PMC:3317373 / 18096-19483 JSONTXT 24 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T7830 0-4 NN denotes Data
T7831 5-13 VB denotes obtained
T7832 14-18 IN denotes from
T7833 19-25 JJ denotes animal
T7834 26-33 NN denotes studies
T7835 34-41 VB denotes suggest
T7836 42-45 DT denotes the
T7837 46-57 NN denotes possibility
T7838 58-62 IN denotes that
T7839 63-74 JJ denotes antioxidant
T7840 75-81 NN denotes effect
T7841 82-84 IN denotes of
T7842 85-89 NN denotes Nrf2
T7843 90-93 MD denotes may
T7844 94-96 VB denotes be
T7845 97-105 VB denotes achieved
T7846 106-108 IN denotes by
T7847 109-120 NN denotes suppression
T7848 121-123 IN denotes of
T7849 124-139 JJ denotes proinflammatory
T7850 140-148 NN denotes pathways
T7851 149-154 WDT denotes which
T7852 155-158 VB denotes are
T7853 159-167 VB denotes mediated
T7854 168-170 IN denotes by
T7855 171-176 NN denotes NF-κB
T7856 177-186 NN denotes signaling
T7857 188-202 NN denotes Administration
T7858 203-205 IN denotes of
T7859 206-209 NN denotes SFN
T7860 210-212 VB denotes is
T7861 213-218 VB denotes found
T7862 219-221 TO denotes to
T7863 222-224 VB denotes be
T7864 225-229 JJ denotes able
T7865 230-232 TO denotes to
T7866 233-240 VB denotes inhibit
T7867 241-248 NN denotes IKK/IκB
T7868 249-264 NN denotes phosphorylation
T7869 265-268 CC denotes and
T7870 269-272 NN denotes p65
T7871 273-278 NN denotes NF-κB
T7872 279-286 NN denotes subunit
T7873 287-294 JJ denotes nuclear
T7874 295-308 NN denotes translocation
T7875 308-309 -COMMA- denotes ,
T7876 310-322 RB denotes consequently
T7877 323-334 VB denotes alleviating
T7878 335-340 NN denotes NF-κB
T7879 341-350 NN denotes signaling
T7880 351-352 -LRB- denotes [
T7881 352-354 CD denotes 21
T7882 354-355 -RRB- denotes ]
T7883 357-360 CC denotes And
T7884 361-366 NN denotes NF-κB
T7885 367-377 NN denotes activation
T7886 378-385 VB denotes induced
T7887 386-388 IN denotes by
T7888 389-407 NN denotes lipopolysaccharide
T7889 408-409 -LRB- denotes (
T7890 409-412 NN denotes LPS
T7891 412-413 -RRB- denotes )
T7892 414-419 MD denotes could
T7893 420-422 VB denotes be
T7894 423-433 VB denotes attenuated
T7895 434-436 IN denotes by
T7896 437-444 JJ denotes diverse
T7897 445-449 NN denotes Nrf2
T7898 450-460 NN denotes activators
T7899 460-461 -COMMA- denotes ,
T7900 462-466 JJ denotes such
T7901 467-469 IN denotes as
T7902 470-473 NN denotes SFN
T7903 474-477 CC denotes and
T7904 478-486 NN denotes curcumin
T7905 487-488 -LRB- denotes (
T7906 488-491 NN denotes CUR
T7907 491-492 -RRB- denotes )
T7908 493-494 -LRB- denotes [
T7909 494-496 CD denotes 22
T7910 496-497 -RRB- denotes ]
T7911 499-510 RB denotes Furthermore
T7912 510-511 -COMMA- denotes ,
