Id |
Subject |
Object |
Predicate |
Lexical cue |
T260 |
0-10 |
NN |
denotes |
Deficiency |
T261 |
11-13 |
IN |
denotes |
of |
T262 |
14-17 |
NN |
denotes |
C-C |
T263 |
18-27 |
NNP |
denotes |
Chemokine |
T264 |
28-36 |
NNP |
denotes |
Receptor |
T265 |
37-38 |
CD |
denotes |
5 |
T266 |
39-49 |
VB |
denotes |
Suppresses |
T267 |
50-55 |
NN |
denotes |
Tumor |
T268 |
56-84 |
NN |
denotes |
Development via Inactivation |
T269 |
85-87 |
IN |
denotes |
of |
T270 |
88-91 |
NF- |
denotes |
NF- |
T271 |
91-92 |
NN |
denotes |
κ |
T272 |
92-95 |
CC |
denotes |
B a |
T273 |
95-107 |
NN |
denotes |
nd Upregulat |
T274 |
107-109 |
IN |
denotes |
io |
T275 |
109-115 |
NN |
denotes |
n of I |
T276 |
115-117 |
IN |
denotes |
L- |
T277 |
117-125 |
NNP |
denotes |
1Ra in M |
T278 |
125-130 |
NNP |
denotes |
elano |
T279 |
195-197 |
TO |
denotes |
To |
T280 |
198-206 |
VB |
denotes |
evaluate |
T281 |
207-210 |
DT |
denotes |
the |
T282 |
211-220 |
NN |
denotes |
relevance |
T283 |
221-223 |
IN |
denotes |
of |
T284 |
224-227 |
NN |
denotes |
C-C |
T285 |
228-237 |
NN |
denotes |
chemokine |
T286 |
238-246 |
NN |
denotes |
receptor |
T287 |
247-251 |
NN |
denotes |
type |
T288 |
252-253 |
CD |
denotes |
5 |
T289 |
254-255 |
-LRB- |
denotes |
( |
T290 |
255-259 |
NN |
denotes |
CCR5 |
T291 |
259-260 |
-RRB- |
denotes |
) |
T292 |
261-271 |
NN |
denotes |
expression |
T293 |
272-275 |
CC |
denotes |
and |
T294 |
276-281 |
NN |
denotes |
tumor |
T295 |
282-293 |
NN |
denotes |
development |
T296 |
293-294 |
-COMMA- |
denotes |
, |
T297 |
295-297 |
PRP |
denotes |
we |
T298 |
298-306 |
VB |
denotes |
compared |
T299 |
307-315 |
NN |
denotes |
melanoma |
T300 |
316-322 |
NN |
denotes |
growth |
T301 |
323-325 |
IN |
denotes |
in |
T302 |
326-330 |
NN |
denotes |
CCR5 |
T303 |
331-339 |
NN |
denotes |
knockout |
T304 |
340-341 |
-LRB- |
denotes |
( |
T305 |
341-348 |
NN |
denotes |
CCR5−/− |
T306 |
348-349 |
-RRB- |
denotes |
) |
T307 |
350-354 |
NN |
denotes |
mice |
T308 |
355-358 |
CC |
denotes |
and |
T309 |
359-363 |
JJ |
denotes |
wild |
T310 |
364-368 |
NN |
denotes |
type |
T311 |
369-370 |
-LRB- |
denotes |
( |
T312 |
370-377 |
NN |
denotes |
CCR5+/+ |
T313 |
377-378 |
-RRB- |
denotes |
) |
T314 |
379-383 |
NN |
denotes |
mice |
T315 |
385-392 |
NN |
denotes |
CCR5−/− |
T316 |
393-397 |
NN |
denotes |
mice |
T317 |
398-404 |
VB |
denotes |
showed |
T318 |
405-412 |
VB |
denotes |
reduced |
T319 |
413-418 |
NN |
denotes |
tumor |
T320 |
419-425 |
NN |
denotes |
volume |
T321 |
425-426 |
-COMMA- |
denotes |
, |
T322 |
427-432 |
NN |
denotes |
tumor |
T323 |
433-439 |
NN |
denotes |
weight |
T324 |
439-440 |
-COMMA- |
denotes |
, |
T325 |
441-444 |
CC |
denotes |
and |
T326 |
445-454 |
VB |
denotes |
increased |
T327 |
455-463 |
NN |
denotes |
survival |
T328 |
464-468 |
NN |
denotes |
rate |
T329 |
469-473 |
WRB |
denotes |
when |
T330 |
474-482 |
VB |
denotes |
compared |
T331 |
483-485 |
TO |
denotes |
to |
T332 |
486-493 |
JJ |
denotes |
CCR5+/+ |
T333 |
494-498 |
NN |
denotes |
mice |
T334 |
500-502 |
PRP |
denotes |
We |
T335 |
503-515 |
VB |
denotes |
investigated |
T336 |
516-519 |
DT |
denotes |
the |
T337 |
520-530 |
NN |
denotes |
activation |
T338 |
531-533 |
IN |
denotes |
of |
T339 |
534-539 |
NN |
denotes |
NF-κB |
T340 |
540-545 |
IN |
denotes |
since |
T341 |
546-548 |
PRP |
denotes |
it |
T342 |
549-551 |
VB |
denotes |
is |
T343 |
552-554 |
DT |
denotes |
an |
T344 |
555-565 |
VB |
denotes |
implicated |
T345 |
566-579 |
NN |
denotes |
transcription |
T346 |
580-586 |
NN |
denotes |
factor |
T347 |
587-589 |
IN |
denotes |
in |
T348 |
590-593 |
DT |
denotes |
the |
T349 |
594-604 |
NN |
denotes |
regulation |
T350 |
605-607 |
IN |
denotes |
of |
T351 |
608-613 |
NN |
denotes |
genes |
T352 |
614-623 |
VB |
denotes |
involving |
T353 |
624-628 |
NN |
denotes |
cell |
T354 |
629-635 |
NN |
denotes |
growth |
T355 |
635-636 |
-COMMA- |
denotes |
, |
T356 |
637-646 |
NN |
denotes |
apoptosis |
T357 |
646-647 |
-COMMA- |
denotes |
, |
T358 |
648-651 |
CC |
denotes |
and |
T359 |
652-657 |
NN |
denotes |
tumor |
T360 |
658-664 |
NN |
denotes |
growth |
T361 |
666-677 |
JJ |
denotes |
Significant |
T362 |
678-688 |
NN |
denotes |
inhibition |
T363 |
689-691 |
IN |
denotes |
of |
T364 |
692-695 |
NN |
denotes |
DNA |
T365 |
696-703 |
NN |
denotes |
binding |
T366 |
704-712 |
NN |
denotes |
activity |
T367 |
713-715 |
IN |
denotes |
of |
T368 |
716-721 |
NN |
denotes |
NF-κB |
T369 |
721-722 |
-COMMA- |
denotes |
, |
T370 |
723-726 |
CC |
denotes |
and |
T371 |
727-740 |
NN |
denotes |
translocation |
T372 |
741-743 |
IN |
denotes |
of |
T373 |
744-747 |
NN |
denotes |
p50 |
T374 |
748-751 |
CC |
denotes |
and |
T375 |
752-755 |
NN |
denotes |
p65 |
T376 |
756-760 |
IN |
denotes |
into |
T377 |
761-764 |
DT |
denotes |
the |
T378 |
765-772 |
NN |
denotes |
nucleus |
T379 |
773-780 |
IN |
denotes |
through |
T380 |
781-784 |
DT |
denotes |
the |
T381 |
785-795 |
NN |
denotes |
inhibition |
T382 |
796-798 |
IN |
denotes |
of |
T383 |
799-814 |
NN |
denotes |
phosphorylation |
T384 |
815-817 |
IN |
denotes |
of |
T385 |
818-821 |
NN |
denotes |
IκB |
T386 |
822-825 |
VB |
denotes |
was |
T387 |
826-831 |
VB |
denotes |
found |
T388 |
832-834 |
IN |
denotes |
in |
T389 |
835-838 |
DT |
denotes |
the |
T390 |
839-847 |
NN |
denotes |
melanoma |
T391 |
848-855 |
NN |
denotes |
tissues |
T392 |
856-858 |
IN |
denotes |
of |
T393 |
859-866 |
NN |
denotes |
CCR5−/− |
T394 |
867-871 |
NN |
denotes |
mice |
T395 |
872-880 |
VB |
denotes |
compared |
T396 |
881-883 |
TO |
denotes |
to |
T397 |
884-892 |
NN |
denotes |
melanoma |
T398 |
893-900 |
NN |
denotes |
tissues |
T399 |
901-903 |
IN |
denotes |
of |
T400 |
904-911 |
JJ |
denotes |
CCR5+/+ |
T401 |
912-916 |
NN |
denotes |
mice |
T402 |
918-923 |
NN |
denotes |
NF-κB |
T403 |
924-930 |
NN |
denotes |
target |
T404 |
931-940 |
JJ |
denotes |
apoptotic |
T405 |
941-948 |
NN |
denotes |
protein |
T406 |
949-959 |
NN |
denotes |
expression |
T407 |
959-960 |
-COMMA- |
denotes |
, |
T408 |
961-965 |
JJ |
denotes |
such |
T409 |
966-968 |
IN |
denotes |
as |
T410 |
969-976 |
VB |
denotes |
cleaved |
T411 |
977-986 |
NN |
denotes |
caspase-3 |
T412 |
986-987 |
-COMMA- |
denotes |
, |
T413 |
988-995 |
VB |
denotes |
cleaved |
T414 |
996-1000 |
NN |
denotes |
PARP |
T415 |
1000-1001 |
-COMMA- |
denotes |
, |
T416 |
1002-1005 |
CC |
denotes |
and |
T417 |
1006-1009 |
NN |
denotes |
Bax |
T418 |
1009-1010 |
-COMMA- |
denotes |
, |
T419 |
1011-1014 |
VB |
denotes |
was |
T420 |
1015-1023 |
VB |
denotes |
elevated |
T421 |
1023-1024 |
-COMMA- |
denotes |
, |
T422 |
1025-1032 |
IN |
denotes |
whereas |
T423 |
1033-1036 |
DT |
denotes |
the |
T424 |
1037-1045 |
NN |
denotes |
survival |
T425 |
1046-1053 |
NN |
denotes |
protein |
T426 |
1054-1064 |
NN |
denotes |
expression |
T427 |
1065-1071 |
NN |
denotes |
levels |
T428 |
1071-1072 |
-COMMA- |
denotes |
, |
T429 |
1073-1077 |
JJ |
denotes |
such |
T430 |
1078-1080 |
IN |
denotes |
as |
T431 |
1081-1086 |
NN |
denotes |
Bcl-2 |
T432 |
1086-1087 |
-COMMA- |
denotes |
, |
T433 |
1088-1094 |
NN |
denotes |
C-IAP1 |
T434 |
1094-1095 |
-COMMA- |
denotes |
, |
T435 |
1096-1099 |
VB |
denotes |
was |
T436 |
1100-1109 |
VB |
denotes |
decreased |
T437 |
1110-1112 |
IN |
denotes |
in |
T438 |
1113-1116 |
DT |
denotes |
the |
T439 |
1117-1125 |
NN |
denotes |
melanoma |
T440 |
1126-1133 |
NN |
denotes |
tissues |
T441 |
1134-1136 |
IN |
denotes |
of |
T442 |
1137-1144 |
NN |
denotes |
CCR5−/− |
T443 |
1145-1149 |
NN |
denotes |
mice |
T444 |
1151-1164 |
RB |
denotes |
Interestingly |
T445 |
1164-1165 |
-COMMA- |
denotes |
, |
T446 |
1166-1168 |
PRP |
denotes |
we |
T447 |
1169-1174 |
VB |
denotes |
found |
T448 |
1175-1179 |
IN |
denotes |
that |
T449 |
1180-1183 |
DT |
denotes |
the |
T450 |
1184-1189 |
NN |
denotes |
level |
T451 |
1190-1192 |
IN |
denotes |
of |
T452 |
1193-1199 |
NN |
denotes |
IL-1Ra |
T453 |
1199-1200 |
-COMMA- |
denotes |
, |
T454 |
1201-1202 |
DT |
denotes |
a |
T455 |
1203-1208 |
NN |
denotes |
tumor |
T456 |
1209-1215 |
NN |
denotes |
growth |
T457 |
1216-1227 |
JJ |
denotes |
suppressive |
T458 |
1228-1236 |
NN |
denotes |
cytokine |
T459 |
1236-1237 |
-COMMA- |
denotes |
, |
T460 |
1238-1241 |
VB |
denotes |
was |
T461 |
1242-1255 |
RB |
denotes |
significantly |
T462 |
1256-1264 |
VB |
denotes |
elevated |
T463 |
1265-1267 |
IN |
denotes |
in |
T464 |
1268-1273 |
NN |
denotes |
tumor |
T465 |
1274-1280 |
NN |
denotes |
tissue |
T466 |
1281-1284 |
CC |
denotes |
and |
T467 |
1285-1291 |
NN |
denotes |
spleen |
T468 |
1292-1294 |
IN |
denotes |
of |
T469 |
1295-1302 |
NN |
denotes |
CCR5−/− |
T470 |
1303-1307 |
NN |
denotes |
mice |
T471 |
1308-1316 |
VB |
denotes |
compared |
T472 |
1317-1319 |
TO |
denotes |
to |
T473 |
1320-1323 |
DT |
denotes |
the |
T474 |
1324-1329 |
NN |
denotes |
level |
T475 |
1330-1332 |
IN |
denotes |
in |
T476 |
1333-1340 |
JJ |
denotes |
CCR5+/+ |
T477 |
1341-1345 |
NN |
denotes |
mice |
T478 |
1347-1355 |
RB |
denotes |
Moreover |
T479 |
1355-1356 |
-COMMA- |
denotes |
, |
T480 |
1357-1369 |
NN |
denotes |
infiltration |
T481 |
1370-1372 |
IN |
denotes |
of |
T482 |
1373-1377 |
JJ |
denotes |
CD8+ |
T483 |
1378-1387 |
JJ |
denotes |
cytotoxic |
T484 |
1388-1389 |
NN |
denotes |
T |
T485 |
1390-1394 |
NN |
denotes |
cell |
T486 |
1395-1398 |
CC |
denotes |
and |
T487 |
1399-1404 |
JJ |
denotes |
CD57+ |
T488 |
1405-1412 |
JJ |
denotes |
natural |
T489 |
1413-1419 |
NN |
denotes |
killer |
T490 |
1420-1425 |
NN |
denotes |
cells |
T491 |
1426-1429 |
VB |
denotes |
was |
T492 |
1430-1443 |
RB |
denotes |
significantly |
T493 |
1444-1453 |
VB |
denotes |
increased |
T494 |
1454-1456 |
IN |
denotes |
in |
T495 |
1457-1465 |
NN |
denotes |
melanoma |
T496 |
1466-1471 |
NN |
denotes |
tumor |
T497 |
1472-1475 |
CC |
denotes |
and |
T498 |
1476-1482 |
NN |
denotes |
spleen |
T499 |
1483-1489 |
NN |
denotes |
tissue |
T500 |
1490-1492 |
IN |
denotes |
of |
T501 |
1493-1500 |
NN |
denotes |
CCR5−/− |
T502 |
1501-1505 |
NN |
denotes |
mice |
T503 |
1506-1514 |
VB |
denotes |
compared |
T504 |
1515-1517 |
TO |
denotes |
to |
T505 |
1518-1522 |
DT |
denotes |
that |
T506 |
1523-1525 |
IN |
denotes |
of |
T507 |
1526-1533 |
JJ |
denotes |
CCR5+/+ |
T508 |
1534-1538 |
NN |
denotes |
mice |
T509 |
1540-1549 |
RB |
denotes |
Therefore |
T510 |
1549-1550 |
-COMMA- |
denotes |
, |
T511 |
1551-1556 |
DT |
denotes |
these |
T512 |
1557-1564 |
NN |
denotes |
results |
T513 |
1565-1571 |
VB |
denotes |
showed |
T514 |
1572-1576 |
IN |
denotes |
that |
T515 |
1577-1581 |
NN |
denotes |
CCR5 |
T516 |
1582-1592 |
NN |
denotes |
deficiency |
T517 |
1593-1599 |
VB |
denotes |
caused |
T518 |
1600-1609 |
JJ |
denotes |
apoptotic |
T519 |
1610-1614 |
NN |
denotes |
cell |
T520 |
1615-1620 |
NN |
denotes |
death |
T521 |
1621-1623 |
IN |
denotes |
of |
T522 |
1624-1632 |
NN |
denotes |
melanoma |
T523 |
1633-1640 |
IN |
denotes |
through |
T524 |
1641-1651 |
NN |
denotes |
inhibition |
T525 |
1652-1654 |
IN |
denotes |
of |
T526 |
1655-1660 |
NN |
denotes |
NF-κB |
T527 |
1661-1664 |
CC |
denotes |
and |
T528 |
1665-1677 |
NN |
denotes |
upregulation |
T529 |
1678-1680 |
IN |
denotes |
of |
T530 |
1681-1687 |
NN |
denotes |
IL-1Ra |
T1768 |
1703-1713 |
NN |
denotes |
Chemokines |
T1769 |
1714-1717 |
VB |
denotes |
are |
T1770 |
1718-1723 |
JJ |
denotes |
small |
T1771 |
1724-1731 |
JJ |
denotes |
soluble |
T1772 |
1732-1741 |
NN |
denotes |
molecules |
T1773 |
1742-1746 |
WDT |
denotes |
that |
T1774 |
1747-1750 |
VB |
denotes |
are |
T1775 |
1751-1755 |
RB |
denotes |
best |
T1776 |
1756-1761 |
VB |
denotes |
known |
T1777 |
1762-1765 |
IN |
denotes |
for |
T1778 |
1766-1771 |
PRP-DOLLAR- |
denotes |
their |
T1779 |
1772-1778 |
JJ |
denotes |
potent |
T1780 |
1779-1786 |
NN |
denotes |
ability |
T1781 |
1787-1789 |
TO |
denotes |
to |
T1782 |
1790-1796 |
VB |
denotes |
induce |
T1783 |
1797-1803 |
NN |
denotes |
cancer |
T1784 |
1804-1808 |
NN |
denotes |
cell |
T1785 |
1809-1815 |
NN |
denotes |
growth |
T1786 |
1816-1818 |
IN |
denotes |
by |
T1787 |
1819-1831 |
NN |
denotes |
inflammation |
T1788 |
1833-1837 |
JJ |
denotes |
Many |
T1789 |
1838-1843 |
NN |
denotes |
types |
T1790 |
1844-1846 |
IN |
denotes |
of |
T1791 |
1847-1853 |
NN |
denotes |
cancer |
T1792 |
1854-1859 |
NN |
denotes |
cells |
T1793 |
1860-1867 |
VB |
denotes |
express |
T1794 |
1868-1878 |
NN |
denotes |
chemokines |
T1795 |
1879-1882 |
CC |
denotes |
and |
T1796 |
1883-1892 |
NN |
denotes |
chemokine |
T1797 |
1893-1902 |
NN |
denotes |
receptors |
T1798 |
1903-1904 |
-LRB- |
denotes |
[ |
T1799 |
1904-1905 |
CD |
denotes |
1 |
T1800 |
1905-1906 |
-RRB- |
denotes |
] |
T1801 |
1908-1911 |
DT |
denotes |
The |
T1802 |
1912-1923 |
VB |
denotes |
accumulated |
T1803 |
1924-1932 |
NN |
denotes |
evidence |
T1804 |
1933-1942 |
VB |
denotes |
indicates |
T1805 |
1943-1947 |
IN |
denotes |
that |
T1806 |
1948-1951 |
DT |
denotes |
the |
T1807 |
1952-1961 |
NN |
denotes |
chemokine |
T1808 |
1962-1963 |
-LRB- |
denotes |
( |
T1809 |
1963-1966 |
NN |
denotes |
C-C |
T1810 |
1967-1972 |
NN |
denotes |
motif |
T1811 |
1972-1973 |
-RRB- |
denotes |
) |
T1812 |
1974-1980 |
NN |
denotes |
ligand |
T1813 |
1981-1982 |
CD |
denotes |
5 |
T1814 |
1983-1984 |
-LRB- |
denotes |
( |
T1815 |
1984-1988 |
NN |
denotes |
CCL5 |
T1816 |
1988-1989 |
-RRB- |
denotes |
) |
T1817 |
1990-1993 |
CC |
denotes |
and |
T1818 |
1994-1997 |
NN |
denotes |
C-C |
T1819 |
1998-2007 |
NN |
denotes |
chemokine |
T1820 |
2008-2016 |
NN |
denotes |
receptor |
T1821 |
2017-2018 |
-LRB- |
denotes |
( |
T1822 |
2018-2022 |
NN |
denotes |
CCR5 |
T1823 |
2022-2023 |
-RRB- |
denotes |
) |
T1824 |
2023-2024 |
-COMMA- |
denotes |
, |
T1825 |
2025-2030 |
WDT |
denotes |
which |
T1826 |
2031-2034 |
VB |
denotes |
are |
T1827 |
2035-2041 |
JJ |
denotes |
potent |
T1828 |
2042-2053 |
JJ |
denotes |
chemotactic |
T1829 |
2054-2061 |
NN |
denotes |
factors |
T1830 |
2062-2065 |
IN |
denotes |
for |
T1831 |
2066-2078 |
JJ |
denotes |
inflammatory |
T1832 |
2079-2084 |
NN |
denotes |
cells |
T1833 |
2084-2085 |
-COMMA- |
denotes |
, |
T1834 |
2086-2089 |
MD |
denotes |
may |
T1835 |
2090-2092 |
VB |
denotes |
be |
T1836 |
2093-2106 |
RB |
denotes |
significantly |
T1837 |
2107-2115 |
VB |
denotes |
involved |
T1838 |
2116-2118 |
IN |
denotes |
in |
T1839 |
2119-2122 |
DT |
denotes |
the |
T1840 |
2123-2136 |
NN |
denotes |
proliferation |
T1841 |
2137-2140 |
CC |
denotes |
and |
T1842 |
2141-2151 |
NN |
denotes |
metastasis |
T1843 |
2152-2154 |
IN |
denotes |
of |
T1844 |
2155-2162 |
JJ |
denotes |
several |
T1845 |
2163-2170 |
NN |
denotes |
cancers |
T1846 |
2172-2184 |
JJ |
denotes |
Intermediate |
T1847 |
2185-2188 |
CC |
denotes |
and |
T1848 |
2189-2195 |
JJ |
denotes |
strong |
T1849 |
2196-2200 |
NN |
denotes |
CCR5 |
T1850 |
2201-2211 |
NN |
denotes |
expression |
T1851 |
2212-2214 |
VB |
denotes |
is |
T1852 |
2215-2228 |
RB |
denotes |
significantly |
T1853 |
2229-2239 |
VB |
denotes |
associated |
T1854 |
2240-2244 |
IN |
denotes |
with |
T1855 |
2245-2258 |
JJ |
denotes |
nonmetastatic |
T1856 |
2259-2270 |
NN |
denotes |
development |
T1857 |
2271-2273 |
IN |
denotes |
of |
T1858 |
2274-2284 |
JJ |
denotes |
colorectal |
T1859 |
2285-2291 |
NN |
denotes |
cancer |
T1860 |
2292-2293 |
-LRB- |
denotes |
[ |
T1861 |
2293-2294 |
CD |
denotes |
2 |
T1862 |
2294-2295 |
-RRB- |
denotes |
] |
T1863 |
2295-2296 |
-COMMA- |
denotes |
, |
T1864 |
2297-2305 |
NN |
denotes |
melanoma |
T1865 |
2306-2307 |
-LRB- |
denotes |
[ |
T1866 |
2307-2308 |
CD |
denotes |
3 |
T1867 |
2308-2309 |
-RRB- |
denotes |
] |
T1868 |
2309-2310 |
-COMMA- |
denotes |
, |
T1869 |
2311-2319 |
NN |
denotes |
hepatoma |
T1870 |
2320-2321 |
-LRB- |
denotes |
[ |
T1871 |
2321-2322 |
CD |
denotes |
4 |
T1872 |
2322-2323 |
-RRB- |
denotes |
] |
T1873 |
2323-2324 |
-COMMA- |
denotes |
, |
T1874 |
2325-2337 |
NN |
denotes |
glioblastoma |
T1875 |
2337-2338 |
-COMMA- |
denotes |
, |
T1876 |
2339-2346 |
NN |
denotes |
Hodgkin |
T1877 |
2347-2355 |
NN |
denotes |
lymphoma |
T1878 |
2356-2357 |
-LRB- |
denotes |
[ |
T1879 |
2357-2358 |
CD |
denotes |
5 |
T1880 |
2358-2359 |
-RRB- |
denotes |
] |
T1881 |
2359-2360 |
-COMMA- |
denotes |
, |
T1882 |
2361-2363 |
RB |
denotes |
as |
T1883 |
2364-2368 |
RB |
denotes |
well |
T1884 |
2369-2371 |
IN |
denotes |
as |
T1885 |
2372-2376 |
JJ |
denotes |
oral |
T1886 |
2377-2380 |
CC |
denotes |
and |
T1887 |
2381-2389 |
NN |
denotes |
prostate |
T1888 |
2390-2396 |
NN |
denotes |
cancer |
T1889 |
2397-2402 |
NN |
denotes |
cells |
T1890 |
2403-2404 |
-LRB- |
denotes |
[ |
T1891 |
2404-2405 |
CD |
denotes |
6 |
T1892 |
2405-2406 |
-RRB- |
denotes |
] |
T1893 |
2408-2413 |
JJ |
denotes |
Local |
T1894 |
2414-2424 |
NN |
denotes |
production |
T1895 |
2425-2427 |
IN |
denotes |
of |
T1896 |
2428-2431 |
DT |
denotes |
the |
T1897 |
2432-2436 |
NN |
denotes |
CCL5 |
T1898 |
2437-2439 |
VB |
denotes |
is |
T1899 |
2440-2444 |
RB |
denotes |
also |
T1900 |
2445-2454 |
JJ |
denotes |
important |
T1901 |
2455-2457 |
IN |
denotes |
in |
T1902 |
2458-2461 |
DT |
denotes |
the |
T1903 |
2462-2473 |
NN |
denotes |
progression |
T1904 |
2474-2476 |
IN |
denotes |
of |
T1905 |
2477-2483 |
NN |
denotes |
breast |
T1906 |
2484-2490 |
NN |
denotes |
cancer |
T1907 |
2491-2492 |
-LRB- |
denotes |
[ |
T1908 |
2492-2493 |
CD |
denotes |
7 |
T1909 |
2493-2494 |
-RRB- |
denotes |
] |
T1910 |
2494-2495 |
-COMMA- |
denotes |
, |
T1911 |
2496-2499 |
CC |
denotes |
and |
T1912 |
2500-2504 |
RB |
denotes |
also |
T1913 |
2505-2515 |
VB |
denotes |
correlates |
T1914 |
2516-2520 |
IN |
denotes |
with |
T1915 |
2521-2525 |
JJ |
denotes |
poor |
T1916 |
2526-2535 |
NN |
denotes |
prognosis |
T1917 |
2536-2537 |
-LRB- |
denotes |
[ |
T1918 |
2537-2538 |
CD |
denotes |
8 |
T1919 |
2538-2539 |
-RRB- |
denotes |
] |
T1920 |
2541-2550 |
RB |
denotes |
Meanwhile |
T1921 |
2550-2551 |
-COMMA- |
denotes |
, |
T1922 |
2552-2556 |
NN |
denotes |
CCR5 |
T1923 |
2557-2567 |
NN |
denotes |
disruption |
T1924 |
2568-2571 |
VB |
denotes |
has |
T1925 |
2572-2576 |
VB |
denotes |
been |
T1926 |
2577-2589 |
VB |
denotes |
demonstrated |
T1927 |
2590-2592 |
TO |
denotes |
to |
T1928 |
2593-2600 |
VB |
denotes |
inhibit |
T1929 |
2601-2613 |
JJ |
denotes |
experimental |
T1930 |
2614-2619 |
NN |
denotes |
tumor |
T1931 |
2620-2626 |
NN |
denotes |
growth |
T1932 |
2627-2630 |
CC |
denotes |
and |
T1933 |
2631-2641 |
NN |
denotes |
metastasis |
T1934 |
2642-2644 |
IN |
denotes |
of |
T1935 |
2645-2655 |
JJ |
denotes |
pancreatic |
T1936 |
2656-2662 |
NN |
denotes |
cancer |
T1937 |
2663-2664 |
-LRB- |
denotes |
[ |
T1938 |
2664-2665 |
CD |
denotes |
9 |
T1939 |
2665-2666 |
-RRB- |
denotes |
] |
T1940 |
2668-2670 |
IN |
denotes |
In |
T1941 |
2671-2679 |
NN |
denotes |
addition |
T1942 |
2679-2680 |
-COMMA- |
denotes |
, |
T1943 |
2681-2685 |
NN |
denotes |
host |
T1944 |
2686-2693 |
NN |
denotes |
absence |
T1945 |
2694-2696 |
IN |
denotes |
of |
T1946 |
2697-2701 |
NN |
denotes |
CCR5 |
T1947 |
2702-2713 |
VB |
denotes |
potentiates |
T1948 |
2714-2717 |
DT |
denotes |
the |
T1949 |
2718-2723 |
NN |
denotes |
delay |
T1950 |
2724-2726 |
IN |
denotes |
of |
T1951 |
2727-2732 |
NN |
denotes |
tumor |
T1952 |
2733-2739 |
NN |
denotes |
growth |
T1953 |
2740-2741 |
-LRB- |
denotes |
[ |
T1954 |
2741-2743 |
CD |
denotes |
10 |
T1955 |
2743-2744 |
-RRB- |
denotes |
] |
T1956 |
2744-2745 |
-COMMA- |
denotes |
, |
T1957 |
2746-2749 |
CC |
denotes |
and |
T1958 |
2750-2754 |
NN |
denotes |
CCR5 |
T1959 |
2755-2765 |
NN |
denotes |
inhibitors |
T1960 |
2766-2775 |
VB |
denotes |
prevented |
T1961 |
2776-2782 |
NN |
denotes |
cancer |
T1962 |
2783-2787 |
NN |
denotes |
cell |
T1963 |
2788-2794 |
NN |
denotes |
growth |
T1964 |
2794-2795 |
-COMMA- |
denotes |
, |
T1965 |
2796-2800 |
JJ |
denotes |
such |
T1966 |
2801-2803 |
IN |
denotes |
as |
T1967 |
2804-2812 |
NN |
denotes |
prostate |
T1968 |
2813-2819 |
NN |
denotes |
cancer |
T1969 |
2820-2821 |
-LRB- |
denotes |
[ |
T1970 |
2821-2823 |
CD |
denotes |
11 |
T1971 |
2823-2824 |
-RRB- |
denotes |
] |
T1972 |
2824-2825 |
-COMMA- |
denotes |
, |
T1973 |
2826-2832 |
NN |
denotes |
breast |
T1974 |
2833-2839 |
NN |
denotes |
cancer |
T1975 |
2839-2840 |
-COMMA- |
denotes |
, |
T1976 |
2841-2849 |
NN |
denotes |
hepatoma |
T1977 |
2850-2855 |
NN |
denotes |
cells |
T1978 |
2856-2857 |
-LRB- |
denotes |
[ |
T1979 |
2857-2858 |
CD |
denotes |
4 |
T1980 |
2858-2859 |
-RRB- |
denotes |
] |
T1981 |
2859-2860 |
-COMMA- |
denotes |
, |
T1982 |
2861-2864 |
CC |
denotes |
and |
T1983 |
2865-2869 |
NN |
denotes |
lung |
T1984 |
2870-2876 |
NN |
denotes |
cancer |
T1985 |
2877-2878 |
-LRB- |
denotes |
[ |
T1986 |
2878-2880 |
CD |
denotes |
12 |
T1987 |
2880-2881 |
-RRB- |
denotes |
] |
T1988 |
2883-2888 |
DT |
denotes |
These |
T1989 |
2889-2893 |
NN |
denotes |
data |
T1990 |
2894-2901 |
VB |
denotes |
suggest |
T1991 |
2902-2906 |
IN |
denotes |
that |
T1992 |
2907-2910 |
DT |
denotes |
the |
T1993 |
2911-2921 |
NN |
denotes |
deficiency |
T1994 |
2922-2924 |
IN |
denotes |
of |
T1995 |
2925-2937 |
JJ |
denotes |
inflammatory |
T1996 |
2938-2947 |
NN |
denotes |
chemokine |
T1997 |
2948-2956 |
NN |
denotes |
receptor |
T1998 |
2957-2961 |
NN |
denotes |
CCR5 |
T1999 |
2962-2965 |
MD |
denotes |
may |
T2000 |
2966-2974 |
VB |
denotes |
function |
T2001 |
2975-2977 |
IN |
denotes |
as |
T2002 |
2978-2979 |
DT |
denotes |
a |
T2003 |
2980-2991 |
JJ |
denotes |
suppressive |
T2004 |
2992-3000 |
NN |
denotes |
receptor |
T2005 |
3001-3003 |
IN |
denotes |
in |
T2006 |
3004-3010 |
NN |
denotes |
cancer |
T2007 |
3011-3022 |
NN |
denotes |
progression |
T2008 |
3024-3031 |
RB |
denotes |
However |
T2009 |
3031-3032 |
-COMMA- |
denotes |
, |
T2010 |
3033-3037 |
JJ |
denotes |
more |
T2011 |
3038-3045 |
NN |
denotes |
studies |
T2012 |
3046-3049 |
VB |
denotes |
are |
T2013 |
3050-3058 |
VB |
denotes |
required |
T2014 |
3059-3061 |
TO |
denotes |
to |
T2015 |
3062-3070 |
VB |
denotes |
describe |
T2016 |
3071-3074 |
WRB |
denotes |
how |
T2017 |
3075-3079 |
NN |
denotes |
CCR5 |
T2018 |
3080-3090 |
NN |
denotes |
deficiency |
T2019 |
3091-3095 |
VB |
denotes |
acts |
T2020 |
3096-3098 |
IN |
denotes |
in |
T2021 |
3099-3102 |
DT |
denotes |
the |
T2022 |
3103-3113 |
NN |
denotes |
inhibition |
T2023 |
3114-3116 |
IN |
denotes |
of |
T2024 |
3117-3122 |
NN |
denotes |
tumor |
T2025 |
3123-3134 |
NN |
denotes |
development |
T2026 |
3136-3149 |
NN |
denotes |
Interleukin-1 |
T2027 |
3150-3158 |
NN |
denotes |
receptor |
T2028 |
3159-3169 |
NN |
denotes |
antagonist |
T2029 |
3170-3171 |
-LRB- |
denotes |
( |
T2030 |
3171-3177 |
NN |
denotes |
IL-1Ra |
T2031 |
3177-3178 |
-RRB- |
denotes |
) |
T2032 |
3178-3179 |
-COMMA- |
denotes |
, |
T2033 |
3180-3181 |
DT |
denotes |
a |
T2034 |
3182-3188 |
NN |
denotes |
member |
T2035 |
3189-3191 |
IN |
denotes |
of |
T2036 |
3192-3195 |
DT |
denotes |
the |
T2037 |
3196-3200 |
NN |
denotes |
IL-1 |
T2038 |
3201-3207 |
NN |
denotes |
family |
T2039 |
3207-3208 |
-COMMA- |
denotes |
, |
T2040 |
3209-3211 |
VB |
denotes |
is |
T2041 |
3212-3213 |
DT |
denotes |
a |
T2042 |
3214-3223 |
RB |
denotes |
naturally |
T2043 |
3224-3233 |
VB |
denotes |
occurring |
T2044 |
3234-3242 |
NN |
denotes |
cytokine |
T2045 |
3243-3247 |
WDT |
denotes |
that |
T2046 |
3248-3261 |
RB |
denotes |
competitively |
T2047 |
3262-3268 |
VB |
denotes |
blocks |
T2048 |
3269-3272 |
DT |
denotes |
the |
T2049 |
3273-3277 |
NN |
denotes |
IL-1 |
T2050 |
3278-3286 |
NN |
denotes |
receptor |
T2051 |
3287-3288 |
-LRB- |
denotes |
[ |
T2052 |
3288-3290 |
CD |
denotes |
13 |
T2053 |
3290-3291 |
-RRB- |
denotes |
] |
T2054 |
3293-3300 |
IN |
denotes |
Because |
T2055 |
3301-3307 |
NN |
denotes |
IL-1Ra |
T2056 |
3308-3311 |
VB |
denotes |
has |
T2057 |
3312-3316 |
VB |
denotes |
been |
T2058 |
3317-3322 |
VB |
denotes |
shown |
T2059 |
3323-3325 |
TO |
denotes |
to |
T2060 |
3326-3333 |
VB |
denotes |
inhibit |
T2061 |
3334-3339 |
NN |
denotes |
tumor |
T2062 |
3340-3351 |
NN |
denotes |
progression |
T2063 |
3352-3354 |
IN |
denotes |
by |
T2064 |
3355-3364 |
VB |
denotes |
promoting |
T2065 |
3365-3374 |
JJ |
denotes |
antitumor |
T2066 |
3375-3381 |
JJ |
denotes |
immune |
T2067 |
3382-3391 |
NN |
denotes |
responses |
T2068 |
3392-3395 |
CC |
denotes |
and |
T2069 |
3396-3398 |
IN |
denotes |
by |
T2070 |
3399-3408 |
VB |
denotes |
enhancing |
T2071 |
3409-3412 |
DT |
denotes |
the |
T2072 |
3413-3421 |
NN |
denotes |
activity |
T2073 |
3422-3424 |
IN |
denotes |
of |
T2074 |
3425-3437 |
NN |
denotes |
chemotherapy |
T2075 |
3437-3438 |
-COMMA- |
denotes |
, |
T2076 |
3439-3447 |
JJ |
denotes |
numerous |
T2077 |
3448-3455 |
NN |
denotes |
studies |
T2078 |
3456-3460 |
VB |
denotes |
have |
T2079 |
3461-3469 |
VB |
denotes |
examined |
T2080 |
3470-3473 |
DT |
denotes |
the |
T2081 |
3474-3481 |
NN |
denotes |
ability |
T2082 |
3482-3484 |
IN |
denotes |
of |
T2083 |
3485-3491 |
NN |
denotes |
IL-1Ra |
T2084 |
3492-3494 |
TO |
denotes |
to |
T2085 |
3495-3500 |
VB |
denotes |
block |
T2086 |
3501-3506 |
NN |
denotes |
tumor |
T2087 |
3507-3518 |
NN |
denotes |
progression |
T2088 |
3520-3526 |
NN |
denotes |
IL-1Ra |
T2089 |
3527-3537 |
NN |
denotes |
expression |
T2090 |
3538-3541 |
VB |
denotes |
was |
T2091 |
3542-3549 |
VB |
denotes |
reduced |
T2092 |
3550-3552 |
IN |
denotes |
in |
T2093 |
3553-3561 |
NN |
denotes |
prostate |
T2094 |
3562-3563 |
-LRB- |
denotes |
[ |
T2095 |
3563-3565 |
CD |
denotes |
14 |
T2096 |
3565-3566 |
-RRB- |
denotes |
] |
T2097 |
3566-3567 |
-COMMA- |
denotes |
, |
T2098 |
3568-3574 |
NN |
denotes |
breast |
T2099 |
3575-3576 |
-LRB- |
denotes |
[ |
T2100 |
3576-3578 |
CD |
denotes |
15 |
T2101 |
3578-3579 |
-RRB- |
denotes |
] |
T2102 |
3579-3580 |
-COMMA- |
denotes |
, |
T2103 |
3581-3584 |
CC |
denotes |
and |
T2104 |
3585-3589 |
NN |
denotes |
skin |
T2105 |
3590-3596 |
NN |
denotes |
cancer |
T2106 |
3597-3598 |
-LRB- |
denotes |
[ |
T2107 |
3598-3600 |
CD |
denotes |
16 |
T2108 |
3600-3601 |
-RRB- |
denotes |
] |
T2109 |
3603-3605 |
PRP |
denotes |
It |
T2110 |
3606-3609 |
VB |
denotes |
was |
T2111 |
3610-3614 |
RB |
denotes |
also |
T2112 |
3615-3623 |
VB |
denotes |
reported |
T2113 |
3624-3628 |
IN |
denotes |
that |
T2114 |
3629-3639 |
JJ |
denotes |
endogenous |
T2115 |
3640-3646 |
NN |
denotes |
IL-1Ra |
T2116 |
3647-3656 |
JJ |
denotes |
deficient |
T2117 |
3657-3661 |
NN |
denotes |
mice |
T2118 |
3662-3671 |
VB |
denotes |
developed |
T2119 |
3672-3682 |
JJ |
denotes |
aggressive |
T2120 |
3683-3689 |
NN |
denotes |
tumors |
T2121 |
3690-3699 |
VB |
denotes |
following |
T2122 |
3700-3708 |
NN |
denotes |
exposure |
T2123 |
3709-3711 |
TO |
denotes |
to |
T2124 |
3712-3723 |
NN |
denotes |
carcinogens |
T2125 |
3724-3725 |
-LRB- |
denotes |
[ |
T2126 |
3725-3727 |
CD |
denotes |
17 |
T2127 |
3727-3728 |
-RRB- |
denotes |
] |
T2128 |
3730-3739 |
RB |
denotes |
Meanwhile |
T2129 |
3739-3740 |
-COMMA- |
denotes |
, |
T2130 |
3741-3754 |
NN |
denotes |
proliferation |
T2131 |
3755-3757 |
IN |
denotes |
of |
T2132 |
3758-3761 |
DT |
denotes |
the |
T2133 |
3762-3770 |
NN |
denotes |
melanoma |
T2134 |
3771-3776 |
NN |
denotes |
cells |
T2135 |
3777-3781 |
WDT |
denotes |
that |
T2136 |
3782-3786 |
VB |
denotes |
were |
T2137 |
3787-3797 |
VB |
denotes |
transduced |
T2138 |
3798-3802 |
IN |
denotes |
with |
T2139 |
3803-3809 |
NN |
denotes |
IL-1Ra |
T2140 |
3810-3814 |
NN |
denotes |
gene |
T2141 |
3815-3818 |
VB |
denotes |
was |
T2142 |
3819-3826 |
VB |
denotes |
reduced |
T2143 |
3827-3830 |
CC |
denotes |
and |
T2144 |
3831-3840 |
VB |
denotes |
inhibited |
T2145 |
3841-3849 |
NN |
denotes |
melanoma |
T2146 |
3850-3861 |
NN |
denotes |
development |
T2147 |
3862-3863 |
-LRB- |
denotes |
[ |
T2148 |
3863-3865 |
CD |
denotes |
18 |
T2149 |
3865-3866 |
-RRB- |
denotes |
] |
T2150 |
3868-3873 |
NN |
denotes |
IL-1R |
T2151 |
3874-3882 |
NN |
denotes |
blockade |
T2152 |
3883-3887 |
RB |
denotes |
also |
T2153 |
3888-3895 |
VB |
denotes |
reduced |
T2154 |
3896-3903 |
JJ |
denotes |
hepatic |
T2155 |
3904-3909 |
NN |
denotes |
tumor |
T2156 |
3910-3916 |
NN |
denotes |
growth |
T2157 |
3917-3918 |
-LRB- |
denotes |
[ |
T2158 |
3918-3920 |
CD |
denotes |
19 |
T2159 |
3920-3921 |
-RRB- |
denotes |
] |
T2160 |
3923-3931 |
RB |
denotes |
Moreover |
T2161 |
3931-3932 |
-COMMA- |
denotes |
, |
T2162 |
3933-3935 |
PRP |
denotes |
it |
T2163 |
3936-3939 |
VB |
denotes |
has |
T2164 |
3940-3944 |
RB |
denotes |
also |
T2165 |
3945-3949 |
VB |
denotes |
been |
T2166 |
3950-3958 |
VB |
denotes |
reported |
T2167 |
3959-3963 |
IN |
denotes |
that |
T2168 |
3964-3970 |
NN |
denotes |
IL-1Ra |
T2169 |
3971-3978 |
VB |
denotes |
reduces |
T2170 |
3979-3991 |
NN |
denotes |
fibrosarcoma |
T2171 |
3992-4003 |
NN |
denotes |
development |
T2172 |
4004-4005 |
-LRB- |
denotes |
[ |
T2173 |
4005-4007 |
CD |
denotes |
20 |
T2174 |
4007-4008 |
-RRB- |
denotes |
] |
T2175 |
4008-4009 |
-COMMA- |
denotes |
, |
T2176 |
4010-4013 |
NN |
denotes |
B16 |
T2177 |
4014-4022 |
NN |
denotes |
melanoma |
T2178 |
4023-4029 |
NN |
denotes |
growth |
T2179 |
4030-4033 |
CC |
denotes |
and |
T2180 |
4034-4044 |
NN |
denotes |
metastasis |
T2181 |
4045-4046 |
-LRB- |
denotes |
[ |
T2182 |
4046-4048 |
CD |
denotes |
21 |
T2183 |
4048-4049 |
-RRB- |
denotes |
] |
T2184 |
4049-4050 |
-COMMA- |
denotes |
, |
T2185 |
4051-4056 |
NN |
denotes |
colon |
T2186 |
4057-4071 |
NN |
denotes |
adenocarcinoma |
T2187 |
4072-4078 |
NN |
denotes |
growth |
T2188 |
4079-4080 |
-LRB- |
denotes |
[ |
T2189 |
4080-4082 |
CD |
denotes |
22 |
T2190 |
4082-4083 |
-RRB- |
denotes |
] |
T2191 |
4083-4084 |
-COMMA- |
denotes |
, |
T2192 |
4085-4088 |
CC |
denotes |
and |
T2193 |
4089-4093 |
NN |
denotes |
skin |
T2194 |
4094-4100 |
NN |
denotes |
cancer |
T2195 |
4101-4112 |
NN |
denotes |
development |
T2196 |
4113-4114 |
-LRB- |
denotes |
[ |
T2197 |
4114-4116 |
CD |
denotes |
23 |
T2198 |
4116-4117 |
-RRB- |
denotes |
] |
T2199 |
4119-4123 |
NN |
denotes |
IL-1 |
T2200 |
4124-4132 |
NN |
denotes |
knockout |
T2201 |
4133-4137 |
NN |
denotes |
mice |
T2202 |
4138-4146 |
VB |
denotes |
injected |
T2203 |
4147-4151 |
IN |
denotes |
with |
T2204 |
4152-4160 |
NN |
denotes |
melanoma |
T2205 |
4161-4167 |
VB |
denotes |
failed |
T2206 |
4168-4170 |
TO |
denotes |
to |
T2207 |
4171-4178 |
VB |
denotes |
develop |
T2208 |
4179-4184 |
JJ |
denotes |
solid |
T2209 |
4185-4191 |
NN |
denotes |
tumors |
T2210 |
4192-4193 |
-LRB- |
denotes |
[ |
T2211 |
4193-4195 |
CD |
denotes |
24 |
T2212 |
4195-4196 |
-RRB- |
denotes |
] |
T2213 |
4198-4200 |
PRP |
denotes |
It |
T2214 |
4201-4204 |
VB |
denotes |
was |
T2215 |
4205-4209 |
RB |
denotes |
also |
T2216 |
4210-4215 |
VB |
denotes |
found |
T2217 |
4216-4220 |
IN |
denotes |
that |
T2218 |
4221-4227 |
NN |
denotes |
IL-1Ra |
T2219 |
4227-4228 |
-COMMA- |
denotes |
, |
T2220 |
4229-4237 |
VB |
denotes |
combined |
T2221 |
4238-4242 |
IN |
denotes |
with |
T2222 |
4243-4255 |
NN |
denotes |
temozolomide |
T2223 |
4256-4259 |
CC |
denotes |
and |
T2224 |
4260-4269 |
NN |
denotes |
docetaxel |
T2225 |
4270-4282 |
NN |
denotes |
chemotherapy |
T2226 |
4282-4283 |
-COMMA- |
denotes |
, |
T2227 |
4284-4296 |
VB |
denotes |
demonstrated |
T2228 |
4297-4301 |
RB |
denotes |
more |
T2229 |
4302-4313 |
JJ |
denotes |
significant |
T2230 |
4314-4323 |
JJ |
denotes |
antitumor |
T2231 |
4324-4332 |
NN |
denotes |
activity |
T2232 |
4333-4340 |
IN |
denotes |
against |
T2233 |
4341-4344 |
NN |
denotes |
B16 |
T2234 |
4345-4353 |
NN |
denotes |
melanoma |
T2235 |
4354-4359 |
NN |
denotes |
cells |
T2236 |
4360-4362 |
FW |
denotes |
in |
T2237 |
4363-4367 |
FW |
denotes |
vivo |
T2238 |
4368-4369 |
-LRB- |
denotes |
[ |
T2239 |
4369-4371 |
CD |
denotes |
25 |
T2240 |
4371-4372 |
-RRB- |
denotes |
] |
T2241 |
4374-4379 |
DT |
denotes |
These |
T2242 |
4380-4384 |
NN |
denotes |
data |
T2243 |
4385-4393 |
VB |
denotes |
indicate |
T2244 |
4394-4398 |
IN |
denotes |
that |
T2245 |
4399-4405 |
NN |
denotes |
IL-1Ra |
T2246 |
4406-4408 |
VB |
denotes |
is |
T2247 |
4409-4418 |
JJ |
denotes |
important |
T2248 |
4419-4421 |
IN |
denotes |
as |
T2249 |
4422-4423 |
DT |
denotes |
a |
T2250 |
4424-4429 |
NN |
denotes |
tumor |
T2251 |
4430-4436 |
NN |
denotes |
growth |
T2252 |
4437-4448 |
VB |
denotes |
suppressing |
T2253 |
4449-4457 |
NN |
denotes |
cytokine |
T2254 |
4459-4464 |
NN |
denotes |
NF-κB |
T2255 |
4465-4470 |
VB |
denotes |
plays |
T2256 |
4471-4472 |
DT |
denotes |
a |
T2257 |
4473-4480 |
JJ |
denotes |
crucial |
T2258 |
4481-4485 |
NN |
denotes |
role |
T2259 |
4486-4488 |
IN |
denotes |
in |
T2260 |
4489-4492 |
DT |
denotes |
the |
T2261 |
4493-4504 |
NN |
denotes |
suppression |
T2262 |
4505-4507 |
IN |
denotes |
of |
T2263 |
4508-4517 |
NN |
denotes |
apoptosis |
T2264 |
4517-4518 |
-COMMA- |
denotes |
, |
T2265 |
4519-4521 |
RB |
denotes |
as |
T2266 |
4522-4526 |
RB |
denotes |
well |
T2267 |
4527-4529 |
IN |
denotes |
as |
T2268 |
4530-4533 |
DT |
denotes |
the |
T2269 |
4534-4543 |
NN |
denotes |
induction |
T2270 |
4544-4546 |
IN |
denotes |
of |
T2271 |
4547-4551 |
NN |
denotes |
cell |
T2272 |
4552-4565 |
NN |
denotes |
proliferation |
T2273 |
4566-4569 |
CC |
denotes |
and |
T2274 |
4570-4582 |
NN |
denotes |
inflammation |
T2275 |
4582-4583 |
-COMMA- |
denotes |
, |
T2276 |
4584-4587 |
CC |
denotes |
and |
T2277 |
4588-4590 |
VB |
denotes |
is |
T2278 |
4591-4598 |
RB |
denotes |
closely |
T2279 |
4599-4609 |
VB |
denotes |
associated |
T2280 |
4610-4614 |
IN |
denotes |
with |
T2281 |
4615-4621 |
NN |
denotes |
cancer |
T2282 |
4622-4633 |
NN |
denotes |
development |
T2283 |
4634-4635 |
-LRB- |
denotes |
[ |
T2284 |
4635-4637 |
CD |
denotes |
26 |
T2285 |
4637-4638 |
-RRB- |
denotes |
] |
T2286 |
4640-4652 |
JJ |
denotes |
Constitutive |
T2287 |
4653-4663 |
NN |
denotes |
activation |
T2288 |
4664-4666 |
IN |
denotes |
of |
T2289 |
4667-4672 |
NN |
denotes |
NF-κB |
T2290 |
4673-4676 |
VB |
denotes |
has |
T2291 |
4677-4681 |
VB |
denotes |
been |
T2292 |
4682-4691 |
VB |
denotes |
described |
T2293 |
4692-4694 |
IN |
denotes |
in |
T2294 |
4695-4696 |
DT |
denotes |
a |
T2295 |
4697-4702 |
JJ |
denotes |
great |
T2296 |
4703-4709 |
NN |
denotes |
number |
T2297 |
4710-4712 |
IN |
denotes |
of |
T2298 |
4713-4720 |
NN |
denotes |
cancers |
T2299 |
4721-4730 |
VB |
denotes |
including |
T2300 |
4731-4736 |
NN |
denotes |
colon |
T2301 |
4737-4744 |
NN |
denotes |
cancers |
T2302 |
4744-4745 |
-COMMA- |
denotes |
, |
T2303 |
4746-4754 |
NN |
denotes |
prostate |
T2304 |
4755-4762 |
NN |
denotes |
cancers |
T2305 |
4763-4766 |
CC |
denotes |
and |
T2306 |
4767-4775 |
NN |
denotes |
melanoma |
T2307 |
4776-4777 |
-LRB- |
denotes |
[ |
T2308 |
4777-4779 |
CD |
denotes |
27 |
T2309 |
4779-4780 |
-RRB- |
denotes |
] |
T2310 |
4780-4781 |
-COMMA- |
denotes |
, |
T2311 |
4782-4785 |
CC |
denotes |
and |
T2312 |
4786-4789 |
VB |
denotes |
was |
T2313 |
4790-4795 |
VB |
denotes |
found |
T2314 |
4796-4798 |
TO |
denotes |
to |
T2315 |
4799-4810 |
VB |
denotes |
up-regulate |
T2316 |
4811-4825 |
JJ |
denotes |
anti-apoptotic |
T2317 |
4826-4831 |
NN |
denotes |
genes |
T2318 |
4832-4838 |
CC |
denotes |
and/or |
T2319 |
4839-4843 |
RB |
denotes |
down |
T2320 |
4844-4852 |
VB |
denotes |
regulate |
T2321 |
4853-4862 |
JJ |
denotes |
apoptotic |
T2322 |
4863-4867 |
NN |
denotes |
gene |
T2323 |
4868-4878 |
NN |
denotes |
expression |
T2324 |
4879-4880 |
-LRB- |
denotes |
[ |
T2325 |
4880-4882 |
CD |
denotes |
28 |
T2326 |
4882-4883 |
-RRB- |
denotes |
] |
T2327 |
4885-4893 |
IN |
denotes |
Although |
T2328 |
4894-4899 |
NN |
denotes |
NF-κB |
T2329 |
4900-4908 |
VB |
denotes |
promotes |
T2330 |
4909-4914 |
NN |
denotes |
tumor |
T2331 |
4915-4921 |
NN |
denotes |
growth |
T2332 |
4921-4922 |
-COMMA- |
denotes |
, |
T2333 |
4923-4925 |
PRP |
denotes |
it |
T2334 |
4926-4928 |
VB |
denotes |
is |
T2335 |
4929-4937 |
VB |
denotes |
required |
T2336 |
4938-4941 |
IN |
denotes |
for |
T2337 |
4942-4945 |
DT |
denotes |
the |
T2338 |
4946-4952 |
JJ |
denotes |
immune |
T2339 |
4953-4959 |
NN |
denotes |
system |
T2340 |
4960-4962 |
TO |
denotes |
to |
T2341 |
4963-4971 |
VB |
denotes |
function |
T2342 |
4972-4980 |
RB |
denotes |
normally |
T2343 |
4981-4982 |
-LRB- |
denotes |
[ |
T2344 |
4982-4984 |
CD |
denotes |
29 |
T2345 |
4984-4985 |
-RRB- |
denotes |
] |
T2346 |
4987-4994 |
NN |
denotes |
Studies |
T2347 |
4995-4997 |
IN |
denotes |
on |
T2348 |
4998-5013 |
JJ |
denotes |
c-Rel-deficient |
T2349 |
5014-5018 |
NN |
denotes |
mice |
T2350 |
5019-5031 |
VB |
denotes |
demonstrated |
T2351 |
5032-5036 |
IN |
denotes |
that |
T2352 |
5037-5042 |
NN |
denotes |
c-Rel |
T2353 |
5043-5045 |
VB |
denotes |
is |
T2354 |
5046-5055 |
JJ |
denotes |
essential |
T2355 |
5056-5059 |
IN |
denotes |
for |
T2356 |
5060-5064 |
NN |
denotes |
IL-2 |
T2357 |
5064-5065 |
-COMMA- |
denotes |
, |
T2358 |
5066-5070 |
NN |
denotes |
IL-3 |
T2359 |
5070-5071 |
-COMMA- |
denotes |
, |
T2360 |
5072-5078 |
NN |
denotes |
GM-CSF |
T2361 |
5078-5079 |
-COMMA- |
denotes |
, |
T2362 |
5080-5083 |
CC |
denotes |
and |
T2363 |
5084-5088 |
NN |
denotes |
IFNγ |
T2364 |
5089-5099 |
NN |
denotes |
expression |
T2365 |
5100-5102 |
IN |
denotes |
in |
T2366 |
5103-5104 |
NN |
denotes |
T |
T2367 |
5105-5116 |
NN |
denotes |
lymphocytes |
T2368 |
5117-5118 |
-LRB- |
denotes |
[ |
T2369 |
5118-5120 |
CD |
denotes |
30 |
T2370 |
5120-5121 |
-RRB- |
denotes |
] |
T2371 |
5123-5138 |
JJ |
denotes |
C-Rel-deficient |
T2372 |
5139-5143 |
NN |
denotes |
mice |
T2373 |
5144-5148 |
RB |
denotes |
also |
T2374 |
5149-5153 |
VB |
denotes |
have |
T2375 |
5154-5155 |
DT |
denotes |
a |
T2376 |
5156-5171 |
JJ |
denotes |
tissue-specific |
T2377 |
5172-5182 |
NN |
denotes |
deficiency |
T2378 |
5183-5185 |
IN |
denotes |
of |
T2379 |
5186-5193 |
JJ |
denotes |
various |
T2380 |
5194-5203 |
NN |
denotes |
cytokines |
T2381 |
5204-5207 |
CC |
denotes |
and |
T2382 |
5208-5214 |
NN |
denotes |
growth |
T2383 |
5215-5222 |
NN |
denotes |
factors |
T2384 |
5223-5225 |
IN |
denotes |
in |
T2385 |
5226-5227 |
NN |
denotes |
T |
T2386 |
5228-5233 |
NN |
denotes |
cells |
T2387 |
5234-5237 |
CC |
denotes |
and |
T2388 |
5238-5249 |
NN |
denotes |
macrophages |
T2389 |
5250-5259 |
VB |
denotes |
affecting |
T2390 |
5260-5264 |
CC |
denotes |
both |
T2391 |
5265-5271 |
JJ |
denotes |
innate |
T2392 |
5272-5275 |
CC |
denotes |
and |
T2393 |
5276-5283 |
JJ |
denotes |
humoral |
T2394 |
5284-5290 |
JJ |
denotes |
immune |
T2395 |
5291-5300 |
NN |
denotes |
responses |
T2396 |
5301-5303 |
IN |
denotes |
in |
T2397 |
5304-5307 |
DT |
denotes |
the |
T2398 |
5308-5312 |
NN |
denotes |
host |
T2399 |
5313-5314 |
-LRB- |
denotes |
[ |
T2400 |
5314-5316 |
CD |
denotes |
31 |
T2401 |
5316-5317 |
-RRB- |
denotes |
] |
T2402 |
5319-5328 |
RB |
denotes |
Therefore |
T2403 |
5328-5329 |
-COMMA- |
denotes |
, |
T2404 |
5330-5335 |
NN |
denotes |
NF-κB |
T2405 |
5336-5339 |
MD |
denotes |
can |
T2406 |
5340-5342 |
VB |
denotes |
be |
T2407 |
5343-5352 |
RB |
denotes |
specially |
T2408 |
5353-5361 |
VB |
denotes |
targeted |
T2409 |
5362-5364 |
TO |
denotes |
to |
T2410 |
5365-5372 |
VB |
denotes |
prevent |
T2411 |
5373-5379 |
NN |
denotes |
cancer |
T2412 |
5380-5384 |
NN |
denotes |
cell |
T2413 |
5385-5391 |
NN |
denotes |
growth |
T2414 |
5392-5394 |
IN |
denotes |
by |
T2415 |
5395-5396 |
-LRB- |
denotes |
( |
T2416 |
5396-5397 |
LS |
denotes |
1 |
T2417 |
5397-5398 |
-RRB- |
denotes |
) |
T2418 |
5399-5407 |
RB |
denotes |
directly |
T2419 |
5408-5417 |
VB |
denotes |
affecting |
T2420 |
5418-5427 |
JJ |
denotes |
apoptotic |
T2421 |
5428-5434 |
NN |
denotes |
cancer |
T2422 |
5435-5439 |
NN |
denotes |
cell |
T2423 |
5440-5445 |
NN |
denotes |
death |
T2424 |
5445-5446 |
-COMMA- |
denotes |
, |
T2425 |
5447-5448 |
-LRB- |
denotes |
( |
T2426 |
5448-5449 |
CD |
denotes |
2 |
T2427 |
5449-5450 |
-RRB- |
denotes |
) |
T2428 |
5451-5462 |
VB |
denotes |
stimulating |
T2429 |
5463-5468 |
NN |
denotes |
tumor |
T2430 |
5469-5476 |
NN |
denotes |
killing |
T2431 |
5477-5488 |
NN |
denotes |
lymphocytes |
T2432 |
5489-5501 |
NN |
denotes |
infiltration |
T2433 |
5502-5504 |
CC |
denotes |
or |
T2434 |
5505-5506 |
-LRB- |
denotes |
( |
T2435 |
5506-5507 |
CD |
denotes |
3 |
T2436 |
5507-5508 |
-RRB- |
denotes |
) |
T2437 |
5509-5519 |
VB |
denotes |
increasing |
T2438 |
5520-5523 |
DT |
denotes |
the |
T2439 |
5524-5534 |
NN |
denotes |
production |
T2440 |
5535-5537 |
IN |
denotes |
of |
T2441 |
5538-5543 |
NN |
denotes |
tumor |
T2442 |
5544-5551 |
NN |
denotes |
killing |
T2443 |
5552-5563 |
NN |
denotes |
lymphokines |
T2444 |
5565-5575 |
NN |
denotes |
Activation |
T2445 |
5576-5578 |
IN |
denotes |
of |
T2446 |
5579-5584 |
NN |
denotes |
NF-κB |
T2447 |
5585-5587 |
VB |
denotes |
is |
T2448 |
5588-5597 |
JJ |
denotes |
important |
T2449 |
5598-5600 |
IN |
denotes |
in |
T2450 |
5601-5604 |
DT |
denotes |
the |
T2451 |
5605-5615 |
NN |
denotes |
regulation |
T2452 |
5616-5618 |
IN |
denotes |
of |
T2453 |
5619-5631 |
JJ |
denotes |
CCR-mediated |
T2454 |
5632-5637 |
NN |
denotes |
tumor |
T2455 |
5638-5644 |
NN |
denotes |
growth |
T2456 |
5645-5648 |
CC |
denotes |
and |
T2457 |
5649-5659 |
NN |
denotes |
metastasis |
T2458 |
5661-5663 |
PRP |
denotes |
It |
T2459 |
5664-5667 |
VB |
denotes |
was |
T2460 |
5668-5676 |
VB |
denotes |
reported |
T2461 |
5677-5681 |
IN |
denotes |
that |
T2462 |
5682-5692 |
NN |
denotes |
inhibition |
T2463 |
5693-5695 |
IN |
denotes |
of |
T2464 |
5696-5701 |
NN |
denotes |
NF-κB |
T2465 |
5702-5704 |
IN |
denotes |
by |
T2466 |
5705-5736 |
NN |
denotes |
dehydroxymethyl-epoxyquinomicin |
T2467 |
5737-5738 |
-LRB- |
denotes |
( |
T2468 |
5738-5743 |
NN |
denotes |
DHMEQ |
T2469 |
5743-5744 |
-RRB- |
denotes |
) |
T2470 |
5745-5752 |
VB |
denotes |
induces |
T2471 |
5753-5757 |
NN |
denotes |
cell |
T2472 |
5758-5763 |
NN |
denotes |
death |
T2473 |
5764-5766 |
IN |
denotes |
of |
T2474 |
5767-5774 |
JJ |
denotes |
primary |
T2475 |
5775-5783 |
NN |
denotes |
effusion |
T2476 |
5784-5792 |
NN |
denotes |
lymphoma |
T2477 |
5793-5795 |
IN |
denotes |
by |
T2478 |
5796-5806 |
NN |
denotes |
inhibition |
T2479 |
5807-5809 |
IN |
denotes |
of |
T2480 |
5810-5814 |
NN |
denotes |
CCR5 |
T2481 |
5815-5825 |
NN |
denotes |
expression |
T2482 |
5826-5827 |
-LRB- |
denotes |
[ |
T2483 |
5827-5829 |
CD |
denotes |
32 |
T2484 |
5829-5830 |
-RRB- |
denotes |
] |
T2485 |
5832-5842 |
NN |
denotes |
Activation |
T2486 |
5843-5845 |
IN |
denotes |
of |
T2487 |
5846-5851 |
NN |
denotes |
NF-κB |
T2488 |
5852-5856 |
RB |
denotes |
also |
T2489 |
5857-5866 |
VB |
denotes |
increases |
T2490 |
5867-5880 |
JJ |
denotes |
CCL5-mediated |
T2491 |
5881-5885 |
JJ |
denotes |
oral |
T2492 |
5886-5892 |
NN |
denotes |
cancer |
T2493 |
5893-5901 |
NN |
denotes |
motility |
T2494 |
5902-5903 |
-LRB- |
denotes |
( |
T2495 |
5903-5904 |
CD |
denotes |
5 |
T2496 |
5904-5905 |
-RRB- |
denotes |
) |
T2497 |
5906-5909 |
CC |
denotes |
and |
T2498 |
5910-5914 |
NN |
denotes |
lung |
T2499 |
5915-5925 |
NN |
denotes |
metastasis |
T2500 |
5926-5927 |
-LRB- |
denotes |
[ |
T2501 |
5927-5929 |
CD |
denotes |
33 |
T2502 |
5929-5930 |
-RRB- |
denotes |
] |
T2503 |
5932-5936 |
RB |
denotes |
Thus |
T2504 |
5936-5937 |
-COMMA- |
denotes |
, |
T2505 |
5938-5940 |
PRP |
denotes |
it |
T2506 |
5941-5943 |
VB |
denotes |
is |
T2507 |
5944-5952 |
JJ |
denotes |
possible |
T2508 |
5953-5957 |
IN |
denotes |
that |
T2509 |
5958-5968 |
NN |
denotes |
inhibition |
T2510 |
5969-5971 |
IN |
denotes |
of |
T2511 |
5972-5977 |
NN |
denotes |
NF-κB |
T2512 |
5978-5983 |
MD |
denotes |
could |
T2513 |
5984-5986 |
VB |
denotes |
be |
T2514 |
5987-5995 |
VB |
denotes |
involved |
T2515 |
5996-5998 |
IN |
denotes |
in |
T2516 |
5999-6003 |
NN |
denotes |
CCR5 |
T2517 |
6004-6012 |
VB |
denotes |
mediated |
T2518 |
6013-6018 |
NN |
denotes |
tumor |
T2519 |
6019-6030 |
NN |
denotes |
development |
T2520 |
6032-6037 |
NN |
denotes |
NF-κB |
T2521 |
6038-6051 |
NN |
denotes |
transcription |
T2522 |
6052-6058 |
NN |
denotes |
factor |
T2523 |
6059-6066 |
NN |
denotes |
binding |
T2524 |
6067-6072 |
NN |
denotes |
sites |
T2525 |
6073-6076 |
VB |
denotes |
are |
T2526 |
6077-6084 |
JJ |
denotes |
present |
T2527 |
6085-6087 |
IN |
denotes |
in |
T2528 |
6088-6091 |
DT |
denotes |
the |
T2529 |
6092-6100 |
NN |
denotes |
promoter |
T2530 |
6101-6107 |
NN |
denotes |
region |
T2531 |
6108-6110 |
IN |
denotes |
of |
T2532 |
6111-6126 |
JJ |
denotes |
proinflammatory |
T2533 |
6127-6135 |
NN |
denotes |
cytokine |
T2534 |
6136-6141 |
NN |
denotes |
genes |
T2535 |
6141-6142 |
-COMMA- |
denotes |
, |
T2536 |
6143-6147 |
JJ |
denotes |
such |
T2537 |
6148-6150 |
IN |
denotes |
as |
T2538 |
6151-6160 |
NN |
denotes |
IL-1alpha |
T2539 |
6160-6161 |
-COMMA- |
denotes |
, |
T2540 |
6162-6166 |
NN |
denotes |
IL-6 |
T2541 |
6166-6167 |
-COMMA- |
denotes |
, |
T2542 |
6168-6174 |
NN |
denotes |
GM-CSF |
T2543 |
6174-6175 |
-COMMA- |
denotes |
, |
T2544 |
6176-6179 |
CC |
denotes |
and |
T2545 |
6180-6182 |
NNP |
denotes |
KC |
T2546 |
6183-6184 |
-LRB- |
denotes |
[ |
T2547 |
6184-6186 |
CD |
denotes |
34 |
T2548 |
6186-6187 |
-RRB- |
denotes |
] |
T2549 |
6189-6191 |
IN |
denotes |
On |
T2550 |
6192-6195 |
DT |
denotes |
the |
T2551 |
6196-6201 |
JJ |
denotes |
other |
T2552 |
6202-6206 |
NN |
denotes |
hand |
T2553 |
6206-6207 |
-COMMA- |
denotes |
, |
T2554 |
6208-6211 |
DT |
denotes |
the |
T2555 |
6212-6218 |
NN |
denotes |
IL-1Ra |
T2556 |
6219-6221 |
VB |
denotes |
is |
T2557 |
6222-6223 |
DT |
denotes |
a |
T2558 |
6224-6232 |
JJ |
denotes |
negative |
T2559 |
6233-6242 |
NN |
denotes |
regulator |
T2560 |
6243-6245 |
IN |
denotes |
of |
T2561 |
6246-6249 |
DT |
denotes |
the |
T2562 |
6250-6262 |
JJ |
denotes |
inflammatory |
T2563 |
6263-6271 |
NN |
denotes |
response |
T2564 |
6273-6280 |
JJ |
denotes |
Several |
T2565 |
6281-6288 |
NN |
denotes |
studies |
T2566 |
6289-6293 |
VB |
denotes |
have |
T2567 |
6294-6306 |
VB |
denotes |
demonstrated |
T2568 |
6307-6310 |
DT |
denotes |
the |
T2569 |
6311-6318 |
NN |
denotes |
ability |
T2570 |
6319-6321 |
IN |
denotes |
of |
T2571 |
6322-6328 |
NN |
denotes |
IL-1Ra |
T2572 |
6329-6331 |
TO |
denotes |
to |
T2573 |
6332-6340 |
VB |
denotes |
abrogate |
T2574 |
6341-6344 |
DT |
denotes |
the |
T2575 |
6345-6360 |
JJ |
denotes |
proinflammatory |
T2576 |
6361-6368 |
NN |
denotes |
effects |
T2577 |
6369-6371 |
IN |
denotes |
of |
T2578 |
6372-6376 |
NN |
denotes |
IL-1 |
T2579 |
6378-6383 |
NNP |
denotes |
Smith |
T2580 |
6384-6386 |
FW |
denotes |
et |
T2581 |
6387-6390 |
FW |
denotes |
al. |
T2582 |
6391-6400 |
VB |
denotes |
suggested |
T2583 |
6401-6405 |
IN |
denotes |
that |
T2584 |
6406-6409 |
DT |
denotes |
the |
T2585 |
6410-6420 |
NN |
denotes |
regulation |
T2586 |
6421-6423 |
IN |
denotes |
of |
T2587 |
6424-6430 |
NN |
denotes |
IL-1Ra |
T2588 |
6431-6435 |
NN |
denotes |
gene |
T2589 |
6436-6446 |
NN |
denotes |
expression |
T2590 |
6447-6449 |
VB |
denotes |
is |
T2591 |
6450-6451 |
DT |
denotes |
a |
T2592 |
6452-6459 |
JJ |
denotes |
complex |
T2593 |
6460-6465 |
NN |
denotes |
event |
T2594 |
6466-6475 |
VB |
denotes |
involving |
T2595 |
6476-6479 |
DT |
denotes |
the |
T2596 |
6480-6492 |
NN |
denotes |
interactions |
T2597 |
6493-6495 |
IN |
denotes |
of |
T2598 |
6496-6501 |
CD |
denotes |
three |
T2599 |
6502-6511 |
JJ |
denotes |
different |
T2600 |
6512-6525 |
NN |
denotes |
transcription |
T2601 |
6526-6533 |
NN |
denotes |
factors |
T2602 |
6533-6534 |
-COLON- |
denotes |
; |
T2603 |
6535-6556 |
JJ |
denotes |
NF-κB/PU.1/GA-binding |
T2604 |
6557-6564 |
NN |
denotes |
protein |
T2605 |
6565-6572 |
NN |
denotes |
binding |
T2606 |
6573-6577 |
NN |
denotes |
site |
T2607 |
6578-6579 |
-LRB- |
denotes |
[ |
T2608 |
6579-6581 |
CD |
denotes |
35 |
T2609 |
6581-6582 |
-RRB- |
denotes |
] |
T2610 |
6584-6591 |
JJ |
denotes |
Nuclear |
T2611 |
6592-6605 |
NN |
denotes |
translocation |
T2612 |
6606-6608 |
IN |
denotes |
of |
T2613 |
6609-6614 |
NN |
denotes |
NF-κB |
T2614 |
6615-6616 |
-LRB- |
denotes |
( |
T2615 |
6616-6619 |
NN |
denotes |
p65 |
T2616 |
6619-6620 |
-RRB- |
denotes |
) |
T2617 |
6621-6624 |
VB |
denotes |
was |
T2618 |
6625-6638 |
RB |
denotes |
significantly |
T2619 |
6639-6647 |
VB |
denotes |
enhanced |
T2620 |
6648-6651 |
CC |
denotes |
and |
T2621 |
6652-6661 |
VB |
denotes |
prolonged |
T2622 |
6662-6664 |
IN |
denotes |
in |
T2623 |
6665-6681 |
JJ |
denotes |
IL-1Ra-deficient |
T2624 |
6682-6686 |
NN |
denotes |
mice |
T2625 |
6686-6687 |
-COMMA- |
denotes |
, |
T2626 |
6688-6696 |
VB |
denotes |
compared |
T2627 |
6697-6699 |
TO |
denotes |
to |
T2628 |
6700-6704 |
DT |
denotes |
that |
T2629 |
6705-6707 |
IN |
denotes |
in |
T2630 |
6708-6712 |
JJ |
denotes |
wild |
T2631 |
6713-6717 |
NN |
denotes |
type |
T2632 |
6718-6722 |
NN |
denotes |
mice |
T2633 |
6723-6724 |
-LRB- |
denotes |
[ |
T2634 |
6724-6726 |
CD |
denotes |
36 |
T2635 |
6726-6727 |
-RRB- |
denotes |
] |
T2636 |
6729-6742 |
JJ |
denotes |
Intracellular |
T2637 |
6743-6749 |
NN |
denotes |
IL-1Ra |
T2638 |
6750-6751 |
-LRB- |
denotes |
( |
T2639 |
6751-6759 |
NN |
denotes |
icIL-1Ra |
T2640 |
6759-6760 |
-RRB- |
denotes |
) |
T2641 |
6761-6764 |
VB |
denotes |
was |
T2642 |
6765-6770 |
VB |
denotes |
found |
T2643 |
6771-6773 |
TO |
denotes |
to |
T2644 |
6774-6781 |
VB |
denotes |
inhibit |
T2645 |
6782-6786 |
NN |
denotes |
IL-1 |
T2646 |
6787-6789 |
IN |
denotes |
by |
T2647 |
6790-6798 |
VB |
denotes |
blocking |
T2648 |
6799-6804 |
NN |
denotes |
NF-κB |
T2649 |
6805-6811 |
NN |
denotes |
signal |
T2650 |
6812-6824 |
NN |
denotes |
transduction |
T2651 |
6825-6833 |
NN |
denotes |
pathways |
T2652 |
6834-6836 |
IN |
denotes |
in |
T2653 |
6837-6849 |
JJ |
denotes |
inflammatory |
T2654 |
6850-6859 |
NN |
denotes |
responses |
T2655 |
6860-6861 |
-LRB- |
denotes |
[ |
T2656 |
6861-6863 |
CD |
denotes |
37 |
T2657 |
6863-6864 |
-RRB- |
denotes |
] |
T2658 |
6866-6873 |
IN |
denotes |
Because |
T2659 |
6874-6878 |
NN |
denotes |
IL-1 |
T2660 |
6879-6882 |
VB |
denotes |
has |
T2661 |
6883-6887 |
VB |
denotes |
been |
T2662 |
6888-6893 |
VB |
denotes |
shown |
T2663 |
6894-6896 |
TO |
denotes |
to |
T2664 |
6897-6899 |
VB |
denotes |
be |
T2665 |
6900-6902 |
DT |
denotes |
an |
T2666 |
6903-6910 |
NN |
denotes |
inducer |
T2667 |
6911-6913 |
IN |
denotes |
of |
T2668 |
6914-6919 |
NN |
denotes |
NF-κB |
T2669 |
6920-6930 |
NN |
denotes |
activation |
T2670 |
6931-6932 |
-LRB- |
denotes |
[ |
T2671 |
6932-6934 |
CD |
denotes |
38 |
T2672 |
6934-6935 |
-RRB- |
denotes |
] |
T2673 |
6935-6936 |
-COMMA- |
denotes |
, |
T2674 |
6937-6939 |
PRP |
denotes |
we |
T2675 |
6940-6952 |
VB |
denotes |
hypothesized |
T2676 |
6953-6957 |
IN |
denotes |
that |
T2677 |
6958-6961 |
DT |
denotes |
the |
T2678 |
6962-6972 |
NN |
denotes |
expression |
T2679 |
6973-6975 |
IN |
denotes |
of |
T2680 |
6976-6982 |
NN |
denotes |
IL-1Ra |
T2681 |
6983-6988 |
MD |
denotes |
could |
T2682 |
6989-6993 |
VB |
denotes |
play |
T2683 |
6994-6996 |
DT |
denotes |
an |
T2684 |
6997-7006 |
JJ |
denotes |
important |
T2685 |
7007-7011 |
NN |
denotes |
role |
T2686 |
7012-7014 |
IN |
denotes |
in |
T2687 |
7015-7018 |
DT |
denotes |
the |
T2688 |
7019-7028 |
JJ |
denotes |
autocrine |
T2689 |
7029-7039 |
NN |
denotes |
activation |
T2690 |
7040-7042 |
IN |
denotes |
of |
T2691 |
7043-7056 |
NN |
denotes |
transcription |
T2692 |
7057-7064 |
NN |
denotes |
factors |
T2693 |
7065-7070 |
NN |
denotes |
NF-κB |
T2694 |
7071-7073 |
CC |
denotes |
or |
T2695 |
7074-7078 |
NN |
denotes |
vice |
T2696 |
7079-7084 |
NN |
denotes |
versa |
T2697 |
7086-7090 |
RB |
denotes |
Thus |
T2698 |
7090-7091 |
-COMMA- |
denotes |
, |
T2699 |
7092-7095 |
DT |
denotes |
the |
T2700 |
7096-7099 |
NN |
denotes |
aim |
T2701 |
7100-7102 |
IN |
denotes |
of |
T2702 |
7103-7107 |
DT |
denotes |
this |
T2703 |
7108-7113 |
NN |
denotes |
study |
T2704 |
7114-7117 |
VB |
denotes |
was |
T2705 |
7118-7120 |
TO |
denotes |
to |
T2706 |
7121-7129 |
VB |
denotes |
evaluate |
T2707 |
7130-7133 |
DT |
denotes |
the |
T2708 |
7134-7139 |
NN |
denotes |
roles |
T2709 |
7140-7142 |
IN |
denotes |
of |
T2710 |
7143-7148 |
NN |
denotes |
NF-κB |
T2711 |
7149-7152 |
CC |
denotes |
and |
T2712 |
7153-7159 |
NN |
denotes |
IL-1Ra |
T2713 |
7160-7162 |
IN |
denotes |
in |
T2714 |
7163-7166 |
DT |
denotes |
the |
T2715 |
7167-7176 |
NN |
denotes |
chemokine |
T2716 |
7177-7185 |
NN |
denotes |
receptor |
T2717 |
7186-7199 |
JJ |
denotes |
CCR5-mediated |
T2718 |
7200-7211 |
NN |
denotes |
suppression |
T2719 |
7212-7214 |
IN |
denotes |
of |
T2720 |
7215-7220 |
NN |
denotes |
tumor |
T2721 |
7221-7232 |
NN |
denotes |
development |
T4601 |
7244-7254 |
NN |
denotes |
Inhibition |
T4602 |
7255-7257 |
IN |
denotes |
of |
T4603 |
7258-7263 |
NN |
denotes |
Tumor |
T4604 |
7264-7275 |
NN |
denotes |
Development |
T4605 |
7276-7278 |
IN |
denotes |
in |
T4606 |
7279-7286 |
NN |
denotes |
CCR5−/− |
T4607 |
7287-7291 |
NN |
denotes |
Mice |
T4608 |
7292-7295 |
DT |
denotes |
The |
T4609 |
7296-7302 |
NN |
denotes |
effect |
T4610 |
7303-7305 |
IN |
denotes |
of |
T4611 |
7306-7310 |
NN |
denotes |
CCR5 |
T4612 |
7311-7313 |
IN |
denotes |
in |
T4613 |
7314-7319 |
NN |
denotes |
tumor |
T4614 |
7320-7331 |
NN |
denotes |
development |
T4615 |
7332-7335 |
VB |
denotes |
was |
T4616 |
7336-7348 |
VB |
denotes |
investigated |
T4617 |
7349-7354 |
VB |
denotes |
using |
T4618 |
7355-7362 |
NN |
denotes |
CCR5+/+ |
T4619 |
7363-7366 |
CC |
denotes |
and |
T4620 |
7367-7374 |
NN |
denotes |
CCR5−/− |
T4621 |
7375-7379 |
NN |
denotes |
mice |
T4622 |
7381-7387 |
NN |
denotes |
B16-F0 |
T4623 |
7388-7396 |
NN |
denotes |
melanoma |
T4624 |
7397-7402 |
NN |
denotes |
cells |
T4625 |
7403-7407 |
VB |
denotes |
were |
T4626 |
7408-7418 |
VB |
denotes |
inoculated |
T4627 |
7419-7433 |
RB |
denotes |
subcutaneously |
T4628 |
7434-7438 |
IN |
denotes |
into |
T4629 |
7439-7446 |
NN |
denotes |
CCR5+/+ |
T4630 |
7447-7450 |
CC |
denotes |
and |
T4631 |
7451-7458 |
NN |
denotes |
CCR5−/− |
T4632 |
7459-7463 |
NN |
denotes |
mice |
T4633 |
7464-7465 |
-LRB- |
denotes |
( |
T4634 |
7465-7471 |
NN |
denotes |
n = 20 |
T4635 |
7471-7472 |
-RRB- |
denotes |
) |
T4636 |
7474-7479 |
NN |
denotes |
Tumor |
T4637 |
7480-7486 |
NN |
denotes |
growth |
T4638 |
7487-7490 |
VB |
denotes |
was |
T4639 |
7491-7500 |
VB |
denotes |
monitored |
T4640 |
7501-7504 |
IN |
denotes |
for |
T4641 |
7505-7507 |
CD |
denotes |
31 |
T4642 |
7508-7512 |
NN |
denotes |
days |
T4643 |
7514-7519 |
NN |
denotes |
Tumor |
T4644 |
7520-7526 |
NN |
denotes |
growth |
T4645 |
7527-7529 |
IN |
denotes |
in |
T4646 |
7530-7533 |
DT |
denotes |
the |
T4647 |
7534-7541 |
NN |
denotes |
CCR5−/− |
T4648 |
7542-7546 |
NN |
denotes |
mice |
T4649 |
7547-7550 |
VB |
denotes |
was |
T4650 |
7551-7564 |
RB |
denotes |
significantly |
T4651 |
7565-7570 |
JJ |
denotes |
lower |
T4652 |
7571-7575 |
IN |
denotes |
than |
T4653 |
7576-7580 |
DT |
denotes |
that |
T4654 |
7581-7583 |
IN |
denotes |
in |
T4655 |
7584-7587 |
DT |
denotes |
the |
T4656 |
7588-7595 |
JJ |
denotes |
CCR5+/+ |
T4657 |
7596-7600 |
NN |
denotes |
mice |
T4658 |
7602-7605 |
DT |
denotes |
The |
T4659 |
7606-7611 |
NN |
denotes |
tumor |
T4660 |
7612-7618 |
NN |
denotes |
growth |
T4661 |
7619-7621 |
IN |
denotes |
in |
T4662 |
7622-7625 |
DT |
denotes |
the |
T4663 |
7626-7633 |
NN |
denotes |
CCR5−/− |
T4664 |
7634-7638 |
NN |
denotes |
mice |
T4665 |
7639-7642 |
VB |
denotes |
was |
T4666 |
7643-7650 |
VB |
denotes |
reduced |
T4667 |
7651-7653 |
TO |
denotes |
to |
T4668 |
7654-7658 |
CD |
denotes |
19.1 |
T4669 |
7658-7659 |
NN |
denotes |
% |
T4670 |
7659-7660 |
-COMMA- |
denotes |
, |
T4671 |
7661-7668 |
IN |
denotes |
whereas |
T4672 |
7669-7672 |
DT |
denotes |
the |
T4673 |
7673-7678 |
NN |
denotes |
tumor |
T4674 |
7679-7685 |
NN |
denotes |
growth |
T4675 |
7686-7688 |
IN |
denotes |
in |
T4676 |
7689-7692 |
DT |
denotes |
the |
T4677 |
7693-7700 |
JJ |
denotes |
CCR5+/+ |
T4678 |
7701-7705 |
NN |
denotes |
mice |
T4679 |
7706-7709 |
VB |
denotes |
was |
T4680 |
7710-7714 |
RB |
denotes |
only |
T4681 |
7715-7722 |
VB |
denotes |
reduced |
T4682 |
7723-7725 |
TO |
denotes |
to |
T4683 |
7726-7730 |
CD |
denotes |
24.3 |
T4684 |
7730-7731 |
NN |
denotes |
% |
T4685 |
7731-7732 |
-COMMA- |
denotes |
, |
T4686 |
7733-7735 |
IN |
denotes |
in |
T4687 |
7736-7740 |
CC |
denotes |
both |
T4688 |
7741-7746 |
NN |
denotes |
tumor |
T4689 |
7747-7753 |
NN |
denotes |
weight |
T4690 |
7754-7755 |
-LRB- |
denotes |
( |
T4691 |
7755-7761 |
NN |
denotes |
Figure |
T4692 |
7762-7764 |
NN |
denotes |
1A |
T4693 |
7765-7768 |
CC |
denotes |
and |
T4694 |
7769-7771 |
NN |
denotes |
1B |
T4695 |
7771-7772 |
-RRB- |
denotes |
) |
T4696 |
7773-7776 |
CC |
denotes |
and |
T4697 |
7777-7782 |
NN |
denotes |
tumor |
T4698 |
7783-7789 |
NN |
denotes |
volume |
T4699 |
7789-7790 |
-COMMA- |
denotes |
, |
T4700 |
7791-7803 |
RB |
denotes |
respectively |
T4701 |
7804-7805 |
-LRB- |
denotes |
( |
T4702 |
7805-7811 |
NN |
denotes |
Figure |
T4703 |
7812-7814 |
NN |
denotes |
1A |
T4704 |
7815-7818 |
CC |
denotes |
and |
T4705 |
7819-7821 |
NN |
denotes |
1C |
T4706 |
7821-7822 |
-RRB- |
denotes |
) |
T4707 |
7824-7829 |
DT |
denotes |
These |
T4708 |
7830-7837 |
NN |
denotes |
results |
T4709 |
7838-7848 |
VB |
denotes |
correlated |
T4710 |
7849-7853 |
IN |
denotes |
with |
T4711 |
7854-7858 |
NN |
denotes |
mice |
T4712 |
7859-7867 |
NN |
denotes |
survival |
T4713 |
7868-7873 |
NN |
denotes |
rates |
T4714 |
7875-7880 |
EX |
denotes |
There |
T4715 |
7881-7884 |
VB |
denotes |
was |
T4716 |
7885-7886 |
DT |
denotes |
a |
T4717 |
7887-7898 |
JJ |
denotes |
significant |
T4718 |
7899-7909 |
NN |
denotes |
difference |
T4719 |
7910-7912 |
IN |
denotes |
in |
T4720 |
7913-7921 |
NN |
denotes |
survival |
T4721 |
7922-7927 |
NN |
denotes |
rates |
T4722 |
7928-7935 |
IN |
denotes |
between |
T4723 |
7936-7943 |
NN |
denotes |
CCR5−/− |
T4724 |
7944-7948 |
NN |
denotes |
mice |
T4725 |
7949-7950 |
-LRB- |
denotes |
( |
T4726 |
7950-7952 |
CD |
denotes |
75 |
T4727 |
7952-7953 |
NN |
denotes |
% |
T4728 |
7954-7956 |
IN |
denotes |
of |
T4729 |
7957-7965 |
VB |
denotes |
starting |
T4730 |
7966-7970 |
NN |
denotes |
time |
T4731 |
7970-7971 |
-RRB- |
denotes |
) |
T4732 |
7972-7975 |
CC |
denotes |
and |
T4733 |
7976-7983 |
JJ |
denotes |
CCR5+/+ |
T4734 |
7984-7988 |
NN |
denotes |
mice |
T4735 |
7989-7990 |
-LRB- |
denotes |
( |
T4736 |
7990-7992 |
CD |
denotes |
15 |
T4737 |
7992-7993 |
NN |
denotes |
% |
T4738 |
7993-7994 |
-RRB- |
denotes |
) |
T4739 |
7995-7997 |
IN |
denotes |
at |
T4740 |
7998-8001 |
DT |
denotes |
the |
T4741 |
8002-8005 |
NN |
denotes |
end |
T4742 |
8006-8008 |
IN |
denotes |
of |
T4743 |
8009-8012 |
DT |
denotes |
the |
T4744 |
8013-8023 |
NN |
denotes |
experiment |
T4745 |
8024-8025 |
-LRB- |
denotes |
( |
T4746 |
8025-8031 |
NN |
denotes |
Figure |
T4747 |
8032-8034 |
NN |
denotes |
1D |
T4748 |
8034-8035 |
-RRB- |
denotes |
) |
T4749 |
8037-8042 |
EX |
denotes |
There |
T4750 |
8043-8046 |
VB |
denotes |
was |
T4751 |
8047-8048 |
DT |
denotes |
a |
T4752 |
8049-8060 |
JJ |
denotes |
significant |
T4753 |
8061-8071 |
NN |
denotes |
difference |
T4754 |
8072-8074 |
IN |
denotes |
in |
T4755 |
8075-8083 |
NN |
denotes |
survival |
T4756 |
8084-8089 |
NN |
denotes |
rates |
T4757 |
8090-8097 |
IN |
denotes |
between |
T4758 |
8098-8105 |
NN |
denotes |
CCR5−/− |
T4759 |
8106-8110 |
NN |
denotes |
mice |
T4760 |
8111-8114 |
CC |
denotes |
and |
T4761 |
8115-8122 |
JJ |
denotes |
CCR5+/+ |
T4762 |
8123-8127 |
NN |
denotes |
mice |
T4763 |
8129-8131 |
IN |
denotes |
At |
T4764 |
8132-8135 |
DT |
denotes |
the |
T4765 |
8136-8139 |
NN |
denotes |
end |
T4766 |
8140-8142 |
IN |
denotes |
of |
T4767 |
8143-8146 |
DT |
denotes |
the |
T4768 |
8147-8157 |
NN |
denotes |
experiment |
T4769 |
8157-8158 |
-COMMA- |
denotes |
, |
T4770 |
8159-8161 |
CD |
denotes |
75 |
T4771 |
8161-8162 |
NN |
denotes |
% |
T4772 |
8163-8165 |
IN |
denotes |
of |
T4773 |
8166-8169 |
DT |
denotes |
the |
T4774 |
8170-8177 |
NN |
denotes |
CCR5−/− |
T4775 |
8178-8182 |
NN |
denotes |
mice |
T4776 |
8183-8191 |
VB |
denotes |
survived |
T4777 |
8192-8197 |
IN |
denotes |
while |
T4778 |
8198-8202 |
RB |
denotes |
only |
T4779 |
8203-8205 |
CD |
denotes |
15 |
T4780 |
8205-8206 |
NN |
denotes |
% |
T4781 |
8207-8209 |
IN |
denotes |
of |
T4782 |
8210-8213 |
DT |
denotes |
the |
T4783 |
8214-8221 |
JJ |
denotes |
CCR5+/+ |
T4784 |
8222-8226 |
NN |
denotes |
mice |
T4785 |
8227-8235 |
VB |
denotes |
survived |
T4786 |
8237-8249 |
JJ |
denotes |
Subcutaneous |
T4787 |
8250-8256 |
NN |
denotes |
tumors |
T4788 |
8257-8261 |
VB |
denotes |
were |
T4789 |
8262-8271 |
VB |
denotes |
harvested |
T4790 |
8272-8276 |
IN |
denotes |
from |
T4791 |
8277-8280 |
DT |
denotes |
the |
T4792 |
8281-8291 |
VB |
denotes |
sacrificed |
T4793 |
8292-8296 |
NN |
denotes |
mice |
T4794 |
8297-8299 |
CD |
denotes |
31 |
T4795 |
8300-8304 |
NN |
denotes |
days |
T4796 |
8305-8310 |
IN |
denotes |
after |
T4797 |
8311-8322 |
NN |
denotes |
inoculation |
T4798 |
8324-8327 |
DT |
denotes |
The |
T4799 |
8328-8347 |
JJ |
denotes |
immunohistochemical |
T4800 |
8348-8356 |
NN |
denotes |
analysis |
T4801 |
8357-8359 |
IN |
denotes |
of |
T4802 |
8360-8365 |
NN |
denotes |
tumor |
T4803 |
8366-8374 |
NN |
denotes |
sections |
T4804 |
8374-8375 |
-COMMA- |
denotes |
, |
T4805 |
8376-8383 |
VB |
denotes |
stained |
T4806 |
8384-8388 |
IN |
denotes |
with |
T4807 |
8389-8390 |
NN |
denotes |
H |
T4808 |
8390-8391 |
CC |
denotes |
& |
T4809 |
8391-8392 |
NN |
denotes |
E |
T4810 |
8393-8396 |
CC |
denotes |
and |
T4811 |
8397-8400 |
IN |
denotes |
for |
T4812 |
8401-8414 |
NN |
denotes |
proliferation |
T4813 |
8415-8422 |
NN |
denotes |
antigen |
T4814 |
8423-8427 |
NN |
denotes |
PCNA |
T4815 |
8427-8428 |
-COMMA- |
denotes |
, |
T4816 |
8429-8437 |
VB |
denotes |
revealed |
T4817 |
8438-8445 |
JJ |
denotes |
greater |
T4818 |
8446-8456 |
NN |
denotes |
inhibition |
T4819 |
8457-8459 |
IN |
denotes |
of |
T4820 |
8460-8465 |
NN |
denotes |
tumor |
T4821 |
8466-8470 |
NN |
denotes |
cell |
T4822 |
8471-8477 |
NN |
denotes |
growth |
T4823 |
8478-8480 |
IN |
denotes |
in |
T4824 |
8481-8488 |
NN |
denotes |
CCR5−/− |
T4825 |
8489-8493 |
NN |
denotes |
mice |
T4826 |
8495-8498 |
DT |
denotes |
The |
T4827 |
8499-8509 |
JJ |
denotes |
histologic |
T4828 |
8510-8518 |
NN |
denotes |
findings |
T4829 |
8519-8524 |
IN |
denotes |
after |
T4830 |
8525-8526 |
NN |
denotes |
H |
T4831 |
8526-8527 |
CC |
denotes |
& |
T4832 |
8527-8528 |
NN |
denotes |
E |
T4833 |
8529-8537 |
NN |
denotes |
staining |
T4834 |
8538-8547 |
VB |
denotes |
indicated |
T4835 |
8548-8552 |
IN |
denotes |
that |
T4836 |
8553-8556 |
DT |
denotes |
the |
T4837 |
8557-8562 |
NN |
denotes |
tumor |
T4838 |
8563-8570 |
NN |
denotes |
tissues |
T4839 |
8571-8573 |
IN |
denotes |
of |
T4840 |
8574-8577 |
DT |
denotes |
the |
T4841 |
8578-8585 |
NN |
denotes |
CCR5−/− |
T4842 |
8586-8590 |
NN |
denotes |
mice |
T4843 |
8590-8591 |
-COMMA- |
denotes |
, |
T4844 |
8592-8595 |
CC |
denotes |
but |
T4845 |
8596-8599 |
RB |
denotes |
not |
T4846 |
8600-8605 |
DT |
denotes |
those |
T4847 |
8606-8608 |
IN |
denotes |
of |
T4848 |
8609-8612 |
DT |
denotes |
the |
T4849 |
8613-8620 |
JJ |
denotes |
CCR5+/+ |
T4850 |
8621-8625 |
NN |
denotes |
mice |
T4851 |
8625-8626 |
-COMMA- |
denotes |
, |
T4852 |
8627-8636 |
VB |
denotes |
contained |
T4853 |
8637-8642 |
JJ |
denotes |
large |
T4854 |
8643-8648 |
NN |
denotes |
areas |
T4855 |
8649-8651 |
IN |
denotes |
of |
T4856 |
8652-8660 |
NN |
denotes |
necrosis |
T4857 |
8662-8666 |
NN |
denotes |
PCNA |
T4858 |
8667-8675 |
JJ |
denotes |
reactive |
T4859 |
8676-8681 |
NN |
denotes |
cells |
T4860 |
8682-8686 |
VB |
denotes |
were |
T4861 |
8687-8700 |
RB |
denotes |
significantly |
T4862 |
8701-8708 |
VB |
denotes |
reduced |
T4863 |
8709-8711 |
IN |
denotes |
in |
T4864 |
8712-8715 |
DT |
denotes |
the |
T4865 |
8716-8723 |
NN |
denotes |
CCR5−/− |
T4866 |
8724-8728 |
NN |
denotes |
mice |
T4867 |
8729-8730 |
-LRB- |
denotes |
( |
T4868 |
8730-8736 |
NN |
denotes |
Figure |
T4869 |
8737-8739 |
NN |
denotes |
1E |
T4870 |
8739-8740 |
-RRB- |
denotes |
) |
T17257 |
8786-8796 |
NN |
denotes |
Inhibition |
T17258 |
8797-8799 |
IN |
denotes |
of |
T17259 |
8800-8805 |
NN |
denotes |
tumor |
T17260 |
8806-8817 |
NN |
denotes |
development |
T17261 |
8818-8820 |
IN |
denotes |
in |
T17262 |
8821-8828 |
NN |
denotes |
CCR5−/− |
T17263 |
8829-8833 |
NN |
denotes |
mice |
T17264 |
8835-8838 |
NN |
denotes |
A–C |
T17265 |
8838-8839 |
-COMMA- |
denotes |
, |
T17266 |
8840-8845 |
NN |
denotes |
Tumor |
T17267 |
8846-8852 |
NN |
denotes |
images |
T17268 |
8852-8853 |
-COMMA- |
denotes |
, |
T17269 |
8854-8861 |
NN |
denotes |
volumes |
T17270 |
8861-8862 |
-COMMA- |
denotes |
, |
T17271 |
8863-8866 |
CC |
denotes |
and |
T17272 |
8867-8874 |
NN |
denotes |
weights |
T17273 |
8876-8879 |
NN |
denotes |
B16 |
T17274 |
8880-8888 |
NN |
denotes |
melanoma |
T17275 |
8889-8894 |
NN |
denotes |
cells |
T17276 |
8895-8896 |
-LRB- |
denotes |
( |
T17277 |
8896-8901 |
CD |
denotes |
5×105 |
T17278 |
8902-8913 |
NN |
denotes |
cells/mouse |
T17279 |
8913-8914 |
-RRB- |
denotes |
) |
T17280 |
8915-8919 |
VB |
denotes |
were |
T17281 |
8920-8930 |
VB |
denotes |
inoculated |
T17282 |
8931-8935 |
RB |
denotes |
s.c. |
T17283 |
8936-8940 |
IN |
denotes |
into |
T17284 |
8941-8948 |
JJ |
denotes |
CCR5+/+ |
T17285 |
8949-8953 |
NN |
denotes |
mice |
T17286 |
8954-8957 |
CC |
denotes |
and |
T17287 |
8958-8965 |
NN |
denotes |
CCR5−/− |
T17288 |
8966-8970 |
NN |
denotes |
mice |
T17289 |
8971-8972 |
-LRB- |
denotes |
( |
T17290 |
8972-8978 |
NN |
denotes |
n = 20 |
T17291 |
8978-8979 |
-RRB- |
denotes |
) |
T17292 |
8981-8986 |
NN |
denotes |
Tumor |
T17293 |
8987-8994 |
NN |
denotes |
volumes |
T17294 |
8995-8999 |
VB |
denotes |
were |
T17295 |
9000-9008 |
VB |
denotes |
measured |
T17296 |
9009-9014 |
DT |
denotes |
every |
T17297 |
9015-9018 |
NN |
denotes |
day |
T17298 |
9019-9022 |
CC |
denotes |
and |
T17299 |
9023-9028 |
NN |
denotes |
tumor |
T17300 |
9029-9036 |
NN |
denotes |
weights |
T17301 |
9037-9041 |
VB |
denotes |
were |
T17302 |
9042-9050 |
VB |
denotes |
measured |
T17303 |
9051-9053 |
IN |
denotes |
at |
T17304 |
9054-9059 |
NN |
denotes |
study |
T17305 |
9060-9071 |
NN |
denotes |
termination |
T17306 |
9072-9073 |
-LRB- |
denotes |
( |
T17307 |
9073-9076 |
NN |
denotes |
Day |
T17308 |
9077-9079 |
CD |
denotes |
31 |
T17309 |
9079-9080 |
-RRB- |
denotes |
) |
T17310 |
9082-9085 |
DT |
denotes |
The |
T17311 |
9086-9093 |
NN |
denotes |
CCR5−/− |
T17312 |
9094-9098 |
NN |
denotes |
mice |
T17313 |
9099-9102 |
VB |
denotes |
had |
T17314 |
9103-9104 |
DT |
denotes |
a |
T17315 |
9105-9116 |
JJ |
denotes |
significant |
T17316 |
9117-9126 |
NN |
denotes |
reduction |
T17317 |
9127-9129 |
IN |
denotes |
in |
T17318 |
9130-9135 |
NN |
denotes |
tumor |
T17319 |
9136-9142 |
NN |
denotes |
growth |
T17320 |
9143-9146 |
CC |
denotes |
and |
T17321 |
9147-9153 |
NN |
denotes |
volume |
T17322 |
9154-9156 |
IN |
denotes |
as |
T17323 |
9157-9165 |
VB |
denotes |
compared |
T17324 |
9166-9168 |
TO |
denotes |
to |
T17325 |
9169-9176 |
JJ |
denotes |
CCR5+/+ |
T17326 |
9177-9181 |
NN |
denotes |
mice |
T17327 |
9183-9186 |
DT |
denotes |
The |
T17328 |
9187-9194 |
NN |
denotes |
results |
T17329 |
9195-9198 |
VB |
denotes |
are |
T17330 |
9199-9208 |
VB |
denotes |
expressed |
T17331 |
9209-9211 |
IN |
denotes |
as |
T17332 |
9212-9216 |
JJ |
denotes |
mean |
T17333 |
9217-9218 |
SYM |
denotes |
± |
T17334 |
9219-9222 |
NNP |
denotes |
SD. |
T17335 |
9223-9224 |
SYM |
denotes |
* |
T17336 |
9225-9234 |
VB |
denotes |
indicates |
T17337 |
9235-9246 |
JJ |
denotes |
significant |
T17338 |
9247-9257 |
NN |
denotes |
difference |
T17339 |
9258-9262 |
IN |
denotes |
from |
T17340 |
9263-9270 |
JJ |
denotes |
CCR5+/+ |
T17341 |
9271-9275 |
NN |
denotes |
mice |
T17342 |
9276-9277 |
-LRB- |
denotes |
( |
T17343 |
9277-9278 |
NN |
denotes |
P |
T17344 |
9278-9279 |
SYM |
denotes |
< |
T17345 |
9279-9283 |
CD |
denotes |
0.05 |
T17346 |
9283-9284 |
-RRB- |
denotes |
) |
T17347 |
9286-9287 |
NN |
denotes |
D |
T17348 |
9287-9288 |
-COMMA- |
denotes |
, |
T17349 |
9289-9292 |
DT |
denotes |
The |
T17350 |
9293-9300 |
NN |
denotes |
CCR5−/− |
T17351 |
9301-9305 |
NN |
denotes |
mice |
T17352 |
9306-9318 |
VB |
denotes |
demonstrated |
T17353 |
9319-9332 |
RB |
denotes |
significantly |
T17354 |
9333-9339 |
JJ |
denotes |
higher |
T17355 |
9340-9348 |
NN |
denotes |
survival |
T17356 |
9349-9354 |
NN |
denotes |
rates |
T17357 |
9355-9363 |
VB |
denotes |
compared |
T17358 |
9364-9366 |
TO |
denotes |
to |
T17359 |
9367-9374 |
JJ |
denotes |
CCR5+/+ |
T17360 |
9375-9379 |
NN |
denotes |
mice |
T17361 |
9380-9381 |
-LRB- |
denotes |
( |
T17362 |
9381-9383 |
IN |
denotes |
by |
T17363 |
9384-9392 |
NNP |
denotes |
Log-rank |
T17364 |
9393-9397 |
NNP |
denotes |
Test |
T17365 |
9397-9398 |
-RRB- |
denotes |
) |
T17366 |
9400-9402 |
FW |
denotes |
E. |
T17367 |
9403-9408 |
NN |
denotes |
Tumor |
T17368 |
9409-9417 |
NN |
denotes |
sections |
T17369 |
9418-9422 |
VB |
denotes |
were |
T17370 |
9423-9431 |
VB |
denotes |
analyzed |
T17371 |
9432-9434 |
IN |
denotes |
by |
T17372 |
9435-9436 |
NN |
denotes |
H |
T17373 |
9436-9437 |
CC |
denotes |
& |
T17374 |
9437-9438 |
NN |
denotes |
E |
T17375 |
9439-9444 |
NN |
denotes |
stain |
T17376 |
9445-9448 |
CC |
denotes |
and |
T17377 |
9449-9459 |
NN |
denotes |
expression |
T17378 |
9460-9462 |
IN |
denotes |
of |
T17379 |
9463-9476 |
VB |
denotes |
proliferating |
T17380 |
9477-9481 |
NN |
denotes |
cell |
T17381 |
9482-9489 |
JJ |
denotes |
nuclear |
T17382 |
9490-9497 |
NN |
denotes |
antigen |
T17383 |
9498-9499 |
-LRB- |
denotes |
( |
T17384 |
9499-9503 |
NN |
denotes |
PCNA |
T17385 |
9503-9504 |
-RRB- |
denotes |
) |
T17386 |
9505-9507 |
IN |
denotes |
by |
T17387 |
9508-9528 |
NN |
denotes |
immunohistochemistry |
T17388 |
9530-9534 |
NN |
denotes |
Data |
T17389 |
9535-9538 |
VB |
denotes |
are |
T17390 |
9539-9544 |
NN |
denotes |
means |
T17391 |
9545-9546 |
VB |
denotes |
± |
T17392 |
9547-9551 |
NNP |
denotes |
S.D. |
T17393 |
9552-9554 |
IN |
denotes |
of |
T17394 |
9555-9559 |
CD |
denotes |
four |
T17395 |
9560-9572 |
JJ |
denotes |
experimental |
T17396 |
9573-9581 |
NN |
denotes |
animals. |
T17397 |
9582-9583 |
SYM |
denotes |
* |
T17398 |
9584-9593 |
VB |
denotes |
indicates |
T17399 |
9594-9605 |
JJ |
denotes |
significant |
T17400 |
9606-9616 |
NN |
denotes |
difference |
T17401 |
9617-9621 |
IN |
denotes |
from |
T17402 |
9622-9629 |
JJ |
denotes |
CCR5+/+ |
T17403 |
9630-9634 |
NN |
denotes |
mice |
T17404 |
9635-9636 |
-LRB- |
denotes |
( |
T17405 |
9636-9637 |
NN |
denotes |
P |
T17406 |
9637-9638 |
SYM |
denotes |
< |
T17407 |
9638-9642 |
CD |
denotes |
0.05 |
T17408 |
9642-9643 |
-RRB- |
denotes |
) |
T17409 |
9645-9650 |
NN |
denotes |
Scale |
T17410 |
9651-9654 |
NN |
denotes |
bar |
T17411 |
9655-9664 |
VB |
denotes |
indicates |
T17412 |
9665-9667 |
CD |
denotes |
50 |
T17413 |
9668-9669 |
NN |
denotes |
m |
T17786 |
9672-9680 |
NN |
denotes |
Decrease |
T5481 |
9672-9680 |
NN |
denotes |
Decrease |
T17787 |
9681-9683 |
IN |
denotes |
of |
T5482 |
9681-9683 |
IN |
denotes |
of |
T17788 |
9684-9689 |
NN |
denotes |
NF-κB |
T5483 |
9684-9689 |
NN |
denotes |
NF-κB |
T17789 |
9690-9698 |
NN |
denotes |
Activity |
T5484 |
9690-9698 |
NN |
denotes |
Activity |
T17790 |
9699-9701 |
IN |
denotes |
in |
T5485 |
9699-9701 |
IN |
denotes |
in |
T17791 |
9702-9707 |
NN |
denotes |
Tumor |
T5486 |
9702-9707 |
NN |
denotes |
Tumor |
T17792 |
9708-9714 |
NN |
denotes |
Tissue |
T5487 |
9708-9714 |
NN |
denotes |
Tissue |
T17793 |
9715-9717 |
IN |
denotes |
of |
T5488 |
9715-9717 |
IN |
denotes |
of |
T17794 |
9718-9725 |
NN |
denotes |
CCR5−/− |
T5489 |
9718-9725 |
NN |
denotes |
CCR5−/− |
T17795 |
9726-9730 |
NN |
denotes |
Mice |
T5490 |
9726-9730 |
NN |
denotes |
Mice |
T5491 |
9731-9734 |
DT |
denotes |
