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PMC:3586680 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T166 0-5 NN denotes Tumor
T167 6-16 NN denotes Suppressor
T168 17-21 NN denotes WWOX
T169 22-25 CC denotes and
T170 26-29 NN denotes p53
T171 30-41 NN denotes Alterations
T172 42-45 CC denotes and
T173 46-50 NNP denotes Drug
T174 51-61 NNP denotes Resistance
T175 62-64 IN denotes in
T176 65-78 NN denotes Glioblastomas
T177 89-94 NN denotes Tumor
T178 95-105 NN denotes suppressor
T179 106-109 NN denotes p53
T180 110-113 VB denotes are
T181 114-124 RB denotes frequently
T182 125-132 VB denotes mutated
T183 133-135 IN denotes in
T184 136-149 NN denotes glioblastomas
T185 150-151 -LRB- denotes (
T186 151-155 NN denotes GBMs
T187 155-156 -RRB- denotes )
T188 157-160 CC denotes and
T189 161-168 VB denotes appears
T190 169-171 TO denotes to
T191 172-182 VB denotes contribute
T192 182-183 -COMMA- denotes ,
T193 184-186 IN denotes in
T194 187-191 NN denotes part
T195 191-192 -COMMA- denotes ,
T196 193-195 TO denotes to
T197 196-206 NN denotes resistance
T198 207-209 TO denotes to
T199 210-222 NN denotes temozolomide
T200 223-224 -LRB- denotes (
T201 224-227 NN denotes TMZ
T202 227-228 -RRB- denotes )
T203 229-232 CC denotes and
T204 233-244 JJ denotes therapeutic
T205 245-250 NN denotes drugs
T206 252-254 JJ denotes WW
T207 255-272 JJ denotes domain-containing
T208 273-287 NN denotes oxidoreductase
T209 288-292 NN denotes WWOX
T210 293-294 -LRB- denotes (
T211 294-297 NN denotes FOR
T212 298-300 CC denotes or
T213 301-305 NN denotes WOX1
T214 305-306 -RRB- denotes )
T215 307-309 VB denotes is
T216 310-311 DT denotes a
T217 312-324 JJ denotes proapoptotic
T218 325-332 NN denotes protein
T219 333-336 CC denotes and
T220 337-339 VB denotes is
T221 340-350 VB denotes considered
T222 351-353 IN denotes as
T223 354-355 DT denotes a
T224 356-361 NN denotes tumor
T225 362-372 NN denotes suppressor
T226 374-378 NN denotes Loss
T227 379-381 IN denotes of
T228 382-386 NN denotes WWOX
T229 387-391 NN denotes gene
T230 392-402 NN denotes expression
T231 403-405 VB denotes is
T232 406-416 RB denotes frequently
T233 417-421 VB denotes seen
T234 422-424 IN denotes in
T235 425-434 JJ denotes malignant
T236 435-441 NN denotes cancer
T237 442-447 NN denotes cells
T238 448-451 JJ denotes due
T239 452-454 TO denotes to
T240 455-463 NN denotes promoter
T241 464-480 NN denotes hypermethylation
T242 480-481 -COMMA- denotes ,
T243 482-489 JJ denotes genetic
T244 490-501 NN denotes alterations
T245 501-502 -COMMA- denotes ,
T246 503-506 CC denotes and
T247 507-520 JJ denotes translational
T248 521-529 NN denotes blockade
T249 531-543 RB denotes Intriguingly
T250 543-544 -COMMA- denotes ,
T251 545-552 JJ denotes ectopic
T252 553-563 NN denotes expression
T253 564-566 IN denotes of
T254 567-571 JJ denotes wild
T255 572-576 NN denotes type
T256 577-581 NN denotes WWOX
T257 582-596 RB denotes preferentially
T258 597-604 VB denotes induces
T259 605-614 NN denotes apoptosis
T260 615-617 IN denotes in
T261 618-623 JJ denotes human
T262 624-636 NN denotes glioblastoma
T263 637-642 NN denotes cells
T264 643-652 VB denotes harboring
T265 653-659 JJ denotes mutant
T266 660-663 NN denotes p53
T267 665-669 NN denotes WWOX
T268 670-672 VB denotes is
T269 673-678 VB denotes known
T270 679-681 TO denotes to
T271 682-692 RB denotes physically
T272 693-697 VB denotes bind
T273 698-701 CC denotes and
T274 702-711 VB denotes stabilize
T275 712-716 JJ denotes wild
T276 717-721 NN denotes type
T277 722-725 NN denotes p53
T278 727-731 RB denotes Here
T279 731-732 -COMMA- denotes ,
T280 733-735 PRP denotes we
T281 736-743 VB denotes provide
T282 744-746 DT denotes an
T283 747-755 NN denotes overview
T284 756-759 IN denotes for
T285 760-763 DT denotes the
T286 764-771 VB denotes updated
T287 772-781 NN denotes knowledge
T288 782-784 IN denotes in
T289 785-788 NN denotes p53
T290 789-792 CC denotes and
T291 793-797 NN denotes WWOX
T292 797-798 -COMMA- denotes ,
T293 799-802 CC denotes and
T294 803-812 VB denotes postulate
T295 813-822 JJ denotes potential
T296 823-832 NN denotes scenarios
T297 833-837 IN denotes that
T298 838-842 JJ denotes wild
T299 843-847 NN denotes type
T300 848-851 CC denotes and
T301 852-858 JJ denotes mutant
T302 859-862 NN denotes p53
T303 862-863 -COMMA- denotes ,
T304 864-866 CC denotes or
T305 867-875 NN denotes isoforms
T306 875-876 -COMMA- denotes ,
T307 877-885 VB denotes modulate
T308 886-889 DT denotes the
T309 890-899 JJ denotes apoptotic
T310 900-908 NN denotes function
T311 909-911 IN denotes of
T312 912-916 NN denotes WWOX
T313 918-920 PRP denotes We
T314 921-928 VB denotes propose
T315 929-933 IN denotes that
T316 934-944 VB denotes triggering
T317 945-949 NN denotes WWOX
T318 950-960 NN denotes activation
T319 961-963 IN denotes by
T320 964-975 JJ denotes therapeutic
T321 976-981 NN denotes drugs
T322 982-987 IN denotes under
T323 988-991 NN denotes p53
T324 992-1002 JJ denotes functional
T325 1003-1013 NN denotes deficiency
T326 1014-1016 VB denotes is
T327 1017-1023 VB denotes needed
T328 1024-1026 TO denotes to
T329 1027-1035 VB denotes overcome
T330 1036-1039 NN denotes TMZ
T331 1040-1050 NN denotes resistance
T332 1051-1054 CC denotes and
T333 1055-1061 VB denotes induce
T334 1062-1065 NN denotes GBM
T335 1066-1070 NN denotes cell
T336 1071-1076 NN denotes death
T910 1137-1149 NN denotes Glioblastoma
T911 1150-1160 JJ denotes multiforme
T912 1161-1169 NN denotes afflicts
T913 1170-1176 CD denotes 12,500
T914 1177-1180 JJ denotes new
T915 1181-1189 NN denotes patients
T916 1190-1192 IN denotes in
T917 1193-1196 DT denotes the
T918 1197-1201 NNP denotes U.S.
T919 1202-1210 RB denotes annually
T920 1211-1212 -LRB- denotes (
T921 1212-1220 NNP denotes Friedman
T922 1221-1223 FW denotes et
T923 1224-1227 FW denotes al.
T924 1227-1228 -COMMA- denotes ,
T925 1229-1233 CD denotes 2000
T926 1233-1234 -COLON- denotes ;
T927 1235-1240 NNP denotes Stupp
T928 1241-1243 FW denotes et
T929 1244-1247 FW denotes al.
T930 1247-1248 -COMMA- denotes ,
T931 1249-1253 CD denotes 2009
T932 1253-1254 -COLON- denotes ;
T933 1255-1261 NNP denotes Silber
T934 1262-1264 FW denotes et
T935 1265-1268 FW denotes al.
T936 1268-1269 -COMMA- denotes ,
T937 1270-1274 CD denotes 2012
T938 1274-1275 -RRB- denotes )
T939 1277-1289 NN denotes Glioblastoma
T940 1290-1291 -LRB- denotes (
T941 1291-1294 NN denotes GBM
T942 1294-1295 -RRB- denotes )
T943 1296-1298 VB denotes is
T944 1299-1305 RB denotes highly
T945 1306-1312 JJ denotes lethal
T946 1312-1313 -COMMA- denotes ,
T947 1314-1317 CC denotes and
T948 1318-1321 DT denotes the
T949 1322-1329 JJ denotes average
T950 1330-1338 NN denotes survival
T951 1339-1349 NN denotes expectancy
T952 1350-1352 VB denotes is
T953 1353-1364 NN denotes 14.6 months
T954 1364-1365 -COMMA- denotes ,
T955 1366-1369 CC denotes and
T956 1370-1373 DT denotes the
T957 1374-1381 JJ denotes overall
T958 1382-1388 JJ denotes 5-year
T959 1389-1397 NN denotes survival
T960 1398-1402 NN denotes rate
T961 1403-1406 IN denotes for
T962 1407-1410 NN denotes GBM
T963 1411-1413 VB denotes is
T964 1414-1418 RB denotes only
T965 1419-1422 CD denotes 9.8
T966 1422-1423 NN denotes %
T967 1424-1425 -LRB- denotes (
T968 1425-1433 NNP denotes Friedman
T969 1434-1436 FW denotes et
T970 1437-1440 FW denotes al.
T971 1440-1441 -COMMA- denotes ,
T972 1442-1446 CD denotes 2000
T973 1446-1447 -COLON- denotes ;
T974 1448-1453 NNP denotes Stupp
T975 1454-1456 FW denotes et
T976 1457-1460 FW denotes al.
T977 1460-1461 -COMMA- denotes ,
T978 1462-1466 CD denotes 2009
T979 1466-1467 -RRB- denotes )
T980 1469-1473 JJ denotes High
T981 1474-1480 NN denotes levels
T982 1481-1483 IN denotes of
T983 1484-1494 NN denotes resistance
T984 1495-1497 TO denotes to
T985 1498-1505 JJ denotes current
T986 1506-1517 JJ denotes therapeutic
T987 1518-1528 NN denotes modalities
T988 1529-1532 CC denotes and
T989 1533-1539 NN denotes cancer
T990 1540-1547 NN denotes relapse
T991 1548-1551 VB denotes are
T992 1552-1562 RB denotes frequently
T993 1563-1567 VB denotes seen
T994 1568-1570 IN denotes in
T995 1571-1579 NN denotes patients
T996 1580-1581 -LRB- denotes (
T997 1581-1585 NNP denotes Haar
T998 1586-1588 FW denotes et
T999 1589-1592 FW denotes al.
T1000 1592-1593 -COMMA- denotes ,
T1001 1594-1598 CD denotes 2012
T1002 1598-1599 -COLON- denotes ;
T1003 1600-1607 NNP denotes Happold
T1004 1608-1610 FW denotes et
T1005 1611-1614 FW denotes al.
T1006 1614-1615 -COMMA- denotes ,
T1007 1616-1620 CD denotes 2012
T1008 1620-1621 -RRB- denotes )
T1009 1623-1626 DT denotes The
T1010 1627-1634 JJ denotes current
T1011 1635-1643 JJ denotes standard
T1012 1644-1651 NN denotes therapy
T1013 1652-1655 IN denotes for
T1014 1656-1659 NN denotes GBM
T1015 1660-1666 RB denotes mainly
T1016 1667-1675 VB denotes includes
T1017 1676-1683 JJ denotes maximum
T1018 1684-1693 VB denotes debulking
T1019 1694-1701 NN denotes surgery
T1020 1701-1702 -COMMA- denotes ,
T1021 1703-1712 NN denotes radiation
T1022 1712-1713 -COMMA- denotes ,
T1023 1714-1717 CC denotes and
T1024 1718-1727 NN denotes treatment
T1025 1728-1732 IN denotes with
T1026 1733-1736 DT denotes the
T1027 1737-1751 JJ denotes monofunctional
T1028 1752-1762 VB denotes alkylating
T1029 1763-1768 NN denotes agent
T1030 1769-1781 NN denotes temozolomide
T1031 1782-1783 -LRB- denotes (
T1032 1783-1786 NN denotes TMZ
T1033 1786-1787 -RRB- denotes )
T1034 1788-1789 -LRB- denotes (
T1035 1789-1797 NNP denotes Friedman
T1036 1798-1800 FW denotes et
T1037 1801-1804 FW denotes al.
T1038 1804-1805 -COMMA- denotes ,
T1039 1806-1810 CD denotes 2000
T1040 1810-1811 -COLON- denotes ;
T1041 1812-1821 NNP denotes Nishikawa
T1042 1821-1822 -COMMA- denotes ,
T1043 1823-1827 CD denotes 2010
T1044 1827-1828 -RRB- denotes )
T1045 1830-1838 JJ denotes Multiple
T1046 1839-1849 NN denotes mechanisms
T1047 1850-1853 VB denotes are
T1048 1854-1862 VB denotes involved
T1049 1863-1865 IN denotes in
T1050 1866-1869 DT denotes the
T1051 1870-1873 NN denotes TMZ
T1052 1874-1884 NN denotes resistance
T1053 1884-1885 -COMMA- denotes ,
T1054 1886-1891 WDT denotes which
T1055 1892-1895 MD denotes may
T1056 1896-1903 VB denotes include
T1057 1904-1910 NN denotes cancer
T1058 1911-1915 NN denotes stem
T1059 1916-1921 NN denotes cells
T1060 1921-1922 -COMMA- denotes ,
T1061 1923-1932 NN denotes microRNAs
T1062 1932-1933 -COMMA- denotes ,
T1063 1934-1938 NN denotes drug
T1064 1939-1945 NN denotes efflux
T1065 1945-1946 -COMMA- denotes ,
T1066 1947-1950 NN denotes DNA
T1067 1951-1957 NN denotes damage
T1068 1958-1964 NN denotes repair
T1069 1964-1965 -COMMA- denotes ,
T1070 1966-1971 NN denotes tumor
T1071 1972-1977 NN denotes cells
T1072 1978-1983 IN denotes under
T1073 1984-1991 NN denotes hypoxia
T1074 1991-1992 -COMMA- denotes ,
T1075 1993-2000 NN denotes histone
T1076 2001-2014 NN denotes deacetylation
T1077 2014-2015 -COMMA- denotes ,
T1078 2016-2038 JJ denotes epithelial-mesenchymal
T1079 2039-2049 NN denotes transition
T1080 2049-2050 -COMMA- denotes ,
T1081 2051-2056 NN denotes STAT3
T1082 2057-2063 NN denotes kinase
T1083 2063-2064 -COMMA- denotes ,
T1084 2065-2068 CC denotes and
T1085 2069-2073 JJ denotes many
T1086 2074-2080 NN denotes others
T1087 2081-2082 -LRB- denotes (
T1088 2082-2086 NNP denotes Haar
T1089 2087-2089 FW denotes et
T1090 2090-2093 FW denotes al.
T1091 2093-2094 -COMMA- denotes ,
T1092 2095-2099 CD denotes 2012
T1093 2099-2100 -COLON- denotes ;
T1094 2101-2108 NNP denotes Happold
T1095 2109-2111 FW denotes et
T1096 2112-2115 FW denotes al.
T1097 2115-2116 -COMMA- denotes ,
T1098 2117-2121 CD denotes 2012
T1099 2121-2122 -COLON- denotes ;
T1100 2123-2134 NNP denotes Johannessen
T1101 2135-2138 CC denotes and
T1102 2139-2147 NNP denotes Bjerkvig
T1103 2147-2148 -COMMA- denotes ,
T1104 2149-2153 CD denotes 2012
T1105 2153-2154 -COLON- denotes ;
T1106 2155-2162 NNP denotes Kitange
T1107 2163-2165 FW denotes et
T1108 2166-2169 FW denotes al.
T1109 2169-2170 -COMMA- denotes ,
T1110 2171-2175 CD denotes 2012
T1111 2175-2176 -COLON- denotes ;
T1112 2177-2184 NNP denotes Kohsaka
T1113 2185-2187 FW denotes et
T1114 2188-2191 FW denotes al.
T1115 2191-2192 -COMMA- denotes ,
T1116 2193-2197 CD denotes 2012
T1117 2197-2198 -COLON- denotes ;
T1118 2199-2204 NNP denotes Zhang
T1119 2205-2207 FW denotes et
T1120 2208-2211 FW denotes al.
T1121 2211-2212 -COMMA- denotes ,
T1122 2213-2218 NN denotes 2012b
T1123 2218-2219 -RRB- denotes )
T1124 2221-2233 NN denotes Temozolomide
T1125 2234-2241 VB denotes induces
T1126 2242-2252 NN denotes generation
T1127 2253-2255 IN denotes of
T1128 2256-2259 NN denotes DNA
T1129 2260-2267 NN denotes lesions
T1130 2267-2268 -COMMA- denotes ,
T1131 2269-2278 VB denotes including
T1132 2279-2295 NN denotes O6-methylguanine
T1133 2295-2296 -COMMA- denotes ,
T1134 2297-2313 NN denotes N3-methyladenine
T1135 2313-2314 -COMMA- denotes ,
T1136 2315-2318 CC denotes and
T1137 2319-2335 NN denotes N7-methylguanine
T1138 2336-2337 -LRB- denotes (
T1139 2337-2345 NNP denotes Goellner
T1140 2346-2348 FW denotes et
T1141 2349-2352 FW denotes al.
T1142 2352-2353 -COMMA- denotes ,
T1143 2354-2358 CD denotes 2011
T1144 2358-2359 -COLON- denotes ;
T1145 2360-2365 NNP denotes Zhang
T1146 2366-2368 FW denotes et
T1147 2369-2372 FW denotes al.
T1148 2372-2373 -COMMA- denotes ,
T1149 2374-2379 NN denotes 2012b
T1150 2379-2380 -RRB- denotes )
T1151 2382-2385 DT denotes The
T1152 2386-2402 NN denotes O6-methylguanine
T1153 2403-2409 NN denotes lesion
T1154 2410-2412 VB denotes is
T1155 2413-2418 VB denotes known
T1156 2419-2421 TO denotes to
T1157 2422-2429 VB denotes trigger
T1158 2430-2439 NN denotes autophagy
T1159 2439-2440 -COMMA- denotes ,
T1160 2441-2447 RB denotes rather
T1161 2448-2452 IN denotes than
T1162 2453-2462 NN denotes apoptosis
T1163 2462-2463 -COMMA- denotes ,
T1164 2464-2466 TO denotes to
T1165 2467-2472 VB denotes cause
T1166 2473-2477 NN denotes cell
T1167 2478-2483 NN denotes death
T1168 2484-2485 -LRB- denotes (
T1169 2485-2492 NNP denotes Kanzawa
T1170 2493-2495 FW denotes et
T1171 2496-2499 FW denotes al.
T1172 2499-2500 -COMMA- denotes ,
T1173 2501-2505 CD denotes 2003
T1174 2505-2506 -RRB- denotes )
T1175 2508-2512 RB denotes Also
T1176 2512-2513 -COMMA- denotes ,
T1177 2514-2524 NN denotes inhibition
T1178 2525-2527 IN denotes of
T1179 2528-2541 JJ denotes antiapoptotic
T1180 2542-2547 NN denotes Bcl-2
T1181 2548-2550 IN denotes by
T1182 2551-2552 DT denotes a
T1183 2553-2562 NN denotes pan-Bcl-2
T1184 2563-2572 NN denotes inhibitor
T1185 2573-2574 -LRB- denotes (
T1186 2574-2575 LS denotes −
T1187 2575-2576 -RRB- denotes )
T1188 2576-2585 NN denotes -gossypol
T1189 2586-2591 VB denotes leads
T1190 2592-2594 TO denotes to
T1191 2595-2605 JJ denotes autophagic
T1192 2606-2611 NN denotes death
T1193 2612-2614 IN denotes in
T1194 2615-2622 NN denotes gliomas
T1195 2623-2626 CC denotes and
T1196 2627-2635 VB denotes enhances
T1197 2636-2639 DT denotes the
T1198 2640-2646 NN denotes action
T1199 2647-2649 IN denotes of
T1200 2650-2653 NN denotes TMZ
T1201 2654-2655 -LRB- denotes (
T1202 2655-2659 NNP denotes Voss
T1203 2660-2662 FW denotes et
T1204 2663-2666 FW denotes al.
T1205 2666-2667 -COMMA- denotes ,
T1206 2668-2672 CD denotes 2010
T1207 2672-2673 -RRB- denotes )
T1208 2675-2682 RB denotes However
T1209 2682-2683 -COMMA- denotes ,
T1210 2684-2685 DT denotes a
T1211 2686-2692 JJ denotes recent
T1212 2693-2698 NN denotes study
T1213 2699-2711 VB denotes demonstrated
T1214 2712-2716 IN denotes that
T1215 2717-2728 JJ denotes TMZ-induced
T1216 2729-2738 NN denotes autophagy
T1217 2739-2741 VB denotes is
T1218 2742-2754 JJ denotes pro-survival
T1219 2754-2755 -COMMA- denotes ,
T1220 2756-2759 CC denotes and
T1221 2760-2763 MD denotes may
T1222 2764-2769 VB denotes block
T1223 2770-2773 DT denotes the
T1224 2774-2782 JJ denotes eventual
T1225 2783-2792 NN denotes apoptosis
T1226 2793-2795 IN denotes in
T1227 2796-2799 NN denotes GBM
T1228 2800-2805 NN denotes cells
T1229 2806-2807 -LRB- denotes (
T1230 2807-2815 NNP denotes Knizhnik
T1231 2816-2818 FW denotes et
T1232 2819-2822 FW denotes al.
T1233 2822-2823 -COMMA- denotes ,
T1234 2824-2828 CD denotes 2013
T1235 2828-2829 -RRB- denotes )
T1236 2831-2835 RB denotes Also
T1237 2835-2836 -COMMA- denotes ,
T1238 2837-2842 NN denotes MAPO2
T1239 2843-2844 -LRB- denotes (
T1240 2844-2852 NN denotes C1orf201
T1241 2852-2853 -RRB- denotes )
T1242 2854-2858 NN denotes gene
T1243 2859-2871 VB denotes participates
T1244 2872-2874 IN denotes in
T1245 2875-2878 DT denotes the
T1246 2879-2895 NN denotes O6-methylguanine
T1247 2896-2910 JJ denotes lesion-induced
T1248 2911-2920 NN denotes apoptosis
T1249 2921-2922 -LRB- denotes (
T1250 2922-2930 NNP denotes Fujikane
T1251 2931-2933 FW denotes et
T1252 2934-2937 FW denotes al.
T1253 2937-2938 -COMMA- denotes ,
T1254 2939-2943 CD denotes 2012
T1255 2943-2944 -RRB- denotes )
T1256 2946-2951 NN denotes MAPO2
T1257 2952-2956 NN denotes gene
T1258 2957-2964 VB denotes encodes
T1259 2965-2966 DT denotes a
T1260 2967-2972 JJ denotes novel
T1261 2973-2979 JJ denotes 37-kDa
T1262 2980-2987 NN denotes protein
T1263 2989-2991 PRP denotes It
T1264 2992-2994 VB denotes is
T1265 2995-2998 RB denotes not
T1266 2999-3009 VB denotes determined
T1267 3010-3017 IN denotes whether
T1268 3018-3022 DT denotes this
T1269 3023-3027 NN denotes gene
T1270 3028-3030 VB denotes is
T1271 3031-3039 VB denotes involved
T1272 3040-3042 IN denotes in
T1273 3043-3052 NN denotes autophagy
T1274 3054-3057 DT denotes The
T1275 3058-3074 NN denotes O6-methylguanine
T1276 3075-3081 NN denotes lesion
T1277 3082-3084 VB denotes is
T1278 3085-3086 DT denotes a
T1279 3087-3096 NN denotes substrate
T1280 3097-3100 IN denotes for
T1281 3101-3107 JJ denotes direct
T1282 3108-3114 NN denotes repair
T1283 3115-3117 IN denotes by
T1284 3118-3138 NN denotes O6-methylguanine-DNA
T1285 3139-3156 NN denotes methyltransferase
T1286 3157-3158 -LRB- denotes (
T1287 3158-3162 NN denotes MGMT
T1288 3162-3163 -RRB- denotes )
T1289 3164-3165 -LRB- denotes (
T1290 3165-3172 NNP denotes Pollack
T1291 3173-3175 FW denotes et
T1292 3176-3179 FW denotes al.
T1293 3179-3180 -COMMA- denotes ,
T1294 3181-3185 CD denotes 2006
T1295 3185-3186 -COLON- denotes ;
T1296 3187-3191 NNP denotes Hegi
T1297 3192-3194 FW denotes et
T1298 3195-3198 FW denotes al.
T1299 3198-3199 -COMMA- denotes ,
T1300 3200-3204 CD denotes 2008
T1301 3204-3205 -COLON- denotes ;
T1302 3206-3215 NNP denotes Fukushima
T1303 3216-3218 FW denotes et
T1304 3219-3222 FW denotes al.
T1305 3222-3223 -COMMA- denotes ,
T1306 3224-3228 CD denotes 2009
T1307 3228-3229 -COLON- denotes ;
T1308 3230-3235 NNP denotes Zhang
T1309 3236-3238 FW denotes et
T1310 3239-3242 FW denotes al.
T1311 3242-3243 -COMMA- denotes ,
T1312 3244-3249 NN denotes 2012b
T1313 3249-3250 -RRB- denotes )
T1314 3252-3259 IN denotes Without
T1315 3260-3264 NN denotes MGMT
T1316 3265-3271 NN denotes repair
T1317 3271-3272 -COMMA- denotes ,
T1318 3273-3289 NN denotes O6-methylguanine
T1319 3290-3299 VB denotes initiates
T1320 3300-3310 NN denotes activation
T1321 3311-3313 IN denotes of
T1322 3314-3322 NN denotes mismatch
T1323 3323-3339 JJ denotes repair-deficient
T1324 3340-3341 -LRB- denotes (
T1325 3341-3344 NN denotes MMR
T1326 3344-3345 -RRB- denotes )
T1327 3346-3354 NN denotes proteins
T1328 3355-3357 CC denotes or
T1329 3358-3370 JJ denotes Rad3-related
T1330 3371-3378 NN denotes protein
T1331 3379-3385 NN denotes kinase
T1332 3386-3390 WDT denotes that
T1333 3391-3401 RB denotes ultimately
T1334 3402-3407 VB denotes leads
T1335 3408-3410 TO denotes to
T1336 3411-3420 JJ denotes apoptotic
T1337 3421-3425 NN denotes cell
T1338 3426-3431 NN denotes death
T1339 3432-3433 -LRB- denotes (
T1340 3433-3441 NNP denotes Caporali
T1341 3442-3444 FW denotes et
T1342 3445-3448 FW denotes al.
T1343 3448-3449 -COMMA- denotes ,
T1344 3450-3454 CD denotes 2004
T1345 3454-3455 -COLON- denotes ;
T1346 3456-3460 NNP denotes Wang
T1347 3461-3464 CC denotes and
T1348 3465-3473 NNP denotes Edelmann
T1349 3473-3474 -COMMA- denotes ,
T1350 3475-3479 CD denotes 2006
T1351 3479-3480 -COLON- denotes ;
T1352 3481-3485 NNP denotes Roos
T1353 3486-3488 FW denotes et
T1354 3489-3492 FW denotes al.
T1355 3492-3493 -COMMA- denotes ,
T1356 3494-3498 CD denotes 2007
T1357 3498-3499 -RRB- denotes )
T1358 3501-3505 JJ denotes High
T1359 3506-3516 NN denotes expression
T1360 3517-3519 IN denotes of
T1361 3520-3524 NN denotes MGMT
T1362 3525-3527 CC denotes or
T1363 3528-3532 NN denotes loss
T1364 3533-3535 IN denotes of
T1365 3536-3539 NN denotes MMR
T1366 3540-3551 VB denotes contributes
T1367 3552-3565 RB denotes significantly
T1368 3566-3568 TO denotes to
T1369 3569-3572 NN denotes TMZ
T1370 3573-3583 NN denotes resistance
T1371 3584-3586 IN denotes in
T1372 3587-3591 JJ denotes many
T1373 3592-3600 JJ denotes clinical
T1374 3601-3606 NN denotes cases
T1375 3607-3608 -LRB- denotes (
T1376 3608-3615 NNP denotes Pollack
T1377 3616-3618 FW denotes et
T1378 3619-3622 FW denotes al.
T1379 3622-3623 -COMMA- denotes ,
T1380 3624-3628 CD denotes 2006
T1381 3628-3629 -COLON- denotes ;
T1382 3630-3634 NNP denotes Hegi
T1383 3635-3637 FW denotes et
T1384 3638-3641 FW denotes al.
T1385 3641-3642 -COMMA- denotes ,
T1386 3643-3647 CD denotes 2008
T1387 3647-3648 -COLON- denotes ;
T1388 3649-3657 NNP denotes Sarkaria
T1389 3658-3660 FW denotes et
T1390 3661-3664 FW denotes al.
T1391 3664-3665 -COMMA- denotes ,
T1392 3666-3670 CD denotes 2008
T1393 3670-3671 -RRB- denotes )
T1394 3673-3676 DT denotes The
T1395 3677-3687 NN denotes initiation
T1396 3688-3690 IN denotes of
T1397 3691-3700 JJ denotes apoptotic
T1398 3701-3710 NN denotes signaling
T1399 3711-3716 VB denotes fails
T1400 3717-3719 IN denotes in
T1401 3720-3723 DT denotes the
T1402 3724-3731 NN denotes absence
T1403 3732-3734 IN denotes of
T1404 3735-3738 DT denotes the
T1405 3739-3742 NN denotes MMR
T1406 3743-3749 NN denotes system
T1407 3751-3762 NN denotes Sensitivity
T1408 3763-3765 TO denotes to
T1409 3766-3769 NN denotes TMZ
T1410 3770-3772 VB denotes is
T1411 3773-3786 RB denotes significantly
T1412 3787-3797 VB denotes associated
T1413 3798-3802 IN denotes with
T1414 3803-3806 DT denotes the
T1415 3807-3818 NN denotes methylation
T1416 3819-3825 NN denotes status
T1417 3826-3828 IN denotes of
T1418 3829-3833 NN denotes MGMT
T1419 3834-3838 NN denotes gene
T1420 3839-3847 NN denotes promoter
T1421 3848-3850 IN denotes in
T1422 3851-3856 NN denotes cells
T1423 3857-3866 VB denotes committed
T1424 3867-3869 TO denotes to
T1425 3870-3885 NN denotes differentiation
T1426 3886-3887 -LRB- denotes (
T1427 3887-3895 FW denotes Villalva
T1428 3896-3898 FW denotes et
T1429 3899-3902 FW denotes al.
T1430 3902-3903 -COMMA- denotes ,
T1431 3904-3908 CD denotes 2012
T1432 3908-3909 -RRB- denotes )
T1433 3911-3913 DT denotes An
T1434 3914-3922 NN denotes increase
T1435 3923-3925 IN denotes in
T1436 3926-3930 NN denotes MGMT
T1437 3931-3935 NN denotes gene
T1438 3936-3944 NN denotes promoter
T1439 3945-3956 NN denotes methylation
T1440 3956-3957 -COMMA- denotes ,
T1441 3958-3963 WDT denotes which
T1442 3964-3970 VB denotes blocks
T1443 3971-3975 NN denotes MGMT
T1444 3976-3983 NN denotes protein
T1445 3984-3994 NN denotes expression
T1446 3994-3995 -COMMA- denotes ,
T1447 3996-4004 VB denotes prolongs
T1448 4005-4011 NN denotes cancer
T1449 4012-4019 NN denotes patient
T1450 4020-4028 NN denotes survival
T1451 4030-4042 RB denotes Intriguingly
T1452 4042-4043 -COMMA- denotes ,
T1453 4044-4057 VB denotes overexpressed
T1454 4058-4069 NN denotes microRNA-21
T1455 4070-4077 VB denotes reduces
T1456 4078-4087 NN denotes Bax/Bcl-2
T1457 4088-4093 NN denotes ratio
T1458 4094-4097 CC denotes and
T1459 4098-4107 NN denotes caspase-3
T1460 4108-4116 NN denotes activity
T1461 4116-4117 -COMMA- denotes ,
T1462 4118-4125 RB denotes thereby
T1463 4126-4134 VB denotes blocking
T1464 4135-4146 JJ denotes TMZ-induced
T1465 4147-4156 NN denotes apoptosis
T1466 4157-4158 -LRB- denotes (
T1467 4158-4161 NNP denotes Shi
T1468 4162-4164 FW denotes et
T1469 4165-4168 FW denotes al.
T1470 4168-4169 -COMMA- denotes ,
T1471 4170-4174 CD denotes 2010
T1472 4174-4175 -RRB- denotes )
T1473 4177-4188 NN denotes MicroRNA-21
T1474 4189-4191 VB denotes is
T1475 4192-4202 VB denotes considered
T1476 4203-4205 IN denotes as
T1477 4206-4207 DT denotes a
T1478 4208-4220 JJ denotes pro-survival
T1479 4221-4227 NN denotes factor
T1480 4228-4231 IN denotes for
T1481 4232-4238 NN denotes cancer
T1482 4239-4244 NN denotes cells
T1483 4245-4246 -LRB- denotes (
T1484 4246-4248 NNP denotes Li
T1485 4249-4251 FW denotes et
T1486 4252-4255 FW denotes al.
T1487 4255-4256 -COMMA- denotes ,
T1488 4257-4261 CD denotes 2012
T1489 4261-4262 -RRB- denotes )
T1490 4264-4273 NN denotes Integrins
T1491 4274-4278 VB denotes play
T1492 4279-4280 DT denotes a
T1493 4281-4285 NN denotes role
T1494 4286-4288 IN denotes in
T1495 4289-4292 DT denotes the
T1496 4293-4303 NN denotes resistance
T1497 4304-4306 IN denotes of
T1498 4307-4315 JJ denotes advanced
T1499 4316-4323 NN denotes cancers
T1500 4324-4326 TO denotes to
T1501 4327-4339 NN denotes radiotherapy
T1502 4340-4343 CC denotes and
T1503 4344-4357 NN denotes chemotherapy.
T1504 4358-4362 NN denotes α5β1
T1505 4363-4371 NN denotes integrin
T1506 4372-4382 RB denotes negatively
T1507 4383-4392 VB denotes regulates
T1508 4393-4396 NN denotes p53
T1509 4397-4406 NN denotes signaling
T1510 4406-4407 -COMMA- denotes ,
T1511 4408-4411 CC denotes and
T1512 4412-4415 DT denotes the
T1513 4416-4421 NN denotes event
T1514 4422-4429 VB denotes induces
T1515 4430-4436 NN denotes glioma
T1516 4437-4441 NN denotes cell
T1517 4442-4452 NN denotes resistance
T1518 4453-4455 TO denotes to
T1519 4456-4459 NN denotes TMZ
T1520 4460-4461 -LRB- denotes (
T1521 4461-4471 NNP denotes Janouskova
T1522 4472-4474 FW denotes et
T1523 4475-4478 FW denotes al.
T1524 4478-4479 -COMMA- denotes ,
T1525 4480-4484 CD denotes 2012
T1526 4484-4485 -RRB- denotes )
T1527 4485-4489 CD denotes . α5
T1528 4489-4497 NN denotes β1 integ
T1529 4497-4499 VB denotes ri
T1530 4499-4509 VB denotes n is consi
T1531 4509-4511 IN denotes de
T1532 4511-4512 DT denotes r
T1533 4512-4523 JJ denotes ed as a the
T1534 4523-4529 NN denotes rapeut
T1535 4529-4532 IN denotes ic
T1536 4532-4542 JJ denotes target for
T1537 4543-4548 NN denotes high-
T1538 4548-4554 NN denotes grade
T1539 4568-4571 DT denotes The
T1540 4572-4576 NN denotes base
T1541 4577-4585 NN denotes excision
T1542 4586-4592 NN denotes repair
T1543 4593-4599 NN denotes enzyme
T1544 4600-4629 NN denotes alkylpurine-DNA-N-glycosylase
T1545 4630-4631 -LRB- denotes (
T1546 4631-4635 NN denotes APNG
T1547 4635-4636 -RRB- denotes )
T1548 4636-4637 -COMMA- denotes ,
T1549 4638-4643 WDT denotes which
T1550 4644-4651 VB denotes repairs
T1551 4652-4655 DT denotes the
T1552 4656-4665 JJ denotes cytotoxic
T1553 4666-4673 NN denotes lesions
T1554 4674-4690 NN denotes N3-methyladenine
T1555 4691-4694 CC denotes and
T1556 4695-4711 NN denotes N7-methylguanine
T1557 4711-4712 -COMMA- denotes ,
T1558 4713-4717 RB denotes also
T1559 4718-4730 VB denotes participates
T1560 4731-4733 IN denotes in
T1561 4734-4737 DT denotes the
T1562 4738-4741 NN denotes TMZ
T1563 4742-4752 NN denotes resistance
T1564 4753-4754 -LRB- denotes (
T1565 4754-4763 NNP denotes Agnihotri
T1566 4764-4766 FW denotes et
T1567 4767-4770 FW denotes al.
T1568 4770-4771 -COMMA- denotes ,
T1569 4772-4776 CD denotes 2012
T1570 4776-4777 -RRB- denotes )
T1571 4779-4791 NN denotes Upregulation
T1572 4792-4794 IN denotes of
T1573 4795-4808 JJ denotes mitochondrial
T1574 4809-4820 JJ denotes respiratory
T1575 4821-4826 NN denotes chain
T1576 4827-4835 NN denotes coupling
T1577 4836-4838 TO denotes to
T1578 4839-4847 VB denotes suppress
T1579 4848-4851 DT denotes the
T1580 4852-4862 NN denotes production
T1581 4863-4865 IN denotes of
T1582 4866-4874 JJ denotes reactive
T1583 4875-4881 NN denotes oxygen
T1584 4882-4889 NN denotes species
T1585 4890-4891 -LRB- denotes (
T1586 4891-4894 NN denotes ROS
T1587 4894-4895 -RRB- denotes )
T1588 4896-4905 VB denotes regulated
T1589 4906-4908 IN denotes by
T1590 4909-4919 NN denotes cytochrome
T1591 4920-4921 NN denotes c
T1592 4922-4929 NN denotes oxidase
T1593 4930-4941 VB denotes contributes
T1594 4942-4944 IN denotes in
T1595 4945-4949 NN denotes part
T1596 4950-4952 TO denotes to
T1597 4953-4956 NN denotes TMZ
T1598 4957-4967 NN denotes resistance
T1599 4968-4970 IN denotes in
T1600 4971-4978 NN denotes gliomas
T1601 4979-4980 -LRB- denotes (
T1602 4980-4985 NNP denotes Oliva
T1603 4986-4988 FW denotes et
T1604 4989-4992 FW denotes al.
T1605 4992-4993 -COMMA- denotes ,
T1606 4994-4998 CD denotes 2011
T1607 4998-4999 -RRB- denotes )
T1608 5001-5009 NN denotes Reversal
T1609 5010-5012 IN denotes of
T1610 5013-5016 NN denotes TMZ
T1611 5017-5027 NN denotes resistance
T1612 5028-5031 MD denotes may
T1613 5032-5034 VB denotes be
T1614 5035-5043 VB denotes achieved
T1615 5044-5046 IN denotes by
T1616 5047-5051 NN denotes MGMT
T1617 5052-5068 NN denotes pseudosubstrates
T1618 5068-5069 -COMMA- denotes ,
T1619 5070-5086 NN denotes O6-benzylguanine
T1620 5087-5090 CC denotes and
T1621 5091-5102 NN denotes lomeguatrib
T1622 5103-5105 TO denotes to
T1623 5106-5115 VB denotes sensitize
T1624 5116-5122 NN denotes tumors
T1625 5123-5125 TO denotes to
T1626 5126-5129 NN denotes TMZ
T1627 5130-5131 -LRB- denotes (
T1628 5131-5136 NNP denotes Zhang
T1629 5137-5139 FW denotes et
T1630 5140-5143 FW denotes al.
T1631 5143-5144 -COMMA- denotes ,
T1632 5145-5150 NN denotes 2012b
T1633 5150-5151 -RRB- denotes )
T1634 5153-5173 NN denotes Methoxyamine-blocker
T1635 5174-5176 IN denotes of
T1636 5177-5181 NN denotes base
T1637 5182-5190 NN denotes excision
T1638 5191-5197 NN denotes repair
T1639 5198-5209 VB denotes contributes
T1640 5210-5223 RB denotes significantly
T1641 5224-5226 TO denotes to
T1642 5227-5230 NN denotes TMZ
T1643 5231-5243 NN denotes cytotoxicity
T1644 5244-5256 RB denotes particularly
T1645 5257-5261 WRB denotes when
T1646 5262-5278 NN denotes O6-methylguanine
T1647 5279-5286 NN denotes adducts
T1648 5287-5290 VB denotes are
T1649 5291-5299 VB denotes repaired
T1650 5300-5302 CC denotes or
T1651 5303-5312 VB denotes tolerated
T1652 5313-5314 -LRB- denotes (
T1653 5314-5322 NNP denotes Goellner
T1654 5323-5325 FW denotes et
T1655 5326-5329 FW denotes al.
T1656 5329-5330 -COMMA- denotes ,
T1657 5331-5335 CD denotes 2011
T1658 5335-5336 -COLON- denotes ;
T1659 5337-5342 NNP denotes Zhang
T1660 5343-5345 FW denotes et
T1661 5346-5349 FW denotes al.
T1662 5349-5350 -COMMA- denotes ,
T1663 5351-5356 NN denotes 2012b
T1664 5356-5357 -RRB- denotes )
T1665 5359-5363 JJ denotes Dual
T1666 5364-5373 NN denotes targeting
T1667 5374-5376 IN denotes of
T1668 5377-5381 NN denotes base
T1669 5382-5390 NN denotes excision
T1670 5391-5397 NN denotes repair
T1671 5398-5401 CC denotes and
T1672 5402-5405 NN denotes NAD
T1673 5405-5406 -LRB- denotes (
T1674 5406-5407 SYM denotes +
T1675 5407-5408 -RRB- denotes )
T1676 5409-5421 NN denotes biosynthesis
T1677 5422-5425 MD denotes may
T1678 5426-5433 VB denotes reverse
T1679 5434-5437 NN denotes TMZ
T1680 5438-5448 NN denotes resistance
T1681 5449-5451 IN denotes in
T1682 5452-5460 NN denotes patients
T1683 5461-5465 IN denotes with
T1684 5466-5475 JJ denotes resistant
T1685 5476-5479 CC denotes and
T1686 5480-5489 JJ denotes recurrent
T1687 5490-5493 NN denotes GBM
T1688 5494-5495 -LRB- denotes (
T1689 5495-5503 NNP denotes Goellner
T1690 5504-5506 FW denotes et
T1691 5507-5510 FW denotes al.
T1692 5510-5511 -COMMA- denotes ,
T1693 5512-5516 CD denotes 2011
T1694 5516-5517 -RRB- denotes )
T1695 5519-5531 NN denotes Interferon-β
T1696 5532-5533 -LRB- denotes (
T1697 5533-5538 NN denotes IFN-β
T1698 5538-5539 -RRB- denotes )
T1699 5539-5540 -COMMA- denotes ,
T1700 5541-5554 NN denotes levetiracetam
T1701 5555-5556 -LRB- denotes (
T1702 5556-5559 NN denotes LEV
T1703 5559-5560 -RRB- denotes )
T1704 5560-5561 -COMMA- denotes ,
T1705 5562-5573 NN denotes resveratrol
T1706 5573-5574 -COMMA- denotes ,
T1707 5575-5578 CC denotes and
T1708 5579-5587 JJ denotes valproic
T1709 5588-5592 NN denotes acid
T1710 5593-5594 -LRB- denotes (
T1711 5594-5597 NN denotes VAP
T1712 5597-5598 -RRB- denotes )
T1713 5599-5607 VB denotes increase
T1714 5608-5611 DT denotes the
T1715 5612-5623 NN denotes sensitivity
T1716 5624-5626 IN denotes of
T1717 5627-5630 NN denotes TMZ
T1718 5631-5638 IN denotes through
T1719 5639-5653 JJ denotes MGMT-dependent
T1720 5654-5656 CC denotes or
T1721 5657-5669 JJ denotes -independent
T1722 5670-5680 NN denotes mechanisms
T1723 5681-5682 -LRB- denotes (
T1724 5682-5688 NNP denotes Nakada
T1725 5689-5691 FW denotes et
T1726 5692-5695 FW denotes al.
T1727 5695-5696 -COMMA- denotes ,
T1728 5697-5701 CD denotes 2012
T1729 5701-5702 -RRB- denotes )
T1730 5704-5715 NN denotes Resveratrol
T1731 5715-5716 -COMMA- denotes ,
T1732 5717-5718 DT denotes a
T1733 5719-5726 JJ denotes natural
T1734 5727-5737 NN denotes polyphenol
T1735 5737-5738 -COMMA- denotes ,
T1736 5739-5747 VB denotes reverses
T1737 5748-5751 NN denotes TMZ
T1738 5752-5762 NN denotes resistance
T1739 5763-5766 IN denotes via
T1740 5767-5769 DT denotes an
T1741 5770-5785 JJ denotes NF-κB-dependent
T1742 5786-5795 NN denotes mechanism
T1743 5796-5797 -LRB- denotes (
T1744 5797-5802 NNP denotes Huang
T1745 5803-5805 FW denotes et
T1746 5806-5809 FW denotes al.
T1747 5809-5810 -COMMA- denotes ,
T1748 5811-5815 CD denotes 2012
T1749 5815-5816 -RRB- denotes )
T1750 5818-5823 NN denotes STAT3
T1751 5824-5833 NN denotes inhibitor
T1752 5834-5836 CC denotes or
T1753 5837-5842 NN denotes STAT3
T1754 5843-5852 NN denotes knockdown
T1755 5853-5864 VB denotes potentiates
T1756 5865-5868 NN denotes TMZ
T1757 5869-5877 NN denotes efficacy
T1758 5878-5880 IN denotes in
T1759 5881-5890 JJ denotes resistant
T1760 5891-5894 NN denotes GBM
T1761 5895-5899 NN denotes cell
T1762 5900-5905 NN denotes lines
T1763 5906-5907 -LRB- denotes (
T1764 5907-5914 NNP denotes Kohsaka
T1765 5915-5917 FW denotes et
T1766 5918-5921 FW denotes al.
T1767 5921-5922 -COMMA- denotes ,
T1768 5923-5927 CD denotes 2012
T1769 5927-5928 -RRB- denotes )
T1770 5930-5942 JJ denotes Intratumoral
T1771 5943-5950 NN denotes hypoxia
T1772 5951-5953 VB denotes is
T1773 5954-5960 JJ denotes common
T1774 5961-5963 IN denotes in
T1775 5964-5968 NN denotes GBMs
T1776 5969-5972 CC denotes and
T1777 5973-5976 MD denotes may
T1778 5977-5979 VB denotes be
T1779 5980-5990 VB denotes associated
T1780 5991-5995 IN denotes with
T1781 5996-5999 DT denotes the
T1782 6000-6011 NN denotes development
T1783 6012-6014 IN denotes of
T1784 6015-6018 NN denotes TMZ
T1785 6019-6029 NN denotes resistance
T1786 6031-6038 VB denotes Induced
T1787 6039-6048 NN denotes hyperoxia
T1788 6049-6052 MD denotes can
T1789 6053-6055 VB denotes be
T1790 6056-6064 VB denotes utilized
T1791 6065-6067 TO denotes to
T1792 6068-6075 VB denotes reverse
T1793 6076-6079 NN denotes TMZ
T1794 6080-6090 NN denotes resistance
T1795 6091-6093 IN denotes in
T1796 6094-6098 NN denotes GBMs
T1797 6099-6100 -LRB- denotes (
T1798 6100-6103 NNP denotes Sun
T1799 6104-6106 FW denotes et
T1800 6107-6110 FW denotes al.
T1801 6110-6111 -COMMA- denotes ,
T1802 6112-6116 CD denotes 2012
T1803 6116-6117 -RRB- denotes )
T1804 6119-6125 NN denotes Cancer
T1805 6126-6130 NN denotes stem
T1806 6131-6136 NN denotes cells
T1807 6137-6140 VB denotes are
T1808 6141-6149 RB denotes probably
T1809 6150-6153 DT denotes the
T1810 6154-6157 NN denotes key
T1811 6158-6160 TO denotes to
T1812 6161-6168 NN denotes failure
T1813 6169-6171 IN denotes in
T1814 6172-6175 NN denotes TMZ
T1815 6176-6185 NN denotes treatment
T1816 6187-6190 DT denotes The
T1817 6191-6198 NN denotes concept
T1818 6199-6201 IN denotes of
T1819 6202-6208 NN denotes cancer
T1820 6209-6213 NN denotes stem
T1821 6214-6218 NN denotes cell
T1822 6219-6227 NN denotes survival
T1823 6228-6232 IN denotes from
T1824 6233-6242 NN denotes treatment
T1825 6243-6247 IN denotes with
T1826 6248-6251 NN denotes TMZ
T1827 6252-6255 CC denotes and
T1828 6256-6261 JJ denotes other
T1829 6262-6278 JJ denotes chemotherapeutic
T1830 6279-6284 NN denotes drugs
T1831 6285-6288 VB denotes has
T1832 6289-6293 VB denotes been
T1833 6294-6298 RB denotes more
T1834 6299-6310 VB denotes complicated
T1835 6311-6315 IN denotes than
T1836 6316-6326 RB denotes previously
T1837 6327-6334 VB denotes thought
T1838 6335-6336 -LRB- denotes (
T1839 6336-6341 NNP denotes Beier
T1840 6342-6344 FW denotes et
T1841 6345-6348 FW denotes al.
T1842 6348-6349 -COMMA- denotes ,
T1843 6350-6354 CD denotes 2011
T1844 6354-6355 -COLON- denotes ;
T1845 6356-6360 NNP denotes Chen
T1846 6361-6363 FW denotes et
T1847 6364-6367 FW denotes al.
T1848 6367-6368 -COMMA- denotes ,
T1849 6369-6373 CD denotes 2012
T1850 6373-6374 -RRB- denotes )
T1851 6376-6390 JJ denotes CD133-positive
T1852 6391-6397 NN denotes cancer
T1853 6398-6402 NN denotes stem
T1854 6403-6408 NN denotes cells
T1855 6409-6412 VB denotes are
T1856 6413-6422 VB denotes expressed
T1857 6423-6425 IN denotes in
T1858 6426-6430 CC denotes both
T1859 6431-6437 JJ denotes normal
T1860 6438-6442 NN denotes stem
T1861 6443-6448 NN denotes cells
T1862 6449-6452 CC denotes and
T1863 6453-6459 NN denotes cancer
T1864 6460-6464 NN denotes stem
T1865 6465-6470 NN denotes cells
T1866 6471-6472 -LRB- denotes (
T1867 6472-6479 NNP denotes Donovan
T1868 6480-6483 CC denotes and
T1869 6484-6494 NNP denotes Pilkington
T1870 6494-6495 -COMMA- denotes ,
T1871 6496-6500 CD denotes 2012
T1872 6500-6501 -RRB- denotes )
T1873 6503-6510 RB denotes However
T1874 6510-6511 -COMMA- denotes ,
T1875 6512-6515 DT denotes the
T1876 6516-6520 NN denotes role
T1877 6521-6523 IN denotes of
T1878 6524-6529 NN denotes CD133
T1879 6530-6532 IN denotes as
T1880 6533-6534 DT denotes a
T1881 6535-6541 NN denotes marker
T1882 6542-6545 IN denotes for
T1883 6546-6552 NN denotes glioma
T1884 6553-6559 NN denotes cancer
T1885 6560-6564 NN denotes stem
T1886 6565-6570 NN denotes cells
T1887 6571-6579 JJ denotes relative
T1888 6580-6582 TO denotes to
T1889 6583-6586 PRP-DOLLAR- denotes its
T1890 6587-6597 JJ denotes biological
T1891 6598-6606 NN denotes function
T1892 6607-6610 VB denotes has
T1893 6611-6614 RB denotes yet
T1894 6615-6617 TO denotes to
T1895 6618-6620 VB denotes be
T1896 6621-6632 VB denotes established
T4147 6676-6684 RB denotes Recently
T4148 6684-6685 -COMMA- denotes ,
T4149 6686-6691 NN denotes tumor
T4150 6692-6703 NN denotes suppressors
T4151 6704-6707 NN denotes p53
T4152 6708-6711 CC denotes and
T4153 6712-6716 NN denotes WWOX
T4154 6717-6721 VB denotes were
T4155 6722-6727 VB denotes shown
T4156 6728-6730 TO denotes to
T4157 6731-6739 VB denotes regulate
T4158 6740-6743 DT denotes the
T4159 6744-6753 NN denotes apoptosis
T4160 6754-6756 IN denotes of
T4161 6757-6769 NN denotes glioblastoma
T4162 6770-6775 NN denotes cells
T4163 6776-6777 -LRB- denotes (
T4164 6777-6783 NNP denotes Chiang
T4165 6784-6786 FW denotes et
T4166 6787-6790 FW denotes al.