T7913 512-515 PRP-DOLLAR- denotes our
T7914 516-524 JJ denotes previous
T7915 525-532 NN denotes studies
T7916 533-541 VB denotes indicate
T7917 542-546 IN denotes that
T7918 547-556 NN denotes depletion
T7919 557-559 IN denotes of
T7920 560-564 NN denotes Nrf2
T7921 565-572 VB denotes induces
T7922 573-585 NN denotes augmentation
T7923 586-588 IN denotes of
T7924 589-594 NN denotes NF-κB
T7925 595-603 NN denotes activity
T7926 604-607 CC denotes and
T7927 608-620 JJ denotes inflammatory
T7928 621-629 NN denotes response
T7929 630-632 IN denotes in
T7930 633-637 NN denotes lung
T7931 637-638 -COMMA- denotes ,
T7932 639-644 NN denotes brain
T7933 644-645 -COMMA- denotes ,
T7934 646-649 CC denotes and
T7935 650-659 NN denotes intestine
T7936 660-665 IN denotes after
T7937 666-669 NNP denotes TBI
T7938 670-671 -LRB- denotes [
T7939 671-672 CD denotes 4
T7940 672-673 -COMMA- denotes ,
T7941 674-675 CD denotes 5
T7942 675-676 -COMMA- denotes ,
T7943 677-679 CD denotes 23
T7944 679-680 -RRB- denotes ]
T7945 682-689 NN denotes Results
T7946 690-694 IN denotes from
T7947 695-699 DT denotes this
T7948 700-705 NN denotes study
T7949 706-713 RB denotes further
T7950 714-723 VB denotes confirmed
T7951 724-728 JJ denotes such
T7952 729-741 NN denotes relationship
T7953 742-749 VB denotes existed
T7954 750-752 IN denotes in
T7955 753-761 VB denotes cultured
T7956 762-772 NN denotes astrocytes
T7957 773-778 IN denotes after
T7958 779-786 NN denotes scratch
T7959 787-793 NN denotes injury
T7960 795-803 VB denotes Enhanced
T7961 804-814 NN denotes activation
T7962 815-817 IN denotes of
T7963 818-823 NN denotes NF-κB
T7964 824-826 VB denotes is
T7965 827-831 RB denotes also
T7966 832-842 VB denotes discovered
T7967 843-845 IN denotes in
T7968 846-850 NN denotes lung
T7969 850-851 -COMMA- denotes ,
T7970 852-863 NN denotes macrophages
T7971 863-864 -COMMA- denotes ,
T7972 865-868 CC denotes and
T7973 869-874 NN denotes mouse
T7974 875-884 JJ denotes embryonic
T7975 885-896 NN denotes fibroblasts
T7976 897-899 IN denotes of
T7977 900-914 JJ denotes Nrf2-deficient
T7978 915-919 NN denotes mice
T7979 920-925 IN denotes after
T7980 926-938 JJ denotes experimental
T7981 939-945 NN denotes sepsis
T7982 946-947 -LRB- denotes [
T7983 947-949 CD denotes 24
T7984 949-950 -RRB- denotes ]
T7985 952-965 RB denotes Interestingly
T7986 965-966 -COMMA- denotes ,
T7987 967-969 PRP denotes it
T7988 970-972 VB denotes is
T7989 973-981 VB denotes reported
T7990 982-986 IN denotes that
T7991 987-992 NN denotes NF-κB
T7992 993-996 MD denotes can
T7993 997-1004 VB denotes inhibit
T7994 1005-1009 NN denotes Nrf2
T7995 1010-1012 IN denotes at
T7996 1013-1028 JJ denotes transcriptional
T7997 1029-1034 NN denotes level
