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PMC:3317373 / 15417-20739 JSONTXT 25 Projects

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Id Subject Object Predicate Lexical cue
T7368 14-17 DT denotes The
T7369 18-25 JJ denotes present
T7370 26-31 NN denotes study
T7371 32-44 VB denotes demonstrated
T7372 45-49 IN denotes that
T7373 50-57 NN denotes scratch
T7374 58-64 NN denotes injury
T7375 65-72 VB denotes induced
T7376 73-76 DT denotes the
T7377 77-89 NN denotes upregulation
T7378 90-92 IN denotes of
T7379 93-98 NN denotes NF-κB
T7380 99-102 NN denotes DNA
T7381 103-110 NN denotes binding
T7382 111-119 NN denotes activity
T7383 120-123 CC denotes and
T7384 124-138 NN denotes overexpression
T7385 139-141 IN denotes of
T7386 142-147 NN denotes TNF-α
T7387 147-148 -COMMA- denotes ,
T7388 149-154 NN denotes IL-1β
T7389 154-155 -COMMA- denotes ,
T7390 156-160 NN denotes IL-6
T7391 160-161 -COMMA- denotes ,
T7392 162-165 CC denotes and
T7393 166-170 NN denotes MMP9
T7394 171-173 IN denotes in
T7395 174-182 VB denotes cultured
T7396 183-193 NN denotes astrocytes
T7397 195-199 RB denotes Also
T7398 200-202 PRP denotes we
T7399 203-211 VB denotes revealed
T7400 212-216 IN denotes that
T7401 217-224 NN denotes scratch
T7402 225-231 NN denotes injury
T7403 232-239 VB denotes induced
T7404 240-246 JJ denotes higher
T7405 247-255 NN denotes activity
T7406 256-258 IN denotes of
T7407 259-264 NN denotes NF-κB
T7408 265-268 CC denotes and
T7409 269-277 VB denotes enhanced
T7410 278-288 NN denotes expression
T7411 289-291 IN denotes of
T7412 292-307 JJ denotes proinflammatory
T7413 308-317 NN denotes cytokines
T7414 318-320 IN denotes in
T7415 321-325 NN denotes Nrf2
T7416 326-334 NN denotes knockout
T7417 335-343 VB denotes cultured
T7418 344-354 NN denotes astrocytes
T7419 355-359 IN denotes than
T7420 360-365 DT denotes those
T7421 366-368 IN denotes in
T7422 369-377 JJ denotes wildtype
T7423 378-388 NN denotes astrocytes
T7424 389-392 IN denotes for
T7425 393-396 DT denotes the
T7426 397-402 JJ denotes first
T7427 403-407 NN denotes time
T7428 409-411 PRP denotes It
T7429 412-415 VB denotes has
T7430 416-420 VB denotes been
T7431 421-433 VB denotes demonstrated
T7432 434-438 IN denotes that
T7433 439-444 NN denotes NF-κB
T7434 445-447 VB denotes is
T7435 448-457 VB denotes activated
T7436 458-460 IN denotes in
T7437 461-466 NN denotes brain
T7438 467-470 CC denotes and
T7439 471-477 JJ denotes spinal
T7440 478-482 NN denotes cord
T7441 483-488 IN denotes after
T7442 489-498 JJ denotes traumatic
T7443 499-505 NN denotes injury
T7444 506-507 -LRB- denotes [
T7445 507-508 CD denotes 2
T7446 508-509 -COMMA- denotes ,
T7447 510-511 CD denotes 9
T7448 511-512 -RRB- denotes ]
T7449 514-516 IN denotes As
T7450 517-518 DT denotes a
T7451 519-529 NN denotes transcript
T7452 530-536 NN denotes factor
T7453 536-537 -COMMA- denotes ,
T7454 538-543 NN denotes NF-κB
T7455 544-549 VB denotes binds
T7456 550-554 IN denotes with
T7457 555-558 NN denotes DNA
T7458 559-563 IN denotes once
T7459 564-566 PRP denotes it
T7460 567-570 VB denotes was
T7461 571-580 VB denotes activated
T7462 581-584 CC denotes and
T7463 585-592 VB denotes induces
T7464 593-606 NN denotes transcription
T7465 607-609 IN denotes of
T7466 610-614 NN denotes MMP9
T7467 615-618 CC denotes and
T7468 619-620 DT denotes a
T7469 621-628 NN denotes battery
T7470 629-631 IN denotes of
T7471 632-647 JJ denotes proinflammatory
T7472 648-657 NN denotes cytokines
T7473 657-658 -COMMA- denotes ,
T7474 659-668 VB denotes including
T7475 669-674 NN denotes TNF-α
T7476 674-675 -COMMA- denotes ,
T7477 676-681 NN denotes IL-1β
T7478 681-682 -COMMA- denotes ,
T7479 683-686 CC denotes and
T7480 687-691 NN denotes IL-6
T7481 691-692 -COMMA- denotes ,
T7482 693-695 IN denotes in
T7483 696-701 NN denotes brain
T7484 702-709 NN denotes tissues
T7485 710-715 IN denotes after
T7486 716-719 NNP denotes TBI
T7487 720-721 -LRB- denotes [
T7488 721-722 CD denotes 3
T7489 722-723 -COMMA- denotes ,
T7490 724-726 CD denotes 10
T7491 726-727 -COMMA- denotes ,
T7492 728-730 CD denotes 11
T7493 730-731 -RRB- denotes ]
T7494 733-736 PRP-DOLLAR- denotes Our
T7495 737-744 NN denotes results
T7496 745-749 RB denotes also
T7497 750-758 VB denotes revealed
T7498 759-763 IN denotes that
T7499 764-771 NN denotes scratch
T7500 772-778 NN denotes injury
T7501 779-786 VB denotes induced
T7502 787-796 NN denotes elevation
T7503 797-799 IN denotes of
T7504 800-805 NN denotes NF-κB
T7505 806-809 NN denotes DNA
T7506 810-817 NN denotes binding
T7507 818-826 NN denotes activity
T7508 826-827 -COMMA- denotes ,
T7509 828-842 NN denotes overexpression
T7510 843-845 IN denotes of
T7511 846-850 NN denotes MMP9
T7512 850-851 -COMMA- denotes ,
T7513 852-855 CC denotes and
T7514 856-871 JJ denotes proinflammatory
T7515 872-881 NN denotes mediators
T7516 882-891 VB denotes mentioned
T7517 892-897 IN denotes above
T7518 898-900 IN denotes in
T7519 901-909 VB denotes cultured
T7520 910-920 NN denotes astrocytes
T7521 922-924 PRP denotes It
T7522 925-928 VB denotes has
T7523 929-933 VB denotes been
T7524 934-946 VB denotes demonstrated
T7525 947-951 IN denotes that
T7526 952-957 EX denotes there
T7527 958-960 VB denotes is
T7528 961-963 DT denotes an
T7529 964-978 JJ denotes autoregulatory
T7530 979-983 NN denotes loop
T7531 984-989 IN denotes among
T7532 990-995 DT denotes these
T7533 996-1011 JJ denotes proinflammatory
T7534 1012-1021 NN denotes mediators
T7535 1023-1026 IN denotes For
T7536 1027-1034 NN denotes example
T7537 1034-1035 -COMMA- denotes ,
T7538 1036-1041 NN denotes TNF-α
T7539 1042-1045 CC denotes and
T7540 1046-1051 NN denotes IL-1β
T7541 1052-1055 VB denotes are
T7542 1056-1062 JJ denotes potent
T7543 1063-1074 NN denotes stimulators
T7544 1075-1078 IN denotes for
T7545 1079-1083 NN denotes MMP9
T7546 1084-1086 IN denotes in
T7547 1087-1097 NN denotes astrocytes
T7548 1098-1099 -LRB- denotes [
T7549 1099-1101 CD denotes 12
T7550 1101-1102 -COMMA- denotes ,
T7551 1103-1105 CD denotes 13
T7552 1105-1106 -RRB- denotes ]
T7553 1106-1107 -COMMA- denotes ,
T7554 1108-1111 CC denotes and
T7555 1112-1116 NN denotes IL-6
T7556 1117-1124 VB denotes induces
T7557 1125-1139 NN denotes overexpression
T7558 1140-1142 IN denotes of
T7559 1143-1147 NN denotes MMP9
T7560 1148-1150 IN denotes in
T7561 1151-1156 JJ denotes human
T7562 1157-1162 NN denotes colon
T7563 1163-1172 NN denotes carcinoma
T7564 1173-1178 NN denotes cells
T7565 1179-1180 -LRB- denotes [
T7566 1180-1182 CD denotes 14
T7567 1182-1183 -RRB- denotes ]
T7568 1183-1184 -COMMA- denotes ,
T7569 1185-1188 CC denotes and
T7570 1189-1194 NN denotes TNF-α
T7571 1195-1198 CC denotes and
T7572 1199-1204 NN denotes IL-1β
T7573 1205-1209 RB denotes also
T7574 1210-1213 MD denotes can
T7575 1214-1220 VB denotes induce
T7576 1221-1231 NN denotes activation
T7577 1232-1234 IN denotes of
T7578 1235-1240 NN denotes NF-κB
T7579 1241-1242 -LRB- denotes [