The |
T5492 |
9735-9745 |
NN |
denotes |
activation |
T5493 |
9746-9748 |
IN |
denotes |
of |
T5494 |
9749-9754 |
NN |
denotes |
NF-κB |
T5495 |
9755-9760 |
VB |
denotes |
plays |
T5496 |
9761-9762 |
DT |
denotes |
a |
T5497 |
9763-9771 |
JJ |
denotes |
critical |
T5498 |
9772-9776 |
NN |
denotes |
role |
T5499 |
9777-9779 |
IN |
denotes |
in |
T5500 |
9780-9786 |
NN |
denotes |
cancer |
T5501 |
9787-9791 |
NN |
denotes |
cell |
T5502 |
9792-9800 |
NN |
denotes |
survival |
T5503 |
9800-9801 |
-COMMA- |
denotes |
, |
T5504 |
9802-9812 |
RB |
denotes |
especially |
T5505 |
9813-9821 |
NN |
denotes |
melanoma |
T5506 |
9822-9828 |
NN |
denotes |
cancer |
T5507 |
9829-9834 |
NN |
denotes |
cells |
T5508 |
9835-9838 |
CC |
denotes |
and |
T5509 |
9839-9841 |
IN |
denotes |
in |
T5510 |
9842-9846 |
NN |
denotes |
CCR5 |
T5511 |
9847-9857 |
NN |
denotes |
expression |
T5512 |
9859-9861 |
TO |
denotes |
To |
T5513 |
9862-9870 |
VB |
denotes |
evaluate |
T5514 |
9871-9878 |
IN |
denotes |
whether |
T5515 |
9879-9882 |
DT |
denotes |
the |
T5516 |
9883-9888 |
NN |
denotes |
tumor |
T5517 |
9889-9899 |
NN |
denotes |
inhibition |
T5518 |
9900-9903 |
VB |
denotes |
was |
T5519 |
9904-9911 |
VB |
denotes |
related |
T5520 |
9912-9916 |
IN |
denotes |
with |
T5521 |
9917-9920 |
DT |
denotes |
the |
T5522 |
9921-9933 |
NN |
denotes |
inactivation |
T5523 |
9934-9936 |
IN |
denotes |
of |
T5524 |
9937-9942 |
NN |
denotes |
NF-κB |
T5525 |
9943-9945 |
IN |
denotes |
in |
T5526 |
9946-9954 |
NN |
denotes |
melanoma |
T5527 |
9954-9955 |
-COMMA- |
denotes |
, |
T5528 |
9956-9959 |
DT |
denotes |
the |
T5529 |
9960-9963 |
NN |
denotes |
DNA |
T5530 |
9964-9971 |
NN |
denotes |
binding |
T5531 |
9972-9980 |
NN |
denotes |
activity |
T5532 |
9981-9983 |
IN |
denotes |
of |
T5533 |
9984-9989 |
NN |
denotes |
NF-κB |
T5534 |
9990-9993 |
VB |
denotes |
was |
T5535 |
9994-10004 |
VB |
denotes |
determined |
T5536 |
10005-10007 |
IN |
denotes |
by |
T5537 |
10008-10023 |
NN |
denotes |
electromobility |
T5538 |
10024-10029 |
NN |
denotes |
shift |
T5539 |
10030-10035 |
NN |
denotes |
assay |
T5540 |
10036-10037 |
-LRB- |
denotes |
( |
T5541 |
10037-10041 |
NN |
denotes |
EMSA |
T5542 |
10041-10042 |
-RRB- |
denotes |
) |
T5543 |
10043-10045 |
IN |
denotes |
in |
T5544 |
10046-10054 |
NN |
denotes |
melanoma |
T5545 |
10055-10061 |
NN |
denotes |
tissue |
T5546 |
10063-10066 |
DT |
denotes |
The |
T5547 |
10067-10081 |
RB |
denotes |
constitutively |
T5548 |
10082-10091 |
VB |
denotes |
activated |
T5549 |
10092-10095 |
NN |
denotes |
DNA |
T5550 |
10096-10103 |
NN |
denotes |
binding |
T5551 |
10104-10112 |
NN |
denotes |
activity |
T5552 |
10113-10116 |
VB |
denotes |
was |
T5553 |
10117-10124 |
VB |
denotes |
reduced |
T5554 |
10125-10127 |
IN |
denotes |
in |
T5555 |
10128-10131 |
DT |
denotes |
the |
T5556 |
10132-10139 |
NN |
denotes |
CCR5−/− |
T5557 |
10140-10144 |
NN |
denotes |
mice |
T5558 |
10145-10150 |
NN |
denotes |
tumor |
T5559 |
10151-10157 |
NN |
denotes |
tissue |
T5560 |
10158-10159 |
-LRB- |
denotes |
( |
T5561 |
10159-10165 |
NN |
denotes |
Figure |
T5562 |
10166-10168 |
NN |
denotes |
2A |
T5563 |
10168-10169 |
-RRB- |
denotes |
) |
T5564 |
10171-10179 |
RB |
denotes |
Moreover |
T5565 |
10179-10180 |
-COMMA- |
denotes |
, |
T5566 |
10181-10184 |
DT |
denotes |
the |
T5567 |
10185-10198 |
NN |
denotes |
translocation |
T5568 |
10199-10201 |
IN |
denotes |
of |
T5569 |
10202-10205 |
NN |
denotes |
p50 |
T5570 |
10206-10209 |
CC |
denotes |
and |
T5571 |
10210-10215 |
NN |
denotes |
p-p65 |
T5572 |
10216-10220 |
IN |
denotes |
into |
T5573 |
10221-10224 |
DT |
denotes |
the |
T5574 |
10225-10232 |
NN |
denotes |
nucleus |
T5575 |
10233-10240 |
IN |
denotes |
through |
T5576 |
10241-10244 |
DT |
denotes |
the |
T5577 |
10245-10255 |
NN |
denotes |
inhibition |
T5578 |
10256-10258 |
IN |
denotes |
of |
T5579 |
10259-10274 |
NN |
denotes |
phosphorylation |
T5580 |
10275-10277 |
IN |
denotes |
of |
T5581 |
10278-10281 |
NN |
denotes |
IκB |
T5582 |
10282-10285 |
VB |
denotes |
was |
T5583 |
10286-10290 |
RB |
denotes |
also |
T5584 |
10291-10300 |
VB |
denotes |
prevented |
T5585 |
10301-10303 |
IN |
denotes |
in |
T5586 |
10304-10307 |
DT |
denotes |
the |
T5587 |
10308-10313 |
NN |
denotes |
tumor |
T5588 |
10314-10321 |
NN |
denotes |
tissues |
T5589 |
10322-10324 |
IN |
denotes |
of |
T5590 |
10325-10332 |
NN |
denotes |
CCR5−/− |
T5591 |
10333-10337 |
NN |
denotes |
mice |
T5592 |
10338-10339 |
-LRB- |
denotes |
( |
T5593 |
10339-10345 |
NN |
denotes |
Figure |
T5594 |
10346-10348 |
NN |
denotes |
2B |
T5595 |
10348-10349 |
-RRB- |
denotes |
) |
T5596 |
10351-10369 |
NN |
denotes |
Immunofluorescence |
T5597 |
10370-10378 |
NN |
denotes |
analysis |
T5598 |
10379-10383 |
RB |
denotes |
also |
T5599 |
10384-10393 |
VB |
denotes |
confirmed |
T5600 |
10394-10398 |
IN |
denotes |
that |
T5601 |
10399-10402 |
DT |
denotes |
the |
T5602 |
10403-10412 |
NN |
denotes |
intensity |
T5603 |
10413-10415 |
IN |
denotes |
of |
T5604 |
10416-10423 |
JJ |
denotes |
nuclear |
T5605 |
10424-10432 |
NN |
denotes |
staining |
T5606 |
10433-10436 |
IN |
denotes |
for |
T5607 |
10437-10440 |
NN |
denotes |
p50 |
T5608 |
10441-10444 |
VB |
denotes |
had |
T5609 |
10445-10454 |
VB |
denotes |
decreased |
T5610 |
10455-10457 |
IN |
denotes |
in |
T5611 |
10458-10461 |
DT |
denotes |
the |
T5612 |
10462-10467 |
NN |
denotes |
tumor |
T5613 |
10468-10475 |
NN |
denotes |
tissues |
T5614 |
10476-10478 |
IN |
denotes |
of |
T5615 |
10479-10486 |
NN |
denotes |
CCR5−/− |
T5616 |
10487-10491 |
NN |
denotes |
mice |
T5617 |
10492-10493 |
-LRB- |
denotes |
( |
T5618 |
10493-10499 |
NN |
denotes |
Figure |
T5619 |
10500-10502 |
NN |
denotes |
2C |
T5620 |
10502-10503 |
-RRB- |
denotes |
) |
T17796 |
10609-10610 |
DT |
denotes |
A |
T17797 |
10610-10611 |
-COMMA- |
denotes |
, |
T17798 |
10612-10615 |
DT |
denotes |
The |
T17799 |
10616-10619 |
NN |
denotes |
DNA |
T17800 |
10620-10627 |
NN |
denotes |
binding |
T17801 |
10628-10636 |
NN |
denotes |
activity |
T17802 |
10637-10639 |
IN |
denotes |
of |
T17803 |
10640-10645 |
NN |
denotes |
NF-κB |
T17804 |
10646-10649 |
VB |
denotes |
was |
T17805 |
10650-10660 |
VB |
denotes |
determined |
T17806 |
10661-10663 |
IN |
denotes |
in |
T17807 |
10664-10667 |
DT |
denotes |
the |
T17808 |
10668-10675 |
JJ |
denotes |
nuclear |
T17809 |
10676-10684 |
NN |
denotes |
extracts |
T17810 |
10685-10687 |
IN |
denotes |
of |
T17811 |
10688-10691 |
DT |
denotes |
the |
T17812 |
10692-10699 |
NN |
denotes |
CCR5−/− |
T17813 |
10700-10704 |
NN |
denotes |
mice |
T17814 |
10705-10708 |
CC |
denotes |
and |
T17815 |
10709-10716 |
JJ |
denotes |
CCR5+/+ |
T17816 |
10717-10721 |
NN |
denotes |
mice |
T17817 |
10722-10727 |
NN |
denotes |
tumor |
T17818 |
10728-10735 |
NN |
denotes |
tissues |
T17819 |
10736-10738 |
IN |
denotes |
by |
T17820 |
10739-10743 |
NN |
denotes |
EMSA |
T17821 |
10744-10753 |
VB |
denotes |
described |
T17822 |
10754-10756 |
IN |
denotes |
in |
T17823 |
10757-10765 |
NN |
denotes |
material |
T17824 |
10766-10769 |
CC |
denotes |
and |
T17825 |
10770-10777 |
NN |
denotes |
methods |
T17826 |
10779-10780 |
NN |
denotes |
B |
T17827 |
10780-10781 |
-COMMA- |
denotes |
, |
T17828 |
10782-10792 |
NN |
denotes |
Expression |
T17829 |
10793-10795 |
IN |
denotes |
of |
T17830 |
10796-10799 |
NN |
denotes |
p50 |
T17831 |
10800-10803 |
CC |
denotes |
and |
T17832 |
10804-10807 |
NN |
denotes |
p65 |
T17833 |
10808-10823 |
NN |
denotes |
phosphorylation |
T17834 |
10824-10826 |
IN |
denotes |
in |
T17835 |
10827-10834 |
JJ |
denotes |
nuclear |
T17836 |
10835-10843 |
NN |
denotes |
extracts |
T17837 |
10844-10845 |
-LRB- |
denotes |
( |
T17838 |
10845-10847 |
NN |
denotes |
NE |
T17839 |
10847-10848 |
-RRB- |
denotes |
) |
T17840 |
10848-10849 |
-COMMA- |
denotes |
, |
T17841 |
10850-10853 |
CC |
denotes |
and |
T17842 |
10854-10857 |
NN |
denotes |
IκB |
T17843 |
10858-10861 |
CC |
denotes |
and |
T17844 |
10862-10865 |
NN |
denotes |
IκB |
T17845 |
10866-10881 |
NN |
denotes |
phosphorylation |
T17846 |
10882-10884 |
IN |
denotes |
in |
T17847 |
10885-10888 |
DT |
denotes |
the |
T17848 |
10889-10896 |
NN |
denotes |
cytosol |
T17849 |
10897-10898 |
-LRB- |
denotes |
( |
T17850 |
10898-10900 |
NN |
denotes |
CE |
T17851 |
10900-10901 |
-RRB- |
denotes |
) |
T17852 |
10902-10912 |
VB |
denotes |
determined |
T17853 |
10913-10915 |
IN |
denotes |
by |
T17854 |
10916-10923 |
JJ |
denotes |
Western |
T17855 |
10924-10932 |
NN |
denotes |
blotting |
T17856 |
10934-10935 |
NN |
denotes |
C |
T17857 |
10935-10936 |
-COMMA- |
denotes |
, |
T17858 |
10937-10956 |
NN |
denotes |
Immunolfluorescence |
T17859 |
10957-10965 |
NN |
denotes |
analysis |
T17860 |
10966-10968 |
IN |
denotes |
of |
T17861 |
10969-10972 |
NN |
denotes |
p50 |
T17862 |
10973-10982 |
VB |
denotes |
confirmed |
T17863 |
10983-10987 |
IN |
denotes |
that |
T17864 |
10988-10991 |
DT |
denotes |
the |
T17865 |
10992-11003 |
NN |
denotes |
intensities |
T17866 |
11004-11006 |
IN |
denotes |
of |
T17867 |
11007-11014 |
JJ |
denotes |
nuclear |
T17868 |
11015-11023 |
NN |
denotes |
staining |
T17869 |
11024-11027 |
IN |
denotes |
for |
T17870 |
11028-11031 |
NN |
denotes |
p50 |
T17871 |
11032-11036 |
VB |
denotes |
were |
T17872 |
11037-11046 |
VB |
denotes |
decreased |
T17873 |
11047-11049 |
IN |
denotes |
in |
T17874 |
11050-11053 |
DT |
denotes |
the |
T17875 |
11054-11059 |
NN |
denotes |
tumor |
T17876 |
11060-11067 |
NN |
denotes |
tissues |
T17877 |
11068-11070 |
IN |
denotes |
of |
T17878 |
11071-11078 |
NN |
denotes |
CCR5−/− |
T17879 |
11079-11083 |
NN |
denotes |
mice |
T17880 |
11085-11089 |
NN |
denotes |
Data |
T17881 |
11090-11093 |
VB |
denotes |
are |
T17882 |
11094-11099 |
NN |
denotes |
means |
T17883 |
11100-11101 |
VB |
denotes |
± |
T17884 |
11102-11106 |
NNP |
denotes |
S.D. |
T17885 |
11107-11109 |
IN |
denotes |
of |
T17886 |
11110-11114 |
CD |
denotes |
four |
T17887 |
11115-11127 |
JJ |
denotes |
experimental |
T17888 |
11128-11136 |
NN |
denotes |
animals. |
T17889 |
11137-11138 |
SYM |
denotes |
* |
T17890 |
11139-11148 |
VB |
denotes |
indicates |
T17891 |
11149-11160 |
JJ |
denotes |
significant |
T17892 |
11161-11171 |
NN |
denotes |
difference |
T17893 |
11172-11176 |
IN |
denotes |
from |
T17894 |
11177-11184 |
JJ |
denotes |
CCR5+/+ |
T17895 |
11185-11189 |
NN |
denotes |
mice |
T17896 |
11190-11191 |
-LRB- |
denotes |
( |
T17897 |
11191-11192 |
NN |
denotes |
p |
T17898 |
11192-11193 |
SYM |
denotes |
< |
T17899 |
11193-11197 |
CD |
denotes |
0.05 |
T17900 |
11197-11198 |
-RRB- |
denotes |
) |
T17901 |
11200-11205 |
NN |
denotes |
Scale |
T17902 |
11206-11209 |
NN |
denotes |
bar |
T17903 |
11210-11219 |
VB |
denotes |
indicates |
T17904 |
11220-11222 |
CD |
denotes |
50 |
T17905 |
11223-11225 |
NN |
denotes |
µm |
T18249 |
11228-11237 |
NN |
denotes |
Induction |
T6030 |
11228-11237 |
NN |
denotes |
Induction |
T18250 |
11238-11240 |
IN |
denotes |
of |
T6031 |
11238-11240 |
IN |
denotes |
of |
T18251 |
11241-11250 |
JJ |
denotes |
Apoptotic |
T6032 |
11241-11250 |
NNP |
denotes |
Apoptotic |
T18252 |
11251-11255 |
NN |
denotes |
Cell |
T6033 |
11251-11255 |
NNP |
denotes |
Cell |
T18253 |
11256-11261 |
NN |
denotes |
Death |
T6034 |
11256-11261 |
NNP |
denotes |
Death |
T6035 |
11262-11265 |
CC |
denotes |
and |
T6036 |
11266-11276 |
NN |
denotes |
Inhibition |
T6037 |
11277-11279 |
IN |
denotes |
of |
T6038 |
11280-11283 |
DT |
denotes |
the |
T6039 |
11284-11294 |
NN |
denotes |
Expression |
T6040 |
11295-11297 |
IN |
denotes |
of |
T6041 |
11298-11312 |
JJ |
denotes |
Anti-apoptotic |
T6042 |
11313-11321 |
NN |
denotes |
Proteins |
T6043 |
11322-11324 |
IN |
denotes |
in |
T6044 |
11325-11332 |
NN |
denotes |
CCR5−/− |
T6045 |
11333-11337 |
NN |
denotes |
Mice |
T6046 |
11338-11340 |
TO |
denotes |
To |
T6047 |
11341-11344 |
VB |
denotes |
see |
T6048 |
11345-11352 |
IN |
denotes |
whether |
T6049 |
11353-11363 |
NN |
denotes |
inhibition |
T6050 |
11364-11366 |
IN |
denotes |
of |
T6051 |
11367-11372 |
NN |
denotes |
NF-κB |
T6052 |
11373-11381 |
NN |
denotes |
activity |
T6053 |
11382-11389 |
VB |
denotes |
results |
T6054 |
11390-11392 |
IN |
denotes |
in |
T6055 |
11393-11396 |
DT |
denotes |
the |
T6056 |
11397-11406 |
NN |
denotes |
induction |
T6057 |
11407-11409 |
IN |
denotes |
of |
T6058 |
11410-11419 |
JJ |
denotes |
apoptotic |
T6059 |
11420-11424 |
NN |
denotes |
cell |
T6060 |
11425-11430 |
NN |
denotes |
death |
T6061 |
11431-11434 |
CC |
denotes |
and |
T6062 |
11435-11445 |
NN |
denotes |
expression |
T6063 |
11446-11448 |
IN |
denotes |
of |
T6064 |
11449-11454 |
NN |
denotes |
NF-κB |
T6065 |
11455-11461 |
NN |
denotes |
target |
T6066 |
11462-11471 |
JJ |
denotes |
apoptotic |
T6067 |
11472-11476 |
NN |
denotes |
cell |
T6068 |
11477-11482 |
NN |
denotes |
death |
T6069 |
11483-11493 |
JJ |
denotes |
regulatory |
T6070 |
11494-11501 |
NN |
denotes |
protein |
T6071 |
11501-11502 |
-COMMA- |
denotes |
, |
T6072 |
11503-11506 |
DT |
denotes |
the |
T6073 |
11507-11513 |
NN |
denotes |
levels |
T6074 |
11514-11516 |
IN |
denotes |
of |
T6075 |
11517-11526 |
JJ |
denotes |
apoptotic |
T6076 |
11527-11531 |
NN |
denotes |
cell |
T6077 |
11532-11537 |
NN |
denotes |
death |
T6078 |
11538-11541 |
CC |
denotes |
and |
T6079 |
11542-11552 |
NN |
denotes |
expression |
T6080 |
11553-11555 |
IN |
denotes |
of |
T6081 |
11556-11565 |
JJ |
denotes |
apoptotic |
T6082 |
11566-11570 |
NN |
denotes |
cell |
T6083 |
11571-11576 |
NN |
denotes |
death |
T6084 |
11577-11587 |
JJ |
denotes |
regulatory |
T6085 |
11588-11596 |
NN |
denotes |
proteins |
T6086 |
11597-11601 |
VB |
denotes |
were |
T6087 |
11602-11610 |
VB |
denotes |
assessed |
T6088 |
11612-11621 |
JJ |
denotes |
Apoptotic |
T6089 |
11622-11626 |
NN |
denotes |
cell |
T6090 |
11627-11632 |
NN |
denotes |
death |
T6091 |
11633-11635 |
IN |
denotes |
in |
T6092 |
11636-11639 |
DT |
denotes |
the |
T6093 |
11640-11645 |
NN |
denotes |
tumor |
T6094 |
11646-11654 |
NN |
denotes |
sections |
T6095 |
11655-11659 |
VB |
denotes |
were |
T6096 |
11660-11669 |
VB |
denotes |
evaluated |
T6097 |
11670-11672 |
IN |
denotes |
in |
T6098 |
11673-11676 |
DT |
denotes |
the |
T6099 |
11677-11684 |
NN |
denotes |
CCR5+/+ |
T6100 |
11685-11688 |
CC |
denotes |
and |
T6101 |
11689-11696 |
NN |
denotes |
CCR5−/− |
T6102 |
11697-11701 |
NN |
denotes |
mice |
T6103 |
11702-11706 |
WDT |
denotes |
that |
T6104 |
11707-11711 |
VB |
denotes |
were |
T6105 |
11712-11722 |
VB |
denotes |
inoculated |
T6106 |
11723-11727 |
IN |
denotes |
with |
T6107 |
11728-11736 |
NN |
denotes |
melanoma |
T6108 |
11737-11742 |
NN |
denotes |
cells |
T6109 |
11744-11749 |
NN |
denotes |
TUNEL |
T6110 |
11750-11758 |
NN |
denotes |
staining |
T6111 |
11759-11767 |
VB |
denotes |
revealed |
T6112 |
11768-11769 |
DT |
denotes |
a |
T6113 |
11770-11776 |
JJ |
denotes |
higher |
T6114 |
11777-11786 |
NN |
denotes |
frequency |
T6115 |
11787-11789 |
IN |
denotes |
of |
T6116 |
11790-11799 |
JJ |
denotes |
apoptotic |
T6117 |
11800-11804 |
NN |
denotes |
cell |
T6118 |
11805-11810 |
NN |
denotes |
death |
T6119 |
11811-11813 |
IN |
denotes |
in |
T6120 |
11814-11817 |
DT |
denotes |
the |
T6121 |
11818-11823 |
NN |
denotes |
tumor |
T6122 |
11824-11831 |
NN |
denotes |
tissues |
T6123 |
11832-11834 |
IN |
denotes |
of |
T6124 |
11835-11838 |
DT |
denotes |
the |
T6125 |
11839-11846 |
NN |
denotes |
CCR5−/− |
T6126 |
11847-11851 |
NN |
denotes |
mice |
T6127 |
11852-11856 |
IN |
denotes |
than |
T6128 |
11857-11861 |
DT |
denotes |
that |
T6129 |
11862-11864 |
IN |
denotes |
of |
T6130 |
11865-11868 |
DT |
denotes |
the |
T6131 |
11869-11876 |
JJ |
denotes |
CCR5+/+ |
T6132 |
11877-11881 |
NN |
denotes |
mice |
T6133 |
11882-11883 |
-LRB- |
denotes |
( |
T6134 |
11883-11889 |
NN |
denotes |
Figure |
T6135 |
11890-11892 |
NN |
denotes |
3A |
T6136 |
11892-11893 |
-RRB- |
denotes |
) |
T6137 |
11895-11914 |
JJ |
denotes |
Immunohistochemical |
T6138 |
11915-11918 |
CC |
denotes |
and |
T6139 |
11919-11937 |
NN |
denotes |
immunofluorescence |
T6140 |
11938-11944 |
VB |
denotes |
showed |
T6141 |
11945-11949 |
IN |
denotes |
that |
T6142 |
11950-11954 |
JJ |
denotes |
high |
T6143 |
11955-11961 |
NN |
denotes |
levels |
T6144 |
11962-11964 |
IN |
denotes |
of |
T6145 |
11965-11972 |
VB |
denotes |
cleaved |
T6146 |
11973-11982 |
NN |
denotes |
caspase-3 |
T6147 |
11983-11986 |
CC |
denotes |
and |
T6148 |
11987-11990 |
NN |
denotes |
Bax |
T6149 |
11991-11995 |
VB |
denotes |
were |
T6150 |
11996-12001 |
VB |
denotes |
found |
T6151 |
12002-12006 |
RB |
denotes |
more |
T6152 |
12007-12017 |
RB |
denotes |
frequently |
T6153 |
12018-12020 |
IN |
denotes |
in |
T6154 |
12021-12024 |
DT |
denotes |
the |
T6155 |
12025-12032 |
NN |
denotes |
CCR5−/− |
T6156 |
12033-12037 |
NN |
denotes |
mice |
T6157 |
12038-12042 |
IN |
denotes |
than |
T6158 |
12043-12045 |
IN |
denotes |
in |
T6159 |
12046-12049 |
DT |
denotes |
the |
T6160 |
12050-12057 |
JJ |
denotes |
CCR5+/+ |
T6161 |
12058-12062 |
NN |
denotes |
mice |
T6162 |
12063-12064 |
-LRB- |
denotes |
( |
T6163 |
12064-12070 |
NN |
denotes |
Figure |
T6164 |
12071-12073 |
NN |
denotes |
3B |
T6165 |
12074-12077 |
CC |
denotes |
and |
T6166 |
12078-12080 |
NN |
denotes |
3C |
T6167 |
12080-12081 |
-RRB- |
denotes |
) |
T6168 |
12083-12093 |
JJ |
denotes |
Consistent |
T6169 |
12094-12098 |
IN |
denotes |
with |
T6170 |
12099-12102 |
DT |
denotes |
the |
T6171 |
12103-12122 |
JJ |
denotes |
immunohistochemical |
T6172 |
12123-12127 |
NN |
denotes |
data |
T6173 |
12127-12128 |
-COMMA- |
denotes |
, |
T6174 |
12129-12136 |
JJ |
denotes |
Western |
T6175 |
12137-12141 |
NN |
denotes |
blot |
T6176 |
12142-12150 |
NN |
denotes |
analysis |
T6177 |
12151-12153 |
IN |
denotes |
of |
T6178 |
12154-12159 |
NN |
denotes |
tumor |
T6179 |
12160-12168 |
NN |
denotes |
proteins |
T6180 |
12169-12175 |
VB |
denotes |
showed |
T6181 |
12176-12183 |
JJ |
denotes |
greater |
T6182 |
12184-12193 |
VB |
denotes |
increased |
T6183 |
12194-12200 |
NN |
denotes |
levels |
T6184 |
12201-12203 |
IN |
denotes |
of |
T6185 |
12204-12211 |
VB |
denotes |
cleaved |
T6186 |
12212-12221 |
NN |
denotes |
caspase-3 |
T6187 |
12221-12222 |
-COMMA- |
denotes |
, |
T6188 |
12223-12230 |
VB |
denotes |
cleaved |
T6189 |
12231-12240 |
NN |
denotes |
caspase-9 |
T6190 |
12240-12241 |
-COMMA- |
denotes |
, |
T6191 |
12242-12249 |
VB |
denotes |
cleaved |
T6192 |
12250-12254 |
NN |
denotes |
PARP |
T6193 |
12255-12258 |
CC |
denotes |
and |
T6194 |
12259-12262 |
NN |
denotes |
Bax |
T6195 |
12262-12263 |
-COMMA- |
denotes |
, |
T6196 |
12264-12271 |
IN |
denotes |
whereas |
T6197 |
12272-12275 |
DT |
denotes |
the |
T6198 |
12276-12282 |
NN |
denotes |
levels |
T6199 |
12283-12285 |
IN |
denotes |
of |
T6200 |
12286-12291 |
NN |
denotes |
Bcl-2 |
T6201 |
12292-12295 |
CC |
denotes |
and |
T6202 |
12296-12302 |
NN |
denotes |
C-IAP1 |
T6203 |
12303-12307 |
VB |
denotes |
were |
T6204 |
12308-12321 |
RB |
denotes |
significantly |
T6205 |
12322-12331 |
VB |
denotes |
decreased |
T6206 |
12332-12334 |
IN |
denotes |
in |
T6207 |
12335-12342 |
NN |
denotes |
CCR5−/− |
T6208 |
12343-12347 |
NN |
denotes |
mice |
T6209 |
12348-12355 |
NN |
denotes |
tissues |
T6210 |
12356-12357 |
-LRB- |
denotes |
( |
T6211 |
12357-12363 |
NN |
denotes |
Figure |
T6212 |
12364-12366 |
NN |
denotes |
3D |
T6213 |
12366-12367 |
-RRB- |
denotes |
) |
T18254 |
12447-12449 |
IN |
denotes |
in |
T18255 |
12450-12455 |
NN |
denotes |
tumor |
T18256 |
12456-12463 |
NN |
denotes |
tissues |
T18257 |
12464-12466 |
IN |
denotes |
of |
T18258 |
12467-12471 |
NN |
denotes |
CCR5 |
T18259 |
12472-12475 |
NN |
denotes |
−/− |
T18260 |
12476-12480 |
NN |
denotes |
mice |
T18261 |
12482-12483 |
DT |
denotes |
A |
T18262 |
12483-12484 |
-COMMA- |
denotes |
, |
T18263 |
12485-12494 |
JJ |
denotes |
Apoptotic |
T18264 |
12495-12500 |
NN |
denotes |
cells |
T18265 |
12501-12503 |
IN |
denotes |
in |
T18266 |
12504-12509 |
NN |
denotes |
tumor |
T18267 |
12510-12518 |
NN |
denotes |
sections |
T18268 |
12519-12523 |
VB |
denotes |
were |
T18269 |
12524-12532 |
VB |
denotes |
examined |
T18270 |
12533-12535 |
IN |
denotes |
by |
T18271 |
12536-12548 |
NN |
denotes |
fluorescence |
T18272 |
12549-12559 |
NN |
denotes |
microscopy |
T18273 |
12560-12565 |
IN |
denotes |
after |
T18274 |
12566-12570 |
NN |
denotes |
DAPI |
T18275 |
12571-12574 |
CC |
denotes |
and |
T18276 |
12575-12580 |
NN |
denotes |
TUNEL |
T18277 |
12581-12589 |
NN |
denotes |
staining |
T18278 |
12590-12592 |
IN |
denotes |
as |
T18279 |
12593-12602 |
VB |
denotes |
described |
T18280 |
12603-12605 |
IN |
denotes |
in |
T18281 |
12606-12614 |
NN |
denotes |
material |
T18282 |
12615-12618 |
CC |
denotes |
and |
T18283 |
12619-12626 |
NN |
denotes |
methods |
T18284 |
12628-12631 |
DT |
denotes |
The |
T18285 |
12632-12641 |
JJ |
denotes |
apoptotic |
T18286 |
12642-12647 |
NN |
denotes |
index |
T18287 |
12648-12651 |
VB |
denotes |
was |
T18288 |
12652-12662 |
VB |
denotes |
determined |
T18289 |
12663-12665 |
IN |
denotes |
as |
T18290 |
12666-12669 |
DT |
denotes |
the |
T18291 |
12670-12676 |
NN |
denotes |
number |
T18292 |
12677-12679 |
IN |
denotes |
of |
T18293 |
12680-12692 |
JJ |
denotes |
DAPI-stained |
T18294 |
12692-12693 |
-COMMA- |
denotes |
, |
T18295 |
12694-12708 |
JJ |
denotes |
TUNEL-positive |
T18296 |
12709-12714 |
NN |
denotes |
cells |
T18297 |
12715-12719 |
WDT |
denotes |
that |
T18298 |
12720-12724 |
VB |
denotes |
were |
T18299 |
12725-12732 |
VB |
denotes |
counted |
T18300 |
12734-12740 |
NN |
denotes |
Values |
T18301 |
12741-12744 |
VB |
denotes |
are |
T18302 |
12745-12748 |
DT |
denotes |
the |
T18303 |
12749-12753 |
JJ |
denotes |
mean |
T18304 |
12754-12755 |
NN |
denotes |
± |
T18305 |
12756-12760 |
NNP |
denotes |
S.D. |
T18306 |
12761-12763 |
IN |
denotes |
of |
T18307 |
12764-12768 |
CD |
denotes |
four |
T18308 |
12769-12781 |
JJ |
denotes |
experimental |
T18309 |
12782-12790 |
NN |
denotes |
animals. |
T18310 |
12791-12792 |
SYM |
denotes |
* |
T18311 |
12793-12802 |
VB |
denotes |
indicates |
T18312 |
12803-12816 |
RB |
denotes |
statistically |
T18313 |
12817-12828 |
JJ |
denotes |
significant |
T18314 |
12829-12840 |
NN |
denotes |
differences |
T18315 |
12841-12845 |
IN |
denotes |
from |
T18316 |
12846-12853 |
JJ |
denotes |
CCR5+/+ |
T18317 |
12854-12858 |
NN |
denotes |
mice |
T18318 |
12860-12865 |
NN |
denotes |
Scale |
T18319 |
12866-12869 |
NN |
denotes |
bar |
T18320 |
12870-12879 |
VB |
denotes |
indicates |
T18321 |
12880-12882 |
CD |
denotes |
50 |
T18322 |
12883-12885 |
NN |
denotes |
µm |
T18323 |
12887-12888 |
NN |
denotes |
B |
T18324 |
12889-12892 |
CC |
denotes |
and |
T18325 |
12893-12894 |
NN |
denotes |
C |
T18326 |
12894-12895 |
-COMMA- |
denotes |
, |
T18327 |
12896-12905 |
JJ |
denotes |
Apoptotic |
T18328 |
12906-12913 |
NN |
denotes |
protein |
T18329 |
12914-12915 |
-LRB- |
denotes |
( |
T18330 |
12915-12922 |
VB |
denotes |
cleaved |
T18331 |
12923-12932 |
NN |
denotes |
caspase-3 |
T18332 |
12933-12936 |
CC |
denotes |
and |
T18333 |
12937-12940 |
NN |
denotes |
Bax |
T18334 |
12940-12941 |
-RRB- |
denotes |
) |
T18335 |
12942-12944 |
IN |
denotes |
in |
T18336 |
12945-12950 |
NN |
denotes |
tumor |
T18337 |
12951-12959 |
NN |
denotes |
sections |
T18338 |
12960-12964 |
VB |
denotes |
were |
T18339 |
12965-12973 |
VB |
denotes |
detected |
T18340 |
12974-12976 |
IN |
denotes |
by |
T18341 |
12977-12995 |
NN |
denotes |
immunofluorescence |
T18342 |
12996-13001 |
NN |
denotes |
assay |
T18343 |
13003-13006 |
DT |
denotes |
The |
T18344 |
13007-13015 |
JJ |
denotes |
reactive |
T18345 |
13016-13020 |
NN |
denotes |
cell |
T18346 |
13021-13027 |
NN |
denotes |
number |
T18347 |
13028-13031 |
VB |
denotes |
was |
T18348 |
13032-13042 |
VB |
denotes |
determined |
T18349 |
13043-13045 |
IN |
denotes |
as |
T18350 |
13046-13049 |
DT |
denotes |
the |
T18351 |
13050-13056 |
NN |
denotes |
number |
T18352 |
13057-13059 |
IN |
denotes |
of |
T18353 |
13060-13072 |
JJ |
denotes |
DAPI-stained |
T18354 |
13072-13073 |
-COMMA- |
denotes |
, |
T18355 |
13074-13082 |
JJ |
denotes |
Specific |
T18356 |
13083-13091 |
NN |
denotes |
antibody |
T18357 |
13092-13093 |
-LRB- |
denotes |
( |
T18358 |
13093-13100 |
VB |
denotes |
cleaved |
T18359 |
13101-13110 |
NN |
denotes |
caspase-3 |
T18360 |
13111-13114 |
CC |
denotes |
and |
T18361 |
13115-13118 |
NN |
denotes |
Bax |
T18362 |
13118-13119 |
-RRB- |
denotes |
) |
T18363 |
13119-13128 |
JJ |
denotes |
-positive |
T18364 |
13129-13134 |
NN |
denotes |
cells |
T18365 |
13135-13139 |
WDT |
denotes |
that |
T18366 |
13140-13144 |
VB |
denotes |
were |
T18367 |
13145-13152 |
VB |
denotes |
counted |
T18368 |
13154-13160 |
NN |
denotes |
Values |
T18369 |
13161-13164 |
VB |
denotes |
are |
T18370 |
13165-13168 |
DT |
denotes |
the |
T18371 |
13169-13173 |
JJ |
denotes |
mean |
T18372 |
13174-13175 |
NN |
denotes |
± |
T18373 |
13176-13180 |
NNP |
denotes |
S.D. |
T18374 |
13181-13183 |
IN |
denotes |
of |
T18375 |
13184-13188 |
CD |
denotes |
four |
T18376 |
13189-13201 |
JJ |
denotes |
experimental |
T18377 |
13202-13210 |
NN |
denotes |
animals. |
T18378 |
13211-13212 |
SYM |
denotes |
* |
T18379 |
13213-13222 |
VB |
denotes |
indicates |
T18380 |
13223-13236 |
RB |
denotes |
statistically |
T18381 |
13237-13248 |
JJ |
denotes |
significant |
T18382 |
13249-13260 |
NN |
denotes |
differences |
T18383 |
13261-13265 |
IN |
denotes |
from |
T18384 |
13266-13273 |
JJ |
denotes |
CCR5+/+ |
T18385 |
13274-13278 |
NN |
denotes |
mice |
T18386 |
13280-13285 |
NN |
denotes |
Scale |
T18387 |
13286-13289 |
NN |
denotes |
bar |
T18388 |
13290-13299 |
VB |
denotes |
indicates |
T18389 |
13300-13302 |
CD |
denotes |
50 |
T18390 |
13303-13305 |
NN |
denotes |
µm |
T18391 |
13307-13308 |
NN |
denotes |
D |
T18392 |
13308-13309 |
-COMMA- |
denotes |
, |
T18393 |
13310-13313 |
DT |
denotes |
The |
T18394 |
13314-13324 |
NN |
denotes |
expression |
T18395 |
13325-13327 |
IN |
denotes |
of |
T18396 |
13328-13337 |
JJ |
denotes |
apoptotic |
T18397 |
13338-13346 |
NN |
denotes |
proteins |
T18398 |
13347-13350 |
VB |
denotes |
was |
T18399 |
13351-13359 |
VB |
denotes |
detected |
T18400 |
13360-13362 |
IN |
denotes |
by |
T18401 |
13363-13370 |
JJ |
denotes |
Western |
T18402 |
13371-13379 |
NN |
denotes |
blotting |
T18403 |
13380-13385 |
VB |
denotes |
using |
T18404 |
13386-13394 |
JJ |
denotes |
specific |
T18405 |
13395-13405 |
NN |
denotes |
antibodies |
T18406 |
13405-13406 |
-COLON- |
denotes |
; |
T18407 |
13407-13414 |
VB |
denotes |
cleaved |
T18408 |
13415-13424 |
NN |
denotes |
caspase-3 |
T18409 |
13424-13425 |
-COMMA- |
denotes |
, |
T18410 |
13426-13433 |
VB |
denotes |
cleaved |
T18411 |
13434-13443 |
NN |
denotes |
caspase-9 |
T18412 |
13443-13444 |
-COMMA- |
denotes |
, |
T18413 |
13445-13452 |
VB |
denotes |
cleaved |
T18414 |
13453-13457 |
NN |
denotes |
PARP |
T18415 |
13457-13458 |
-COMMA- |
denotes |
, |
T18416 |
13459-13462 |
NN |
denotes |
Bax |
T18417 |
13462-13463 |
-COMMA- |
denotes |
, |
T18418 |
13464-13469 |
NN |
denotes |
Bcl-2 |
T18419 |
13470-13473 |
CC |
denotes |
and |
T18420 |
13474-13480 |
NN |
denotes |
c-IAP1 |
T18421 |
13481-13483 |
IN |
denotes |
in |
T18422 |
13484-13487 |
DT |
denotes |
the |
T18423 |
13488-13493 |
NN |
denotes |
tumor |
T18424 |
13494-13501 |
NN |
denotes |
tissues |
T18425 |
13503-13506 |
DT |
denotes |
The |
T18426 |
13507-13514 |
JJ |
denotes |
β-actin |
T18427 |
13515-13522 |
NN |
denotes |
protein |
T18428 |
13523-13526 |
VB |
denotes |
was |
T18429 |
13527-13531 |
VB |
denotes |
used |
T18430 |
13532-13534 |
IN |
denotes |
as |
T18431 |
13535-13537 |
DT |
denotes |
an |
T18432 |
13538-13546 |
JJ |
denotes |
internal |
T18433 |
13547-13554 |
NN |
denotes |
control |
T18434 |
13556-13560 |
DT |
denotes |
Each |
T18435 |
13561-13565 |
NN |
denotes |
band |
T18436 |
13566-13568 |
VB |
denotes |
is |
T18437 |
13569-13583 |
JJ |
denotes |
representative |
T18438 |
13584-13586 |
IN |
denotes |
of |
T18439 |
13587-13592 |
CD |
denotes |
three |
T18440 |
13593-13604 |
JJ |
denotes |
independent |
T18441 |
13605-13617 |
JJ |
denotes |
experimental |
T18442 |
13618-13625 |
NN |
denotes |
results |
T18443 |
13627-13631 |
NN |
denotes |
Data |
T18444 |
13632-13635 |
VB |
denotes |
are |
T18445 |
13636-13641 |
NN |
denotes |
means |
T18446 |
13642-13643 |
VB |
denotes |
± |
T18447 |
13644-13648 |
NNP |
denotes |
S.D. |
T18448 |
13649-13651 |
IN |
denotes |
of |
T18449 |
13652-13657 |
CD |
denotes |
three |
T18450 |
13658-13670 |
JJ |
denotes |
experimental |
T18451 |
13671-13679 |
NN |
denotes |
animals. |
T18452 |
13680-13681 |
SYM |
denotes |
* |
T18453 |
13682-13691 |
VB |
denotes |
indicates |
T18454 |
13692-13703 |
JJ |
denotes |
significant |
T18455 |
13704-13714 |
NN |
denotes |
difference |
T18456 |
13715-13719 |
IN |
denotes |
from |
T18457 |
13720-13727 |
JJ |
denotes |
CCR5+/+ |
T18458 |
13728-13732 |
NN |
denotes |
mice |
T18459 |
13733-13734 |
-LRB- |
denotes |
( |
T18460 |
13734-13735 |
NN |
denotes |
p |
T18461 |
13735-13736 |
SYM |
denotes |
< |
T18462 |
13736-13740 |
CD |
denotes |
0.05 |
T18463 |
13740-13741 |
-RRB- |
denotes |
) |
T18934 |
13744-13756 |
NN |
denotes |
Upregulation |
T6715 |
13744-13756 |
NN |
denotes |
Upregulation |
T18935 |
13757-13759 |
IN |
denotes |
of |
T6716 |
13757-13759 |
IN |
denotes |
of |
T18936 |
13760-13766 |
NN |
denotes |
IL-1Ra |
T6717 |
13760-13766 |
NN |
denotes |
IL-1Ra |
T18937 |
13767-13769 |
IN |
denotes |
in |
T6718 |
13767-13769 |
IN |
denotes |
in |
T18938 |
13770-13773 |
DT |
denotes |
the |
T6719 |
13770-13773 |
DT |
denotes |
the |
T18939 |
13774-13779 |
NN |
denotes |
Tumor |
T6720 |
13774-13779 |
NN |
denotes |
Tumor |
T18940 |
13780-13783 |
CC |
denotes |
and |
T6721 |
13780-13783 |
CC |
denotes |
and |
T18941 |
13784-13790 |
NN |
denotes |
Spleen |
T6722 |
13784-13790 |
NN |
denotes |
Spleen |
T18942 |
13791-13793 |
IN |
denotes |
of |
T6723 |
13791-13793 |
IN |
denotes |
of |
T18943 |
13794-13801 |
NN |
denotes |
CCR5−/− |
T6724 |
13794-13801 |
NN |
denotes |
CCR5−/− |
T18944 |
13802-13806 |
NN |
denotes |
Mice |
T6725 |
13802-13806 |
NN |
denotes |
Mice |
T6726 |
13807-13809 |
TO |
denotes |
To |
T6727 |
13810-13821 |
VB |
denotes |
investigate |
T6728 |
13822-13825 |
DT |
denotes |
the |
T6729 |
13826-13836 |
NN |
denotes |
difference |
T6730 |
13837-13839 |
IN |
denotes |
in |
T6731 |
13840-13843 |
DT |
denotes |
the |
T6732 |
13844-13852 |
NN |
denotes |
cytokine |
T6733 |
13853-13859 |
NN |
denotes |
levels |
T6734 |
13860-13867 |
IN |
denotes |
between |
T6735 |
13868-13871 |
DT |
denotes |
the |
T6736 |
13872-13877 |
NN |
denotes |
tumor |
T6737 |
13878-13881 |
CC |
denotes |
and |
T6738 |
13882-13888 |
NN |
denotes |
spleen |
T6739 |
13889-13896 |
NN |
denotes |
tissues |
T6740 |
13897-13899 |
IN |
denotes |
of |
T6741 |
13900-13903 |
DT |
denotes |
the |
T6742 |
13904-13911 |
NN |
denotes |
CCR5+/+ |
T6743 |
13912-13915 |
CC |
denotes |
and |
T6744 |
13916-13923 |
NN |
denotes |
CCR5−/− |
T6745 |
13924-13928 |
NN |
denotes |
mice |
T6746 |
13928-13929 |
-COMMA- |
denotes |
, |
T6747 |
13930-13932 |
PRP |
denotes |
we |
T6748 |
13933-13942 |
VB |
denotes |
conducted |
T6749 |
13943-13944 |
DT |
denotes |
a |
T6750 |
13945-13953 |
NN |
denotes |
cytokine |
T6751 |
13954-13959 |
NN |
denotes |
array |
T6752 |
13960-13965 |
NN |
denotes |
assay |
T6753 |
13966-13971 |
VB |
denotes |
using |
T6754 |
13972-13973 |
DT |
denotes |
a |
T6755 |
13974-13979 |
NNP |
denotes |
Mouse |
T6756 |
13980-13988 |
NNP |
denotes |
Proteome |
T6757 |
13989-13994 |
NNP |
denotes |
Array |
T6758 |
13995-13996 |
-LRB- |
denotes |
( |
T6759 |
13996-14002 |
NN |
denotes |
Figure |
T6760 |
14003-14005 |
NN |
denotes |
4A |
T6761 |
14005-14006 |
-RRB- |
denotes |
) |
T6762 |
14008-14013 |
IN |
denotes |
Among |
T6763 |
14014-14016 |
CD |
denotes |
40 |
T6764 |
14017-14023 |
VB |
denotes |
tested |
T6765 |
14024-14033 |
NN |
denotes |
cytokines |
T6766 |
14033-14034 |
-COMMA- |
denotes |
, |
T6767 |
14035-14038 |
DT |
denotes |
the |
T6768 |
14039-14045 |
NN |
denotes |
levels |
T6769 |
14046-14048 |
IN |
denotes |
of |
T6770 |
14049-14055 |
NN |
denotes |
IL-1Ra |
T6771 |
14055-14056 |
-COMMA- |
denotes |
, |
T6772 |
14057-14060 |
NN |
denotes |
MIG |
T6773 |
14060-14061 |
-COMMA- |
denotes |
, |
T6774 |
14062-14068 |
NN |
denotes |
MIP-1α |
T6775 |
14069-14078 |
VB |
denotes |
increased |
T6776 |
14079-14084 |
RB |
denotes |
about |
T6777 |
14085-14088 |
CD |
denotes |
686 |
T6778 |
14088-14089 |
-COMMA- |
denotes |
, |
T6779 |
14090-14091 |
CD |
denotes |
9 |
T6780 |
14092-14095 |
CC |
denotes |
and |
T6781 |
14096-14103 |
RB |
denotes |
25-fold |
T6782 |
14104-14116 |
RB |
denotes |
respectively |
T6783 |
14116-14117 |
-COMMA- |
denotes |
, |
T6784 |
14118-14120 |
IN |
denotes |
in |
T6785 |
14121-14128 |
NN |
denotes |
CCR5−/− |
T6786 |
14129-14133 |
NN |
denotes |
mice |
T6787 |
14134-14142 |
VB |
denotes |
compared |
T6788 |
14143-14145 |
TO |
denotes |
to |
T6789 |
14146-14153 |
JJ |
denotes |
CCR5+/+ |
T6790 |
14154-14158 |
NN |
denotes |
mice |
T6791 |
14160-14165 |
VB |
denotes |
Using |
T6792 |
14166-14170 |
DT |
denotes |
this |
T6793 |
14171-14180 |
NN |
denotes |
technique |
T6794 |
14180-14181 |
-COMMA- |
denotes |
, |
T6795 |
14182-14184 |
DT |
denotes |
no |
T6796 |
14185-14190 |
JJ |
denotes |
other |
T6797 |
14191-14200 |
NN |
denotes |
cytokines |
T6798 |
14201-14205 |
VB |
denotes |
were |
T6799 |
14206-14211 |
VB |
denotes |
found |
T6800 |
14212-14214 |
TO |
denotes |
to |
T6801 |
14215-14217 |
VB |
denotes |
be |
T6802 |
14218-14227 |
JJ |
denotes |
different |
T6803 |
14228-14235 |
IN |
denotes |
between |
T6804 |
14236-14239 |
DT |
denotes |
the |
T6805 |
14240-14247 |
NN |
denotes |
CCR5−/− |
T6806 |
14248-14252 |
NN |
denotes |
mice |
T6807 |
14253-14256 |
CC |
denotes |
and |
T6808 |
14257-14260 |
DT |
denotes |
the |
T6809 |
14261-14268 |
JJ |
denotes |
CCR5+/+ |
T6810 |
14269-14273 |
NN |
denotes |
mice |
T6811 |
14274-14275 |
-LRB- |
denotes |
( |
T6812 |
14275-14281 |
NN |
denotes |
Figure |
T6813 |
14282-14284 |
NN |
denotes |
4B |
T6814 |
14284-14285 |
-RRB- |
denotes |
) |
T6815 |
14287-14294 |
JJ |
denotes |
Similar |
T6816 |
14295-14302 |
JJ |
denotes |
altered |
T6817 |
14303-14311 |
NN |
denotes |
cytokine |
T6818 |
14312-14318 |
NN |
denotes |
levels |
T6819 |
14319-14323 |
VB |
denotes |
were |
T6820 |
14324-14329 |
VB |
denotes |
found |
T6821 |
14330-14332 |
IN |
denotes |
in |
T6822 |
14333-14336 |
DT |
denotes |
the |
T6823 |
14337-14344 |
NN |
denotes |
spleens |
T6824 |
14345-14347 |
IN |
denotes |
of |
T6825 |
14348-14355 |
NN |
denotes |
CCR5−/− |
T6826 |
14356-14360 |
NN |
denotes |
mice |
T6827 |
14361-14362 |
-LRB- |
denotes |
( |
T6828 |
14362-14368 |
NN |
denotes |
Figure |
T6829 |
14369-14371 |
NN |
denotes |
4C |
T6830 |
14371-14372 |
-RRB- |
denotes |
) |
T6831 |
14374-14379 |
IN |
denotes |
Since |
T6832 |
14380-14383 |
DT |
denotes |
the |
T6833 |
14384-14390 |
NN |
denotes |
IL-1Ra |
T6834 |
14391-14396 |
NN |
denotes |
level |
T6835 |
14397-14400 |
VB |
denotes |
was |
T6836 |
14401-14404 |
DT |
denotes |
the |
T6837 |
14405-14409 |
RB |
denotes |
most |
T6838 |
14410-14423 |
RB |
denotes |
significantly |
T6839 |
14424-14432 |
VB |
denotes |
elevated |
T6840 |
14432-14433 |
-COMMA- |
denotes |
, |
T6841 |
14434-14437 |
DT |
denotes |
the |
T6842 |
14438-14448 |
NN |
denotes |
expression |
T6843 |
14449-14451 |
IN |
denotes |
of |
T6844 |
14452-14458 |
NN |
denotes |
IL-1Ra |
T6845 |
14459-14461 |
IN |
denotes |
in |
T6846 |
14462-14467 |
NN |
denotes |
tumor |
T6847 |
14468-14471 |
CC |
denotes |
and |
T6848 |
14472-14478 |
NN |
denotes |
spleen |
T6849 |
14479-14486 |
NN |
denotes |
tissues |
T6850 |
14487-14490 |
VB |
denotes |
was |
T6851 |
14491-14499 |
VB |
denotes |
analyzed |
T6852 |
14500-14502 |
IN |
denotes |
by |
T6853 |
14503-14521 |
NN |
denotes |
immunofluorescence |
T6854 |
14522-14525 |
CC |
denotes |
and |
T6855 |
14526-14533 |
JJ |
denotes |
western |
T6856 |
14534-14542 |
NN |
denotes |
blotting |
T6857 |
14544-14547 |
DT |
denotes |
The |
T6858 |
14548-14558 |
NN |
denotes |
expression |
T6859 |
14559-14561 |
IN |
denotes |
of |
T6860 |
14562-14568 |
NN |
denotes |
IL-1Ra |
T6861 |
14569-14572 |
VB |
denotes |
was |
T6862 |
14573-14584 |
VB |
denotes |
upregulated |
T6863 |
14585-14587 |
IN |
denotes |
in |
T6864 |
14588-14593 |
NN |
denotes |
tumor |
T6865 |
14594-14597 |
CC |
denotes |
and |
T6866 |
14598-14604 |
NN |
denotes |
spleen |
T6867 |
14605-14612 |
NN |
denotes |
tissues |
T6868 |
14613-14615 |
IN |
denotes |
of |
T6869 |
14616-14619 |
DT |
denotes |
the |
T6870 |
14620-14627 |
NN |
denotes |
CCR5−/− |
T6871 |
14628-14632 |
NN |
denotes |
mice |
T6872 |
14633-14634 |
-LRB- |
denotes |
( |
T6873 |
14634-14640 |
NN |
denotes |
Figure |
T6874 |
14641-14645 |
NN |
denotes |
4D-G |
T6875 |
14645-14646 |
-RRB- |
denotes |
) |
T18945 |
14756-14757 |
DT |
denotes |
A |
T18946 |
14757-14758 |
-COMMA- |
denotes |
, |
T18947 |
14759-14765 |
NNP |
denotes |
Figure |
T18948 |
14766-14768 |
NN |
denotes |
4A |
T18949 |
14769-14778 |
VB |
denotes |
indicates |
T18950 |
14779-14784 |
NN |
denotes |
mouse |
T18951 |
14785-14793 |
NN |
denotes |
cytokine |
T18952 |
14794-14799 |
NN |
denotes |
array |
T18953 |
14800-14805 |
NN |
denotes |
panel |
T18954 |
14806-14817 |
VB |
denotes |
coordinates |
T18955 |
14819-14833 |
NN |
denotes |
Nitrocellulose |
T18956 |
14834-14843 |
NN |
denotes |
membranes |
T18957 |
14844-14851 |
VB |
denotes |
contain |
T18958 |
14852-14854 |
CD |
denotes |
40 |
T18959 |
14855-14864 |
JJ |
denotes |
different |
T18960 |
14865-14878 |
JJ |
denotes |
anti-cytokine |
T18961 |
14879-14889 |
NN |
denotes |
antibodies |
T18962 |
14890-14897 |
VB |
denotes |
printed |
T18963 |
14898-14900 |
IN |
denotes |
in |
T18964 |
14901-14910 |
NN |
denotes |
duplicate |
T18965 |
14912-14913 |
NN |
denotes |
B |
T18966 |
14913-14914 |
-COMMA- |
denotes |
, |
T18967 |
14915-14920 |
NN |
denotes |
Mouse |
T18968 |
14921-14929 |
NN |
denotes |
cytokine |
T18969 |
14930-14935 |
NN |
denotes |
array |
T18970 |
14936-14941 |
NN |
denotes |
panel |
T18971 |
14942-14950 |
VB |
denotes |
indicate |
T18972 |
14951-14954 |
DT |
denotes |
the |
T18973 |
14955-14963 |
NN |
denotes |
cytokine |
T18974 |
14964-14974 |
NN |
denotes |
expression |
T18975 |
14975-14985 |
NN |
denotes |
difference |
T18976 |
14986-14988 |
IN |
denotes |
in |
T18977 |
14989-14994 |
NN |
denotes |
tumor |
T18978 |
14995-15002 |
NN |
denotes |
tissues |
T18979 |
15003-15005 |
IN |
denotes |
of |
T18980 |
15006-15013 |
JJ |
denotes |
CCR5+/+ |
T18981 |
15014-15018 |
NN |
denotes |
mice |
T18982 |
15019-15022 |
CC |
denotes |
and |
T18983 |
15023-15030 |
NN |
denotes |
CCR5−/− |
T18984 |
15031-15035 |
NN |
denotes |
mice |
T18985 |
15035-15036 |
-COMMA- |
denotes |
, |
T18986 |
15037-15047 |
RB |
denotes |
especially |
T18987 |
15048-15054 |
NN |
denotes |
IL-1Ra |
T18988 |
15056-15070 |
JJ |
denotes |
Representative |
T18989 |
15071-15075 |
NN |
denotes |
blot |
T18990 |
15076-15080 |
IN |
denotes |
from |
T18991 |
15081-15086 |
CD |
denotes |
three |
T18992 |
15087-15098 |
JJ |
denotes |
independent |
T18993 |
15099-15110 |
NN |
denotes |
experiments |
T18994 |
15111-15113 |
VB |
denotes |
is |
T18995 |
15114-15119 |
VB |
denotes |
shown |
T18996 |
15121-15129 |
JJ |
denotes |
Positive |
T18997 |
15130-15138 |
NN |
denotes |
controls |
T18998 |
15139-15143 |
VB |
denotes |
show |
T18999 |
15144-15147 |
DT |
denotes |
the |
T19000 |
15148-15162 |
NN |
denotes |
manufacturer’s |
T19001 |
15163-15171 |
JJ |
denotes |
internal |
T19002 |
15172-15180 |
JJ |
denotes |
positive |
T19003 |
15181-15188 |
NN |
denotes |
control |
T19004 |
15189-15196 |
NN |
denotes |
samples |
T19005 |
15197-15199 |
IN |
denotes |
on |
T19006 |
15200-15203 |
DT |
denotes |
the |
T19007 |
15204-15212 |
NN |
denotes |
membrane |
T19008 |
15214-15215 |
NN |
denotes |
C |
T19009 |
15215-15216 |
-COMMA- |
denotes |
, |
T19010 |
15217-15224 |
NN |
denotes |
Protein |
T19011 |
15225-15238 |
NN |
denotes |
immune-arrays |
T19012 |
15239-15243 |
VB |
denotes |
were |
T19013 |
15244-15253 |
VB |
denotes |
performed |
T19014 |
15254-15259 |
VB |
denotes |
using |
T19015 |
15260-15265 |
NN |
denotes |
Mouse |
T19016 |
15266-15274 |
NN |
denotes |
cytokine |
T19017 |
15275-15280 |
NN |
denotes |
array |
T19018 |
15281-15283 |
IN |
denotes |
in |
T19019 |
15284-15290 |
NN |
denotes |
spleen |
T19020 |
15291-15298 |
NN |
denotes |
tissues |
T19021 |
15300-15305 |
EX |
denotes |
There |
T19022 |
15306-15310 |
VB |
denotes |
were |
T19023 |
15311-15322 |
NN |
denotes |
differences |
T19024 |
15323-15325 |
IN |
denotes |
in |
T19025 |
15326-15335 |
NN |
denotes |
cytokines |
T19026 |
15336-15343 |
IN |
denotes |
between |
T19027 |
15344-15351 |
JJ |
denotes |
CCR5+/+ |
T19028 |
15352-15356 |
NN |
denotes |
mice |
T19029 |
15357-15360 |
CC |
denotes |
and |
T19030 |
15361-15368 |
NN |
denotes |
CCR5−/− |
T19031 |
15369-15373 |
NN |
denotes |
mice |
T19032 |
15373-15374 |
-COMMA- |
denotes |
, |
T19033 |
15375-15385 |
RB |
denotes |
especially |
T19034 |
15386-15392 |
NN |
denotes |
IL-1Ra |
T19035 |
15394-15408 |
JJ |
denotes |
Representative |
T19036 |
15409-15413 |
NN |
denotes |
blot |
T19037 |
15414-15418 |
IN |
denotes |
from |
T19038 |
15419-15424 |
CD |
denotes |
three |
T19039 |
15425-15436 |
JJ |
denotes |
independent |
T19040 |
15437-15448 |
NN |
denotes |
experiments |
T19041 |
15449-15451 |
VB |
denotes |
is |
T19042 |
15452-15457 |
VB |
denotes |
shown |
T19043 |
15459-15467 |
JJ |
denotes |
Positive |
T19044 |
15468-15476 |
NN |
denotes |
controls |
T19045 |
15477-15481 |
VB |
denotes |
show |
T19046 |
15482-15485 |
DT |
denotes |
the |
T19047 |
15486-15500 |
NN |
denotes |
manufacturer’s |
T19048 |
15501-15509 |
JJ |
denotes |
internal |
T19049 |
15510-15518 |
JJ |
denotes |
positive |
T19050 |
15519-15526 |
NN |
denotes |
control |
T19051 |
15527-15534 |
NN |
denotes |
samples |
T19052 |
15535-15537 |
IN |
denotes |
on |
T19053 |
15538-15541 |
DT |
denotes |
the |
T19054 |
15542-15550 |
NN |
denotes |
membrane |
T19055 |
15552-15553 |
NN |
denotes |
D |
T19056 |
15554-15557 |
CC |
denotes |
and |
T19057 |
15558-15559 |
NN |
denotes |
E |
T19058 |
15559-15560 |
-COMMA- |
denotes |
, |
T19059 |
15561-15580 |
NN |
denotes |
Immunolfluorescence |
T19060 |
15581-15589 |
NN |
denotes |
analysis |
T19061 |
15590-15593 |
VB |
denotes |
was |
T19062 |
15594-15598 |
VB |
denotes |
used |
T19063 |
15599-15601 |
TO |
denotes |
to |
T19064 |
15602-15611 |
VB |
denotes |
determine |
T19065 |
15612-15615 |
DT |
denotes |
the |
T19066 |
15616-15626 |
NN |
denotes |
expression |
T19067 |
15627-15633 |
NN |
denotes |
levels |
T19068 |
15634-15636 |
IN |
denotes |
of |
T19069 |
15637-15643 |
NN |
denotes |
IL-1Ra |
T19070 |
15644-15646 |
IN |
denotes |
in |
T19071 |
15647-15652 |
NN |
denotes |
tumor |
T19072 |
15653-15656 |
CC |
denotes |
and |
T19073 |
15657-15663 |
NN |
denotes |
spleen |
T19074 |
15664-15671 |
NN |
denotes |
tissues |
T19075 |
15673-15676 |
DT |
denotes |
The |
T19076 |
15677-15685 |
JJ |
denotes |
reactive |
T19077 |
15686-15690 |
NN |
denotes |
cell |
T19078 |
15691-15697 |
NN |
denotes |
number |
T19079 |
15698-15701 |
VB |
denotes |
was |
T19080 |
15702-15712 |
VB |
denotes |
determined |
T19081 |
15713-15715 |
IN |
denotes |
as |
T19082 |
15716-15719 |
DT |
denotes |
the |
T19083 |
15720-15726 |
NN |
denotes |
number |
T19084 |
15727-15729 |
IN |
denotes |
of |
T19085 |
15730-15742 |
JJ |
denotes |
DAPI-stained |
T19086 |
15742-15743 |
-COMMA- |
denotes |
, |
T19087 |
15744-15750 |
NN |
denotes |
IL-1Ra |
T19088 |
15751-15768 |
JJ |
denotes |
antibody-positive |
T19089 |
15769-15774 |
NN |
denotes |
cells |
T19090 |
15775-15779 |
WDT |
denotes |
that |
T19091 |
15780-15784 |
VB |
denotes |
were |
T19092 |
15785-15792 |
VB |
denotes |
counted |
T19093 |
15794-15800 |
NN |
denotes |
Values |
T19094 |
15801-15804 |
VB |
denotes |
are |
T19095 |
15805-15808 |
DT |
denotes |
the |
T19096 |
15809-15813 |
JJ |
denotes |
mean |
T19097 |
15814-15815 |
NN |
denotes |
± |
T19098 |
15816-15820 |
NNP |
denotes |
S.D. |
T19099 |
15821-15823 |
IN |
denotes |
of |
T19100 |
15824-15828 |
CD |
denotes |
four |
T19101 |
15829-15841 |
JJ |
denotes |
experimental |
T19102 |
15842-15850 |
NN |
denotes |
animals. |
T19103 |
15851-15852 |
SYM |
denotes |
* |
T19104 |
15853-15862 |
VB |
denotes |
indicates |
T19105 |
15863-15876 |
RB |
denotes |
statistically |
T19106 |
15877-15888 |
JJ |
denotes |
significant |
T19107 |
15889-15900 |
NN |
denotes |
differences |
T19108 |
15901-15905 |
IN |
denotes |
from |
T19109 |
15906-15913 |
JJ |
denotes |
CCR5+/+ |
T19110 |
15914-15918 |
NN |
denotes |
mice |
T19111 |
15920-15925 |
NN |
denotes |
Scale |
T19112 |
15926-15929 |
NN |
denotes |
bar |
T19113 |
15930-15939 |
VB |
denotes |
indicates |
T19114 |
15940-15942 |
CD |
denotes |
50 |
T19115 |
15943-15945 |
NN |
denotes |
µm |
T19116 |
15947-15948 |
NN |
denotes |
F |
T19117 |
15949-15952 |
CC |
denotes |
and |
T19118 |
15953-15954 |
NN |
denotes |
G |
T19119 |
15954-15955 |
-COMMA- |
denotes |
, |
T19120 |
15956-15966 |
NN |
denotes |
Expression |
T19121 |
15967-15969 |
IN |
denotes |
of |
T19122 |
15970-15976 |
NN |
denotes |
IL-1Ra |
T19123 |
15977-15980 |
VB |
denotes |
was |
T19124 |
15981-15989 |
VB |
denotes |
analyzed |
T19125 |
15990-15992 |
IN |
denotes |
by |
T19126 |
15993-16000 |
JJ |
denotes |
western |
T19127 |
16001-16009 |
NN |
denotes |
blotting |
T19128 |
16010-16012 |
IN |
denotes |
in |
T19129 |
16013-16018 |
NN |
denotes |
tumor |
T19130 |
16019-16022 |
CC |
denotes |
and |
T19131 |
16023-16029 |
NN |
denotes |
spleen |
T19132 |
16030-16037 |
NN |
denotes |
tissues |
T19133 |
16039-16043 |
DT |
denotes |
Each |
T19134 |
16044-16048 |
NN |
denotes |
band |
T19135 |
16049-16051 |
VB |
denotes |
is |
T19136 |
16052-16066 |
JJ |
denotes |
representative |
T19137 |
16067-16069 |
IN |
denotes |
of |
T19138 |
16070-16075 |
CD |
denotes |
three |
T19139 |
16076-16087 |
JJ |
denotes |
independent |
T19140 |
16088-16100 |
JJ |
denotes |
experimental |
T19141 |
16101-16108 |
NN |
denotes |
results |
T19142 |
16110-16114 |
NN |
denotes |
Data |
T19143 |
16115-16118 |
VB |
denotes |
are |
T19144 |
16119-16124 |
NN |
denotes |
means |
T19145 |
16125-16126 |
VB |
denotes |
± |
T19146 |
16127-16131 |
NNP |
denotes |
S.D. |
T19147 |
16132-16134 |
IN |
denotes |
of |
T19148 |
16135-16140 |
CD |
denotes |
three |
T19149 |
16141-16153 |
JJ |
denotes |
experimental |
T19150 |
16154-16162 |
NN |
denotes |
animals. |
T19151 |
16163-16164 |
SYM |
denotes |
* |
T19152 |
16165-16174 |
VB |
denotes |
indicates |
T19153 |
16175-16186 |
JJ |
denotes |
significant |
T19154 |
16187-16197 |
NN |
denotes |
difference |
T19155 |
16198-16202 |
IN |
denotes |
from |
T19156 |
16203-16210 |
JJ |
denotes |
CCR5+/+ |
T19157 |
16211-16215 |
NN |
denotes |
mice |
T19158 |
16216-16217 |
-LRB- |
denotes |
( |
T19159 |
16217-16218 |
NN |
denotes |
p |
T19160 |
16218-16219 |
SYM |
denotes |
< |
T19161 |
16219-16223 |
CD |
denotes |
0.05 |
T19162 |
16223-16224 |
-RRB- |
denotes |
) |
T7434 |
16227-16236 |
NN |
denotes |
Induction |
T7435 |
16237-16239 |
IN |
denotes |
of |
T7436 |
16240-16243 |
NN |
denotes |
CD8 |
T7437 |
16244-16245 |
NN |
denotes |
T |
T7438 |
16246-16251 |
NN |
denotes |
cells |
T7439 |
16252-16255 |
CC |
denotes |
and |
T7440 |
16256-16258 |
NN |
denotes |
NK |
T7441 |
16259-16263 |
NNP |
denotes |
Cell |
T7442 |
16264-16276 |
NNP |
denotes |
Infiltration |
T7443 |
16277-16281 |
IN |
denotes |
into |
T7444 |
16282-16287 |
NN |
denotes |
Tumor |
T7445 |
16288-16291 |
CC |
denotes |
and |
T7446 |
16292-16298 |
NN |
denotes |
Spleen |
T7447 |
16299-16301 |
IN |
denotes |
of |
T7448 |
16302-16309 |
NN |
denotes |
CCR5−/− |
T7449 |
16310-16314 |
NN |
denotes |
Mice |
T7450 |
16315-16317 |
TO |
denotes |
To |
T7451 |
16318-16329 |
VB |
denotes |
investigate |
T7452 |
16330-16337 |
IN |
denotes |
whether |
T7453 |
16338-16341 |
DT |
denotes |
the |
T7454 |
16342-16352 |
NN |
denotes |
inhibition |
T7455 |
16353-16355 |
IN |
denotes |
of |
T7456 |
16356-16361 |
NN |
denotes |
tumor |
T7457 |
16362-16368 |
NN |
denotes |
growth |
T7458 |
16369-16371 |
IN |
denotes |
in |
T7459 |
16372-16379 |
NN |
denotes |
CCR5−/− |
T7460 |
16380-16384 |
NN |
denotes |
mice |
T7461 |
16385-16387 |
VB |
denotes |
is |
T7462 |
16388-16395 |
JJ |
denotes |
related |
T7463 |
16396-16398 |
TO |
denotes |
to |
T7464 |
16399-16413 |
JJ |
denotes |
tumor-specific |
T7465 |
16414-16420 |
JJ |
denotes |
immune |
T7466 |
16421-16430 |
NN |
denotes |
responses |
T7467 |
16430-16431 |
-COMMA- |
denotes |
, |
T7468 |
16432-16434 |
PRP |
denotes |
we |
T7469 |
16435-16443 |
VB |
denotes |
analyzed |
T7470 |
16444-16447 |
DT |
denotes |
the |
T7471 |
16448-16460 |
NN |
denotes |
distribution |
T7472 |
16461-16469 |
NN |
denotes |
patterns |
T7473 |
16470-16472 |
IN |
denotes |
of |
T7474 |
16473-16477 |
JJ |
denotes |
CD8+ |
T7475 |
16478-16487 |
JJ |
denotes |
cytotoxic |
T7476 |
16488-16489 |
NN |
denotes |
T |
T7477 |
16490-16494 |
NN |
denotes |
cell |
T7478 |
16495-16498 |
CC |
denotes |
and |
T7479 |
16499-16504 |
JJ |
denotes |
CD57+ |
T7480 |
16505-16512 |
JJ |
denotes |
Natural |
T7481 |
16513-16519 |
NN |
denotes |
Killer |
T7482 |
16520-16525 |
NN |
denotes |
cells |
T7483 |
16526-16528 |
IN |
denotes |
in |
T7484 |
16529-16534 |
NN |
denotes |
tumor |
T7485 |
16535-16538 |
CC |
denotes |
and |
T7486 |
16539-16545 |
NN |
denotes |
spleen |
T7487 |
16546-16553 |
NN |
denotes |
tissues |
T7488 |
16555-16557 |
IN |
denotes |
By |
T7489 |
16558-16566 |
VB |
denotes |
staining |
T7490 |
16567-16570 |
DT |
denotes |
the |
T7491 |
16571-16576 |
NN |
denotes |
tumor |
T7492 |
16577-16585 |
NN |
denotes |
sections |
T7493 |
16586-16590 |
IN |
denotes |
from |
T7494 |
16591-16598 |
NN |
denotes |
CCR5−/− |
T7495 |
16599-16603 |
NN |
denotes |
mice |
T7496 |
16603-16604 |
-COMMA- |
denotes |
, |
T7497 |
16605-16607 |
PRP |
denotes |
we |
T7498 |
16608-16613 |
VB |
denotes |
found |
T7499 |
16614-16618 |
IN |
denotes |
that |
T7500 |
16619-16624 |
EX |
denotes |
there |
T7501 |
16625-16628 |
VB |
denotes |
was |
T7502 |
16629-16630 |
DT |
denotes |
a |
T7503 |
16631-16642 |
JJ |
denotes |
significant |
T7504 |
16643-16649 |
NN |
denotes |
influx |
T7505 |
16650-16652 |
IN |
denotes |
of |
T7506 |
16653-16657 |
JJ |
denotes |
CD8+ |
T7507 |
16658-16663 |
NN |
denotes |
cells |
T7508 |
16664-16668 |
IN |
denotes |
into |
T7509 |
16669-16672 |
DT |
denotes |
the |
T7510 |
16673-16678 |
NN |
denotes |
tumor |
T7511 |
16678-16679 |
-COMMA- |
denotes |
, |
T7512 |
16680-16682 |
RB |
denotes |
as |
T7513 |
16683-16687 |
RB |
denotes |
well |
T7514 |
16688-16690 |
IN |
denotes |
as |
T7515 |
16691-16693 |
DT |
denotes |
an |
T7516 |
16694-16702 |
NN |
denotes |
increase |
T7517 |
16703-16705 |
IN |
denotes |
in |
T7518 |
16706-16709 |
DT |
denotes |
the |
T7519 |
16710-16716 |
NN |
denotes |
number |
T7520 |
16717-16719 |
IN |
denotes |
of |
T7521 |
16720-16732 |
VB |
denotes |
infiltrating |
T7522 |
16733-16735 |
NN |
denotes |
NK |
T7523 |
16736-16741 |
NN |
denotes |
cells |
T7524 |
16742-16743 |
-LRB- |
denotes |
( |
T7525 |
16743-16749 |
NN |
denotes |
Figure |
T7526 |
16750-16752 |
NN |
denotes |
5A |
T7527 |
16752-16753 |
-RRB- |
denotes |
) |
T7528 |
16755-16759 |
JJ |
denotes |
CD8+ |
T7529 |
16760-16761 |
NN |
denotes |
T |
T7530 |
16762-16767 |
NN |
denotes |
cells |
T7531 |
16768-16771 |
CC |
denotes |
and |
T7532 |
16772-16777 |
JJ |
denotes |
CD57+ |
T7533 |
16778-16780 |
NN |
denotes |
NK |
T7534 |
16781-16786 |
NN |
denotes |
cells |
T7535 |
16787-16791 |
VB |
denotes |
were |
T7536 |
16792-16798 |
VB |
denotes |
spread |
T7537 |
16799-16808 |
RB |
denotes |
diffusely |
T7538 |
16809-16819 |
IN |
denotes |
throughout |
T7539 |
16820-16823 |
DT |
denotes |
the |
T7540 |
16824-16830 |
JJ |
denotes |
entire |
T7541 |
16831-16839 |
NN |
denotes |
sections |
T7542 |
16841-16843 |
TO |
denotes |
To |
T7543 |
16844-16851 |
RB |
denotes |
further |
T7544 |
16852-16863 |
VB |
denotes |
investigate |
T7545 |
16864-16867 |
DT |
denotes |
the |
T7546 |
16868-16879 |
NN |
denotes |
differences |
T7547 |
16880-16882 |
IN |
denotes |
in |
T7548 |
16883-16886 |
DT |
denotes |
the |
T7549 |
16887-16894 |
NN |
denotes |
numbers |
T7550 |
16895-16897 |
IN |
denotes |
of |
T7551 |
16898-16902 |
JJ |
denotes |
CD8+ |
T7552 |
16903-16904 |
NN |
denotes |
T |
T7553 |
16905-16910 |
NN |
denotes |
cells |
T7554 |
16911-16914 |
CC |
denotes |
and |
T7555 |
16915-16920 |
JJ |
denotes |
CD57+ |
T7556 |
16921-16923 |
NN |
denotes |
NK |
T7557 |
16924-16929 |
NN |
denotes |
cells |
T7558 |
16930-16937 |
IN |
denotes |
between |
T7559 |
16938-16945 |
JJ |
denotes |
CCR5+/+ |
T7560 |
16946-16950 |
NN |
denotes |
mice |
T7561 |
16951-16954 |
CC |
denotes |
and |
T7562 |
16955-16962 |
NN |
denotes |
CCR5−/− |
T7563 |
16963-16967 |
NN |
denotes |
mice |
T7564 |
16968-16970 |
IN |
denotes |
in |
T7565 |
16971-16987 |
JJ |
denotes |
immunity-related |
T7566 |
16988-16993 |
NN |
denotes |
organ |
T7567 |
16993-16994 |
-COMMA- |
denotes |
, |
T7568 |
16995-16997 |
PRP |
denotes |
we |
T7569 |
16998-17002 |
RB |
denotes |
also |
T7570 |
17003-17011 |
VB |
denotes |
analyzed |
T7571 |
17012-17015 |
DT |
denotes |
the |
T7572 |
17016-17019 |
NN |
denotes |
CD8 |
T7573 |
17020-17023 |
CC |
denotes |
and |
T7574 |
17024-17028 |
NN |
denotes |
CD57 |
T7575 |
17029-17037 |
JJ |
denotes |
reactive |
T7576 |
17038-17042 |
NN |
denotes |
cell |
T7577 |
17043-17049 |
NN |
denotes |
number |
T7578 |
17050-17052 |
IN |
denotes |
in |
T7579 |
17053-17059 |
NN |
denotes |
spleen |
T7580 |
17060-17067 |
NN |
denotes |
tissues |
T7581 |
17069-17072 |
DT |
denotes |
The |
T7582 |
17073-17079 |
NN |
denotes |
number |
T7583 |
17080-17082 |
IN |
denotes |
of |
T7584 |
17083-17087 |
JJ |
denotes |
CD8+ |
T7585 |
17088-17089 |
NN |
denotes |
T |
T7586 |
17090-17095 |
NN |
denotes |
cells |
T7587 |
17096-17099 |
CC |
denotes |
and |
T7588 |
17100-17105 |
JJ |
denotes |
CD57+ |
T7589 |
17106-17108 |
NN |
denotes |
NK |
T7590 |
17109-17114 |
NN |
denotes |
cells |
T7591 |
17115-17119 |
VB |
denotes |
were |
T7592 |
17120-17126 |
JJ |
denotes |
higher |
T7593 |
17127-17129 |
IN |
denotes |
in |
T7594 |
17130-17133 |
DT |
denotes |
the |
T7595 |
17134-17140 |
NN |
denotes |
spleen |
T7596 |
17141-17143 |
IN |
denotes |
of |
T7597 |
17144-17147 |
DT |
denotes |
the |
T7598 |
17148-17155 |
NN |
denotes |
CCR5−/− |
T7599 |
17156-17160 |
NN |
denotes |
mice |
T7600 |
17161-17165 |
IN |
denotes |
than |
T7601 |
17166-17168 |
IN |
denotes |
in |
T7602 |
17169-17172 |
DT |
denotes |
the |
T7603 |
17173-17179 |
NN |
denotes |
spleen |
T7604 |
17180-17182 |
IN |
denotes |
of |
T7605 |
17183-17186 |
DT |
denotes |
the |
T7606 |
17187-17194 |
JJ |
denotes |
CCR5+/+ |
T7607 |
17195-17199 |
NN |
denotes |
mice |
T7608 |
17200-17201 |
-LRB- |
denotes |
( |
T7609 |
17201-17207 |
NN |
denotes |
Figure |
T7610 |
17208-17210 |
NN |
denotes |
5B |
T7611 |
17210-17211 |
-RRB- |
denotes |
) |
T7612 |
17213-17218 |
DT |
denotes |
These |
T7613 |
17219-17223 |
NN |
denotes |
data |
T7614 |
17224-17231 |
VB |
denotes |
suggest |
T7615 |
17232-17236 |
IN |
denotes |
that |
T7616 |
17237-17239 |
IN |
denotes |
by |
T7617 |
17240-17249 |
VB |
denotes |
promoting |
T7618 |
17250-17253 |
DT |
denotes |
the |
T7619 |
17254-17266 |
NN |
denotes |
infiltration |
T7620 |
17267-17269 |
IN |
denotes |
of |
T7621 |
17270-17273 |
NN |
denotes |
CD8 |
T7622 |
17274-17275 |
NN |
denotes |
T |
T7623 |
17276-17281 |
NN |
denotes |
cells |
T7624 |
17282-17285 |
CC |
denotes |
and |
T7625 |
17286-17288 |
NN |
denotes |
NK |
T7626 |
17289-17294 |
NN |
denotes |
cells |
T7627 |
17294-17295 |
-COMMA- |
denotes |
, |
T7628 |
17296-17301 |
WDT |
denotes |
which |
T7629 |
17302-17305 |
VB |
denotes |
are |
T7630 |
17306-17312 |
JJ |
denotes |
potent |
T7631 |
17313-17322 |
JJ |
denotes |
cytotoxic |
T7632 |
17323-17332 |
NN |
denotes |
effectors |
T7633 |
17333-17336 |
IN |
denotes |
for |
T7634 |
17337-17343 |
NN |
denotes |
tumors |
T7635 |
17343-17344 |
-COMMA- |
denotes |
, |
T7636 |
17345-17350 |
MD |
denotes |
could |
T7637 |
17351-17355 |
VB |
denotes |
play |
T7638 |
17356-17357 |
DT |
denotes |
a |
T7639 |
17358-17362 |
NN |
denotes |
role |
T7640 |
17363-17365 |
IN |
denotes |
in |
T7641 |
17366-17368 |
DT |
denotes |
an |
T7642 |
17369-17379 |
JJ |
denotes |
anti-tumor |
T7643 |
17380-17386 |
NN |
denotes |
effect |
T7644 |
17387-17389 |
IN |
denotes |
in |
T7645 |
17390-17397 |
NN |
denotes |
CCR5−/− |
T7646 |
17398-17402 |
NN |
denotes |
mice |
T19603 |
17448-17457 |
NN |
denotes |
Induction |
T19604 |
17458-17460 |
IN |
denotes |
of |
T19605 |
17461-17464 |
DT |
denotes |
the |
T19606 |
17465-17477 |
NN |
denotes |
infiltration |
T19607 |
17478-17480 |
IN |
denotes |
of |
T19608 |
17481-17485 |
JJ |
denotes |
CD8+ |
T19609 |
17486-17487 |
NN |
denotes |
T |
T19610 |
17488-17493 |
NN |
denotes |
cells |
T19611 |
17494-17497 |
CC |
denotes |
and |
T19612 |
17498-17500 |
NN |
denotes |
NK |
T19613 |
17501-17506 |
NN |
denotes |
cells |
T19614 |
17507-17511 |
IN |
denotes |
into |
T19615 |
17512-17517 |
NN |
denotes |
tumor |
T19616 |
17517-17518 |
-COMMA- |
denotes |
, |
T19617 |
17519-17522 |
CC |
denotes |
and |
T19618 |
17523-17531 |
NN |
denotes |
increase |
T19619 |
17532-17534 |
IN |
denotes |
in |
T19620 |
17535-17541 |
NN |
denotes |
spleen |
T19621 |
17542-17544 |
IN |
denotes |
of |
T19622 |
17545-17552 |
NN |
denotes |
CCR5−/− |
T19623 |
17553-17557 |
NN |
denotes |
mice |
T19624 |
17559-17560 |
DT |
denotes |
A |
T19625 |
17561-17564 |
CC |
denotes |
and |
T19626 |
17565-17566 |
NN |
denotes |
B |
T19627 |
17566-17567 |
-COMMA- |
denotes |
, |
T19628 |
17568-17587 |
NN |
denotes |
Immunolfluorescence |
T19629 |
17588-17596 |
NN |
denotes |
analysis |
T19630 |
17597-17600 |
VB |
denotes |
was |
T19631 |
17601-17605 |
VB |
denotes |
used |
T19632 |
17606-17608 |
TO |
denotes |
to |
T19633 |
17609-17618 |
VB |
denotes |
determine |
T19634 |
17619-17622 |
DT |
denotes |
the |
T19635 |
17623-17633 |
NN |
denotes |
expression |
T19636 |
17634-17640 |
NN |
denotes |
levels |
T19637 |
17641-17643 |
IN |
denotes |
of |
T19638 |
17644-17647 |
NN |
denotes |
CD8 |
T19639 |
17648-17649 |
-LRB- |
denotes |
( |
T19640 |
17649-17653 |
JJ |
denotes |
CD8+ |
T19641 |
17654-17663 |
JJ |
denotes |
cytotoxic |
T19642 |
17664-17670 |
NN |
denotes |
T-cell |
T19643 |
17671-17678 |
NN |
denotes |
surface |
T19644 |
17679-17685 |
NN |
denotes |
marker |
T19645 |
17685-17686 |
-RRB- |
denotes |
) |
T19646 |
17687-17690 |
CC |
denotes |
and |
T19647 |
17691-17695 |
NN |
denotes |
CD57 |
T19648 |
17696-17697 |
-LRB- |
denotes |
( |
T19649 |
17697-17699 |
NN |
denotes |
NK |
T19650 |
17700-17704 |
NN |
denotes |
cell |
T19651 |
17705-17711 |
NN |
denotes |
marker |
T19652 |
17711-17712 |
-RRB- |
denotes |
) |
T19653 |
17713-17715 |
IN |
denotes |
in |
T19654 |
17716-17721 |
NN |
denotes |
tumor |
T19655 |
17722-17725 |
CC |
denotes |
and |
T19656 |
17726-17732 |
NN |
denotes |
spleen |
T19657 |
17733-17741 |
NN |
denotes |
sections |
T19658 |
17743-17746 |
DT |
denotes |
The |
T19659 |
17747-17753 |
NN |
denotes |
images |
T19660 |
17754-17759 |
VB |
denotes |
shown |
T19661 |
17760-17763 |
VB |
denotes |
are |
T19662 |
17764-17778 |
JJ |
denotes |
representative |
T19663 |
17779-17781 |
IN |
denotes |
of |
T19664 |
17782-17787 |
CD |
denotes |
three |
T19665 |
17788-17796 |
JJ |
denotes |
separate |
T19666 |
17797-17808 |
NN |
denotes |
experiments |
T19667 |
17809-17818 |
VB |
denotes |
performed |
T19668 |
17819-17821 |
IN |
denotes |
in |
T19669 |
17822-17832 |
NN |
denotes |
triplicate |
T19670 |
17834-17839 |
NN |
denotes |
Scale |
T19671 |
17840-17844 |
NN |
denotes |
bars |
T19672 |
17845-17853 |
VB |
denotes |
indicate |
T19673 |
17854-17856 |
CD |
denotes |
50 |
T19674 |
17857-17859 |
NN |
denotes |
µm |
T19675 |
17860-17861 |
-LRB- |
denotes |
( |
T19676 |
17861-17862 |
NN |
denotes |
A |
T19677 |
17862-17863 |
-RRB- |
denotes |
) |
T19678 |
17864-17867 |
CC |
denotes |
and |
T19679 |
17868-17871 |
CD |
denotes |
100 |
T19680 |
17872-17874 |
NN |
denotes |
µm |
T19681 |
17875-17876 |
-LRB- |
denotes |
( |
T19682 |
17876-17877 |
NN |
denotes |
B |
T19683 |
17877-17878 |
-RRB- |
denotes |
) |
T19684 |
17880-17881 |
NN |
denotes |
C |
T19685 |
17882-17885 |
CC |
denotes |
and |
T19686 |
17886-17887 |
NN |
denotes |
D |
T19687 |
17887-17888 |
-COMMA- |
denotes |
, |
T19688 |
17889-17897 |
NN |
denotes |
Analysis |
T19689 |
17898-17900 |
IN |
denotes |
of |
T19690 |
17901-17911 |
NN |
denotes |
lymphocyte |
T19691 |
17912-17922 |
NN |
denotes |
phenotypes |
T19692 |
17924-17927 |
DT |
denotes |
The |
T19693 |
17928-17933 |
NN |
denotes |
tumor |
T19694 |
17934-17937 |
CC |
denotes |
and |
T19695 |
17938-17944 |
NN |
denotes |
spleen |
T19696 |
17945-17952 |
NN |
denotes |
tissues |
T19697 |
17953-17957 |
VB |
denotes |
were |
T19698 |
17958-17967 |
VB |
denotes |
separated |
T19699 |
17968-17970 |
IN |
denotes |
at |
T19700 |
17971-17976 |
NN |
denotes |
study |
T19701 |
17977-17988 |
NN |
denotes |
termination |
T19702 |
17989-17990 |
-LRB- |
denotes |
( |
T19703 |
17990-17993 |
NN |
denotes |
Day |
T19704 |
17994-17996 |
CD |
denotes |
31 |
T19705 |
17996-17997 |
-RRB- |
denotes |
) |
T19706 |
17999-18003 |
NN |
denotes |
Flow |
T19707 |
18004-18013 |
NN |
denotes |
cytometry |
T19708 |
18014-18022 |
NN |
denotes |
analysis |
T19709 |
18023-18026 |
VB |
denotes |
was |
T19710 |
18027-18036 |
VB |
denotes |
performed |
T19711 |
18037-18042 |
VB |
denotes |
using |
T19712 |
18043-18051 |
NN |
denotes |
FACSAria |
T19713 |
18052-18056 |
NN |
denotes |
flow |
T19714 |
18057-18066 |
NN |
denotes |
cytometry |
T19715 |
18066-18067 |
-COMMA- |
denotes |
, |
T19716 |
18068-18071 |
CC |
denotes |
and |
T19717 |
18072-18081 |
VB |
denotes |
represent |
T19718 |
18082-18086 |
NN |
denotes |
data |
T19719 |
18087-18091 |
VB |
denotes |
were |
T19720 |
18092-18097 |
VB |
denotes |
shown |
T19721 |
18099-18103 |
NN |
denotes |
Data |
T19722 |
18104-18107 |
VB |
denotes |
are |
T19723 |
18108-18113 |
NN |
denotes |
means |
T19724 |
18114-18115 |
VB |
denotes |
± |
T19725 |
18116-18120 |
NNP |
denotes |
S.D. |
T19726 |
18121-18123 |
IN |
denotes |
of |
T19727 |
18124-18128 |
CD |
denotes |
four |
T19728 |
18129-18141 |
JJ |
denotes |
experimental |
T19729 |
18142-18149 |
NN |
denotes |
animals |
T7647 |
18151-18153 |
TO |
denotes |
To |
T7648 |
18154-18161 |
VB |
denotes |
analyze |
T7649 |
18162-18165 |
DT |
denotes |
the |
T7650 |
18166-18170 |
NN |
denotes |
cell |
T7651 |
18171-18180 |
NN |
denotes |
phenotype |
T7652 |
18181-18187 |
NN |
denotes |
change |
T7653 |
18188-18190 |
IN |
denotes |
in |
T7654 |
18191-18198 |
NN |
denotes |
CCR5−/− |
T7655 |
18199-18203 |
NN |
denotes |
mice |
T7656 |
18204-18207 |
CC |
denotes |
and |
T7657 |
18208-18215 |
JJ |
denotes |
CCR5+/+ |
T7658 |
18216-18220 |
NN |
denotes |
mice |
T7659 |
18221-18223 |
IN |
denotes |
by |
T7660 |
18224-18235 |
NN |
denotes |
inoculation |
T7661 |
18236-18238 |
IN |
denotes |
of |
T7662 |
18239-18242 |
DT |
denotes |
the |
T7663 |
18243-18251 |
NN |
denotes |
melanoma |
T7664 |
18252-18256 |
NN |
denotes |
cell |
T7665 |
18256-18257 |
-COMMA- |
denotes |
, |
T7666 |
18258-18269 |
NN |
denotes |
lymphocytes |
T7667 |
18270-18274 |
VB |
denotes |
were |
T7668 |
18275-18283 |
VB |
denotes |
isolated |
T7669 |
18284-18288 |
IN |
denotes |
from |
T7670 |
18289-18292 |
DT |
denotes |
the |
T7671 |
18293-18298 |
NN |
denotes |
tumor |
T7672 |
18299-18302 |
CC |
denotes |
and |
T7673 |
18303-18309 |
NN |
denotes |
spleen |
T7674 |
18310-18317 |
NN |
denotes |
tissues |
T7675 |
18319-18322 |
DT |
denotes |
The |
T7676 |
18323-18324 |
NN |
denotes |
B |
T7677 |
18324-18325 |
-COMMA- |
denotes |
, |
T7678 |
18326-18329 |
NN |
denotes |
CD3 |
T7679 |
18330-18331 |
NNP |
denotes |
T |
T7680 |
18331-18332 |
-COMMA- |
denotes |
, |
T7681 |
18333-18336 |
NN |
denotes |
CD4 |
T7682 |
18337-18338 |
NN |
denotes |
T |
T7683 |
18338-18339 |
-COMMA- |
denotes |
, |
T7684 |
18340-18342 |
NN |
denotes |
CD |
T7685 |
18343-18344 |
CD |
denotes |
8 |
T7686 |
18345-18346 |
NN |
denotes |
T |
T7687 |
18347-18350 |
CC |
denotes |
and |
T7688 |
18351-18353 |
NN |
denotes |
NK |
T7689 |
18354-18358 |
NN |
denotes |
cell |
T7690 |
18359-18366 |
NN |
denotes |
portion |
T7691 |
18367-18369 |
IN |
denotes |
of |
T7692 |
18370-18377 |
NN |
denotes |
CCR5−/− |
T7693 |
18378-18382 |
NN |
denotes |
mice |
T7694 |
18383-18388 |
NN |
denotes |
tumor |
T7695 |
18389-18395 |
NN |
denotes |
tissue |
T7696 |
18396-18400 |
VB |
denotes |
were |
T7697 |
18401-18404 |
CD |
denotes |
7.2 |
T7698 |
18404-18405 |
NN |
denotes |
% |
T7699 |
18405-18406 |
-COMMA- |
denotes |
, |
T7700 |
18407-18411 |
CD |
denotes |
48.2 |
T7701 |
18411-18412 |
NN |
denotes |
% |
T7702 |
18412-18413 |
-COMMA- |
denotes |
, |
T7703 |
18414-18418 |
CD |
denotes |
16.9 |
T7704 |
18418-18419 |
NN |
denotes |
% |
T7705 |
18419-18420 |
-COMMA- |
denotes |
, |
T7706 |
18421-18425 |
CD |
denotes |
32.1 |
T7707 |
18425-18426 |
NN |
denotes |
% |
T7708 |
18427-18430 |
CC |
denotes |
and |
T7709 |
18431-18434 |
CD |
denotes |
7.8 |
T7710 |
18434-18435 |
NN |
denotes |
% |
T7711 |
18435-18436 |
-COMMA- |
denotes |
, |
T7712 |
18437-18449 |
RB |
denotes |
respectively |
T7713 |
18449-18450 |
-COMMA- |
denotes |
, |
T7714 |
18451-18459 |
VB |
denotes |
compared |
T7715 |
18460-18462 |
TO |
denotes |
to |
T7716 |
18463-18466 |
CD |
denotes |
2.9 |
T7717 |
18466-18467 |
NN |
denotes |
% |
T7718 |
18467-18468 |
-COMMA- |
denotes |
, |
T7719 |
18469-18473 |
CD |
denotes |
11.1 |
T7720 |
18473-18474 |
NN |
denotes |
% |
T7721 |
18474-18475 |
-COMMA- |
denotes |
, |
T7722 |
18476-18479 |
CD |
denotes |
2.3 |
T7723 |
18479-18480 |
NN |
denotes |
% |
T7724 |
18480-18481 |
-COMMA- |
denotes |
, |
T7725 |
18482-18485 |
CD |
denotes |
0.6 |
T7726 |
18485-18486 |
NN |
denotes |
% |
T7727 |
18487-18490 |
CC |
denotes |
and |
T7728 |
18491-18494 |
CD |
denotes |
3.1 |
T7729 |
18494-18495 |
NN |
denotes |
% |
T7730 |
18496-18498 |
IN |
denotes |
of |
T7731 |
18499-18506 |
JJ |
denotes |
CCR5+/+ |
T7732 |
18507-18511 |
NN |
denotes |
mice |
T7733 |
18512-18513 |
-LRB- |
denotes |
( |
T7734 |
18513-18519 |
NN |
denotes |
Figure |
T7735 |
18520-18522 |
NN |
denotes |
5C |
T7736 |
18522-18523 |
-RRB- |
denotes |
) |
T7737 |
18525-18528 |
DT |
denotes |
The |
T7738 |
18529-18540 |
NN |
denotes |
lymphocytes |
T7739 |
18541-18545 |
WDT |
denotes |
that |
T7740 |
18546-18557 |
VB |
denotes |
infiltrated |
T7741 |
18558-18561 |
DT |
denotes |
the |
T7742 |
18562-18567 |
NN |
denotes |
tumor |
T7743 |
18568-18574 |
NN |
denotes |
tissue |
T7744 |
18575-18577 |
IN |
denotes |
of |
T7745 |
18578-18581 |
DT |
denotes |
the |
T7746 |
18582-18589 |
NN |
denotes |
CCR5−/− |
T7747 |
18590-18594 |
NN |
denotes |
mice |
T7748 |
18595-18599 |
RB |
denotes |
also |
T7749 |
18600-18603 |
VB |
denotes |
had |
T7750 |
18604-18610 |
JJ |
denotes |
higher |
T7751 |
18611-18617 |
NN |
denotes |
levels |
T7752 |
18618-18620 |
IN |
denotes |
of |
T7753 |
18621-18625 |
NN |
denotes |
CD19 |
T7754 |
18625-18626 |
-COMMA- |
denotes |
, |
T7755 |
18627-18630 |
NN |
denotes |
CD3 |
T7756 |
18630-18631 |
-COMMA- |
denotes |
, |
T7757 |
18632-18635 |
NN |
denotes |
CD4 |
T7758 |
18635-18636 |
-COMMA- |
denotes |
, |
T7759 |
18637-18640 |
NN |
denotes |
CD8 |
T7760 |
18641-18644 |
CC |
denotes |
and |
T7761 |
18645-18649 |
NN |
denotes |
CD57 |
T7762 |
18650-18654 |
WRB |
denotes |
when |
T7763 |
18655-18663 |
VB |
denotes |
compared |
T7764 |
18664-18666 |
TO |
denotes |
to |
T7765 |
18667-18670 |
DT |
denotes |
the |
T7766 |
18671-18678 |
NN |
denotes |
CCR5+/+ |
T7767 |
18679-18683 |
NN |
denotes |
mice |
T7768 |
18685-18688 |
DT |
denotes |
The |
T7769 |
18689-18690 |
NN |
denotes |
B |
T7770 |
18690-18691 |
-COMMA- |
denotes |
, |
T7771 |
18692-18695 |
NN |
denotes |
CD3 |
T7772 |
18696-18697 |
NNP |
denotes |
T |
T7773 |
18697-18698 |
-COMMA- |
denotes |
, |
T7774 |
18699-18702 |
NN |
denotes |
CD4 |
T7775 |
18703-18704 |
NN |
denotes |
T |
T7776 |
18704-18705 |
-COMMA- |
denotes |
, |
T7777 |
18706-18708 |
NN |
denotes |
CD |
T7778 |
18709-18710 |
CD |
denotes |
8 |
T7779 |
18711-18712 |
NN |
denotes |
T |
T7780 |
18713-18716 |
CC |
denotes |
and |
T7781 |
18717-18719 |
NN |
denotes |
NK |
T7782 |
18720-18724 |
NN |
denotes |
cell |
T7783 |
18725-18732 |
NN |
denotes |
portion |
T7784 |
18733-18735 |
IN |
denotes |
of |
T7785 |
18736-18739 |
DT |
denotes |
the |
T7786 |
18740-18747 |
NN |
denotes |
CCR5−/− |
T7787 |
18748-18752 |
NN |
denotes |
mice |
T7788 |
18753-18759 |
NN |
denotes |
spleen |
T7789 |
18760-18764 |
VB |
denotes |
were |
T7790 |
18765-18769 |
CD |
denotes |
61.3 |
T7791 |
18769-18770 |
NN |
denotes |
% |
T7792 |
18770-18771 |
-COMMA- |
denotes |
, |
T7793 |
18772-18776 |
CD |
denotes |
33.4 |
T7794 |
18776-18777 |
NN |
denotes |
% |
T7795 |
18777-18778 |
-COMMA- |
denotes |
, |
T7796 |
18779-18783 |
CD |
denotes |
17.6 |
T7797 |
18783-18784 |
NN |
denotes |
% |
T7798 |
18784-18785 |
-COMMA- |
denotes |
, |
T7799 |
18786-18789 |
CD |
denotes |
9.2 |
T7800 |
18789-18790 |
NN |
denotes |
% |
T7801 |
18791-18794 |
CC |
denotes |
and |
T7802 |
18795-18798 |
CD |
denotes |
0.6 |
T7803 |
18798-18799 |
NN |
denotes |
% |
T7804 |
18799-18800 |
-COMMA- |
denotes |
, |
T7805 |
18801-18813 |
RB |
denotes |
respectively |
T7806 |
18814-18822 |
VB |
denotes |
compared |
T7807 |
18823-18825 |
TO |
denotes |
to |
T7808 |
18826-18830 |
CD |
denotes |
38.3 |
T7809 |
18830-18831 |
NN |
denotes |
% |
T7810 |
18831-18832 |
-COMMA- |
denotes |
, |
T7811 |
18833-18836 |
CD |
denotes |
5.9 |
T7812 |
18836-18837 |
NN |
denotes |
% |
T7813 |
18837-18838 |
-COMMA- |
denotes |
, |
T7814 |
18839-18842 |
CD |
denotes |
4.0 |
T7815 |
18842-18843 |
NN |
denotes |
% |
T7816 |
18843-18844 |
-COMMA- |
denotes |
, |
T7817 |
18845-18848 |
CD |
denotes |
1.0 |
T7818 |
18848-18849 |
NN |
denotes |
% |
T7819 |
18850-18853 |
CC |
denotes |
and |
T7820 |
18854-18857 |
CD |
denotes |
3.9 |
T7821 |
18857-18858 |
NN |
denotes |
% |
T7822 |
18859-18861 |
IN |
denotes |
of |
T7823 |
18862-18865 |
DT |
denotes |
the |
T7824 |
18866-18873 |
JJ |
denotes |
CCR5+/+ |
T7825 |
18874-18878 |
NN |
denotes |
mice |
T7826 |
18879-18880 |
-LRB- |
denotes |
( |
T7827 |
18880-18886 |
NN |
denotes |
Figure |
T7828 |
18887-18889 |
NN |
denotes |
5D |
T7829 |
18889-18890 |
-RRB- |
denotes |
) |
T7830 |
18892-18897 |
DT |
denotes |
These |
T7831 |
18898-18902 |
NN |
denotes |
data |
T7832 |
18903-18910 |
VB |
denotes |
suggest |
T7833 |
18911-18915 |
IN |
denotes |
that |
T7834 |
18916-18918 |
IN |
denotes |
by |
T7835 |
18919-18928 |
VB |
denotes |
promoting |
T7836 |
18929-18932 |
DT |
denotes |
the |
T7837 |
18933-18945 |
NN |
denotes |
infiltration |
T7838 |
18946-18948 |
IN |
denotes |
of |
T7839 |
18949-18952 |
NN |
denotes |
CD8 |
T7840 |
18953-18954 |
NN |
denotes |
T |
T7841 |
18955-18960 |
NN |
denotes |
cells |
T7842 |
18961-18964 |
CC |
denotes |
and |
T7843 |
18965-18967 |
NN |
denotes |
NK |
T7844 |
18968-18973 |
NN |
denotes |
cells |
T7845 |
18973-18974 |
-COMMA- |
denotes |
, |
T7846 |
18975-18980 |
WDT |
denotes |
which |
T7847 |
18981-18984 |
VB |
denotes |
are |
T7848 |
18985-18991 |
JJ |
denotes |
potent |
T7849 |
18992-19001 |
JJ |
denotes |
cytotoxic |
T7850 |
19002-19011 |
NN |
denotes |
effectors |
T7851 |
19012-19015 |
IN |
denotes |
for |
T7852 |
19016-19022 |
NN |
denotes |
tumors |
T7853 |
19022-19023 |
-COMMA- |
denotes |
, |
T7854 |
19024-19029 |
MD |
denotes |
could |
T7855 |
19030-19034 |
VB |
denotes |
play |
T7856 |
19035-19036 |
DT |
denotes |
a |
T7857 |
19037-19041 |
NN |
denotes |
role |
T7858 |
19042-19044 |
IN |
denotes |
in |
T7859 |
19045-19048 |
DT |
denotes |
the |
T7860 |
19049-19059 |
NN |
denotes |
inhibition |
T7861 |
19060-19062 |
IN |
denotes |
of |
T7862 |
19063-19068 |
NN |
denotes |
tumor |
T7863 |
19069-19075 |
NN |
denotes |