T4167 6790-6791 -COMMA- denotes ,
T4168 6792-6796 CD denotes 2012
T4169 6796-6797 -RRB- denotes )
T4170 6799-6801 JJ denotes WW
T4171 6802-6819 JJ denotes domain-containing
T4172 6820-6834 NN denotes oxidoreductase
T4173 6834-6835 -COMMA- denotes ,
T4174 6836-6841 VB denotes known
T4175 6842-6844 IN denotes as
T4176 6845-6849 NN denotes WWOX
T4177 6849-6850 -COMMA- denotes ,
T4178 6851-6854 NN denotes FOR
T4179 6854-6855 -COMMA- denotes ,
T4180 6856-6858 CC denotes or
T4181 6859-6863 NN denotes WOX1
T4182 6863-6864 -COMMA- denotes ,
T4183 6865-6867 VB denotes is
T4184 6868-6875 VB denotes encoded
T4185 6876-6878 IN denotes by
T4186 6879-6884 JJ denotes human
T4187 6885-6887 CC denotes or
T4188 6888-6893 NN denotes mouse
T4189 6894-6903 NN denotes WWOX/Wwox
T4190 6904-6908 NN denotes gene
T4191 6910-6914 DT denotes This
T4192 6915-6919 NN denotes gene
T4193 6920-6922 VB denotes is
T4194 6923-6930 JJ denotes located
T4195 6931-6933 IN denotes in
T4196 6934-6944 NN denotes chromosome
T4197 6945-6957 NN denotes 16q23.3–24.1
T4198 6957-6958 -COMMA- denotes ,
T4199 6959-6961 DT denotes an
T4200 6962-6966 NN denotes area
T4201 6967-6972 VB denotes known
T4202 6973-6975 IN denotes as
T4203 6976-6979 DT denotes the
T4204 6980-6986 JJ denotes common
T4205 6987-6994 JJ denotes fragile
T4206 6995-6999 NN denotes site
T4207 7000-7006 NN denotes FRA16D
T4208 7008-7011 DT denotes The
T4209 7012-7023 JJ denotes full-length
T4210 7024-7028 NN denotes WWOX
T4211 7029-7036 NN denotes protein
T4212 7037-7039 VB denotes is
T4213 7040-7048 VB denotes composed
T4214 7049-7051 IN denotes of
T4215 7052-7055 CD denotes two
T4216 7056-7066 JJ denotes N-terminal
T4217 7067-7069 NN denotes WW
T4218 7070-7077 NN denotes domains
T4219 7077-7078 -COMMA- denotes ,
T4220 7079-7080 DT denotes a
T4221 7081-7091 JJ denotes C-terminal
T4222 7092-7103 NN denotes short-chain
T4223 7104-7111 NN denotes alcohol
T4224 7112-7135 NN denotes dehydrogenase/reductase
T4225 7136-7137 -LRB- denotes (
T4226 7137-7140 NN denotes SDR
T4227 7140-7141 -RRB- denotes )
T4228 7142-7148 NN denotes domain
T4229 7148-7149 -COMMA- denotes ,
T4230 7150-7153 CC denotes and
T4231 7154-7155 DT denotes a
T4232 7156-7168 JJ denotes proapoptotic
T4233 7169-7179 JJ denotes C-terminal
T4234 7180-7184 NN denotes tail
T4235 7185-7187 NN denotes D3
T4236 7188-7189 -LRB- denotes (
T4237 7189-7194 NNP denotes Chang
T4238 7195-7197 FW denotes et
T4239 7198-7201 FW denotes al.
T4240 7201-7202 -COMMA- denotes ,
T4241 7203-7207 CD denotes 2001
T4242 7207-7208 -COMMA- denotes ,
T4243 7209-7213 CD denotes 2007
T4244 7213-7214 -COMMA- denotes ,
T4245 7215-7219 CD denotes 2010
T4246 7219-7220 -COLON- denotes ;
T4247 7221-7228 NNP denotes Aqeilan
T4248 7229-7231 FW denotes et
T4249 7232-7235 FW denotes al.
T4250 7235-7236 -COMMA- denotes ,
T4251 7237-7241 CD denotes 2004
T4252 7241-7242 -COMMA- denotes ,
T4253 7243-7247 CD denotes 2007
T4254 7247-7248 -COLON- denotes ;
T4255 7249-7253 NNP denotes Hong
T4256 7254-7256 FW denotes et
T4257 7257-7260 FW denotes al.
T4258 7260-7261 -COMMA- denotes ,
T4259 7262-7266 CD denotes 2007
T4260 7266-7267 -COLON- denotes ;
T4261 7268-7273 NNP denotes Salah
T4262 7274-7276 FW denotes et
T4263 7277-7280 FW denotes al.
T4264 7280-7281 -COMMA- denotes ,
T4265 7282-7286 CD denotes 2012
T4266 7286-7287 -RRB- denotes )
T4267 7288-7289 -LRB- denotes (
T4268 7289-7295 NN denotes Figure
T4269 7296-7297 CD denotes 1
T4270 7297-7298 -RRB- denotes )
T4271 7300-7304 NN denotes WWOX
T4272 7305-7308 MD denotes may
T4273 7309-7312 VB denotes act
T4274 7313-7315 IN denotes as
T4275 7316-7318 DT denotes an
T4276 7319-7330 JJ denotes alternative
T4277 7331-7339 NN denotes receptor
T4278 7340-7343 IN denotes for
T4279 7344-7347 NN denotes sex
T4280 7348-7355 NN denotes steroid
T4281 7356-7364 NN denotes hormones
T4282 7364-7365 -COMMA- denotes ,
T4283 7366-7371 IN denotes since
T4284 7372-7375 PRP-DOLLAR- denotes its
T4285 7376-7379 NN denotes SDR
T4286 7380-7386 NN denotes domain
T4287 7387-7396 VB denotes possesses
T4288 7397-7399 DT denotes an
T4289 7400-7404 NN denotes NSYK
T4290 7405-7410 NN denotes motif
T4291 7411-7418 JJ denotes capable
T4292 7419-7421 IN denotes of
T4293 7422-7433 VB denotes interacting
T4294 7434-7438 IN denotes with
T4295 7439-7447 NN denotes androgen
T4296 7448-7451 CC denotes and
T4297 7452-7460 NN denotes estrogen
T4298 7461-7462 -LRB- denotes (
T4299 7462-7467 NNP denotes Chang
T4300 7468-7470 FW denotes et
T4301 7471-7474 FW denotes al.
T4302 7474-7475 -COMMA- denotes ,
T4303 7476-7481 NN denotes 2005a
T4304 7481-7482 -COLON- denotes ;
T4305 7483-7485 NNP denotes Su
T4306 7486-7488 FW denotes et
T4307 7489-7492 FW denotes al.
T4308 7492-7493 -COMMA- denotes ,
T4309 7494-7498 CD denotes 2012
T4310 7498-7499 -RRB- denotes )
T13043 7511-7520 JJ denotes Schematic
T13044 7521-7529 NN denotes diagrams
T13045 7530-7532 IN denotes of
T13046 7533-7537 NN denotes WWOX
T13047 7538-7547 NN denotes structure
T13048 7548-7551 CC denotes and
T13049 7552-7555 PRP-DOLLAR- denotes its
T13050 7556-7560 NN denotes role
T13051 7561-7563 IN denotes in
T13052 7564-7573 NN denotes signaling
T13053 7575-7579 NN denotes WWOX
T13054 7580-7588 VB denotes contains
T13055 7589-7592 CD denotes two
T13056 7593-7603 JJ denotes N-terminal
T13057 7604-7606 NN denotes WW
T13058 7607-7614 NN denotes domains
T13059 7614-7615 -COMMA- denotes ,
T13060 7616-7617 DT denotes a
T13061 7618-7628 JJ denotes C-terminal
T13062 7629-7640 NN denotes short-chain
T13063 7641-7648 NN denotes alcohol
T13064 7649-7672 NN denotes dehydrogenase/reductase
T13065 7673-7674 -LRB- denotes (
T13066 7674-7677 NN denotes SDR
T13067 7677-7678 -RRB- denotes )
T13068 7679-7685 NN denotes domain
T13069 7685-7686 -COMMA- denotes ,
T13070 7687-7690 CC denotes and
T13071 7691-7692 DT denotes a
T13072 7693-7695 NN denotes D3
T13073 7696-7702 NN denotes region
T13074 7704-7705 DT denotes A
T13075 7706-7713 JJ denotes nuclear
T13076 7714-7726 NN denotes localization
T13077 7727-7733 NN denotes signal
T13078 7734-7735 -LRB- denotes (
T13079 7735-7738 NN denotes NLS
T13080 7738-7739 -RRB- denotes )
T13081 7740-7742 VB denotes is
T13082 7743-7745 IN denotes in
T13083 7746-7753 IN denotes between
T13084 7754-7757 DT denotes the
T13085 7758-7760 NNP denotes WW
T13086 7761-7768 NN denotes domains
T13087 7769-7770 -LRB- denotes (
T13088 7770-7775 NNP denotes Chang
T13089 7776-7778 FW denotes et
T13090 7779-7782 FW denotes al.
T13091 7782-7783 -COMMA- denotes ,
T13092 7784-7788 CD denotes 2003
T13093 7788-7789 -COMMA- denotes ,
T13094 7790-7794 CD denotes 2007
T13095 7794-7795 -COLON- denotes ;
T13096 7796-7799 NNP denotes Del
T13097 7800-7804 NNP denotes Mare
T13098 7805-7807 FW denotes et
T13099 7808-7811 FW denotes al.
T13100 7811-7812 -COMMA- denotes ,
T13101 7813-7817 CD denotes 2011
T13102 7817-7818 -COLON- denotes ;
T13103 7819-7824 NNP denotes Salah
T13104 7825-7827 FW denotes et
T13105 7828-7831 FW denotes al.
T13106 7831-7832 -COMMA- denotes ,
T13107 7833-7837 CD denotes 2012
T13108 7837-7838 -COLON- denotes ;
T13109 7839-7841 NNP denotes Su
T13110 7842-7844 FW denotes et
T13111 7845-7848 FW denotes al.
T13112 7848-7849 -COMMA- denotes ,
T13113 7850-7854 CD denotes 2012
T13114 7854-7855 -COLON- denotes ;
T13115 7856-7863 NN denotes reviews
T13116 7863-7864 -RRB- denotes )
T13117 7866-7869 DT denotes The
T13118 7870-7873 NN denotes SDR
T13119 7874-7880 NN denotes domain
T13120 7881-7890 VB denotes possesses
T13121 7891-7892 DT denotes a
T13122 7893-7913 JJ denotes mitochondria-binding
T13123 7914-7920 NN denotes region
T13124 7922-7927 EX denotes There
T13125 7928-7931 VB denotes are
T13126 7932-7935 CD denotes two
T13127 7936-7945 VB denotes conserved
T13128 7946-7954 NN denotes tyrosine
T13129 7955-7970 NN denotes phosphorylation
T13130 7971-7976 NN denotes sites
T13131 7976-7977 -COMMA- denotes ,
T13132 7978-7983 NN denotes Tyr33
T13133 7984-7987 CC denotes and
T13134 7988-7994 NN denotes Tyr287
T13135 7996-8001 JJ denotes Other
T13136 8002-8017 NN denotes phosphorylation
T13137 8018-8023 NN denotes sites
T13138 8024-8033 VB denotes predicted
T13139 8034-8036 IN denotes by
T13140 8037-8044 NNP denotes NetPhos
T13141 8045-8048 CD denotes 2.0
T13142 8049-8055 NNP denotes Server
T13143 8056-8059 VB denotes are
T13144 8060-8064 NN denotes Tyr6
T13145 8064-8065 -COMMA- denotes ,
T13146 8066-8071 NN denotes Thr12
T13147 8071-8072 -COMMA- denotes ,
T13148 8073-8078 NN denotes Ser14
T13149 8078-8079 -COMMA- denotes ,
T13150 8080-8085 NN denotes Tyr61
T13151 8085-8086 -COMMA- denotes ,
T13152 8087-8093 NN denotes Tyr293
T13153 8093-8094 -COMMA- denotes ,
T13154 8095-8098 CC denotes and
T13155 8099-8105 NN denotes Thr3B3
T13156 8105-8106 -COMMA- denotes ,
T13157 8107-8119 RB denotes respectively
T13158 8121-8125 IN denotes Upon
T13159 8126-8132 NN denotes stress
T13160 8133-8144 NN denotes stimulation
T13161 8144-8145 -COMMA- denotes ,
T13162 8146-8150 NN denotes WWOX
T13163 8151-8153 VB denotes is
T13164 8154-8168 VB denotes phosphorylated
T13165 8169-8171 IN denotes in
T13166 8172-8177 NN denotes Tyr33
T13167 8178-8181 CC denotes and
T13168 8182-8187 VB denotes binds
T13169 8188-8191 NN denotes p53
T13170 8193-8196 DT denotes The
T13171 8197-8205 NN denotes WWOX/p53
T13172 8206-8213 NN denotes complex
T13173 8214-8218 RB denotes then
T13174 8219-8231 VB denotes translocates
T13175 8232-8234 TO denotes to
T13176 8235-8247 NN denotes mitochondria
T13177 8248-8250 CC denotes or
T13178 8251-8258 NN denotes nucleus
T13179 8259-8261 TO denotes to
T13180 8262-8268 VB denotes induce
T13181 8269-8278 NN denotes apoptosis
T13182 8280-8284 NN denotes WWOX
T13183 8285-8289 RB denotes also
T13184 8290-8295 VB denotes binds
T13185 8296-8300 NN denotes PPxY
T13186 8301-8317 JJ denotes motif-containing
T13187 8318-8331 NN denotes transcription
T13188 8332-8339 NN denotes factors
T13189 8339-8340 -COMMA- denotes ,
T13190 8341-8345 JJ denotes such
T13191 8346-8348 IN denotes as
T13192 8349-8354 NN denotes RUNX2
T13193 8354-8355 -COMMA- denotes ,
T13194 8356-8361 NN denotes c-Jun
T13195 8361-8362 -COMMA- denotes ,
T13196 8363-8366 CC denotes and
T13197 8367-8372 NN denotes ERBB4
T13198 8372-8373 -COMMA- denotes ,
T13199 8374-8377 IN denotes via
T13200 8378-8381 PRP-DOLLAR- denotes its
T13201 8382-8387 JJ denotes first
T13202 8388-8390 NNP denotes WW
T13203 8391-8397 NN denotes domain
T13204 8397-8398 -COMMA- denotes ,
T13205 8399-8402 CC denotes and
T13206 8403-8406 DT denotes the
T13207 8407-8414 NN denotes binding
T13208 8415-8421 VB denotes blocks
T13209 8422-8425 DT denotes the
T13210 8426-8434 NN denotes activity
T13211 8435-8437 IN denotes of
T13212 8438-8443 DT denotes these
T13213 8444-8452 NN denotes proteins
T13214 8453-8455 IN denotes by
T13215 8456-8465 VB denotes retaining
T13216 8466-8470 PRP denotes them
T13217 8471-8473 IN denotes in
T13218 8474-8477 DT denotes the
T13219 8478-8487 NN denotes cytoplasm
T13220 8489-8493 NN denotes WWOX
T13221 8494-8499 VB denotes binds
T13222 8500-8503 NNP denotes Tau
T13223 8504-8507 IN denotes via
T13224 8508-8511 PRP-DOLLAR- denotes its
T13225 8512-8515 NN denotes SDR
T13226 8516-8522 NN denotes domain
T13227 8524-8528 NN denotes WWOX
T13228 8529-8541 VB denotes participates
T13229 8542-8544 IN denotes in
T13230 8545-8548 DT denotes the
T13231 8549-8562 NN denotes Wnt/β-catenin
T13232 8563-8569 NN denotes signal
T13233 8570-8577 NN denotes pathway
T13234 8578-8580 IN denotes by
T13235 8581-8588 VB denotes binding
T13236 8589-8592 NN denotes Dvl
T13237 8593-8596 CC denotes and
T13238 8597-8607 VB denotes inhibiting
T13239 8608-8611 PRP-DOLLAR- denotes its
T13240 8612-8619 JJ denotes nuclear
T13241 8620-8626 NN denotes import
T13242 8628-8635 NN denotes Phorbol
T13243 8636-8641 NN denotes ester
T13244 8642-8652 VB denotes stimulates
T13245 8653-8656 DT denotes the
T13246 8657-8669 NN denotes dissociation
T13247 8670-8672 IN denotes of
T13248 8673-8681 NN denotes MEK/WWOX
T13249 8682-8689 NN denotes complex
T13250 8690-8692 IN denotes in
T13251 8693-8699 NN denotes Jurkat
T13252 8700-8701 NN denotes T
T13253 8702-8706 NN denotes cell
T13254 8706-8707 -COMMA- denotes ,
T13255 8708-8711 CC denotes and
T13256 8712-8715 DT denotes the
T13257 8716-8724 VB denotes released
T13258 8725-8729 NN denotes WWOX
T13259 8730-8742 VB denotes translocates
T13260 8743-8745 TO denotes to
T13261 8746-8749 DT denotes the
T13262 8750-8762 NN denotes mitochondria
T13263 8763-8766 IN denotes for
T13264 8767-8774 VB denotes causing
T13265 8775-8779 NN denotes cell
T13266 8780-8785 NN denotes death
T13267 8787-8791 NN denotes WWOX
T13268 8792-8794 VB denotes is
T13269 8795-8804 VB denotes recruited
T13270 8805-8807 TO denotes to
T13271 8808-8811 DT denotes the
T13272 8812-8820 NN denotes membrane
T13273 8821-8825 NN denotes area
T13274 8826-8828 IN denotes by
T13275 8829-8840 NN denotes association
T13276 8841-8845 IN denotes with
T13277 8846-8852 NN denotes Hyal-2
T13278 8853-8856 CC denotes and
T13279 8857-8871 JJ denotes phospho-Ezrin.
T13280 8872-8878 NN denotes Hyal-2
T13281 8879-8881 VB denotes is
T13282 8882-8884 DT denotes an
T13283 8885-8896 JJ denotes alternative
T13284 8897-8905 NN denotes receptor
T13285 8906-8909 IN denotes for
T13286 8910-8916 NN denotes TGF-β1
T13287 8918-8920 IN denotes In
T13288 8921-8929 NN denotes response
T13289 8930-8932 TO denotes to
T13290 8933-8939 NN denotes TGF-β1
T13291 8939-8940 -COMMA- denotes ,
T13292 8941-8945 NN denotes WWOX
T13293 8946-8951 VB denotes binds
T13294 8952-8958 NN denotes Hyal-2
T13295 8959-8962 CC denotes and
T13296 8963-8968 VB denotes forms
T13297 8969-8970 DT denotes a
T13298 8971-8978 NN denotes complex
T13299 8978-8979 -COMMA- denotes ,
T13300 8980-8988 VB denotes followed
T13301 8989-8991 IN denotes by
T13302 8992-9002 VB denotes relocating
T13303 9003-9005 TO denotes to
T13304 9006-9009 DT denotes the
T13305 9010-9017 NN denotes nucleus
T13306 9018-9021 CC denotes and
T13307 9022-9031 VB denotes enhancing
T13308 9032-9035 DT denotes the
T13309 9036-9047 JJ denotes SMAD-driven
T13310 9048-9056 NN denotes promoter
T13311 9057-9065 NN denotes activity
T13312 9067-9071 NN denotes Ack1
T13313 9071-9072 -COMMA- denotes ,
T13314 9073-9082 VB denotes activated
T13315 9083-9099 JJ denotes Cdc42-associated
T13316 9100-9106 NN denotes kinase
T13317 9107-9108 CD denotes 1
T13318 9108-9109 -COLON- denotes ;
T13319 9110-9116 NN denotes Hyal-2
T13320 9116-9117 -COMMA- denotes ,
T13321 9118-9142 NN denotes hyaluronoglucosaminidase
T13322 9143-9144 CD denotes 2
T13323 9144-9145 -COLON- denotes ;
T13324 9146-9149 NN denotes CKI
T13325 9149-9150 -COMMA- denotes ,
T13326 9151-9157 NN denotes casein
T13327 9158-9164 NN denotes kinase
T13328 9164-9165 -COLON- denotes ;
T13329 9166-9169 NN denotes GSK
T13330 9169-9170 -COMMA- denotes ,
T13331 9171-9179 NN denotes glycogen
T13332 9180-9188 NN denotes synthase
T13333 9189-9195 NN denotes kinase
T13334 9195-9196 -COLON- denotes ;
T13335 9197-9200 NN denotes PKA
T13336 9200-9201 -COMMA- denotes ,
T13337 9202-9209 NN denotes protein
T13338 9210-9216 NN denotes kinase
T13339 9217-9218 NN denotes A
T4311 9220-9230 NN denotes Expression
T4312 9231-9233 IN denotes of
T4313 9234-9238 NN denotes WWOX
T4314 9239-9241 VB denotes is
T4315 9242-9248 CC denotes either
T4316 9249-9256 VB denotes altered
T4317 9257-9259 CC denotes or
T4318 9260-9264 VB denotes lost
T4319 9265-9269 IN denotes from
T4320 9270-9280 JJ denotes epigenetic
T4321 9281-9293 NN denotes modification
T4322 9294-9296 IN denotes in
T4323 9297-9305 JJ denotes multiple
T4324 9306-9315 JJ denotes malignant
T4325 9316-9323 NN denotes cancers
T4326 9323-9324 -COMMA- denotes ,
T4327 9325-9329 JJ denotes such
T4328 9330-9332 IN denotes as
T4329 9333-9342 JJ denotes non-small
T4330 9343-9347 NN denotes cell
T4331 9348-9352 NN denotes lung
T4332 9353-9362 NN denotes carcinoma
T4333 9363-9364 -LRB- denotes (
T4334 9364-9370 NNP denotes Donati
T4335 9371-9373 FW denotes et
T4336 9374-9377 FW denotes al.
T4337 9377-9378 -COMMA- denotes ,
T4338 9379-9383 CD denotes 2007
T4339 9383-9384 -RRB- denotes )
T4340 9384-9385 -COMMA- denotes ,
T4341 9386-9399 JJ denotes hematopoietic
T4342 9400-9412 NN denotes malignancies
T4343 9413-9414 -LRB- denotes (
T4344 9414-9419 NNP denotes Ishii
T4345 9420-9423 CC denotes and
T4346 9424-9432 NNP denotes Furukawa
T4347 9432-9433 -COMMA- denotes ,
T4348 9434-9438 CD denotes 2004
T4349 9438-9439 -RRB- denotes )
T4350 9439-9440 -COMMA- denotes ,
T4351 9441-9448 JJ denotes gastric
T4352 9449-9458 NN denotes carcinoma
T4353 9459-9460 -LRB- denotes (
T4354 9460-9467 NNP denotes Aqeilan
T4355 9468-9470 FW denotes et
T4356 9471-9474 FW denotes al.
T4357 9474-9475 -COMMA- denotes ,
T4358 9476-9480 CD denotes 2004
T4359 9480-9481 -RRB- denotes )
T4360 9481-9482 -COMMA- denotes ,
T4361 9483-9493 JJ denotes pancreatic
T4362 9494-9503 NN denotes carcinoma
T4363 9504-9505 -LRB- denotes (
T4364 9505-9511 NNP denotes Kuroki
T4365 9512-9514 FW denotes et
T4366 9515-9518 FW denotes al.
T4367 9518-9519 -COMMA- denotes ,
T4368 9520-9524 CD denotes 2004
T4369 9524-9525 -RRB- denotes )
T4370 9525-9526 -COMMA- denotes ,
T4371 9527-9533 NN denotes breast
T4372 9534-9543 NN denotes carcinoma
T4373 9544-9545 -LRB- denotes (
T4374 9545-9550 NNP denotes Guler
T4375 9551-9553 FW denotes et
T4376 9554-9557 FW denotes al.
T4377 9557-9558 -COMMA- denotes ,
T4378 9559-9563 CD denotes 2004
T4379 9563-9564 -COLON- denotes ;
T4380 9565-9572 NNP denotes Aqeilan
T4381 9573-9575 FW denotes et
T4382 9576-9579 FW denotes al.
T4383 9579-9580 -COMMA- denotes ,
T4384 9581-9585 CD denotes 2007
T4385 9585-9586 -RRB- denotes )
T4386 9586-9587 -COMMA- denotes ,
T4387 9588-9591 CC denotes and
T4388 9592-9604 NN denotes glioblastoma
T4389 9605-9615 JJ denotes multiforme
T4390 9616-9617 -LRB- denotes (
T4391 9617-9622 NNP denotes Kosla
T4392 9623-9625 FW denotes et
T4393 9626-9629 FW denotes al.
T4394 9629-9630 -COMMA- denotes ,
T4395 9631-9635 CD denotes 2011
T4396 9635-9636 -RRB- denotes )
T4397 9638-9649 NN denotes Restoration
T4398 9650-9652 IN denotes of
T4399 9653-9657 NN denotes WWOX
T4400 9658-9662 NN denotes gene
T4401 9663-9671 VB denotes prevents
T4402 9672-9675 DT denotes the
T4403 9676-9682 NN denotes growth
T4404 9683-9685 IN denotes of
T4405 9686-9690 NN denotes lung
T4406 9691-9697 NN denotes cancer
T4407 9698-9699 -LRB- denotes (
T4408 9699-9705 NNP denotes Fabbri
T4409 9706-9708 FW denotes et
T4410 9709-9712 FW denotes al.
T4411 9712-9713 -COMMA- denotes ,
T4412 9714-9718 CD denotes 2005
T4413 9718-9719 -RRB- denotes )
T4414 9719-9720 -COMMA- denotes ,
T4415 9721-9731 JJ denotes pancreatic
T4416 9732-9738 NN denotes cancer
T4417 9739-9740 -LRB- denotes (
T4418 9740-9748 NNP denotes Nakayama
T4419 9749-9751 FW denotes et
T4420 9752-9755 FW denotes al.
T4421 9755-9756 -COMMA- denotes ,
T4422 9757-9761 CD denotes 2008
T4423 9761-9762 -RRB- denotes )
T4424 9762-9763 -COMMA- denotes ,
T4425 9764-9767 CC denotes and
T4426 9768-9776 NN denotes prostate
T4427 9777-9783 NN denotes cancer
T4428 9784-9785 -LRB- denotes (
T4429 9785-9789 NNP denotes Hong
T4430 9790-9792 FW denotes et
T4431 9793-9796 FW denotes al.
T4432 9796-9797 -COMMA- denotes ,
T4433 9798-9802 CD denotes 2009
T4434 9802-9803 -RRB- denotes )
T4435 9805-9808 DT denotes The
T4436 9809-9814 JJ denotes first
T4437 9815-9817 NN denotes WW
T4438 9818-9824 NN denotes domain
T4439 9825-9827 IN denotes of
T4440 9828-9832 NN denotes WWOX
T4441 9833-9836 MD denotes may
T4442 9837-9845 VB denotes interact
T4443 9846-9850 IN denotes with
T4444 9851-9859 NN denotes proteins
T4445 9860-9870 VB denotes possessing
T4446 9871-9872 DT denotes a
T4447 9873-9877 NN denotes PPxY
T4448 9878-9883 NN denotes motif
T4449 9883-9884 -LRB- denotes (
T4450 9884-9885 NN denotes s
T4451 9885-9886 -RRB- denotes )
T4452 9887-9891 JJ denotes such
T4453 9892-9894 IN denotes as
T4454 9895-9900 NN denotes AP-2γ
T4455 9900-9901 -COMMA- denotes ,
T4456 9902-9905 NN denotes p73
T4457 9905-9906 -COMMA- denotes ,
T4458 9907-9912 NN denotes ErbB4
T4459 9912-9913 -COMMA- denotes ,
T4460 9914-9919 NN denotes Ezrin
T4461 9919-9920 -COMMA- denotes ,
T4462 9921-9927 NN denotes SIMPLE
T4463 9927-9928 -COMMA- denotes ,
T4464 9929-9934 NN denotes c-Jun
T4465 9934-9935 -COMMA- denotes ,
T4466 9936-9941 NN denotes RUNX4
T4467 9941-9942 -COMMA- denotes ,
T4468 9943-9946 CC denotes and
T4469 9947-9951 JJ denotes many
T4470 9952-9958 NN denotes others
T4471 9959-9960 -LRB- denotes (
T4472 9960-9965 NNP denotes Chang
T4473 9966-9968 FW denotes et
T4474 9969-9972 FW denotes al.
T4475 9972-9973 -COMMA- denotes ,
T4476 9974-9978 CD denotes 2007
T4477 9978-9979 -COLON- denotes ;
T4478 9980-9985 NNP denotes Salah
T4479 9986-9988 FW denotes et
T4480 9989-9992 FW denotes al.
T4481 9992-9993 -COMMA- denotes ,
T4482 9994-9998 CD denotes 2012
T4483 9998-9999 -COLON- denotes ;
T4484 10000-10002 NNP denotes Su
T4485 10003-10005 FW denotes et
T4486 10006-10009 FW denotes al.
T4487 10009-10010 -COMMA- denotes ,
T4488 10011-10015 CD denotes 2012
T4489 10015-10016 -COLON- denotes ;
T4490 10017-10023 NN denotes Figure
T4491 10024-10025 CD denotes 1
T4492 10025-10026 -RRB- denotes )
T4493 10028-10039 RB denotes Transiently
T4494 10040-10053 VB denotes overexpressed
T4495 10054-10058 NN denotes WWOX
T4496 10059-10064 VB denotes binds
T4497 10065-10078 NN denotes transcription
T4498 10079-10086 NN denotes factors
T4499 10087-10091 NN denotes AP-2
T4500 10091-10092 -COMMA- denotes ,
T4501 10093-10096 NN denotes p73
T4502 10096-10097 -COMMA- denotes ,
T4503 10098-10101 CC denotes and
T4504 10102-10107 NN denotes c-Jun
T4505 10108-10111 CC denotes and
T4506 10112-10117 VB denotes block
T4507 10118-10123 PRP-DOLLAR- denotes their
T4508 10124-10131 JJ denotes nuclear
T4509 10132-10142 NN denotes relocation
T4510 10143-10145 FW denotes in
T4511 10146-10151 FW denotes vitro
T4512 10151-10152 -COMMA- denotes ,
T4513 10153-10158 WDT denotes which
T4514 10159-10169 VB denotes suppresses
T4515 10170-10176 NN denotes cancer
T4516 10177-10181 NN denotes cell
T4517 10182-10190 NN denotes survival
T4518 10191-10192 -LRB- denotes (
T4519 10192-10197 NNP denotes Salah
T4520 10198-10200 FW denotes et
T4521 10201-10204 FW denotes al.
T4522 10204-10205 -COMMA- denotes ,
T4523 10206-10210 CD denotes 2012
T4524 10210-10211 -RRB- denotes )
T4525 10213-10215 IN denotes In
T4526 10216-10221 JJ denotes stark
T4527 10222-10230 NN denotes contrast
T4528 10230-10231 -COMMA- denotes ,
T4529 10232-10236 NNP denotes Wwox
T4530 10237-10248 NN denotes co-migrates
T4531 10249-10253 IN denotes with
T4532 10254-10266 JJ denotes proapoptotic
T4533 10267-10270 CC denotes and
T4534 10271-10283 JJ denotes pro-survival
T4535 10284-10297 NN denotes transcription
T4536 10298-10305 NN denotes factors
T4537 10306-10308 TO denotes to
T4538 10309-10312 DT denotes the
T4539 10313-10319 NN denotes nuclei
T4540 10320-10322 IN denotes of
T4541 10323-10330 NN denotes neurons
T4542 10331-10335 IN denotes upon
T4543 10336-10343 JJ denotes sciatic
T4544 10344-10349 NN denotes nerve
T4545 10350-10357 NN denotes axotomy
T4546 10358-10360 IN denotes in
T4547 10361-10365 NN denotes rats
T4548 10366-10367 -LRB- denotes (
T4549 10367-10369 NNP denotes Li
T4550 10370-10372 FW denotes et
T4551 10373-10376 FW denotes al.
T4552 10376-10377 -COMMA- denotes ,
T4553 10378-10382 CD denotes 2009
T4554 10382-10383 -RRB- denotes )
T4555 10385-10387 DT denotes No
T4556 10388-10396 NN denotes blocking
T4557 10397-10399 IN denotes of
T4558 10400-10413 NN denotes translocation
T4559 10414-10416 IN denotes of
T4560 10417-10430 NN denotes transcription
T4561 10431-10438 NN denotes factors
T4562 10439-10441 TO denotes to
T4563 10442-10445 DT denotes the
T4564 10446-10452 NN denotes nuclei
T4565 10453-10455 IN denotes by
T4566 10456-10460 NN denotes Wwox
T4567 10461-10464 VB denotes was
T4568 10465-10473 VB denotes observed
T4569 10475-10480 IN denotes Under
T4570 10481-10487 NN denotes stress
T4571 10488-10498 NN denotes conditions
T4572 10498-10499 -COMMA- denotes ,
T4573 10500-10504 NN denotes WWOX
T4574 10505-10507 VB denotes is
T4575 10508-10517 VB denotes activated
T4576 10518-10521 IN denotes via
T4577 10522-10537 NN denotes phosphorylation
T4578 10538-10540 IN denotes at
T4579 10541-10546 NN denotes Tyr33
T4580 10546-10547 -COMMA- denotes ,
T4581 10548-10551 CC denotes and
T4582 10552-10557 VB denotes binds
T4583 10558-10566 NN denotes proteins
T4584 10567-10580 RB denotes independently
T4585 10581-10583 IN denotes of
T4586 10584-10587 DT denotes the
T4587 10588-10592 NN denotes PPxY
T4588 10593-10598 NN denotes motif
T4589 10599-10600 -LRB- denotes (
T4590 10600-10605 NNP denotes Chang
T4591 10606-10608 FW denotes et
T4592 10609-10612 FW denotes al.
T4593 10612-10613 -COMMA- denotes ,
T4594 10614-10618 CD denotes 2001
T4595 10618-10619 -COMMA- denotes ,
T4596 10620-10624 CD denotes 2003
T4597 10624-10625 -COMMA- denotes ,
T4598 10626-10631 NN denotes 2005a
T4599 10631-10632 -COMMA- denotes ,
T4600 10632-10633 NN denotes b
T4601 10633-10634 -COMMA- denotes ,
T4602 10635-10639 CD denotes 2007
T4603 10639-10640 -COMMA- denotes ,
T4604 10641-10645 CD denotes 2010
T4605 10645-10646 -RRB- denotes )
T4606 10648-10657 VB denotes Activated
T4607 10658-10662 NN denotes WWOX
T4608 10663-10673 RB denotes physically
T4609 10674-10683 VB denotes interacts
T4610 10684-10688 IN denotes with
T4611 10689-10695 NN denotes serine
T4612 10696-10713 JJ denotes 46-phosphorylated
T4613 10714-10717 NN denotes p53
T4614 10718-10719 -LRB- denotes (
T4615 10719-10725 NN denotes Figure
T4616 10726-10727 CD denotes 1
T4617 10727-10728 -RRB- denotes )
T4618 10728-10729 -COMMA- denotes ,
T4619 10730-10735 WDT denotes which
T4620 10736-10746 VB denotes stabilizes
T4621 10747-10750 NN denotes p53
T4622 10751-10754 CC denotes and
T4623 10755-10758 PRP-DOLLAR- denotes its
T4624 10759-10768 JJ denotes apoptotic
T4625 10769-10777 NN denotes function
T4626 10778-10779 -LRB- denotes (
T4627 10779-10784 NNP denotes Chang
T4628 10785-10787 FW denotes et
T4629 10788-10791 FW denotes al.
T4630 10791-10792 -COMMA- denotes ,
T4631 10793-10798 NN denotes 2005b
T4632 10798-10799 -RRB- denotes )
T4633 10801-10805 RB denotes Also
T4634 10805-10806 -COMMA- denotes ,
T4635 10807-10811 NN denotes WWOX
T4636 10812-10817 VB denotes binds
T4637 10818-10828 VB denotes Disheveled
T4638 10829-10837 NN denotes proteins
T4639 10838-10839 -LRB- denotes (
T4640 10839-10842 NN denotes Dvl
T4641 10842-10843 -RRB- denotes )
T4642 10843-10844 -COMMA- denotes ,
T4643 10845-10850 WDT denotes which
T4644 10851-10854 VB denotes are
T4645 10855-10858 JJ denotes key
T4646 10859-10869 NN denotes components
T4647 10870-10872 IN denotes in
T4648 10873-10886 NN denotes Wnt/β-catenin
T4649 10887-10896 NN denotes signaling
T4650 10897-10904 NN denotes pathway
T4651 10905-10906 -LRB- denotes (
T4652 10906-10912 NN denotes Figure
T4653 10913-10914 CD denotes 1
T4654 10914-10915 -RRB- denotes )
T4655 10917-10919 DT denotes No
T4656 10920-10924 NN denotes PPxY
T4657 10925-10930 NN denotes motif
T4658 10931-10933 VB denotes is
T4659 10934-10936 IN denotes in
T4660 10937-10941 NNP denotes Dvl.
T4661 10942-10953 NNP denotes Transiently
T4662 10954-10967 VB denotes overexpressed
T4663 10968-10972 NN denotes WWOX
T4664 10973-10983 NN denotes sequesters
T4665 10984-10989 NN denotes Dvl-2
T4666 10990-10992 IN denotes in
T4667 10993-10996 DT denotes the
T4668 10997-11006 NN denotes cytoplasm
T4669 11007-11010 CC denotes and
T4670 11011-11018 RB denotes thereby
T4671 11019-11025 VB denotes blocks
T4672 11026-11040 JJ denotes Dvl-2-mediated
T4673 11041-11044 NN denotes TCF
T4674 11045-11060 JJ denotes transcriptional
T4675 11061-11069 NN denotes activity
T4676 11070-11071 -LRB- denotes (
T4677 11071-11080 NNP denotes Bouteille
T4678 11081-11083 FW denotes et
T4679 11084-11087 FW denotes al.
T4680 11087-11088 -COMMA- denotes ,
T4681 11089-11093 CD denotes 2009
T4682 11093-11094 -RRB- denotes )
T4683 11096-11109 VB denotes Overexpressed
T4684 11110-11114 NN denotes WWOX
T4685 11115-11122 VB denotes induces
T4686 11123-11132 NN denotes apoptosis
T4687 11133-11136 CC denotes and
T4688 11137-11145 VB denotes inhibits
T4689 11146-11159 NN denotes proliferation
T4690 11160-11162 IN denotes of
T4691 11163-11168 JJ denotes human
T4692 11169-11176 JJ denotes hepatic
T4693 11177-11186 NN denotes carcinoma
T4694 11187-11192 NN denotes cells
T4695 11193-11194 -LRB- denotes (
T4696 11194-11196 NNP denotes Hu
T4697 11197-11199 FW denotes et
T4698 11200-11203 FW denotes al.
T4699 11203-11204 -COMMA- denotes ,
T4700 11205-11209 CD denotes 2012
T4701 11209-11210 -RRB- denotes )
T4702 11211-11214 CC denotes and
T4703 11215-11219 JJ denotes many
T4704 11220-11226 NN denotes cancer
T4705 11227-11231 NN denotes cell
T4706 11232-11237 NN denotes types
T4707 11238-11239 -LRB- denotes (
T4708 11239-11244 NNP denotes Chang
T4709 11245-11247 FW denotes et
T4710 11248-11251 FW denotes al.
T4711 11251-11252 -COMMA- denotes ,
T4712 11253-11257 CD denotes 2007
T4713 11257-11258 -COMMA- denotes ,
T4714 11259-11263 CD denotes 2010
T4715 11263-11264 -COLON- denotes ;
T4716 11265-11270 NNP denotes Salah
T4717 11271-11273 FW denotes et
T4718 11274-11277 FW denotes al.
T4719 11277-11278 -COMMA- denotes ,
T4720 11279-11283 CD denotes 2012
T4721 11283-11284 -COLON- denotes ;
T4722 11285-11287 NNP denotes Su
T4723 11288-11290 FW denotes et
T4724 11291-11294 FW denotes al.
T4725 11294-11295 -COMMA- denotes ,
T4726 11296-11300 CD denotes 2012
T4727 11300-11301 -RRB- denotes )
T4728 11303-11307 NN denotes WWOX
T4729 11308-11316 VB denotes enhances
T4730 11317-11320 DT denotes the
T4731 11321-11330 JJ denotes cytotoxic
T4732 11331-11339 NN denotes function
T4733 11340-11342 IN denotes of
T4734 11343-11348 NN denotes tumor
T4735 11349-11357 NN denotes necrosis
T4736 11358-11364 NN denotes factor
T4737 11365-11367 IN denotes by
T4738 11368-11383 VB denotes down-regulating
T4739 11384-11393 NN denotes apoptosis
T4740 11394-11403 NN denotes inhibitor
T4741 11404-11409 NN denotes Bcl-2
T4742 11410-11413 CC denotes and
T4743 11414-11420 NN denotes Bcl-xL
T4744 11421-11424 CC denotes and
T4745 11425-11438 VB denotes up-regulating
T4746 11439-11448 JJ denotes apoptotic
T4747 11449-11452 NN denotes p53
T4748 11453-11454 -LRB- denotes (
T4749 11454-11459 NNP denotes Chang
T4750 11460-11462 FW denotes et
T4751 11463-11466 FW denotes al.
T4752 11466-11467 -COMMA- denotes ,
T4753 11468-11472 CD denotes 2001
T4754 11472-11473 -RRB- denotes )
T4755 11475-11479 RB denotes Also
T4756 11479-11480 -COMMA- denotes ,
T4757 11481-11485 NN denotes WWOX
T4758 11486-11494 VB denotes mediates
T4759 11495-11499 NN denotes cell
T4760 11500-11505 NN denotes death
T4761 11506-11521 RB denotes synergistically
T4762 11522-11526 IN denotes with
T4763 11527-11530 NN denotes p53
T4764 11532-11536 IN denotes Upon
T4765 11537-11545 NN denotes exposure
T4766 11546-11548 TO denotes to
T4767 11549-11558 NN denotes chemicals
T4768 11559-11561 CC denotes or
T4769 11562-11575 JJ denotes environmental
T4770 11576-11582 NN denotes stress
T4771 11582-11583 -COMMA- denotes ,
T4772 11584-11588 JJ denotes such
T4773 11589-11591 IN denotes as
T4774 11592-11594 NN denotes UV
T4775 11595-11606 NN denotes irradiation
T4776 11607-11610 CC denotes and
T4777 11611-11627 JJ denotes chemotherapeutic
T4778 11628-11633 NN denotes drugs
T4779 11633-11634 -COMMA- denotes ,
T4780 11635-11639 NN denotes WWOX
T4781 11640-11649 VB denotes undergoes
T4782 11650-11665 NN denotes phosphorylation
T4783 11666-11668 IN denotes in
T4784 11669-11674 NN denotes Tyr33
T4785 11675-11678 CC denotes and
T4786 11679-11687 RB denotes probably
T4787 11688-11694 NN denotes others
T4788 11695-11700 NN denotes sites
T4789 11700-11701 -COMMA- denotes ,
T4790 11702-11710 VB denotes followed
T4791 11711-11713 IN denotes by
T4792 11714-11724 VB denotes relocating
T4793 11725-11727 TO denotes to
T4794 11728-11740 NN denotes mitochondria
T4795 11741-11743 CC denotes or
T4796 11744-11750 NN denotes nuclei
T4797 11751-11754 IN denotes for
T4798 11755-11763 VB denotes inducing
T4799 11764-11773 NN denotes apoptosis
T4800 11774-11775 -LRB- denotes (
T4801 11775-11780 NNP denotes Chang
T4802 11781-11783 FW denotes et
T4803 11784-11787 FW denotes al.
T4804 11787-11788 -COMMA- denotes ,
T4805 11789-11793 CD denotes 2007
T4806 11793-11794 -COMMA- denotes ,
T4807 11795-11799 CD denotes 2010
T4808 11799-11800 -RRB- denotes )
T4809 11802-11806 NN denotes WWOX
T4810 11807-11812 VB denotes binds
T4811 11813-11816 NN denotes MEK
T4812 11817-11819 IN denotes in
T4813 11820-11826 NN denotes Jurkat
T4814 11827-11828 NN denotes T
T4815 11829-11834 NN denotes cells
T4816 11835-11836 -LRB- denotes (
T4817 11836-11839 NNP denotes Lin
T4818 11840-11842 FW denotes et
T4819 11843-11846 FW denotes al.
T4820 11846-11847 -COMMA- denotes ,
T4821 11848-11852 CD denotes 2011
T4822 11852-11853 -RRB- denotes )
T4823 11855-11862 NN denotes Phorbol
T4824 11863-11872 NN denotes myristate
T4825 11873-11880 NN denotes acetate
T4826 11881-11882 -LRB- denotes (
T4827 11882-11885 NN denotes PMA
T4828 11885-11886 -RRB- denotes )
T4829 11887-11898 VB denotes dissociates
T4830 11899-11902 DT denotes the
T4831 11903-11911 NN denotes MEK/WWOX
T4832 11912-11919 NN denotes complex
T4833 11920-11923 CC denotes and
T4834 11924-11931 VB denotes induces
T4835 11932-11936 NN denotes WWOX
T4836 11937-11939 TO denotes to
T4837 11940-11951 VB denotes translocate
T4838 11952-11954 TO denotes to
T4839 11955-11958 DT denotes the
T4840 11959-11971 NN denotes mitochondria
T4841 11972-11974 TO denotes to
T4842 11975-11981 VB denotes induce
T4843 11982-11991 NN denotes apoptosis
T4844 11991-11992 -COMMA- denotes ,
T4845 11993-12000 IN denotes whereas
T4846 12001-12004 NN denotes MEK
T4847 12005-12014 VB denotes relocates
T4848 12015-12017 TO denotes to
T4849 12018-12021 DT denotes the
T4850 12022-12027 NN denotes lipid
T4851 12028-12032 NN denotes raft
T4852 12034-12044 NN denotes Inhibition
T4853 12045-12047 IN denotes of
T4854 12048-12051 NN denotes MEK
T4855 12052-12060 NN denotes activity
T4856 12061-12070 VB denotes increases
T4857 12071-12082 JJ denotes TMZ-induced
T4858 12083-12094 NN denotes suppression
T4859 12095-12097 IN denotes of
T4860 12098-12104 NN denotes cancer
T4861 12105-12109 NN denotes cell
T4862 12110-12116 NN denotes growth
T4863 12117-12118 -LRB- denotes (
T4864 12118-12122 NNP denotes Holt
T4865 12123-12125 FW denotes et
T4866 12126-12129 FW denotes al.
T4867 12129-12130 -COMMA- denotes ,
T4868 12131-12135 CD denotes 2012
T4869 12135-12136 -RRB- denotes )
T4870 12138-12145 JJ denotes Ectopic
T4871 12146-12156 NN denotes expression
T4872 12157-12159 IN denotes of
T4873 12160-12164 NN denotes WWOX
T4874 12165-12167 IN denotes in
T4875 12168-12172 NN denotes A549
T4876 12173-12178 NN denotes cells
T4877 12179-12186 VB denotes induces
T4878 12187-12199 NN denotes procaspase-3
T4879 12200-12203 CC denotes and
T4880 12204-12216 NN denotes procaspase-9
T4881 12217-12227 NN denotes activation
T4882 12228-12231 CC denotes and
T4883 12232-12239 VB denotes induces
T4884 12240-12250 NN denotes cytochrome
T4885 12251-12252 NN denotes C
T4886 12253-12262 VB denotes releasing
T4887 12263-12267 IN denotes from
T4888 12268-12271 DT denotes the
T4889 12272-12284 NN denotes mitochondria
T4890 12285-12286 -LRB- denotes (
T4891 12286-12291 NNP denotes Zhang
T4892 12292-12294 FW denotes et
T4893 12295-12298 FW denotes al.
T4894 12298-12299 -COMMA- denotes ,
T4895 12300-12305 NN denotes 2012a
T4896 12305-12306 -RRB- denotes )
T4897 12308-12318 NN denotes Complement
T4898 12319-12322 NN denotes C1q
T4899 12323-12330 VB denotes induces
T4900 12331-12338 JJ denotes ectopic
T4901 12339-12343 NN denotes WWOX
T4902 12344-12359 NN denotes phosphorylation
T4903 12360-12362 IN denotes in
T4904 12363-12368 NN denotes Try33
T4905 12369-12372 CC denotes and
T4906 12373-12378 VB denotes leads
T4907 12379-12381 TO denotes to
T4908 12382-12386 NN denotes cell
T4909 12387-12396 NN denotes apoptosis
T4910 12397-12410 RB denotes independently
T4911 12411-12413 IN denotes of
T4912 12414-12417 DT denotes the
T4913 12418-12427 JJ denotes classical
T4914 12428-12438 NN denotes complement
T4915 12439-12449 NN denotes activation
T4916 12450-12457 NN denotes pathway
T4917 12458-12459 -LRB- denotes (
T4918 12459-12463 NNP denotes Hong
T4919 12464-12466 FW denotes et
T4920 12467-12470 FW denotes al.
T4921 12470-12471 -COMMA- denotes ,
T4922 12472-12476 CD denotes 2009
T4923 12476-12477 -RRB- denotes )
T4924 12479-12480 DT denotes A
T4925 12481-12488 NN denotes portion
T4926 12489-12491 IN denotes of
T4927 12492-12496 NN denotes WWOX
T4928 12497-12499 VB denotes is
T4929 12500-12508 VB denotes anchored
T4930 12509-12511 IN denotes in
T4931 12512-12515 DT denotes the
T4932 12516-12537 NN denotes membrane/cytoskeleton
T4933 12538-12542 NN denotes area
T4934 12543-12546 IN denotes via
T4935 12547-12554 NN denotes binding
T4936 12555-12559 IN denotes with
T4937 12560-12573 NN denotes hyaluronidase
T4938 12574-12580 NN denotes Hyal-2
T4939 12581-12582 -LRB- denotes (
T4940 12582-12585 NNP denotes Hsu
T4941 12586-12588 FW denotes et
T4942 12589-12592 FW denotes al.
T4943 12592-12593 -COMMA- denotes ,
T4944 12594-12598 CD denotes 2009
T4945 12598-12599 -RRB- denotes )
T4946 12600-12603 CC denotes and
T4947 12604-12617 NN denotes Phospho-Ezrin
T4948 12618-12619 -LRB- denotes (
T4949 12619-12622 NNP denotes Jin
T4950 12623-12625 FW denotes et
T4951 12626-12629 FW denotes al.