T7580 1242-1244 CD denotes 15
T7581 1244-1245 -COMMA- denotes ,
T7582 1246-1248 CD denotes 16
T7583 1248-1249 -RRB- denotes ]
T7584 1251-1255 DT denotes This
T7585 1256-1270 JJ denotes autoregulatory
T7586 1271-1275 NN denotes loop
T7587 1276-1285 RB denotes extremely
T7588 1286-1296 VB denotes aggravates
T7589 1297-1300 DT denotes the
T7590 1301-1309 JJ denotes damaging
T7591 1310-1316 NN denotes effect
T7592 1317-1319 IN denotes of
T7593 1320-1332 NN denotes inflammation
T7594 1333-1336 CC denotes and
T7595 1337-1344 VB denotes induces
T7596 1345-1354 JJ denotes secondary
T7597 1355-1361 NN denotes injury
T7598 1362-1364 TO denotes to
T7599 1365-1370 NN denotes brain
T7600 1372-1374 PRP denotes It
T7601 1375-1377 VB denotes is
T7602 1378-1379 DT denotes a
T7603 1380-1384 JJ denotes good
T7604 1385-1391 NN denotes choice
T7605 1392-1395 IN denotes for
T7606 1396-1405 VB denotes targeting
T7607 1406-1408 IN denotes on
T7608 1409-1411 DT denotes an
T7609 1412-1420 JJ denotes upstream
T7610 1421-1427 NN denotes factor
T7611 1428-1430 TO denotes to
T7612 1431-1438 VB denotes prevent
T7613 1439-1443 JJ denotes such
T7614 1444-1458 JJ denotes autoregulatory
T7615 1459-1463 NN denotes loop
T7616 1464-1469 IN denotes after
T7617 1470-1473 NN denotes TBI
T7618 1475-1483 NN denotes Nrf2-ARE
T7619 1484-1491 NN denotes pathway
T7620 1492-1495 VB denotes has
T7621 1496-1500 VB denotes been
T7622 1501-1507 VB denotes proved
T7623 1508-1510 TO denotes to
T7624 1511-1513 VB denotes be
T7625 1514-1517 DT denotes the
T7626 1518-1521 JJ denotes key
T7627 1522-1531 NN denotes regulator
T7628 1532-1534 IN denotes in
T7629 1535-1543 VB denotes reducing
T7630 1544-1553 JJ denotes oxidative
T7631 1554-1560 NN denotes stress
T7632 1560-1561 -COMMA- denotes ,
T7633 1562-1574 JJ denotes inflammatory
T7634 1575-1581 NN denotes damage
T7635 1581-1582 -COMMA- denotes ,
T7636 1583-1586 CC denotes and
T7637 1587-1599 NN denotes accumulation
T7638 1600-1602 IN denotes of
T7639 1603-1608 JJ denotes toxic
T7640 1609-1620 NN denotes metabolites
T7641 1620-1621 -COMMA- denotes ,
T7642 1622-1627 WDT denotes which
T7643 1628-1631 VB denotes are
T7644 1632-1635 DT denotes all
T7645 1636-1644 VB denotes involved
T7646 1645-1647 IN denotes in
T7647 1648-1651 NNP denotes TBI
T7648 1653-1656 PRP-DOLLAR- denotes Our
T7649 1657-1665 JJ denotes previous
T7650 1666-1671 NN denotes study
T7651 1672-1675 VB denotes has
T7652 1676-1682 VB denotes proved
T7653 1683-1686 DT denotes the
T7654 1687-1699 NN denotes augmentation
T7655 1700-1702 IN denotes of
T7656 1703-1707 NN denotes Nrf2
T7657 1708-1710 IN denotes in
T7658 1711-1716 NN denotes brain
T7659 1717-1723 NN denotes tissue
T7660 1724-1729 IN denotes after
T7661 1730-1733 NNP denotes TBI
T7662 1734-1735 -LRB- denotes [
T7663 1735-1737 CD denotes 17
T7664 1737-1738 -RRB- denotes ]
T7665 1740-1748 VB denotes Enhanced
T7666 1749-1754 NN denotes level
T7667 1755-1757 IN denotes of
T7668 1758-1762 NN denotes Nrf2
T7669 1763-1772 VB denotes activates
T7670 1773-1786 NN denotes transcription
T7671 1787-1789 IN denotes of
T7672 1790-1791 DT denotes a
T7673 1792-1797 NN denotes group
T7674 1798-1800 IN denotes of
T7675 1801-1812 JJ denotes antioxidant
T7676 1813-1818 NN denotes genes
T7677 1818-1819 -COMMA- denotes ,
T7678 1820-1824 JJ denotes such
T7679 1825-1827 IN denotes as
T7680 1828-1832 NN denotes heme
T7681 1833-1844 NN denotes oxygenase-1
T7682 1845-1846 -LRB- denotes (
T7683 1846-1850 NN denotes HO-1
T7684 1850-1851 -RRB- denotes )
T7685 1852-1855 CC denotes and
T7686 1856-1859 NN denotes NAD
T7687 1860-1861 -LRB- denotes (
T7688 1861-1862 NN denotes P
T7689 1862-1863 -RRB- denotes )
T7690 1863-1864 NN denotes H
T7691 1864-1865 -COLON- denotes :
T7692 1866-1873 NN denotes quinone
T7693 1874-1890 NN denotes oxidoreductase-1
T7694 1891-1892 -LRB- denotes (
T7695 1892-1896 NN denotes NQO1
T7696 1896-1897 -RRB- denotes )
T7697 1897-1898 -COMMA- denotes ,
T7698 1899-1904 WDT denotes which
T7699 1905-1910 MD denotes would
T7700 1911-1923 RB denotes subsequently
T7701 1924-1930 VB denotes reduce
T7702 1931-1934 DT denotes the
T7703 1935-1941 NN denotes damage
T7704 1942-1944 IN denotes in
T7705 1945-1950 NN denotes brain
T7706 1951-1952 -LRB- denotes [
T7707 1952-1954 CD denotes 18
T7708 1954-1955 -RRB- denotes ]
T7709 1957-1967 NN denotes Postinjury
T7710 1968-1982 NN denotes administration
T7711 1983-1985 IN denotes of
T7712 1986-1989 NNP denotes SFN
T7713 1989-1990 -COMMA- denotes ,
T7714 1991-1993 DT denotes an
T7715 1994-2001 NN denotes inducer
T7716 2002-2004 IN denotes of
T7717 2005-2009 NN denotes Nrf2
T7718 2009-2010 -COMMA- denotes ,
T7719 2011-2024 RB denotes significantly
T7720 2025-2033 VB denotes improves
T7721 2034-2041 JJ denotes spatial
T7722 2042-2048 NN denotes memory
T7723 2049-2051 IN denotes of
T7724 2052-2055 NN denotes rat
T7725 2056-2059 CC denotes and
T7726 2060-2069 VB denotes decreases
T7727 2070-2073 DT denotes the
T7728 2074-2090 NN denotes immunoreactivity
T7729 2091-2094 IN denotes for
T7730 2095-2111 JJ denotes 4-Hydroxynonenal
T7731 2112-2113 -LRB- denotes (
T7732 2113-2118 NN denotes 4-HNE
T7733 2118-2119 -RRB- denotes )
T7734 2119-2120 -COMMA- denotes ,
T7735 2121-2122 DT denotes a
T7736 2123-2129 NN denotes marker
T7737 2130-2132 IN denotes of
T7738 2133-2138 NN denotes lipid
T7739 2139-2151 NN denotes peroxidation
T7740 2151-2152 -COMMA- denotes ,
T7741 2153-2155 IN denotes in
T7742 2156-2159 DT denotes the
T7743 2160-2166 NN denotes cortex
T7744 2167-2170 CC denotes and
T7745 2171-2174 DT denotes the
T7746 2175-2178 NN denotes CA3
T7747 2179-2187 NN denotes subfield
T7748 2188-2190 IN denotes of
T7749 2191-2202 NN denotes hippocampus
T7750 2203-2208 IN denotes after
T7751 2209-2212 NNP denotes TBI
T7752 2213-2214 -LRB- denotes [
T7753 2214-2216 CD denotes 19
T7754 2216-2217 -RRB- denotes ]
T7755 2219-2221 IN denotes On
T7756 2222-2225 DT denotes the
T7757 2226-2231 JJ denotes other
T7758 2232-2236 NN denotes hand
T7759 2236-2237 -COMMA- denotes ,
T7760 2238-2252 JJ denotes Nrf2-deficient
T7761 2253-2257 NN denotes mice
T7762 2258-2264 VB denotes appear
T7763 2265-2269 RB denotes more
T7764 2270-2281 JJ denotes susceptible
T7765 2282-2284 TO denotes to
T7766 2285-2288 NNP denotes TBI
T7767 2290-2299 NN denotes Depletion
T7768 2300-2302 IN denotes of
T7769 2303-2307 NN denotes Nrf2
T7770 2308-2315 VB denotes induces
T7771 2316-2322 JJ denotes higher
T7772 2323-2333 NN denotes expression
T7773 2334-2336 IN denotes of
T7774 2337-2352 JJ denotes proinflammatory
T7775 2353-2362 NN denotes mediators
T7776 2363-2365 IN denotes in
T7777 2366-2371 NN denotes brain
T7778 2372-2377 IN denotes after
T7779 2378-2381 NNP denotes TBI
T7780 2382-2383 -LRB- denotes [
T7781 2383-2385 CD denotes 20
T7782 2385-2386 -RRB- denotes ]
T7783 2388-2392 RB denotes Here
T7784 2392-2393 -COMMA- denotes ,
T7785 2394-2397 PRP-DOLLAR- denotes our
T7786 2398-2405 NN denotes results