T7998 1036-1041 NN denotes NF-κB
T7999 1042-1045 NN denotes p65
T8000 1046-1053 NN denotes subunit
T8001 1054-1063 VB denotes repressed
T8002 1064-1067 DT denotes the
T8003 1068-1076 NN denotes Nrf2-ARE
T8004 1077-1084 NN denotes pathway
T8005 1085-1087 IN denotes at
T8006 1088-1103 JJ denotes transcriptional
T8007 1104-1109 NN denotes level
T8008 1110-1112 IN denotes by
T8009 1113-1124 JJ denotes competitive
T8010 1125-1136 NN denotes interaction
T8011 1137-1141 IN denotes with
T8012 1142-1145 DT denotes the
T8013 1146-1153 NN denotes CH1-KIX
T8014 1154-1160 NN denotes domain
T8015 1161-1163 IN denotes of
T8016 1164-1167 NN denotes CBP
T8017 1168-1170 CC denotes or
T8018 1171-1176 JJ denotes local
T8019 1177-1184 NN denotes histone
T8020 1185-1200 NN denotes hypoacetylation
T8021 1201-1202 -LRB- denotes [
T8022 1202-1204 CD denotes 25
T8023 1204-1205 -RRB- denotes ]
T8024 1207-1210 PDT denotes All
T8025 1211-1216 DT denotes these
T8026 1217-1225 NN denotes findings
T8027 1226-1234 VB denotes indicate
T8028 1235-1238 DT denotes the
T8029 1239-1248 JJ denotes potential
T8030 1249-1259 NN denotes complicate
T8031 1260-1269 NN denotes crosstalk
T8032 1270-1277 IN denotes between
T8033 1278-1283 NN denotes NF-κB
T8034 1284-1287 CC denotes and
T8035 1288-1292 NN denotes Nrf2
T8036 1292-1293 -COMMA- denotes ,
T8037 1294-1299 WDT denotes which
T8038 1300-1303 MD denotes may
T8039 1304-1306 VB denotes be
T8040 1307-1316 VB denotes regulated
T8041 1317-1319 IN denotes by
T8042 1320-1323 DT denotes the
T8043 1324-1332 JJ denotes upstream
T8044 1333-1350 JJ denotes mitogen-activated
T8045 1351-1358 NN denotes protein
T8046 1359-1365 NN denotes kinase
T8047 1366-1367 -LRB- denotes (
T8048 1367-1372 NN denotes MAPKs
T8049 1372-1373 -RRB- denotes )
T8050 1374-1381 NN denotes pathway
T8051 1382-1383 -LRB- denotes [
T8052 1383-1385 CD denotes 26
T8053 1385-1386 -RRB- denotes ]
R6373 T7830 T7831 arg2Of Data,obtained
R6374 T7830 T7835 arg1Of Data,suggest
R6375 T7831 T7832 arg1Of obtained,from
R6376 T7834 T7832 arg2Of studies,from
R6377 T7834 T7833 arg1Of studies,animal
R6378 T7837 T7835 arg2Of possibility,suggest
R6379 T7837 T7836 arg1Of possibility,the
R6380 T7840 T7839 arg1Of effect,antioxidant
R6381 T7840 T7841 arg1Of effect,of
R6382 T7840 T7843 arg1Of effect,may
R6383 T7840 T7844 arg1Of effect,be
R6384 T7840 T7845 arg2Of effect,achieved
R6385 T7842 T7841 arg2Of Nrf2,of
R6386 T7845 T7837 arg2Of achieved,possibility
R6387 T7845 T7838 arg1Of achieved,that
R6388 T7845 T7843 arg2Of achieved,may
R6389 T7845 T7844 arg2Of achieved,be
R6390 T7847 T7845 arg1Of suppression,achieved
R6391 T7847 T7846 arg2Of suppression,by
R6392 T7847 T7848 arg1Of suppression,of
R6393 T7850 T7848 arg2Of pathways,of