T4952 12629-12630 -COMMA- denotes ,
T4953 12631-12635 CD denotes 2006
T4954 12635-12636 -RRB- denotes )
T4955 12638-12650 VB denotes Transforming
T4956 12651-12657 NN denotes growth
T4957 12658-12664 NN denotes factor
T4958 12665-12667 NN denotes β1
T4959 12668-12673 VB denotes binds
T4960 12674-12680 NN denotes Hyal-2
T4961 12681-12683 IN denotes as
T4962 12684-12685 DT denotes a
T4963 12686-12693 JJ denotes cognate
T4964 12694-12702 NN denotes receptor
T4965 12703-12705 TO denotes to
T4966 12706-12712 VB denotes signal
T4967 12713-12716 DT denotes the
T4968 12717-12726 NN denotes formation
T4969 12727-12729 IN denotes of
T4970 12730-12733 DT denotes the
T4971 12734-12751 JJ denotes WWOX/Hyal-2/Smad4
T4972 12752-12759 NN denotes complex
T4973 12760-12762 TO denotes to
T4974 12763-12771 VB denotes relocate
T4975 12772-12774 TO denotes to
T4976 12775-12778 DT denotes the
T4977 12779-12786 NN denotes nucleus
T4978 12787-12790 IN denotes for
T4979 12791-12800 VB denotes enhancing
T4980 12801-12804 DT denotes the
T4981 12805-12816 JJ denotes SMAD-driven
T4982 12817-12825 NN denotes promoter
T4983 12826-12834 NN denotes activity
T4984 12835-12836 -LRB- denotes (
T4985 12836-12839 NNP denotes Hsu
T4986 12840-12842 FW denotes et
T4987 12843-12846 FW denotes al.
T4988 12846-12847 -COMMA- denotes ,
T4989 12848-12852 CD denotes 2009
T4990 12852-12853 -RRB- denotes )
T6867 12874-12883 VB denotes Activated
T6868 12884-12887 NN denotes p53
T6869 12888-12896 VB denotes mediates
T6870 12897-12906 NN denotes apoptosis
T6871 12906-12907 -COMMA- denotes ,
T6872 12908-12912 NN denotes cell
T6873 12913-12918 NN denotes cycle
T6874 12919-12925 NN denotes arrest
T6875 12925-12926 -COMMA- denotes ,
T6876 12927-12937 NN denotes senescence
T6877 12937-12938 -COMMA- denotes ,
T6878 12939-12942 NN denotes DNA
T6879 12943-12949 NN denotes repair
T6880 12949-12950 -COMMA- denotes ,
T6881 12951-12953 CC denotes or
T6882 12954-12964 NN denotes metabolism
T6883 12965-12966 -LRB- denotes (
T6884 12966-12970 NN denotes Lane
T6885 12971-12974 CC denotes and
T6886 12975-12981 NNP denotes Levine
T6887 12981-12982 -COMMA- denotes ,
T6888 12983-12987 CD denotes 2010
T6889 12987-12988 -RRB- denotes )
T6890 12990-12993 DT denotes The
T6891 12994-13001 JJ denotes primary
T6892 13002-13012 NN denotes structures
T6893 13013-13015 IN denotes of
T6894 13016-13019 NN denotes p53
T6895 13020-13023 CC denotes and
T6896 13024-13027 PRP-DOLLAR- denotes its
T6897 13028-13036 NN denotes isoforms
T6898 13037-13040 VB denotes are
T6899 13041-13049 VB denotes depicted
T6900 13050-13051 -LRB- denotes (
T6901 13051-13057 NN denotes Figure
T6902 13058-13059 CD denotes 2
T6903 13059-13060 -RRB- denotes )
T6904 13060-13063 NN denotes . p
T6905 13063-13070 VB denotes 53 indu
T6906 13070-13074 NN denotes ces
T6907 13074-13079 NN denotes cell
T6908 13079-13085 NN denotes cycle
T6909 13085-13087 IN denotes ar
T6910 13087-13102 VB denotes rest by transac
T6911 13102-13107 NN denotes tivat
T6912 13107-13111 JJ denotes ing
T6913 13111-13113 IN denotes ge
T6914 13113-13129 JJ denotes nes such as cycl
T6915 13129-13135 NN denotes in-dep
T6916 13135-13144 NN denotes endent ki
T6917 13144-13147 NN denotes nas
T6918 13147-13148 -COMMA- denotes e
T6919 13149-13151 CC denotes in
T6920 13151-13159 NN denotes hibitor
T6921 13159-13165 NN denotes p21, o
T6922 13165-13168 NN denotes r m
T6923 13168-13175 VB denotes icroRNA
T6924 13176-13185 NN denotes miR34. p5
T6925 13185-13187 IN denotes 3
T6926 13187-13202 VB denotes induces apoptos
T6927 13202-13214 JJ denotes is by transa
T6928 13214-13219 NN denotes ctiva
T6929 13219-13223 JJ denotes ting
T6930 13224-13226 IN denotes pr
T6931 13226-13229 NN denotes oap
T6932 13229-13230 -COMMA- denotes o
T6933 13230-13234 NN denotes ptot
T6934 13234-13235 -COMMA- denotes i
T6935 13235-13241 NN denotes c gene
T6936 13241-13242 -COMMA- denotes s
T6937 13243-13246 CC denotes suc
T6938 13246-13249 NN denotes h a
T6939 13249-13250 -COMMA- denotes s
T6940 13251-13254 CC denotes BAX
T6941 13254-13264 VB denotes , PUMA, SC
T6942 13264-13267 DT denotes OTI
T6943 13267-13280 JJ denotes N, and FAS, a
T6944 13280-13284 NN denotes nd i
T6945 13284-13289 NN denotes nhibi
T6946 13289-13290 -LRB- denotes t
T6947 13290-13294 NNP denotes ing
T6948 13294-13297 CC denotes the
T6949 13298-13304 NNP denotes antiap
T6950 13304-13305 -COMMA- denotes o
T6951 13305-13309 CD denotes ptot
T6952 13309-13310 -RRB- denotes i
T6953 13310-13313 NN denotes c g
T6954 13313-13321 VB denotes ene BCL-
T6955 13321-13333 JJ denotes 2 (Lane and
T6956 13333-13335 CC denotes Le
T6957 13335-13339 NN denotes vine
T6958 13339-13344 NN denotes , 201
T6959 13344-13352 NN denotes 0). p53
T6960 13352-13353 -COMMA- denotes t
T6961 13353-13362 VB denotes riggers p
T6962 13362-13366 IN denotes ro-s
T6963 13366-13370 NN denotes urvi
T6964 13370-13375 NN denotes val o
T6965 13375-13376 -COMMA- denotes r
T6966 13377-13380 DT denotes cel
T6967 13380-13389 NN denotes l death r
T6968 13389-13391 IN denotes es
T6969 13391-13394 DT denotes pon
T6970 13394-13400 NN denotes se, de
T6971 13400-13406 NN denotes pendin
T6972 13406-13407 -COMMA- denotes g
T6973 13408-13411 CC denotes upo
T6974 13411-13414 DT denotes n c
T6975 13414-13420 NN denotes ell ty
T6976 13420-13422 IN denotes pe
T6977 13422-13430 JJ denotes s, the i
T6978 13430-13436 NN denotes ntensi
T6979 13436-13437 -LRB- denotes t
T6980 13437-13445 NNP denotes y of the
T6981 13446-13448 FW denotes st
T6982 13448-13451 FW denotes res
T6983 13451-13452 -COMMA- denotes s
T6984 13453-13457 CD denotes sign
T6985 13457-13458 -RRB- denotes a
T6986 13520-13524 RB denotes Also
T6987 13524-13525 -COMMA- denotes ,
T6988 13526-13529 NN denotes p53
T6989 13530-13535 VB denotes plays
T6990 13536-13537 DT denotes a
T6991 13538-13542 NN denotes role
T6992 13543-13545 IN denotes in
T6993 13546-13557 VB denotes controlling
T6994 13558-13562 NN denotes cell
T6995 13563-13571 NN denotes motility
T6996 13572-13575 IN denotes via
T6997 13576-13586 VB denotes regulating
T6998 13587-13590 DT denotes the
T6999 13591-13601 NN denotes expression
T7000 13602-13604 IN denotes of
T7001 13605-13611 JJ denotes smooth
T7002 13612-13618 NN denotes muscle
T7003 13619-13626 NN denotes α-actin
T7004 13627-13628 -LRB- denotes (
T7005 13628-13633 NNP denotes Comer
T7006 13634-13636 FW denotes et
T7007 13637-13640 FW denotes al.
T7008 13640-13641 -COMMA- denotes ,
T7009 13642-13646 CD denotes 1998
T7010 13646-13647 -RRB- denotes )
T7011 13647-13648 -COMMA- denotes ,
T7012 13649-13658 NN denotes collagens
T7013 13659-13663 NN denotes IIα1
T7014 13664-13667 CC denotes and
T7015 13668-13672 NN denotes VIα1
T7016 13673-13674 -LRB- denotes (
T7017 13674-13677 NNP denotes Sun
T7018 13678-13680 FW denotes et
T7019 13681-13684 FW denotes al.
T7020 13684-13685 -COMMA- denotes ,
T7021 13686-13690 CD denotes 1999
T7022 13690-13691 -RRB- denotes )
T7023 13691-13692 -COMMA- denotes ,
T7024 13693-13696 CC denotes and
T7025 13697-13701 JJ denotes many
T7026 13702-13708 NN denotes others
T14173 13720-13723 NN denotes p53
T14174 13724-13727 CC denotes and
T14175 13728-13732 NN denotes WWOX
T14176 13733-13735 IN denotes in
T14177 13736-13739 NN denotes GBM
T14178 13740-13744 NN denotes cell
T14179 13745-13755 NN denotes apoptosis.
T14180 13756-13757 -LRB- denotes (
T14181 13757-13758 NN denotes A
T14182 13758-13759 -RRB- denotes )
T14183 13760-13771 JJ denotes Full-length
T14184 13772-13775 NN denotes p53
T14185 13776-13785 VB denotes possesses
T14186 13786-13789 CD denotes two
T14187 13790-13800 JJ denotes N-terminal
T14188 13801-13816 NN denotes transactivation
T14189 13817-13823 JJ denotes acidic
T14190 13824-13831 NN denotes domains
T14191 13831-13832 -COMMA- denotes ,
T14192 13833-13834 DT denotes a
T14193 13835-13847 JJ denotes proline-rich
T14194 13848-13854 NN denotes domain
T14195 13854-13855 -COMMA- denotes ,
T14196 13856-13857 DT denotes a
T14197 13858-13865 JJ denotes central
T14198 13866-13877 JJ denotes DNA-binding
T14199 13878-13884 NN denotes region
T14200 13884-13885 -COMMA- denotes ,
T14201 13886-13889 CC denotes and
T14202 13890-13891 DT denotes a
T14203 13892-13902 JJ denotes C-terminal
T14204 13903-13909 NN denotes domain
T14205 13909-13910 -COMMA- denotes ,
T14206 13911-13921 VB denotes containing
T14207 13922-13923 DT denotes a
T14208 13924-13931 JJ denotes nuclear
T14209 13932-13944 NN denotes localization
T14210 13945-13951 NN denotes signal
T14211 13951-13952 -COMMA- denotes ,
T14212 13953-13955 DT denotes an
T14213 13956-13971 NN denotes oligomerization
T14214 13972-13978 NN denotes domain
T14215 13978-13979 -COMMA- denotes ,
T14216 13980-13983 CC denotes and
T14217 13984-13985 DT denotes a
T14218 13986-13991 JJ denotes basic
T14219 13992-13998 NN denotes region
T14220 14000-14010 JJ denotes N-terminal
T14221 14011-14019 NN denotes deletion
T14222 14020-14027 NN denotes mutants
T14223 14028-14030 IN denotes of
T14224 14031-14034 NN denotes p53
T14225 14035-14038 VB denotes are
T14226 14039-14043 RB denotes also
T14227 14044-14050 NN denotes shown.
T14228 14051-14052 -LRB- denotes (
T14229 14052-14053 NN denotes B
T14230 14053-14054 -RRB- denotes )
T14231 14055-14060 CD denotes Three
T14232 14061-14067 JJ denotes likely
T14233 14068-14077 NN denotes scenarios
T14234 14078-14081 VB denotes are
T14235 14082-14090 VB denotes proposed
T14236 14091-14094 IN denotes for
T14237 14095-14099 NN denotes WWOX
T14238 14100-14103 CC denotes and
T14239 14104-14107 NN denotes p53
T14240 14108-14110 TO denotes to
T14241 14111-14119 VB denotes regulate
T14242 14120-14123 NN denotes GBM
T14243 14124-14128 NN denotes cell
T14244 14129-14134 NN denotes death
T14245 14136-14141 RB denotes First
T14246 14141-14142 -COMMA- denotes ,
T14247 14143-14150 JJ denotes ectopic
T14248 14151-14155 NN denotes WWOX
T14249 14156-14161 VB denotes fails
T14250 14162-14164 TO denotes to
T14251 14165-14171 VB denotes induce
T14252 14172-14181 NN denotes apoptosis
T14253 14182-14184 IN denotes of
T14254 14185-14188 NN denotes GBM
T14255 14189-14194 NN denotes cells
T14256 14195-14205 VB denotes expressing
T14257 14206-14216 JJ denotes endogenous
T14258 14217-14221 JJ denotes wild
T14259 14222-14226 NN denotes type
T14260 14227-14230 NN denotes p53
T14261 14232-14234 PRP denotes It
T14262 14235-14242 VB denotes appears
T14263 14243-14247 IN denotes that
T14264 14248-14255 JJ denotes ectopic
T14265 14256-14260 NN denotes WWOX
T14266 14261-14266 VB denotes binds
T14267 14267-14270 CC denotes and
T14268 14271-14283 RB denotes functionally
T14269 14284-14295 VB denotes antagonizes
T14270 14296-14299 NN denotes p53
T14271 14299-14300 -COMMA- denotes ,
T14272 14301-14304 CC denotes and
T14273 14305-14309 DT denotes both
T14274 14310-14318 NN denotes proteins
T14275 14319-14326 VB denotes nullify
T14276 14327-14331 DT denotes each
T14277 14332-14339 NN denotes other’s
T14278 14340-14348 VB denotes function
T14279 14349-14351 IN denotes in
T14280 14352-14360 VB denotes inducing
T14281 14361-14370 NN denotes apoptosis
T14282 14372-14378 RB denotes Second
T14283 14378-14379 -COMMA- denotes ,
T14284 14380-14382 DT denotes no
T14285 14383-14391 JJ denotes physical
T14286 14392-14404 NN denotes interactions
T14287 14405-14412 IN denotes between
T14288 14413-14419 JJ denotes mutant
T14289 14420-14423 NN denotes p53
T14290 14424-14432 NN denotes proteins
T14291 14433-14436 CC denotes and
T14292 14437-14441 NN denotes WWOX
T14293 14442-14445 VB denotes are
T14294 14446-14454 VB denotes expected
T14295 14455-14457 IN denotes in
T14296 14458-14461 NN denotes GBM
T14297 14462-14467 NN denotes cells
T14298 14469-14473 RB denotes Thus
T14299 14473-14474 -COMMA- denotes ,
T14300 14475-14482 JJ denotes ectopic
T14301 14483-14487 NN denotes WWOX
T14302 14488-14494 VB denotes induce
T14303 14495-14504 NN denotes apoptosis
T14304 14505-14507 IN denotes in
T14305 14508-14514 JJ denotes mutant
T14306 14515-14529 JJ denotes p53-expressing
T14307 14530-14535 NN denotes cells
T14308 14537-14544 RB denotes Finally
T14309 14544-14545 -COMMA- denotes ,
T14310 14546-14553 IN denotes whether
T14311 14554-14558 NN denotes WWOX
T14312 14559-14564 VB denotes binds
T14313 14565-14568 NN denotes p53
T14314 14569-14577 NN denotes isoforms
T14315 14578-14580 VB denotes is
T14316 14581-14588 JJ denotes unknown
T14317 14590-14594 RB denotes Also
T14318 14594-14595 -COMMA- denotes ,
T14319 14596-14603 IN denotes whether
T14320 14604-14611 JJ denotes ectopic
T14321 14612-14616 NN denotes WWOX
T14322 14617-14626 NN denotes induction
T14323 14627-14629 IN denotes of
T14324 14630-14639 NN denotes apoptosis
T14325 14640-14642 IN denotes in
T14326 14643-14646 NN denotes GBM
T14327 14647-14652 NN denotes cells
T14328 14653-14663 VB denotes expressing
T14329 14664-14667 NN denotes p53
T14330 14668-14676 NN denotes isoforms
T14331 14677-14684 VB denotes remains
T14332 14685-14687 TO denotes to
T14333 14688-14690 VB denotes be
T14334 14691-14702 VB denotes established
T14335 14704-14707 NN denotes TAD
T14336 14707-14708 -COMMA- denotes ,
T14337 14709-14724 NN denotes transactivation
T14338 14725-14731 NN denotes domain
T14339 14731-14732 -COLON- denotes ;
T14340 14733-14736 NN denotes PrD
T14341 14736-14737 -COMMA- denotes ,
T14342 14738-14745 NN denotes proline
T14343 14746-14752 NN denotes domain
T14344 14752-14753 -COLON- denotes ;
T14345 14754-14757 NN denotes NLS
T14346 14757-14758 -COMMA- denotes ,
T14347 14759-14766 JJ denotes nuclear
T14348 14767-14779 NN denotes localization
T14349 14780-14786 NN denotes signal
T14350 14786-14787 -COLON- denotes ;
T14351 14788-14790 NN denotes OD
T14352 14790-14791 -COMMA- denotes ,
T14353 14792-14807 NN denotes oligomerization
T14354 14808-14814 NN denotes domain
T14355 14814-14815 -COLON- denotes ;
T14356 14816-14818 NN denotes BR
T14357 14818-14819 -COMMA- denotes ,
T14358 14820-14825 JJ denotes basic
T14359 14826-14832 NN denotes region
T7620 14848-14850 IN denotes At
T7621 14851-14856 JJ denotes least
T7622 14857-14861 CD denotes nine
T7623 14862-14870 NN denotes isoforms
T7624 14871-14873 IN denotes of
T7625 14874-14877 NN denotes p53
T7626 14878-14882 VB denotes have
T7627 14883-14887 VB denotes been
T7628 14888-14898 VB denotes identified
T7629 14899-14902 JJ denotes due
T7630 14903-14905 TO denotes to
T7631 14906-14917 JJ denotes alternative
T7632 14918-14922 NN denotes mRNA
T7633 14923-14931 NN denotes splicing
T7634 14931-14932 -COMMA- denotes ,
T7635 14933-14941 JJ denotes multiple
T7636 14942-14946 NN denotes gene
T7637 14947-14956 NN denotes promoters
T7638 14956-14957 -COMMA- denotes ,
T7639 14958-14961 CC denotes and
T7640 14962-14973 JJ denotes alternative
T7641 14974-14984 NN denotes initiation
T7642 14985-14990 NN denotes sites
T7643 14991-14993 IN denotes of
T7644 14994-15005 NN denotes translation
T7645 15006-15007 -LRB- denotes (
T7646 15007-15012 NNP denotes Ghosh
T7647 15013-15015 FW denotes et
T7648 15016-15019 FW denotes al.
T7649 15019-15020 -COMMA- denotes ,
T7650 15021-15025 CD denotes 2004
T7651 15025-15026 -COLON- denotes ;
T7652 15027-15030 NNP denotes Ray
T7653 15031-15033 FW denotes et
T7654 15034-15037 FW denotes al.
T7655 15037-15038 -COMMA- denotes ,
T7656 15039-15043 CD denotes 2006
T7657 15043-15044 -COLON- denotes ;
T7658 15045-15051 NN denotes Figure
T7659 15052-15053 CD denotes 2
T7660 15053-15054 -RRB- denotes )
T7661 15056-15058 IN denotes In
T7662 15059-15066 NN denotes cancers
T7663 15066-15067 -COMMA- denotes ,
T7664 15068-15076 JJ denotes aberrant
T7665 15077-15087 NN denotes expression
T7666 15088-15090 IN denotes of
T7667 15091-15094 NN denotes p53
T7668 15095-15103 NN denotes isoforms
T7669 15104-15110 VB denotes occurs
T7670 15111-15121 RB denotes frequently
T7671 15122-15123 -LRB- denotes (
T7672 15123-15130 NNP denotes Bourdon
T7673 15131-15133 FW denotes et
T7674 15134-15137 FW denotes al.
T7675 15137-15138 -COMMA- denotes ,
T7676 15139-15143 CD denotes 2005
T7677 15143-15144 -COLON- denotes ;
T7678 15145-15152 NNP denotes Bourdon
T7679 15152-15153 -COMMA- denotes ,
T7680 15154-15158 CD denotes 2007
T7681 15158-15159 -RRB- denotes )
T7682 15161-15172 JJ denotes Full-length
T7683 15173-15176 NN denotes p53
T7684 15176-15177 -COMMA- denotes ,
T7685 15178-15185 NN denotes Δ133p53
T7686 15185-15186 -COMMA- denotes ,
T7687 15187-15190 CC denotes and
T7688 15191-15195 NN denotes p53β
T7689 15196-15199 VB denotes are
T7690 15200-15209 VB denotes localized
T7691 15210-15216 RB denotes mainly
T7692 15217-15219 IN denotes in
T7693 15220-15223 DT denotes the
T7694 15224-15231 NN denotes nucleus
T7695 15231-15232 -COMMA- denotes ,
T7696 15233-15236 CC denotes and
T7697 15237-15241 RB denotes only
T7698 15242-15245 JJ denotes few
T7699 15246-15248 IN denotes of
T7700 15249-15253 PRP denotes them
T7701 15254-15257 VB denotes are
T7702 15258-15260 IN denotes in
T7703 15261-15271 NN denotes cytoplasm.
T7704 15272-15276 NN denotes p53γ
T7705 15277-15280 CC denotes and
T7706 15281-15289 NN denotes Δ133p53β
T7707 15290-15293 VB denotes are
T7708 15294-15303 VB denotes localized
T7709 15304-15306 IN denotes in
T7710 15307-15310 DT denotes the
T7711 15311-15318 NN denotes nucleus
T7712 15319-15322 CC denotes and
T7713 15323-15333 NN denotes cytoplasm.
T7714 15334-15342 NN denotes Δ133p53γ
T7715 15343-15345 VB denotes is
T7716 15346-15355 JJ denotes localized
T7717 15356-15358 IN denotes in
T7718 15359-15362 DT denotes the
T7719 15363-15372 NN denotes cytoplasm
T7720 15373-15374 -LRB- denotes (
T7721 15374-15381 NNP denotes Bourdon
T7722 15382-15384 FW denotes et
T7723 15385-15388 FW denotes al.
T7724 15388-15389 -COMMA- denotes ,
T7725 15390-15394 CD denotes 2005
T7726 15394-15395 -RRB- denotes )
T7727 15397-15412 NN denotes Co-transfection
T7728 15413-15415 IN denotes of
T7729 15416-15419 NN denotes p53
T7730 15420-15423 CC denotes and
T7731 15424-15428 NN denotes p53β
T7732 15429-15438 VB denotes increases
T7733 15439-15451 JJ denotes p53-mediated
T7734 15452-15461 NN denotes apoptosis
T7735 15461-15462 -COMMA- denotes ,
T7736 15463-15470 IN denotes whereas
T7737 15471-15484 NN denotes co-expression
T7738 15485-15487 IN denotes of
T7739 15488-15491 NN denotes p53
T7740 15492-15496 IN denotes with
T7741 15497-15504 NN denotes Δ133p53
T7742 15505-15515 VB denotes suppresses
T7743 15516-15528 JJ denotes p53-mediated
T7744 15529-15538 NN denotes apoptosis
T7745 15539-15540 -LRB- denotes (
T7746 15540-15547 NNP denotes Bourdon
T7747 15548-15550 FW denotes et
T7748 15551-15554 FW denotes al.
T7749 15554-15555 -COMMA- denotes ,
T7750 15556-15560 CD denotes 2005
T7751 15560-15561 -RRB- denotes )
T7752 15561-15568 -DQE- denotes . Δ133p
T7753 15568-15582 RB denotes 53 differentia
T7754 15582-15591 VB denotes lly regul
T7755 15591-15595 NN denotes ates
T7756 15596-15606 NN denotes gene expre
T7757 15606-15608 IN denotes ss
T7758 15608-15621 JJ denotes ion in p53-de
T7759 15621-15624 CC denotes pen
T7760 15624-15636 JJ denotes dent and -in
T7761 15636-15643 NN denotes depende
T7762 15643-15644 -LRB- denotes n
T7763 15644-15651 NNP denotes t manne
T7764 15651-15653 FW denotes rs
T7765 15654-15657 FW denotes (Ao
T7766 15657-15658 -COMMA- denotes u
T7767 15658-15662 CD denotes bala
T7768 15663-15664 -RRB- denotes e
T7769 15678-15691 NN denotes Co-expression
T7770 15692-15694 IN denotes of
T7771 15695-15703 NN denotes Δ133p53β
T7772 15704-15706 CC denotes or
T7773 15707-15715 NN denotes Δ133p53γ
T7774 15716-15720 IN denotes with
T7775 15721-15724 NN denotes p53
T7776 15725-15729 VB denotes does
T7777 15730-15733 RB denotes not
T7778 15734-15740 VB denotes affect
T7779 15741-15744 NN denotes p53
T7780 15745-15760 JJ denotes transcriptional
T7781 15761-15769 NN denotes activity
T7782 15770-15772 IN denotes on
T7783 15773-15776 NN denotes p21
T7784 15777-15780 CC denotes and
T7785 15781-15784 NN denotes Bax
T7786 15785-15794 NN denotes promoters
T7787 15794-15795 -COMMA- denotes ,
T7788 15796-15798 RB denotes as
T7789 15799-15803 RB denotes well
T7790 15804-15806 IN denotes as
T7791 15807-15816 NN denotes apoptosis
T8540 15852-15855 NN denotes p53
T8541 15856-15863 NN denotes mutants
T8542 15864-15867 VB denotes are
T8543 15868-15878 VB denotes considered
T8544 15879-15881 IN denotes as
T8545 15882-15893 JJ denotes unfavorable
T8546 15894-15901 NN denotes factors
T8547 15902-15905 IN denotes for
T8548 15906-15909 DT denotes the
T8549 15910-15923 NN denotes effectiveness
T8550 15924-15926 IN denotes in
T8551 15927-15939 NN denotes radiotherapy
T8552 15940-15943 CC denotes and
T8553 15944-15947 NN denotes TMZ
T8554 15948-15957 NN denotes treatment
T8555 15958-15960 IN denotes in
T8556 15961-15967 NN denotes glioma
T8557 15968-15973 NN denotes cells
T8558 15974-15975 -LRB- denotes (
T8559 15975-15982 NN denotes Gjerset
T8560 15983-15985 FW denotes et
T8561 15986-15989 FW denotes al.
T8562 15989-15990 -COMMA- denotes ,
T8563 15991-15995 CD denotes 1995
T8564 15995-15996 -COLON- denotes ;
T8565 15997-16003 NNP denotes Hirose
T8566 16004-16006 FW denotes et
T8567 16007-16010 FW denotes al.
T8568 16010-16011 -COMMA- denotes ,
T8569 16012-16016 CD denotes 2001
T8570 16016-16017 -COLON- denotes ;
T8571 16018-16027 NNP denotes Squatrito
T8572 16028-16030 FW denotes et
T8573 16031-16034 FW denotes al.
T8574 16034-16035 -COMMA- denotes ,
T8575 16036-16040 CD denotes 2010
T8576 16040-16041 -COLON- denotes ;
T8577 16042-16048 NNP denotes Blough
T8578 16049-16051 FW denotes et
T8579 16052-16055 FW denotes al.
T8580 16055-16056 -COMMA- denotes ,
T8581 16057-16061 CD denotes 2011
T8582 16061-16062 -RRB- denotes )
T8583 16064-16068 NN denotes Loss
T8584 16069-16071 IN denotes of
T8585 16072-16082 JJ denotes functional
T8586 16083-16086 NN denotes p53
T8587 16087-16094 VB denotes confers
T8588 16095-16106 NN denotes sensitivity
T8589 16107-16109 TO denotes to
T8590 16110-16113 NN denotes TMZ
T8591 16114-16116 IN denotes in
T8592 16117-16123 NN denotes glioma
T8593 16124-16129 NN denotes cells
T8594 16129-16130 -COMMA- denotes ,
T8595 16131-16138 IN denotes whereas
T8596 16139-16143 JJ denotes wild
T8597 16144-16148 NN denotes type
T8598 16149-16152 NN denotes p53
T8599 16153-16162 VB denotes increases
T8600 16163-16166 DT denotes the
T8601 16167-16170 NN denotes TMZ
T8602 16171-16181 NN denotes resistance
T8603 16182-16183 -LRB- denotes (
T8604 16183-16189 NNP denotes Blough
T8605 16190-16192 FW denotes et
T8606 16193-16196 FW denotes al.
T8607 16196-16197 -COMMA- denotes ,
T8608 16198-16202 CD denotes 2011
T8609 16202-16203 -RRB- denotes )
T8610 16203-16206 NN denotes . p
T8611 16206-16213 NN denotes 53 muta
T8612 16213-16219 VB denotes nts re
T8613 16219-16222 NN denotes duc
T8614 16222-16233 NN denotes e TMZ sensi
T8615 16233-16235 IN denotes ti
T8616 16235-16242 NN denotes vity in
T8617 16243-16244 -LRB- denotes g
T8618 16244-16250 NNP denotes liomas
T8619 16251-16253 FW denotes (B
T8620 16253-16256 FW denotes lou
T8621 16256-16257 -COMMA- denotes g
T8622 16257-16261 CD denotes h et
T8623 16262-16263 -RRB- denotes a
T8624 16274-16281 VB denotes Altered
T8625 16282-16286 NN denotes WWOX
T8626 16287-16297 NN denotes expression
T8627 16298-16300 VB denotes is
T8628 16301-16306 VB denotes shown
T8629 16307-16309 IN denotes in
T8630 16310-16314 NN denotes GBMs
T8631 16314-16315 -COMMA- denotes ,
T8632 16316-16318 IN denotes in
T8633 16319-16324 WDT denotes which
T8634 16325-16339 NN denotes downregulation
T8635 16340-16342 IN denotes of
T8636 16343-16347 NN denotes WWOX
T8637 16348-16350 VB denotes is
T8638 16351-16361 VB denotes associated
T8639 16362-16366 IN denotes with
T8640 16367-16371 NN denotes loss
T8641 16372-16374 IN denotes of
T8642 16375-16389 NN denotes heterozygosity
T8643 16390-16393 CC denotes and
T8644 16394-16402 NN denotes promoter
T8645 16403-16414 NN denotes methylation
T8646 16415-16416 -LRB- denotes (
T8647 16416-16421 NNP denotes Kosla
T8648 16422-16424 FW denotes et
T8649 16425-16428 FW denotes al.
T8650 16428-16429 -COMMA- denotes ,
T8651 16430-16434 CD denotes 2011
T8652 16434-16435 -RRB- denotes )
T8653 16437-16445 RB denotes Recently
T8654 16445-16446 -COMMA- denotes ,
T8655 16447-16449 PRP denotes we
T8656 16450-16462 VB denotes demonstrated
T8657 16463-16467 IN denotes that
T8658 16468-16481 VB denotes overexpressed
T8659 16482-16486 NN denotes WWOX
T8660 16487-16494 VB denotes induces
T8661 16495-16504 NN denotes apoptosis
T8662 16505-16507 IN denotes of
T8663 16508-16520 NN denotes glioblastoma
T8664 16521-16528 NN denotes U373-MG
T8665 16529-16534 NN denotes cells
T8666 16535-16544 VB denotes harboring
T8667 16545-16551 JJ denotes mutant
T8668 16552-16555 NN denotes p53
T8669 16556-16558 IN denotes by
T8670 16559-16566 VB denotes causing
T8671 16567-16577 NN denotes hypoploidy
T8672 16578-16581 CC denotes and
T8673 16582-16585 NN denotes DNA
T8674 16586-16599 NN denotes fragmentation
T8675 16600-16601 -LRB- denotes (
T8676 16601-16607 NNP denotes Chiang
T8677 16608-16610 FW denotes et
T8678 16611-16614 FW denotes al.
T8679 16614-16615 -COMMA- denotes ,
T8680 16616-16620 CD denotes 2012
T8681 16620-16621 -RRB- denotes )
T8682 16623-16630 RB denotes However
T8683 16630-16631 -COMMA- denotes ,
T8684 16632-16639 JJ denotes ectopic
T8685 16640-16644 NN denotes WWOX
T8686 16645-16648 VB denotes has
T8687 16649-16651 DT denotes no
T8688 16652-16658 NN denotes effect
T8689 16659-16663 IN denotes with
T8690 16664-16670 NN denotes U87-MG
T8691 16671-16681 VB denotes expressing
T8692 16682-16686 JJ denotes wild
T8693 16687-16691 NN denotes type
T8694 16692-16695 NN denotes p53
T8695 16697-16703 IN denotes Unlike
T8696 16704-16707 NN denotes TMZ
T8697 16707-16708 -COMMA- denotes ,
T8698 16709-16713 NN denotes WWOX
T8699 16714-16721 VB denotes induces
T8700 16722-16731 NN denotes apoptosis
T8701 16732-16734 IN denotes of
T8702 16735-16742 NN denotes U373-MG
T8703 16743-16748 NN denotes cells
T8704 16749-16752 IN denotes via
T8705 16753-16754 DT denotes a
T8706 16755-16779 JJ denotes mitochondria-independent
T8707 16780-16783 CC denotes and
T8708 16784-16805 JJ denotes caspase-3-independent
T8709 16806-16813 NN denotes pathway
T8710 16814-16815 -LRB- denotes (
T8711 16815-16821 NNP denotes Chiang
T8712 16822-16824 FW denotes et
T8713 16825-16828 FW denotes al.
T8714 16828-16829 -COMMA- denotes ,
T8715 16830-16834 CD denotes 2012
T8716 16834-16835 -RRB- denotes )
T8717 16837-16842 IN denotes While
T8718 16843-16846 DT denotes the
T8719 16847-16857 VB denotes underlying
T8720 16858-16868 NN denotes mechanisms
T8721 16869-16872 VB denotes are
T8722 16873-16880 JJ denotes unknown
T8723 16880-16881 -COMMA- denotes ,
T8724 16882-16884 PRP denotes it
T8725 16885-16887 VB denotes is
T8726 16888-16898 JJ denotes reasonable
T8727 16899-16901 TO denotes to
T8728 16902-16908 VB denotes assume
T8729 16909-16913 IN denotes that
T8730 16914-16917 DT denotes the
T8731 16918-16926 NN denotes survival
T8732 16927-16929 IN denotes of
T8733 16930-16935 JJ denotes human
T8734 16936-16948 NN denotes glioblastoma
T8735 16949-16954 NN denotes cells
T8736 16955-16962 VB denotes depends
T8737 16963-16967 IN denotes upon
T8738 16968-16980 NN denotes interactions
T8739 16981-16988 IN denotes between
T8740 16989-16992 DT denotes the
T8741 16993-17009 NN denotes gain-of-function
T8742 17010-17012 IN denotes of
T8743 17013-17016 NN denotes p53
T8744 17017-17024 NN denotes mutants
T8745 17025-17028 CC denotes and
T8746 17029-17033 NN denotes WWOX
T8747 17035-17044 VB denotes Activated
T8748 17045-17049 NN denotes WWOX
T8749 17050-17055 VB denotes binds
T8750 17056-17060 JJ denotes wild
T8751 17061-17065 NN denotes type
T8752 17066-17069 NN denotes p53
T8753 17070-17074 IN denotes with
T8754 17075-17080 NN denotes Ser46
T8755 17081-17096 NN denotes phosphorylation
T8756 17097-17098 -LRB- denotes (
T8757 17098-17103 NNP denotes Chang
T8758 17104-17106 FW denotes et
T8759 17107-17110 FW denotes al.
T8760 17110-17111 -COMMA- denotes ,
T8761 17112-17117 NN denotes 2005b
T8762 17117-17118 -RRB- denotes )
T8763 17120-17122 NN denotes UV
T8764 17123-17134 NN denotes irradiation
T8765 17135-17143 VB denotes enhances
T8766 17144-17147 DT denotes the
T8767 17148-17155 NN denotes binding
T8768 17156-17168 NN denotes interactions
T8769 17170-17177 IN denotes Despite
T8770 17178-17181 DT denotes the
T8771 17182-17190 NN denotes presence
T8772 17191-17193 IN denotes of
T8773 17194-17199 NN denotes Ser46
T8774 17200-17202 IN denotes in
T8775 17203-17209 NN denotes Δ40p53
T8776 17209-17210 -COMMA- denotes ,
T8777 17211-17218 NN denotes binding
T8778 17219-17221 IN denotes of
T8779 17222-17226 DT denotes this
T8780 17227-17234 NN denotes protein
T8781 17235-17239 IN denotes with
T8782 17240-17244 NN denotes WWOX
T8783 17245-17252 VB denotes remains
T8784 17253-17255 TO denotes to
T8785 17256-17258 VB denotes be
T8786 17259-17269 VB denotes determined
T8787 17271-17273 PRP denotes We
T8788 17274-17283 VB denotes postulate
T8789 17284-17288 IN denotes that
T8790 17289-17291 IN denotes in
T8791 17292-17295 NN denotes GBM
T8792 17296-17301 NN denotes cells
T8793 17301-17302 -COMMA- denotes ,
T8794 17303-17307 DT denotes both
T8795 17308-17312 JJ denotes wild
T8796 17313-17317 NN denotes type
T8797 17318-17321 NN denotes p53
T8798 17322-17325 CC denotes and
T8799 17326-17333 JJ denotes ectopic
T8800 17334-17338 NN denotes WWOX
T8801 17339-17347 NN denotes proteins
T8802 17348-17354 VB denotes appear
T8803 17355-17357 TO denotes to
T8804 17358-17362 VB denotes have
T8805 17363-17364 DT denotes a
T8806 17365-17375 JJ denotes functional
T8807 17376-17386 NN denotes antagonism
T8808 17386-17387 -COMMA- denotes ,
T8809 17388-17395 RB denotes thereby
T8810 17396-17406 VB denotes nullifying
T8811 17407-17411 DT denotes each
T8812 17412-17419 NN denotes other’s
T8813 17420-17428 VB denotes function
T8814 17429-17431 IN denotes in
T8815 17432-17440 VB denotes inducing
T8816 17441-17450 NN denotes apoptosis
T8817 17451-17452 -LRB- denotes (
T8818 17452-17458 NN denotes Figure
T8819 17459-17460 CD denotes 2
T8820 17460-17461 -RRB- denotes )
T8821 17463-17469 JJ denotes Mutant
T8822 17470-17473 NN denotes p53
T8823 17474-17482 NN denotes proteins
T8824 17483-17486 MD denotes can
T8825 17486-17489 RB denotes not
T8826 17490-17494 VB denotes bind
T8827 17495-17502 JJ denotes ectopic
T8828 17503-17507 NN denotes WWOX
T8829 17508-17510 IN denotes in
T8830 17511-17514 NN denotes GBM
T8831 17515-17520 NN denotes cells
T8832 17520-17521 -COMMA- denotes ,
T8833 17522-17525 CC denotes and
T8834 17526-17530 NN denotes WWOX
T8835 17531-17533 VB denotes is
T8836 17534-17538 JJ denotes able
T8837 17539-17541 TO denotes to
T8838 17542-17548 VB denotes induce
T8839 17549-17558 NN denotes apoptosis
T8840 17560-17567 IN denotes Whether
T8841 17568-17572 NN denotes WWOX
T8842 17573-17579 VB denotes causes
T8843 17580-17589 NN denotes apoptosis
T8844 17590-17592 IN denotes in
T8845 17593-17596 NN denotes GBM
T8846 17597-17607 VB denotes expressing
T8847 17608-17611 NN denotes p53
T8848 17612-17620 NN denotes isoforms
T8849 17621-17623 VB denotes is
T8850 17624-17631 JJ denotes unknown
T8851 17632-17635 CC denotes and
T8852 17636-17643 VB denotes remains
T8853 17644-17646 TO denotes to
T8854 17647-17649 VB denotes be
T8855 17650-17661 VB denotes established
T10069 17677-17684 IN denotes Whether
T10070 17685-17689 NN denotes WWOX
T10071 17690-17697 VB denotes affects
T10072 17698-17701 NN denotes TMZ
T10073 17702-17713 NN denotes sensitivity
T10074 17714-17717 VB denotes has
T10075 17718-17723 RB denotes never
T10076 17724-17728 VB denotes been
T10077 17729-17739 VB denotes determined
T10078 17741-17748 NN denotes Binding
T10079 17749-17757 NN denotes proteins
T10080 17758-17761 IN denotes for
T10081 17762-17766 NN denotes WWOX
T10082 17767-17773 CC denotes and/or
T10083 17774-17777 NN denotes p53
T10084 17778-17781 VB denotes are
T10085 17782-17788 JJ denotes likely
T10086 17789-17791 TO denotes to
T10087 17792-17798 VB denotes affect
T10088 17799-17808 NN denotes apoptosis
T10089 17809-17812 CC denotes and
T10090 17813-17816 NN denotes TMZ
T10091 17817-17828 NN denotes sensitivity
T10092 17829-17831 IN denotes in
T10093 17832-17835 NN denotes GBM
T10094 17836-17841 NN denotes cells
T10095 17843-17847 NN denotes WWOX
T10096 17848-17853 VB denotes binds
T10097 17854-17857 NN denotes MEK
T10098 17857-17858 -COMMA- denotes ,
T10099 17859-17862 CC denotes and
T10100 17863-17867 IN denotes that
T10101 17868-17871 NN denotes PMA
T10102 17872-17883 VB denotes dissociates
T10103 17884-17888 DT denotes this
T10104 17889-17896 NN denotes complex
T10105 17897-17900 IN denotes for
T10106 17901-17908 VB denotes causing
T10107 17909-17918 NN denotes apoptosis
T10108 17919-17921 IN denotes of
T10109 17922-17923 NN denotes T
T10110 17924-17932 NN denotes leukemia
T10111 17933-17938 NN denotes cells
T10112 17939-17940 -LRB- denotes (
T10113 17940-17943 NNP denotes Lin
T10114 17944-17946 FW denotes et
T10115 17947-17950 FW denotes al.
T10116 17950-17951 -COMMA- denotes ,
T10117 17952-17956 CD denotes 2011
T10118 17956-17957 -RRB- denotes )
T10119 17959-17963 RB denotes Thus
T10120 17963-17964 -COMMA- denotes ,
T10121 17965-17976 JJ denotes appropriate
T10122 17977-17986 NN denotes chemicals
T10123 17986-17987 -COMMA- denotes ,
T10124 17988-17993 WDT denotes which
T10125 17994-17999 VB denotes break
T10126 18000-18005 RP denotes apart
T10127 18006-18009 DT denotes the
T10128 18010-18018 NN denotes WWOX/MEK
T10129 18019-18026 NN denotes complex
T10130 18026-18027 -COMMA- denotes ,
T10131 18028-18031 VB denotes are
T10132 18032-18040 VB denotes expected
T10133 18041-18043 TO denotes to
T10134 18044-18049 VB denotes cause
T10135 18050-18053 NN denotes GBM
T10136 18054-18058 NN denotes cell
T10137 18059-18064 NN denotes death
T10138 18066-18077 JJ denotes Preliminary
T10139 18078-18085 NN denotes studies
T10140 18086-18090 IN denotes from
T10141 18091-18094 PRP-DOLLAR- denotes our
T10142 18095-18104 NN denotes screening
T10143 18105-18107 IN denotes of
T10144 18108-18117 NN denotes chemicals
T10145 18118-18122 VB denotes have
T10146 18123-18131 VB denotes selected
T10147 18132-18139 JJ denotes certain
T10148 18140-18145 JJ denotes small
T10149 18146-18155 NN denotes molecules
T10150 18156-18160 WDT denotes that
T10151 18161-18167 VB denotes induce
T10152 18168-18177 NN denotes apoptosis
T10153 18178-18180 IN denotes of
T10154 18181-18185 JJ denotes many
T10155 18186-18191 NN denotes types
T10156 18192-18194 IN denotes of
T10157 18195-18201 NN denotes cancer
T10158 18202-18207 NN denotes cells
T10159 18208-18209 -LRB- denotes (
T10160 18209-18211 FW denotes Lu
T10161 18212-18214 FW denotes et
T10162 18215-18218 FW denotes al.
T10163 18218-18219 -COMMA- denotes ,
T10164 18220-18231 JJ denotes unpublished
T10165 18231-18232 -RRB- denotes )
T10166 18234-18240 RB denotes Indeed
T10167 18240-18241 -COMMA- denotes ,
T10168 18242-18250 JJ denotes specific
T10169 18251-18261 NN denotes inhibition
T10170 18262-18264 IN denotes of
T10171 18265-18268 NN denotes MEK
T10172 18269-18271 IN denotes by
T10173 18272-18283 NN denotes selumetinib
T10174 18284-18292 VB denotes enhances
T10175 18293-18304 JJ denotes TMZ-induced
T10176 18305-18311 NN denotes cancer
T10177 18312-18316 NN denotes cell
T10178 18317-18322 NN denotes death
T10179 18323-18325 FW denotes in
T10180 18326-18330 FW denotes vivo
T10181 18331-18332 -LRB- denotes (
T10182 18332-18336 NNP denotes Holt
T10183 18337-18339 FW denotes et
T10184 18340-18343 FW denotes al.
T10185 18343-18344 -COMMA- denotes ,
T10186 18345-18349 CD denotes 2012
T10187 18349-18350 -RRB- denotes )
T10188 18352-18357 NN denotes Serum
T10189 18358-18365 NN denotes factors
T10190 18366-18369 MD denotes can
T10191 18370-18372 VB denotes be
T10192 18373-18381 VB denotes utilized
T10193 18382-18385 IN denotes for
T10194 18386-18394 VB denotes blocking
T10195 18395-18401 NN denotes cancer
T10196 18402-18408 NN denotes growth
T10197 18410-18413 IN denotes For
T10198 18414-18421 NN denotes example
T10199 18421-18422 -COMMA- denotes ,
T10200 18423-18428 NN denotes serum
T10201 18429-18439 NN denotes complement
T10202 18440-18443 NN denotes C1q
T10203 18444-18451 VB denotes induces
T10204 18452-18461 NN denotes apoptosis
T10205 18462-18464 IN denotes of
T10206 18465-18473 NN denotes prostate
T10207 18474-18480 NN denotes cancer
T10208 18481-18484 CC denotes and
T10209 18485-18499 NN denotes neuroblastomas
T10210 18500-18505 NN denotes cells
T10211 18506-18513 IN denotes without
T10212 18514-18527 NN denotes participation
T10213 18528-18530 IN denotes of
T10214 18531-18541 JJ denotes downstream
T10215 18542-18550 NN denotes proteins
T10216 18551-18553 IN denotes in
T10217 18554-18557 DT denotes the
T10218 18558-18567 JJ denotes classical
T10219 18568-18578 NN denotes activation
T10220 18579-18586 NN denotes pathway
T10221 18587-18588 -LRB- denotes (
T10222 18588-18592 NNP denotes Hong
T10223 18593-18595 FW denotes et
T10224 18596-18599 FW denotes al.
T10225 18599-18600 -COMMA- denotes ,
T10226 18601-18605 CD denotes 2009
T10227 18605-18606 -RRB- denotes )
T10228 18608-18610 IN denotes In
T10229 18611-18615 DT denotes this
T10230 18616-18621 NN denotes event
T10231 18621-18622 -COMMA- denotes ,
T10232 18623-18630 JJ denotes ectopic
T10233 18631-18635 NN denotes WWOX
T10234 18636-18638 VB denotes is
T10235 18639-18648 VB denotes activated
T10236 18649-18652 IN denotes for
T10237 18653-18661 VB denotes inducing
T10238 18662-18671 NN denotes apoptosis
T10239 18673-18680 NN denotes Failure
T10240 18681-18683 IN denotes of
T10241 18684-18691 JJ denotes ectopic
T10242 18692-18696 NN denotes WWOX
T10243 18697-18699 IN denotes in
T10244 18700-18708 VB denotes inducing
T10245 18709-18718 NN denotes apoptosis
T10246 18719-18721 IN denotes of
T10247 18722-18728 NN denotes glioma
T10248 18729-18734 NN denotes cells
T10249 18735-18745 VB denotes possessing
T10250 18746-18750 JJ denotes wild
T10251 18751-18755 NN denotes type
T10252 18756-18759 NN denotes p53
T10253 18760-18762 VB denotes is
T10254 18763-18770 JJ denotes unusual
T10255 18771-18772 -LRB- denotes (
T10256 18772-18778 NNP denotes Chiang
T10257 18779-18781 FW denotes et
T10258 18782-18785 FW denotes al.
T10259 18785-18786 -COMMA- denotes ,
T10260 18787-18791 CD denotes 2012
T10261 18791-18792 -RRB- denotes )
T10262 18794-18796 IN denotes In
T10263 18797-18801 JJ denotes most
T10264 18802-18807 NN denotes cases
T10265 18807-18808 -COMMA- denotes ,
T10266 18809-18811 PRP denotes we
T10267 18812-18816 VB denotes have
T10268 18817-18822 VB denotes shown
T10269 18823-18827 IN denotes that
T10270 18828-18831 NN denotes p53
T10271 18832-18844 RB denotes functionally
T10272 18845-18854 VB denotes interacts
T10273 18855-18859 IN denotes with
T10274 18860-18864 NN denotes WWOX
T10275 18864-18865 -COMMA- denotes ,
T10276 18866-18869 CC denotes and
T10277 18870-18874 DT denotes both
T10278 18875-18883 NN denotes proteins
T10279 18884-18890 VB denotes induce
T10280 18891-18900 NN denotes apoptosis
T10281 18901-18903 IN denotes in
T10282 18904-18905 DT denotes a
T10283 18906-18917 JJ denotes synergistic
T10284 18918-18924 NN denotes manner
T10285 18925-18926 -LRB- denotes (
T10286 18926-18931 NNP denotes Chang
T10287 18932-18934 FW denotes et
T10288 18935-18938 FW denotes al.
T10289 18938-18939 -COMMA- denotes ,
T10290 18940-18944 CD denotes 2001
T10291 18944-18945 -COMMA- denotes ,
T10292 18946-18950 CD denotes 2003
T10293 18950-18951 -COMMA- denotes ,
T10294 18952-18957 NN denotes 2005a
T10295 18957-18958 -COMMA- denotes ,
T10296 18958-18959 NN denotes b
T10297 18959-18960 -COMMA- denotes ,
T10298 18961-18965 CD denotes 2007
T10299 18965-18966 -COMMA- denotes ,
T10300 18967-18971 CD denotes 2010
T10301 18971-18972 -COMMA- denotes ,
T10302 18973-18977 CD denotes 2012
T10303 18977-18978 -COLON- denotes ;
T10304 18979-18981 NNP denotes Su
T10305 18982-18984 FW denotes et
T10306 18985-18988 FW denotes al.
T10307 18988-18989 -COMMA- denotes ,
T10308 18990-18994 CD denotes 2012
T10309 18994-18995 -RRB- denotes )
T10310 18997-18998 DT denotes A
T10311 18999-19005 JJ denotes likely
T10312 19006-19014 NN denotes scenario
T10313 19015-19017 VB denotes is
T10314 19018-19022 IN denotes that
T10315 19023-19034 JJ denotes p53-binding
T10316 19035-19043 NN denotes proteins
T10317 19043-19044 -COMMA- denotes ,
T10318 19045-19050 WDT denotes which
T10319 19051-19054 VB denotes are
T10320 19055-19062 JJ denotes present
T10321 19063-19065 IN denotes in
T10322 19066-19070 NN denotes GBMs
T10323 19070-19071 -COMMA- denotes ,
T10324 19072-19075 MD denotes may
T10325 19076-19085 VB denotes interfere
T10326 19086-19090 IN denotes with
T10327 19091-19094 DT denotes the
T10328 19095-19104 JJ denotes apoptotic
T10329 19105-19113 NN denotes function
T10330 19114-19116 IN denotes of
T10331 19117-19121 NN denotes WWOX
T10332 19122-19125 CC denotes and
T10333 19126-19129 NN denotes p53
T10334 19131-19141 JJ denotes Functional
T10335 19142-19152 NN denotes antagonism
T10336 19153-19158 IN denotes among
T10337 19159-19164 NN denotes tumor
T10338 19165-19176 NN denotes suppressors
T10339 19177-19180 VB denotes has
T10340 19181-19186 RB denotes never
T10341 19187-19191 VB denotes been
T10342 19192-19202 VB denotes documented
T10343 19203-19205 IN denotes in
T10344 19206-19209 DT denotes the
T10345 19210-19220 NN denotes literature
T10346 19222-19229 RB denotes However
T10347 19229-19230 -COMMA- denotes ,
T10348 19231-19233 PRP denotes it
T10349 19234-19236 VB denotes is
T10350 19237-19240 RB denotes not
T10351 19241-19251 JJ denotes surprising
T10352 19252-19254 TO denotes to
T10353 19255-19259 VB denotes find
T10354 19260-19264 IN denotes that
T10355 19265-19269 JJ denotes many
T10356 19270-19275 NN denotes tumor
T10357 19276-19286 NN denotes suppressor
T10358 19287-19295 NN denotes proteins
T10359 19295-19296 -COMMA- denotes ,
T10360 19297-19301 FW denotes e.g.