T7787 2406-2414 VB denotes revealed
T7788 2415-2419 IN denotes that
T7789 2420-2434 NN denotes overexpression
T7790 2435-2437 IN denotes of
T7791 2438-2443 NN denotes TNF-α
T7792 2443-2444 -COMMA- denotes ,
T7793 2445-2450 NN denotes IL-1β
T7794 2450-2451 -COMMA- denotes ,
T7795 2452-2456 NN denotes IL-6
T7796 2456-2457 -COMMA- denotes ,
T7797 2458-2461 CC denotes and
T7798 2462-2466 NN denotes MMP9
T7799 2467-2472 IN denotes after
T7800 2473-2480 NN denotes scratch
T7801 2481-2487 NN denotes injury
T7802 2488-2491 VB denotes was
T7803 2492-2496 RB denotes more
T7804 2497-2507 VB denotes aggravated
T7805 2508-2510 IN denotes in
T7806 2511-2519 VB denotes cultured
T7807 2520-2524 NN denotes Nrf2
T7808 2525-2533 NN denotes knockout
T7809 2534-2544 NN denotes astrocytes
T7810 2545-2549 IN denotes than
T7811 2550-2552 IN denotes in
T7812 2553-2561 JJ denotes wildtype
T7813 2562-2573 NN denotes astrocyetes
T7814 2574-2577 IN denotes for
T7815 2578-2581 DT denotes the
T7816 2582-2587 JJ denotes first
T7817 2588-2592 NN denotes time
T7818 2592-2593 -COMMA- denotes ,
T7819 2594-2597 CC denotes and
T7820 2598-2612 NN denotes overexpression
T7821 2613-2615 IN denotes of
T7822 2616-2621 DT denotes these
T7823 2622-2637 JJ denotes proinflammatory
T7824 2638-2647 NN denotes mediators
T7825 2648-2651 VB denotes led
T7826 2652-2654 TO denotes to
T7827 2655-2659 JJ denotes more
T7828 2660-2670 NN denotes astrocytes
T7829 2671-2677 NN denotes deaths
T7830 2679-2683 NN denotes Data
T7831 2684-2692 VB denotes obtained
T7832 2693-2697 IN denotes from
T7833 2698-2704 JJ denotes animal
T7834 2705-2712 NN denotes studies
T7835 2713-2720 VB denotes suggest
T7836 2721-2724 DT denotes the
T7837 2725-2736 NN denotes possibility
T7838 2737-2741 IN denotes that
T7839 2742-2753 JJ denotes antioxidant
T7840 2754-2760 NN denotes effect
T7841 2761-2763 IN denotes of
T7842 2764-2768 NN denotes Nrf2
T7843 2769-2772 MD denotes may
T7844 2773-2775 VB denotes be
T7845 2776-2784 VB denotes achieved
T7846 2785-2787 IN denotes by
T7847 2788-2799 NN denotes suppression
T7848 2800-2802 IN denotes of
T7849 2803-2818 JJ denotes proinflammatory
T7850 2819-2827 NN denotes pathways
T7851 2828-2833 WDT denotes which
T7852 2834-2837 VB denotes are
T7853 2838-2846 VB denotes mediated
T7854 2847-2849 IN denotes by
T7855 2850-2855 NN denotes NF-κB
T7856 2856-2865 NN denotes signaling
T7857 2867-2881 NN denotes Administration
T7858 2882-2884 IN denotes of
T7859 2885-2888 NN denotes SFN
T7860 2889-2891 VB denotes is
T7861 2892-2897 VB denotes found
T7862 2898-2900 TO denotes to
T7863 2901-2903 VB denotes be
T7864 2904-2908 JJ denotes able
T7865 2909-2911 TO denotes to
T7866 2912-2919 VB denotes inhibit
T7867 2920-2927 NN denotes IKK/IκB
T7868 2928-2943 NN denotes phosphorylation
T7869 2944-2947 CC denotes and
T7870 2948-2951 NN denotes p65
T7871 2952-2957 NN denotes NF-κB
T7872 2958-2965 NN denotes subunit
T7873 2966-2973 JJ denotes nuclear
T7874 2974-2987 NN denotes translocation
T7875 2987-2988 -COMMA- denotes ,
T7876 2989-3001 RB denotes consequently
T7877 3002-3013 VB denotes alleviating
T7878 3014-3019 NN denotes NF-κB
T7879 3020-3029 NN denotes signaling
T7880 3030-3031 -LRB- denotes [
T7881 3031-3033 CD denotes 21
T7882 3033-3034 -RRB- denotes ]
T7883 3036-3039 CC denotes And
T7884 3040-3045 NN denotes NF-κB
T7885 3046-3056 NN denotes activation
T7886 3057-3064 VB denotes induced
T7887 3065-3067 IN denotes by
T7888 3068-3086 NN denotes lipopolysaccharide
T7889 3087-3088 -LRB- denotes (
T7890 3088-3091 NN denotes LPS
T7891 3091-3092 -RRB- denotes )
T7892 3093-3098 MD denotes could
T7893 3099-3101 VB denotes be
T7894 3102-3112 VB denotes attenuated
T7895 3113-3115 IN denotes by
T7896 3116-3123 JJ denotes diverse
T7897 3124-3128 NN denotes Nrf2
T7898 3129-3139 NN denotes activators
T7899 3139-3140 -COMMA- denotes ,
T7900 3141-3145 JJ denotes such
T7901 3146-3148 IN denotes as
T7902 3149-3152 NN denotes SFN
T7903 3153-3156 CC denotes and
T7904 3157-3165 NN denotes curcumin
T7905 3166-3167 -LRB- denotes (
T7906 3167-3170 NN denotes CUR
T7907 3170-3171 -RRB- denotes )
T7908 3172-3173 -LRB- denotes [
T7909 3173-3175 CD denotes 22
T7910 3175-3176 -RRB- denotes ]
T7911 3178-3189 RB denotes Furthermore
T7912 3189-3190 -COMMA- denotes ,
T7913 3191-3194 PRP-DOLLAR- denotes our
T7914 3195-3203 JJ denotes previous
T7915 3204-3211 NN denotes studies
T7916 3212-3220 VB denotes indicate
T7917 3221-3225 IN denotes that
T7918 3226-3235 NN denotes depletion
T7919 3236-3238 IN denotes of
T7920 3239-3243 NN denotes Nrf2
T7921 3244-3251 VB denotes induces
T7922 3252-3264 NN denotes augmentation
T7923 3265-3267 IN denotes of
T7924 3268-3273 NN denotes NF-κB
T7925 3274-3282 NN denotes activity
T7926 3283-3286 CC denotes and
T7927 3287-3299 JJ denotes inflammatory
T7928 3300-3308 NN denotes response
T7929 3309-3311 IN denotes in
T7930 3312-3316 NN denotes lung
T7931 3316-3317 -COMMA- denotes ,
T7932 3318-3323 NN denotes brain
T7933 3323-3324 -COMMA- denotes ,
T7934 3325-3328 CC denotes and
T7935 3329-3338 NN denotes intestine
T7936 3339-3344 IN denotes after
T7937 3345-3348 NNP denotes TBI
T7938 3349-3350 -LRB- denotes [
T7939 3350-3351 CD denotes 4
T7940 3351-3352 -COMMA- denotes ,
T7941 3353-3354 CD denotes 5
T7942 3354-3355 -COMMA- denotes ,
T7943 3356-3358 CD denotes 23
T7944 3358-3359 -RRB- denotes ]
T7945 3361-3368 NN denotes Results
T7946 3369-3373 IN denotes from
T7947 3374-3378 DT denotes this
T7948 3379-3384 NN denotes study
T7949 3385-3392 RB denotes further
T7950 3393-3402 VB denotes confirmed
T7951 3403-3407 JJ denotes such
T7952 3408-3420 NN denotes relationship
T7953 3421-3428 VB denotes existed
T7954 3429-3431 IN denotes in
T7955 3432-3440 VB denotes cultured
T7956 3441-3451 NN denotes astrocytes
T7957 3452-3457 IN denotes after
T7958 3458-3465 NN denotes scratch
T7959 3466-3472 NN denotes injury
T7960 3474-3482 VB denotes Enhanced
T7961 3483-3493 NN denotes activation
T7962 3494-3496 IN denotes of
T7963 3497-3502 NN denotes NF-κB
T7964 3503-3505 VB denotes is
T7965 3506-3510 RB denotes also
T7966 3511-3521 VB denotes discovered
T7967 3522-3524 IN denotes in
T7968 3525-3529 NN denotes lung
T7969 3529-3530 -COMMA- denotes ,
T7970 3531-3542 NN denotes macrophages
T7971 3542-3543 -COMMA- denotes ,
T7972 3544-3547 CC denotes and
T7973 3548-3553 NN denotes mouse
T7974 3554-3563 JJ denotes embryonic
T7975 3564-3575 NN denotes fibroblasts
T7976 3576-3578 IN denotes of
T7977 3579-3593 JJ denotes Nrf2-deficient
T7978 3594-3598 NN denotes mice
T7979 3599-3604 IN denotes after
T7980 3605-3617 JJ denotes experimental
T7981 3618-3624 NN denotes sepsis
T7982 3625-3626 -LRB- denotes [
T7983 3626-3628 CD denotes 24
T7984 3628-3629 -RRB- denotes ]
T7985 3631-3644 RB denotes Interestingly
T7986 3644-3645 -COMMA- denotes ,
T7987 3646-3648 PRP denotes it
T7988 3649-3651 VB denotes is
T7989 3652-3660 VB denotes reported
T7990 3661-3665 IN denotes that
T7991 3666-3671 NN denotes NF-κB