growth |
T7864 |
19076-19078 |
IN |
denotes |
in |
T7865 |
19079-19086 |
NN |
denotes |
CCR5−/− |
T7866 |
19087-19091 |
NN |
denotes |
mice |
T9412 |
19105-19107 |
IN |
denotes |
In |
T9413 |
19108-19111 |
DT |
denotes |
the |
T9414 |
19112-19119 |
JJ |
denotes |
present |
T9415 |
19120-19125 |
NN |
denotes |
study |
T9416 |
19125-19126 |
-COMMA- |
denotes |
, |
T9417 |
19127-19129 |
PRP |
denotes |
we |
T9418 |
19130-19135 |
VB |
denotes |
found |
T9419 |
19136-19140 |
IN |
denotes |
that |
T9420 |
19141-19146 |
NN |
denotes |
tumor |
T9421 |
19147-19153 |
NN |
denotes |
weight |
T9422 |
19154-19157 |
CC |
denotes |
and |
T9423 |
19158-19164 |
NN |
denotes |
volume |
T9424 |
19165-19169 |
VB |
denotes |
were |
T9425 |
19170-19174 |
RB |
denotes |
much |
T9426 |
19175-19182 |
JJ |
denotes |
smaller |
T9427 |
19183-19185 |
IN |
denotes |
in |
T9428 |
19186-19189 |
DT |
denotes |
the |
T9429 |
19190-19197 |
NN |
denotes |
CCR5−/− |
T9430 |
19198-19202 |
NN |
denotes |
mice |
T9431 |
19203-19211 |
VB |
denotes |
compared |
T9432 |
19212-19214 |
TO |
denotes |
to |
T9433 |
19215-19218 |
DT |
denotes |
the |
T9434 |
19219-19226 |
JJ |
denotes |
CCR5+/+ |
T9435 |
19227-19231 |
NN |
denotes |
mice |
T9436 |
19232-19242 |
VB |
denotes |
inoculated |
T9437 |
19243-19247 |
IN |
denotes |
with |
T9438 |
19248-19251 |
NN |
denotes |
B16 |
T9439 |
19252-19260 |
NN |
denotes |
melanoma |
T9440 |
19261-19266 |
NN |
denotes |
cells |
T9441 |
19267-19268 |
-LRB- |
denotes |
( |
T9442 |
19268-19274 |
NN |
denotes |
Figure |
T9443 |
19275-19277 |
NN |
denotes |
1A |
T9444 |
19278-19281 |
CC |
denotes |
and |
T9445 |
19282-19284 |
NN |
denotes |
1B |
T9446 |
19284-19285 |
-RRB- |
denotes |
) |
T9447 |
19287-19290 |
DT |
denotes |
The |
T9448 |
19291-19296 |
NN |
denotes |
tumor |
T9449 |
19297-19303 |
NN |
denotes |
growth |
T9450 |
19304-19314 |
NN |
denotes |
inhibition |
T9451 |
19315-19317 |
IN |
denotes |
in |
T9452 |
19318-19321 |
DT |
denotes |
the |
T9453 |
19322-19329 |
NN |
denotes |
CCR5−/− |
T9454 |
19330-19334 |
NN |
denotes |
mice |
T9455 |
19335-19338 |
VB |
denotes |
was |
T9456 |
19339-19349 |
VB |
denotes |
associated |
T9457 |
19350-19354 |
IN |
denotes |
with |
T9458 |
19355-19358 |
DT |
denotes |
the |
T9459 |
19359-19369 |
NN |
denotes |
inhibition |
T9460 |
19370-19372 |
IN |
denotes |
of |
T9461 |
19373-19387 |
RB |
denotes |
constitutively |
T9462 |
19388-19397 |
VB |
denotes |
activated |
T9463 |
19398-19403 |
NN |
denotes |
NF-κB |
T9464 |
19404-19407 |
CC |
denotes |
and |
T9465 |
19408-19417 |
NN |
denotes |
elevation |
T9466 |
19418-19420 |
IN |
denotes |
of |
T9467 |
19421-19427 |
NN |
denotes |
IL-1Ra |
T9468 |
19428-19430 |
IN |
denotes |
in |
T9469 |
19431-19434 |
DT |
denotes |
the |
T9470 |
19435-19440 |
NN |
denotes |
tumor |
T9471 |
19441-19447 |
NN |
denotes |
tissue |
T9472 |
19449-19453 |
DT |
denotes |
This |
T9473 |
19454-19464 |
JJ |
denotes |
anti-tumor |
T9474 |
19465-19473 |
NN |
denotes |
activity |
T9475 |
19474-19477 |
VB |
denotes |
was |
T9476 |
19478-19482 |
RB |
denotes |
also |
T9477 |
19483-19493 |
VB |
denotes |
associated |
T9478 |
19494-19498 |
IN |
denotes |
with |
T9479 |
19499-19508 |
VB |
denotes |
decreased |
T9480 |
19509-19519 |
NN |
denotes |
expression |
T9481 |
19520-19522 |
IN |
denotes |
of |
T9482 |
19523-19528 |
NN |
denotes |
NF-κB |
T9483 |
19529-19535 |
NN |
denotes |
target |
T9484 |
19536-19550 |
JJ |
denotes |
anti-apoptotic |
T9485 |
19550-19551 |
-COMMA- |
denotes |
, |
T9486 |
19552-19556 |
NN |
denotes |
cell |
T9487 |
19557-19570 |
JJ |
denotes |
proliferative |
T9488 |
19570-19571 |
-COMMA- |
denotes |
, |
T9489 |
19572-19575 |
CC |
denotes |
and |
T9490 |
19576-19581 |
NN |
denotes |
tumor |
T9491 |
19582-19591 |
VB |
denotes |
promoting |
T9492 |
19592-19597 |
NN |
denotes |
genes |
T9493 |
19598-19599 |
-LRB- |
denotes |
( |
T9494 |
19599-19604 |
NN |
denotes |
Bcl-2 |
T9495 |
19605-19608 |
CC |
denotes |
and |
T9496 |
19609-19615 |
NN |
denotes |
C-IAP1 |
T9497 |
19615-19616 |
-RRB- |
denotes |
) |
T9498 |
19617-19620 |
CC |
denotes |
but |
T9499 |
19621-19625 |
IN |
denotes |
with |
T9500 |
19626-19635 |
VB |
denotes |
increased |
T9501 |
19636-19646 |
NN |
denotes |
expression |
T9502 |
19647-19649 |
IN |
denotes |
of |
T9503 |
19650-19655 |
PRP-DOLLAR- |
denotes |
their |
T9504 |
19656-19662 |
NN |
denotes |
target |
T9505 |
19663-19672 |
JJ |
denotes |
apoptotic |
T9506 |
19673-19678 |
NN |
denotes |
genes |
T9507 |
19678-19679 |
-COLON- |
denotes |
; |
T9508 |
19680-19687 |
VB |
denotes |
cleaved |
T9509 |
19688-19697 |
NN |
denotes |
caspase-3 |
T9510 |
19698-19701 |
CC |
denotes |
and |
T9511 |
19702-19703 |
CD |
denotes |
9 |
T9512 |
19703-19704 |
-COMMA- |
denotes |
, |
T9513 |
19705-19708 |
CC |
denotes |
and |
T9514 |
19709-19712 |
NN |
denotes |
Bax |
T9515 |
19713-19714 |
-LRB- |
denotes |
( |
T9516 |
19714-19720 |
NN |
denotes |
Figure |
T9517 |
19721-19725 |
NN |
denotes |
3A-D |
T9518 |
19725-19726 |
-RRB- |
denotes |
) |
T9519 |
19728-19730 |
IN |
denotes |
In |
T9520 |
19731-19734 |
DT |
denotes |
the |
T9521 |
19735-19740 |
NN |
denotes |
tumor |
T9522 |
19741-19744 |
CC |
denotes |
and |
T9523 |
19745-19748 |
DT |
denotes |
the |
T9524 |
19749-19755 |
NN |
denotes |
spleen |
T9525 |
19755-19756 |
-COMMA- |
denotes |
, |
T9526 |
19757-19760 |
DT |
denotes |
the |
T9527 |
19761-19767 |
NN |
denotes |
number |
T9528 |
19768-19770 |
IN |
denotes |
of |
T9529 |
19771-19780 |
JJ |
denotes |
cytotoxic |
T9530 |
19781-19785 |
JJ |
denotes |
CD8+ |
T9531 |
19786-19787 |
NN |
denotes |
T |
T9532 |
19788-19793 |
NN |
denotes |
cells |
T9533 |
19793-19794 |
-COMMA- |
denotes |
, |
T9534 |
19795-19800 |
JJ |
denotes |
CD57+ |
T9535 |
19801-19808 |
JJ |
denotes |
natural |
T9536 |
19809-19815 |
NN |
denotes |
killer |
T9537 |
19816-19821 |
NN |
denotes |
cells |
T9538 |
19821-19822 |
-COMMA- |
denotes |
, |
T9539 |
19823-19826 |
CC |
denotes |
and |
T9540 |
19827-19830 |
DT |
denotes |
the |
T9541 |
19831-19837 |
NN |
denotes |
levels |
T9542 |
19838-19840 |
IN |
denotes |
of |
T9543 |
19841-19847 |
NN |
denotes |
IL-1Ra |
T9544 |
19848-19852 |
VB |
denotes |
were |
T9545 |
19853-19862 |
VB |
denotes |
increased |
T9546 |
19863-19864 |
-LRB- |
denotes |
( |
T9547 |
19864-19870 |
NN |
denotes |
Figure |
T9548 |
19871-19872 |
CD |
denotes |
4 |
T9549 |
19873-19876 |
CC |
denotes |
and |
T9550 |
19877-19878 |
CD |
denotes |
5 |
T9551 |
19878-19879 |
-RRB- |
denotes |
) |
T9552 |
19881-19886 |
DT |
denotes |
These |
T9553 |
19887-19895 |
NN |
denotes |
findings |
T9554 |
19896-19903 |
VB |
denotes |
suggest |
T9555 |
19904-19908 |
IN |
denotes |
that |
T9556 |
19909-19917 |
NN |
denotes |
melanoma |
T9557 |
19918-19924 |
NN |
denotes |
growth |
T9558 |
19925-19928 |
VB |
denotes |
was |
T9559 |
19929-19938 |
VB |
denotes |
inhibited |
T9560 |
19939-19941 |
IN |
denotes |
in |
T9561 |
19942-19945 |
DT |
denotes |
the |
T9562 |
19946-19953 |
NN |
denotes |
CCR5−/− |
T9563 |
19954-19958 |
NN |
denotes |
mice |
T9564 |
19958-19959 |
-COMMA- |
denotes |
, |
T9565 |
19960-19963 |
CC |
denotes |
and |
T9566 |
19964-19968 |
IN |
denotes |
that |
T9567 |
19969-19972 |
DT |
denotes |
the |
T9568 |
19973-19982 |
NN |
denotes |
elevation |
T9569 |
19983-19985 |
IN |
denotes |
of |
T9570 |
19986-19992 |
NN |
denotes |
IL-1Ra |
T9571 |
19992-19993 |
-COMMA- |
denotes |
, |
T9572 |
19994-20005 |
VB |
denotes |
accompanied |
T9573 |
20006-20010 |
IN |
denotes |
with |
T9574 |
20011-20020 |
VB |
denotes |
decreased |
T9575 |
20021-20026 |
NN |
denotes |
NF-κB |
T9576 |
20026-20027 |
-COMMA- |
denotes |
, |
T9577 |
20028-20030 |
VB |
denotes |
is |
T9578 |
20031-20042 |
JJ |
denotes |
significant |
T9579 |
20043-20045 |
IN |
denotes |
in |
T9580 |
20046-20049 |
DT |
denotes |
the |
T9581 |
20050-20060 |
NN |
denotes |
inhibition |
T9582 |
20061-20063 |
IN |
denotes |
of |
T9583 |
20064-20072 |
NN |
denotes |
melanoma |
T9584 |
20073-20079 |
NN |
denotes |
growth |
T9585 |
20080-20082 |
IN |
denotes |
in |
T9586 |
20083-20090 |
NN |
denotes |
CCR5−/− |
T9587 |
20091-20095 |
NN |
denotes |
mice |
T9588 |
20097-20102 |
NN |
denotes |
NF-κB |
T9589 |
20103-20112 |
VB |
denotes |
regulates |
T9590 |
20113-20116 |
DT |
denotes |
the |
T9591 |
20117-20127 |
NN |
denotes |
expression |
T9592 |
20128-20130 |
IN |
denotes |
of |
T9593 |
20131-20135 |
IN |
denotes |
over |
T9594 |
20136-20139 |
CD |
denotes |
200 |
T9595 |
20140-20145 |
NN |
denotes |
genes |
T9596 |
20146-20150 |
WDT |
denotes |
that |
T9597 |
20151-20158 |
VB |
denotes |
control |
T9598 |
20159-20162 |
DT |
denotes |
the |
T9599 |
20163-20169 |
JJ |
denotes |
immune |
T9600 |
20170-20176 |
NN |
denotes |
system |
T9601 |
20176-20177 |
-COMMA- |
denotes |
, |
T9602 |
20178-20184 |
NN |
denotes |
cancer |
T9603 |
20185-20189 |
NN |
denotes |
cell |
T9604 |
20190-20196 |
NN |
denotes |
growth |
T9605 |
20197-20200 |
CC |
denotes |
and |
T9606 |
20201-20213 |
NN |
denotes |
inflammation |
T9607 |
20214-20215 |
-LRB- |
denotes |
[ |
T9608 |
20215-20217 |
CD |
denotes |
39 |
T9609 |
20217-20218 |
-RRB- |
denotes |
] |
T9610 |
20220-20227 |
IN |
denotes |
Because |
T9611 |
20228-20230 |
IN |
denotes |
of |
T9612 |
20231-20234 |
PRP-DOLLAR- |
denotes |
its |
T9613 |
20235-20244 |
NN |
denotes |
abilities |
T9614 |
20245-20247 |
TO |
denotes |
to |
T9615 |
20248-20254 |
VB |
denotes |
induce |
T9616 |
20255-20258 |
DT |
denotes |
the |
T9617 |
20259-20269 |
NN |
denotes |
expression |
T9618 |
20270-20272 |
IN |
denotes |
of |
T9619 |
20273-20274 |
DT |
denotes |
a |
T9620 |
20275-20280 |
JJ |
denotes |
large |
T9621 |
20281-20286 |
NN |
denotes |
array |
T9622 |
20287-20289 |
IN |
denotes |
of |
T9623 |
20290-20302 |
JJ |
denotes |
inflammatory |
T9624 |
20303-20312 |
NN |
denotes |
mediators |
T9625 |
20313-20316 |
CC |
denotes |
and |
T9626 |
20317-20320 |
PRP-DOLLAR- |
denotes |
its |
T9627 |
20321-20326 |
NN |
denotes |
roles |
T9628 |
20327-20329 |
IN |
denotes |
as |
T9629 |
20330-20334 |
NN |
denotes |
core |
T9630 |
20335-20348 |
NN |
denotes |
transcription |
T9631 |
20349-20356 |
NN |
denotes |
factors |
T9632 |
20357-20359 |
IN |
denotes |
in |
T9633 |
20360-20367 |
JJ |
denotes |
diverse |
T9634 |
20368-20374 |
JJ |
denotes |
immune |
T9635 |
20375-20384 |
NN |
denotes |
responses |
T9636 |
20384-20385 |
-COMMA- |
denotes |
, |
T9637 |
20386-20391 |
NN |
denotes |
NF-κB |
T9638 |
20392-20395 |
VB |
denotes |
has |
T9639 |
20396-20400 |
VB |
denotes |
been |
T9640 |
20401-20411 |
VB |
denotes |
recognized |
T9641 |
20412-20414 |
IN |
denotes |
as |
T9642 |
20415-20416 |
DT |
denotes |
a |
T9643 |
20417-20422 |
JJ |
denotes |
major |
T9644 |
20423-20429 |
NN |
denotes |
factor |
T9645 |
20430-20441 |
JJ |
denotes |
responsible |
T9646 |
20442-20445 |
IN |
denotes |
for |
T9647 |
20446-20465 |
JJ |
denotes |
cytokine-associated |
T9648 |
20466-20472 |
NN |
denotes |
cancer |
T9649 |
20473-20484 |
NN |
denotes |
development |
T9650 |
20485-20487 |
CC |
denotes |
or |
T9651 |
20488-20498 |
JJ |
denotes |
anti-tumor |
T9652 |
20499-20507 |
NN |
denotes |
immunity |
T9653 |
20509-20511 |
IN |
denotes |
In |
T9654 |
20512-20515 |
DT |
denotes |
the |
T9655 |
20516-20524 |
NN |
denotes |
melanoma |
T9656 |
20525-20530 |
NN |
denotes |
tumor |
T9657 |
20531-20538 |
NN |
denotes |
tissues |
T9658 |
20539-20541 |
IN |
denotes |
of |
T9659 |
20542-20545 |
DT |
denotes |
the |
T9660 |
20546-20553 |
NN |
denotes |
CCR5−/− |
T9661 |
20554-20558 |
NN |
denotes |
mice |
T9662 |
20558-20559 |
-COMMA- |
denotes |
, |
T9663 |
20560-20563 |
DT |
denotes |
the |
T9664 |
20564-20574 |
NN |
denotes |
expression |
T9665 |
20575-20577 |
IN |
denotes |
of |
T9666 |
20578-20583 |
NN |
denotes |
NF-κB |
T9667 |
20584-20590 |
NN |
denotes |
target |
T9668 |
20591-20595 |
NN |
denotes |
cell |
T9669 |
20596-20601 |
NN |
denotes |
death |
T9670 |
20602-20607 |
NN |
denotes |
genes |
T9671 |
20608-20609 |
-LRB- |
denotes |
( |
T9672 |
20609-20612 |
NN |
denotes |
Bax |
T9673 |
20612-20613 |
-COMMA- |
denotes |
, |
T9674 |
20614-20623 |
NN |
denotes |
caspase-3 |
T9675 |
20624-20627 |
CC |
denotes |
and |
T9676 |
20628-20629 |
CD |
denotes |
9 |
T9677 |
20629-20630 |
-RRB- |
denotes |
) |
T9678 |
20631-20634 |
CC |
denotes |
and |
T9679 |
20635-20638 |
DT |
denotes |
the |
T9680 |
20639-20642 |
NN |
denotes |
DNA |
T9681 |
20643-20650 |
NN |
denotes |
binding |
T9682 |
20651-20659 |
NN |
denotes |
activity |
T9683 |
20660-20662 |
IN |
denotes |
of |
T9684 |
20663-20668 |
NN |
denotes |
NF-κB |
T9685 |
20668-20669 |
-COMMA- |
denotes |
, |
T9686 |
20670-20674 |
VB |
denotes |
were |
T9687 |
20675-20688 |
RB |
denotes |
significantly |
T9688 |
20689-20698 |
VB |
denotes |
inhibited |
T9689 |
20698-20699 |
-COMMA- |
denotes |
, |
T9690 |
20700-20703 |
CC |
denotes |
but |
T9691 |
20704-20707 |
DT |
denotes |
the |
T9692 |
20708-20718 |
NN |
denotes |
expression |
T9693 |
20719-20721 |
IN |
denotes |
of |
T9694 |
20722-20726 |
NN |
denotes |
cell |
T9695 |
20727-20732 |
NN |
denotes |
death |
T9696 |
20733-20743 |
JJ |
denotes |
inhibitory |
T9697 |
20744-20749 |
NN |
denotes |
NF-κB |
T9698 |
20750-20756 |
NN |
denotes |
target |
T9699 |
20757-20762 |
NN |
denotes |
genes |
T9700 |
20762-20763 |
-COMMA- |
denotes |
, |
T9701 |
20764-20768 |
JJ |
denotes |
such |
T9702 |
20769-20771 |
IN |
denotes |
as |
T9703 |
20772-20777 |
NN |
denotes |
Bcl-2 |
T9704 |
20778-20781 |
CC |
denotes |
and |
T9705 |
20782-20786 |
NN |
denotes |
cIAP |
T9706 |
20787-20791 |
VB |
denotes |
were |
T9707 |
20792-20800 |
VB |
denotes |
enhanced |
T9708 |
20802-20804 |
IN |
denotes |
In |
T9709 |
20805-20813 |
NN |
denotes |
addition |
T9710 |
20813-20814 |
-COMMA- |
denotes |
, |
T9711 |
20815-20822 |
NN |
denotes |
CCR5−/− |
T9712 |
20823-20832 |
VB |
denotes |
prevented |
T9713 |
20833-20836 |
DT |
denotes |
the |
T9714 |
20837-20852 |
NN |
denotes |
phosphorylation |
T9715 |
20853-20855 |
IN |
denotes |
of |
T9716 |
20856-20859 |
NN |
denotes |
IκB |
T9717 |
20859-20860 |
-COMMA- |
denotes |
, |
T9718 |
20861-20872 |
VB |
denotes |
accompanied |
T9719 |
20873-20877 |
IN |
denotes |
with |
T9720 |
20878-20881 |
DT |
denotes |
the |
T9721 |
20882-20892 |
NN |
denotes |
inhibition |
T9722 |
20893-20895 |
IN |
denotes |
of |
T9723 |
20896-20899 |
DT |
denotes |
the |
T9724 |
20900-20903 |
NN |
denotes |
p50 |
T9725 |
20904-20907 |
CC |
denotes |
and |
T9726 |
20908-20911 |
NN |
denotes |
p65 |
T9727 |
20912-20925 |
NN |
denotes |
translocation |
T9728 |
20926-20930 |
IN |
denotes |
into |
T9729 |
20931-20934 |
DT |
denotes |
the |
T9730 |
20935-20942 |
NN |
denotes |
nucleus |
T9731 |
20943-20944 |
-LRB- |
denotes |
( |
T9732 |
20944-20950 |
NN |
denotes |
Figure |
T9733 |
20951-20955 |
NN |
denotes |
2A-C |
T9734 |
20955-20956 |
-RRB- |
denotes |
) |
T9735 |
20958-20962 |
JJ |
denotes |
Many |
T9736 |
20963-20969 |
NN |
denotes |
tumors |
T9737 |
20969-20970 |
-COMMA- |
denotes |
, |
T9738 |
20971-20980 |
VB |
denotes |
including |
T9739 |
20981-20989 |
NN |
denotes |
melanoma |
T9740 |
20989-20990 |
-COMMA- |
denotes |
, |
T9741 |
20991-20995 |
VB |
denotes |
have |
T9742 |
20996-21005 |
VB |
denotes |
increased |
T9743 |
21006-21012 |
NN |
denotes |
levels |
T9744 |
21013-21015 |
IN |
denotes |
of |
T9745 |
21016-21021 |
NN |
denotes |
NF-κB |
T9746 |
21022-21023 |
-LRB- |
denotes |
[ |
T9747 |
21023-21025 |
CD |
denotes |
40 |
T9748 |
21025-21026 |
-RRB- |
denotes |
] |
T9749 |
21026-21027 |
-COMMA- |
denotes |
, |
T9750 |
21028-21033 |
WDT |
denotes |
which |
T9751 |
21034-21036 |
VB |
denotes |
is |
T9752 |
21037-21043 |
RB |
denotes |
likely |
T9753 |
21044-21050 |
VB |
denotes |
acting |
T9754 |
21051-21053 |
IN |
denotes |
as |
T9755 |
21054-21055 |
DT |
denotes |
a |
T9756 |
21056-21064 |
NN |
denotes |
survival |
T9757 |
21065-21071 |
NN |
denotes |
factor |
T9758 |
21072-21075 |
IN |
denotes |
for |
T9759 |
21076-21084 |
NN |
denotes |
melanoma |
T9760 |
21085-21091 |
NN |
denotes |
growth |
T9761 |
21093-21097 |
RB |
denotes |
Thus |
T9762 |
21097-21098 |
-COMMA- |
denotes |
, |
T9763 |
21099-21102 |
DT |
denotes |
the |
T9764 |
21103-21114 |
NN |
denotes |
inhibitions |
T9765 |
21115-21117 |
IN |
denotes |
of |
T9766 |
21118-21123 |
NN |
denotes |
NF-κB |
T9767 |
21124-21132 |
NN |
denotes |
activity |
T9768 |
21133-21136 |
CC |
denotes |
and |
T9769 |
21137-21140 |
DT |
denotes |
the |
T9770 |
21141-21151 |
NN |
denotes |
expression |
T9771 |
21152-21154 |
IN |
denotes |
of |
T9772 |
21155-21161 |
NN |
denotes |
target |
T9773 |
21162-21167 |
NN |
denotes |
genes |
T9774 |
21168-21171 |
VB |
denotes |
are |
T9775 |
21172-21180 |
JJ |
denotes |
critical |
T9776 |
21181-21183 |
IN |
denotes |
in |
T9777 |
21184-21187 |
DT |
denotes |
the |
T9778 |
21188-21198 |
NN |
denotes |
inhibition |
T9779 |
21199-21201 |
IN |
denotes |
of |
T9780 |
21202-21207 |
NN |
denotes |
tumor |
T9781 |
21208-21214 |
NN |
denotes |
growth |
T9782 |
21215-21217 |
IN |
denotes |
in |
T9783 |
21218-21225 |
NN |
denotes |
CCR5−/− |
T9784 |
21226-21230 |
NN |
denotes |
mice |
T9785 |
21232-21240 |
IN |
denotes |
Although |
T9786 |
21241-21244 |
DT |
denotes |
the |
T9787 |
21245-21254 |
NN |
denotes |
mechanism |
T9788 |
21255-21257 |
VB |
denotes |
is |
T9789 |
21258-21261 |
RB |
denotes |
not |
T9790 |
21262-21267 |
JJ |
denotes |
clear |
T9791 |
21268-21270 |
IN |
denotes |
as |
T9792 |
21271-21273 |
TO |
denotes |
to |
T9793 |
21274-21277 |
WRB |
denotes |
how |
T9794 |
21278-21285 |
NN |
denotes |
CCR5−/− |
T9795 |
21286-21299 |
VB |
denotes |
downregulates |
T9796 |
21300-21305 |
NN |
denotes |
NF-κB |
T9797 |
21305-21306 |
-COMMA- |
denotes |
, |
T9798 |
21307-21309 |
PRP |
denotes |
it |
T9799 |
21310-21312 |
VB |
denotes |
is |
T9800 |
21313-21323 |
JJ |
denotes |
noteworthy |
T9801 |
21324-21328 |
IN |
denotes |
that |
T9802 |
21329-21334 |
NN |
denotes |
NF-κB |
T9803 |
21335-21337 |
VB |
denotes |
is |
T9804 |
21338-21347 |
VB |
denotes |
activated |
T9805 |
21348-21350 |
CC |
denotes |
or |
T9806 |
21351-21362 |
VB |
denotes |
inactivated |
T9807 |
21363-21365 |
IN |
denotes |
by |
T9808 |
21366-21370 |
JJ |
denotes |
many |
T9809 |
21371-21380 |
NN |
denotes |
cytokines |
T9810 |
21382-21390 |
JJ |
denotes |
Numerous |
T9811 |
21391-21398 |
NN |
denotes |
studies |
T9812 |
21399-21405 |
VB |
denotes |
showed |
T9813 |
21406-21410 |
IN |
denotes |
that |
T9814 |
21411-21419 |
NN |
denotes |
cytokine |
T9815 |
21420-21426 |
VB |
denotes |
affect |
T9816 |
21427-21432 |
NN |
denotes |
tumor |
T9817 |
21433-21439 |
NN |
denotes |
growth |
T9818 |
21440-21442 |
IN |
denotes |
by |
T9819 |
21443-21453 |
VB |
denotes |
regulating |
T9820 |
21454-21459 |
NN |
denotes |
NF-κB |
T9821 |
21461-21473 |
JJ |
denotes |
Inflammatory |
T9822 |
21474-21483 |
NN |
denotes |
cytokines |
T9823 |
21483-21484 |
-COMMA- |
denotes |
, |
T9824 |
21485-21494 |
VB |
denotes |
including |
T9825 |
21495-21499 |
NN |
denotes |
IL-1 |
T9826 |
21499-21500 |
-COMMA- |
denotes |
, |
T9827 |
21501-21505 |
NN |
denotes |
IL-6 |
T9828 |
21506-21509 |
CC |
denotes |
and |
T9829 |
21510-21514 |
NN |
denotes |
IL-8 |
T9830 |
21514-21515 |
-COMMA- |
denotes |
, |
T9831 |
21516-21524 |
VB |
denotes |
activate |
T9832 |
21525-21530 |
NN |
denotes |
NF-κB |
T9833 |
21531-21539 |
NN |
denotes |
pathways |
T9834 |
21540-21542 |
IN |
denotes |
in |
T9835 |
21543-21548 |
NN |
denotes |
tumor |
T9836 |
21549-21554 |
NN |
denotes |
cells |
T9837 |
21555-21556 |
-LRB- |
denotes |
[ |
T9838 |
21556-21558 |
CD |
denotes |
41 |
T9839 |
21558-21559 |
-RRB- |
denotes |
] |
T9840 |
21561-21564 |
DT |
denotes |
The |
T9841 |
21565-21576 |
NN |
denotes |
interleukin |
T9842 |
21577-21579 |
CD |
denotes |
10 |
T9843 |
21580-21581 |
-LRB- |
denotes |
( |
T9844 |
21581-21586 |
NN |
denotes |
IL-10 |
T9845 |
21586-21587 |
-RRB- |
denotes |
) |
T9846 |
21588-21590 |
VB |
denotes |
is |
T9847 |
21591-21595 |
RB |
denotes |
well |
T9848 |
21596-21601 |
VB |
denotes |
known |
T9849 |
21602-21604 |
IN |
denotes |
as |
T9850 |
21605-21607 |
DT |
denotes |
an |
T9851 |
21608-21618 |
JJ |
denotes |
anti-tumor |
T9852 |
21619-21625 |
NN |
denotes |
factor |
T9853 |
21626-21628 |
RB |
denotes |
as |
T9854 |
21629-21633 |
RB |
denotes |
well |
T9855 |
21634-21636 |
IN |
denotes |
as |
T9856 |
21637-21639 |
DT |
denotes |
an |
T9857 |
21640-21657 |
JJ |
denotes |
anti-inflammatory |
T9858 |
21658-21664 |
NN |
denotes |
factor |
T9859 |
21665-21666 |
-LRB- |
denotes |
[ |
T9860 |
21666-21668 |
CD |
denotes |
42 |
T9861 |
21668-21669 |
-RRB- |
denotes |
] |
T9862 |
21669-21670 |
-COMMA- |
denotes |
, |
T9863 |
21671-21672 |
-LRB- |
denotes |
[ |
T9864 |
21672-21674 |
CD |
denotes |
43 |
T9865 |
21674-21675 |
-RRB- |
denotes |
] |
T9866 |
21677-21682 |
NN |
denotes |
IL-10 |
T9867 |
21683-21691 |
VB |
denotes |
inhibits |
T9868 |
21692-21706 |
RB |
denotes |
constitutively |
T9869 |
21707-21716 |
VB |
denotes |
activated |
T9870 |
21717-21722 |
NN |
denotes |
NF-κB |
T9871 |
21723-21727 |
CC |
denotes |
both |
T9872 |
21728-21730 |
FW |
denotes |
in |
T9873 |
21731-21736 |
FW |
denotes |
vitro |
T9874 |
21737-21738 |
-LRB- |
denotes |
[ |
T9875 |
21738-21740 |
CD |
denotes |
44 |
T9876 |
21740-21741 |
-RRB- |
denotes |
] |
T9877 |
21742-21745 |
CC |
denotes |
and |
T9878 |
21746-21748 |
FW |
denotes |
in |
T9879 |
21749-21753 |
FW |
denotes |
vivo |
T9880 |
21754-21755 |
-LRB- |
denotes |
[ |
T9881 |
21755-21757 |
CD |
denotes |
45 |
T9882 |
21757-21758 |
-RRB- |
denotes |
] |
T9883 |
21760-21770 |
NN |
denotes |
Inhibition |
T9884 |
21771-21773 |
IN |
denotes |
of |
T9885 |
21774-21779 |
NN |
denotes |
NF-κB |
T9886 |
21780-21782 |
IN |
denotes |
by |
T9887 |
21783-21786 |
DT |
denotes |
the |
T9888 |
21787-21792 |
NN |
denotes |
IL-10 |
T9889 |
21793-21804 |
VB |
denotes |
contributes |
T9890 |
21805-21807 |
TO |
denotes |
to |
T9891 |
21808-21811 |
DT |
denotes |
the |
T9892 |
21812-21822 |
JJ |
denotes |
anti-tumor |
T9893 |
21823-21830 |
NN |
denotes |
effects |
T9894 |
21831-21838 |
IN |
denotes |
through |
T9895 |
21839-21842 |
DT |
denotes |
the |
T9896 |
21843-21853 |
NN |
denotes |
activation |
T9897 |
21854-21856 |
IN |
denotes |
of |
T9898 |
21857-21866 |
NN |
denotes |
caspase-3 |
T9899 |
21867-21870 |
CC |
denotes |
and |
T9900 |
21871-21880 |
NN |
denotes |
apoptosis |
T9901 |
21881-21883 |
IN |
denotes |
in |
T9902 |
21884-21899 |
JJ |
denotes |
Colon26-bearing |
T9903 |
21900-21904 |
NN |
denotes |
mice |
T9904 |
21905-21906 |
-LRB- |
denotes |
[ |
T9905 |
21906-21908 |
CD |
denotes |
43 |
T9906 |
21908-21909 |
-RRB- |
denotes |
] |
T9907 |
21911-21920 |
RB |
denotes |
Similarly |
T9908 |
21920-21921 |
-COMMA- |
denotes |
, |
T9909 |
21922-21929 |
JJ |
denotes |
several |
T9910 |
21930-21937 |
NN |
denotes |
studies |
T9911 |
21938-21942 |
VB |
denotes |
have |
T9912 |
21943-21955 |
VB |
denotes |
demonstrated |
T9913 |
21956-21959 |
DT |
denotes |
the |
T9914 |
21960-21967 |
NN |
denotes |
ability |
T9915 |
21968-21970 |
IN |
denotes |
of |
T9916 |
21971-21977 |
NN |
denotes |
IL-1Ra |
T9917 |
21978-21980 |
TO |
denotes |
to |
T9918 |
21981-21989 |
VB |
denotes |
abrogate |
T9919 |
21990-21993 |
DT |
denotes |
the |
T9920 |
21994-22009 |
JJ |
denotes |
proinflammatory |
T9921 |
22010-22017 |
NN |
denotes |
effects |
T9922 |
22018-22020 |
IN |
denotes |
of |
T9923 |
22021-22025 |
NN |
denotes |
IL-1 |
T9924 |
22026-22027 |
-LRB- |
denotes |
[ |
T9925 |
22027-22029 |
CD |
denotes |
46 |
T9926 |
22029-22030 |
-RRB- |
denotes |
] |
T9927 |
22032-22034 |
PRP |
denotes |
It |
T9928 |
22035-22038 |
VB |
denotes |
has |
T9929 |
22039-22043 |
VB |
denotes |
been |
T9930 |
22044-22052 |
VB |
denotes |
reported |
T9931 |
22053-22057 |
IN |
denotes |
that |
T9932 |
22058-22062 |
NN |
denotes |
IL-1 |
T9933 |
22063-22070 |
VB |
denotes |
induces |
T9934 |
22071-22074 |
DT |
denotes |
the |
T9935 |
22075-22085 |
NN |
denotes |
activation |
T9936 |
22086-22088 |
IN |
denotes |
of |
T9937 |
22089-22094 |
NN |
denotes |
NF-κB |
T9938 |
22095-22097 |
IN |
denotes |
in |
T9939 |
22098-22105 |
JJ |
denotes |
several |
T9940 |
22106-22113 |
NN |
denotes |
cancers |
T9941 |
22113-22114 |
-COMMA- |
denotes |
, |
T9942 |
22115-22118 |
CC |
denotes |
and |
T9943 |
22119-22128 |
VB |
denotes |
increases |
T9944 |
22129-22133 |
NN |
denotes |
cell |
T9945 |
22134-22139 |
NN |
denotes |
cycle |
T9946 |
22140-22151 |
NN |
denotes |
progression |
T9947 |
22151-22152 |
-COMMA- |
denotes |
, |
T9948 |
22153-22156 |
CC |
denotes |
and |
T9949 |
22157-22160 |
DT |
denotes |
the |
T9950 |
22161-22172 |
NN |
denotes |
suppression |
T9951 |
22173-22175 |
IN |
denotes |
of |
T9952 |
22176-22185 |
JJ |
denotes |
apoptotic |
T9953 |
22186-22190 |
NN |
denotes |
cell |
T9954 |
22191-22196 |
NN |
denotes |
death |
T9955 |
22197-22204 |
VB |
denotes |
leading |
T9956 |
22205-22207 |
TO |
denotes |
to |
T9957 |
22208-22213 |
NN |
denotes |
tumor |
T9958 |
22214-22223 |
NN |
denotes |
promotion |
T9959 |
22225-22228 |
DT |
denotes |
The |
T9960 |
22229-22236 |
NN |
denotes |
results |
T9961 |
22237-22239 |
IN |
denotes |
of |
T9962 |
22240-22247 |
JJ |
denotes |
various |
T9963 |
22248-22255 |
NN |
denotes |
studies |
T9964 |
22256-22260 |
IN |
denotes |
over |
T9965 |
22261-22264 |
DT |
denotes |
the |
T9966 |
22265-22269 |
JJ |
denotes |
past |
T9967 |
22270-22272 |
CD |
denotes |
10 |
T9968 |
22273-22278 |
NN |
denotes |
years |
T9969 |
22279-22287 |
VB |
denotes |
indicate |
T9970 |
22288-22292 |
IN |
denotes |
that |
T9971 |
22293-22296 |
DT |
denotes |
the |
T9972 |
22297-22302 |
JJ |
denotes |
major |
T9973 |
22303-22311 |
NN |
denotes |
function |
T9974 |
22312-22314 |
IN |
denotes |
of |
T9975 |
22315-22321 |
NN |
denotes |
IL-1Ra |
T9976 |
22322-22324 |
VB |
denotes |
is |
T9977 |
22325-22327 |
TO |
denotes |
to |
T9978 |
22328-22336 |
VB |
denotes |
regulate |
T9979 |
22337-22340 |
DT |
denotes |
the |
T9980 |
22341-22352 |
JJ |
denotes |
pleiotropic |
T9981 |
22353-22360 |
NN |
denotes |
effects |
T9982 |
22361-22363 |
IN |
denotes |
of |
T9983 |
22364-22368 |
NN |
denotes |
IL-1 |
T9984 |
22369-22371 |
IN |
denotes |
by |
T9985 |
22372-22385 |
RB |
denotes |
competitively |
T9986 |
22386-22394 |
VB |
denotes |
blocking |
T9987 |
22395-22398 |
PRP-DOLLAR- |
denotes |
its |
T9988 |
22399-22408 |
NN |
denotes |
functions |
T9989 |
22409-22410 |
-LRB- |
denotes |
[ |
T9990 |
22410-22412 |
CD |
denotes |
47 |
T9991 |
22412-22413 |
-RRB- |
denotes |
] |
T9992 |
22415-22418 |
DT |
denotes |
The |
T9993 |
22419-22426 |
NN |
denotes |
ability |
T9994 |
22427-22429 |
IN |
denotes |
of |
T9995 |
22430-22434 |
NN |
denotes |
IL-1 |
T9996 |
22435-22437 |
TO |
denotes |
to |
T9997 |
22438-22444 |
VB |
denotes |
induce |
T9998 |
22445-22448 |
PRP-DOLLAR- |
denotes |
its |
T9999 |
22449-22452 |
JJ |
denotes |
own |
T10000 |
22453-22463 |
NN |
denotes |
antagonist |
T10001 |
22464-22466 |
VB |
denotes |
is |
T10002 |
22467-22469 |
IN |
denotes |
of |
T10003 |
22470-22478 |
NN |
denotes |
interest |
T10004 |
22479-22481 |
IN |
denotes |
in |
T10005 |
22482-22495 |
VB |
denotes |
understanding |
T10006 |
22496-22499 |
DT |
denotes |
the |
T10007 |
22500-22510 |
NN |
denotes |
regulation |
T10008 |
22511-22514 |
CC |
denotes |
and |
T10009 |
22515-22528 |
NN |
denotes |
dysregulation |
T10010 |
22529-22531 |
IN |
denotes |
of |
T10011 |
22532-22536 |
NN |
denotes |
IL-1 |
T10012 |
22537-22546 |
NN |
denotes |
signaling |
T10013 |
22547-22549 |
IN |
denotes |
in |
T10014 |
22550-22556 |
JJ |
denotes |
normal |
T10015 |
22557-22560 |
CC |
denotes |
and |
T10016 |
22561-22569 |
JJ |
denotes |
diseased |
T10017 |
22570-22576 |
NN |
denotes |
tissue |
T10018 |
22578-22591 |
NN |
denotes |
Up-regulation |
T10019 |
22592-22594 |
IN |
denotes |
of |
T10020 |
22595-22598 |
DT |
denotes |
the |
T10021 |
22599-22607 |
NN |
denotes |
receptor |
T10022 |
22608-22618 |
NN |
denotes |
antagonist |
T10023 |
22619-22629 |
VB |
denotes |
represents |
T10024 |
22630-22631 |
DT |
denotes |
a |
T10025 |
22632-22641 |
NN |
denotes |
mechanism |
T10026 |
22642-22645 |
IN |
denotes |
for |
T10027 |
22646-22653 |
VB |
denotes |
turning |
T10028 |
22654-22657 |
RP |
denotes |
off |
T10029 |
22658-22662 |
NN |
denotes |
IL-1 |
T10030 |
22663-22672 |
NN |
denotes |
signaling |
T10031 |
22673-22676 |
CC |
denotes |
and |
T10032 |
22677-22685 |
VB |
denotes |
creating |
T10033 |
22686-22687 |
DT |
denotes |
a |
T10034 |
22688-22697 |
JJ |
denotes |
temporary |
T10035 |
22698-22703 |
NN |
denotes |
state |
T10036 |
22704-22706 |
IN |
denotes |
of |
T10037 |
22707-22721 |
NN |
denotes |
refractoriness |
T10038 |
22723-22726 |
DT |
denotes |
The |
T10039 |
22727-22735 |
VB |
denotes |
elevated |
T10040 |
22736-22746 |
NN |
denotes |
expression |
T10041 |
22747-22749 |
IN |
denotes |
of |
T10042 |
22750-22756 |
NN |
denotes |
IL-1Ra |
T10043 |
22756-22757 |
-COMMA- |
denotes |
, |
T10044 |
22758-22765 |
IN |
denotes |
without |
T10045 |
22766-22769 |
DT |
denotes |
any |
T10046 |
22770-22776 |
NN |
denotes |
change |
T10047 |
22777-22779 |
IN |
denotes |
of |
T10048 |
22780-22784 |
NN |
denotes |
IL-1 |
T10049 |
22785-22787 |
IN |
denotes |
in |
T10050 |
22788-22794 |
NN |
denotes |
tumors |
T10051 |
22794-22795 |
-COMMA- |
denotes |
, |
T10052 |
22796-22804 |
VB |
denotes |
suggests |
T10053 |
22805-22809 |
IN |
denotes |
that |
T10054 |
22810-22813 |
DT |
denotes |
the |
T10055 |
22814-22828 |
JJ |
denotes |
IL-1-signaling |
T10056 |
22829-22835 |
NN |
denotes |
system |
T10057 |
22836-22839 |
MD |
denotes |
may |
T10058 |
22840-22842 |
VB |
denotes |
be |
T10059 |
22843-22855 |
VB |
denotes |
dysregulated |
T10060 |
22856-22858 |
IN |
denotes |
by |
T10061 |
22859-22865 |
NN |
denotes |
IL-1Ra |
T10062 |
22866-22868 |
IN |
denotes |
in |
T10063 |
22869-22875 |
NN |
denotes |
tumors |
T10064 |
22877-22883 |
NN |
denotes |
IL-1Ra |
T10065 |
22884-22887 |
VB |
denotes |
has |
T10066 |
22888-22892 |
VB |
denotes |
been |
T10067 |
22893-22898 |
VB |
denotes |
shown |
T10068 |
22899-22901 |
TO |
denotes |
to |
T10069 |
22902-22909 |
VB |
denotes |
inhibit |
T10070 |
22910-22915 |
NN |
denotes |
tumor |
T10071 |
22916-22927 |
NN |
denotes |
progression |
T10072 |
22928-22930 |
IN |
denotes |
in |
T10073 |
22931-22939 |
NN |
denotes |
prostate |
T10074 |
22939-22940 |
-COMMA- |
denotes |
, |
T10075 |
22941-22947 |
NN |
denotes |
breast |
T10076 |
22947-22948 |
-COMMA- |
denotes |
, |
T10077 |
22949-22952 |
CC |
denotes |
and |
T10078 |
22953-22957 |
NN |
denotes |
skin |
T10079 |
22958-22964 |
NN |
denotes |
cancer |
T10080 |
22965-22966 |
-LRB- |
denotes |
[ |
T10081 |
22966-22968 |
CD |
denotes |
14 |
T10082 |
22968-22969 |
-RRB- |
denotes |
] |
T10083 |
22969-22970 |
-COMMA- |
denotes |
, |
T10084 |
22971-22972 |
-LRB- |
denotes |
[ |
T10085 |
22972-22974 |
CD |
denotes |
15 |
T10086 |
22974-22975 |
-RRB- |
denotes |
] |
T10087 |
22975-22976 |
-COMMA- |
denotes |
, |
T10088 |
22977-22978 |
-LRB- |
denotes |
[ |
T10089 |
22978-22980 |
CD |
denotes |
16 |
T10090 |
22980-22981 |
-RRB- |
denotes |
] |
T10091 |
22983-22996 |
JJ |
denotes |
Intracellular |
T10092 |
22997-23003 |
NN |
denotes |
IL-1Ra |
T10093 |
23004-23005 |
-LRB- |
denotes |
( |
T10094 |
23005-23013 |
NN |
denotes |
icIL-1Ra |
T10095 |
23013-23014 |
-RRB- |
denotes |
) |
T10096 |
23015-23023 |
VB |
denotes |
inhibits |
T10097 |
23024-23028 |
NN |
denotes |
IL-6 |
T10098 |
23029-23032 |
CC |
denotes |
and |
T10099 |
23033-23037 |
NN |
denotes |
IL-8 |
T10100 |
23038-23048 |
NN |
denotes |
production |
T10101 |
23049-23051 |
IN |
denotes |
in |
T10102 |
23052-23058 |
NN |
denotes |
Caco-2 |
T10103 |
23059-23064 |
NN |
denotes |
cells |
T10104 |
23065-23067 |
IN |
denotes |
by |
T10105 |
23068-23076 |
VB |
denotes |
blocking |
T10106 |
23077-23082 |
NN |
denotes |
NF-κB |
T10107 |
23083-23091 |
NN |
denotes |
pathways |
T10108 |
23092-23093 |
-LRB- |
denotes |
[ |
T10109 |
23093-23095 |
CD |
denotes |
37 |
T10110 |
23095-23096 |
-RRB- |
denotes |
] |
T10111 |
23098-23100 |
PRP |
denotes |
We |
T10112 |
23101-23106 |
VB |
denotes |
found |
T10113 |
23107-23111 |
IN |
denotes |
that |
T10114 |
23112-23115 |
DT |
denotes |
the |
T10115 |
23116-23122 |
NN |
denotes |
levels |
T10116 |
23123-23125 |
IN |
denotes |
of |
T10117 |
23126-23132 |
NN |
denotes |
IL-1Ra |
T10118 |
23133-23137 |
VB |
denotes |
were |
T10119 |
23138-23151 |
RB |
denotes |
significantly |
T10120 |
23152-23160 |
VB |
denotes |
elevated |
T10121 |
23161-23163 |
IN |
denotes |
in |
T10122 |
23164-23167 |
DT |
denotes |
the |
T10123 |
23168-23173 |
NN |
denotes |
tumor |
T10124 |
23174-23181 |
NN |
denotes |
tissues |
T10125 |
23182-23184 |
IN |
denotes |
of |
T10126 |
23185-23192 |
NN |
denotes |
CCR5−/− |
T10127 |
23193-23197 |
NN |
denotes |
mice |
T10128 |
23198-23208 |
VB |
denotes |
inoculated |
T10129 |
23209-23213 |
IN |
denotes |
with |
T10130 |
23214-23217 |
NN |
denotes |
B16 |
T10131 |
23218-23226 |
NN |
denotes |
melanoma |
T10132 |
23227-23232 |
NN |
denotes |
cells |
T10133 |
23234-23239 |
VB |
denotes |
Taken |
T10134 |
23240-23248 |
RB |
denotes |
together |
T10135 |
23248-23249 |
-COMMA- |
denotes |
, |
T10136 |
23250-23255 |
DT |
denotes |
these |
T10137 |
23256-23260 |
NN |
denotes |
data |
T10138 |
23261-23269 |
VB |
denotes |
indicate |
T10139 |
23270-23276 |
NN |
denotes |
IL-1Ra |
T10140 |
23277-23282 |
MD |
denotes |
could |
T10141 |
23283-23285 |
VB |
denotes |
be |
T10142 |
23286-23296 |
RB |
denotes |
critically |
T10143 |
23297-23305 |
VB |
denotes |
involved |
T10144 |
23306-23308 |
IN |
denotes |
in |
T10145 |
23309-23312 |
DT |
denotes |
the |
T10146 |
23313-23318 |
NN |
denotes |
tumor |
T10147 |
23319-23325 |
NN |
denotes |
growth |
T10148 |
23326-23336 |
NN |
denotes |
inhibition |
T10149 |
23337-23339 |
IN |
denotes |
of |
T10150 |
23340-23347 |
NN |
denotes |
CCR5−/− |
T10151 |
23348-23352 |
NN |
denotes |
mice |
T10152 |
23353-23360 |
IN |
denotes |
through |
T10153 |
23361-23364 |
DT |
denotes |
the |
T10154 |
23365-23377 |
NN |
denotes |
inactivation |
T10155 |
23378-23380 |
IN |
denotes |
of |
T10156 |
23381-23386 |
NN |
denotes |
NF-κB |
T10157 |
23387-23389 |
IN |
denotes |
in |
T10158 |
23390-23393 |
DT |
denotes |
the |
T10159 |
23394-23401 |
JJ |
denotes |
present |
T10160 |
23402-23407 |
NN |
denotes |
study |
T10161 |
23409-23413 |
NN |
denotes |
CCR5 |
T10162 |
23414-23423 |
VB |
denotes |
increases |
T10163 |
23424-23429 |
NN |
denotes |
tumor |
T10164 |
23430-23436 |
NN |
denotes |
growth |
T10165 |
23437-23439 |
IN |
denotes |
in |
T10166 |
23440-23441 |
DT |
denotes |
a |
T10167 |
23442-23447 |
JJ |
denotes |
local |
T10168 |
23448-23453 |
NN |
denotes |
model |
T10169 |
23454-23457 |
CC |
denotes |
and |
T10170 |
23458-23466 |
VB |
denotes |
inhibits |
T10171 |
23467-23470 |
DT |
denotes |
the |
T10172 |
23471-23479 |
NN |
denotes |
efficacy |
T10173 |
23480-23482 |
IN |
denotes |
of |
T10174 |
23483-23484 |
DT |
denotes |
a |
T10175 |
23485-23493 |
NN |
denotes |
dendrite |
T10176 |
23494-23498 |
NN |
denotes |
cell |
T10177 |
23499-23506 |
NN |
denotes |
vaccine |
T10178 |
23507-23509 |
IN |
denotes |
in |
T10179 |
23510-23517 |
JJ |
denotes |
CCR5+/+ |
T10180 |
23518-23522 |
NN |
denotes |
mice |
T10181 |
23523-23531 |
VB |
denotes |
compared |
T10182 |
23532-23536 |
IN |
denotes |
with |
T10183 |
23537-23544 |
NN |
denotes |
CCR5−/− |
T10184 |
23545-23549 |
NN |
denotes |
mice |
T10185 |
23550-23551 |
-LRB- |
denotes |
[ |
T10186 |
23551-23553 |
CD |
denotes |
10 |
T10187 |
23553-23554 |
-RRB- |
denotes |
] |
T10188 |
23556-23561 |
NNP |
denotes |
Cheng |
T10189 |
23562-23563 |
NNP |
denotes |
J |
T10190 |
23564-23567 |
CC |
denotes |
and |
T10191 |
23568-23572 |
NNP |
denotes |
Sung |
T10192 |
23573-23575 |
NNP |
denotes |
RS |
T10193 |
23576-23584 |
VB |
denotes |
examined |
T10194 |
23585-23588 |
DT |
denotes |
the |
T10195 |
23589-23595 |
NN |
denotes |
effect |
T10196 |
23596-23598 |
IN |
denotes |
of |
T10197 |
23599-23603 |
NN |
denotes |
CCR5 |
T10198 |
23604-23606 |
IN |
denotes |
on |
T10199 |
23607-23610 |
DT |
denotes |
the |
T10200 |
23611-23617 |
JJ |
denotes |
immune |
T10201 |
23618-23626 |
NN |
denotes |
response |
T10202 |
23627-23629 |
TO |
denotes |
to |
T10203 |
23630-23640 |
NN |
denotes |
adenovirus |
T10204 |
23641-23648 |
NN |
denotes |
vectors |
T10205 |
23649-23652 |
CC |
denotes |
and |
T10206 |
23653-23658 |
NN |
denotes |
graft |
T10207 |
23659-23667 |
NN |
denotes |
function |
T10208 |
23668-23670 |
IN |
denotes |
in |
T10209 |
23671-23673 |
DT |
denotes |
an |
T10210 |
23674-23679 |
NN |
denotes |
islet |
T10211 |
23680-23690 |
NN |
denotes |
transplant |
T10212 |
23691-23696 |
NN |
denotes |
model |
T10213 |
23698-23702 |
PRP |
denotes |
They |
T10214 |
23703-23708 |
VB |
denotes |
found |
T10215 |
23709-23713 |
IN |
denotes |
that |
T10216 |
23714-23718 |
NN |
denotes |
CCR5 |
T10217 |
23719-23726 |
NN |
denotes |
absence |
T10218 |
23727-23731 |
VB |
denotes |
does |
T10219 |
23732-23735 |
RB |
denotes |
not |
T10220 |
23736-23743 |
VB |
denotes |
prevent |
T10221 |
23744-23747 |
DT |
denotes |
the |
T10222 |
23748-23753 |
JJ |
denotes |
local |
T10223 |
23754-23760 |
JJ |
denotes |
immune |
T10224 |
23761-23769 |
NN |
denotes |
response |
T10225 |
23770-23772 |
TO |
denotes |
to |
T10226 |
23773-23783 |
NN |
denotes |
adenovirus |
T10227 |
23784-23796 |
NN |
denotes |
transduction |
T10228 |
23797-23798 |
-LRB- |
denotes |
[ |
T10229 |
23798-23800 |
CD |
denotes |
48 |
T10230 |
23800-23801 |
-RRB- |
denotes |
] |
T10231 |
23803-23815 |
RB |
denotes |
Additionally |
T10232 |
23815-23816 |
-COMMA- |
denotes |
, |
T10233 |
23817-23820 |
NNP |
denotes |
Tan |
T10234 |
23821-23823 |
NNP |
denotes |
MC |
T10235 |
23824-23826 |
FW |
denotes |
et |
T10236 |
23827-23830 |
FW |
denotes |
al. |
T10237 |
23831-23840 |
VB |
denotes |
suggested |
T10238 |
23841-23845 |
IN |
denotes |
that |
T10239 |
23846-23856 |
NN |
denotes |
disruption |
T10240 |
23857-23859 |
IN |
denotes |
of |
T10241 |
23860-23869 |
NN |
denotes |
CCR5/CCL5 |
T10242 |
23870-23879 |
NN |
denotes |
signaling |
T10243 |
23879-23880 |
-COMMA- |
denotes |
, |
T10244 |
23881-23887 |
CC |
denotes |
either |
T10245 |
23888-23890 |
IN |
denotes |
by |
T10246 |
23891-23899 |
VB |
denotes |
reducing |
T10247 |
23900-23904 |
NN |
denotes |
CCL5 |
T10248 |
23905-23915 |
NN |
denotes |
production |
T10249 |
23916-23918 |
IN |
denotes |
by |
T10250 |
23919-23924 |
NN |
denotes |
tumor |
T10251 |
23925-23930 |
NN |
denotes |
cells |
T10252 |
23931-23933 |
CC |
denotes |
or |
T10253 |
23934-23936 |
IN |
denotes |
by |
T10254 |
23937-23945 |
JJ |
denotes |
systemic |
T10255 |
23946-23960 |
NN |
denotes |
administration |
T10256 |
23961-23963 |
IN |
denotes |
of |
T10257 |
23964-23965 |
DT |
denotes |
a |
T10258 |
23966-23970 |
NN |
denotes |
CCR5 |
T10259 |
23971-23980 |
NN |
denotes |
inhibitor |
T10260 |
23981-23982 |
-LRB- |
denotes |
( |
T10261 |
23982-23989 |
NN |
denotes |
TAK-779 |
T10262 |
23989-23990 |
-RRB- |
denotes |
) |
T10263 |
23990-23991 |
-COMMA- |
denotes |
, |
T10264 |
23992-23999 |
VB |
denotes |
reduced |
T10265 |
24000-24004 |
NNP |
denotes |
Treg |
T10266 |
24005-24006 |
-LRB- |
denotes |
( |
T10267 |
24006-24016 |
JJ |
denotes |
regulatory |
T10268 |
24017-24018 |
NN |
denotes |
T |
T10269 |
24019-24024 |
NN |
denotes |
cells |
T10270 |
24024-24025 |
-RRB- |
denotes |
) |
T10271 |
24026-24035 |
NN |
denotes |
migration |
T10272 |
24036-24038 |
TO |
denotes |
to |
T10273 |
24039-24045 |
NN |
denotes |
tumors |
T10274 |
24046-24048 |
IN |
denotes |
so |
T10275 |
24049-24053 |
IN |
denotes |
that |
T10276 |
24054-24060 |
NN |
denotes |
tumors |
T10277 |
24061-24064 |
VB |
denotes |
are |
T10278 |
24065-24072 |
JJ |
denotes |
smaller |
T10279 |
24073-24075 |
IN |
denotes |
in |
T10280 |
24076-24083 |
NN |
denotes |
control |
T10281 |
24084-24088 |
NN |
denotes |
mice |
T10282 |
24089-24090 |
-LRB- |
denotes |
[ |
T10283 |
24090-24091 |
CD |
denotes |
9 |
T10284 |
24091-24092 |
-RRB- |
denotes |
] |
T10285 |
24094-24099 |
DT |
denotes |
These |
T10286 |
24100-24104 |
NN |
denotes |
data |
T10287 |
24105-24112 |
VB |
denotes |
support |
T10288 |
24113-24116 |
DT |
denotes |
the |
T10289 |
24117-24126 |
JJ |
denotes |
important |
T10290 |
24127-24134 |
NN |
denotes |
premise |
T10291 |
24135-24139 |
IN |
denotes |
that |
T10292 |
24140-24150 |
NN |
denotes |
inhibition |
T10293 |
24151-24153 |
IN |
denotes |
of |
T10294 |
24154-24159 |
NN |
denotes |
tumor |
T10295 |
24160-24166 |
NN |
denotes |
growth |
T10296 |
24167-24169 |
IN |
denotes |
in |
T10297 |
24170-24177 |
NN |
denotes |
CCR5−/− |
T10298 |
24178-24182 |
NN |
denotes |
mice |
T10299 |
24183-24188 |
MD |
denotes |
could |
T10300 |
24189-24191 |
VB |
denotes |
be |
T10301 |
24192-24199 |
VB |
denotes |
related |
T10302 |
24200-24204 |
IN |
denotes |
with |
T10303 |
24205-24208 |
DT |
denotes |
the |
T10304 |
24209-24219 |
NN |
denotes |
inhibition |
T10305 |
24220-24222 |
IN |
denotes |
of |
T10306 |
24223-24229 |
JJ |
denotes |
immune |
T10307 |
24230-24236 |
NN |
denotes |
escape |
T10308 |
24238-24245 |
JJ |
denotes |
Similar |
T10309 |
24246-24248 |
TO |
denotes |
to |
T10310 |
24249-24253 |
DT |
denotes |
this |
T10311 |
24254-24261 |
NN |
denotes |
finding |
T10312 |
24261-24262 |
-COMMA- |
denotes |
, |
T10313 |
24263-24265 |
PRP |
denotes |
we |
T10314 |
24266-24271 |
VB |
denotes |
found |
T10315 |
24272-24276 |
IN |
denotes |
that |
T10316 |
24277-24280 |
DT |
denotes |
the |
T10317 |
24281-24288 |
JJ |
denotes |
CCR5+/+ |
T10318 |
24289-24293 |
NN |
denotes |
mice |
T10319 |
24294-24302 |
VB |
denotes |
injected |
T10320 |
24303-24307 |
IN |
denotes |
with |
T10321 |
24308-24316 |
NN |
denotes |
melanoma |
T10322 |
24317-24322 |
NN |
denotes |
cells |
T10323 |
24323-24333 |
RB |
denotes |
apparently |
T10324 |
24334-24338 |
VB |
denotes |
have |
T10325 |
24339-24340 |
DT |
denotes |
a |
T10326 |
24341-24346 |
JJ |
denotes |
lower |
T10327 |
24347-24353 |
NN |
denotes |
number |
T10328 |
24354-24356 |
IN |
denotes |
of |
T10329 |
24357-24366 |
JJ |
denotes |
cytotoxic |
T10330 |
24367-24368 |
NN |
denotes |
T |
T10331 |
24369-24374 |
NN |
denotes |
cells |
T10332 |
24375-24376 |
-LRB- |
denotes |
( |
T10333 |
24376-24388 |
JJ |
denotes |
CD8+positive |
T10334 |
24389-24390 |
NN |
denotes |
T |
T10335 |
24391-24402 |
NN |
denotes |
Lymphocytes |
T10336 |
24403-24408 |
NN |
denotes |
cells |
T10337 |
24408-24409 |
-RRB- |
denotes |
) |
T10338 |
24410-24413 |
CC |
denotes |
and |
T10339 |
24414-24421 |
JJ |
denotes |
natural |
T10340 |
24422-24428 |
NN |
denotes |
killer |
T10341 |
24429-24434 |
NN |
denotes |
cells |
T10342 |
24435-24436 |
-LRB- |
denotes |
( |
T10343 |
24436-24440 |
NN |
denotes |
CD57 |
T10344 |
24441-24449 |
JJ |
denotes |
positive |
T10345 |
24450-24452 |
NN |
denotes |
NK |
T10346 |
24453-24458 |
NN |
denotes |
cells |
T10347 |
24458-24459 |
-RRB- |
denotes |
) |
T10348 |
24459-24460 |
-COMMA- |
denotes |
, |
T10349 |
24461-24463 |
RB |
denotes |
as |
T10350 |
24464-24468 |
RB |
denotes |
well |
T10351 |
24469-24471 |
IN |
denotes |
as |
T10352 |
24472-24480 |
NN |
denotes |
dendrite |
T10353 |
24481-24486 |
NN |
denotes |
cells |
T10354 |
24486-24487 |
-COMMA- |
denotes |
, |
T10355 |
24488-24490 |
IN |
denotes |
in |
T10356 |
24491-24497 |
NN |
denotes |
spleen |
T10357 |
24498-24505 |
NN |
denotes |
tissues |
T10358 |
24506-24514 |
VB |
denotes |
compared |
T10359 |
24515-24517 |
TO |
denotes |
to |
T10360 |
24518-24523 |
DT |
denotes |
those |
T10361 |
24524-24531 |
IN |
denotes |
without |
T10362 |
24532-24540 |
NN |
denotes |
melanoma |
T10363 |
24541-24546 |
NN |
denotes |
cells |
T10364 |
24548-24551 |
CC |
denotes |
But |
T10365 |
24552-24555 |
DT |
denotes |
the |
T10366 |
24556-24567 |
NN |
denotes |
lymphocytes |
T10367 |
24568-24570 |
IN |
denotes |
of |
T10368 |
24571-24574 |
DT |
denotes |
the |
T10369 |
24575-24582 |
NN |
denotes |
CCR5−/− |
T10370 |
24583-24587 |
NN |
denotes |
mice |
T10371 |
24588-24591 |
VB |
denotes |
did |
T10372 |
24592-24595 |
RB |
denotes |
not |
T10373 |
24596-24604 |
VB |
denotes |
decrease |
T10374 |
24605-24609 |
WRB |
denotes |
when |
T10375 |
24610-24618 |
VB |
denotes |
injected |
T10376 |
24619-24623 |
IN |
denotes |
with |
T10377 |
24624-24632 |
NN |
denotes |
melanoma |
T10378 |
24633-24638 |
NN |
denotes |
cells |
T10379 |
24640-24645 |
DT |
denotes |
These |
T10380 |
24646-24657 |
NN |
denotes |
differences |
T10381 |
24658-24660 |
IN |
denotes |
of |
T10382 |
24661-24664 |
DT |
denotes |
the |
T10383 |
24665-24671 |
JJ |
denotes |
immune |
T10384 |
24672-24680 |
NN |
denotes |
response |
T10385 |
24681-24688 |
IN |
denotes |
between |
T10386 |
24689-24692 |
DT |
denotes |
the |
T10387 |
24693-24700 |
JJ |
denotes |
CCR5+/+ |
T10388 |
24701-24705 |
NN |
denotes |
mice |
T10389 |
24706-24709 |
CC |
denotes |
and |
T10390 |
24710-24713 |
DT |
denotes |
the |
T10391 |
24714-24721 |
NN |
denotes |
CCR5−/− |
T10392 |
24722-24726 |
NN |
denotes |
mice |
T10393 |
24726-24727 |
-COMMA- |
denotes |
, |
T10394 |
24728-24737 |
VB |
denotes |
involving |
T10395 |
24738-24743 |
NN |
denotes |
tumor |
T10396 |
24744-24750 |
JJ |
denotes |
immune |
T10397 |
24751-24760 |
NN |
denotes |
tolerance |
T10398 |
24760-24761 |
-COMMA- |
denotes |
, |
T10399 |
24762-24765 |
MD |
denotes |
may |
T10400 |
24766-24768 |
VB |
denotes |
be |
T10401 |
24769-24778 |
VB |
denotes |
connected |
T10402 |
24779-24783 |
IN |
denotes |
with |
T10403 |
24784-24787 |
DT |
denotes |
the |
T10404 |
24788-24798 |
NN |
denotes |
inhibition |
T10405 |
24799-24801 |
IN |
denotes |
of |
T10406 |
24802-24808 |
NN |
denotes |
cancer |
T10407 |
24809-24820 |
NN |
denotes |
progression |
T10408 |
24822-24827 |
VB |
denotes |
Taken |
T10409 |
24828-24836 |
RB |
denotes |
together |
T10410 |
24836-24837 |
-COMMA- |
denotes |
, |
T10411 |
24838-24840 |
IN |
denotes |
in |
T10412 |
24841-24844 |
DT |
denotes |
the |
T10413 |
24845-24853 |
NN |
denotes |
cytokine |
T10414 |
24854-24859 |
NN |
denotes |
array |
T10415 |
24860-24870 |
NN |
denotes |
experiment |
T10416 |
24870-24871 |
-COMMA- |
denotes |
, |
T10417 |
24872-24875 |
DT |
denotes |
the |
T10418 |
24876-24881 |
NN |
denotes |
level |
T10419 |
24882-24884 |
IN |
denotes |
of |
T10420 |
24885-24891 |
NN |
denotes |
MIP-1α |
T10421 |
24892-24893 |
-LRB- |
denotes |
( |
T10422 |
24893-24898 |
WDT |
denotes |
which |
T10423 |
24899-24902 |
VB |
denotes |
has |
T10424 |
24903-24904 |
DT |
denotes |
a |
T10425 |
24905-24911 |
JJ |
denotes |
potent |
T10426 |
24912-24920 |
NN |
denotes |
activity |
T10427 |
24921-24923 |
IN |
denotes |
of |
T10428 |
24924-24925 |
NN |
denotes |
T |
T10429 |
24926-24930 |
NN |
denotes |
cell |
T10430 |
24931-24934 |
CC |
denotes |
and |
T10431 |
24935-24936 |
NN |
denotes |
B |
T10432 |
24937-24941 |
NN |
denotes |
cell |
T10433 |
24942-24951 |
NN |
denotes |
migration |
T10434 |
24951-24952 |
-RRB- |
denotes |
) |
T10435 |
24953-24956 |
VB |
denotes |
was |
T10436 |
24957-24966 |
VB |
denotes |
increased |
T10437 |
24967-24969 |
IN |
denotes |
in |
T10438 |
24970-24973 |
DT |
denotes |
the |
T10439 |
24974-24981 |
NN |
denotes |
CCR5−/− |
T10440 |
24982-24986 |
NN |
denotes |
mice |
T10441 |
24987-24995 |
VB |
denotes |
compared |
T10442 |
24996-25000 |
IN |
denotes |
with |
T10443 |
25001-25006 |
DT |
denotes |
those |
T10444 |
25007-25009 |
IN |
denotes |
in |
T10445 |
25010-25013 |
DT |
denotes |
the |
T10446 |
25014-25021 |
JJ |
denotes |
CCR5+/+ |
T10447 |
25022-25026 |
NN |
denotes |
mice |
T10448 |
25028-25032 |
RB |
denotes |
Thus |
T10449 |
25032-25033 |
-COMMA- |
denotes |
, |
T10450 |
25034-25044 |
RB |
denotes |
relatively |
T10451 |
25045-25054 |
VB |
denotes |
increased |
T10452 |
25055-25060 |
NN |
denotes |
tumor |
T10453 |
25061-25071 |
VB |
denotes |
associated |
T10454 |
25072-25081 |
JJ |
denotes |
cytotoxic |
T10455 |
25082-25093 |
NN |
denotes |
lymphocytes |
T10456 |
25094-25099 |
MD |
denotes |
could |
T10457 |
25100-25104 |
VB |
denotes |
play |
T10458 |
25105-25107 |
DT |
denotes |
an |
T10459 |
25108-25117 |
JJ |
denotes |
important |
T10460 |
25118-25122 |
NN |
denotes |
role |
T10461 |
25123-25125 |
IN |
denotes |
in |
T10462 |
25126-25136 |
VB |
denotes |
inhibiting |
T10463 |
25137-25140 |
DT |
denotes |
the |
T10464 |
25141-25146 |
NN |
denotes |
tumor |
T10465 |
25147-25153 |
NN |
denotes |
growth |
T10466 |
25154-25156 |
IN |
denotes |
in |
T10467 |
25157-25164 |
NN |
denotes |
CCR5−/− |
T10468 |
25165-25169 |
NN |
denotes |
mice |
T10469 |
25171-25181 |
NN |
denotes |
Activation |
T10470 |
25182-25184 |
IN |
denotes |
of |
T10471 |
25185-25190 |
NN |
denotes |
NF-κB |
T10472 |
25191-25196 |
MD |
denotes |
could |
T10473 |
25197-25205 |
VB |
denotes |
modulate |
T10474 |
25206-25217 |
JJ |
denotes |
subcellular |
T10475 |
25218-25230 |
NN |
denotes |
localization |
T10476 |
25231-25233 |
IN |
denotes |
of |
T10477 |
25234-25236 |
NN |
denotes |
NK |
T10478 |
25237-25242 |
NN |
denotes |
cells |
T10479 |
25243-25246 |
CC |
denotes |
and |
T10480 |
25247-25259 |
NN |
denotes |
pathogenesis |
T10481 |
25260-25261 |
-LRB- |
denotes |
[ |
T10482 |
25261-25263 |
CD |
denotes |
49 |
T10483 |
25263-25264 |
-RRB- |
denotes |
] |
T10484 |
25266-25276 |
NN |
denotes |
Inhibition |
T10485 |
25277-25279 |
IN |
denotes |
of |
T10486 |
25280-25285 |
NN |
denotes |
NF-κB |
T10487 |
25286-25294 |
NN |
denotes |
activity |
T10488 |
25295-25304 |
VB |
denotes |
prevented |
T10489 |
25305-25307 |
NN |
denotes |
NK |
T10490 |
25308-25312 |
NN |
denotes |
cell |
T10491 |
25313-25322 |
NN |
denotes |
depletion |
T10492 |
25322-25323 |
-COMMA- |
denotes |
, |
T10493 |
25324-25327 |
CC |
denotes |
and |
T10494 |
25328-25332 |
RB |
denotes |
thus |
T10495 |
25333-25342 |
VB |
denotes |
increased |
T10496 |
25343-25353 |
JJ |
denotes |
anti-tumor |
T10497 |
25354-25362 |
NN |
denotes |
activity |
T10498 |
25363-25365 |
IN |
denotes |
by |
T10499 |
25366-25376 |
VB |
denotes |
decreasing |
T10500 |
25377-25381 |
NN |
denotes |
IL-6 |
T10501 |
25382-25392 |
NN |
denotes |
production |
T10502 |
25393-25394 |
-LRB- |
denotes |
[ |
T10503 |
25394-25396 |
CD |
denotes |
50 |
T10504 |
25396-25397 |
-RRB- |
denotes |
] |
T10505 |
25399-25403 |
RB |
denotes |
Thus |
T10506 |
25403-25404 |
-COMMA- |
denotes |
, |
T10507 |
25405-25408 |
DT |
denotes |
the |
T10508 |
25409-25418 |
VB |
denotes |
decreased |
T10509 |
25419-25424 |
NN |
denotes |
NF-κB |
T10510 |
25425-25428 |
CC |
denotes |
and |
T10511 |
25429-25437 |
JJ |
denotes |
elevated |
T10512 |
25438-25444 |
NN |
denotes |
IL-1Ra |
T10513 |
25445-25450 |
MD |
denotes |
could |
T10514 |
25451-25455 |
RB |
denotes |
also |
T10515 |
25456-25458 |
VB |
denotes |
be |
T10516 |
25459-25469 |
VB |
denotes |
associated |
T10517 |
25470-25472 |
IN |
denotes |
in |
T10518 |
25473-25476 |
DT |
denotes |
the |
T10519 |
25477-25489 |
NN |
denotes |
infiltration |
T10520 |
25490-25492 |
IN |
denotes |
of |
T10521 |
25493-25502 |
JJ |
denotes |
cytotoxic |
T10522 |
25503-25514 |
NN |
denotes |
lymphocytes |
T10523 |
25515-25519 |
IN |
denotes |
into |
T10524 |
25520-25525 |
NN |
denotes |
tumor |
T10525 |
25525-25526 |
-COMMA- |
denotes |
, |
T10526 |
25527-25536 |
VB |
denotes |
resulting |
T10527 |
25537-25539 |
IN |
denotes |
in |
T10528 |
25540-25545 |
NN |
denotes |
tumor |
T10529 |
25546-25552 |
NN |
denotes |
growth |
T10530 |
25553-25563 |
NN |
denotes |
inhibition |
T10531 |
25565-25567 |
IN |
denotes |
In |
T10532 |
25568-25576 |
NN |
denotes |
contrast |
T10533 |
25576-25577 |
-COMMA- |
denotes |
, |
T10534 |
25578-25583 |
NN |
denotes |
IL-23 |
T10535 |
25583-25584 |
-COMMA- |
denotes |
, |
T10536 |
25585-25586 |
DT |
denotes |
a |
T10537 |
25587-25592 |
NN |
denotes |
tumor |
T10538 |
25593-25599 |
NN |
denotes |
growth |
T10539 |
25600-25609 |
VB |
denotes |
promoting |
T10540 |
25610-25618 |
NN |
denotes |
cytokine |
T10541 |
25618-25619 |
-COMMA- |
denotes |
, |
T10542 |
25620-25629 |
VB |
denotes |
increased |
T10543 |
25630-25635 |
NN |
denotes |
NF-κB |
T10544 |
25636-25639 |
CC |
denotes |
and |
T10545 |
25640-25646 |
JJ |
denotes |
immune |
T10546 |
25647-25651 |
NN |
denotes |
cell |
T10547 |
25652-25664 |
NN |
denotes |
infiltration |
T10548 |
25665-25667 |
IN |
denotes |
in |
T10549 |
25668-25672 |
JJ |
denotes |
oral |
T10550 |
25673-25678 |
NN |
denotes |
tumor |
T10551 |
25679-25680 |
-LRB- |
denotes |
[ |
T10552 |
25680-25682 |
CD |
denotes |
51 |
T10553 |
25682-25683 |
-RRB- |
denotes |
] |
T10554 |
25685-25690 |
DT |
denotes |
These |
T10555 |
25691-25695 |
NN |
denotes |
data |
T10556 |
25696-25704 |
VB |
denotes |
indicate |
T10557 |
25705-25709 |
IN |
denotes |
that |
T10558 |
25710-25715 |
NN |
denotes |
NF-κB |
T10559 |
25716-25721 |
MD |
denotes |
could |
T10560 |
25722-25724 |
VB |
denotes |
be |
T10561 |
25725-25733 |
VB |
denotes |
involved |
T10562 |
25734-25736 |
IN |
denotes |
in |
T10563 |
25737-25740 |
DT |
denotes |
the |
T10564 |
25741-25749 |
NN |
denotes |
cytokine |
T10565 |
25750-25758 |
VB |
denotes |
mediated |
T10566 |
25759-25769 |
JJ |
denotes |
anti-tumor |
T10567 |
25770-25780 |
NN |
denotes |
activities |
T10568 |
25781-25783 |
IN |
denotes |
of |
T10569 |
25784-25790 |
JJ |
denotes |
immune |
T10570 |
25791-25796 |
NN |
denotes |
cells |
T10571 |
25798-25800 |
PRP |
denotes |
It |
T10572 |
25801-25803 |
VB |
denotes |
is |
T10573 |
25804-25808 |
RB |
denotes |
also |
T10574 |
25809-25819 |
JJ |
denotes |
noteworthy |
T10575 |
25820-25824 |
IN |
denotes |
that |
T10576 |
25825-25831 |
NN |
denotes |
IL-1Ra |
T10577 |
25832-25841 |
VB |
denotes |
inhibited |
T10578 |
25842-25850 |
NN |
denotes |
melanoma |
T10579 |
25851-25856 |
NN |
denotes |
tumor |
T10580 |
25857-25863 |
NN |
denotes |
growth |
T10581 |
25864-25866 |
IN |
denotes |
by |
T10582 |
25867-25877 |
VB |
denotes |
increasing |
T10583 |
25878-25881 |
DT |
denotes |
the |
T10584 |
25882-25888 |
NN |
denotes |
number |
T10585 |
25889-25891 |
IN |
denotes |
of |
T10586 |
25892-25899 |
JJ |
denotes |
myeloid |
T10587 |
25900-25910 |
NN |
denotes |
suppressor |
T10588 |
25911-25916 |
NN |
denotes |
cells |
T10589 |
25917-25919 |
IN |
denotes |
in |
T10590 |
25920-25925 |
NN |
denotes |
tumor |
T10591 |
25926-25927 |
-LRB- |
denotes |
[ |
T10592 |
25927-25929 |
CD |
denotes |
25 |
T10593 |
25929-25930 |
-RRB- |
denotes |
] |
T10594 |
25932-25935 |
DT |
denotes |
The |
T10595 |
25936-25962 |
JJ |
denotes |
3-methylcholatrene-induced |
T10596 |
25963-25968 |
NN |
denotes |
tumor |
T10597 |
25969-25978 |
NN |
denotes |
incidence |
T10598 |
25979-25982 |
VB |
denotes |
was |
T10599 |
25983-25990 |
VB |
denotes |
reduced |
T10600 |
25991-25993 |
IN |
denotes |
in |
T10601 |
25994-25999 |
NN |
denotes |
IL-1α |
T10602 |
26000-26008 |
NN |
denotes |
knockout |
T10603 |
26009-26013 |
NN |
denotes |
mice |
T10604 |
26013-26014 |
-COMMA- |
denotes |
, |
T10605 |
26015-26018 |
CC |
denotes |
but |
T10606 |
26019-26028 |
VB |
denotes |
increased |
T10607 |
26029-26031 |
IN |
denotes |
in |
T10608 |
26032-26038 |
NN |
denotes |
IL-1Ra |
T10609 |
26039-26043 |
NN |
denotes |
mice |
T10610 |
26044-26048 |
IN |
denotes |
with |
T10611 |
26049-26060 |
JJ |
denotes |
concomitant |
T10612 |
26061-26071 |
NN |
denotes |
maturation |
T10613 |
26072-26074 |
IN |
denotes |
of |
T10614 |
26075-26077 |
NN |
denotes |
NK |
T10615 |
26078-26083 |
NN |
denotes |
cells |
T10616 |
26084-26087 |
CC |
denotes |
and |
T10617 |
26088-26098 |
JJ |
denotes |
anti-tumor |
T10618 |
26099-26107 |
NN |
denotes |
immunity |
T10619 |
26108-26109 |
-LRB- |
denotes |
[ |
T10620 |
26109-26111 |
CD |
denotes |
52 |
T10621 |
26111-26112 |
-RRB- |
denotes |
] |
T10622 |
26114-26119 |
DT |
denotes |
These |
T10623 |
26120-26124 |
NN |
denotes |
data |
T10624 |
26125-26133 |
VB |
denotes |
indicate |
T10625 |
26134-26138 |
IN |
denotes |
that |
T10626 |
26139-26142 |
DT |
denotes |
the |
T10627 |
26143-26151 |
NN |
denotes |
decrease |
T10628 |
26152-26154 |
IN |
denotes |
of |
T10629 |
26155-26160 |
NN |
denotes |
NF-κB |
T10630 |
26160-26161 |
-COMMA- |
denotes |
, |
T10631 |
26162-26165 |
CC |
denotes |
and |
T10632 |
26166-26170 |
RB |
denotes |
thus |
T10633 |
26171-26179 |
NN |
denotes |
increase |
T10634 |
26180-26182 |
IN |
denotes |
of |
T10635 |
26183-26189 |
NN |
denotes |
IL-1Ra |
T10636 |
26190-26195 |
MD |
denotes |
could |
T10637 |
26196-26198 |
VB |
denotes |
be |
T10638 |
26199-26210 |
JJ |
denotes |
significant |
T10639 |
26211-26213 |
IN |
denotes |
in |
T10640 |
26214-26219 |
NN |
denotes |
tumor |
T10641 |
26220-26226 |
NN |
denotes |
growth |
T10642 |
26227-26237 |
NN |
denotes |
inhibition |
T10643 |
26238-26240 |
IN |
denotes |
of |
T10644 |
26241-26248 |
NN |
denotes |
CCR5−/− |
T10645 |
26249-26253 |
NN |
denotes |
mice |
T10646 |
26255-26258 |
PRP-DOLLAR- |
denotes |
Our |
T10647 |
26259-26263 |
NN |
denotes |
data |
T10648 |
26264-26268 |
RB |
denotes |
thus |
T10649 |
26269-26273 |
VB |
denotes |
show |
T10650 |
26274-26285 |
JJ |
denotes |
significant |
T10651 |
26286-26294 |
JJ |
denotes |
clinical |
T10652 |
26295-26307 |
NN |
denotes |
implications |
T10653 |
26308-26310 |
IN |
denotes |
of |
T10654 |
26311-26315 |
NN |
denotes |
CCR5 |
T10655 |
26315-26316 |
-COMMA- |
denotes |
, |
T10656 |
26317-26324 |
IN |
denotes |
because |
T10657 |
26325-26329 |
NN |
denotes |
CCR5 |
T10658 |
26330-26332 |
VB |
denotes |
is |
T10659 |
26333-26334 |
DT |
denotes |
a |
T10660 |
26335-26336 |
NN |
denotes |
G |
T10661 |
26337-26352 |
VB |
denotes |
protein–coupled |
T10662 |
26353-26361 |
NN |
denotes |
receptor |
T10663 |
26362-26365 |
CC |
denotes |
and |
T10664 |
26366-26368 |
PRP |
denotes |
it |
T10665 |
26369-26371 |
VB |
denotes |
is |
T10666 |
26372-26380 |
JJ |
denotes |
amenable |
T10667 |
26381-26383 |
TO |
denotes |
to |
T10668 |
26384-26387 |
VB |
denotes |
use |
T10669 |
26388-26390 |
IN |
denotes |
as |
T10670 |
26391-26392 |
DT |
denotes |
a |
T10671 |
26393-26398 |
JJ |
denotes |
small |
T10672 |
26399-26407 |
NN |
denotes |
molecule |
T10673 |
26408-26411 |
IN |
denotes |
for |
T10674 |
26412-26415 |
DT |
denotes |
the |
T10675 |
26416-26426 |
NN |
denotes |
inhibition |
T10676 |
26427-26429 |
IN |
denotes |
of |
T10677 |
26430-26434 |
NN |
denotes |
CCR5 |
T10678 |
26436-26443 |
JJ |
denotes |
Several |
T10679 |
26444-26448 |
JJ |
denotes |
such |
T10680 |
26449-26458 |
NN |
denotes |
compounds |
T10681 |
26459-26463 |
VB |
denotes |
have |
T10682 |
26464-26471 |
RB |
denotes |
already |
T10683 |
26472-26476 |
VB |
denotes |
been |
T10684 |
26477-26482 |
VB |
denotes |
shown |
T10685 |
26483-26485 |
TO |
denotes |
to |
T10686 |
26486-26488 |
VB |
denotes |
be |
T10687 |
26489-26493 |
JJ |
denotes |
safe |
T10688 |
26494-26496 |
IN |
denotes |
in |
T10689 |
26497-26505 |
JJ |
denotes |
clinical |
T10690 |
26506-26512 |
NN |
denotes |
trials |
T10691 |
26513-26516 |
IN |
denotes |
for |
T10692 |
26517-26520 |
NN |
denotes |
use |
T10693 |
26521-26523 |
IN |
denotes |
in |
T10694 |
26524-26531 |
JJ |
denotes |
certain |
T10695 |
26532-26540 |
NN |
denotes |
diseases |
T10696 |
26541-26545 |
JJ |
denotes |
such |
T10697 |
26546-26548 |
IN |
denotes |
as |
T10698 |
26549-26552 |
NN |
denotes |
HIV |
T10699 |
26553-26554 |
-LRB- |
denotes |
[ |
T10700 |
26554-26556 |
CD |
denotes |
53 |
T10701 |
26556-26557 |
-RRB- |
denotes |
] |
T10702 |
26559-26563 |
RB |
denotes |
Thus |
T10703 |
26563-26564 |
-COMMA- |
denotes |
, |
T10704 |
26565-26567 |
PRP |
denotes |
we |
T10705 |
26568-26575 |
VB |
denotes |
believe |
T10706 |
26576-26580 |
NN |
denotes |
CCR5 |
T10707 |
26581-26583 |
VB |
denotes |
is |
T10708 |
26584-26585 |
DT |
denotes |
a |
T10709 |
26586-26592 |
NN |
denotes |
cancer |
T10710 |
26593-26599 |
NN |
denotes |
target |
T10711 |
26600-26604 |
WDT |
denotes |
that |
T10712 |
26605-26613 |
VB |
denotes |
warrants |
T10713 |
26614-26623 |
JJ |
denotes |
continued |
T10714 |
26624-26637 |
NN |
denotes |
investigation |
T10715 |
26639-26641 |
IN |
denotes |
In |
T10716 |
26642-26649 |
NN |
denotes |
summary |
T10717 |
26649-26650 |
-COMMA- |
denotes |
, |
T10718 |
26651-26655 |
DT |
denotes |
this |
T10719 |
26656-26661 |
NN |
denotes |
study |
T10720 |
26662-26668 |
VB |
denotes |
showed |
T10721 |
26669-26673 |
IN |
denotes |
that |
T10722 |
26674-26682 |
NN |
denotes |
melanoma |
T10723 |
26683-26688 |
NN |
denotes |
cells |
T10724 |
26689-26695 |
NN |
denotes |
growth |
T10725 |
26696-26699 |
VB |
denotes |
was |
T10726 |
26700-26709 |
VB |
denotes |
inhibited |
T10727 |
26710-26713 |
IN |
denotes |
via |
T10728 |
26714-26724 |
NN |
denotes |
modulation |
T10729 |
26725-26727 |
IN |
denotes |
of |
T10730 |
26728-26740 |
NN |
denotes |
NF-κB/IL-1Ra |
T10731 |
26741-26749 |
NN |
denotes |
pathways |
T10732 |
26750-26752 |
IN |
denotes |
in |
T10733 |
26753-26760 |
NN |
denotes |
CCR5−/− |
T10734 |
26761-26765 |
NN |
denotes |
mice |
T13208 |
26791-26797 |
NNP |
denotes |
Ethics |
T13209 |
26798-26807 |
NNP |
denotes |
Statement |
T13210 |
26808-26811 |
DT |
denotes |
All |
T13211 |
26812-26823 |
NN |
denotes |
experiments |
T13212 |
26824-26828 |
VB |
denotes |
were |
T13213 |
26829-26837 |
VB |
denotes |
approved |
T13214 |
26838-26841 |
CC |
denotes |
and |
T13215 |
26842-26849 |
VB |
denotes |
carried |
T13216 |
26850-26853 |
RP |
denotes |
out |
T13217 |
26854-26863 |
VB |
denotes |
according |
T13218 |
26864-26866 |
TO |
denotes |
to |
T13219 |
26867-26870 |
DT |
denotes |
the |
T13220 |
26871-26876 |
NNP |
denotes |
Guide |
T13221 |
26877-26880 |
IN |
denotes |
for |
T13222 |
26881-26884 |
DT |
denotes |
the |
T13223 |
26885-26889 |
NNP |
denotes |
Care |
T13224 |
26890-26893 |
CC |
denotes |
and |
T13225 |
26894-26897 |
NNP |
denotes |
Use |
T13226 |
26898-26900 |
IN |
denotes |
of |
T13227 |
26901-26908 |
NNP |
denotes |
Animals |
T13228 |
26909-26910 |
-LRB- |
denotes |
[ |
T13229 |
26910-26916 |
NNP |
denotes |
Animal |
T13230 |
26917-26921 |
NNP |
denotes |
Care |
T13231 |
26922-26931 |
NNP |
denotes |
Committee |
T13232 |
26932-26934 |
IN |
denotes |
of |
T13233 |
26935-26943 |
NNP |
denotes |
Chungbuk |
T13234 |
26944-26952 |
NNP |
denotes |
National |
T13235 |
26953-26963 |
NNP |
denotes |
University |
T13236 |
26963-26964 |
-COMMA- |
denotes |
, |
T13237 |
26965-26970 |
NNP |
denotes |
Korea |
T13238 |
26971-26972 |
-LRB- |
denotes |
( |
T13239 |
26972-26989 |
NN |
denotes |
CBNUA-045-0902-01 |
T13240 |
26989-26990 |
-RRB- |
denotes |
) |
T13241 |
26990-26991 |
-RRB- |
denotes |
] |
T13343 |
26994-27001 |
NN |
denotes |
Animals |
T13344 |
27002-27005 |
DT |
denotes |
The |
T13345 |
27006-27010 |
NN |
denotes |
CCR5 |
T13346 |
27011-27015 |
JJ |
denotes |
wild |
T13347 |
27016-27020 |
NN |
denotes |
type |
T13348 |
27021-27022 |
-LRB- |
denotes |
( |
T13349 |
27022-27029 |
NN |
denotes |
CCR5+/+ |
T13350 |
27029-27030 |
-RRB- |
denotes |
) |
T13351 |
27031-27034 |
CC |
denotes |
and |
T13352 |
27035-27039 |
NN |
denotes |
CCR5 |
T13353 |
27040-27048 |
NN |
denotes |
knockout |
T13354 |
27049-27050 |
-LRB- |
denotes |
( |
T13355 |
27050-27057 |
NN |
denotes |
CCR5−/− |
T13356 |
27057-27058 |
-RRB- |
denotes |
) |
T13357 |
27059-27063 |
NN |
denotes |
mice |
T13358 |
27064-27068 |
VB |
denotes |
were |
T13359 |
27069-27078 |
VB |
denotes |
purchased |
T13360 |
27079-27083 |
IN |
denotes |
from |
T13361 |
27084-27087 |
DT |
denotes |
The |
T13362 |
27088-27095 |
NNP |
denotes |
Jackson |
T13363 |
27096-27106 |
NNP |
denotes |
Laboratory |
T13364 |
27107-27108 |
-LRB- |
denotes |
( |
T13365 |
27108-27111 |
NNP |
denotes |
Bar |
T13366 |
27112-27118 |
NNP |
denotes |
Harbor |
T13367 |
27118-27119 |
-COMMA- |
denotes |
, |
T13368 |
27120-27125 |
NNP |
denotes |
Maine |
T13369 |
27126-27131 |
CD |
denotes |
04609 |
T13370 |
27132-27135 |
NNP |
denotes |
USA |
T13371 |
27135-27136 |
-RRB- |
denotes |
) |
T13372 |
27138-27141 |
DT |
denotes |
The |
T13373 |
27142-27146 |
NN |
denotes |
mice |
T13374 |
27147-27151 |
VB |
denotes |
were |
T13375 |
27152-27158 |
VB |
denotes |
housed |
T13376 |
27159-27162 |
CC |
denotes |
and |
T13377 |
27163-27167 |
VB |
denotes |
bred |
T13378 |
27168-27173 |
IN |
denotes |
under |
T13379 |
27174-27182 |
JJ |
denotes |
specific |
T13380 |
27183-27191 |
NN |
denotes |
pathogen |
T13381 |
27192-27196 |
JJ |
denotes |
free |
T13382 |
27197-27207 |
NN |
denotes |
conditions |
T13383 |
27208-27210 |
IN |
denotes |
at |
T13384 |
27211-27214 |
DT |
denotes |
the |
T13385 |
27215-27225 |
NNP |
denotes |
Laboratory |
T13386 |
27226-27232 |
NNP |
denotes |
Animal |
T13387 |
27233-27241 |
NNP |
denotes |
Research |
T13388 |
27242-27248 |
NNP |
denotes |
Center |
T13389 |
27249-27251 |
IN |
denotes |
of |
T13390 |
27252-27260 |
NNP |
denotes |
Chungbuk |
T13391 |
27261-27269 |
NNP |
denotes |
National |
T13392 |
27270-27280 |
NNP |
denotes |
University |
T13393 |
27280-27281 |
-COMMA- |
denotes |
, |
T13394 |
27282-27288 |
NNP |
denotes |
Korea. |
T13395 |
27289-27292 |
DT |
denotes |
The |
T13396 |
27293-27297 |
NN |
denotes |
mice |
T13397 |
27298-27299 |
-LRB- |
denotes |
( |
T13398 |
27299-27309 |
NN |
denotes |
n = 4/cage |
T13399 |
27309-27310 |
-RRB- |
denotes |
) |
T13400 |
27311-27315 |
VB |
denotes |
were |
T13401 |
27316-27326 |
VB |
denotes |
maintained |
T13402 |
27327-27329 |
IN |
denotes |
in |
T13403 |
27330-27331 |
DT |
denotes |
a |
T13404 |
27332-27336 |
NN |
denotes |
room |
T13405 |
27337-27341 |
IN |
denotes |
with |
T13406 |
27342-27343 |
DT |
denotes |
a |
T13407 |
27344-27352 |
JJ |
denotes |
constant |
T13408 |
27353-27364 |
NN |
denotes |
temperature |
T13409 |
27365-27367 |
IN |
denotes |
of |
T13410 |
27368-27374 |
NN |
denotes |
22±1°C |
T13411 |
27374-27375 |
-COMMA- |
denotes |
, |
T13412 |
27376-27384 |
JJ |
denotes |
relative |
T13413 |
27385-27393 |
NN |
denotes |
humidity |
T13414 |
27394-27396 |
IN |
denotes |
of |
T13415 |
27397-27402 |
CD |
denotes |
55±10 |
T13416 |
27402-27403 |
NN |
denotes |
% |
T13417 |
27403-27404 |
-COMMA- |
denotes |
, |
T13418 |
27405-27408 |
CC |
denotes |
and |
T13419 |
27409-27413 |
JJ |
denotes |
12-h |
T13420 |
27414-27424 |
NN |
denotes |
light/dark |
T13421 |
27425-27430 |
NN |
denotes |
cycle |
T13422 |
27430-27431 |
-COMMA- |
denotes |
, |
T13423 |
27432-27435 |
CC |
denotes |
and |
T13424 |
27436-27439 |
VB |
denotes |
fed |
T13425 |
27440-27448 |
JJ |
denotes |
standard |
T13426 |
27449-27455 |
NN |
denotes |
rodent |
T13427 |
27456-27460 |
NN |
denotes |
chow |
T13428 |
27461-27462 |
-LRB- |
denotes |
( |
T13429 |
27462-27469 |
NNP |
denotes |
Samyang |
T13430 |
27469-27470 |
-COMMA- |
denotes |
, |
T13431 |
27471-27476 |
NNP |
denotes |
Korea |
T13432 |
27476-27477 |
-RRB- |
denotes |
) |
T13433 |
27478-27481 |
CC |
denotes |
and |
T13434 |
27482-27490 |
VB |
denotes |
purified |
T13435 |
27491-27494 |
NN |
denotes |
tap |
T13436 |
27495-27500 |
NN |
denotes |
water |
T13437 |
27501-27503 |
NN |
denotes |
ad |
T13438 |
27504-27511 |
NN |
denotes |
libitum |
T13439 |
27513-27516 |
DT |
denotes |
The |
T13440 |
27517-27524 |
JJ |
denotes |
CCR5+/+ |
T13441 |
27525-27529 |
NN |
denotes |
mice |
T13442 |
27530-27531 |
-LRB- |
denotes |
( |
T13443 |
27531-27537 |
NN |
denotes |
n = 20 |
T13444 |
27537-27538 |
-RRB- |
denotes |
) |
T13445 |
27539-27542 |
CC |
denotes |
and |
T13446 |
27543-27550 |
NN |
denotes |
CCR5−/− |
T13447 |
27551-27555 |
NN |
denotes |
mice |
T13448 |
27556-27557 |
-LRB- |
denotes |
( |
T13449 |
27557-27563 |
NN |
denotes |
n = 20 |
T13450 |
27563-27564 |
-RRB- |
denotes |
) |
T13451 |
27564-27565 |
-COMMA- |
denotes |
, |
T13452 |
27566-27570 |
WDT |
denotes |
that |
T13453 |
27571-27575 |
VB |
denotes |
were |
T13454 |
27576-27580 |
VB |
denotes |
used |
T13455 |
27580-27581 |
-COMMA- |
denotes |
, |
T13456 |
27582-27585 |
VB |
denotes |
had |
T13457 |
27586-27593 |
VB |
denotes |
matched |
T13458 |
27594-27598 |
NN |
denotes |
ages |
T13459 |
27599-27600 |
-LRB- |
denotes |
( |
T13460 |
27600-27605 |
CD |
denotes |
10–11 |
T13461 |
27606-27611 |
NN |
denotes |
weeks |
T13462 |
27612-27615 |
JJ |
denotes |
old |
T13463 |
27615-27616 |
-RRB- |
denotes |
) |
T13464 |
27617-27620 |
CC |
denotes |
and |
T13465 |
27621-27628 |
NN |
denotes |
weights |
T13466 |
27629-27630 |
-LRB- |
denotes |
( |
T13467 |
27630-27635 |
CD |
denotes |
16–19 |
T13468 |
27636-27637 |
NN |
denotes |
g |
T13469 |
27637-27638 |
-RRB- |
denotes |
) |
T13470 |
27640-27647 |
NN |
denotes |
Control |
T13471 |
27648-27652 |
NN |
denotes |
mice |
T13472 |
27653-27654 |
-LRB- |
denotes |
( |
T13473 |
27654-27664 |
NN |
denotes |
B6129PF2/J |
T13474 |
27664-27665 |
-RRB- |
denotes |
) |
T13475 |
27666-27670 |
VB |
denotes |
were |
T13476 |
27671-27673 |
NN |
denotes |
F2 |
T13477 |
27674-27680 |
JJ |
denotes |
hybrid |
T13478 |
27681-27685 |
NN |
denotes |
mice |
T13479 |
27686-27690 |
IN |
denotes |
from |
T13480 |
27691-27694 |
DT |
denotes |
the |
T13481 |
27695-27708 |
NN |
denotes |
C57BL/6J-AW-J |
T13482 |
27709-27712 |
CC |
denotes |
and |
T13483 |
27713-27720 |
NN |
denotes |
129P3/J |
T13484 |
27721-27729 |
JJ |
denotes |
parental |
T13485 |
27730-27737 |
NN |
denotes |
strains |
T13486 |
27739-27743 |
NN |
denotes |
CCR5 |
T13487 |
27744-27748 |
NN |
denotes |
mice |
T13488 |
27749-27750 |
-LRB- |
denotes |
( |
T13489 |
27750-27752 |
NN |
denotes |
B6 |
T13490 |
27752-27753 |
-COMMA- |
denotes |
, |
T13491 |
27754-27772 |
NN |
denotes |
129P2-Ccr5tm1Kuz/J |
T13492 |
27772-27773 |
-RRB- |
denotes |
) |
T13493 |
27774-27778 |
VB |
denotes |
have |
T13494 |
27779-27782 |
DT |
denotes |
the |
T13495 |
27783-27789 |
JJ |
denotes |
entire |
T13496 |
27790-27796 |
VB |
denotes |
coding |
T13497 |
27797-27803 |
NN |
denotes |
region |
T13498 |
27804-27806 |
IN |
denotes |
of |
T13499 |
27807-27810 |
DT |
denotes |
the |
T13500 |
27811-27815 |
NN |
denotes |
CCR5 |
T13501 |
27816-27820 |
NN |
denotes |
gene |
T13502 |
27821-27828 |
VB |
denotes |
deleted |
T13503 |
27829-27833 |
IN |
denotes |
from |
T13504 |
27834-27837 |
DT |
denotes |
the |
T13505 |
27838-27846 |
JJ |
denotes |
parental |
T13506 |
27847-27854 |
NN |
denotes |
strains |
T13507 |
27854-27855 |
-COMMA- |
denotes |
, |
T13508 |
27856-27858 |
NN |
denotes |
B6 |
T13509 |
27858-27859 |
-COLON- |
denotes |
; |
T13510 |
27859-27875 |
NN |
denotes |
129P2-Ccr5tm1kuz |
T13511 |
27876-27879 |
CC |
denotes |
and |
T13512 |
27880-27882 |
NN |
denotes |
B6 |
T13513 |
27882-27883 |
-COLON- |
denotes |
; |
T13514 |
27883-27901 |
NN |
denotes |
129P2-Cmkbr5tm1Kuz |
T13814 |
27904-27909 |
NN |
denotes |
Tumor |
T13815 |
27910-27921 |
NN |
denotes |
Inoculation |
T13816 |
27922-27925 |
CC |
denotes |
and |
T13817 |
27926-27931 |
NN |
denotes |
Tumor |
T13818 |
27932-27942 |
NN |
denotes |
Monitoring |
T13819 |
27943-27946 |
NN |
denotes |
B16 |
T13820 |
27947-27955 |
NN |
denotes |
melanoma |
T13821 |
27956-27961 |
NN |
denotes |
cells |
T13822 |
27962-27966 |
VB |
denotes |
were |
T13823 |
27967-27975 |
VB |
denotes |
injected |
T13824 |
27976-27990 |
RB |
denotes |
subcutaneously |
T13825 |
27991-27992 |
-LRB- |
denotes |
[ |
T13826 |
27992-27997 |
CD |
denotes |
5×105 |
T13827 |
27998-28003 |
NN |
denotes |
tumor |
T13828 |
28004-28009 |
NN |
denotes |
cells |
T13829 |
28010-28012 |
IN |
denotes |
in |
T13830 |
28013-28016 |
CD |
denotes |
0.1 |
T13831 |
28017-28019 |
NN |
denotes |
ml |
T13832 |
28020-28029 |
NN |
denotes |
Phosphate |
T13833 |
28030-28038 |
VB |
denotes |
buffered |
T13834 |
28039-28045 |
NN |
denotes |
saline |
T13835 |
28045-28046 |
-LRB- |
denotes |
( |
T13836 |
28046-28049 |
NN |
denotes |
PBS |
T13837 |
28049-28050 |
-RRB- |
denotes |
) |
T13838 |
28050-28057 |
JJ |
denotes |
/animal |
T13839 |
28057-28058 |
-RRB- |
denotes |
] |
T13840 |
28059-28064 |
VB |
denotes |
using |
T13841 |
28065-28066 |
DT |
denotes |
a |
T13842 |
28067-28069 |
CD |
denotes |
27 |
T13843 |
28070-28071 |
NN |
denotes |
G |
T13844 |
28072-28078 |
NN |
denotes |
needle |
T13845 |
28079-28083 |
IN |
denotes |
into |
T13846 |
28084-28087 |
DT |
denotes |
the |
T13847 |
28088-28099 |
JJ |
denotes |
right-lower |
T13848 |
28100-28106 |
NN |
denotes |
flanks |
T13849 |
28107-28109 |
IN |
denotes |
of |
T13850 |
28110-28113 |
DT |
denotes |
the |
T13851 |
28114-28121 |
NN |
denotes |
carrier |
T13852 |
28122-28126 |
NN |
denotes |