T10361 19301-19302 -COMMA- denotes ,
T10362 19303-19306 NN denotes p53
T10363 19306-19307 -COMMA- denotes ,
T10364 19308-19312 NN denotes WWOX
T10365 19312-19313 -COMMA- denotes ,
T10366 19314-19319 NN denotes Smad4
T10367 19319-19320 -COMMA- denotes ,
T10368 19321-19325 NN denotes PTEN
T10369 19325-19326 -COMMA- denotes ,
T10370 19327-19331 NN denotes PP2A
T10371 19331-19332 -COMMA- denotes ,
T10372 19333-19336 CC denotes and
T10373 19337-19341 FW denotes etc.
T10374 19341-19342 -COMMA- denotes ,
T10375 19343-19346 VB denotes are
T10376 19347-19360 RB denotes significantly
T10377 19361-19372 VB denotes upregulated
T10378 19373-19379 IN denotes during
T10379 19380-19383 DT denotes the
T10380 19384-19389 JJ denotes early
T10381 19390-19395 NN denotes stage
T10382 19396-19398 IN denotes of
T10383 19399-19405 NN denotes cancer
T10384 19406-19417 NN denotes progression
T10385 19418-19419 -LRB- denotes (
T10386 19419-19422 NNP denotes Lai
T10387 19423-19425 FW denotes et
T10388 19426-19429 FW denotes al.
T10389 19429-19430 -COMMA- denotes ,
T10390 19431-19435 CD denotes 2005
T10391 19435-19436 -COLON- denotes ;
T10392 19437-19442 NNP denotes Chang
T10393 19443-19445 FW denotes et
T10394 19446-19449 FW denotes al.
T10395 19449-19450 -COMMA- denotes ,
T10396 19451-19462 JJ denotes unpublished
T10397 19462-19463 -RRB- denotes )
T10398 19465-19467 VB denotes Do
T10399 19468-19473 DT denotes these
T10400 19474-19482 NN denotes proteins
T10401 19483-19486 VB denotes act
T10402 19487-19502 RB denotes synergistically
T10403 19503-19505 IN denotes in
T10404 19506-19514 VB denotes blocking
T10405 19515-19521 NN denotes cancer
T10406 19522-19533 NN denotes progression
T10407 19534-19537 CC denotes but
T10408 19538-19542 VB denotes lose
T10409 19543-19550 NN denotes control
T10410 19551-19561 RB denotes eventually
T10411 19563-19565 CC denotes Or
T10412 19565-19566 -COMMA- denotes ,
T10413 19567-19569 VB denotes do
T10414 19570-19574 PRP denotes they
T10415 19575-19585 VB denotes counteract
T10416 19586-19590 DT denotes each
T10417 19591-19598 NN denotes other’s
T10418 19599-19607 NN denotes function
T10419 19607-19608 -COMMA- denotes ,
T10420 19609-19613 RB denotes thus
T10421 19614-19622 VB denotes allowing
T10422 19623-19629 NN denotes cancer
T10423 19630-19636 NN denotes growth
T10424 19638-19645 IN denotes Whether
T10425 19646-19656 JJ denotes endogenous
T10426 19657-19661 NN denotes WWOX
T10427 19662-19673 VB denotes counteracts
T10428 19674-19678 IN denotes with
T10429 19679-19682 DT denotes the
T10430 19683-19691 NN denotes function
T10431 19692-19694 IN denotes of
T10432 19695-19705 JJ denotes endogenous
T10433 19706-19709 NN denotes p53
T10434 19710-19712 VB denotes is
T10435 19713-19720 JJ denotes unknown
T10436 19721-19724 CC denotes and
T10437 19725-19732 VB denotes remains
T10438 19733-19735 TO denotes to
T10439 19736-19738 VB denotes be
T10440 19739-19750 VB denotes established
T10441 19752-19755 CD denotes One
T10442 19756-19758 IN denotes of
T10443 19759-19762 DT denotes the
T10444 19763-19769 JJ denotes unique
T10445 19770-19785 NN denotes characteristics
T10446 19786-19789 IN denotes for
T10447 19790-19799 JJ denotes malignant
T10448 19800-19807 NN denotes gliomas
T10449 19808-19810 VB denotes is
T10450 19811-19816 PRP-DOLLAR- denotes their
T10451 19817-19824 JJ denotes diffuse
T10452 19825-19837 NN denotes infiltration
T10453 19838-19842 IN denotes into
T10454 19843-19850 JJ denotes distant
T10455 19851-19856 NN denotes brain
T10456 19857-19863 NN denotes tissue
T10457 19865-19871 NN denotes Signal
T10458 19872-19880 NN denotes pathways
T10459 19880-19881 -COMMA- denotes ,
T10460 19882-19891 VB denotes involving
T10461 19892-19896 NN denotes PI3K
T10462 19896-19897 -COMMA- denotes ,
T10463 19898-19901 NN denotes Akt
T10464 19901-19902 -COMMA- denotes ,
T10465 19903-19907 NN denotes mTOR
T10466 19907-19908 -COMMA- denotes ,
T10467 19909-19914 NN denotes NF-κB
T10468 19914-19915 -COMMA- denotes ,
T10469 19916-19919 CC denotes and
T10470 19920-19929 NN denotes autophagy
T10471 19929-19930 -COMMA- denotes ,
T10472 19931-19934 VB denotes are
T10473 19935-19943 VB denotes believed
T10474 19944-19946 TO denotes to
T10475 19947-19953 VB denotes confer
T10476 19954-19959 DT denotes these
T10477 19960-19969 VB denotes migrating
T10478 19970-19975 NN denotes cells
T10479 19976-19985 JJ denotes resistant
T10480 19986-19988 TO denotes to
T10481 19989-19998 JJ denotes apoptotic
T10482 19999-20004 NN denotes death
T10483 20005-20006 -LRB- denotes (
T10484 20006-20013 NNP denotes Lefranc
T10485 20014-20016 FW denotes et
T10486 20017-20020 FW denotes al.
T10487 20020-20021 -COMMA- denotes ,
T10488 20022-20026 CD denotes 2005
T10489 20026-20027 -RRB- denotes )
T10490 20029-20035 NN denotes Glioma
T10491 20036-20041 NN denotes cells
T10492 20042-20049 VB denotes possess
T10493 20050-20054 NN denotes CD44
T10494 20055-20057 IN denotes as
T10495 20058-20059 DT denotes a
T10496 20060-20068 NN denotes receptor
T10497 20069-20072 IN denotes for
T10498 20073-20084 VB denotes interacting
T10499 20085-20089 IN denotes with
T10500 20090-20095 NN denotes brain
T10501 20096-20102 NN denotes matrix
T10502 20103-20113 NN denotes hyaluronan
T10503 20114-20115 -LRB- denotes (
T10504 20115-20120 NNP denotes Murai
T10505 20121-20123 FW denotes et
T10506 20124-20127 FW denotes al.
T10507 20127-20128 -COMMA- denotes ,
T10508 20129-20133 CD denotes 2004
T10509 20133-20134 -COLON- denotes ;
T10510 20135-20142 NNP denotes Yoshida
T10511 20143-20145 FW denotes et
T10512 20146-20149 FW denotes al.
T10513 20149-20150 -COMMA- denotes ,
T10514 20151-20155 CD denotes 2012
T10515 20155-20156 -RRB- denotes )
T10516 20156-20157 -COMMA- denotes ,
T10517 20158-20161 CC denotes and
T10518 20162-20169 JJ denotes secrete
T10519 20170-20184 NN denotes hyaluronidases
T10520 20185-20188 CC denotes and
T10521 20189-20207 NN denotes metalloproteinases
T10522 20208-20210 TO denotes to
T10523 20211-20221 VB denotes facilitate
T10524 20222-20227 PRP-DOLLAR- denotes their
T10525 20228-20237 NN denotes migration
T10526 20238-20239 -LRB- denotes (
T10527 20239-20246 NNP denotes Delpech
T10528 20247-20249 FW denotes et
T10529 20250-20253 FW denotes al.
T10530 20253-20254 -COMMA- denotes ,
T10531 20255-20259 CD denotes 2002
T10532 20259-20260 -COLON- denotes ;
T10533 20261-20267 NNP denotes Junker
T10534 20268-20270 FW denotes et
T10535 20271-20274 FW denotes al.
T10536 20274-20275 -COMMA- denotes ,
T10537 20276-20280 CD denotes 2003
T10538 20280-20281 -COLON- denotes ;
T10539 20282-20290 NNP denotes Hagemann
T10540 20291-20293 FW denotes et
T10541 20294-20297 FW denotes al.
T10542 20297-20298 -COMMA- denotes ,
T10543 20299-20303 CD denotes 2012
T10544 20303-20304 -RRB- denotes )
T10545 20306-20310 RB denotes Also
T10546 20310-20311 -COMMA- denotes ,
T10547 20312-20316 NN denotes lack
T10548 20317-20319 IN denotes of
T10549 20320-20324 NN denotes WWOX
T10550 20325-20335 NN denotes expression
T10551 20336-20338 VB denotes is
T10552 20339-20347 VB denotes expected
T10553 20348-20350 TO denotes to
T10554 20351-20358 VB denotes enhance
T10555 20359-20363 NN denotes cell
T10556 20364-20373 NN denotes migration
T10557 20375-20378 IN denotes For
T10558 20379-20386 NN denotes example
T10559 20386-20387 -COMMA- denotes ,
T10560 20388-20392 NN denotes loss
T10561 20393-20395 IN denotes of
T10562 20396-20400 NN denotes WWOX
T10563 20401-20412 VB denotes facilitates
T10564 20413-20422 NN denotes migration
T10565 20423-20425 IN denotes of
T10566 20426-20433 JJ denotes ovarian
T10567 20434-20440 NN denotes cancer
T10568 20441-20444 CC denotes and
T10569 20445-20457 NN denotes osteosarcoma
T10570 20458-20463 NN denotes cells
T10571 20464-20465 -LRB- denotes (
T10572 20465-20472 NNP denotes Gourley
T10573 20473-20475 FW denotes et
T10574 20476-20479 FW denotes al.
T10575 20479-20480 -COMMA- denotes ,
T10576 20481-20485 CD denotes 2009
T10577 20485-20486 -COLON- denotes ;
T10578 20487-20490 NNP denotes Del
T10579 20491-20495 NNP denotes Mare
T10580 20496-20498 FW denotes et
T10581 20499-20502 FW denotes al.
T10582 20502-20503 -COMMA- denotes ,
T10583 20504-20508 CD denotes 2011
T10584 20508-20509 -RRB- denotes )
T10585 20511-20518 JJ denotes Ectopic
T10586 20519-20529 NN denotes expression
T10587 20530-20532 IN denotes of
T10588 20533-20538 NN denotes TIAF1
T10589 20539-20540 -LRB- denotes (
T10590 20540-20553 JJ denotes TGF-β-induced
T10591 20554-20567 JJ denotes antiapoptotic
T10592 20568-20574 NN denotes factor
T10593 20574-20575 -RRB- denotes )
T10594 20575-20576 -COMMA- denotes ,
T10595 20577-20580 NN denotes p53
T10596 20580-20581 -COMMA- denotes ,
T10597 20582-20585 CC denotes and
T10598 20586-20590 NN denotes WWOX
T10599 20591-20601 VB denotes suppresses
T10600 20602-20623 JJ denotes anchorage-independent
T10601 20624-20630 NN denotes growth
T10602 20631-20634 CC denotes and
T10603 20635-20639 NN denotes cell
T10604 20640-20649 NN denotes migration
T10605 20650-20653 CC denotes and
T10606 20654-20660 VB denotes causes
T10607 20661-20670 NN denotes apoptosis
T10608 20671-20673 IN denotes in
T10609 20674-20680 NN denotes cancer
T10610 20681-20686 NN denotes cells
T10611 20687-20688 -LRB- denotes (
T10612 20688-20693 NNP denotes Chang
T10613 20694-20696 FW denotes et
T10614 20697-20700 FW denotes al.
T10615 20700-20701 -COMMA- denotes ,
T10616 20702-20706 CD denotes 2012
T10617 20706-20707 -RRB- denotes )
T10618 20709-20711 PRP denotes We
T10619 20712-20719 VB denotes believe
T10620 20720-20724 IN denotes that
T10621 20725-20731 NN denotes glioma
T10622 20732-20737 NN denotes cells
T10623 20737-20738 -COMMA- denotes ,
T10624 20739-20743 IN denotes with
T10625 20744-20748 NN denotes stem
T10626 20749-20758 JJ denotes cell-like
T10627 20759-20769 NN denotes properties
T10628 20769-20770 -COMMA- denotes ,
T10629 20771-20778 VB denotes migrate
T10630 20779-20791 RB denotes individually
T10631 20792-20798 RB denotes rather
T10632 20799-20803 IN denotes than
T10633 20804-20816 RB denotes collectively
T10634 20818-20822 DT denotes This
T10635 20823-20833 NN denotes assumption
T10636 20834-20836 VB denotes is
T10637 20837-20842 VB denotes based
T10638 20843-20847 IN denotes upon
T10639 20848-20851 PRP-DOLLAR- denotes our
T10640 20852-20864 NN denotes observations
T10641 20865-20869 IN denotes that
T10642 20870-20875 NN denotes mouse
T10643 20876-20880 NN denotes Wwox
T10644 20881-20885 NN denotes gene
T10645 20886-20894 NN denotes knockout
T10646 20895-20900 NN denotes cells
T10647 20901-20902 -LRB- denotes (
T10648 20902-20906 FW denotes e.g.
T10649 20906-20907 -COMMA- denotes ,
T10650 20908-20917 JJ denotes embryonic
T10651 20918-20929 NN denotes fibroblasts
T10652 20929-20930 -RRB- denotes )
T10653 20931-20938 VB denotes migrate
T10654 20939-20951 RB denotes individually
T10655 20952-20955 CC denotes and
T10656 20956-20968 RB denotes aggressively
T10657 20970-20972 IN denotes In
T10658 20973-20981 NN denotes contrast
T10659 20981-20982 -COMMA- denotes ,
T10660 20983-20987 JJ denotes wild
T10661 20988-20992 NN denotes type
T10662 20993-20998 NN denotes cells
T10663 20999-21006 VB denotes migrate
T10664 21007-21019 RB denotes collectively
T10665 21020-21021 -LRB- denotes (
T10666 21021-21025 NNP denotes Chou
T10667 21026-21028 FW denotes et
T10668 21029-21032 FW denotes al.
T10669 21032-21033 -COMMA- denotes ,
T10670 21034-21045 JJ denotes unpublished
T10671 21045-21046 -RRB- denotes )
T10672 21048-21053 IN denotes While
T10673 21054-21055 DT denotes a
T10674 21056-21063 NN denotes portion
T10675 21064-21066 IN denotes of
T10676 21067-21071 NN denotes WWOX
T10677 21072-21074 VB denotes is
T10678 21075-21083 VB denotes anchored
T10679 21084-21086 IN denotes on
T10680 21087-21090 DT denotes the
T10681 21091-21095 NN denotes cell
T10682 21096-21117 NN denotes membrane/cytoskeleton
T10683 21117-21118 -COMMA- denotes ,
T10684 21119-21132 JJ denotes WWOX-negative
T10685 21133-21138 NN denotes cells
T10686 21139-21143 VB denotes lose
T10687 21144-21155 NN denotes recognition
T10688 21156-21158 IN denotes by
T10689 21159-21167 JJ denotes parental
T10690 21168-21181 JJ denotes WWOX-positive
T10691 21182-21187 NN denotes cells
T10692 21187-21188 -COMMA- denotes ,
T10693 21189-21192 CC denotes and
T10694 21193-21197 DT denotes this
T10695 21198-21207 VB denotes increases
T10696 21208-21211 DT denotes the
T10697 21212-21220 NN denotes mobility
T10698 21221-21223 IN denotes of
T10699 21224-21237 JJ denotes WWOX-negative
T10700 21238-21243 NN denotes cells
T10701 21244-21246 TO denotes to
T10702 21247-21251 VB denotes move
T10703 21252-21256 RB denotes away
T10704 21257-21261 IN denotes from
T10705 21262-21265 DT denotes the
T10706 21266-21279 JJ denotes WWOX-positive
T10707 21280-21285 NN denotes cells
T10708 21287-21298 RB denotes Conceivably
T10709 21298-21299 -COMMA- denotes ,
T10710 21300-21313 JJ denotes WWOX-negative
T10711 21314-21320 NN denotes glioma
T10712 21321-21326 NN denotes cells
T10713 21327-21334 VB denotes migrate
T10714 21335-21347 RB denotes individually
T10715 21348-21351 CC denotes and
T10716 21352-21356 VB denotes turn
T10717 21357-21361 RP denotes away
T10718 21362-21366 IN denotes from
T10719 21367-21382 JJ denotes WWOX-expressing
T10720 21383-21388 NN denotes brain
T10721 21389-21394 NN denotes cells
T10722 21395-21397 TO denotes to
T10723 21398-21401 JJ denotes low
T10724 21402-21406 NN denotes WWOX
T10725 21407-21417 NN denotes expression
T10726 21418-21423 NN denotes areas
T10727 21425-21435 RB denotes Apparently
T10728 21435-21436 -COMMA- denotes ,
T10729 21437-21440 DT denotes the
T10730 21441-21450 JJ denotes migratory
T10731 21451-21459 NN denotes behavior
T10732 21460-21462 IN denotes of
T10733 21463-21476 JJ denotes WWOX-negative
T10734 21477-21483 NN denotes glioma
T10735 21484-21489 NN denotes cells
T10736 21490-21493 MD denotes may
T10737 21494-21501 VB denotes account
T10738 21502-21505 IN denotes for
T10739 21506-21509 DT denotes the
T10740 21510-21517 JJ denotes diffuse
T10741 21518-21526 NN denotes invasion
T10742 21527-21531 IN denotes into
T10743 21532-21539 JJ denotes distant
T10744 21540-21545 NN denotes brain
T10745 21546-21552 NN denotes tissue
T10746 21553-21554 -LRB- denotes (
T10747 21554-21558 NNP denotes Chou
T10748 21559-21561 FW denotes et
T10749 21562-21565 FW denotes al.
T10750 21565-21566 -COMMA- denotes ,
T10751 21567-21578 JJ denotes unpublished
T10752 21578-21579 -RRB- denotes )
T10753 21581-21590 JJ denotes Metabolic
T10754 21591-21602 NN denotes alterations
T10755 21603-21607 VB denotes have
T10756 21608-21612 VB denotes been
T10757 21613-21618 VB denotes shown
T10758 21619-21621 IN denotes in
T10759 21622-21626 NNP denotes Wwox
T10760 21627-21635 NN denotes knockout
T10761 21636-21640 NN denotes mice
T10762 21640-21641 -COMMA- denotes ,
T10763 21642-21651 VB denotes including
T10764 21652-21661 JJ denotes postnatal
T10765 21662-21671 NN denotes lethality
T10766 21671-21672 -COMMA- denotes ,
T10767 21673-21677 NN denotes bone
T10768 21678-21688 NN denotes metabolism
T10769 21689-21696 NN denotes defects
T10770 21696-21697 -COMMA- denotes ,
T10771 21698-21704 NN denotes ataxia
T10772 21704-21705 -COMMA- denotes ,
T10773 21706-21721 NN denotes steroidogenesis
T10774 21721-21722 -COMMA- denotes ,
T10775 21723-21726 CC denotes and
T10776 21727-21737 NN denotes generation
T10777 21738-21740 IN denotes of
T10778 21741-21754 NN denotes osteosarcomas
T10779 21755-21756 -LRB- denotes (
T10780 21756-21759 NNP denotes Del
T10781 21760-21764 NNP denotes Mare
T10782 21765-21767 FW denotes et
T10783 21768-21771 FW denotes al.
T10784 21771-21772 -COMMA- denotes ,
T10785 21773-21777 CD denotes 2011
T10786 21777-21778 -COLON- denotes ;
T10787 21779-21784 NNP denotes Salah
T10788 21785-21787 FW denotes et
T10789 21788-21791 FW denotes al.
T10790 21791-21792 -COMMA- denotes ,
T10791 21793-21797 CD denotes 2012
T10792 21797-21798 -RRB- denotes )
T10793 21800-21802 IN denotes In
T10794 21803-21804 DT denotes a
T10795 21805-21815 FW denotes Drosophila
T10796 21816-21821 NN denotes model
T10797 21821-21822 -COMMA- denotes ,
T10798 21823-21827 NNP denotes Wwox
T10799 21828-21830 VB denotes is
T10800 21831-21836 VB denotes shown
T10801 21837-21839 TO denotes to
T10802 21840-21851 VB denotes participate
T10803 21852-21854 IN denotes in
T10804 21855-21863 NN denotes pathways
T10805 21864-21873 VB denotes involving
T10806 21874-21881 JJ denotes aerobic
T10807 21882-21892 NN denotes metabolism
T10808 21893-21896 CC denotes and
T10809 21897-21906 JJ denotes oxidative
T10810 21907-21913 NN denotes stress
T10811 21914-21917 IN denotes for
T10812 21918-21928 NN denotes generation
T10813 21929-21931 IN denotes of
T10814 21932-21935 NN denotes ROS
T10815 21936-21937 -LRB- denotes (
T10816 21937-21944 NNP denotes O’Keefe
T10817 21945-21947 FW denotes et
T10818 21948-21951 FW denotes al.
T10819 21951-21952 -COMMA- denotes ,
T10820 21953-21957 CD denotes 2011
T10821 21957-21958 -RRB- denotes )
T10822 21960-21965 IN denotes Under
T10823 21966-21968 NN denotes UV
T10824 21969-21975 NN denotes stress
T10825 21975-21976 -COMMA- denotes ,
T10826 21977-21987 JJ denotes functional
T10827 21988-21992 NN denotes Wwox
T10828 21993-21997 NN denotes gene
T10829 21998-22008 NN denotes expression
T10830 22009-22016 VB denotes induces
T10831 22017-22020 NN denotes ROS
T10832 22021-22031 NN denotes production
T10833 22032-22034 IN denotes in
T10834 22035-22046 FW denotes Drosophila.
T10835 22047-22053 NN denotes Cancer
T10836 22054-22059 NN denotes cells
T10837 22060-22063 VB denotes are
T10838 22064-22069 VB denotes known
T10839 22070-22072 TO denotes to
T10840 22073-22079 RB denotes overly
T10841 22080-22087 VB denotes utilize
T10842 22088-22098 NN denotes glycolysis
T10843 22099-22102 IN denotes for
T10844 22103-22109 NN denotes growth
T10845 22110-22119 NN denotes advantage
T10846 22120-22121 VB denotes –
T10847 22122-22125 DT denotes the
T10848 22126-22135 JJ denotes so-called
T10849 22136-22143 NNP denotes Warburg
T10850 22144-22145 -LRB- denotes (
T10851 22145-22152 NNP denotes Moncada
T10852 22153-22155 FW denotes et
T10853 22156-22159 FW denotes al.
T10854 22159-22160 -COMMA- denotes ,
T10855 22161-22165 CD denotes 2012
T10856 22165-22166 -RRB- denotes )
T10857 22168-22179 RB denotes Conceivably
T10858 22179-22180 -COMMA- denotes ,
T10859 22181-22185 NN denotes WWOX
T10860 22186-22188 VB denotes is
T10861 22189-22195 JJ denotes likely
T10862 22196-22198 TO denotes to
T10863 22199-22207 VB denotes override
T10864 22208-22215 NN denotes glucose
T10865 22216-22227 NN denotes consumption
T10866 22228-22230 IN denotes in
T10867 22231-22237 NN denotes cancer
T10868 22238-22243 NN denotes cells
T10869 22244-22247 CC denotes and
T10870 22248-22254 VB denotes exerts
T10871 22255-22265 NN denotes generation
T10872 22266-22268 IN denotes of
T10873 22269-22272 NN denotes ROS
T10874 22273-22275 TO denotes to
T10875 22276-22280 VB denotes curb
T10876 22281-22284 DT denotes the
T10877 22285-22291 NN denotes cancer
T10878 22292-22296 NN denotes cell
T10879 22297-22303 NN denotes growth
T10880 22304-22307 CC denotes and
T10881 22308-22316 NN denotes invasion
T10882 22318-22320 IN denotes In
T10883 22321-22328 NN denotes summary
T10884 22328-22329 -COMMA- denotes ,
T10885 22330-22332 IN denotes in
T10886 22333-22337 DT denotes this
T10887 22338-22349 JJ denotes perspective
T10888 22350-22357 NN denotes article
T10889 22358-22360 PRP denotes we
T10890 22361-22365 VB denotes have
T10891 22366-22375 VB denotes discussed
T10892 22376-22379 DT denotes the
T10893 22380-22389 JJ denotes potential
T10894 22390-22394 NN denotes role
T10895 22395-22397 IN denotes of
T10896 22398-22403 NN denotes tumor
T10897 22404-22415 NN denotes suppressors
T10898 22416-22419 NN denotes p53
T10899 22420-22423 CC denotes and
T10900 22424-22428 NN denotes WWOX
T10901 22429-22431 IN denotes in
T10902 22432-22442 VB denotes regulating
T10903 22443-22446 NN denotes TMZ
T10904 22447-22458 NN denotes sensitivity
T10905 22459-22461 IN denotes in
T10906 22462-22465 NN denotes GBM
T10907 22466-22471 NN denotes cells
T10908 22473-22475 PRP denotes We
T10909 22476-22480 VB denotes have
T10910 22481-22486 VB denotes shown
T10911 22487-22490 DT denotes the
T10912 22491-22495 NN denotes role
T10913 22496-22498 IN denotes of
T10914 22499-22503 NN denotes WWOX
T10915 22504-22506 IN denotes in
T10916 22507-22518 VB denotes controlling
T10917 22519-22523 NN denotes cell
T10918 22524-22533 NN denotes migration
T10919 22534-22537 CC denotes and
T10920 22538-22547 JJ denotes metabolic
T10921 22548-22559 NN denotes alterations
T10922 22559-22560 -COMMA- denotes ,
T10923 22561-22564 CC denotes and
T10924 22565-22574 VB denotes discussed
T10925 22575-22578 DT denotes the
T10926 22579-22586 NN denotes effects
T10927 22587-22589 IN denotes of
T10928 22590-22594 NN denotes WWOX
T10929 22595-22605 NN denotes deficiency
T10930 22606-22609 CC denotes and
T10931 22610-22613 NN denotes TMZ
T10932 22614-22624 NN denotes resistance
T10933 22625-22627 IN denotes in
T10934 22628-22634 NN denotes cancer
T10935 22635-22640 NN denotes cells
T12472 22664-22671 NNP denotes Ming-Fu
T12473 22672-22678 NNP denotes Chiang
T12474 22679-22682 CC denotes and
T12475 22683-22689 NNP denotes Chun-I
T12476 22690-22693 NNP denotes Sze
T12477 22694-22699 VB denotes wrote
T12478 22700-22703 DT denotes the
T12479 22704-22712 NN denotes sections
T12480 22713-22720 VB denotes dealing
T12481 22721-22725 IN denotes with
T12482 22726-22729 NN denotes TMZ
T12483 22729-22730 -COLON- denotes ;
T12484 22731-22737 NNP denotes Pei-Yi
T12485 22738-22742 NNP denotes Chou
T12486 22743-22748 VB denotes wrote
T12487 22749-22752 DT denotes the
T12488 22753-22759 NN denotes review
T12489 22760-22768 NN denotes sections
T12490 22769-22772 IN denotes for
T12491 22773-22776 NN denotes p53
T12492 22777-22780 CC denotes and
T12493 22781-22785 NN denotes WWOX
T12494 22786-22789 CC denotes and
T12495 22790-22798 VB denotes designed
T12496 22799-22805 NN denotes graphs
T12497 22805-22806 -COLON- denotes ;
T12498 22807-22814 NNP denotes Wan-Jen
T12499 22815-22819 NNP denotes Wang
T12500 22820-22827 VB denotes managed
T12501 22828-22837 NN denotes citations
T12502 22837-22838 -COLON- denotes ;
T12503 22839-22847 NNP denotes Nan-Shan
T12504 22848-22853 NNP denotes Chang
T12505 22854-22863 VB denotes conceived
T12506 22864-22869 NN denotes ideas
T12507 22869-22870 -COMMA- denotes ,
T12508 22871-22876 VB denotes wrote
T12509 22877-22880 CC denotes and
T12510 22881-22891 RB denotes thoroughly
T12511 22892-22899 VB denotes revised
T12512 22900-22903 DT denotes the
T12513 22904-22914 NN denotes manuscript
T12514 22914-22915 -COMMA- denotes ,
T12515 22916-22919 CC denotes and
T12516 22920-22929 VB denotes discussed
T12517 22930-22934 IN denotes with
T12518 22935-22944 NN denotes coauthors
T12591 22978-22981 DT denotes The
T12592 22982-22989 NN denotes authors
T12593 22990-22997 VB denotes declare
T12594 22998-23002 IN denotes that
T12595 23003-23006 DT denotes the
T12596 23007-23015 NN denotes research
T12597 23016-23019 VB denotes was
T12598 23020-23029 VB denotes conducted
T12599 23030-23032 IN denotes in
T12600 23033-23036 DT denotes the
T12601 23037-23044 NN denotes absence
T12602 23045-23047 IN denotes of
T12603 23048-23051 DT denotes any
T12604 23052-23062 JJ denotes commercial
T12605 23063-23065 CC denotes or
T12606 23066-23075 JJ denotes financial
T12607 23076-23089 NN denotes relationships
T12608 23090-23094 WDT denotes that
T12609 23095-23100 MD denotes could
T12610 23101-23103 VB denotes be
T12611 23104-23113 VB denotes construed
T12612 23114-23116 IN denotes as
T12613 23117-23118 DT denotes a
T12614 23119-23128 JJ denotes potential
T12615 23129-23137 NN denotes conflict
T12616 23138-23140 IN denotes of
T12617 23141-23149 NN denotes interest
R100 T237 T234 arg2Of cells,in
R1000 T1450 T1449 arg1Of survival,patient
R1001 T1454 T1453 arg2Of microRNA-21,overexpressed
R1002 T1454 T1455 arg1Of microRNA-21,reduces
R1003 T1455 T1451 arg1Of reduces,Intriguingly
R1004 T1455 T1452 arg1Of reduces,","
R1005 T1455 T1461 arg1Of reduces,","
R1006 T1455 T1463 modOf reduces,blocking
R1007 T1457 T1456 arg1Of ratio,Bax/Bcl-2
R1008 T1457 T1458 arg1Of ratio,and
R1009 T1458 T1455 arg2Of and,reduces
R101 T237 T235 arg1Of cells,malignant
R1010 T1460 T1458 arg2Of activity,and
R1011 T1460 T1459 arg1Of activity,caspase-3
R1012 T1463 T1462 arg1Of blocking,thereby
R1013 T1465 T1463 arg2Of apoptosis,blocking
R1014 T1465 T1464 arg1Of apoptosis,TMZ-induced
R1015 T1465 T1466 arg1Of apoptosis,(
R1016 T1467 T1466 arg2Of Shi,(
R1017 T1467 T1468 arg1Of Shi,et
R1018 T1467 T1469 arg1Of Shi,al.
R1019 T1467 T1470 arg1Of Shi,","
R102 T237 T236 arg1Of cells,cancer
R1020 T1471 T1470 arg2Of 2010,","
R1021 T1472 T1466 arg3Of ),(
R1022 T1473 T1474 arg1Of MicroRNA-21,is
R1023 T1473 T1475 arg2Of MicroRNA-21,considered
R1024 T1475 T1474 arg2Of considered,is
R1025 T1475 T1476 arg1Of considered,as
R1026 T1479 T1476 arg2Of factor,as
R1027 T1479 T1477 arg1Of factor,a
R1028 T1479 T1478 arg1Of factor,pro-survival
R1029 T1479 T1480 arg1Of factor,for
R103 T237 T238 arg1Of cells,due
R1030 T1482 T1480 arg2Of cells,for
R1031 T1482 T1481 arg1Of cells,cancer
R1032 T1482 T1483 arg1Of cells,(
R1033 T1484 T1483 arg2Of Li,(
R1034 T1484 T1485 arg1Of Li,et
R1035 T1484 T1486 arg1Of Li,al.
R1036 T1484 T1487 arg1Of Li,","
R1037 T1488 T1487 arg2Of 2012,","
R1038 T1489 T1483 arg3Of ),(
R1039 T1490 T1491 arg1Of Integrins,play
R104 T241 T240 arg1Of hypermethylation,promoter
R1040 T1491 T1494 arg1Of play,in
R1041 T1491 T1502 arg1Of play,and
R1042 T1493 T1491 arg2Of role,play
R1043 T1493 T1492 arg1Of role,a
R1044 T1496 T1494 arg2Of resistance,in
R1045 T1496 T1495 arg1Of resistance,the
R1046 T1496 T1497 arg1Of resistance,of
R1047 T1496 T1500 arg1Of resistance,to
R1048 T1499 T1497 arg2Of cancers,of
R1049 T1499 T1498 arg1Of cancers,advanced
R105 T241 T242 arg1Of hypermethylation,","
R1050 T1501 T1500 arg2Of radiotherapy,to
R1051 T1502 T1511 arg1Of and,and
R1052 T1505 T1503 arg1Of integrin,chemotherapy.
R1053 T1505 T1504 arg1Of integrin,α5β1
R1054 T1505 T1507 arg1Of integrin,regulates
R1055 T1507 T1502 arg2Of regulates,and
R1056 T1507 T1506 arg1Of regulates,negatively
R1057 T1509 T1507 arg2Of signaling,regulates
R1058 T1509 T1508 arg1Of signaling,p53
R1059 T1511 T1510 arg1Of and,","
R106 T242 T246 arg1Of ",",and
R1060 T1513 T1512 arg1Of event,the
R1061 T1513 T1514 arg1Of event,induces
R1062 T1514 T1511 arg2Of induces,and
R1063 T1517 T1514 arg2Of resistance,induces
R1064 T1517 T1515 arg1Of resistance,glioma
R1065 T1517 T1516 arg1Of resistance,cell
R1066 T1517 T1518 arg1Of resistance,to
R1067 T1519 T1518 arg2Of TMZ,to
R1068 T1519 T1520 arg1Of TMZ,(
R1069 T1519 T1529 modOf TMZ,ri
R107 T244 T242 arg2Of alterations,","
R1070 T1521 T1520 arg2Of Janouskova,(
R1071 T1521 T1522 arg1Of Janouskova,et
R1072 T1521 T1523 arg1Of Janouskova,al.
R1073 T1521 T1524 arg1Of Janouskova,","
R1074 T1525 T1524 arg2Of 2012,","
R1075 T1526 T1520 arg3Of ),(
R1076 T1528 T1527 arg1Of β1 integ,. α5
R1077 T1528 T1529 arg1Of β1 integ,ri
R1078 T1528 T1530 arg2Of β1 integ,n is consi
R1079 T1530 T1529 arg2Of n is consi,ri
R108 T244 T243 arg1Of alterations,genetic
R1080 T1530 T1531 arg1Of n is consi,de
R1081 T1534 T1531 arg2Of rapeut,de
R1082 T1534 T1532 arg1Of rapeut,r
R1083 T1534 T1533 arg1Of rapeut,ed as a the
R1084 T1534 T1535 arg1Of rapeut,ic
R1085 T1538 T1535 arg2Of grade ,ic
R1086 T1538 T1536 arg1Of grade ,target for
R1087 T1538 T1537 arg1Of grade ,high-
R1088 T1544 T1539 arg1Of alkylpurine-DNA-N-glycosylase,The
R1089 T1544 T1540 arg1Of alkylpurine-DNA-N-glycosylase,base
R109 T246 T239 arg2Of and,to
R1090 T1544 T1541 arg1Of alkylpurine-DNA-N-glycosylase,excision
R1091 T1544 T1542 arg1Of alkylpurine-DNA-N-glycosylase,repair
R1092 T1544 T1543 arg1Of alkylpurine-DNA-N-glycosylase,enzyme
R1093 T1544 T1545 arg1Of alkylpurine-DNA-N-glycosylase,(
R1094 T1544 T1548 arg1Of alkylpurine-DNA-N-glycosylase,","
R1095 T1544 T1549 arg1Of alkylpurine-DNA-N-glycosylase,which
R1096 T1544 T1550 arg1Of alkylpurine-DNA-N-glycosylase,repairs
R1097 T1544 T1559 arg1Of alkylpurine-DNA-N-glycosylase,participates
R1098 T1546 T1545 arg2Of APNG,(
R1099 T1547 T1545 arg3Of ),(
R110 T246 T245 arg1Of and,","
R1100 T1554 T1555 arg1Of N3-methyladenine,and
R1101 T1555 T1550 arg2Of and,repairs
R1102 T1555 T1551 arg1Of and,the
R1103 T1555 T1552 arg1Of and,cytotoxic
R1104 T1555 T1553 arg1Of and,lesions
R1105 T1556 T1555 arg2Of N7-methylguanine,and
R1106 T1559 T1557 arg1Of participates,","
R1107 T1559 T1558 arg1Of participates,also
R1108 T1559 T1560 arg1Of participates,in
R1109 T1559 T1564 arg1Of participates,(
R111 T248 T246 arg2Of blockade,and
R1110 T1563 T1560 arg2Of resistance,in
R1111 T1563 T1561 arg1Of resistance,the
R1112 T1563 T1562 arg1Of resistance,TMZ
R1113 T1565 T1564 arg2Of Agnihotri,(
R1114 T1565 T1566 arg1Of Agnihotri,et
R1115 T1565 T1567 arg1Of Agnihotri,al.
R1116 T1565 T1568 arg1Of Agnihotri,","
R1117 T1569 T1568 arg2Of 2012,","
R1118 T1570 T1564 arg3Of ),(
R1119 T1571 T1572 arg1Of Upregulation,of
R112 T248 T247 arg1Of blockade,translational
R1120 T1571 T1577 modOf Upregulation,to
R1121 T1571 T1593 arg1Of Upregulation,contributes
R1122 T1576 T1572 arg2Of coupling,of
R1123 T1576 T1573 arg1Of coupling,mitochondrial
R1124 T1576 T1574 arg1Of coupling,respiratory
R1125 T1576 T1575 arg1Of coupling,chain
R1126 T1578 T1577 arg1Of suppress,to
R1127 T1580 T1578 arg2Of production,suppress
R1128 T1580 T1579 arg1Of production,the
R1129 T1580 T1581 arg1Of production,of
R113 T252 T251 arg1Of expression,ectopic
R1130 T1584 T1581 arg2Of species,of
R1131 T1584 T1582 arg1Of species,reactive
R1132 T1584 T1583 arg1Of species,oxygen
R1133 T1584 T1585 arg1Of species,(
R1134 T1584 T1588 arg2Of species,regulated
R1135 T1586 T1585 arg2Of ROS,(
R1136 T1587 T1585 arg3Of ),(
R1137 T1592 T1588 arg1Of oxidase,regulated
R1138 T1592 T1589 arg2Of oxidase,by
R1139 T1592 T1590 arg1Of oxidase,cytochrome
R114 T252 T253 arg1Of expression,of
R1140 T1592 T1591 arg1Of oxidase,c
R1141 T1593 T1594 arg1Of contributes,in
R1142 T1593 T1596 arg1Of contributes,to
R1143 T1595 T1594 arg2Of part,in
R1144 T1598 T1596 arg2Of resistance,to
R1145 T1598 T1597 arg1Of resistance,TMZ
R1146 T1598 T1599 arg1Of resistance,in
R1147 T1600 T1599 arg2Of gliomas,in
R1148 T1600 T1601 arg1Of gliomas,(
R1149 T1602 T1601 arg2Of Oliva,(
R115 T252 T258 arg1Of expression,induces
R1150 T1602 T1603 arg1Of Oliva,et
R1151 T1602 T1604 arg1Of Oliva,al.
R1152 T1602 T1605 arg1Of Oliva,","
R1153 T1606 T1605 arg2Of 2011,","
R1154 T1607 T1601 arg3Of ),(
R1155 T1608 T1609 arg1Of Reversal,of
R1156 T1608 T1612 arg1Of Reversal,may
R1157 T1608 T1613 arg1Of Reversal,be
R1158 T1608 T1614 arg2Of Reversal,achieved
R1159 T1611 T1609 arg2Of resistance,of
R116 T256 T253 arg2Of WWOX,of
R1160 T1611 T1610 arg1Of resistance,TMZ
R1161 T1614 T1612 arg2Of achieved,may
R1162 T1614 T1613 arg2Of achieved,be
R1163 T1617 T1614 arg1Of pseudosubstrates,achieved
R1164 T1617 T1615 arg2Of pseudosubstrates,by
R1165 T1617 T1616 arg1Of pseudosubstrates,MGMT
R1166 T1617 T1618 arg1Of pseudosubstrates,","
R1167 T1619 T1620 arg1Of O6-benzylguanine,and
R1168 T1620 T1618 arg2Of and,","
R1169 T1620 T1622 modOf and,to
R117 T256 T254 arg1Of WWOX,wild
R1170 T1621 T1620 arg2Of lomeguatrib,and
R1171 T1623 T1622 arg1Of sensitize,to
R1172 T1624 T1623 arg2Of tumors,sensitize
R1173 T1624 T1625 arg1Of tumors,to
R1174 T1626 T1625 arg2Of TMZ,to
R1175 T1626 T1627 arg1Of TMZ,(
R1176 T1628 T1627 arg2Of Zhang,(
R1177 T1628 T1629 arg1Of Zhang,et
R1178 T1628 T1630 arg1Of Zhang,al.
R1179 T1628 T1631 arg1Of Zhang,","
R118 T256 T255 arg1Of WWOX,type
R1180 T1632 T1631 arg2Of 2012b,","
R1181 T1633 T1627 arg3Of ),(
R1182 T1634 T1635 arg1Of Methoxyamine-blocker,of
R1183 T1634 T1639 arg1Of Methoxyamine-blocker,contributes
R1184 T1638 T1635 arg2Of repair,of
R1185 T1638 T1636 arg1Of repair,base
R1186 T1638 T1637 arg1Of repair,excision
R1187 T1639 T1640 arg1Of contributes,significantly
R1188 T1639 T1641 arg1Of contributes,to
R1189 T1639 T1645 arg1Of contributes,when
R119 T258 T249 arg1Of induces,Intriguingly
R1190 T1643 T1641 arg2Of cytotoxicity,to
R1191 T1643 T1642 arg1Of cytotoxicity,TMZ
R1192 T1645 T1644 arg1Of when,particularly
R1193 T1647 T1646 arg1Of adducts,O6-methylguanine
R1194 T1647 T1648 arg1Of adducts,are
R1195 T1647 T1649 arg2Of adducts,repaired
R1196 T1647 T1651 arg2Of adducts,tolerated
R1197 T1649 T1650 arg1Of repaired,or
R1198 T1650 T1645 arg2Of or,when
R1199 T1650 T1648 arg2Of or,are
R120 T258 T250 arg1Of induces,","
R1200 T1650 T1652 arg1Of or,(
R1201 T1651 T1650 arg2Of tolerated,or
R1202 T1653 T1652 arg2Of Goellner,(
R1203 T1653 T1654 arg1Of Goellner,et
R1204 T1653 T1655 arg1Of Goellner,al.
R1205 T1653 T1656 arg1Of Goellner,","
R1206 T1653 T1658 arg1Of Goellner,;
R1207 T1657 T1656 arg2Of 2011,","
R1208 T1659 T1658 arg2Of Zhang,;
R1209 T1659 T1660 arg1Of Zhang,et
R121 T258 T257 arg1Of induces,preferentially
R1210 T1659 T1661 arg1Of Zhang,al.
R1211 T1659 T1662 arg1Of Zhang,","
R1212 T1663 T1662 arg2Of 2012b,","
R1213 T1664 T1652 arg3Of ),(
R1214 T1666 T1665 arg1Of targeting,Dual
R1215 T1666 T1667 arg1Of targeting,of
R1216 T1670 T1668 arg1Of repair,base
R1217 T1670 T1669 arg1Of repair,excision
R1218 T1670 T1671 arg1Of repair,and
R1219 T1671 T1667 arg2Of and,of
R122 T258 T260 arg1Of induces,in
R1220 T1672 T1671 arg2Of NAD,and
R1221 T1672 T1673 arg1Of NAD,(
R1222 T1674 T1673 arg2Of +,(
R1223 T1675 T1673 arg3Of ),(
R1224 T1676 T1666 arg1Of biosynthesis,targeting
R1225 T1676 T1677 arg1Of biosynthesis,may
R1226 T1676 T1678 arg1Of biosynthesis,reverse
R1227 T1678 T1677 arg2Of reverse,may
R1228 T1680 T1678 arg2Of resistance,reverse
R1229 T1680 T1679 arg1Of resistance,TMZ
R123 T259 T258 arg2Of apoptosis,induces
R1230 T1680 T1681 arg1Of resistance,in
R1231 T1680 T1683 arg1Of resistance,with
R1232 T1682 T1681 arg2Of patients,in
R1233 T1684 T1685 arg1Of resistant,and
R1234 T1686 T1685 arg2Of recurrent,and
R1235 T1687 T1683 arg2Of GBM,with
R1236 T1687 T1684 arg1Of GBM,resistant
R1237 T1687 T1686 arg1Of GBM,recurrent
R1238 T1687 T1688 arg1Of GBM,(
R1239 T1689 T1688 arg2Of Goellner,(
R124 T263 T260 arg2Of cells,in
R1240 T1689 T1690 arg1Of Goellner,et
R1241 T1689 T1691 arg1Of Goellner,al.
R1242 T1689 T1692 arg1Of Goellner,","
R1243 T1693 T1692 arg2Of 2011,","
R1244 T1694 T1688 arg3Of ),(
R1245 T1695 T1696 arg1Of Interferon-β,(
R1246 T1695 T1699 arg1Of Interferon-β,","
R1247 T1697 T1696 arg2Of IFN-β,(
R1248 T1698 T1696 arg3Of ),(
R1249 T1699 T1704 arg1Of ",",","
R125 T263 T261 arg1Of cells,human
R1250 T1700 T1699 arg2Of levetiracetam,","
R1251 T1700 T1701 arg1Of levetiracetam,(
R1252 T1702 T1701 arg2Of LEV,(
R1253 T1703 T1701 arg3Of ),(
R1254 T1704 T1707 arg1Of ",",and
R1255 T1705 T1704 arg2Of resveratrol,","
R1256 T1707 T1706 arg1Of and,","
R1257 T1707 T1713 arg1Of and,increase
R1258 T1709 T1707 arg2Of acid,and
R1259 T1709 T1708 arg1Of acid,valproic
R126 T263 T262 arg1Of cells,glioblastoma
R1260 T1709 T1710 arg1Of acid,(
R1261 T1711 T1710 arg2Of VAP,(
R1262 T1712 T1710 arg3Of ),(
R1263 T1713 T1718 arg1Of increase,through
R1264 T1713 T1723 arg1Of increase,(
R1265 T1715 T1713 arg2Of sensitivity,increase
R1266 T1715 T1714 arg1Of sensitivity,the
R1267 T1715 T1716 arg1Of sensitivity,of
R1268 T1717 T1716 arg2Of TMZ,of
R1269 T1719 T1720 arg1Of MGMT-dependent,or
R127 T263 T264 arg1Of cells,harboring
R1270 T1721 T1720 arg2Of -independent,or
R1271 T1722 T1718 arg2Of mechanisms,through
R1272 T1722 T1719 arg1Of mechanisms,MGMT-dependent
R1273 T1722 T1721 arg1Of mechanisms,-independent
R1274 T1724 T1723 arg2Of Nakada,(
R1275 T1724 T1725 arg1Of Nakada,et
R1276 T1724 T1726 arg1Of Nakada,al.
R1277 T1724 T1727 arg1Of Nakada,","
R1278 T1728 T1727 arg2Of 2012,","
R1279 T1729 T1723 arg3Of ),(
R128 T266 T264 arg2Of p53,harboring
R1280 T1730 T1731 arg1Of Resveratrol,","
R1281 T1730 T1736 arg1Of Resveratrol,reverses
R1282 T1734 T1731 arg2Of polyphenol,","
R1283 T1734 T1732 arg1Of polyphenol,a
R1284 T1734 T1733 arg1Of polyphenol,natural
R1285 T1736 T1735 arg1Of reverses,","
R1286 T1736 T1739 arg1Of reverses,via
R1287 T1736 T1743 arg1Of reverses,(
R1288 T1738 T1736 arg2Of resistance,reverses
R1289 T1738 T1737 arg1Of resistance,TMZ
R129 T266 T265 arg1Of p53,mutant
R1290 T1742 T1739 arg2Of mechanism,via
R1291 T1742 T1740 arg1Of mechanism,an
R1292 T1742 T1741 arg1Of mechanism,NF-κB-dependent
R1293 T1744 T1743 arg2Of Huang,(
R1294 T1744 T1745 arg1Of Huang,et
R1295 T1744 T1746 arg1Of Huang,al.
R1296 T1744 T1747 arg1Of Huang,","
R1297 T1748 T1747 arg2Of 2012,","
R1298 T1749 T1743 arg3Of ),(
R1299 T1751 T1750 arg1Of inhibitor,STAT3
R130 T267 T268 arg1Of WWOX,is
R1300 T1751 T1752 arg1Of inhibitor,or
R1301 T1752 T1755 arg1Of or,potentiates
R1302 T1754 T1752 arg2Of knockdown,or
R1303 T1754 T1753 arg1Of knockdown,STAT3
R1304 T1757 T1755 arg2Of efficacy,potentiates
R1305 T1757 T1756 arg1Of efficacy,TMZ
R1306 T1757 T1758 arg1Of efficacy,in
R1307 T1762 T1758 arg2Of lines,in
R1308 T1785 T1783 arg2Of resistance,of
R1309 T1785 T1784 arg1Of resistance,TMZ
R131 T267 T269 arg2Of WWOX,known
R1310 T1787 T1786 arg2Of hyperoxia,Induced
R1311 T1787 T1788 arg1Of hyperoxia,can
R1312 T1787 T1789 arg1Of hyperoxia,be
R1313 T1787 T1790 arg2Of hyperoxia,utilized
R1314 T1762 T1759 arg1Of lines,resistant
R1315 T1762 T1760 arg1Of lines,GBM
R1316 T1790 T1788 arg2Of utilized,can
R1317 T1790 T1789 arg2Of utilized,be
R1318 T1762 T1761 arg1Of lines,cell
R1319 T1762 T1763 arg1Of lines,(
R132 T267 T272 arg1Of WWOX,bind
R1320 T1792 T1790 arg3Of reverse,utilized
R1321 T1792 T1791 arg1Of reverse,to
R1322 T1764 T1763 arg2Of Kohsaka,(
R1323 T1794 T1792 arg2Of resistance,reverse
R1324 T1794 T1793 arg1Of resistance,TMZ
R1325 T1794 T1795 arg1Of resistance,in
R1326 T1796 T1795 arg2Of GBMs,in
R1327 T1796 T1797 arg1Of GBMs,(
R1328 T1764 T1765 arg1Of Kohsaka,et
R1329 T1798 T1797 arg2Of Sun,(
R133 T267 T274 arg1Of WWOX,stabilize
R1330 T1798 T1799 arg1Of Sun,et
R1331 T1798 T1800 arg1Of Sun,al.