T7992 3672-3675 MD denotes can
T7993 3676-3683 VB denotes inhibit
T7994 3684-3688 NN denotes Nrf2
T7995 3689-3691 IN denotes at
T7996 3692-3707 JJ denotes transcriptional
T7997 3708-3713 NN denotes level
T7998 3715-3720 NN denotes NF-κB
T7999 3721-3724 NN denotes p65
T8000 3725-3732 NN denotes subunit
T8001 3733-3742 VB denotes repressed
T8002 3743-3746 DT denotes the
T8003 3747-3755 NN denotes Nrf2-ARE
T8004 3756-3763 NN denotes pathway
T8005 3764-3766 IN denotes at
T8006 3767-3782 JJ denotes transcriptional
T8007 3783-3788 NN denotes level
T8008 3789-3791 IN denotes by
T8009 3792-3803 JJ denotes competitive
T8010 3804-3815 NN denotes interaction
T8011 3816-3820 IN denotes with
T8012 3821-3824 DT denotes the
T8013 3825-3832 NN denotes CH1-KIX
T8014 3833-3839 NN denotes domain
T8015 3840-3842 IN denotes of
T8016 3843-3846 NN denotes CBP
T8017 3847-3849 CC denotes or
T8018 3850-3855 JJ denotes local
T8019 3856-3863 NN denotes histone
T8020 3864-3879 NN denotes hypoacetylation
T8021 3880-3881 -LRB- denotes [
T8022 3881-3883 CD denotes 25
T8023 3883-3884 -RRB- denotes ]
T8024 3886-3889 PDT denotes All
T8025 3890-3895 DT denotes these
T8026 3896-3904 NN denotes findings
T8027 3905-3913 VB denotes indicate
T8028 3914-3917 DT denotes the
T8029 3918-3927 JJ denotes potential
T8030 3928-3938 NN denotes complicate
T8031 3939-3948 NN denotes crosstalk
T8032 3949-3956 IN denotes between
T8033 3957-3962 NN denotes NF-κB
T8034 3963-3966 CC denotes and
T8035 3967-3971 NN denotes Nrf2
T8036 3971-3972 -COMMA- denotes ,
T8037 3973-3978 WDT denotes which
T8038 3979-3982 MD denotes may
T8039 3983-3985 VB denotes be
T8040 3986-3995 VB denotes regulated
T8041 3996-3998 IN denotes by
T8042 3999-4002 DT denotes the
T8043 4003-4011 JJ denotes upstream
T8044 4012-4029 JJ denotes mitogen-activated
T8045 4030-4037 NN denotes protein
T8046 4038-4044 NN denotes kinase
T8047 4045-4046 -LRB- denotes (
T8048 4046-4051 NN denotes MAPKs
T8049 4051-4052 -RRB- denotes )
T8050 4053-4060 NN denotes pathway
T8051 4061-4062 -LRB- denotes [
T8052 4062-4064 CD denotes 26
T8053 4064-4065 -RRB- denotes ]
T8054 4067-4069 PRP denotes It
T8055 4070-4073 VB denotes has
T8056 4074-4078 VB denotes been
T8057 4079-4088 VB denotes confirmed
T8058 4089-4093 IN denotes that
T8059 4094-4098 NN denotes Nrf2
T8060 4099-4101 VB denotes is
T8061 4102-4108 RB denotes mainly
T8062 4109-4117 VB denotes detected
T8063 4118-4120 IN denotes in
T8064 4121-4128 NN denotes nucleus
T8065 4129-4131 IN denotes of
T8066 4132-4142 NN denotes astrocytes
T8067 4143-4148 IN denotes after
T8068 4149-4152 NNP denotes TBI
T8069 4153-4154 -LRB- denotes [
T8070 4154-4156 CD denotes 18
T8071 4156-4157 -RRB- denotes ]
T8072 4159-4161 IN denotes In
T8073 4162-4166 NN denotes view
T8074 4167-4169 IN denotes of
T8075 4170-4173 DT denotes the
T8076 4174-4178 NN denotes fact
T8077 4179-4183 IN denotes that
T8078 4184-4188 NN denotes Nrf2
T8079 4189-4191 VB denotes is
T8080 4192-4193 DT denotes a
T8081 4194-4207 NN denotes transcription
T8082 4208-4214 NN denotes factor
T8083 4215-4220 WDT denotes which
T8084 4221-4227 MD denotes should
T8085 4228-4232 VB denotes take
T8086 4233-4241 NN denotes function
T8087 4242-4248 RB denotes mainly
T8088 4249-4251 IN denotes in
T8089 4252-4259 NN denotes nucleus
T8090 4259-4260 -COMMA- denotes ,
T8091 4261-4263 PRP denotes it
T8092 4264-4267 MD denotes can
T8093 4268-4270 VB denotes be
T8094 4271-4279 VB denotes reasoned
T8095 4280-4284 IN denotes that
T8096 4285-4295 NN denotes astrocytes
T8097 4296-4299 MD denotes may
T8098 4300-4302 VB denotes be
T8099 4303-4306 CD denotes one
T8100 4307-4311 NN denotes kind
T8101 4312-4314 IN denotes of
T8102 4315-4325 NN denotes respondent
T8103 4326-4331 NN denotes cells
T8104 4332-4334 IN denotes in
T8105 4335-4345 NN denotes activation
T8106 4346-4348 IN denotes of
T8107 4349-4357 NN denotes Nrf2-ARE
T8108 4358-4365 NN denotes pathway
T8109 4366-4371 IN denotes after
T8110 4372-4375 NN denotes TBI
T8111 4377-4385 JJ denotes Previous
T8112 4386-4391 NN denotes study
T8113 4392-4402 VB denotes identified
T8114 4403-4406 DT denotes the
T8115 4407-4417 NN denotes expression
T8116 4418-4420 IN denotes of
T8117 4421-4426 NN denotes TNF-α
T8118 4426-4427 -COMMA- denotes ,
T8119 4428-4433 NN denotes IL-1β
T8120 4433-4434 -COMMA- denotes ,
T8121 4435-4438 CC denotes and
T8122 4439-4443 NN denotes IL-6
T8123 4444-4446 IN denotes in
T8124 4447-4455 VB denotes cultured
T8125 4456-4466 NN denotes astrocytes
T8126 4467-4472 IN denotes after
T8127 4473-4482 NN denotes treatment
T8128 4483-4487 IN denotes with
T8129 4488-4491 NN denotes LPS
T8130 4492-4494 CC denotes or
T8131 4495-4508 NN denotes oxyhemoglobin
T8132 4509-4510 -LRB- denotes [
T8133 4510-4512 CD denotes 27
T8134 4512-4513 -COMMA- denotes ,
T8135 4514-4516 CD denotes 28
T8136 4516-4517 -RRB- denotes ]
T8137 4519-4526 DT denotes Another
T8138 4527-4532 NN denotes study
T8139 4533-4541 VB denotes revealed
T8140 4542-4546 IN denotes that
T8141 4547-4552 IN denotes after
T8142 4553-4559 JJ denotes middle
T8143 4560-4568 JJ denotes cerebral
T8144 4569-4575 NN denotes artery
T8145 4576-4585 NN denotes occlusion
T8146 4585-4586 -COMMA- denotes ,
T8147 4587-4600 JJ denotes MMP9-positive
T8148 4601-4611 NN denotes astrocytes
T8149 4612-4616 VB denotes were
T8150 4617-4625 VB denotes observed
T8151 4626-4628 IN denotes in
T8152 4629-4634 NN denotes brain
T8153 4635-4642 NN denotes tissues
T8154 4643-4645 IN denotes by
T8155 4646-4666 NN denotes immunohistochemistry
T8156 4667-4668 -LRB- denotes [
T8157 4668-4670 CD denotes 29
T8158 4670-4671 -RRB- denotes ]
T8159 4673-4678 DT denotes Those
T8160 4679-4686 NN denotes results
T8161 4687-4695 VB denotes indicate
T8162 4696-4699 DT denotes the
T8163 4700-4704 NN denotes role
T8164 4705-4707 IN denotes of
T8165 4708-4718 NN denotes astrocytes
T8166 4719-4721 IN denotes in
T8167 4722-4734 JJ denotes inflammatory
T8168 4735-4742 NN denotes process
T8169 4743-4748 IN denotes after
T8170 4749-4754 NN denotes brain
T8171 4755-4761 NN denotes injury
T8172 4763-4766 CC denotes But
T8173 4767-4771 RB denotes till
T8174 4772-4775 RB denotes now
T8175 4775-4776 -COMMA- denotes ,
T8176 4777-4782 EX denotes there
T8177 4783-4785 VB denotes is
T8178 4786-4788 DT denotes no
T8179 4789-4794 NN denotes study
T8180 4795-4802 VB denotes focused
T8181 4803-4805 IN denotes on
T8182 4806-4809 DT denotes the
T8183 4810-4822 NN denotes relationship
T8184 4823-4828 IN denotes among
T8185 4829-4839 NN denotes astrocytes
T8186 4839-4840 -COMMA- denotes ,
T8187 4841-4845 NN denotes Nrf2
T8188 4845-4846 -COMMA- denotes ,
T8189 4847-4850 CC denotes and
T8190 4851-4866 JJ denotes proinflammatory
T8191 4867-4876 NN denotes mediators
T8192 4877-4882 IN denotes after
T8193 4883-4886 NN denotes TBI
T8194 4888-4891 PRP-DOLLAR- denotes Our
T8195 4892-4899 NN denotes results
T8196 4900-4912 VB denotes demonstrated
T8197 4913-4916 DT denotes the