mice |
T13853 |
28127-28129 |
IN |
denotes |
as |
T13854 |
28130-28140 |
RB |
denotes |
previously |
T13855 |
28141-28150 |
VB |
denotes |
described |
T13856 |
28151-28152 |
-LRB- |
denotes |
[ |
T13857 |
28152-28154 |
CD |
denotes |
54 |
T13858 |
28154-28155 |
-RRB- |
denotes |
] |
T13859 |
28157-28160 |
DT |
denotes |
The |
T13860 |
28161-28165 |
NN |
denotes |
body |
T13861 |
28166-28173 |
NN |
denotes |
weights |
T13862 |
28174-28177 |
CC |
denotes |
and |
T13863 |
28178-28183 |
NN |
denotes |
tumor |
T13864 |
28184-28191 |
NN |
denotes |
volumes |
T13865 |
28192-28194 |
IN |
denotes |
of |
T13866 |
28195-28198 |
DT |
denotes |
the |
T13867 |
28199-28206 |
NN |
denotes |
animals |
T13868 |
28207-28211 |
VB |
denotes |
were |
T13869 |
28212-28221 |
VB |
denotes |
monitored |
T13870 |
28222-28227 |
RB |
denotes |
twice |
T13871 |
28228-28234 |
RB |
denotes |
weekly |
T13872 |
28236-28239 |
DT |
denotes |
The |
T13873 |
28240-28245 |
NN |
denotes |
tumor |
T13874 |
28246-28253 |
NN |
denotes |
volumes |
T13875 |
28254-28258 |
VB |
denotes |
were |
T13876 |
28259-28267 |
VB |
denotes |
measured |
T13877 |
28268-28272 |
IN |
denotes |
with |
T13878 |
28273-28280 |
JJ |
denotes |
Vernier |
T13879 |
28281-28289 |
NN |
denotes |
calipers |
T13880 |
28290-28293 |
CC |
denotes |
and |
T13881 |
28294-28304 |
VB |
denotes |
calculated |
T13882 |
28305-28310 |
VB |
denotes |
using |
T13883 |
28311-28314 |
DT |
denotes |
the |
T13884 |
28315-28324 |
VB |
denotes |
following |
T13885 |
28325-28332 |
NN |
denotes |
formula |
T13886 |
28332-28333 |
-COLON- |
denotes |
: |
T13887 |
28334-28335 |
-LRB- |
denotes |
( |
T13888 |
28335-28339 |
NN |
denotes |
A×B2 |
T13889 |
28339-28340 |
-RRB- |
denotes |
) |
T13890 |
28340-28342 |
CD |
denotes |
/2 |
T13891 |
28342-28343 |
-COMMA- |
denotes |
, |
T13892 |
28344-28349 |
WRB |
denotes |
where |
T13893 |
28350-28351 |
NN |
denotes |
A |
T13894 |
28352-28354 |
VB |
denotes |
is |
T13895 |
28355-28358 |
DT |
denotes |
the |
T13896 |
28359-28365 |
JJ |
denotes |
larger |
T13897 |
28366-28369 |
CC |
denotes |
and |
T13898 |
28370-28371 |
NN |
denotes |
B |
T13899 |
28372-28374 |
VB |
denotes |
is |
T13900 |
28375-28378 |
DT |
denotes |
the |
T13901 |
28379-28386 |
JJ |
denotes |
smaller |
T13902 |
28387-28389 |
IN |
denotes |
of |
T13903 |
28390-28393 |
DT |
denotes |
the |
T13904 |
28394-28397 |
CD |
denotes |
two |
T13905 |
28398-28408 |
NN |
denotes |
dimensions |
T13906 |
28410-28412 |
IN |
denotes |
At |
T13907 |
28413-28416 |
DT |
denotes |
the |
T13908 |
28417-28420 |
NN |
denotes |
end |
T13909 |
28421-28423 |
IN |
denotes |
of |
T13910 |
28424-28427 |
DT |
denotes |
the |
T13911 |
28428-28438 |
NN |
denotes |
experiment |
T13912 |
28438-28439 |
-COMMA- |
denotes |
, |
T13913 |
28440-28443 |
DT |
denotes |
the |
T13914 |
28444-28451 |
NN |
denotes |
animals |
T13915 |
28452-28456 |
VB |
denotes |
were |
T13916 |
28457-28467 |
VB |
denotes |
sacrificed |
T13917 |
28469-28472 |
DT |
denotes |
The |
T13918 |
28473-28479 |
NN |
denotes |
tumors |
T13919 |
28480-28484 |
VB |
denotes |
were |
T13920 |
28485-28494 |
VB |
denotes |
separated |
T13921 |
28495-28499 |
IN |
denotes |
from |
T13922 |
28500-28503 |
DT |
denotes |
the |
T13923 |
28504-28515 |
VB |
denotes |
surrounding |
T13924 |
28516-28523 |
NN |
denotes |
muscles |
T13925 |
28524-28527 |
CC |
denotes |
and |
T13926 |
28528-28534 |
NN |
denotes |
dermis |
T14102 |
28537-28544 |
NNP |
denotes |
Western |
T14103 |
28545-28553 |
NNP |
denotes |
Blotting |
T14104 |
28554-28559 |
NN |
denotes |
Tumor |
T14105 |
28560-28567 |
NN |
denotes |
tissues |
T14106 |
28568-28572 |
VB |
denotes |
were |
T14107 |
28573-28584 |
VB |
denotes |
homogenized |
T14108 |
28585-28589 |
IN |
denotes |
with |
T14109 |
28590-28597 |
NN |
denotes |
protein |
T14110 |
28598-28608 |
NN |
denotes |
extraction |
T14111 |
28609-28617 |
NN |
denotes |
solution |
T14112 |
28618-28619 |
-LRB- |
denotes |
( |
T14113 |
28619-28629 |
NN |
denotes |
PRO-PREPTM |
T14114 |
28629-28630 |
-COMMA- |
denotes |
, |
T14115 |
28631-28637 |
NNP |
denotes |
Intron |
T14116 |
28638-28651 |
NNP |
denotes |
Biotechnology |
T14117 |
28651-28652 |
-COMMA- |
denotes |
, |
T14118 |
28653-28658 |
NNP |
denotes |
Seoul |
T14119 |
28658-28659 |
-COMMA- |
denotes |
, |
T14120 |
28660-28665 |
NNP |
denotes |
Korea |
T14121 |
28665-28666 |
-RRB- |
denotes |
) |
T14122 |
28666-28667 |
-COMMA- |
denotes |
, |
T14123 |
28668-28671 |
CC |
denotes |
and |
T14124 |
28672-28677 |
VB |
denotes |
lysed |
T14125 |
28678-28680 |
IN |
denotes |
by |
T14126 |
28681-28683 |
CD |
denotes |
60 |
T14127 |
28684-28687 |
NN |
denotes |
min |
T14128 |
28688-28698 |
NN |
denotes |
incubation |
T14129 |
28699-28701 |
IN |
denotes |
on |
T14130 |
28702-28705 |
NN |
denotes |
ice |
T14131 |
28707-28710 |
DT |
denotes |
The |
T14132 |
28711-28717 |
NN |
denotes |
tissue |
T14133 |
28718-28724 |
NN |
denotes |
lysate |
T14134 |
28725-28736 |
VB |
denotes |
centrifuged |
T14135 |
28737-28739 |
IN |
denotes |
at |
T14136 |
28740-28746 |
CD |
denotes |
15,000 |
T14137 |
28747-28750 |
NN |
denotes |
rpm |
T14138 |
28751-28754 |
IN |
denotes |
for |
T14139 |
28755-28757 |
CD |
denotes |
15 |
T14140 |
28758-28761 |
NN |
denotes |
min |
T14141 |
28762-28764 |
IN |
denotes |
at |
T14142 |
28765-28769 |
NNP |
denotes |
4°C. |
T14143 |
28770-28775 |
NNP |
denotes |
Equal |
T14144 |
28776-28783 |
NN |
denotes |
amounts |
T14145 |
28784-28786 |
IN |
denotes |
of |
T14146 |
28787-28795 |
NN |
denotes |
proteins |
T14147 |
28796-28797 |
-LRB- |
denotes |
( |
T14148 |
28797-28799 |
CD |
denotes |
40 |
T14149 |
28800-28802 |
NN |
denotes |
µg |
T14150 |
28802-28803 |
-RRB- |
denotes |
) |
T14151 |
28804-28808 |
VB |
denotes |
were |
T14152 |
28809-28818 |
VB |
denotes |
separated |
T14153 |
28819-28821 |
IN |
denotes |
on |
T14154 |
28822-28823 |
DT |
denotes |
a |
T14155 |
28824-28830 |
NN |
denotes |
SDS/12 |
T14156 |
28830-28831 |
NN |
denotes |
% |
T14157 |
28831-28846 |
NN |
denotes |
-polyacrylamide |
T14158 |
28847-28850 |
NN |
denotes |
gel |
T14159 |
28850-28851 |
-COMMA- |
denotes |
, |
T14160 |
28852-28855 |
CC |
denotes |
and |
T14161 |
28856-28860 |
RB |
denotes |
then |
T14162 |
28861-28872 |
VB |
denotes |
transferred |
T14163 |
28873-28875 |
TO |
denotes |
to |
T14164 |
28876-28877 |
DT |
denotes |
a |
T14165 |
28878-28892 |
NN |
denotes |
polyvinylidene |
T14166 |
28893-28903 |
NN |
denotes |
difluoride |
T14167 |
28904-28905 |
-LRB- |
denotes |
( |
T14168 |
28905-28909 |
NN |
denotes |
PVDF |
T14169 |
28909-28910 |
-RRB- |
denotes |
) |
T14170 |
28911-28919 |
NN |
denotes |
membrane |
T14171 |
28920-28921 |
-LRB- |
denotes |
( |
T14172 |
28921-28923 |
NNP |
denotes |
GE |
T14173 |
28924-28929 |
NNP |
denotes |
Water |
T14174 |
28930-28933 |
CC |
denotes |
and |
T14175 |
28934-28941 |
NNP |
denotes |
Process |
T14176 |
28942-28954 |
NN |
denotes |
technologies |
T14177 |
28954-28955 |
-COMMA- |
denotes |
, |
T14178 |
28956-28963 |
NNP |
denotes |
Trevose |
T14179 |
28963-28964 |
-COMMA- |
denotes |
, |
T14180 |
28965-28967 |
NNP |
denotes |
PA |
T14181 |
28967-28968 |
-COMMA- |
denotes |
, |
T14182 |
28969-28972 |
NNP |
denotes |
USA |
T14183 |
28972-28973 |
-RRB- |
denotes |
) |
T14184 |
28975-28980 |
NN |
denotes |
Blots |
T14185 |
28981-28985 |
VB |
denotes |
were |
T14186 |
28986-28993 |
VB |
denotes |
blocked |
T14187 |
28994-28997 |
IN |
denotes |
for |
T14188 |
28998-28999 |
CD |
denotes |
1 |
T14189 |
29000-29001 |
NN |
denotes |
h |
T14190 |
29002-29004 |
IN |
denotes |
at |
T14191 |
29005-29009 |
NN |
denotes |
room |
T14192 |
29010-29021 |
NN |
denotes |
temperature |
T14193 |
29022-29026 |
IN |
denotes |
with |
T14194 |
29027-29028 |
CD |
denotes |
5 |
T14195 |
29028-29029 |
NN |
denotes |
% |
T14196 |
29030-29031 |
-LRB- |
denotes |
( |
T14197 |
29031-29034 |
NN |
denotes |
w/v |
T14198 |
29034-29035 |
-RRB- |
denotes |
) |
T14199 |
29036-29043 |
JJ |
denotes |
non-fat |
T14200 |
29044-29049 |
VB |
denotes |
dried |
T14201 |
29050-29054 |
NN |
denotes |
milk |
T14202 |
29055-29057 |
IN |
denotes |
in |
T14203 |
29058-29071 |
JJ |
denotes |
Tris-Buffered |
T14204 |
29072-29078 |
NN |
denotes |
Saline |
T14205 |
29079-29087 |
CD |
denotes |
Tween-20 |
T14206 |
29088-29089 |
-LRB- |
denotes |
[ |
T14207 |
29089-29093 |
NN |
denotes |
TBST |
T14208 |
29093-29094 |
-COLON- |
denotes |
: |
T14209 |
29095-29097 |
CD |
denotes |
10 |
T14210 |
29098-29100 |
NN |
denotes |
mM |
T14211 |
29101-29105 |
NN |
denotes |
Tris |
T14212 |
29106-29107 |
-LRB- |
denotes |
( |
T14213 |
29107-29109 |
NN |
denotes |
pH |
T14214 |
29110-29113 |
CD |
denotes |
8.0 |
T14215 |
29113-29114 |
-RRB- |
denotes |
) |
T14216 |
29115-29118 |
CC |
denotes |
and |
T14217 |
29119-29122 |
CD |
denotes |
150 |
T14218 |
29123-29125 |
NN |
denotes |
mM |
T14219 |
29126-29130 |
NN |
denotes |
NaCl |
T14220 |
29131-29139 |
NN |
denotes |
solution |
T14221 |
29140-29150 |
VB |
denotes |
containing |
T14222 |
29151-29155 |
CD |
denotes |
0.05 |
T14223 |
29155-29156 |
NN |
denotes |
% |
T14224 |
29157-29165 |
CD |
denotes |
Tween-20 |
T14225 |
29165-29166 |
-RRB- |
denotes |
] |
T14226 |
29168-29173 |
IN |
denotes |
After |
T14227 |
29174-29175 |
DT |
denotes |
a |
T14228 |
29176-29181 |
JJ |
denotes |
short |
T14229 |
29182-29189 |
NN |
denotes |
washing |
T14230 |
29190-29192 |
IN |
denotes |
in |
T14231 |
29193-29197 |
NN |
denotes |
TBST |
T14232 |
29197-29198 |
-COMMA- |
denotes |
, |
T14233 |
29199-29202 |
DT |
denotes |
the |
T14234 |
29203-29212 |
NN |
denotes |
membranes |
T14235 |
29213-29217 |
VB |
denotes |
were |
T14236 |
29218-29231 |
VB |
denotes |
immunoblotted |
T14237 |
29232-29236 |
IN |
denotes |
with |
T14238 |
29237-29240 |
DT |
denotes |
the |
T14239 |
29241-29250 |
VB |
denotes |
following |
T14240 |
29251-29258 |
JJ |
denotes |
primary |
T14241 |
29259-29269 |
NN |
denotes |
antibodies |
T14242 |
29269-29270 |
-COLON- |
denotes |
: |
T14243 |
29271-29276 |
NN |
denotes |
mouse |
T14244 |
29277-29287 |
JJ |
denotes |
monoclonal |
T14245 |
29288-29298 |
NN |
denotes |
antibodies |
T14246 |
29299-29307 |
VB |
denotes |
directed |
T14247 |
29308-29315 |
IN |
denotes |
against |
T14248 |
29316-29319 |
NN |
denotes |
p65 |
T14249 |
29320-29323 |
CC |
denotes |
and |
T14250 |
29324-29327 |
NN |
denotes |
p50 |
T14251 |
29328-29329 |
-LRB- |
denotes |
( |
T14252 |
29329-29334 |
CD |
denotes |
1∶500 |
T14253 |
29335-29344 |
NN |
denotes |
dilutions |
T14254 |
29344-29345 |
-COLON- |
denotes |
; |
T14255 |
29346-29351 |
NNP |
denotes |
Santa |
T14256 |
29352-29356 |
NNP |
denotes |
Cruz |
T14257 |
29357-29370 |
NNP |
denotes |
Biotechnology |
T14258 |
29370-29371 |
-COMMA- |
denotes |
, |
T14259 |
29372-29377 |
NNP |
denotes |
Santa |
T14260 |
29378-29382 |
NNP |
denotes |
Cruz |
T14261 |
29382-29383 |
-COMMA- |
denotes |
, |
T14262 |
29384-29386 |
NNP |
denotes |
CA |
T14263 |
29386-29387 |
-RRB- |
denotes |
) |
T14264 |
29387-29388 |
-COMMA- |
denotes |
, |
T14265 |
29389-29395 |
NN |
denotes |
rabbit |
T14266 |
29396-29406 |
JJ |
denotes |
polyclonal |
T14267 |
29407-29417 |
NN |
denotes |
antibodies |
T14268 |
29418-29426 |
VB |
denotes |
directed |
T14269 |
29427-29434 |
IN |
denotes |
against |
T14270 |
29435-29438 |
NN |
denotes |
Bax |
T14271 |
29439-29442 |
CC |
denotes |
and |
T14272 |
29443-29447 |
NN |
denotes |
PARP |
T14273 |
29448-29449 |
-LRB- |
denotes |
( |
T14274 |
29449-29454 |
CD |
denotes |
1∶500 |
T14275 |
29455-29464 |
NN |
denotes |
dilutions |
T14276 |
29464-29465 |
-COLON- |
denotes |
; |
T14277 |
29466-29471 |
NNP |
denotes |
Santa |
T14278 |
29472-29476 |
NNP |
denotes |
Cruz |
T14279 |
29477-29490 |
NNP |
denotes |
Biotechnology |
T14280 |
29490-29491 |
-RRB- |
denotes |
) |
T14281 |
29491-29492 |
-COMMA- |
denotes |
, |
T14282 |
29493-29496 |
CC |
denotes |
and |
T14283 |
29497-29504 |
IN |
denotes |
against |
T14284 |
29505-29514 |
NN |
denotes |
caspase-3 |
T14285 |
29514-29515 |
-COMMA- |
denotes |
, |
T14286 |
29516-29525 |
NN |
denotes |
caspase-9 |
T14287 |
29525-29526 |
-COMMA- |
denotes |
, |
T14288 |
29527-29532 |
NN |
denotes |
Bcl-2 |
T14289 |
29533-29536 |
CC |
denotes |
and |
T14290 |
29537-29544 |
NN |
denotes |
c-IAP-1 |
T14291 |
29545-29546 |
-LRB- |
denotes |
( |
T14292 |
29546-29552 |
CD |
denotes |
1∶1000 |
T14293 |
29553-29562 |
NN |
denotes |
dilutions |
T14294 |
29562-29563 |
-COLON- |
denotes |
; |
T14295 |
29564-29568 |
NNP |
denotes |
Cell |
T14296 |
29569-29578 |
NNP |
denotes |
Signaling |
T14297 |
29579-29589 |
NNP |
denotes |
Technology |
T14298 |
29589-29590 |
-COMMA- |
denotes |
, |
T14299 |
29591-29598 |
NNP |
denotes |
Beverly |
T14300 |
29598-29599 |
-COMMA- |
denotes |
, |
T14301 |
29600-29602 |
JJ |
denotes |
MA |
T14302 |
29602-29603 |
-RRB- |
denotes |
) |
T14303 |
29605-29608 |
DT |
denotes |
The |
T14304 |
29609-29614 |
NN |
denotes |
blots |
T14305 |
29615-29619 |
VB |
denotes |
were |
T14306 |
29620-29629 |
VB |
denotes |
incubated |
T14307 |
29630-29634 |
IN |
denotes |
with |
T14308 |
29635-29638 |
DT |
denotes |
the |
T14309 |
29639-29649 |
JJ |
denotes |
respective |
T14310 |
29650-29661 |
NN |
denotes |
horseradish |
T14311 |
29662-29683 |
JJ |
denotes |
peroxidase-conjugated |
T14312 |
29684-29695 |
JJ |
denotes |
anti-rabbit |
T14313 |
29696-29698 |
CC |
denotes |
or |
T14314 |
29699-29709 |
JJ |
denotes |
anti-mouse |
T14315 |
29710-29713 |
NN |
denotes |
IgG |
T14316 |
29714-29715 |
-LRB- |
denotes |
( |
T14317 |
29715-29721 |
CD |
denotes |
1∶4000 |
T14318 |
29722-29731 |
NN |
denotes |
dilutions |
T14319 |
29731-29732 |
-COLON- |
denotes |
; |
T14320 |
29733-29738 |
NNP |
denotes |
Santa |
T14321 |
29739-29743 |
NNP |
denotes |
Cruz |
T14322 |
29744-29757 |
NNP |
denotes |
Biotechnology |
T14323 |
29757-29758 |
-RRB- |
denotes |
) |
T14324 |
29760-29774 |
JJ |
denotes |
Immunoreactive |
T14325 |
29775-29783 |
NN |
denotes |
proteins |
T14326 |
29784-29788 |
VB |
denotes |
were |
T14327 |
29789-29797 |
VB |
denotes |
detected |
T14328 |
29798-29802 |
IN |
denotes |
with |
T14329 |
29803-29806 |
DT |
denotes |
the |
T14330 |
29807-29810 |
NN |
denotes |
ECL |
T14331 |
29811-29820 |
NN |
denotes |
detection |
T14332 |
29821-29827 |
NN |
denotes |
system |
T14693 |
29830-29850 |
NN |
denotes |
Immunohistochemistry |
T14694 |
29851-29854 |
DT |
denotes |
All |
T14695 |
29855-29864 |
NN |
denotes |
specimens |
T14696 |
29865-29869 |
VB |
denotes |
were |
T14697 |
29870-29875 |
VB |
denotes |
fixed |
T14698 |
29876-29878 |
IN |
denotes |
in |
T14699 |
29879-29887 |
NN |
denotes |
formalin |
T14700 |
29888-29891 |
CC |
denotes |
and |
T14701 |
29892-29900 |
VB |
denotes |
embedded |
T14702 |
29901-29903 |
IN |
denotes |
in |
T14703 |
29904-29912 |
NN |
denotes |
paraffin |
T14704 |
29913-29916 |
IN |
denotes |
for |
T14705 |
29917-29928 |
NN |
denotes |
examination |
T14706 |
29930-29938 |
NN |
denotes |
Sections |
T14707 |
29939-29940 |
-LRB- |
denotes |
( |
T14708 |
29940-29941 |
CD |
denotes |
4 |
T14709 |
29942-29944 |
NN |
denotes |
µm |
T14710 |
29945-29950 |
JJ |
denotes |
thick |
T14711 |
29950-29951 |
-RRB- |
denotes |
) |
T14712 |
29952-29956 |
VB |
denotes |
were |
T14713 |
29957-29964 |
VB |
denotes |
stained |
T14714 |
29965-29969 |
IN |
denotes |
with |
T14715 |
29970-29971 |
NN |
denotes |
H |
T14716 |
29971-29972 |
CC |
denotes |
& |
T14717 |
29972-29973 |
NN |
denotes |
E |
T14718 |
29974-29977 |
CC |
denotes |
and |
T14719 |
29978-29986 |
VB |
denotes |
analyzed |
T14720 |
29987-29989 |
IN |
denotes |
by |
T14721 |
29990-30010 |
NN |
denotes |
immunohistochemistry |
T14722 |
30012-30015 |
DT |
denotes |
The |
T14723 |
30016-30033 |
JJ |
denotes |
paraffin-embedded |
T14724 |
30034-30042 |
NN |
denotes |
sections |
T14725 |
30043-30047 |
VB |
denotes |
were |
T14726 |
30048-30062 |
VB |
denotes |
deparaffinized |
T14727 |
30063-30066 |
CC |
denotes |
and |
T14728 |
30067-30077 |
VB |
denotes |
rehydrated |
T14729 |
30077-30078 |
-COMMA- |
denotes |
, |
T14730 |
30079-30085 |
VB |
denotes |
washed |
T14731 |
30086-30088 |
IN |
denotes |
in |
T14732 |
30089-30098 |
JJ |
denotes |
distilled |
T14733 |
30099-30104 |
NN |
denotes |
water |
T14734 |
30104-30105 |
-COMMA- |
denotes |
, |
T14735 |
30106-30109 |
CC |
denotes |
and |
T14736 |
30110-30114 |
RB |
denotes |
then |
T14737 |
30115-30124 |
VB |
denotes |
subjected |
T14738 |
30125-30127 |
TO |
denotes |
to |
T14739 |
30128-30141 |
JJ |
denotes |
heat-mediated |
T14740 |
30142-30149 |
NN |
denotes |
antigen |
T14741 |
30150-30159 |
NN |
denotes |
retrieval |
T14742 |
30161-30171 |
JJ |
denotes |
Endogenous |
T14743 |
30172-30182 |
NN |
denotes |
peroxidase |
T14744 |
30183-30191 |
NN |
denotes |
activity |
T14745 |
30192-30195 |
VB |
denotes |
was |
T14746 |
30196-30204 |
VB |
denotes |
quenched |
T14747 |
30205-30207 |
IN |
denotes |
by |
T14748 |
30208-30218 |
NN |
denotes |
incubation |
T14749 |
30219-30221 |
IN |
denotes |
in |
T14750 |
30222-30223 |
CD |
denotes |
3 |
T14751 |
30223-30224 |
NN |
denotes |
% |
T14752 |
30225-30233 |
NN |
denotes |
hydrogen |
T14753 |
30234-30242 |
NN |
denotes |
peroxide |
T14754 |
30243-30245 |
IN |
denotes |
in |
T14755 |
30246-30254 |
NN |
denotes |
methanol |
T14756 |
30255-30258 |
IN |
denotes |
for |
T14757 |
30259-30261 |
CD |
denotes |
15 |
T14758 |
30262-30265 |
NN |
denotes |
min |
T14759 |
30265-30266 |
-COMMA- |
denotes |
, |
T14760 |
30267-30275 |
VB |
denotes |
followed |
T14761 |
30276-30278 |
IN |
denotes |
by |
T14762 |
30279-30287 |
VB |
denotes |
clearing |
T14763 |
30288-30290 |
IN |
denotes |
in |
T14764 |
30291-30294 |
NNP |
denotes |
PBS |
T14765 |
30295-30298 |
IN |
denotes |
for |
T14766 |
30299-30300 |
CD |
denotes |
5 |
T14767 |
30301-30304 |
NN |
denotes |
min |
T14768 |
30306-30309 |
DT |
denotes |
The |
T14769 |
30310-30318 |
NN |
denotes |
sections |
T14770 |
30319-30323 |
VB |
denotes |
were |
T14771 |
30324-30331 |
VB |
denotes |
blocked |
T14772 |
30332-30335 |
IN |
denotes |
for |
T14773 |
30336-30338 |
CD |
denotes |
30 |
T14774 |
30339-30342 |
NN |
denotes |
min |
T14775 |
30343-30347 |
IN |
denotes |
with |
T14776 |
30348-30349 |
CD |
denotes |
3 |
T14777 |
30349-30350 |
NN |
denotes |
% |
T14778 |
30351-30357 |
JJ |
denotes |
normal |
T14779 |
30358-30363 |
NN |
denotes |
horse |
T14780 |
30364-30369 |
NN |
denotes |
serum |
T14781 |
30370-30377 |
VB |
denotes |
diluted |
T14782 |
30378-30380 |
IN |
denotes |
in |
T14783 |
30381-30384 |
NNP |
denotes |
PBS |
T14784 |
30384-30385 |
-COMMA- |
denotes |
, |
T14785 |
30386-30393 |
VB |
denotes |
blotted |
T14786 |
30393-30394 |
-COMMA- |
denotes |
, |
T14787 |
30395-30398 |
CC |
denotes |
and |
T14788 |
30399-30408 |
VB |
denotes |
incubated |
T14789 |
30409-30413 |
IN |
denotes |
with |
T14790 |
30414-30421 |
JJ |
denotes |
primary |
T14791 |
30422-30427 |
NN |
denotes |
mouse |
T14792 |
30428-30438 |
JJ |
denotes |
anti-mouse |
T14793 |
30439-30452 |
VB |
denotes |
proliferating |
T14794 |
30453-30457 |
NN |
denotes |
cell |
T14795 |
30458-30465 |
JJ |
denotes |
nuclear |
T14796 |
30466-30473 |
NN |
denotes |
antigen |
T14797 |
30474-30475 |
-LRB- |
denotes |
( |
T14798 |
30475-30479 |
NN |
denotes |
PCNA |
T14799 |
30479-30480 |
-COMMA- |
denotes |
, |
T14800 |
30481-30486 |
CD |
denotes |
1∶200 |
T14801 |
30487-30495 |
NN |
denotes |
dilution |
T14802 |
30495-30496 |
-RRB- |
denotes |
) |
T14803 |
30497-30507 |
JJ |
denotes |
monoclonal |
T14804 |
30508-30518 |
NN |
denotes |
antibodies |
T14805 |
30519-30521 |
IN |
denotes |
in |
T14806 |
30522-30530 |
VB |
denotes |
blocking |
T14807 |
30531-30536 |
NN |
denotes |
serum |
T14808 |
30537-30540 |
IN |
denotes |
for |
T14809 |
30541-30542 |
CD |
denotes |
4 |
T14810 |
30543-30544 |
NN |
denotes |
h |
T14811 |
30545-30547 |
IN |
denotes |
at |
T14812 |
30548-30552 |
NN |
denotes |
room |
T14813 |
30553-30564 |
NN |
denotes |
temperature |
T14814 |
30566-30576 |
RB |
denotes |
Thereafter |
T14815 |
30576-30577 |
-COMMA- |
denotes |
, |
T14816 |
30578-30581 |
DT |
denotes |
the |
T14817 |
30582-30588 |
NN |
denotes |
slides |
T14818 |
30589-30593 |
VB |
denotes |
were |
T14819 |
30594-30600 |
VB |
denotes |
washed |
T14820 |
30601-30606 |
CD |
denotes |
three |
T14821 |
30607-30612 |
NN |
denotes |
times |
T14822 |
30613-30616 |
IN |
denotes |
for |
T14823 |
30617-30618 |
CD |
denotes |
5 |
T14824 |
30619-30622 |
NN |
denotes |
min |
T14825 |
30623-30627 |
DT |
denotes |
each |
T14826 |
30628-30630 |
IN |
denotes |
in |
T14827 |
30631-30634 |
NNP |
denotes |
PBS |
T14828 |
30635-30638 |
CC |
denotes |
and |
T14829 |
30639-30648 |
VB |
denotes |
incubated |
T14830 |
30649-30653 |
IN |
denotes |
with |
T14831 |
30654-30666 |
VB |
denotes |
biotinylated |
T14832 |
30667-30677 |
JJ |
denotes |
anti-mouse |
T14833 |
30678-30681 |
CC |
denotes |
and |
T14834 |
30682-30693 |
JJ |
denotes |
anti-rabbit |
T14835 |
30694-30704 |
NN |
denotes |
antibodies |
T14836 |
30705-30708 |
IN |
denotes |
for |
T14837 |
30709-30710 |
CD |
denotes |
2 |
T14838 |
30711-30712 |
NN |
denotes |
h |
T14839 |
30714-30717 |
DT |
denotes |
The |
T14840 |
30718-30724 |
NN |
denotes |
slides |
T14841 |
30725-30729 |
VB |
denotes |
were |
T14842 |
30730-30736 |
VB |
denotes |
washed |
T14843 |
30737-30739 |
IN |
denotes |
in |
T14844 |
30740-30743 |
NNP |
denotes |
PBS |
T14845 |
30743-30744 |
-COMMA- |
denotes |
, |
T14846 |
30745-30753 |
VB |
denotes |
followed |
T14847 |
30754-30756 |
IN |
denotes |
by |
T14848 |
30757-30760 |
DT |
denotes |
the |
T14849 |
30761-30769 |
NN |
denotes |
addition |
T14850 |
30770-30772 |
IN |
denotes |
of |
T14851 |
30773-30776 |
DT |
denotes |
the |
T14852 |
30777-30783 |
NN |
denotes |
avidin |
T14853 |
30784-30790 |
NN |
denotes |
biotin |
T14854 |
30791-30801 |
NN |
denotes |
peroxidase |
T14855 |
30802-30809 |
NN |
denotes |
complex |
T14856 |
30810-30811 |
-LRB- |
denotes |
( |
T14857 |
30811-30814 |
NN |
denotes |
ABC |
T14858 |
30815-30818 |
NN |
denotes |
kit |
T14859 |
30818-30819 |
-COLON- |
denotes |
; |
T14860 |
30820-30826 |
NNP |
denotes |
Vector |
T14861 |
30827-30839 |
NNP |
denotes |
Laboratories |
T14862 |
30839-30840 |
-COMMA- |
denotes |
, |
T14863 |
30841-30851 |
NNP |
denotes |
Burlingame |
T14864 |
30851-30852 |
-COMMA- |
denotes |
, |
T14865 |
30853-30855 |
NNP |
denotes |
CA |
T14866 |
30855-30856 |
-COMMA- |
denotes |
, |
T14867 |
30857-30860 |
NNP |
denotes |
USA |
T14868 |
30860-30861 |
-RRB- |
denotes |
) |
T14869 |
30863-30866 |
DT |
denotes |
The |
T14870 |
30867-30873 |
NN |
denotes |
slides |
T14871 |
30874-30878 |
VB |
denotes |
were |
T14872 |
30879-30885 |
VB |
denotes |
washed |
T14873 |
30886-30889 |
CC |
denotes |
and |
T14874 |
30890-30893 |
DT |
denotes |
the |
T14875 |
30894-30904 |
NN |
denotes |
peroxidase |
T14876 |
30905-30913 |
NN |
denotes |
reaction |
T14877 |
30914-30917 |
VB |
denotes |
was |
T14878 |
30918-30927 |
VB |
denotes |
developed |
T14879 |
30928-30932 |
IN |
denotes |
with |
T14880 |
30933-30949 |
NN |
denotes |
diaminobenzidine |
T14881 |
30950-30951 |
-LRB- |
denotes |
( |
T14882 |
30951-30954 |
NN |
denotes |
DAB |
T14883 |
30954-30955 |
-RRB- |
denotes |
) |
T14884 |
30956-30959 |
CC |
denotes |
and |
T14885 |
30960-30968 |
NN |
denotes |
peroxide |
T14886 |
30968-30969 |
-COMMA- |
denotes |
, |
T14887 |
30970-30978 |
VB |
denotes |
followed |
T14888 |
30979-30981 |
IN |
denotes |
by |
T14889 |
30982-30997 |
VB |
denotes |
counterstaining |
T14890 |
30998-31002 |
IN |
denotes |
with |
T14891 |
31003-31014 |
NN |
denotes |
hematoxylin |
T14892 |
31014-31015 |
-COMMA- |
denotes |
, |
T14893 |
31016-31024 |
VB |
denotes |
mounting |
T14894 |
31025-31027 |
IN |
denotes |
in |
T14895 |
31028-31038 |
JJ |
denotes |
aqua-mount |
T14896 |
31038-31039 |
-COMMA- |
denotes |
, |
T14897 |
31040-31043 |
CC |
denotes |
and |
T14898 |
31044-31054 |
NN |
denotes |
evaluation |
T14899 |
31055-31060 |
IN |
denotes |
under |
T14900 |
31061-31062 |
DT |
denotes |
a |
T14901 |
31063-31068 |
JJ |
denotes |
light |
T14902 |
31069-31079 |
NN |
denotes |
microscope |
T14903 |
31080-31081 |
-LRB- |
denotes |
( |
T14904 |
31081-31098 |
NN |
denotes |
magnification×200 |
T14905 |
31098-31099 |
-COLON- |
denotes |
; |
T14906 |
31100-31107 |
NNP |
denotes |
Olympus |
T14907 |
31107-31108 |
-COMMA- |
denotes |
, |
T14908 |
31109-31114 |
NNP |
denotes |
Tokyo |
T14909 |
31114-31115 |
-COMMA- |
denotes |
, |
T14910 |
31116-31121 |
NNP |
denotes |
Japan |
T14911 |
31121-31122 |
-RRB- |
denotes |
) |
T14912 |
31124-31125 |
DT |
denotes |
A |
T14913 |
31126-31134 |
JJ |
denotes |
negative |
T14914 |
31135-31142 |
NN |
denotes |
control |
T14915 |
31143-31146 |
VB |
denotes |
was |
T14916 |
31147-31155 |
VB |
denotes |
included |
T14917 |
31156-31158 |
IN |
denotes |
in |
T14918 |
31159-31162 |
DT |
denotes |
all |
T14919 |
31163-31174 |
NN |
denotes |
experiments |
T14920 |
31175-31177 |
IN |
denotes |
by |
T14921 |
31178-31186 |
VB |
denotes |
omitting |
T14922 |
31187-31190 |
DT |
denotes |
the |
T14923 |
31191-31198 |
JJ |
denotes |
primary |
T14924 |
31199-31207 |
NN |
denotes |
antibody |
T14925 |
31209-31212 |
IN |
denotes |
For |
T14926 |
31213-31216 |
DT |
denotes |
the |
T14927 |
31217-31226 |
NN |
denotes |
detection |
T14928 |
31227-31229 |
IN |
denotes |
of |
T14929 |
31230-31239 |
JJ |
denotes |
apoptotic |
T14930 |
31240-31244 |
NN |
denotes |
cell |
T14931 |
31245-31250 |
NN |
denotes |
death |
T14932 |
31251-31253 |
IN |
denotes |
in |
T14933 |
31254-31257 |
DT |
denotes |
the |
T14934 |
31258-31263 |
NN |
denotes |
tumor |
T14935 |
31264-31271 |
NN |
denotes |
tissues |
T14936 |
31271-31272 |
-COMMA- |
denotes |
, |
T14937 |
31273-31276 |
DT |
denotes |
the |
T14938 |
31277-31294 |
JJ |
denotes |
paraffin-embedded |
T14939 |
31295-31303 |
NN |
denotes |
sections |
T14940 |
31304-31308 |
VB |
denotes |
were |
T14941 |
31309-31318 |
VB |
denotes |
incubated |
T14942 |
31319-31321 |
IN |
denotes |
in |
T14943 |
31322-31323 |
DT |
denotes |
a |
T14944 |
31324-31331 |
NN |
denotes |
mixture |
T14945 |
31332-31334 |
IN |
denotes |
of |
T14946 |
31335-31338 |
DT |
denotes |
the |
T14947 |
31339-31347 |
NN |
denotes |
labeling |
T14948 |
31348-31356 |
NN |
denotes |
solution |
T14949 |
31357-31358 |
-LRB- |
denotes |
( |
T14950 |
31358-31361 |
CD |
denotes |
540 |
T14951 |
31362-31364 |
NN |
denotes |
µl |
T14952 |
31364-31365 |
-RRB- |
denotes |
) |
T14953 |
31366-31369 |
CC |
denotes |
and |
T14954 |
31370-31376 |
NN |
denotes |
enzyme |
T14955 |
31377-31385 |
NN |
denotes |
solution |
T14956 |
31386-31387 |
-LRB- |
denotes |
( |
T14957 |
31387-31389 |
CD |
denotes |
60 |
T14958 |
31390-31392 |
NN |
denotes |
µl |
T14959 |
31392-31393 |
-RRB- |
denotes |
) |
T14960 |
31394-31397 |
IN |
denotes |
for |
T14961 |
31398-31399 |
CD |
denotes |
1 |
T14962 |
31400-31401 |
NN |
denotes |
h |
T14963 |
31402-31404 |
IN |
denotes |
at |
T14964 |
31405-31409 |
NN |
denotes |
37°C |
T14965 |
31409-31410 |
-COMMA- |
denotes |
, |
T14966 |
31411-31414 |
CC |
denotes |
and |
T14967 |
31415-31419 |
RB |
denotes |
then |
T14968 |
31420-31426 |
VB |
denotes |
washed |
T14969 |
31427-31432 |
CD |
denotes |
three |
T14970 |
31433-31438 |
NN |
denotes |
times |
T14971 |
31439-31441 |
IN |
denotes |
in |
T14972 |
31442-31445 |
CD |
denotes |
0.1 |
T14973 |
31446-31447 |
NN |
denotes |
M |
T14974 |
31448-31451 |
NNP |
denotes |
PBS |
T14975 |
31452-31455 |
IN |
denotes |
for |
T14976 |
31456-31457 |
CD |
denotes |
5 |
T14977 |
31458-31461 |
NN |
denotes |
min |
T14978 |
31462-31466 |
DT |
denotes |
each |
T14979 |
31466-31467 |
-COMMA- |
denotes |
, |
T14980 |
31468-31477 |
VB |
denotes |
according |
T14981 |
31478-31480 |
TO |
denotes |
to |
T14982 |
31481-31484 |
DT |
denotes |
the |
T14983 |
31485-31499 |
NN |
denotes |
manufacturer’s |
T14984 |
31500-31512 |
NN |
denotes |
instructions |
T14985 |
31514-31518 |
RB |
denotes |
Next |
T14986 |
31518-31519 |
-COMMA- |
denotes |
, |
T14987 |
31520-31523 |
DT |
denotes |
the |
T14988 |
31524-31532 |
NN |
denotes |
sections |
T14989 |
31533-31537 |
VB |
denotes |
were |
T14990 |
31538-31547 |
VB |
denotes |
incubated |
T14991 |
31548-31552 |
IN |
denotes |
with |
T14992 |
31553-31555 |
NN |
denotes |
4′ |
T14993 |
31555-31556 |
-COMMA- |
denotes |
, |
T14994 |
31556-31582 |
NN |
denotes |
6-diamidino-2-phenylindole |
T14995 |
31583-31584 |
-LRB- |
denotes |
( |
T14996 |
31584-31588 |
NN |
denotes |
DAPI |
T14997 |
31588-31589 |
-RRB- |
denotes |
) |
T14998 |
31590-31593 |
IN |
denotes |
for |
T14999 |
31594-31596 |
CD |
denotes |
15 |
T15000 |
31597-31600 |
NN |
denotes |
min |
T15001 |
31601-31603 |
IN |
denotes |
at |
T15002 |
31604-31609 |
NNP |
denotes |
37°C. |
T15003 |
31610-31617 |
NNP |
denotes |
Finally |
T15004 |
31617-31618 |
-COMMA- |
denotes |
, |
T15005 |
31619-31622 |
DT |
denotes |
the |
T15006 |
31623-31631 |
NN |
denotes |
sections |
T15007 |
31632-31636 |
VB |
denotes |
were |
T15008 |
31637-31643 |
VB |
denotes |
rinsed |
T15009 |
31643-31644 |
-COMMA- |
denotes |
, |
T15010 |
31645-31652 |
VB |
denotes |
mounted |
T15011 |
31653-31655 |
IN |
denotes |
on |
T15012 |
31656-31662 |
NN |
denotes |
slides |
T15013 |
31662-31663 |
-COMMA- |
denotes |
, |
T15014 |
31664-31667 |
CC |
denotes |
and |
T15015 |
31668-31681 |
JJ |
denotes |
cover-slipped |
T15016 |
31682-31685 |
IN |
denotes |
for |
T15017 |
31686-31698 |
NN |
denotes |
fluorescence |
T15018 |
31699-31709 |
NN |
denotes |
microscopy |
T15019 |
31710-31711 |
-LRB- |
denotes |
( |
T15020 |
31711-31714 |
NN |
denotes |
DAS |
T15021 |
31715-31725 |
NN |
denotes |
microscope |
T15022 |
31725-31726 |
-RRB- |
denotes |
) |
T15449 |
31729-31747 |
NN |
denotes |
Immunofluorescence |
T15450 |
32314-32321 |
RB |
denotes |
Finally |
T15451 |
32321-32322 |
-COMMA- |
denotes |
, |
T15452 |
32323-32326 |
DT |
denotes |
the |
T15453 |
32327-32335 |
NN |
denotes |
sections |
T15454 |
32336-32340 |
VB |
denotes |
were |
T15455 |
32341-32347 |
VB |
denotes |
rinsed |
T15456 |
32347-32348 |
-COMMA- |
denotes |
, |
T15457 |
32349-32356 |
VB |
denotes |
mounted |
T15458 |
32357-32359 |
IN |
denotes |
on |
T15459 |
32360-32366 |
NN |
denotes |
slides |
T15460 |
32366-32367 |
-COMMA- |
denotes |
, |
T15461 |
32368-32371 |
CC |
denotes |
and |
T15462 |
32372-32385 |
JJ |
denotes |
cover-slipped |
T15463 |
32386-32389 |
IN |
denotes |
for |
T15464 |
32390-32402 |
NN |
denotes |
fluorescence |
T15465 |
32403-32413 |
NN |
denotes |
microscopy |
T15466 |
32414-32417 |
CC |
denotes |
and |
T15467 |
32418-32429 |
NN |
denotes |
photography |
T15468 |
32430-32435 |
VB |
denotes |
using |
T15469 |
32436-32443 |
NN |
denotes |
ApoTome |
T15470 |
32444-32454 |
NN |
denotes |
microscopy |
T15471 |
32455-32456 |
-LRB- |
denotes |
( |
T15472 |
32456-32460 |
NNP |
denotes |
Carl |
T15473 |
32461-32466 |
NNP |
denotes |
Zeiss |
T15474 |
32466-32467 |
-COMMA- |
denotes |
, |
T15475 |
32468-32477 |
NNP |
denotes |
Thornwood |
T15476 |
32477-32478 |
-COMMA- |
denotes |
, |
T15477 |
32479-32481 |
NNP |
denotes |
NY |
T15478 |
32481-32482 |
-COMMA- |
denotes |
, |
T15479 |
32483-32486 |
NNP |
denotes |
USA |
T15480 |
32486-32487 |
-RRB- |
denotes |
) |
T15697 |
32490-32493 |
NN |
denotes |
Gel |
T15698 |
32494-32509 |
NN |
denotes |
Electromobility |
T15699 |
32510-32515 |
NN |
denotes |
Shift |
T15700 |
32516-32521 |
NN |
denotes |
Assay |
T15701 |
32522-32523 |
DT |
denotes |
A |
T15702 |
32524-32527 |
NN |
denotes |
gel |
T15703 |
32528-32543 |
NN |
denotes |
electromobility |
T15704 |
32544-32549 |
NN |
denotes |
shift |
T15705 |
32550-32555 |
NN |
denotes |
assay |
T15706 |
32556-32557 |
-LRB- |
denotes |
( |
T15707 |
32557-32561 |
NN |
denotes |
EMSA |
T15708 |
32561-32562 |
-RRB- |
denotes |
) |
T15709 |
32563-32566 |
VB |
denotes |
was |
T15710 |
32567-32576 |
VB |
denotes |
performed |
T15711 |
32577-32586 |
VB |
denotes |
according |
T15712 |
32587-32589 |
TO |
denotes |
to |
T15713 |
32590-32593 |
DT |
denotes |
the |
T15714 |
32594-32608 |
NN |
denotes |
manufacturer’s |
T15715 |
32609-32624 |
NN |
denotes |
recommendations |
T15716 |
32625-32626 |
-LRB- |
denotes |
( |
T15717 |
32626-32633 |
NNP |
denotes |
Promega |
T15718 |
32633-32634 |
-COMMA- |
denotes |
, |
T15719 |
32635-32642 |
NNP |
denotes |
Madison |
T15720 |
32642-32643 |
-COMMA- |
denotes |
, |
T15721 |
32644-32646 |
NNP |
denotes |
WI |
T15722 |
32646-32647 |
-RRB- |
denotes |
) |
T15723 |
32649-32652 |
DT |
denotes |
The |
T15724 |
32653-32658 |
NN |
denotes |
tumor |
T15725 |
32659-32666 |
NN |
denotes |
tissues |
T15726 |
32667-32671 |
VB |
denotes |
were |
T15727 |
32672-32679 |
RB |
denotes |
briefly |
T15728 |
32680-32691 |
VB |
denotes |
homogenized |
T15729 |
32692-32694 |
IN |
denotes |
in |
T15730 |
32695-32698 |
CD |
denotes |
200 |
T15731 |
32699-32701 |
NN |
denotes |
µl |
T15732 |
32702-32704 |
IN |
denotes |
of |
T15733 |
32705-32713 |
NN |
denotes |
solution |
T15734 |
32714-32715 |
NN |
denotes |
A |
T15735 |
32716-32717 |
-LRB- |
denotes |
( |
T15736 |
32717-32719 |
CD |
denotes |
10 |
T15737 |
32720-32722 |
NN |
denotes |
mM |
T15738 |
32723-32728 |
NN |
denotes |
HEPES |
T15739 |
32729-32730 |
-LRB- |
denotes |
[ |
T15740 |
32730-32732 |
NN |
denotes |
pH |
T15741 |
32733-32736 |
CD |
denotes |
7.9 |
T15742 |
32736-32737 |
-RRB- |
denotes |
] |
T15743 |
32737-32738 |
-COMMA- |
denotes |
, |
T15744 |
32739-32742 |
CD |
denotes |
1.5 |
T15745 |
32743-32745 |
NN |
denotes |
mM |
T15746 |
32746-32751 |
NN |
denotes |
MgCl2 |
T15747 |
32751-32752 |
-COMMA- |
denotes |
, |
T15748 |
32753-32755 |
CD |
denotes |
10 |
T15749 |
32756-32758 |
NN |
denotes |
mM |
T15750 |
32759-32762 |
NN |
denotes |
KCl |
T15751 |
32762-32763 |
-COMMA- |
denotes |
, |
T15752 |
32764-32767 |
CD |
denotes |
0.5 |
T15753 |
32768-32770 |
NN |
denotes |
mM |
T15754 |
32771-32785 |
NN |
denotes |
dithiothreitol |
T15755 |
32785-32786 |
-COMMA- |
denotes |
, |
T15756 |
32787-32790 |
CD |
denotes |
0.2 |
T15757 |
32791-32793 |
NN |
denotes |
mM |
T15758 |
32794-32822 |
NN |
denotes |
phenylmethylsulfonylfluoride |
T15759 |
32822-32823 |
-RRB- |
denotes |
) |
T15760 |
32823-32824 |
-COMMA- |
denotes |
, |
T15761 |
32825-32833 |
VB |
denotes |
vortexed |
T15762 |
32834-32844 |
RB |
denotes |
vigorously |
T15763 |
32844-32845 |
-COMMA- |
denotes |
, |
T15764 |
32846-32855 |
VB |
denotes |
incubated |
T15765 |
32856-32858 |
IN |
denotes |
on |
T15766 |
32859-32862 |
NN |
denotes |
ice |
T15767 |
32863-32866 |
IN |
denotes |
for |
T15768 |
32867-32869 |
CD |
denotes |
10 |
T15769 |
32870-32873 |
NN |
denotes |
min |
T15770 |
32873-32874 |
-COMMA- |
denotes |
, |
T15771 |
32875-32878 |
CC |
denotes |
and |
T15772 |
32879-32883 |
RB |
denotes |
then |
T15773 |
32884-32895 |
VB |
denotes |
centrifuged |
T15774 |
32896-32898 |
IN |
denotes |
at |
T15775 |
32899-32904 |
CD |
denotes |
15000 |
T15776 |
32905-32908 |
NN |
denotes |
rpm |
T15777 |
32909-32912 |
IN |
denotes |
for |
T15778 |
32913-32915 |
CD |
denotes |
15 |
T15779 |
32916-32919 |
NN |
denotes |
min |
T15780 |
32921-32924 |
DT |
denotes |
The |
T15781 |
32925-32933 |
VB |
denotes |
pelleted |
T15782 |
32934-32940 |
NN |
denotes |
nuclei |
T15783 |
32941-32945 |
VB |
denotes |
were |
T15784 |
32946-32957 |
VB |
denotes |
resuspended |
T15785 |
32958-32960 |
IN |
denotes |
in |
T15786 |
32961-32969 |
NN |
denotes |
solution |
T15787 |
32970-32971 |
NN |
denotes |
C |
T15788 |
32972-32973 |
-LRB- |
denotes |
( |
T15789 |
32973-32981 |
NN |
denotes |
solution |
T15790 |
32982-32983 |
NN |
denotes |
A |
T15791 |
32984-32996 |
VB |
denotes |
supplemented |
T15792 |
32997-33001 |
IN |
denotes |
with |
T15793 |
33002-33005 |
CD |
denotes |
420 |
T15794 |
33006-33008 |
NN |
denotes |
mM |
T15795 |
33009-33013 |
NN |
denotes |
NaCl |
T15796 |
33014-33017 |
CC |
denotes |
and |
T15797 |
33018-33020 |
CD |
denotes |
20 |
T15798 |
33020-33021 |
NN |
denotes |
% |
T15799 |
33022-33030 |
NN |
denotes |
glycerol |
T15800 |
33030-33031 |
-RRB- |
denotes |
) |
T15801 |
33031-33032 |
-COMMA- |
denotes |
, |
T15802 |
33033-33036 |
CC |
denotes |
and |
T15803 |
33037-33046 |
VB |
denotes |
incubated |
T15804 |
33047-33049 |
IN |
denotes |
on |
T15805 |
33050-33053 |
NN |
denotes |
ice |
T15806 |
33054-33057 |
IN |
denotes |
for |
T15807 |
33058-33060 |
CD |
denotes |
20 |
T15808 |
33061-33064 |
NN |
denotes |
min |
T15809 |
33066-33069 |
DT |
denotes |
The |
T15810 |
33070-33081 |
JJ |
denotes |
resuspended |
T15811 |
33082-33088 |
NN |
denotes |
pellet |
T15812 |
33089-33092 |
VB |
denotes |
was |
T15813 |
33093-33104 |
VB |
denotes |
centrifuged |
T15814 |
33105-33107 |
IN |
denotes |
at |
T15815 |
33108-33113 |
CD |
denotes |
15000 |
T15816 |
33114-33117 |
NN |
denotes |
rpm |
T15817 |
33118-33121 |
IN |
denotes |
for |
T15818 |
33122-33124 |
CD |
denotes |
15 |
T15819 |
33125-33128 |
NN |
denotes |
min |
T15820 |
33128-33129 |
-COMMA- |
denotes |
, |
T15821 |
33130-33133 |
CC |
denotes |
and |
T15822 |
33134-33137 |
DT |
denotes |
the |
T15823 |
33138-33147 |
VB |
denotes |
resulting |
T15824 |
33148-33155 |
JJ |
denotes |
nuclear |
T15825 |
33156-33164 |
NN |
denotes |
extracts |
T15826 |
33165-33176 |
NN |
denotes |
supernatant |
T15827 |
33177-33181 |
VB |
denotes |
were |
T15828 |
33182-33191 |
VB |
denotes |
collected |
T15829 |
33192-33194 |
IN |
denotes |
in |
T15830 |
33195-33196 |
DT |
denotes |
a |
T15831 |
33197-33204 |
JJ |
denotes |
chilled |
T15832 |
33205-33214 |
NNP |
denotes |
Eppendorf |
T15833 |
33215-33219 |
NN |
denotes |
tube |
T15834 |
33221-33230 |
NNP |
denotes |
Consensus |
T15835 |
33231-33247 |
NN |
denotes |
oligonucleotides |
T15836 |
33248-33252 |
VB |
denotes |
were |
T15837 |
33253-33264 |
VB |
denotes |
end-labeled |
T15838 |
33265-33270 |
VB |
denotes |
using |
T15839 |
33271-33273 |
NN |
denotes |
T4 |
T15840 |
33274-33288 |
NN |
denotes |
polynucleotide |
T15841 |
33289-33295 |
NN |
denotes |
kinase |
T15842 |
33296-33299 |
CC |
denotes |
and |
T15843 |
33300-33301 |
-LRB- |
denotes |
[ |
T15844 |
33301-33304 |
NN |
denotes |
P32 |
T15845 |
33304-33305 |
-RRB- |
denotes |
] |
T15846 |
33305-33309 |
NN |
denotes |
-ATP |
T15847 |
33310-33313 |
IN |
denotes |
for |
T15848 |
33314-33316 |
CD |
denotes |
10 |
T15849 |
33317-33320 |
NN |
denotes |
min |
T15850 |
33321-33323 |
IN |
denotes |
at |
T15851 |
33324-33329 |
NNP |
denotes |
37°C. |
T15852 |
33330-33333 |
DT |
denotes |
The |
T15853 |
33334-33337 |
NN |
denotes |
gel |
T15854 |
33338-33343 |
NN |
denotes |
shift |
T15855 |
33344-33353 |
NN |
denotes |
reactions |
T15856 |
33354-33358 |
VB |
denotes |
were |
T15857 |
33359-33368 |
VB |
denotes |
assembled |
T15858 |
33369-33372 |
CC |
denotes |
and |
T15859 |
33373-33382 |
VB |
denotes |
incubated |
T15860 |
33383-33385 |
IN |
denotes |
at |
T15861 |
33386-33390 |
NN |
denotes |
room |
T15862 |
33391-33402 |
NN |
denotes |
temperature |
T15863 |
33404-33416 |
RB |
denotes |
Subsequently |
T15864 |
33416-33417 |
-COMMA- |
denotes |
, |
T15865 |
33418-33419 |
CD |
denotes |
1 |
T15866 |
33420-33422 |
NN |
denotes |
ml |
T15867 |
33423-33425 |
IN |
denotes |
of |
T15868 |
33426-33429 |
NN |
denotes |
gel |
T15869 |
33430-33437 |
NN |
denotes |
loading |
T15870 |
33438-33444 |
NN |
denotes |
buffer |
T15871 |
33445-33448 |
VB |
denotes |
was |
T15872 |
33449-33454 |
VB |
denotes |
added |
T15873 |
33455-33457 |
TO |
denotes |
to |
T15874 |
33458-33462 |
DT |
denotes |
each |
T15875 |
33463-33471 |
NN |
denotes |
reaction |
T15876 |
33472-33475 |
CC |
denotes |
and |
T15877 |
33476-33482 |
VB |
denotes |
loaded |
T15878 |
33483-33487 |
IN |
denotes |
onto |
T15879 |
33488-33489 |
DT |
denotes |
a |
T15880 |
33490-33491 |
CD |
denotes |
6 |
T15881 |
33491-33492 |
NN |
denotes |
% |
T15882 |
33493-33509 |
JJ |
denotes |
non-denaturating |
T15883 |
33510-33513 |
NN |
denotes |
gel |
T15884 |
33515-33518 |
DT |
denotes |
The |
T15885 |
33519-33522 |
NN |
denotes |
gel |
T15886 |
33523-33526 |
VB |
denotes |
was |
T15887 |
33527-33536 |
VB |
denotes |
subjected |
T15888 |
33537-33539 |
TO |
denotes |
to |
T15889 |
33540-33555 |
NN |
denotes |
electrophoresis |
T15890 |
33556-33561 |
IN |
denotes |
until |
T15891 |
33562-33565 |
DT |
denotes |
the |
T15892 |
33566-33569 |
NN |
denotes |
dye |
T15893 |
33570-33573 |
VB |
denotes |
was |
T15894 |
33574-33585 |
NN |
denotes |
four-fifths |
T15895 |
33586-33588 |
IN |
denotes |
of |
T15896 |
33589-33592 |
DT |
denotes |
the |
T15897 |
33593-33596 |
NN |
denotes |
way |
T15898 |
33597-33601 |
IN |
denotes |
down |
T15899 |
33602-33605 |
DT |
denotes |
the |
T15900 |
33606-33609 |
NN |
denotes |
gel |
T15901 |
33611-33614 |
DT |
denotes |
The |
T15902 |
33615-33618 |
NN |
denotes |
gel |
T15903 |
33619-33622 |
VB |
denotes |
was |
T15904 |
33623-33628 |
VB |
denotes |
dried |
T15905 |
33629-33632 |
IN |
denotes |
for |
T15906 |
33633-33634 |
CD |
denotes |
1 |
T15907 |
33635-33636 |
NN |
denotes |
h |
T15908 |
33637-33639 |
IN |
denotes |
at |
T15909 |
33640-33644 |
NN |
denotes |
80°C |
T15910 |
33645-33648 |
CC |
denotes |
and |
T15911 |
33649-33656 |
VB |
denotes |
exposed |
T15912 |
33657-33659 |
TO |
denotes |
to |
T15913 |
33660-33664 |
VB |
denotes |
film |
T15914 |
33665-33674 |
NN |
denotes |
overnight |
T15915 |
33675-33677 |
IN |
denotes |
at |
T15916 |
33678-33683 |
NN |
denotes |
-70°C |
T16223 |
33686-33690 |
NN |
denotes |
Flow |
T16224 |
33691-33701 |
JJ |
denotes |
Cytometric |
T16225 |
33702-33710 |
NN |
denotes |
Analysis |
T16226 |
33711-33722 |
NN |
denotes |
Lymphocytes |
T16227 |
33723-33727 |
VB |
denotes |
were |
T16228 |
33728-33736 |
VB |
denotes |
obtained |
T16229 |
33737-33741 |
IN |
denotes |
from |
T16230 |
33742-33747 |
NN |
denotes |
tumor |
T16231 |
33748-33751 |
CC |
denotes |
and |
T16232 |
33752-33758 |
NN |
denotes |
spleen |
T16233 |
33759-33766 |
NN |
denotes |
tissues |
T16234 |
33767-33770 |
IN |
denotes |
for |
T16235 |
33771-33780 |
NN |
denotes |
phenotype |
T16236 |
33781-33789 |
NN |
denotes |
analysis |
T16237 |
33791-33797 |
NN |
denotes |
Spleen |
T16238 |
33798-33801 |
CC |
denotes |
and |
T16239 |
33802-33807 |
NN |
denotes |
tumor |
T16240 |
33808-33819 |
NN |
denotes |
lymphocytes |
T16241 |
33820-33824 |
VB |
denotes |
were |
T16242 |
33825-33833 |
VB |
denotes |
isolated |
T16243 |
33834-33838 |
IN |
denotes |
from |
T16244 |
33839-33844 |
JJ |
denotes |
fresh |
T16245 |
33845-33851 |
NN |
denotes |
spleen |
T16246 |
33852-33855 |
CC |
denotes |
and |
T16247 |
33856-33861 |
NN |
denotes |
tumor |
T16248 |
33862-33870 |
NN |
denotes |
biopsies |
T16249 |
33871-33879 |
VB |
denotes |
obtained |
T16250 |
33880-33884 |
IN |
denotes |
from |
T16251 |
33885-33890 |
CD |
denotes |
three |
T16252 |
33891-33895 |
NN |
denotes |
mice |
T16253 |
33896-33899 |
IN |
denotes |
per |
T16254 |
33900-33905 |
NN |
denotes |
group |
T16255 |
33907-33913 |
NN |
denotes |
Spleen |
T16256 |
33914-33917 |
CC |
denotes |
and |
T16257 |
33918-33923 |
NN |
denotes |
tumor |
T16258 |
33924-33932 |
NN |
denotes |
biopsies |
T16259 |
33933-33937 |
VB |
denotes |
were |
T16260 |
33938-33945 |
RB |
denotes |
briefly |
T16261 |
33946-33957 |
VB |
denotes |
homogenized |
T16262 |
33958-33970 |
RB |
denotes |
mechanically |
T16263 |
33971-33973 |
IN |
denotes |
in |
T16264 |
33974-33977 |
NNP |
denotes |
PBS |
T16265 |
33977-33978 |
-COMMA- |
denotes |
, |
T16266 |
33979-33987 |
VB |
denotes |
filtered |
T16267 |
33988-33989 |
-LRB- |
denotes |
( |
T16268 |
33989-33992 |
CD |
denotes |
100 |
T16269 |
33993-33995 |
NN |
denotes |
µm |
T16270 |
33996-34000 |
NN |
denotes |
cell |
T16271 |
34001-34009 |
NN |
denotes |
strainer |
T16272 |
34009-34010 |
-COLON- |
denotes |
; |
T16273 |
34011-34013 |
NN |
denotes |
BD |
T16274 |
34014-34024 |
NN |
denotes |
PharMingen |
T16275 |
34024-34025 |
-RRB- |
denotes |
) |
T16276 |
34026-34029 |
CC |
denotes |
and |
T16277 |
34030-34034 |
RB |
denotes |
then |
T16278 |
34035-34041 |
VB |
denotes |
placed |
T16279 |
34042-34044 |
IN |
denotes |
in |
T16280 |
34045-34050 |
NN |
denotes |
lysis |
T16281 |
34051-34057 |
NN |
denotes |
buffer |
T16282 |
34058-34059 |
-LRB- |
denotes |
( |
T16283 |
34059-34062 |
NN |
denotes |
ACK |
T16284 |
34063-34069 |
NN |
denotes |
lysing |
T16285 |
34070-34076 |
NN |
denotes |
buffer |
T16286 |
34076-34077 |
-COMMA- |
denotes |
, |
T16287 |
34078-34083 |
NN |
denotes |
LONZA |
T16288 |
34083-34084 |
-RRB- |
denotes |
) |
T16289 |
34085-34087 |
TO |
denotes |
to |
T16290 |
34088-34094 |
VB |
denotes |
remove |
T16291 |
34095-34098 |
JJ |
denotes |
red |
T16292 |
34099-34104 |
NN |
denotes |
blood |
T16293 |
34105-34110 |
NN |
denotes |
cells |
T16294 |
34112-34115 |
CD |
denotes |
One |
T16295 |
34116-34123 |
CD |
denotes |
million |
T16296 |
34124-34135 |
NN |
denotes |
splenocytes |
T16297 |
34136-34140 |
VB |
denotes |
were |
T16298 |
34141-34147 |
VB |
denotes |
washed |
T16299 |
34148-34152 |
RB |
denotes |
once |
T16300 |
34153-34155 |
IN |
denotes |
in |
T16301 |
34156-34159 |
NN |
denotes |
PBS |
T16302 |
34160-34170 |
VB |
denotes |
containing |
T16303 |
34171-34172 |
CD |
denotes |
1 |
T16304 |
34172-34173 |
NN |
denotes |
% |
T16305 |
34174-34180 |
JJ |
denotes |
bovine |
T16306 |
34181-34186 |
NN |
denotes |
serum |
T16307 |
34187-34194 |
NN |
denotes |
albumin |
T16308 |
34195-34196 |
-LRB- |
denotes |
( |
T16309 |
34196-34199 |
NN |
denotes |
BSA |
T16310 |
34199-34200 |
-RRB- |
denotes |
) |
T16311 |
34201-34204 |
CC |
denotes |
and |
T16312 |
34205-34217 |
JJ |
denotes |
re-suspended |
T16313 |
34218-34220 |
IN |
denotes |
in |
T16314 |
34221-34224 |
CD |
denotes |
100 |
T16315 |
34225-34227 |
NN |
denotes |
µl |
T16316 |
34228-34230 |
IN |
denotes |
of |
T16317 |
34231-34238 |
NN |
denotes |
PBS/BSA |
T16318 |
34239-34245 |
NN |
denotes |
buffer |
T16319 |
34247-34256 |
RB |
denotes |
Meanwhile |
T16320 |
34256-34257 |
-COMMA- |
denotes |
, |
T16321 |
34258-34261 |
CD |
denotes |
one |
T16322 |
34262-34269 |
CD |
denotes |
million |
T16323 |
34270-34275 |
NN |
denotes |
cells |
T16324 |
34276-34284 |
VB |
denotes |
obtained |
T16325 |
34285-34289 |
IN |
denotes |
from |
T16326 |
34290-34295 |
NN |
denotes |
tumor |
T16327 |
34296-34303 |
NN |
denotes |
tissues |
T16328 |
34304-34308 |
VB |
denotes |
were |
T16329 |
34309-34315 |
VB |
denotes |
placed |
T16330 |
34316-34318 |
IN |
denotes |
in |
T16331 |
34319-34323 |
NN |
denotes |
RPMI |
T16332 |
34324-34330 |
NN |
denotes |
medium |
T16333 |
34330-34331 |
-COMMA- |
denotes |
, |
T16334 |
34332-34341 |
VB |
denotes |
incubated |
T16335 |
34342-34344 |
TO |
denotes |
to |
T16336 |
34345-34351 |
VB |
denotes |
obtain |
T16337 |
34352-34362 |
NN |
denotes |
suspension |
T16338 |
34363-34367 |
NN |
denotes |
cell |
T16339 |
34368-34371 |
IN |
denotes |
for |
T16340 |
34372-34377 |
NN |
denotes |
1hour |
T16341 |
34378-34380 |
IN |
denotes |
at |
T16342 |
34381-34385 |
NN |
denotes |
37°C |
T16343 |
34385-34386 |
-COMMA- |
denotes |
, |
T16344 |
34387-34398 |
VB |
denotes |
centrifuged |
T16345 |
34399-34400 |
-LRB- |
denotes |
( |
T16346 |
34400-34404 |
CD |
denotes |
1200 |
T16347 |
34405-34408 |
NN |
denotes |
rpm |
T16348 |
34408-34409 |
-COMMA- |
denotes |
, |
T16349 |
34410-34411 |
CD |
denotes |
3 |
T16350 |
34412-34415 |
NN |
denotes |
min |
T16351 |
34415-34416 |
-RRB- |
denotes |
) |
T16352 |
34417-34420 |
CC |
denotes |
and |
T16353 |
34421-34425 |
RB |
denotes |
then |
T16354 |
34426-34432 |
VB |
denotes |
washed |
T16355 |
34433-34435 |
IN |
denotes |
in |
T16356 |
34436-34439 |
NNP |
denotes |
PBS |
T16357 |
34441-34445 |
RB |
denotes |
Next |
T16358 |
34445-34446 |
-COMMA- |
denotes |
, |
T16359 |
34447-34450 |
DT |
denotes |
the |
T16360 |
34451-34462 |
NN |
denotes |
lymphocytes |
T16361 |
34463-34467 |
VB |
denotes |
were |
T16362 |
34468-34477 |
VB |
denotes |
incubated |
T16363 |
34478-34482 |
IN |
denotes |
with |
T16364 |
34483-34490 |
JJ |
denotes |
various |
T16365 |
34491-34501 |
VB |
denotes |
conjugated |
T16366 |
34502-34512 |
JJ |
denotes |
monoclonal |
T16367 |
34513-34523 |
NN |
denotes |
antibodies |
T16368 |
34523-34524 |
-COMMA- |
denotes |
, |
T16369 |
34525-34534 |
VB |
denotes |
including |
T16370 |
34535-34542 |
NN |
denotes |
CD4-APC |
T16371 |
34542-34543 |
-COMMA- |
denotes |
, |
T16372 |
34544-34552 |
NN |
denotes |
CD8-FITC |
T16373 |
34553-34556 |
CC |
denotes |
and |
T16374 |
34557-34564 |
NN |
denotes |
CD19-PE |
T16375 |
34565-34568 |
IN |
denotes |
for |
T16376 |
34569-34574 |
NN |
denotes |
20min |
T16377 |
34575-34577 |
IN |
denotes |
at |
T16378 |
34578-34581 |
NN |
denotes |
4°C |
T16379 |
34581-34582 |
-COMMA- |
denotes |
, |
T16380 |
34583-34589 |
VB |
denotes |
washed |
T16381 |
34590-34595 |
RB |
denotes |
twice |
T16382 |
34596-34598 |
IN |
denotes |
in |
T16383 |
34599-34602 |
NNP |
denotes |
PBS |
T16384 |
34602-34603 |
-COMMA- |
denotes |
, |
T16385 |
34604-34607 |
CC |
denotes |
and |
T16386 |
34608-34620 |
JJ |
denotes |
re-suspended |
T16387 |
34621-34623 |
IN |
denotes |
in |
T16388 |
34624-34627 |
CD |
denotes |
400 |
T16389 |
34628-34630 |
NN |
denotes |
µl |
T16390 |
34631-34633 |
IN |
denotes |
of |
T16391 |
34634-34637 |
NNP |
denotes |
PBS |
T16392 |
34639-34640 |
DT |
denotes |
A |
T16393 |
34641-34645 |
NN |
denotes |
flow |
T16394 |
34646-34656 |
JJ |
denotes |
cytometric |
T16395 |
34657-34665 |
NN |
denotes |
analysis |
T16396 |
34666-34669 |
VB |
denotes |
was |
T16397 |
34670-34679 |
VB |
denotes |
performed |
T16398 |
34680-34682 |
IN |
denotes |
on |
T16399 |
34683-34684 |
DT |
denotes |
a |
T16400 |
34685-34693 |
NN |
denotes |
FACSAria |
T16401 |
34694-34698 |
NN |
denotes |
flow |
T16402 |
34699-34708 |
NN |
denotes |
cytometry |
T16403 |
34709-34710 |
-LRB- |
denotes |
( |
T16404 |
34710-34712 |
NN |
denotes |
BD |
T16405 |
34713-34724 |
NNP |
denotes |
Biosciences |
T16406 |
34724-34725 |
-RRB- |
denotes |
) |
T16407 |
34725-34726 |
-COMMA- |
denotes |
, |
T16408 |
34727-34730 |
CC |
denotes |
and |
T16409 |
34731-34734 |
DT |
denotes |
the |
T16410 |
34735-34739 |
NN |
denotes |
data |
T16411 |
34740-34744 |
VB |
denotes |
were |
T16412 |
34745-34753 |
VB |
denotes |
analyzed |
T16413 |
34754-34759 |
VB |
denotes |
using |
T16414 |
34760-34763 |
DT |
denotes |
the |
T16415 |
34764-34770 |
NNP |
denotes |
WinMDI |
T16416 |
34771-34782 |
JJ |
denotes |
statistical |
T16417 |
34783-34791 |
NN |
denotes |
software |
T16418 |
34792-34793 |
-LRB- |
denotes |
( |
T16419 |
34793-34800 |
NNP |
denotes |
Scripps |
T16420 |
34800-34801 |
-COMMA- |
denotes |
, |
T16421 |
34802-34804 |
NNP |
denotes |
La |
T16422 |
34805-34810 |
NNP |
denotes |
Jolla |
T16423 |
34810-34811 |
-COMMA- |
denotes |
, |
T16424 |
34812-34814 |
NNP |
denotes |
CA |
T16425 |
34814-34815 |
-COMMA- |
denotes |
, |
T16426 |
34816-34819 |
NNP |
denotes |
USA |
T16427 |
34819-34820 |
-RRB- |
denotes |
) |
T16428 |
34822-34829 |
RB |
denotes |
Forward |
T16429 |
34830-34833 |
CC |
denotes |
and |
T16430 |
34834-34838 |
NN |
denotes |
side |
T16431 |
34839-34846 |
NN |
denotes |
scatter |
T16432 |
34847-34857 |
NN |
denotes |
parameters |
T16433 |
34858-34862 |
VB |
denotes |
were |
T16434 |
34863-34867 |
VB |
denotes |
used |
T16435 |
34868-34870 |
TO |
denotes |
to |
T16436 |
34871-34875 |
VB |
denotes |
gate |
T16437 |
34876-34878 |
IN |
denotes |
on |
T16438 |
34879-34890 |
NN |
denotes |
lymphocytes |
T16734 |
34893-34900 |
NN |
denotes |
Protein |
T16735 |
34901-34914 |
NN |
denotes |
Immuno-arrays |
T16736 |
34915-34918 |
DT |
denotes |
The |
T16737 |
34919-34924 |
NN |
denotes |
tumor |
T16738 |
34925-34928 |
CC |
denotes |
and |
T16739 |
34929-34935 |
NN |
denotes |
spleen |
T16740 |
34936-34943 |
NN |
denotes |
tissues |
T16741 |
34944-34948 |
VB |
denotes |
were |
T16742 |
34949-34956 |
VB |
denotes |
excised |
T16743 |
34957-34960 |
CC |
denotes |
and |
T16744 |
34961-34972 |
VB |
denotes |
homogenized |
T16745 |
34973-34975 |
IN |
denotes |
in |
T16746 |
34976-34979 |
NNP |
denotes |
PBS |
T16747 |
34980-34984 |
IN |
denotes |
with |
T16748 |
34985-34993 |
NN |
denotes |
protease |
T16749 |
34994-35003 |
NN |
denotes |
inhibitor |
T16750 |
35004-35012 |
NN |
denotes |
cocktail |
T16751 |
35013-35014 |
-LRB- |
denotes |
( |
T16752 |
35014-35027 |
NNP |
denotes |
Sigma-Aldrich |
T16753 |
35027-35028 |
-COMMA- |
denotes |
, |
T16754 |
35029-35032 |
NNP |
denotes |
USA |
T16755 |
35032-35033 |
-RRB- |
denotes |
) |
T16756 |
35034-35037 |
CC |
denotes |
and |
T16757 |
35038-35044 |
NN |
denotes |
Triton |
T16758 |
35045-35050 |
NN |
denotes |
X-100 |
T16759 |
35051-35052 |
-LRB- |
denotes |
( |
T16760 |
35052-35057 |
JJ |
denotes |
final |
T16761 |
35058-35071 |
NN |
denotes |
concentration |
T16762 |
35072-35073 |
CD |
denotes |
1 |
T16763 |
35073-35074 |
NN |
denotes |
% |
T16764 |
35074-35075 |
-RRB- |
denotes |
) |
T16765 |
35077-35080 |
DT |
denotes |
The |
T16766 |
35081-35088 |
NN |
denotes |
samples |
T16767 |
35089-35093 |
VB |
denotes |
were |
T16768 |
35094-35100 |
VB |
denotes |
frozen |
T16769 |
35101-35103 |
IN |
denotes |
at |
T16770 |
35104-35109 |
NN |
denotes |
−70°C |
T16771 |
35109-35110 |
-COMMA- |
denotes |
, |
T16772 |
35111-35117 |
VB |
denotes |
thawed |
T16773 |
35117-35118 |
-COMMA- |
denotes |
, |
T16774 |
35119-35122 |
CC |
denotes |
and |
T16775 |
35123-35134 |
VB |
denotes |
centrifuged |
T16776 |
35135-35137 |
IN |
denotes |
at |
T16777 |
35138-35146 |
NN |
denotes |
10,000×g |
T16778 |
35147-35150 |
IN |
denotes |
for |
T16779 |
35151-35152 |
CD |
denotes |
5 |
T16780 |
35153-35156 |
NN |
denotes |
min |
T16781 |
35157-35159 |
TO |
denotes |
to |
T16782 |
35160-35166 |
VB |
denotes |
remove |
T16783 |
35167-35175 |
JJ |
denotes |
cellular |
T16784 |
35176-35182 |
NN |
denotes |
debris |
T16785 |
35184-35187 |
DT |
denotes |
The |
T16786 |
35188-35194 |
NN |
denotes |
tissue |
T16787 |
35195-35202 |
NN |
denotes |
lysates |
T16788 |
35203-35207 |
VB |
denotes |
were |
T16789 |
35208-35217 |
VB |
denotes |
performed |
T16790 |
35218-35225 |
NN |
denotes |
protein |
T16791 |
35226-35231 |
NN |
denotes |
assay |
T16792 |
35232-35234 |
IN |
denotes |
in |
T16793 |
35235-35238 |
DT |
denotes |
the |
T16794 |
35239-35243 |
JJ |
denotes |
same |
T16795 |
35244-35247 |
NN |
denotes |
way |
T16796 |
35248-35250 |
IN |
denotes |
as |
T16797 |
35251-35254 |
IN |
denotes |
for |
T16798 |
35255-35262 |
JJ |
denotes |
western |
T16799 |
35263-35271 |
NN |
denotes |
blotting |
T16800 |
35273-35276 |
CD |
denotes |
4.5 |
T16801 |
35277-35279 |
NN |
denotes |
mg |
T16802 |
35280-35282 |
IN |
denotes |
of |
T16803 |
35283-35291 |
NN |
denotes |
proteins |
T16804 |
35291-35292 |
-COMMA- |
denotes |
, |
T16805 |
35293-35302 |
VB |
denotes |
collected |
T16806 |
35303-35307 |
IN |
denotes |
from |
T16807 |
35308-35313 |
CD |
denotes |
three |
T16808 |
35314-35321 |
NN |
denotes |
samples |
T16809 |
35322-35325 |
IN |
denotes |
per |
T16810 |
35326-35331 |
NN |
denotes |
group |
T16811 |
35331-35332 |
-COMMA- |
denotes |
, |
T16812 |
35333-35337 |
VB |
denotes |
were |
T16813 |
35338-35342 |
VB |
denotes |
used |
T16814 |
35343-35346 |
IN |
denotes |
for |
T16815 |
35347-35352 |
NN |
denotes |
Mouse |
T16816 |
35353-35361 |
NN |
denotes |
cytokine |
T16817 |
35362-35367 |
NN |
denotes |
array |
T16818 |
35368-35370 |
IN |
denotes |
as |
T16819 |
35371-35374 |
DT |
denotes |
the |
T16820 |
35375-35383 |
NN |
denotes |
protocol |
T16821 |
35384-35392 |
VB |
denotes |
provided |
T16822 |
35393-35395 |
IN |
denotes |
by |
T16823 |
35396-35404 |
NN |
denotes |
supplier |
T16824 |
35405-35406 |
-LRB- |
denotes |
( |
T16825 |
35406-35414 |
NNP |
denotes |
Proteome |
T16826 |
35415-35424 |
NNP |
denotes |
Profiler™ |
T16827 |
35424-35425 |
-COMMA- |
denotes |
, |
T16828 |
35426-35427 |
-SHARP- |
denotes |
# |
T16829 |
35427-35433 |
NN |
denotes |
ARY006 |
T16830 |
35433-35434 |
-COMMA- |
denotes |
, |
T16831 |
35435-35436 |
NNP |
denotes |
R |
T16832 |
35436-35437 |
CC |
denotes |
& |
T16833 |
35437-35438 |
NNP |
denotes |
D |
T16834 |
35439-35446 |
NNP |
denotes |
Systems |
T16835 |
35446-35447 |
-COMMA- |
denotes |
, |
T16836 |
35448-35451 |
NNP |
denotes |
USA |
T16837 |
35451-35452 |
-RRB- |
denotes |
) |
T16985 |
35455-35466 |
JJ |
denotes |
Statistical |
T16986 |
35467-35475 |
NN |
denotes |
Analysis |
T16987 |
35476-35479 |
DT |
denotes |
The |
T16988 |
35480-35484 |
NN |
denotes |
data |
T16989 |
35485-35489 |
VB |
denotes |
were |
T16990 |
35490-35498 |
VB |
denotes |
analyzed |
T16991 |
35499-35504 |
VB |
denotes |
using |
T16992 |
35505-35508 |
DT |
denotes |
the |
T16993 |
35509-35517 |
NNP |
denotes |
GraphPad |
T16994 |
35518-35523 |
NNP |
denotes |
Prism |
T16995 |
35524-35525 |
CD |
denotes |
4 |
T16996 |
35526-35529 |
NN |
denotes |
ver |
T16997 |
35531-35535 |
CD |
denotes |
4.03 |
T16998 |
35536-35544 |
NN |
denotes |
software |
T16999 |
35545-35546 |
-LRB- |
denotes |
( |
T17000 |
35546-35554 |
NNP |
denotes |
GraphPad |
T17001 |
35555-35563 |
NNP |
denotes |
Software |
T17002 |
35563-35564 |
-COMMA- |
denotes |
, |
T17003 |
35565-35567 |
NNP |
denotes |
La |
T17004 |
35568-35573 |
NNP |
denotes |
Jolla |
T17005 |
35573-35574 |
-COMMA- |
denotes |
, |
T17006 |
35575-35577 |
NNP |
denotes |
CA |
T17007 |
35577-35578 |
-RRB- |
denotes |
) |
T17008 |
35580-35584 |
NN |
denotes |
Data |
T17009 |
35585-35588 |
VB |
denotes |
are |
T17010 |
35589-35598 |
VB |
denotes |
presented |
T17011 |
35599-35601 |
IN |
denotes |
as |
T17012 |
35602-35606 |
JJ |
denotes |
mean |
T17013 |
35607-35608 |
NN |
denotes |
± |
T17014 |
35609-35611 |
NN |
denotes |
SD |
T17015 |
35613-35623 |
NN |
denotes |
Difference |
T17016 |
35624-35631 |
IN |
denotes |
between |
T17017 |
35632-35639 |
NN |
denotes |
CCR5−/− |
T17018 |
35640-35644 |
NN |
denotes |
mice |
T17019 |
35645-35648 |
CC |
denotes |
and |
T17020 |
35649-35656 |
JJ |
denotes |
CCR5+/+ |
T17021 |
35657-35661 |
NN |
denotes |
mice |
T17022 |
35662-35666 |
VB |
denotes |
were |
T17023 |
35667-35675 |
VB |
denotes |
compared |
T17024 |
35676-35681 |
VB |
denotes |
using |
T17025 |
35682-35683 |
NN |
denotes |
t |
T17026 |
35684-35688 |
NN |
denotes |
test |
T17027 |
35690-35691 |
DT |
denotes |
A |
T17028 |
35692-35697 |
NN |
denotes |
value |
T17029 |
35698-35700 |
IN |
denotes |
of |
T17030 |
35701-35702 |
NN |
denotes |
p |
T17031 |
35702-35703 |
SYM |
denotes |
< |
T17032 |
35703-35707 |
CD |
denotes |
0.05 |
T17033 |
35708-35711 |
VB |
denotes |
was |
T17034 |
35712-35722 |
VB |
denotes |
considered |
T17035 |
35723-35725 |
TO |
denotes |
to |
T17036 |
35726-35728 |
VB |
denotes |
be |
T17037 |
35729-35742 |
RB |
denotes |
statistically |
T17038 |
35743-35754 |
JJ |
denotes |
significant |
T17039 |
35756-35764 |
NN |
denotes |
Survival |
T17040 |
35765-35769 |
NN |
denotes |
data |
T17041 |
35770-35774 |
VB |
denotes |
were |
T17042 |
35775-35784 |
VB |
denotes |
presented |
T17043 |
35785-35787 |
IN |
denotes |
by |
T17044 |
35788-35800 |
NNP |
denotes |
Kaplan-Meier |
T17045 |
35801-35809 |
NN |
denotes |
survival |
T17046 |
35810-35819 |
NN |
denotes |
estimates |
T17047 |
35820-35823 |
CC |
denotes |
and |
T17048 |
35824-35832 |
VB |
denotes |
compared |
T17049 |
35833-35836 |
CC |
denotes |
and |
T17050 |
35837-35847 |
VB |
denotes |
calculated |
T17051 |
35848-35850 |
IN |
denotes |
by |
T17052 |
35851-35859 |
NNP |
denotes |
Log-rank |
T17053 |
35860-35861 |
-LRB- |
denotes |
( |
T17054 |
35861-35871 |
JJ |
denotes |
Mantel-Cox |
T17055 |
35871-35872 |
-RRB- |
denotes |
) |
T17056 |
35873-35877 |
NN |
denotes |
Test |
T17057 |
35878-35880 |
IN |
denotes |
in |
T17058 |
35881-35889 |
NNP |
denotes |
GraphPad |
T17059 |
35890-35895 |
NNP |
denotes |
Prism |
R100 |
T317 |
T329 |
arg1Of |
showed,when |
R1000 |
T1926 |
T1925 |
arg2Of |
demonstrated,been |
R1001 |
T1928 |
T1926 |
arg3Of |
inhibit,demonstrated |
R1002 |
T1928 |
T1927 |
arg1Of |
inhibit,to |
R1003 |
T1928 |
T1937 |
arg1Of |
inhibit,[ |
R1004 |
T1931 |
T1929 |
arg1Of |
growth,experimental |
R1005 |
T1931 |
T1930 |
arg1Of |
growth,tumor |
R1006 |
T1931 |
T1932 |
arg1Of |
growth,and |
R1007 |
T1932 |
T1928 |
arg2Of |
and,inhibit |
R1008 |
T1933 |
T1932 |
arg2Of |
metastasis,and |
R1009 |
T1933 |
T1934 |
arg1Of |
metastasis,of |
R101 |
T320 |
T318 |
arg2Of |
volume,reduced |
R1010 |
T1936 |
T1934 |
arg2Of |
cancer,of |
R1011 |
T1936 |
T1935 |
arg1Of |
cancer,pancreatic |
R1012 |
T1938 |
T1937 |
arg2Of |
9,[ |
R1013 |
T1939 |
T1937 |
arg3Of |
],[ |
R1014 |
T1941 |
T1940 |
arg2Of |
addition,In |
R1015 |
T1944 |
T1943 |
arg1Of |
absence,host |
R1016 |
T1944 |
T1945 |
arg1Of |
absence,of |
R1017 |
T1944 |
T1947 |
arg1Of |
absence,potentiates |
R1018 |
T1946 |
T1945 |
arg2Of |
CCR5,of |
R1019 |
T1947 |
T1957 |
arg1Of |
potentiates,and |
R102 |
T320 |
T319 |
arg1Of |
volume,tumor |
R1020 |
T1949 |
T1947 |
arg2Of |
delay,potentiates |
R1021 |
T1949 |
T1948 |
arg1Of |
delay,the |
R1022 |
T1949 |
T1950 |
arg1Of |
delay,of |
R10220 |
T14695 |
T14694 |
arg1Of |
specimens,All |
R10221 |
T14695 |
T14696 |
arg1Of |
specimens,were |
R10222 |
T14695 |
T14697 |
arg2Of |
specimens,fixed |
R10223 |
T14695 |
T14701 |
arg2Of |
specimens,embedded |
R10224 |
T14697 |
T14698 |
arg1Of |
fixed,in |
R10225 |
T14697 |
T14700 |
arg1Of |
fixed,and |
R10226 |
T14699 |
T14698 |
arg2Of |
formalin,in |
R10227 |
T14700 |
T14696 |
arg2Of |
and,were |
R10228 |
T14701 |
T14700 |
arg2Of |
embedded,and |
R10229 |
T14701 |
T14702 |
arg1Of |
embedded,in |
R1023 |
T1952 |
T1950 |
arg2Of |
growth,of |
R10230 |
T14703 |
T14702 |
arg2Of |
paraffin,in |
R10231 |
T14703 |
T14704 |
arg1Of |
paraffin,for |
R10232 |
T14705 |
T14704 |
arg2Of |
examination,for |
R10233 |
T14706 |
T14707 |
arg1Of |
Sections,( |
R10234 |
T14706 |
T14712 |
arg1Of |
Sections,were |
R10235 |
T14706 |
T14713 |
arg2Of |
Sections,stained |
R10236 |
T14706 |
T14719 |
arg2Of |
Sections,analyzed |
R10237 |
T14709 |
T14707 |
arg2Of |
µm,( |
R10238 |
T14709 |
T14708 |
arg1Of |
µm,4 |
R10239 |
T14709 |
T14710 |
arg1Of |
µm,thick |
R1024 |
T1952 |
T1951 |
arg1Of |
growth,tumor |
R10240 |
T14711 |
T14707 |
arg3Of |
),( |
R10241 |
T14713 |
T14714 |
arg1Of |
stained,with |
R10242 |
T14713 |
T14718 |
arg1Of |
stained,and |
R10243 |
T14717 |
T14714 |
arg2Of |
E,with |
R10244 |
T14717 |
T14715 |
arg1Of |
E,H |
R10245 |
T14717 |
T14716 |
arg1Of |
E,& |
R10246 |
T14718 |
T14712 |
arg2Of |
and,were |
R10247 |
T14719 |
T14718 |
arg2Of |
analyzed,and |
R10248 |
T14721 |
T14719 |
arg1Of |
immunohistochemistry,analyzed |
R10249 |
T14721 |
T14720 |
arg2Of |
immunohistochemistry,by |
R1025 |
T1952 |
T1953 |
arg1Of |
growth,[ |
R10250 |
T14724 |
T14722 |
arg1Of |
sections,The |
R10251 |
T14724 |
T14723 |
arg1Of |
sections,paraffin-embedded |
R10252 |
T14724 |
T14725 |
arg1Of |
sections,were |
R10253 |
T14724 |
T14726 |
arg2Of |
sections,deparaffinized |
R10254 |
T14724 |
T14728 |
arg2Of |
sections,rehydrated |
R10255 |
T14724 |
T14730 |
arg2Of |
sections,washed |
R10256 |
T14724 |
T14737 |
arg2Of |
sections,subjected |
R10257 |
T14726 |
T14727 |
arg1Of |
deparaffinized,and |
R10258 |
T14727 |
T14729 |
arg1Of |
and,"," |
R10259 |
T14728 |
T14727 |
arg2Of |
rehydrated,and |
R1026 |
T1954 |
T1953 |
arg2Of |
10,[ |
R10260 |
T14729 |
T14735 |
arg1Of |
",",and |
R10261 |
T14730 |
T14729 |
arg2Of |
washed,"," |
R10262 |
T14730 |
T14731 |
arg1Of |
washed,in |
R10263 |
T14733 |
T14731 |
arg2Of |
water,in |
R10264 |
T14733 |
T14732 |
arg1Of |
water,distilled |
R10265 |
T14735 |
T14725 |
arg2Of |
and,were |
R10266 |
T14735 |
T14734 |
arg1Of |
and,"," |
R10267 |
T14737 |
T14735 |
arg2Of |
subjected,and |
R10268 |
T14737 |
T14736 |
arg1Of |
subjected,then |
R10269 |
T14737 |
T14738 |
arg1Of |
subjected,to |
R1027 |
T1955 |
T1953 |
arg3Of |
],[ |
R10270 |
T14741 |
T14738 |
arg2Of |
retrieval,to |
R10271 |
T14741 |
T14739 |
arg1Of |
retrieval,heat-mediated |
R10272 |
T14741 |
T14740 |
arg1Of |
retrieval,antigen |
R10273 |
T14744 |
T14742 |
arg1Of |
activity,Endogenous |
R10274 |
T14744 |
T14743 |
arg1Of |
activity,peroxidase |
R10275 |
T14744 |
T14745 |
arg1Of |
activity,was |
R10276 |
T14744 |
T14746 |
arg2Of |
activity,quenched |
R10277 |
T14746 |
T14745 |
arg2Of |
quenched,was |
R10278 |
T14746 |
T14759 |
arg1Of |
quenched,"," |
R10279 |
T14746 |
T14760 |
modOf |
quenched,followed |
R1028 |
T1957 |
T1940 |
arg1Of |
and,In |
R10280 |
T14748 |
T14746 |
arg1Of |
incubation,quenched |
R10281 |
T14748 |
T14747 |
arg2Of |
incubation,by |
R10282 |
T14748 |
T14749 |
arg1Of |
incubation,in |
R10283 |
T14753 |
T14749 |
arg2Of |
peroxide,in |
R10284 |
T14753 |
T14750 |
arg1Of |
peroxide,3 |
R10285 |
T14753 |
T14751 |
arg1Of |
peroxide,% |
R10286 |
T14753 |
T14752 |
arg1Of |
peroxide,hydrogen |
R10287 |
T14753 |
T14754 |
arg1Of |
peroxide,in |
R10288 |
T14753 |
T14756 |
arg1Of |
peroxide,for |
R10289 |
T14755 |
T14754 |
arg2Of |
methanol,in |
R1029 |
T1957 |
T1942 |
arg1Of |
and,"," |
R10290 |
T14758 |
T14756 |
arg2Of |
min,for |
R10291 |
T14758 |
T14757 |
arg1Of |
min,15 |
R10292 |
T14760 |
T14761 |
arg1Of |
followed,by |
R10293 |
T14762 |
T14761 |
arg2Of |
clearing,by |
R10294 |
T14762 |
T14763 |
arg1Of |
clearing,in |
R10295 |
T14762 |
T14765 |
arg1Of |
clearing,for |
R10296 |
T14764 |
T14763 |
arg2Of |
PBS,in |
R10297 |
T14767 |
T14765 |
arg2Of |
min,for |
R10298 |
T14767 |
T14766 |
arg1Of |
min,5 |
R10299 |
T14769 |
T14768 |
arg1Of |
sections,The |
R103 |
T320 |
T321 |
arg1Of |
volume,"," |
R1030 |
T1957 |
T1956 |
arg1Of |
and,"," |
R10300 |
T14769 |
T14770 |
arg1Of |
sections,were |
R10301 |
T14769 |
T14771 |
arg2Of |
sections,blocked |
R10302 |
T14769 |
T14788 |
arg2Of |
sections,incubated |
R10303 |
T14771 |
T14772 |
arg1Of |
blocked,for |
R10304 |
T14771 |
T14787 |
arg1Of |
blocked,and |
R10305 |
T14774 |
T14772 |
arg2Of |
min,for |
R10306 |
T14774 |
T14773 |
arg1Of |
min,30 |
R10307 |
T14774 |
T14775 |
arg1Of |
min,with |
R10308 |
T14776 |
T14777 |
arg1Of |
3,% |
R10309 |
T14780 |
T14775 |
arg2Of |
serum,with |
R1031 |
T1959 |
T1958 |
arg1Of |
inhibitors,CCR5 |
R10310 |
T14780 |
T14776 |
arg1Of |
serum,3 |
R10311 |
T14780 |
T14778 |
arg1Of |
serum,normal |
R10312 |
T14780 |
T14779 |
arg1Of |
serum,horse |
R10313 |
T14780 |
T14781 |
arg2Of |
serum,diluted |
R10314 |
T14781 |
T14782 |
arg1Of |
diluted,in |
R10315 |
T14783 |
T14782 |
arg2Of |
PBS,in |
R10316 |
T14783 |
T14784 |
arg1Of |
PBS,"," |
R10317 |
T14783 |
T14785 |
arg2Of |
PBS,blotted |
R10318 |
T14787 |
T14770 |
arg2Of |
and,were |
R10319 |
T14787 |
T14786 |
arg1Of |
and,"," |
R1032 |
T1959 |
T1960 |
arg1Of |
inhibitors,prevented |
R10320 |
T14788 |
T14787 |
arg2Of |
incubated,and |
R10321 |
T14788 |
T14789 |
arg1Of |
incubated,with |
R10322 |
T14791 |
T14792 |
arg2Of |
mouse,anti-mouse |
R10323 |
T14796 |
T14792 |
arg3Of |
antigen,anti-mouse |
R10324 |
T14796 |
T14793 |
arg1Of |
antigen,proliferating |
R10325 |
T14796 |
T14794 |
arg1Of |
antigen,cell |
R10326 |
T14796 |
T14795 |
arg1Of |
antigen,nuclear |
R10327 |
T14796 |
T14797 |
arg1Of |
antigen,( |
R10328 |
T14798 |
T14797 |
arg2Of |
PCNA,( |
R10329 |
T14798 |
T14799 |
arg1Of |
PCNA,"," |
R1033 |
T1960 |
T1957 |
arg2Of |
prevented,and |
R10330 |
T14801 |
T14799 |
arg2Of |
dilution,"," |
R10331 |
T14801 |
T14800 |
arg1Of |
dilution,1∶200 |
R10332 |
T14802 |
T14797 |
arg3Of |
),( |
R10333 |
T14804 |
T14789 |
arg2Of |
antibodies,with |
R10334 |
T14804 |
T14790 |
arg1Of |
antibodies,primary |
R10335 |
T14804 |
T14791 |
arg1Of |
antibodies,mouse |
R10336 |
T14804 |
T14803 |
arg1Of |
antibodies,monoclonal |
R10337 |
T14804 |
T14805 |
arg1Of |
antibodies,in |
R10338 |
T14806 |
T14805 |
arg2Of |
blocking,in |
R10339 |
T14806 |
T14808 |
arg1Of |
blocking,for |
R1034 |
T1963 |
T1960 |
arg2Of |
growth,prevented |
R10340 |
T14806 |
T14811 |
arg1Of |
blocking,at |
R10341 |
T14807 |
T14806 |
arg2Of |
serum,blocking |
R10342 |
T14810 |
T14808 |
arg2Of |
h,for |
R10343 |
T14810 |
T14809 |
arg1Of |
h,4 |
R10344 |
T14813 |
T14811 |
arg2Of |
temperature,at |
R10345 |
T14813 |
T14812 |
arg1Of |
temperature,room |
R10346 |
T14817 |
T14816 |
arg1Of |
slides,the |
R10347 |
T14817 |
T14818 |
arg1Of |
slides,were |
R10348 |
T14817 |
T14819 |
arg2Of |
slides,washed |
R10349 |
T14817 |
T14829 |
arg2Of |
slides,incubated |
R1035 |
T1963 |
T1961 |
arg1Of |
growth,cancer |
R10350 |
T14819 |
T14821 |
arg1Of |
washed,times |
R10351 |
T14819 |
T14822 |
arg1Of |
washed,for |
R10352 |
T14819 |
T14828 |
arg1Of |
washed,and |
R10353 |
T14821 |
T14820 |
arg1Of |
times,three |
R10354 |
T14824 |
T14822 |
arg2Of |
min,for |
R10355 |
T14824 |
T14823 |
arg1Of |
min,5 |
R10356 |
T14824 |
T14825 |
arg1Of |
min,each |
R10357 |
T14824 |
T14826 |
arg1Of |
min,in |
R10358 |
T14827 |
T14826 |
arg2Of |
PBS,in |
R10359 |
T14828 |
T14814 |
arg1Of |
and,Thereafter |
R1036 |
T1963 |
T1962 |
arg1Of |
growth,cell |
R10360 |
T14828 |
T14815 |
arg1Of |
and,"," |
R10361 |
T14828 |
T14818 |
arg2Of |
and,were |
R10362 |
T14829 |
T14828 |
arg2Of |
incubated,and |
R10363 |
T14829 |
T14830 |
arg1Of |
incubated,with |
R10364 |
T14832 |
T14833 |
arg1Of |
anti-mouse,and |
R10365 |
T14834 |
T14833 |
arg2Of |
anti-rabbit,and |
R10366 |
T14835 |
T14830 |
arg2Of |
antibodies,with |
R10367 |
T14835 |
T14831 |
arg2Of |
antibodies,biotinylated |
R10368 |
T14835 |
T14832 |
arg1Of |
antibodies,anti-mouse |
R10369 |
T14835 |
T14834 |
arg1Of |
antibodies,anti-rabbit |
R1037 |
T1963 |
T1964 |
arg1Of |
growth,"," |
R10370 |
T14835 |
T14836 |
arg1Of |
antibodies,for |
R10371 |
T14838 |
T14836 |
arg2Of |
h,for |
R10372 |
T14838 |
T14837 |
arg1Of |
h,2 |
R10373 |
T14840 |
T14839 |
arg1Of |
slides,The |
R10374 |
T14840 |
T14841 |
arg1Of |
slides,were |
R10375 |
T14840 |
T14842 |
arg2Of |
slides,washed |
R10376 |
T14842 |
T14841 |
arg2Of |
washed,were |
R10377 |
T14842 |
T14843 |
arg1Of |
washed,in |
R10378 |
T14844 |
T14843 |
arg2Of |
PBS,in |
R10379 |
T14844 |
T14845 |
arg1Of |
PBS,"," |
R1038 |
T1963 |
T1966 |
arg1Of |
growth,as |
R10380 |
T14844 |
T14846 |
arg2Of |
PBS,followed |
R10381 |
T14844 |
T14856 |
arg1Of |
PBS,( |
R10382 |
T14849 |
T14846 |
arg1Of |
addition,followed |
R10383 |
T14849 |
T14847 |
arg2Of |
addition,by |
R10384 |
T14849 |
T14848 |
arg1Of |
addition,the |
R10385 |
T14849 |
T14850 |
arg1Of |
addition,of |
R10386 |
T14855 |
T14850 |
arg2Of |
complex,of |
R10387 |
T14855 |
T14851 |
arg1Of |
complex,the |
R10388 |
T14855 |
T14852 |
arg1Of |
complex,avidin |
R10389 |
T14855 |
T14853 |
arg1Of |
complex,biotin |
R1039 |
T1966 |
T1965 |
arg1Of |
as,such |
R10390 |
T14855 |
T14854 |
arg1Of |
complex,peroxidase |
R10391 |
T14858 |
T14857 |
arg1Of |
kit,ABC |
R10392 |
T14858 |
T14859 |
arg1Of |
kit,; |
R10393 |
T14859 |
T14856 |
arg2Of |
;,( |
R10394 |
T14859 |
T14866 |
arg1Of |
;,"," |
R10395 |
T14859 |
T14867 |
arg1Of |
;,USA |
R10396 |
T14861 |
T14860 |
arg1Of |
Laboratories,Vector |
R10397 |
T14861 |
T14862 |
arg1Of |
Laboratories,"," |
R10398 |
T14862 |
T14864 |
arg1Of |
",","," |
R10399 |
T14863 |
T14862 |
arg2Of |
Burlingame,"," |
R104 |
T321 |
T325 |
arg1Of |
",",and |
R1040 |
T1968 |
T1967 |
arg1Of |
cancer,prostate |
R10400 |
T14864 |
T14859 |
arg2Of |
",",; |
R10401 |
T14865 |
T14864 |
arg2Of |
CA,"," |
R10402 |
T14868 |
T14856 |
arg3Of |
),( |
R10403 |
T14870 |
T14869 |
arg1Of |
slides,The |
R10404 |
T14870 |
T14871 |
arg1Of |
slides,were |
R10405 |
T14870 |
T14872 |
arg2Of |
slides,washed |
R10406 |
T14872 |
T14871 |
arg2Of |
washed,were |
R10407 |
T14872 |
T14873 |
arg1Of |
washed,and |
R10408 |
T14876 |
T14874 |
arg1Of |
reaction,the |
R10409 |
T14876 |
T14875 |
arg1Of |
reaction,peroxidase |
R1041 |
T1968 |
T1969 |
arg1Of |
cancer,[ |
R10410 |
T14876 |
T14877 |
arg1Of |
reaction,was |
R10411 |
T14876 |
T14878 |
arg2Of |
reaction,developed |
R10412 |
T14878 |
T14873 |
arg2Of |
developed,and |
R10413 |
T14878 |
T14877 |
arg2Of |
developed,was |
R10414 |
T14878 |
T14879 |
arg1Of |
developed,with |
R10415 |
T14878 |
T14886 |
arg1Of |
developed,"," |
R10416 |
T14878 |
T14887 |
modOf |
developed,followed |
R10417 |
T14880 |
T14881 |
arg1Of |
diaminobenzidine,( |
R10418 |
T14880 |
T14884 |
arg1Of |
diaminobenzidine,and |
R10419 |
T14882 |
T14881 |
arg2Of |
DAB,( |
R1042 |
T1968 |
T1972 |
arg1Of |
cancer,"," |
R10420 |
T14883 |
T14881 |
arg3Of |
),( |
R10421 |
T14884 |
T14879 |
arg2Of |
and,with |
R10422 |
T14885 |
T14884 |
arg2Of |
peroxide,and |
R10423 |
T14889 |
T14890 |
arg1Of |
counterstaining,with |
R10424 |
T14889 |
T14892 |
arg1Of |
counterstaining,"," |
R10425 |
T14889 |
T14893 |
modOf |
counterstaining,mounting |
R10426 |