R6394 T7850 T7849 arg1Of pathways,proinflammatory
R6395 T7850 T7851 arg1Of pathways,which
R6396 T7850 T7852 arg1Of pathways,are
R6397 T7850 T7853 arg2Of pathways,mediated
R6398 T7853 T7852 arg2Of mediated,are
R6399 T7856 T7853 arg1Of signaling,mediated
R6400 T7856 T7854 arg2Of signaling,by
R6401 T7856 T7855 arg1Of signaling,NF-κB
R6402 T7857 T7858 arg1Of Administration,of
R6403 T7857 T7860 arg1Of Administration,is
R6404 T7857 T7861 arg2Of Administration,found
R6405 T7857 T7863 arg1Of Administration,be
R6406 T7857 T7864 arg1Of Administration,able
R6407 T7857 T7866 arg1Of Administration,inhibit
R6408 T7857 T7877 arg1Of Administration,alleviating
R6409 T7859 T7858 arg2Of SFN,of
R6410 T7861 T7860 arg2Of found,is
R6411 T7863 T7861 arg3Of be,found
R6412 T7863 T7862 arg1Of be,to
R6413 T7864 T7863 arg2Of able,be
R6414 T7866 T7864 arg2Of inhibit,able
R6415 T7866 T7865 arg1Of inhibit,to
R6416 T7866 T7875 arg1Of inhibit,","
R6417 T7866 T7877 modOf inhibit,alleviating
R6418 T7868 T7867 arg1Of phosphorylation,IKK/IκB
R6419 T7868 T7869 arg1Of phosphorylation,and
R6420 T7869 T7866 arg2Of and,inhibit
R6421 T7874 T7869 arg2Of translocation,and
R6422 T7874 T7870 arg1Of translocation,p65
R6423 T7874 T7871 arg1Of translocation,NF-κB
R6424 T7874 T7872 arg1Of translocation,subunit
R6425 T7874 T7873 arg1Of translocation,nuclear
R6426 T7877 T7876 arg1Of alleviating,consequently
R6427 T7879 T7877 arg2Of signaling,alleviating
R6428 T7879 T7878 arg1Of signaling,NF-κB
R6429 T7879 T7880 arg1Of signaling,[
R6430 T7881 T7880 arg2Of 21,[
R6431 T7882 T7880 arg3Of ],[
R6432 T7885 T7884 arg1Of activation,NF-κB
R6433 T7885 T7886 arg2Of activation,induced
R6434 T7885 T7892 arg1Of activation,could
R6435 T7885 T7893 arg1Of activation,be
R6436 T7885 T7894 arg2Of activation,attenuated
R6437 T7888 T7886 arg1Of lipopolysaccharide,induced
R6438 T7888 T7887 arg2Of lipopolysaccharide,by
R6439 T7888 T7889 arg1Of lipopolysaccharide,(
R6440 T7890 T7889 arg2Of LPS,(
R6441 T7891 T7889 arg3Of ),(
R6442 T7894 T7883 arg1Of attenuated,And
R6443 T7894 T7892 arg2Of attenuated,could
R6444 T7894 T7893 arg2Of attenuated,be
R6445 T7894 T7908 arg1Of attenuated,[
R6446 T7898 T7894 arg1Of activators,attenuated
R6447 T7898 T7895 arg2Of activators,by
R6448 T7898 T7896 arg1Of activators,diverse
R6449 T7898 T7897 arg1Of activators,Nrf2
R6450 T7898 T7899 arg1Of activators,","
R6451 T7898 T7901 arg1Of activators,as
R6452 T7901 T7900 arg1Of as,such
R6453 T7902 T7903 arg1Of SFN,and
R6454 T7903 T7901 arg2Of and,as
R6455 T7903 T7905 arg1Of and,(
R6456 T7904 T7903 arg2Of curcumin,and
R6457 T7906 T7905 arg2Of CUR,(
R6458 T7907 T7905 arg3Of ),(
R6459 T7909 T7908 arg2Of 22,[
R6460 T7910 T7908 arg3Of ],[
R6461 T7915 T7913 arg1Of studies,our