T8198 4917-4928 VB denotes upregulated
T8199 4929-4939 NN denotes expression
T8200 4940-4942 IN denotes of
T8201 4943-4948 NN denotes TNF-α
T8202 4948-4949 -COMMA- denotes ,
T8203 4950-4955 NN denotes IL-1β
T8204 4955-4956 -COMMA- denotes ,
T8205 4957-4961 NN denotes IL-6
T8206 4961-4962 -COMMA- denotes ,
T8207 4963-4966 CC denotes and
T8208 4967-4971 NN denotes MMP9
T8209 4972-4974 IN denotes in
T8210 4975-4979 NN denotes Nrf2
T8211 4980-4988 NN denotes knockout
T8212 4989-4999 NN denotes astrocytes
T8213 5000-5005 IN denotes after
T8214 5006-5013 NN denotes scratch
T8215 5014-5020 NN denotes injury
T8216 5021-5024 IN denotes for
T8217 5025-5028 DT denotes the
T8218 5029-5034 JJ denotes first
T8219 5035-5039 NN denotes time
T8220 5041-5043 IN denotes In
T8221 5044-5054 NN denotes conclusion
T8222 5054-5055 -COMMA- denotes ,
T8223 5056-5065 NN denotes depletion
T8224 5066-5068 IN denotes of
T8225 5069-5073 NN denotes Nrf2
T8226 5074-5081 VB denotes induced
T8227 5082-5085 DT denotes the
T8228 5086-5096 NN denotes activation
T8229 5097-5099 IN denotes of
T8230 5100-5105 NN denotes NF-κB
T8231 5106-5109 CC denotes and
T8232 5110-5113 DT denotes the
T8233 5114-5124 NN denotes expression
T8234 5125-5127 IN denotes of
T8235 5128-5133 NN denotes TNF-α
T8236 5133-5134 -COMMA- denotes ,
T8237 5135-5140 NN denotes IL-1β
T8238 5140-5141 -COMMA- denotes ,
T8239 5142-5146 NN denotes IL-6
T8240 5146-5147 -COMMA- denotes ,
T8241 5148-5151 CC denotes and
T8242 5152-5156 NN denotes MMP9
T8243 5157-5166 VB denotes resulting
T8244 5167-5169 IN denotes in
T8245 5170-5174 JJ denotes more
T8246 5175-5179 NN denotes cell
T8247 5180-5186 NN denotes deaths
T8248 5187-5189 IN denotes in
T8249 5190-5200 NN denotes astrocytes
T8250 5201-5206 IN denotes after
T8251 5207-5214 NN denotes scratch
T8252 5215-5221 NN denotes injury
T8253 5223-5228 DT denotes These
T8254 5229-5236 NN denotes results
T8255 5237-5244 VB denotes suggest
T8256 5245-5249 IN denotes that
T8257 5250-5254 NN denotes Nrf2
T8258 5255-5258 MD denotes may
T8259 5259-5261 VB denotes be
T8260 5262-5264 DT denotes an
T8261 5265-5274 JJ denotes important
T8262 5275-5281 NN denotes target
T8263 5282-5285 IN denotes for
T8264 5286-5303 JJ denotes anti-inflammatory
T8265 5304-5311 NN denotes therapy
T8266 5312-5317 IN denotes after
T8267 5318-5321 NN denotes TBI
R5909 T7370 T7368 arg1Of study,The
R5910 T7370 T7369 arg1Of study,present
R5911 T7370 T7371 arg1Of study,demonstrated
R5912 T7374 T7373 arg1Of injury,scratch
R5913 T7374 T7375 arg1Of injury,induced
R5914 T7375 T7371 arg2Of induced,demonstrated
R5915 T7375 T7372 arg1Of induced,that
R5916 T7377 T7376 arg1Of upregulation,the
R5917 T7377 T7378 arg1Of upregulation,of
R5918 T7377 T7383 arg1Of upregulation,and
R5919 T7382 T7378 arg2Of activity,of
R5920 T7382 T7379 arg1Of activity,NF-κB
R5921 T7382 T7380 arg1Of activity,DNA
R5922 T7382 T7381 arg1Of activity,binding
R5923 T7383 T7375 arg2Of and,induced
R5924 T7384 T7383 arg2Of overexpression,and
R5925 T7384 T7385 arg1Of overexpression,of
R5926 T7386 T7387 arg1Of TNF-α,","
R5927 T7387 T7389 arg1Of ",",","
R5928 T7388 T7387 arg2Of IL-1β,","
R5929 T7389 T7392 arg1Of ",",and
R5930 T7390 T7389 arg2Of IL-6,","
R5931 T7392 T7385 arg2Of and,of
R5932 T7392 T7391 arg1Of and,","
R5933 T7392 T7394 arg1Of and,in
R5934 T7393 T7392 arg2Of MMP9,and
R5935 T7396 T7394 arg2Of astrocytes,in
R5936 T7396 T7395 arg2Of astrocytes,cultured
R5937 T7398 T7399 arg1Of we,revealed
R5938 T7399 T7397 arg1Of revealed,Also
R5939 T7402 T7401 arg1Of injury,scratch
R5940 T7402 T7403 arg1Of injury,induced
R5941 T7403 T7399 arg2Of induced,revealed
R5942 T7403 T7400 arg1Of induced,that
R5943 T7405 T7404 arg1Of activity,higher
R5944 T7405 T7406 arg1Of activity,of
R5945 T7405 T7408 arg1Of activity,and
R5946 T7407 T7406 arg2Of NF-κB,of
R5947 T7408 T7403 arg2Of and,induced
R5948 T7410 T7408 arg2Of expression,and
R5949 T7410 T7409 arg2Of expression,enhanced
R5950 T7410 T7411 arg1Of expression,of
R5951 T7410 T7414 arg1Of expression,in
R5952 T7413 T7411 arg2Of cytokines,of
R5953 T7413 T7412 arg1Of cytokines,proinflammatory
R5954 T7418 T7414 arg2Of astrocytes,in
R5955 T7418 T7415 arg1Of astrocytes,Nrf2
R5956 T7418 T7416 arg1Of astrocytes,knockout
R5957 T7418 T7417 arg2Of astrocytes,cultured
R5958 T7418 T7419 arg1Of astrocytes,than
R5959 T7420 T7419 arg2Of those,than
R5960 T7420 T7421 arg1Of those,in
R5961 T7423 T7421 arg2Of astrocytes,in
R5962 T7423 T7422 arg1Of astrocytes,wildtype
R5963 T7423 T7424 arg1Of astrocytes,for
R5964 T7427 T7424 arg2Of time,for
R5965 T7427 T7425 arg1Of time,the
R5966 T7427 T7426 arg1Of time,first
R5967 T7428 T7429 arg1Of It,has
R5968 T7428 T7430 arg1Of It,been
R5969 T7428 T7431 arg2Of It,demonstrated
R5970 T7431 T7429 arg2Of demonstrated,has
R5971 T7431 T7430 arg2Of demonstrated,been
R5972 T7433 T7434 arg1Of NF-κB,is
R5973 T7433 T7435 arg2Of NF-κB,activated
R5974 T7435 T7431 arg3Of activated,demonstrated
R5975 T7435 T7432 arg1Of activated,that
R5976 T7435 T7434 arg2Of activated,is
R5977 T7435 T7436 arg1Of activated,in
R5978 T7435 T7441 arg1Of activated,after
R5979 T7435 T7444 arg1Of activated,[
R5980 T7437 T7438 arg1Of brain,and
R5981 T7438 T7436 arg2Of and,in
R5982 T7440 T7438 arg2Of cord,and
R5983 T7440 T7439 arg1Of cord,spinal
R5984 T7443 T7441 arg2Of injury,after
R5985 T7443 T7442 arg1Of injury,traumatic
R5986 T7445 T7444 arg2Of 2,[
R5987 T7445 T7446 arg1Of 2,","
R5988 T7447 T7446 arg2Of 9,","
R5989 T7448 T7444 arg3Of ],[
R5990 T7452 T7449 arg2Of factor,As
R5991 T7452 T7450 arg1Of factor,a
R5992 T7452 T7451 arg1Of factor,transcript
R5993 T7454 T7455 arg1Of NF-κB,binds
R5994 T7454 T7463 arg1Of NF-κB,induces
R5995 T7455 T7456 arg1Of binds,with
R5996 T7455 T7458 arg1Of binds,once
R5997 T7455 T7462 arg1Of binds,and
R5998 T7457 T7456 arg2Of DNA,with
R5999 T7459 T7460 arg1Of it,was
R6000 T7459 T7461 arg2Of it,activated
R6001 T7461 T7458 arg2Of activated,once
R6002 T7461 T7460 arg2Of activated,was
R6003 T7462 T7449 arg1Of and,As
R6004 T7462 T7453 arg1Of and,","
R6005 T7463 T7462 arg2Of induces,and
R6006 T7464 T7463 arg2Of transcription,induces
R6007 T7464 T7465 arg1Of transcription,of
R6008 T7464 T7470 arg1Of transcription,of
R6009 T7466 T7467 arg1Of MMP9,and
R6010 T7467 T7465 arg2Of and,of
R6011 T7469 T7467 arg2Of battery,and
R6012 T7469 T7468 arg1Of battery,a
R6013 T7472 T7470 arg2Of cytokines,of
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R6017 T7475 T7476 arg1Of TNF-α,","
R6018 T7476 T7479 arg1Of ",",and
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R6020 T7479 T7474 arg2Of and,including
R6021 T7479 T7478 arg1Of and,","
R6022 T7479 T7481 arg1Of and,","
R6023 T7479 T7482 arg1Of and,in
R6024 T7479 T7485 arg1Of and,after
R6025 T7480 T7479 arg2Of IL-6,and
R6026 T7484 T7482 arg2Of tissues,in
R6027 T7484 T7483 arg1Of tissues,brain
R6028 T7486 T7485 arg2Of TBI,after
R6029 T7486 T7487 arg1Of TBI,[
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R6035 T7493 T7487 arg3Of ],[