R1332 T1798 T1801 arg1Of Sun,","
R1333 T1764 T1766 arg1Of Kohsaka,al.
R1334 T1764 T1767 arg1Of Kohsaka,","
R1335 T1768 T1767 arg2Of 2012,","
R1336 T1802 T1801 arg2Of 2012,","
R1337 T1803 T1797 arg3Of ),(
R1338 T1806 T1804 arg1Of cells,Cancer
R1339 T1806 T1805 arg1Of cells,stem
R134 T269 T268 arg2Of known,is
R1340 T1806 T1807 arg1Of cells,are
R1341 T1807 T1808 arg1Of are,probably
R1342 T1769 T1763 arg3Of ),(
R1343 T1810 T1807 arg2Of key,are
R1344 T1810 T1809 arg1Of key,the
R1345 T1810 T1811 arg1Of key,to
R1346 T1810 T1813 arg1Of key,in
R1347 T1771 T1770 arg1Of hypoxia,Intratumoral
R1348 T1812 T1811 arg2Of failure,to
R1349 T1815 T1813 arg2Of treatment,in
R135 T272 T273 arg1Of bind,and
R1350 T1815 T1814 arg1Of treatment,TMZ
R1351 T1817 T1816 arg1Of concept,The
R1352 T1817 T1818 arg1Of concept,of
R1353 T1817 T1823 arg1Of concept,from
R1354 T1817 T1831 arg1Of concept,has
R1355 T1817 T1832 arg1Of concept,been
R1356 T1817 T1834 arg2Of concept,complicated
R1357 T1817 T1837 arg2Of concept,thought
R1358 T1771 T1772 arg1Of hypoxia,is
R1359 T1771 T1773 arg1Of hypoxia,common
R136 T273 T269 arg3Of and,known
R1360 T1771 T1777 arg1Of hypoxia,may
R1361 T1771 T1778 arg1Of hypoxia,be
R1362 T1771 T1779 arg2Of hypoxia,associated
R1363 T1822 T1818 arg2Of survival,of
R1364 T1822 T1819 arg1Of survival,cancer
R1365 T1822 T1820 arg1Of survival,stem
R1366 T1822 T1821 arg1Of survival,cell
R1367 T1772 T1774 arg1Of is,in
R1368 T1824 T1823 arg2Of treatment,from
R1369 T1824 T1825 arg1Of treatment,with
R137 T273 T270 arg1Of and,to
R1370 T1826 T1827 arg1Of TMZ,and
R1371 T1772 T1776 arg1Of is,and
R1372 T1827 T1825 arg2Of and,with
R1373 T1773 T1772 arg2Of common,is
R1374 T1830 T1827 arg2Of drugs,and
R1375 T1830 T1828 arg1Of drugs,other
R1376 T1830 T1829 arg1Of drugs,chemotherapeutic
R1377 T1775 T1774 arg2Of GBMs,in
R1378 T1834 T1835 arg1Of complicated,than
R1379 T1835 T1831 arg2Of than,has
R138 T273 T271 arg1Of and,physically
R1380 T1835 T1832 arg2Of than,been
R1381 T1835 T1833 arg1Of than,more
R1382 T1779 T1776 arg2Of associated,and
R1383 T1837 T1835 arg2Of thought,than
R1384 T1837 T1836 arg1Of thought,previously
R1385 T1837 T1838 arg1Of thought,(
R1386 T1839 T1838 arg2Of Beier,(
R1387 T1839 T1840 arg1Of Beier,et
R1388 T1839 T1841 arg1Of Beier,al.
R1389 T1839 T1842 arg1Of Beier,","
R139 T274 T273 arg2Of stabilize,and
R1390 T1839 T1844 arg1Of Beier,;
R1391 T1843 T1842 arg2Of 2011,","
R1392 T1779 T1777 arg2Of associated,may
R1393 T1779 T1778 arg2Of associated,be
R1394 T1845 T1844 arg2Of Chen,;
R1395 T1779 T1780 arg1Of associated,with
R1396 T1782 T1780 arg2Of development,with
R1397 T1845 T1846 arg1Of Chen,et
R1398 T1845 T1847 arg1Of Chen,al.
R1399 T1845 T1848 arg1Of Chen,","
R140 T277 T272 arg2Of p53,bind
R1400 T1849 T1848 arg2Of 2012,","
R1401 T1850 T1838 arg3Of ),(
R1402 T1782 T1781 arg1Of development,the
R1403 T1854 T1851 arg1Of cells,CD133-positive
R1404 T1854 T1852 arg1Of cells,cancer
R1405 T1854 T1853 arg1Of cells,stem
R1406 T1854 T1855 arg1Of cells,are
R1407 T1854 T1856 arg2Of cells,expressed
R1408 T1856 T1855 arg2Of expressed,are
R1409 T1856 T1857 arg1Of expressed,in
R141 T277 T274 arg2Of p53,stabilize
R1410 T1856 T1866 arg1Of expressed,(
R1411 T1782 T1783 arg1Of development,of
R1412 T1886 T1882 arg2Of cells,for
R1413 T1861 T1859 arg1Of cells,normal
R1414 T1861 T1860 arg1Of cells,stem
R1415 T1861 T1862 arg1Of cells,and
R1416 T1862 T1857 arg2Of and,in
R1417 T1862 T1858 arg1Of and,both
R1418 T1865 T1862 arg2Of cells,and
R1419 T1865 T1863 arg1Of cells,cancer
R142 T277 T275 arg1Of p53,wild
R1420 T1865 T1864 arg1Of cells,stem
R1421 T1867 T1868 arg1Of Donovan,and
R1422 T1868 T1866 arg2Of and,(
R1423 T1868 T1870 arg1Of and,","
R1424 T1869 T1868 arg2Of Pilkington,and
R1425 T1871 T1870 arg2Of 2012,","
R1426 T1872 T1866 arg3Of ),(
R1427 T1886 T1883 arg1Of cells,glioma
R1428 T1886 T1884 arg1Of cells,cancer
R1429 T1886 T1885 arg1Of cells,stem
R143 T277 T276 arg1Of p53,type
R1430 T1886 T1887 arg1Of cells,relative
R1431 T1876 T1875 arg1Of role,the
R1432 T1876 T1877 arg1Of role,of
R1433 T1876 T1879 arg1Of role,as
R1434 T1876 T1892 arg1Of role,has
R1435 T1876 T1895 arg1Of role,be
R1436 T1876 T1896 arg2Of role,established
R1437 T1878 T1877 arg2Of CD133,of
R1438 T1887 T1888 arg1Of relative,to
R1439 T1891 T1888 arg2Of function,to
R144 T280 T281 arg1Of we,provide
R1440 T1881 T1879 arg2Of marker,as
R1441 T1881 T1880 arg1Of marker,a
R1442 T1881 T1882 arg1Of marker,for
R1443 T1891 T1889 arg1Of function,its
R1444 T1891 T1890 arg1Of function,biological
R1445 T1892 T1873 arg1Of has,However
R1446 T1892 T1874 arg1Of has,","
R1447 T1892 T1893 arg1Of has,yet
R1448 T1896 T1892 arg2Of established,has
R1449 T1896 T1894 arg1Of established,to
R145 T280 T294 arg1Of we,postulate
R1453 T1896 T1895 arg2Of established,be
R146 T281 T293 arg1Of provide,and
R147 T283 T281 arg2Of overview,provide
R148 T283 T282 arg1Of overview,an
R149 T283 T284 arg1Of overview,for
R150 T287 T284 arg2Of knowledge,for
R151 T287 T285 arg1Of knowledge,the
R152 T287 T286 arg2Of knowledge,updated
R153 T287 T288 arg1Of knowledge,in
R154 T289 T290 arg1Of p53,and
R155 T290 T288 arg2Of and,in
R156 T291 T290 arg2Of WWOX,and
R157 T293 T278 arg1Of and,Here
R158 T293 T279 arg1Of and,","
R159 T293 T292 arg1Of and,","
R160 T294 T293 arg2Of postulate,and
R161 T296 T294 arg2Of scenarios,postulate
R162 T296 T295 arg1Of scenarios,potential
R163 T296 T297 arg1Of scenarios,that
R164 T299 T298 arg1Of type,wild
R165 T299 T300 arg1Of type,and
R166 T300 T304 arg1Of and,or
R167 T302 T300 arg2Of p53,and
R168 T302 T301 arg1Of p53,mutant
R169 T304 T303 arg1Of or,","
R170 T304 T307 arg1Of or,modulate
R171 T305 T304 arg2Of isoforms,or
R172 T307 T297 arg2Of modulate,that
R173 T307 T306 arg1Of modulate,","
R174 T310 T307 arg2Of function,modulate
R175 T310 T308 arg1Of function,the
R176 T310 T309 arg1Of function,apoptotic
R177 T310 T311 arg1Of function,of
R178 T312 T311 arg2Of WWOX,of
R179 T313 T314 arg1Of We,propose
R180 T318 T316 arg1Of activation,triggering
R181 T318 T317 arg1Of activation,WWOX
R182 T318 T319 arg1Of activation,by
R183 T318 T322 arg1Of activation,under
R184 T318 T326 arg1Of activation,is
R185 T318 T327 arg2Of activation,needed
R186 T321 T319 arg2Of drugs,by
R187 T321 T320 arg1Of drugs,therapeutic
R188 T325 T322 arg2Of deficiency,under
R189 T325 T323 arg1Of deficiency,p53
R190 T325 T324 arg1Of deficiency,functional
R191 T327 T314 arg2Of needed,propose
R192 T327 T315 arg1Of needed,that
R193 T327 T326 arg2Of needed,is
R194 T327 T328 modOf needed,to
R195 T329 T332 arg1Of overcome,and
R196 T331 T329 arg2Of resistance,overcome
R197 T331 T330 arg1Of resistance,TMZ
R198 T332 T328 arg1Of and,to
R199 T333 T332 arg2Of induce,and
R200 T336 T333 arg2Of death,induce
R201 T336 T334 arg1Of death,GBM
R202 T336 T335 arg1Of death,cell
R2748 T4151 T4152 arg1Of p53,and
R2749 T4152 T4149 arg1Of and,tumor
R2750 T4152 T4150 arg1Of and,suppressors
R2751 T4152 T4154 arg1Of and,were
R2752 T4152 T4155 arg2Of and,shown
R2753 T4152 T4157 arg1Of and,regulate
R2754 T4153 T4152 arg2Of WWOX,and
R2755 T4155 T4147 arg1Of shown,Recently
R2756 T4155 T4148 arg1Of shown,","
R2757 T4155 T4154 arg2Of shown,were
R2758 T4157 T4155 arg3Of regulate,shown
R2759 T4157 T4156 arg1Of regulate,to
R2760 T4157 T4163 arg1Of regulate,(
R2761 T4159 T4157 arg2Of apoptosis,regulate
R2762 T4159 T4158 arg1Of apoptosis,the
R2763 T4159 T4160 arg1Of apoptosis,of
R2764 T4162 T4160 arg2Of cells,of
R2765 T4162 T4161 arg1Of cells,glioblastoma
R2766 T4164 T4163 arg2Of Chiang,(
R2767 T4164 T4165 arg1Of Chiang,et
R2768 T4164 T4166 arg1Of Chiang,al.
R2769 T4164 T4167 arg1Of Chiang,","
R2770 T4168 T4167 arg2Of 2012,","
R2771 T4169 T4163 arg3Of ),(
R2772 T4172 T4170 arg1Of oxidoreductase,WW
R2773 T4172 T4171 arg1Of oxidoreductase,domain-containing
R2774 T4172 T4173 arg1Of oxidoreductase,","
R2775 T4172 T4174 arg2Of oxidoreductase,known
R2776 T4172 T4183 arg1Of oxidoreductase,is
R2777 T4172 T4184 arg2Of oxidoreductase,encoded
R2778 T4174 T4175 arg1Of known,as
R2779 T4176 T4177 arg1Of WWOX,","
R2780 T4177 T4180 arg1Of ",",or
R2781 T4178 T4177 arg2Of FOR,","
R2782 T4180 T4175 arg2Of or,as
R2783 T4180 T4179 arg1Of or,","
R2784 T4181 T4180 arg2Of WOX1,or
R2785 T4184 T4182 arg1Of encoded,","
R2786 T4184 T4183 arg2Of encoded,is
R2787 T4190 T4184 arg1Of gene,encoded
R2788 T4190 T4185 arg2Of gene,by
R2789 T4190 T4186 arg1Of gene,human
R2790 T4190 T4187 arg1Of gene,or
R2791 T4190 T4188 arg1Of gene,mouse
R2792 T4190 T4189 arg1Of gene,WWOX/Wwox
R2793 T4192 T4191 arg1Of gene,This
R2794 T4192 T4193 arg1Of gene,is
R2795 T4192 T4194 arg1Of gene,located
R2796 T4194 T4193 arg2Of located,is
R2797 T4194 T4195 arg1Of located,in
R2798 T4197 T4195 arg2Of 16q23.3–24.1,in
R2799 T4197 T4196 arg1Of 16q23.3–24.1,chromosome
R28 T168 T166 arg1Of WWOX,Tumor
R2800 T4197 T4198 arg1Of 16q23.3–24.1,","
R2801 T4200 T4198 arg2Of area,","
R2802 T4200 T4199 arg1Of area,an
R2803 T4200 T4201 arg2Of area,known
R2804 T4201 T4202 arg1Of known,as
R2805 T4207 T4202 arg2Of FRA16D,as
R2806 T4207 T4203 arg1Of FRA16D,the
R2807 T4207 T4204 arg1Of FRA16D,common
R2808 T4207 T4205 arg1Of FRA16D,fragile
R2809 T4207 T4206 arg1Of FRA16D,site
R2810 T4211 T4208 arg1Of protein,The
R2811 T4211 T4209 arg1Of protein,full-length
R2812 T4211 T4210 arg1Of protein,WWOX
R2813 T4211 T4212 arg1Of protein,is
R2814 T4211 T4213 arg2Of protein,composed
R2815 T4213 T4267 arg1Of composed,(
R2816 T4213 T4212 arg2Of composed,is
R2817 T4213 T4214 arg1Of composed,of
R2818 T4213 T4236 arg1Of composed,(
R2819 T4218 T4215 arg1Of domains,two
R2820 T4218 T4216 arg1Of domains,N-terminal
R2821 T4218 T4217 arg1Of domains,WW
R2822 T4218 T4219 arg1Of domains,","
R2823 T4218 T4230 arg1Of domains,and
R2824 T4226 T4225 arg2Of SDR,(
R2825 T4227 T4225 arg3Of ),(
R2826 T4228 T4219 arg2Of domain,","
R2827 T4228 T4220 arg1Of domain,a
R2828 T4228 T4221 arg1Of domain,C-terminal
R2829 T4228 T4222 arg1Of domain,short-chain
R2830 T4228 T4223 arg1Of domain,alcohol
R2831 T4228 T4224 arg1Of domain,dehydrogenase/reductase
R2832 T4228 T4225 arg1Of domain,(
R2833 T4230 T4214 arg2Of and,of
R2834 T4230 T4229 arg1Of and,","
R2835 T4235 T4230 arg2Of D3,and
R2836 T4235 T4231 arg1Of D3,a
R2837 T4235 T4232 arg1Of D3,proapoptotic
R2838 T4235 T4233 arg1Of D3,C-terminal
R2839 T4235 T4234 arg1Of D3,tail
R2840 T4237 T4238 arg1Of Chang,et
R2841 T4237 T4239 arg1Of Chang,al.
R2842 T4237 T4240 arg1Of Chang,","
R2843 T4240 T4242 arg1Of ",",","
R2844 T4241 T4240 arg2Of 2001,","
R2845 T4242 T4244 arg1Of ",",","
R2846 T4243 T4242 arg2Of 2007,","
R2847 T4244 T4246 arg1Of ",",;
R2848 T4245 T4244 arg2Of 2010,","
R2849 T4246 T4236 arg2Of ;,(
R2850 T4246 T4260 arg1Of ;,;
R2851 T4247 T4248 arg1Of Aqeilan,et
R2852 T4247 T4249 arg1Of Aqeilan,al.
R2853 T4247 T4250 arg1Of Aqeilan,","
R2854 T4250 T4252 arg1Of ",",","
R2855 T4251 T4250 arg2Of 2004,","
R2856 T4252 T4254 arg1Of ",",;
R2857 T4253 T4252 arg2Of 2007,","
R2858 T4254 T4246 arg2Of ;,;
R2859 T4255 T4256 arg1Of Hong,et
R2860 T4255 T4257 arg1Of Hong,al.
R2861 T4255 T4258 arg1Of Hong,","
R2862 T4258 T4254 arg2Of ",",;
R2863 T4259 T4258 arg2Of 2007,","
R2864 T4261 T4260 arg2Of Salah,;
R2865 T4261 T4262 arg1Of Salah,et
R2866 T4261 T4263 arg1Of Salah,al.
R2867 T4261 T4264 arg1Of Salah,","
R2868 T4265 T4264 arg2Of 2012,","
R2869 T4266 T4236 arg3Of ),(
R2870 T4268 T4267 arg2Of Figure,(
R2871 T4268 T4269 arg1Of Figure,1
R2872 T4270 T4267 arg3Of ),(
R2873 T4271 T4272 arg1Of WWOX,may
R2874 T4271 T4273 arg1Of WWOX,act
R2875 T4273 T4272 arg2Of act,may
R2876 T4273 T4274 arg1Of act,as
R2877 T4273 T4282 arg1Of act,","
R2878 T4273 T4283 arg1Of act,since
R2879 T4277 T4274 arg2Of receptor,as
R2880 T4277 T4275 arg1Of receptor,an
R2881 T4277 T4276 arg1Of receptor,alternative
R2882 T4277 T4278 arg1Of receptor,for
R2883 T4281 T4278 arg2Of hormones,for
R2884 T4281 T4279 arg1Of hormones,sex
R2885 T4281 T4280 arg1Of hormones,steroid
R2886 T4286 T4284 arg1Of domain,its
R2887 T4286 T4285 arg1Of domain,SDR
R2888 T4286 T4287 arg1Of domain,possesses
R2889 T4287 T4283 arg2Of possesses,since
R2890 T4290 T4287 arg2Of motif,possesses
R2891 T4290 T4288 arg1Of motif,an
R2892 T4290 T4289 arg1Of motif,NSYK
R2893 T4290 T4291 arg1Of motif,capable
R2894 T4291 T4292 arg1Of capable,of
R2895 T4293 T4292 arg2Of interacting,of
R2896 T4293 T4294 arg1Of interacting,with
R2897 T4293 T4298 arg1Of interacting,(
R2898 T4295 T4296 arg1Of androgen,and
R2899 T4296 T4294 arg2Of and,with
R29 T168 T167 arg1Of WWOX,Suppressor
R2900 T4297 T4296 arg2Of estrogen,and
R2901 T4299 T4298 arg2Of Chang,(
R2902 T4299 T4300 arg1Of Chang,et
R2903 T4299 T4301 arg1Of Chang,al.
R2904 T4299 T4302 arg1Of Chang,","
R2905 T4299 T4304 arg1Of Chang,;
R2906 T4303 T4302 arg2Of 2005a,","
R2907 T4305 T4304 arg2Of Su,;
R2908 T4305 T4306 arg1Of Su,et
R2909 T4305 T4307 arg1Of Su,al.
R2910 T4305 T4308 arg1Of Su,","
R2911 T4309 T4308 arg2Of 2012,","
R2912 T4310 T4298 arg3Of ),(
R2913 T4311 T4312 arg1Of Expression,of
R2914 T4311 T4314 arg1Of Expression,is
R2915 T4311 T4316 arg2Of Expression,altered
R2916 T4311 T4318 arg2Of Expression,lost
R2917 T4313 T4312 arg2Of WWOX,of
R2918 T4316 T4317 arg1Of altered,or
R2919 T4317 T4314 arg2Of or,is
R2920 T4317 T4315 arg1Of or,either
R2921 T4318 T4317 arg2Of lost,or
R2922 T4318 T4319 arg1Of lost,from
R2923 T4318 T4322 arg1Of lost,in
R2924 T4321 T4319 arg2Of modification,from
R2925 T4321 T4320 arg1Of modification,epigenetic
R2926 T4325 T4322 arg2Of cancers,in
R2927 T4325 T4323 arg1Of cancers,multiple
R2928 T4325 T4324 arg1Of cancers,malignant
R2929 T4325 T4326 arg1Of cancers,","
R2930 T4325 T4328 arg1Of cancers,as
R2931 T4328 T4327 arg1Of as,such
R2932 T4332 T4329 arg1Of carcinoma,non-small
R2933 T4332 T4330 arg1Of carcinoma,cell
R2934 T4332 T4331 arg1Of carcinoma,lung
R2935 T4332 T4333 arg1Of carcinoma,(
R2936 T4332 T4340 arg1Of carcinoma,","
R2937 T4334 T4333 arg2Of Donati,(
R2938 T4334 T4335 arg1Of Donati,et
R2939 T4334 T4336 arg1Of Donati,al.
R2940 T4334 T4337 arg1Of Donati,","
R2941 T4338 T4337 arg2Of 2007,","
R2942 T4339 T4333 arg3Of ),(
R2943 T4340 T4360 arg1Of ",",","
R2944 T4342 T4341 arg1Of malignancies,hematopoietic
R2945 T4342 T4343 arg1Of malignancies,(
R2946 T4342 T4350 arg1Of malignancies,","
R2947 T4344 T4345 arg1Of Ishii,and
R2948 T4345 T4343 arg2Of and,(
R2949 T4345 T4347 arg1Of and,","
R2950 T4346 T4345 arg2Of Furukawa,and
R2951 T4348 T4347 arg2Of 2004,","
R2952 T4349 T4343 arg3Of ),(
R2953 T4350 T4340 arg2Of ",",","
R2954 T4350 T4353 arg1Of ",",(
R2955 T4352 T4350 arg2Of carcinoma,","
R2956 T4352 T4351 arg1Of carcinoma,gastric
R2957 T4354 T4353 arg2Of Aqeilan,(
R2958 T4354 T4355 arg1Of Aqeilan,et
R2959 T4354 T4356 arg1Of Aqeilan,al.
R2960 T4354 T4357 arg1Of Aqeilan,","
R2961 T4358 T4357 arg2Of 2004,","
R2962 T4359 T4353 arg3Of ),(
R2963 T4360 T4373 arg1Of ",",(
R2964 T4360 T4387 arg1Of ",",and
R2965 T4362 T4361 arg1Of carcinoma,pancreatic
R2966 T4362 T4363 arg1Of carcinoma,(
R2967 T4362 T4370 arg1Of carcinoma,","
R2968 T4364 T4363 arg2Of Kuroki,(
R2969 T4364 T4365 arg1Of Kuroki,et
R2970 T4364 T4366 arg1Of Kuroki,al.
R2971 T4364 T4367 arg1Of Kuroki,","
R2972 T4368 T4367 arg2Of 2004,","
R2973 T4369 T4363 arg3Of ),(
R2974 T4370 T4360 arg2Of ",",","
R2975 T4372 T4370 arg2Of carcinoma,","
R2976 T4372 T4371 arg1Of carcinoma,breast
R2977 T4374 T4373 arg2Of Guler,(
R2978 T4374 T4375 arg1Of Guler,et
R2979 T4374 T4376 arg1Of Guler,al.
R2980 T4374 T4377 arg1Of Guler,","
R2981 T4374 T4379 arg1Of Guler,;
R2982 T4378 T4377 arg2Of 2004,","
R2983 T4380 T4379 arg2Of Aqeilan,;
R2984 T4380 T4381 arg1Of Aqeilan,et
R2985 T4380 T4382 arg1Of Aqeilan,al.
R2986 T4380 T4383 arg1Of Aqeilan,","
R2987 T4384 T4383 arg2Of 2007,","
R2988 T4385 T4373 arg3Of ),(
R2989 T4387 T4328 arg2Of and,as
R2990 T4387 T4386 arg1Of and,","
R2991 T4388 T4387 arg2Of glioblastoma,and
R2992 T4388 T4389 arg1Of glioblastoma,multiforme
R2993 T4388 T4390 arg1Of glioblastoma,(
R2994 T4391 T4390 arg2Of Kosla,(
R2995 T4391 T4392 arg1Of Kosla,et
R2996 T4391 T4393 arg1Of Kosla,al.
R2997 T4391 T4394 arg1Of Kosla,","
R2998 T4395 T4394 arg2Of 2011,","
R2999 T4396 T4390 arg3Of ),(
R30 T168 T169 arg1Of WWOX,and
R3000 T4397 T4398 arg1Of Restoration,of
R3001 T4397 T4401 arg1Of Restoration,prevents
R3002 T4400 T4398 arg2Of gene,of
R3003 T4400 T4399 arg1Of gene,WWOX
R3004 T4401 T4428 arg1Of prevents,(
R3005 T4403 T4404 arg1Of growth,of
R3006 T4403 T4407 arg1Of growth,(
R3007 T4403 T4414 arg1Of growth,","
R3008 T4406 T4404 arg2Of cancer,of
R3009 T4406 T4405 arg1Of cancer,lung
R3010 T4408 T4407 arg2Of Fabbri,(
R3011 T4408 T4409 arg1Of Fabbri,et
R3012 T4408 T4410 arg1Of Fabbri,al.
R3013 T4408 T4411 arg1Of Fabbri,","
R3014 T4412 T4411 arg2Of 2005,","
R3015 T4413 T4407 arg3Of ),(
R3016 T4414 T4401 arg2Of ",",prevents
R3017 T4414 T4402 arg1Of ",",the
R3018 T4416 T4415 arg1Of cancer,pancreatic
R3019 T4416 T4417 arg1Of cancer,(
R3020 T4416 T4425 arg1Of cancer,and
R3021 T4418 T4417 arg2Of Nakayama,(
R3022 T4418 T4419 arg1Of Nakayama,et
R3023 T4418 T4420 arg1Of Nakayama,al.
R3024 T4418 T4421 arg1Of Nakayama,","
R3025 T4422 T4421 arg2Of 2008,","
R3026 T4423 T4417 arg3Of ),(
R3027 T4425 T4414 arg2Of and,","
R3028 T4425 T4424 arg1Of and,","
R3029 T4427 T4425 arg2Of cancer,and
R3030 T4427 T4426 arg1Of cancer,prostate
R3031 T4429 T4428 arg2Of Hong,(
R3032 T4429 T4430 arg1Of Hong,et
R3033 T4429 T4431 arg1Of Hong,al.
R3034 T4429 T4432 arg1Of Hong,","
R3035 T4433 T4432 arg2Of 2009,","
R3036 T4434 T4428 arg3Of ),(
R3037 T4438 T4435 arg1Of domain,The
R3038 T4438 T4436 arg1Of domain,first
R3039 T4438 T4437 arg1Of domain,WW
R3040 T4438 T4439 arg1Of domain,of
R3041 T4438 T4441 arg1Of domain,may
R3042 T4438 T4442 arg1Of domain,interact
R3043 T4440 T4439 arg2Of WWOX,of
R3044 T4442 T4441 arg2Of interact,may
R3045 T4442 T4443 arg1Of interact,with
R3046 T4444 T4443 arg2Of proteins,with
R3047 T4444 T4445 arg1Of proteins,possessing
R3048 T4448 T4445 arg2Of motif,possessing
R3049 T4448 T4446 arg1Of motif,a
R3050 T4448 T4447 arg1Of motif,PPxY
R3051 T4448 T4449 arg1Of motif,(
R3052 T4448 T4453 arg1Of motif,as
R3053 T4450 T4449 arg2Of s,(
R3054 T4451 T4449 arg3Of ),(
R3055 T4453 T4452 arg1Of as,such
R3056 T4454 T4455 arg1Of AP-2γ,","
R3057 T4455 T4457 arg1Of ",",","
R3058 T4456 T4455 arg2Of p73,","
R3059 T4457 T4459 arg1Of ",",","
R3060 T4458 T4457 arg2Of ErbB4,","
R3061 T4459 T4461 arg1Of ",",","
R3062 T4460 T4459 arg2Of Ezrin,","
R3063 T4461 T4463 arg1Of ",",","
R3064 T4462 T4461 arg2Of SIMPLE,","
R3065 T4463 T4465 arg1Of ",",","
R3066 T4464 T4463 arg2Of c-Jun,","
R3067 T4465 T4468 arg1Of ",",and
R3068 T4466 T4465 arg2Of RUNX4,","
R3069 T4468 T4453 arg2Of and,as
R3070 T4468 T4467 arg1Of and,","
R3071 T4470 T4468 arg2Of others,and
R3072 T4470 T4469 arg1Of others,many
R3073 T4470 T4471 arg1Of others,(
R3074 T4472 T4471 arg2Of Chang,(
R3075 T4472 T4473 arg1Of Chang,et
R3076 T4472 T4474 arg1Of Chang,al.
R3077 T4472 T4475 arg1Of Chang,","
R3078 T4472 T4477 arg1Of Chang,;
R3079 T4476 T4475 arg2Of 2007,","
R3080 T4478 T4477 arg2Of Salah,;
R3081 T4478 T4479 arg1Of Salah,et
R3082 T4478 T4480 arg1Of Salah,al.
R3083 T4478 T4481 arg1Of Salah,","
R3084 T4478 T4483 arg1Of Salah,;
R3085 T4478 T4489 arg1Of Salah,;
R3086 T4482 T4481 arg2Of 2012,","
R3087 T4484 T4485 arg1Of Su,et
R3088 T4484 T4486 arg1Of Su,al.
R3089 T4484 T4487 arg1Of Su,","
R3090 T4487 T4483 arg2Of ",",;
R3091 T4488 T4487 arg2Of 2012,","
R3092 T4490 T4489 arg2Of Figure,;
R3093 T4490 T4491 arg1Of Figure,1
R3094 T4492 T4471 arg3Of ),(
R3095 T4495 T4493 arg1Of WWOX,Transiently
R3096 T4495 T4494 arg2Of WWOX,overexpressed
R3097 T4495 T4496 arg1Of WWOX,binds
R3098 T4495 T4506 arg1Of WWOX,block
R3099 T4496 T4505 arg1Of binds,and
R31 T169 T175 arg1Of and,in
R3100 T4498 T4497 arg1Of factors,transcription
R3101 T4499 T4500 arg1Of AP-2,","
R3102 T4500 T4503 arg1Of ",",and
R3103 T4501 T4500 arg2Of p73,","
R3104 T4503 T4496 arg2Of and,binds
R3105 T4503 T4498 arg1Of and,factors
R3106 T4503 T4502 arg1Of and,","
R3107 T4504 T4503 arg2Of c-Jun,and
R3108 T4505 T4512 arg1Of and,","
R3109 T4505 T4513 arg1Of and,which
R3110 T4505 T4514 arg1Of and,suppresses
R3111 T4506 T4505 arg2Of block,and
R3112 T4506 T4511 arg1Of block,vitro
R3113 T4509 T4506 arg2Of relocation,block
R3114 T4509 T4507 arg1Of relocation,their
R3115 T4509 T4508 arg1Of relocation,nuclear
R3116 T4511 T4510 arg1Of vitro,in
R3117 T4514 T4518 arg1Of suppresses,(
R3118 T4517 T4514 arg2Of survival,suppresses
R3119 T4517 T4515 arg1Of survival,cancer
R3120 T4517 T4516 arg1Of survival,cell
R3121 T4519 T4518 arg2Of Salah,(
R3122 T4519 T4520 arg1Of Salah,et
R3123 T4519 T4521 arg1Of Salah,al.
R3124 T4519 T4522 arg1Of Salah,","
R3125 T4523 T4522 arg2Of 2012,","
R3126 T4524 T4518 arg3Of ),(
R3127 T4527 T4525 arg2Of contrast,In
R3128 T4527 T4526 arg1Of contrast,stark
R3129 T4529 T4530 arg1Of Wwox,co-migrates
R3130 T4530 T4525 arg1Of co-migrates,In
R3131 T4530 T4528 arg1Of co-migrates,","
R3132 T4530 T4531 arg1Of co-migrates,with
R3133 T4532 T4533 arg1Of proapoptotic,and
R3134 T4534 T4533 arg2Of pro-survival,and
R3135 T4536 T4531 arg2Of factors,with
R3136 T4536 T4532 arg1Of factors,proapoptotic
R3137 T4536 T4534 arg1Of factors,pro-survival
R3138 T4536 T4535 arg1Of factors,transcription
R3139 T4536 T4537 arg1Of factors,to
R3140 T4539 T4537 arg2Of nuclei,to
R3141 T4539 T4538 arg1Of nuclei,the
R3142 T4539 T4540 arg1Of nuclei,of
R3143 T4541 T4540 arg2Of neurons,of
R3144 T4541 T4542 arg1Of neurons,upon
R3145 T4545 T4542 arg2Of axotomy,upon
R3146 T4545 T4543 arg1Of axotomy,sciatic
R3147 T4545 T4544 arg1Of axotomy,nerve
R3148 T4545 T4546 arg1Of axotomy,in
R3149 T4547 T4546 arg2Of rats,in
R3150 T4547 T4548 arg1Of rats,(
R3151 T4549 T4548 arg2Of Li,(
R3152 T4549 T4550 arg1Of Li,et
R3153 T4549 T4551 arg1Of Li,al.
R3154 T4549 T4552 arg1Of Li,","
R3155 T4553 T4552 arg2Of 2009,","
R3156 T4554 T4548 arg3Of ),(
R3157 T4556 T4555 arg1Of blocking,No
R3158 T4556 T4557 arg1Of blocking,of
R3159 T4556 T4562 arg1Of blocking,to
R3160 T4556 T4565 arg1Of blocking,by
R3161 T4556 T4567 arg1Of blocking,was
R3162 T4556 T4568 arg2Of blocking,observed
R3163 T4558 T4557 arg2Of translocation,of
R3164 T4558 T4559 arg1Of translocation,of
R3165 T4561 T4559 arg2Of factors,of
R3166 T4561 T4560 arg1Of factors,transcription
R3167 T4564 T4562 arg2Of nuclei,to
R3168 T4564 T4563 arg1Of nuclei,the
R3169 T4566 T4565 arg2Of Wwox,by
R3170 T4568 T4567 arg2Of observed,was
R3171 T4571 T4569 arg2Of conditions,Under
R3172 T4571 T4570 arg1Of conditions,stress
R3173 T4573 T4574 arg1Of WWOX,is
R3174 T4573 T4575 arg2Of WWOX,activated
R3175 T4573 T4582 arg1Of WWOX,binds
R3176 T4575 T4574 arg2Of activated,is
R3177 T4575 T4576 arg1Of activated,via
R3178 T4575 T4581 arg1Of activated,and
R3179 T4577 T4576 arg2Of phosphorylation,via
R3180 T4577 T4578 arg1Of phosphorylation,at
R3181 T4579 T4578 arg2Of Tyr33,at
R3182 T4581 T4569 arg1Of and,Under
R3183 T4581 T4572 arg1Of and,","
R3184 T4581 T4580 arg1Of and,","
R3185 T4582 T4581 arg2Of binds,and
R3186 T4582 T4584 arg1Of binds,independently
R3187 T4582 T4589 arg1Of binds,(
R3188 T4583 T4582 arg2Of proteins,binds
R3189 T4584 T4585 arg1Of independently,of
R3190 T4588 T4585 arg2Of motif,of
R3191 T4588 T4586 arg1Of motif,the
R3192 T4588 T4587 arg1Of motif,PPxY
R3193 T4590 T4591 arg1Of Chang,et
R3194 T4590 T4592 arg1Of Chang,al.
R3195 T4590 T4593 arg1Of Chang,","
R3196 T4593 T4595 arg1Of ",",","
R3197 T4594 T4593 arg2Of 2001,","
R3198 T4595 T4589 arg2Of ",",(
R3199 T4595 T4597 arg1Of ",",","
R32 T171 T170 arg1Of Alterations,p53
R3200 T4596 T4595 arg2Of 2003,","
R3201 T4598 T4599 arg1Of 2005a,","
R3202 T4599 T4601 arg1Of ",",","
R3203 T4600 T4599 arg2Of b,","
R3204 T4601 T4597 arg2Of ",",","
R3205 T4601 T4603 arg1Of ",",","
R3206 T4602 T4601 arg2Of 2007,","
R3207 T4604 T4603 arg2Of 2010,","
R3208 T4605 T4589 arg3Of ),(
R3209 T4607 T4606 arg2Of WWOX,Activated
R3210 T4607 T4609 arg1Of WWOX,interacts
R3211 T4609 T4608 arg1Of interacts,physically
R3212 T4609 T4610 arg1Of interacts,with
R3213 T4613 T4610 arg2Of p53,with
R3214 T4613 T4611 arg1Of p53,serine
R3215 T4613 T4612 arg1Of p53,46-phosphorylated
R3216 T4613 T4614 arg1Of p53,(
R3217 T4613 T4618 arg1Of p53,","
R3218 T4613 T4619 arg1Of p53,which
R3219 T4613 T4620 arg1Of p53,stabilizes
R3220 T4615 T4614 arg2Of Figure,(
R3221 T4615 T4616 arg1Of Figure,1
R3222 T4617 T4614 arg3Of ),(
R3223 T4620 T4626 arg1Of stabilizes,(
R3224 T4621 T4622 arg1Of p53,and
R3225 T4622 T4620 arg2Of and,stabilizes
R3226 T4625 T4622 arg2Of function,and
R3227 T4625 T4623 arg1Of function,its
R3228 T4625 T4624 arg1Of function,apoptotic
R3229 T4627 T4626 arg2Of Chang,(
R3230 T4627 T4628 arg1Of Chang,et
R3231 T4627 T4629 arg1Of Chang,al.
R3232 T4627 T4630 arg1Of Chang,","
R3233 T4631 T4630 arg2Of 2005b,","
R3234 T4632 T4626 arg3Of ),(
R3235 T4635 T4636 arg1Of WWOX,binds
R3236 T4636 T4633 arg1Of binds,Also
R3237 T4636 T4634 arg1Of binds,","
R3238 T4638 T4636 arg2Of proteins,binds
R3239 T4638 T4637 arg2Of proteins,Disheveled
R3240 T4638 T4639 arg1Of proteins,(
R3241 T4638 T4642 arg1Of proteins,","
R3242 T4638 T4643 arg1Of proteins,which
R3243 T4638 T4644 arg1Of proteins,are
R3244 T4640 T4639 arg2Of Dvl,(
R3245 T4641 T4639 arg3Of ),(
R3246 T4646 T4644 arg2Of components,are
R3247 T4646 T4645 arg1Of components,key
R3248 T4646 T4647 arg1Of components,in
R3249 T4650 T4647 arg2Of pathway,in
R3250 T4650 T4648 arg1Of pathway,Wnt/β-catenin
R3251 T4650 T4649 arg1Of pathway,signaling
R3252 T4650 T4651 arg1Of pathway,(
R3253 T4652 T4651 arg2Of Figure,(
R3254 T4652 T4653 arg1Of Figure,1
R3255 T4654 T4651 arg3Of ),(
R3256 T4657 T4655 arg1Of motif,No
R3257 T4657 T4656 arg1Of motif,PPxY
R3258 T4657 T4658 arg1Of motif,is
R3259 T4657 T4662 arg1Of motif,overexpressed
R3260 T4657 T4671 arg1Of motif,blocks
R3261 T4661 T4659 arg2Of Transiently,in
R3262 T4661 T4660 arg1Of Transiently,Dvl.
R3263 T4662 T4658 arg2Of overexpressed,is
R3264 T4662 T4659 arg1Of overexpressed,in
R3265 T4662 T4666 arg1Of overexpressed,in
R3266 T4662 T4669 arg1Of overexpressed,and
R3267 T4665 T4662 arg2Of Dvl-2,overexpressed
R3268 T4665 T4663 arg1Of Dvl-2,WWOX
R3269 T4665 T4664 arg1Of Dvl-2,sequesters
R3270 T4668 T4666 arg2Of cytoplasm,in
R3271 T4668 T4667 arg1Of cytoplasm,the
R3272 T4671 T4669 arg2Of blocks,and
R3273 T4671 T4670 arg1Of blocks,thereby
R3274 T4675 T4671 arg2Of activity,blocks
R3275 T4675 T4672 arg1Of activity,Dvl-2-mediated
R3276 T4675 T4673 arg1Of activity,TCF
R3277 T4675 T4674 arg1Of activity,transcriptional
R3278 T4675 T4676 arg1Of activity,(
R3279 T4677 T4676 arg2Of Bouteille,(
R3280 T4677 T4678 arg1Of Bouteille,et
R3281 T4677 T4679 arg1Of Bouteille,al.
R3282 T4677 T4680 arg1Of Bouteille,","
R3283 T4681 T4680 arg2Of 2009,","
R3284 T4682 T4676 arg3Of ),(
R3285 T4684 T4683 arg2Of WWOX,Overexpressed
R3286 T4684 T4685 arg1Of WWOX,induces
R3287 T4684 T4688 arg1Of WWOX,inhibits
R3288 T4685 T4687 arg1Of induces,and
R3289 T4686 T4685 arg2Of apoptosis,induces
R3290 T4688 T4687 arg2Of inhibits,and
R3291 T4688 T4707 arg1Of inhibits,(
R3292 T4689 T4690 arg1Of proliferation,of
R3293 T4689 T4702 arg1Of proliferation,and
R3294 T4694 T4690 arg2Of cells,of
R3295 T4694 T4691 arg1Of cells,human
R3296 T4694 T4692 arg1Of cells,hepatic
R3297 T4694 T4693 arg1Of cells,carcinoma
R3298 T4694 T4695 arg1Of cells,(
R3299 T4696 T4695 arg2Of Hu,(
R33 T171 T172 arg1Of Alterations,and
R3300 T4696 T4697 arg1Of Hu,et
R3301 T4696 T4698 arg1Of Hu,al.
R3302 T4696 T4699 arg1Of Hu,","
R3303 T4700 T4699 arg2Of 2012,","
R3304 T4701 T4695 arg3Of ),(
R3305 T4702 T4688 arg2Of and,inhibits
R3306 T4706 T4702 arg2Of types,and
R3307 T4706 T4703 arg1Of types,many
R3308 T4706 T4704 arg1Of types,cancer
R3309 T4706 T4705 arg1Of types,cell
R3310 T4708 T4709 arg1Of Chang,et
R3311 T4708 T4710 arg1Of Chang,al.
R3312 T4708 T4711 arg1Of Chang,","
R3313 T4711 T4713 arg1Of ",",","
R3314 T4712 T4711 arg2Of 2007,","
R3315 T4713 T4715 arg1Of ",",;
R3316 T4714 T4713 arg2Of 2010,","
R3317 T4715 T4707 arg2Of ;,(
R3318 T4715 T4721 arg1Of ;,;
R3319 T4716 T4717 arg1Of Salah,et
R3320 T4716 T4718 arg1Of Salah,al.
R3321 T4716 T4719 arg1Of Salah,","
R3322 T4719 T4715 arg2Of ",",;
R3323 T4720 T4719 arg2Of 2012,","
R3324 T4722 T4721 arg2Of Su,;
R3325 T4722 T4723 arg1Of Su,et
R3326 T4722 T4724 arg1Of Su,al.
R3327 T4722 T4725 arg1Of Su,","
R3328 T4726 T4725 arg2Of 2012,","
R3329 T4727 T4707 arg3Of ),(
R3330 T4728 T4729 arg1Of WWOX,enhances
R3331 T4728 T4738 arg1Of WWOX,down-regulating
R3332 T4728 T4745 arg1Of WWOX,up-regulating
R3333 T4729 T4737 arg1Of enhances,by
R3334 T4732 T4729 arg2Of function,enhances
R3335 T4732 T4730 arg1Of function,the
R3336 T4732 T4731 arg1Of function,cytotoxic
R3337 T4732 T4733 arg1Of function,of
R3338 T4736 T4733 arg2Of factor,of
R3339 T4736 T4734 arg1Of factor,tumor
R3340 T4736 T4735 arg1Of factor,necrosis
R3341 T4738 T4744 arg1Of down-regulating,and
R3342 T4741 T4742 arg1Of Bcl-2,and
R3343 T4742 T4738 arg2Of and,down-regulating
R3344 T4742 T4739 arg1Of and,apoptosis
R3345 T4742 T4740 arg1Of and,inhibitor
R3346 T4743 T4742 arg2Of Bcl-xL,and
R3347 T4744 T4737 arg2Of and,by
R3348 T4745 T4744 arg2Of up-regulating,and
R3349 T4745 T4748 arg1Of up-regulating,(
R3350 T4747 T4745 arg2Of p53,up-regulating
R3351 T4747 T4746 arg1Of p53,apoptotic
R3352 T4749 T4748 arg2Of Chang,(
R3353 T4749 T4750 arg1Of Chang,et
R3354 T4749 T4751 arg1Of Chang,al.
R3355 T4749 T4752 arg1Of Chang,","
R3356 T4753 T4752 arg2Of 2001,","
R3357 T4754 T4748 arg3Of ),(
R3358 T4757 T4758 arg1Of WWOX,mediates
R3359 T4758 T4755 arg1Of mediates,Also
R3360 T4758 T4756 arg1Of mediates,","
R3361 T4758 T4761 arg1Of mediates,synergistically
R3362 T4758 T4762 arg1Of mediates,with
R3363 T4760 T4758 arg2Of death,mediates
R3364 T4760 T4759 arg1Of death,cell
R3365 T4763 T4762 arg2Of p53,with
R3366 T4765 T4764 arg2Of exposure,Upon
R3367 T4765 T4766 arg1Of exposure,to
R3368 T4765 T4771 arg1Of exposure,","
R3369 T4765 T4773 arg1Of exposure,as
R3370 T4767 T4768 arg1Of chemicals,or
R3371 T4768 T4766 arg2Of or,to
R3372 T4770 T4768 arg2Of stress,or
R3373 T4770 T4769 arg1Of stress,environmental
R3374 T4773 T4772 arg1Of as,such
R3375 T4775 T4774 arg1Of irradiation,UV
R3376 T4775 T4776 arg1Of irradiation,and
R3377 T4776 T4773 arg2Of and,as
R3378 T4778 T4776 arg2Of drugs,and
R3379 T4778 T4777 arg1Of drugs,chemotherapeutic
R3380 T4780 T4781 arg1Of WWOX,undergoes
R3381 T4781 T4764 arg1Of undergoes,Upon
R3382 T4781 T4779 arg1Of undergoes,","
R3383 T4781 T4783 arg1Of undergoes,in
R3384 T4781 T4789 arg1Of undergoes,","
R3385 T4781 T4790 modOf undergoes,followed
R3386 T4782 T4781 arg2Of phosphorylation,undergoes
R3387 T4784 T4785 arg1Of Tyr33,and
R3388 T4785 T4783 arg2Of and,in
R3389 T4788 T4785 arg2Of sites,and
R3390 T4788 T4786 arg1Of sites,probably
R3391 T4788 T4787 arg1Of sites,others
R3392 T4790 T4791 arg1Of followed,by
R3393 T4792 T4791 arg2Of relocating,by
R3394 T4792 T4793 arg1Of relocating,to
R3395 T4794 T4795 arg1Of mitochondria,or
R3396 T4795 T4793 arg2Of or,to
R3397 T4795 T4797 arg1Of or,for
R3398 T4796 T4795 arg2Of nuclei,or
R3399 T4798 T4797 arg2Of inducing,for
R34 T172 T169 arg2Of and,and
R3400 T4799 T4798 arg2Of apoptosis,inducing
R3401 T4799 T4800 arg1Of apoptosis,(
R3402 T4801 T4802 arg1Of Chang,et
R3403 T4801 T4803 arg1Of Chang,al.
R3404 T4801 T4804 arg1Of Chang,","
R3405 T4804 T4800 arg2Of ",",(
R3406 T4804 T4806 arg1Of ",",","
R3407 T4805 T4804 arg2Of 2007,","
R3408 T4807 T4806 arg2Of 2010,","
R3409 T4808 T4800 arg3Of ),(
R3410 T4809 T4810 arg1Of WWOX,binds
R3411 T4811 T4810 arg2Of MEK,binds
R3412 T4811 T4812 arg1Of MEK,in
R3413 T4815 T4812 arg2Of cells,in
R3414 T4815 T4813 arg1Of cells,Jurkat
R3415 T4815 T4814 arg1Of cells,T
R3416 T4815 T4816 arg1Of cells,(
R3417 T4817 T4816 arg2Of Lin,(
R3418 T4817 T4818 arg1Of Lin,et
R3419 T4817 T4819 arg1Of Lin,al.
R3420 T4817 T4820 arg1Of Lin,","
R3421 T4821 T4820 arg2Of 2011,","
R3422 T4822 T4816 arg3Of ),(
R3423 T4825 T4823 arg1Of acetate,Phorbol
R3424 T4825 T4824 arg1Of acetate,myristate
R3425 T4825 T4826 arg1Of acetate,(
R3426 T4825 T4829 arg1Of acetate,dissociates
R3427 T4825 T4834 arg1Of acetate,induces
R3428 T4827 T4826 arg2Of PMA,(
R3429 T4828 T4826 arg3Of ),(
R3430 T4829 T4833 arg1Of dissociates,and
R3431 T4832 T4829 arg2Of complex,dissociates
R3432 T4832 T4830 arg1Of complex,the
R3433 T4832 T4831 arg1Of complex,MEK/WWOX
R3434 T4834 T4833 arg2Of induces,and
R3435 T4835 T4834 arg2Of WWOX,induces
R3436 T4835 T4837 arg1Of WWOX,translocate
R3437 T4837 T4834 arg3Of translocate,induces
R3438 T4837 T4836 arg1Of translocate,to
R3439 T4837 T4838 arg1Of translocate,to
R3440 T4840 T4838 arg2Of mitochondria,to
R3441 T4840 T4839 arg1Of mitochondria,the
R3442 T4840 T4841 modOf mitochondria,to
R3443 T4842 T4841 arg1Of induce,to
R3444 T4842 T4844 arg1Of induce,","
R3445 T4842 T4845 arg1Of induce,whereas
R3446 T4843 T4842 arg2Of apoptosis,induce
R3447 T4846 T4847 arg1Of MEK,relocates
R3448 T4847 T4845 arg2Of relocates,whereas
R3449 T4847 T4848 arg1Of relocates,to
R3450 T4851 T4848 arg2Of raft,to
R3451 T4851 T4849 arg1Of raft,the
R3452 T4851 T4850 arg1Of raft,lipid
R3453 T4852 T4853 arg1Of Inhibition,of
R3454 T4852 T4856 arg1Of Inhibition,increases
R3455 T4855 T4853 arg2Of activity,of
R3456 T4855 T4854 arg1Of activity,MEK
R3457 T4856 T4863 arg1Of increases,(
R3458 T4858 T4856 arg2Of suppression,increases
R3459 T4858 T4857 arg1Of suppression,TMZ-induced
R3460 T4858 T4859 arg1Of suppression,of
R3461 T4862 T4859 arg2Of growth,of
R3462 T4862 T4860 arg1Of growth,cancer
R3463 T4862 T4861 arg1Of growth,cell
R3464 T4864 T4863 arg2Of Holt,(
R3465 T4864 T4865 arg1Of Holt,et
R3466 T4864 T4866 arg1Of Holt,al.
R3467 T4864 T4867 arg1Of Holt,","
R3468 T4868 T4867 arg2Of 2012,","
R3469 T4869 T4863 arg3Of ),(
R3470 T4871 T4870 arg1Of expression,Ectopic
R3471 T4871 T4872 arg1Of expression,of
R3472 T4871 T4874 arg1Of expression,in
R3473 T4871 T4877 arg1Of expression,induces
R3474 T4871 T4883 arg1Of expression,induces
R3475 T4873 T4872 arg2Of WWOX,of
R3476 T4876 T4874 arg2Of cells,in
R3477 T4876 T4875 arg1Of cells,A549
R3478 T4877 T4882 arg1Of induces,and
R3479 T4878 T4879 arg1Of procaspase-3,and
R3480 T4879 T4877 arg2Of and,induces
R3481 T4881 T4879 arg2Of activation,and
R3482 T4881 T4880 arg1Of activation,procaspase-9
R3483 T4882 T4896 arg1Of and,)
R3484 T4883 T4882 arg2Of induces,and
R3485 T4885 T4883 arg2Of C,induces
R3486 T4885 T4884 arg1Of C,cytochrome
R3487 T4885 T4886 arg1Of C,releasing
R3488 T4886 T4887 arg1Of releasing,from
R3489 T4889 T4887 arg2Of mitochondria,from
R3490 T4889 T4888 arg1Of mitochondria,the
R3491 T4891 T4886 arg2Of Zhang,releasing
R3492 T4891 T4890 arg1Of Zhang,(
R3493 T4891 T4892 arg1Of Zhang,et
R3494 T4891 T4893 arg1Of Zhang,al.