R6462 T7915 T7914 arg1Of studies,previous
R6463 T7915 T7916 arg1Of studies,indicate
R6464 T7916 T7911 arg1Of indicate,Furthermore
R6465 T7916 T7912 arg1Of indicate,","
R6466 T7918 T7919 arg1Of depletion,of
R6467 T7918 T7921 arg1Of depletion,induces
R6468 T7920 T7919 arg2Of Nrf2,of
R6469 T7921 T7916 arg2Of induces,indicate
R6470 T7921 T7917 arg1Of induces,that
R6471 T7922 T7921 arg2Of augmentation,induces
R6472 T7922 T7923 arg1Of augmentation,of
R6473 T7922 T7929 arg1Of augmentation,in
R6474 T7922 T7936 arg1Of augmentation,after
R6475 T7925 T7924 arg1Of activity,NF-κB
R6476 T7925 T7926 arg1Of activity,and
R6477 T7926 T7923 arg2Of and,of
R6478 T7928 T7926 arg2Of response,and
R6479 T7928 T7927 arg1Of response,inflammatory
R6480 T7930 T7931 arg1Of lung,","
R6481 T7931 T7934 arg1Of ",",and
R6482 T7932 T7931 arg2Of brain,","
R6483 T7934 T7929 arg2Of and,in
R6484 T7934 T7933 arg1Of and,","
R6485 T7935 T7934 arg2Of intestine,and
R6486 T7937 T7936 arg2Of TBI,after
R6487 T7937 T7938 arg1Of TBI,[
R6488 T7939 T7940 arg1Of 4,","
R6489 T7940 T7938 arg2Of ",",[
R6490 T7940 T7942 arg1Of ",",","
R6491 T7941 T7940 arg2Of 5,","
R6492 T7943 T7942 arg2Of 23,","
R6493 T7944 T7938 arg3Of ],[
R6494 T7945 T7946 arg1Of Results,from
R6495 T7945 T7950 arg1Of Results,confirmed
R6496 T7948 T7946 arg2Of study,from
R6497 T7948 T7947 arg1Of study,this
R6498 T7950 T7949 arg1Of confirmed,further
R6499 T7952 T7951 arg1Of relationship,such
R6500 T7952 T7953 arg1Of relationship,existed
R6501 T7953 T7950 arg2Of existed,confirmed
R6502 T7953 T7954 arg1Of existed,in
R6503 T7953 T7957 arg1Of existed,after
R6504 T7956 T7954 arg2Of astrocytes,in
R6505 T7956 T7955 arg2Of astrocytes,cultured
R6506 T7959 T7957 arg2Of injury,after
R6507 T7959 T7958 arg1Of injury,scratch
R6508 T7961 T7960 arg2Of activation,Enhanced
R6509 T7961 T7962 arg1Of activation,of
R6510 T7961 T7964 arg1Of activation,is
R6511 T7961 T7966 arg2Of activation,discovered
R6512 T7963 T7962 arg2Of NF-κB,of
R6513 T7966 T7964 arg2Of discovered,is
R6514 T7966 T7965 arg1Of discovered,also
R6515 T7966 T7967 arg1Of discovered,in
R6516 T7966 T7979 arg1Of discovered,after
R6517 T7966 T7982 arg1Of discovered,[
R6518 T7968 T7969 arg1Of lung,","
R6519 T7969 T7972 arg1Of ",",and
R6520 T7970 T7969 arg2Of macrophages,","
R6521 T7972 T7967 arg2Of and,in
R6522 T7972 T7971 arg1Of and,","
R6523 T7975 T7972 arg2Of fibroblasts,and
R6524 T7975 T7973 arg1Of fibroblasts,mouse
R6525 T7975 T7974 arg1Of fibroblasts,embryonic
R6526 T7975 T7976 arg1Of fibroblasts,of
R6527 T7978 T7976 arg2Of mice,of
R6528 T7978 T7977 arg1Of mice,Nrf2-deficient
R6529 T7981 T7979 arg2Of sepsis,after
R6530 T7981 T7980 arg1Of sepsis,experimental
R6531 T7983 T7982 arg2Of 24,[