T14889 |
T14897 |
arg1Of |
counterstaining,and |
R10427 |
T14891 |
T14890 |
arg2Of |
hematoxylin,with |
R10428 |
T14893 |
T14894 |
arg1Of |
mounting,in |
R10429 |
T14895 |
T14894 |
arg2Of |
aqua-mount,in |
R1043 |
T1970 |
T1969 |
arg2Of |
11,[ |
R10430 |
T14897 |
T14887 |
arg1Of |
and,followed |
R10431 |
T14897 |
T14888 |
arg2Of |
and,by |
R10432 |
T14897 |
T14896 |
arg1Of |
and,"," |
R10433 |
T14897 |
T14899 |
arg1Of |
and,under |
R10434 |
T14898 |
T14897 |
arg2Of |
evaluation,and |
R10435 |
T14902 |
T14899 |
arg2Of |
microscope,under |
R10436 |
T14902 |
T14900 |
arg1Of |
microscope,a |
R10437 |
T14902 |
T14901 |
arg1Of |
microscope,light |
R10438 |
T14902 |
T14903 |
arg1Of |
microscope,( |
R10439 |
T14904 |
T14903 |
arg2Of |
magnification×200,( |
R1044 |
T1971 |
T1969 |
arg3Of |
],[ |
R10440 |
T14904 |
T14905 |
arg1Of |
magnification×200,; |
R10441 |
T14906 |
T14905 |
arg2Of |
Olympus,; |
R10442 |
T14906 |
T14907 |
arg1Of |
Olympus,"," |
R10443 |
T14908 |
T14907 |
arg2Of |
Tokyo,"," |
R10444 |
T14908 |
T14909 |
arg1Of |
Tokyo,"," |
R10445 |
T14910 |
T14909 |
arg2Of |
Japan,"," |
R10446 |
T14911 |
T14903 |
arg3Of |
),( |
R10447 |
T14914 |
T14912 |
arg1Of |
control,A |
R10448 |
T14914 |
T14913 |
arg1Of |
control,negative |
R10449 |
T14914 |
T14915 |
arg1Of |
control,was |
R1045 |
T1972 |
T1975 |
arg1Of |
",","," |
R10450 |
T14914 |
T14916 |
arg2Of |
control,included |
R10451 |
T14914 |
T14921 |
arg1Of |
control,omitting |
R10452 |
T14916 |
T14915 |
arg2Of |
included,was |
R10453 |
T14916 |
T14917 |
arg1Of |
included,in |
R10454 |
T14916 |
T14920 |
arg1Of |
included,by |
R10455 |
T14919 |
T14917 |
arg2Of |
experiments,in |
R10456 |
T14919 |
T14918 |
arg1Of |
experiments,all |
R10457 |
T14921 |
T14920 |
arg2Of |
omitting,by |
R10458 |
T14924 |
T14921 |
arg2Of |
antibody,omitting |
R10459 |
T14924 |
T14922 |
arg1Of |
antibody,the |
R1046 |
T1974 |
T1972 |
arg2Of |
cancer,"," |
R10460 |
T14924 |
T14923 |
arg1Of |
antibody,primary |
R10461 |
T14927 |
T14925 |
arg2Of |
detection,For |
R10462 |
T14927 |
T14926 |
arg1Of |
detection,the |
R10463 |
T14927 |
T14928 |
arg1Of |
detection,of |
R10464 |
T14927 |
T14932 |
arg1Of |
detection,in |
R10465 |
T14931 |
T14928 |
arg2Of |
death,of |
R10466 |
T14931 |
T14929 |
arg1Of |
death,apoptotic |
R10467 |
T14931 |
T14930 |
arg1Of |
death,cell |
R10468 |
T14935 |
T14932 |
arg2Of |
tissues,in |
R10469 |
T14935 |
T14933 |
arg1Of |
tissues,the |
R1047 |
T1974 |
T1973 |
arg1Of |
cancer,breast |
R10470 |
T14935 |
T14934 |
arg1Of |
tissues,tumor |
R10471 |
T14939 |
T14937 |
arg1Of |
sections,the |
R10472 |
T14939 |
T14938 |
arg1Of |
sections,paraffin-embedded |
R10473 |
T14939 |
T14940 |
arg1Of |
sections,were |
R10474 |
T14939 |
T14941 |
arg2Of |
sections,incubated |
R10475 |
T14939 |
T14968 |
arg1Of |
sections,washed |
R10476 |
T14941 |
T14940 |
arg2Of |
incubated,were |
R10477 |
T14941 |
T14942 |
arg1Of |
incubated,in |
R10478 |
T14941 |
T14966 |
arg1Of |
incubated,and |
R10479 |
T14944 |
T14945 |
arg1Of |
mixture,of |
R1048 |
T1975 |
T1982 |
arg1Of |
",",and |
R10480 |
T14944 |
T14953 |
arg1Of |
mixture,and |
R10481 |
T14948 |
T14945 |
arg2Of |
solution,of |
R10482 |
T14948 |
T14946 |
arg1Of |
solution,the |
R10483 |
T14948 |
T14947 |
arg1Of |
solution,labeling |
R10484 |
T14948 |
T14949 |
arg1Of |
solution,( |
R10485 |
T14951 |
T14949 |
arg2Of |
µl,( |
R10486 |
T14951 |
T14950 |
arg1Of |
µl,540 |
R10487 |
T14952 |
T14949 |
arg3Of |
),( |
R10488 |
T14953 |
T14942 |
arg2Of |
and,in |
R10489 |
T14953 |
T14943 |
arg1Of |
and,a |
R1049 |
T1977 |
T1975 |
arg2Of |
cells,"," |
R10490 |
T14955 |
T14953 |
arg2Of |
solution,and |
R10491 |
T14955 |
T14954 |
arg1Of |
solution,enzyme |
R10492 |
T14955 |
T14956 |
arg1Of |
solution,( |
R10493 |
T14955 |
T14960 |
arg1Of |
solution,for |
R10494 |
T14958 |
T14956 |
arg2Of |
µl,( |
R10495 |
T14958 |
T14957 |
arg1Of |
µl,60 |
R10496 |
T14959 |
T14956 |
arg3Of |
),( |
R10497 |
T14962 |
T14960 |
arg2Of |
h,for |
R10498 |
T14962 |
T14961 |
arg1Of |
h,1 |
R10499 |
T14962 |
T14963 |
arg1Of |
h,at |
R105 |
T323 |
T321 |
arg2Of |
weight,"," |
R1050 |
T1977 |
T1976 |
arg1Of |
cells,hepatoma |
R10500 |
T14964 |
T14963 |
arg2Of |
37°C,at |
R10501 |
T14966 |
T14925 |
arg1Of |
and,For |
R10502 |
T14966 |
T14936 |
arg1Of |
and,"," |
R10503 |
T14966 |
T14965 |
arg1Of |
and,"," |
R10504 |
T14968 |
T14966 |
arg2Of |
washed,and |
R10505 |
T14968 |
T14967 |
arg1Of |
washed,then |
R10506 |
T14968 |
T14970 |
arg1Of |
washed,times |
R10507 |
T14968 |
T14971 |
arg1Of |
washed,in |
R10508 |
T14968 |
T14975 |
arg1Of |
washed,for |
R10509 |
T14968 |
T14979 |
arg1Of |
washed,"," |
R1051 |
T1977 |
T1978 |
arg1Of |
cells,[ |
R10510 |
T14968 |
T14980 |
arg1Of |
washed,according |
R10511 |
T14970 |
T14969 |
arg1Of |
times,three |
R10512 |
T14972 |
T14973 |
arg1Of |
0.1,M |
R10513 |
T14974 |
T14971 |
arg2Of |
PBS,in |
R10514 |
T14974 |
T14972 |
arg1Of |
PBS,0.1 |
R10515 |
T14977 |
T14975 |
arg2Of |
min,for |
R10516 |
T14977 |
T14976 |
arg1Of |
min,5 |
R10517 |
T14978 |
T14968 |
arg2Of |
each,washed |
R10518 |
T14981 |
T14980 |
arg2Of |
to,according |
R10519 |
T14984 |
T14981 |
arg2Of |
instructions,to |
R1052 |
T1979 |
T1978 |
arg2Of |
4,[ |
R10520 |
T14984 |
T14982 |
arg1Of |
instructions,the |
R10521 |
T14984 |
T14983 |
arg1Of |
instructions,manufacturer’s |
R10522 |
T14988 |
T14987 |
arg1Of |
sections,the |
R10523 |
T14988 |
T14989 |
arg1Of |
sections,were |
R10524 |
T14988 |
T14990 |
arg2Of |
sections,incubated |
R10525 |
T14988 |
T15010 |
arg2Of |
sections,mounted |
R10526 |
T14988 |
T15015 |
arg1Of |
sections,cover-slipped |
R10527 |
T14990 |
T14989 |
arg2Of |
incubated,were |
R10528 |
T14990 |
T14991 |
arg1Of |
incubated,with |
R10529 |
T14990 |
T14993 |
arg1Of |
incubated,"," |
R1053 |
T1980 |
T1978 |
arg3Of |
],[ |
R10530 |
T14992 |
T14991 |
arg2Of |
4′,with |
R10531 |
T14993 |
T14985 |
arg1Of |
",",Next |
R10532 |
T14993 |
T14986 |
arg1Of |
",","," |
R10533 |
T14993 |
T15010 |
modOf |
",",mounted |
R10534 |
T14993 |
T15015 |
modOf |
",",cover-slipped |
R10535 |
T14994 |
T14995 |
arg1Of |
6-diamidino-2-phenylindole,( |
R10536 |
T14994 |
T14998 |
arg1Of |
6-diamidino-2-phenylindole,for |
R10537 |
T14994 |
T15001 |
arg1Of |
6-diamidino-2-phenylindole,at |
R10538 |
T14994 |
T15007 |
arg1Of |
6-diamidino-2-phenylindole,were |
R10539 |
T14994 |
T15008 |
arg2Of |
6-diamidino-2-phenylindole,rinsed |
R1054 |
T1982 |
T1966 |
arg2Of |
and,as |
R10540 |
T14996 |
T14995 |
arg2Of |
DAPI,( |
R10541 |
T14997 |
T14995 |
arg3Of |
),( |
R10542 |
T15000 |
T14998 |
arg2Of |
min,for |
R10543 |
T15000 |
T14999 |
arg1Of |
min,15 |
R10544 |
T15003 |
T15001 |
arg2Of |
Finally,at |
R10545 |
T15003 |
T15002 |
arg1Of |
Finally,37°C. |
R10546 |
T15003 |
T15004 |
arg1Of |
Finally,"," |
R10547 |
T15006 |
T15004 |
arg2Of |
sections,"," |
R10548 |
T15006 |
T15005 |
arg1Of |
sections,the |
R10549 |
T15008 |
T14993 |
arg2Of |
rinsed,"," |
R1055 |
T1982 |
T1981 |
arg1Of |
and,"," |
R10550 |
T15008 |
T15007 |
arg2Of |
rinsed,were |
R10551 |
T15008 |
T15009 |
arg1Of |
rinsed,"," |
R10552 |
T15010 |
T15011 |
arg1Of |
mounted,on |
R10553 |
T15010 |
T15014 |
arg1Of |
mounted,and |
R10554 |
T15012 |
T15011 |
arg2Of |
slides,on |
R10555 |
T15014 |
T15013 |
arg1Of |
and,"," |
R10556 |
T15015 |
T15014 |
arg2Of |
cover-slipped,and |
R10557 |
T15015 |
T15016 |
arg1Of |
cover-slipped,for |
R10558 |
T15018 |
T15016 |
arg2Of |
microscopy,for |
R10559 |
T15018 |
T15017 |
arg1Of |
microscopy,fluorescence |
R1056 |
T1984 |
T1982 |
arg2Of |
cancer,and |
R10560 |
T15018 |
T15019 |
arg1Of |
microscopy,( |
R10561 |
T15021 |
T15019 |
arg2Of |
microscope,( |
R10562 |
T15021 |
T15020 |
arg1Of |
microscope,DAS |
R10563 |
T15022 |
T15019 |
arg3Of |
),( |
R1057 |
T1984 |
T1983 |
arg1Of |
cancer,lung |
R1058 |
T1984 |
T1985 |
arg1Of |
cancer,[ |
R1059 |
T1986 |
T1985 |
arg2Of |
12,[ |
R106 |
T323 |
T322 |
arg1Of |
weight,tumor |
R1060 |
T1987 |
T1985 |
arg3Of |
],[ |
R1061 |
T1989 |
T1988 |
arg1Of |
data,These |
R1062 |
T1989 |
T1990 |
arg1Of |
data,suggest |
R1063 |
T1993 |
T1992 |
arg1Of |
deficiency,the |
R1064 |
T1993 |
T1994 |
arg1Of |
deficiency,of |
R1065 |
T1993 |
T1999 |
arg1Of |
deficiency,may |
R1066 |
T1993 |
T2000 |
arg1Of |
deficiency,function |
R1067 |
T1998 |
T1994 |
arg2Of |
CCR5,of |
R1068 |
T1998 |
T1995 |
arg1Of |
CCR5,inflammatory |
R1069 |
T1998 |
T1996 |
arg1Of |
CCR5,chemokine |
R107 |
T325 |
T317 |
arg2Of |
and,showed |
R1070 |
T1998 |
T1997 |
arg1Of |
CCR5,receptor |
R1071 |
T2000 |
T1990 |
arg2Of |
function,suggest |
R1072 |
T2000 |
T1991 |
arg1Of |
function,that |
R1073 |
T2000 |
T1999 |
arg2Of |
function,may |
R1074 |
T2000 |
T2001 |
arg1Of |
function,as |
R1075 |
T2004 |
T2001 |
arg2Of |
receptor,as |
R1076 |
T2004 |
T2002 |
arg1Of |
receptor,a |
R1077 |
T2004 |
T2003 |
arg1Of |
receptor,suppressive |
R1078 |
T2004 |
T2005 |
arg1Of |
receptor,in |
R1079 |
T2007 |
T2005 |
arg2Of |
progression,in |
R108 |
T325 |
T324 |
arg1Of |
and,"," |
R1080 |
T2007 |
T2006 |
arg1Of |
progression,cancer |
R1081 |
T2011 |
T2010 |
arg1Of |
studies,more |
R1082 |
T2011 |
T2012 |
arg1Of |
studies,are |
R1083 |
T2011 |
T2013 |
arg2Of |
studies,required |
R1084 |
T2013 |
T2008 |
arg1Of |
required,However |
R1085 |
T2013 |
T2009 |
arg1Of |
required,"," |
R1086 |
T2013 |
T2012 |
arg2Of |
required,are |
R1087 |
T2015 |
T2013 |
arg3Of |
describe,required |
R1088 |
T2015 |
T2014 |
arg1Of |
describe,to |
R1089 |
T2016 |
T2015 |
arg2Of |
how,describe |
R109 |
T328 |
T325 |
arg2Of |
rate,and |
R1090 |
T2018 |
T2017 |
arg1Of |
deficiency,CCR5 |
R1091 |
T2018 |
T2019 |
arg1Of |
deficiency,acts |
R10916 |
T15453 |
T15452 |
arg1Of |
sections,the |
R10917 |
T15453 |
T15454 |
arg1Of |
sections,were |
R10918 |
T15453 |
T15455 |
arg2Of |
sections,rinsed |
R10919 |
T15453 |
T15457 |
arg2Of |
sections,mounted |
R1092 |
T2019 |
T2016 |
arg1Of |
acts,how |
R10920 |
T15453 |
T15462 |
arg1Of |
sections,cover-slipped |
R10921 |
T15455 |
T15456 |
arg1Of |
rinsed,"," |
R10922 |
T15456 |
T15461 |
arg1Of |
",",and |
R10923 |
T15457 |
T15456 |
arg2Of |
mounted,"," |
R10924 |
T15457 |
T15458 |
arg1Of |
mounted,on |
R10925 |
T15459 |
T15458 |
arg2Of |
slides,on |
R10926 |
T15461 |
T15450 |
arg1Of |
and,Finally |
R10927 |
T15461 |
T15451 |
arg1Of |
and,"," |
R10928 |
T15461 |
T15454 |
arg2Of |
and,were |
R10929 |
T15461 |
T15460 |
arg1Of |
and,"," |
R1093 |
T2019 |
T2020 |
arg1Of |
acts,in |
R10930 |
T15462 |
T15461 |
arg2Of |
cover-slipped,and |
R10931 |
T15462 |
T15463 |
arg1Of |
cover-slipped,for |
R10932 |
T15465 |
T15464 |
arg1Of |
microscopy,fluorescence |
R10933 |
T15465 |
T15466 |
arg1Of |
microscopy,and |
R10934 |
T15466 |
T15463 |
arg2Of |
and,for |
R10935 |
T15466 |
T15468 |
arg1Of |
and,using |
R10936 |
T15467 |
T15466 |
arg2Of |
photography,and |
R10937 |
T15470 |
T15468 |
arg2Of |
microscopy,using |
R10938 |
T15470 |
T15469 |
arg1Of |
microscopy,ApoTome |
R10939 |
T15470 |
T15471 |
arg1Of |
microscopy,( |
R1094 |
T2022 |
T2020 |
arg2Of |
inhibition,in |
R10940 |
T15473 |
T15472 |
arg1Of |
Zeiss,Carl |
R10941 |
T15473 |
T15474 |
arg1Of |
Zeiss,"," |
R10942 |
T15474 |
T15476 |
arg1Of |
",","," |
R10943 |
T15475 |
T15474 |
arg2Of |
Thornwood,"," |
R10944 |
T15476 |
T15471 |
arg2Of |
",",( |
R10945 |
T15476 |
T15478 |
arg1Of |
",","," |
R10946 |
T15476 |
T15479 |
arg1Of |
",",USA |
R10947 |
T15477 |
T15476 |
arg2Of |
NY,"," |
R10948 |
T15480 |
T15471 |
arg3Of |
),( |
R1095 |
T2022 |
T2021 |
arg1Of |
inhibition,the |
R1096 |
T2022 |
T2023 |
arg1Of |
inhibition,of |
R1097 |
T2025 |
T2023 |
arg2Of |
development,of |
R1098 |
T2025 |
T2024 |
arg1Of |
development,tumor |
R1099 |
T2028 |
T2026 |
arg1Of |
antagonist,Interleukin-1 |
R110 |
T328 |
T326 |
arg2Of |
rate,increased |
R1100 |
T2028 |
T2027 |
arg1Of |
antagonist,receptor |
R1101 |
T2028 |
T2029 |
arg1Of |
antagonist,( |
R1102 |
T2028 |
T2032 |
arg1Of |
antagonist,"," |
R1103 |
T2028 |
T2040 |
arg1Of |
antagonist,is |
R1104 |
T2030 |
T2029 |
arg2Of |
IL-1Ra,( |
R1105 |
T2031 |
T2029 |
arg3Of |
),( |
R1106 |
T2034 |
T2032 |
arg2Of |
member,"," |
R1107 |
T2034 |
T2033 |
arg1Of |
member,a |
R1108 |
T2034 |
T2035 |
arg1Of |
member,of |
R1109 |
T2038 |
T2035 |
arg2Of |
family,of |
R111 |
T328 |
T327 |
arg1Of |
rate,survival |
R1110 |
T2038 |
T2036 |
arg1Of |
family,the |
R1111 |
T2038 |
T2037 |
arg1Of |
family,IL-1 |
R1112 |
T2040 |
T2039 |
arg1Of |
is,"," |
R11125 |
T15700 |
T15697 |
arg1Of |
Assay,Gel |
R11126 |
T15700 |
T15698 |
arg1Of |
Assay,Electromobility |
R11127 |
T15700 |
T15699 |
arg1Of |
Assay,Shift |
R11128 |
T15705 |
T15701 |
arg1Of |
assay,A |
R11129 |
T15705 |
T15702 |
arg1Of |
assay,gel |
R1113 |
T2043 |
T2042 |
arg1Of |
occurring,naturally |
R11130 |
T15705 |
T15703 |
arg1Of |
assay,electromobility |
R11131 |
T15705 |
T15704 |
arg1Of |
assay,shift |
R11132 |
T15705 |
T15706 |
arg1Of |
assay,( |
R11133 |
T15705 |
T15709 |
arg1Of |
assay,was |
R11134 |
T15705 |
T15710 |
arg2Of |
assay,performed |
R11135 |
T15707 |
T15706 |
arg2Of |
EMSA,( |
R11136 |
T15708 |
T15706 |
arg3Of |
),( |
R11137 |
T15710 |
T15709 |
arg2Of |
performed,was |
R11138 |
T15710 |
T15711 |
arg1Of |
performed,according |
R11139 |
T15710 |
T15716 |
arg1Of |
performed,( |
R1114 |
T2044 |
T2040 |
arg2Of |
cytokine,is |
R11140 |
T15712 |
T15711 |
arg2Of |
to,according |
R11141 |
T15715 |
T15712 |
arg2Of |
recommendations,to |
R11142 |
T15715 |
T15713 |
arg1Of |
recommendations,the |
R11143 |
T15715 |
T15714 |
arg1Of |
recommendations,manufacturer’s |
R11144 |
T15717 |
T15718 |
arg1Of |
Promega,"," |
R11145 |
T15718 |
T15716 |
arg2Of |
",",( |
R11146 |
T15718 |
T15720 |
arg1Of |
",","," |
R11147 |
T15719 |
T15718 |
arg2Of |
Madison,"," |
R11148 |
T15721 |
T15720 |
arg2Of |
WI,"," |
R11149 |
T15722 |
T15716 |
arg3Of |
),( |
R1115 |
T2044 |
T2041 |
arg1Of |
cytokine,a |
R11150 |
T15725 |
T15723 |
arg1Of |
tissues,The |
R11151 |
T15725 |
T15724 |
arg1Of |
tissues,tumor |
R11152 |
T15725 |
T15726 |
arg1Of |
tissues,were |
R11153 |
T15725 |
T15728 |
arg2Of |
tissues,homogenized |
R11154 |
T15725 |
T15761 |
arg1Of |
tissues,vortexed |
R11155 |
T15725 |
T15764 |
arg1Of |
tissues,incubated |
R11156 |
T15725 |
T15773 |
arg1Of |
tissues,centrifuged |
R11157 |
T15728 |
T15726 |
arg2Of |
homogenized,were |
R11158 |
T15728 |
T15727 |
arg1Of |
homogenized,briefly |
R11159 |
T15728 |
T15729 |
arg1Of |
homogenized,in |
R1116 |
T2044 |
T2043 |
arg1Of |
cytokine,occurring |
R11160 |
T15728 |
T15760 |
arg1Of |
homogenized,"," |
R11161 |
T15731 |
T15729 |
arg2Of |
µl,in |
R11162 |
T15731 |
T15730 |
arg1Of |
µl,200 |
R11163 |
T15731 |
T15732 |
arg1Of |
µl,of |
R11164 |
T15731 |
T15735 |
arg1Of |
µl,( |
R11165 |
T15734 |
T15732 |
arg2Of |
A,of |
R11166 |
T15734 |
T15733 |
arg1Of |
A,solution |
R11167 |
T15736 |
T15737 |
arg1Of |
10,mM |
R11168 |
T15738 |
T15736 |
arg1Of |
HEPES,10 |
R11169 |
T15738 |
T15739 |
arg1Of |
HEPES,[ |
R1117 |
T2044 |
T2045 |
arg1Of |
cytokine,that |
R11170 |
T15738 |
T15743 |
arg1Of |
HEPES,"," |
R11171 |
T15740 |
T15739 |
arg2Of |
pH,[ |
R11172 |
T15740 |
T15741 |
arg1Of |
pH,7.9 |
R11173 |
T15742 |
T15739 |
arg3Of |
],[ |
R11174 |
T15743 |
T15747 |
arg1Of |
",","," |
R11175 |
T15744 |
T15745 |
arg1Of |
1.5,mM |
R11176 |
T15746 |
T15743 |
arg2Of |
MgCl2,"," |
R11177 |
T15746 |
T15744 |
arg1Of |
MgCl2,1.5 |
R11178 |
T15747 |
T15751 |
arg1Of |
",","," |
R11179 |
T15748 |
T15749 |
arg1Of |
10,mM |
R1118 |
T2044 |
T2047 |
arg1Of |
cytokine,blocks |
R11180 |
T15750 |
T15747 |
arg2Of |
KCl,"," |
R11181 |
T15750 |
T15748 |
arg1Of |
KCl,10 |
R11182 |
T15751 |
T15735 |
arg2Of |
",",( |
R11183 |
T15751 |
T15755 |
arg1Of |
",","," |
R11184 |
T15752 |
T15753 |
arg1Of |
0.5,mM |
R11185 |
T15754 |
T15751 |
arg2Of |
dithiothreitol,"," |
R11186 |
T15754 |
T15752 |
arg1Of |
dithiothreitol,0.5 |
R11187 |
T15756 |
T15757 |
arg1Of |
0.2,mM |
R11188 |
T15758 |
T15755 |
arg2Of |
phenylmethylsulfonylfluoride,"," |
R11189 |
T15758 |
T15756 |
arg1Of |
phenylmethylsulfonylfluoride,0.2 |
R1119 |
T2047 |
T2046 |
arg1Of |
blocks,competitively |
R11190 |
T15759 |
T15735 |
arg3Of |
),( |
R11191 |
T15760 |
T15763 |
arg1Of |
",","," |
R11192 |
T15761 |
T15760 |
arg2Of |
vortexed,"," |
R11193 |
T15761 |
T15762 |
arg1Of |
vortexed,vigorously |
R11194 |
T15763 |
T15771 |
arg1Of |
",",and |
R11195 |
T15764 |
T15763 |
arg2Of |
incubated,"," |
R11196 |
T15764 |
T15765 |
arg1Of |
incubated,on |
R11197 |
T15764 |
T15767 |
arg1Of |
incubated,for |
R11198 |
T15766 |
T15765 |
arg2Of |
ice,on |
R11199 |
T15769 |
T15767 |
arg2Of |
min,for |
R112 |
T330 |
T329 |
arg2Of |
compared,when |
R1120 |
T2047 |
T2051 |
arg1Of |
blocks,[ |
R11200 |
T15769 |
T15768 |
arg1Of |
min,10 |
R11201 |
T15771 |
T15770 |
arg1Of |
and,"," |
R11202 |
T15773 |
T15771 |
arg2Of |
centrifuged,and |
R11203 |
T15773 |
T15772 |
arg1Of |
centrifuged,then |
R11204 |
T15773 |
T15774 |
arg1Of |
centrifuged,at |
R11205 |
T15773 |
T15777 |
arg1Of |
centrifuged,for |
R11206 |
T15776 |
T15774 |
arg2Of |
rpm,at |
R11207 |
T15776 |
T15775 |
arg1Of |
rpm,15000 |
R11208 |
T15779 |
T15777 |
arg2Of |
min,for |
R11209 |
T15779 |
T15778 |
arg1Of |
min,15 |
R1121 |
T2050 |
T2047 |
arg2Of |
receptor,blocks |
R11210 |
T15782 |
T15780 |
arg1Of |
nuclei,The |
R11211 |
T15782 |
T15781 |
arg2Of |
nuclei,pelleted |
R11212 |
T15782 |
T15783 |
arg1Of |
nuclei,were |
R11213 |
T15782 |
T15784 |
arg2Of |
nuclei,resuspended |
R11214 |
T15782 |
T15803 |
arg2Of |
nuclei,incubated |
R11215 |
T15784 |
T15785 |
arg1Of |
resuspended,in |
R11216 |
T15784 |
T15802 |
arg1Of |
resuspended,and |
R11217 |
T15787 |
T15785 |
arg2Of |
C,in |
R11218 |
T15787 |
T15786 |
arg1Of |
C,solution |
R11219 |
T15787 |
T15788 |
arg1Of |
C,( |
R1122 |
T2050 |
T2048 |
arg1Of |
receptor,the |
R11220 |
T15790 |
T15788 |
arg2Of |
A,( |
R11221 |
T15790 |
T15789 |
arg1Of |
A,solution |
R11222 |
T15790 |
T15791 |
arg2Of |
A,supplemented |
R11223 |
T15791 |
T15792 |
arg1Of |
supplemented,with |
R11224 |
T15793 |
T15794 |
arg1Of |
420,mM |
R11225 |
T15795 |
T15793 |
arg1Of |
NaCl,420 |
R11226 |
T15795 |
T15796 |
arg1Of |
NaCl,and |
R11227 |
T15796 |
T15792 |
arg2Of |
and,with |
R11228 |
T15797 |
T15798 |
arg1Of |
20,% |
R11229 |
T15799 |
T15796 |
arg2Of |
glycerol,and |
R1123 |
T2050 |
T2049 |
arg1Of |
receptor,IL-1 |
R11230 |
T15799 |
T15797 |
arg1Of |
glycerol,20 |
R11231 |
T15800 |
T15788 |
arg3Of |
),( |
R11232 |
T15802 |
T15783 |
arg2Of |
and,were |
R11233 |
T15802 |
T15801 |
arg1Of |
and,"," |
R11234 |
T15803 |
T15802 |
arg2Of |
incubated,and |
R11235 |
T15803 |
T15804 |
arg1Of |
incubated,on |
R11236 |
T15803 |
T15806 |
arg1Of |
incubated,for |
R11237 |
T15805 |
T15804 |
arg2Of |
ice,on |
R11238 |
T15808 |
T15806 |
arg2Of |
min,for |
R11239 |
T15808 |
T15807 |
arg1Of |
min,20 |
R1124 |
T2052 |
T2051 |
arg2Of |
13,[ |
R11240 |
T15811 |
T15809 |
arg1Of |
pellet,The |
R11241 |
T15811 |
T15810 |
arg1Of |
pellet,resuspended |
R11242 |
T15811 |
T15812 |
arg1Of |
pellet,was |
R11243 |
T15811 |
T15813 |
arg2Of |
pellet,centrifuged |
R11244 |
T15813 |
T15812 |
arg2Of |
centrifuged,was |
R11245 |
T15813 |
T15814 |
arg1Of |
centrifuged,at |
R11246 |
T15813 |
T15817 |
arg1Of |
centrifuged,for |
R11247 |
T15813 |
T15821 |
arg1Of |
centrifuged,and |
R11248 |
T15816 |
T15814 |
arg2Of |
rpm,at |
R11249 |
T15816 |
T15815 |
arg1Of |
rpm,15000 |
R1125 |
T2053 |
T2051 |
arg3Of |
],[ |
R11250 |
T15819 |
T15817 |
arg2Of |
min,for |
R11251 |
T15819 |
T15818 |
arg1Of |
min,15 |
R11252 |
T15821 |
T15820 |
arg1Of |
and,"," |
R11253 |
T15826 |
T15822 |
arg1Of |
supernatant,the |
R11254 |
T15826 |
T15823 |
arg1Of |
supernatant,resulting |
R11255 |
T15826 |
T15824 |
arg1Of |
supernatant,nuclear |
R11256 |
T15826 |
T15825 |
arg1Of |
supernatant,extracts |
R11257 |
T15826 |
T15827 |
arg1Of |
supernatant,were |
R11258 |
T15826 |
T15828 |
arg2Of |
supernatant,collected |
R11259 |
T15828 |
T15821 |
arg2Of |
collected,and |
R1126 |
T2055 |
T2056 |
arg1Of |
IL-1Ra,has |
R11260 |
T15828 |
T15827 |
arg2Of |
collected,were |
R11261 |
T15828 |
T15829 |
arg1Of |
collected,in |
R11262 |
T15833 |
T15829 |
arg2Of |
tube,in |
R11263 |
T15833 |
T15830 |
arg1Of |
tube,a |
R11264 |
T15833 |
T15831 |
arg1Of |
tube,chilled |
R11265 |
T15833 |
T15832 |
arg1Of |
tube,Eppendorf |
R11266 |
T15835 |
T15834 |
arg1Of |
oligonucleotides,Consensus |
R11267 |
T15835 |
T15836 |
arg1Of |
oligonucleotides,were |
R11268 |
T15835 |
T15837 |
arg2Of |
oligonucleotides,end-labeled |
R11269 |
T15835 |
T15859 |
arg2Of |
oligonucleotides,incubated |
R1127 |
T2055 |
T2057 |
arg1Of |
IL-1Ra,been |
R11270 |
T15837 |
T15858 |
arg1Of |
end-labeled,and |
R11271 |
T15838 |
T15837 |
arg3Of |
using,end-labeled |
R11272 |
T15838 |
T15847 |
arg1Of |
using,for |
R11273 |
T15841 |
T15839 |
arg1Of |
kinase,T4 |
R11274 |
T15841 |
T15840 |
arg1Of |
kinase,polynucleotide |
R11275 |
T15841 |
T15842 |
arg1Of |
kinase,and |
R11276 |
T15842 |
T15838 |
arg2Of |
and,using |
R11277 |
T15844 |
T15843 |
arg2Of |
P32,[ |
R11278 |
T15845 |
T15843 |
arg3Of |
],[ |
R11279 |
T15846 |
T15842 |
arg2Of |
-ATP,and |
R1128 |
T2055 |
T2058 |
arg2Of |
IL-1Ra,shown |
R11280 |
T15846 |
T15843 |
arg1Of |
-ATP,[ |
R11281 |
T15849 |
T15847 |
arg2Of |
min,for |
R11282 |
T15849 |
T15848 |
arg1Of |
min,10 |
R11283 |
T15849 |
T15850 |
arg1Of |
min,at |
R11284 |
T15851 |
T15850 |
arg2Of |
37°C.,at |
R11285 |
T15851 |
T15856 |
modOf |
37°C.,were |
R11286 |
T15855 |
T15852 |
arg1Of |
reactions,The |
R11287 |
T15855 |
T15853 |
arg1Of |
reactions,gel |
R11288 |
T15855 |
T15854 |
arg1Of |
reactions,shift |
R11289 |
T15855 |
T15856 |
arg1Of |
reactions,were |
R1129 |
T2055 |
T2060 |
arg1Of |
IL-1Ra,inhibit |
R11290 |
T15855 |
T15857 |
arg2Of |
reactions,assembled |
R11291 |
T15857 |
T15856 |
arg2Of |
assembled,were |
R11292 |
T15858 |
T15836 |
arg2Of |
and,were |
R11293 |
T15859 |
T15858 |
arg2Of |
incubated,and |
R11294 |
T15859 |
T15860 |
arg1Of |
incubated,at |
R11295 |
T15862 |
T15860 |
arg2Of |
temperature,at |
R11296 |
T15862 |
T15861 |
arg1Of |
temperature,room |
R11297 |
T15866 |
T15865 |
arg1Of |
ml,1 |
R11298 |
T15866 |
T15867 |
arg1Of |
ml,of |
R11299 |
T15866 |
T15871 |
arg1Of |
ml,was |
R113 |
T330 |
T331 |
arg1Of |
compared,to |
R1130 |
T2055 |
T2064 |
arg1Of |
IL-1Ra,promoting |
R11300 |
T15866 |
T15872 |
arg2Of |
ml,added |
R11301 |
T15866 |
T15877 |
arg2Of |
ml,loaded |
R11302 |
T15870 |
T15867 |
arg2Of |
buffer,of |
R11303 |
T15870 |
T15868 |
arg1Of |
buffer,gel |
R11304 |
T15870 |
T15869 |
arg1Of |
buffer,loading |
R11305 |
T15872 |
T15873 |
arg1Of |
added,to |
R11306 |
T15872 |
T15876 |
arg1Of |
added,and |
R11307 |
T15875 |
T15873 |
arg2Of |
reaction,to |
R11308 |
T15875 |
T15874 |
arg1Of |
reaction,each |
R11309 |
T15876 |
T15863 |
arg1Of |
and,Subsequently |
R1131 |
T2055 |
T2070 |
arg1Of |
IL-1Ra,enhancing |
R11310 |
T15876 |
T15864 |
arg1Of |
and,"," |
R11311 |
T15876 |
T15871 |
arg2Of |
and,was |
R11312 |
T15877 |
T15876 |
arg2Of |
loaded,and |
R11313 |
T15877 |
T15878 |
arg1Of |
loaded,onto |
R11314 |
T15880 |
T15881 |
arg1Of |
6,% |
R11315 |
T15883 |
T15878 |
arg2Of |
gel,onto |
R11316 |
T15883 |
T15879 |
arg1Of |
gel,a |
R11317 |
T15883 |
T15880 |
arg1Of |
gel,6 |
R11318 |
T15883 |
T15882 |
arg1Of |
gel,non-denaturating |
R11319 |
T15885 |
T15884 |
arg1Of |
gel,The |
R1132 |
T2058 |
T2054 |
arg2Of |
shown,Because |
R11320 |
T15885 |
T15886 |
arg1Of |
gel,was |
R11321 |
T15885 |
T15887 |
arg2Of |
gel,subjected |
R11322 |
T15887 |
T15890 |
arg1Of |
subjected,until |
R11323 |
T15887 |
T15886 |
arg2Of |
subjected,was |
R11324 |
T15887 |
T15888 |
arg1Of |
subjected,to |
R11325 |
T15889 |
T15888 |
arg2Of |
electrophoresis,to |
R11326 |
T15892 |
T15891 |
arg1Of |
dye,the |
R11327 |
T15892 |
T15893 |
arg1Of |
dye,was |
R11328 |
T15893 |
T15890 |
arg2Of |
was,until |
R11329 |
T15894 |
T15893 |
arg2Of |
four-fifths,was |
R1133 |
T2058 |
T2056 |
arg2Of |
shown,has |
R11330 |
T15894 |
T15895 |
arg1Of |
four-fifths,of |
R11331 |
T15897 |
T15895 |
arg2Of |
way,of |
R11332 |
T15897 |
T15896 |
arg1Of |
way,the |
R11333 |
T15897 |
T15898 |
arg1Of |
way,down |
R11334 |
T15900 |
T15898 |
arg2Of |
gel,down |
R11335 |
T15900 |
T15899 |
arg1Of |
gel,the |
R11336 |
T15902 |
T15901 |
arg1Of |
gel,The |
R11337 |
T15902 |
T15903 |
arg1Of |
gel,was |
R11338 |
T15902 |
T15904 |
arg2Of |
gel,dried |
R11339 |
T15902 |
T15911 |
arg2Of |
gel,exposed |
R1134 |
T2058 |
T2057 |
arg2Of |
shown,been |
R11340 |
T15904 |
T15905 |
arg1Of |
dried,for |
R11341 |
T15904 |
T15908 |
arg1Of |
dried,at |
R11342 |
T15904 |
T15910 |
arg1Of |
dried,and |
R11343 |
T15907 |
T15905 |
arg2Of |
h,for |
R11344 |
T15907 |
T15906 |
arg1Of |
h,1 |
R11345 |
T15909 |
T15908 |
arg2Of |
80°C,at |
R11346 |
T15910 |
T15903 |
arg2Of |
and,was |
R11347 |
T15911 |
T15910 |
arg2Of |
exposed,and |
R11348 |
T15911 |
T15912 |
modOf |
exposed,to |
R11349 |
T15913 |
T15912 |
arg1Of |
film,to |
R1135 |
T2060 |
T2058 |
arg3Of |
inhibit,shown |
R11350 |
T15913 |
T15915 |
arg1Of |
film,at |
R11351 |
T15914 |
T15913 |
arg2Of |
overnight,film |
R11352 |
T15916 |
T15915 |
arg2Of |
-70°C,at |
R1136 |
T2060 |
T2059 |
arg1Of |
inhibit,to |
R1137 |
T2060 |
T2063 |
arg1Of |
inhibit,by |
R1138 |
T2060 |
T2069 |
arg1Of |
inhibit,by |
R1139 |
T2062 |
T2060 |
arg2Of |
progression,inhibit |
R114 |
T333 |
T331 |
arg2Of |
mice,to |
R1140 |
T2062 |
T2061 |
arg1Of |
progression,tumor |
R1141 |
T2063 |
T2068 |
arg1Of |
by,and |
R1142 |
T2064 |
T2063 |
arg2Of |
promoting,by |
R1143 |
T2067 |
T2064 |
arg2Of |
responses,promoting |
R1144 |
T2067 |
T2065 |
arg1Of |
responses,antitumor |
R1145 |
T2067 |
T2066 |
arg1Of |
responses,immune |
R1146 |
T2069 |
T2068 |
arg2Of |
by,and |
R1147 |
T2070 |
T2069 |
arg2Of |
enhancing,by |
R1148 |
T2072 |
T2070 |
arg2Of |
activity,enhancing |
R1149 |
T2072 |
T2071 |
arg1Of |
activity,the |
R115 |
T333 |
T332 |
arg1Of |
mice,CCR5+/+ |
R1150 |
T2072 |
T2073 |
arg1Of |
activity,of |
R1151 |
T2074 |
T2073 |
arg2Of |
chemotherapy,of |
R1152 |
T2077 |
T2076 |
arg1Of |
studies,numerous |
R1153 |
T2077 |
T2078 |
arg1Of |
studies,have |
R1154 |
T2077 |
T2079 |
arg1Of |
studies,examined |
R1155 |
T2079 |
T2054 |
arg1Of |
examined,Because |
R1156 |
T2079 |
T2075 |
arg1Of |
examined,"," |
R1157 |
T2079 |
T2078 |
arg2Of |
examined,have |
R1158 |
T2081 |
T2079 |
arg2Of |
ability,examined |
R11588 |
T16225 |
T16223 |
arg1Of |
Analysis,Flow |
R11589 |
T16225 |
T16224 |
arg1Of |
Analysis,Cytometric |
R1159 |
T2081 |
T2080 |
arg1Of |
ability,the |
R11590 |
T16226 |
T16227 |
arg1Of |
Lymphocytes,were |
R11591 |
T16226 |
T16228 |
arg2Of |
Lymphocytes,obtained |
R11592 |
T16228 |
T16227 |
arg2Of |
obtained,were |
R11593 |
T16228 |
T16229 |
arg1Of |
obtained,from |
R11594 |
T16230 |
T16231 |
arg1Of |
tumor,and |
R11595 |
T16232 |
T16231 |
arg2Of |
spleen,and |
R11596 |
T16233 |
T16229 |
arg2Of |
tissues,from |
R11597 |
T16233 |
T16230 |
arg1Of |
tissues,tumor |
R11598 |
T16233 |
T16232 |
arg1Of |
tissues,spleen |
R11599 |
T16233 |
T16234 |
arg1Of |
tissues,for |
R116 |
T334 |
T335 |
arg1Of |
We,investigated |
R1160 |
T2081 |
T2082 |
arg1Of |
ability,of |
R11600 |
T16236 |
T16234 |
arg2Of |
analysis,for |
R11601 |
T16236 |
T16235 |
arg1Of |
analysis,phenotype |
R11602 |
T16237 |
T16238 |
arg1Of |
Spleen,and |
R11603 |
T16239 |
T16238 |
arg2Of |
tumor,and |
R11604 |
T16240 |
T16237 |
arg1Of |
lymphocytes,Spleen |
R11605 |
T16240 |
T16239 |
arg1Of |
lymphocytes,tumor |
R11606 |
T16240 |
T16241 |
arg1Of |
lymphocytes,were |
R11607 |
T16240 |
T16242 |
arg2Of |
lymphocytes,isolated |
R11608 |
T16242 |
T16241 |
arg2Of |
isolated,were |
R11609 |
T16242 |
T16243 |
arg1Of |
isolated,from |
R1161 |
T2081 |
T2084 |
modOf |
ability,to |
R11610 |
T16245 |
T16246 |
arg1Of |
spleen,and |
R11611 |
T16247 |
T16246 |
arg2Of |
tumor,and |
R11612 |
T16248 |
T16243 |
arg2Of |
biopsies,from |
R11613 |
T16248 |
T16244 |
arg1Of |
biopsies,fresh |
R11614 |
T16248 |
T16245 |
arg1Of |
biopsies,spleen |
R11615 |
T16248 |
T16247 |
arg1Of |
biopsies,tumor |
R11616 |
T16248 |
T16249 |
arg2Of |
biopsies,obtained |
R11617 |
T16249 |
T16250 |
arg1Of |
obtained,from |
R11618 |
T16252 |
T16250 |
arg2Of |
mice,from |
R11619 |
T16252 |
T16251 |
arg1Of |
mice,three |
R1162 |
T2083 |
T2082 |
arg2Of |
IL-1Ra,of |
R11620 |
T16252 |
T16253 |
arg1Of |
mice,per |
R11621 |
T16254 |
T16253 |
arg2Of |
group,per |
R11622 |
T16255 |
T16256 |
arg1Of |
Spleen,and |
R11623 |
T16257 |
T16256 |
arg2Of |
tumor,and |
R11624 |
T16258 |
T16255 |
arg1Of |
biopsies,Spleen |
R11625 |
T16258 |
T16257 |
arg1Of |
biopsies,tumor |
R11626 |
T16258 |
T16259 |
arg1Of |
biopsies,were |
R11627 |
T16258 |
T16261 |
arg2Of |
biopsies,homogenized |
R11628 |
T16258 |
T16278 |
arg2Of |
biopsies,placed |
R11629 |
T16261 |
T16262 |
arg1Of |
homogenized,mechanically |
R1163 |
T2085 |
T2084 |
arg1Of |
block,to |
R11630 |
T16261 |
T16263 |
arg1Of |
homogenized,in |
R11631 |
T16261 |
T16267 |
arg1Of |
homogenized,( |
R11632 |
T16261 |
T16276 |
arg1Of |
homogenized,and |
R11633 |
T16264 |
T16263 |
arg2Of |
PBS,in |
R11634 |
T16264 |
T16265 |
arg1Of |
PBS,"," |
R11635 |
T16264 |
T16266 |
arg2Of |
PBS,filtered |
R11636 |
T16271 |
T16268 |
arg1Of |
strainer,100 |
R11637 |
T16271 |
T16269 |
arg1Of |
strainer,µm |
R11638 |
T16271 |
T16270 |
arg1Of |
strainer,cell |
R11639 |
T16271 |
T16272 |
arg1Of |
strainer,; |
R1164 |
T2087 |
T2085 |
arg2Of |
progression,block |
R11640 |
T16272 |
T16267 |
arg2Of |
;,( |
R11641 |
T16274 |
T16272 |
arg2Of |
PharMingen,; |
R11642 |
T16274 |
T16273 |
arg1Of |
PharMingen,BD |
R11643 |
T16275 |
T16267 |
arg3Of |
),( |
R11644 |
T16276 |
T16259 |
arg2Of |
and,were |
R11645 |
T16276 |
T16260 |
arg1Of |
and,briefly |
R11646 |
T16278 |
T16276 |
arg2Of |
placed,and |
R11647 |
T16278 |
T16277 |
arg1Of |
placed,then |
R11648 |
T16278 |
T16279 |
arg1Of |
placed,in |
R11649 |
T16278 |
T16289 |
modOf |
placed,to |
R1165 |
T2087 |
T2086 |
arg1Of |
progression,tumor |
R11650 |
T16281 |
T16279 |
arg2Of |
buffer,in |
R11651 |
T16281 |
T16280 |
arg1Of |
buffer,lysis |
R11652 |
T16281 |
T16282 |
arg1Of |
buffer,( |
R11653 |
T16285 |
T16282 |
arg2Of |
buffer,( |
R11654 |
T16285 |
T16283 |
arg1Of |
buffer,ACK |
R11655 |
T16285 |
T16284 |
arg1Of |
buffer,lysing |
R11656 |
T16285 |
T16286 |
arg1Of |
buffer,"," |
R11657 |
T16287 |
T16286 |
arg2Of |
LONZA,"," |
R11658 |
T16288 |
T16282 |
arg3Of |
),( |
R11659 |
T16290 |
T16289 |
arg1Of |
remove,to |
R1166 |
T2089 |
T2088 |
arg1Of |
expression,IL-1Ra |
R11660 |
T16293 |
T16290 |
arg2Of |
cells,remove |
R11661 |
T16293 |
T16291 |
arg1Of |
cells,red |
R11662 |
T16293 |
T16292 |
arg1Of |
cells,blood |
R11663 |
T16295 |
T16294 |
arg1Of |
million,One |
R11664 |
T16296 |
T16295 |
arg1Of |
splenocytes,million |
R11665 |
T16296 |
T16297 |
arg1Of |
splenocytes,were |
R11666 |
T16296 |
T16298 |
arg2Of |
splenocytes,washed |
R11667 |
T16296 |
T16312 |
arg1Of |
splenocytes,re-suspended |
R11668 |
T16298 |
T16299 |
arg1Of |
washed,once |
R11669 |
T16298 |
T16300 |
arg1Of |
washed,in |
R1167 |
T2089 |
T2090 |
arg1Of |
expression,was |
R11670 |
T16298 |
T16311 |
arg1Of |
washed,and |
R11671 |
T16301 |
T16300 |
arg2Of |
PBS,in |
R11672 |
T16301 |
T16302 |
arg1Of |
PBS,containing |
R11673 |
T16303 |
T16304 |
arg1Of |
1,% |
R11674 |
T16307 |
T16302 |
arg2Of |
albumin,containing |
R11675 |
T16307 |
T16303 |
arg1Of |
albumin,1 |
R11676 |
T16307 |
T16305 |
arg1Of |
albumin,bovine |
R11677 |
T16307 |
T16306 |
arg1Of |
albumin,serum |
R11678 |
T16307 |
T16308 |
arg1Of |
albumin,( |
R11679 |
T16309 |
T16308 |
arg2Of |
BSA,( |
R1168 |
T2089 |
T2091 |
arg2Of |
expression,reduced |
R11680 |
T16310 |
T16308 |
arg3Of |
),( |
R11681 |
T16311 |
T16297 |
arg2Of |
and,were |
R11682 |
T16312 |
T16311 |
arg2Of |
re-suspended,and |
R11683 |
T16312 |
T16313 |
arg1Of |
re-suspended,in |
R11684 |
T16315 |
T16313 |
arg2Of |
µl,in |
R11685 |
T16315 |
T16314 |
arg1Of |
µl,100 |
R11686 |
T16315 |
T16316 |
arg1Of |
µl,of |
R11687 |
T16318 |
T16316 |
arg2Of |
buffer,of |
R11688 |
T16318 |
T16317 |
arg1Of |
buffer,PBS/BSA |
R11689 |
T16322 |
T16321 |
arg1Of |
million,one |
R1169 |
T2091 |
T2090 |
arg2Of |
reduced,was |
R11690 |
T16323 |
T16322 |
arg1Of |
cells,million |
R11691 |
T16323 |
T16324 |
arg2Of |
cells,obtained |
R11692 |
T16323 |
T16328 |
arg1Of |
cells,were |
R11693 |
T16323 |
T16329 |
arg2Of |
cells,placed |
R11694 |
T16323 |
T16334 |
arg2Of |
cells,incubated |
R11695 |
T16323 |
T16354 |
arg2Of |
cells,washed |
R11696 |
T16324 |
T16325 |
arg1Of |
obtained,from |
R11697 |
T16327 |
T16325 |
arg2Of |
tissues,from |
R11698 |
T16327 |
T16326 |
arg1Of |
tissues,tumor |
R11699 |
T16329 |
T16330 |
arg1Of |
placed,in |
R117 |
T335 |
T340 |
arg1Of |
investigated,since |
R1170 |
T2091 |
T2092 |
arg1Of |
reduced,in |
R11700 |
T16329 |
T16334 |
modOf |
placed,incubated |
R11701 |
T16329 |
T16352 |
arg1Of |
placed,and |
R11702 |
T16332 |
T16330 |
arg2Of |
medium,in |
R11703 |
T16332 |
T16331 |
arg1Of |
medium,RPMI |
R11704 |
T16334 |
T16333 |
arg1Of |
incubated,"," |
R11705 |
T16334 |
T16335 |
modOf |
incubated,to |
R11706 |
T16336 |
T16335 |
arg1Of |
obtain,to |
R11707 |
T16338 |
T16336 |
arg2Of |
cell,obtain |
R11708 |
T16338 |
T16337 |
arg1Of |
cell,suspension |
R11709 |
T16338 |
T16339 |
arg1Of |
cell,for |
R1171 |
T2093 |
T2094 |
arg1Of |
prostate,[ |
R11710 |
T16340 |
T16339 |
arg2Of |
1hour,for |
R11711 |
T16340 |
T16341 |
arg1Of |
1hour,at |
R11712 |
T16340 |
T16343 |
arg1Of |
1hour,"," |
R11713 |
T16340 |
T16344 |
arg2Of |
1hour,centrifuged |
R11714 |
T16340 |
T16345 |
arg1Of |
1hour,( |
R11715 |
T16342 |
T16341 |
arg2Of |
37°C,at |
R11716 |
T16347 |
T16345 |
arg2Of |
rpm,( |
R11717 |
T16347 |
T16346 |
arg1Of |
rpm,1200 |
R11718 |
T16347 |
T16348 |
arg1Of |
rpm,"," |
R11719 |
T16350 |
T16348 |
arg2Of |
min,"," |
R1172 |
T2093 |
T2097 |
arg1Of |
prostate,"," |
R11720 |
T16350 |
T16349 |
arg1Of |
min,3 |
R11721 |
T16351 |
T16345 |
arg3Of |
),( |
R11722 |
T16352 |
T16319 |
arg1Of |
and,Meanwhile |
R11723 |
T16352 |
T16320 |
arg1Of |
and,"," |
R11724 |
T16352 |
T16328 |
arg2Of |
and,were |
R11725 |
T16354 |
T16352 |
arg2Of |
washed,and |
R11726 |
T16354 |
T16353 |
arg1Of |
washed,then |
R11727 |
T16354 |
T16355 |
arg1Of |
washed,in |
R11728 |
T16356 |
T16355 |
arg2Of |
PBS,in |
R11729 |
T16360 |
T16359 |
arg1Of |
lymphocytes,the |
R1173 |
T2095 |
T2094 |
arg2Of |
14,[ |
R11730 |
T16360 |
T16361 |
arg1Of |
lymphocytes,were |
R11731 |
T16360 |
T16362 |
arg2Of |
lymphocytes,incubated |
R11732 |
T16360 |
T16386 |
arg1Of |
lymphocytes,re-suspended |
R11733 |
T16362 |
T16363 |
arg1Of |
incubated,with |
R11734 |
T16362 |
T16385 |
arg1Of |
incubated,and |
R11735 |
T16367 |
T16363 |
arg2Of |
antibodies,with |
R11736 |
T16367 |
T16364 |
arg1Of |
antibodies,various |
R11737 |
T16367 |
T16365 |
arg2Of |
antibodies,conjugated |
R11738 |
T16367 |
T16366 |
arg1Of |
antibodies,monoclonal |
R11739 |
T16367 |
T16368 |
arg1Of |
antibodies,"," |
R1174 |
T2096 |
T2094 |
arg3Of |
],[ |
R11740 |
T16367 |
T16369 |
arg1Of |
antibodies,including |
R11741 |
T16370 |
T16371 |
arg1Of |
CD4-APC,"," |
R11742 |
T16371 |
T16373 |
arg1Of |
",",and |
R11743 |
T16372 |
T16371 |
arg2Of |
CD8-FITC,"," |
R11744 |
T16373 |
T16369 |
arg2Of |
and,including |
R11745 |
T16373 |
T16375 |
arg1Of |
and,for |
R11746 |
T16373 |
T16377 |
arg1Of |
and,at |
R11747 |
T16373 |
T16379 |
arg1Of |
and,"," |
R11748 |
T16373 |
T16380 |
arg2Of |
and,washed |
R11749 |
T16374 |
T16373 |
arg2Of |
CD19-PE,and |
R1175 |
T2097 |
T2103 |
arg1Of |
",",and |
R11750 |
T16376 |
T16375 |
arg2Of |
20min,for |
R11751 |
T16378 |
T16377 |
arg2Of |
4°C,at |
R11752 |
T16380 |
T16381 |
arg1Of |
washed,twice |
R11753 |
T16380 |
T16382 |
arg1Of |
washed,in |
R11754 |
T16383 |
T16382 |
arg2Of |
PBS,in |
R11755 |
T16385 |
T16357 |
arg1Of |
and,Next |
R11756 |
T16385 |
T16358 |
arg1Of |
and,"," |
R11757 |
T16385 |
T16361 |
arg2Of |
and,were |
R11758 |
T16385 |
T16384 |
arg1Of |
and,"," |
R11759 |
T16386 |
T16385 |
arg2Of |
re-suspended,and |
R1176 |
T2098 |
T2097 |
arg2Of |
breast,"," |
R11760 |
T16386 |
T16387 |
arg1Of |
re-suspended,in |
R11761 |
T16389 |
T16387 |
arg2Of |
µl,in |
R11762 |
T16389 |
T16388 |
arg1Of |
µl,400 |
R11763 |
T16389 |
T16390 |
arg1Of |
µl,of |
R11764 |
T16391 |
T16390 |
arg2Of |
PBS,of |
R11765 |
T16395 |
T16392 |
arg1Of |
analysis,A |
R11766 |
T16395 |
T16393 |
arg1Of |
analysis,flow |
R11767 |
T16395 |
T16394 |
arg1Of |
analysis,cytometric |
R11768 |
T16395 |
T16396 |
arg1Of |
analysis,was |
R11769 |
T16395 |
T16397 |
arg2Of |
analysis,performed |
R1177 |
T2098 |
T2099 |
arg1Of |
breast,[ |
R11770 |
T16397 |
T16396 |
arg2Of |
performed,was |
R11771 |
T16397 |
T16398 |
arg1Of |
performed,on |
R11772 |
T16397 |
T16408 |
arg1Of |
performed,and |
R11773 |
T16402 |
T16398 |
arg2Of |
cytometry,on |
R11774 |
T16402 |
T16399 |
arg1Of |
cytometry,a |
R11775 |
T16402 |
T16400 |
arg1Of |
cytometry,FACSAria |
R11776 |
T16402 |
T16401 |
arg1Of |
cytometry,flow |
R11777 |
T16402 |
T16403 |
arg1Of |
cytometry,( |
R11778 |
T16405 |
T16403 |
arg2Of |
Biosciences,( |
R11779 |
T16405 |
T16404 |
arg1Of |
Biosciences,BD |
R1178 |
T2100 |
T2099 |
arg2Of |
15,[ |
R11780 |
T16406 |
T16403 |
arg3Of |
),( |
R11781 |
T16408 |
T16407 |
arg1Of |
and,"," |
R11782 |
T16410 |
T16409 |
arg1Of |
data,the |
R11783 |
T16410 |
T16411 |
arg1Of |
data,were |
R11784 |
T16410 |
T16412 |
arg2Of |
data,analyzed |
R11785 |
T16412 |
T16408 |
arg2Of |
analyzed,and |
R11786 |
T16412 |
T16411 |
arg2Of |
analyzed,were |
R11787 |
T16413 |
T16412 |
arg3Of |
using,analyzed |
R11788 |
T16413 |
T16418 |
arg1Of |
using,( |
R11789 |
T16417 |
T16413 |
arg2Of |
software,using |
R1179 |
T2101 |
T2099 |
arg3Of |
],[ |
R11790 |
T16417 |
T16414 |
arg1Of |
software,the |
R11791 |
T16417 |
T16415 |
arg1Of |
software,WinMDI |
R11792 |
T16417 |
T16416 |
arg1Of |
software,statistical |
R11793 |
T16419 |
T16420 |
arg1Of |
Scripps,"," |
R11794 |
T16420 |
T16423 |
arg1Of |
",","," |
R11795 |
T16422 |
T16420 |
arg2Of |
Jolla,"," |
R11796 |
T16422 |
T16421 |
arg1Of |
Jolla,La |
R11797 |
T16423 |
T16418 |
arg2Of |
",",( |
R11798 |
T16423 |
T16425 |
arg1Of |
",","," |
R11799 |
T16424 |
T16423 |
arg2Of |
CA,"," |
R118 |
T337 |
T335 |
arg2Of |
activation,investigated |
R1180 |
T2103 |
T2092 |
arg2Of |
and,in |
R11800 |
T16426 |
T16425 |
arg2Of |
USA,"," |
R11801 |
T16427 |
T16418 |
arg3Of |
),( |
R11802 |
T16432 |
T16428 |
arg1Of |
parameters,Forward |
R11803 |
T16432 |
T16429 |
arg1Of |
parameters,and |
R11804 |
T16432 |
T16430 |
arg1Of |
parameters,side |
R11805 |
T16432 |
T16431 |
arg1Of |
parameters,scatter |
R11806 |
T16432 |
T16433 |
arg1Of |
parameters,were |
R11807 |
T16432 |
T16434 |
arg2Of |
parameters,used |
R11808 |
T16434 |
T16433 |
arg2Of |
used,were |
R11809 |
T16436 |
T16434 |
arg3Of |
gate,used |
R1181 |
T2103 |
T2102 |
arg1Of |
and,"," |
R11810 |
T16436 |
T16435 |
arg1Of |
gate,to |
R11811 |
T16436 |
T16437 |
arg1Of |
gate,on |
R11812 |
T16438 |
T16437 |
arg2Of |
lymphocytes,on |
R1182 |
T2105 |
T2103 |
arg2Of |
cancer,and |
R1183 |
T2105 |
T2104 |
arg1Of |
cancer,skin |
R1184 |
T2105 |
T2106 |
arg1Of |
cancer,[ |
R1185 |
T2107 |
T2106 |
arg2Of |
16,[ |
R1186 |
T2108 |
T2106 |
arg3Of |
],[ |
R1187 |
T2109 |
T2110 |
arg1Of |
It,was |
R1188 |
T2109 |
T2112 |
arg2Of |
It,reported |
R1189 |
T2112 |
T2110 |
arg2Of |
reported,was |
R119 |
T337 |
T336 |
arg1Of |
activation,the |
R1190 |
T2112 |
T2111 |
arg1Of |
reported,also |
R1191 |
T2117 |
T2114 |
arg1Of |
mice,endogenous |
R1192 |
T2117 |
T2115 |
arg1Of |
mice,IL-1Ra |
R1193 |
T2117 |
T2116 |
arg1Of |
mice,deficient |
R1194 |
T2117 |
T2118 |
arg1Of |
mice,developed |
R1195 |
T2118 |
T2112 |
arg3Of |
developed,reported |
R1196 |
T2118 |
T2113 |
arg1Of |
developed,that |
R1197 |
T2118 |
T2121 |
arg1Of |
developed,following |
R1198 |
T2120 |
T2118 |
arg2Of |
tumors,developed |
R1199 |
T2120 |
T2119 |
arg1Of |
tumors,aggressive |
R120 |
T337 |
T338 |
arg1Of |
activation,of |
R1200 |
T2122 |
T2121 |
arg2Of |
exposure,following |
R1201 |
T2122 |
T2123 |
arg1Of |
exposure,to |
R1202 |
T2124 |
T2123 |
arg2Of |
carcinogens,to |
R1203 |
T2124 |
T2125 |
arg1Of |
carcinogens,[ |
R1204 |
T2126 |
T2125 |
arg2Of |
17,[ |
R12041 |
T16735 |
T16734 |
arg1Of |
Immuno-arrays,Protein |
R12042 |
T16737 |
T16738 |
arg1Of |
tumor,and |
R12043 |
T16739 |
T16738 |
arg2Of |
spleen,and |
R12044 |
T16740 |
T16736 |
arg1Of |
tissues,The |
R12045 |
T16740 |
T16737 |
arg1Of |
tissues,tumor |
R12046 |
T16740 |
T16739 |
arg1Of |
tissues,spleen |
R12047 |
T16740 |
T16741 |
arg1Of |
tissues,were |
R12048 |
T16740 |
T16742 |
arg2Of |
tissues,excised |
R12049 |
T16740 |
T16744 |
arg2Of |
tissues,homogenized |
R1205 |
T2127 |
T2125 |
arg3Of |
],[ |
R12050 |
T16742 |
T16743 |
arg1Of |
excised,and |
R12051 |
T16743 |
T16741 |
arg2Of |
and,were |
R12052 |
T16744 |
T16743 |
arg2Of |
homogenized,and |
R12053 |
T16744 |
T16745 |
arg1Of |
homogenized,in |
R12054 |
T16744 |
T16747 |
arg1Of |
homogenized,with |
R12055 |
T16746 |
T16745 |
arg2Of |
PBS,in |
R12056 |
T16750 |
T16748 |
arg1Of |
cocktail,protease |
R12057 |
T16750 |
T16749 |
arg1Of |
cocktail,inhibitor |
R12058 |
T16750 |
T16751 |
arg1Of |
cocktail,( |
R12059 |
T16750 |
T16756 |
arg1Of |
cocktail,and |
R1206 |
T2130 |
T2131 |
arg1Of |
proliferation,of |
R12060 |
T16752 |
T16751 |
arg2Of |
Sigma-Aldrich,( |
R12061 |
T16752 |
T16753 |
arg1Of |
Sigma-Aldrich,"," |
R12062 |
T16752 |
T16754 |
arg1Of |
Sigma-Aldrich,USA |
R12063 |
T16755 |
T16751 |
arg3Of |
),( |
R12064 |
T16756 |
T16747 |
arg2Of |
and,with |
R12065 |
T16758 |
T16756 |
arg2Of |
X-100,and |
R12066 |
T16758 |
T16757 |
arg1Of |
X-100,Triton |
R12067 |
T16758 |
T16759 |
arg1Of |
X-100,( |
R12068 |
T16763 |
T16759 |
arg2Of |
%,( |
R12069 |
T16763 |
T16760 |
arg1Of |
%,final |
R1207 |
T2130 |
T2141 |
arg1Of |
proliferation,was |
R12070 |
T16763 |
T16761 |
arg1Of |
%,concentration |
R12071 |
T16763 |
T16762 |
arg1Of |
%,1 |
R12072 |
T16764 |
T16759 |
arg3Of |
),( |
R12073 |
T16766 |
T16765 |
arg1Of |
samples,The |
R12074 |
T16766 |
T16767 |
arg1Of |
samples,were |
R12075 |
T16766 |
T16768 |
arg2Of |
samples,frozen |
R12076 |
T16766 |
T16772 |
arg2Of |
samples,thawed |
R12077 |
T16766 |
T16775 |
arg2Of |
samples,centrifuged |
R12078 |
T16768 |
T16769 |
arg1Of |
frozen,at |
R12079 |
T16768 |
T16771 |
arg1Of |
frozen,"," |
R1208 |
T2130 |
T2142 |
arg2Of |
proliferation,reduced |
R12080 |
T16770 |
T16769 |
arg2Of |
−70°C,at |
R12081 |
T16771 |
T16774 |
arg1Of |
",",and |
R12082 |
T16772 |
T16771 |
arg2Of |
thawed,"," |
R12083 |
T16774 |
T16767 |
arg2Of |
and,were |
R12084 |
T16774 |
T16773 |
arg1Of |
and,"," |
R12085 |
T16775 |
T16774 |
arg2Of |
centrifuged,and |
R12086 |
T16775 |
T16776 |
arg1Of |
centrifuged,at |
R12087 |
T16775 |
T16778 |
arg1Of |
centrifuged,for |
R12088 |
T16775 |
T16781 |
modOf |
centrifuged,to |
R12089 |
T16777 |
T16776 |
arg2Of |
"10,000×g",at |
R1209 |
T2130 |
T2144 |
arg1Of |
proliferation,inhibited |
R12090 |
T16780 |
T16778 |
arg2Of |
min,for |
R12091 |
T16780 |
T16779 |
arg1Of |
min,5 |
R12092 |
T16782 |
T16781 |
arg1Of |
remove,to |
R12093 |
T16784 |
T16782 |
arg2Of |
debris,remove |
R12094 |
T16784 |
T16783 |
arg1Of |
debris,cellular |
R12095 |
T16787 |
T16785 |
arg1Of |
lysates,The |
R12096 |
T16787 |
T16786 |
arg1Of |
lysates,tissue |
R12097 |
T16787 |
T16788 |
arg1Of |
lysates,were |
R12098 |
T16788 |
T16792 |
arg1Of |
were,in |
R12099 |
T16791 |
T16788 |
arg2Of |
assay,were |
R121 |
T339 |
T338 |
arg2Of |
NF-κB,of |
R1210 |
T2134 |
T2131 |
arg2Of |
cells,of |
R12100 |
T16791 |
T16789 |
arg2Of |
assay,performed |
R12101 |
T16791 |
T16790 |
arg1Of |
assay,protein |
R12102 |
T16792 |
T16797 |
arg1Of |
in,for |
R12103 |
T16795 |
T16792 |
arg2Of |
way,in |
R12104 |
T16795 |
T16793 |
arg1Of |
way,the |
R12105 |
T16795 |
T16794 |
arg1Of |
way,same |
R12106 |
T16797 |
T16796 |
arg1Of |
for,as |
R12107 |
T16799 |
T16797 |
arg2Of |
blotting,for |
R12108 |
T16799 |
T16798 |
arg1Of |
blotting,western |
R12109 |
T16801 |
T16800 |
arg1Of |
mg,4.5 |
R1211 |
T2134 |
T2132 |
arg1Of |
cells,the |
R12110 |
T16801 |
T16802 |
arg1Of |
mg,of |
R12111 |
T16801 |
T16804 |
arg1Of |
mg,"," |
R12112 |
T16801 |
T16805 |
arg2Of |
mg,collected |
R12113 |
T16801 |
T16812 |
arg1Of |
mg,were |
R12114 |
T16801 |
T16813 |
arg2Of |
mg,used |
R12115 |
T16803 |
T16802 |
arg2Of |
proteins,of |
R12116 |
T16805 |
T16806 |
arg1Of |
collected,from |
R12117 |
T16808 |
T16806 |
arg2Of |
samples,from |
R12118 |
T16808 |
T16807 |
arg1Of |
samples,three |
R12119 |
T16808 |
T16809 |
arg1Of |
samples,per |
R1212 |
T2134 |
T2133 |
arg1Of |
cells,melanoma |
R12120 |
T16810 |
T16809 |
arg2Of |
group,per |
R12121 |
T16813 |
T16811 |
arg1Of |
used,"," |
R12122 |
T16813 |
T16812 |
arg2Of |
used,were |
R12123 |
T16813 |
T16814 |
arg1Of |
used,for |
R12124 |
T16817 |
T16814 |
arg2Of |
array,for |
R12125 |
T16817 |
T16815 |
arg1Of |
array,Mouse |
R12126 |
T16817 |
T16816 |
arg1Of |
array,cytokine |
R12127 |
T16817 |
T16818 |
arg1Of |
array,as |
R12128 |
T16820 |
T16818 |
arg2Of |
protocol,as |
R12129 |
T16820 |
T16819 |
arg1Of |
protocol,the |
R1213 |
T2134 |
T2135 |
arg1Of |
cells,that |
R12130 |
T16820 |
T16821 |
arg2Of |
protocol,provided |
R12131 |
T16823 |
T16821 |
arg1Of |
supplier,provided |
R12132 |
T16823 |
T16822 |
arg2Of |
supplier,by |
R12133 |
T16823 |
T16824 |
arg1Of |
supplier,( |
R12134 |
T16826 |
T16825 |
arg1Of |
Profiler™,Proteome |
R12135 |
T16826 |
T16827 |
arg1Of |
Profiler™,"," |
R12136 |
T16827 |
T16830 |
arg1Of |
",","," |
R12137 |
T16829 |
T16827 |
arg2Of |
ARY006,"," |
R12138 |
T16829 |
T16828 |
arg1Of |
ARY006,# |
R12139 |
T16830 |
T16824 |
arg2Of |
",",( |
R1214 |
T2134 |
T2136 |
arg1Of |
cells,were |
R12140 |
T16830 |
T16835 |
arg1Of |
",","," |
R12141 |
T16834 |
T16830 |
arg2Of |
Systems,"," |
R12142 |
T16834 |
T16831 |
arg1Of |
Systems,R |
R12143 |
T16834 |
T16832 |
arg1Of |
Systems,& |
R12144 |
T16834 |
T16833 |
arg1Of |
Systems,D |
R12145 |
T16836 |
T16835 |
arg2Of |
USA,"," |
R12146 |
T16837 |
T16824 |
arg3Of |
),( |
R1215 |
T2134 |
T2137 |
arg2Of |
cells,transduced |
R1216 |
T2137 |
T2136 |
arg2Of |
transduced,were |
R1217 |
T2137 |
T2138 |
arg1Of |
transduced,with |
R1218 |
T2140 |
T2138 |
arg2Of |
gene,with |
R1219 |
T2140 |
T2139 |
arg1Of |
gene,IL-1Ra |
R122 |
T341 |
T342 |
arg1Of |
it,is |
R1220 |
T2142 |
T2141 |
arg2Of |
reduced,was |
R1221 |
T2142 |
T2143 |
arg1Of |
reduced,and |
R1222 |
T2143 |
T2128 |
arg1Of |
and,Meanwhile |
R1223 |
T2143 |
T2129 |
arg1Of |
and,"," |
R1224 |
T2143 |
T2147 |
arg1Of |
and,[ |
R1225 |
T2144 |
T2143 |
arg2Of |
inhibited,and |
R12259 |
T16986 |
T16985 |
arg1Of |
Analysis,Statistical |
R1226 |
T2146 |
T2144 |
arg2Of |
development,inhibited |
R12260 |
T16988 |
T16987 |
arg1Of |
data,The |
R12261 |
T16988 |
T16989 |
arg1Of |
data,were |
R12262 |
T16988 |
T16990 |
arg2Of |
data,analyzed |
R12263 |
T16990 |
T16989 |
arg2Of |
analyzed,were |
R12264 |
T16991 |
T16990 |
arg3Of |
using,analyzed |
R12265 |
T16994 |
T16993 |
arg1Of |
Prism,GraphPad |
R12266 |
T16994 |
T16995 |
arg1Of |
Prism,4 |
R12267 |
T16996 |
T16991 |
arg2Of |
ver,using |
R12268 |
T16996 |
T16992 |
arg1Of |
ver,the |
R12269 |
T16996 |
T16994 |
arg1Of |
ver,Prism |
R1227 |
T2146 |
T2145 |
arg1Of |
development,melanoma |
R12270 |
T16998 |
T16997 |
arg1Of |
software,4.03 |
R12271 |
T16998 |
T16999 |
arg1Of |
software,( |
R12272 |
T17001 |
T16999 |
arg2Of |
Software,( |
R12273 |
T17001 |
T17000 |
arg1Of |
Software,GraphPad |
R12274 |
T17001 |
T17002 |
arg1Of |
Software,"," |
R12275 |
T17004 |
T17002 |
arg2Of |
Jolla,"," |
R12276 |
T17004 |
T17003 |
arg1Of |
Jolla,La |
R12277 |
T17004 |
T17005 |
arg1Of |
Jolla,"," |
R12278 |
T17006 |
T17005 |
arg2Of |
CA,"," |
R12279 |
T17007 |
T16999 |
arg3Of |
),( |
R1228 |
T2148 |
T2147 |
arg2Of |
18,[ |
R12280 |
T17008 |
T17009 |
arg1Of |
Data,are |
R12281 |
T17008 |
T17010 |
arg2Of |
Data,presented |
R12282 |
T17010 |
T17009 |
arg2Of |
presented,are |
R12283 |
T17010 |
T17011 |
arg1Of |
presented,as |
R12284 |
T17014 |
T17011 |
arg2Of |
SD,as |
R12285 |
T17014 |
T17012 |
arg1Of |
SD,mean |
R12286 |
T17014 |
T17013 |
arg1Of |
SD,± |
R12287 |
T17015 |
T17016 |
arg1Of |
Difference,between |
R12288 |
T17015 |
T17022 |
arg1Of |
Difference,were |
R12289 |
T17015 |
T17023 |
arg2Of |
Difference,compared |
R1229 |
T2149 |
T2147 |
arg3Of |
],[ |
R12290 |
T17018 |
T17017 |
arg1Of |
mice,CCR5−/− |
R12291 |
T17018 |
T17019 |
arg1Of |
mice,and |
R12292 |
T17019 |
T17016 |
arg2Of |
and,between |
R12293 |
T17021 |
T17019 |
arg2Of |
mice,and |
R12294 |
T17021 |
T17020 |
arg1Of |
mice,CCR5+/+ |
R12295 |
T17023 |
T17022 |
arg2Of |
compared,were |
R12296 |
T17023 |
T17024 |
modOf |
compared,using |
R12297 |
T17026 |
T17024 |
arg2Of |
test,using |
R12298 |
T17026 |
T17025 |
arg1Of |
test,t |
R12299 |
T17028 |
T17027 |
arg1Of |
value,A |
R123 |
T342 |
T340 |
arg2Of |
is,since |
R1230 |
T2151 |
T2150 |
arg1Of |
blockade,IL-1R |
R12300 |
T17028 |
T17029 |
arg1Of |
value,of |
R12301 |
T17028 |
T17033 |
arg1Of |
value,was |
R12302 |
T17028 |
T17034 |
arg2Of |
value,considered |
R12303 |
T17028 |
T17036 |
arg1Of |
value,be |
R12304 |
T17028 |
T17038 |
arg1Of |
value,significant |
R12305 |
T17030 |
T17029 |
arg2Of |
p,of |
R12306 |
T17030 |
T17032 |
arg1Of |
p,0.05 |
R12307 |
T17032 |
T17031 |
arg1Of |
0.05,< |
R12308 |
T17034 |
T17033 |
arg2Of |
considered,was |
R12309 |
T17036 |
T17034 |
arg3Of |
be,considered |
R1231 |
T2151 |
T2153 |
arg1Of |
blockade,reduced |
R12310 |
T17036 |
T17035 |
arg1Of |
be,to |
R12311 |
T17038 |
T17036 |
arg2Of |
significant,be |
R12312 |
T17038 |
T17037 |
arg1Of |
significant,statistically |
R12313 |
T17040 |
T17039 |
arg1Of |
data,Survival |
R12314 |
T17040 |
T17041 |
arg1Of |
data,were |
R12315 |
T17040 |
T17042 |
arg2Of |
data,presented |
R12316 |
T17040 |
T17048 |
arg2Of |
data,compared |
R12317 |
T17040 |
T17050 |
arg2Of |
data,calculated |
R12318 |
T17042 |
T17047 |
arg1Of |
presented,and |
R12319 |
T17046 |
T17042 |
arg1Of |
estimates,presented |
R1232 |
T2153 |
T2152 |
arg1Of |
reduced,also |
R12320 |
T17046 |
T17043 |
arg2Of |
estimates,by |
R12321 |
T17046 |
T17044 |
arg1Of |
estimates,Kaplan-Meier |
R12322 |
T17046 |
T17045 |
arg1Of |
estimates,survival |
R12323 |
T17047 |
T17041 |
arg2Of |
and,were |
R12324 |
T17048 |
T17049 |
arg1Of |
compared,and |
R12325 |
T17049 |
T17047 |
arg2Of |
and,and |
R12326 |
T17050 |
T17049 |
arg2Of |
calculated,and |
R12327 |
T17054 |
T17053 |
arg2Of |
Mantel-Cox,( |
R12328 |
T17055 |
T17053 |
arg3Of |
),( |
R12329 |
T17056 |
T17048 |
arg1Of |
Test,compared |
R1233 |
T2156 |
T2153 |
arg2Of |
growth,reduced |
R12330 |
T17056 |
T17050 |
arg1Of |
Test,calculated |
R12331 |
T17056 |
T17051 |
arg2Of |
Test,by |
R12332 |
T17056 |
T17052 |
arg1Of |
Test,Log-rank |
R12333 |
T17056 |
T17053 |
arg1Of |
Test,( |
R12334 |
T17056 |
T17057 |
arg1Of |
Test,in |
R12335 |
T17059 |
T17057 |
arg2Of |
Prism,in |
R12336 |
T17059 |
T17058 |
arg1Of |
Prism,GraphPad |
R1234 |
T2156 |
T2154 |
arg1Of |
growth,hepatic |
R1235 |
T2156 |
T2155 |
arg1Of |
growth,tumor |
R1236 |
T2156 |
T2157 |
arg1Of |
growth,[ |
R1237 |
T2158 |
T2157 |
arg2Of |
19,[ |
R1238 |
T2159 |
T2157 |
arg3Of |
],[ |
R1239 |
T2162 |
T2163 |
arg1Of |
it,has |
R124 |
T346 |
T342 |
arg2Of |
factor,is |
R1240 |
T2162 |
T2165 |
arg1Of |
it,been |
R1241 |
T2162 |
T2166 |
arg2Of |
it,reported |
R1242 |
T2166 |
T2160 |
arg1Of |
reported,Moreover |
R12424 |
T17257 |
T17258 |
arg1Of |
Inhibition,of |
R12425 |
T17257 |
T17261 |
arg1Of |
Inhibition,in |
R12426 |
T17260 |
T17258 |
arg2Of |
development,of |
R12427 |
T17260 |
T17259 |
arg1Of |
development,tumor |
R12428 |
T17263 |
T17261 |
arg2Of |
mice,in |
R12429 |
T17263 |
T17262 |
arg1Of |
mice,CCR5−/− |
R1243 |
T2166 |
T2161 |
arg1Of |
reported,"," |
R12430 |
T17264 |
T17265 |
arg1Of |
A–C,"," |
R12431 |
T17265 |
T17268 |
arg1Of |
",","," |
R12432 |
T17267 |
T17265 |
arg2Of |
images,"," |
R12433 |
T17267 |
T17266 |
arg1Of |
images,Tumor |
R12434 |
T17268 |
T17271 |
arg1Of |
",",and |
R12435 |
T17269 |
T17268 |
arg2Of |
volumes,"," |
R12436 |
T17271 |
T17270 |
arg1Of |
and,"," |
R12437 |
T17272 |
T17271 |
arg2Of |
weights,and |
R12438 |
T17275 |
T17273 |
arg1Of |
cells,B16 |
R12439 |
T17275 |
T17274 |
arg1Of |
cells,melanoma |
R1244 |
T2166 |
T2163 |
arg2Of |
reported,has |
R12440 |
T17275 |
T17276 |
arg1Of |
cells,( |
R12441 |
T17275 |
T17280 |
arg1Of |
cells,were |
R12442 |
T17275 |
T17281 |
arg2Of |
cells,inoculated |
R12443 |
T17278 |
T17276 |
arg2Of |
cells/mouse,( |
R12444 |
T17278 |
T17277 |
arg1Of |
cells/mouse,5×105 |
R12445 |
T17279 |
T17276 |
arg3Of |
),( |
R12446 |
T17281 |
T17280 |
arg2Of |
inoculated,were |
R12447 |
T17281 |
T17282 |
arg1Of |
inoculated,s.c. |
R12448 |
T17281 |
T17283 |
arg1Of |
inoculated,into |
R12449 |
T17285 |
T17284 |
arg1Of |
mice,CCR5+/+ |
R1245 |
T2166 |
T2164 |
arg1Of |
reported,also |
R12450 |
T17285 |
T17286 |
arg1Of |
mice,and |
R12451 |
T17286 |
T17283 |
arg2Of |
and,into |
R12452 |
T17288 |
T17286 |
arg2Of |
mice,and |
R12453 |
T17288 |
T17287 |
arg1Of |
mice,CCR5−/− |
R12454 |
T17288 |
T17289 |
arg1Of |
mice,( |
R12455 |
T17290 |
T17289 |
arg2Of |
n = 20,( |
R12456 |
T17291 |
T17289 |
arg3Of |
),( |
R12457 |
T17293 |
T17292 |
arg1Of |
volumes,Tumor |
R12458 |
T17293 |
T17294 |
arg1Of |
volumes,were |
R12459 |
T17293 |
T17295 |
arg2Of |
volumes,measured |
R1246 |
T2166 |
T2165 |
arg2Of |
reported,been |
R12460 |
T17295 |
T17294 |
arg2Of |
measured,were |
R12461 |
T17295 |
T17297 |
arg1Of |
measured,day |
R12462 |
T17295 |
T17298 |
arg1Of |
measured,and |
R12463 |
T17297 |
T17296 |
arg1Of |
day,every |
R12464 |
T17300 |
T17299 |
arg1Of |
weights,tumor |
R12465 |
T17300 |
T17301 |
arg1Of |
weights,were |
R12466 |
T17300 |
T17302 |
arg2Of |
weights,measured |
R12467 |
T17302 |
T17298 |
arg2Of |
measured,and |
R12468 |
T17302 |
T17301 |
arg2Of |
measured,were |
R12469 |
T17302 |
T17303 |
arg1Of |
measured,at |
R1247 |
T2168 |
T2169 |
arg1Of |
IL-1Ra,reduces |
R12470 |
T17305 |
T17303 |
arg2Of |
termination,at |
R12471 |
T17305 |
T17304 |
arg1Of |
termination,study |
R12472 |
T17305 |
T17306 |
arg1Of |
termination,( |
R12473 |
T17307 |
T17306 |
arg2Of |
Day,( |
R12474 |
T17307 |
T17308 |
arg1Of |
Day,31 |
R12475 |
T17309 |
T17306 |
arg3Of |
),( |
R12476 |
T17312 |
T17310 |
arg1Of |
mice,The |
R12477 |
T17312 |
T17311 |
arg1Of |
mice,CCR5−/− |
R12478 |
T17312 |
T17313 |
arg1Of |
mice,had |
R12479 |
T17313 |
T17322 |
arg1Of |
had,as |
R1248 |
T2169 |
T2166 |
arg3Of |
reduces,reported |
R12480 |
T17316 |
T17313 |
arg2Of |
reduction,had |
R12481 |
T17316 |
T17314 |
arg1Of |
reduction,a |
R12482 |
T17316 |
T17315 |
arg1Of |
reduction,significant |
R12483 |
T17316 |
T17317 |
arg1Of |
reduction,in |
R12484 |
T17319 |
T17320 |
arg1Of |
growth,and |
R12485 |
T17320 |
T17317 |
arg2Of |
and,in |
R12486 |
T17320 |
T17318 |
arg1Of |
and,tumor |
R12487 |
T17321 |
T17320 |
arg2Of |
volume,and |
R12488 |
T17323 |
T17322 |
arg2Of |
compared,as |
R12489 |
T17323 |
T17324 |
arg1Of |
compared,to |
R1249 |
T2169 |
T2167 |
arg1Of |
reduces,that |
R12490 |
T17326 |
T17324 |
arg2Of |
mice,to |
R12491 |
T17326 |
T17325 |
arg1Of |
mice,CCR5+/+ |
R12492 |
T17328 |
T17327 |
arg1Of |
results,The |
R12493 |
T17328 |
T17329 |
arg1Of |
results,are |
R12494 |
T17328 |
T17330 |
arg2Of |
results,expressed |
R12495 |
T17330 |
T17329 |
arg2Of |
expressed,are |
R12496 |
T17330 |
T17331 |
arg1Of |
expressed,as |
R12497 |
T17334 |
T17332 |
arg1Of |
SD.,mean |
R12498 |
T17334 |
T17333 |
arg1Of |
SD.,± |
R12499 |
T17334 |
T17335 |
arg1Of |
SD.,* |
R125 |
T346 |
T343 |
arg1Of |
factor,an |
R1250 |
T2169 |
T2196 |
arg1Of |
reduces,[ |
R12500 |
T17334 |
T17336 |
arg1Of |
SD.,indicates |
R12501 |
T17336 |
T17331 |
arg2Of |
indicates,as |
R12502 |
T17338 |
T17336 |
arg2Of |
difference,indicates |
R12503 |
T17338 |
T17337 |
arg1Of |
difference,significant |
R12504 |
T17338 |
T17339 |
arg1Of |
difference,from |
R12505 |
T17341 |
T17339 |
arg2Of |
mice,from |
R12506 |
T17341 |
T17340 |
arg1Of |
mice,CCR5+/+ |
R12507 |
T17341 |
T17342 |
arg1Of |
mice,( |
R12508 |
T17343 |
T17342 |
arg2Of |
P,( |
R12509 |
T17343 |
T17344 |
arg1Of |
P,< |
R1251 |
T2171 |
T2172 |
arg1Of |
development,[ |
R12510 |
T17343 |
T17345 |
arg1Of |
P,0.05 |
R12511 |
T17346 |
T17342 |
arg3Of |
),( |
R12512 |
T17347 |
T17348 |
arg1Of |
D,"," |
R12513 |
T17347 |
T17352 |
arg1Of |
D,demonstrated |
R12514 |
T17351 |
T17348 |
arg2Of |
mice,"," |
R12515 |
T17351 |
T17349 |
arg1Of |
mice,The |
R12516 |
T17351 |
T17350 |
arg1Of |
mice,CCR5−/− |
R12517 |
T17354 |
T17353 |
arg1Of |
higher,significantly |
R12518 |
T17356 |
T17352 |
arg2Of |
rates,demonstrated |
R12519 |
T17356 |
T17354 |
arg1Of |
rates,higher |
R1252 |
T2171 |
T2175 |
arg1Of |
development,"," |
R12520 |
T17356 |
T17355 |
arg1Of |
rates,survival |
R12521 |
T17356 |
T17357 |
arg1Of |
rates,compared |
R12522 |
T17358 |
T17357 |
arg2Of |
to,compared |
R12523 |
T17360 |
T17358 |
arg2Of |
mice,to |
R12524 |
T17360 |
T17359 |
arg1Of |
mice,CCR5+/+ |
R12525 |
T17360 |
T17361 |
arg1Of |
mice,( |
R12526 |
T17362 |
T17361 |
arg2Of |
by,( |
R12527 |
T17364 |
T17362 |
arg2Of |
Test,by |
R12528 |
T17364 |
T17363 |
arg1Of |
Test,Log-rank |
R12529 |
T17365 |
T17361 |
arg3Of |
),( |
R1253 |
T2173 |
T2172 |
arg2Of |
20,[ |
R12530 |
T17368 |
T17366 |
arg1Of |
sections,E. |
R12531 |
T17368 |
T17367 |
arg1Of |
sections,Tumor |
R12532 |
T17368 |
T17369 |
arg1Of |
sections,were |
R12533 |
T17368 |
T17370 |
arg2Of |
sections,analyzed |
R12534 |
T17370 |
T17369 |
arg2Of |
analyzed,were |
R12535 |
T17375 |
T17372 |
arg1Of |
stain,H |
R12536 |
T17375 |
T17373 |
arg1Of |
stain,& |
R12537 |
T17375 |
T17374 |
arg1Of |
stain,E |
R12538 |
T17375 |
T17376 |
arg1Of |
stain,and |
R12539 |
T17376 |
T17370 |
arg1Of |
and,analyzed |
R1254 |
T2174 |
T2172 |
arg3Of |
],[ |
R12540 |
T17376 |
T17371 |
arg2Of |
and,by |
R12541 |
T17377 |
T17376 |
arg2Of |
expression,and |
R12542 |
T17377 |
T17378 |
arg1Of |
expression,of |
R12543 |
T17379 |
T17378 |
arg2Of |
proliferating,of |
R12544 |
T17379 |
T17386 |
arg1Of |
proliferating,by |
R12545 |
T17382 |
T17379 |
arg2Of |
antigen,proliferating |
R12546 |
T17382 |
T17380 |
arg1Of |
antigen,cell |
R12547 |
T17382 |
T17381 |
arg1Of |
antigen,nuclear |
R12548 |
T17382 |
T17383 |
arg1Of |
antigen,( |
R12549 |
T17384 |
T17383 |
arg2Of |
PCNA,( |
R1255 |
T2177 |
T2175 |
arg2Of |
melanoma,"," |
R12550 |
T17385 |
T17383 |
arg3Of |
),( |
R12551 |
T17387 |
T17386 |
arg2Of |
immunohistochemistry,by |
R12552 |
T17388 |
T17389 |
arg1Of |
Data,are |
R12553 |
T17390 |
T17391 |
arg1Of |
means,± |
R12554 |
T17391 |
T17389 |
arg2Of |
±,are |
R12555 |
T17392 |
T17393 |
arg1Of |
S.D.,of |
R12556 |
T17392 |
T17397 |
arg1Of |
S.D.,* |
R12557 |
T17392 |
T17398 |
arg1Of |
S.D.,indicates |
R12558 |
T17396 |
T17393 |
arg2Of |
animals.,of |
R12559 |
T17396 |
T17394 |
arg1Of |
animals.,four |
R1256 |
T2177 |
T2176 |
arg1Of |
melanoma,B16 |
R12560 |
T17396 |
T17395 |
arg1Of |
animals.,experimental |
R12561 |
T17398 |
T17391 |
arg2Of |
indicates,± |
R12562 |
T17400 |
T17398 |
arg2Of |
difference,indicates |
R12563 |
T17400 |
T17399 |
arg1Of |
difference,significant |
R12564 |
T17400 |
T17401 |
arg1Of |
difference,from |
R12565 |
T17403 |
T17401 |
arg2Of |
mice,from |
R12566 |
T17403 |
T17402 |
arg1Of |
mice,CCR5+/+ |
R12567 |
T17403 |
T17404 |
arg1Of |
mice,( |
R12568 |
T17405 |
T17404 |
arg2Of |
P,( |
R12569 |
T17405 |
T17406 |
arg1Of |
P,< |
R1257 |
T2178 |
T2179 |
arg1Of |
growth,and |
R12570 |
T17405 |
T17407 |
arg1Of |
P,0.05 |
R12571 |
T17408 |
T17404 |
arg3Of |
),( |
R12572 |
T17410 |
T17409 |
arg1Of |
bar,Scale |
R12573 |
T17410 |
T17411 |
arg1Of |
bar,indicates |
R12574 |
T17413 |
T17411 |
arg2Of |
m,indicates |
R12575 |
T17413 |
T17412 |
arg1Of |
m,50 |
R1258 |
T2179 |
T2170 |
arg1Of |
and,fibrosarcoma |
R1259 |
T2179 |
T2171 |
arg1Of |
and,development |
R126 |
T346 |
T344 |
arg2Of |
factor,implicated |
R1260 |
T2179 |
T2177 |
arg1Of |
and,melanoma |
R1261 |
T2179 |
T2181 |
arg1Of |
and,[ |
R1262 |
T2179 |
T2184 |
arg1Of |
and,"," |
R1263 |
T2180 |
T2179 |
arg2Of |
metastasis,and |
R1264 |
T2182 |
T2181 |
arg2Of |
21,[ |
R1265 |
T2183 |
T2181 |
arg3Of |
],[ |
R1266 |
T2184 |
T2192 |
arg1Of |
",",and |
R1267 |
T2187 |
T2184 |
arg2Of |
growth,"," |
R1268 |
T2187 |
T2185 |
arg1Of |
growth,colon |
R1269 |
T2187 |
T2186 |
arg1Of |
growth,adenocarcinoma |
R127 |
T346 |
T345 |
arg1Of |
factor,transcription |
R1270 |
T2187 |
T2188 |
arg1Of |
growth,[ |
R1271 |
T2189 |
T2188 |
arg2Of |
22,[ |
R1272 |
T2190 |
T2188 |
arg3Of |
],[ |
R1273 |
T2192 |
T2169 |
arg2Of |
and,reduces |
R1274 |
T2192 |
T2191 |
arg1Of |
and,"," |
R1275 |
T2195 |
T2192 |
arg2Of |
development,and |
R1276 |
T2195 |
T2193 |
arg1Of |
development,skin |
R1277 |
T2195 |
T2194 |
arg1Of |
development,cancer |
R1278 |
T2197 |
T2196 |
arg2Of |
23,[ |
R12787 |
T17786 |
T17787 |
arg1Of |
Decrease,of |
R12788 |
T17786 |
T17790 |
arg1Of |
Decrease,in |
R12789 |
T17789 |
T17787 |
arg2Of |
Activity,of |
R1279 |
T2198 |
T2196 |
arg3Of |
],[ |
R12790 |
T17789 |
T17788 |
arg1Of |
Activity,NF-κB |
R12791 |
T17792 |
T17790 |
arg2Of |
Tissue,in |
R12792 |
T17792 |
T17791 |
arg1Of |
Tissue,Tumor |
R12793 |
T17792 |
T17793 |
arg1Of |
Tissue,of |
R12794 |
T17795 |
T17793 |
arg2Of |
Mice,of |
R12795 |
T17795 |
T17794 |
arg1Of |
Mice,CCR5−/− |
R12796 |
T17801 |
T17798 |
arg1Of |
activity,The |
R12797 |
T17801 |
T17799 |
arg1Of |
activity,DNA |
R12798 |
T17801 |
T17800 |
arg1Of |
activity,binding |
R12799 |
T17801 |
T17802 |
arg1Of |
activity,of |
R128 |
T346 |
T347 |
arg1Of |
factor,in |
R1280 |
T2201 |
T2199 |
arg1Of |
mice,IL-1 |
R12800 |
T17801 |
T17804 |
arg1Of |
activity,was |
R12801 |
T17801 |
T17805 |
arg2Of |
activity,determined |
R12802 |
T17803 |
T17802 |
arg2Of |
NF-κB,of |
R12803 |
T17805 |
T17796 |
arg1Of |
determined,A |
R12804 |
T17805 |
T17797 |
arg1Of |
determined,"," |
R12805 |
T17805 |
T17804 |
arg2Of |
determined,was |
R12806 |
T17805 |
T17806 |
arg1Of |
determined,in |
R12807 |
T17805 |
T17819 |
arg1Of |
determined,by |
R12808 |
T17809 |
T17806 |
arg2Of |
extracts,in |
R12809 |
T17809 |
T17807 |
arg1Of |
extracts,the |
R1281 |
T2201 |
T2200 |
arg1Of |
mice,knockout |
R12810 |
T17809 |
T17808 |
arg1Of |
extracts,nuclear |
R12811 |
T17809 |
T17810 |
arg1Of |
extracts,of |
R12812 |
T17813 |
T17812 |
arg1Of |
mice,CCR5−/− |
R12813 |
T17813 |
T17814 |
arg1Of |
mice,and |
R12814 |
T17814 |
T17810 |
arg2Of |
and,of |
R12815 |
T17814 |
T17811 |
arg1Of |
and,the |
R12816 |
T17818 |
T17814 |
arg2Of |
tissues,and |
R12817 |
T17818 |
T17815 |
arg1Of |
tissues,CCR5+/+ |
R12818 |
T17818 |
T17816 |
arg1Of |
tissues,mice |
R12819 |
T17818 |
T17817 |
arg1Of |
tissues,tumor |
R1282 |
T2201 |
T2202 |
arg2Of |
mice,injected |
R12820 |
T17820 |
T17819 |
arg2Of |
EMSA,by |
R12821 |
T17820 |
T17821 |
arg2Of |
EMSA,described |
R12822 |
T17821 |
T17822 |
arg1Of |
described,in |
R12823 |
T17823 |
T17824 |
arg1Of |
material,and |
R12824 |
T17824 |
T17822 |
arg2Of |
and,in |
R12825 |
T17825 |
T17824 |
arg2Of |
methods,and |
R12826 |
T17826 |
T17827 |
arg1Of |
B,"," |
R12827 |
T17827 |
T17831 |
arg1Of |
",",and |
R12828 |
T17828 |
T17827 |
arg2Of |
Expression,"," |
R12829 |
T17828 |
T17829 |
arg1Of |
Expression,of |
R1283 |
T2201 |
T2205 |
arg1Of |
mice,failed |
R12830 |
T17830 |
T17829 |
arg2Of |
p50,of |
R12831 |
T17831 |
T17834 |
arg1Of |
and,in |
R12832 |
T17831 |
T17841 |
arg1Of |
and,and |
R12833 |
T17833 |
T17831 |
arg2Of |
phosphorylation,and |
R12834 |
T17833 |
T17832 |
arg1Of |
phosphorylation,p65 |
R12835 |
T17836 |
T17834 |
arg2Of |
extracts,in |
R12836 |
T17836 |
T17835 |
arg1Of |
extracts,nuclear |
R12837 |
T17836 |
T17837 |
arg1Of |
extracts,( |
R12838 |
T17838 |
T17837 |
arg2Of |
NE,( |
R12839 |
T17839 |
T17837 |
arg3Of |
),( |
R1284 |
T2201 |
T2207 |
arg1Of |
mice,develop |
R12840 |
T17841 |
T17840 |
arg1Of |
and,"," |
R12841 |
T17841 |
T17849 |
arg1Of |
and,( |
R12842 |
T17841 |
T17852 |
arg2Of |
and,determined |
R12843 |
T17842 |
T17843 |
arg1Of |
IκB,and |
R12844 |
T17843 |
T17841 |
arg2Of |
and,and |
R12845 |
T17843 |
T17846 |
arg1Of |
and,in |
R12846 |
T17845 |
T17843 |
arg2Of |
phosphorylation,and |
R12847 |
T17845 |
T17844 |
arg1Of |
phosphorylation,IκB |
R12848 |
T17848 |
T17846 |
arg2Of |
cytosol,in |
R12849 |
T17848 |
T17847 |
arg1Of |
cytosol,the |
R1285 |
T2202 |
T2203 |
arg1Of |
injected,with |
R12850 |
T17850 |
T17849 |
arg2Of |
CE,( |
R12851 |
T17851 |
T17849 |
arg3Of |
),( |
R12852 |
T17855 |
T17852 |
arg1Of |
blotting,determined |
R12853 |
T17855 |
T17853 |
arg2Of |
blotting,by |
R12854 |
T17855 |
T17854 |
arg1Of |
blotting,Western |
R12855 |
T17856 |
T17857 |
arg1Of |
C,"," |
R12856 |
T17856 |
T17862 |
arg1Of |
C,confirmed |
R12857 |
T17859 |
T17857 |
arg2Of |
analysis,"," |
R12858 |
T17859 |
T17858 |
arg1Of |
analysis,Immunolfluorescence |
R12859 |
T17859 |
T17860 |
arg1Of |
analysis,of |
R1286 |
T2204 |
T2203 |
arg2Of |
melanoma,with |
R12860 |
T17861 |
T17860 |
arg2Of |
p50,of |
R12861 |
T17865 |
T17864 |
arg1Of |
intensities,the |
R12862 |
T17865 |
T17866 |
arg1Of |
intensities,of |
R12863 |
T17865 |
T17871 |
arg1Of |
intensities,were |
R12864 |
T17865 |
T17872 |
arg2Of |
intensities,decreased |
R12865 |
T17868 |
T17866 |
arg2Of |
staining,of |
R12866 |
T17868 |
T17867 |
arg1Of |
staining,nuclear |
R12867 |
T17868 |
T17869 |
arg1Of |
staining,for |
R12868 |
T17870 |
T17869 |
arg2Of |
p50,for |
R12869 |
T17872 |
T17862 |
arg2Of |
decreased,confirmed |
R1287 |
T2207 |
T2205 |
arg2Of |
develop,failed |
R12870 |
T17872 |
T17863 |
arg1Of |
decreased,that |
R12871 |
T17872 |
T17871 |
arg2Of |
decreased,were |
R12872 |
T17872 |
T17873 |
arg1Of |
decreased,in |
R12873 |
T17876 |
T17873 |
arg2Of |
tissues,in |
R12874 |
T17876 |
T17874 |
arg1Of |
tissues,the |
R12875 |
T17876 |
T17875 |
arg1Of |
tissues,tumor |
R12876 |
T17876 |
T17877 |
arg1Of |
tissues,of |
R12877 |
T17879 |
T17877 |
arg2Of |
mice,of |
R12878 |
T17879 |
T17878 |
arg1Of |
mice,CCR5−/− |
R12879 |
T17880 |
T17881 |
arg1Of |
Data,are |
R1288 |
T2207 |
T2206 |
arg1Of |
develop,to |
R12880 |
T17882 |
T17883 |
arg1Of |
means,± |
R12881 |
T17883 |
T17881 |
arg2Of |
±,are |
R12882 |
T17884 |
T17885 |
arg1Of |
S.D.,of |
R12883 |
T17884 |
T17889 |
arg1Of |
S.D.,* |
R12884 |
T17884 |
T17890 |
arg1Of |
S.D.,indicates |
R12885 |
T17888 |
T17885 |
arg2Of |
animals.,of |
R12886 |
T17888 |
T17886 |
arg1Of |
animals.,four |
R12887 |
T17888 |
T17887 |
arg1Of |
animals.,experimental |
R12888 |
T17890 |
T17883 |
arg2Of |
indicates,± |
R12889 |
T17892 |
T17890 |
arg2Of |
difference,indicates |
R1289 |
T2209 |
T2207 |
arg2Of |
tumors,develop |
R12890 |
T17892 |
T17891 |
arg1Of |
difference,significant |
R12891 |
T17892 |
T17893 |
arg1Of |
difference,from |
R12892 |
T17895 |
T17893 |
arg2Of |
mice,from |
R12893 |
T17895 |
T17894 |
arg1Of |
mice,CCR5+/+ |
R12894 |
T17895 |
T17896 |
arg1Of |
mice,( |
R12895 |
T17897 |
T17896 |
arg2Of |
p,( |
R12896 |
T17897 |
T17898 |
arg1Of |
p,< |
R12897 |
T17897 |
T17899 |
arg1Of |
p,0.05 |
R12898 |
T17900 |
T17896 |
arg3Of |
),( |
R12899 |
T17902 |
T17901 |
arg1Of |
bar,Scale |
R129 |
T349 |
T347 |
arg2Of |
regulation,in |
R1290 |
T2209 |
T2208 |
arg1Of |
tumors,solid |
R12900 |
T17902 |
T17903 |
arg1Of |
bar,indicates |
R12901 |
T17905 |
T17903 |
arg2Of |
µm,indicates |
R12902 |
T17905 |
T17904 |
arg1Of |
µm,50 |
R1291 |
T2209 |
T2210 |
arg1Of |
tumors,[ |
R1292 |
T2211 |
T2210 |
arg2Of |
24,[ |
R1293 |
T2212 |
T2210 |
arg3Of |
],[ |
R1294 |
T2213 |
T2214 |
arg1Of |
It,was |
R1295 |
T2213 |
T2216 |
arg2Of |
It,found |
R1296 |
T2216 |
T2214 |
arg2Of |
found,was |
R1297 |
T2216 |
T2215 |
arg1Of |
found,also |
R1298 |
T2218 |
T2219 |
arg1Of |
IL-1Ra,"," |
R1299 |
T2218 |
T2220 |
arg2Of |
IL-1Ra,combined |
R130 |
T349 |
T348 |
arg1Of |
regulation,the |
R1300 |
T2218 |
T2223 |
arg1Of |
IL-1Ra,and |
R1301 |
T2220 |
T2221 |
arg1Of |
combined,with |
R1302 |
T2222 |
T2221 |
arg2Of |
temozolomide,with |
R1303 |
T2223 |
T2227 |
arg1Of |
and,demonstrated |
R1304 |
T2225 |
T2223 |
arg2Of |
chemotherapy,and |
R1305 |
T2225 |
T2224 |
arg1Of |
chemotherapy,docetaxel |
R1306 |
T2227 |
T2216 |
arg3Of |
demonstrated,found |
R1307 |
T2227 |
T2217 |
arg1Of |
demonstrated,that |
R1308 |
T2227 |
T2226 |
arg1Of |
demonstrated,"," |
R13085 |
T18249 |
T18250 |
arg1Of |
Induction,of |
R13086 |
T18249 |
T18254 |
arg1Of |
Induction,in |
R13087 |
T18253 |
T18250 |
arg2Of |
Death,of |
R13088 |
T18253 |
T18251 |
arg1Of |
Death,Apoptotic |
R13089 |
T18253 |
T18252 |
arg1Of |
Death,Cell |
R1309 |
T2227 |
T2232 |
arg1Of |
demonstrated,against |
R13090 |
T18256 |
T18254 |
arg2Of |
tissues,in |
R13091 |
T18256 |
T18255 |
arg1Of |
tissues,tumor |
R13092 |
T18256 |
T18257 |
arg1Of |
tissues,of |
R13093 |
T18260 |
T18257 |
arg2Of |
mice,of |
R13094 |
T18260 |
T18258 |
arg1Of |
mice,CCR5 |
R13095 |
T18260 |
T18259 |
arg1Of |
mice,−/− |
R13096 |
T18264 |
T18261 |
arg1Of |
cells,A |
R13097 |
T18264 |
T18262 |
arg1Of |
cells,"," |
R13098 |
T18264 |
T18263 |
arg1Of |
cells,Apoptotic |
R13099 |
T18264 |
T18265 |
arg1Of |
cells,in |
R131 |
T349 |
T350 |
arg1Of |
regulation,of |
R1310 |
T2227 |
T2238 |
arg1Of |
demonstrated,[ |
R13100 |
T18264 |
T18268 |
arg1Of |
cells,were |
R13101 |
T18264 |
T18269 |
arg2Of |
cells,examined |
R13102 |
T18267 |
T18265 |
arg2Of |
sections,in |
R13103 |
T18267 |
T18266 |
arg1Of |
sections,tumor |
R13104 |
T18269 |
T18268 |
arg2Of |
examined,were |
R13105 |
T18269 |
T18273 |
arg1Of |
examined,after |
R13106 |
T18269 |
T18278 |
arg1Of |
examined,as |
R13107 |
T18272 |
T18269 |
arg1Of |
microscopy,examined |
R13108 |
T18272 |
T18270 |
arg2Of |
microscopy,by |
R13109 |
T18272 |
T18271 |
arg1Of |
microscopy,fluorescence |
R1311 |
T2229 |
T2228 |
arg1Of |
significant,more |
R13110 |
T18274 |
T18275 |
arg1Of |
DAPI,and |
R13111 |
T18276 |
T18275 |
arg2Of |
TUNEL,and |
R13112 |
T18277 |
T18273 |
arg2Of |
staining,after |
R13113 |
T18277 |
T18274 |
arg1Of |
staining,DAPI |
R13114 |
T18277 |
T18276 |
arg1Of |
staining,TUNEL |
R13115 |
T18279 |
T18278 |
arg2Of |
described,as |
R13116 |
T18279 |
T18280 |
arg1Of |
described,in |
R13117 |
T18281 |
T18282 |
arg1Of |
material,and |
R13118 |
T18282 |
T18280 |
arg2Of |
and,in |
R13119 |
T18283 |
T18282 |
arg2Of |
methods,and |
R1312 |
T2231 |
T2227 |
arg2Of |
activity,demonstrated |
R13120 |
T18286 |
T18284 |
arg1Of |
index,The |
R13121 |
T18286 |
T18285 |
arg1Of |
index,apoptotic |
R13122 |
T18286 |
T18287 |
arg1Of |
index,was |
R13123 |
T18286 |
T18288 |
arg2Of |
index,determined |
R13124 |
T18288 |
T18287 |
arg2Of |
determined,was |
R13125 |
T18288 |
T18289 |
arg1Of |
determined,as |
R13126 |
T18291 |
T18289 |
arg2Of |
number,as |
R13127 |
T18291 |
T18290 |
arg1Of |
number,the |
R13128 |
T18291 |
T18292 |
arg1Of |
number,of |
R13129 |
T18293 |
T18294 |
arg1Of |
DAPI-stained,"," |
R1313 |
T2231 |
T2229 |
arg1Of |
activity,significant |
R13130 |
T18295 |
T18294 |
arg2Of |
TUNEL-positive,"," |
R13131 |
T18296 |
T18292 |
arg2Of |
cells,of |
R13132 |
T18296 |
T18293 |
arg1Of |
cells,DAPI-stained |
R13133 |
T18296 |
T18295 |
arg1Of |
cells,TUNEL-positive |
R13134 |
T18296 |
T18297 |
arg1Of |
cells,that |
R13135 |
T18296 |
T18298 |
arg1Of |
cells,were |
R13136 |
T18296 |
T18299 |
arg2Of |
cells,counted |
R13137 |
T18299 |
T18298 |
arg2Of |
counted,were |
R13138 |
T18300 |
T18301 |
arg1Of |
Values,are |
R13139 |
T18301 |
T18311 |
arg3Of |
are,indicates |
R1314 |
T2231 |
T2230 |
arg1Of |
activity,antitumor |
R13140 |
T18305 |
T18301 |
arg2Of |
S.D.,are |
R13141 |
T18305 |
T18302 |
arg1Of |
S.D.,the |
R13142 |
T18305 |
T18303 |
arg1Of |
S.D.,mean |
R13143 |
T18305 |
T18304 |
arg1Of |
S.D.,± |
R13144 |
T18305 |
T18306 |
arg1Of |
S.D.,of |
R13145 |
T18309 |
T18306 |
arg2Of |
animals.,of |
R13146 |
T18309 |
T18307 |
arg1Of |
animals.,four |
R13147 |
T18309 |
T18308 |
arg1Of |
animals.,experimental |
R13148 |
T18310 |
T18311 |
arg1Of |
*,indicates |
R13149 |
T18311 |
T18312 |
arg1Of |
indicates,statistically |
R1315 |
T2235 |
T2232 |
arg2Of |
cells,against |
R13150 |
T18314 |
T18311 |
arg2Of |
differences,indicates |
R13151 |
T18314 |
T18313 |
arg1Of |
differences,significant |
R13152 |
T18314 |
T18315 |
arg1Of |
differences,from |
R13153 |
T18317 |
T18315 |
arg2Of |
mice,from |
R13154 |
T18317 |
T18316 |
arg1Of |
mice,CCR5+/+ |
R13155 |
T18319 |
T18318 |
arg1Of |
bar,Scale |
R13156 |
T18319 |
T18320 |
arg1Of |
bar,indicates |
R13157 |
T18322 |
T18320 |
arg2Of |
µm,indicates |
R13158 |
T18322 |
T18321 |
arg1Of |
µm,50 |
R13159 |
T18323 |
T18324 |
arg1Of |
B,and |
R1316 |
T2235 |
T2233 |
arg1Of |
cells,B16 |
R13160 |
T18324 |
T18326 |
arg1Of |
and,"," |
R13161 |
T18324 |
T18338 |
arg1Of |
and,were |
R13162 |
T18324 |
T18339 |
arg2Of |