R3495 T4891 T4894 arg1Of Zhang,","
R3496 T4895 T4894 arg2Of 2012a,","
R3497 T4898 T4897 arg1Of C1q,Complement
R3498 T4898 T4899 arg1Of C1q,induces
R3499 T4898 T4906 arg1Of C1q,leads
R35 T174 T172 arg2Of Resistance,and
R3500 T4899 T4903 arg1Of induces,in
R3501 T4899 T4905 arg1Of induces,and
R3502 T4902 T4899 arg2Of phosphorylation,induces
R3503 T4902 T4900 arg1Of phosphorylation,ectopic
R3504 T4902 T4901 arg1Of phosphorylation,WWOX
R3505 T4904 T4903 arg2Of Try33,in
R3506 T4906 T4905 arg2Of leads,and
R3507 T4906 T4907 arg1Of leads,to
R3508 T4906 T4910 arg1Of leads,independently
R3509 T4906 T4917 arg1Of leads,(
R3510 T4909 T4907 arg2Of apoptosis,to
R3511 T4909 T4908 arg1Of apoptosis,cell
R3512 T4910 T4911 arg1Of independently,of
R3513 T4916 T4911 arg2Of pathway,of
R3514 T4916 T4912 arg1Of pathway,the
R3515 T4916 T4913 arg1Of pathway,classical
R3516 T4916 T4914 arg1Of pathway,complement
R3517 T4916 T4915 arg1Of pathway,activation
R3518 T4918 T4917 arg2Of Hong,(
R3519 T4918 T4919 arg1Of Hong,et
R3520 T4918 T4920 arg1Of Hong,al.
R3521 T4918 T4921 arg1Of Hong,","
R3522 T4922 T4921 arg2Of 2009,","
R3523 T4923 T4917 arg3Of ),(
R3524 T4925 T4924 arg1Of portion,A
R3525 T4925 T4926 arg1Of portion,of
R3526 T4925 T4928 arg1Of portion,is
R3527 T4925 T4929 arg2Of portion,anchored
R3528 T4927 T4926 arg2Of WWOX,of
R3529 T4929 T4928 arg2Of anchored,is
R3530 T4929 T4930 arg1Of anchored,in
R3531 T4929 T4934 arg1Of anchored,via
R3532 T4933 T4930 arg2Of area,in
R3533 T4933 T4931 arg1Of area,the
R3534 T4933 T4932 arg1Of area,membrane/cytoskeleton
R3535 T4935 T4934 arg2Of binding,via
R3536 T4935 T4936 arg1Of binding,with
R3537 T4938 T4937 arg1Of Hyal-2,hyaluronidase
R3538 T4938 T4939 arg1Of Hyal-2,(
R3539 T4938 T4946 arg1Of Hyal-2,and
R3540 T4940 T4939 arg2Of Hsu,(
R3541 T4940 T4941 arg1Of Hsu,et
R3542 T4940 T4942 arg1Of Hsu,al.
R3543 T4940 T4943 arg1Of Hsu,","
R3544 T4944 T4943 arg2Of 2009,","
R3545 T4945 T4939 arg3Of ),(
R3546 T4946 T4936 arg2Of and,with
R3547 T4947 T4946 arg2Of Phospho-Ezrin,and
R3548 T4947 T4948 arg1Of Phospho-Ezrin,(
R3549 T4949 T4948 arg2Of Jin,(
R3550 T4949 T4950 arg1Of Jin,et
R3551 T4949 T4951 arg1Of Jin,al.
R3552 T4949 T4952 arg1Of Jin,","
R3553 T4953 T4952 arg2Of 2006,","
R3554 T4954 T4948 arg3Of ),(
R3555 T4958 T4955 arg1Of β1,Transforming
R3556 T4958 T4956 arg1Of β1,growth
R3557 T4958 T4957 arg1Of β1,factor
R3558 T4958 T4959 arg1Of β1,binds
R3559 T4959 T4961 arg1Of binds,as
R3560 T4960 T4959 arg2Of Hyal-2,binds
R3561 T4964 T4961 arg2Of receptor,as
R3562 T4964 T4962 arg1Of receptor,a
R3563 T4964 T4963 arg1Of receptor,cognate
R3564 T4964 T4965 modOf receptor,to
R3565 T4966 T4965 arg1Of signal,to
R3566 T4968 T4966 arg2Of formation,signal
R3567 T4968 T4967 arg1Of formation,the
R3568 T4968 T4969 arg1Of formation,of
R3569 T4968 T4973 modOf formation,to
R3570 T4972 T4969 arg2Of complex,of
R3571 T4972 T4970 arg1Of complex,the
R3572 T4972 T4971 arg1Of complex,WWOX/Hyal-2/Smad4
R3573 T4974 T4973 arg1Of relocate,to
R3574 T4974 T4975 arg1Of relocate,to
R3575 T4977 T4975 arg2Of nucleus,to
R3576 T4977 T4976 arg1Of nucleus,the
R3577 T4977 T4978 arg1Of nucleus,for
R3578 T4979 T4978 arg2Of enhancing,for
R3579 T4979 T4984 arg1Of enhancing,(
R3580 T4983 T4979 arg2Of activity,enhancing
R3581 T4983 T4980 arg1Of activity,the
R3582 T4983 T4981 arg1Of activity,SMAD-driven
R3583 T4983 T4982 arg1Of activity,promoter
R3584 T4985 T4984 arg2Of Hsu,(
R3585 T4985 T4986 arg1Of Hsu,et
R3586 T4985 T4987 arg1Of Hsu,al.
R3587 T4985 T4988 arg1Of Hsu,","
R3588 T4989 T4988 arg2Of 2009,","
R3589 T4990 T4984 arg3Of ),(
R36 T174 T173 arg1Of Resistance,Drug
R37 T176 T175 arg2Of Glioblastomas,in
R38 T179 T177 arg1Of p53,Tumor
R39 T179 T178 arg1Of p53,suppressor
R40 T179 T180 arg1Of p53,are
R41 T179 T182 arg2Of p53,mutated
R42 T179 T189 arg1Of p53,appears
R43 T179 T191 arg1Of p53,contribute
R44 T182 T180 arg2Of mutated,are
R45 T182 T181 arg1Of mutated,frequently
R46 T182 T183 arg1Of mutated,in
R464 T915 T910 arg1Of patients,Glioblastoma
R465 T915 T911 arg1Of patients,multiforme
R466 T915 T912 arg1Of patients,afflicts
R467 T915 T913 arg1Of patients,"12,500"
R468 T915 T914 arg1Of patients,new
R469 T915 T916 arg1Of patients,in
R47 T182 T188 arg1Of mutated,and
R470 T915 T919 arg1Of patients,annually
R471 T915 T920 arg1Of patients,(
R472 T918 T916 arg2Of U.S.,in
R473 T918 T917 arg1Of U.S.,the
R474 T921 T920 arg2Of Friedman,(
R475 T921 T922 arg1Of Friedman,et
R476 T921 T923 arg1Of Friedman,al.
R477 T921 T924 arg1Of Friedman,","
R478 T921 T926 arg1Of Friedman,;
R479 T921 T932 arg1Of Friedman,;
R48 T184 T183 arg2Of glioblastomas,in
R480 T925 T924 arg2Of 2000,","
R4805 T6868 T6867 arg2Of p53,Activated
R4806 T6868 T6869 arg1Of p53,mediates
R4807 T6870 T6871 arg1Of apoptosis,","
R4808 T6871 T6875 arg1Of ",",","
R4809 T6874 T6871 arg2Of arrest,","
R481 T927 T926 arg2Of Stupp,;
R4810 T6874 T6872 arg1Of arrest,cell
R4811 T6874 T6873 arg1Of arrest,cycle
R4812 T6875 T6877 arg1Of ",",","
R4813 T6876 T6875 arg2Of senescence,","
R4814 T6877 T6881 arg1Of ",",or
R4815 T6879 T6877 arg2Of repair,","
R4816 T6879 T6878 arg1Of repair,DNA
R4817 T6881 T6869 arg2Of or,mediates
R4818 T6881 T6880 arg1Of or,","
R4819 T6882 T6881 arg2Of metabolism,or
R482 T927 T928 arg1Of Stupp,et
R4820 T6882 T6883 arg1Of metabolism,(
R4821 T6884 T6885 arg1Of Lane,and
R4822 T6885 T6883 arg2Of and,(
R4823 T6885 T6887 arg1Of and,","
R4824 T6886 T6885 arg2Of Levine,and
R4825 T6888 T6887 arg2Of 2010,","
R4826 T6889 T6883 arg3Of ),(
R4827 T6892 T6890 arg1Of structures,The
R4828 T6892 T6891 arg1Of structures,primary
R4829 T6892 T6893 arg1Of structures,of
R483 T927 T929 arg1Of Stupp,al.
R4830 T6894 T6893 arg2Of p53,of
R4831 T6897 T6896 arg1Of isoforms,its
R4832 T6897 T6898 arg1Of isoforms,are
R4833 T6897 T6899 arg2Of isoforms,depicted
R4834 T6899 T6898 arg2Of depicted,are
R4835 T6901 T6900 arg2Of Figure,(
R4836 T6901 T6902 arg1Of Figure,2
R4837 T6903 T6900 arg3Of ),(
R4838 T6904 T6899 arg3Of . p,depicted
R4839 T6904 T6900 arg1Of . p,(
R484 T927 T930 arg1Of Stupp,","
R4840 T6905 T6909 arg1Of 53 indu,ar
R4841 T6908 T6905 arg2Of cycle ,53 indu
R4842 T6908 T6906 arg1Of cycle ,ces
R4843 T6908 T6907 arg1Of cycle ,cell
R4844 T6910 T6909 arg2Of rest by transac,ar
R4845 T6911 T6910 arg2Of tivat,rest by transac
R4846 T6911 T6913 arg1Of tivat,ge
R4847 T6913 T6912 arg1Of ge,ing
R4848 T6917 T6913 arg2Of nas,ge
R4849 T6917 T6914 arg1Of nas,nes such as cycl
R485 T931 T930 arg2Of 2009,","
R4850 T6917 T6915 arg1Of nas,in-dep
R4851 T6917 T6916 arg1Of nas,endent ki
R4852 T6919 T6918 arg1Of in,e
R4853 T6922 T6920 arg1Of r m,hibitor
R4854 T6922 T6921 arg1Of r m,"p21, o"
R4855 T6922 T6923 arg1Of r m,icroRNA
R4856 T6922 T6926 arg1Of r m,induces apoptos
R4857 T6922 T6941 arg1Of r m,", PUMA, SC"
R4858 T6923 T6925 arg1Of icroRNA,3
R4859 T6924 T6923 arg2Of miR34. p5,icroRNA
R486 T933 T932 arg2Of Silber,;
R4860 T6926 T6940 arg1Of induces apoptos,BAX
R4861 T6928 T6926 arg2Of ctiva,induces apoptos
R4862 T6928 T6927 arg1Of ctiva,is by transa
R4863 T6928 T6930 arg1Of ctiva,pr
R4864 T6930 T6929 arg1Of pr,ting
R4865 T6931 T6932 arg1Of oap,o
R4866 T6932 T6934 arg1Of o,i
R4867 T6933 T6932 arg2Of ptot,o
R4868 T6934 T6937 arg1Of i,suc
R4869 T6935 T6934 arg2Of c gene,i
R487 T933 T934 arg1Of Silber,et
R4870 T6937 T6930 arg2Of suc,pr
R4871 T6937 T6936 arg1Of suc,s
R4872 T6938 T6937 arg2Of h a,suc
R4873 T6940 T6925 arg2Of BAX,3
R4874 T6940 T6939 arg1Of BAX,s
R4875 T6941 T6940 arg2Of ", PUMA, SC",BAX
R4876 T6945 T6941 arg2Of nhibi,", PUMA, SC"
R4877 T6945 T6942 arg1Of nhibi,OTI
R4878 T6945 T6943 arg1Of nhibi,"N, and FAS, a"
R4879 T6945 T6944 arg1Of nhibi,nd i
R488 T933 T935 arg1Of Silber,al.
R4880 T6947 T6948 arg1Of ing ,the
R4881 T6948 T6946 arg2Of the,t
R4882 T6948 T6950 arg1Of the,o
R4883 T6949 T6948 arg2Of antiap,the
R4884 T6951 T6950 arg2Of ptot,o
R4885 T6952 T6946 arg3Of i,t
R4886 T6953 T6954 arg1Of c g,ene BCL-
R4887 T6954 T6960 arg1Of ene BCL-,t
R4888 T6954 T6961 arg1Of ene BCL-,riggers p
R4889 T6959 T6954 arg2Of 0). p53 ,ene BCL-
R489 T933 T936 arg1Of Silber,","
R4890 T6959 T6955 arg1Of 0). p53 ,2 (Lane and
R4891 T6959 T6956 arg1Of 0). p53 ,Le
R4892 T6959 T6957 arg1Of 0). p53 ,vine
R4893 T6959 T6958 arg1Of 0). p53 ,", 201"
R4894 T6962 T6961 arg2Of ro-s,riggers p
R4895 T6964 T6962 arg2Of val o,ro-s
R4896 T6964 T6963 arg1Of val o,urvi
R4897 T6967 T6966 arg1Of l death r,cel
R4898 T6967 T6968 arg1Of l death r,es
R4899 T6971 T6968 arg2Of pendin,es
R49 T184 T185 arg1Of glioblastomas,(
R490 T937 T936 arg2Of 2012,","
R4900 T6971 T6969 arg1Of pendin,pon
R4901 T6971 T6970 arg1Of pendin,"se, de"
R4902 T6973 T6972 arg1Of upo,g
R4903 T6975 T6974 arg1Of ell ty,n c
R4904 T6975 T6976 arg1Of ell ty,pe
R4905 T6978 T6976 arg2Of ntensi,pe
R4906 T6978 T6977 arg1Of ntensi,"s, the i"
R4907 T6980 T6979 arg2Of y of the,t
R4908 T6980 T6981 arg1Of y of the,st
R4909 T6980 T6982 arg1Of y of the,res
R491 T938 T920 arg3Of ),(
R4910 T6980 T6983 arg1Of y of the,s
R4911 T6984 T6983 arg2Of sign,s
R4912 T6985 T6979 arg3Of a,t
R4913 T6988 T6989 arg1Of p53,plays
R4914 T6988 T6993 arg1Of p53,controlling
R4915 T6989 T6986 arg1Of plays,Also
R4916 T6989 T6987 arg1Of plays,","
R4917 T6989 T6992 arg1Of plays,in
R4918 T6991 T6989 arg2Of role,plays
R4919 T6991 T6990 arg1Of role,a
R492 T939 T940 arg1Of Glioblastoma,(
R4920 T6993 T6992 arg2Of controlling,in
R4921 T6993 T6996 arg1Of controlling,via
R4922 T6995 T6993 arg2Of motility,controlling
R4923 T6995 T6994 arg1Of motility,cell
R4924 T6997 T7016 arg1Of regulating,(
R4925 T6997 T7024 arg1Of regulating,and
R4926 T6999 T6997 arg2Of expression,regulating
R4927 T6999 T6998 arg1Of expression,the
R4928 T6999 T7000 arg1Of expression,of
R4929 T7003 T7001 arg1Of α-actin,smooth
R493 T939 T943 arg1Of Glioblastoma,is
R4930 T7003 T7002 arg1Of α-actin,muscle
R4931 T7003 T7004 arg1Of α-actin,(
R4932 T7003 T7011 arg1Of α-actin,","
R4933 T7005 T7004 arg2Of Comer,(
R4934 T7005 T7006 arg1Of Comer,et
R4935 T7005 T7007 arg1Of Comer,al.
R4936 T7005 T7008 arg1Of Comer,","
R4937 T7009 T7008 arg2Of 1998,","
R4938 T7010 T7004 arg3Of ),(
R4939 T7011 T7000 arg2Of ",",of
R494 T939 T945 arg1Of Glioblastoma,lethal
R4940 T7013 T7014 arg1Of IIα1,and
R4941 T7014 T7011 arg2Of and,","
R4942 T7014 T7012 arg1Of and,collagens
R4943 T7015 T7014 arg2Of VIα1,and
R4944 T7017 T7016 arg2Of Sun,(
R4945 T7017 T7018 arg1Of Sun,et
R4946 T7017 T7019 arg1Of Sun,al.
R4947 T7017 T7020 arg1Of Sun,","
R4948 T7021 T7020 arg2Of 1999,","
R4949 T7022 T7016 arg3Of ),(
R495 T941 T940 arg2Of GBM,(
R4950 T7024 T6996 arg2Of and,via
R4951 T7024 T7023 arg1Of and,","
R4952 T7026 T7024 arg2Of others,and
R4953 T7026 T7025 arg1Of others,many
R496 T942 T940 arg3Of ),(
R497 T943 T947 arg1Of is,and
R498 T945 T943 arg2Of lethal,is
R499 T945 T944 arg1Of lethal,highly
R50 T186 T185 arg2Of GBMs,(
R500 T947 T946 arg1Of and,","
R501 T947 T955 arg1Of and,and
R502 T951 T948 arg1Of expectancy,the
R503 T951 T949 arg1Of expectancy,average
R504 T951 T950 arg1Of expectancy,survival
R505 T951 T952 arg1Of expectancy,is
R506 T951 T953 arg1Of expectancy,14.6 months
R507 T952 T947 arg2Of is,and
R508 T953 T952 arg2Of 14.6 months,is
R509 T955 T954 arg1Of and,","
R51 T187 T185 arg3Of ),(
R510 T960 T956 arg1Of rate,the
R511 T960 T957 arg1Of rate,overall
R512 T960 T958 arg1Of rate,5-year
R513 T960 T959 arg1Of rate,survival
R514 T960 T961 arg1Of rate,for
R515 T960 T963 arg1Of rate,is
R516 T962 T961 arg2Of GBM,for
R517 T963 T955 arg2Of is,and
R518 T963 T967 arg1Of is,(
R519 T965 T964 arg1Of 9.8,only
R52 T189 T188 arg2Of appears,and
R520 T966 T963 arg2Of %,is
R521 T966 T965 arg1Of %,9.8
R522 T968 T967 arg2Of Friedman,(
R523 T968 T969 arg1Of Friedman,et
R524 T968 T970 arg1Of Friedman,al.
R525 T968 T971 arg1Of Friedman,","
R5250 T7622 T7620 arg1Of nine,At
R5251 T7622 T7621 arg1Of nine,least
R5252 T7623 T7622 arg1Of isoforms,nine
R5253 T7623 T7624 arg1Of isoforms,of
R5254 T7623 T7626 arg1Of isoforms,have
R5255 T7623 T7627 arg1Of isoforms,been
R5256 T7623 T7628 arg2Of isoforms,identified
R5257 T7625 T7624 arg2Of p53,of
R5258 T7628 T7626 arg2Of identified,have
R5259 T7628 T7627 arg2Of identified,been
R526 T968 T973 arg1Of Friedman,;
R5260 T7628 T7630 arg1Of identified,to
R5261 T7628 T7645 arg1Of identified,(
R5262 T7630 T7629 arg1Of to,due
R5263 T7633 T7631 arg1Of splicing,alternative
R5264 T7633 T7632 arg1Of splicing,mRNA
R5265 T7633 T7634 arg1Of splicing,","
R5266 T7634 T7639 arg1Of ",",and
R5267 T7637 T7634 arg2Of promoters,","
R5268 T7637 T7635 arg1Of promoters,multiple
R5269 T7637 T7636 arg1Of promoters,gene
R527 T972 T971 arg2Of 2000,","
R5270 T7639 T7630 arg2Of and,to
R5271 T7639 T7638 arg1Of and,","
R5272 T7642 T7639 arg2Of sites,and
R5273 T7642 T7640 arg1Of sites,alternative
R5274 T7642 T7641 arg1Of sites,initiation
R5275 T7642 T7643 arg1Of sites,of
R5276 T7644 T7643 arg2Of translation,of
R5277 T7646 T7645 arg2Of Ghosh,(
R5278 T7646 T7647 arg1Of Ghosh,et
R5279 T7646 T7648 arg1Of Ghosh,al.
R528 T974 T973 arg2Of Stupp,;
R5280 T7646 T7649 arg1Of Ghosh,","
R5281 T7646 T7651 arg1Of Ghosh,;
R5282 T7646 T7657 arg1Of Ghosh,;
R5283 T7650 T7649 arg2Of 2004,","
R5284 T7652 T7653 arg1Of Ray,et
R5285 T7652 T7654 arg1Of Ray,al.
R5286 T7652 T7655 arg1Of Ray,","
R5287 T7655 T7651 arg2Of ",",;
R5288 T7656 T7655 arg2Of 2006,","
R5289 T7658 T7657 arg2Of Figure,;
R529 T974 T975 arg1Of Stupp,et
R5290 T7658 T7659 arg1Of Figure,2
R5291 T7660 T7645 arg3Of ),(
R5292 T7662 T7661 arg2Of cancers,In
R5293 T7665 T7664 arg1Of expression,aberrant
R5294 T7665 T7666 arg1Of expression,of
R5295 T7665 T7669 arg1Of expression,occurs
R5296 T7668 T7666 arg2Of isoforms,of
R5297 T7668 T7667 arg1Of isoforms,p53
R5298 T7669 T7661 arg1Of occurs,In
R5299 T7669 T7663 arg1Of occurs,","
R53 T191 T189 arg2Of contribute,appears
R530 T974 T976 arg1Of Stupp,al.
R5300 T7669 T7670 arg1Of occurs,frequently
R5301 T7669 T7671 arg1Of occurs,(
R5302 T7672 T7671 arg2Of Bourdon,(
R5303 T7672 T7673 arg1Of Bourdon,et
R5304 T7672 T7674 arg1Of Bourdon,al.
R5305 T7672 T7675 arg1Of Bourdon,","
R5306 T7672 T7677 arg1Of Bourdon,;
R5307 T7676 T7675 arg2Of 2005,","
R5308 T7678 T7677 arg2Of Bourdon,;
R5309 T7678 T7679 arg1Of Bourdon,","
R531 T974 T977 arg1Of Stupp,","
R5310 T7680 T7679 arg2Of 2007,","
R5311 T7681 T7671 arg3Of ),(
R5312 T7683 T7682 arg1Of p53,Full-length
R5313 T7683 T7684 arg1Of p53,","
R5314 T7684 T7687 arg1Of ",",and
R5315 T7685 T7684 arg2Of Δ133p53,","
R5316 T7687 T7686 arg1Of and,","
R5317 T7687 T7689 arg1Of and,are
R5318 T7687 T7690 arg2Of and,localized
R5319 T7688 T7687 arg2Of p53β,and
R532 T978 T977 arg2Of 2009,","
R5320 T7690 T7689 arg2Of localized,are
R5321 T7690 T7692 arg1Of localized,in
R5322 T7690 T7696 arg1Of localized,and
R5323 T7692 T7691 arg1Of in,mainly
R5324 T7694 T7692 arg2Of nucleus,in
R5325 T7694 T7693 arg1Of nucleus,the
R5326 T7696 T7695 arg1Of and,","
R5327 T7696 T7720 arg1Of and,(
R5328 T7698 T7697 arg1Of few,only
R5329 T7698 T7699 arg1Of few,of
R533 T979 T967 arg3Of ),(
R5330 T7698 T7701 arg1Of few,are
R5331 T7698 T7702 arg1Of few,in
R5332 T7700 T7699 arg2Of them,of
R5333 T7701 T7705 arg1Of are,and
R5334 T7702 T7701 arg2Of in,are
R5335 T7704 T7702 arg2Of p53γ,in
R5336 T7704 T7703 arg1Of p53γ,cytoplasm.
R5337 T7705 T7696 arg2Of and,and
R5338 T7706 T7707 arg1Of Δ133p53β,are
R5339 T7706 T7708 arg2Of Δ133p53β,localized
R534 T981 T980 arg1Of levels,High
R5340 T7708 T7707 arg2Of localized,are
R5341 T7708 T7709 arg1Of localized,in
R5342 T7708 T7712 arg1Of localized,and
R5343 T7711 T7709 arg2Of nucleus,in
R5344 T7711 T7710 arg1Of nucleus,the
R5345 T7712 T7705 arg2Of and,and
R5346 T7714 T7713 arg1Of Δ133p53γ,cytoplasm.
R5347 T7714 T7715 arg1Of Δ133p53γ,is
R5348 T7714 T7716 arg1Of Δ133p53γ,localized
R5349 T7715 T7712 arg2Of is,and
R535 T981 T982 arg1Of levels,of
R5350 T7716 T7715 arg2Of localized,is
R5351 T7716 T7717 arg1Of localized,in
R5352 T7719 T7717 arg2Of cytoplasm,in
R5353 T7719 T7718 arg1Of cytoplasm,the
R5354 T7721 T7720 arg2Of Bourdon,(
R5355 T7721 T7722 arg1Of Bourdon,et
R5356 T7721 T7723 arg1Of Bourdon,al.
R5357 T7721 T7724 arg1Of Bourdon,","
R5358 T7725 T7724 arg2Of 2005,","
R5359 T7726 T7720 arg3Of ),(
R536 T981 T991 arg1Of levels,are
R5360 T7727 T7728 arg1Of Co-transfection,of
R5361 T7727 T7732 arg1Of Co-transfection,increases
R5362 T7729 T7730 arg1Of p53,and
R5363 T7730 T7728 arg2Of and,of
R5364 T7731 T7730 arg2Of p53β,and
R5365 T7732 T7736 arg1Of increases,whereas
R5366 T7734 T7732 arg2Of apoptosis,increases
R5367 T7734 T7733 arg1Of apoptosis,p53-mediated
R5368 T7736 T7735 arg1Of whereas,","
R5369 T7737 T7738 arg1Of co-expression,of
R537 T981 T993 arg2Of levels,seen
R5370 T7737 T7740 arg1Of co-expression,with
R5371 T7737 T7742 arg1Of co-expression,suppresses
R5372 T7739 T7738 arg2Of p53,of
R5373 T7741 T7740 arg2Of Δ133p53,with
R5374 T7742 T7736 arg2Of suppresses,whereas
R5375 T7742 T7745 arg1Of suppresses,(
R5376 T7744 T7742 arg2Of apoptosis,suppresses
R5377 T7744 T7743 arg1Of apoptosis,p53-mediated
R5378 T7746 T7745 arg2Of Bourdon,(
R5379 T7746 T7747 arg1Of Bourdon,et
R538 T983 T984 arg1Of resistance,to
R5380 T7746 T7748 arg1Of Bourdon,al.
R5381 T7746 T7749 arg1Of Bourdon,","
R5382 T7750 T7749 arg2Of 2005,","
R5383 T7751 T7745 arg3Of ),(
R5384 T7752 T7754 arg1Of . Δ133p,lly regul
R5385 T7754 T7742 arg3Of lly regul,suppresses
R5386 T7754 T7753 arg1Of lly regul,53 differentia
R5387 T7756 T7754 arg2Of gene expre,lly regul
R5388 T7756 T7755 arg1Of gene expre,ates
R5389 T7756 T7757 arg1Of gene expre,ss
R539 T983 T988 arg1Of resistance,and
R5390 T7758 T7759 arg1Of ion in p53-de,pen
R5391 T7760 T7759 arg2Of dent and -in,pen
R5392 T7761 T7757 arg2Of depende,ss
R5393 T7761 T7758 arg1Of depende,ion in p53-de
R5394 T7761 T7760 arg1Of depende,dent and -in
R5395 T7761 T7762 arg1Of depende,n
R5396 T7763 T7762 arg2Of t manne,n
R5397 T7763 T7764 arg1Of t manne,rs
R5398 T7763 T7765 arg1Of t manne,(Ao
R5399 T7763 T7766 arg1Of t manne,u
R54 T191 T190 arg1Of contribute,to
R540 T987 T984 arg2Of modalities,to
R5400 T7767 T7766 arg2Of bala,u
R5401 T7768 T7762 arg3Of e,n
R5402 T7769 T7770 arg1Of Co-expression,of
R5403 T7769 T7774 arg1Of Co-expression,with
R5404 T7769 T7776 arg1Of Co-expression,does
R5405 T7769 T7778 arg1Of Co-expression,affect
R5406 T7771 T7772 arg1Of Δ133p53β,or
R5407 T7772 T7770 arg2Of or,of
R5408 T7773 T7772 arg2Of Δ133p53γ,or
R5409 T7775 T7774 arg2Of p53,with
R541 T987 T985 arg1Of modalities,current
R5410 T7778 T7776 arg2Of affect,does
R5411 T7778 T7777 arg1Of affect,not
R5412 T7781 T7779 arg1Of activity,p53
R5413 T7781 T7780 arg1Of activity,transcriptional
R5414 T7781 T7782 arg1Of activity,on
R5415 T7781 T7790 arg1Of activity,as
R5416 T7783 T7784 arg1Of p21,and
R5417 T7785 T7784 arg2Of Bax,and
R5418 T7786 T7782 arg2Of promoters,on
R5419 T7786 T7783 arg1Of promoters,p21
R542 T987 T986 arg1Of modalities,therapeutic
R5420 T7786 T7785 arg1Of promoters,Bax
R5421 T7790 T7778 arg2Of as,affect
R5422 T7790 T7787 arg1Of as,","
R5423 T7790 T7788 arg1Of as,as
R5424 T7790 T7789 arg1Of as,well
R5425 T7791 T7790 arg2Of apoptosis,as
R543 T988 T982 arg2Of and,of
R544 T990 T988 arg2Of relapse,and
R545 T990 T989 arg1Of relapse,cancer
R546 T993 T991 arg2Of seen,are
R547 T993 T992 arg1Of seen,frequently
R548 T993 T994 arg1Of seen,in
R549 T993 T996 arg1Of seen,(
R55 T191 T192 arg1Of contribute,","
R550 T995 T994 arg2Of patients,in
R551 T997 T996 arg2Of Haar,(
R552 T997 T998 arg1Of Haar,et
R553 T997 T999 arg1Of Haar,al.
R554 T997 T1000 arg1Of Haar,","
R555 T997 T1002 arg1Of Haar,;
R556 T1001 T1000 arg2Of 2012,","
R557 T1003 T1002 arg2Of Happold,;
R558 T1003 T1004 arg1Of Happold,et
R559 T1003 T1005 arg1Of Happold,al.
R56 T191 T193 arg1Of contribute,in
R560 T1003 T1006 arg1Of Happold,","
R561 T1007 T1006 arg2Of 2012,","
R562 T1008 T996 arg3Of ),(
R563 T1012 T1010 arg1Of therapy,current
R564 T1012 T1011 arg1Of therapy,standard
R565 T1012 T1013 arg1Of therapy,for
R566 T1012 T1016 arg1Of therapy,includes
R567 T1012 T1009 arg1Of therapy,The
R568 T1014 T1013 arg2Of GBM,for
R569 T1016 T1015 arg1Of includes,mainly
R57 T191 T195 arg1Of contribute,","
R570 T1019 T1017 arg1Of surgery,maximum
R571 T1019 T1018 arg1Of surgery,debulking
R572 T1019 T1020 arg1Of surgery,","
R573 T1020 T1023 arg1Of ",",and
R574 T1021 T1020 arg2Of radiation,","
R575 T1023 T1016 arg2Of and,includes
R576 T1023 T1022 arg1Of and,","
R577 T1024 T1023 arg2Of treatment,and
R578 T1024 T1025 arg1Of treatment,with
R579 T1030 T1025 arg2Of temozolomide,with
R58 T191 T196 arg1Of contribute,to
R580 T1030 T1026 arg1Of temozolomide,the
R581 T1030 T1027 arg1Of temozolomide,monofunctional
R5812 T8541 T8540 arg1Of mutants,p53
R5813 T8541 T8542 arg1Of mutants,are
R5814 T8541 T8543 arg2Of mutants,considered
R5815 T8543 T8542 arg2Of considered,are
R5816 T8543 T8544 arg1Of considered,as
R5817 T8543 T8555 arg1Of considered,in
R5818 T8546 T8544 arg2Of factors,as
R5819 T8546 T8545 arg1Of factors,unfavorable
R582 T1030 T1028 arg1Of temozolomide,alkylating
R5820 T8546 T8547 arg1Of factors,for
R5821 T8549 T8547 arg2Of effectiveness,for
R5822 T8549 T8548 arg1Of effectiveness,the
R5823 T8549 T8550 arg1Of effectiveness,in
R5824 T8551 T8552 arg1Of radiotherapy,and
R5825 T8553 T8552 arg2Of TMZ,and
R5826 T8554 T8550 arg2Of treatment,in
R5827 T8554 T8551 arg1Of treatment,radiotherapy
R5828 T8554 T8553 arg1Of treatment,TMZ
R5829 T8557 T8555 arg2Of cells,in
R583 T1030 T1029 arg1Of temozolomide,agent
R5830 T8557 T8556 arg1Of cells,glioma
R5831 T8557 T8558 arg1Of cells,(
R5832 T8559 T8560 arg1Of Gjerset,et
R5833 T8559 T8561 arg1Of Gjerset,al.
R5834 T8559 T8562 arg1Of Gjerset,","
R5835 T8562 T8558 arg2Of ",",(
R5836 T8562 T8564 arg1Of ",",;
R5837 T8562 T8570 arg1Of ",",;
R5838 T8563 T8562 arg2Of 1995,","
R5839 T8565 T8564 arg2Of Hirose,;
R584 T1030 T1031 arg1Of temozolomide,(
R5840 T8565 T8566 arg1Of Hirose,et
R5841 T8565 T8567 arg1Of Hirose,al.
R5842 T8565 T8568 arg1Of Hirose,","
R5843 T8569 T8568 arg2Of 2001,","
R5844 T8571 T8570 arg2Of Squatrito,;
R5845 T8571 T8572 arg1Of Squatrito,et
R5846 T8571 T8573 arg1Of Squatrito,al.
R5847 T8571 T8574 arg1Of Squatrito,","
R5848 T8571 T8576 arg1Of Squatrito,;
R5849 T8575 T8574 arg2Of 2010,","
R585 T1030 T1034 arg1Of temozolomide,(
R5850 T8577 T8576 arg2Of Blough,;
R5851 T8577 T8578 arg1Of Blough,et
R5852 T8577 T8579 arg1Of Blough,al.
R5853 T8577 T8580 arg1Of Blough,","
R5854 T8581 T8580 arg2Of 2011,","
R5855 T8582 T8558 arg3Of ),(
R5856 T8583 T8584 arg1Of Loss,of
R5857 T8583 T8587 arg1Of Loss,confers
R5858 T8586 T8584 arg2Of p53,of
R5859 T8586 T8585 arg1Of p53,functional
R586 T1032 T1031 arg2Of TMZ,(
R5860 T8587 T8589 arg1Of confers,to
R5861 T8587 T8591 arg1Of confers,in
R5862 T8587 T8595 arg1Of confers,whereas
R5863 T8588 T8587 arg2Of sensitivity,confers
R5864 T8590 T8589 arg2Of TMZ,to
R5865 T8593 T8591 arg2Of cells,in
R5866 T8593 T8592 arg1Of cells,glioma
R5867 T8595 T8594 arg1Of whereas,","
R5868 T8598 T8596 arg1Of p53,wild
R5869 T8598 T8597 arg1Of p53,type
R587 T1033 T1031 arg3Of ),(
R5870 T8598 T8599 arg1Of p53,increases
R5871 T8599 T8595 arg2Of increases,whereas
R5872 T8602 T8599 arg2Of resistance,increases
R5873 T8602 T8600 arg1Of resistance,the
R5874 T8602 T8601 arg1Of resistance,TMZ
R5875 T8602 T8603 arg1Of resistance,(
R5876 T8602 T8612 arg2Of resistance,nts re
R5877 T8602 T8615 arg1Of resistance,ti
R5878 T8604 T8603 arg2Of Blough,(
R5879 T8604 T8605 arg1Of Blough,et
R588 T1035 T1034 arg2Of Friedman,(
R5880 T8604 T8606 arg1Of Blough,al.
R5881 T8604 T8607 arg1Of Blough,","
R5882 T8608 T8607 arg2Of 2011,","
R5883 T8609 T8603 arg3Of ),(
R5884 T8611 T8610 arg1Of 53 muta,. p
R5885 T8611 T8612 arg1Of 53 muta,nts re
R5886 T8614 T8612 arg3Of e TMZ sensi,nts re
R5887 T8614 T8613 arg1Of e TMZ sensi,duc
R5888 T8616 T8615 arg2Of vity in,ti
R5889 T8616 T8617 arg1Of vity in,g
R589 T1035 T1036 arg1Of Friedman,et
R5890 T8618 T8617 arg2Of liomas,g
R5891 T8618 T8619 arg1Of liomas,(B
R5892 T8618 T8620 arg1Of liomas,lou
R5893 T8618 T8621 arg1Of liomas,g
R5894 T8622 T8621 arg2Of h et,g
R5895 T8623 T8617 arg3Of a,g
R5896 T8626 T8624 arg2Of expression,Altered
R5897 T8626 T8625 arg1Of expression,WWOX
R5898 T8626 T8627 arg1Of expression,is
R5899 T8626 T8628 arg2Of expression,shown
R59 T194 T193 arg2Of part,in
R590 T1035 T1037 arg1Of Friedman,al.
R5900 T8628 T8627 arg2Of shown,is
R5901 T8628 T8629 arg1Of shown,in
R5902 T8630 T8629 arg2Of GBMs,in
R5903 T8630 T8632 arg2Of GBMs,in
R5904 T8630 T8633 arg1Of GBMs,which
R5905 T8634 T8635 arg1Of downregulation,of
R5906 T8634 T8637 arg1Of downregulation,is
R5907 T8634 T8638 arg2Of downregulation,associated
R5908 T8636 T8635 arg2Of WWOX,of
R5909 T8638 T8631 arg1Of associated,","
R591 T1035 T1038 arg1Of Friedman,","
R5910 T8638 T8632 arg1Of associated,in
R5911 T8638 T8637 arg2Of associated,is
R5912 T8638 T8639 arg1Of associated,with
R5913 T8640 T8639 arg2Of loss,with
R5914 T8640 T8641 arg1Of loss,of
R5915 T8642 T8643 arg1Of heterozygosity,and
R5916 T8644 T8643 arg2Of promoter,and
R5917 T8645 T8641 arg2Of methylation,of
R5918 T8645 T8642 arg1Of methylation,heterozygosity
R5919 T8645 T8644 arg1Of methylation,promoter
R592 T1035 T1040 arg1Of Friedman,;
R5920 T8645 T8646 arg1Of methylation,(
R5921 T8647 T8646 arg2Of Kosla,(
R5922 T8647 T8648 arg1Of Kosla,et
R5923 T8647 T8649 arg1Of Kosla,al.
R5924 T8647 T8650 arg1Of Kosla,","
R5925 T8651 T8650 arg2Of 2011,","
R5926 T8652 T8646 arg3Of ),(
R5927 T8655 T8656 arg1Of we,demonstrated
R5928 T8656 T8653 arg1Of demonstrated,Recently
R5929 T8656 T8654 arg1Of demonstrated,","
R593 T1039 T1038 arg2Of 2000,","
R5930 T8659 T8658 arg2Of WWOX,overexpressed
R5931 T8659 T8660 arg1Of WWOX,induces
R5932 T8659 T8670 arg1Of WWOX,causing
R5933 T8660 T8656 arg2Of induces,demonstrated
R5934 T8660 T8657 arg1Of induces,that
R5935 T8660 T8669 arg1Of induces,by
R5936 T8661 T8660 arg2Of apoptosis,induces
R5937 T8661 T8662 arg1Of apoptosis,of
R5938 T8665 T8662 arg2Of cells,of
R5939 T8665 T8663 arg1Of cells,glioblastoma
R594 T1041 T1040 arg2Of Nishikawa,;
R5940 T8665 T8664 arg1Of cells,U373-MG
R5941 T8665 T8666 arg1Of cells,harboring
R5942 T8668 T8666 arg2Of p53,harboring
R5943 T8668 T8667 arg1Of p53,mutant
R5944 T8670 T8669 arg2Of causing,by
R5945 T8670 T8675 arg1Of causing,(
R5946 T8671 T8672 arg1Of hypoploidy,and
R5947 T8672 T8670 arg2Of and,causing
R5948 T8674 T8672 arg2Of fragmentation,and
R5949 T8674 T8673 arg1Of fragmentation,DNA
R595 T1041 T1042 arg1Of Nishikawa,","
R5950 T8676 T8675 arg2Of Chiang,(
R5951 T8676 T8677 arg1Of Chiang,et
R5952 T8676 T8678 arg1Of Chiang,al.
R5953 T8676 T8679 arg1Of Chiang,","
R5954 T8680 T8679 arg2Of 2012,","
R5955 T8681 T8675 arg3Of ),(
R5956 T8685 T8684 arg1Of WWOX,ectopic
R5957 T8685 T8686 arg1Of WWOX,has
R5958 T8686 T8682 arg1Of has,However
R5959 T8686 T8683 arg1Of has,","
R596 T1043 T1042 arg2Of 2010,","
R5960 T8688 T8686 arg2Of effect,has
R5961 T8688 T8687 arg1Of effect,no
R5962 T8688 T8689 arg1Of effect,with
R5963 T8690 T8689 arg2Of U87-MG,with
R5964 T8690 T8691 arg1Of U87-MG,expressing
R5965 T8694 T8691 arg2Of p53,expressing
R5966 T8694 T8692 arg1Of p53,wild
R5967 T8694 T8693 arg1Of p53,type
R5968 T8696 T8695 arg2Of TMZ,Unlike
R5969 T8698 T8699 arg1Of WWOX,induces
R597 T1044 T1034 arg3Of ),(
R5970 T8699 T8695 arg1Of induces,Unlike
R5971 T8699 T8697 arg1Of induces,","
R5972 T8699 T8704 arg1Of induces,via
R5973 T8700 T8699 arg2Of apoptosis,induces
R5974 T8700 T8701 arg1Of apoptosis,of
R5975 T8703 T8701 arg2Of cells,of
R5976 T8703 T8702 arg1Of cells,U373-MG
R5977 T8706 T8707 arg1Of mitochondria-independent,and
R5978 T8708 T8707 arg2Of caspase-3-independent,and
R5979 T8709 T8704 arg2Of pathway,via
R598 T1046 T1045 arg1Of mechanisms,Multiple
R5980 T8709 T8705 arg1Of pathway,a
R5981 T8709 T8706 arg1Of pathway,mitochondria-independent
R5982 T8709 T8708 arg1Of pathway,caspase-3-independent
R5983 T8709 T8710 arg1Of pathway,(
R5984 T8711 T8710 arg2Of Chiang,(
R5985 T8711 T8712 arg1Of Chiang,et
R5986 T8711 T8713 arg1Of Chiang,al.
R5987 T8711 T8714 arg1Of Chiang,","
R5988 T8715 T8714 arg2Of 2012,","
R5989 T8716 T8710 arg3Of ),(
R599 T1046 T1047 arg1Of mechanisms,are
R5990 T8720 T8718 arg1Of mechanisms,the
R5991 T8720 T8719 arg1Of mechanisms,underlying
R5992 T8720 T8721 arg1Of mechanisms,are
R5993 T8720 T8722 arg1Of mechanisms,unknown
R5994 T8721 T8717 arg2Of are,While
R5995 T8722 T8721 arg2Of unknown,are
R5996 T8725 T8717 arg1Of is,While
R5997 T8725 T8723 arg1Of is,","
R5998 T8726 T8725 arg2Of reasonable,is
R5999 T8728 T8724 arg1Of assume,it
R60 T197 T198 arg1Of resistance,to
R600 T1046 T1048 arg2Of mechanisms,involved
R6000 T8728 T8725 arg1Of assume,is
R6001 T8728 T8726 arg1Of assume,reasonable
R6002 T8728 T8727 arg1Of assume,to
R6003 T8731 T8730 arg1Of survival,the
R6004 T8731 T8732 arg1Of survival,of
R6005 T8731 T8736 arg1Of survival,depends
R6006 T8735 T8732 arg2Of cells,of
R6007 T8735 T8733 arg1Of cells,human
R6008 T8735 T8734 arg1Of cells,glioblastoma
R6009 T8736 T8728 arg2Of depends,assume
R601 T1048 T1047 arg2Of involved,are
R6010 T8736 T8729 arg1Of depends,that
R6011 T8736 T8737 arg1Of depends,upon
R6012 T8738 T8737 arg2Of interactions,upon
R6013 T8738 T8739 arg1Of interactions,between
R6014 T8741 T8739 arg2Of gain-of-function,between
R6015 T8741 T8740 arg1Of gain-of-function,the
R6016 T8741 T8742 arg1Of gain-of-function,of
R6017 T8744 T8743 arg1Of mutants,p53
R6018 T8744 T8745 arg1Of mutants,and
R6019 T8745 T8742 arg2Of and,of
R602 T1048 T1049 arg1Of involved,in
R6020 T8746 T8745 arg2Of WWOX,and
R6021 T8748 T8747 arg2Of WWOX,Activated
R6022 T8748 T8749 arg1Of WWOX,binds
R6023 T8749 T8756 arg1Of binds,(
R6024 T8752 T8749 arg2Of p53,binds
R6025 T8752 T8750 arg1Of p53,wild
R6026 T8752 T8751 arg1Of p53,type
R6027 T8752 T8753 arg1Of p53,with
R6028 T8755 T8753 arg2Of phosphorylation,with
R6029 T8755 T8754 arg1Of phosphorylation,Ser46
R603 T1052 T1049 arg2Of resistance,in
R6030 T8757 T8756 arg2Of Chang,(
R6031 T8757 T8758 arg1Of Chang,et
R6032 T8757 T8759 arg1Of Chang,al.
R6033 T8757 T8760 arg1Of Chang,","
R6034 T8761 T8760 arg2Of 2005b,","
R6035 T8762 T8756 arg3Of ),(
R6036 T8764 T8763 arg1Of irradiation,UV
R6037 T8764 T8765 arg1Of irradiation,enhances
R6038 T8768 T8765 arg2Of interactions,enhances
R6039 T8768 T8766 arg1Of interactions,the
R604 T1052 T1050 arg1Of resistance,the
R6040 T8768 T8767 arg1Of interactions,binding
R6041 T8771 T8769 arg2Of presence,Despite
R6042 T8771 T8770 arg1Of presence,the
R6043 T8771 T8772 arg1Of presence,of
R6044 T8771 T8774 arg1Of presence,in
R6045 T8773 T8772 arg2Of Ser46,of
R6046 T8775 T8774 arg2Of Δ40p53,in
R6047 T8777 T8778 arg1Of binding,of
R6048 T8777 T8783 arg1Of binding,remains
R6049 T8777 T8785 arg1Of binding,be
R605 T1052 T1051 arg1Of resistance,TMZ
R6050 T8777 T8786 arg2Of binding,determined
R6051 T8780 T8778 arg2Of protein,of
R6052 T8780 T8779 arg1Of protein,this
R6053 T8780 T8781 arg1Of protein,with
R6054 T8782 T8781 arg2Of WWOX,with
R6055 T8783 T8769 arg1Of remains,Despite
R6056 T8783 T8776 arg1Of remains,","
R6057 T8786 T8783 arg2Of determined,remains
R6058 T8786 T8784 arg1Of determined,to
R6059 T8786 T8785 arg2Of determined,be
R606 T1052 T1053 arg1Of resistance,","
R6060 T8787 T8788 arg1Of We,postulate
R6061 T8792 T8790 arg2Of cells,in
R6062 T8792 T8791 arg1Of cells,GBM
R6063 T8801 T8794 arg1Of proteins,both
R6064 T8801 T8795 arg1Of proteins,wild
R6065 T8801 T8796 arg1Of proteins,type
R6066 T8801 T8797 arg1Of proteins,p53
R6067 T8801 T8798 arg1Of proteins,and
R6068 T8801 T8799 arg1Of proteins,ectopic
R6069 T8801 T8800 arg1Of proteins,WWOX
R607 T1052 T1054 arg1Of resistance,which
R6070 T8801 T8802 arg1Of proteins,appear
R6071 T8801 T8804 arg1Of proteins,have
R6072 T8801 T8810 arg1Of proteins,nullifying
R6073 T8802 T8788 arg2Of appear,postulate
R6074 T8802 T8789 arg1Of appear,that
R6075 T8802 T8790 arg1Of appear,in
R6076 T8802 T8793 arg1Of appear,","
R6077 T8804 T8802 arg2Of have,appear
R6078 T8804 T8803 arg1Of have,to
R6079 T8804 T8808 arg1Of have,","
R608 T1052 T1055 arg1Of resistance,may
R6080 T8807 T8804 arg2Of antagonism,have
R6081 T8807 T8805 arg1Of antagonism,a
R6082 T8807 T8806 arg1Of antagonism,functional
R6083 T8810 T8804 arg3Of nullifying,have
R6084 T8810 T8809 arg1Of nullifying,thereby
R6085 T8812 T8811 arg1Of other’s,each
R6086 T8812 T8813 arg1Of other’s,function
R6087 T8812 T8815 arg1Of other’s,inducing
R6088 T8813 T8810 arg2Of function,nullifying
R6089 T8813 T8814 arg1Of function,in
R609 T1052 T1056 arg1Of resistance,include
R6090 T8815 T8814 arg2Of inducing,in
R6091 T8816 T8815 arg2Of apoptosis,inducing
R6092 T8816 T8817 arg1Of apoptosis,(
R6093 T8818 T8817 arg2Of Figure,(
R6094 T8818 T8819 arg1Of Figure,2
R6095 T8820 T8817 arg3Of ),(
R6096 T8823 T8821 arg1Of proteins,Mutant
R6097 T8823 T8822 arg1Of proteins,p53
R6098 T8823 T8824 arg1Of proteins,can
R6099 T8823 T8826 arg1Of proteins,bind
R61 T197 T203 arg1Of resistance,and
R610 T1056 T1055 arg2Of include,may
R6100 T8826 T8824 arg2Of bind,can
R6101 T8826 T8825 arg1Of bind,not
R6102 T8826 T8829 arg1Of bind,in
R6103 T8826 T8833 arg1Of bind,and
R6104 T8828 T8826 arg2Of WWOX,bind
R6105 T8828 T8827 arg1Of WWOX,ectopic
R6106 T8831 T8829 arg2Of cells,in
R6107 T8831 T8830 arg1Of cells,GBM
R6108 T8833 T8832 arg1Of and,","
R6109 T8834 T8835 arg1Of WWOX,is
R611 T1059 T1057 arg1Of cells,cancer
R6110 T8834 T8836 arg1Of WWOX,able
R6111 T8834 T8838 arg1Of WWOX,induce
R6112 T8835 T8833 arg2Of is,and
R6113 T8836 T8835 arg2Of able,is
R6114 T8838 T8836 arg2Of induce,able
R6115 T8838 T8837 arg1Of induce,to
R6116 T8839 T8838 arg2Of apoptosis,induce
R6117 T8841 T8842 arg1Of WWOX,causes
R6118 T8842 T8840 arg1Of causes,Whether
R6119 T8842 T8844 arg1Of causes,in
R612 T1059 T1058 arg1Of cells,stem
R6120 T8842 T8849 arg1Of causes,is
R6121 T8842 T8850 arg1Of causes,unknown
R6122 T8842 T8852 arg1Of causes,remains
R6123 T8842 T8854 arg1Of causes,be
R6124 T8842 T8855 arg2Of causes,established
R6125 T8843 T8842 arg2Of apoptosis,causes
R6126 T8848 T8844 arg2Of isoforms,in
R6127 T8848 T8845 arg1Of isoforms,GBM
R6128 T8848 T8846 arg1Of isoforms,expressing
R6129 T8848 T8847 arg1Of isoforms,p53
R613 T1059 T1060 arg1Of cells,","
R6130 T8849 T8851 arg1Of is,and
R6131 T8850 T8849 arg2Of unknown,is
R6132 T8852 T8851 arg2Of remains,and
R6133 T8855 T8852 arg2Of established,remains
R6134 T8855 T8853 arg1Of established,to
R6135 T8855 T8854 arg2Of established,be
R614 T1060 T1062 arg1Of ",",","
R615 T1061 T1060 arg2Of microRNAs,","
R616 T1062 T1065 arg1Of ",",","
R617 T1064 T1062 arg2Of efflux,","
R618 T1064 T1063 arg1Of efflux,drug
R619 T1065 T1069 arg1Of ",",","
R62 T199 T198 arg2Of temozolomide,to
R620 T1068 T1065 arg2Of repair,","
R621 T1068 T1066 arg1Of repair,DNA
R622 T1068 T1067 arg1Of repair,damage
R623 T1069 T1056 arg2Of ",",include
R624 T1069 T1072 arg1Of ",",under
R625 T1071 T1069 arg2Of cells,","
R626 T1071 T1070 arg1Of cells,tumor
R627 T1073 T1074 arg1Of hypoxia,","
R628 T1074 T1077 arg1Of ",",","
R629 T1076 T1074 arg2Of deacetylation,","
R63 T199 T200 arg1Of temozolomide,(
R630 T1076 T1075 arg1Of deacetylation,histone
R631 T1077 T1080 arg1Of ",",","
R632 T1079 T1077 arg2Of transition,","
R633 T1079 T1078 arg1Of transition,epithelial-mesenchymal
R634 T1080 T1084 arg1Of ",",and
R635 T1082 T1080 arg2Of kinase,","
R636 T1082 T1081 arg1Of kinase,STAT3
R637 T1084 T1072 arg2Of and,under
R638 T1084 T1083 arg1Of and,","
R639 T1086 T1084 arg2Of others,and
R64 T201 T200 arg2Of TMZ,(
R640 T1086 T1085 arg1Of others,many
R641 T1086 T1087 arg1Of others,(
R642 T1088 T1087 arg2Of Haar,(
R643 T1088 T1089 arg1Of Haar,et
R644 T1088 T1090 arg1Of Haar,al.