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R6039 T7500 T7499 arg1Of injury,scratch
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R6041 T7501 T7497 arg2Of induced,revealed
R6042 T7501 T7498 arg1Of induced,that
R6043 T7502 T7501 arg2Of elevation,induced
R6044 T7502 T7503 arg1Of elevation,of
R6045 T7507 T7504 arg1Of activity,NF-κB
R6046 T7507 T7505 arg1Of activity,DNA
R6047 T7507 T7506 arg1Of activity,binding
R6048 T7507 T7508 arg1Of activity,","
R6049 T7508 T7513 arg1Of ",",and
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R6051 T7509 T7510 arg1Of overexpression,of
R6052 T7511 T7510 arg2Of MMP9,of
R6053 T7513 T7503 arg2Of and,of
R6054 T7513 T7512 arg1Of and,","
R6055 T7515 T7513 arg2Of mediators,and
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R6059 T7516 T7518 arg1Of mentioned,in
R6060 T7520 T7518 arg2Of astrocytes,in
R6061 T7520 T7519 arg2Of astrocytes,cultured
R6062 T7521 T7522 arg1Of It,has
R6063 T7521 T7523 arg1Of It,been
R6064 T7521 T7524 arg2Of It,demonstrated
R6065 T7524 T7522 arg2Of demonstrated,has
R6066 T7524 T7523 arg2Of demonstrated,been
R6067 T7526 T7527 arg1Of there,is
R6068 T7527 T7524 arg3Of is,demonstrated
R6069 T7527 T7525 arg1Of is,that
R6070 T7530 T7527 arg2Of loop,is
R6071 T7530 T7528 arg1Of loop,an
R6072 T7530 T7529 arg1Of loop,autoregulatory
R6073 T7530 T7531 arg1Of loop,among
R6074 T7534 T7531 arg2Of mediators,among
R6075 T7534 T7532 arg1Of mediators,these
R6076 T7534 T7533 arg1Of mediators,proinflammatory
R6077 T7536 T7535 arg2Of example,For
R6078 T7538 T7539 arg1Of TNF-α,and
R6079 T7539 T7541 arg1Of and,are
R6080 T7540 T7539 arg2Of IL-1β,and
R6081 T7541 T7554 arg1Of are,and
R6082 T7543 T7541 arg2Of stimulators,are
R6083 T7543 T7542 arg1Of stimulators,potent
R6084 T7543 T7544 arg1Of stimulators,for
R6085 T7543 T7546 arg1Of stimulators,in
R6086 T7545 T7544 arg2Of MMP9,for
R6087 T7547 T7546 arg2Of astrocytes,in
R6088 T7547 T7548 arg1Of astrocytes,[
R6089 T7549 T7550 arg1Of 12,","
R6090 T7550 T7548 arg2Of ",",[
R6091 T7551 T7550 arg2Of 13,","
R6092 T7552 T7548 arg3Of ],[
R6093 T7554 T7535 arg1Of and,For
R6094 T7554 T7537 arg1Of and,","
R6095 T7554 T7553 arg1Of and,","
R6096 T7555 T7556 arg1Of IL-6,induces
R6097 T7556 T7560 arg1Of induces,in
R6098 T7556 T7569 arg1Of induces,and
R6099 T7557 T7556 arg2Of overexpression,induces
R6100 T7557 T7558 arg1Of overexpression,of
R6101 T7559 T7558 arg2Of MMP9,of
R6102 T7564 T7560 arg2Of cells,in
R6103 T7564 T7561 arg1Of cells,human
R6104 T7564 T7562 arg1Of cells,colon
R6105 T7564 T7563 arg1Of cells,carcinoma
R6106 T7564 T7565 arg1Of cells,[
R6107 T7566 T7565 arg2Of 14,[
R6108 T7567 T7565 arg3Of ],[
R6109 T7569 T7554 arg2Of and,and
R6110 T7569 T7568 arg1Of and,","
R6111 T7570 T7571 arg1Of TNF-α,and
R6112 T7571 T7574 arg1Of and,can
R6113 T7571 T7575 arg1Of and,induce
R6114 T7572 T7571 arg2Of IL-1β,and
R6115 T7575 T7569 arg2Of induce,and
R6116 T7575 T7573 arg1Of induce,also
R6117 T7575 T7574 arg2Of induce,can
R6118 T7575 T7579 arg1Of induce,[
R6119 T7576 T7575 arg2Of activation,induce
R6120 T7576 T7577 arg1Of activation,of
R6121 T7578 T7577 arg2Of NF-κB,of
R6122 T7580 T7579 arg2Of 15,[
R6123 T7580 T7581 arg1Of 15,","
R6124 T7582 T7581 arg2Of 16,","
R6125 T7583 T7579 arg3Of ],[
R6126 T7586 T7584 arg1Of loop,This
R6127 T7586 T7585 arg1Of loop,autoregulatory
R6128 T7586 T7588 arg1Of loop,aggravates
R6129 T7586 T7595 arg1Of loop,induces
R6130 T7588 T7594 arg1Of aggravates,and
R6131 T7591 T7588 arg2Of effect,aggravates
R6132 T7591 T7589 arg1Of effect,the
R6133 T7591 T7590 arg1Of effect,damaging
R6134 T7591 T7592 arg1Of effect,of
R6135 T7593 T7592 arg2Of inflammation,of
R6136 T7594 T7587 arg1Of and,extremely
R6137 T7595 T7594 arg2Of induces,and
R6138 T7597 T7595 arg2Of injury,induces
R6139 T7597 T7596 arg1Of injury,secondary
R6140 T7597 T7598 arg1Of injury,to
R6141 T7599 T7598 arg2Of brain,to
R6142 T7600 T7601 arg1Of It,is
R6143 T7604 T7601 arg2Of choice,is
R6144 T7604 T7602 arg1Of choice,a
R6145 T7604 T7603 arg1Of choice,good
R6146 T7604 T7605 arg1Of choice,for
R6147 T7606 T7605 arg2Of targeting,for
R6148 T7606 T7607 arg1Of targeting,on
R6149 T7606 T7611 modOf targeting,to
R6150 T7610 T7606 arg2Of factor,targeting
R6151 T7610 T7608 arg1Of factor,an
R6152 T7610 T7609 arg1Of factor,upstream
R6153 T7612 T7611 arg1Of prevent,to
R6154 T7612 T7616 arg1Of prevent,after
R6155 T7615 T7612 arg2Of loop,prevent
R6156 T7615 T7613 arg1Of loop,such
R6157 T7615 T7614 arg1Of loop,autoregulatory
R6158 T7617 T7616 arg2Of TBI,after
R6159 T7619 T7618 arg1Of pathway,Nrf2-ARE
R6160 T7619 T7620 arg1Of pathway,has
R6161 T7619 T7621 arg1Of pathway,been
R6162 T7619 T7622 arg2Of pathway,proved
R6163 T7619 T7624 arg1Of pathway,be
R6164 T7622 T7620 arg2Of proved,has
R6165 T7622 T7621 arg2Of proved,been
R6166 T7624 T7622 arg3Of be,proved
R6167 T7624 T7623 arg1Of be,to
R6168 T7627 T7624 arg2Of regulator,be
R6169 T7627 T7625 arg1Of regulator,the
R6170 T7627 T7626 arg1Of regulator,key
R6171 T7627 T7628 arg1Of regulator,in
R6172 T7629 T7628 arg2Of reducing,in
R6173 T7631 T7630 arg1Of stress,oxidative
R6174 T7631 T7632 arg1Of stress,","
R6175 T7632 T7636 arg1Of ",",and
R6176 T7634 T7632 arg2Of damage,","
R6177 T7634 T7633 arg1Of damage,inflammatory
R6178 T7636 T7629 arg2Of and,reducing
R6179 T7636 T7635 arg1Of and,","
R6180 T7637 T7636 arg2Of accumulation,and
R6181 T7637 T7638 arg1Of accumulation,of
R6182 T7640 T7638 arg2Of metabolites,of
R6183 T7640 T7639 arg1Of metabolites,toxic
R6184 T7640 T7641 arg1Of metabolites,","
R6185 T7640 T7642 arg1Of metabolites,which
R6186 T7640 T7643 arg1Of metabolites,are
R6187 T7640 T7645 arg2Of metabolites,involved
R6188 T7645 T7643 arg2Of involved,are
R6189 T7645 T7644 arg1Of involved,all
R6190 T7645 T7646 arg1Of involved,in
R6191 T7647 T7646 arg2Of TBI,in
R6192 T7650 T7648 arg1Of study,Our
R6193 T7650 T7649 arg1Of study,previous
R6194 T7650 T7651 arg1Of study,has
R6195 T7650 T7652 arg1Of study,proved
R6196 T7652 T7651 arg2Of proved,has
R6197 T7652 T7660 arg1Of proved,after
R6198 T7654 T7652 arg2Of augmentation,proved
R6199 T7654 T7653 arg1Of augmentation,the
R6200 T7654 T7655 arg1Of augmentation,of
R6201 T7654 T7657 arg1Of augmentation,in
R6202 T7656 T7655 arg2Of Nrf2,of
R6203 T7659 T7657 arg2Of tissue,in
R6204 T7659 T7658 arg1Of tissue,brain
R6205 T7661 T7660 arg2Of TBI,after
R6206 T7661 T7662 arg1Of TBI,[
R6207 T7663 T7662 arg2Of 17,[
R6208 T7664 T7662 arg3Of ],[
R6209 T7666 T7665 arg2Of level,Enhanced
R6210 T7666 T7667 arg1Of level,of
R6211 T7666 T7669 arg1Of level,activates
R6212 T7668 T7667 arg2Of Nrf2,of
R6213 T7670 T7669 arg2Of transcription,activates
R6214 T7670 T7671 arg1Of transcription,of
R6215 T7670 T7677 arg1Of transcription,","
R6216 T7670 T7679 arg1Of transcription,as
R6217 T7673 T7671 arg2Of group,of
R6218 T7673 T7672 arg1Of group,a
R6219 T7673 T7674 arg1Of group,of
R6220 T7676 T7674 arg2Of genes,of
R6221 T7676 T7675 arg1Of genes,antioxidant
R6222 T7679 T7678 arg1Of as,such
R6223 T7681 T7680 arg1Of oxygenase-1,heme