R6532 T7984 T7982 arg3Of ],[
R6533 T7987 T7988 arg1Of it,is
R6534 T7987 T7989 arg2Of it,reported
R6535 T7989 T7985 arg1Of reported,Interestingly
R6536 T7989 T7986 arg1Of reported,","
R6537 T7989 T7988 arg2Of reported,is
R6538 T7991 T7992 arg1Of NF-κB,can
R6539 T7991 T7993 arg1Of NF-κB,inhibit
R6540 T7993 T7989 arg3Of inhibit,reported
R6541 T7993 T7990 arg1Of inhibit,that
R6542 T7993 T7992 arg2Of inhibit,can
R6543 T7993 T7995 arg1Of inhibit,at
R6544 T7994 T7993 arg2Of Nrf2,inhibit
R6545 T7997 T7995 arg2Of level,at
R6546 T7997 T7996 arg1Of level,transcriptional
R6547 T8000 T7998 arg1Of subunit,NF-κB
R6548 T8000 T7999 arg1Of subunit,p65
R6549 T8000 T8001 arg1Of subunit,repressed
R6550 T8001 T8008 arg1Of repressed,by
R6551 T8004 T8001 arg2Of pathway,repressed
R6552 T8004 T8002 arg1Of pathway,the
R6553 T8004 T8003 arg1Of pathway,Nrf2-ARE
R6554 T8004 T8005 arg1Of pathway,at
R6555 T8007 T8005 arg2Of level,at
R6556 T8007 T8006 arg1Of level,transcriptional
R6557 T8010 T8009 arg1Of interaction,competitive
R6558 T8010 T8011 arg1Of interaction,with
R6559 T8010 T8017 arg1Of interaction,or
R6560 T8014 T8011 arg2Of domain,with
R6561 T8014 T8012 arg1Of domain,the
R6562 T8014 T8013 arg1Of domain,CH1-KIX
R6563 T8014 T8015 arg1Of domain,of
R6564 T8016 T8015 arg2Of CBP,of
R6565 T8017 T8008 arg2Of or,by
R6566 T8020 T8017 arg2Of hypoacetylation,or
R6567 T8020 T8018 arg1Of hypoacetylation,local
R6568 T8020 T8019 arg1Of hypoacetylation,histone
R6569 T8020 T8021 arg1Of hypoacetylation,[
R6570 T8022 T8021 arg2Of 25,[
R6571 T8023 T8021 arg3Of ],[
R6572 T8026 T8024 arg1Of findings,All
R6573 T8026 T8025 arg1Of findings,these
R6574 T8026 T8027 arg1Of findings,indicate
R6575 T8031 T8027 arg2Of crosstalk,indicate
R6576 T8031 T8028 arg1Of crosstalk,the
R6577 T8031 T8029 arg1Of crosstalk,potential
R6578 T8031 T8030 arg1Of crosstalk,complicate
R6579 T8031 T8032 arg1Of crosstalk,between
R6580 T8033 T8034 arg1Of NF-κB,and
R6581 T8034 T8032 arg2Of and,between
R6582 T8034 T8036 arg1Of and,","
R6583 T8034 T8037 arg1Of and,which
R6584 T8034 T8038 arg1Of and,may
R6585 T8034 T8039 arg1Of and,be
R6586 T8034 T8040 arg2Of and,regulated
R6587 T8035 T8034 arg2Of Nrf2,and
R6588 T8040 T8038 arg2Of regulated,may
R6589 T8040 T8039 arg2Of regulated,be
R6590 T8040 T8051 arg1Of regulated,[
R6591 T8046 T8044 arg1Of kinase,mitogen-activated
R6592 T8046 T8045 arg1Of kinase,protein
R6593 T8046 T8047 arg1Of kinase,(
R6594 T8048 T8047 arg2Of MAPKs,(
R6595 T8049 T8047 arg3Of ),(
R6596 T8050 T8040 arg1Of pathway,regulated
R6597 T8050 T8041 arg2Of pathway,by
R6598 T8050 T8042 arg1Of pathway,the
R6599 T8050 T8043 arg1Of pathway,upstream
R6600 T8050 T8046 arg1Of pathway,kinase
R6601 T8052 T8051 arg2Of 26,[
R6602 T8053 T8051 arg3Of ],[