and,detected |
R13163 |
T18325 |
T18324 |
arg2Of |
C,and |
R13164 |
T18328 |
T18326 |
arg2Of |
protein,"," |
R13165 |
T18328 |
T18327 |
arg1Of |
protein,Apoptotic |
R13166 |
T18328 |
T18329 |
arg1Of |
protein,( |
R13167 |
T18328 |
T18335 |
arg1Of |
protein,in |
R13168 |
T18331 |
T18332 |
arg1Of |
caspase-3,and |
R13169 |
T18332 |
T18329 |
arg2Of |
and,( |
R1317 |
T2235 |
T2234 |
arg1Of |
cells,melanoma |
R13170 |
T18332 |
T18330 |
arg2Of |
and,cleaved |
R13171 |
T18333 |
T18332 |
arg2Of |
Bax,and |
R13172 |
T18334 |
T18329 |
arg3Of |
),( |
R13173 |
T18337 |
T18335 |
arg2Of |
sections,in |
R13174 |
T18337 |
T18336 |
arg1Of |
sections,tumor |
R13175 |
T18339 |
T18338 |
arg2Of |
detected,were |
R13176 |
T18342 |
T18339 |
arg1Of |
assay,detected |
R13177 |
T18342 |
T18340 |
arg2Of |
assay,by |
R13178 |
T18342 |
T18341 |
arg1Of |
assay,immunofluorescence |
R13179 |
T18346 |
T18343 |
arg1Of |
number,The |
R1318 |
T2235 |
T2237 |
arg1Of |
cells,vivo |
R13180 |
T18346 |
T18344 |
arg1Of |
number,reactive |
R13181 |
T18346 |
T18345 |
arg1Of |
number,cell |
R13182 |
T18346 |
T18347 |
arg1Of |
number,was |
R13183 |
T18346 |
T18348 |
arg2Of |
number,determined |
R13184 |
T18348 |
T18347 |
arg2Of |
determined,was |
R13185 |
T18348 |
T18349 |
arg1Of |
determined,as |
R13186 |
T18351 |
T18349 |
arg2Of |
number,as |
R13187 |
T18351 |
T18350 |
arg1Of |
number,the |
R13188 |
T18351 |
T18352 |
arg1Of |
number,of |
R13189 |
T18353 |
T18354 |
arg1Of |
DAPI-stained,"," |
R1319 |
T2237 |
T2236 |
arg1Of |
vivo,in |
R13190 |
T18355 |
T18354 |
arg2Of |
Specific,"," |
R13191 |
T18356 |
T18357 |
arg1Of |
antibody,( |
R13192 |
T18359 |
T18360 |
arg1Of |
caspase-3,and |
R13193 |
T18360 |
T18357 |
arg2Of |
and,( |
R13194 |
T18360 |
T18358 |
arg2Of |
and,cleaved |
R13195 |
T18361 |
T18360 |
arg2Of |
Bax,and |
R13196 |
T18362 |
T18357 |
arg3Of |
),( |
R13197 |
T18364 |
T18352 |
arg2Of |
cells,of |
R13198 |
T18364 |
T18353 |
arg1Of |
cells,DAPI-stained |
R13199 |
T18364 |
T18355 |
arg1Of |
cells,Specific |
R132 |
T351 |
T350 |
arg2Of |
genes,of |
R1320 |
T2239 |
T2238 |
arg2Of |
25,[ |
R13200 |
T18364 |
T18356 |
arg1Of |
cells,antibody |
R13201 |
T18364 |
T18363 |
arg1Of |
cells,-positive |
R13202 |
T18364 |
T18365 |
arg1Of |
cells,that |
R13203 |
T18364 |
T18366 |
arg1Of |
cells,were |
R13204 |
T18364 |
T18367 |
arg2Of |
cells,counted |
R13205 |
T18367 |
T18366 |
arg2Of |
counted,were |
R13206 |
T18368 |
T18369 |
arg1Of |
Values,are |
R13207 |
T18369 |
T18379 |
arg3Of |
are,indicates |
R13208 |
T18373 |
T18369 |
arg2Of |
S.D.,are |
R13209 |
T18373 |
T18370 |
arg1Of |
S.D.,the |
R1321 |
T2240 |
T2238 |
arg3Of |
],[ |
R13210 |
T18373 |
T18371 |
arg1Of |
S.D.,mean |
R13211 |
T18373 |
T18372 |
arg1Of |
S.D.,± |
R13212 |
T18373 |
T18374 |
arg1Of |
S.D.,of |
R13213 |
T18377 |
T18374 |
arg2Of |
animals.,of |
R13214 |
T18377 |
T18375 |
arg1Of |
animals.,four |
R13215 |
T18377 |
T18376 |
arg1Of |
animals.,experimental |
R13216 |
T18378 |
T18379 |
arg1Of |
*,indicates |
R13217 |
T18379 |
T18380 |
arg1Of |
indicates,statistically |
R13218 |
T18382 |
T18379 |
arg2Of |
differences,indicates |
R13219 |
T18382 |
T18381 |
arg1Of |
differences,significant |
R1322 |
T2242 |
T2241 |
arg1Of |
data,These |
R13220 |
T18382 |
T18383 |
arg1Of |
differences,from |
R13221 |
T18385 |
T18383 |
arg2Of |
mice,from |
R13222 |
T18385 |
T18384 |
arg1Of |
mice,CCR5+/+ |
R13223 |
T18387 |
T18386 |
arg1Of |
bar,Scale |
R13224 |
T18387 |
T18388 |
arg1Of |
bar,indicates |
R13225 |
T18390 |
T18388 |
arg2Of |
µm,indicates |
R13226 |
T18390 |
T18389 |
arg1Of |
µm,50 |
R13227 |
T18391 |
T18392 |
arg1Of |
D,"," |
R13228 |
T18391 |
T18398 |
arg1Of |
D,was |
R13229 |
T18391 |
T18399 |
arg2Of |
D,detected |
R1323 |
T2242 |
T2243 |
arg1Of |
data,indicate |
R13230 |
T18394 |
T18392 |
arg2Of |
expression,"," |
R13231 |
T18394 |
T18393 |
arg1Of |
expression,The |
R13232 |
T18394 |
T18395 |
arg1Of |
expression,of |
R13233 |
T18397 |
T18395 |
arg2Of |
proteins,of |
R13234 |
T18397 |
T18396 |
arg1Of |
proteins,apoptotic |
R13235 |
T18399 |
T18398 |
arg2Of |
detected,was |
R13236 |
T18399 |
T18406 |
arg1Of |
detected,; |
R13237 |
T18402 |
T18399 |
arg1Of |
blotting,detected |
R13238 |
T18402 |
T18400 |
arg2Of |
blotting,by |
R13239 |
T18402 |
T18401 |
arg1Of |
blotting,Western |
R1324 |
T2245 |
T2246 |
arg1Of |
IL-1Ra,is |
R13240 |
T18402 |
T18403 |
arg1Of |
blotting,using |
R13241 |
T18405 |
T18403 |
arg2Of |
antibodies,using |
R13242 |
T18405 |
T18404 |
arg1Of |
antibodies,specific |
R13243 |
T18408 |
T18407 |
arg2Of |
caspase-3,cleaved |
R13244 |
T18408 |
T18410 |
arg2Of |
caspase-3,cleaved |
R13245 |
T18408 |
T18413 |
arg1Of |
caspase-3,cleaved |
R13246 |
T18410 |
T18409 |
arg1Of |
cleaved,"," |
R13247 |
T18411 |
T18410 |
arg3Of |
caspase-9,cleaved |
R13248 |
T18413 |
T18406 |
arg2Of |
cleaved,; |
R13249 |
T18413 |
T18412 |
arg1Of |
cleaved,"," |
R1325 |
T2245 |
T2247 |
arg1Of |
IL-1Ra,important |
R13250 |
T18414 |
T18415 |
arg1Of |
PARP,"," |
R13251 |
T18415 |
T18417 |
arg1Of |
",","," |
R13252 |
T18416 |
T18415 |
arg2Of |
Bax,"," |
R13253 |
T18417 |
T18419 |
arg1Of |
",",and |
R13254 |
T18418 |
T18417 |
arg2Of |
Bcl-2,"," |
R13255 |
T18419 |
T18413 |
arg2Of |
and,cleaved |
R13256 |
T18419 |
T18421 |
arg1Of |
and,in |
R13257 |
T18420 |
T18419 |
arg2Of |
c-IAP1,and |
R13258 |
T18424 |
T18421 |
arg2Of |
tissues,in |
R13259 |
T18424 |
T18422 |
arg1Of |
tissues,the |
R1326 |
T2246 |
T2243 |
arg2Of |
is,indicate |
R13260 |
T18424 |
T18423 |
arg1Of |
tissues,tumor |
R13261 |
T18427 |
T18425 |
arg1Of |
protein,The |
R13262 |
T18427 |
T18426 |
arg1Of |
protein,β-actin |
R13263 |
T18427 |
T18428 |
arg1Of |
protein,was |
R13264 |
T18427 |
T18429 |
arg2Of |
protein,used |
R13265 |
T18429 |
T18428 |
arg2Of |
used,was |
R13266 |
T18429 |
T18430 |
arg1Of |
used,as |
R13267 |
T18433 |
T18430 |
arg2Of |
control,as |
R13268 |
T18433 |
T18431 |
arg1Of |
control,an |
R13269 |
T18433 |
T18432 |
arg1Of |
control,internal |
R1327 |
T2246 |
T2244 |
arg1Of |
is,that |
R13270 |
T18435 |
T18434 |
arg1Of |
band,Each |
R13271 |
T18435 |
T18436 |
arg1Of |
band,is |
R13272 |
T18435 |
T18437 |
arg1Of |
band,representative |
R13273 |
T18437 |
T18436 |
arg2Of |
representative,is |
R13274 |
T18437 |
T18438 |
arg1Of |
representative,of |
R13275 |
T18442 |
T18438 |
arg2Of |
results,of |
R13276 |
T18442 |
T18439 |
arg1Of |
results,three |
R13277 |
T18442 |
T18440 |
arg1Of |
results,independent |
R13278 |
T18442 |
T18441 |
arg1Of |
results,experimental |
R13279 |
T18443 |
T18444 |
arg1Of |
Data,are |
R1328 |
T2247 |
T2246 |
arg2Of |
important,is |
R13280 |
T18445 |
T18446 |
arg1Of |
means,± |
R13281 |
T18446 |
T18444 |
arg2Of |
±,are |
R13282 |
T18447 |
T18448 |
arg1Of |
S.D.,of |
R13283 |
T18447 |
T18452 |
arg1Of |
S.D.,* |
R13284 |
T18447 |
T18453 |
arg1Of |
S.D.,indicates |
R13285 |
T18451 |
T18448 |
arg2Of |
animals.,of |
R13286 |
T18451 |
T18449 |
arg1Of |
animals.,three |
R13287 |
T18451 |
T18450 |
arg1Of |
animals.,experimental |
R13288 |
T18453 |
T18446 |
arg2Of |
indicates,± |
R13289 |
T18455 |
T18453 |
arg2Of |
difference,indicates |
R1329 |
T2247 |
T2248 |
arg1Of |
important,as |
R13290 |
T18455 |
T18454 |
arg1Of |
difference,significant |
R13291 |
T18455 |
T18456 |
arg1Of |
difference,from |
R13292 |
T18458 |
T18456 |
arg2Of |
mice,from |
R13293 |
T18458 |
T18457 |
arg1Of |
mice,CCR5+/+ |
R13294 |
T18458 |
T18459 |
arg1Of |
mice,( |
R13295 |
T18460 |
T18459 |
arg2Of |
p,( |
R13296 |
T18460 |
T18461 |
arg1Of |
p,< |
R13297 |
T18460 |
T18462 |
arg1Of |
p,0.05 |
R13298 |
T18463 |
T18459 |
arg3Of |
),( |
R133 |
T351 |
T352 |
arg1Of |
genes,involving |
R1330 |
T2253 |
T2248 |
arg2Of |
cytokine,as |
R1331 |
T2253 |
T2249 |
arg1Of |
cytokine,a |
R1332 |
T2253 |
T2250 |
arg1Of |
cytokine,tumor |
R1333 |
T2253 |
T2251 |
arg1Of |
cytokine,growth |
R1334 |
T2253 |
T2252 |
arg1Of |
cytokine,suppressing |
R1335 |
T2254 |
T2255 |
arg1Of |
NF-κB,plays |
R1336 |
T2254 |
T2277 |
arg1Of |
NF-κB,is |
R1337 |
T2254 |
T2279 |
arg2Of |
NF-κB,associated |
R1338 |
T2255 |
T2259 |
arg1Of |
plays,in |
R1339 |
T2255 |
T2276 |
arg1Of |
plays,and |
R134 |
T354 |
T353 |
arg1Of |
growth,cell |
R1340 |
T2258 |
T2255 |
arg2Of |
role,plays |
R1341 |
T2258 |
T2256 |
arg1Of |
role,a |
R1342 |
T2258 |
T2257 |
arg1Of |
role,crucial |
R1343 |
T2261 |
T2260 |
arg1Of |
suppression,the |
R1344 |
T2261 |
T2262 |
arg1Of |
suppression,of |
R1345 |
T2261 |
T2267 |
arg1Of |
suppression,as |
R1346 |
T2263 |
T2262 |
arg2Of |
apoptosis,of |
R1347 |
T2267 |
T2259 |
arg2Of |
as,in |
R1348 |
T2267 |
T2264 |
arg1Of |
as,"," |
R1349 |
T2267 |
T2265 |
arg1Of |
as,as |
R135 |
T354 |
T355 |
arg1Of |
growth,"," |
R1350 |
T2267 |
T2266 |
arg1Of |
as,well |
R1351 |
T2269 |
T2267 |
arg2Of |
induction,as |
R1352 |
T2269 |
T2268 |
arg1Of |
induction,the |
R1353 |
T2269 |
T2270 |
arg1Of |
induction,of |
R1354 |
T2272 |
T2273 |
arg1Of |
proliferation,and |
R1355 |
T2273 |
T2270 |
arg2Of |
and,of |
R13556 |
T18934 |
T18935 |
arg1Of |
Upregulation,of |
R13557 |
T18934 |
T18937 |
arg1Of |
Upregulation,in |
R13558 |
T18936 |
T18935 |
arg2Of |
IL-1Ra,of |
R13559 |
T18939 |
T18940 |
arg1Of |
Tumor,and |
R1356 |
T2273 |
T2271 |
arg1Of |
and,cell |
R13560 |
T18940 |
T18937 |
arg2Of |
and,in |
R13561 |
T18940 |
T18938 |
arg1Of |
and,the |
R13562 |
T18940 |
T18942 |
arg1Of |
and,of |
R13563 |
T18941 |
T18940 |
arg2Of |
Spleen,and |
R13564 |
T18944 |
T18942 |
arg2Of |
Mice,of |
R13565 |
T18944 |
T18943 |
arg1Of |
Mice,CCR5−/− |
R13566 |
T18948 |
T18945 |
arg1Of |
4A,A |
R13567 |
T18948 |
T18946 |
arg1Of |
4A,"," |
R13568 |
T18948 |
T18947 |
arg1Of |
4A,Figure |
R13569 |
T18948 |
T18949 |
arg1Of |
4A,indicates |
R1357 |
T2274 |
T2273 |
arg2Of |
inflammation,and |
R13570 |
T18953 |
T18950 |
arg1Of |
panel,mouse |
R13571 |
T18953 |
T18951 |
arg1Of |
panel,cytokine |
R13572 |
T18953 |
T18952 |
arg1Of |
panel,array |
R13573 |
T18953 |
T18954 |
arg1Of |
panel,coordinates |
R13574 |
T18954 |
T18949 |
arg2Of |
coordinates,indicates |
R13575 |
T18956 |
T18955 |
arg1Of |
membranes,Nitrocellulose |
R13576 |
T18956 |
T18957 |
arg1Of |
membranes,contain |
R13577 |
T18961 |
T18957 |
arg2Of |
antibodies,contain |
R13578 |
T18961 |
T18958 |
arg1Of |
antibodies,40 |
R13579 |
T18961 |
T18959 |
arg1Of |
antibodies,different |
R1358 |
T2276 |
T2275 |
arg1Of |
and,"," |
R13580 |
T18961 |
T18960 |
arg1Of |
antibodies,anti-cytokine |
R13581 |
T18961 |
T18962 |
arg2Of |
antibodies,printed |
R13582 |
T18962 |
T18963 |
arg1Of |
printed,in |
R13583 |
T18964 |
T18963 |
arg2Of |
duplicate,in |
R13584 |
T18965 |
T18966 |
arg1Of |
B,"," |
R13585 |
T18969 |
T18966 |
arg2Of |
array,"," |
R13586 |
T18969 |
T18967 |
arg1Of |
array,Mouse |
R13587 |
T18969 |
T18968 |
arg1Of |
array,cytokine |
R13588 |
T18970 |
T18965 |
arg1Of |
panel,B |
R13589 |
T18970 |
T18969 |
arg1Of |
panel,array |
R1359 |
T2279 |
T2276 |
arg2Of |
associated,and |
R13590 |
T18970 |
T18971 |
arg1Of |
panel,indicate |
R13591 |
T18975 |
T18971 |
arg2Of |
difference,indicate |
R13592 |
T18975 |
T18972 |
arg1Of |
difference,the |
R13593 |
T18975 |
T18973 |
arg1Of |
difference,cytokine |
R13594 |
T18975 |
T18974 |
arg1Of |
difference,expression |
R13595 |
T18975 |
T18976 |
arg1Of |
difference,in |
R13596 |
T18978 |
T18976 |
arg2Of |
tissues,in |
R13597 |
T18978 |
T18977 |
arg1Of |
tissues,tumor |
R13598 |
T18978 |
T18979 |
arg1Of |
tissues,of |
R13599 |
T18981 |
T18980 |
arg1Of |
mice,CCR5+/+ |
R136 |
T355 |
T358 |
arg1Of |
",",and |
R1360 |
T2279 |
T2277 |
arg2Of |
associated,is |
R13600 |
T18981 |
T18982 |
arg1Of |
mice,and |
R13601 |
T18982 |
T18979 |
arg2Of |
and,of |
R13602 |
T18982 |
T18985 |
arg1Of |
and,"," |
R13603 |
T18984 |
T18982 |
arg2Of |
mice,and |
R13604 |
T18984 |
T18983 |
arg1Of |
mice,CCR5−/− |
R13605 |
T18987 |
T18985 |
arg2Of |
IL-1Ra,"," |
R13606 |
T18987 |
T18986 |
arg1Of |
IL-1Ra,especially |
R13607 |
T18989 |
T18988 |
arg1Of |
blot,Representative |
R13608 |
T18989 |
T18990 |
arg1Of |
blot,from |
R13609 |
T18989 |
T18994 |
arg1Of |
blot,is |
R1361 |
T2279 |
T2278 |
arg1Of |
associated,closely |
R13610 |
T18989 |
T18995 |
arg2Of |
blot,shown |
R13611 |
T18993 |
T18990 |
arg2Of |
experiments,from |
R13612 |
T18993 |
T18991 |
arg1Of |
experiments,three |
R13613 |
T18993 |
T18992 |
arg1Of |
experiments,independent |
R13614 |
T18995 |
T18994 |
arg2Of |
shown,is |
R13615 |
T18997 |
T18996 |
arg1Of |
controls,Positive |
R13616 |
T18997 |
T18998 |
arg1Of |
controls,show |
R13617 |
T18998 |
T19005 |
arg1Of |
show,on |
R13618 |
T19001 |
T19000 |
arg1Of |
internal,manufacturer’s |
R13619 |
T19004 |
T18998 |
arg2Of |
samples,show |
R1362 |
T2279 |
T2280 |
arg1Of |
associated,with |
R13620 |
T19004 |
T18999 |
arg1Of |
samples,the |
R13621 |
T19004 |
T19001 |
arg1Of |
samples,internal |
R13622 |
T19004 |
T19002 |
arg1Of |
samples,positive |
R13623 |
T19004 |
T19003 |
arg1Of |
samples,control |
R13624 |
T19007 |
T19005 |
arg2Of |
membrane,on |
R13625 |
T19007 |
T19006 |
arg1Of |
membrane,the |
R13626 |
T19008 |
T19009 |
arg1Of |
C,"," |
R13627 |
T19010 |
T19009 |
arg2Of |
Protein,"," |
R13628 |
T19011 |
T19008 |
arg1Of |
immune-arrays,C |
R13629 |
T19011 |
T19010 |
arg1Of |
immune-arrays,Protein |
R1363 |
T2279 |
T2283 |
arg1Of |
associated,[ |
R13630 |
T19011 |
T19012 |
arg1Of |
immune-arrays,were |
R13631 |
T19011 |
T19013 |
arg2Of |
immune-arrays,performed |
R13632 |
T19013 |
T19012 |
arg2Of |
performed,were |
R13633 |
T19014 |
T19013 |
arg3Of |
using,performed |
R13634 |
T19014 |
T19018 |
arg1Of |
using,in |
R13635 |
T19017 |
T19014 |
arg2Of |
array,using |
R13636 |
T19017 |
T19015 |
arg1Of |
array,Mouse |
R13637 |
T19017 |
T19016 |
arg1Of |
array,cytokine |
R13638 |
T19020 |
T19018 |
arg2Of |
tissues,in |
R13639 |
T19020 |
T19019 |
arg1Of |
tissues,spleen |
R1364 |
T2282 |
T2280 |
arg2Of |
development,with |
R13640 |
T19021 |
T19022 |
arg1Of |
There,were |
R13641 |
T19023 |
T19022 |
arg2Of |
differences,were |
R13642 |
T19023 |
T19024 |
arg1Of |
differences,in |
R13643 |
T19025 |
T19024 |
arg2Of |
cytokines,in |
R13644 |
T19025 |
T19026 |
arg1Of |
cytokines,between |
R13645 |
T19025 |
T19032 |
arg1Of |
cytokines,"," |
R13646 |
T19028 |
T19027 |
arg1Of |
mice,CCR5+/+ |
R13647 |
T19028 |
T19029 |
arg1Of |
mice,and |
R13648 |
T19029 |
T19026 |
arg2Of |
and,between |
R13649 |
T19031 |
T19029 |
arg2Of |
mice,and |
R1365 |
T2282 |
T2281 |
arg1Of |
development,cancer |
R13650 |
T19031 |
T19030 |
arg1Of |
mice,CCR5−/− |
R13651 |
T19034 |
T19032 |
arg2Of |
IL-1Ra,"," |
R13652 |
T19034 |
T19033 |
arg1Of |
IL-1Ra,especially |
R13653 |
T19036 |
T19035 |
arg1Of |
blot,Representative |
R13654 |
T19036 |
T19037 |
arg1Of |
blot,from |
R13655 |
T19036 |
T19041 |
arg1Of |
blot,is |
R13656 |
T19036 |
T19042 |
arg2Of |
blot,shown |
R13657 |
T19040 |
T19037 |
arg2Of |
experiments,from |
R13658 |
T19040 |
T19038 |
arg1Of |
experiments,three |
R13659 |
T19040 |
T19039 |
arg1Of |
experiments,independent |
R1366 |
T2284 |
T2283 |
arg2Of |
26,[ |
R13660 |
T19042 |
T19041 |
arg2Of |
shown,is |
R13661 |
T19044 |
T19043 |
arg1Of |
controls,Positive |
R13662 |
T19044 |
T19045 |
arg1Of |
controls,show |
R13663 |
T19045 |
T19052 |
arg1Of |
show,on |
R13664 |
T19048 |
T19047 |
arg1Of |
internal,manufacturer’s |
R13665 |
T19051 |
T19045 |
arg2Of |
samples,show |
R13666 |
T19051 |
T19046 |
arg1Of |
samples,the |
R13667 |
T19051 |
T19048 |
arg1Of |
samples,internal |
R13668 |
T19051 |
T19049 |
arg1Of |
samples,positive |
R13669 |
T19051 |
T19050 |
arg1Of |
samples,control |
R1367 |
T2285 |
T2283 |
arg3Of |
],[ |
R13670 |
T19054 |
T19052 |
arg2Of |
membrane,on |
R13671 |
T19054 |
T19053 |
arg1Of |
membrane,the |
R13672 |
T19055 |
T19056 |
arg1Of |
D,and |
R13673 |
T19056 |
T19058 |
arg1Of |
and,"," |
R13674 |
T19056 |
T19061 |
arg1Of |
and,was |
R13675 |
T19056 |
T19062 |
arg2Of |
and,used |
R13676 |
T19057 |
T19056 |
arg2Of |
E,and |
R13677 |
T19060 |
T19058 |
arg2Of |
analysis,"," |
R13678 |
T19060 |
T19059 |
arg1Of |
analysis,Immunolfluorescence |
R13679 |
T19062 |
T19061 |
arg2Of |
used,was |
R1368 |
T2287 |
T2286 |
arg1Of |
activation,Constitutive |
R13680 |
T19064 |
T19062 |
arg3Of |
determine,used |
R13681 |
T19064 |
T19063 |
arg1Of |
determine,to |
R13682 |
T19067 |
T19064 |
arg2Of |
levels,determine |
R13683 |
T19067 |
T19065 |
arg1Of |
levels,the |
R13684 |
T19067 |
T19066 |
arg1Of |
levels,expression |
R13685 |
T19067 |
T19068 |
arg1Of |
levels,of |
R13686 |
T19067 |
T19070 |
arg1Of |
levels,in |
R13687 |
T19069 |
T19068 |
arg2Of |
IL-1Ra,of |
R13688 |
T19071 |
T19072 |
arg1Of |
tumor,and |
R13689 |
T19073 |
T19072 |
arg2Of |
spleen,and |
R1369 |
T2287 |
T2288 |
arg1Of |
activation,of |
R13690 |
T19074 |
T19070 |
arg2Of |
tissues,in |
R13691 |
T19074 |
T19071 |
arg1Of |
tissues,tumor |
R13692 |
T19074 |
T19073 |
arg1Of |
tissues,spleen |
R13693 |
T19078 |
T19075 |
arg1Of |
number,The |
R13694 |
T19078 |
T19076 |
arg1Of |
number,reactive |
R13695 |
T19078 |
T19077 |
arg1Of |
number,cell |
R13696 |
T19078 |
T19079 |
arg1Of |
number,was |
R13697 |
T19078 |
T19080 |
arg2Of |
number,determined |
R13698 |
T19080 |
T19079 |
arg2Of |
determined,was |
R13699 |
T19080 |
T19081 |
arg1Of |
determined,as |
R137 |
T356 |
T355 |
arg2Of |
apoptosis,"," |
R1370 |
T2287 |
T2290 |
arg1Of |
activation,has |
R13700 |
T19083 |
T19081 |
arg2Of |
number,as |
R13701 |
T19083 |
T19082 |
arg1Of |
number,the |
R13702 |
T19083 |
T19084 |
arg1Of |
number,of |
R13703 |
T19085 |
T19086 |
arg1Of |
DAPI-stained,"," |
R13704 |
T19088 |
T19086 |
arg2Of |
antibody-positive,"," |
R13705 |
T19088 |
T19087 |
arg1Of |
antibody-positive,IL-1Ra |
R13706 |
T19089 |
T19084 |
arg2Of |
cells,of |
R13707 |
T19089 |
T19085 |
arg1Of |
cells,DAPI-stained |
R13708 |
T19089 |
T19088 |
arg1Of |
cells,antibody-positive |
R13709 |
T19089 |
T19090 |
arg1Of |
cells,that |
R1371 |
T2287 |
T2291 |
arg1Of |
activation,been |
R13710 |
T19089 |
T19091 |
arg1Of |
cells,were |
R13711 |
T19089 |
T19092 |
arg2Of |
cells,counted |
R13712 |
T19092 |
T19091 |
arg2Of |
counted,were |
R13713 |
T19093 |
T19094 |
arg1Of |
Values,are |
R13714 |
T19094 |
T19104 |
arg3Of |
are,indicates |
R13715 |
T19098 |
T19094 |
arg2Of |
S.D.,are |
R13716 |
T19098 |
T19095 |
arg1Of |
S.D.,the |
R13717 |
T19098 |
T19096 |
arg1Of |
S.D.,mean |
R13718 |
T19098 |
T19097 |
arg1Of |
S.D.,± |
R13719 |
T19098 |
T19099 |
arg1Of |
S.D.,of |
R1372 |
T2287 |
T2292 |
arg2Of |
activation,described |
R13720 |
T19102 |
T19099 |
arg2Of |
animals.,of |
R13721 |
T19102 |
T19100 |
arg1Of |
animals.,four |
R13722 |
T19102 |
T19101 |
arg1Of |
animals.,experimental |
R13723 |
T19103 |
T19104 |
arg1Of |
*,indicates |
R13724 |
T19104 |
T19105 |
arg1Of |
indicates,statistically |
R13725 |
T19107 |
T19104 |
arg2Of |
differences,indicates |
R13726 |
T19107 |
T19106 |
arg1Of |
differences,significant |
R13727 |
T19107 |
T19108 |
arg1Of |
differences,from |
R13728 |
T19110 |
T19108 |
arg2Of |
mice,from |
R13729 |
T19110 |
T19109 |
arg1Of |
mice,CCR5+/+ |
R1373 |
T2287 |
T2312 |
arg1Of |
activation,was |
R13730 |
T19112 |
T19111 |
arg1Of |
bar,Scale |
R13731 |
T19112 |
T19113 |
arg1Of |
bar,indicates |
R13732 |
T19115 |
T19113 |
arg2Of |
µm,indicates |
R13733 |
T19115 |
T19114 |
arg1Of |
µm,50 |
R13734 |
T19116 |
T19117 |
arg1Of |
F,and |
R13735 |
T19117 |
T19119 |
arg1Of |
and,"," |
R13736 |
T19117 |
T19123 |
arg1Of |
and,was |
R13737 |
T19117 |
T19124 |
arg2Of |
and,analyzed |
R13738 |
T19118 |
T19117 |
arg2Of |
G,and |
R13739 |
T19120 |
T19119 |
arg2Of |
Expression,"," |
R1374 |
T2287 |
T2313 |
arg2Of |
activation,found |
R13740 |
T19120 |
T19121 |
arg1Of |
Expression,of |
R13741 |
T19122 |
T19121 |
arg2Of |
IL-1Ra,of |
R13742 |
T19124 |
T19123 |
arg2Of |
analyzed,was |
R13743 |
T19127 |
T19124 |
arg1Of |
blotting,analyzed |
R13744 |
T19127 |
T19125 |
arg2Of |
blotting,by |
R13745 |
T19127 |
T19126 |
arg1Of |
blotting,western |
R13746 |
T19127 |
T19128 |
arg1Of |
blotting,in |
R13747 |
T19129 |
T19130 |
arg1Of |
tumor,and |
R13748 |
T19131 |
T19130 |
arg2Of |
spleen,and |
R13749 |
T19132 |
T19128 |
arg2Of |
tissues,in |
R1375 |
T2287 |
T2315 |
arg1Of |
activation,up-regulate |
R13750 |
T19132 |
T19129 |
arg1Of |
tissues,tumor |
R13751 |
T19132 |
T19131 |
arg1Of |
tissues,spleen |
R13752 |
T19134 |
T19133 |
arg1Of |
band,Each |
R13753 |
T19134 |
T19135 |
arg1Of |
band,is |
R13754 |
T19134 |
T19136 |
arg1Of |
band,representative |
R13755 |
T19136 |
T19135 |
arg2Of |
representative,is |
R13756 |
T19136 |
T19137 |
arg1Of |
representative,of |
R13757 |
T19141 |
T19137 |
arg2Of |
results,of |
R13758 |
T19141 |
T19138 |
arg1Of |
results,three |
R13759 |
T19141 |
T19139 |
arg1Of |
results,independent |
R1376 |
T2287 |
T2320 |
arg1Of |
activation,regulate |
R13760 |
T19141 |
T19140 |
arg1Of |
results,experimental |
R13761 |
T19142 |
T19143 |
arg1Of |
Data,are |
R13762 |
T19144 |
T19145 |
arg1Of |
means,± |
R13763 |
T19145 |
T19143 |
arg2Of |
±,are |
R13764 |
T19146 |
T19147 |
arg1Of |
S.D.,of |
R13765 |
T19146 |
T19151 |
arg1Of |
S.D.,* |
R13766 |
T19146 |
T19152 |
arg1Of |
S.D.,indicates |
R13767 |
T19150 |
T19147 |
arg2Of |
animals.,of |
R13768 |
T19150 |
T19148 |
arg1Of |
animals.,three |
R13769 |
T19150 |
T19149 |
arg1Of |
animals.,experimental |
R1377 |
T2289 |
T2288 |
arg2Of |
NF-κB,of |
R13770 |
T19152 |
T19145 |
arg2Of |
indicates,± |
R13771 |
T19154 |
T19152 |
arg2Of |
difference,indicates |
R13772 |
T19154 |
T19153 |
arg1Of |
difference,significant |
R13773 |
T19154 |
T19155 |
arg1Of |
difference,from |
R13774 |
T19157 |
T19155 |
arg2Of |
mice,from |
R13775 |
T19157 |
T19156 |
arg1Of |
mice,CCR5+/+ |
R13776 |
T19157 |
T19158 |
arg1Of |
mice,( |
R13777 |
T19159 |
T19158 |
arg2Of |
p,( |
R13778 |
T19159 |
T19160 |
arg1Of |
p,< |
R13779 |
T19159 |
T19161 |
arg1Of |
p,0.05 |
R1378 |
T2292 |
T2290 |
arg2Of |
described,has |
R13780 |
T19162 |
T19158 |
arg3Of |
),( |
R1379 |
T2292 |
T2291 |
arg2Of |
described,been |
R138 |
T358 |
T352 |
arg2Of |
and,involving |
R1380 |
T2292 |
T2293 |
arg1Of |
described,in |
R1381 |
T2292 |
T2311 |
arg1Of |
described,and |
R1382 |
T2296 |
T2293 |
arg2Of |
number,in |
R1383 |
T2296 |
T2294 |
arg1Of |
number,a |
R1384 |
T2296 |
T2295 |
arg1Of |
number,great |
R1385 |
T2296 |
T2297 |
arg1Of |
number,of |
R1386 |
T2298 |
T2297 |
arg2Of |
cancers,of |
R1387 |
T2298 |
T2299 |
arg1Of |
cancers,including |
R1388 |
T2301 |
T2300 |
arg1Of |
cancers,colon |
R1389 |
T2301 |
T2302 |
arg1Of |
cancers,"," |
R139 |
T358 |
T357 |
arg1Of |
and,"," |
R1390 |
T2302 |
T2305 |
arg1Of |
",",and |
R1391 |
T2304 |
T2302 |
arg2Of |
cancers,"," |
R1392 |
T2304 |
T2303 |
arg1Of |
cancers,prostate |
R1393 |
T2305 |
T2299 |
arg2Of |
and,including |
R1394 |
T2306 |
T2305 |
arg2Of |
melanoma,and |
R1395 |
T2306 |
T2307 |
arg1Of |
melanoma,[ |
R1396 |
T2308 |
T2307 |
arg2Of |
27,[ |
R1397 |
T2309 |
T2307 |
arg3Of |
],[ |
R1398 |
T2311 |
T2310 |
arg1Of |
and,"," |
R1399 |
T2311 |
T2324 |
arg1Of |
and,[ |
R140 |
T360 |
T358 |
arg2Of |
growth,and |
R1400 |
T2313 |
T2312 |
arg2Of |
found,was |
R1401 |
T2323 |
T2320 |
arg2Of |
expression,regulate |
R1402 |
T2323 |
T2321 |
arg1Of |
expression,apoptotic |
R1403 |
T2323 |
T2322 |
arg1Of |
expression,gene |
R1404 |
T2313 |
T2318 |
arg1Of |
found,and/or |
R1405 |
T2315 |
T2313 |
arg3Of |
up-regulate,found |
R1406 |
T2325 |
T2324 |
arg2Of |
28,[ |
R1407 |
T2326 |
T2324 |
arg3Of |
],[ |
R14072 |
T19603 |
T19604 |
arg1Of |
Induction,of |
R14073 |
T19603 |
T19614 |
arg1Of |
Induction,into |
R14074 |
T19606 |
T19604 |
arg2Of |
infiltration,of |
R14075 |
T19606 |
T19605 |
arg1Of |
infiltration,the |
R14076 |
T19606 |
T19607 |
arg1Of |
infiltration,of |
R14077 |
T19610 |
T19608 |
arg1Of |
cells,CD8+ |
R14078 |
T19610 |
T19609 |
arg1Of |
cells,T |
R14079 |
T19610 |
T19611 |
arg1Of |
cells,and |
R1408 |
T2328 |
T2329 |
arg1Of |
NF-κB,promotes |
R14080 |
T19611 |
T19607 |
arg2Of |
and,of |
R14081 |
T19613 |
T19611 |
arg2Of |
cells,and |
R14082 |
T19613 |
T19612 |
arg1Of |
cells,NK |
R14083 |
T19615 |
T19617 |
arg1Of |
tumor,and |
R14084 |
T19617 |
T19614 |
arg2Of |
and,into |
R14085 |
T19617 |
T19616 |
arg1Of |
and,"," |
R14086 |
T19618 |
T19617 |
arg2Of |
increase,and |
R14087 |
T19618 |
T19619 |
arg1Of |
increase,in |
R14088 |
T19620 |
T19619 |
arg2Of |
spleen,in |
R14089 |
T19620 |
T19621 |
arg1Of |
spleen,of |
R1409 |
T2315 |
T2314 |
arg1Of |
up-regulate,to |
R14090 |
T19623 |
T19621 |
arg2Of |
mice,of |
R14091 |
T19623 |
T19622 |
arg1Of |
mice,CCR5−/− |
R14092 |
T19626 |
T19627 |
arg1Of |
B,"," |
R14093 |
T19627 |
T19625 |
arg1Of |
",",and |
R14094 |
T19628 |
T19627 |
arg2Of |
Immunolfluorescence,"," |
R14095 |
T19629 |
T19624 |
arg1Of |
analysis,A |
R14096 |
T19629 |
T19626 |
arg1Of |
analysis,B |
R14097 |
T19629 |
T19628 |
arg1Of |
analysis,Immunolfluorescence |
R14098 |
T19629 |
T19630 |
arg1Of |
analysis,was |
R14099 |
T19629 |
T19631 |
arg2Of |
analysis,used |
R141 |
T360 |
T359 |
arg1Of |
growth,tumor |
R1410 |
T2329 |
T2327 |
arg2Of |
promotes,Although |
R14100 |
T19631 |
T19630 |
arg2Of |
used,was |
R14101 |
T19631 |
T19632 |
modOf |
used,to |
R14102 |
T19633 |
T19632 |
arg1Of |
determine,to |
R14103 |
T19636 |
T19633 |
arg2Of |
levels,determine |
R14104 |
T19636 |
T19634 |
arg1Of |
levels,the |
R14105 |
T19636 |
T19635 |
arg1Of |
levels,expression |
R14106 |
T19636 |
T19637 |
arg1Of |
levels,of |
R14107 |
T19636 |
T19653 |
arg1Of |
levels,in |
R14108 |
T19638 |
T19639 |
arg1Of |
CD8,( |
R14109 |
T19638 |
T19646 |
arg1Of |
CD8,and |
R1411 |
T2317 |
T2315 |
arg2Of |
genes,up-regulate |
R14110 |
T19644 |
T19639 |
arg2Of |
marker,( |
R14111 |
T19644 |
T19640 |
arg1Of |
marker,CD8+ |
R14112 |
T19644 |
T19641 |
arg1Of |
marker,cytotoxic |
R14113 |
T19644 |
T19642 |
arg1Of |
marker,T-cell |
R14114 |
T19644 |
T19643 |
arg1Of |
marker,surface |
R14115 |
T19645 |
T19639 |
arg3Of |
),( |
R14116 |
T19646 |
T19637 |
arg2Of |
and,of |
R14117 |
T19647 |
T19646 |
arg2Of |
CD57,and |
R14118 |
T19647 |
T19648 |
arg1Of |
CD57,( |
R14119 |
T19651 |
T19648 |
arg2Of |
marker,( |
R1412 |
T2331 |
T2329 |
arg2Of |
growth,promotes |
R14120 |
T19651 |
T19649 |
arg1Of |
marker,NK |
R14121 |
T19651 |
T19650 |
arg1Of |
marker,cell |
R14122 |
T19652 |
T19648 |
arg3Of |
),( |
R14123 |
T19654 |
T19655 |
arg1Of |
tumor,and |
R14124 |
T19656 |
T19655 |
arg2Of |
spleen,and |
R14125 |
T19657 |
T19653 |
arg2Of |
sections,in |
R14126 |
T19657 |
T19654 |
arg1Of |
sections,tumor |
R14127 |
T19657 |
T19656 |
arg1Of |
sections,spleen |
R14128 |
T19659 |
T19658 |
arg1Of |
images,The |
R14129 |
T19659 |
T19660 |
arg2Of |
images,shown |
R1413 |
T2331 |
T2330 |
arg1Of |
growth,tumor |
R14130 |
T19659 |
T19661 |
arg1Of |
images,are |
R14131 |
T19659 |
T19662 |
arg1Of |
images,representative |
R14132 |
T19662 |
T19661 |
arg2Of |
representative,are |
R14133 |
T19662 |
T19663 |
arg1Of |
representative,of |
R14134 |
T19666 |
T19663 |
arg2Of |
experiments,of |
R14135 |
T19666 |
T19664 |
arg1Of |
experiments,three |
R14136 |
T19666 |
T19665 |
arg1Of |
experiments,separate |
R14137 |
T19666 |
T19667 |
arg2Of |
experiments,performed |
R14138 |
T19667 |
T19668 |
arg1Of |
performed,in |
R14139 |
T19669 |
T19668 |
arg2Of |
triplicate,in |
R1414 |
T2333 |
T2334 |
arg1Of |
it,is |
R14140 |
T19671 |
T19670 |
arg1Of |
bars,Scale |
R14141 |
T19671 |
T19672 |
arg1Of |
bars,indicate |
R14142 |
T19674 |
T19673 |
arg1Of |
µm,50 |
R14143 |
T19674 |
T19675 |
arg1Of |
µm,( |
R14144 |
T19674 |
T19678 |
arg1Of |
µm,and |
R14145 |
T19676 |
T19675 |
arg2Of |
A,( |
R14146 |
T19677 |
T19675 |
arg3Of |
),( |
R14147 |
T19678 |
T19672 |
arg2Of |
and,indicate |
R14148 |
T19680 |
T19678 |
arg2Of |
µm,and |
R14149 |
T19680 |
T19679 |
arg1Of |
µm,100 |
R1415 |
T2333 |
T2335 |
arg2Of |
it,required |
R14150 |
T19680 |
T19681 |
arg1Of |
µm,( |
R14151 |
T19682 |
T19681 |
arg2Of |
B,( |
R14152 |
T19683 |
T19681 |
arg3Of |
),( |
R14153 |
T19684 |
T19685 |
arg1Of |
C,and |
R14154 |
T19685 |
T19687 |
arg1Of |
and,"," |
R14155 |
T19686 |
T19685 |
arg2Of |
D,and |
R14156 |
T19688 |
T19687 |
arg2Of |
Analysis,"," |
R14157 |
T19688 |
T19689 |
arg1Of |
Analysis,of |
R14158 |
T19691 |
T19689 |
arg2Of |
phenotypes,of |
R14159 |
T19691 |
T19690 |
arg1Of |
phenotypes,lymphocyte |
R1416 |
T2317 |
T2316 |
arg1Of |
genes,anti-apoptotic |
R14160 |
T19693 |
T19694 |
arg1Of |
tumor,and |
R14161 |
T19695 |
T19694 |
arg2Of |
spleen,and |
R14162 |
T19696 |
T19692 |
arg1Of |
tissues,The |
R14163 |
T19696 |
T19693 |
arg1Of |
tissues,tumor |
R14164 |
T19696 |
T19695 |
arg1Of |
tissues,spleen |
R14165 |
T19696 |
T19697 |
arg1Of |
tissues,were |
R14166 |
T19696 |
T19698 |
arg2Of |
tissues,separated |
R14167 |
T19698 |
T19697 |
arg2Of |
separated,were |
R14168 |
T19698 |
T19699 |
arg1Of |
separated,at |
R14169 |
T19701 |
T19699 |
arg2Of |
termination,at |
R1417 |
T2318 |
T2311 |
arg2Of |
and/or,and |
R14170 |
T19701 |
T19700 |
arg1Of |
termination,study |
R14171 |
T19701 |
T19702 |
arg1Of |
termination,( |
R14172 |
T19703 |
T19702 |
arg2Of |
Day,( |
R14173 |
T19703 |
T19704 |
arg1Of |
Day,31 |
R14174 |
T19705 |
T19702 |
arg3Of |
),( |
R14175 |
T19708 |
T19706 |
arg1Of |
analysis,Flow |
R14176 |
T19708 |
T19707 |
arg1Of |
analysis,cytometry |
R14177 |
T19708 |
T19709 |
arg1Of |
analysis,was |
R14178 |
T19708 |
T19710 |
arg2Of |
analysis,performed |
R14179 |
T19710 |
T19709 |
arg2Of |
performed,was |
R1418 |
T2335 |
T2327 |
arg1Of |
required,Although |
R14180 |
T19711 |
T19710 |
arg3Of |
using,performed |
R14181 |
T19712 |
T19711 |
arg2Of |
FACSAria,using |
R14182 |
T19712 |
T19719 |
modOf |
FACSAria,were |
R14183 |
T19714 |
T19713 |
arg1Of |
cytometry,flow |
R14184 |
T19714 |
T19716 |
arg1Of |
cytometry,and |
R14185 |
T19714 |
T19717 |
arg2Of |
cytometry,represent |
R14186 |
T19714 |
T19719 |
arg1Of |
cytometry,were |
R14187 |
T19714 |
T19720 |
arg2Of |
cytometry,shown |
R14188 |
T19716 |
T19715 |
arg1Of |
and,"," |
R14189 |
T19718 |
T19717 |
arg1Of |
data,represent |
R1419 |
T2335 |
T2332 |
arg1Of |
required,"," |
R14190 |
T19720 |
T19719 |
arg2Of |
shown,were |
R14191 |
T19721 |
T19722 |
arg1Of |
Data,are |
R14192 |
T19723 |
T19724 |
arg1Of |
means,± |
R14193 |
T19724 |
T19722 |
arg2Of |
±,are |
R14194 |
T19725 |
T19724 |
arg2Of |
S.D.,± |
R14195 |
T19725 |
T19726 |
arg1Of |
S.D.,of |
R14196 |
T19729 |
T19726 |
arg2Of |
animals,of |
R14197 |
T19729 |
T19727 |
arg1Of |
animals,four |
R14198 |
T19729 |
T19728 |
arg1Of |
animals,experimental |
R142 |
T362 |
T361 |
arg1Of |
inhibition,Significant |
R1420 |
T2335 |
T2334 |
arg2Of |
required,is |
R1421 |
T2335 |
T2336 |
arg1Of |
required,for |
R1422 |
T2320 |
T2318 |
arg2Of |
regulate,and/or |
R1423 |
T2339 |
T2336 |
arg2Of |
system,for |
R1424 |
T2339 |
T2337 |
arg1Of |
system,the |
R1425 |
T2339 |
T2338 |
arg1Of |
system,immune |
R1426 |
T2339 |
T2340 |
modOf |
system,to |
R1427 |
T2320 |
T2319 |
arg1Of |
regulate,down |
R1428 |
T2423 |
T2419 |
arg2Of |
death,affecting |
R1429 |
T2341 |
T2340 |
arg1Of |
function,to |
R143 |
T362 |
T363 |
arg1Of |
inhibition,of |
R1430 |
T2341 |
T2342 |
arg1Of |
function,normally |
R1431 |
T2341 |
T2343 |
arg1Of |
function,[ |
R1432 |
T2344 |
T2343 |
arg2Of |
29,[ |
R1433 |
T2345 |
T2343 |
arg3Of |
],[ |
R1434 |
T2346 |
T2347 |
arg1Of |
Studies,on |
R1435 |
T2346 |
T2350 |
arg1Of |
Studies,demonstrated |
R1436 |
T2349 |
T2347 |
arg2Of |
mice,on |
R1437 |
T2349 |
T2348 |
arg1Of |
mice,c-Rel-deficient |
R1438 |
T2423 |
T2420 |
arg1Of |
death,apoptotic |
R1439 |
T2423 |
T2421 |
arg1Of |
death,cancer |
R144 |
T362 |
T370 |
arg1Of |
inhibition,and |
R1440 |
T2423 |
T2422 |
arg1Of |
death,cell |
R1441 |
T2423 |
T2424 |
arg1Of |
death,"," |
R1442 |
T2423 |
T2425 |
arg1Of |
death,( |
R1443 |
T2352 |
T2353 |
arg1Of |
c-Rel,is |
R1444 |
T2352 |
T2354 |
arg1Of |
c-Rel,essential |
R1445 |
T2353 |
T2350 |
arg2Of |
is,demonstrated |
R1446 |
T2353 |
T2351 |
arg1Of |
is,that |
R1447 |
T2353 |
T2368 |
arg1Of |
is,[ |
R1448 |
T2354 |
T2353 |
arg2Of |
essential,is |
R1449 |
T2354 |
T2355 |
arg1Of |
essential,for |
R145 |
T366 |
T363 |
arg2Of |
activity,of |
R1450 |
T2356 |
T2357 |
arg1Of |
IL-2,"," |
R1451 |
T2357 |
T2359 |
arg1Of |
",","," |
R1452 |
T2358 |
T2357 |
arg2Of |
IL-3,"," |
R1453 |
T2359 |
T2362 |
arg1Of |
",",and |
R1454 |
T2423 |
T2428 |
arg1Of |
death,stimulating |
R1455 |
T2360 |
T2359 |
arg2Of |
GM-CSF,"," |
R1456 |
T2423 |
T2433 |
arg1Of |
death,or |
R1457 |
T2423 |
T2434 |
arg1Of |
death,( |
R1458 |
T2362 |
T2355 |
arg2Of |
and,for |
R1459 |
T2362 |
T2361 |
arg1Of |
and,"," |
R146 |
T366 |
T364 |
arg1Of |
activity,DNA |
R1460 |
T2362 |
T2365 |
arg1Of |
and,in |
R1461 |
T2423 |
T2437 |
arg1Of |
death,increasing |
R1462 |
T2364 |
T2362 |
arg2Of |
expression,and |
R1463 |
T2364 |
T2363 |
arg1Of |
expression,IFNγ |
R1464 |
T2426 |
T2425 |
arg2Of |
2,( |
R1465 |
T2367 |
T2365 |
arg2Of |
lymphocytes,in |
R1466 |
T2367 |
T2366 |
arg1Of |
lymphocytes,T |
R1467 |
T2369 |
T2368 |
arg2Of |
30,[ |
R1468 |
T2370 |
T2368 |
arg3Of |
],[ |
R1469 |
T2427 |
T2425 |
arg3Of |
),( |
R147 |
T366 |
T365 |
arg1Of |
activity,binding |
R1470 |
T2372 |
T2371 |
arg1Of |
mice,C-Rel-deficient |
R1471 |
T2372 |
T2374 |
arg1Of |
mice,have |
R1472 |
T2432 |
T2428 |
arg2Of |
infiltration,stimulating |
R1473 |
T2374 |
T2373 |
arg1Of |
have,also |
R1474 |
T2374 |
T2384 |
arg1Of |
have,in |
R1475 |
T2377 |
T2374 |
arg2Of |
deficiency,have |
R1476 |
T2377 |
T2375 |
arg1Of |
deficiency,a |
R1477 |
T2377 |
T2376 |
arg1Of |
deficiency,tissue-specific |
R1478 |
T2377 |
T2378 |
arg1Of |
deficiency,of |
R1479 |
T2380 |
T2379 |
arg1Of |
cytokines,various |
R148 |
T366 |
T367 |
arg1Of |
activity,of |
R1480 |
T2380 |
T2381 |
arg1Of |
cytokines,and |
R1481 |
T2381 |
T2378 |
arg2Of |
and,of |
R1482 |
T2432 |
T2429 |
arg1Of |
infiltration,tumor |
R1483 |
T2383 |
T2381 |
arg2Of |
factors,and |
R1484 |
T2383 |
T2382 |
arg1Of |
factors,growth |
R1485 |
T2432 |
T2430 |
arg1Of |
infiltration,killing |
R1486 |
T2432 |
T2431 |
arg1Of |
infiltration,lymphocytes |
R1487 |
T2435 |
T2434 |
arg2Of |
3,( |
R1488 |
T2386 |
T2385 |
arg1Of |
cells,T |
R1489 |
T2386 |
T2387 |
arg1Of |
cells,and |
R149 |
T368 |
T367 |
arg2Of |
NF-κB,of |
R1490 |
T2387 |
T2384 |
arg2Of |
and,in |
R1491 |
T2387 |
T2389 |
arg1Of |
and,affecting |
R1492 |
T2388 |
T2387 |
arg2Of |
macrophages,and |
R1493 |
T2389 |
T2396 |
arg1Of |
affecting,in |
R1494 |
T2389 |
T2399 |
arg1Of |
affecting,[ |
R1495 |
T2391 |
T2392 |
arg1Of |
innate,and |
R1496 |
T2436 |
T2434 |
arg3Of |
),( |
R1497 |
T2392 |
T2390 |
arg1Of |
and,both |
R1498 |
T2393 |
T2392 |
arg2Of |
humoral,and |
R1499 |
T2395 |
T2389 |
arg2Of |
responses,affecting |
R150 |
T370 |
T369 |
arg1Of |
and,"," |
R1500 |
T2395 |
T2391 |
arg1Of |
responses,innate |
R1501 |
T2395 |
T2393 |
arg1Of |
responses,humoral |
R1502 |
T2395 |
T2394 |
arg1Of |
responses,immune |
R1503 |
T2398 |
T2396 |
arg2Of |
host,in |
R1504 |
T2398 |
T2397 |
arg1Of |
host,the |
R1505 |
T2439 |
T2437 |
arg2Of |
production,increasing |
R1506 |
T2400 |
T2399 |
arg2Of |
31,[ |
R1507 |
T2401 |
T2399 |
arg3Of |
],[ |
R1508 |
T2439 |
T2438 |
arg1Of |
production,the |
R1509 |
T2404 |
T2405 |
arg1Of |
NF-κB,can |
R151 |
T370 |
T379 |
arg1Of |
and,through |
R1510 |
T2404 |
T2406 |
arg1Of |
NF-κB,be |
R1511 |
T2404 |
T2408 |
arg2Of |
NF-κB,targeted |
R1512 |
T2404 |
T2410 |
arg1Of |
NF-κB,prevent |
R1513 |
T2439 |
T2440 |
arg1Of |
production,of |
R1514 |
T2443 |
T2440 |
arg2Of |
lymphokines,of |
R1515 |
T2404 |
T2419 |
arg1Of |
NF-κB,affecting |
R1516 |
T2443 |
T2441 |
arg1Of |
lymphokines,tumor |
R1517 |
T2408 |
T2402 |
arg1Of |
targeted,Therefore |
R1518 |
T2408 |
T2403 |
arg1Of |
targeted,"," |
R1519 |
T2408 |
T2405 |
arg2Of |
targeted,can |
R152 |
T370 |
T386 |
arg1Of |
and,was |
R1520 |
T2408 |
T2406 |
arg2Of |
targeted,be |
R1521 |
T2408 |
T2407 |
arg1Of |
targeted,specially |
R1522 |
T2410 |
T2408 |
arg3Of |
prevent,targeted |
R1523 |
T2410 |
T2409 |
arg1Of |
prevent,to |
R1524 |
T2410 |
T2414 |
arg1Of |
prevent,by |
R1525 |
T2443 |
T2442 |
arg1Of |
lymphokines,killing |
R1526 |
T2444 |
T2445 |
arg1Of |
Activation,of |
R1527 |
T2413 |
T2410 |
arg2Of |
growth,prevent |
R1528 |
T2413 |
T2411 |
arg1Of |
growth,cancer |
R1529 |
T2413 |
T2412 |
arg1Of |
growth,cell |
R153 |
T370 |
T387 |
arg2Of |
and,found |
R1530 |
T2444 |
T2447 |
arg1Of |
Activation,is |
R1531 |
T2444 |
T2448 |
arg1Of |
Activation,important |
R1532 |
T2416 |
T2415 |
arg1Of |
1,( |
R1533 |
T2416 |
T2417 |
arg1Of |
1,) |
R1534 |
T2446 |
T2445 |
arg2Of |
NF-κB,of |
R1535 |
T2419 |
T2414 |
arg2Of |
affecting,by |
R1536 |
T2419 |
T2416 |
arg1Of |
affecting,1 |
R1537 |
T2419 |
T2418 |
arg1Of |
affecting,directly |
R1538 |
T2448 |
T2447 |
arg2Of |
important,is |
R1539 |
T2448 |
T2449 |
arg1Of |
important,in |
R154 |
T371 |
T370 |
arg2Of |
translocation,and |
R1540 |
T2451 |
T2449 |
arg2Of |
regulation,in |
R1541 |
T2451 |
T2450 |
arg1Of |
regulation,the |
R1542 |
T2451 |
T2452 |
arg1Of |
regulation,of |
R1543 |
T2455 |
T2456 |
arg1Of |
growth,and |
R1544 |
T2519 |
T2515 |
arg2Of |
development,in |
R1545 |
T2519 |
T2516 |
arg1Of |
development,CCR5 |
R1546 |
T2519 |
T2517 |
arg2Of |
development,mediated |
R1547 |
T2519 |
T2518 |
arg1Of |
development,tumor |
R1548 |
T2524 |
T2520 |
arg1Of |
sites,NF-κB |
R1549 |
T2524 |
T2521 |
arg1Of |
sites,transcription |
R155 |
T371 |
T372 |
arg1Of |
translocation,of |
R1550 |
T2524 |
T2522 |
arg1Of |
sites,factor |
R1551 |
T2524 |
T2523 |
arg1Of |
sites,binding |
R1552 |
T2524 |
T2525 |
arg1Of |
sites,are |
R1553 |
T2524 |
T2526 |
arg1Of |
sites,present |
R1554 |
T2456 |
T2452 |
arg2Of |
and,of |
R1555 |
T2526 |
T2525 |
arg2Of |
present,are |
R1556 |
T2526 |
T2527 |
arg1Of |
present,in |
R1557 |
T2456 |
T2453 |
arg1Of |
and,CCR-mediated |
R1558 |
T2456 |
T2454 |
arg1Of |
and,tumor |
R1559 |
T2530 |
T2527 |
arg2Of |
region,in |
R156 |
T371 |
T376 |
arg1Of |
translocation,into |
R1560 |
T2530 |
T2528 |
arg1Of |
region,the |
R1561 |
T2530 |
T2529 |
arg1Of |
region,promoter |
R1562 |
T2530 |
T2531 |
arg1Of |
region,of |
R1563 |
T2457 |
T2456 |
arg2Of |
metastasis,and |
R1564 |
T2534 |
T2531 |
arg2Of |
genes,of |
R1565 |
T2534 |
T2532 |
arg1Of |
genes,proinflammatory |
R1566 |
T2534 |
T2533 |
arg1Of |
genes,cytokine |
R1567 |
T2534 |
T2535 |
arg1Of |
genes,"," |
R1568 |
T2534 |
T2537 |
arg1Of |
genes,as |
R1569 |
T2458 |
T2459 |
arg1Of |
It,was |
R157 |
T373 |
T374 |
arg1Of |
p50,and |
R1570 |
T2537 |
T2536 |
arg1Of |
as,such |
R1571 |
T2538 |
T2539 |
arg1Of |
IL-1alpha,"," |
R1572 |
T2458 |
T2460 |
arg2Of |
It,reported |
R1573 |
T2539 |
T2541 |
arg1Of |
",","," |
R1574 |
T2540 |
T2539 |
arg2Of |
IL-6,"," |
R1575 |
T2460 |
T2459 |
arg2Of |
reported,was |
R1576 |
T2541 |
T2544 |
arg1Of |
",",and |
R1577 |
T2542 |
T2541 |
arg2Of |
GM-CSF,"," |
R1578 |
T2544 |
T2537 |
arg2Of |
and,as |
R1579 |
T2544 |
T2543 |
arg1Of |
and,"," |
R158 |
T374 |
T372 |
arg2Of |
and,of |
R1580 |
T2545 |
T2544 |
arg2Of |
KC,and |
R1581 |
T2545 |
T2546 |
arg1Of |
KC,[ |
R1582 |
T2462 |
T2463 |
arg1Of |
inhibition,of |
R1583 |
T2547 |
T2546 |
arg2Of |
34,[ |
R1584 |
T2548 |
T2546 |
arg3Of |
],[ |
R1585 |
T2462 |
T2465 |
arg1Of |
inhibition,by |
R1586 |
T2462 |
T2470 |
arg1Of |
inhibition,induces |
R1587 |
T2464 |
T2463 |
arg2Of |
NF-κB,of |
R1588 |
T2552 |
T2549 |
arg2Of |
hand,On |
R1589 |
T2552 |
T2550 |
arg1Of |
hand,the |
R159 |
T375 |
T374 |
arg2Of |
p65,and |
R1590 |
T2552 |
T2551 |
arg1Of |
hand,other |
R1591 |
T2555 |
T2554 |
arg1Of |
IL-1Ra,the |
R1592 |
T2555 |
T2556 |
arg1Of |
IL-1Ra,is |
R1593 |
T2556 |
T2549 |
arg1Of |
is,On |
R1594 |
T2556 |
T2553 |
arg1Of |
is,"," |
R1595 |
T2466 |
T2465 |
arg2Of |
dehydroxymethyl-epoxyquinomicin,by |
R1596 |
T2559 |
T2556 |
arg2Of |
regulator,is |
R1597 |
T2559 |
T2557 |
arg1Of |
regulator,a |
R1598 |
T2559 |
T2558 |
arg1Of |
regulator,negative |
R1599 |
T2559 |
T2560 |
arg1Of |
regulator,of |
R160 |
T378 |
T376 |
arg2Of |
nucleus,into |
R1600 |
T2563 |
T2560 |
arg2Of |
response,of |
R1601 |
T2563 |
T2561 |
arg1Of |
response,the |
R1602 |
T2466 |
T2467 |
arg1Of |
dehydroxymethyl-epoxyquinomicin,( |
R1603 |
T2468 |
T2467 |
arg2Of |
DHMEQ,( |
R1604 |
T2563 |
T2562 |
arg1Of |
response,inflammatory |
R1605 |
T2565 |
T2564 |
arg1Of |
studies,Several |
R1606 |
T2565 |
T2566 |
arg1Of |
studies,have |
R1607 |
T2565 |
T2567 |
arg1Of |
studies,demonstrated |
R1608 |
T2567 |
T2566 |
arg2Of |
demonstrated,have |
R1609 |
T2469 |
T2467 |
arg3Of |
),( |
R161 |
T378 |
T377 |
arg1Of |
nucleus,the |
R1610 |
T2569 |
T2567 |
arg2Of |
ability,demonstrated |
R1611 |
T2569 |
T2568 |
arg1Of |
ability,the |
R1612 |
T2569 |
T2570 |
arg1Of |
ability,of |
R1613 |
T2569 |
T2572 |
modOf |
ability,to |
R1614 |
T2470 |
T2460 |
arg3Of |
induces,reported |
R1615 |
T2571 |
T2570 |
arg2Of |
IL-1Ra,of |
R1616 |
T2470 |
T2461 |
arg1Of |
induces,that |
R1617 |
T2573 |
T2572 |
arg1Of |
abrogate,to |
R1618 |
T2470 |
T2477 |
arg1Of |
induces,by |
R1619 |
T2470 |
T2482 |
arg1Of |
induces,[ |
R162 |
T381 |
T379 |
arg2Of |
inhibition,through |
R1620 |
T2576 |
T2573 |
arg2Of |
effects,abrogate |
R1621 |
T2576 |
T2574 |
arg1Of |
effects,the |
R1622 |
T2576 |
T2575 |
arg1Of |
effects,proinflammatory |
R1623 |
T2576 |
T2577 |
arg1Of |
effects,of |
R1624 |
T2472 |
T2470 |
arg2Of |
death,induces |
R1625 |
T2578 |
T2577 |
arg2Of |
IL-1,of |
R1626 |
T2579 |
T2581 |
arg1Of |
Smith,al. |
R1627 |
T2579 |
T2582 |
arg1Of |
Smith,suggested |
R1628 |
T2581 |
T2580 |
arg1Of |
al.,et |
R1629 |
T2472 |
T2471 |
arg1Of |
death,cell |
R163 |
T381 |
T380 |
arg1Of |
inhibition,the |
R1630 |
T2472 |
T2473 |
arg1Of |
death,of |
R1631 |
T2476 |
T2473 |
arg2Of |
lymphoma,of |
R1632 |
T2585 |
T2584 |
arg1Of |
regulation,the |
R1633 |
T2585 |
T2586 |
arg1Of |
regulation,of |
R1634 |
T2585 |
T2590 |
arg1Of |
regulation,is |
R1635 |
T2589 |
T2586 |
arg2Of |
expression,of |
R1636 |
T2589 |
T2587 |
arg1Of |
expression,IL-1Ra |
R1637 |
T2589 |
T2588 |
arg1Of |
expression,gene |
R1638 |
T2590 |
T2582 |
arg2Of |
is,suggested |
R1639 |
T2590 |
T2583 |
arg1Of |
is,that |
R164 |
T381 |
T382 |
arg1Of |
inhibition,of |
R1640 |
T2590 |
T2607 |
arg1Of |
is,[ |
R1641 |
T2476 |
T2474 |
arg1Of |
lymphoma,primary |
R1642 |
T2476 |
T2475 |
arg1Of |
lymphoma,effusion |
R1643 |
T2593 |
T2590 |
arg2Of |
event,is |
R1644 |
T2593 |
T2591 |
arg1Of |
event,a |
R1645 |
T2593 |
T2592 |
arg1Of |
event,complex |
R1646 |
T2593 |
T2594 |
arg1Of |
event,involving |
R1647 |
T2593 |
T2602 |
arg1Of |
event,; |
R1648 |
T2478 |
T2477 |
arg2Of |
inhibition,by |
R1649 |
T2596 |
T2594 |
arg2Of |
interactions,involving |
R165 |
T383 |
T382 |
arg2Of |
phosphorylation,of |
R1650 |
T2596 |
T2595 |
arg1Of |
interactions,the |
R1651 |
T2596 |
T2597 |
arg1Of |
interactions,of |
R1652 |
T2601 |
T2597 |
arg2Of |
factors,of |
R1653 |
T2601 |
T2598 |
arg1Of |
factors,three |
R1654 |
T2601 |
T2599 |
arg1Of |
factors,different |
R1655 |
T2601 |
T2600 |
arg1Of |
factors,transcription |
R1656 |
T2478 |
T2479 |
arg1Of |
inhibition,of |
R1657 |
T2481 |
T2479 |
arg2Of |
expression,of |
R1658 |
T2606 |
T2602 |
arg2Of |
site,; |
R1659 |
T2606 |
T2603 |
arg1Of |
site,NF-κB/PU.1/GA-binding |
R166 |
T383 |
T384 |
arg1Of |
phosphorylation,of |
R1660 |
T2606 |
T2604 |
arg1Of |
site,protein |
R1661 |
T2606 |
T2605 |
arg1Of |
site,binding |
R1662 |
T2608 |
T2607 |
arg2Of |
35,[ |
R1663 |
T2609 |
T2607 |
arg3Of |
],[ |
R1664 |
T2481 |
T2480 |
arg1Of |
expression,CCR5 |
R1665 |
T2611 |
T2610 |
arg1Of |
translocation,Nuclear |
R1666 |
T2611 |
T2612 |
arg1Of |
translocation,of |
R1667 |
T2611 |
T2617 |
arg1Of |
translocation,was |
R1668 |
T2611 |
T2619 |
arg2Of |
translocation,enhanced |
R1669 |
T2611 |
T2621 |
arg2Of |
translocation,prolonged |
R167 |
T385 |
T384 |
arg2Of |
IκB,of |
R1670 |
T2613 |
T2612 |
arg2Of |
NF-κB,of |
R1671 |
T2613 |
T2614 |
arg1Of |
NF-κB,( |
R1672 |
T2483 |
T2482 |
arg2Of |
32,[ |
R1673 |
T2484 |
T2482 |
arg3Of |
],[ |
R1674 |
T2615 |
T2614 |
arg2Of |
p65,( |
R1675 |
T2485 |
T2486 |
arg1Of |
Activation,of |
R1676 |
T2616 |
T2614 |
arg3Of |
),( |
R1677 |
T2485 |
T2489 |
arg1Of |
Activation,increases |
R1678 |
T2619 |
T2620 |
arg1Of |
enhanced,and |
R1679 |
T2487 |
T2486 |
arg2Of |
NF-κB,of |
R168 |
T387 |
T386 |
arg2Of |
found,was |
R1680 |
T2620 |
T2617 |
arg2Of |
and,was |
R1681 |
T2620 |
T2618 |
arg1Of |
and,significantly |
R1682 |
T2620 |
T2622 |
arg1Of |
and,in |
R1683 |
T2620 |
T2625 |
arg1Of |
and,"," |
R1684 |
T2620 |
T2626 |
arg1Of |
and,compared |
R1685 |
T2621 |
T2620 |
arg2Of |
prolonged,and |
R1686 |
T2624 |
T2622 |
arg2Of |
mice,in |
R1687 |
T2624 |
T2623 |
arg1Of |
mice,IL-1Ra-deficient |
R1688 |
T2489 |
T2488 |
arg1Of |
increases,also |
R1689 |
T2627 |
T2626 |
arg2Of |
to,compared |
R169 |
T387 |
T388 |
arg1Of |
found,in |
R1690 |
T2628 |
T2627 |
arg2Of |
that,to |
R1691 |
T2628 |
T2629 |
arg1Of |
that,in |
R1692 |
T2493 |
T2490 |
arg1Of |
motility,CCL5-mediated |
R1693 |
T2632 |
T2629 |
arg2Of |
mice,in |
R1694 |
T2632 |
T2630 |
arg1Of |
mice,wild |
R1695 |
T2632 |
T2631 |
arg1Of |
mice,type |
R1696 |
T2632 |
T2633 |
arg1Of |
mice,[ |
R1697 |
T2634 |
T2633 |
arg2Of |
36,[ |
R1698 |
T2635 |
T2633 |
arg3Of |
],[ |
R1699 |
T2637 |
T2636 |
arg1Of |
IL-1Ra,Intracellular |
R170 |
T387 |
T395 |
arg1Of |
found,compared |
R1700 |
T2637 |
T2638 |
arg1Of |
IL-1Ra,( |
R1701 |
T2637 |
T2641 |
arg1Of |
IL-1Ra,was |
R1702 |
T2637 |
T2642 |
arg2Of |
IL-1Ra,found |
R1703 |
T2637 |
T2644 |
arg1Of |
IL-1Ra,inhibit |
R1704 |
T2637 |
T2647 |
arg1Of |
IL-1Ra,blocking |
R1705 |
T2493 |
T2491 |
arg1Of |
motility,oral |
R1706 |
T2639 |
T2638 |
arg2Of |
icIL-1Ra,( |
R1707 |
T2493 |
T2492 |
arg1Of |
motility,cancer |
R1708 |
T2640 |
T2638 |
arg3Of |
),( |
R1709 |
T2493 |
T2494 |
arg1Of |
motility,( |
R171 |
T391 |
T388 |
arg2Of |
tissues,in |
R1710 |
T2642 |
T2641 |
arg2Of |
found,was |
R1711 |
T2493 |
T2497 |
arg1Of |
motility,and |
R1712 |
T2495 |
T2494 |
arg2Of |
5,( |
R1713 |
T2644 |
T2642 |
arg3Of |
inhibit,found |
R1714 |
T2644 |
T2643 |
arg1Of |
inhibit,to |
R1715 |
T2644 |
T2646 |
arg1Of |
inhibit,by |
R1716 |
T2645 |
T2644 |
arg2Of |
IL-1,inhibit |
R1717 |
T2647 |
T2646 |
arg2Of |
blocking,by |
R1718 |
T2496 |
T2494 |
arg3Of |
),( |
R1719 |
T2651 |
T2647 |
arg2Of |
pathways,blocking |
R172 |
T391 |
T389 |
arg1Of |
tissues,the |
R1720 |
T2651 |
T2648 |
arg1Of |
pathways,NF-κB |
R1721 |
T2651 |
T2649 |
arg1Of |
pathways,signal |
R1722 |
T2651 |
T2650 |
arg1Of |
pathways,transduction |
R1723 |
T2651 |
T2652 |
arg1Of |
pathways,in |
R1724 |
T2497 |
T2489 |
arg2Of |
and,increases |
R1725 |
T2654 |
T2652 |
arg2Of |
responses,in |
R1726 |
T2654 |
T2653 |
arg1Of |
responses,inflammatory |
R1727 |
T2654 |
T2655 |
arg1Of |
responses,[ |
R1728 |
T2499 |
T2497 |
arg2Of |
metastasis,and |
R1729 |
T2656 |
T2655 |
arg2Of |
37,[ |
R173 |
T391 |
T390 |
arg1Of |
tissues,melanoma |
R1730 |
T2657 |
T2655 |
arg3Of |
],[ |
R1731 |
T2659 |
T2660 |
arg1Of |
IL-1,has |
R1732 |
T2659 |
T2661 |
arg1Of |
IL-1,been |
R1733 |
T2659 |
T2662 |
arg2Of |
IL-1,shown |
R1734 |
T2659 |
T2664 |
arg1Of |
IL-1,be |
R1735 |
T2499 |
T2498 |
arg1Of |
metastasis,lung |
R1736 |
T2662 |
T2658 |
arg2Of |
shown,Because |
R1737 |
T2662 |
T2660 |
arg2Of |
shown,has |
R1738 |
T2662 |
T2661 |
arg2Of |
shown,been |
R1739 |
T2499 |
T2500 |
arg1Of |
metastasis,[ |
R174 |
T391 |
T392 |
arg1Of |
tissues,of |
R1740 |
T2664 |
T2662 |
arg3Of |
be,shown |
R1741 |
T2664 |
T2663 |
arg1Of |
be,to |
R1742 |
T2501 |
T2500 |
arg2Of |
33,[ |
R1743 |
T2666 |
T2664 |
arg2Of |
inducer,be |
R1744 |
T2666 |
T2665 |
arg1Of |
inducer,an |
R1745 |
T2666 |
T2667 |
arg1Of |
inducer,of |
R1746 |
T2669 |
T2667 |
arg2Of |
activation,of |
R1747 |
T2669 |
T2668 |
arg1Of |
activation,NF-κB |
R1748 |
T2669 |
T2670 |
arg1Of |
activation,[ |
R1749 |
T2502 |
T2500 |
arg3Of |
],[ |
R175 |
T394 |
T392 |
arg2Of |
mice,of |
R1750 |
T2671 |
T2670 |
arg2Of |
38,[ |
R1751 |
T2672 |
T2670 |
arg3Of |
],[ |
R1752 |
T2674 |
T2675 |
arg1Of |
we,hypothesized |
R1753 |
T2675 |
T2658 |
arg1Of |
hypothesized,Because |
R1754 |
T2675 |
T2673 |
arg1Of |
hypothesized,"," |
R1755 |
T2506 |
T2503 |
arg1Of |
is,Thus |
R1756 |
T2678 |
T2677 |
arg1Of |
expression,the |
R1757 |
T2678 |
T2679 |
arg1Of |
expression,of |
R1758 |
T2678 |
T2681 |
arg1Of |
expression,could |
R1759 |
T2678 |
T2682 |
arg1Of |
expression,play |
R176 |
T394 |
T393 |
arg1Of |
mice,CCR5−/− |
R1760 |
T2680 |
T2679 |
arg2Of |
IL-1Ra,of |
R1761 |
T2682 |
T2675 |
arg2Of |
play,hypothesized |
R1762 |
T2682 |
T2676 |
arg1Of |
play,that |
R1763 |
T2682 |
T2681 |
arg2Of |
play,could |
R1764 |
T2682 |
T2686 |
arg1Of |
play,in |
R1765 |
T2685 |
T2682 |
arg2Of |
role,play |
R1766 |
T2685 |
T2683 |
arg1Of |
role,an |
R1767 |
T2685 |
T2684 |
arg1Of |
role,important |
R1768 |
T2506 |
T2504 |
arg1Of |
is,"," |
R1769 |
T2507 |
T2506 |
arg2Of |
possible,is |
R177 |
T396 |
T395 |
arg2Of |
to,compared |
R1770 |
T2689 |
T2686 |
arg2Of |
activation,in |
R1771 |
T2689 |
T2687 |
arg1Of |
activation,the |
R1772 |
T2689 |
T2688 |
arg1Of |
activation,autocrine |
R1773 |
T2689 |
T2690 |
arg1Of |
activation,of |
R1774 |
T2509 |
T2510 |
arg1Of |
inhibition,of |
R1775 |
T2692 |
T2691 |
arg1Of |
factors,transcription |
R1776 |
T2693 |
T2694 |
arg1Of |
NF-κB,or |
R1777 |
T2694 |
T2690 |
arg2Of |
or,of |
R1778 |
T2694 |
T2692 |
arg1Of |
or,factors |
R1779 |
T2509 |
T2512 |
arg1Of |
inhibition,could |
R178 |
T398 |
T396 |
arg2Of |
tissues,to |
R1780 |
T2509 |
T2513 |
arg1Of |
inhibition,be |
R1781 |
T2696 |
T2694 |
arg2Of |
versa,or |
R1782 |
T2696 |
T2695 |
arg1Of |
versa,vice |
R1783 |
T2509 |
T2514 |
arg2Of |
inhibition,involved |
R1784 |
T2511 |
T2510 |
arg2Of |
NF-κB,of |
R1785 |
T2700 |
T2699 |
arg1Of |
aim,the |
R1786 |
T2700 |
T2701 |
arg1Of |
aim,of |
R1787 |
T2700 |
T2704 |
arg1Of |
aim,was |
R1788 |
T2703 |
T2701 |
arg2Of |
study,of |
R1789 |
T2703 |
T2702 |
arg1Of |
study,this |
R179 |
T398 |
T397 |
arg1Of |
tissues,melanoma |
R1790 |
T2704 |
T2697 |
arg1Of |
was,Thus |
R1791 |
T2704 |
T2698 |
arg1Of |
was,"," |
R1792 |
T2514 |
T2505 |
arg1Of |
involved,it |
R1793 |
T2706 |
T2704 |
arg2Of |
evaluate,was |
R1794 |
T2706 |
T2705 |
arg1Of |
evaluate,to |
R1795 |
T2708 |
T2706 |
arg2Of |
roles,evaluate |
R1796 |
T2708 |
T2707 |
arg1Of |
roles,the |
R1797 |
T2708 |
T2709 |
arg1Of |
roles,of |
R1798 |
T2708 |
T2713 |
arg1Of |
roles,in |
R1799 |
T2514 |
T2506 |
arg1Of |
involved,is |
R180 |
T398 |
T399 |
arg1Of |
tissues,of |
R1800 |
T2710 |
T2711 |
arg1Of |
NF-κB,and |
R1801 |
T2514 |
T2507 |
arg1Of |
involved,possible |
R1802 |
T2514 |
T2508 |
arg1Of |
involved,that |
R1803 |
T2514 |
T2512 |
arg2Of |
involved,could |
R1804 |
T2514 |
T2513 |
arg2Of |
involved,be |
R1805 |
T2514 |
T2515 |
arg1Of |
involved,in |
R1807 |
T2711 |
T2709 |
arg2Of |
and,of |
R1808 |
T2712 |
T2711 |
arg2Of |
IL-1Ra,and |
R1809 |
T2718 |
T2713 |
arg2Of |
suppression,in |
R181 |
T401 |
T399 |
arg2Of |
mice,of |
R1810 |
T2718 |
T2714 |
arg1Of |
suppression,the |
R1811 |
T2718 |
T2715 |
arg1Of |
suppression,chemokine |
R1812 |
T2718 |
T2716 |
arg1Of |
suppression,receptor |
R1813 |
T2718 |
T2717 |
arg1Of |
suppression,CCR5-mediated |
R1814 |
T2718 |
T2719 |
arg1Of |
suppression,of |
R1815 |
T2721 |
T2719 |
arg2Of |
development,of |
R1816 |
T2721 |
T2720 |
arg1Of |
development,tumor |
R182 |
T401 |
T400 |
arg1Of |
mice,CCR5+/+ |
R183 |
T406 |
T402 |
arg1Of |
expression,NF-κB |
R184 |
T406 |
T403 |
arg1Of |
expression,target |
R185 |
T406 |
T404 |
arg1Of |
expression,apoptotic |
R186 |
T406 |
T405 |
arg1Of |
expression,protein |
R187 |
T406 |
T407 |
arg1Of |
expression,"," |
R188 |
T406 |
T409 |
arg1Of |
expression,as |
R189 |
T406 |
T419 |
arg1Of |
expression,was |
R190 |
T406 |
T420 |
arg2Of |
expression,elevated |
R191 |
T409 |
T408 |
arg1Of |
as,such |
R192 |
T411 |
T410 |
arg2Of |
caspase-3,cleaved |
R193 |
T411 |
T413 |
arg2Of |
caspase-3,cleaved |
R194 |
T411 |
T416 |
arg1Of |
caspase-3,and |
R195 |
T413 |
T412 |
arg1Of |
cleaved,"," |
R196 |
T414 |
T413 |
arg3Of |
PARP,cleaved |
R197 |
T416 |
T409 |
arg2Of |
and,as |
R198 |
T416 |
T415 |
arg1Of |
and,"," |
R199 |
T417 |
T416 |
arg2Of |
Bax,and |
R200 |
T420 |
T418 |
arg1Of |
elevated,"," |
R201 |
T420 |
T419 |
arg2Of |
elevated,was |
R202 |
T420 |
T421 |
arg1Of |
elevated,"," |
R203 |
T420 |
T422 |
arg1Of |
elevated,whereas |
R204 |
T427 |
T423 |
arg1Of |
levels,the |
R205 |
T427 |
T424 |
arg1Of |
levels,survival |
R206 |
T427 |
T425 |
arg1Of |
levels,protein |
R207 |
T427 |
T426 |
arg1Of |
levels,expression |
R208 |
T427 |
T428 |
arg1Of |
levels,"," |
R209 |
T427 |
T430 |
arg1Of |
levels,as |
R210 |
T427 |
T435 |
arg1Of |
levels,was |
R211 |
T427 |
T436 |
arg2Of |
levels,decreased |
R212 |
T430 |
T429 |
arg1Of |
as,such |
R213 |
T431 |
T430 |
arg2Of |
Bcl-2,as |
R214 |
T431 |
T432 |
arg1Of |
Bcl-2,"," |
R215 |
T433 |
T432 |
arg2Of |
C-IAP1,"," |
R216 |
T436 |
T422 |
arg2Of |
decreased,whereas |
R217 |
T436 |
T434 |
arg1Of |
decreased,"," |
R218 |
T436 |
T435 |
arg2Of |
decreased,was |
R219 |
T436 |
T437 |
arg1Of |
decreased,in |
R220 |
T440 |
T437 |
arg2Of |
tissues,in |
R221 |
T440 |
T438 |
arg1Of |
tissues,the |
R222 |
T440 |
T439 |
arg1Of |
tissues,melanoma |
R223 |
T440 |
T441 |
arg1Of |
tissues,of |
R224 |
T443 |
T441 |
arg2Of |
mice,of |
R225 |
T443 |
T442 |
arg1Of |
mice,CCR5−/− |
R226 |
T446 |
T447 |
arg1Of |
we,found |
R227 |
T447 |
T444 |
arg1Of |
found,Interestingly |
R228 |
T447 |
T445 |
arg1Of |
found,"," |
R229 |
T450 |
T449 |
arg1Of |
level,the |
R230 |
T450 |
T451 |
arg1Of |
level,of |
R231 |
T450 |
T453 |
arg1Of |
level,"," |
R232 |
T450 |
T460 |
arg1Of |
level,was |
R233 |
T450 |
T462 |
arg2Of |
level,elevated |
R234 |
T452 |
T451 |
arg2Of |
IL-1Ra,of |
R235 |
T458 |
T453 |
arg2Of |
cytokine,"," |
R236 |
T458 |
T454 |
arg1Of |
cytokine,a |
R237 |
T458 |
T455 |
arg1Of |
cytokine,tumor |
R238 |
T458 |
T456 |
arg1Of |
cytokine,growth |
R239 |
T458 |
T457 |
arg1Of |
cytokine,suppressive |
R240 |
T462 |
T447 |
arg2Of |
elevated,found |
R241 |
T462 |
T448 |
arg1Of |
elevated,that |
R242 |
T462 |
T459 |
arg1Of |
elevated,"," |
R243 |
T462 |
T460 |
arg2Of |
elevated,was |
R244 |
T462 |
T461 |
arg1Of |
elevated,significantly |
R245 |
T462 |
T463 |
arg1Of |
elevated,in |
R246 |
T465 |
T464 |
arg1Of |
tissue,tumor |
R247 |
T465 |
T466 |
arg1Of |
tissue,and |
R248 |
T466 |
T463 |
arg2Of |
and,in |
R249 |
T466 |
T471 |
arg1Of |
and,compared |
R250 |
T467 |
T466 |
arg2Of |
spleen,and |
R251 |
T467 |
T468 |
arg1Of |
spleen,of |
R252 |
T470 |
T468 |
arg2Of |
mice,of |
R253 |
T470 |
T469 |
arg1Of |
mice,CCR5−/− |
R254 |
T472 |
T471 |
arg2Of |
to,compared |
R255 |
T474 |
T472 |
arg2Of |
level,to |
R256 |
T474 |
T473 |
arg1Of |
level,the |
R257 |
T474 |
T475 |
arg1Of |
level,in |
R258 |
T477 |
T475 |
arg2Of |
mice,in |
R259 |
T477 |
T476 |
arg1Of |
mice,CCR5+/+ |
R260 |
T480 |
T481 |
arg1Of |
infiltration,of |
R261 |
T480 |
T491 |
arg1Of |
infiltration,was |
R262 |
T480 |
T493 |
arg2Of |
infiltration,increased |
R263 |
T485 |
T482 |
arg1Of |
cell,CD8+ |
R264 |
T485 |
T483 |
arg1Of |
cell,cytotoxic |
R265 |
T485 |
T484 |
arg1Of |
cell,T |
R266 |
T485 |
T486 |
arg1Of |
cell,and |
R267 |
T486 |
T481 |
arg2Of |
and,of |
R268 |
T490 |
T486 |
arg2Of |
cells,and |
R269 |
T490 |
T487 |
arg1Of |
cells,CD57+ |
R270 |
T490 |
T488 |
arg1Of |
cells,natural |
R271 |
T490 |
T489 |
arg1Of |
cells,killer |
R272 |
T493 |
T478 |
arg1Of |
increased,Moreover |
R273 |
T493 |
T479 |
arg1Of |
increased,"," |
R274 |
T493 |
T491 |
arg2Of |
increased,was |
R275 |
T493 |
T492 |
arg1Of |
increased,significantly |
R276 |
T493 |
T494 |
arg1Of |
increased,in |
R277 |
T496 |
T497 |
arg1Of |
tumor,and |
R278 |
T498 |
T497 |
arg2Of |
spleen,and |
R279 |
T499 |
T494 |
arg2Of |
tissue,in |
R280 |
T499 |
T495 |
arg1Of |
tissue,melanoma |
R281 |
T499 |
T496 |
arg1Of |
tissue,tumor |
R282 |
T499 |
T498 |
arg1Of |
tissue,spleen |
R283 |
T499 |
T500 |
arg1Of |
tissue,of |
R284 |
T502 |
T500 |
arg2Of |
mice,of |
R285 |
T502 |
T501 |
arg1Of |
mice,CCR5−/− |
R286 |
T502 |
T503 |
arg2Of |
mice,compared |
R287 |
T503 |
T504 |
arg1Of |
compared,to |
R288 |
T505 |
T504 |
arg2Of |
that,to |
R289 |
T505 |
T506 |
arg1Of |
that,of |
R290 |
T508 |
T506 |
arg2Of |
mice,of |
R291 |
T508 |
T507 |
arg1Of |
mice,CCR5+/+ |
R292 |
T512 |
T511 |
arg1Of |
results,these |
R293 |
T512 |
T513 |
arg1Of |
results,showed |
R294 |
T513 |
T509 |
arg1Of |
showed,Therefore |
R295 |
T513 |
T510 |
arg1Of |
showed,"," |
R296 |
T516 |
T515 |
arg1Of |
deficiency,CCR5 |
R297 |
T516 |
T517 |
arg1Of |
deficiency,caused |
R298 |
T517 |
T513 |
arg2Of |
caused,showed |
R299 |
T517 |
T514 |
arg1Of |
caused,that |
R300 |
T517 |
T523 |
arg1Of |
caused,through |
R301 |
T520 |
T517 |
arg2Of |
death,caused |
R302 |
T520 |
T518 |
arg1Of |
death,apoptotic |
R303 |
T520 |
T519 |
arg1Of |
death,cell |
R304 |
T520 |
T521 |
arg1Of |
death,of |
R305 |
T522 |
T521 |
arg2Of |
melanoma,of |
R306 |
T524 |
T523 |
arg2Of |
inhibition,through |
R307 |
T524 |
T525 |
arg1Of |
inhibition,of |
R3070 |
T4601 |
T4602 |
arg1Of |
Inhibition,of |
R3071 |
T4601 |
T4605 |
arg1Of |
Inhibition,in |
R3072 |
T4604 |
T4602 |
arg2Of |
Development,of |
R3073 |
T4604 |
T4603 |
arg1Of |
Development,Tumor |
R3074 |
T4607 |
T4605 |
arg2Of |
Mice,in |
R3075 |
T4607 |
T4606 |
arg1Of |
Mice,CCR5−/− |
R3076 |
T4609 |
T4608 |
arg1Of |
effect,The |
R3077 |
T4609 |
T4610 |
arg1Of |
effect,of |
R3078 |
T4609 |
T4612 |
arg1Of |
effect,in |
R3079 |
T4609 |
T4615 |
arg1Of |
effect,was |
R308 |
T526 |
T527 |
arg1Of |
NF-κB,and |
R3080 |
T4609 |
T4616 |
arg2Of |
effect,investigated |
R3081 |
T4611 |
T4610 |
arg2Of |
CCR5,of |
R3082 |
T4614 |
T4612 |
arg2Of |
development,in |
R3083 |
T4614 |
T4613 |
arg1Of |
development,tumor |
R3084 |
T4616 |
T4615 |
arg2Of |
investigated,was |
R3085 |
T4617 |
T4616 |
arg3Of |
using,investigated |
R3086 |
T4618 |
T4619 |
arg1Of |
CCR5+/+,and |
R3087 |
T4619 |
T4617 |
arg2Of |
and,using |
R3088 |
T4621 |
T4619 |
arg2Of |
mice,and |
R3089 |
T4621 |
T4620 |
arg1Of |
mice,CCR5−/− |
R309 |
T527 |
T525 |
arg2Of |
and,of |
R3090 |
T4624 |
T4622 |
arg1Of |
cells,B16-F0 |
R3091 |
T4624 |
T4623 |
arg1Of |
cells,melanoma |
R3092 |
T4624 |
T4625 |
arg1Of |
cells,were |
R3093 |
T4624 |
T4626 |
arg2Of |
cells,inoculated |
R3094 |
T4626 |
T4625 |
arg2Of |
inoculated,were |
R3095 |
T4626 |
T4627 |
arg1Of |
inoculated,subcutaneously |
R3096 |
T4626 |
T4628 |
arg1Of |
inoculated,into |
R3097 |
T4629 |
T4630 |
arg1Of |
CCR5+/+,and |
R3098 |
T4631 |
T4630 |
arg2Of |
CCR5−/−,and |
R3099 |
T4632 |
T4628 |
arg2Of |
mice,into |
R310 |
T528 |
T527 |
arg2Of |
upregulation,and |
R3100 |
T4632 |
T4629 |
arg1Of |
mice,CCR5+/+ |
R3101 |
T4632 |
T4631 |
arg1Of |
mice,CCR5−/− |
R3102 |
T4632 |
T4633 |
arg1Of |
mice,( |
R3103 |
T4634 |
T4633 |
arg2Of |
n = 20,( |
R3104 |
T4635 |
T4633 |
arg3Of |
),( |
R3105 |
T4637 |
T4636 |
arg1Of |
growth,Tumor |
R3106 |
T4637 |
T4638 |
arg1Of |
growth,was |
R3107 |
T4637 |
T4639 |
arg2Of |
growth,monitored |
R3108 |
T4639 |
T4638 |
arg2Of |
monitored,was |
R3109 |
T4639 |
T4640 |
arg1Of |
monitored,for |
R311 |
T528 |
T529 |
arg1Of |
upregulation,of |
R3110 |
T4642 |
T4640 |
arg2Of |
days,for |
R3111 |
T4642 |
T4641 |
arg1Of |
days,31 |
R3112 |
T4644 |
T4643 |
arg1Of |
growth,Tumor |
R3113 |
T4644 |
T4645 |
arg1Of |
growth,in |
R3114 |
T4644 |
T4649 |
arg1Of |
growth,was |
R3115 |
T4644 |
T4651 |
arg1Of |
growth,lower |
R3116 |
T4648 |
T4645 |
arg2Of |
mice,in |
R3117 |
T4648 |
T4646 |
arg1Of |
mice,the |
R3118 |
T4648 |
T4647 |
arg1Of |
mice,CCR5−/− |
R3119 |
T4651 |
T4649 |
arg2Of |
lower,was |
R312 |
T530 |
T529 |
arg2Of |
IL-1Ra,of |
R3120 |
T4651 |
T4650 |
arg1Of |
lower,significantly |
R3121 |
T4651 |
T4652 |
arg1Of |
lower,than |
R3122 |
T4653 |
T4652 |
arg2Of |
that,than |
R3123 |
T4653 |
T4654 |
arg1Of |
that,in |
R3124 |
T4657 |
T4654 |
arg2Of |
mice,in |
R3125 |
T4657 |
T4655 |
arg1Of |
mice,the |
R3126 |
T4657 |
T4656 |
arg1Of |
mice,CCR5+/+ |
R3127 |
T4660 |
T4658 |
arg1Of |
growth,The |
R3128 |
T4660 |
T4659 |
arg1Of |
growth,tumor |
R3129 |
T4660 |
T4661 |
arg1Of |
growth,in |
R3130 |
T4660 |
T4665 |
arg1Of |
growth,was |
R3131 |
T4660 |
T4666 |
arg2Of |
growth,reduced |
R3132 |
T4664 |
T4661 |
arg2Of |
mice,in |
R3133 |
T4664 |
T4662 |
arg1Of |
mice,the |
R3134 |
T4664 |
T4663 |
arg1Of |
mice,CCR5−/− |
R3135 |
T4666 |
T4665 |
arg2Of |
reduced,was |
R3136 |
T4666 |
T4667 |
arg1Of |
reduced,to |
R3137 |
T4666 |
T4671 |
arg1Of |
reduced,whereas |
R3138 |
T4669 |
T4667 |
arg2Of |
%,to |
R3139 |
T4669 |
T4668 |
arg1Of |
%,19.1 |
R3140 |
T4671 |
T4670 |
arg1Of |
whereas,"," |
R3141 |
T4674 |
T4672 |
arg1Of |
growth,the |
R3142 |
T4674 |
T4673 |
arg1Of |
growth,tumor |
R3143 |
T4674 |
T4675 |
arg1Of |
growth,in |
R3144 |
T4674 |
T4679 |
arg1Of |
growth,was |
R3145 |
T4674 |
T4681 |
arg2Of |
growth,reduced |
R3146 |
T4678 |
T4675 |
arg2Of |
mice,in |
R3147 |
T4678 |
T4676 |
arg1Of |
mice,the |
R3148 |
T4678 |
T4677 |
arg1Of |
mice,CCR5+/+ |
R3149 |
T4681 |
T4671 |
arg2Of |
reduced,whereas |
R3150 |
T4681 |
T4679 |
arg2Of |
reduced,was |
R3151 |
T4681 |
T4680 |
arg1Of |
reduced,only |
R3152 |
T4681 |
T4682 |
arg1Of |
reduced,to |
R3153 |
T4681 |
T4685 |
arg1Of |
reduced,"," |
R3154 |
T4681 |
T4686 |
arg1Of |
reduced,in |
R3155 |
T4684 |
T4682 |
arg2Of |
%,to |
R3156 |
T4684 |
T4683 |
arg1Of |
%,24.3 |
R3157 |
T4689 |
T4687 |
arg1Of |
weight,both |
R3158 |
T4689 |
T4688 |
arg1Of |
weight,tumor |
R3159 |
T4689 |
T4690 |
arg1Of |
weight,( |
R3160 |
T4689 |
T4696 |
arg1Of |
weight,and |
R3161 |
T4692 |
T4691 |
arg1Of |
1A,Figure |
R3162 |
T4692 |
T4693 |
arg1Of |
1A,and |
R3163 |
T4693 |
T4690 |
arg2Of |
and,( |
R3164 |
T4694 |
T4693 |
arg2Of |
1B,and |
R3165 |
T4695 |
T4690 |
arg3Of |
),( |
R3166 |
T4696 |
T4686 |
arg2Of |
and,in |
R3167 |
T4698 |
T4696 |
arg2Of |
volume,and |
R3168 |
T4698 |
T4697 |
arg1Of |
volume,tumor |
R3169 |
T4698 |
T4699 |
arg1Of |
volume,"," |
R3170 |
T4698 |
T4700 |
arg1Of |
volume,respectively |
R3171 |
T4698 |
T4701 |
arg1Of |
volume,( |
R3172 |
T4703 |
T4702 |
arg1Of |
1A,Figure |
R3173 |
T4703 |
T4704 |
arg1Of |
1A,and |
R3174 |
T4704 |
T4701 |
arg2Of |
and,( |
R3175 |
T4705 |
T4704 |
arg2Of |
1C,and |
R3176 |
T4706 |
T4701 |
arg3Of |
),( |
R3177 |
T4708 |
T4707 |
arg1Of |
results,These |
R3178 |
T4708 |
T4709 |
arg1Of |
results,correlated |
R3179 |
T4709 |
T4710 |
arg1Of |
correlated,with |
R3180 |
T4713 |
T4710 |
arg2Of |
rates,with |
R3181 |
T4713 |
T4711 |
arg1Of |
rates,mice |
R3182 |
T4713 |
T4712 |
arg1Of |
rates,survival |
R3183 |
T4714 |
T4715 |
arg1Of |
There,was |
R3184 |
T4715 |
T4719 |
arg1Of |
was,in |
R3185 |
T4718 |
T4715 |
arg2Of |
difference,was |
R3186 |
T4718 |
T4716 |
arg1Of |
difference,a |
R3187 |
T4718 |
T4717 |
arg1Of |
difference,significant |
R3188 |
T4721 |
T4719 |
arg2Of |
rates,in |
R3189 |
T4721 |
T4720 |
arg1Of |
rates,survival |
R3190 |
T4721 |
T4722 |
arg1Of |
rates,between |
R3191 |
T4721 |
T4739 |
arg1Of |
rates,at |
R3192 |
T4721 |
T4745 |
arg1Of |
rates,( |
R3193 |
T4724 |
T4723 |
arg1Of |
mice,CCR5−/− |
R3194 |
T4724 |
T4725 |
arg1Of |
mice,( |
R3195 |
T4724 |
T4732 |
arg1Of |
mice,and |
R3196 |
T4727 |
T4725 |
arg2Of |
%,( |
R3197 |
T4727 |
T4726 |
arg1Of |
%,75 |
R3198 |
T4727 |
T4728 |
arg1Of |
%,of |
R3199 |
T4729 |
T4728 |
arg2Of |
starting,of |
R3200 |
T4730 |
T4729 |
arg2Of |
time,starting |
R3201 |
T4731 |
T4725 |
arg3Of |
),( |
R3202 |
T4732 |
T4722 |
arg2Of |
and,between |
R3203 |
T4734 |
T4732 |
arg2Of |
mice,and |
R3204 |
T4734 |
T4733 |
arg1Of |
mice,CCR5+/+ |
R3205 |
T4734 |
T4735 |
arg1Of |
mice,( |
R3206 |
T4737 |
T4735 |
arg2Of |
%,( |
R3207 |
T4737 |
T4736 |
arg1Of |
%,15 |
R3208 |
T4738 |
T4735 |
arg3Of |
),( |
R3209 |
T4741 |
T4739 |
arg2Of |
end,at |
R3210 |
T4741 |
T4740 |
arg1Of |
end,the |
R3211 |
T4741 |
T4742 |
arg1Of |
end,of |
R3212 |
T4744 |
T4742 |
arg2Of |
experiment,of |
R3213 |
T4744 |
T4743 |
arg1Of |
experiment,the |
R3214 |
T4747 |
T4745 |
arg2Of |
1D,( |
R3215 |
T4747 |
T4746 |
arg1Of |
1D,Figure |
R3216 |
T4748 |
T4745 |
arg3Of |
),( |
R3217 |
T4749 |
T4750 |
arg1Of |
There,was |
R3218 |
T4753 |
T4750 |
arg2Of |
difference,was |
R3219 |
T4753 |
T4751 |
arg1Of |
difference,a |
R3220 |
T4753 |
T4752 |
arg1Of |
difference,significant |
R3221 |
T4753 |
T4754 |
arg1Of |
difference,in |
R3222 |
T4753 |
T4757 |
arg1Of |
difference,between |
R3223 |
T4756 |
T4754 |
arg2Of |
rates,in |
R3224 |
T4756 |
T4755 |
arg1Of |
rates,survival |
R3225 |
T4759 |
T4758 |
arg1Of |
mice,CCR5−/− |
R3226 |
T4759 |
T4760 |
arg1Of |
mice,and |
R3227 |
T4760 |
T4757 |
arg2Of |
and,between |
R3228 |
T4762 |
T4760 |
arg2Of |
mice,and |
R3229 |
T4762 |
T4761 |
arg1Of |
mice,CCR5+/+ |
R3230 |
T4765 |
T4763 |
arg2Of |
end,At |
R3231 |
T4765 |
T4764 |
arg1Of |
end,the |
R3232 |
T4765 |
T4766 |
arg1Of |
end,of |
R3233 |
T4768 |
T4766 |
arg2Of |
experiment,of |
R3234 |
T4768 |
T4767 |
arg1Of |
experiment,the |
R3235 |
T4771 |
T4770 |
arg1Of |
%,75 |
R3236 |
T4771 |
T4772 |
arg1Of |
%,of |
R3237 |
T4771 |
T4776 |
arg1Of |
%,survived |
R3238 |
T4775 |
T4772 |
arg2Of |
mice,of |
R3239 |
T4775 |
T4773 |
arg1Of |
mice,the |
R3240 |
T4775 |
T4774 |
arg1Of |
mice,CCR5−/− |
R3241 |
T4776 |
T4763 |
arg1Of |
survived,At |
R3242 |
T4776 |
T4769 |
arg1Of |
survived,"," |
R3243 |
T4776 |
T4777 |
arg1Of |
survived,while |
R3244 |
T4779 |
T4778 |
arg1Of |
15,only |
R3245 |
T4780 |
T4779 |
arg1Of |
%,15 |
R3246 |
T4780 |
T4781 |
arg1Of |
%,of |
R3247 |
T4780 |
T4785 |
arg1Of |
%,survived |
R3248 |
T4784 |
T4781 |
arg2Of |
mice,of |
R3249 |
T4784 |
T4782 |
arg1Of |
mice,the |
R3250 |
T4784 |
T4783 |
arg1Of |
mice,CCR5+/+ |
R3251 |
T4785 |
T4777 |
arg2Of |
survived,while |
R3252 |
T4787 |
T4786 |
arg1Of |
tumors,Subcutaneous |
R3253 |
T4787 |
T4788 |
arg1Of |
tumors,were |
R3254 |
T4787 |
T4789 |
arg2Of |
tumors,harvested |
R3255 |
T4789 |
T4788 |
arg2Of |
harvested,were |
R3256 |
T4789 |
T4790 |
arg1Of |
harvested,from |
R3257 |
T4789 |
T4795 |
arg1Of |
harvested,days |
R3258 |
T4793 |
T4790 |
arg2Of |
mice,from |
R3259 |
T4793 |
T4791 |
arg1Of |
mice,the |
R3260 |
T4793 |
T4792 |
arg2Of |
mice,sacrificed |
R3261 |
T4795 |
T4794 |
arg1Of |
days,31 |
R3262 |
T4795 |
T4796 |
arg1Of |
days,after |
R3263 |
T4797 |
T4796 |
arg2Of |
inoculation,after |
R3264 |
T4800 |
T4798 |
arg1Of |
analysis,The |
R3265 |
T4800 |
T4799 |
arg1Of |
analysis,immunohistochemical |
R3266 |
T4800 |
T4801 |
arg1Of |
analysis,of |
R3267 |
T4800 |
T4804 |
arg1Of |
analysis,"," |
R3268 |
T4800 |
T4805 |
arg2Of |
analysis,stained |
R3269 |
T4800 |
T4816 |
arg1Of |
analysis,revealed |
R3270 |
T4803 |
T4801 |
arg2Of |
sections,of |
R3271 |
T4803 |
T4802 |
arg1Of |
sections,tumor |
R3272 |
T4805 |
T4806 |
arg1Of |
stained,with |
R3273 |
T4805 |
T4811 |
arg1Of |
stained,for |
R3274 |
T4806 |
T4810 |
arg1Of |
with,and |
R3275 |
T4809 |
T4806 |
arg2Of |
E,with |
R3276 |
T4809 |
T4807 |
arg1Of |
E,H |
R3277 |
T4809 |
T4808 |
arg1Of |
E,& |
R3278 |
T4811 |
T4810 |
arg2Of |
for,and |
R3279 |
T4814 |
T4811 |
arg2Of |
PCNA,for |
R3280 |
T4814 |
T4812 |
arg1Of |
PCNA,proliferation |
R3281 |
T4814 |
T4813 |
arg1Of |
PCNA,antigen |
R3282 |
T4816 |
T4815 |
arg1Of |
revealed,"," |
R3283 |
T4818 |
T4816 |
arg2Of |
inhibition,revealed |
R3284 |
T4818 |
T4817 |
arg1Of |
inhibition,greater |
R3285 |
T4818 |
T4819 |
arg1Of |
inhibition,of |
R3286 |
T4822 |
T4819 |
arg2Of |
growth,of |
R3287 |
T4822 |
T4820 |
arg1Of |
growth,tumor |
R3288 |
T4822 |
T4821 |
arg1Of |
growth,cell |
R3289 |
T4822 |
T4823 |
arg1Of |
growth,in |
R3290 |
T4825 |
T4823 |
arg2Of |
mice,in |
R3291 |
T4825 |
T4824 |
arg1Of |
mice,CCR5−/− |
R3292 |
T4828 |
T4826 |
arg1Of |
findings,The |
R3293 |
T4828 |
T4827 |
arg1Of |
findings,histologic |
R3294 |
T4828 |
T4829 |
arg1Of |
findings,after |
R3295 |
T4828 |
T4834 |
arg1Of |
findings,indicated |
R3296 |
T4833 |
T4829 |
arg2Of |
staining,after |
R3297 |
T4833 |
T4830 |
arg1Of |
staining,H |
R3298 |
T4833 |
T4831 |
arg1Of |
staining,& |
R3299 |
T4833 |
T4832 |
arg1Of |
staining,E |
R3300 |
T4838 |
T4836 |
arg1Of |
tissues,the |
R3301 |
T4838 |
T4837 |
arg1Of |
tissues,tumor |
R3302 |
T4838 |
T4839 |
arg1Of |
tissues,of |
R3303 |
T4838 |
T4844 |
arg1Of |
tissues,but |
R3304 |
T4842 |
T4839 |
arg2Of |
mice,of |
R3305 |
T4842 |
T4840 |
arg1Of |
mice,the |
R3306 |
T4842 |
T4841 |
arg1Of |
mice,CCR5−/− |
R3307 |
T4844 |
T4843 |
arg1Of |
but,"," |
R3308 |
T4844 |
T4845 |
arg1Of |
but,not |
R3309 |
T4844 |
T4852 |
arg1Of |
but,contained |
R3310 |
T4846 |
T4844 |
arg2Of |
those,but |
R3311 |
T4846 |
T4847 |
arg1Of |
those,of |
R3312 |
T4850 |
T4847 |
arg2Of |
mice,of |
R3313 |
T4850 |
T4848 |
arg1Of |
mice,the |
R3314 |
T4850 |
T4849 |
arg1Of |
mice,CCR5+/+ |
R3315 |
T4852 |
T4834 |
arg2Of |
contained,indicated |
R3316 |
T4852 |
T4835 |
arg1Of |
contained,that |
R3317 |
T4852 |
T4851 |
arg1Of |
contained,"," |
R3318 |
T4854 |
T4852 |
arg2Of |
areas,contained |
R3319 |
T4854 |
T4853 |
arg1Of |
areas,large |
R3320 |
T4854 |
T4855 |
arg1Of |
areas,of |
R3321 |
T4856 |
T4855 |
arg2Of |
necrosis,of |
R3322 |
T4859 |
T4857 |
arg1Of |
cells,PCNA |
R3323 |
T4859 |
T4858 |
arg1Of |
cells,reactive |
R3324 |
T4859 |
T4860 |
arg1Of |
cells,were |
R3325 |
T4859 |
T4862 |
arg2Of |
cells,reduced |
R3326 |
T4862 |
T4860 |
arg2Of |
reduced,were |
R3327 |
T4862 |
T4861 |
arg1Of |
reduced,significantly |
R3328 |
T4862 |
T4863 |
arg1Of |
reduced,in |
R3329 |
T4866 |
T4863 |
arg2Of |
mice,in |
R3330 |
T4866 |
T4864 |
arg1Of |
mice,the |
R3331 |
T4866 |
T4865 |
arg1Of |
mice,CCR5−/− |
R3332 |
T4866 |
T4867 |
arg1Of |
mice,( |
R3333 |
T4869 |
T4867 |
arg2Of |
1E,( |
R3334 |
T4869 |
T4868 |
arg1Of |
1E,Figure |
R3335 |
T4870 |
T4867 |
arg3Of |
),( |
R3696 |
T5481 |
T5482 |
arg1Of |
Decrease,of |
R3697 |
T5481 |
T5485 |
arg1Of |
Decrease,in |
R3698 |
T5484 |
T5482 |
arg2Of |
Activity,of |
R3699 |
T5484 |
T5483 |
arg1Of |
Activity,NF-κB |
R3700 |
T5487 |
T5485 |
arg2Of |
Tissue,in |
R3701 |
T5487 |
T5486 |
arg1Of |
Tissue,Tumor |
R3702 |
T5487 |
T5488 |
arg1Of |
Tissue,of |
R3703 |
T5490 |
T5488 |
arg2Of |
Mice,of |
R3704 |
T5490 |
T5489 |
arg1Of |
Mice,CCR5−/− |
R3705 |
T5492 |
T5491 |
arg1Of |
activation,The |
R3706 |
T5492 |
T5493 |
arg1Of |
activation,of |
R3707 |
T5492 |
T5495 |
arg1Of |
activation,plays |
R3708 |
T5494 |
T5493 |
arg2Of |
NF-κB,of |
R3709 |
T5495 |
T5499 |
arg1Of |
plays,in |
R3710 |
T5495 |
T5509 |
arg1Of |
plays,in |
R3711 |
T5498 |
T5495 |
arg2Of |
role,plays |
R3712 |
T5498 |
T5496 |
arg1Of |
role,a |
R3713 |
T5498 |
T5497 |
arg1Of |
role,critical |
R3714 |
T5499 |
T5508 |
arg1Of |
in,and |
R3715 |
T5502 |
T5500 |
arg1Of |
survival,cancer |
R3716 |
T5502 |
T5501 |
arg1Of |
survival,cell |
R3717 |
T5502 |
T5503 |
arg1Of |
survival,"," |
R3718 |
T5503 |
T5499 |
arg2Of |
",",in |
R3719 |
T5507 |
T5503 |
arg2Of |
cells,"," |
R3720 |
T5507 |
T5504 |
arg1Of |
cells,especially |
R3721 |
T5507 |
T5505 |
arg1Of |
cells,melanoma |
R3722 |
T5507 |
T5506 |
arg1Of |
cells,cancer |
R3723 |
T5509 |
T5508 |
arg2Of |
in,and |
R3724 |
T5511 |
T5509 |
arg2Of |
expression,in |
R3725 |
T5511 |
T5510 |
arg1Of |
expression,CCR5 |
R3726 |
T5513 |
T5512 |
arg1Of |
evaluate,To |
R3727 |
T5517 |
T5515 |
arg1Of |
inhibition,the |
R3728 |
T5517 |
T5516 |
arg1Of |
inhibition,tumor |
R3729 |
T5517 |
T5518 |
arg1Of |
inhibition,was |
R3730 |
T5517 |
T5519 |
arg2Of |
inhibition,related |
R3731 |
T5519 |
T5513 |
arg2Of |
related,evaluate |
R3732 |
T5519 |
T5514 |
arg1Of |
related,whether |
R3733 |
T5519 |
T5518 |
arg2Of |
related,was |
R3734 |
T5519 |
T5520 |
arg1Of |
related,with |
R3735 |
T5522 |
T5520 |
arg2Of |
inactivation,with |
R3736 |
T5522 |
T5521 |
arg1Of |
inactivation,the |
R3737 |
T5522 |
T5523 |
arg1Of |
inactivation,of |
R3738 |
T5522 |
T5525 |
arg1Of |
inactivation,in |
R3739 |
T5524 |
T5523 |
arg2Of |
NF-κB,of |
R3740 |
T5526 |
T5525 |
arg2Of |
melanoma,in |
R3741 |
T5531 |
T5528 |
arg1Of |
activity,the |
R3742 |
T5531 |
T5529 |
arg1Of |
activity,DNA |
R3743 |
T5531 |
T5530 |
arg1Of |
activity,binding |
R3744 |
T5531 |
T5532 |
arg1Of |
activity,of |
R3745 |
T5531 |
T5534 |
arg1Of |
activity,was |
R3746 |
T5531 |
T5535 |
arg2Of |
activity,determined |
R3747 |
T5533 |
T5532 |
arg2Of |
NF-κB,of |
R3748 |
T5535 |
T5512 |
modOf |
determined,To |
R3749 |
T5535 |
T5527 |
arg1Of |
determined,"," |
R3750 |
T5535 |
T5534 |
arg2Of |
determined,was |
R3751 |
T5539 |
T5535 |
arg1Of |
assay,determined |
R3752 |
T5539 |
T5536 |
arg2Of |
assay,by |
R3753 |
T5539 |
T5537 |
arg1Of |
assay,electromobility |
R3754 |
T5539 |
T5538 |
arg1Of |
assay,shift |
R3755 |
T5539 |
T5540 |
arg1Of |
assay,( |
R3756 |
T5539 |
T5543 |
arg1Of |
assay,in |
R3757 |
T5541 |
T5540 |
arg2Of |
EMSA,( |
R3758 |
T5542 |
T5540 |
arg3Of |
),( |
R3759 |
T5545 |
T5543 |
arg2Of |
tissue,in |
R3760 |
T5545 |
T5544 |