R6224 T7681 T7682 arg1Of oxygenase-1,(
R6225 T7681 T7685 arg1Of oxygenase-1,and
R6226 T7683 T7682 arg2Of HO-1,(
R6227 T7684 T7682 arg3Of ),(
R6228 T7685 T7679 arg2Of and,as
R6229 T7685 T7691 arg1Of and,:
R6230 T7688 T7687 arg2Of P,(
R6231 T7689 T7687 arg3Of ),(
R6232 T7690 T7685 arg2Of H,and
R6233 T7690 T7686 arg1Of H,NAD
R6234 T7690 T7687 arg1Of H,(
R6235 T7693 T7691 arg2Of oxidoreductase-1,:
R6236 T7693 T7692 arg1Of oxidoreductase-1,quinone
R6237 T7693 T7694 arg1Of oxidoreductase-1,(
R6238 T7693 T7697 arg1Of oxidoreductase-1,","
R6239 T7693 T7698 arg1Of oxidoreductase-1,which
R6240 T7693 T7699 arg1Of oxidoreductase-1,would
R6241 T7693 T7701 arg1Of oxidoreductase-1,reduce
R6242 T7695 T7694 arg2Of NQO1,(
R6243 T7696 T7694 arg3Of ),(
R6244 T7701 T7699 arg2Of reduce,would
R6245 T7701 T7700 arg1Of reduce,subsequently
R6246 T7703 T7701 arg2Of damage,reduce
R6247 T7703 T7702 arg1Of damage,the
R6248 T7703 T7704 arg1Of damage,in
R6249 T7705 T7704 arg2Of brain,in
R6250 T7705 T7706 arg1Of brain,[
R6251 T7707 T7706 arg2Of 18,[
R6252 T7708 T7706 arg3Of ],[
R6253 T7710 T7709 arg1Of administration,Postinjury
R6254 T7710 T7711 arg1Of administration,of
R6255 T7710 T7720 arg1Of administration,improves
R6256 T7710 T7726 arg1Of administration,decreases
R6257 T7712 T7711 arg2Of SFN,of
R6258 T7712 T7713 arg1Of SFN,","
R6259 T7715 T7713 arg2Of inducer,","
R6260 T7715 T7714 arg1Of inducer,an
R6261 T7715 T7716 arg1Of inducer,of
R6262 T7717 T7716 arg2Of Nrf2,of
R6263 T7720 T7725 arg1Of improves,and
R6264 T7722 T7720 arg2Of memory,improves
R6265 T7722 T7721 arg1Of memory,spatial
R6266 T7722 T7723 arg1Of memory,of
R6267 T7724 T7723 arg2Of rat,of
R6268 T7725 T7718 arg1Of and,","
R6269 T7725 T7719 arg1Of and,significantly
R6270 T7726 T7725 arg2Of decreases,and
R6271 T7728 T7726 arg2Of immunoreactivity,decreases
R6272 T7728 T7727 arg1Of immunoreactivity,the
R6273 T7728 T7729 arg1Of immunoreactivity,for
R6274 T7728 T7740 arg1Of immunoreactivity,","
R6275 T7728 T7741 arg1Of immunoreactivity,in
R6276 T7730 T7729 arg2Of 4-Hydroxynonenal,for
R6277 T7730 T7731 arg1Of 4-Hydroxynonenal,(
R6278 T7730 T7734 arg1Of 4-Hydroxynonenal,","
R6279 T7732 T7731 arg2Of 4-HNE,(
R6280 T7733 T7731 arg3Of ),(
R6281 T7736 T7734 arg2Of marker,","
R6282 T7736 T7735 arg1Of marker,a
R6283 T7736 T7737 arg1Of marker,of
R6284 T7739 T7737 arg2Of peroxidation,of
R6285 T7739 T7738 arg1Of peroxidation,lipid
R6286 T7743 T7742 arg1Of cortex,the
R6287 T7743 T7744 arg1Of cortex,and
R6288 T7744 T7741 arg2Of and,in
R6289 T7747 T7744 arg2Of subfield,and
R6290 T7747 T7745 arg1Of subfield,the
R6291 T7747 T7746 arg1Of subfield,CA3
R6292 T7747 T7748 arg1Of subfield,of
R6293 T7747 T7750 arg1Of subfield,after
R6294 T7749 T7748 arg2Of hippocampus,of
R6295 T7751 T7750 arg2Of TBI,after
R6296 T7751 T7752 arg1Of TBI,[
R6297 T7753 T7752 arg2Of 19,[
R6298 T7754 T7752 arg3Of ],[
R6299 T7758 T7755 arg2Of hand,On
R6300 T7758 T7756 arg1Of hand,the
R6301 T7758 T7757 arg1Of hand,other
R6302 T7761 T7760 arg1Of mice,Nrf2-deficient
R6303 T7761 T7762 arg1Of mice,appear
R6304 T7761 T7764 arg1Of mice,susceptible
R6305 T7762 T7755 arg1Of appear,On
R6306 T7762 T7759 arg1Of appear,","
R6307 T7764 T7762 arg2Of susceptible,appear
R6308 T7764 T7763 arg1Of susceptible,more
R6309 T7764 T7765 arg1Of susceptible,to
R6310 T7766 T7765 arg2Of TBI,to
R6311 T7767 T7768 arg1Of Depletion,of
R6312 T7767 T7770 arg1Of Depletion,induces
R6313 T7769 T7768 arg2Of Nrf2,of
R6314 T7770 T7776 arg1Of induces,in
R6315 T7772 T7770 arg2Of expression,induces
R6316 T7772 T7771 arg1Of expression,higher
R6317 T7772 T7773 arg1Of expression,of
R6318 T7775 T7773 arg2Of mediators,of
R6319 T7775 T7774 arg1Of mediators,proinflammatory
R6320 T7777 T7776 arg2Of brain,in
R6321 T7777 T7778 arg1Of brain,after
R6322 T7779 T7778 arg2Of TBI,after
R6323 T7779 T7780 arg1Of TBI,[
R6324 T7781 T7780 arg2Of 20,[
R6325 T7782 T7780 arg3Of ],[
R6326 T7786 T7785 arg1Of results,our
R6327 T7786 T7787 arg1Of results,revealed
R6328 T7787 T7783 arg1Of revealed,Here
R6329 T7787 T7784 arg1Of revealed,","
R6330 T7789 T7790 arg1Of overexpression,of
R6331 T7789 T7802 arg1Of overexpression,was
R6332 T7789 T7804 arg2Of overexpression,aggravated
R6333 T7791 T7792 arg1Of TNF-α,","
R6334 T7792 T7794 arg1Of ",",","
R6335 T7793 T7792 arg2Of IL-1β,","
R6336 T7794 T7797 arg1Of ",",and
R6337 T7795 T7794 arg2Of IL-6,","
R6338 T7797 T7790 arg2Of and,of
R6339 T7797 T7796 arg1Of and,","
R6340 T7797 T7799 arg1Of and,after
R6341 T7798 T7797 arg2Of MMP9,and
R6342 T7801 T7799 arg2Of injury,after
R6343 T7801 T7800 arg1Of injury,scratch
R6344 T7804 T7802 arg2Of aggravated,was
R6345 T7804 T7803 arg1Of aggravated,more
R6346 T7804 T7805 arg1Of aggravated,in
R6347 T7804 T7810 arg1Of aggravated,than
R6348 T7804 T7814 arg1Of aggravated,for
R6349 T7804 T7819 arg1Of aggravated,and
R6350 T7809 T7805 arg2Of astrocytes,in
R6351 T7809 T7806 arg2Of astrocytes,cultured
R6352 T7809 T7807 arg1Of astrocytes,Nrf2
R6353 T7809 T7808 arg1Of astrocytes,knockout
R6354 T7811 T7810 arg2Of in,than
R6355 T7813 T7811 arg2Of astrocyetes,in
R6356 T7813 T7812 arg1Of astrocyetes,wildtype
R6357 T7817 T7814 arg2Of time,for
R6358 T7817 T7815 arg1Of time,the
R6359 T7817 T7816 arg1Of time,first
R6360 T7819 T7787 arg2Of and,revealed
R6361 T7819 T7788 arg1Of and,that
R6362 T7819 T7818 arg1Of and,","
R6363 T7820 T7821 arg1Of overexpression,of
R6364 T7820 T7825 arg1Of overexpression,led
R6365 T7824 T7821 arg2Of mediators,of
R6366 T7824 T7822 arg1Of mediators,these
R6367 T7824 T7823 arg1Of mediators,proinflammatory
R6368 T7825 T7819 arg2Of led,and
R6369 T7825 T7826 arg1Of led,to
R6370 T7829 T7826 arg2Of deaths,to
R6371 T7829 T7827 arg1Of deaths,more
R6372 T7829 T7828 arg1Of deaths,astrocytes
R6373 T7830 T7831 arg2Of Data,obtained
R6374 T7830 T7835 arg1Of Data,suggest
R6375 T7831 T7832 arg1Of obtained,from
R6376 T7834 T7832 arg2Of studies,from
R6377 T7834 T7833 arg1Of studies,animal
R6378 T7837 T7835 arg2Of possibility,suggest
R6379 T7837 T7836 arg1Of possibility,the
R6380 T7840 T7839 arg1Of effect,antioxidant
R6381 T7840 T7841 arg1Of effect,of
R6382 T7840 T7843 arg1Of effect,may
R6383 T7840 T7844 arg1Of effect,be
R6384 T7840 T7845 arg2Of effect,achieved
R6385 T7842 T7841 arg2Of Nrf2,of
R6386 T7845 T7837 arg2Of achieved,possibility
R6387 T7845 T7838 arg1Of achieved,that
R6388 T7845 T7843 arg2Of achieved,may
R6389 T7845 T7844 arg2Of achieved,be
R6390 T7847 T7845 arg1Of suppression,achieved
R6391 T7847 T7846 arg2Of suppression,by
R6392 T7847 T7848 arg1Of suppression,of
R6393 T7850 T7848 arg2Of pathways,of
R6394 T7850 T7849 arg1Of pathways,proinflammatory
R6395 T7850 T7851 arg1Of pathways,which
R6396 T7850 T7852 arg1Of pathways,are
R6397 T7850 T7853 arg2Of pathways,mediated
R6398 T7853 T7852 arg2Of mediated,are
R6399 T7856 T7853 arg1Of signaling,mediated
R6400 T7856 T7854 arg2Of signaling,by
R6401 T7856 T7855 arg1Of signaling,NF-κB
R6402 T7857 T7858 arg1Of Administration,of
R6403 T7857 T7860 arg1Of Administration,is
