arg1Of |
apoptosis,of |
R6755 |
T10155 |
T10153 |
arg2Of |
types,of |
R6756 |
T10155 |
T10154 |
arg1Of |
types,many |
R6757 |
T10155 |
T10156 |
arg1Of |
types,of |
R6758 |
T10155 |
T10159 |
arg1Of |
types,( |
R6759 |
T10158 |
T10156 |
arg2Of |
cells,of |
R6760 |
T10158 |
T10157 |
arg1Of |
cells,cancer |
R6761 |
T10162 |
T10159 |
arg2Of |
al.,( |
R6762 |
T10162 |
T10160 |
arg1Of |
al.,Lu |
R6763 |
T10162 |
T10161 |
arg1Of |
al.,et |
R6764 |
T10162 |
T10163 |
arg1Of |
al.,"," |
R6765 |
T10164 |
T10163 |
arg2Of |
unpublished,"," |
R6766 |
T10165 |
T10159 |
arg3Of |
),( |
R6767 |
T10169 |
T10168 |
arg1Of |
inhibition,specific |
R6768 |
T10169 |
T10170 |
arg1Of |
inhibition,of |
R6769 |
T10169 |
T10172 |
arg1Of |
inhibition,by |
R6770 |
T10169 |
T10174 |
arg1Of |
inhibition,enhances |
R6771 |
T10171 |
T10170 |
arg2Of |
MEK,of |
R6772 |
T10173 |
T10172 |
arg2Of |
selumetinib,by |
R6773 |
T10174 |
T10166 |
arg1Of |
enhances,Indeed |
R6774 |
T10174 |
T10167 |
arg1Of |
enhances,"," |
R6775 |
T10174 |
T10181 |
arg1Of |
enhances,( |
R6776 |
T10178 |
T10174 |
arg2Of |
death,enhances |
R6777 |
T10178 |
T10175 |
arg1Of |
death,TMZ-induced |
R6778 |
T10178 |
T10176 |
arg1Of |
death,cancer |
R6779 |
T10178 |
T10177 |
arg1Of |
death,cell |
R6780 |
T10178 |
T10180 |
arg1Of |
death,vivo |
R6781 |
T10180 |
T10179 |
arg1Of |
vivo,in |
R6782 |
T10182 |
T10181 |
arg2Of |
Holt,( |
R6783 |
T10182 |
T10183 |
arg1Of |
Holt,et |
R6784 |
T10182 |
T10184 |
arg1Of |
Holt,al. |
R6785 |
T10182 |
T10185 |
arg1Of |
Holt,"," |
R6786 |
T10186 |
T10185 |
arg2Of |
2012,"," |
R6787 |
T10187 |
T10181 |
arg3Of |
),( |
R6788 |
T10189 |
T10188 |
arg1Of |
factors,Serum |
R6789 |
T10189 |
T10190 |
arg1Of |
factors,can |
R6790 |
T10189 |
T10191 |
arg1Of |
factors,be |
R6791 |
T10189 |
T10192 |
arg2Of |
factors,utilized |
R6792 |
T10192 |
T10190 |
arg2Of |
utilized,can |
R6793 |
T10192 |
T10191 |
arg2Of |
utilized,be |
R6794 |
T10192 |
T10193 |
arg1Of |
utilized,for |
R6795 |
T10194 |
T10193 |
arg2Of |
blocking,for |
R6796 |
T10196 |
T10194 |
arg2Of |
growth,blocking |
R6797 |
T10196 |
T10195 |
arg1Of |
growth,cancer |
R6798 |
T10198 |
T10197 |
arg2Of |
example,For |
R6799 |
T10202 |
T10200 |
arg1Of |
C1q,serum |
R6800 |
T10202 |
T10201 |
arg1Of |
C1q,complement |
R6801 |
T10202 |
T10203 |
arg1Of |
C1q,induces |
R6802 |
T10203 |
T10197 |
arg1Of |
induces,For |
R6803 |
T10203 |
T10199 |
arg1Of |
induces,"," |
R6804 |
T10204 |
T10203 |
arg2Of |
apoptosis,induces |
R6805 |
T10204 |
T10205 |
arg1Of |
apoptosis,of |
R6806 |
T10204 |
T10211 |
arg1Of |
apoptosis,without |
R6807 |
T10207 |
T10206 |
arg1Of |
cancer,prostate |
R6808 |
T10207 |
T10208 |
arg1Of |
cancer,and |
R6809 |
T10208 |
T10205 |
arg2Of |
and,of |
R6810 |
T10210 |
T10208 |
arg2Of |
cells,and |
R6811 |
T10210 |
T10209 |
arg1Of |
cells,neuroblastomas |
R6812 |
T10212 |
T10211 |
arg2Of |
participation,without |
R6813 |
T10212 |
T10213 |
arg1Of |
participation,of |
R6814 |
T10215 |
T10213 |
arg2Of |
proteins,of |
R6815 |
T10215 |
T10214 |
arg1Of |
proteins,downstream |
R6816 |
T10215 |
T10216 |
arg1Of |
proteins,in |
R6817 |
T10220 |
T10216 |
arg2Of |
pathway,in |
R6818 |
T10220 |
T10217 |
arg1Of |
pathway,the |
R6819 |
T10220 |
T10218 |
arg1Of |
pathway,classical |
R6820 |
T10220 |
T10219 |
arg1Of |
pathway,activation |
R6821 |
T10220 |
T10221 |
arg1Of |
pathway,( |
R6822 |
T10222 |
T10221 |
arg2Of |
Hong,( |
R6823 |
T10222 |
T10223 |
arg1Of |
Hong,et |
R6824 |
T10222 |
T10224 |
arg1Of |
Hong,al. |
R6825 |
T10222 |
T10225 |
arg1Of |
Hong,"," |
R6826 |
T10226 |
T10225 |
arg2Of |
2009,"," |
R6827 |
T10227 |
T10221 |
arg3Of |
),( |
R6828 |
T10230 |
T10228 |
arg2Of |
event,In |
R6829 |
T10230 |
T10229 |
arg1Of |
event,this |
R6830 |
T10233 |
T10232 |
arg1Of |
WWOX,ectopic |
R6831 |
T10233 |
T10234 |
arg1Of |
WWOX,is |
R6832 |
T10233 |
T10235 |
arg2Of |
WWOX,activated |
R6833 |
T10233 |
T10237 |
arg1Of |
WWOX,inducing |
R6834 |
T10235 |
T10228 |
arg1Of |
activated,In |
R6835 |
T10235 |
T10231 |
arg1Of |
activated,"," |
R6836 |
T10235 |
T10234 |
arg2Of |
activated,is |
R6837 |
T10235 |
T10236 |
arg1Of |
activated,for |
R6838 |
T10237 |
T10236 |
arg2Of |
inducing,for |
R6839 |
T10238 |
T10237 |
arg2Of |
apoptosis,inducing |