arg1Of |
tissue,melanoma |
R3761 |
T5548 |
T5547 |
arg1Of |
activated,constitutively |
R3762 |
T5551 |
T5546 |
arg1Of |
activity,The |
R3763 |
T5551 |
T5548 |
arg1Of |
activity,activated |
R3764 |
T5551 |
T5549 |
arg1Of |
activity,DNA |
R3765 |
T5551 |
T5550 |
arg1Of |
activity,binding |
R3766 |
T5551 |
T5552 |
arg1Of |
activity,was |
R3767 |
T5551 |
T5553 |
arg2Of |
activity,reduced |
R3768 |
T5553 |
T5552 |
arg2Of |
reduced,was |
R3769 |
T5553 |
T5554 |
arg1Of |
reduced,in |
R3770 |
T5559 |
T5554 |
arg2Of |
tissue,in |
R3771 |
T5559 |
T5555 |
arg1Of |
tissue,the |
R3772 |
T5559 |
T5556 |
arg1Of |
tissue,CCR5−/− |
R3773 |
T5559 |
T5557 |
arg1Of |
tissue,mice |
R3774 |
T5559 |
T5558 |
arg1Of |
tissue,tumor |
R3775 |
T5559 |
T5560 |
arg1Of |
tissue,( |
R3776 |
T5562 |
T5560 |
arg2Of |
2A,( |
R3777 |
T5562 |
T5561 |
arg1Of |
2A,Figure |
R3778 |
T5563 |
T5560 |
arg3Of |
),( |
R3779 |
T5567 |
T5566 |
arg1Of |
translocation,the |
R3780 |
T5567 |
T5568 |
arg1Of |
translocation,of |
R3781 |
T5567 |
T5582 |
arg1Of |
translocation,was |
R3782 |
T5567 |
T5584 |
arg2Of |
translocation,prevented |
R3783 |
T5569 |
T5570 |
arg1Of |
p50,and |
R3784 |
T5570 |
T5568 |
arg2Of |
and,of |
R3785 |
T5570 |
T5572 |
arg1Of |
and,into |
R3786 |
T5570 |
T5575 |
arg1Of |
and,through |
R3787 |
T5571 |
T5570 |
arg2Of |
p-p65,and |
R3788 |
T5574 |
T5572 |
arg2Of |
nucleus,into |
R3789 |
T5574 |
T5573 |
arg1Of |
nucleus,the |
R3790 |
T5577 |
T5575 |
arg2Of |
inhibition,through |
R3791 |
T5577 |
T5576 |
arg1Of |
inhibition,the |
R3792 |
T5577 |
T5578 |
arg1Of |
inhibition,of |
R3793 |
T5579 |
T5578 |
arg2Of |
phosphorylation,of |
R3794 |
T5579 |
T5580 |
arg1Of |
phosphorylation,of |
R3795 |
T5581 |
T5580 |
arg2Of |
IκB,of |
R3796 |
T5584 |
T5564 |
arg1Of |
prevented,Moreover |
R3797 |
T5584 |
T5565 |
arg1Of |
prevented,"," |
R3798 |
T5584 |
T5582 |
arg2Of |
prevented,was |
R3799 |
T5584 |
T5583 |
arg1Of |
prevented,also |
R3800 |
T5584 |
T5585 |
arg1Of |
prevented,in |
R3801 |
T5588 |
T5585 |
arg2Of |
tissues,in |
R3802 |
T5588 |
T5586 |
arg1Of |
tissues,the |
R3803 |
T5588 |
T5587 |
arg1Of |
tissues,tumor |
R3804 |
T5588 |
T5589 |
arg1Of |
tissues,of |
R3805 |
T5591 |
T5589 |
arg2Of |
mice,of |
R3806 |
T5591 |
T5590 |
arg1Of |
mice,CCR5−/− |
R3807 |
T5591 |
T5592 |
arg1Of |
mice,( |
R3808 |
T5594 |
T5592 |
arg2Of |
2B,( |
R3809 |
T5594 |
T5593 |
arg1Of |
2B,Figure |
R3810 |
T5595 |
T5592 |
arg3Of |
),( |
R3811 |
T5597 |
T5596 |
arg1Of |
analysis,Immunofluorescence |
R3812 |
T5597 |
T5599 |
arg1Of |
analysis,confirmed |
R3813 |
T5599 |
T5598 |
arg1Of |
confirmed,also |
R3814 |
T5602 |
T5601 |
arg1Of |
intensity,the |
R3815 |
T5602 |
T5603 |
arg1Of |
intensity,of |
R3816 |
T5602 |
T5606 |
arg1Of |
intensity,for |
R3817 |
T5602 |
T5608 |
arg1Of |
intensity,had |
R3818 |
T5602 |
T5609 |
arg1Of |
intensity,decreased |
R3819 |
T5605 |
T5603 |
arg2Of |
staining,of |
R3820 |
T5605 |
T5604 |
arg1Of |
staining,nuclear |
R3821 |
T5607 |
T5606 |
arg2Of |
p50,for |
R3822 |
T5609 |
T5599 |
arg2Of |
decreased,confirmed |
R3823 |
T5609 |
T5600 |
arg1Of |
decreased,that |
R3824 |
T5609 |
T5608 |
arg2Of |
decreased,had |
R3825 |
T5609 |
T5610 |
arg1Of |
decreased,in |
R3826 |
T5613 |
T5610 |
arg2Of |
tissues,in |
R3827 |
T5613 |
T5611 |
arg1Of |
tissues,the |
R3828 |
T5613 |
T5612 |
arg1Of |
tissues,tumor |
R3829 |
T5613 |
T5614 |
arg1Of |
tissues,of |
R3830 |
T5616 |
T5614 |
arg2Of |
mice,of |
R3831 |
T5616 |
T5615 |
arg1Of |
mice,CCR5−/− |
R3832 |
T5616 |
T5617 |
arg1Of |
mice,( |
R3833 |
T5619 |
T5617 |
arg2Of |
2C,( |
R3834 |
T5619 |
T5618 |
arg1Of |
2C,Figure |
R3835 |
T5620 |
T5617 |
arg3Of |
),( |
R4059 |
T6030 |
T6031 |
arg1Of |
Induction,of |
R4060 |
T6030 |
T6035 |
arg1Of |
Induction,and |
R4061 |
T6034 |
T6031 |
arg2Of |
Death,of |
R4062 |
T6034 |
T6032 |
arg1Of |
Death,Apoptotic |
R4063 |
T6034 |
T6033 |
arg1Of |
Death,Cell |
R4064 |
T6036 |
T6035 |
arg2Of |
Inhibition,and |
R4065 |
T6036 |
T6037 |
arg1Of |
Inhibition,of |
R4066 |
T6039 |
T6037 |
arg2Of |
Expression,of |
R4067 |
T6039 |
T6038 |
arg1Of |
Expression,the |
R4068 |
T6039 |
T6040 |
arg1Of |
Expression,of |
R4069 |
T6039 |
T6043 |
arg1Of |
Expression,in |
R4070 |
T6042 |
T6040 |
arg2Of |
Proteins,of |
R4071 |
T6042 |
T6041 |
arg1Of |
Proteins,Anti-apoptotic |
R4072 |
T6045 |
T6043 |
arg2Of |
Mice,in |
R4073 |
T6045 |
T6044 |
arg1Of |
Mice,CCR5−/− |
R4074 |
T6047 |
T6046 |
arg1Of |
see,To |
R4075 |
T6049 |
T6050 |
arg1Of |
inhibition,of |
R4076 |
T6049 |
T6053 |
arg1Of |
inhibition,results |
R4077 |
T6052 |
T6050 |
arg2Of |
activity,of |
R4078 |
T6052 |
T6051 |
arg1Of |
activity,NF-κB |
R4079 |
T6053 |
T6047 |
arg2Of |
results,see |
R4080 |
T6053 |
T6048 |
arg1Of |
results,whether |
R4081 |
T6053 |
T6054 |
arg1Of |
results,in |
R4082 |
T6056 |
T6057 |
arg1Of |
induction,of |
R4083 |
T6056 |
T6061 |
arg1Of |
induction,and |
R4084 |
T6060 |
T6057 |
arg2Of |
death,of |
R4085 |
T6060 |
T6058 |
arg1Of |
death,apoptotic |
R4086 |
T6060 |
T6059 |
arg1Of |
death,cell |
R4087 |
T6061 |
T6054 |
arg2Of |
and,in |
R4088 |
T6061 |
T6055 |
arg1Of |
and,the |
R4089 |
T6062 |
T6061 |
arg2Of |
expression,and |
R4090 |
T6062 |
T6063 |
arg1Of |
expression,of |
R4091 |
T6070 |
T6063 |
arg2Of |
protein,of |
R4092 |
T6070 |
T6064 |
arg1Of |
protein,NF-κB |
R4093 |
T6070 |
T6065 |
arg1Of |
protein,target |
R4094 |
T6070 |
T6066 |
arg1Of |
protein,apoptotic |
R4095 |
T6070 |
T6067 |
arg1Of |
protein,cell |
R4096 |
T6070 |
T6068 |
arg1Of |
protein,death |
R4097 |
T6070 |
T6069 |
arg1Of |
protein,regulatory |
R4098 |
T6073 |
T6047 |
arg1Of |
levels,see |
R4099 |
T6073 |
T6072 |
arg1Of |
levels,the |
R4100 |
T6073 |
T6074 |
arg1Of |
levels,of |
R4101 |
T6073 |
T6086 |
arg1Of |
levels,were |
R4102 |
T6073 |
T6087 |
arg2Of |
levels,assessed |
R4103 |
T6077 |
T6075 |
arg1Of |
death,apoptotic |
R4104 |
T6077 |
T6076 |
arg1Of |
death,cell |
R4105 |
T6077 |
T6078 |
arg1Of |
death,and |
R4106 |
T6078 |
T6074 |
arg2Of |
and,of |
R4107 |
T6079 |
T6078 |
arg2Of |
expression,and |
R4108 |
T6079 |
T6080 |
arg1Of |
expression,of |
R4109 |
T6085 |
T6080 |
arg2Of |
proteins,of |
R4110 |
T6085 |
T6081 |
arg1Of |
proteins,apoptotic |
R4111 |
T6085 |
T6082 |
arg1Of |
proteins,cell |
R4112 |
T6085 |
T6083 |
arg1Of |
proteins,death |
R4113 |
T6085 |
T6084 |
arg1Of |
proteins,regulatory |
R4114 |
T6087 |
T6046 |
modOf |
assessed,To |
R4115 |
T6087 |
T6071 |
arg1Of |
assessed,"," |
R4116 |
T6087 |
T6086 |
arg2Of |
assessed,were |
R4117 |
T6090 |
T6088 |
arg1Of |
death,Apoptotic |
R4118 |
T6090 |
T6089 |
arg1Of |
death,cell |
R4119 |
T6090 |
T6091 |
arg1Of |
death,in |
R4120 |
T6090 |
T6095 |
arg1Of |
death,were |
R4121 |
T6090 |
T6096 |
arg2Of |
death,evaluated |
R4122 |
T6094 |
T6091 |
arg2Of |
sections,in |
R4123 |
T6094 |
T6092 |
arg1Of |
sections,the |
R4124 |
T6094 |
T6093 |
arg1Of |
sections,tumor |
R4125 |
T6096 |
T6095 |
arg2Of |
evaluated,were |
R4126 |
T6096 |
T6097 |
arg1Of |
evaluated,in |
R4127 |
T6099 |
T6100 |
arg1Of |
CCR5+/+,and |
R4128 |
T6101 |
T6100 |
arg2Of |
CCR5−/−,and |
R4129 |
T6102 |
T6097 |
arg2Of |
mice,in |
R4130 |
T6102 |
T6098 |
arg1Of |
mice,the |
R4131 |
T6102 |
T6099 |
arg1Of |
mice,CCR5+/+ |
R4132 |
T6102 |
T6101 |
arg1Of |
mice,CCR5−/− |
R4133 |
T6102 |
T6103 |
arg1Of |
mice,that |
R4134 |
T6102 |
T6104 |
arg1Of |
mice,were |
R4135 |
T6102 |
T6105 |
arg2Of |
mice,inoculated |
R4136 |
T6105 |
T6104 |
arg2Of |
inoculated,were |
R4137 |
T6105 |
T6106 |
arg1Of |
inoculated,with |
R4138 |
T6108 |
T6106 |
arg2Of |
cells,with |
R4139 |
T6108 |
T6107 |
arg1Of |
cells,melanoma |
R4140 |
T6110 |
T6109 |
arg1Of |
staining,TUNEL |
R4141 |
T6110 |
T6111 |
arg1Of |
staining,revealed |
R4142 |
T6114 |
T6111 |
arg2Of |
frequency,revealed |
R4143 |
T6114 |
T6112 |
arg1Of |
frequency,a |
R4144 |
T6114 |
T6113 |
arg1Of |
frequency,higher |
R4145 |
T6114 |
T6115 |
arg1Of |
frequency,of |
R4146 |
T6114 |
T6119 |
arg1Of |
frequency,in |
R4147 |
T6118 |
T6115 |
arg2Of |
death,of |
R4148 |
T6118 |
T6116 |
arg1Of |
death,apoptotic |
R4149 |
T6118 |
T6117 |
arg1Of |
death,cell |
R4150 |
T6122 |
T6119 |
arg2Of |
tissues,in |
R4151 |
T6122 |
T6120 |
arg1Of |
tissues,the |
R4152 |
T6122 |
T6121 |
arg1Of |
tissues,tumor |
R4153 |
T6122 |
T6123 |
arg1Of |
tissues,of |
R4154 |
T6122 |
T6127 |
arg1Of |
tissues,than |
R4155 |
T6126 |
T6123 |
arg2Of |
mice,of |
R4156 |
T6126 |
T6124 |
arg1Of |
mice,the |
R4157 |
T6126 |
T6125 |
arg1Of |
mice,CCR5−/− |
R4158 |
T6128 |
T6127 |
arg2Of |
that,than |
R4159 |
T6128 |
T6129 |
arg1Of |
that,of |
R4160 |
T6132 |
T6129 |
arg2Of |
mice,of |
R4161 |
T6132 |
T6130 |
arg1Of |
mice,the |
R4162 |
T6132 |
T6131 |
arg1Of |
mice,CCR5+/+ |
R4163 |
T6132 |
T6133 |
arg1Of |
mice,( |
R4164 |
T6135 |
T6133 |
arg2Of |
3A,( |
R4165 |
T6135 |
T6134 |
arg1Of |
3A,Figure |
R4166 |
T6136 |
T6133 |
arg3Of |
),( |
R4167 |
T6137 |
T6138 |
arg1Of |
Immunohistochemical,and |
R4168 |
T6138 |
T6140 |
arg1Of |
and,showed |
R4169 |
T6139 |
T6138 |
arg2Of |
immunofluorescence,and |
R4170 |
T6143 |
T6142 |
arg1Of |
levels,high |
R4171 |
T6143 |
T6144 |
arg1Of |
levels,of |
R4172 |
T6143 |
T6149 |
arg1Of |
levels,were |
R4173 |
T6143 |
T6150 |
arg2Of |
levels,found |
R4174 |
T6146 |
T6147 |
arg1Of |
caspase-3,and |
R4175 |
T6147 |
T6144 |
arg2Of |
and,of |
R4176 |
T6147 |
T6145 |
arg2Of |
and,cleaved |
R4177 |
T6148 |
T6147 |
arg2Of |
Bax,and |
R4178 |
T6150 |
T6140 |
arg2Of |
found,showed |
R4179 |
T6150 |
T6141 |
arg1Of |
found,that |
R4180 |
T6150 |
T6149 |
arg2Of |
found,were |
R4181 |
T6150 |
T6152 |
arg1Of |
found,frequently |
R4182 |
T6150 |
T6153 |
arg1Of |
found,in |
R4183 |
T6152 |
T6151 |
arg1Of |
frequently,more |
R4184 |
T6156 |
T6153 |
arg2Of |
mice,in |
R4185 |
T6156 |
T6154 |
arg1Of |
mice,the |
R4186 |
T6156 |
T6155 |
arg1Of |
mice,CCR5−/− |
R4187 |
T6156 |
T6157 |
arg1Of |
mice,than |
R4188 |
T6158 |
T6157 |
arg2Of |
in,than |
R4189 |
T6161 |
T6158 |
arg2Of |
mice,in |
R4190 |
T6161 |
T6159 |
arg1Of |
mice,the |
R4191 |
T6161 |
T6160 |
arg1Of |
mice,CCR5+/+ |
R4192 |
T6161 |
T6162 |
arg1Of |
mice,( |
R4193 |
T6164 |
T6163 |
arg1Of |
3B,Figure |
R4194 |
T6164 |
T6165 |
arg1Of |
3B,and |
R4195 |
T6165 |
T6162 |
arg2Of |
and,( |
R4196 |
T6166 |
T6165 |
arg2Of |
3C,and |
R4197 |
T6167 |
T6162 |
arg3Of |
),( |
R4198 |
T6168 |
T6169 |
arg1Of |
Consistent,with |
R4199 |
T6172 |
T6169 |
arg2Of |
data,with |
R4200 |
T6172 |
T6170 |
arg1Of |
data,the |
R4201 |
T6172 |
T6171 |
arg1Of |
data,immunohistochemical |
R4202 |
T6176 |
T6174 |
arg1Of |
analysis,Western |
R4203 |
T6176 |
T6175 |
arg1Of |
analysis,blot |
R4204 |
T6176 |
T6177 |
arg1Of |
analysis,of |
R4205 |
T6176 |
T6180 |
arg1Of |
analysis,showed |
R4206 |
T6179 |
T6177 |
arg2Of |
proteins,of |
R4207 |
T6179 |
T6178 |
arg1Of |
proteins,tumor |
R4208 |
T6180 |
T6168 |
arg1Of |
showed,Consistent |
R4209 |
T6180 |
T6173 |
arg1Of |
showed,"," |
R4210 |
T6183 |
T6180 |
arg2Of |
levels,showed |
R4211 |
T6183 |
T6181 |
arg1Of |
levels,greater |
R4212 |
T6183 |
T6182 |
arg2Of |
levels,increased |
R4213 |
T6183 |
T6184 |
arg1Of |
levels,of |
R4214 |
T6183 |
T6188 |
arg2Of |
levels,cleaved |
R4215 |
T6186 |
T6184 |
arg2Of |
caspase-3,of |
R4216 |
T6186 |
T6185 |
arg2Of |
caspase-3,cleaved |
R4217 |
T6188 |
T6187 |
arg1Of |
cleaved,"," |
R4218 |
T6189 |
T6188 |
arg3Of |
caspase-9,cleaved |
R4219 |
T6189 |
T6191 |
arg2Of |
caspase-9,cleaved |
R4220 |
T6191 |
T6190 |
arg1Of |
cleaved,"," |
R4221 |
T6191 |
T6195 |
arg1Of |
cleaved,"," |
R4222 |
T6191 |
T6196 |
arg1Of |
cleaved,whereas |
R4223 |
T6192 |
T6193 |
arg1Of |
PARP,and |
R4224 |
T6193 |
T6191 |
arg3Of |
and,cleaved |
R4225 |
T6194 |
T6193 |
arg2Of |
Bax,and |
R4226 |
T6198 |
T6197 |
arg1Of |
levels,the |
R4227 |
T6198 |
T6199 |
arg1Of |
levels,of |
R4228 |
T6198 |
T6203 |
arg1Of |
levels,were |
R4229 |
T6198 |
T6205 |
arg2Of |
levels,decreased |
R4230 |
T6200 |
T6201 |
arg1Of |
Bcl-2,and |
R4231 |
T6201 |
T6199 |
arg2Of |
and,of |
R4232 |
T6202 |
T6201 |
arg2Of |
C-IAP1,and |
R4233 |
T6205 |
T6196 |
arg2Of |
decreased,whereas |
R4234 |
T6205 |
T6203 |
arg2Of |
decreased,were |
R4235 |
T6205 |
T6204 |
arg1Of |
decreased,significantly |
R4236 |
T6205 |
T6206 |
arg1Of |
decreased,in |
R4237 |
T6209 |
T6206 |
arg2Of |
tissues,in |
R4238 |
T6209 |
T6207 |
arg1Of |
tissues,CCR5−/− |
R4239 |
T6209 |
T6208 |
arg1Of |
tissues,mice |
R4240 |
T6209 |
T6210 |
arg1Of |
tissues,( |
R4241 |
T6212 |
T6210 |
arg2Of |
3D,( |
R4242 |
T6212 |
T6211 |
arg1Of |
3D,Figure |
R4243 |
T6213 |
T6210 |
arg3Of |
),( |
R43 |
T260 |
T261 |
arg1Of |
Deficiency,of |
R44 |
T260 |
T266 |
arg1Of |
Deficiency,Suppresses |
R45 |
T264 |
T261 |
arg2Of |
Receptor,of |
R4504 |
T6715 |
T6716 |
arg1Of |
Upregulation,of |
R4505 |
T6715 |
T6718 |
arg1Of |
Upregulation,in |
R4506 |
T6717 |
T6716 |
arg2Of |
IL-1Ra,of |
R4507 |
T6720 |
T6721 |
arg1Of |
Tumor,and |
R4508 |
T6721 |
T6718 |
arg2Of |
and,in |
R4509 |
T6721 |
T6719 |
arg1Of |
and,the |
R4510 |
T6721 |
T6723 |
arg1Of |
and,of |
R4511 |
T6722 |
T6721 |
arg2Of |
Spleen,and |
R4512 |
T6725 |
T6723 |
arg2Of |
Mice,of |
R4513 |
T6725 |
T6724 |
arg1Of |
Mice,CCR5−/− |
R4514 |
T6727 |
T6726 |
arg1Of |
investigate,To |
R4515 |
T6729 |
T6727 |
arg2Of |
difference,investigate |
R4516 |
T6729 |
T6728 |
arg1Of |
difference,the |
R4517 |
T6729 |
T6730 |
arg1Of |
difference,in |
R4518 |
T6733 |
T6730 |
arg2Of |
levels,in |
R4519 |
T6733 |
T6731 |
arg1Of |
levels,the |
R4520 |
T6733 |
T6732 |
arg1Of |
levels,cytokine |
R4521 |
T6733 |
T6734 |
arg1Of |
levels,between |
R4522 |
T6736 |
T6737 |
arg1Of |
tumor,and |
R4523 |
T6738 |
T6737 |
arg2Of |
spleen,and |
R4524 |
T6739 |
T6734 |
arg2Of |
tissues,between |
R4525 |
T6739 |
T6735 |
arg1Of |
tissues,the |
R4526 |
T6739 |
T6736 |
arg1Of |
tissues,tumor |
R4527 |
T6739 |
T6738 |
arg1Of |
tissues,spleen |
R4528 |
T6739 |
T6740 |
arg1Of |
tissues,of |
R4529 |
T6742 |
T6743 |
arg1Of |
CCR5+/+,and |
R4530 |
T6744 |
T6743 |
arg2Of |
CCR5−/−,and |
R4531 |
T6745 |
T6740 |
arg2Of |
mice,of |
R4532 |
T6745 |
T6741 |
arg1Of |
mice,the |
R4533 |
T6745 |
T6742 |
arg1Of |
mice,CCR5+/+ |
R4534 |
T6745 |
T6744 |
arg1Of |
mice,CCR5−/− |
R4535 |
T6747 |
T6727 |
arg1Of |
we,investigate |
R4536 |
T6747 |
T6748 |
arg1Of |
we,conducted |
R4537 |
T6748 |
T6726 |
modOf |
conducted,To |
R4538 |
T6748 |
T6746 |
arg1Of |
conducted,"," |
R4539 |
T6752 |
T6748 |
arg2Of |
assay,conducted |
R4540 |
T6752 |
T6749 |
arg1Of |
assay,a |
R4541 |
T6752 |
T6750 |
arg1Of |
assay,cytokine |
R4542 |
T6752 |
T6751 |
arg1Of |
assay,array |
R4543 |
T6752 |
T6753 |
arg1Of |
assay,using |
R4544 |
T6757 |
T6753 |
arg2Of |
Array,using |
R4545 |
T6757 |
T6754 |
arg1Of |
Array,a |
R4546 |
T6757 |
T6755 |
arg1Of |
Array,Mouse |
R4547 |
T6757 |
T6756 |
arg1Of |
Array,Proteome |
R4548 |
T6757 |
T6758 |
arg1Of |
Array,( |
R4549 |
T6760 |
T6758 |
arg2Of |
4A,( |
R4550 |
T6760 |
T6759 |
arg1Of |
4A,Figure |
R4551 |
T6761 |
T6758 |
arg3Of |
),( |
R4552 |
T6765 |
T6762 |
arg2Of |
cytokines,Among |
R4553 |
T6765 |
T6763 |
arg1Of |
cytokines,40 |
R4554 |
T6765 |
T6764 |
arg2Of |
cytokines,tested |
R4555 |
T6768 |
T6767 |
arg1Of |
levels,the |
R4556 |
T6768 |
T6769 |
arg1Of |
levels,of |
R4557 |
T6768 |
T6775 |
arg1Of |
levels,increased |
R4558 |
T6770 |
T6771 |
arg1Of |
IL-1Ra,"," |
R4559 |
T6771 |
T6773 |
arg1Of |
",","," |
R4560 |
T6772 |
T6771 |
arg2Of |
MIG,"," |
R4561 |
T6773 |
T6769 |
arg2Of |
",",of |
R4562 |
T6774 |
T6773 |
arg2Of |
MIP-1α,"," |
R4563 |
T6775 |
T6762 |
arg1Of |
increased,Among |
R4564 |
T6775 |
T6766 |
arg1Of |
increased,"," |
R4565 |
T6775 |
T6783 |
arg1Of |
increased,"," |
R4566 |
T6775 |
T6784 |
arg1Of |
increased,in |
R4567 |
T6777 |
T6776 |
arg1Of |
686,about |
R4568 |
T6777 |
T6778 |
arg1Of |
686,"," |
R4569 |
T6778 |
T6775 |
arg2Of |
",",increased |
R4570 |
T6778 |
T6780 |
arg1Of |
",",and |
R4571 |
T6778 |
T6782 |
arg1Of |
",",respectively |
R4572 |
T6779 |
T6778 |
arg2Of |
9,"," |
R4573 |
T6782 |
T6781 |
arg1Of |
respectively,25-fold |
R4574 |
T6786 |
T6784 |
arg2Of |
mice,in |
R4575 |
T6786 |
T6785 |
arg1Of |
mice,CCR5−/− |
R4576 |
T6786 |
T6787 |
arg1Of |
mice,compared |
R4577 |
T6788 |
T6787 |
arg2Of |
to,compared |
R4578 |
T6790 |
T6788 |
arg2Of |
mice,to |
R4579 |
T6790 |
T6789 |
arg1Of |
mice,CCR5+/+ |
R4580 |
T6793 |
T6791 |
arg2Of |
technique,Using |
R4581 |
T6793 |
T6792 |
arg1Of |
technique,this |
R4582 |
T6797 |
T6791 |
arg1Of |
cytokines,Using |
R4583 |
T6797 |
T6795 |
arg1Of |
cytokines,no |
R4584 |
T6797 |
T6796 |
arg1Of |
cytokines,other |
R4585 |
T6797 |
T6798 |
arg1Of |
cytokines,were |
R4586 |
T6797 |
T6799 |
arg2Of |
cytokines,found |
R4587 |
T6797 |
T6801 |
arg1Of |
cytokines,be |
R4588 |
T6797 |
T6802 |
arg1Of |
cytokines,different |
R4589 |
T6799 |
T6791 |
modOf |
found,Using |
R4590 |
T6799 |
T6794 |
arg1Of |
found,"," |
R4591 |
T6799 |
T6798 |
arg2Of |
found,were |
R4592 |
T6801 |
T6799 |
arg3Of |
be,found |
R4593 |
T6801 |
T6800 |
arg1Of |
be,to |
R4594 |
T6802 |
T6801 |
arg2Of |
different,be |
R4595 |
T6802 |
T6803 |
arg1Of |
different,between |
R4596 |
T6806 |
T6804 |
arg1Of |
mice,the |
R4597 |
T6806 |
T6805 |
arg1Of |
mice,CCR5−/− |
R4598 |
T6806 |
T6807 |
arg1Of |
mice,and |
R4599 |
T6807 |
T6803 |
arg2Of |
and,between |
R46 |
T264 |
T262 |
arg1Of |
Receptor,C-C |
R4600 |
T6810 |
T6807 |
arg2Of |
mice,and |
R4601 |
T6810 |
T6808 |
arg1Of |
mice,the |
R4602 |
T6810 |
T6809 |
arg1Of |
mice,CCR5+/+ |
R4603 |
T6810 |
T6811 |
arg1Of |
mice,( |
R4604 |
T6813 |
T6811 |
arg2Of |
4B,( |
R4605 |
T6813 |
T6812 |
arg1Of |
4B,Figure |
R4606 |
T6814 |
T6811 |
arg3Of |
),( |
R4607 |
T6818 |
T6815 |
arg1Of |
levels,Similar |
R4608 |
T6818 |
T6816 |
arg1Of |
levels,altered |
R4609 |
T6818 |
T6817 |
arg1Of |
levels,cytokine |
R4610 |
T6818 |
T6819 |
arg1Of |
levels,were |
R4611 |
T6818 |
T6820 |
arg2Of |
levels,found |
R4612 |
T6820 |
T6819 |
arg2Of |
found,were |
R4613 |
T6820 |
T6821 |
arg1Of |
found,in |
R4614 |
T6823 |
T6821 |
arg2Of |
spleens,in |
R4615 |
T6823 |
T6822 |
arg1Of |
spleens,the |
R4616 |
T6823 |
T6824 |
arg1Of |
spleens,of |
R4617 |
T6826 |
T6824 |
arg2Of |
mice,of |
R4618 |
T6826 |
T6825 |
arg1Of |
mice,CCR5−/− |
R4619 |
T6826 |
T6827 |
arg1Of |
mice,( |
R4620 |
T6829 |
T6827 |
arg2Of |
4C,( |
R4621 |
T6829 |
T6828 |
arg1Of |
4C,Figure |
R4622 |
T6830 |
T6827 |
arg3Of |
),( |
R4623 |
T6834 |
T6832 |
arg1Of |
level,the |
R4624 |
T6834 |
T6833 |
arg1Of |
level,IL-1Ra |
R4625 |
T6834 |
T6835 |
arg1Of |
level,was |
R4626 |
T6834 |
T6839 |
arg2Of |
level,elevated |
R4627 |
T6838 |
T6837 |
arg1Of |
significantly,most |
R4628 |
T6839 |
T6831 |
arg2Of |
elevated,Since |
R4629 |
T6839 |
T6835 |
arg2Of |
elevated,was |
R4630 |
T6839 |
T6836 |
arg1Of |
elevated,the |
R4631 |
T6839 |
T6838 |
arg1Of |
elevated,significantly |
R4632 |
T6842 |
T6841 |
arg1Of |
expression,the |
R4633 |
T6842 |
T6843 |
arg1Of |
expression,of |
R4634 |
T6842 |
T6845 |
arg1Of |
expression,in |
R4635 |
T6842 |
T6850 |
arg1Of |
expression,was |
R4636 |
T6842 |
T6851 |
arg2Of |
expression,analyzed |
R4637 |
T6844 |
T6843 |
arg2Of |
IL-1Ra,of |
R4638 |
T6846 |
T6847 |
arg1Of |
tumor,and |
R4639 |
T6848 |
T6847 |
arg2Of |
spleen,and |
R4640 |
T6849 |
T6845 |
arg2Of |
tissues,in |
R4641 |
T6849 |
T6846 |
arg1Of |
tissues,tumor |
R4642 |
T6849 |
T6848 |
arg1Of |
tissues,spleen |
R4643 |
T6851 |
T6831 |
arg1Of |
analyzed,Since |
R4644 |
T6851 |
T6840 |
arg1Of |
analyzed,"," |
R4645 |
T6851 |
T6850 |
arg2Of |
analyzed,was |
R4646 |
T6853 |
T6854 |
arg1Of |
immunofluorescence,and |
R4647 |
T6855 |
T6854 |
arg2Of |
western,and |
R4648 |
T6856 |
T6851 |
arg1Of |
blotting,analyzed |
R4649 |
T6856 |
T6852 |
arg2Of |
blotting,by |
R4650 |
T6856 |
T6853 |
arg1Of |
blotting,immunofluorescence |
R4651 |
T6856 |
T6855 |
arg1Of |
blotting,western |
R4652 |
T6858 |
T6857 |
arg1Of |
expression,The |
R4653 |
T6858 |
T6859 |
arg1Of |
expression,of |
R4654 |
T6858 |
T6861 |
arg1Of |
expression,was |
R4655 |
T6858 |
T6862 |
arg2Of |
expression,upregulated |
R4656 |
T6860 |
T6859 |
arg2Of |
IL-1Ra,of |
R4657 |
T6862 |
T6861 |
arg2Of |
upregulated,was |
R4658 |
T6862 |
T6863 |
arg1Of |
upregulated,in |
R4659 |
T6864 |
T6865 |
arg1Of |
tumor,and |
R4660 |
T6866 |
T6865 |
arg2Of |
spleen,and |
R4661 |
T6867 |
T6863 |
arg2Of |
tissues,in |
R4662 |
T6867 |
T6864 |
arg1Of |
tissues,tumor |
R4663 |
T6867 |
T6866 |
arg1Of |
tissues,spleen |
R4664 |
T6867 |
T6868 |
arg1Of |
tissues,of |
R4665 |
T6871 |
T6868 |
arg2Of |
mice,of |
R4666 |
T6871 |
T6869 |
arg1Of |
mice,the |
R4667 |
T6871 |
T6870 |
arg1Of |
mice,CCR5−/− |
R4668 |
T6871 |
T6872 |
arg1Of |
mice,( |
R4669 |
T6874 |
T6872 |
arg2Of |
4D-G,( |
R4670 |
T6874 |
T6873 |
arg1Of |
4D-G,Figure |
R4671 |
T6875 |
T6872 |
arg3Of |
),( |
R47 |
T264 |
T263 |
arg1Of |
Receptor,Chemokine |
R48 |
T264 |
T265 |
arg1Of |
Receptor,5 |
R49 |
T268 |
T267 |
arg1Of |
Development via Inactivation,Tumor |
R4913 |
T7434 |
T7435 |
arg1Of |
Induction,of |
R4914 |
T7434 |
T7439 |
arg1Of |
Induction,and |
R4915 |
T7438 |
T7435 |
arg2Of |
cells,of |
R4916 |
T7438 |
T7436 |
arg1Of |
cells,CD8 |
R4917 |
T7438 |
T7437 |
arg1Of |
cells,T |
R4918 |
T7442 |
T7439 |
arg2Of |
Infiltration,and |
R4919 |
T7442 |
T7440 |
arg1Of |
Infiltration,NK |
R4920 |
T7442 |
T7441 |
arg1Of |
Infiltration,Cell |
R4921 |
T7442 |
T7443 |
arg1Of |
Infiltration,into |
R4922 |
T7444 |
T7445 |
arg1Of |
Tumor,and |
R4923 |
T7445 |
T7443 |
arg2Of |
and,into |
R4924 |
T7445 |
T7447 |
arg1Of |
and,of |
R4925 |
T7446 |
T7445 |
arg2Of |
Spleen,and |
R4926 |
T7449 |
T7447 |
arg2Of |
Mice,of |
R4927 |
T7449 |
T7448 |
arg1Of |
Mice,CCR5−/− |
R4928 |
T7451 |
T7450 |
arg1Of |
investigate,To |
R4929 |
T7454 |
T7453 |
arg1Of |
inhibition,the |
R4930 |
T7454 |
T7455 |
arg1Of |
inhibition,of |
R4931 |
T7454 |
T7461 |
arg1Of |
inhibition,is |
R4932 |
T7454 |
T7462 |
arg1Of |
inhibition,related |
R4933 |
T7457 |
T7455 |
arg2Of |
growth,of |
R4934 |
T7457 |
T7456 |
arg1Of |
growth,tumor |
R4935 |
T7457 |
T7458 |
arg1Of |
growth,in |
R4936 |
T7460 |
T7458 |
arg2Of |
mice,in |
R4937 |
T7460 |
T7459 |
arg1Of |
mice,CCR5−/− |
R4938 |
T7461 |
T7451 |
arg2Of |
is,investigate |
R4939 |
T7461 |
T7452 |
arg1Of |
is,whether |
R4940 |
T7462 |
T7461 |
arg2Of |
related,is |
R4941 |
T7462 |
T7463 |
arg1Of |
related,to |
R4942 |
T7466 |
T7463 |
arg2Of |
responses,to |
R4943 |
T7466 |
T7464 |
arg1Of |
responses,tumor-specific |
R4944 |
T7466 |
T7465 |
arg1Of |
responses,immune |
R4945 |
T7468 |
T7451 |
arg1Of |
we,investigate |
R4946 |
T7468 |
T7469 |
arg1Of |
we,analyzed |
R4947 |
T7469 |
T7450 |
modOf |
analyzed,To |
R4948 |
T7469 |
T7467 |
arg1Of |
analyzed,"," |
R4949 |
T7469 |
T7483 |
arg1Of |
analyzed,in |
R4950 |
T7472 |
T7469 |
arg2Of |
patterns,analyzed |
R4951 |
T7472 |
T7470 |
arg1Of |
patterns,the |
R4952 |
T7472 |
T7471 |
arg1Of |
patterns,distribution |
R4953 |
T7472 |
T7473 |
arg1Of |
patterns,of |
R4954 |
T7477 |
T7474 |
arg1Of |
cell,CD8+ |
R4955 |
T7477 |
T7475 |
arg1Of |
cell,cytotoxic |
R4956 |
T7477 |
T7476 |
arg1Of |
cell,T |
R4957 |
T7477 |
T7478 |
arg1Of |
cell,and |
R4958 |
T7478 |
T7473 |
arg2Of |
and,of |
R4959 |
T7482 |
T7478 |
arg2Of |
cells,and |
R4960 |
T7482 |
T7479 |
arg1Of |
cells,CD57+ |
R4961 |
T7482 |
T7480 |
arg1Of |
cells,Natural |
R4962 |
T7482 |
T7481 |
arg1Of |
cells,Killer |
R4963 |
T7484 |
T7485 |
arg1Of |
tumor,and |
R4964 |
T7486 |
T7485 |
arg2Of |
spleen,and |
R4965 |
T7487 |
T7483 |
arg2Of |
tissues,in |
R4966 |
T7487 |
T7484 |
arg1Of |
tissues,tumor |
R4967 |
T7487 |
T7486 |
arg1Of |
tissues,spleen |
R4968 |
T7489 |
T7488 |
arg2Of |
staining,By |
R4969 |
T7492 |
T7489 |
arg2Of |
sections,staining |
R4970 |
T7492 |
T7490 |
arg1Of |
sections,the |
R4971 |
T7492 |
T7491 |
arg1Of |
sections,tumor |
R4972 |
T7492 |
T7493 |
arg1Of |
sections,from |
R4973 |
T7495 |
T7493 |
arg2Of |
mice,from |
R4974 |
T7495 |
T7494 |
arg1Of |
mice,CCR5−/− |
R4975 |
T7497 |
T7489 |
arg1Of |
we,staining |
R4976 |
T7497 |
T7498 |
arg1Of |
we,found |
R4977 |
T7498 |
T7488 |
arg1Of |
found,By |
R4978 |
T7498 |
T7496 |
arg1Of |
found,"," |
R4979 |
T7500 |
T7501 |
arg1Of |
there,was |
R4980 |
T7501 |
T7498 |
arg2Of |
was,found |
R4981 |
T7501 |
T7499 |
arg1Of |
was,that |
R4982 |
T7504 |
T7502 |
arg1Of |
influx,a |
R4983 |
T7504 |
T7503 |
arg1Of |
influx,significant |
R4984 |
T7504 |
T7505 |
arg1Of |
influx,of |
R4985 |
T7504 |
T7508 |
arg1Of |
influx,into |
R4986 |
T7504 |
T7514 |
arg1Of |
influx,as |
R4987 |
T7507 |
T7505 |
arg2Of |
cells,of |
R4988 |
T7507 |
T7506 |
arg1Of |
cells,CD8+ |
R4989 |
T7510 |
T7508 |
arg2Of |
tumor,into |
R4990 |
T7510 |
T7509 |
arg1Of |
tumor,the |
R4991 |
T7514 |
T7501 |
arg2Of |
as,was |
R4992 |
T7514 |
T7511 |
arg1Of |
as,"," |
R4993 |
T7514 |
T7512 |
arg1Of |
as,as |
R4994 |
T7514 |
T7513 |
arg1Of |
as,well |
R4995 |
T7516 |
T7514 |
arg2Of |
increase,as |
R4996 |
T7516 |
T7515 |
arg1Of |
increase,an |
R4997 |
T7516 |
T7517 |
arg1Of |
increase,in |
R4998 |
T7519 |
T7517 |
arg2Of |
number,in |
R4999 |
T7519 |
T7518 |
arg1Of |
number,the |
R50 |
T268 |
T269 |
arg1Of |
Development via Inactivation,of |
R5000 |
T7519 |
T7520 |
arg1Of |
number,of |
R5001 |
T7523 |
T7520 |
arg2Of |
cells,of |
R5002 |
T7523 |
T7521 |
arg1Of |
cells,infiltrating |
R5003 |
T7523 |
T7522 |
arg1Of |
cells,NK |
R5004 |
T7523 |
T7524 |
arg1Of |
cells,( |
R5005 |
T7526 |
T7524 |
arg2Of |
5A,( |
R5006 |
T7526 |
T7525 |
arg1Of |
5A,Figure |
R5007 |
T7527 |
T7524 |
arg3Of |
),( |
R5008 |
T7530 |
T7528 |
arg1Of |
cells,CD8+ |
R5009 |
T7530 |
T7529 |
arg1Of |
cells,T |
R5010 |
T7530 |
T7531 |
arg1Of |
cells,and |
R5011 |
T7531 |
T7535 |
arg1Of |
and,were |
R5012 |
T7531 |
T7536 |
arg2Of |
and,spread |
R5013 |
T7534 |
T7531 |
arg2Of |
cells,and |
R5014 |
T7534 |
T7532 |
arg1Of |
cells,CD57+ |
R5015 |
T7534 |
T7533 |
arg1Of |
cells,NK |
R5016 |
T7536 |
T7535 |
arg2Of |
spread,were |
R5017 |
T7536 |
T7537 |
arg1Of |
spread,diffusely |
R5018 |
T7536 |
T7538 |
arg1Of |
spread,throughout |
R5019 |
T7541 |
T7538 |
arg2Of |
sections,throughout |
R5020 |
T7541 |
T7539 |
arg1Of |
sections,the |
R5021 |
T7541 |
T7540 |
arg1Of |
sections,entire |
R5022 |
T7544 |
T7542 |
arg1Of |
investigate,To |
R5023 |
T7544 |
T7543 |
arg1Of |
investigate,further |
R5024 |
T7546 |
T7544 |
arg2Of |
differences,investigate |
R5025 |
T7546 |
T7545 |
arg1Of |
differences,the |
R5026 |
T7546 |
T7547 |
arg1Of |
differences,in |
R5027 |
T7546 |
T7558 |
arg1Of |
differences,between |
R5028 |
T7549 |
T7547 |
arg2Of |
numbers,in |
R5029 |
T7549 |
T7548 |
arg1Of |
numbers,the |
R5030 |
T7549 |
T7550 |
arg1Of |
numbers,of |
R5031 |
T7553 |
T7551 |
arg1Of |
cells,CD8+ |
R5032 |
T7553 |
T7552 |
arg1Of |
cells,T |
R5033 |
T7553 |
T7554 |
arg1Of |
cells,and |
R5034 |
T7554 |
T7550 |
arg2Of |
and,of |
R5035 |
T7557 |
T7554 |
arg2Of |
cells,and |
R5036 |
T7557 |
T7555 |
arg1Of |
cells,CD57+ |
R5037 |
T7557 |
T7556 |
arg1Of |
cells,NK |
R5038 |
T7560 |
T7559 |
arg1Of |
mice,CCR5+/+ |
R5039 |
T7560 |
T7561 |
arg1Of |
mice,and |
R5040 |
T7561 |
T7558 |
arg2Of |
and,between |
R5041 |
T7561 |
T7564 |
arg1Of |
and,in |
R5042 |
T7563 |
T7561 |
arg2Of |
mice,and |
R5043 |
T7563 |
T7562 |
arg1Of |
mice,CCR5−/− |
R5044 |
T7566 |
T7564 |
arg2Of |
organ,in |
R5045 |
T7566 |
T7565 |
arg1Of |
organ,immunity-related |
R5046 |
T7568 |
T7544 |
arg1Of |
we,investigate |
R5047 |
T7568 |
T7570 |
arg1Of |
we,analyzed |
R5048 |
T7570 |
T7542 |
modOf |
analyzed,To |
R5049 |
T7570 |
T7567 |
arg1Of |
analyzed,"," |
R5050 |
T7570 |
T7569 |
arg1Of |
analyzed,also |
R5051 |
T7572 |
T7573 |
arg1Of |
CD8,and |
R5052 |
T7574 |
T7573 |
arg2Of |
CD57,and |
R5053 |
T7577 |
T7570 |
arg2Of |
number,analyzed |
R5054 |
T7577 |
T7571 |
arg1Of |
number,the |
R5055 |
T7577 |
T7572 |
arg1Of |
number,CD8 |
R5056 |
T7577 |
T7574 |
arg1Of |
number,CD57 |
R5057 |
T7577 |
T7575 |
arg1Of |
number,reactive |
R5058 |
T7577 |
T7576 |
arg1Of |
number,cell |
R5059 |
T7577 |
T7578 |
arg1Of |
number,in |
R5060 |
T7580 |
T7578 |
arg2Of |
tissues,in |
R5061 |
T7580 |
T7579 |
arg1Of |
tissues,spleen |
R5062 |
T7582 |
T7581 |
arg1Of |
number,The |
R5063 |
T7582 |
T7583 |
arg1Of |
number,of |
R5064 |
T7582 |
T7591 |
arg1Of |
number,were |
R5065 |
T7582 |
T7592 |
arg1Of |
number,higher |
R5066 |
T7586 |
T7584 |
arg1Of |
cells,CD8+ |
R5067 |
T7586 |
T7585 |
arg1Of |
cells,T |
R5068 |
T7586 |
T7587 |
arg1Of |
cells,and |
R5069 |
T7587 |
T7583 |
arg2Of |
and,of |
R5070 |
T7590 |
T7587 |
arg2Of |
cells,and |
R5071 |
T7590 |
T7588 |
arg1Of |
cells,CD57+ |
R5072 |
T7590 |
T7589 |
arg1Of |
cells,NK |
R5073 |
T7592 |
T7591 |
arg2Of |
higher,were |
R5074 |
T7592 |
T7593 |
arg1Of |
higher,in |
R5075 |
T7592 |
T7600 |
arg1Of |
higher,than |
R5076 |
T7595 |
T7593 |
arg2Of |
spleen,in |
R5077 |
T7595 |
T7594 |
arg1Of |
spleen,the |
R5078 |
T7595 |
T7596 |
arg1Of |
spleen,of |
R5079 |
T7599 |
T7596 |
arg2Of |
mice,of |
R5080 |
T7599 |
T7597 |
arg1Of |
mice,the |
R5081 |
T7599 |
T7598 |
arg1Of |
mice,CCR5−/− |
R5082 |
T7601 |
T7600 |
arg2Of |
in,than |
R5083 |
T7603 |
T7601 |
arg2Of |
spleen,in |
R5084 |
T7603 |
T7602 |
arg1Of |
spleen,the |
R5085 |
T7603 |
T7604 |
arg1Of |
spleen,of |
R5086 |
T7607 |
T7604 |
arg2Of |
mice,of |
R5087 |
T7607 |
T7605 |
arg1Of |
mice,the |
R5088 |
T7607 |
T7606 |
arg1Of |
mice,CCR5+/+ |
R5089 |
T7607 |
T7608 |
arg1Of |
mice,( |
R5090 |
T7610 |
T7608 |
arg2Of |
5B,( |
R5091 |
T7610 |
T7609 |
arg1Of |
5B,Figure |
R5092 |
T7611 |
T7608 |
arg3Of |
),( |
R5093 |
T7613 |
T7612 |
arg1Of |
data,These |
R5094 |
T7613 |
T7614 |
arg1Of |
data,suggest |
R5095 |
T7617 |
T7616 |
arg2Of |
promoting,by |
R5096 |
T7619 |
T7617 |
arg2Of |
infiltration,promoting |
R5097 |
T7619 |
T7618 |
arg1Of |
infiltration,the |
R5098 |
T7619 |
T7620 |
arg1Of |
infiltration,of |
R5099 |
T7623 |
T7621 |
arg1Of |
cells,CD8 |
R51 |
T268 |
T272 |
arg1Of |
Development via Inactivation,B a |
R5100 |
T7623 |
T7622 |
arg1Of |
cells,T |
R5101 |
T7623 |
T7624 |
arg1Of |
cells,and |
R5102 |
T7624 |
T7620 |
arg2Of |
and,of |
R5103 |
T7624 |
T7627 |
arg1Of |
and,"," |
R5104 |
T7624 |
T7628 |
arg1Of |
and,which |
R5105 |
T7624 |
T7629 |
arg1Of |
and,are |
R5106 |
T7626 |
T7624 |
arg2Of |
cells,and |
R5107 |
T7626 |
T7625 |
arg1Of |
cells,NK |
R5108 |
T7632 |
T7629 |
arg2Of |
effectors,are |
R5109 |
T7632 |
T7630 |
arg1Of |
effectors,potent |
R5110 |
T7632 |
T7631 |
arg1Of |
effectors,cytotoxic |
R5111 |
T7634 |
T7633 |
arg1Of |
tumors,for |
R5112 |
T7634 |
T7636 |
arg1Of |
tumors,could |
R5113 |
T7634 |
T7637 |
arg1Of |
tumors,play |
R5114 |
T7637 |
T7614 |
arg2Of |
play,suggest |
R5115 |
T7637 |
T7615 |
arg1Of |
play,that |
R5116 |
T7637 |
T7616 |
arg1Of |
play,by |
R5117 |
T7637 |
T7635 |
arg1Of |
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R5118 |
T7637 |
T7636 |
arg2Of |
play,could |
R5119 |
T7637 |
T7640 |
arg1Of |
play,in |
R5120 |
T7639 |
T7637 |
arg2Of |
role,play |
R5121 |
T7639 |
T7638 |
arg1Of |
role,a |
R5122 |
T7643 |
T7640 |
arg2Of |
effect,in |
R5123 |
T7643 |
T7641 |
arg1Of |
effect,an |
R5124 |
T7643 |
T7642 |
arg1Of |
effect,anti-tumor |
R5125 |
T7643 |
T7644 |
arg1Of |
effect,in |
R5126 |
T7646 |
T7644 |
arg2Of |
mice,in |
R5127 |
T7646 |
T7645 |
arg1Of |
mice,CCR5−/− |
R5128 |
T7648 |
T7647 |
arg1Of |
analyze,To |
R5129 |
T7648 |
T7659 |
arg1Of |
analyze,by |
R5130 |
T7652 |
T7648 |
arg2Of |
change,analyze |
R5131 |
T7652 |
T7649 |
arg1Of |
change,the |
R5132 |
T7652 |
T7650 |
arg1Of |
change,cell |
R5133 |
T7652 |
T7651 |
arg1Of |
change,phenotype |
R5134 |
T7652 |
T7653 |
arg1Of |
change,in |
R5135 |
T7655 |
T7654 |
arg1Of |
mice,CCR5−/− |
R5136 |
T7655 |
T7656 |
arg1Of |
mice,and |
R5137 |
T7656 |
T7653 |
arg2Of |
and,in |
R5138 |
T7658 |
T7656 |
arg2Of |
mice,and |
R5139 |
T7658 |
T7657 |
arg1Of |
mice,CCR5+/+ |
R5140 |
T7660 |
T7659 |
arg2Of |
inoculation,by |
R5141 |
T7660 |
T7661 |
arg1Of |
inoculation,of |
R5142 |
T7664 |
T7661 |
arg2Of |
cell,of |
R5143 |
T7664 |
T7662 |
arg1Of |
cell,the |
R5144 |
T7664 |
T7663 |
arg1Of |
cell,melanoma |
R5145 |
T7666 |
T7667 |
arg1Of |
lymphocytes,were |
R5146 |
T7666 |
T7668 |
arg2Of |
lymphocytes,isolated |
R5147 |
T7668 |
T7647 |
modOf |
isolated,To |
R5148 |
T7668 |
T7665 |
arg1Of |
isolated,"," |
R5149 |
T7668 |
T7667 |
arg2Of |
isolated,were |
R5150 |
T7668 |
T7669 |
arg1Of |
isolated,from |
R5151 |
T7671 |
T7672 |
arg1Of |
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R5152 |
T7673 |
T7672 |
arg2Of |
spleen,and |
R5153 |
T7674 |
T7669 |
arg2Of |
tissues,from |
R5154 |
T7674 |
T7670 |
arg1Of |
tissues,the |
R5155 |
T7674 |
T7671 |
arg1Of |
tissues,tumor |
R5156 |
T7674 |
T7673 |
arg1Of |
tissues,spleen |
R5157 |
T7676 |
T7675 |
arg1Of |
B,The |
R5158 |
T7676 |
T7677 |
arg1Of |
B,"," |
R5159 |
T7676 |
T7680 |
arg1Of |
B,"," |
R5160 |
T7676 |
T7683 |
arg1Of |
B,"," |
R5161 |
T7679 |
T7677 |
arg2Of |
T,"," |
R5162 |
T7679 |
T7678 |
arg1Of |
T,CD3 |
R5163 |
T7682 |
T7680 |
arg2Of |
T,"," |
R5164 |
T7682 |
T7681 |
arg1Of |
T,CD4 |
R5165 |
T7683 |
T7696 |
arg1Of |
",",were |
R5166 |
T7686 |
T7687 |
arg1Of |
T,and |
R5167 |
T7688 |
T7687 |
arg2Of |
NK,and |
R5168 |
T7690 |
T7683 |
arg2Of |
portion,"," |
R5169 |
T7690 |
T7684 |
arg1Of |
portion,CD |
R5170 |
T7690 |
T7685 |
arg1Of |
portion,8 |
R5171 |
T7690 |
T7686 |
arg1Of |
portion,T |
R5172 |
T7690 |
T7688 |
arg1Of |
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R5173 |
T7690 |
T7689 |
arg1Of |
portion,cell |
R5174 |
T7690 |
T7691 |
arg1Of |
portion,of |
R5175 |
T7695 |
T7691 |
arg2Of |
tissue,of |
R5176 |
T7695 |
T7692 |
arg1Of |
tissue,CCR5−/− |
R5177 |
T7695 |
T7693 |
arg1Of |
tissue,mice |
R5178 |
T7695 |
T7694 |
arg1Of |
tissue,tumor |
R5179 |
T7696 |
T7711 |
arg1Of |
were,"," |
R5180 |
T7696 |
T7712 |
arg1Of |
were,respectively |
R5181 |
T7696 |
T7713 |
arg1Of |
were,"," |
R5182 |
T7696 |
T7714 |
arg1Of |
were,compared |
R5183 |
T7698 |
T7697 |
arg1Of |
%,7.2 |
R5184 |
T7698 |
T7699 |
arg1Of |
%,"," |
R5185 |
T7699 |
T7702 |
arg1Of |
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R5186 |
T7701 |
T7699 |
arg2Of |
%,"," |
R5187 |
T7701 |
T7700 |
arg1Of |
%,48.2 |
R5188 |
T7702 |
T7705 |
arg1Of |
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R5189 |
T7704 |
T7702 |
arg2Of |
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R5190 |
T7704 |
T7703 |
arg1Of |
%,16.9 |
R5191 |
T7705 |
T7696 |
arg2Of |
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R5192 |
T7707 |
T7706 |
arg1Of |
%,32.1 |
R5193 |
T7707 |
T7708 |
arg1Of |
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R5194 |
T7709 |
T7708 |
arg2Of |
7.8,and |
R5195 |
T7710 |
T7705 |
arg2Of |
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R5196 |
T7710 |
T7707 |
arg1Of |
%,% |
R5197 |
T7710 |
T7709 |
arg1Of |
%,7.8 |
R5198 |
T7715 |
T7714 |
arg2Of |
to,compared |
R5199 |
T7717 |
T7716 |
arg1Of |
%,2.9 |
R52 |
T271 |
T269 |
arg2Of |
κ,of |
R5200 |
T7717 |
T7718 |
arg1Of |
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R5201 |
T7718 |
T7721 |
arg1Of |
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R5202 |
T7720 |
T7718 |
arg2Of |
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R5203 |
T7720 |
T7719 |
arg1Of |
%,11.1 |
R5204 |
T7721 |
T7724 |
arg1Of |
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R5205 |
T7723 |
T7721 |
arg2Of |
%,"," |
R5206 |
T7723 |
T7722 |
arg1Of |
%,2.3 |
R5207 |
T7724 |
T7727 |
arg1Of |
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R5208 |
T7726 |
T7724 |
arg2Of |
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R5209 |
T7726 |
T7725 |
arg1Of |
%,0.6 |
R5210 |
T7727 |
T7715 |
arg2Of |
and,to |
R5211 |
T7729 |
T7727 |
arg2Of |
%,and |
R5212 |
T7729 |
T7728 |
arg1Of |
%,3.1 |
R5213 |
T7729 |
T7730 |
arg1Of |
%,of |
R5214 |
T7732 |
T7730 |
arg2Of |
mice,of |
R5215 |
T7732 |
T7731 |
arg1Of |
mice,CCR5+/+ |
R5216 |
T7732 |
T7733 |
arg1Of |
mice,( |
R5217 |
T7735 |
T7733 |
arg2Of |
5C,( |
R5218 |
T7735 |
T7734 |
arg1Of |
5C,Figure |
R5219 |
T7736 |
T7733 |
arg3Of |
),( |
R5220 |
T7738 |
T7737 |
arg1Of |
lymphocytes,The |
R5221 |
T7738 |
T7739 |
arg1Of |
lymphocytes,that |
R5222 |
T7738 |
T7740 |
arg1Of |
lymphocytes,infiltrated |
R5223 |
T7738 |
T7749 |
arg1Of |
lymphocytes,had |
R5224 |
T7743 |
T7740 |
arg2Of |
tissue,infiltrated |
R5225 |
T7743 |
T7741 |
arg1Of |
tissue,the |
R5226 |
T7743 |
T7742 |
arg1Of |
tissue,tumor |
R5227 |
T7743 |
T7744 |
arg1Of |
tissue,of |
R5228 |
T7747 |
T7744 |
arg2Of |
mice,of |
R5229 |
T7747 |
T7745 |
arg1Of |
mice,the |
R5230 |
T7747 |
T7746 |
arg1Of |
mice,CCR5−/− |
R5231 |
T7749 |
T7748 |
arg1Of |
had,also |
R5232 |
T7749 |
T7762 |
arg1Of |
had,when |
R5233 |
T7751 |
T7749 |
arg2Of |
levels,had |
R5234 |
T7751 |
T7750 |
arg1Of |
levels,higher |
R5235 |
T7751 |
T7752 |
arg1Of |
levels,of |
R5236 |
T7753 |
T7754 |
arg1Of |
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R5237 |
T7754 |
T7756 |
arg1Of |
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R5238 |
T7755 |
T7754 |
arg2Of |
CD3,"," |
R5239 |
T7756 |
T7758 |
arg1Of |
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R5240 |
T7757 |
T7756 |
arg2Of |
CD4,"," |
R5241 |
T7758 |
T7760 |
arg1Of |
",",and |
R5242 |
T7759 |
T7758 |
arg2Of |
CD8,"," |
R5243 |
T7760 |
T7752 |
arg2Of |
and,of |
R5244 |
T7761 |
T7760 |
arg2Of |
CD57,and |
R5245 |
T7763 |
T7762 |
arg2Of |
compared,when |
R5246 |
T7763 |
T7764 |
arg1Of |
compared,to |
R5247 |
T7767 |
T7764 |
arg2Of |
mice,to |
R5248 |
T7767 |
T7765 |
arg1Of |
mice,the |
R5249 |
T7767 |
T7766 |
arg1Of |
mice,CCR5+/+ |
R5250 |
T7769 |
T7768 |
arg1Of |
B,The |
R5251 |
T7769 |
T7770 |
arg1Of |
B,"," |
R5252 |
T7769 |
T7773 |
arg1Of |
B,"," |
R5253 |
T7769 |
T7776 |
arg1Of |
B,"," |
R5254 |
T7772 |
T7770 |
arg2Of |
T,"," |
R5255 |
T7772 |
T7771 |
arg1Of |
T,CD3 |
R5256 |
T7775 |
T7773 |
arg2Of |
T,"," |
R5257 |
T7775 |
T7774 |
arg1Of |
T,CD4 |
R5258 |
T7776 |
T7789 |
arg1Of |
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R5259 |
T7779 |
T7780 |
arg1Of |
T,and |
R5260 |
T7781 |
T7780 |
arg2Of |
NK,and |
R5261 |
T7783 |
T7776 |
arg2Of |
portion,"," |
R5262 |
T7783 |
T7777 |
arg1Of |
portion,CD |
R5263 |
T7783 |
T7778 |
arg1Of |
portion,8 |
R5264 |
T7783 |
T7779 |
arg1Of |
portion,T |
R5265 |
T7783 |
T7781 |
arg1Of |
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R5266 |
T7783 |
T7782 |
arg1Of |
portion,cell |
R5267 |
T7783 |
T7784 |
arg1Of |
portion,of |
R5268 |
T7788 |
T7784 |
arg2Of |
spleen,of |
R5269 |
T7788 |
T7785 |
arg1Of |
spleen,the |
R5270 |
T7788 |
T7786 |
arg1Of |
spleen,CCR5−/− |
R5271 |
T7788 |
T7787 |
arg1Of |
spleen,mice |
R5272 |
T7789 |
T7806 |
arg1Of |
were,compared |
R5273 |
T7791 |
T7790 |
arg1Of |
%,61.3 |
R5274 |
T7791 |
T7792 |
arg1Of |
%,"," |
R5275 |
T7792 |
T7795 |
arg1Of |
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R5276 |
T7794 |
T7792 |
arg2Of |
%,"," |
R5277 |
T7794 |
T7793 |
arg1Of |
%,33.4 |
R5278 |
T7795 |
T7798 |
arg1Of |
",","," |
R5279 |
T7797 |
T7795 |
arg2Of |
%,"," |
R5280 |
T7797 |
T7796 |
arg1Of |
%,17.6 |
R5281 |
T7798 |
T7789 |
arg2Of |
",",were |
R5282 |
T7798 |
T7804 |
arg1Of |
",","," |
R5283 |
T7798 |
T7805 |
arg1Of |
",",respectively |
R5284 |
T7800 |
T7799 |
arg1Of |
%,9.2 |
R5285 |
T7800 |
T7801 |
arg1Of |
%,and |
R5286 |
T7802 |
T7801 |
arg2Of |
0.6,and |
R5287 |
T7803 |
T7798 |
arg2Of |
%,"," |
R5288 |
T7803 |
T7800 |
arg1Of |
%,% |
R5289 |
T7803 |
T7802 |
arg1Of |
%,0.6 |
R5290 |
T7807 |
T7806 |
arg2Of |
to,compared |
R5291 |
T7809 |
T7808 |
arg1Of |
%,38.3 |
R5292 |
T7809 |
T7810 |
arg1Of |
%,"," |
R5293 |
T7810 |
T7813 |
arg1Of |
",","," |
R5294 |
T7812 |
T7810 |
arg2Of |
%,"," |
R5295 |
T7812 |
T7811 |
arg1Of |
%,5.9 |
R5296 |
T7813 |
T7816 |
arg1Of |
",","," |
R5297 |
T7815 |
T7813 |
arg2Of |
%,"," |
R5298 |
T7815 |
T7814 |
arg1Of |
%,4.0 |
R5299 |
T7816 |
T7807 |
arg2Of |
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R53 |
T271 |
T270 |
arg1Of |
κ,NF- |
R5300 |
T7818 |
T7817 |
arg1Of |
%,1.0 |
R5301 |
T7818 |
T7819 |
arg1Of |
%,and |
R5302 |
T7820 |
T7819 |
arg2Of |
3.9,and |
R5303 |
T7821 |
T7816 |
arg2Of |
%,"," |
R5304 |
T7821 |
T7818 |
arg1Of |
%,% |
R5305 |
T7821 |
T7820 |
arg1Of |
%,3.9 |
R5306 |
T7821 |
T7822 |
arg1Of |
%,of |
R5307 |
T7825 |
T7822 |
arg2Of |
mice,of |
R5308 |
T7825 |
T7823 |
arg1Of |
mice,the |
R5309 |
T7825 |
T7824 |
arg1Of |
mice,CCR5+/+ |
R5310 |
T7825 |
T7826 |
arg1Of |
mice,( |
R5311 |
T7828 |
T7826 |
arg2Of |
5D,( |
R5312 |
T7828 |
T7827 |
arg1Of |
5D,Figure |
R5313 |
T7829 |
T7826 |
arg3Of |
),( |
R5314 |
T7831 |
T7830 |
arg1Of |
data,These |
R5315 |
T7831 |
T7832 |
arg1Of |
data,suggest |
R5316 |
T7835 |
T7834 |
arg2Of |
promoting,by |
R5317 |
T7837 |
T7835 |
arg2Of |
infiltration,promoting |
R5318 |
T7837 |
T7836 |
arg1Of |
infiltration,the |
R5319 |
T7837 |
T7838 |
arg1Of |
infiltration,of |
R5320 |
T7841 |
T7839 |
arg1Of |
cells,CD8 |
R5321 |
T7841 |
T7840 |
arg1Of |
cells,T |
R5322 |
T7841 |
T7842 |
arg1Of |
cells,and |
R5323 |
T7842 |
T7838 |
arg2Of |
and,of |
R5324 |
T7842 |
T7845 |
arg1Of |
and,"," |
R5325 |
T7842 |
T7846 |
arg1Of |
and,which |
R5326 |
T7842 |
T7847 |
arg1Of |
and,are |
R5327 |
T7844 |
T7842 |
arg2Of |
cells,and |
R5328 |
T7844 |
T7843 |
arg1Of |
cells,NK |
R5329 |
T7850 |
T7847 |
arg2Of |
effectors,are |
R5330 |
T7850 |
T7848 |
arg1Of |
effectors,potent |
R5331 |
T7850 |
T7849 |
arg1Of |
effectors,cytotoxic |
R5332 |
T7852 |
T7851 |
arg1Of |
tumors,for |
R5333 |
T7852 |
T7854 |
arg1Of |
tumors,could |
R5334 |
T7852 |
T7855 |
arg1Of |
tumors,play |
R5335 |
T7855 |
T7832 |
arg2Of |
play,suggest |
R5336 |
T7855 |
T7833 |
arg1Of |
play,that |
R5337 |
T7855 |
T7834 |
arg1Of |
play,by |
R5338 |
T7855 |
T7853 |
arg1Of |
play,"," |
R5339 |
T7855 |
T7854 |
arg2Of |
play,could |
R5340 |
T7855 |
T7858 |
arg1Of |
play,in |
R5341 |
T7857 |
T7855 |
arg2Of |
role,play |
R5342 |
T7857 |
T7856 |
arg1Of |
role,a |
R5343 |
T7860 |
T7858 |
arg2Of |
inhibition,in |
R5344 |
T7860 |
T7859 |
arg1Of |
inhibition,the |
R5345 |
T7860 |
T7861 |
arg1Of |
inhibition,of |
R5346 |
T7863 |
T7861 |
arg2Of |
growth,of |
R5347 |
T7863 |
T7862 |
arg1Of |
growth,tumor |
R5348 |
T7863 |
T7864 |
arg1Of |
growth,in |
R5349 |
T7866 |
T7864 |
arg2Of |
mice,in |
R5350 |
T7866 |
T7865 |
arg1Of |
mice,CCR5−/− |
R54 |
T272 |
T266 |
arg2Of |
B a,Suppresses |
R55 |
T273 |
T272 |
arg2Of |
nd Upregulat,B a |
R56 |
T273 |
T274 |
arg1Of |
nd Upregulat,io |
R57 |
T273 |
T276 |
arg1Of |
nd Upregulat,L- |
R58 |
T275 |
T274 |
arg2Of |
n of I,io |
R59 |
T278 |
T276 |
arg2Of |
elano,L- |
R5958 |
T9415 |
T9412 |
arg2Of |
study,In |
R5959 |
T9415 |
T9413 |
arg1Of |
study,the |
R5960 |
T9415 |
T9414 |
arg1Of |
study,present |
R5961 |
T9417 |
T9418 |
arg1Of |
we,found |
R5962 |
T9418 |
T9412 |
arg1Of |
found,In |
R5963 |
T9418 |
T9416 |
arg1Of |
found,"," |
R5964 |
T9421 |
T9420 |
arg1Of |
weight,tumor |
R5965 |
T9421 |
T9422 |
arg1Of |
weight,and |
R5966 |
T9422 |
T9424 |
arg1Of |
and,were |
R5967 |
T9422 |
T9426 |
arg1Of |
and,smaller |
R5968 |
T9423 |
T9422 |
arg2Of |
volume,and |
R5969 |
T9424 |
T9418 |
arg2Of |
were,found |
R5970 |
T9424 |
T9419 |
arg1Of |
were,that |
R5971 |
T9424 |
T9427 |
arg1Of |
were,in |
R5972 |
T9424 |
T9431 |
arg1Of |
were,compared |
R5973 |
T9426 |
T9424 |
arg2Of |
smaller,were |
R5974 |
T9426 |
T9425 |
arg1Of |
smaller,much |
R5975 |
T9430 |
T9427 |
arg2Of |
mice,in |
R5976 |
T9430 |
T9428 |
arg1Of |
mice,the |
R5977 |
T9430 |
T9429 |
arg1Of |
mice,CCR5−/− |
R5978 |
T9432 |
T9431 |
arg2Of |
to,compared |
R5979 |
T9435 |
T9432 |
arg2Of |
mice,to |
R5980 |
T9435 |
T9433 |
arg1Of |
mice,the |
R5981 |
T9435 |
T9434 |
arg1Of |
mice,CCR5+/+ |
R5982 |
T9435 |
T9436 |
arg2Of |
mice,inoculated |
R5983 |
T9436 |
T9437 |
arg1Of |
inoculated,with |
R5984 |
T9440 |
T9437 |
arg2Of |
cells,with |
R5985 |
T9440 |
T9438 |
arg1Of |
cells,B16 |
R5986 |
T9440 |
T9439 |
arg1Of |
cells,melanoma |
R5987 |
T9440 |
T9441 |
arg1Of |
cells,( |
R5988 |
T9443 |
T9442 |
arg1Of |
1A,Figure |
R5989 |
T9443 |
T9444 |
arg1Of |
1A,and |
R5990 |
T9444 |
T9441 |
arg2Of |
and,( |
R5991 |
T9445 |
T9444 |
arg2Of |
1B,and |
R5992 |
T9446 |
T9441 |
arg3Of |
),( |
R5993 |
T9450 |
T9447 |
arg1Of |
inhibition,The |
R5994 |
T9450 |
T9448 |
arg1Of |
inhibition,tumor |
R5995 |
T9450 |
T9449 |
arg1Of |
inhibition,growth |
R5996 |
T9450 |
T9451 |
arg1Of |
inhibition,in |
R5997 |
T9450 |
T9455 |
arg1Of |
inhibition,was |
R5998 |
T9450 |
T9456 |
arg2Of |
inhibition,associated |
R5999 |
T9454 |
T9451 |
arg2Of |
mice,in |
R60 |
T278 |
T277 |
arg1Of |
elano,1Ra in M |
R6000 |
T9454 |
T9452 |
arg1Of |
mice,the |
R6001 |
T9454 |
T9453 |
arg1Of |
mice,CCR5−/− |
R6002 |
T9456 |
T9455 |
arg2Of |
associated,was |
R6003 |
T9456 |
T9457 |
arg1Of |
associated,with |
R6004 |
T9459 |
T9457 |
arg2Of |
inhibition,with |
R6005 |
T9459 |
T9458 |
arg1Of |
inhibition,the |
R6006 |
T9459 |
T9460 |
arg1Of |
inhibition,of |
R6007 |
T9463 |
T9462 |
arg2Of |
NF-κB,activated |
R6008 |
T9463 |
T9464 |
arg1Of |
NF-κB,and |
R6009 |
T9464 |
T9460 |
arg2Of |
and,of |
R6010 |
T9464 |
T9461 |
arg1Of |
and,constitutively |
R6011 |
T9464 |
T9468 |
arg1Of |
and,in |
R6012 |
T9465 |
T9464 |
arg2Of |
elevation,and |
R6013 |
T9465 |
T9466 |
arg1Of |
elevation,of |
R6014 |
T9467 |
T9466 |
arg2Of |
IL-1Ra,of |
R6015 |
T9471 |
T9468 |
arg2Of |
tissue,in |
R6016 |
T9471 |
T9469 |
arg1Of |
tissue,the |
R6017 |
T9471 |
T9470 |
arg1Of |
tissue,tumor |
R6018 |
T9474 |
T9472 |
arg1Of |
activity,This |
R6019 |
T9474 |
T9473 |
arg1Of |
activity,anti-tumor |
R6020 |
T9474 |
T9475 |
arg1Of |
activity,was |
R6021 |
T9474 |
T9477 |
arg2Of |
activity,associated |
R6022 |
T9474 |
T9508 |
arg1Of |
activity,cleaved |
R6023 |
T9477 |
T9475 |
arg2Of |
associated,was |
R6024 |
T9477 |
T9476 |
arg1Of |
associated,also |
R6025 |
T9477 |
T9478 |
arg1Of |
associated,with |
R6026 |
T9477 |
T9499 |
arg1Of |
associated,with |
R6027 |
T9477 |
T9507 |
arg1Of |
associated,; |
R6028 |
T9478 |
T9498 |
arg1Of |
with,but |
R6029 |
T9480 |
T9479 |
arg2Of |
expression,decreased |
R6030 |
T9480 |
T9481 |
arg1Of |
expression,of |
R6031 |
T9480 |
T9489 |
arg1Of |
expression,and |
R6032 |
T9483 |
T9481 |
arg2Of |
target,of |
R6033 |
T9483 |
T9482 |
arg1Of |
target,NF-κB |
R6034 |
T9483 |
T9484 |
arg1Of |
target,anti-apoptotic |
R6035 |
T9483 |
T9487 |
arg1Of |
target,proliferative |
R6036 |
T9484 |
T9485 |
arg1Of |
anti-apoptotic,"," |
R6037 |
T9487 |
T9485 |
arg2Of |
proliferative,"," |
R6038 |
T9487 |
T9486 |
arg1Of |
proliferative,cell |
R6039 |
T9489 |
T9478 |
arg2Of |
and,with |
R6040 |
T9489 |
T9488 |
arg1Of |
and,"," |
R6041 |
T9490 |
T9489 |
arg2Of |
tumor,and |
R6042 |
T9490 |
T9491 |
arg1Of |
tumor,promoting |
R6043 |
T9492 |
T9491 |
arg2Of |
genes,promoting |
R6044 |
T9492 |
T9493 |
arg1Of |
genes,( |
R6045 |
T9494 |
T9495 |
arg1Of |
Bcl-2,and |
R6046 |
T9495 |
T9493 |
arg2Of |
and,( |
R6047 |
T9496 |
T9495 |
arg2Of |
C-IAP1,and |
R6048 |
T9497 |
T9493 |
arg3Of |
),( |
R6049 |
T9499 |
T9498 |
arg2Of |
with,but |
R6050 |
T9501 |
T9499 |
arg2Of |
expression,with |
R6051 |
T9501 |
T9500 |
arg2Of |
expression,increased |
R6052 |
T9501 |
T9502 |
arg1Of |
expression,of |
R6053 |
T9506 |
T9502 |
arg2Of |
genes,of |
R6054 |
T9506 |
T9503 |
arg1Of |
genes,their |
R6055 |
T9506 |
T9504 |
arg1Of |
genes,target |
R6056 |
T9506 |
T9505 |
arg1Of |
genes,apoptotic |
R6057 |
T9508 |
T9507 |
arg2Of |
cleaved,; |
R6058 |
T9509 |
T9510 |
arg1Of |
caspase-3,and |
R6059 |
T9510 |
T9513 |
arg1Of |
and,and |
R6060 |
T9511 |
T9510 |
arg2Of |
9,and |
R6061 |
T9513 |
T9508 |
arg2Of |
and,cleaved |
R6062 |
T9513 |
T9512 |
arg1Of |
and,"," |
R6063 |
T9514 |
T9513 |
arg2Of |
Bax,and |
R6064 |
T9514 |
T9515 |
arg1Of |
Bax,( |
R6065 |
T9517 |
T9515 |
arg2Of |
3A-D,( |
R6066 |
T9517 |
T9516 |
arg1Of |
3A-D,Figure |
R6067 |
T9518 |
T9515 |
arg3Of |
),( |
R6068 |
T9521 |
T9520 |
arg1Of |
tumor,the |
R6069 |
T9521 |
T9522 |
arg1Of |
tumor,and |
R6070 |
T9522 |
T9519 |
arg2Of |
and,In |
R6071 |
T9524 |
T9522 |
arg2Of |
spleen,and |
R6072 |
T9524 |
T9523 |
arg1Of |
spleen,the |
R6073 |
T9527 |
T9526 |
arg1Of |
number,the |
R6074 |
T9527 |
T9528 |
arg1Of |
number,of |
R6075 |
T9527 |
T9533 |
arg1Of |
number,"," |
R6076 |
T9532 |
T9528 |
arg2Of |
cells,of |
R6077 |
T9532 |
T9529 |
arg1Of |
cells,cytotoxic |
R6078 |
T9532 |
T9530 |
arg1Of |
cells,CD8+ |
R6079 |
T9532 |
T9531 |
arg1Of |
cells,T |
R6080 |
T9533 |
T9539 |
arg1Of |
",",and |
R6081 |
T9537 |
T9533 |
arg2Of |
cells,"," |
R6082 |
T9537 |
T9534 |
arg1Of |
cells,CD57+ |
R6083 |
T9537 |
T9535 |
arg1Of |
cells,natural |
R6084 |
T9537 |
T9536 |
arg1Of |
cells,killer |
R6085 |
T9539 |
T9538 |
arg1Of |
and,"," |
R6086 |
T9539 |
T9544 |
arg1Of |
and,were |
R6087 |
T9539 |
T9545 |
arg2Of |
and,increased |
R6088 |
T9541 |
T9539 |
arg2Of |
levels,and |
R6089 |
T9541 |
T9540 |
arg1Of |
levels,the |
R6090 |
T9541 |
T9542 |
arg1Of |
levels,of |
R6091 |
T9543 |
T9542 |
arg2Of |
IL-1Ra,of |
R6092 |
T9545 |
T9519 |
arg1Of |
increased,In |
R6093 |
T9545 |
T9525 |
arg1Of |
increased,"," |
R6094 |
T9545 |
T9544 |
arg2Of |
increased,were |
R6095 |
T9545 |
T9546 |
arg1Of |
increased,( |
R6096 |
T9547 |
T9548 |
arg1Of |
Figure,4 |
R6097 |
T9547 |
T9549 |
arg1Of |
Figure,and |
R6098 |
T9549 |
T9546 |
arg2Of |
and,( |
R6099 |
T9550 |
T9549 |
arg2Of |
5,and |
R61 |
T280 |
T279 |
arg1Of |
evaluate,To |
R6100 |
T9551 |
T9546 |
arg3Of |
),( |
R6101 |
T9553 |
T9552 |
arg1Of |
findings,These |
R6102 |
T9553 |
T9554 |
arg1Of |
findings,suggest |
R6103 |
T9557 |
T9556 |
arg1Of |
growth,melanoma |
R6104 |
T9557 |
T9558 |
arg1Of |
growth,was |
R6105 |
T9557 |
T9559 |
arg2Of |
growth,inhibited |
R6106 |
T9559 |
T9555 |
arg1Of |
inhibited,that |
R6107 |
T9559 |
T9558 |
arg2Of |
inhibited,was |
R6108 |
T9559 |
T9560 |
arg1Of |
inhibited,in |
R6109 |
T9559 |
T9565 |
arg1Of |
inhibited,and |
R6110 |
T9563 |
T9560 |
arg2Of |
mice,in |
R6111 |
T9563 |
T9561 |
arg1Of |
mice,the |
R6112 |
T9563 |
T9562 |
arg1Of |
mice,CCR5−/− |
R6113 |
T9565 |
T9554 |
arg2Of |
and,suggest |
R6114 |
T9565 |
T9564 |
arg1Of |
and,"," |
R6115 |
T9566 |
T9565 |
arg2Of |
that,and |
R6116 |
T9568 |
T9567 |
arg1Of |
elevation,the |
R6117 |
T9568 |
T9569 |
arg1Of |
elevation,of |
R6118 |
T9568 |
T9571 |
arg1Of |
elevation,"," |
R6119 |
T9568 |
T9572 |
arg2Of |
elevation,accompanied |
R6120 |
T9568 |
T9577 |
arg1Of |
elevation,is |
R6121 |
T9568 |
T9578 |
arg1Of |
elevation,significant |
R6122 |
T9570 |
T9569 |
arg2Of |
IL-1Ra,of |
R6123 |
T9572 |
T9573 |
arg1Of |
accompanied,with |
R6124 |
T9575 |
T9573 |
arg2Of |
NF-κB,with |
R6125 |
T9575 |
T9574 |
arg2Of |
NF-κB,decreased |
R6126 |
T9577 |
T9566 |
arg2Of |
is,that |
R6127 |
T9577 |
T9576 |
arg1Of |
is,"," |
R6128 |
T9578 |
T9577 |
arg2Of |
significant,is |
R6129 |
T9578 |
T9579 |
arg1Of |
significant,in |
R6130 |
T9581 |
T9579 |
arg2Of |
inhibition,in |
R6131 |
T9581 |
T9580 |
arg1Of |
inhibition,the |
R6132 |
T9581 |
T9582 |
arg1Of |
inhibition,of |
R6133 |
T9584 |
T9582 |
arg2Of |
growth,of |
R6134 |
T9584 |
T9583 |
arg1Of |
growth,melanoma |
R6135 |
T9584 |
T9585 |
arg1Of |
growth,in |
R6136 |
T9587 |
T9585 |
arg2Of |
mice,in |
R6137 |
T9587 |
T9586 |
arg1Of |
mice,CCR5−/− |
R6138 |
T9588 |
T9589 |
arg1Of |
NF-κB,regulates |
R6139 |
T9589 |
T9607 |
arg1Of |
regulates,[ |
R6140 |
T9591 |
T9589 |
arg2Of |
expression,regulates |
R6141 |
T9591 |
T9590 |
arg1Of |
expression,the |
R6142 |
T9591 |
T9592 |
arg1Of |
expression,of |
R6143 |
T9594 |
T9593 |
arg1Of |
200,over |
R6144 |
T9595 |
T9592 |
arg2Of |
genes,of |
R6145 |
T9595 |
T9594 |
arg1Of |
genes,200 |
R6146 |
T9595 |
T9596 |
arg1Of |
genes,that |
R6147 |
T9595 |
T9597 |
arg1Of |
genes,control |
R6148 |
T9600 |
T9599 |
arg1Of |
system,immune |
R6149 |
T9600 |
T9601 |
arg1Of |
system,"," |
R6150 |
T9601 |
T9605 |
arg1Of |
",",and |
R6151 |
T9604 |
T9601 |
arg2Of |
growth,"," |
R6152 |
T9604 |
T9602 |
arg1Of |
growth,cancer |
R6153 |
T9604 |
T9603 |
arg1Of |
growth,cell |
R6154 |
T9605 |
T9597 |
arg2Of |
and,control |
R6155 |
T9605 |
T9598 |
arg1Of |
and,the |
R6156 |
T9606 |
T9605 |
arg2Of |
inflammation,and |
R6157 |
T9608 |
T9607 |
arg2Of |
39,[ |
R6158 |
T9609 |
T9607 |
arg3Of |
],[ |
R6159 |
T9610 |
T9611 |
arg1Of |
Because,of |
R6160 |
T9613 |
T9610 |
arg2Of |
abilities,Because |
R6161 |
T9613 |
T9612 |
arg1Of |
abilities,its |
R6162 |
T9613 |
T9614 |
modOf |
abilities,to |
R6163 |
T9615 |
T9614 |
arg1Of |
induce,to |
R6164 |
T9617 |
T9615 |
arg2Of |
expression,induce |
R6165 |
T9617 |
T9616 |
arg1Of |
expression,the |
R6166 |
T9617 |
T9618 |
arg1Of |
expression,of |
R6167 |
T9617 |
T9628 |
arg1Of |
expression,as |
R6168 |
T9617 |
T9632 |
arg1Of |
expression,in |
R6169 |
T9621 |
T9618 |
arg2Of |
array,of |
R6170 |
T9621 |
T9619 |
arg1Of |
array,a |
R6171 |
T9621 |
T9620 |
arg1Of |
array,large |
R6172 |
T9621 |
T9622 |
arg1Of |
array,of |
R6173 |
T9624 |
T9623 |
arg1Of |
mediators,inflammatory |
R6174 |
T9624 |
T9625 |
arg1Of |
mediators,and |
R6175 |
T9625 |
T9622 |
arg2Of |
and,of |
R6176 |
T9627 |
T9625 |
arg2Of |
roles,and |
R6177 |
T9627 |
T9626 |
arg1Of |
roles,its |
R6178 |
T9631 |
T9628 |
arg2Of |
factors,as |
R6179 |
T9631 |
T9629 |
arg1Of |
factors,core |
R6180 |
T9631 |
T9630 |
arg1Of |
factors,transcription |
R6181 |
T9635 |
T9632 |
arg2Of |
responses,in |
R6182 |
T9635 |
T9633 |
arg1Of |
responses,diverse |
R6183 |
T9635 |
T9634 |
arg1Of |
responses,immune |
R6184 |
T9637 |
T9638 |
arg1Of |
NF-κB,has |
R6185 |
T9637 |
T9639 |
arg1Of |
NF-κB,been |
R6186 |
T9637 |
T9640 |
arg2Of |
NF-κB,recognized |
R6187 |
T9640 |
T9610 |
arg1Of |
recognized,Because |
R6188 |
T9640 |
T9636 |
arg1Of |
recognized,"," |
R6189 |
T9640 |
T9638 |
arg2Of |
recognized,has |
R6190 |
T9640 |
T9639 |
arg2Of |
recognized,been |
R6191 |
T9640 |
T9641 |
arg1Of |
recognized,as |
R6192 |
T9644 |
T9641 |
arg2Of |
factor,as |
R6193 |
T9644 |
T9642 |
arg1Of |
factor,a |
R6194 |
T9644 |
T9643 |
arg1Of |
factor,major |
R6195 |
T9644 |
T9645 |
arg1Of |
factor,responsible |
R6196 |
T9645 |
T9646 |
arg1Of |
responsible,for |
R6197 |
T9649 |
T9647 |
arg1Of |
development,cytokine-associated |
R6198 |
T9649 |
T9648 |
arg1Of |
development,cancer |
R6199 |
T9649 |
T9650 |
arg1Of |
development,or |
R62 |
T282 |
T280 |
arg2Of |
relevance,evaluate |
R6200 |
T9650 |
T9646 |
arg2Of |
or,for |
R6201 |
T9652 |
T9650 |
arg2Of |
immunity,or |
R6202 |
T9652 |
T9651 |
arg1Of |
immunity,anti-tumor |
R6203 |
T9657 |
T9653 |
arg2Of |
tissues,In |
R6204 |
T9657 |
T9654 |
arg1Of |
tissues,the |
R6205 |
T9657 |
T9655 |
arg1Of |
tissues,melanoma |
R6206 |
T9657 |
T9656 |
arg1Of |
tissues,tumor |
R6207 |
T9657 |
T9658 |
arg1Of |
tissues,of |
R6208 |
T9661 |
T9658 |
arg2Of |
mice,of |
R6209 |
T9661 |
T9659 |
arg1Of |
mice,the |
R6210 |
T9661 |
T9660 |
arg1Of |
mice,CCR5−/− |
R6211 |
T9664 |
T9663 |
arg1Of |
expression,the |
R6212 |
T9664 |
T9665 |
arg1Of |
expression,of |
R6213 |
T9664 |
T9686 |
arg1Of |
expression,were |
R6214 |
T9664 |
T9688 |
arg2Of |
expression,inhibited |
R6215 |
T9670 |
T9666 |
arg1Of |
genes,NF-κB |
R6216 |
T9670 |
T9667 |
arg1Of |
genes,target |
R6217 |
T9670 |
T9668 |
arg1Of |
genes,cell |
R6218 |
T9670 |
T9669 |
arg1Of |
genes,death |
R6219 |
T9670 |
T9671 |
arg1Of |
genes,( |
R6220 |
T9670 |
T9678 |
arg1Of |
genes,and |
R6221 |
T9672 |
T9673 |
arg1Of |
Bax,"," |
R6222 |
T9673 |
T9675 |
arg1Of |
",",and |
R6223 |
T9674 |
T9673 |
arg2Of |
caspase-3,"," |
R6224 |
T9675 |
T9671 |
arg2Of |
and,( |
R6225 |
T9676 |
T9675 |
arg2Of |
9,and |
R6226 |
T9677 |
T9671 |
arg3Of |
),( |
R6227 |
T9678 |
T9665 |
arg2Of |
and,of |
R6228 |
T9682 |
T9678 |
arg2Of |
activity,and |
R6229 |
T9682 |
T9679 |
arg1Of |
activity,the |
R6230 |
T9682 |
T9680 |
arg1Of |
activity,DNA |
R6231 |
T9682 |
T9681 |
arg1Of |
activity,binding |
R6232 |
T9682 |
T9683 |
arg1Of |
activity,of |
R6233 |
T9684 |
T9683 |
arg2Of |
NF-κB,of |
R6234 |
T9688 |
T9653 |
arg1Of |
inhibited,In |
R6235 |
T9688 |
T9662 |
arg1Of |
inhibited,"," |
R6236 |
T9688 |
T9685 |
arg1Of |
inhibited,"," |
R6237 |
T9688 |
T9686 |
arg2Of |
inhibited,were |
R6238 |
T9688 |
T9687 |
arg1Of |
inhibited,significantly |
R6239 |
T9688 |
T9690 |
arg1Of |
inhibited,but |
R6240 |
T9690 |
T9689 |
arg1Of |
but,"," |
R6241 |
T9692 |
T9691 |
arg1Of |
expression,the |
R6242 |
T9692 |
T9693 |
arg1Of |
expression,of |
R6243 |
T9692 |
T9706 |
arg1Of |
expression,were |
R6244 |
T9692 |
T9707 |
arg2Of |
expression,enhanced |
R6245 |
T9699 |
T9693 |
arg2Of |
genes,of |
R6246 |
T9699 |
T9694 |
arg1Of |
genes,cell |
R6247 |
T9699 |
T9695 |
arg1Of |
genes,death |
R6248 |
T9699 |
T9696 |
arg1Of |
genes,inhibitory |
R6249 |
T9699 |
T9697 |
arg1Of |
genes,NF-κB |
R6250 |
T9699 |
T9698 |
arg1Of |
genes,target |
R6251 |
T9699 |
T9700 |
arg1Of |
genes,"," |
R6252 |
T9699 |
T9702 |
arg1Of |
genes,as |
R6253 |
T9702 |
T9701 |
arg1Of |
as,such |
R6254 |
T9703 |
T9704 |
arg1Of |
Bcl-2,and |
R6255 |
T9704 |
T9702 |
arg2Of |
and,as |
R6256 |
T9705 |
T9704 |
arg2Of |
cIAP,and |
R6257 |
T9707 |
T9690 |
arg2Of |
enhanced,but |
R6258 |
T9707 |
T9706 |
arg2Of |
enhanced,were |
R6259 |
T9709 |
T9708 |
arg2Of |
addition,In |
R6260 |
T9711 |
T9712 |
arg1Of |
CCR5−/−,prevented |
R6261 |
T9712 |
T9708 |
arg1Of |
prevented,In |
R6262 |
T9712 |
T9710 |
arg1Of |
prevented,"," |
R6263 |
T9714 |
T9712 |
arg2Of |
phosphorylation,prevented |
R6264 |
T9714 |
T9713 |
arg1Of |
phosphorylation,the |
R6265 |
T9714 |
T9715 |
arg1Of |
phosphorylation,of |
R6266 |
T9714 |
T9717 |
arg1Of |
phosphorylation,"," |
R6267 |
T9714 |
T9718 |
arg2Of |
phosphorylation,accompanied |
R6268 |
T9714 |
T9731 |
arg1Of |
phosphorylation,( |
R6269 |
T9716 |
T9715 |
arg2Of |
IκB,of |
R6270 |
T9718 |
T9719 |
arg1Of |
accompanied,with |
R6271 |
T9721 |
T9719 |
arg2Of |
inhibition,with |
R6272 |
T9721 |
T9720 |
arg1Of |
inhibition,the |
R6273 |
T9721 |
T9722 |
arg1Of |
inhibition,of |
R6274 |
T9721 |
T9728 |
arg1Of |
inhibition,into |
R6275 |
T9724 |
T9725 |
arg1Of |
p50,and |
R6276 |
T9726 |
T9725 |
arg2Of |
p65,and |
R6277 |
T9727 |
T9722 |
arg2Of |
translocation,of |
R6278 |
T9727 |
T9723 |
arg1Of |
translocation,the |
R6279 |
T9727 |
T9724 |
arg1Of |
translocation,p50 |
R6280 |
T9727 |
T9726 |
arg1Of |
translocation,p65 |
R6281 |
T9730 |
T9728 |
arg2Of |
nucleus,into |
R6282 |
T9730 |
T9729 |
arg1Of |
nucleus,the |
R6283 |
T9733 |
T9731 |
arg2Of |
2A-C,( |
R6284 |
T9733 |
T9732 |
arg1Of |
2A-C,Figure |
R6285 |
T9734 |
T9731 |
arg3Of |
),( |
R6286 |
T9736 |
T9735 |
arg1Of |
tumors,Many |
R6287 |
T9736 |
T9737 |
arg1Of |
tumors,"," |
R6288 |
T9736 |
T9738 |
arg1Of |
tumors,including |
R6289 |
T9736 |
T9741 |
arg1Of |
tumors,have |
R6290 |
T9736 |
T9742 |
arg1Of |
tumors,increased |
R6291 |
T9739 |
T9738 |
arg2Of |
melanoma,including |
R6292 |
T9742 |
T9740 |
arg1Of |
increased,"," |
R6293 |
T9742 |
T9741 |
arg2Of |
increased,have |
R6294 |
T9743 |
T9742 |
arg2Of |
levels,increased |
R6295 |
T9743 |
T9744 |
arg1Of |
levels,of |
R6296 |
T9745 |
T9744 |
arg2Of |
NF-κB,of |
R6297 |
T9745 |
T9746 |
arg1Of |
NF-κB,[ |
R6298 |
T9745 |
T9749 |
arg1Of |
NF-κB,"," |
R6299 |
T9745 |
T9750 |
arg1Of |
NF-κB,which |
R63 |
T282 |
T281 |
arg1Of |
relevance,the |
R6300 |
T9745 |
T9751 |
arg1Of |
NF-κB,is |
R6301 |
T9745 |
T9753 |
arg1Of |
NF-κB,acting |
R6302 |
T9747 |
T9746 |
arg2Of |
40,[ |
R6303 |
T9748 |
T9746 |
arg3Of |
],[ |
R6304 |
T9753 |
T9751 |
arg2Of |
acting,is |
R6305 |
T9753 |
T9752 |
arg1Of |
acting,likely |
R6306 |
T9753 |
T9754 |
arg1Of |
acting,as |
R6307 |
T9757 |
T9754 |
arg2Of |
factor,as |
R6308 |
T9757 |
T9755 |
arg1Of |
factor,a |
R6309 |
T9757 |
T9756 |
arg1Of |
factor,survival |
R6310 |
T9757 |
T9758 |
arg1Of |
factor,for |
R6311 |
T9760 |
T9758 |
arg2Of |
growth,for |
R6312 |
T9760 |
T9759 |
arg1Of |
growth,melanoma |
R6313 |
T9764 |
T9763 |
arg1Of |
inhibitions,the |
R6314 |
T9764 |
T9765 |
arg1Of |
inhibitions,of |
R6315 |
T9764 |
T9768 |
arg1Of |
inhibitions,and |
R6316 |
T9767 |
T9765 |
arg2Of |
activity,of |
R6317 |
T9767 |
T9766 |
arg1Of |
activity,NF-κB |
R6318 |
T9768 |
T9774 |
arg1Of |
and,are |
R6319 |
T9768 |
T9775 |
arg1Of |
and,critical |
R6320 |
T9770 |
T9768 |
arg2Of |
expression,and |
R6321 |
T9770 |
T9769 |
arg1Of |
expression,the |
R6322 |
T9770 |
T9771 |
arg1Of |
expression,of |
R6323 |
T9773 |
T9771 |
arg2Of |
genes,of |
R6324 |
T9773 |
T9772 |
arg1Of |
genes,target |
R6325 |
T9774 |
T9761 |
arg1Of |
are,Thus |
R6326 |
T9774 |
T9762 |
arg1Of |
are,"," |
R6327 |
T9775 |
T9774 |
arg2Of |
critical,are |
R6328 |
T9775 |
T9776 |
arg1Of |
critical,in |
R6329 |
T9778 |
T9776 |
arg2Of |
inhibition,in |
R6330 |
T9778 |
T9777 |
arg1Of |
inhibition,the |
R6331 |
T9778 |
T9779 |
arg1Of |
inhibition,of |
R6332 |
T9781 |
T9779 |
arg2Of |
growth,of |
R6333 |
T9781 |
T9780 |
arg1Of |
growth,tumor |
R6334 |
T9781 |
T9782 |
arg1Of |
growth,in |
R6335 |
T9784 |
T9782 |
arg2Of |
mice,in |
R6336 |
T9784 |
T9783 |
arg1Of |
mice,CCR5−/− |
R6337 |
T9787 |
T9786 |
arg1Of |
mechanism,the |
R6338 |
T9787 |
T9788 |
arg1Of |
mechanism,is |
R6339 |
T9787 |
T9790 |
arg1Of |
mechanism,clear |
R6340 |
T9788 |
T9785 |
arg2Of |
is,Although |
R6341 |
T9788 |
T9789 |
arg1Of |
is,not |
R6342 |
T9790 |
T9788 |
arg2Of |
clear,is |
R6343 |
T9790 |
T9792 |
arg1Of |
clear,to |
R6344 |
T9792 |
T9791 |
arg1Of |
to,as |
R6345 |
T9793 |
T9792 |
arg2Of |
how,to |
R6346 |
T9794 |
T9795 |
arg1Of |
CCR5−/−,downregulates |
R6347 |
T9795 |
T9793 |
arg1Of |
downregulates,how |
R6348 |
T9796 |
T9795 |
arg2Of |
NF-κB,downregulates |
R6349 |
T9799 |
T9785 |
arg1Of |
is,Although |
R6350 |
T9799 |
T9797 |
arg1Of |
is,"," |
R6351 |
T9800 |
T9799 |
arg2Of |
noteworthy,is |
R6352 |
T9802 |
T9803 |
arg1Of |
NF-κB,is |
R6353 |
T9802 |
T9804 |
arg2Of |
NF-κB,activated |
R6354 |
T9802 |
T9806 |
arg2Of |
NF-κB,inactivated |
R6355 |
T9804 |
T9805 |
arg1Of |
activated,or |
R6356 |
T9805 |
T9798 |
arg1Of |
or,it |
R6357 |
T9805 |
T9799 |
arg1Of |
or,is |
R6358 |
T9805 |
T9800 |
arg1Of |
or,noteworthy |
R6359 |
T9805 |
T9801 |
arg1Of |
or,that |
R6360 |
T9805 |
T9803 |
arg2Of |
or,is |
R6361 |
T9806 |
T9805 |
arg2Of |
inactivated,or |
R6362 |
T9809 |
T9804 |
arg1Of |
cytokines,activated |
R6363 |
T9809 |
T9806 |
arg1Of |
cytokines,inactivated |
R6364 |
T9809 |
T9807 |
arg2Of |
cytokines,by |
R6365 |
T9809 |
T9808 |
arg1Of |
cytokines,many |
R6366 |
T9811 |
T9810 |
arg1Of |
studies,Numerous |
R6367 |
T9811 |
T9812 |
arg1Of |
studies,showed |
R6368 |
T9814 |
T9815 |
arg1Of |
cytokine,affect |
R6369 |
T9814 |
T9819 |
arg1Of |
cytokine,regulating |
R6370 |
T9815 |
T9812 |
arg2Of |
affect,showed |
R6371 |
T9815 |
T9813 |
arg1Of |
affect,that |
R6372 |
T9815 |
T9818 |
arg1Of |
affect,by |
R6373 |
T9817 |
T9815 |
arg2Of |
growth,affect |
R6374 |
T9817 |
T9816 |
arg1Of |
growth,tumor |
R6375 |
T9819 |
T9818 |
arg2Of |
regulating,by |
R6376 |
T9820 |
T9819 |
arg2Of |
NF-κB,regulating |
R6377 |
T9822 |
T9821 |
arg1Of |
cytokines,Inflammatory |
R6378 |
T9822 |
T9823 |
arg1Of |
cytokines,"," |
R6379 |
T9822 |
T9824 |
arg1Of |
cytokines,including |
R6380 |
T9822 |
T9831 |
arg1Of |
cytokines,activate |
R6381 |
T9825 |
T9826 |
arg1Of |
IL-1,"," |
R6382 |
T9826 |
T9828 |
arg1Of |
",",and |
R6383 |
T9827 |
T9826 |
arg2Of |
IL-6,"," |
R6384 |
T9828 |
T9824 |
arg2Of |
and,including |
R6385 |
T9829 |
T9828 |
arg2Of |
IL-8,and |
R6386 |
T9831 |
T9830 |
arg1Of |
activate,"," |
R6387 |
T9833 |
T9831 |
arg2Of |
pathways,activate |
R6388 |
T9833 |
T9832 |
arg1Of |
pathways,NF-κB |
R6389 |
T9833 |
T9834 |
arg1Of |
pathways,in |
R6390 |
T9836 |
T9834 |
arg2Of |
cells,in |
R6391 |
T9836 |
T9835 |
arg1Of |
cells,tumor |
R6392 |
T9836 |
T9837 |
arg1Of |
cells,[ |
R6393 |
T9838 |
T9837 |
arg2Of |
41,[ |
R6394 |
T9839 |
T9837 |
arg3Of |
],[ |
R6395 |
T9841 |
T9840 |
arg1Of |
interleukin,The |
R6396 |
T9841 |
T9842 |
arg1Of |
interleukin,10 |
R6397 |
T9841 |
T9843 |
arg1Of |
interleukin,( |
R6398 |
T9841 |
T9846 |
arg1Of |
interleukin,is |
R6399 |
T9841 |
T9848 |
arg2Of |
interleukin,known |
R64 |
T282 |
T283 |
arg1Of |
relevance,of |
R6400 |
T9844 |
T9843 |
arg2Of |
IL-10,( |
R6401 |
T9845 |
T9843 |
arg3Of |
),( |
R6402 |
T9848 |
T9846 |
arg2Of |
known,is |
R6403 |
T9848 |
T9847 |
arg1Of |
known,well |
R6404 |
T9848 |
T9849 |
arg1Of |
known,as |
R6405 |
T9848 |
T9862 |
arg1Of |
known,"," |
R6406 |
T9848 |
T9863 |
arg1Of |
known,[ |
R6407 |
T9852 |
T9850 |
arg1Of |
factor,an |
R6408 |
T9852 |
T9851 |
arg1Of |
factor,anti-tumor |
R6409 |
T9852 |
T9855 |
arg1Of |
factor,as |
R6410 |
T9855 |
T9849 |
arg2Of |
as,as |
R6411 |
T9855 |
T9853 |
arg1Of |
as,as |
R6412 |
T9855 |
T9854 |
arg1Of |
as,well |
R6413 |
T9858 |
T9855 |
arg2Of |
factor,as |
R6414 |
T9858 |
T9856 |
arg1Of |
factor,an |
R6415 |
T9858 |
T9857 |
arg1Of |
factor,anti-inflammatory |
R6416 |
T9858 |
T9859 |
arg1Of |
factor,[ |
R6417 |
T9860 |
T9859 |
arg2Of |
42,[ |
R6418 |
T9861 |
T9859 |
arg3Of |
],[ |
R6419 |
T9864 |
T9863 |
arg2Of |
43,[ |
R6420 |
T9865 |
T9863 |
arg3Of |
],[ |
R6421 |
T9866 |
T9867 |
arg1Of |
IL-10,inhibits |
R6422 |
T9867 |
T9868 |
arg1Of |
inhibits,constitutively |
R6423 |
T9867 |
T9880 |
arg1Of |
inhibits,[ |
R6424 |
T9870 |
T9867 |
arg2Of |
NF-κB,inhibits |
R6425 |
T9870 |
T9869 |
arg2Of |
NF-κB,activated |
R6426 |
T9870 |
T9873 |
arg1Of |
NF-κB,vitro |
R6427 |
T9870 |
T9874 |
arg1Of |
NF-κB,[ |
R6428 |
T9870 |
T9879 |
arg1Of |
NF-κB,vivo |
R6429 |
T9873 |
T9871 |
arg1Of |
vitro,both |
R6430 |
T9873 |
T9872 |
arg1Of |
vitro,in |
R6431 |
T9875 |
T9874 |
arg2Of |
44,[ |
R6432 |
T9876 |
T9874 |
arg3Of |
],[ |
R6433 |
T9879 |
T9877 |
arg1Of |
vivo,and |
R6434 |
T9879 |
T9878 |
arg1Of |
vivo,in |
R6435 |
T9881 |
T9880 |
arg2Of |
45,[ |
R6436 |
T9882 |
T9880 |
arg3Of |
],[ |
R6437 |
T9883 |
T9884 |
arg1Of |
Inhibition,of |
R6438 |
T9883 |
T9886 |
arg1Of |
Inhibition,by |
R6439 |
T9883 |
T9889 |
arg1Of |
Inhibition,contributes |
R6440 |
T9885 |
T9884 |
arg2Of |
NF-κB,of |
R6441 |
T9888 |
T9886 |
arg2Of |
IL-10,by |
R6442 |
T9888 |
T9887 |
arg1Of |
IL-10,the |
R6443 |
T9889 |
T9890 |
arg1Of |
contributes,to |
R6444 |
T9889 |
T9894 |
arg1Of |
contributes,through |
R6445 |
T9889 |
T9904 |
arg1Of |
contributes,[ |
R6446 |
T9893 |
T9890 |
arg2Of |
effects,to |
R6447 |
T9893 |
T9891 |
arg1Of |
effects,the |
R6448 |
T9893 |
T9892 |
arg1Of |
effects,anti-tumor |
R6449 |
T9896 |
T9894 |
arg2Of |
activation,through |
R6450 |
T9896 |
T9895 |
arg1Of |
activation,the |
R6451 |
T9896 |
T9897 |
arg1Of |
activation,of |
R6452 |
T9896 |
T9901 |
arg1Of |
activation,in |
R6453 |
T9898 |
T9899 |
arg1Of |
caspase-3,and |
R6454 |
T9899 |
T9897 |
arg2Of |
and,of |
R6455 |
T9900 |
T9899 |
arg2Of |
apoptosis,and |
R6456 |
T9903 |
T9901 |
arg2Of |
mice,in |
R6457 |
T9903 |
T9902 |
arg1Of |
mice,Colon26-bearing |
R6458 |
T9905 |
T9904 |
arg2Of |
43,[ |
R6459 |
T9906 |
T9904 |
arg3Of |
],[ |
R6460 |
T9910 |
T9909 |
arg1Of |
studies,several |
R6461 |
T9910 |
T9911 |
arg1Of |
studies,have |
R6462 |
T9910 |
T9912 |
arg1Of |
studies,demonstrated |
R6463 |
T9912 |
T9907 |
arg1Of |
demonstrated,Similarly |
R6464 |
T9912 |
T9908 |
arg1Of |
demonstrated,"," |
R6465 |
T9912 |
T9911 |
arg2Of |
demonstrated,have |
R6466 |
T9914 |
T9912 |
arg2Of |
ability,demonstrated |
R6467 |
T9914 |
T9913 |
arg1Of |
ability,the |
R6468 |
T9914 |
T9915 |
arg1Of |
ability,of |
R6469 |
T9914 |
T9917 |
modOf |
ability,to |
R6470 |
T9916 |
T9915 |
arg2Of |
IL-1Ra,of |
R6471 |
T9918 |
T9917 |
arg1Of |
abrogate,to |
R6472 |
T9921 |
T9918 |
arg2Of |
effects,abrogate |
R6473 |
T9921 |
T9919 |
arg1Of |
effects,the |
R6474 |
T9921 |
T9920 |
arg1Of |
effects,proinflammatory |
R6475 |
T9921 |
T9922 |
arg1Of |
effects,of |
R6476 |
T9923 |
T9922 |
arg2Of |
IL-1,of |
R6477 |
T9923 |
T9924 |
arg1Of |
IL-1,[ |
R6478 |
T9925 |
T9924 |
arg2Of |
46,[ |
R6479 |
T9926 |
T9924 |
arg3Of |
],[ |
R6480 |
T9927 |
T9928 |
arg1Of |
It,has |
R6481 |
T9927 |
T9929 |
arg1Of |
It,been |
R6482 |
T9927 |
T9930 |
arg2Of |
It,reported |
R6483 |
T9930 |
T9928 |
arg2Of |
reported,has |
R6484 |
T9930 |
T9929 |
arg2Of |
reported,been |
R6485 |
T9932 |
T9933 |
arg1Of |
IL-1,induces |
R6486 |
T9932 |
T9943 |
arg1Of |
IL-1,increases |
R6487 |
T9933 |
T9938 |
arg1Of |
induces,in |
R6488 |
T9933 |
T9942 |
arg1Of |
induces,and |
R6489 |
T9935 |
T9933 |
arg2Of |
activation,induces |
R6490 |
T9935 |
T9934 |
arg1Of |
activation,the |
R6491 |
T9935 |
T9936 |
arg1Of |
activation,of |
R6492 |
T9937 |
T9936 |
arg2Of |
NF-κB,of |
R6493 |
T9940 |
T9938 |
arg2Of |
cancers,in |
R6494 |
T9940 |
T9939 |
arg1Of |
cancers,several |
R6495 |
T9942 |
T9930 |
arg3Of |
and,reported |
R6496 |
T9942 |
T9931 |
arg1Of |
and,that |
R6497 |
T9942 |
T9941 |
arg1Of |
and,"," |
R6498 |
T9943 |
T9942 |
arg2Of |
increases,and |
R6499 |
T9946 |
T9944 |
arg1Of |
progression,cell |
R65 |
T290 |
T289 |
arg2Of |
CCR5,( |
R6500 |
T9946 |
T9945 |
arg1Of |
progression,cycle |
R6501 |
T9946 |
T9948 |
arg1Of |
progression,and |
R6502 |
T9948 |
T9943 |
arg2Of |
and,increases |
R6503 |
T9948 |
T9947 |
arg1Of |
and,"," |
R6504 |
T9950 |
T9948 |
arg2Of |
suppression,and |
R6505 |
T9950 |
T9949 |
arg1Of |
suppression,the |
R6506 |
T9950 |
T9951 |
arg1Of |
suppression,of |
R6507 |
T9950 |
T9955 |
arg1Of |
suppression,leading |
R6508 |
T9954 |
T9951 |
arg2Of |
death,of |
R6509 |
T9954 |
T9952 |
arg1Of |
death,apoptotic |
R6510 |
T9954 |
T9953 |
arg1Of |
death,cell |
R6511 |
T9955 |
T9956 |
arg1Of |
leading,to |
R6512 |
T9958 |
T9956 |
arg2Of |
promotion,to |
R6513 |
T9958 |
T9957 |
arg1Of |
promotion,tumor |
R6514 |
T9960 |
T9959 |
arg1Of |
results,The |
R6515 |
T9960 |
T9961 |
arg1Of |
results,of |
R6516 |
T9960 |
T9964 |
arg1Of |
results,over |
R6517 |
T9960 |
T9969 |
arg1Of |
results,indicate |
R6518 |
T9963 |
T9961 |
arg2Of |
studies,of |
R6519 |
T9963 |
T9962 |
arg1Of |
studies,various |
R6520 |
T9968 |
T9964 |
arg2Of |
years,over |
R6521 |
T9968 |
T9965 |
arg1Of |
years,the |
R6522 |
T9968 |
T9966 |
arg1Of |
years,past |
R6523 |
T9968 |
T9967 |
arg1Of |
years,10 |
R6524 |
T9973 |
T9971 |
arg1Of |
function,the |
R6525 |
T9973 |
T9972 |
arg1Of |
function,major |
R6526 |
T9973 |
T9974 |
arg1Of |
function,of |
R6527 |
T9973 |
T9976 |
arg1Of |
function,is |
R6528 |
T9975 |
T9974 |
arg2Of |
IL-1Ra,of |
R6529 |
T9976 |
T9969 |
arg2Of |
is,indicate |
R6530 |
T9976 |
T9970 |
arg1Of |
is,that |
R6531 |
T9978 |
T9976 |
arg2Of |
regulate,is |
R6532 |
T9978 |
T9977 |
arg1Of |
regulate,to |
R6533 |
T9978 |
T9984 |
arg1Of |
regulate,by |
R6534 |
T9981 |
T9978 |
arg2Of |
effects,regulate |
R6535 |
T9981 |
T9979 |
arg1Of |
effects,the |
R6536 |
T9981 |
T9980 |
arg1Of |
effects,pleiotropic |
R6537 |
T9981 |
T9982 |
arg1Of |
effects,of |
R6538 |
T9983 |
T9982 |
arg2Of |
IL-1,of |
R6539 |
T9986 |
T9984 |
arg2Of |
blocking,by |
R6540 |
T9986 |
T9985 |
arg1Of |
blocking,competitively |
R6541 |
T9988 |
T9986 |
arg2Of |
functions,blocking |
R6542 |
T9988 |
T9987 |
arg1Of |
functions,its |
R6543 |
T9988 |
T9989 |
arg1Of |
functions,[ |
R6544 |
T9990 |
T9989 |
arg2Of |
47,[ |
R6545 |
T9991 |
T9989 |
arg3Of |
],[ |
R6546 |
T9993 |
T9992 |
arg1Of |
ability,The |
R6547 |
T9993 |
T9994 |
arg1Of |
ability,of |
R6548 |
T9993 |
T9996 |
modOf |
ability,to |
R6549 |
T9993 |
T10001 |
arg1Of |
ability,is |
R6550 |
T9993 |
T10002 |
arg1Of |
ability,of |
R6551 |
T9995 |
T9994 |
arg2Of |
IL-1,of |
R6552 |
T9997 |
T9996 |
arg1Of |
induce,to |
R6553 |
T10000 |
T9997 |
arg2Of |
antagonist,induce |
R6554 |
T10000 |
T9998 |
arg1Of |
antagonist,its |
R6555 |
T10000 |
T9999 |
arg1Of |
antagonist,own |
R6556 |
T10002 |
T10001 |
arg2Of |
of,is |
R6557 |
T10003 |
T10002 |
arg2Of |
interest,of |
R6558 |
T10003 |
T10004 |
arg1Of |
interest,in |
R6559 |
T10005 |
T10004 |
arg2Of |
understanding,in |
R6560 |
T10007 |
T10008 |
arg1Of |
regulation,and |
R6561 |
T10008 |
T10005 |
arg2Of |
and,understanding |
R6562 |
T10008 |
T10006 |
arg1Of |
and,the |
R6563 |
T10008 |
T10010 |
arg1Of |
and,of |
R6564 |
T10008 |
T10013 |
arg1Of |
and,in |
R6565 |
T10009 |
T10008 |
arg2Of |
dysregulation,and |
R6566 |
T10012 |
T10010 |
arg2Of |
signaling,of |
R6567 |
T10012 |
T10011 |
arg1Of |
signaling,IL-1 |
R6568 |
T10014 |
T10015 |
arg1Of |
normal,and |
R6569 |
T10016 |
T10015 |
arg2Of |
diseased,and |
R6570 |
T10017 |
T10013 |
arg2Of |
tissue,in |
R6571 |
T10017 |
T10014 |
arg1Of |
tissue,normal |
R6572 |
T10017 |
T10016 |
arg1Of |
tissue,diseased |
R6573 |
T10018 |
T10019 |
arg1Of |
Up-regulation,of |
R6574 |
T10018 |
T10023 |
arg1Of |
Up-regulation,represents |
R6575 |
T10022 |
T10019 |
arg2Of |
antagonist,of |
R6576 |
T10022 |
T10020 |
arg1Of |
antagonist,the |
R6577 |
T10022 |
T10021 |
arg1Of |
antagonist,receptor |
R6578 |
T10025 |
T10023 |
arg2Of |
mechanism,represents |
R6579 |
T10025 |
T10024 |
arg1Of |
mechanism,a |
R6580 |
T10025 |
T10026 |
arg1Of |
mechanism,for |
R6581 |
T10027 |
T10028 |
arg1Of |
turning,off |
R6582 |
T10027 |
T10031 |
arg1Of |