R645 T1088 T1091 arg1Of Haar,","
R646 T1088 T1093 arg1Of Haar,;
R647 T1088 T1099 arg1Of Haar,;
R648 T1092 T1091 arg2Of 2012,","
R649 T1094 T1093 arg2Of Happold,;
R65 T202 T200 arg3Of ),(
R650 T1094 T1095 arg1Of Happold,et
R651 T1094 T1096 arg1Of Happold,al.
R652 T1094 T1097 arg1Of Happold,","
R653 T1098 T1097 arg2Of 2012,","
R654 T1100 T1101 arg1Of Johannessen,and
R655 T1101 T1099 arg2Of and,;
R656 T1101 T1103 arg1Of and,","
R657 T1101 T1105 arg1Of and,;
R658 T1101 T1111 arg1Of and,;
R659 T1102 T1101 arg2Of Bjerkvig,and
R66 T203 T196 arg2Of and,to
R660 T1104 T1103 arg2Of 2012,","
R661 T1106 T1105 arg2Of Kitange,;
R662 T1106 T1107 arg1Of Kitange,et
R663 T1106 T1108 arg1Of Kitange,al.
R664 T1106 T1109 arg1Of Kitange,","
R665 T1110 T1109 arg2Of 2012,","
R666 T1112 T1111 arg2Of Kohsaka,;
R6669 T10070 T10071 arg1Of WWOX,affects
R667 T1112 T1113 arg1Of Kohsaka,et
R6670 T10071 T10069 arg1Of affects,Whether
R6671 T10071 T10074 arg1Of affects,has
R6672 T10071 T10076 arg1Of affects,been
R6673 T10071 T10077 arg2Of affects,determined
R6674 T10073 T10071 arg2Of sensitivity,affects
R6675 T10073 T10072 arg1Of sensitivity,TMZ
R6676 T10077 T10074 arg2Of determined,has
R6677 T10077 T10075 arg1Of determined,never
R6678 T10077 T10076 arg2Of determined,been
R6679 T10079 T10078 arg1Of proteins,Binding
R668 T1112 T1114 arg1Of Kohsaka,al.
R6680 T10079 T10080 arg1Of proteins,for
R6681 T10079 T10084 arg1Of proteins,are
R6682 T10079 T10085 arg1Of proteins,likely
R6683 T10081 T10082 arg1Of WWOX,and/or
R6684 T10082 T10080 arg2Of and/or,for
R6685 T10083 T10082 arg2Of p53,and/or
R6686 T10085 T10084 arg2Of likely,are
R6687 T10087 T10085 arg2Of affect,likely
R6688 T10087 T10086 arg1Of affect,to
R6689 T10088 T10089 arg1Of apoptosis,and
R669 T1112 T1115 arg1Of Kohsaka,","
R6690 T10089 T10087 arg2Of and,affect
R6691 T10089 T10092 arg1Of and,in
R6692 T10091 T10089 arg2Of sensitivity,and
R6693 T10091 T10090 arg1Of sensitivity,TMZ
R6694 T10094 T10092 arg2Of cells,in
R6695 T10094 T10093 arg1Of cells,GBM
R6696 T10095 T10096 arg1Of WWOX,binds
R6697 T10096 T10099 arg1Of binds,and
R6698 T10097 T10096 arg2Of MEK,binds
R6699 T10099 T10098 arg1Of and,","
R67 T205 T203 arg2Of drugs,and
R670 T1112 T1117 arg1Of Kohsaka,;
R6700 T10101 T10102 arg1Of PMA,dissociates
R6701 T10102 T10099 arg2Of dissociates,and
R6702 T10102 T10100 arg1Of dissociates,that
R6703 T10104 T10102 arg2Of complex,dissociates
R6704 T10104 T10103 arg1Of complex,this
R6705 T10104 T10105 arg1Of complex,for
R6706 T10106 T10105 arg2Of causing,for
R6707 T10106 T10112 arg1Of causing,(
R6708 T10107 T10106 arg2Of apoptosis,causing
R6709 T10107 T10108 arg1Of apoptosis,of
R671 T1116 T1115 arg2Of 2012,","
R6710 T10111 T10108 arg2Of cells,of
R6711 T10111 T10109 arg1Of cells,T
R6712 T10111 T10110 arg1Of cells,leukemia
R6713 T10113 T10112 arg2Of Lin,(
R6714 T10113 T10114 arg1Of Lin,et
R6715 T10113 T10115 arg1Of Lin,al.
R6716 T10113 T10116 arg1Of Lin,","
R6717 T10117 T10116 arg2Of 2011,","
R6718 T10118 T10112 arg3Of ),(
R6719 T10122 T10121 arg1Of chemicals,appropriate
R672 T1118 T1117 arg2Of Zhang,;
R6720 T10122 T10123 arg1Of chemicals,","
R6721 T10122 T10124 arg1Of chemicals,which
R6722 T10122 T10125 arg1Of chemicals,break
R6723 T10122 T10131 arg1Of chemicals,are
R6724 T10122 T10132 arg2Of chemicals,expected
R6725 T10122 T10134 arg1Of chemicals,cause
R6726 T10125 T10126 arg1Of break,apart
R6727 T10129 T10125 arg2Of complex,break
R6728 T10129 T10127 arg1Of complex,the
R6729 T10129 T10128 arg1Of complex,WWOX/MEK
R673 T1118 T1119 arg1Of Zhang,et
R6730 T10132 T10119 arg1Of expected,Thus
R6731 T10132 T10120 arg1Of expected,","
R6732 T10132 T10130 arg1Of expected,","
R6733 T10132 T10131 arg2Of expected,are
R6734 T10134 T10132 arg3Of cause,expected
R6735 T10134 T10133 arg1Of cause,to
R6736 T10137 T10134 arg2Of death,cause
R6737 T10137 T10135 arg1Of death,GBM
R6738 T10137 T10136 arg1Of death,cell
R6739 T10139 T10138 arg1Of studies,Preliminary
R674 T1118 T1120 arg1Of Zhang,al.
R6740 T10139 T10140 arg1Of studies,from
R6741 T10139 T10145 arg1Of studies,have
R6742 T10139 T10146 arg1Of studies,selected
R6743 T10142 T10140 arg2Of screening,from
R6744 T10142 T10141 arg1Of screening,our
R6745 T10142 T10143 arg1Of screening,of
R6746 T10144 T10143 arg2Of chemicals,of
R6747 T10146 T10145 arg2Of selected,have
R6748 T10149 T10146 arg2Of molecules,selected
R6749 T10149 T10147 arg1Of molecules,certain
R675 T1118 T1121 arg1Of Zhang,","
R6750 T10149 T10148 arg1Of molecules,small
R6751 T10149 T10150 arg1Of molecules,that
R6752 T10149 T10151 arg1Of molecules,induce
R6753 T10152 T10151 arg2Of apoptosis,induce
R6754 T10152 T10153 arg1Of apoptosis,of
R6755 T10155 T10153 arg2Of types,of
R6756 T10155 T10154 arg1Of types,many
R6757 T10155 T10156 arg1Of types,of
R6758 T10155 T10159 arg1Of types,(
R6759 T10158 T10156 arg2Of cells,of
R676 T1122 T1121 arg2Of 2012b,","
R6760 T10158 T10157 arg1Of cells,cancer
R6761 T10162 T10159 arg2Of al.,(
R6762 T10162 T10160 arg1Of al.,Lu
R6763 T10162 T10161 arg1Of al.,et
R6764 T10162 T10163 arg1Of al.,","
R6765 T10164 T10163 arg2Of unpublished,","
R6766 T10165 T10159 arg3Of ),(
R6767 T10169 T10168 arg1Of inhibition,specific
R6768 T10169 T10170 arg1Of inhibition,of
R6769 T10169 T10172 arg1Of inhibition,by
R677 T1123 T1087 arg3Of ),(
R6770 T10169 T10174 arg1Of inhibition,enhances
R6771 T10171 T10170 arg2Of MEK,of
R6772 T10173 T10172 arg2Of selumetinib,by
R6773 T10174 T10166 arg1Of enhances,Indeed
R6774 T10174 T10167 arg1Of enhances,","
R6775 T10174 T10181 arg1Of enhances,(
R6776 T10178 T10174 arg2Of death,enhances
R6777 T10178 T10175 arg1Of death,TMZ-induced
R6778 T10178 T10176 arg1Of death,cancer
R6779 T10178 T10177 arg1Of death,cell
R678 T1124 T1125 arg1Of Temozolomide,induces
R6780 T10178 T10180 arg1Of death,vivo
R6781 T10180 T10179 arg1Of vivo,in
R6782 T10182 T10181 arg2Of Holt,(
R6783 T10182 T10183 arg1Of Holt,et
R6784 T10182 T10184 arg1Of Holt,al.
R6785 T10182 T10185 arg1Of Holt,","
R6786 T10186 T10185 arg2Of 2012,","
R6787 T10187 T10181 arg3Of ),(
R6788 T10189 T10188 arg1Of factors,Serum
R6789 T10189 T10190 arg1Of factors,can
R679 T1126 T1125 arg2Of generation,induces
R6790 T10189 T10191 arg1Of factors,be
R6791 T10189 T10192 arg2Of factors,utilized
R6792 T10192 T10190 arg2Of utilized,can
R6793 T10192 T10191 arg2Of utilized,be
R6794 T10192 T10193 arg1Of utilized,for
R6795 T10194 T10193 arg2Of blocking,for
R6796 T10196 T10194 arg2Of growth,blocking
R6797 T10196 T10195 arg1Of growth,cancer
R6798 T10198 T10197 arg2Of example,For
R6799 T10202 T10200 arg1Of C1q,serum
R68 T205 T204 arg1Of drugs,therapeutic
R680 T1126 T1127 arg1Of generation,of
R6800 T10202 T10201 arg1Of C1q,complement
R6801 T10202 T10203 arg1Of C1q,induces
R6802 T10203 T10197 arg1Of induces,For
R6803 T10203 T10199 arg1Of induces,","
R6804 T10204 T10203 arg2Of apoptosis,induces
R6805 T10204 T10205 arg1Of apoptosis,of
R6806 T10204 T10211 arg1Of apoptosis,without
R6807 T10207 T10206 arg1Of cancer,prostate
R6808 T10207 T10208 arg1Of cancer,and
R6809 T10208 T10205 arg2Of and,of
R681 T1129 T1127 arg2Of lesions,of
R6810 T10210 T10208 arg2Of cells,and
R6811 T10210 T10209 arg1Of cells,neuroblastomas
R6812 T10212 T10211 arg2Of participation,without
R6813 T10212 T10213 arg1Of participation,of
R6814 T10215 T10213 arg2Of proteins,of
R6815 T10215 T10214 arg1Of proteins,downstream
R6816 T10215 T10216 arg1Of proteins,in
R6817 T10220 T10216 arg2Of pathway,in
R6818 T10220 T10217 arg1Of pathway,the
R6819 T10220 T10218 arg1Of pathway,classical
R682 T1129 T1128 arg1Of lesions,DNA
R6820 T10220 T10219 arg1Of pathway,activation
R6821 T10220 T10221 arg1Of pathway,(
R6822 T10222 T10221 arg2Of Hong,(
R6823 T10222 T10223 arg1Of Hong,et
R6824 T10222 T10224 arg1Of Hong,al.
R6825 T10222 T10225 arg1Of Hong,","
R6826 T10226 T10225 arg2Of 2009,","
R6827 T10227 T10221 arg3Of ),(
R6828 T10230 T10228 arg2Of event,In
R6829 T10230 T10229 arg1Of event,this
R683 T1129 T1130 arg1Of lesions,","
R6830 T10233 T10232 arg1Of WWOX,ectopic
R6831 T10233 T10234 arg1Of WWOX,is
R6832 T10233 T10235 arg2Of WWOX,activated
R6833 T10233 T10237 arg1Of WWOX,inducing
R6834 T10235 T10228 arg1Of activated,In
R6835 T10235 T10231 arg1Of activated,","
R6836 T10235 T10234 arg2Of activated,is
R6837 T10235 T10236 arg1Of activated,for
R6838 T10237 T10236 arg2Of inducing,for
R6839 T10238 T10237 arg2Of apoptosis,inducing
R684 T1129 T1131 arg1Of lesions,including
R6840 T10239 T10240 arg1Of Failure,of
R6841 T10239 T10243 arg1Of Failure,in
R6842 T10239 T10253 arg1Of Failure,is
R6843 T10239 T10254 arg1Of Failure,unusual
R6844 T10242 T10240 arg2Of WWOX,of
R6845 T10242 T10241 arg1Of WWOX,ectopic
R6846 T10244 T10243 arg2Of inducing,in
R6847 T10245 T10244 arg2Of apoptosis,inducing
R6848 T10245 T10246 arg1Of apoptosis,of
R6849 T10248 T10246 arg2Of cells,of
R685 T1132 T1133 arg1Of O6-methylguanine,","
R6850 T10248 T10247 arg1Of cells,glioma
R6851 T10248 T10249 arg1Of cells,possessing
R6852 T10252 T10249 arg2Of p53,possessing
R6853 T10252 T10250 arg1Of p53,wild
R6854 T10252 T10251 arg1Of p53,type
R6855 T10254 T10253 arg2Of unusual,is
R6856 T10254 T10255 arg1Of unusual,(
R6857 T10256 T10255 arg2Of Chiang,(
R6858 T10256 T10257 arg1Of Chiang,et
R6859 T10256 T10258 arg1Of Chiang,al.
R686 T1133 T1136 arg1Of ",",and
R6860 T10256 T10259 arg1Of Chiang,","
R6861 T10260 T10259 arg2Of 2012,","
R6862 T10261 T10255 arg3Of ),(
R6863 T10264 T10262 arg2Of cases,In
R6864 T10264 T10263 arg1Of cases,most
R6865 T10266 T10267 arg1Of we,have
R6866 T10266 T10268 arg1Of we,shown
R6867 T10268 T10262 arg1Of shown,In
R6868 T10268 T10265 arg1Of shown,","
R6869 T10268 T10267 arg2Of shown,have
R687 T1134 T1133 arg2Of N3-methyladenine,","
R6870 T10270 T10272 arg1Of p53,interacts
R6871 T10272 T10271 arg1Of interacts,functionally
R6872 T10272 T10273 arg1Of interacts,with
R6873 T10272 T10276 arg1Of interacts,and
R6874 T10274 T10273 arg2Of WWOX,with
R6875 T10276 T10268 arg2Of and,shown
R6876 T10276 T10269 arg1Of and,that
R6877 T10276 T10275 arg1Of and,","
R6878 T10278 T10277 arg1Of proteins,both
R6879 T10278 T10279 arg1Of proteins,induce
R688 T1136 T1131 arg2Of and,including
R6880 T10279 T10276 arg2Of induce,and
R6881 T10279 T10281 arg1Of induce,in
R6882 T10279 T10285 arg1Of induce,(
R6883 T10280 T10279 arg2Of apoptosis,induce
R6884 T10284 T10281 arg2Of manner,in
R6885 T10284 T10282 arg1Of manner,a
R6886 T10284 T10283 arg1Of manner,synergistic
R6887 T10286 T10287 arg1Of Chang,et
R6888 T10286 T10288 arg1Of Chang,al.
R6889 T10286 T10289 arg1Of Chang,","
R689 T1136 T1135 arg1Of and,","
R6890 T10289 T10291 arg1Of ",",","
R6891 T10290 T10289 arg2Of 2001,","
R6892 T10291 T10285 arg2Of ",",(
R6893 T10291 T10293 arg1Of ",",","
R6894 T10291 T10303 arg1Of ",",;
R6895 T10292 T10291 arg2Of 2003,","
R6896 T10294 T10295 arg1Of 2005a,","
R6897 T10295 T10297 arg1Of ",",","
R6898 T10296 T10295 arg2Of b,","
R6899 T10297 T10299 arg1Of ",",","
R69 T209 T206 arg1Of WWOX,WW
R690 T1136 T1138 arg1Of and,(
R6900 T10298 T10297 arg2Of 2007,","
R6901 T10299 T10301 arg1Of ",",","
R6902 T10300 T10299 arg2Of 2010,","
R6903 T10301 T10293 arg2Of ",",","
R6904 T10302 T10301 arg2Of 2012,","
R6905 T10304 T10303 arg2Of Su,;
R6906 T10304 T10305 arg1Of Su,et
R6907 T10304 T10306 arg1Of Su,al.
R6908 T10304 T10307 arg1Of Su,","
R6909 T10308 T10307 arg2Of 2012,","
R691 T1137 T1136 arg2Of N7-methylguanine,and
R6910 T10309 T10285 arg3Of ),(
R6911 T10312 T10310 arg1Of scenario,A
R6912 T10312 T10311 arg1Of scenario,likely
R6913 T10312 T10313 arg1Of scenario,is
R6914 T10316 T10315 arg1Of proteins,p53-binding
R6915 T10316 T10317 arg1Of proteins,","
R6916 T10316 T10318 arg1Of proteins,which
R6917 T10316 T10319 arg1Of proteins,are
R6918 T10316 T10320 arg1Of proteins,present
R6919 T10316 T10324 arg1Of proteins,may
R692 T1139 T1138 arg2Of Goellner,(
R6920 T10316 T10325 arg1Of proteins,interfere
R6921 T10320 T10319 arg2Of present,are
R6922 T10320 T10321 arg1Of present,in
R6923 T10322 T10321 arg2Of GBMs,in
R6924 T10325 T10313 arg2Of interfere,is
R6925 T10325 T10314 arg1Of interfere,that
R6926 T10325 T10323 arg1Of interfere,","
R6927 T10325 T10324 arg2Of interfere,may
R6928 T10325 T10326 arg1Of interfere,with
R6929 T10329 T10326 arg2Of function,with
R693 T1139 T1140 arg1Of Goellner,et
R6930 T10329 T10327 arg1Of function,the
R6931 T10329 T10328 arg1Of function,apoptotic
R6932 T10329 T10330 arg1Of function,of
R6933 T10331 T10332 arg1Of WWOX,and
R6934 T10332 T10330 arg2Of and,of
R6935 T10333 T10332 arg2Of p53,and
R6936 T10335 T10334 arg1Of antagonism,Functional
R6937 T10335 T10336 arg1Of antagonism,among
R6938 T10335 T10339 arg1Of antagonism,has
R6939 T10335 T10341 arg1Of antagonism,been
R694 T1139 T1141 arg1Of Goellner,al.
R6940 T10335 T10342 arg2Of antagonism,documented
R6941 T10338 T10336 arg2Of suppressors,among
R6942 T10338 T10337 arg1Of suppressors,tumor
R6943 T10342 T10339 arg2Of documented,has
R6944 T10342 T10340 arg1Of documented,never
R6945 T10342 T10341 arg2Of documented,been
R6946 T10342 T10343 arg1Of documented,in
R6947 T10345 T10343 arg2Of literature,in
R6948 T10345 T10344 arg1Of literature,the
R6949 T10349 T10346 arg1Of is,However
R695 T1139 T1142 arg1Of Goellner,","
R6950 T10349 T10347 arg1Of is,","
R6951 T10349 T10350 arg1Of is,not
R6952 T10351 T10349 arg2Of surprising,is
R6953 T10353 T10348 arg1Of find,it
R6954 T10353 T10349 arg1Of find,is
R6955 T10353 T10351 arg1Of find,surprising
R6956 T10353 T10352 arg1Of find,to
R6957 T10358 T10355 arg1Of proteins,many
R6958 T10358 T10356 arg1Of proteins,tumor
R6959 T10358 T10357 arg1Of proteins,suppressor
R696 T1139 T1144 arg1Of Goellner,;
R6960 T10358 T10359 arg1Of proteins,","
R6961 T10358 T10360 arg1Of proteins,e.g.
R6962 T10358 T10361 arg1Of proteins,","
R6963 T10358 T10375 arg1Of proteins,are
R6964 T10358 T10377 arg2Of proteins,upregulated
R6965 T10362 T10363 arg1Of p53,","
R6966 T10363 T10365 arg1Of ",",","
R6967 T10364 T10363 arg2Of WWOX,","
R6968 T10365 T10367 arg1Of ",",","
R6969 T10366 T10365 arg2Of Smad4,","
R697 T1143 T1142 arg2Of 2011,","
R6970 T10367 T10369 arg1Of ",",","
R6971 T10368 T10367 arg2Of PTEN,","
R6972 T10369 T10372 arg1Of ",",and
R6973 T10370 T10369 arg2Of PP2A,","
R6974 T10372 T10361 arg2Of and,","
R6975 T10372 T10371 arg1Of and,","
R6976 T10373 T10372 arg2Of etc.,and
R6977 T10377 T10353 arg2Of upregulated,find
R6978 T10377 T10354 arg1Of upregulated,that
R6979 T10377 T10374 arg1Of upregulated,","
R698 T1145 T1144 arg2Of Zhang,;
R6980 T10377 T10375 arg2Of upregulated,are
R6981 T10377 T10376 arg1Of upregulated,significantly
R6982 T10377 T10378 arg1Of upregulated,during
R6983 T10377 T10385 arg1Of upregulated,(
R6984 T10381 T10378 arg2Of stage,during
R6985 T10381 T10379 arg1Of stage,the
R6986 T10381 T10380 arg1Of stage,early
R6987 T10381 T10382 arg1Of stage,of
R6988 T10384 T10382 arg2Of progression,of
R6989 T10384 T10383 arg1Of progression,cancer
R699 T1145 T1146 arg1Of Zhang,et
R6990 T10386 T10385 arg2Of Lai,(
R6991 T10386 T10387 arg1Of Lai,et
R6992 T10386 T10388 arg1Of Lai,al.
R6993 T10386 T10389 arg1Of Lai,","
R6994 T10386 T10391 arg1Of Lai,;
R6995 T10390 T10389 arg2Of 2005,","
R6996 T10392 T10391 arg2Of Chang,;
R6997 T10392 T10393 arg1Of Chang,et
R6998 T10392 T10394 arg1Of Chang,al.
R6999 T10392 T10395 arg1Of Chang,","
R70 T209 T207 arg1Of WWOX,domain-containing
R700 T1145 T1147 arg1Of Zhang,al.
R7000 T10396 T10395 arg2Of unpublished,","
R7001 T10397 T10385 arg3Of ),(
R7002 T10399 T10398 arg2Of these,Do
R7003 T10400 T10401 arg1Of proteins,act
R7004 T10400 T10408 arg1Of proteins,lose
R7005 T10401 T10402 arg1Of act,synergistically
R7006 T10401 T10403 arg1Of act,in
R7007 T10401 T10407 arg1Of act,but
R7008 T10404 T10403 arg2Of blocking,in
R7009 T10406 T10404 arg2Of progression,blocking
R701 T1145 T1148 arg1Of Zhang,","
R7010 T10406 T10405 arg1Of progression,cancer
R7011 T10407 T10398 arg3Of but,Do
R7012 T10408 T10407 arg2Of lose,but
R7013 T10408 T10410 arg1Of lose,eventually
R7014 T10409 T10408 arg2Of control,lose
R7015 T10414 T10413 arg1Of they,do
R7016 T10414 T10415 arg1Of they,counteract
R7017 T10415 T10411 arg1Of counteract,Or
R7018 T10415 T10412 arg1Of counteract,","
R7019 T10415 T10413 arg2Of counteract,do
R702 T1149 T1148 arg2Of 2012b,","
R7020 T10415 T10419 arg1Of counteract,","
R7021 T10415 T10421 modOf counteract,allowing
R7022 T10418 T10415 arg2Of function,counteract
R7023 T10418 T10416 arg1Of function,each
R7024 T10418 T10417 arg1Of function,other’s
R7025 T10421 T10420 arg1Of allowing,thus
R7026 T10423 T10421 arg2Of growth,allowing
R7027 T10423 T10422 arg1Of growth,cancer
R7028 T10426 T10425 arg1Of WWOX,endogenous
R7029 T10426 T10427 arg1Of WWOX,counteracts
R703 T1150 T1138 arg3Of ),(
R7030 T10427 T10424 arg1Of counteracts,Whether
R7031 T10427 T10428 arg1Of counteracts,with
R7032 T10427 T10434 arg1Of counteracts,is
R7033 T10427 T10435 arg1Of counteracts,unknown
R7034 T10427 T10437 arg1Of counteracts,remains
R7035 T10427 T10439 arg1Of counteracts,be
R7036 T10427 T10440 arg2Of counteracts,established
R7037 T10430 T10428 arg2Of function,with
R7038 T10430 T10429 arg1Of function,the
R7039 T10430 T10431 arg1Of function,of
R704 T1153 T1151 arg1Of lesion,The
R7040 T10433 T10431 arg2Of p53,of
R7041 T10433 T10432 arg1Of p53,endogenous
R7042 T10434 T10436 arg1Of is,and
R7043 T10435 T10434 arg2Of unknown,is
R7044 T10437 T10436 arg2Of remains,and
R7045 T10440 T10437 arg2Of established,remains
R7046 T10440 T10438 arg1Of established,to
R7047 T10440 T10439 arg2Of established,be
R7048 T10441 T10442 arg1Of One,of
R7049 T10441 T10449 arg1Of One,is
R705 T1153 T1152 arg1Of lesion,O6-methylguanine
R7050 T10445 T10442 arg2Of characteristics,of
R7051 T10445 T10443 arg1Of characteristics,the
R7052 T10445 T10444 arg1Of characteristics,unique
R7053 T10445 T10446 arg1Of characteristics,for
R7054 T10448 T10446 arg2Of gliomas,for
R7055 T10448 T10447 arg1Of gliomas,malignant
R7056 T10452 T10449 arg2Of infiltration,is
R7057 T10452 T10450 arg1Of infiltration,their
R7058 T10452 T10451 arg1Of infiltration,diffuse
R7059 T10452 T10453 arg1Of infiltration,into
R706 T1153 T1154 arg1Of lesion,is
R7060 T10456 T10453 arg2Of tissue,into
R7061 T10456 T10454 arg1Of tissue,distant
R7062 T10456 T10455 arg1Of tissue,brain
R7063 T10458 T10457 arg1Of pathways,Signal
R7064 T10458 T10459 arg1Of pathways,","
R7065 T10458 T10460 arg1Of pathways,involving
R7066 T10458 T10472 arg1Of pathways,are
R7067 T10458 T10473 arg2Of pathways,believed
R7068 T10458 T10475 arg1Of pathways,confer
R7069 T10461 T10462 arg1Of PI3K,","
R707 T1153 T1155 arg2Of lesion,known
R7070 T10462 T10464 arg1Of ",",","
R7071 T10463 T10462 arg2Of Akt,","
R7072 T10464 T10466 arg1Of ",",","
R7073 T10465 T10464 arg2Of mTOR,","
R7074 T10466 T10469 arg1Of ",",and
R7075 T10467 T10466 arg2Of NF-κB,","
R7076 T10469 T10460 arg2Of and,involving
R7077 T10469 T10468 arg1Of and,","
R7078 T10470 T10469 arg2Of autophagy,and
R7079 T10473 T10471 arg1Of believed,","
R708 T1153 T1157 arg1Of lesion,trigger
R7080 T10473 T10472 arg2Of believed,are
R7081 T10475 T10473 arg3Of confer,believed
R7082 T10475 T10474 arg1Of confer,to
R7083 T10478 T10475 arg2Of cells,confer
R7084 T10478 T10476 arg1Of cells,these
R7085 T10478 T10477 arg1Of cells,migrating
R7086 T10478 T10479 arg1Of cells,resistant
R7087 T10479 T10480 arg1Of resistant,to
R7088 T10482 T10480 arg2Of death,to
R7089 T10482 T10481 arg1Of death,apoptotic
R709 T1155 T1154 arg2Of known,is
R7090 T10482 T10483 arg1Of death,(
R7091 T10484 T10483 arg2Of Lefranc,(
R7092 T10484 T10485 arg1Of Lefranc,et
R7093 T10484 T10486 arg1Of Lefranc,al.
R7094 T10484 T10487 arg1Of Lefranc,","
R7095 T10488 T10487 arg2Of 2005,","
R7096 T10489 T10483 arg3Of ),(
R7097 T10491 T10490 arg1Of cells,Glioma
R7098 T10491 T10492 arg1Of cells,possess
R7099 T10492 T10494 arg1Of possess,as
R71 T209 T208 arg1Of WWOX,oxidoreductase
R710 T1157 T1155 arg3Of trigger,known
R7100 T10493 T10492 arg2Of CD44,possess
R7101 T10496 T10497 arg1Of receptor,for
R7102 T10496 T10517 arg1Of receptor,and
R7103 T10498 T10497 arg2Of interacting,for
R7104 T10498 T10499 arg1Of interacting,with
R7105 T10498 T10503 arg1Of interacting,(
R7106 T10502 T10499 arg2Of hyaluronan,with
R7107 T10502 T10500 arg1Of hyaluronan,brain
R7108 T10502 T10501 arg1Of hyaluronan,matrix
R7109 T10504 T10503 arg2Of Murai,(
R711 T1157 T1156 arg1Of trigger,to
R7110 T10504 T10505 arg1Of Murai,et
R7111 T10504 T10506 arg1Of Murai,al.
R7112 T10504 T10507 arg1Of Murai,","
R7113 T10504 T10509 arg1Of Murai,;
R7114 T10508 T10507 arg2Of 2004,","
R7115 T10510 T10509 arg2Of Yoshida,;
R7116 T10510 T10511 arg1Of Yoshida,et
R7117 T10510 T10512 arg1Of Yoshida,al.
R7118 T10510 T10513 arg1Of Yoshida,","
R7119 T10514 T10513 arg2Of 2012,","
R712 T1157 T1163 arg1Of trigger,","
R7120 T10515 T10503 arg3Of ),(
R7121 T10517 T10494 arg2Of and,as
R7122 T10517 T10495 arg1Of and,a
R7123 T10517 T10516 arg1Of and,","
R7124 T10519 T10520 arg1Of hyaluronidases,and
R7125 T10520 T10517 arg2Of and,and
R7126 T10520 T10518 arg1Of and,secrete
R7127 T10520 T10522 modOf and,to
R7128 T10521 T10520 arg2Of metalloproteinases,and
R7129 T10523 T10522 arg1Of facilitate,to
R713 T1157 T1164 modOf trigger,to
R7130 T10523 T10526 arg1Of facilitate,(
R7131 T10525 T10523 arg2Of migration,facilitate
R7132 T10525 T10524 arg1Of migration,their
R7133 T10527 T10526 arg2Of Delpech,(
R7134 T10527 T10528 arg1Of Delpech,et
R7135 T10527 T10529 arg1Of Delpech,al.
R7136 T10527 T10530 arg1Of Delpech,","
R7137 T10527 T10532 arg1Of Delpech,;
R7138 T10527 T10538 arg1Of Delpech,;
R7139 T10531 T10530 arg2Of 2002,","
R714 T1157 T1168 arg1Of trigger,(
R7140 T10533 T10532 arg2Of Junker,;
R7141 T10533 T10534 arg1Of Junker,et
R7142 T10533 T10535 arg1Of Junker,al.
R7143 T10533 T10536 arg1Of Junker,","
R7144 T10537 T10536 arg2Of 2003,","
R7145 T10539 T10538 arg2Of Hagemann,;
R7146 T10539 T10540 arg1Of Hagemann,et
R7147 T10539 T10541 arg1Of Hagemann,al.
R7148 T10539 T10542 arg1Of Hagemann,","
R7149 T10543 T10542 arg2Of 2012,","
R715 T1158 T1161 arg1Of autophagy,than
R7150 T10544 T10526 arg3Of ),(
R7151 T10547 T10548 arg1Of lack,of
R7152 T10547 T10551 arg1Of lack,is
R7153 T10547 T10552 arg2Of lack,expected
R7154 T10547 T10554 arg1Of lack,enhance
R7155 T10550 T10548 arg2Of expression,of
R7156 T10550 T10549 arg1Of expression,WWOX
R7157 T10552 T10545 arg1Of expected,Also
R7158 T10552 T10546 arg1Of expected,","
R7159 T10552 T10551 arg2Of expected,is
R716 T1161 T1157 arg2Of than,trigger
R7160 T10554 T10552 arg3Of enhance,expected
R7161 T10554 T10553 arg1Of enhance,to
R7162 T10556 T10554 arg2Of migration,enhance
R7163 T10556 T10555 arg1Of migration,cell
R7164 T10558 T10557 arg2Of example,For
R7165 T10560 T10561 arg1Of loss,of
R7166 T10560 T10563 arg1Of loss,facilitates
R7167 T10562 T10561 arg2Of WWOX,of
R7168 T10563 T10557 arg1Of facilitates,For
R7169 T10563 T10559 arg1Of facilitates,","
R717 T1161 T1159 arg1Of than,","
R7170 T10563 T10571 arg1Of facilitates,(
R7171 T10564 T10563 arg2Of migration,facilitates
R7172 T10564 T10565 arg1Of migration,of
R7173 T10567 T10566 arg1Of cancer,ovarian
R7174 T10567 T10568 arg1Of cancer,and
R7175 T10568 T10565 arg2Of and,of
R7176 T10570 T10568 arg2Of cells,and
R7177 T10570 T10569 arg1Of cells,osteosarcoma
R7178 T10572 T10571 arg2Of Gourley,(
R7179 T10572 T10573 arg1Of Gourley,et
R718 T1161 T1160 arg1Of than,rather
R7180 T10572 T10574 arg1Of Gourley,al.
R7181 T10572 T10575 arg1Of Gourley,","
R7182 T10572 T10577 arg1Of Gourley,;
R7183 T10576 T10575 arg2Of 2009,","
R7184 T10579 T10577 arg2Of Mare,;
R7185 T10579 T10578 arg1Of Mare,Del
R7186 T10579 T10580 arg1Of Mare,et
R7187 T10579 T10581 arg1Of Mare,al.
R7188 T10579 T10582 arg1Of Mare,","
R7189 T10583 T10582 arg2Of 2011,","
R719 T1162 T1161 arg2Of apoptosis,than
R7190 T10584 T10571 arg3Of ),(
R7191 T10586 T10585 arg1Of expression,Ectopic
R7192 T10586 T10587 arg1Of expression,of
R7193 T10586 T10599 arg1Of expression,suppresses
R7194 T10586 T10606 arg1Of expression,causes
R7195 T10588 T10589 arg1Of TIAF1,(
R7196 T10588 T10594 arg1Of TIAF1,","
R7197 T10592 T10589 arg2Of factor,(
R7198 T10592 T10590 arg1Of factor,TGF-β-induced
R7199 T10592 T10591 arg1Of factor,antiapoptotic
R72 T209 T210 arg1Of WWOX,(
R720 T1165 T1164 arg1Of cause,to
R7200 T10593 T10589 arg3Of ),(
R7201 T10594 T10597 arg1Of ",",and
R7202 T10595 T10594 arg2Of p53,","
R7203 T10597 T10587 arg2Of and,of
R7204 T10597 T10596 arg1Of and,","
R7205 T10598 T10597 arg2Of WWOX,and
R7206 T10599 T10605 arg1Of suppresses,and
R7207 T10601 T10600 arg1Of growth,anchorage-independent
R7208 T10601 T10602 arg1Of growth,and
R7209 T10602 T10599 arg2Of and,suppresses
R721 T1167 T1165 arg2Of death,cause
R7210 T10604 T10602 arg2Of migration,and
R7211 T10604 T10603 arg1Of migration,cell
R7212 T10606 T10605 arg2Of causes,and
R7213 T10607 T10606 arg2Of apoptosis,causes
R7214 T10607 T10608 arg1Of apoptosis,in
R7215 T10610 T10608 arg2Of cells,in
R7216 T10610 T10609 arg1Of cells,cancer
R7217 T10610 T10611 arg1Of cells,(
R7218 T10612 T10611 arg2Of Chang,(
R7219 T10612 T10613 arg1Of Chang,et
R722 T1167 T1166 arg1Of death,cell
R7220 T10612 T10614 arg1Of Chang,al.
R7221 T10612 T10615 arg1Of Chang,","
R7222 T10616 T10615 arg2Of 2012,","
R7223 T10617 T10611 arg3Of ),(
R7224 T10618 T10619 arg1Of We,believe
R7225 T10622 T10621 arg1Of cells,glioma
R7226 T10622 T10623 arg1Of cells,","
R7227 T10622 T10624 arg1Of cells,with
R7228 T10622 T10629 arg1Of cells,migrate
R7229 T10627 T10624 arg2Of properties,with
R723 T1169 T1168 arg2Of Kanzawa,(
R7230 T10627 T10625 arg1Of properties,stem
R7231 T10627 T10626 arg1Of properties,cell-like
R7232 T10629 T10619 arg2Of migrate,believe
R7233 T10629 T10620 arg1Of migrate,that
R7234 T10629 T10628 arg1Of migrate,","
R7235 T10629 T10630 arg1Of migrate,individually
R7236 T10629 T10631 arg1Of migrate,rather
R7237 T10631 T10632 arg1Of rather,than
R7238 T10633 T10632 arg2Of collectively,than
R7239 T10635 T10634 arg1Of assumption,This
R724 T1169 T1170 arg1Of Kanzawa,et
R7240 T10635 T10636 arg1Of assumption,is
R7241 T10635 T10637 arg2Of assumption,based
R7242 T10637 T10636 arg2Of based,is
R7243 T10637 T10638 arg1Of based,upon
R7244 T10640 T10638 arg2Of observations,upon
R7245 T10640 T10639 arg1Of observations,our
R7246 T10646 T10642 arg1Of cells,mouse
R7247 T10646 T10643 arg1Of cells,Wwox
R7248 T10646 T10644 arg1Of cells,gene
R7249 T10646 T10645 arg1Of cells,knockout
R725 T1169 T1171 arg1Of Kanzawa,al.
R7250 T10646 T10647 arg1Of cells,(
R7251 T10646 T10653 arg1Of cells,migrate
R7252 T10651 T10647 arg2Of fibroblasts,(
R7253 T10651 T10648 arg1Of fibroblasts,e.g.
R7254 T10651 T10649 arg1Of fibroblasts,","
R7255 T10651 T10650 arg1Of fibroblasts,embryonic
R7256 T10652 T10647 arg3Of ),(
R7257 T10653 T10640 arg2Of migrate,observations
R7258 T10653 T10641 arg1Of migrate,that
R7259 T10653 T10654 arg1Of migrate,individually
R726 T1169 T1172 arg1Of Kanzawa,","
R7260 T10653 T10656 arg1Of migrate,aggressively
R7261 T10654 T10655 arg1Of individually,and
R7262 T10656 T10655 arg2Of aggressively,and
R7263 T10658 T10657 arg2Of contrast,In
R7264 T10662 T10660 arg1Of cells,wild
R7265 T10662 T10661 arg1Of cells,type
R7266 T10662 T10663 arg1Of cells,migrate
R7267 T10663 T10657 arg1Of migrate,In
R7268 T10663 T10659 arg1Of migrate,","
R7269 T10663 T10664 arg1Of migrate,collectively
R727 T1173 T1172 arg2Of 2003,","
R7270 T10663 T10665 arg1Of migrate,(
R7271 T10666 T10665 arg2Of Chou,(
R7272 T10666 T10667 arg1Of Chou,et
R7273 T10666 T10668 arg1Of Chou,al.
R7274 T10666 T10669 arg1Of Chou,","
R7275 T10670 T10669 arg2Of unpublished,","
R7276 T10671 T10665 arg3Of ),(
R7277 T10674 T10673 arg1Of portion,a
R7278 T10674 T10675 arg1Of portion,of
R7279 T10674 T10677 arg1Of portion,is
R728 T1174 T1168 arg3Of ),(
R7280 T10674 T10678 arg2Of portion,anchored
R7281 T10676 T10675 arg2Of WWOX,of
R7282 T10678 T10672 arg2Of anchored,While
R7283 T10678 T10677 arg2Of anchored,is
R7284 T10678 T10679 arg1Of anchored,on
R7285 T10682 T10679 arg2Of membrane/cytoskeleton,on
R7286 T10682 T10680 arg1Of membrane/cytoskeleton,the
R7287 T10682 T10681 arg1Of membrane/cytoskeleton,cell
R7288 T10685 T10684 arg1Of cells,WWOX-negative
R7289 T10685 T10686 arg1Of cells,lose
R729 T1177 T1178 arg1Of inhibition,of
R7290 T10686 T10672 arg1Of lose,While
R7291 T10686 T10683 arg1Of lose,","
R7292 T10686 T10688 arg1Of lose,by
R7293 T10686 T10693 arg1Of lose,and
R7294 T10687 T10686 arg2Of recognition,lose
R7295 T10691 T10688 arg2Of cells,by
R7296 T10691 T10689 arg1Of cells,parental
R7297 T10691 T10690 arg1Of cells,WWOX-positive
R7298 T10693 T10692 arg1Of and,","
R7299 T10694 T10695 arg1Of this,increases
R73 T209 T215 arg1Of WWOX,is
R730 T1177 T1181 arg1Of inhibition,by
R7300 T10695 T10693 arg2Of increases,and
R7301 T10697 T10695 arg2Of mobility,increases
R7302 T10697 T10696 arg1Of mobility,the
R7303 T10697 T10698 arg1Of mobility,of
R7304 T10697 T10701 modOf mobility,to
R7305 T10700 T10698 arg2Of cells,of
R7306 T10700 T10699 arg1Of cells,WWOX-negative
R7307 T10702 T10701 arg1Of move,to
R7308 T10702 T10703 arg1Of move,away
R7309 T10703 T10704 arg1Of away,from
R731 T1177 T1189 arg1Of inhibition,leads
R7310 T10707 T10704 arg2Of cells,from
R7311 T10707 T10705 arg1Of cells,the
R7312 T10707 T10706 arg1Of cells,WWOX-positive
R7313 T10712 T10710 arg1Of cells,WWOX-negative
R7314 T10712 T10711 arg1Of cells,glioma
R7315 T10712 T10713 arg1Of cells,migrate
R7316 T10712 T10716 arg1Of cells,turn
R7317 T10713 T10714 arg1Of migrate,individually
R7318 T10713 T10715 arg1Of migrate,and
R7319 T10715 T10708 arg1Of and,Conceivably
R732 T1177 T1196 arg1Of inhibition,enhances
R7320 T10715 T10709 arg1Of and,","
R7321 T10716 T10715 arg2Of turn,and
R7322 T10716 T10717 arg1Of turn,away
R7323 T10716 T10718 arg1Of turn,from
R7324 T10716 T10722 arg1Of turn,to
R7325 T10721 T10718 arg2Of cells,from
R7326 T10721 T10719 arg1Of cells,WWOX-expressing
R7327 T10721 T10720 arg1Of cells,brain
R7328 T10726 T10722 arg2Of areas,to
R7329 T10726 T10723 arg1Of areas,low
R733 T1180 T1178 arg2Of Bcl-2,of
R7330 T10726 T10724 arg1Of areas,WWOX
R7331 T10726 T10725 arg1Of areas,expression
R7332 T10731 T10729 arg1Of behavior,the
R7333 T10731 T10730 arg1Of behavior,migratory
R7334 T10731 T10732 arg1Of behavior,of
R7335 T10731 T10736 arg1Of behavior,may
R7336 T10731 T10737 arg1Of behavior,account
R7337 T10735 T10732 arg2Of cells,of
R7338 T10735 T10733 arg1Of cells,WWOX-negative
R7339 T10735 T10734 arg1Of cells,glioma
R734 T1180 T1179 arg1Of Bcl-2,antiapoptotic
R7340 T10737 T10727 arg1Of account,Apparently
R7341 T10737 T10728 arg1Of account,","
R7342 T10737 T10736 arg2Of account,may
R7343 T10737 T10738 arg1Of account,for
R7344 T10741 T10738 arg2Of invasion,for
R7345 T10741 T10739 arg1Of invasion,the
R7346 T10741 T10740 arg1Of invasion,diffuse
R7347 T10741 T10742 arg1Of invasion,into
R7348 T10745 T10742 arg2Of tissue,into
R7349 T10745 T10743 arg1Of tissue,distant
R735 T1184 T1182 arg1Of inhibitor,a
R7350 T10745 T10744 arg1Of tissue,brain
R7351 T10745 T10746 arg1Of tissue,(
R7352 T10747 T10746 arg2Of Chou,(
R7353 T10747 T10748 arg1Of Chou,et
R7354 T10747 T10749 arg1Of Chou,al.
R7355 T10747 T10750 arg1Of Chou,","
R7356 T10751 T10750 arg2Of unpublished,","
R7357 T10752 T10746 arg3Of ),(
R7358 T10754 T10753 arg1Of alterations,Metabolic
R7359 T10754 T10755 arg1Of alterations,have
R736 T1184 T1183 arg1Of inhibitor,pan-Bcl-2
R7360 T10754 T10756 arg1Of alterations,been
R7361 T10754 T10757 arg2Of alterations,shown
R7362 T10757 T10755 arg2Of shown,have
R7363 T10757 T10756 arg2Of shown,been
R7364 T10757 T10758 arg1Of shown,in
R7365 T10761 T10758 arg2Of mice,in
R7366 T10761 T10759 arg1Of mice,Wwox
R7367 T10761 T10760 arg1Of mice,knockout
R7368 T10761 T10762 arg1Of mice,","
R7369 T10761 T10763 arg1Of mice,including
R737 T1186 T1184 arg1Of −,inhibitor
R7370 T10765 T10764 arg1Of lethality,postnatal
R7371 T10765 T10766 arg1Of lethality,","
R7372 T10766 T10770 arg1Of ",",","
R7373 T10769 T10766 arg2Of defects,","
R7374 T10769 T10767 arg1Of defects,bone
R7375 T10769 T10768 arg1Of defects,metabolism
R7376 T10770 T10772 arg1Of ",",","
R7377 T10771 T10770 arg2Of ataxia,","
R7378 T10772 T10775 arg1Of ",",and
R7379 T10773 T10772 arg2Of steroidogenesis,","
R738 T1186 T1185 arg1Of −,(
R7380 T10775 T10763 arg2Of and,including
R7381 T10775 T10774 arg1Of and,","
R7382 T10775 T10779 arg1Of and,(
R7383 T10776 T10775 arg2Of generation,and
R7384 T10776 T10777 arg1Of generation,of
R7385 T10778 T10777 arg2Of osteosarcomas,of
R7386 T10781 T10779 arg2Of Mare,(
R7387 T10781 T10780 arg1Of Mare,Del
R7388 T10781 T10782 arg1Of Mare,et
R7389 T10781 T10783 arg1Of Mare,al.
R739 T1186 T1187 arg1Of −,)
R7390 T10781 T10784 arg1Of Mare,","
R7391 T10781 T10786 arg1Of Mare,;
R7392 T10785 T10784 arg2Of 2011,","
R7393 T10787 T10786 arg2Of Salah,;
R7394 T10787 T10788 arg1Of Salah,et
R7395 T10787 T10789 arg1Of Salah,al.
R7396 T10787 T10790 arg1Of Salah,","
R7397 T10791 T10790 arg2Of 2012,","
R7398 T10792 T10779 arg3Of ),(
R7399 T10796 T10793 arg2Of model,In
R74 T209 T220 arg1Of WWOX,is
R740 T1188 T1181 arg2Of -gossypol,by
R7400 T10796 T10794 arg1Of model,a
R7401 T10796 T10795 arg1Of model,Drosophila
R7402 T10798 T10799 arg1Of Wwox,is
R7403 T10798 T10800 arg2Of Wwox,shown
R7404 T10798 T10802 arg1Of Wwox,participate
R7405 T10800 T10793 arg1Of shown,In
R7406 T10800 T10797 arg1Of shown,","
R7407 T10800 T10799 arg2Of shown,is
R7408 T10802 T10800 arg3Of participate,shown
R7409 T10802 T10801 arg1Of participate,to
R741 T1188 T1186 arg1Of -gossypol,−
R7410 T10802 T10803 arg1Of participate,in
R7411 T10804 T10803 arg2Of pathways,in
R7412 T10804 T10805 arg1Of pathways,involving
R7413 T10807 T10806 arg1Of metabolism,aerobic
R7414 T10807 T10808 arg1Of metabolism,and
R7415 T10808 T10805 arg2Of and,involving
R7416 T10808 T10811 arg1Of and,for
R7417 T10810 T10808 arg2Of stress,and
R7418 T10810 T10809 arg1Of stress,oxidative
R7419 T10812 T10811 arg2Of generation,for
R742 T1189 T1190 arg1Of leads,to
R7420 T10812 T10813 arg1Of generation,of
R7421 T10814 T10813 arg2Of ROS,of
R7422 T10814 T10815 arg1Of ROS,(
R7423 T10816 T10815 arg2Of O’Keefe,(
R7424 T10816 T10817 arg1Of O’Keefe,et
R7425 T10816 T10818 arg1Of O’Keefe,al.
R7426 T10816 T10819 arg1Of O’Keefe,","
R7427 T10820 T10819 arg2Of 2011,","
R7428 T10821 T10815 arg3Of ),(
R7429 T10824 T10822 arg2Of stress,Under
R743 T1189 T1195 arg1Of leads,and
R7430 T10824 T10823 arg1Of stress,UV
R7431 T10827 T10830 modOf Wwox,induces
R7432 T10827 T10833 arg1Of Wwox,in
R7433 T10829 T10828 arg1Of expression,gene
R7434 T10829 T10830 arg1Of expression,induces
R7435 T10832 T10830 arg2Of production,induces
R7436 T10832 T10831 arg1Of production,ROS
R7437 T10834 T10826 arg1Of Drosophila.,functional
R7438 T10834 T10827 arg1Of Drosophila.,Wwox
R7439 T10834 T10837 modOf Drosophila.,are
R744 T1192 T1190 arg2Of death,to
R7440 T10836 T10835 arg1Of cells,Cancer
R7441 T10836 T10837 arg1Of cells,are
R7442 T10836 T10838 arg2Of cells,known
R7443 T10836 T10841 arg1Of cells,utilize
R7444 T10838 T10837 arg2Of known,are
R7445 T10841 T10838 arg3Of utilize,known
R7446 T10841 T10839 arg1Of utilize,to
R7447 T10841 T10840 arg1Of utilize,overly
R7448 T10842 T10841 arg2Of glycolysis,utilize
R7449 T10845 T10834 arg1Of advantage,Drosophila.