turning,and |
R6583 |
T10030 |
T10027 |
arg2Of |
signaling,turning |
R6584 |
T10030 |
T10029 |
arg1Of |
signaling,IL-1 |
R6585 |
T10031 |
T10026 |
arg2Of |
and,for |
R6586 |
T10032 |
T10031 |
arg2Of |
creating,and |
R6587 |
T10035 |
T10032 |
arg2Of |
state,creating |
R6588 |
T10035 |
T10033 |
arg1Of |
state,a |
R6589 |
T10035 |
T10034 |
arg1Of |
state,temporary |
R6590 |
T10035 |
T10036 |
arg1Of |
state,of |
R6591 |
T10037 |
T10036 |
arg2Of |
refractoriness,of |
R6592 |
T10040 |
T10038 |
arg1Of |
expression,The |
R6593 |
T10040 |
T10039 |
arg2Of |
expression,elevated |
R6594 |
T10040 |
T10041 |
arg1Of |
expression,of |
R6595 |
T10040 |
T10043 |
arg1Of |
expression,"," |
R6596 |
T10040 |
T10044 |
arg1Of |
expression,without |
R6597 |
T10040 |
T10052 |
arg1Of |
expression,suggests |
R6598 |
T10042 |
T10041 |
arg2Of |
IL-1Ra,of |
R6599 |
T10046 |
T10044 |
arg2Of |
change,without |
R66 |
T291 |
T289 |
arg3Of |
),( |
R6600 |
T10046 |
T10045 |
arg1Of |
change,any |
R6601 |
T10046 |
T10047 |
arg1Of |
change,of |
R6602 |
T10046 |
T10049 |
arg1Of |
change,in |
R6603 |
T10048 |
T10047 |
arg2Of |
IL-1,of |
R6604 |
T10050 |
T10049 |
arg2Of |
tumors,in |
R6605 |
T10052 |
T10051 |
arg1Of |
suggests,"," |
R6606 |
T10056 |
T10054 |
arg1Of |
system,the |
R6607 |
T10056 |
T10055 |
arg1Of |
system,IL-1-signaling |
R6608 |
T10056 |
T10057 |
arg1Of |
system,may |
R6609 |
T10056 |
T10058 |
arg1Of |
system,be |
R6610 |
T10056 |
T10059 |
arg2Of |
system,dysregulated |
R6611 |
T10059 |
T10052 |
arg2Of |
dysregulated,suggests |
R6612 |
T10059 |
T10053 |
arg1Of |
dysregulated,that |
R6613 |
T10059 |
T10057 |
arg2Of |
dysregulated,may |
R6614 |
T10059 |
T10058 |
arg2Of |
dysregulated,be |
R6615 |
T10059 |
T10062 |
arg1Of |
dysregulated,in |
R6616 |
T10061 |
T10059 |
arg1Of |
IL-1Ra,dysregulated |
R6617 |
T10061 |
T10060 |
arg2Of |
IL-1Ra,by |
R6618 |
T10063 |
T10062 |
arg2Of |
tumors,in |
R6619 |
T10064 |
T10065 |
arg1Of |
IL-1Ra,has |
R6620 |
T10064 |
T10066 |
arg1Of |
IL-1Ra,been |
R6621 |
T10064 |
T10067 |
arg2Of |
IL-1Ra,shown |
R6622 |
T10064 |
T10069 |
arg1Of |
IL-1Ra,inhibit |
R6623 |
T10067 |
T10065 |
arg2Of |
shown,has |
R6624 |
T10067 |
T10066 |
arg2Of |
shown,been |
R6625 |
T10069 |
T10067 |
arg3Of |
inhibit,shown |
R6626 |
T10069 |
T10068 |
arg1Of |
inhibit,to |
R6627 |
T10069 |
T10080 |
arg1Of |
inhibit,[ |
R6628 |
T10069 |
T10083 |
arg1Of |
inhibit,"," |
R6629 |
T10069 |
T10084 |
arg1Of |
inhibit,[ |
R6630 |
T10069 |
T10087 |
arg1Of |
inhibit,"," |
R6631 |
T10069 |
T10088 |
arg1Of |
inhibit,[ |
R6632 |
T10071 |
T10069 |
arg2Of |
progression,inhibit |
R6633 |
T10071 |
T10070 |
arg1Of |
progression,tumor |
R6634 |
T10071 |
T10072 |
arg1Of |
progression,in |
R6635 |
T10073 |
T10074 |
arg1Of |
prostate,"," |
R6636 |
T10074 |
T10077 |
arg1Of |
",",and |
R6637 |
T10075 |
T10074 |
arg2Of |
breast,"," |
R6638 |
T10077 |
T10072 |
arg2Of |
and,in |
R6639 |
T10077 |
T10076 |
arg1Of |
and,"," |
R6640 |
T10079 |
T10077 |
arg2Of |
cancer,and |
R6641 |
T10079 |
T10078 |
arg1Of |
cancer,skin |
R6642 |
T10081 |
T10080 |
arg2Of |
14,[ |
R6643 |
T10082 |
T10080 |
arg3Of |
],[ |
R6644 |
T10085 |
T10084 |
arg2Of |
15,[ |
R6645 |
T10086 |
T10084 |
arg3Of |
],[ |
R6646 |
T10089 |
T10088 |
arg2Of |
16,[ |
R6647 |
T10090 |
T10088 |
arg3Of |
],[ |
R6648 |
T10092 |
T10091 |
arg1Of |
IL-1Ra,Intracellular |
R6649 |
T10092 |
T10093 |
arg1Of |
IL-1Ra,( |
R6650 |
T10092 |
T10096 |
arg1Of |
IL-1Ra,inhibits |
R6651 |
T10092 |
T10105 |
arg1Of |
IL-1Ra,blocking |
R6652 |
T10094 |
T10093 |
arg2Of |
icIL-1Ra,( |
R6653 |
T10095 |
T10093 |
arg3Of |
),( |
R6654 |
T10096 |
T10104 |
arg1Of |
inhibits,by |
R6655 |
T10097 |
T10098 |
arg1Of |
IL-6,and |
R6656 |
T10099 |
T10098 |
arg2Of |
IL-8,and |
R6657 |
T10100 |
T10096 |
arg2Of |
production,inhibits |
R6658 |
T10100 |
T10097 |
arg1Of |
production,IL-6 |
R6659 |
T10100 |
T10099 |
arg1Of |
production,IL-8 |
R6660 |
T10100 |
T10101 |
arg1Of |
production,in |
R6661 |
T10103 |
T10101 |
arg2Of |
cells,in |
R6662 |
T10103 |
T10102 |
arg1Of |
cells,Caco-2 |
R6663 |
T10105 |
T10104 |
arg2Of |
blocking,by |
R6664 |
T10107 |
T10105 |
arg2Of |
pathways,blocking |
R6665 |
T10107 |
T10106 |
arg1Of |
pathways,NF-κB |
R6666 |
T10107 |
T10108 |
arg1Of |
pathways,[ |
R6667 |
T10109 |
T10108 |
arg2Of |
37,[ |
R6668 |
T10110 |
T10108 |
arg3Of |
],[ |
R6669 |
T10111 |
T10112 |
arg1Of |
We,found |
R6670 |
T10115 |
T10114 |
arg1Of |
levels,the |
R6671 |
T10115 |
T10116 |
arg1Of |
levels,of |
R6672 |
T10115 |
T10118 |
arg1Of |
levels,were |
R6673 |
T10115 |
T10120 |
arg2Of |
levels,elevated |
R6674 |
T10117 |
T10116 |
arg2Of |
IL-1Ra,of |
R6675 |
T10120 |
T10112 |
arg2Of |
elevated,found |
R6676 |
T10120 |
T10113 |
arg1Of |
elevated,that |
R6677 |
T10120 |
T10118 |
arg2Of |
elevated,were |
R6678 |
T10120 |
T10119 |
arg1Of |
elevated,significantly |
R6679 |
T10120 |
T10121 |
arg1Of |
elevated,in |
R6680 |
T10124 |
T10121 |
arg2Of |
tissues,in |
R6681 |
T10124 |
T10122 |
arg1Of |
tissues,the |
R6682 |
T10124 |
T10123 |
arg1Of |
tissues,tumor |
R6683 |
T10124 |
T10125 |
arg1Of |
tissues,of |
R6684 |
T10127 |
T10125 |
arg2Of |
mice,of |
R6685 |
T10127 |
T10126 |
arg1Of |
mice,CCR5−/− |
R6686 |
T10127 |
T10128 |
arg2Of |
mice,inoculated |
R6687 |
T10128 |
T10129 |
arg1Of |
inoculated,with |
R6688 |
T10132 |
T10129 |
arg2Of |
cells,with |
R6689 |
T10132 |
T10130 |
arg1Of |
cells,B16 |
R6690 |
T10132 |
T10131 |
arg1Of |
cells,melanoma |
R6691 |
T10133 |
T10134 |
arg1Of |
Taken,together |
R6692 |
T10137 |
T10136 |
arg1Of |
data,these |
R6693 |
T10137 |
T10138 |
arg1Of |
data,indicate |
R6694 |
T10138 |
T10133 |
modOf |
indicate,Taken |
R6695 |
T10138 |
T10135 |
arg1Of |
indicate,"," |
R6696 |
T10139 |
T10140 |
arg1Of |
IL-1Ra,could |
R6697 |
T10139 |
T10141 |
arg1Of |
IL-1Ra,be |
R6698 |
T10139 |
T10143 |
arg2Of |
IL-1Ra,involved |
R6699 |
T10143 |
T10138 |
arg2Of |
involved,indicate |
R67 |
T292 |
T284 |
arg1Of |
expression,C-C |
R6700 |
T10143 |
T10140 |
arg2Of |
involved,could |
R6701 |
T10143 |
T10141 |
arg2Of |
involved,be |
R6702 |
T10143 |
T10142 |
arg1Of |
involved,critically |
R6703 |
T10143 |
T10144 |
arg1Of |
involved,in |
R6704 |
T10143 |
T10152 |
arg1Of |
involved,through |
R6705 |
T10148 |
T10144 |
arg2Of |
inhibition,in |
R6706 |
T10148 |
T10145 |
arg1Of |
inhibition,the |
R6707 |
T10148 |
T10146 |
arg1Of |
inhibition,tumor |
R6708 |
T10148 |
T10147 |
arg1Of |
inhibition,growth |
R6709 |
T10148 |
T10149 |
arg1Of |
inhibition,of |
R6710 |
T10151 |
T10149 |
arg2Of |
mice,of |
R6711 |
T10151 |
T10150 |
arg1Of |
mice,CCR5−/− |
R6712 |
T10154 |
T10152 |
arg2Of |
inactivation,through |
R6713 |
T10154 |
T10153 |
arg1Of |
inactivation,the |
R6714 |
T10154 |
T10155 |
arg1Of |
inactivation,of |
R6715 |
T10154 |
T10157 |
arg1Of |
inactivation,in |
R6716 |
T10156 |
T10155 |
arg2Of |
NF-κB,of |
R6717 |
T10160 |
T10157 |
arg2Of |
study,in |
R6718 |
T10160 |
T10158 |
arg1Of |
study,the |
R6719 |
T10160 |
T10159 |
arg1Of |
study,present |
R6720 |
T10161 |
T10162 |
arg1Of |
CCR5,increases |
R6721 |
T10161 |
T10170 |
arg1Of |
CCR5,inhibits |
R6722 |
T10162 |
T10165 |
arg1Of |
increases,in |
R6723 |
T10162 |
T10169 |
arg1Of |
increases,and |
R6724 |
T10164 |
T10162 |
arg2Of |
growth,increases |
R6725 |
T10164 |
T10163 |
arg1Of |
growth,tumor |
R6726 |
T10168 |
T10165 |
arg2Of |
model,in |
R6727 |
T10168 |
T10166 |
arg1Of |
model,a |
R6728 |
T10168 |
T10167 |
arg1Of |
model,local |
R6729 |
T10170 |
T10169 |
arg2Of |
inhibits,and |
R6730 |
T10172 |
T10170 |
arg2Of |
efficacy,inhibits |
R6731 |
T10172 |
T10171 |
arg1Of |
efficacy,the |
R6732 |
T10172 |
T10173 |
arg1Of |
efficacy,of |
R6733 |
T10172 |
T10178 |
arg1Of |
efficacy,in |
R6734 |
T10177 |
T10173 |
arg2Of |
vaccine,of |
R6735 |
T10177 |
T10174 |
arg1Of |
vaccine,a |
R6736 |
T10177 |
T10175 |
arg1Of |
vaccine,dendrite |
R6737 |
T10177 |
T10176 |
arg1Of |
vaccine,cell |
R6738 |
T10180 |
T10178 |
arg2Of |
mice,in |
R6739 |
T10180 |
T10179 |
arg1Of |
mice,CCR5+/+ |
R6740 |
T10180 |
T10181 |
arg1Of |
mice,compared |
R6741 |
T10182 |
T10181 |
arg2Of |
with,compared |
R6742 |
T10184 |
T10182 |
arg2Of |
mice,with |
R6743 |
T10184 |
T10183 |
arg1Of |
mice,CCR5−/− |
R6744 |
T10184 |
T10185 |
arg1Of |
mice,[ |
R6745 |
T10186 |
T10185 |
arg2Of |
10,[ |
R6746 |
T10187 |
T10185 |
arg3Of |
],[ |
R6747 |
T10189 |
T10188 |
arg1Of |
J,Cheng |
R6748 |
T10189 |
T10190 |
arg1Of |
J,and |
R6749 |
T10190 |
T10193 |
arg1Of |
and,examined |
R6750 |
T10192 |
T10190 |
arg2Of |
RS,and |
R6751 |
T10192 |
T10191 |
arg1Of |
RS,Sung |
R6752 |
T10193 |
T10208 |
arg1Of |
examined,in |
R6753 |
T10195 |
T10193 |
arg2Of |
effect,examined |
R6754 |
T10195 |
T10194 |
arg1Of |
effect,the |
R6755 |
T10195 |
T10196 |
arg1Of |
effect,of |
R6756 |
T10195 |
T10198 |
arg1Of |
effect,on |
R6757 |
T10197 |
T10196 |
arg2Of |
CCR5,of |
R6758 |
T10201 |
T10198 |
arg2Of |
response,on |
R6759 |
T10201 |
T10199 |
arg1Of |
response,the |
R6760 |
T10201 |
T10200 |
arg1Of |
response,immune |
R6761 |
T10201 |
T10202 |
arg1Of |
response,to |
R6762 |
T10204 |
T10203 |
arg1Of |
vectors,adenovirus |
R6763 |
T10204 |
T10205 |
arg1Of |
vectors,and |
R6764 |
T10205 |
T10202 |
arg2Of |
and,to |
R6765 |
T10207 |
T10205 |
arg2Of |
function,and |
R6766 |
T10207 |
T10206 |
arg1Of |
function,graft |
R6767 |
T10212 |
T10208 |
arg2Of |
model,in |
R6768 |
T10212 |
T10209 |
arg1Of |
model,an |
R6769 |
T10212 |
T10210 |
arg1Of |
model,islet |
R6770 |
T10212 |
T10211 |
arg1Of |
model,transplant |
R6771 |
T10213 |
T10214 |
arg1Of |
They,found |
R6772 |
T10217 |
T10216 |
arg1Of |
absence,CCR5 |
R6773 |
T10217 |
T10218 |
arg1Of |
absence,does |
R6774 |
T10217 |
T10220 |
arg1Of |
absence,prevent |
R6775 |
T10220 |
T10214 |
arg2Of |
prevent,found |
R6776 |
T10220 |
T10215 |
arg1Of |
prevent,that |
R6777 |
T10220 |
T10218 |
arg2Of |
prevent,does |
R6778 |
T10220 |
T10219 |
arg1Of |
prevent,not |
R6779 |
T10220 |
T10228 |
arg1Of |
prevent,[ |
R6780 |
T10224 |
T10220 |
arg2Of |
response,prevent |
R6781 |
T10224 |
T10221 |
arg1Of |
response,the |
R6782 |
T10224 |
T10222 |
arg1Of |
response,local |
R6783 |
T10224 |
T10223 |
arg1Of |
response,immune |
R6784 |
T10224 |
T10225 |
arg1Of |
response,to |
R6785 |
T10227 |
T10225 |
arg2Of |
transduction,to |
R6786 |
T10227 |
T10226 |
arg1Of |
transduction,adenovirus |
R6787 |
T10229 |
T10228 |
arg2Of |
48,[ |
R6788 |
T10230 |
T10228 |
arg3Of |
],[ |
R6789 |
T10234 |
T10233 |
arg1Of |
MC,Tan |
R6790 |
T10234 |
T10235 |
arg1Of |
MC,et |
R6791 |
T10234 |
T10236 |
arg1Of |
MC,al. |
R6792 |
T10234 |
T10237 |
arg1Of |
MC,suggested |
R6793 |
T10237 |
T10231 |
arg1Of |
suggested,Additionally |
R6794 |
T10237 |
T10232 |
arg1Of |
suggested,"," |
R6795 |
T10239 |
T10240 |
arg1Of |
disruption,of |
R6796 |
T10239 |
T10243 |
arg1Of |
disruption,"," |
R6797 |
T10239 |
T10245 |
arg1Of |
disruption,by |
R6798 |
T10239 |
T10253 |
arg1Of |
disruption,by |
R6799 |
T10239 |
T10264 |
arg1Of |
disruption,reduced |
R68 |
T292 |
T285 |
arg1Of |
expression,chemokine |
R6800 |
T10242 |
T10240 |
arg2Of |
signaling,of |
R6801 |
T10242 |
T10241 |
arg1Of |
signaling,CCR5/CCL5 |
R6802 |
T10245 |
T10244 |
arg1Of |
by,either |
R6803 |
T10245 |
T10252 |
arg1Of |
by,or |
R6804 |
T10246 |
T10245 |
arg2Of |
reducing,by |
R6805 |
T10248 |
T10246 |
arg2Of |
production,reducing |
R6806 |
T10248 |
T10247 |
arg1Of |
production,CCL5 |
R6807 |
T10248 |
T10249 |
arg1Of |
production,by |
R6808 |
T10251 |
T10249 |
arg2Of |
cells,by |
R6809 |
T10251 |
T10250 |
arg1Of |
cells,tumor |
R6810 |
T10253 |
T10252 |
arg2Of |
by,or |
R6811 |
T10255 |
T10253 |
arg2Of |
administration,by |
R6812 |
T10255 |
T10254 |
arg1Of |
administration,systemic |
R6813 |
T10255 |
T10256 |
arg1Of |
administration,of |
R6814 |
T10259 |
T10256 |
arg2Of |
inhibitor,of |
R6815 |
T10259 |
T10257 |
arg1Of |
inhibitor,a |
R6816 |
T10259 |
T10258 |
arg1Of |
inhibitor,CCR5 |
R6817 |
T10259 |
T10260 |
arg1Of |
inhibitor,( |
R6818 |
T10261 |
T10260 |
arg2Of |
TAK-779,( |
R6819 |
T10262 |
T10260 |
arg3Of |
),( |
R6820 |
T10264 |
T10237 |
arg2Of |
reduced,suggested |
R6821 |
T10264 |
T10238 |
arg1Of |
reduced,that |
R6822 |
T10264 |
T10263 |
arg1Of |
reduced,"," |
R6823 |
T10264 |
T10274 |
arg1Of |
reduced,so |
R6824 |
T10269 |
T10266 |
arg2Of |
cells,( |
R6825 |
T10269 |
T10267 |
arg1Of |
cells,regulatory |
R6826 |
T10269 |
T10268 |
arg1Of |
cells,T |
R6827 |
T10270 |
T10266 |
arg3Of |
),( |
R6828 |
T10271 |
T10264 |
arg2Of |
migration,reduced |
R6829 |
T10271 |
T10265 |
arg1Of |
migration,Treg |
R6830 |
T10271 |
T10266 |
arg1Of |
migration,( |
R6831 |
T10271 |
T10272 |
arg1Of |
migration,to |
R6832 |
T10273 |
T10272 |
arg2Of |
tumors,to |
R6833 |
T10274 |
T10275 |
arg1Of |
so,that |
R6834 |
T10276 |
T10277 |
arg1Of |
tumors,are |
R6835 |
T10276 |
T10278 |
arg1Of |
tumors,smaller |
R6836 |
T10277 |
T10274 |
arg2Of |
are,so |
R6837 |
T10278 |
T10277 |
arg2Of |
smaller,are |
R6838 |
T10278 |
T10279 |
arg1Of |
smaller,in |
R6839 |
T10281 |
T10279 |
arg2Of |
mice,in |
R6840 |
T10281 |
T10280 |
arg1Of |
mice,control |
R6841 |
T10281 |
T10282 |
arg1Of |
mice,[ |
R6842 |
T10283 |
T10282 |
arg2Of |
9,[ |
R6843 |
T10284 |
T10282 |
arg3Of |
],[ |
R6844 |
T10286 |
T10285 |
arg1Of |
data,These |
R6845 |
T10286 |
T10287 |
arg1Of |
data,support |
R6846 |
T10290 |
T10287 |
arg2Of |
premise,support |
R6847 |
T10290 |
T10288 |
arg1Of |
premise,the |
R6848 |
T10290 |
T10289 |
arg1Of |
premise,important |
R6849 |
T10292 |
T10293 |
arg1Of |
inhibition,of |
R6850 |
T10292 |
T10299 |
arg1Of |
inhibition,could |
R6851 |
T10292 |
T10300 |
arg1Of |
inhibition,be |
R6852 |
T10292 |
T10301 |
arg2Of |
inhibition,related |
R6853 |
T10295 |
T10293 |
arg2Of |
growth,of |
R6854 |
T10295 |
T10294 |
arg1Of |
growth,tumor |
R6855 |
T10295 |
T10296 |
arg1Of |
growth,in |
R6856 |
T10298 |
T10296 |
arg2Of |
mice,in |
R6857 |
T10298 |
T10297 |
arg1Of |
mice,CCR5−/− |
R6858 |
T10301 |
T10290 |
arg2Of |
related,premise |
R6859 |
T10301 |
T10291 |
arg1Of |
related,that |
R6860 |
T10301 |
T10299 |
arg2Of |
related,could |
R6861 |
T10301 |
T10300 |
arg2Of |
related,be |
R6862 |
T10301 |
T10302 |
arg1Of |
related,with |
R6863 |
T10304 |
T10302 |
arg2Of |
inhibition,with |
R6864 |
T10304 |
T10303 |
arg1Of |
inhibition,the |
R6865 |
T10304 |
T10305 |
arg1Of |
inhibition,of |
R6866 |
T10307 |
T10305 |
arg2Of |
escape,of |
R6867 |
T10307 |
T10306 |
arg1Of |
escape,immune |
R6868 |
T10308 |
T10309 |
arg1Of |
Similar,to |
R6869 |
T10311 |
T10309 |
arg2Of |
finding,to |
R6870 |
T10311 |
T10310 |
arg1Of |
finding,this |
R6871 |
T10313 |
T10314 |
arg1Of |
we,found |
R6872 |
T10314 |
T10308 |
arg1Of |
found,Similar |
R6873 |
T10314 |
T10312 |
arg1Of |
found,"," |
R6874 |
T10318 |
T10316 |
arg1Of |
mice,the |
R6875 |
T10318 |
T10317 |
arg1Of |
mice,CCR5+/+ |
R6876 |
T10318 |
T10319 |
arg2Of |
mice,injected |
R6877 |
T10318 |
T10324 |
arg1Of |
mice,have |
R6878 |
T10319 |
T10320 |
arg1Of |
injected,with |
R6879 |
T10322 |
T10320 |
arg2Of |
cells,with |
R6880 |
T10322 |
T10321 |
arg1Of |
cells,melanoma |
R6881 |
T10324 |
T10314 |
arg2Of |
have,found |
R6882 |
T10324 |
T10315 |
arg1Of |
have,that |
R6883 |
T10324 |
T10323 |
arg1Of |
have,apparently |
R6884 |
T10327 |
T10324 |
arg2Of |
number,have |
R6885 |
T10327 |
T10325 |
arg1Of |
number,a |
R6886 |
T10327 |
T10326 |
arg1Of |
number,lower |
R6887 |
T10327 |
T10328 |
arg1Of |
number,of |
R6888 |
T10331 |
T10329 |
arg1Of |
cells,cytotoxic |
R6889 |
T10331 |
T10330 |
arg1Of |
cells,T |
R6890 |
T10331 |
T10332 |
arg1Of |
cells,( |
R6891 |
T10331 |
T10338 |
arg1Of |
cells,and |
R6892 |
T10336 |
T10332 |
arg2Of |
cells,( |
R6893 |
T10336 |
T10333 |
arg1Of |
cells,CD8+positive |
R6894 |
T10336 |
T10334 |
arg1Of |
cells,T |
R6895 |
T10336 |
T10335 |
arg1Of |
cells,Lymphocytes |
R6896 |
T10337 |
T10332 |
arg3Of |
),( |
R6897 |
T10338 |
T10328 |
arg2Of |
and,of |
R6898 |
T10338 |
T10354 |
arg1Of |
and,"," |
R6899 |
T10338 |
T10355 |
arg1Of |
and,in |
R69 |
T292 |
T286 |
arg1Of |
expression,receptor |
R6900 |
T10341 |
T10339 |
arg1Of |
cells,natural |
R6901 |
T10341 |
T10340 |
arg1Of |
cells,killer |
R6902 |
T10341 |
T10342 |
arg1Of |
cells,( |
R6903 |
T10341 |
T10351 |
arg1Of |
cells,as |
R6904 |
T10346 |
T10342 |
arg2Of |
cells,( |
R6905 |
T10346 |
T10343 |
arg1Of |
cells,CD57 |
R6906 |
T10346 |
T10344 |
arg1Of |
cells,positive |
R6907 |
T10346 |
T10345 |
arg1Of |
cells,NK |
R6908 |
T10347 |
T10342 |
arg3Of |
),( |
R6909 |
T10351 |
T10338 |
arg2Of |
as,and |
R6910 |
T10351 |
T10348 |
arg1Of |
as,"," |
R6911 |
T10351 |
T10349 |
arg1Of |
as,as |
R6912 |
T10351 |
T10350 |
arg1Of |
as,well |
R6913 |
T10353 |
T10351 |
arg2Of |
cells,as |
R6914 |
T10353 |
T10352 |
arg1Of |
cells,dendrite |
R6915 |
T10357 |
T10355 |
arg2Of |
tissues,in |
R6916 |
T10357 |
T10356 |
arg1Of |
tissues,spleen |
R6917 |
T10357 |
T10358 |
arg2Of |
tissues,compared |
R6918 |
T10358 |
T10359 |
arg1Of |
compared,to |
R6919 |
T10360 |
T10359 |
arg2Of |
those,to |
R6920 |
T10360 |
T10361 |
arg1Of |
those,without |
R6921 |
T10363 |
T10361 |
arg2Of |
cells,without |
R6922 |
T10363 |
T10362 |
arg1Of |
cells,melanoma |
R6923 |
T10366 |
T10365 |
arg1Of |
lymphocytes,the |
R6924 |
T10366 |
T10367 |
arg1Of |
lymphocytes,of |
R6925 |
T10366 |
T10371 |
arg1Of |
lymphocytes,did |
R6926 |
T10366 |
T10373 |
arg1Of |
lymphocytes,decrease |
R6927 |
T10370 |
T10367 |
arg2Of |
mice,of |
R6928 |
T10370 |
T10368 |
arg1Of |
mice,the |
R6929 |
T10370 |
T10369 |
arg1Of |
mice,CCR5−/− |
R6930 |
T10373 |
T10364 |
arg1Of |
decrease,But |
R6931 |
T10373 |
T10371 |
arg2Of |
decrease,did |
R6932 |
T10373 |
T10372 |
arg1Of |
decrease,not |
R6933 |
T10373 |
T10374 |
arg1Of |
decrease,when |
R6934 |
T10375 |
T10374 |
arg2Of |
injected,when |
R6935 |
T10375 |
T10376 |
arg1Of |
injected,with |
R6936 |
T10378 |
T10376 |
arg2Of |
cells,with |
R6937 |
T10378 |
T10377 |
arg1Of |
cells,melanoma |
R6938 |
T10380 |
T10379 |
arg1Of |
differences,These |
R6939 |
T10380 |
T10381 |
arg1Of |
differences,of |
R6940 |
T10380 |
T10393 |
arg1Of |
differences,"," |
R6941 |
T10380 |
T10394 |
arg1Of |
differences,involving |
R6942 |
T10380 |
T10399 |
arg1Of |
differences,may |
R6943 |
T10380 |
T10400 |
arg1Of |
differences,be |
R6944 |
T10380 |
T10401 |
arg2Of |
differences,connected |
R6945 |
T10384 |
T10381 |
arg2Of |
response,of |
R6946 |
T10384 |
T10382 |
arg1Of |
response,the |
R6947 |
T10384 |
T10383 |
arg1Of |
response,immune |
R6948 |
T10384 |
T10385 |
arg1Of |
response,between |
R6949 |
T10388 |
T10386 |
arg1Of |
mice,the |
R6950 |
T10388 |
T10387 |
arg1Of |
mice,CCR5+/+ |
R6951 |
T10388 |
T10389 |
arg1Of |
mice,and |
R6952 |
T10389 |
T10385 |
arg2Of |
and,between |
R6953 |
T10392 |
T10389 |
arg2Of |
mice,and |
R6954 |
T10392 |
T10390 |
arg1Of |
mice,the |
R6955 |
T10392 |
T10391 |
arg1Of |
mice,CCR5−/− |
R6956 |
T10397 |
T10394 |
arg2Of |
tolerance,involving |
R6957 |
T10397 |
T10395 |
arg1Of |
tolerance,tumor |
R6958 |
T10397 |
T10396 |
arg1Of |
tolerance,immune |
R6959 |
T10401 |
T10398 |
arg1Of |
connected,"," |
R6960 |
T10401 |
T10399 |
arg2Of |
connected,may |
R6961 |
T10401 |
T10400 |
arg2Of |
connected,be |
R6962 |
T10401 |
T10402 |
arg1Of |
connected,with |
R6963 |
T10404 |
T10402 |
arg2Of |
inhibition,with |
R6964 |
T10404 |
T10403 |
arg1Of |
inhibition,the |
R6965 |
T10404 |
T10405 |
arg1Of |
inhibition,of |
R6966 |
T10407 |
T10405 |
arg2Of |
progression,of |
R6967 |
T10407 |
T10406 |
arg1Of |
progression,cancer |
R6968 |
T10408 |
T10409 |
arg1Of |
Taken,together |
R6969 |
T10415 |
T10411 |
arg2Of |
experiment,in |
R6970 |
T10415 |
T10412 |
arg1Of |
experiment,the |
R6971 |
T10415 |
T10413 |
arg1Of |
experiment,cytokine |
R6972 |
T10415 |
T10414 |
arg1Of |
experiment,array |
R6973 |
T10418 |
T10417 |
arg1Of |
level,the |
R6974 |
T10418 |
T10419 |
arg1Of |
level,of |
R6975 |
T10418 |
T10435 |
arg1Of |
level,was |
R6976 |
T10418 |
T10436 |
arg2Of |
level,increased |
R6977 |
T10420 |
T10419 |
arg2Of |
MIP-1α,of |
R6978 |
T10420 |
T10421 |
arg1Of |
MIP-1α,( |
R6979 |
T10422 |
T10421 |
arg2Of |
which,( |
R6980 |
T10422 |
T10423 |
arg1Of |
which,has |
R6981 |
T10426 |
T10423 |
arg2Of |
activity,has |
R6982 |
T10426 |
T10424 |
arg1Of |
activity,a |
R6983 |
T10426 |
T10425 |
arg1Of |
activity,potent |
R6984 |
T10426 |
T10427 |
arg1Of |
activity,of |
R6985 |
T10429 |
T10430 |
arg1Of |
cell,and |
R6986 |
T10431 |
T10430 |
arg2Of |
B,and |
R6987 |
T10433 |
T10427 |
arg2Of |
migration,of |
R6988 |
T10433 |
T10428 |
arg1Of |
migration,T |
R6989 |
T10433 |
T10429 |
arg1Of |
migration,cell |
R6990 |
T10433 |
T10431 |
arg1Of |
migration,B |
R6991 |
T10433 |
T10432 |
arg1Of |
migration,cell |
R6992 |
T10434 |
T10421 |
arg3Of |
),( |
R6993 |
T10436 |
T10408 |
modOf |
increased,Taken |
R6994 |
T10436 |
T10410 |
arg1Of |
increased,"," |
R6995 |
T10436 |
T10411 |
arg1Of |
increased,in |
R6996 |
T10436 |
T10416 |
arg1Of |
increased,"," |
R6997 |
T10436 |
T10435 |
arg2Of |
increased,was |
R6998 |
T10436 |
T10437 |
arg1Of |
increased,in |
R6999 |
T10440 |
T10437 |
arg2Of |
mice,in |
R70 |
T292 |
T287 |
arg1Of |
expression,type |
R7000 |
T10440 |
T10438 |
arg1Of |
mice,the |
R7001 |
T10440 |
T10439 |
arg1Of |
mice,CCR5−/− |
R7002 |
T10440 |
T10441 |
arg2Of |
mice,compared |
R7003 |
T10441 |
T10442 |
arg1Of |
compared,with |
R7004 |
T10443 |
T10442 |
arg2Of |
those,with |
R7005 |
T10443 |
T10444 |
arg1Of |
those,in |
R7006 |
T10447 |
T10444 |
arg2Of |
mice,in |
R7007 |
T10447 |
T10445 |
arg1Of |
mice,the |
R7008 |
T10447 |
T10446 |
arg1Of |
mice,CCR5+/+ |
R7009 |
T10451 |
T10450 |
arg1Of |
increased,relatively |
R7010 |
T10455 |
T10451 |
arg1Of |
lymphocytes,increased |
R7011 |
T10455 |
T10452 |
arg1Of |
lymphocytes,tumor |
R7012 |
T10455 |
T10453 |
arg2Of |
lymphocytes,associated |
R7013 |
T10455 |
T10454 |
arg1Of |
lymphocytes,cytotoxic |
R7014 |
T10455 |
T10456 |
arg1Of |
lymphocytes,could |
R7015 |
T10455 |
T10457 |
arg1Of |
lymphocytes,play |
R7016 |
T10457 |
T10448 |
arg1Of |
play,Thus |
R7017 |
T10457 |
T10449 |
arg1Of |
play,"," |
R7018 |
T10457 |
T10456 |
arg2Of |
play,could |
R7019 |
T10457 |
T10461 |
arg1Of |
play,in |
R7020 |
T10460 |
T10457 |
arg2Of |
role,play |
R7021 |
T10460 |
T10458 |
arg1Of |
role,an |
R7022 |
T10460 |
T10459 |
arg1Of |
role,important |
R7023 |
T10462 |
T10461 |
arg2Of |
inhibiting,in |
R7024 |
T10465 |
T10462 |
arg2Of |
growth,inhibiting |
R7025 |
T10465 |
T10463 |
arg1Of |
growth,the |
R7026 |
T10465 |
T10464 |
arg1Of |
growth,tumor |
R7027 |
T10465 |
T10466 |
arg1Of |
growth,in |
R7028 |
T10468 |
T10466 |
arg2Of |
mice,in |
R7029 |
T10468 |
T10467 |
arg1Of |
mice,CCR5−/− |
R7030 |
T10469 |
T10470 |
arg1Of |
Activation,of |
R7031 |
T10469 |
T10472 |
arg1Of |
Activation,could |
R7032 |
T10469 |
T10473 |
arg1Of |
Activation,modulate |
R7033 |
T10471 |
T10470 |
arg2Of |
NF-κB,of |
R7034 |
T10473 |
T10472 |
arg2Of |
modulate,could |
R7035 |
T10475 |
T10474 |
arg1Of |
localization,subcellular |
R7036 |
T10475 |
T10476 |
arg1Of |
localization,of |
R7037 |
T10475 |
T10479 |
arg1Of |
localization,and |
R7038 |
T10478 |
T10476 |
arg2Of |
cells,of |
R7039 |
T10478 |
T10477 |
arg1Of |
cells,NK |
R7040 |
T10479 |
T10473 |
arg2Of |
and,modulate |
R7041 |
T10480 |
T10479 |
arg2Of |
pathogenesis,and |
R7042 |
T10480 |
T10481 |
arg1Of |
pathogenesis,[ |
R7043 |
T10482 |
T10481 |
arg2Of |
49,[ |
R7044 |
T10483 |
T10481 |
arg3Of |
],[ |
R7045 |
T10484 |
T10485 |
arg1Of |
Inhibition,of |
R7046 |
T10484 |
T10488 |
arg1Of |
Inhibition,prevented |
R7047 |
T10484 |
T10495 |
arg1Of |
Inhibition,increased |
R7048 |
T10484 |
T10499 |
arg1Of |
Inhibition,decreasing |
R7049 |
T10487 |
T10485 |
arg2Of |
activity,of |
R7050 |
T10487 |
T10486 |
arg1Of |
activity,NF-κB |
R7051 |
T10488 |
T10493 |
arg1Of |
prevented,and |
R7052 |
T10491 |
T10488 |
arg2Of |
depletion,prevented |
R7053 |
T10491 |
T10489 |
arg1Of |
depletion,NK |
R7054 |
T10491 |
T10490 |
arg1Of |
depletion,cell |
R7055 |
T10493 |
T10492 |
arg1Of |
and,"," |
R7056 |
T10495 |
T10493 |
arg2Of |
increased,and |
R7057 |
T10495 |
T10494 |
arg1Of |
increased,thus |
R7058 |
T10495 |
T10498 |
arg1Of |
increased,by |
R7059 |
T10497 |
T10495 |
arg2Of |
activity,increased |
R7060 |
T10497 |
T10496 |
arg1Of |
activity,anti-tumor |
R7061 |
T10499 |
T10498 |
arg2Of |
decreasing,by |
R7062 |
T10499 |
T10502 |
arg1Of |
decreasing,[ |
R7063 |
T10501 |
T10499 |
arg2Of |
production,decreasing |
R7064 |
T10501 |
T10500 |
arg1Of |
production,IL-6 |
R7065 |
T10503 |
T10502 |
arg2Of |
50,[ |
R7066 |
T10504 |
T10502 |
arg3Of |
],[ |
R7067 |
T10509 |
T10508 |
arg2Of |
NF-κB,decreased |
R7068 |
T10509 |
T10510 |
arg1Of |
NF-κB,and |
R7069 |
T10510 |
T10507 |
arg1Of |
and,the |
R7070 |
T10510 |
T10513 |
arg1Of |
and,could |
R7071 |
T10510 |
T10515 |
arg1Of |
and,be |
R7072 |
T10510 |
T10516 |
arg2Of |
and,associated |
R7073 |
T10512 |
T10510 |
arg2Of |
IL-1Ra,and |
R7074 |
T10512 |
T10511 |
arg1Of |
IL-1Ra,elevated |
R7075 |
T10516 |
T10505 |
arg1Of |
associated,Thus |
R7076 |
T10516 |
T10506 |
arg1Of |
associated,"," |
R7077 |
T10516 |
T10513 |
arg2Of |
associated,could |
R7078 |
T10516 |
T10514 |
arg1Of |
associated,also |
R7079 |
T10516 |
T10515 |
arg2Of |
associated,be |
R7080 |
T10516 |
T10517 |
arg1Of |
associated,in |
R7081 |
T10516 |
T10523 |
arg1Of |
associated,into |
R7082 |
T10516 |
T10525 |
arg1Of |
associated,"," |
R7083 |
T10516 |
T10526 |
modOf |
associated,resulting |
R7084 |
T10519 |
T10517 |
arg2Of |
infiltration,in |
R7085 |
T10519 |
T10518 |
arg1Of |
infiltration,the |
R7086 |
T10519 |
T10520 |
arg1Of |
infiltration,of |
R7087 |
T10522 |
T10520 |
arg2Of |
lymphocytes,of |
R7088 |
T10522 |
T10521 |
arg1Of |
lymphocytes,cytotoxic |
R7089 |
T10524 |
T10523 |
arg2Of |
tumor,into |
R7090 |
T10526 |
T10527 |
arg1Of |
resulting,in |
R7091 |
T10530 |
T10527 |
arg2Of |
inhibition,in |
R7092 |
T10530 |
T10528 |
arg1Of |
inhibition,tumor |
R7093 |
T10530 |
T10529 |
arg1Of |
inhibition,growth |
R7094 |
T10532 |
T10531 |
arg2Of |
contrast,In |
R7095 |
T10534 |
T10535 |
arg1Of |
IL-23,"," |
R7096 |
T10534 |
T10542 |
arg1Of |
IL-23,increased |
R7097 |
T10540 |
T10535 |
arg2Of |
cytokine,"," |
R7098 |
T10540 |
T10536 |
arg1Of |
cytokine,a |
R7099 |
T10540 |
T10537 |
arg1Of |
cytokine,tumor |
R71 |
T292 |
T288 |
arg1Of |
expression,5 |
R7100 |
T10540 |
T10538 |
arg1Of |
cytokine,growth |
R7101 |
T10540 |
T10539 |
arg1Of |
cytokine,promoting |
R7102 |
T10542 |
T10531 |
arg1Of |
increased,In |
R7103 |
T10542 |
T10533 |
arg1Of |
increased,"," |
R7104 |
T10542 |
T10541 |
arg1Of |
increased,"," |
R7105 |
T10542 |
T10551 |
arg1Of |
increased,[ |
R7106 |
T10543 |
T10544 |
arg1Of |
NF-κB,and |
R7107 |
T10544 |
T10542 |
arg2Of |
and,increased |
R7108 |
T10544 |
T10548 |
arg1Of |
and,in |
R7109 |
T10547 |
T10544 |
arg2Of |
infiltration,and |
R7110 |
T10547 |
T10545 |
arg1Of |
infiltration,immune |
R7111 |
T10547 |
T10546 |
arg1Of |
infiltration,cell |
R7112 |
T10550 |
T10548 |
arg2Of |
tumor,in |
R7113 |
T10550 |
T10549 |
arg1Of |
tumor,oral |
R7114 |
T10552 |
T10551 |
arg2Of |
51,[ |
R7115 |
T10553 |
T10551 |
arg3Of |
],[ |
R7116 |
T10555 |
T10554 |
arg1Of |
data,These |
R7117 |
T10555 |
T10556 |
arg1Of |
data,indicate |
R7118 |
T10558 |
T10559 |
arg1Of |
NF-κB,could |
R7119 |
T10558 |
T10560 |
arg1Of |
NF-κB,be |
R7120 |
T10558 |
T10561 |
arg2Of |
NF-κB,involved |
R7121 |
T10561 |
T10556 |
arg2Of |
involved,indicate |
R7122 |
T10561 |
T10557 |
arg1Of |
involved,that |
R7123 |
T10561 |
T10559 |
arg2Of |
involved,could |
R7124 |
T10561 |
T10560 |
arg2Of |
involved,be |
R7125 |
T10561 |
T10562 |
arg1Of |
involved,in |
R7126 |
T10564 |
T10562 |
arg2Of |
cytokine,in |
R7127 |
T10564 |
T10563 |
arg1Of |
cytokine,the |
R7128 |
T10567 |
T10562 |
arg3Of |
activities,in |
R7129 |
T10567 |
T10565 |
arg2Of |
activities,mediated |
R7130 |
T10567 |
T10566 |
arg1Of |
activities,anti-tumor |
R7131 |
T10567 |
T10568 |
arg1Of |
activities,of |
R7132 |
T10570 |
T10568 |
arg2Of |
cells,of |
R7133 |
T10570 |
T10569 |
arg1Of |
cells,immune |
R7134 |
T10572 |
T10573 |
arg1Of |
is,also |
R7135 |
T10574 |
T10572 |
arg2Of |
noteworthy,is |
R7136 |
T10576 |
T10577 |
arg1Of |
IL-1Ra,inhibited |
R7137 |
T10576 |
T10582 |
arg1Of |
IL-1Ra,increasing |
R7138 |
T10577 |
T10571 |
arg1Of |
inhibited,It |
R7139 |
T10577 |
T10572 |
arg1Of |
inhibited,is |
R7140 |
T10577 |
T10574 |
arg1Of |
inhibited,noteworthy |
R7141 |
T10577 |
T10575 |
arg1Of |
inhibited,that |
R7142 |
T10577 |
T10581 |
arg1Of |
inhibited,by |
R7143 |
T10580 |
T10577 |
arg2Of |
growth,inhibited |
R7144 |
T10580 |
T10578 |
arg1Of |
growth,melanoma |
R7145 |
T10580 |
T10579 |
arg1Of |
growth,tumor |
R7146 |
T10582 |
T10581 |
arg2Of |
increasing,by |
R7147 |
T10582 |
T10589 |
arg1Of |
increasing,in |
R7148 |
T10584 |
T10582 |
arg2Of |
number,increasing |
R7149 |
T10584 |
T10583 |
arg1Of |
number,the |
R7150 |
T10584 |
T10585 |
arg1Of |
number,of |
R7151 |
T10588 |
T10585 |
arg2Of |
cells,of |
R7152 |
T10588 |
T10586 |
arg1Of |
cells,myeloid |
R7153 |
T10588 |
T10587 |
arg1Of |
cells,suppressor |
R7154 |
T10590 |
T10589 |
arg2Of |
tumor,in |
R7155 |
T10590 |
T10591 |
arg1Of |
tumor,[ |
R7156 |
T10592 |
T10591 |
arg2Of |
25,[ |
R7157 |
T10593 |
T10591 |
arg3Of |
],[ |
R7158 |
T10597 |
T10594 |
arg1Of |
incidence,The |
R7159 |
T10597 |
T10595 |
arg1Of |
incidence,3-methylcholatrene-induced |
R7160 |
T10597 |
T10596 |
arg1Of |
incidence,tumor |
R7161 |
T10597 |
T10598 |
arg1Of |
incidence,was |
R7162 |
T10597 |
T10599 |
arg2Of |
incidence,reduced |
R7163 |
T10597 |
T10606 |
arg1Of |
incidence,increased |
R7164 |
T10599 |
T10598 |
arg2Of |
reduced,was |
R7165 |
T10599 |
T10600 |
arg1Of |
reduced,in |
R7166 |
T10599 |
T10605 |
arg1Of |
reduced,but |
R7167 |
T10603 |
T10600 |
arg2Of |
mice,in |
R7168 |
T10603 |
T10601 |
arg1Of |
mice,IL-1α |
R7169 |
T10603 |
T10602 |
arg1Of |
mice,knockout |
R7170 |
T10605 |
T10604 |
arg1Of |
but,"," |
R7171 |
T10606 |
T10605 |
arg2Of |
increased,but |
R7172 |
T10606 |
T10607 |
arg1Of |
increased,in |
R7173 |
T10606 |
T10610 |
arg1Of |
increased,with |
R7174 |
T10609 |
T10607 |
arg2Of |
mice,in |
R7175 |
T10609 |
T10608 |
arg1Of |
mice,IL-1Ra |
R7176 |
T10612 |
T10611 |
arg1Of |
maturation,concomitant |
R7177 |
T10612 |
T10613 |
arg1Of |
maturation,of |
R7178 |
T10612 |
T10616 |
arg1Of |
maturation,and |
R7179 |
T10615 |
T10613 |
arg2Of |
cells,of |
R7180 |
T10615 |
T10614 |
arg1Of |
cells,NK |
R7181 |
T10616 |
T10610 |
arg2Of |
and,with |
R7182 |
T10618 |
T10616 |
arg2Of |
immunity,and |
R7183 |
T10618 |
T10617 |
arg1Of |
immunity,anti-tumor |
R7184 |
T10618 |
T10619 |
arg1Of |
immunity,[ |
R7185 |
T10620 |
T10619 |
arg2Of |
52,[ |
R7186 |
T10621 |
T10619 |
arg3Of |
],[ |
R7187 |
T10623 |
T10622 |
arg1Of |
data,These |
R7188 |
T10623 |
T10624 |
arg1Of |
data,indicate |
R7189 |
T10627 |
T10626 |
arg1Of |
decrease,the |
R7190 |
T10627 |
T10628 |
arg1Of |
decrease,of |
R7191 |
T10627 |
T10634 |
arg1Of |
decrease,of |
R7192 |
T10627 |
T10636 |
arg1Of |
decrease,could |
R7193 |
T10627 |
T10637 |
arg1Of |
decrease,be |
R7194 |
T10627 |
T10638 |
arg1Of |
decrease,significant |
R7195 |
T10629 |
T10631 |
arg1Of |
NF-κB,and |
R7196 |
T10631 |
T10628 |
arg2Of |
and,of |
R7197 |
T10631 |
T10630 |
arg1Of |
and,"," |
R7198 |
T10633 |
T10631 |
arg2Of |
increase,and |
R7199 |
T10633 |
T10632 |
arg1Of |
increase,thus |
R72 |
T292 |
T289 |
arg1Of |
expression,( |
R7200 |
T10635 |
T10634 |
arg2Of |
IL-1Ra,of |
R7201 |
T10637 |
T10624 |
arg2Of |
be,indicate |
R7202 |
T10637 |
T10625 |
arg1Of |
be,that |
R7203 |
T10637 |
T10636 |
arg2Of |
be,could |
R7204 |
T10638 |
T10637 |
arg2Of |
significant,be |
R7205 |
T10638 |
T10639 |
arg1Of |
significant,in |
R7206 |
T10642 |
T10639 |
arg2Of |
inhibition,in |
R7207 |
T10642 |
T10640 |
arg1Of |
inhibition,tumor |
R7208 |
T10642 |
T10641 |
arg1Of |
inhibition,growth |
R7209 |
T10642 |
T10643 |
arg1Of |
inhibition,of |
R7210 |
T10645 |
T10643 |
arg2Of |
mice,of |
R7211 |
T10645 |
T10644 |
arg1Of |
mice,CCR5−/− |
R7212 |
T10647 |
T10646 |
arg1Of |
data,Our |
R7213 |
T10647 |
T10649 |
arg1Of |
data,show |
R7214 |
T10649 |
T10648 |
arg1Of |
show,thus |
R7215 |
T10649 |
T10655 |
arg1Of |
show,"," |
R7216 |
T10649 |
T10656 |
arg1Of |
show,because |
R7217 |
T10651 |
T10650 |
arg1Of |
clinical,significant |
R7218 |
T10652 |
T10649 |
arg2Of |
implications,show |
R7219 |
T10652 |
T10651 |
arg1Of |
implications,clinical |
R7220 |
T10652 |
T10653 |
arg1Of |
implications,of |
R7221 |
T10654 |
T10653 |
arg2Of |
CCR5,of |
R7222 |
T10657 |
T10658 |
arg1Of |
CCR5,is |
R7223 |
T10658 |
T10663 |
arg1Of |
is,and |
R7224 |
T10661 |
T10660 |
arg1Of |
protein–coupled,G |
R7225 |
T10662 |
T10658 |
arg2Of |
receptor,is |
R7226 |
T10662 |
T10659 |
arg1Of |
receptor,a |
R7227 |
T10662 |
T10661 |
arg1Of |
receptor,protein–coupled |
R7228 |
T10663 |
T10656 |
arg2Of |
and,because |
R7229 |
T10664 |
T10665 |
arg1Of |
it,is |
R7230 |
T10664 |
T10666 |
arg1Of |
it,amenable |
R7231 |
T10664 |
T10668 |
arg2Of |
it,use |
R7232 |
T10665 |
T10663 |
arg2Of |
is,and |
R7233 |
T10666 |
T10665 |
arg2Of |
amenable,is |
R7234 |
T10668 |
T10666 |
arg2Of |
use,amenable |
R7235 |
T10668 |
T10667 |
arg1Of |
use,to |
R7236 |
T10668 |
T10669 |
arg1Of |
use,as |
R7237 |
T10672 |
T10669 |
arg2Of |
molecule,as |
R7238 |
T10672 |
T10670 |
arg1Of |
molecule,a |
R7239 |
T10672 |
T10671 |
arg1Of |
molecule,small |
R7240 |
T10672 |
T10673 |
arg1Of |
molecule,for |
R7241 |
T10675 |
T10673 |
arg2Of |
inhibition,for |
R7242 |
T10675 |
T10674 |
arg1Of |
inhibition,the |
R7243 |
T10675 |
T10676 |
arg1Of |
inhibition,of |
R7244 |
T10677 |
T10676 |
arg2Of |
CCR5,of |
R7245 |
T10680 |
T10678 |
arg1Of |
compounds,Several |
R7246 |
T10680 |
T10679 |
arg1Of |
compounds,such |
R7247 |
T10680 |
T10681 |
arg1Of |
compounds,have |
R7248 |
T10680 |
T10683 |
arg1Of |
compounds,been |
R7249 |
T10680 |
T10684 |
arg2Of |
compounds,shown |
R7250 |
T10680 |
T10686 |
arg1Of |
compounds,be |
R7251 |
T10680 |
T10687 |
arg1Of |
compounds,safe |
R7252 |
T10684 |
T10681 |
arg2Of |
shown,have |
R7253 |
T10684 |
T10682 |
arg1Of |
shown,already |
R7254 |
T10684 |
T10683 |
arg2Of |
shown,been |
R7255 |
T10686 |
T10684 |
arg3Of |
be,shown |
R7256 |
T10686 |
T10685 |
arg1Of |
be,to |
R7257 |
T10687 |
T10686 |
arg2Of |
safe,be |
R7258 |
T10687 |
T10688 |
arg1Of |
safe,in |
R7259 |
T10690 |
T10688 |
arg2Of |
trials,in |
R7260 |
T10690 |
T10689 |
arg1Of |
trials,clinical |
R7261 |
T10690 |
T10691 |
arg1Of |
trials,for |
R7262 |
T10692 |
T10691 |
arg2Of |
use,for |
R7263 |
T10692 |
T10693 |
arg1Of |
use,in |
R7264 |
T10695 |
T10693 |
arg2Of |
diseases,in |
R7265 |
T10695 |
T10694 |
arg1Of |
diseases,certain |
R7266 |
T10695 |
T10697 |
arg1Of |
diseases,as |
R7267 |
T10697 |
T10696 |
arg1Of |
as,such |
R7268 |
T10698 |
T10697 |
arg2Of |
HIV,as |
R7269 |
T10698 |
T10699 |
arg1Of |
HIV,[ |
R7270 |
T10700 |
T10699 |
arg2Of |
53,[ |
R7271 |
T10701 |
T10699 |
arg3Of |
],[ |
R7272 |
T10704 |
T10705 |
arg1Of |
we,believe |
R7273 |
T10705 |
T10702 |
arg1Of |
believe,Thus |
R7274 |
T10705 |
T10703 |
arg1Of |
believe,"," |
R7275 |
T10706 |
T10707 |
arg1Of |
CCR5,is |
R7276 |
T10707 |
T10705 |
arg2Of |
is,believe |
R7277 |
T10710 |
T10707 |
arg2Of |
target,is |
R7278 |
T10710 |
T10708 |
arg1Of |
target,a |
R7279 |
T10710 |
T10709 |
arg1Of |
target,cancer |
R7280 |
T10710 |
T10711 |
arg1Of |
target,that |
R7281 |
T10710 |
T10712 |
arg1Of |
target,warrants |
R7282 |
T10714 |
T10712 |
arg2Of |
investigation,warrants |
R7283 |
T10714 |
T10713 |
arg1Of |
investigation,continued |
R7284 |
T10716 |
T10715 |
arg2Of |
summary,In |
R7285 |
T10719 |
T10718 |
arg1Of |
study,this |
R7286 |
T10719 |
T10720 |
arg1Of |
study,showed |
R7287 |
T10720 |
T10715 |
arg1Of |
showed,In |
R7288 |
T10720 |
T10717 |
arg1Of |
showed,"," |
R7289 |
T10724 |
T10722 |
arg1Of |
growth,melanoma |
R7290 |
T10724 |
T10723 |
arg1Of |
growth,cells |
R7291 |
T10724 |
T10725 |
arg1Of |
growth,was |
R7292 |
T10724 |
T10726 |
arg2Of |
growth,inhibited |
R7293 |
T10726 |
T10720 |
arg2Of |
inhibited,showed |
R7294 |
T10726 |
T10721 |
arg1Of |
inhibited,that |
R7295 |
T10726 |
T10725 |
arg2Of |
inhibited,was |
R7296 |
T10726 |
T10727 |
arg1Of |
inhibited,via |
R7297 |
T10728 |
T10727 |
arg2Of |
modulation,via |
R7298 |
T10728 |
T10729 |
arg1Of |
modulation,of |
R7299 |
T10731 |
T10729 |
arg2Of |
pathways,of |
R73 |
T292 |
T293 |
arg1Of |
expression,and |
R7300 |
T10731 |
T10730 |
arg1Of |
pathways,NF-κB/IL-1Ra |
R7301 |
T10731 |
T10732 |
arg1Of |
pathways,in |
R7302 |
T10734 |
T10732 |
arg2Of |
mice,in |
R7303 |
T10734 |
T10733 |
arg1Of |
mice,CCR5−/− |
R74 |
T293 |
T283 |
arg2Of |
and,of |
R75 |
T295 |
T293 |
arg2Of |
development,and |
R76 |
T295 |
T294 |
arg1Of |
development,tumor |
R77 |
T297 |
T280 |
arg1Of |
we,evaluate |
R78 |
T297 |
T298 |
arg1Of |
we,compared |
R79 |
T298 |
T279 |
modOf |
compared,To |
R80 |
T298 |
T296 |
arg1Of |
compared,"," |
R81 |
T300 |
T298 |
arg2Of |
growth,compared |
R82 |
T300 |
T299 |
arg1Of |
growth,melanoma |
R83 |
T300 |
T301 |
arg1Of |
growth,in |
R838 |
T1768 |
T1769 |
arg1Of |
Chemokines,are |
R839 |
T1772 |
T1769 |
arg2Of |
molecules,are |
R84 |
T303 |
T302 |
arg1Of |
knockout,CCR5 |
R840 |
T1772 |
T1770 |
arg1Of |
molecules,small |
R841 |
T1772 |
T1771 |
arg1Of |
molecules,soluble |
R842 |
T1772 |
T1773 |
arg1Of |
molecules,that |
R843 |
T1772 |
T1774 |
arg1Of |
molecules,are |
R844 |
T1772 |
T1776 |
arg2Of |
molecules,known |
R845 |
T1776 |
T1774 |
arg2Of |
known,are |
R846 |
T1776 |
T1775 |
arg1Of |
known,best |
R847 |
T1776 |
T1777 |
arg1Of |
known,for |
R848 |
T1780 |
T1777 |
arg2Of |
ability,for |
R849 |
T1780 |
T1778 |
arg1Of |
ability,their |
R85 |
T303 |
T304 |
arg1Of |
knockout,( |
R850 |
T1780 |
T1779 |
arg1Of |
ability,potent |
R851 |
T1780 |
T1781 |
modOf |
ability,to |
R852 |
T1782 |
T1781 |
arg1Of |
induce,to |
R853 |
T1782 |
T1786 |
arg1Of |
induce,by |
R854 |
T1785 |
T1782 |
arg2Of |
growth,induce |
R855 |
T1785 |
T1783 |
arg1Of |
growth,cancer |
R856 |
T1785 |
T1784 |
arg1Of |
growth,cell |
R857 |
T1787 |
T1786 |
arg2Of |
inflammation,by |
R858 |
T1789 |
T1788 |
arg1Of |
types,Many |
R859 |
T1789 |
T1790 |
arg1Of |
types,of |
R86 |
T305 |
T304 |
arg2Of |
CCR5−/−,( |
R860 |
T1789 |
T1793 |
arg1Of |
types,express |
R861 |
T1792 |
T1790 |
arg2Of |
cells,of |
R862 |
T1792 |
T1791 |
arg1Of |
cells,cancer |
R863 |
T1793 |
T1798 |
arg1Of |
express,[ |
R864 |
T1794 |
T1795 |
arg1Of |
chemokines,and |
R865 |
T1795 |
T1793 |
arg2Of |
and,express |
R866 |
T1797 |
T1795 |
arg2Of |
receptors,and |
R867 |
T1797 |
T1796 |
arg1Of |
receptors,chemokine |
R868 |
T1799 |
T1798 |
arg2Of |
1,[ |
R869 |
T1800 |
T1798 |
arg3Of |
],[ |
R87 |
T306 |
T304 |
arg3Of |
),( |
R870 |
T1803 |
T1801 |
arg1Of |
evidence,The |
R871 |
T1803 |
T1802 |
arg2Of |
evidence,accumulated |
R872 |
T1803 |
T1804 |
arg1Of |
evidence,indicates |
R873 |
T1810 |
T1808 |
arg2Of |
motif,( |
R874 |
T1810 |
T1809 |
arg1Of |
motif,C-C |
R875 |
T1811 |
T1808 |
arg3Of |
),( |
R876 |
T1812 |
T1806 |
arg1Of |
ligand,the |
R877 |
T1812 |
T1807 |
arg1Of |
ligand,chemokine |
R878 |
T1812 |
T1808 |
arg1Of |
ligand,( |
R879 |
T1812 |
T1813 |
arg1Of |
ligand,5 |
R88 |
T307 |
T303 |
arg1Of |
mice,knockout |
R880 |
T1812 |
T1814 |
arg1Of |
ligand,( |
R881 |
T1812 |
T1817 |
arg1Of |
ligand,and |
R882 |
T1815 |
T1814 |
arg2Of |
CCL5,( |
R883 |
T1816 |
T1814 |
arg3Of |
),( |
R884 |
T1817 |
T1834 |
arg1Of |
and,may |
R885 |
T1817 |
T1835 |
arg1Of |
and,be |
R886 |
T1817 |
T1837 |
arg2Of |
and,involved |
R887 |
T1820 |
T1817 |
arg2Of |
receptor,and |
R888 |
T1820 |
T1818 |
arg1Of |
receptor,C-C |
R889 |
T1820 |
T1819 |
arg1Of |
receptor,chemokine |
R89 |
T307 |
T308 |
arg1Of |
mice,and |
R890 |
T1820 |
T1821 |
arg1Of |
receptor,( |
R891 |
T1820 |
T1824 |
arg1Of |
receptor,"," |
R892 |
T1820 |
T1825 |
arg1Of |
receptor,which |
R893 |
T1820 |
T1826 |
arg1Of |
receptor,are |
R894 |
T1822 |
T1821 |
arg2Of |
CCR5,( |
R895 |
T1823 |
T1821 |
arg3Of |
),( |
R896 |
T1829 |
T1826 |
arg2Of |
factors,are |
R897 |
T1829 |
T1827 |
arg1Of |
factors,potent |
R898 |
T1829 |
T1828 |
arg1Of |
factors,chemotactic |
R899 |
T1829 |
T1830 |
arg1Of |
factors,for |
R90 |
T308 |
T301 |
arg2Of |
and,in |
R900 |
T1832 |
T1830 |
arg2Of |
cells,for |
R901 |
T1832 |
T1831 |
arg1Of |
cells,inflammatory |
R902 |
T1837 |
T1804 |
arg2Of |
involved,indicates |
R903 |
T1837 |
T1805 |
arg1Of |
involved,that |
R9034 |
T13209 |
T13208 |
arg1Of |
Statement,Ethics |
R9035 |
T13211 |
T13210 |
arg1Of |
experiments,All |
R9036 |
T13211 |
T13212 |
arg1Of |
experiments,were |
R9037 |
T13211 |
T13213 |
arg2Of |
experiments,approved |
R9038 |
T13211 |
T13215 |
arg2Of |
experiments,carried |
R9039 |
T13213 |
T13214 |
arg1Of |
approved,and |
R904 |
T1837 |
T1833 |
arg1Of |
involved,"," |
R9040 |
T13214 |
T13212 |
arg2Of |
and,were |
R9041 |
T13214 |
T13217 |
arg1Of |
and,according |
R9042 |
T13214 |
T13221 |
arg1Of |
and,for |
R9043 |
T13215 |
T13214 |
arg2Of |
carried,and |
R9044 |
T13215 |
T13216 |
arg1Of |
carried,out |
R9045 |
T13218 |
T13217 |
arg2Of |
to,according |
R9046 |
T13220 |
T13218 |
arg2Of |
Guide,to |
R9047 |
T13220 |
T13219 |
arg1Of |
Guide,the |
R9048 |
T13223 |
T13224 |
arg1Of |
Care,and |
R9049 |
T13224 |
T13221 |
arg2Of |
and,for |
R905 |
T1837 |
T1834 |
arg2Of |
involved,may |
R9050 |
T13224 |
T13222 |
arg1Of |
and,the |
R9051 |
T13225 |
T13224 |
arg2Of |
Use,and |
R9052 |
T13225 |
T13226 |
arg1Of |
Use,of |
R9053 |
T13225 |
T13228 |
arg1Of |
Use,[ |
R9054 |
T13227 |
T13226 |
arg2Of |
Animals,of |
R9055 |
T13231 |
T13228 |
arg2Of |
Committee,[ |
R9056 |
T13231 |
T13229 |
arg1Of |
Committee,Animal |
R9057 |
T13231 |
T13230 |
arg1Of |
Committee,Care |
R9058 |
T13231 |
T13232 |
arg1Of |
Committee,of |
R9059 |
T13231 |
T13236 |
arg1Of |
Committee,"," |
R906 |
T1837 |
T1835 |
arg2Of |
involved,be |
R9060 |
T13235 |
T13232 |
arg2Of |
University,of |
R9061 |
T13235 |
T13233 |
arg1Of |
University,Chungbuk |
R9062 |
T13235 |
T13234 |
arg1Of |
University,National |
R9063 |
T13237 |
T13236 |
arg2Of |
Korea,"," |
R9064 |
T13237 |
T13238 |
arg1Of |
Korea,( |
R9065 |
T13239 |
T13238 |
arg2Of |
CBNUA-045-0902-01,( |
R9066 |
T13240 |
T13238 |
arg3Of |
),( |
R9067 |
T13241 |
T13228 |
arg3Of |
],[ |
R907 |
T1837 |
T1836 |
arg1Of |
involved,significantly |
R908 |
T1837 |
T1838 |
arg1Of |
involved,in |
R909 |
T1840 |
T1841 |
arg1Of |
proliferation,and |
R91 |
T310 |
T309 |
arg1Of |
type,wild |
R910 |
T1841 |
T1838 |
arg2Of |
and,in |
R9106 |
T13347 |
T13345 |
arg1Of |
type,CCR5 |
R9107 |
T13347 |
T13346 |
arg1Of |
type,wild |
R9108 |
T13347 |
T13348 |
arg1Of |
type,( |
R9109 |
T13347 |
T13351 |
arg1Of |
type,and |
R911 |
T1841 |
T1839 |
arg1Of |
and,the |
R9110 |
T13349 |
T13348 |
arg2Of |
CCR5+/+,( |
R9111 |
T13350 |
T13348 |
arg3Of |
),( |
R9112 |
T13353 |
T13351 |
arg2Of |
knockout,and |
R9113 |
T13353 |
T13352 |
arg1Of |
knockout,CCR5 |
R9114 |
T13353 |
T13354 |
arg1Of |
knockout,( |
R9115 |
T13355 |
T13354 |
arg2Of |
CCR5−/−,( |
R9116 |
T13356 |
T13354 |
arg3Of |
),( |
R9117 |
T13357 |
T13344 |
arg1Of |
mice,The |
R9118 |
T13357 |
T13347 |
arg1Of |
mice,type |
R9119 |
T13357 |
T13353 |
arg1Of |
mice,knockout |
R912 |
T1841 |
T1843 |
arg1Of |
and,of |
R9120 |
T13357 |
T13358 |
arg1Of |
mice,were |
R9121 |
T13357 |
T13359 |
arg2Of |
mice,purchased |
R9122 |
T13359 |
T13358 |
arg2Of |
purchased,were |
R9123 |
T13359 |
T13360 |
arg1Of |
purchased,from |
R9124 |
T13363 |
T13360 |
arg2Of |
Laboratory,from |
R9125 |
T13363 |
T13361 |
arg1Of |
Laboratory,The |
R9126 |
T13363 |
T13362 |
arg1Of |
Laboratory,Jackson |
R9127 |
T13363 |
T13364 |
arg1Of |
Laboratory,( |
R9128 |
T13366 |
T13364 |
arg2Of |
Harbor,( |
R9129 |
T13366 |
T13365 |
arg1Of |
Harbor,Bar |
R913 |
T1842 |
T1841 |
arg2Of |
metastasis,and |
R9130 |
T13366 |
T13367 |
arg1Of |
Harbor,"," |
R9131 |
T13368 |
T13367 |
arg2Of |
Maine,"," |
R9132 |
T13368 |
T13369 |
arg1Of |
Maine,04609 |
R9133 |
T13368 |
T13370 |
arg1Of |
Maine,USA |
R9134 |
T13371 |
T13364 |
arg3Of |
),( |
R9135 |
T13373 |
T13372 |
arg1Of |
mice,The |
R9136 |
T13373 |
T13374 |
arg1Of |
mice,were |
R9137 |
T13373 |
T13375 |
arg2Of |
mice,housed |
R9138 |
T13373 |
T13377 |
arg2Of |
mice,bred |
R9139 |
T13375 |
T13376 |
arg1Of |
housed,and |
R914 |
T1845 |
T1843 |
arg2Of |
cancers,of |
R9140 |
T13376 |
T13374 |
arg2Of |
and,were |
R9141 |
T13376 |
T13378 |
arg1Of |
and,under |
R9142 |
T13377 |
T13376 |
arg2Of |
bred,and |
R9143 |
T13382 |
T13378 |
arg2Of |
conditions,under |
R9144 |
T13382 |
T13379 |
arg1Of |
conditions,specific |
R9145 |
T13382 |
T13380 |
arg1Of |
conditions,pathogen |
R9146 |
T13382 |
T13381 |
arg1Of |
conditions,free |
R9147 |
T13382 |
T13383 |
arg1Of |
conditions,at |
R9148 |
T13388 |
T13383 |
arg2Of |
Center,at |
R9149 |
T13388 |
T13384 |
arg1Of |
Center,the |
R915 |
T1845 |
T1844 |
arg1Of |
cancers,several |
R9150 |
T13388 |
T13385 |
arg1Of |
Center,Laboratory |
R9151 |
T13388 |
T13386 |
arg1Of |
Center,Animal |
R9152 |
T13388 |
T13387 |
arg1Of |
Center,Research |
R9153 |
T13388 |
T13389 |
arg1Of |
Center,of |
R9154 |
T13388 |
T13400 |
modOf |
Center,were |
R9155 |
T13392 |
T13389 |
arg2Of |
University,of |
R9156 |
T13392 |
T13390 |
arg1Of |
University,Chungbuk |
R9157 |
T13392 |
T13391 |
arg1Of |
University,National |
R9158 |
T13396 |
T13394 |
arg1Of |
mice,Korea. |
R9159 |
T13396 |
T13395 |
arg1Of |
mice,The |
R916 |
T1846 |
T1847 |
arg1Of |
Intermediate,and |
R9160 |
T13396 |
T13397 |
arg1Of |
mice,( |
R9161 |
T13396 |
T13400 |
arg1Of |
mice,were |
R9162 |
T13396 |
T13401 |
arg2Of |
mice,maintained |
R9163 |
T13398 |
T13397 |
arg2Of |
n = 4/cage,( |
R9164 |
T13399 |
T13397 |
arg3Of |
),( |
R9165 |
T13401 |
T13393 |
arg1Of |
maintained,"," |
R9166 |
T13401 |
T13400 |
arg2Of |
maintained,were |
R9167 |
T13401 |
T13402 |
arg1Of |
maintained,in |
R9168 |
T13404 |
T13402 |
arg2Of |
room,in |
R9169 |
T13404 |
T13403 |
arg1Of |
room,a |
R917 |
T1848 |
T1847 |
arg2Of |
strong,and |
R9170 |
T13404 |
T13405 |
arg1Of |
room,with |
R9171 |
T13408 |
T13405 |
arg2Of |
temperature,with |
R9172 |
T13408 |
T13406 |
arg1Of |
temperature,a |
R9173 |
T13408 |
T13407 |
arg1Of |
temperature,constant |
R9174 |
T13408 |
T13409 |
arg1Of |
temperature,of |
R9175 |
T13410 |
T13411 |
arg1Of |
22±1°C,"," |
R9176 |
T13411 |
T13418 |
arg1Of |
",",and |
R9177 |
T13413 |
T13411 |
arg2Of |
humidity,"," |
R9178 |
T13413 |
T13412 |
arg1Of |
humidity,relative |
R9179 |
T13413 |
T13414 |
arg1Of |
humidity,of |
R918 |
T1850 |
T1846 |
arg1Of |
expression,Intermediate |
R9180 |
T13416 |
T13414 |
arg2Of |
%,of |
R9181 |
T13416 |
T13415 |
arg1Of |
%,55±10 |
R9182 |
T13418 |
T13417 |
arg1Of |
and,"," |
R9183 |
T13418 |
T13423 |
arg1Of |
and,and |
R9184 |
T13421 |
T13418 |
arg2Of |
cycle,and |
R9185 |
T13421 |
T13419 |
arg1Of |
cycle,12-h |
R9186 |
T13421 |
T13420 |
arg1Of |
cycle,light/dark |
R9187 |
T13423 |
T13409 |
arg2Of |
and,of |
R9188 |
T13423 |
T13422 |
arg1Of |
and,"," |
R9189 |
T13427 |
T13424 |
arg2Of |
chow,fed |
R919 |
T1850 |
T1848 |
arg1Of |
expression,strong |
R9190 |
T13427 |
T13425 |
arg1Of |
chow,standard |
R9191 |
T13427 |
T13426 |
arg1Of |
chow,rodent |
R9192 |
T13427 |
T13428 |
arg1Of |
chow,( |
R9193 |
T13427 |
T13433 |
arg1Of |
chow,and |
R9194 |
T13429 |
T13428 |
arg2Of |
Samyang,( |
R9195 |
T13429 |
T13430 |
arg1Of |
Samyang,"," |
R9196 |
T13431 |
T13430 |
arg2Of |
Korea,"," |
R9197 |
T13432 |
T13428 |
arg3Of |
),( |
R9198 |
T13433 |
T13423 |
arg2Of |
and,and |
R9199 |
T13438 |
T13433 |
arg2Of |
libitum,and |
R92 |
T310 |
T311 |
arg1Of |
type,( |
R920 |
T1850 |
T1849 |
arg1Of |
expression,CCR5 |
R9200 |
T13438 |
T13434 |
arg2Of |
libitum,purified |
R9201 |
T13438 |
T13435 |
arg1Of |
libitum,tap |
R9202 |
T13438 |
T13436 |
arg1Of |
libitum,water |
R9203 |
T13438 |
T13437 |
arg1Of |
libitum,ad |
R9204 |
T13441 |
T13440 |
arg1Of |
mice,CCR5+/+ |
R9205 |
T13441 |
T13442 |
arg1Of |
mice,( |
R9206 |
T13441 |
T13445 |
arg1Of |
mice,and |
R9207 |
T13443 |
T13442 |
arg2Of |
n = 20,( |
R9208 |
T13444 |
T13442 |
arg3Of |
),( |
R9209 |
T13445 |
T13439 |
arg1Of |
and,The |
R921 |
T1850 |
T1851 |
arg1Of |
expression,is |
R9210 |
T13445 |
T13456 |
arg1Of |
and,had |
R9211 |
T13445 |
T13457 |
arg1Of |
and,matched |
R9212 |
T13447 |
T13445 |
arg2Of |
mice,and |
R9213 |
T13447 |
T13446 |
arg1Of |
mice,CCR5−/− |
R9214 |
T13447 |
T13448 |
arg1Of |
mice,( |
R9215 |
T13447 |
T13451 |
arg1Of |
mice,"," |
R9216 |
T13447 |
T13452 |
arg1Of |
mice,that |
R9217 |
T13447 |
T13453 |
arg1Of |
mice,were |
R9218 |
T13447 |
T13454 |
arg2Of |
mice,used |
R9219 |
T13449 |
T13448 |
arg2Of |
n = 20,( |
R922 |
T1850 |
T1853 |
arg2Of |
expression,associated |
R9220 |
T13450 |
T13448 |
arg3Of |
),( |
R9221 |
T13454 |
T13453 |
arg2Of |
used,were |
R9222 |
T13457 |
T13455 |
arg1Of |
matched,"," |
R9223 |
T13457 |
T13456 |
arg2Of |
matched,had |
R9224 |
T13458 |
T13459 |
arg1Of |
ages,( |
R9225 |
T13458 |
T13464 |
arg1Of |
ages,and |
R9226 |
T13461 |
T13459 |
arg2Of |
weeks,( |
R9227 |
T13461 |
T13460 |
arg1Of |
weeks,10–11 |
R9228 |
T13461 |
T13462 |
arg1Of |
weeks,old |
R9229 |
T13463 |
T13459 |
arg3Of |
),( |
R923 |
T1853 |
T1851 |
arg2Of |
associated,is |
R9230 |
T13464 |
T13457 |
arg2Of |
and,matched |
R9231 |
T13465 |
T13464 |
arg2Of |
weights,and |
R9232 |
T13465 |
T13466 |
arg1Of |
weights,( |
R9233 |
T13468 |
T13466 |
arg2Of |
g,( |
R9234 |
T13468 |
T13467 |
arg1Of |
g,16–19 |
R9235 |
T13469 |
T13466 |
arg3Of |
),( |
R9236 |
T13471 |
T13470 |
arg1Of |
mice,Control |
R9237 |
T13471 |
T13472 |
arg1Of |
mice,( |
R9238 |
T13471 |
T13475 |
arg1Of |
mice,were |
R9239 |
T13473 |
T13472 |
arg2Of |
B6129PF2/J,( |
R924 |
T1853 |
T1852 |
arg1Of |
associated,significantly |
R9240 |
T13474 |
T13472 |
arg3Of |
),( |
R9241 |
T13478 |
T13475 |
arg2Of |
mice,were |
R9242 |
T13478 |
T13476 |
arg1Of |
mice,F2 |
R9243 |
T13478 |
T13477 |
arg1Of |
mice,hybrid |
R9244 |
T13478 |
T13479 |
arg1Of |
mice,from |
R9245 |
T13481 |
T13482 |
arg1Of |
C57BL/6J-AW-J,and |
R9246 |
T13483 |
T13482 |
arg2Of |
129P3/J,and |
R9247 |
T13485 |
T13479 |
arg2Of |
strains,from |
R9248 |
T13485 |
T13480 |
arg1Of |
strains,the |
R9249 |
T13485 |
T13481 |
arg1Of |
strains,C57BL/6J-AW-J |
R925 |
T1853 |
T1854 |
arg1Of |
associated,with |
R9250 |
T13485 |
T13483 |
arg1Of |
strains,129P3/J |
R9251 |
T13485 |
T13484 |
arg1Of |
strains,parental |
R9252 |
T13487 |
T13486 |
arg1Of |
mice,CCR5 |
R9253 |
T13487 |
T13488 |
arg1Of |
mice,( |
R9254 |
T13487 |
T13493 |
arg1Of |
mice,have |
R9255 |
T13489 |
T13488 |
arg2Of |
B6,( |
R9256 |
T13489 |
T13490 |
arg1Of |
B6,"," |
R9257 |
T13491 |
T13490 |
arg2Of |
129P2-Ccr5tm1Kuz/J,"," |
R9258 |
T13492 |
T13488 |
arg3Of |
),( |
R9259 |
T13497 |
T13493 |
arg2Of |
region,have |
R926 |
T1853 |
T1890 |
arg1Of |
associated,[ |
R9260 |
T13497 |
T13494 |
arg1Of |
region,the |
R9261 |
T13497 |
T13495 |
arg1Of |
region,entire |
R9262 |
T13497 |
T13496 |
arg1Of |
region,coding |
R9263 |
T13497 |
T13498 |
arg1Of |
region,of |
R9264 |
T13501 |
T13498 |
arg2Of |
gene,of |
R9265 |
T13501 |
T13499 |
arg1Of |
gene,the |
R9266 |
T13501 |
T13500 |
arg1Of |
gene,CCR5 |
R9267 |
T13501 |
T13502 |
arg2Of |
gene,deleted |
R9268 |
T13501 |
T13507 |
arg1Of |
gene,"," |
R9269 |
T13502 |
T13503 |
arg1Of |
deleted,from |
R927 |
T1856 |
T1855 |
arg1Of |
development,nonmetastatic |
R9270 |
T13506 |
T13503 |
arg2Of |
strains,from |
R9271 |
T13506 |
T13504 |
arg1Of |
strains,the |
R9272 |
T13506 |
T13505 |
arg1Of |
strains,parental |
R9273 |
T13508 |
T13507 |
arg2Of |
B6,"," |
R9274 |
T13508 |
T13509 |
arg1Of |
B6,; |
R9275 |
T13510 |
T13511 |
arg1Of |
129P2-Ccr5tm1kuz,and |
R9276 |
T13511 |
T13509 |
arg2Of |
and,; |
R9277 |
T13511 |
T13513 |
arg1Of |
and,; |
R9278 |
T13512 |
T13511 |
arg2Of |
B6,and |
R9279 |
T13514 |
T13513 |
arg2Of |
129P2-Cmkbr5tm1Kuz,; |
R928 |
T1856 |
T1857 |
arg1Of |
development,of |
R929 |
T1856 |
T1884 |
arg1Of |
development,as |
R93 |
T312 |
T311 |
arg2Of |
CCR5+/+,( |
R930 |
T1859 |
T1858 |
arg1Of |
cancer,colorectal |
R931 |
T1859 |
T1860 |
arg1Of |
cancer,[ |
R932 |
T1859 |
T1863 |
arg1Of |
cancer,"," |
R933 |
T1861 |
T1860 |
arg2Of |
2,[ |
R934 |
T1862 |
T1860 |
arg3Of |
],[ |
R935 |
T1863 |
T1868 |
arg1Of |
",","," |
R936 |
T1864 |
T1863 |
arg2Of |
melanoma,"," |
R937 |
T1864 |
T1865 |
arg1Of |
melanoma,[ |
R938 |
T1866 |
T1865 |
arg2Of |
3,[ |
R939 |
T1867 |
T1865 |
arg3Of |
],[ |
R94 |
T313 |
T311 |
arg3Of |
),( |
R940 |
T1868 |
T1873 |
arg1Of |
",","," |
R941 |
T1869 |
T1868 |
arg2Of |
hepatoma,"," |
R942 |
T1869 |
T1870 |
arg1Of |
hepatoma,[ |
R943 |
T1871 |
T1870 |
arg2Of |
4,[ |
R944 |
T1872 |
T1870 |
arg3Of |
],[ |
R945 |
T1873 |
T1875 |
arg1Of |
",","," |
R946 |
T1874 |
T1873 |
arg2Of |
glioblastoma,"," |
R947 |
T1875 |
T1857 |
arg2Of |
",",of |
R948 |
T1877 |
T1875 |
arg2Of |
lymphoma,"," |
R949 |
T1877 |
T1876 |
arg1Of |
lymphoma,Hodgkin |
R9498 |
T13815 |
T13814 |
arg1Of |
Inoculation,Tumor |
R9499 |
T13815 |
T13816 |
arg1Of |
Inoculation,and |
R95 |
T314 |
T308 |
arg2Of |
mice,and |
R950 |
T1877 |
T1878 |
arg1Of |
lymphoma,[ |
R9500 |
T13818 |
T13816 |
arg2Of |
Monitoring,and |
R9501 |
T13818 |
T13817 |
arg1Of |
Monitoring,Tumor |
R9502 |
T13821 |
T13819 |
arg1Of |
cells,B16 |
R9503 |
T13821 |
T13820 |
arg1Of |
cells,melanoma |
R9504 |
T13821 |
T13822 |
arg1Of |
cells,were |
R9505 |
T13821 |
T13823 |
arg2Of |
cells,injected |
R9506 |
T13823 |
T13822 |
arg2Of |
injected,were |
R9507 |
T13823 |
T13824 |
arg1Of |
injected,subcutaneously |
R9508 |
T13823 |
T13825 |
arg1Of |
injected,[ |
R9509 |
T13823 |
T13840 |
modOf |
injected,using |
R951 |
T1879 |
T1878 |
arg2Of |
5,[ |
R9510 |
T13828 |
T13825 |
arg2Of |
cells,[ |
R9511 |
T13828 |
T13826 |
arg1Of |
cells,5×105 |
R9512 |
T13828 |
T13827 |
arg1Of |
cells,tumor |
R9513 |
T13828 |
T13829 |
arg1Of |
cells,in |
R9514 |
T13830 |
T13831 |
arg1Of |
0.1,ml |
R9515 |
T13832 |
T13829 |
arg2Of |
Phosphate,in |
R9516 |
T13832 |
T13830 |
arg1Of |
Phosphate,0.1 |
R9517 |
T13832 |
T13833 |
arg2Of |
Phosphate,buffered |
R9518 |
T13832 |
T13838 |
arg1Of |
Phosphate,/animal |
R9519 |
T13834 |
T13833 |
arg3Of |
saline,buffered |
R952 |
T1880 |
T1878 |
arg3Of |
],[ |
R9520 |
T13834 |
T13835 |
arg1Of |
saline,( |
R9521 |
T13836 |
T13835 |
arg2Of |
PBS,( |
R9522 |
T13837 |
T13835 |
arg3Of |
),( |
R9523 |
T13839 |
T13825 |
arg3Of |
],[ |
R9524 |
T13844 |
T13840 |
arg2Of |
needle,using |
R9525 |
T13844 |
T13841 |
arg1Of |
needle,a |
R9526 |
T13844 |
T13842 |
arg1Of |
needle,27 |
R9527 |
T13844 |
T13843 |
arg1Of |
needle,G |
R9528 |
T13844 |
T13845 |
arg1Of |
needle,into |
R9529 |
T13848 |
T13845 |
arg2Of |
flanks,into |
R953 |
T1884 |
T1854 |
arg2Of |
as,with |
R9530 |
T13848 |
T13846 |
arg1Of |
flanks,the |
R9531 |
T13848 |
T13847 |
arg1Of |
flanks,right-lower |
R9532 |
T13848 |
T13849 |
arg1Of |
flanks,of |
R9533 |
T13848 |
T13853 |
arg1Of |
flanks,as |
R9534 |
T13852 |
T13849 |
arg2Of |
mice,of |
R9535 |
T13852 |
T13850 |
arg1Of |
mice,the |
R9536 |
T13852 |
T13851 |
arg1Of |
mice,carrier |
R9537 |
T13855 |
T13854 |
arg1Of |
described,previously |
R9538 |
T13857 |
T13853 |
arg2Of |
54,as |
R9539 |
T13857 |
T13855 |
arg1Of |
54,described |
R954 |
T1884 |
T1881 |
arg1Of |
as,"," |
R9540 |
T13857 |
T13856 |
arg2Of |
54,[ |
R9541 |
T13858 |
T13856 |
arg3Of |
],[ |
R9542 |
T13861 |
T13860 |
arg1Of |
weights,body |
R9543 |
T13861 |
T13862 |
arg1Of |
weights,and |
R9544 |
T13862 |
T13859 |
arg1Of |
and,The |
R9545 |
T13862 |
T13865 |
arg1Of |
and,of |
R9546 |
T13862 |
T13868 |
arg1Of |
and,were |
R9547 |
T13862 |
T13869 |
arg2Of |
and,monitored |
R9548 |
T13864 |
T13862 |
arg2Of |
volumes,and |
R9549 |
T13864 |
T13863 |
arg1Of |
volumes,tumor |
R955 |
T1884 |
T1882 |
arg1Of |
as,as |
R9550 |
T13867 |
T13865 |
arg2Of |
animals,of |
R9551 |
T13867 |
T13866 |
arg1Of |
animals,the |
R9552 |
T13869 |
T13868 |
arg2Of |
monitored,were |
R9553 |
T13869 |
T13871 |
arg1Of |
monitored,weekly |
R9554 |
T13871 |
T13870 |
arg1Of |
weekly,twice |
R9555 |
T13874 |
T13872 |
arg1Of |
volumes,The |
R9556 |
T13874 |
T13873 |
arg1Of |
volumes,tumor |
R9557 |
T13874 |
T13875 |
arg1Of |
volumes,were |
R9558 |
T13874 |
T13876 |
arg2Of |
volumes,measured |
R9559 |
T13874 |
T13881 |
arg2Of |
volumes,calculated |
R956 |
T1884 |
T1883 |
arg1Of |
as,well |
R9560 |
T13876 |
T13875 |
arg2Of |
measured,were |
R9561 |
T13876 |
T13877 |
arg1Of |
measured,with |
R9562 |
T13876 |
T13880 |
arg1Of |
measured,and |
R9563 |
T13879 |
T13877 |
arg2Of |
calipers,with |
R9564 |
T13879 |
T13878 |
arg1Of |
calipers,Vernier |
R9565 |
T13881 |
T13880 |
arg2Of |
calculated,and |
R9566 |
T13881 |
T13882 |
modOf |
calculated,using |
R9567 |
T13885 |
T13882 |
arg2Of |
formula,using |
R9568 |
T13885 |
T13883 |
arg1Of |
formula,the |
R9569 |
T13885 |
T13884 |
arg1Of |
formula,following |
R957 |
T1889 |
T1884 |
arg2Of |
cells,as |
R9570 |
T13885 |
T13886 |
arg1Of |
formula,: |
R9571 |
T13888 |
T13887 |
arg2Of |
A×B2,( |
R9572 |
T13889 |
T13887 |
arg3Of |
),( |
R9573 |
T13890 |
T13886 |
arg2Of |
/2,: |
R9574 |
T13890 |
T13887 |
arg1Of |
/2,( |
R9575 |
T13890 |
T13891 |
arg1Of |
/2,"," |
R9576 |
T13890 |
T13892 |
arg1Of |
/2,where |
R9577 |
T13893 |
T13894 |
arg1Of |
A,is |
R9578 |
T13893 |
T13896 |
arg1Of |
A,larger |
R9579 |
T13894 |
T13897 |
arg1Of |
is,and |
R958 |
T1889 |
T1885 |
arg1Of |
cells,oral |
R9580 |
T13896 |
T13894 |
arg2Of |
larger,is |
R9581 |
T13896 |
T13895 |
arg1Of |
larger,the |
R9582 |
T13897 |
T13892 |
arg2Of |
and,where |
R9583 |
T13898 |
T13899 |
arg1Of |
B,is |
R9584 |
T13899 |
T13897 |
arg2Of |
is,and |
R9585 |
T13901 |
T13899 |
arg2Of |
smaller,is |
R9586 |
T13901 |
T13900 |
arg1Of |
smaller,the |
R9587 |
T13901 |
T13902 |
arg1Of |
smaller,of |
R9588 |
T13905 |
T13902 |
arg2Of |
dimensions,of |
R9589 |
T13905 |
T13903 |
arg1Of |
dimensions,the |
R959 |
T1889 |
T1886 |
arg1Of |
cells,and |
R9590 |
T13905 |
T13904 |
arg1Of |
dimensions,two |
R9591 |
T13908 |
T13906 |
arg2Of |
end,At |
R9592 |
T13908 |
T13907 |
arg1Of |
end,the |
R9593 |
T13908 |
T13909 |
arg1Of |
end,of |
R9594 |
T13911 |
T13909 |
arg2Of |
experiment,of |
R9595 |
T13911 |
T13910 |
arg1Of |
experiment,the |
R9596 |
T13914 |
T13913 |
arg1Of |
animals,the |
R9597 |
T13914 |
T13915 |
arg1Of |
animals,were |
R9598 |
T13914 |
T13916 |
arg2Of |
animals,sacrificed |
R9599 |
T13916 |
T13906 |
arg1Of |
sacrificed,At |
R96 |
T314 |
T310 |
arg1Of |
mice,type |
R960 |
T1889 |
T1887 |
arg1Of |
cells,prostate |
R9600 |
T13916 |
T13912 |
arg1Of |
sacrificed,"," |
R9601 |
T13916 |
T13915 |
arg2Of |
sacrificed,were |
R9602 |
T13918 |
T13917 |
arg1Of |
tumors,The |
R9603 |
T13918 |
T13919 |
arg1Of |
tumors,were |
R9604 |
T13918 |
T13920 |
arg2Of |
tumors,separated |
R9605 |
T13920 |
T13919 |
arg2Of |
separated,were |
R9606 |
T13920 |
T13921 |
arg1Of |
separated,from |
R9607 |
T13924 |
T13925 |
arg1Of |
muscles,and |
R9608 |
T13925 |
T13921 |
arg2Of |
and,from |
R9609 |
T13925 |
T13922 |
arg1Of |
and,the |
R961 |
T1889 |
T1888 |
arg1Of |
cells,cancer |
R9610 |
T13925 |
T13923 |
arg1Of |
and,surrounding |
R9611 |
T13926 |
T13925 |
arg2Of |
dermis,and |
R962 |
T1891 |
T1890 |
arg2Of |
6,[ |
R963 |
T1892 |
T1890 |
arg3Of |
],[ |
R964 |
T1894 |
T1893 |
arg1Of |
production,Local |
R965 |
T1894 |
T1895 |
arg1Of |
production,of |
R966 |
T1894 |
T1898 |
arg1Of |
production,is |
R967 |
T1894 |
T1900 |
arg1Of |
production,important |
R968 |
T1894 |
T1913 |
arg1Of |
production,correlates |
R969 |
T1897 |
T1895 |
arg2Of |
CCL5,of |
R97 |
T316 |
T315 |
arg1Of |
mice,CCR5−/− |
R970 |
T1897 |
T1896 |
arg1Of |
CCL5,the |
R971 |
T1898 |
T1899 |
arg1Of |
is,also |
R972 |
T1898 |
T1911 |
arg1Of |
is,and |
R973 |
T1900 |
T1898 |
arg2Of |
important,is |
R9736 |
T14103 |
T14102 |
arg1Of |
Blotting,Western |
R9737 |
T14105 |
T14104 |
arg1Of |
tissues,Tumor |
R9738 |
T14105 |
T14106 |
arg1Of |
tissues,were |
R9739 |
T14105 |
T14107 |
arg2Of |
tissues,homogenized |
R974 |
T1900 |
T1901 |
arg1Of |
important,in |
R9740 |
T14105 |
T14124 |
arg2Of |
tissues,lysed |
R9741 |
T14107 |
T14108 |
arg1Of |
homogenized,with |
R9742 |
T14107 |
T14123 |
arg1Of |
homogenized,and |
R9743 |
T14111 |
T14108 |
arg2Of |
solution,with |
R9744 |
T14111 |
T14109 |
arg1Of |
solution,protein |
R9745 |
T14111 |
T14110 |
arg1Of |
solution,extraction |
R9746 |
T14111 |
T14112 |
arg1Of |
solution,( |
R9747 |
T14113 |
T14114 |
arg1Of |
PRO-PREPTM,"," |
R9748 |
T14113 |
T14117 |
arg1Of |
PRO-PREPTM,"," |
R9749 |
T14116 |
T14114 |
arg2Of |
Biotechnology,"," |
R975 |
T1903 |
T1901 |
arg2Of |
progression,in |
R9750 |
T14116 |
T14115 |
arg1Of |
Biotechnology,Intron |
R9751 |
T14117 |
T14112 |
arg2Of |
",",( |
R9752 |
T14118 |
T14117 |
arg2Of |
Seoul,"," |
R9753 |
T14118 |
T14119 |
arg1Of |
Seoul,"," |
R9754 |
T14120 |
T14119 |
arg2Of |
Korea,"," |
R9755 |
T14121 |
T14112 |
arg3Of |
),( |
R9756 |
T14123 |
T14106 |
arg2Of |
and,were |
R9757 |
T14123 |
T14122 |
arg1Of |
and,"," |
R9758 |
T14124 |
T14123 |
arg2Of |
lysed,and |
R9759 |
T14128 |
T14124 |
arg1Of |
incubation,lysed |
R976 |
T1903 |
T1902 |
arg1Of |
progression,the |
R9760 |
T14128 |
T14125 |
arg2Of |
incubation,by |
R9761 |
T14128 |
T14126 |
arg1Of |
incubation,60 |
R9762 |
T14128 |
T14127 |
arg1Of |
incubation,min |
R9763 |
T14128 |
T14129 |
arg1Of |
incubation,on |
R9764 |
T14130 |
T14129 |
arg2Of |
ice,on |
R9765 |
T14133 |
T14131 |
arg1Of |
lysate,The |
R9766 |
T14133 |
T14132 |
arg1Of |
lysate,tissue |
R9767 |
T14133 |
T14134 |
arg2Of |
lysate,centrifuged |
R9768 |
T14133 |
T14151 |
arg1Of |
lysate,were |
R9769 |
T14133 |
T14152 |
arg2Of |
lysate,separated |
R977 |
T1903 |
T1904 |
arg1Of |
progression,of |
R9770 |
T14133 |
T14162 |
arg2Of |
lysate,transferred |
R9771 |
T14134 |
T14135 |
arg1Of |
centrifuged,at |
R9772 |
T14134 |
T14138 |
arg1Of |
centrifuged,for |
R9773 |
T14137 |
T14135 |
arg2Of |
rpm,at |
R9774 |
T14137 |
T14136 |
arg1Of |
rpm,"15,000" |
R9775 |
T14140 |
T14138 |
arg2Of |
min,for |
R9776 |
T14140 |
T14139 |
arg1Of |
min,15 |
R9777 |
T14140 |
T14141 |
arg1Of |
min,at |
R9778 |
T14143 |
T14142 |
arg1Of |
Equal,4°C. |
R9779 |
T14144 |
T14141 |
arg2Of |
amounts,at |
R978 |
T1906 |
T1904 |
arg2Of |
cancer,of |
R9780 |
T14144 |
T14143 |
arg1Of |
amounts,Equal |
R9781 |
T14144 |
T14145 |
arg1Of |
amounts,of |
R9782 |
T14146 |
T14145 |
arg2Of |
proteins,of |
R9783 |
T14146 |
T14147 |
arg1Of |
proteins,( |
R9784 |
T14149 |
T14147 |
arg2Of |
µg,( |
R9785 |
T14149 |
T14148 |
arg1Of |
µg,40 |
R9786 |
T14150 |
T14147 |
arg3Of |
),( |
R9787 |
T14152 |
T14153 |
arg1Of |
separated,on |
R9788 |
T14152 |
T14160 |
arg1Of |
separated,and |
R9789 |
T14158 |
T14153 |
arg2Of |
gel,on |
R979 |
T1906 |
T1905 |
arg1Of |
cancer,breast |
R9790 |
T14158 |
T14154 |
arg1Of |
gel,a |
R9791 |
T14158 |
T14155 |
arg1Of |
gel,SDS/12 |
R9792 |
T14158 |
T14156 |
arg1Of |
gel,% |
R9793 |
T14158 |
T14157 |
arg1Of |
gel,-polyacrylamide |
R9794 |
T14160 |
T14151 |
arg2Of |
and,were |
R9795 |
T14160 |
T14159 |
arg1Of |
and,"," |
R9796 |
T14162 |
T14160 |
arg2Of |
transferred,and |
R9797 |
T14162 |
T14161 |
arg1Of |
transferred,then |
R9798 |
T14162 |
T14163 |
arg1Of |
transferred,to |
R9799 |
T14168 |
T14167 |
arg2Of |
PVDF,( |
R98 |
T316 |
T317 |
arg1Of |
mice,showed |
R980 |
T1906 |
T1907 |
arg1Of |
cancer,[ |
R9800 |
T14169 |
T14167 |
arg3Of |
),( |
R9801 |
T14170 |
T14163 |
arg2Of |
membrane,to |
R9802 |
T14170 |
T14164 |
arg1Of |
membrane,a |
R9803 |
T14170 |
T14165 |
arg1Of |
membrane,polyvinylidene |
R9804 |
T14170 |
T14166 |
arg1Of |
membrane,difluoride |
R9805 |
T14170 |
T14167 |
arg1Of |
membrane,( |
R9806 |
T14170 |
T14171 |
arg1Of |
membrane,( |
R9807 |
T14173 |
T14172 |
arg1Of |
Water,GE |
R9808 |
T14173 |
T14174 |
arg1Of |
Water,and |
R9809 |
T14175 |
T14174 |
arg2Of |
Process,and |
R981 |
T1908 |
T1907 |
arg2Of |
7,[ |
R9810 |
T14176 |
T14171 |
arg2Of |
technologies,( |
R9811 |
T14176 |
T14173 |
arg1Of |
technologies,Water |
R9812 |
T14176 |
T14175 |
arg1Of |
technologies,Process |
R9813 |
T14176 |
T14177 |
arg1Of |
technologies,"," |
R9814 |
T14176 |
T14181 |
arg1Of |
technologies,"," |
R9815 |
T14176 |
T14182 |
arg1Of |
technologies,USA |
R9816 |
T14178 |
T14177 |
arg2Of |
Trevose,"," |
R9817 |
T14178 |
T14179 |
arg1Of |
Trevose,"," |
R9818 |
T14180 |
T14179 |
arg2Of |
PA,"," |
R9819 |
T14183 |
T14171 |
arg3Of |
),( |
R982 |
T1909 |
T1907 |
arg3Of |
],[ |
R9820 |
T14184 |
T14185 |
arg1Of |
Blots,were |
R9821 |
T14184 |
T14186 |
arg2Of |
Blots,blocked |
R9822 |
T14186 |
T14185 |
arg2Of |
blocked,were |
R9823 |
T14186 |
T14187 |
arg1Of |
blocked,for |
R9824 |
T14186 |
T14190 |
arg1Of |
blocked,at |
R9825 |
T14186 |
T14193 |
arg1Of |
blocked,with |
R9826 |
T14189 |
T14187 |
arg2Of |
h,for |
R9827 |
T14189 |
T14188 |
arg1Of |
h,1 |
R9828 |
T14192 |
T14190 |
arg2Of |
temperature,at |
R9829 |
T14192 |
T14191 |
arg1Of |
temperature,room |
R983 |
T1911 |
T1910 |
arg1Of |
and,"," |
R9830 |
T14195 |
T14194 |
arg1Of |
%,5 |
R9831 |
T14197 |
T14196 |
arg2Of |
w/v,( |
R9832 |
T14198 |
T14196 |
arg3Of |
),( |
R9833 |
T14201 |
T14193 |
arg2Of |
milk,with |
R9834 |
T14201 |
T14195 |
arg1Of |
milk,% |
R9835 |
T14201 |
T14196 |
arg1Of |
milk,( |
R9836 |
T14201 |
T14199 |
arg1Of |
milk,non-fat |
R9837 |
T14201 |
T14200 |
arg2Of |
milk,dried |
R9838 |
T14201 |
T14202 |
arg1Of |
milk,in |
R9839 |
T14201 |
T14208 |
arg1Of |
milk,: |
R984 |
T1913 |
T1911 |
arg2Of |
correlates,and |
R9840 |
T14207 |
T14202 |
arg2Of |
TBST,in |
R9841 |
T14207 |
T14203 |
arg1Of |
TBST,Tris-Buffered |
R9842 |
T14207 |
T14204 |
arg1Of |
TBST,Saline |
R9843 |
T14207 |
T14205 |
arg1Of |
TBST,Tween-20 |
R9844 |
T14207 |
T14206 |
arg1Of |
TBST,[ |
R9845 |
T14209 |
T14210 |
arg1Of |
10,mM |
R9846 |
T14211 |
T14209 |
arg1Of |
Tris,10 |
R9847 |
T14211 |
T14212 |
arg1Of |
Tris,( |
R9848 |
T14211 |
T14216 |
arg1Of |
Tris,and |
R9849 |
T14213 |
T14212 |
arg2Of |
pH,( |
R985 |
T1913 |
T1912 |
arg1Of |
correlates,also |
R9850 |
T14213 |
T14214 |
arg1Of |
pH,8.0 |
R9851 |
T14215 |
T14212 |
arg3Of |
),( |
R9852 |
T14216 |
T14224 |
arg1Of |
and,Tween-20 |
R9853 |
T14216 |
T14225 |
arg1Of |
and,] |
R9854 |
T14217 |
T14218 |
arg1Of |
150,mM |
R9855 |
T14220 |
T14216 |
arg2Of |
solution,and |
R9856 |
T14220 |
T14217 |
arg1Of |
solution,150 |
R9857 |
T14220 |
T14219 |
arg1Of |
solution,NaCl |
R9858 |
T14220 |
T14221 |
arg1Of |
solution,containing |
R9859 |
T14223 |
T14221 |
arg2Of |
%,containing |
R986 |
T1913 |
T1914 |
arg1Of |
correlates,with |
R9860 |
T14223 |
T14222 |
arg1Of |
%,0.05 |
R9861 |
T14229 |
T14226 |
arg2Of |
washing,After |
R9862 |
T14229 |
T14227 |
arg1Of |
washing,a |
R9863 |
T14229 |
T14228 |
arg1Of |
washing,short |
R9864 |
T14229 |
T14230 |
arg1Of |
washing,in |
R9865 |
T14231 |
T14230 |
arg2Of |
TBST,in |
R9866 |
T14234 |
T14233 |
arg1Of |
membranes,the |
R9867 |
T14234 |
T14235 |
arg1Of |
membranes,were |
R9868 |
T14234 |
T14236 |
arg2Of |
membranes,immunoblotted |
R9869 |
T14236 |
T14226 |
arg1Of |
immunoblotted,After |
R987 |
T1913 |
T1917 |
arg1Of |
correlates,[ |
R9870 |
T14236 |
T14232 |
arg1Of |
immunoblotted,"," |
R9871 |
T14236 |
T14235 |
arg2Of |
immunoblotted,were |
R9872 |
T14236 |
T14237 |
arg1Of |
immunoblotted,with |
R9873 |
T14241 |
T14237 |
arg2Of |
antibodies,with |
R9874 |
T14241 |
T14238 |
arg1Of |
antibodies,the |
R9875 |
T14241 |
T14239 |
arg1Of |
antibodies,following |
R9876 |
T14241 |
T14240 |
arg1Of |
antibodies,primary |
R9877 |
T14241 |
T14242 |
arg1Of |
antibodies,: |
R9878 |
T14245 |
T14243 |
arg1Of |
antibodies,mouse |
R9879 |
T14245 |
T14244 |
arg1Of |
antibodies,monoclonal |
R988 |
T1916 |
T1914 |
arg2Of |
prognosis,with |
R9880 |
T14245 |
T14246 |
arg2Of |
antibodies,directed |
R9881 |
T14245 |
T14251 |
arg1Of |
antibodies,( |
R9882 |
T14245 |
T14264 |
arg1Of |
antibodies,"," |
R9883 |
T14246 |
T14247 |
arg1Of |
directed,against |
R9884 |
T14248 |
T14249 |
arg1Of |
p65,and |
R9885 |
T14249 |
T14247 |
arg2Of |
and,against |
R9886 |
T14250 |
T14249 |
arg2Of |
p50,and |
R9887 |
T14253 |
T14251 |
arg2Of |
dilutions,( |
R9888 |
T14253 |
T14252 |
arg1Of |
dilutions,1∶500 |
R9889 |
T14253 |
T14254 |
arg1Of |
dilutions,; |
R989 |
T1916 |
T1915 |
arg1Of |
prognosis,poor |
R9890 |
T14253 |
T14261 |
arg1Of |
dilutions,"," |
R9891 |
T14253 |
T14262 |
arg1Of |
dilutions,CA |
R9892 |
T14257 |
T14254 |
arg2Of |
Biotechnology,; |
R9893 |
T14257 |
T14255 |
arg1Of |
Biotechnology,Santa |
R9894 |
T14257 |
T14256 |
arg1Of |
Biotechnology,Cruz |
R9895 |
T14257 |
T14258 |
arg1Of |
Biotechnology,"," |
R9896 |
T14260 |
T14258 |
arg2Of |
Cruz,"," |
R9897 |
T14260 |
T14259 |
arg1Of |
Cruz,Santa |
R9898 |
T14263 |
T14251 |
arg3Of |
),( |
R9899 |
T14264 |
T14242 |
arg2Of |
",",: |
R99 |
T316 |
T330 |
arg1Of |
mice,compared |
R990 |
T1918 |
T1917 |
arg2Of |
8,[ |
R9900 |
T14264 |
T14268 |
arg2Of |
",",directed |
R9901 |
T14264 |
T14291 |
arg1Of |
",",( |
R9902 |
T14267 |
T14264 |
arg2Of |
antibodies,"," |
R9903 |
T14267 |
T14265 |
arg1Of |
antibodies,rabbit |
R9904 |
T14267 |
T14266 |
arg1Of |
antibodies,polyclonal |
R9905 |
T14268 |
T14269 |
arg1Of |
directed,against |
R9906 |
T14268 |
T14283 |
arg1Of |
directed,against |
R9907 |
T14269 |
T14282 |
arg1Of |
against,and |
R9908 |
T14270 |
T14271 |
arg1Of |
Bax,and |
R9909 |
T14271 |
T14269 |
arg2Of |
and,against |
R991 |
T1919 |
T1917 |
arg3Of |
],[ |
R9910 |
T14272 |
T14271 |
arg2Of |
PARP,and |
R9911 |
T14272 |
T14273 |
arg1Of |
PARP,( |
R9912 |
T14275 |
T14273 |
arg2Of |
dilutions,( |
R9913 |
T14275 |
T14274 |
arg1Of |
dilutions,1∶500 |
R9914 |
T14275 |
T14276 |
arg1Of |
dilutions,; |
R9915 |
T14279 |
T14276 |
arg2Of |
Biotechnology,; |
R9916 |
T14279 |
T14277 |
arg1Of |
Biotechnology,Santa |
R9917 |
T14279 |
T14278 |
arg1Of |
Biotechnology,Cruz |
R9918 |
T14280 |
T14273 |
arg3Of |
),( |
R9919 |
T14282 |
T14281 |
arg1Of |
and,"," |
R992 |
T1923 |
T1922 |
arg1Of |
disruption,CCR5 |
R9920 |
T14283 |
T14282 |
arg2Of |
against,and |
R9921 |
T14284 |
T14285 |
arg1Of |
caspase-3,"," |
R9922 |
T14285 |
T14287 |
arg1Of |
",","," |
R9923 |
T14286 |
T14285 |
arg2Of |
caspase-9,"," |
R9924 |
T14287 |
T14289 |
arg1Of |
",",and |
R9925 |
T14288 |
T14287 |
arg2Of |
Bcl-2,"," |
R9926 |
T14289 |
T14283 |
arg2Of |
and,against |
R9927 |
T14290 |
T14289 |
arg2Of |
c-IAP-1,and |
R9928 |
T14293 |
T14291 |
arg2Of |
dilutions,( |
R9929 |
T14293 |
T14292 |
arg1Of |
dilutions,1∶1000 |
R993 |
T1923 |
T1924 |
arg1Of |
disruption,has |
R9930 |
T14293 |
T14294 |
arg1Of |
dilutions,; |
R9931 |
T14293 |
T14300 |
arg1Of |
dilutions,"," |
R9932 |
T14293 |
T14301 |
arg1Of |
dilutions,MA |
R9933 |
T14297 |
T14295 |
arg1Of |
Technology,Cell |
R9934 |
T14297 |
T14296 |
arg1Of |
Technology,Signaling |
R9935 |
T14297 |
T14298 |
arg1Of |
Technology,"," |
R9936 |
T14298 |
T14294 |
arg2Of |
",",; |
R9937 |
T14299 |
T14298 |
arg2Of |
Beverly,"," |
R9938 |
T14302 |
T14291 |
arg3Of |
),( |
R9939 |
T14304 |
T14303 |
arg1Of |
blots,The |
R994 |
T1923 |
T1925 |
arg1Of |
disruption,been |
R9940 |
T14304 |
T14305 |
arg1Of |
blots,were |
R9941 |
T14304 |
T14306 |
arg2Of |
blots,incubated |
R9942 |
T14306 |
T14305 |
arg2Of |
incubated,were |
R9943 |
T14306 |
T14307 |
arg1Of |
incubated,with |
R9944 |
T14311 |
T14310 |
arg1Of |
peroxidase-conjugated,horseradish |
R9945 |
T14312 |
T14313 |
arg1Of |
anti-rabbit,or |
R9946 |
T14314 |
T14313 |
arg2Of |
anti-mouse,or |
R9947 |
T14315 |
T14307 |
arg2Of |
IgG,with |
R9948 |
T14315 |
T14308 |
arg1Of |
IgG,the |
R9949 |
T14315 |
T14309 |
arg1Of |
IgG,respective |
R995 |
T1923 |
T1926 |
arg2Of |
disruption,demonstrated |
R9950 |
T14315 |
T14311 |
arg1Of |
IgG,peroxidase-conjugated |
R9951 |
T14315 |
T14312 |
arg1Of |
IgG,anti-rabbit |
R9952 |
T14315 |
T14314 |
arg1Of |
IgG,anti-mouse |
R9953 |
T14315 |
T14316 |
arg1Of |
IgG,( |
R9954 |
T14318 |
T14316 |
arg2Of |
dilutions,( |
R9955 |
T14318 |
T14317 |
arg1Of |
dilutions,1∶4000 |
R9956 |
T14318 |
T14319 |
arg1Of |
dilutions,; |
R9957 |
T14322 |
T14319 |
arg2Of |
Biotechnology,; |
R9958 |
T14322 |
T14320 |
arg1Of |
Biotechnology,Santa |
R9959 |
T14322 |
T14321 |
arg1Of |
Biotechnology,Cruz |
R996 |
T1923 |
T1928 |
arg1Of |
disruption,inhibit |
R9960 |
T14323 |
T14316 |
arg3Of |
),( |
R9961 |
T14325 |
T14324 |
arg1Of |
proteins,Immunoreactive |
R9962 |
T14325 |
T14326 |
arg1Of |
proteins,were |
R9963 |
T14325 |
T14327 |
arg2Of |
proteins,detected |
R9964 |
T14327 |
T14326 |
arg2Of |
detected,were |
R9965 |
T14327 |
T14328 |
arg1Of |
detected,with |
R9966 |
T14332 |
T14328 |
arg2Of |
system,with |
R9967 |
T14332 |
T14329 |
arg1Of |
system,the |
R9968 |
T14332 |
T14330 |
arg1Of |
system,ECL |
R9969 |
T14332 |
T14331 |
arg1Of |
system,detection |
R997 |
T1926 |
T1920 |
arg1Of |
demonstrated,Meanwhile |
R998 |
T1926 |
T1921 |
arg1Of |
demonstrated,"," |
R999 |
T1926 |
T1924 |
arg2Of |
demonstrated,has |