R745 T1192 T1191 arg1Of death,autophagic
R7450 T10845 T10843 arg1Of advantage,for
R7451 T10845 T10844 arg1Of advantage,growth
R7452 T10845 T10846 arg1Of advantage,–
R7453 T10846 T10822 arg1Of –,Under
R7454 T10846 T10825 arg1Of –,","
R7455 T10849 T10846 arg2Of Warburg,–
R7456 T10849 T10847 arg1Of Warburg,the
R7457 T10849 T10848 arg1Of Warburg,so-called
R7458 T10849 T10850 arg1Of Warburg,(
R7459 T10851 T10850 arg2Of Moncada,(
R746 T1192 T1193 arg1Of death,in
R7460 T10851 T10852 arg1Of Moncada,et
R7461 T10851 T10853 arg1Of Moncada,al.
R7462 T10851 T10854 arg1Of Moncada,","
R7463 T10855 T10854 arg2Of 2012,","
R7464 T10856 T10850 arg3Of ),(
R7465 T10859 T10860 arg1Of WWOX,is
R7466 T10859 T10861 arg1Of WWOX,likely
R7467 T10859 T10863 arg1Of WWOX,override
R7468 T10859 T10870 arg1Of WWOX,exerts
R7469 T10860 T10869 arg1Of is,and
R747 T1194 T1193 arg2Of gliomas,in
R7470 T10861 T10860 arg2Of likely,is
R7471 T10863 T10861 arg2Of override,likely
R7472 T10863 T10862 arg1Of override,to
R7473 T10865 T10863 arg2Of consumption,override
R7474 T10865 T10864 arg1Of consumption,glucose
R7475 T10865 T10866 arg1Of consumption,in
R7476 T10868 T10866 arg2Of cells,in
R7477 T10868 T10867 arg1Of cells,cancer
R7478 T10869 T10857 arg1Of and,Conceivably
R7479 T10869 T10858 arg1Of and,","
R748 T1195 T1175 arg1Of and,Also
R7480 T10870 T10869 arg2Of exerts,and
R7481 T10871 T10870 arg2Of generation,exerts
R7482 T10871 T10872 arg1Of generation,of
R7483 T10871 T10874 modOf generation,to
R7484 T10873 T10872 arg2Of ROS,of
R7485 T10875 T10874 arg1Of curb,to
R7486 T10879 T10880 arg1Of growth,and
R7487 T10880 T10875 arg2Of and,curb
R7488 T10880 T10876 arg1Of and,the
R7489 T10880 T10877 arg1Of and,cancer
R749 T1195 T1176 arg1Of and,","
R7490 T10880 T10878 arg1Of and,cell
R7491 T10881 T10880 arg2Of invasion,and
R7492 T10883 T10882 arg2Of summary,In
R7493 T10888 T10885 arg2Of article,in
R7494 T10888 T10886 arg1Of article,this
R7495 T10888 T10887 arg1Of article,perspective
R7496 T10889 T10890 arg1Of we,have
R7497 T10889 T10891 arg1Of we,discussed
R7498 T10891 T10882 arg1Of discussed,In
R7499 T10891 T10884 arg1Of discussed,","
R75 T209 T221 arg2Of WWOX,considered
R750 T1196 T1195 arg2Of enhances,and
R7500 T10891 T10885 arg1Of discussed,in
R7501 T10891 T10890 arg2Of discussed,have
R7502 T10894 T10891 arg2Of role,discussed
R7503 T10894 T10892 arg1Of role,the
R7504 T10894 T10893 arg1Of role,potential
R7505 T10894 T10895 arg1Of role,of
R7506 T10894 T10901 arg1Of role,in
R7507 T10898 T10899 arg1Of p53,and
R7508 T10899 T10895 arg2Of and,of
R7509 T10899 T10896 arg1Of and,tumor
R751 T1196 T1201 arg1Of enhances,(
R7510 T10899 T10897 arg1Of and,suppressors
R7511 T10900 T10899 arg2Of WWOX,and
R7512 T10902 T10901 arg2Of regulating,in
R7513 T10904 T10902 arg2Of sensitivity,regulating
R7514 T10904 T10903 arg1Of sensitivity,TMZ
R7515 T10904 T10905 arg1Of sensitivity,in
R7516 T10907 T10905 arg2Of cells,in
R7517 T10907 T10906 arg1Of cells,GBM
R7518 T10908 T10909 arg1Of We,have
R7519 T10908 T10910 arg1Of We,shown
R752 T1198 T1196 arg2Of action,enhances
R7520 T10908 T10924 arg1Of We,discussed
R7521 T10910 T10909 arg2Of shown,have
R7522 T10910 T10923 arg1Of shown,and
R7523 T10912 T10910 arg2Of role,shown
R7524 T10912 T10911 arg1Of role,the
R7525 T10912 T10913 arg1Of role,of
R7526 T10912 T10915 arg1Of role,in
R7527 T10914 T10913 arg2Of WWOX,of
R7528 T10916 T10915 arg2Of controlling,in
R7529 T10918 T10917 arg1Of migration,cell
R753 T1198 T1197 arg1Of action,the
R7530 T10918 T10919 arg1Of migration,and
R7531 T10919 T10916 arg2Of and,controlling
R7532 T10921 T10919 arg2Of alterations,and
R7533 T10921 T10920 arg1Of alterations,metabolic
R7534 T10923 T10922 arg1Of and,","
R7535 T10924 T10923 arg2Of discussed,and
R7536 T10926 T10924 arg2Of effects,discussed
R7537 T10926 T10925 arg1Of effects,the
R7538 T10926 T10927 arg1Of effects,of
R7539 T10929 T10928 arg1Of deficiency,WWOX
R754 T1198 T1199 arg1Of action,of
R7540 T10929 T10930 arg1Of deficiency,and
R7541 T10930 T10927 arg2Of and,of
R7542 T10930 T10933 arg1Of and,in
R7543 T10932 T10930 arg2Of resistance,and
R7544 T10932 T10931 arg1Of resistance,TMZ
R7545 T10935 T10933 arg2Of cells,in
R7546 T10935 T10934 arg1Of cells,cancer
R755 T1200 T1199 arg2Of TMZ,of
R756 T1202 T1201 arg2Of Voss,(
R757 T1202 T1203 arg1Of Voss,et
R758 T1202 T1204 arg1Of Voss,al.
R759 T1202 T1205 arg1Of Voss,","
R76 T211 T212 arg1Of FOR,or
R760 T1206 T1205 arg2Of 2010,","
R761 T1207 T1201 arg3Of ),(
R762 T1212 T1210 arg1Of study,a
R763 T1212 T1211 arg1Of study,recent
R764 T1212 T1213 arg1Of study,demonstrated
R765 T1213 T1208 arg1Of demonstrated,However
R766 T1213 T1209 arg1Of demonstrated,","
R767 T1216 T1215 arg1Of autophagy,TMZ-induced
R768 T1216 T1217 arg1Of autophagy,is
R769 T1216 T1218 arg1Of autophagy,pro-survival
R77 T212 T210 arg2Of or,(
R770 T1216 T1221 arg1Of autophagy,may
R771 T1216 T1222 arg1Of autophagy,block
R772 T1217 T1220 arg1Of is,and
R773 T1218 T1217 arg2Of pro-survival,is
R774 T1220 T1213 arg2Of and,demonstrated
R775 T1220 T1214 arg1Of and,that
R776 T1220 T1219 arg1Of and,","
R777 T1222 T1220 arg2Of block,and
R778 T1222 T1221 arg2Of block,may
R779 T1222 T1229 arg1Of block,(
R78 T213 T212 arg2Of WOX1,or
R780 T1225 T1222 arg2Of apoptosis,block
R781 T1225 T1223 arg1Of apoptosis,the
R782 T1225 T1224 arg1Of apoptosis,eventual
R783 T1225 T1226 arg1Of apoptosis,in
R784 T1228 T1226 arg2Of cells,in
R785 T1228 T1227 arg1Of cells,GBM
R786 T1230 T1229 arg2Of Knizhnik,(
R787 T1230 T1231 arg1Of Knizhnik,et
R788 T1230 T1232 arg1Of Knizhnik,al.
R789 T1230 T1233 arg1Of Knizhnik,","
R79 T214 T210 arg3Of ),(
R790 T1234 T1233 arg2Of 2013,","
R791 T1235 T1229 arg3Of ),(
R792 T1240 T1239 arg2Of C1orf201,(
R793 T1241 T1239 arg3Of ),(
R794 T1242 T1238 arg1Of gene,MAPO2
R795 T1242 T1239 arg1Of gene,(
R796 T1242 T1243 arg1Of gene,participates
R797 T1243 T1236 arg1Of participates,Also
R798 T1243 T1237 arg1Of participates,","
R799 T1243 T1244 arg1Of participates,in
R80 T215 T219 arg1Of is,and
R800 T1243 T1249 arg1Of participates,(
R801 T1248 T1244 arg2Of apoptosis,in
R802 T1248 T1245 arg1Of apoptosis,the
R803 T1248 T1246 arg1Of apoptosis,O6-methylguanine
R804 T1248 T1247 arg1Of apoptosis,lesion-induced
R805 T1250 T1249 arg2Of Fujikane,(
R806 T1250 T1251 arg1Of Fujikane,et
R807 T1250 T1252 arg1Of Fujikane,al.
R808 T1250 T1253 arg1Of Fujikane,","
R809 T1254 T1253 arg2Of 2012,","
R81 T218 T215 arg2Of protein,is
R810 T1255 T1249 arg3Of ),(
R811 T1257 T1256 arg1Of gene,MAPO2
R812 T1257 T1258 arg1Of gene,encodes
R813 T1262 T1258 arg2Of protein,encodes
R814 T1262 T1259 arg1Of protein,a
R815 T1262 T1260 arg1Of protein,novel
R816 T1262 T1261 arg1Of protein,37-kDa
R817 T1263 T1264 arg1Of It,is
R818 T1263 T1266 arg2Of It,determined
R819 T1266 T1264 arg2Of determined,is
R82 T218 T216 arg1Of protein,a
R820 T1266 T1265 arg1Of determined,not
R821 T1266 T1267 arg1Of determined,whether
R822 T1269 T1268 arg1Of gene,this
R823 T1269 T1270 arg1Of gene,is
R824 T1269 T1271 arg2Of gene,involved
R825 T1271 T1267 arg2Of involved,whether
R826 T1271 T1270 arg2Of involved,is
R827 T1271 T1272 arg1Of involved,in
R828 T1273 T1272 arg2Of autophagy,in
R829 T1276 T1274 arg1Of lesion,The
R83 T218 T217 arg1Of protein,proapoptotic
R830 T1276 T1275 arg1Of lesion,O6-methylguanine
R831 T1276 T1277 arg1Of lesion,is
R832 T1277 T1289 arg1Of is,(
R833 T1279 T1277 arg2Of substrate,is
R834 T1279 T1278 arg1Of substrate,a
R835 T1279 T1280 arg1Of substrate,for
R836 T1279 T1283 arg1Of substrate,by
R837 T1282 T1280 arg2Of repair,for
R838 T1282 T1281 arg1Of repair,direct
R839 T1285 T1283 arg2Of methyltransferase,by
R84 T221 T219 arg2Of considered,and
R840 T1285 T1284 arg1Of methyltransferase,O6-methylguanine-DNA
R841 T1285 T1286 arg1Of methyltransferase,(
R842 T1287 T1286 arg2Of MGMT,(
R843 T1288 T1286 arg3Of ),(
R844 T1290 T1289 arg2Of Pollack,(
R845 T1290 T1291 arg1Of Pollack,et
R846 T1290 T1292 arg1Of Pollack,al.
R847 T1290 T1293 arg1Of Pollack,","
R848 T1290 T1295 arg1Of Pollack,;
R849 T1290 T1301 arg1Of Pollack,;
R85 T221 T220 arg2Of considered,is
R850 T1294 T1293 arg2Of 2006,","
R851 T1296 T1295 arg2Of Hegi,;
R852 T1296 T1297 arg1Of Hegi,et
R853 T1296 T1298 arg1Of Hegi,al.
R854 T1296 T1299 arg1Of Hegi,","
R855 T1300 T1299 arg2Of 2008,","
R856 T1302 T1301 arg2Of Fukushima,;
R857 T1302 T1303 arg1Of Fukushima,et
R858 T1302 T1304 arg1Of Fukushima,al.
R859 T1302 T1305 arg1Of Fukushima,","
R86 T221 T222 arg1Of considered,as
R860 T1302 T1307 arg1Of Fukushima,;
R8607 T12473 T12472 arg1Of Chiang,Ming-Fu
R8608 T12473 T12474 arg1Of Chiang,and
R8609 T12474 T12477 arg1Of and,wrote
R861 T1306 T1305 arg2Of 2009,","
R8610 T12476 T12474 arg2Of Sze,and
R8611 T12476 T12475 arg1Of Sze,Chun-I
R8612 T12477 T12483 arg1Of wrote,;
R8613 T12479 T12477 arg2Of sections,wrote
R8614 T12479 T12478 arg1Of sections,the
R8615 T12479 T12480 arg1Of sections,dealing
R8616 T12480 T12481 arg1Of dealing,with
R8617 T12482 T12481 arg2Of TMZ,with
R8618 T12485 T12484 arg1Of Chou,Pei-Yi
R8619 T12485 T12486 arg1Of Chou,wrote
R862 T1308 T1307 arg2Of Zhang,;
R8620 T12486 T12483 arg2Of wrote,;
R8621 T12486 T12497 arg1Of wrote,;
R8622 T12489 T12486 arg2Of sections,wrote
R8623 T12489 T12487 arg1Of sections,the
R8624 T12489 T12488 arg1Of sections,review
R8625 T12489 T12490 arg1Of sections,for
R8626 T12491 T12492 arg1Of p53,and
R8627 T12492 T12494 arg1Of and,and
R8628 T12493 T12492 arg2Of WWOX,and
R8629 T12494 T12490 arg2Of and,for
R863 T1308 T1309 arg1Of Zhang,et
R8630 T12496 T12494 arg2Of graphs,and
R8631 T12496 T12495 arg2Of graphs,designed
R8632 T12499 T12498 arg1Of Wang,Wan-Jen
R8633 T12499 T12500 arg1Of Wang,managed
R8634 T12500 T12497 arg2Of managed,;
R8635 T12500 T12502 arg1Of managed,;
R8636 T12501 T12500 arg2Of citations,managed
R8637 T12504 T12503 arg1Of Chang,Nan-Shan
R8638 T12504 T12505 arg1Of Chang,conceived
R8639 T12504 T12508 arg1Of Chang,wrote
R864 T1308 T1310 arg1Of Zhang,al.
R8640 T12504 T12511 arg1Of Chang,revised
R8641 T12504 T12516 arg2Of Chang,discussed
R8642 T12505 T12507 arg1Of conceived,","
R8643 T12506 T12505 arg2Of ideas,conceived
R8644 T12507 T12509 arg1Of ",",and
R8645 T12508 T12507 arg2Of wrote,","
R8646 T12509 T12515 arg1Of and,and
R8647 T12511 T12509 arg2Of revised,and
R8648 T12511 T12510 arg1Of revised,thoroughly
R8649 T12513 T12511 arg2Of manuscript,revised
R865 T1308 T1311 arg1Of Zhang,","
R8650 T12513 T12512 arg1Of manuscript,the
R8651 T12515 T12502 arg2Of and,;
R8652 T12515 T12514 arg1Of and,","
R8653 T12516 T12515 arg2Of discussed,and
R8654 T12516 T12517 arg1Of discussed,with
R8655 T12518 T12517 arg2Of coauthors,with
R866 T1312 T1311 arg2Of 2012b,","
R867 T1313 T1289 arg3Of ),(
R868 T1316 T1314 arg2Of repair,Without
R869 T1316 T1315 arg1Of repair,MGMT
R87 T225 T222 arg2Of suppressor,as
R870 T1318 T1319 arg1Of O6-methylguanine,initiates
R8704 T12592 T12591 arg1Of authors,The
R8705 T12592 T12593 arg1Of authors,declare
R8706 T12596 T12595 arg1Of research,the
R8707 T12596 T12597 arg1Of research,was
R8708 T12596 T12598 arg2Of research,conducted
R8709 T12598 T12593 arg2Of conducted,declare
R871 T1319 T1314 arg1Of initiates,Without
R8710 T12598 T12594 arg1Of conducted,that
R8711 T12598 T12597 arg2Of conducted,was
R8712 T12598 T12599 arg1Of conducted,in
R8713 T12599 T12600 arg1Of in,the
R8714 T12599 T12602 arg1Of in,of
R8715 T12601 T12599 arg2Of absence,in
R8716 T12604 T12605 arg1Of commercial,or
R8717 T12606 T12605 arg2Of financial,or
R8718 T12607 T12599 arg3Of relationships,in
R8719 T12607 T12603 arg1Of relationships,any
R872 T1319 T1317 arg1Of initiates,","
R8720 T12607 T12604 arg1Of relationships,commercial
R8721 T12607 T12606 arg1Of relationships,financial
R8722 T12607 T12608 arg1Of relationships,that
R8723 T12607 T12609 arg1Of relationships,could
R8724 T12607 T12610 arg1Of relationships,be
R8725 T12607 T12611 arg2Of relationships,construed
R8726 T12611 T12609 arg2Of construed,could
R8727 T12611 T12610 arg2Of construed,be
R8728 T12611 T12612 arg1Of construed,as
R8729 T12615 T12612 arg2Of conflict,as
R873 T1320 T1321 arg1Of activation,of
R8730 T12615 T12613 arg1Of conflict,a
R8731 T12615 T12614 arg1Of conflict,potential
R8732 T12615 T12616 arg1Of conflict,of
R8733 T12617 T12616 arg2Of interest,of
R874 T1320 T1328 arg1Of activation,or
R875 T1325 T1324 arg2Of MMR,(
R876 T1326 T1324 arg3Of ),(
R877 T1327 T1321 arg2Of proteins,of
R878 T1327 T1322 arg1Of proteins,mismatch
R879 T1327 T1323 arg1Of proteins,repair-deficient
R88 T225 T223 arg1Of suppressor,a
R880 T1327 T1324 arg1Of proteins,(
R881 T1328 T1319 arg2Of or,initiates
R882 T1331 T1328 arg2Of kinase,or
R883 T1331 T1329 arg1Of kinase,Rad3-related
R884 T1331 T1330 arg1Of kinase,protein
R885 T1331 T1332 arg1Of kinase,that
R886 T1331 T1334 arg1Of kinase,leads
R887 T1334 T1333 arg1Of leads,ultimately
R888 T1334 T1335 arg1Of leads,to
R889 T1334 T1339 arg1Of leads,(
R89 T225 T224 arg1Of suppressor,tumor
R890 T1338 T1335 arg2Of death,to
R891 T1338 T1336 arg1Of death,apoptotic
R892 T1338 T1337 arg1Of death,cell
R893 T1340 T1339 arg2Of Caporali,(
R894 T1340 T1341 arg1Of Caporali,et
R895 T1340 T1342 arg1Of Caporali,al.
R896 T1340 T1343 arg1Of Caporali,","
R897 T1340 T1345 arg1Of Caporali,;
R898 T1340 T1351 arg1Of Caporali,;
R8982 T13044 T13043 arg1Of diagrams,Schematic
R8983 T13044 T13045 arg1Of diagrams,of
R8984 T13044 T13048 arg1Of diagrams,and
R8985 T13047 T13045 arg2Of structure,of
R8986 T13047 T13046 arg1Of structure,WWOX
R8987 T13050 T13048 arg2Of role,and
R8988 T13050 T13049 arg1Of role,its
R8989 T13050 T13051 arg1Of role,in
R899 T1344 T1343 arg2Of 2004,","
R8990 T13052 T13051 arg2Of signaling,in
R8991 T13053 T13054 arg1Of WWOX,contains
R8992 T13058 T13055 arg1Of domains,two
R8993 T13058 T13056 arg1Of domains,N-terminal
R8994 T13058 T13057 arg1Of domains,WW
R8995 T13058 T13059 arg1Of domains,","
R8996 T13058 T13070 arg1Of domains,and
R8997 T13066 T13065 arg2Of SDR,(
R8998 T13067 T13065 arg3Of ),(
R8999 T13068 T13059 arg2Of domain,","
R90 T226 T227 arg1Of Loss,of
R900 T1346 T1347 arg1Of Wang,and
R9000 T13068 T13060 arg1Of domain,a
R9001 T13068 T13061 arg1Of domain,C-terminal
R9002 T13068 T13062 arg1Of domain,short-chain
R9003 T13068 T13063 arg1Of domain,alcohol
R9004 T13068 T13064 arg1Of domain,dehydrogenase/reductase
R9005 T13068 T13065 arg1Of domain,(
R9006 T13070 T13054 arg2Of and,contains
R9007 T13070 T13069 arg1Of and,","
R9008 T13073 T13070 arg2Of region,and
R9009 T13073 T13071 arg1Of region,a
R901 T1347 T1345 arg2Of and,;
R9010 T13073 T13072 arg1Of region,D3
R9011 T13077 T13074 arg1Of signal,A
R9012 T13077 T13075 arg1Of signal,nuclear
R9013 T13077 T13076 arg1Of signal,localization
R9014 T13077 T13078 arg1Of signal,(
R9015 T13077 T13081 arg1Of signal,is
R9016 T13077 T13083 arg1Of signal,between
R9017 T13079 T13078 arg2Of NLS,(
R9018 T13080 T13078 arg3Of ),(
R9019 T13081 T13087 arg1Of is,(
R902 T1347 T1349 arg1Of and,","
R9020 T13083 T13081 arg2Of between,is
R9021 T13083 T13082 arg1Of between,in
R9022 T13086 T13083 arg2Of domains,between
R9023 T13086 T13084 arg1Of domains,the
R9024 T13086 T13085 arg1Of domains,WW
R9025 T13088 T13089 arg1Of Chang,et
R9026 T13088 T13090 arg1Of Chang,al.
R9027 T13088 T13091 arg1Of Chang,","
R9028 T13091 T13093 arg1Of ",",","
R9029 T13092 T13091 arg2Of 2003,","
R903 T1348 T1347 arg2Of Edelmann,and
R9030 T13093 T13095 arg1Of ",",;
R9031 T13094 T13093 arg2Of 2007,","
R9032 T13095 T13102 arg1Of ;,;
R9033 T13097 T13096 arg1Of Mare,Del
R9034 T13097 T13098 arg1Of Mare,et
R9035 T13097 T13099 arg1Of Mare,al.
R9036 T13097 T13100 arg1Of Mare,","
R9037 T13100 T13095 arg2Of ",",;
R9038 T13101 T13100 arg2Of 2011,","
R9039 T13102 T13087 arg2Of ;,(
R904 T1350 T1349 arg2Of 2006,","
R9040 T13102 T13114 arg1Of ;,;
R9041 T13103 T13104 arg1Of Salah,et
R9042 T13103 T13105 arg1Of Salah,al.
R9043 T13103 T13106 arg1Of Salah,","
R9044 T13106 T13108 arg1Of ",",;
R9045 T13107 T13106 arg2Of 2012,","
R9046 T13108 T13112 arg1Of ;,","
R9047 T13109 T13108 arg2Of Su,;
R9048 T13109 T13110 arg1Of Su,et
R9049 T13109 T13111 arg1Of Su,al.
R905 T1352 T1351 arg2Of Roos,;
R9050 T13112 T13102 arg2Of ",",;
R9051 T13113 T13112 arg2Of 2012,","
R9052 T13115 T13114 arg2Of reviews,;
R9053 T13116 T13087 arg3Of ),(
R9054 T13119 T13117 arg1Of domain,The
R9055 T13119 T13118 arg1Of domain,SDR
R9056 T13119 T13120 arg1Of domain,possesses
R9057 T13123 T13120 arg2Of region,possesses
R9058 T13123 T13121 arg1Of region,a
R9059 T13123 T13122 arg1Of region,mitochondria-binding
R906 T1352 T1353 arg1Of Roos,et
R9060 T13124 T13125 arg1Of There,are
R9061 T13130 T13125 arg2Of sites,are
R9062 T13130 T13126 arg1Of sites,two
R9063 T13130 T13127 arg2Of sites,conserved
R9064 T13130 T13128 arg1Of sites,tyrosine
R9065 T13130 T13129 arg1Of sites,phosphorylation
R9066 T13130 T13131 arg1Of sites,","
R9067 T13132 T13133 arg1Of Tyr33,and
R9068 T13133 T13131 arg2Of and,","
R9069 T13134 T13133 arg2Of Tyr287,and
R907 T1352 T1354 arg1Of Roos,al.
R9070 T13137 T13135 arg1Of sites,Other
R9071 T13137 T13136 arg1Of sites,phosphorylation
R9072 T13137 T13138 arg2Of sites,predicted
R9073 T13137 T13143 arg1Of sites,are
R9074 T13142 T13138 arg1Of Server,predicted
R9075 T13142 T13139 arg2Of Server,by
R9076 T13142 T13140 arg1Of Server,NetPhos
R9077 T13142 T13141 arg1Of Server,2.0
R9078 T13143 T13156 arg1Of are,","
R9079 T13143 T13157 arg1Of are,respectively
R908 T1352 T1355 arg1Of Roos,","
R9080 T13144 T13145 arg1Of Tyr6,","
R9081 T13145 T13147 arg1Of ",",","
R9082 T13146 T13145 arg2Of Thr12,","
R9083 T13147 T13149 arg1Of ",",","
R9084 T13148 T13147 arg2Of Ser14,","
R9085 T13149 T13151 arg1Of ",",","
R9086 T13150 T13149 arg2Of Tyr61,","
R9087 T13151 T13154 arg1Of ",",and
R9088 T13152 T13151 arg2Of Tyr293,","
R9089 T13154 T13143 arg2Of and,are
R909 T1356 T1355 arg2Of 2007,","
R9090 T13154 T13153 arg1Of and,","
R9091 T13155 T13154 arg2Of Thr3B3,and
R9092 T13160 T13158 arg2Of stimulation,Upon
R9093 T13160 T13159 arg1Of stimulation,stress
R9094 T13162 T13163 arg1Of WWOX,is
R9095 T13162 T13164 arg2Of WWOX,phosphorylated
R9096 T13162 T13168 arg1Of WWOX,binds
R9097 T13164 T13163 arg2Of phosphorylated,is
R9098 T13164 T13165 arg1Of phosphorylated,in
R9099 T13164 T13167 arg1Of phosphorylated,and
R91 T226 T231 arg1Of Loss,is
R910 T1357 T1339 arg3Of ),(
R9100 T13166 T13165 arg2Of Tyr33,in
R9101 T13167 T13158 arg1Of and,Upon
R9102 T13167 T13161 arg1Of and,","
R9103 T13168 T13167 arg2Of binds,and
R9104 T13169 T13168 arg2Of p53,binds
R9105 T13172 T13170 arg1Of complex,The
R9106 T13172 T13171 arg1Of complex,WWOX/p53
R9107 T13172 T13174 arg1Of complex,translocates
R9108 T13174 T13173 arg1Of translocates,then
R9109 T13174 T13175 arg1Of translocates,to
R911 T1359 T1358 arg1Of expression,High
R9110 T13176 T13177 arg1Of mitochondria,or
R9111 T13177 T13175 arg2Of or,to
R9112 T13177 T13179 modOf or,to
R9113 T13178 T13177 arg2Of nucleus,or
R9114 T13180 T13179 arg1Of induce,to
R9115 T13181 T13180 arg2Of apoptosis,induce
R9116 T13182 T13184 arg1Of WWOX,binds
R9117 T13184 T13183 arg1Of binds,also
R9118 T13184 T13205 arg1Of binds,and
R9119 T13188 T13184 arg2Of factors,binds
R912 T1359 T1360 arg1Of expression,of
R9120 T13188 T13185 arg1Of factors,PPxY
R9121 T13188 T13186 arg1Of factors,motif-containing
R9122 T13188 T13187 arg1Of factors,transcription
R9123 T13188 T13189 arg1Of factors,","
R9124 T13188 T13191 arg1Of factors,as
R9125 T13191 T13190 arg1Of as,such
R9126 T13192 T13193 arg1Of RUNX2,","
R9127 T13193 T13196 arg1Of ",",and
R9128 T13194 T13193 arg2Of c-Jun,","
R9129 T13196 T13191 arg2Of and,as
R913 T1359 T1366 arg1Of expression,contributes
R9130 T13196 T13195 arg1Of and,","
R9131 T13196 T13198 arg1Of and,","
R9132 T13196 T13199 arg1Of and,via
R9133 T13197 T13196 arg2Of ERBB4,and
R9134 T13203 T13199 arg2Of domain,via
R9135 T13203 T13200 arg1Of domain,its
R9136 T13203 T13201 arg1Of domain,first
R9137 T13203 T13202 arg1Of domain,WW
R9138 T13205 T13204 arg1Of and,","
R9139 T13207 T13206 arg1Of binding,the
R914 T1361 T1362 arg1Of MGMT,or
R9140 T13207 T13208 arg1Of binding,blocks
R9141 T13207 T13215 arg1Of binding,retaining
R9142 T13208 T13205 arg2Of blocks,and
R9143 T13208 T13214 arg1Of blocks,by
R9144 T13210 T13208 arg2Of activity,blocks
R9145 T13210 T13209 arg1Of activity,the
R9146 T13210 T13211 arg1Of activity,of
R9147 T13213 T13211 arg2Of proteins,of
R9148 T13213 T13212 arg1Of proteins,these
R9149 T13215 T13214 arg2Of retaining,by
R915 T1362 T1360 arg2Of or,of
R9150 T13215 T13217 arg1Of retaining,in
R9151 T13216 T13215 arg2Of them,retaining
R9152 T13219 T13217 arg2Of cytoplasm,in
R9153 T13219 T13218 arg1Of cytoplasm,the
R9154 T13220 T13221 arg1Of WWOX,binds
R9155 T13221 T13223 arg1Of binds,via
R9156 T13222 T13221 arg2Of Tau,binds
R9157 T13226 T13223 arg2Of domain,via
R9158 T13226 T13224 arg1Of domain,its
R9159 T13226 T13225 arg1Of domain,SDR
R916 T1363 T1362 arg2Of loss,or
R9160 T13227 T13228 arg1Of WWOX,participates
R9161 T13227 T13235 arg1Of WWOX,binding
R9162 T13227 T13238 arg1Of WWOX,inhibiting
R9163 T13228 T13229 arg1Of participates,in
R9164 T13228 T13234 arg1Of participates,by
R9165 T13233 T13229 arg2Of pathway,in
R9166 T13233 T13230 arg1Of pathway,the
R9167 T13233 T13231 arg1Of pathway,Wnt/β-catenin
R9168 T13233 T13232 arg1Of pathway,signal
R9169 T13235 T13237 arg1Of binding,and
R917 T1363 T1364 arg1Of loss,of
R9170 T13236 T13235 arg2Of Dvl,binding
R9171 T13237 T13234 arg2Of and,by
R9172 T13238 T13237 arg2Of inhibiting,and
R9173 T13241 T13238 arg2Of import,inhibiting
R9174 T13241 T13239 arg1Of import,its
R9175 T13241 T13240 arg1Of import,nuclear
R9176 T13243 T13242 arg1Of ester,Phorbol
R9177 T13243 T13244 arg1Of ester,stimulates
R9178 T13244 T13255 arg1Of stimulates,and
R9179 T13246 T13244 arg2Of dissociation,stimulates
R918 T1365 T1364 arg2Of MMR,of
R9180 T13246 T13245 arg1Of dissociation,the
R9181 T13246 T13247 arg1Of dissociation,of
R9182 T13249 T13247 arg2Of complex,of
R9183 T13249 T13248 arg1Of complex,MEK/WWOX
R9184 T13249 T13250 arg1Of complex,in
R9185 T13253 T13250 arg2Of cell,in
R9186 T13253 T13251 arg1Of cell,Jurkat
R9187 T13253 T13252 arg1Of cell,T
R9188 T13255 T13254 arg1Of and,","
R9189 T13258 T13256 arg1Of WWOX,the
R919 T1366 T1367 arg1Of contributes,significantly
R9190 T13258 T13257 arg2Of WWOX,released
R9191 T13258 T13259 arg1Of WWOX,translocates
R9192 T13259 T13255 arg2Of translocates,and
R9193 T13259 T13260 arg1Of translocates,to
R9194 T13262 T13260 arg2Of mitochondria,to
R9195 T13262 T13261 arg1Of mitochondria,the
R9196 T13262 T13263 arg1Of mitochondria,for
R9197 T13264 T13263 arg2Of causing,for
R9198 T13266 T13264 arg2Of death,causing
R9199 T13266 T13265 arg1Of death,cell
R92 T226 T233 arg2Of Loss,seen
R920 T1366 T1368 arg1Of contributes,to
R9200 T13267 T13268 arg1Of WWOX,is
R9201 T13267 T13269 arg2Of WWOX,recruited
R9202 T13269 T13268 arg2Of recruited,is
R9203 T13269 T13270 arg1Of recruited,to
R9204 T13269 T13274 arg1Of recruited,by
R9205 T13269 T13278 arg1Of recruited,and
R9206 T13273 T13270 arg2Of area,to
R9207 T13273 T13271 arg1Of area,the
R9208 T13273 T13272 arg1Of area,membrane
R9209 T13275 T13274 arg2Of association,by
R921 T1366 T1371 arg1Of contributes,in
R9210 T13275 T13276 arg1Of association,with
R9211 T13277 T13276 arg2Of Hyal-2,with
R9212 T13280 T13279 arg1Of Hyal-2,phospho-Ezrin.
R9213 T13280 T13281 arg1Of Hyal-2,is
R9214 T13281 T13278 arg2Of is,and
R9215 T13284 T13281 arg2Of receptor,is
R9216 T13284 T13282 arg1Of receptor,an
R9217 T13284 T13283 arg1Of receptor,alternative
R9218 T13284 T13285 arg1Of receptor,for
R9219 T13286 T13285 arg2Of TGF-β1,for
R922 T1366 T1375 arg1Of contributes,(
R9220 T13288 T13287 arg2Of response,In
R9221 T13288 T13289 arg1Of response,to
R9222 T13290 T13289 arg2Of TGF-β1,to
R9223 T13292 T13293 arg1Of WWOX,binds
R9224 T13292 T13296 arg1Of WWOX,forms
R9225 T13293 T13295 arg1Of binds,and
R9226 T13294 T13293 arg2Of Hyal-2,binds
R9227 T13295 T13287 arg1Of and,In
R9228 T13295 T13291 arg1Of and,","
R9229 T13295 T13299 arg1Of and,","
R923 T1370 T1368 arg2Of resistance,to
R9230 T13295 T13300 modOf and,followed
R9231 T13296 T13295 arg2Of forms,and
R9232 T13298 T13296 arg2Of complex,forms
R9233 T13298 T13297 arg1Of complex,a
R9234 T13300 T13301 arg1Of followed,by
R9235 T13302 T13303 arg1Of relocating,to
R9236 T13302 T13306 arg1Of relocating,and
R9237 T13305 T13303 arg2Of nucleus,to
R9238 T13305 T13304 arg1Of nucleus,the
R9239 T13306 T13301 arg2Of and,by
R924 T1370 T1369 arg1Of resistance,TMZ
R9240 T13307 T13306 arg2Of enhancing,and
R9241 T13311 T13307 arg2Of activity,enhancing
R9242 T13311 T13308 arg1Of activity,the
R9243 T13311 T13309 arg1Of activity,SMAD-driven
R9244 T13311 T13310 arg1Of activity,promoter
R9245 T13312 T13313 arg1Of Ack1,","
R9246 T13312 T13318 arg1Of Ack1,;
R9247 T13316 T13313 arg2Of kinase,","
R9248 T13316 T13314 arg2Of kinase,activated
R9249 T13316 T13315 arg1Of kinase,Cdc42-associated
R925 T1374 T1371 arg2Of cases,in
R9250 T13316 T13317 arg1Of kinase,1
R9251 T13319 T13318 arg2Of Hyal-2,;
R9252 T13319 T13320 arg1Of Hyal-2,","
R9253 T13319 T13323 arg1Of Hyal-2,;
R9254 T13321 T13320 arg2Of hyaluronoglucosaminidase,","
R9255 T13321 T13322 arg1Of hyaluronoglucosaminidase,2
R9256 T13324 T13323 arg2Of CKI,;
R9257 T13324 T13325 arg1Of CKI,","
R9258 T13324 T13328 arg1Of CKI,;
R9259 T13327 T13325 arg2Of kinase,","
R926 T1374 T1372 arg1Of cases,many
R9260 T13327 T13326 arg1Of kinase,casein
R9261 T13329 T13328 arg2Of GSK,;
R9262 T13329 T13330 arg1Of GSK,","
R9263 T13329 T13334 arg1Of GSK,;
R9264 T13333 T13330 arg2Of kinase,","
R9265 T13333 T13331 arg1Of kinase,glycogen
R9266 T13333 T13332 arg1Of kinase,synthase
R9267 T13335 T13334 arg2Of PKA,;
R9268 T13335 T13336 arg1Of PKA,","
R9269 T13339 T13336 arg2Of A,","
R927 T1374 T1373 arg1Of cases,clinical
R9270 T13339 T13337 arg1Of A,protein
R9271 T13339 T13338 arg1Of A,kinase
R928 T1376 T1375 arg2Of Pollack,(
R929 T1376 T1377 arg1Of Pollack,et
R93 T230 T227 arg2Of expression,of
R930 T1376 T1378 arg1Of Pollack,al.
R931 T1376 T1379 arg1Of Pollack,","
R932 T1376 T1381 arg1Of Pollack,;
R933 T1376 T1387 arg1Of Pollack,;
R934 T1380 T1379 arg2Of 2006,","
R935 T1382 T1381 arg2Of Hegi,;
R936 T1382 T1383 arg1Of Hegi,et
R937 T1382 T1384 arg1Of Hegi,al.
R938 T1382 T1385 arg1Of Hegi,","
R939 T1386 T1385 arg2Of 2008,","
R94 T230 T228 arg1Of expression,WWOX
R940 T1388 T1387 arg2Of Sarkaria,;
R941 T1388 T1389 arg1Of Sarkaria,et
R942 T1388 T1390 arg1Of Sarkaria,al.
R943 T1388 T1391 arg1Of Sarkaria,","
R944 T1392 T1391 arg2Of 2008,","
R945 T1393 T1375 arg3Of ),(
R946 T1395 T1394 arg1Of initiation,The
R947 T1395 T1396 arg1Of initiation,of
R948 T1395 T1399 arg1Of initiation,fails
R949 T1398 T1396 arg2Of signaling,of
R95 T230 T229 arg1Of expression,gene
R950 T1398 T1397 arg1Of signaling,apoptotic
R951 T1399 T1400 arg1Of fails,in
R952 T1400 T1401 arg1Of in,the
R953 T1400 T1403 arg1Of in,of
R954 T1402 T1400 arg2Of absence,in
R955 T1406 T1400 arg3Of system,in
R956 T1406 T1404 arg1Of system,the
R957 T1406 T1405 arg1Of system,MMR
R958 T1407 T1408 arg1Of Sensitivity,to
R959 T1407 T1410 arg1Of Sensitivity,is
R96 T233 T231 arg2Of seen,is
R960 T1407 T1412 arg2Of Sensitivity,associated
R961 T1409 T1408 arg2Of TMZ,to
R962 T1412 T1410 arg2Of associated,is
R963 T1412 T1411 arg1Of associated,significantly
R964 T1412 T1413 arg1Of associated,with
R965 T1416 T1413 arg2Of status,with
R966 T1416 T1414 arg1Of status,the
R967 T1416 T1415 arg1Of status,methylation
R968 T1416 T1417 arg1Of status,of
R969 T1420 T1417 arg2Of promoter,of
R97 T233 T232 arg1Of seen,frequently
R970 T1420 T1418 arg1Of promoter,MGMT
R9708 T14173 T14174 arg1Of p53,and
R9709 T14174 T14176 arg1Of and,in
R971 T1420 T1419 arg1Of promoter,gene
R9710 T14174 T14185 arg1Of and,possesses
R9711 T14175 T14174 arg2Of WWOX,and
R9712 T14181 T14180 arg2Of A,(
R9713 T14182 T14180 arg3Of ),(
R9714 T14184 T14176 arg2Of p53,in
R9715 T14184 T14177 arg1Of p53,GBM
R9716 T14184 T14178 arg1Of p53,cell
R9717 T14184 T14179 arg1Of p53,apoptosis.
R9718 T14184 T14180 arg1Of p53,(
R9719 T14184 T14183 arg1Of p53,Full-length
R972 T1420 T1421 arg1Of promoter,in
R9720 T14190 T14186 arg1Of domains,two
R9721 T14190 T14187 arg1Of domains,N-terminal
R9722 T14190 T14188 arg1Of domains,transactivation
R9723 T14190 T14189 arg1Of domains,acidic
R9724 T14190 T14191 arg1Of domains,","
R9725 T14190 T14195 arg1Of domains,","
R9726 T14190 T14201 arg1Of domains,and
R9727 T14194 T14191 arg2Of domain,","
R9728 T14194 T14192 arg1Of domain,a
R9729 T14194 T14193 arg1Of domain,proline-rich
R973 T1422 T1421 arg2Of cells,in
R9730 T14199 T14195 arg2Of region,","
R9731 T14199 T14196 arg1Of region,a
R9732 T14199 T14197 arg1Of region,central
R9733 T14199 T14198 arg1Of region,DNA-binding
R9734 T14201 T14200 arg1Of and,","
R9735 T14201 T14216 arg1Of and,and
R9736 T14204 T14201 arg2Of domain,and
R9737 T14204 T14202 arg1Of domain,a
R9738 T14204 T14203 arg1Of domain,C-terminal
R9739 T14204 T14205 arg1Of domain,","
R974 T1422 T1423 arg2Of cells,committed
R9740 T14204 T14206 arg1Of domain,containing
R9741 T14204 T14211 arg1Of domain,","
R9742 T14210 T14206 arg2Of signal,containing
R9743 T14210 T14207 arg1Of signal,a
R9744 T14210 T14208 arg1Of signal,nuclear
R9745 T14210 T14209 arg1Of signal,localization
R9746 T14214 T14211 arg2Of domain,","
R9747 T14214 T14212 arg1Of domain,an
R9748 T14214 T14213 arg1Of domain,oligomerization
R9749 T14216 T14185 arg2Of and,possesses
R975 T1423 T1424 arg1Of committed,to
R9750 T14216 T14215 arg1Of and,","
R9751 T14219 T14216 arg2Of region,and
R9752 T14219 T14217 arg1Of region,a
R9753 T14219 T14218 arg1Of region,basic
R9754 T14222 T14220 arg1Of mutants,N-terminal
R9755 T14222 T14221 arg1Of mutants,deletion
R9756 T14222 T14223 arg1Of mutants,of
R9757 T14222 T14225 arg1Of mutants,are
R9758 T14224 T14223 arg2Of p53,of
R9759 T14225 T14226 arg1Of are,also
R976 T1425 T1424 arg2Of differentiation,to
R9760 T14227 T14225 arg2Of shown.,are
R9761 T14227 T14228 arg1Of shown.,(
R9762 T14227 T14234 modOf shown.,are
R9763 T14229 T14228 arg2Of B,(
R9764 T14230 T14228 arg3Of ),(
R9765 T14233 T14231 arg1Of scenarios,Three
R9766 T14233 T14232 arg1Of scenarios,likely
R9767 T14233 T14234 arg1Of scenarios,are
R9768 T14233 T14235 arg2Of scenarios,proposed
R9769 T14235 T14234 arg2Of proposed,are
R977 T1425 T1426 arg1Of differentiation,(
R9770 T14235 T14236 arg1Of proposed,for
R9771 T14237 T14238 arg1Of WWOX,and
R9772 T14238 T14236 arg2Of and,for
R9773 T14238 T14240 modOf and,to
R9774 T14239 T14238 arg2Of p53,and
R9775 T14241 T14240 arg1Of regulate,to
R9776 T14244 T14241 arg2Of death,regulate
R9777 T14244 T14242 arg1Of death,GBM
R9778 T14244 T14243 arg1Of death,cell
R9779 T14248 T14247 arg1Of WWOX,ectopic
R978 T1429 T1426 arg2Of al.,(
R9780 T14248 T14249 arg1Of WWOX,fails
R9781 T14248 T14251 arg1Of WWOX,induce
R9782 T14249 T14245 arg1Of fails,First
R9783 T14249 T14246 arg1Of fails,","
R9784 T14251 T14249 arg2Of induce,fails
R9785 T14251 T14250 arg1Of induce,to
R9786 T14252 T14251 arg2Of apoptosis,induce
R9787 T14252 T14253 arg1Of apoptosis,of
R9788 T14255 T14253 arg2Of cells,of
R9789 T14255 T14254 arg1Of cells,GBM
R979 T1429 T1427 arg1Of al.,Villalva
R9790 T14255 T14256 arg1Of cells,expressing
R9791 T14260 T14256 arg2Of p53,expressing
R9792 T14260 T14257 arg1Of p53,endogenous
R9793 T14260 T14258 arg1Of p53,wild
R9794 T14260 T14259 arg1Of p53,type
R9795 T14261 T14262 arg1Of It,appears
R9796 T14265 T14264 arg1Of WWOX,ectopic
R9797 T14265 T14266 arg1Of WWOX,binds
R9798 T14265 T14269 arg1Of WWOX,antagonizes
R9799 T14266 T14267 arg1Of binds,and
R98 T233 T234 arg1Of seen,in
R980 T1429 T1428 arg1Of al.,et
R9800 T14267 T14272 arg1Of and,and
R9801 T14269 T14267 arg2Of antagonizes,and
R9802 T14269 T14268 arg1Of antagonizes,functionally
R9803 T14270 T14269 arg2Of p53,antagonizes
R9804 T14272 T14262 arg2Of and,appears
R9805 T14272 T14263 arg1Of and,that
R9806 T14272 T14271 arg1Of and,","
R9807 T14274 T14273 arg1Of proteins,both
R9808 T14274 T14275 arg1Of proteins,nullify
R9809 T14275 T14272 arg2Of nullify,and
R981 T1429 T1430 arg1Of al.,","
R9810 T14277 T14276 arg1Of other’s,each
R9811 T14277 T14278 arg1Of other’s,function
R9812 T14277 T14280 arg1Of other’s,inducing
R9813 T14278 T14275 arg2Of function,nullify
R9814 T14278 T14279 arg1Of function,in
R9815 T14280 T14279 arg2Of inducing,in
R9816 T14281 T14280 arg2Of apoptosis,inducing
R9817 T14286 T14284 arg1Of interactions,no
R9818 T14286 T14285 arg1Of interactions,physical
R9819 T14286 T14287 arg1Of interactions,between
R982 T1431 T1430 arg2Of 2012,","
R9820 T14286 T14293 arg1Of interactions,are
R9821 T14286 T14294 arg2Of interactions,expected
R9822 T14290 T14288 arg1Of proteins,mutant
R9823 T14290 T14289 arg1Of proteins,p53
R9824 T14290 T14291 arg1Of proteins,and
R9825 T14291 T14287 arg2Of and,between
R9826 T14292 T14291 arg2Of WWOX,and
R9827 T14294 T14282 arg1Of expected,Second
R9828 T14294 T14283 arg1Of expected,","
R9829 T14294 T14293 arg2Of expected,are
R983 T1432 T1426 arg3Of ),(
R9830 T14294 T14295 arg1Of expected,in
R9831 T14297 T14295 arg2Of cells,in
R9832 T14297 T14296 arg1Of cells,GBM
R9833 T14301 T14300 arg1Of WWOX,ectopic
R9834 T14301 T14302 arg1Of WWOX,induce
R9835 T14302 T14298 arg1Of induce,Thus
R9836 T14302 T14299 arg1Of induce,","
R9837 T14302 T14304 arg1Of induce,in
R9838 T14303 T14302 arg2Of apoptosis,induce
R9839 T14307 T14304 arg2Of cells,in
R984 T1434 T1433 arg1Of increase,An
R9840 T14307 T14305 arg1Of cells,mutant
R9841 T14307 T14306 arg1Of cells,p53-expressing
R9842 T14311 T14312 arg1Of WWOX,binds
R9843 T14312 T14310 arg1Of binds,whether
R9844 T14312 T14315 arg1Of binds,is
R9845 T14312 T14316 arg1Of binds,unknown
R9846 T14314 T14312 arg2Of isoforms,binds
R9847 T14314 T14313 arg1Of isoforms,p53
R9848 T14315 T14308 arg1Of is,Finally
R9849 T14315 T14309 arg1Of is,","
R985 T1434 T1435 arg1Of increase,in
R9850 T14316 T14315 arg2Of unknown,is
R9851 T14322 T14319 arg1Of induction,whether
R9852 T14322 T14320 arg1Of induction,ectopic
R9853 T14322 T14321 arg1Of induction,WWOX
R9854 T14322 T14323 arg1Of induction,of
R9855 T14322 T14325 arg1Of induction,in
R9856 T14322 T14331 arg1Of induction,remains
R9857 T14322 T14333 arg1Of induction,be
R9858 T14322 T14334 arg2Of induction,established
R9859 T14324 T14323 arg2Of apoptosis,of
R986 T1434 T1440 arg1Of increase,","
R9860 T14327 T14325 arg2Of cells,in
R9861 T14327 T14326 arg1Of cells,GBM
R9862 T14327 T14328 arg1Of cells,expressing
R9863 T14330 T14328 arg2Of isoforms,expressing
R9864 T14330 T14329 arg1Of isoforms,p53
R9865 T14331 T14317 arg1Of remains,Also
R9866 T14331 T14318 arg1Of remains,","
R9867 T14334 T14331 arg2Of established,remains
R9868 T14334 T14332 arg1Of established,to
R9869 T14334 T14333 arg2Of established,be
R987 T1434 T1441 arg1Of increase,which
R9870 T14335 T14336 arg1Of TAD,","
R9871 T14335 T14339 arg1Of TAD,;
R9872 T14338 T14336 arg2Of domain,","
R9873 T14338 T14337 arg1Of domain,transactivation
R9874 T14340 T14339 arg2Of PrD,;
R9875 T14340 T14341 arg1Of PrD,","
R9876 T14340 T14344 arg1Of PrD,;
R9877 T14343 T14341 arg2Of domain,","
R9878 T14343 T14342 arg1Of domain,proline
R9879 T14345 T14344 arg2Of NLS,;
R988 T1434 T1442 arg1Of increase,blocks
R9880 T14345 T14346 arg1Of NLS,","
R9881 T14345 T14350 arg1Of NLS,;
R9882 T14349 T14346 arg2Of signal,","
R9883 T14349 T14347 arg1Of signal,nuclear
R9884 T14349 T14348 arg1Of signal,localization
R9885 T14351 T14350 arg2Of OD,;
R9886 T14351 T14352 arg1Of OD,","
R9887 T14351 T14357 arg1Of OD,","
R9888 T14354 T14355 arg1Of domain,;
R9889 T14355 T14352 arg2Of ;,","
R989 T1434 T1447 arg1Of increase,prolongs
R9890 T14355 T14353 arg1Of ;,oligomerization
R9891 T14356 T14355 arg2Of BR,;
R9892 T14359 T14357 arg2Of region,","
R9893 T14359 T14358 arg1Of region,basic
R99 T233 T239 arg1Of seen,to
R990 T1439 T1435 arg2Of methylation,in
R991 T1439 T1436 arg1Of methylation,MGMT
R992 T1439 T1437 arg1Of methylation,gene
R993 T1439 T1438 arg1Of methylation,promoter
R994 T1445 T1442 arg2Of expression,blocks
R995 T1445 T1443 arg1Of expression,MGMT
R996 T1445 T1444 arg1Of expression,protein
R997 T1447 T1446 arg1Of prolongs,","
R998 T1450 T1447 arg2Of survival,prolongs
R999 T1450 T1448 arg1Of survival,cancer