R6404 T7857 T7861 arg2Of Administration,found
R6405 T7857 T7863 arg1Of Administration,be
R6406 T7857 T7864 arg1Of Administration,able
R6407 T7857 T7866 arg1Of Administration,inhibit
R6408 T7857 T7877 arg1Of Administration,alleviating
R6409 T7859 T7858 arg2Of SFN,of
R6410 T7861 T7860 arg2Of found,is
R6411 T7863 T7861 arg3Of be,found
R6412 T7863 T7862 arg1Of be,to
R6413 T7864 T7863 arg2Of able,be
R6414 T7866 T7864 arg2Of inhibit,able
R6415 T7866 T7865 arg1Of inhibit,to
R6416 T7866 T7875 arg1Of inhibit,","
R6417 T7866 T7877 modOf inhibit,alleviating
R6418 T7868 T7867 arg1Of phosphorylation,IKK/IκB
R6419 T7868 T7869 arg1Of phosphorylation,and
R6420 T7869 T7866 arg2Of and,inhibit
R6421 T7874 T7869 arg2Of translocation,and
R6422 T7874 T7870 arg1Of translocation,p65
R6423 T7874 T7871 arg1Of translocation,NF-κB
R6424 T7874 T7872 arg1Of translocation,subunit
R6425 T7874 T7873 arg1Of translocation,nuclear
R6426 T7877 T7876 arg1Of alleviating,consequently
R6427 T7879 T7877 arg2Of signaling,alleviating
R6428 T7879 T7878 arg1Of signaling,NF-κB
R6429 T7879 T7880 arg1Of signaling,[
R6430 T7881 T7880 arg2Of 21,[
R6431 T7882 T7880 arg3Of ],[
R6432 T7885 T7884 arg1Of activation,NF-κB
R6433 T7885 T7886 arg2Of activation,induced
R6434 T7885 T7892 arg1Of activation,could
R6435 T7885 T7893 arg1Of activation,be
R6436 T7885 T7894 arg2Of activation,attenuated
R6437 T7888 T7886 arg1Of lipopolysaccharide,induced
R6438 T7888 T7887 arg2Of lipopolysaccharide,by
R6439 T7888 T7889 arg1Of lipopolysaccharide,(
R6440 T7890 T7889 arg2Of LPS,(
R6441 T7891 T7889 arg3Of ),(
R6442 T7894 T7883 arg1Of attenuated,And
R6443 T7894 T7892 arg2Of attenuated,could
R6444 T7894 T7893 arg2Of attenuated,be
R6445 T7894 T7908 arg1Of attenuated,[
R6446 T7898 T7894 arg1Of activators,attenuated
R6447 T7898 T7895 arg2Of activators,by
R6448 T7898 T7896 arg1Of activators,diverse
R6449 T7898 T7897 arg1Of activators,Nrf2
R6450 T7898 T7899 arg1Of activators,","
R6451 T7898 T7901 arg1Of activators,as
R6452 T7901 T7900 arg1Of as,such
R6453 T7902 T7903 arg1Of SFN,and
R6454 T7903 T7901 arg2Of and,as
R6455 T7903 T7905 arg1Of and,(
R6456 T7904 T7903 arg2Of curcumin,and
R6457 T7906 T7905 arg2Of CUR,(
R6458 T7907 T7905 arg3Of ),(
R6459 T7909 T7908 arg2Of 22,[
R6460 T7910 T7908 arg3Of ],[
R6461 T7915 T7913 arg1Of studies,our
R6462 T7915 T7914 arg1Of studies,previous
R6463 T7915 T7916 arg1Of studies,indicate
R6464 T7916 T7911 arg1Of indicate,Furthermore
R6465 T7916 T7912 arg1Of indicate,","
R6466 T7918 T7919 arg1Of depletion,of
R6467 T7918 T7921 arg1Of depletion,induces
R6468 T7920 T7919 arg2Of Nrf2,of
R6469 T7921 T7916 arg2Of induces,indicate
R6470 T7921 T7917 arg1Of induces,that
R6471 T7922 T7921 arg2Of augmentation,induces
R6472 T7922 T7923 arg1Of augmentation,of
R6473 T7922 T7929 arg1Of augmentation,in
R6474 T7922 T7936 arg1Of augmentation,after
R6475 T7925 T7924 arg1Of activity,NF-κB
R6476 T7925 T7926 arg1Of activity,and
R6477 T7926 T7923 arg2Of and,of
R6478 T7928 T7926 arg2Of response,and
R6479 T7928 T7927 arg1Of response,inflammatory
R6480 T7930 T7931 arg1Of lung,","
R6481 T7931 T7934 arg1Of ",",and
R6482 T7932 T7931 arg2Of brain,","
R6483 T7934 T7929 arg2Of and,in
R6484 T7934 T7933 arg1Of and,","
R6485 T7935 T7934 arg2Of intestine,and
R6486 T7937 T7936 arg2Of TBI,after
R6487 T7937 T7938 arg1Of TBI,[
R6488 T7939 T7940 arg1Of 4,","
R6489 T7940 T7938 arg2Of ",",[
R6490 T7940 T7942 arg1Of ",",","
R6491 T7941 T7940 arg2Of 5,","
R6492 T7943 T7942 arg2Of 23,","
R6493 T7944 T7938 arg3Of ],[
R6494 T7945 T7946 arg1Of Results,from
R6495 T7945 T7950 arg1Of Results,confirmed
R6496 T7948 T7946 arg2Of study,from
R6497 T7948 T7947 arg1Of study,this
R6498 T7950 T7949 arg1Of confirmed,further
R6499 T7952 T7951 arg1Of relationship,such
R6500 T7952 T7953 arg1Of relationship,existed
R6501 T7953 T7950 arg2Of existed,confirmed
R6502 T7953 T7954 arg1Of existed,in
R6503 T7953 T7957 arg1Of existed,after
R6504 T7956 T7954 arg2Of astrocytes,in
R6505 T7956 T7955 arg2Of astrocytes,cultured
R6506 T7959 T7957 arg2Of injury,after
R6507 T7959 T7958 arg1Of injury,scratch
R6508 T7961 T7960 arg2Of activation,Enhanced
R6509 T7961 T7962 arg1Of activation,of
R6510 T7961 T7964 arg1Of activation,is
R6511 T7961 T7966 arg2Of activation,discovered
R6512 T7963 T7962 arg2Of NF-κB,of
R6513 T7966 T7964 arg2Of discovered,is
R6514 T7966 T7965 arg1Of discovered,also
R6515 T7966 T7967 arg1Of discovered,in
R6516 T7966 T7979 arg1Of discovered,after
R6517 T7966 T7982 arg1Of discovered,[
R6518 T7968 T7969 arg1Of lung,","
R6519 T7969 T7972 arg1Of ",",and
R6520 T7970 T7969 arg2Of macrophages,","
R6521 T7972 T7967 arg2Of and,in
R6522 T7972 T7971 arg1Of and,","
R6523 T7975 T7972 arg2Of fibroblasts,and
R6524 T7975 T7973 arg1Of fibroblasts,mouse
R6525 T7975 T7974 arg1Of fibroblasts,embryonic
R6526 T7975 T7976 arg1Of fibroblasts,of
R6527 T7978 T7976 arg2Of mice,of
R6528 T7978 T7977 arg1Of mice,Nrf2-deficient
R6529 T7981 T7979 arg2Of sepsis,after
R6530 T7981 T7980 arg1Of sepsis,experimental
R6531 T7983 T7982 arg2Of 24,[
R6532 T7984 T7982 arg3Of ],[
R6533 T7987 T7988 arg1Of it,is
R6534 T7987 T7989 arg2Of it,reported
R6535 T7989 T7985 arg1Of reported,Interestingly
R6536 T7989 T7986 arg1Of reported,","
R6537 T7989 T7988 arg2Of reported,is
R6538 T7991 T7992 arg1Of NF-κB,can
R6539 T7991 T7993 arg1Of NF-κB,inhibit
R6540 T7993 T7989 arg3Of inhibit,reported
R6541 T7993 T7990 arg1Of inhibit,that
R6542 T7993 T7992 arg2Of inhibit,can
R6543 T7993 T7995 arg1Of inhibit,at
R6544 T7994 T7993 arg2Of Nrf2,inhibit
R6545 T7997 T7995 arg2Of level,at
R6546 T7997 T7996 arg1Of level,transcriptional
R6547 T8000 T7998 arg1Of subunit,NF-κB
R6548 T8000 T7999 arg1Of subunit,p65
R6549 T8000 T8001 arg1Of subunit,repressed
R6550 T8001 T8008 arg1Of repressed,by
R6551 T8004 T8001 arg2Of pathway,repressed
R6552 T8004 T8002 arg1Of pathway,the
R6553 T8004 T8003 arg1Of pathway,Nrf2-ARE
R6554 T8004 T8005 arg1Of pathway,at
R6555 T8007 T8005 arg2Of level,at
R6556 T8007 T8006 arg1Of level,transcriptional
R6557 T8010 T8009 arg1Of interaction,competitive
R6558 T8010 T8011 arg1Of interaction,with
R6559 T8010 T8017 arg1Of interaction,or
R6560 T8014 T8011 arg2Of domain,with
R6561 T8014 T8012 arg1Of domain,the
R6562 T8014 T8013 arg1Of domain,CH1-KIX
R6563 T8014 T8015 arg1Of domain,of
R6564 T8016 T8015 arg2Of CBP,of
R6565 T8017 T8008 arg2Of or,by
R6566 T8020 T8017 arg2Of hypoacetylation,or
R6567 T8020 T8018 arg1Of hypoacetylation,local
R6568 T8020 T8019 arg1Of hypoacetylation,histone
R6569 T8020 T8021 arg1Of hypoacetylation,[
R6570 T8022 T8021 arg2Of 25,[
R6571 T8023 T8021 arg3Of ],[
R6572 T8026 T8024 arg1Of findings,All
R6573 T8026 T8025 arg1Of findings,these
R6574 T8026 T8027 arg1Of findings,indicate
R6575 T8031 T8027 arg2Of crosstalk,indicate
R6576 T8031 T8028 arg1Of crosstalk,the
R6577 T8031 T8029 arg1Of crosstalk,potential
R6578 T8031 T8030 arg1Of crosstalk,complicate
R6579 T8031 T8032 arg1Of crosstalk,between
R6580 T8033 T8034 arg1Of NF-κB,and
R6581 T8034 T8032 arg2Of and,between
R6582 T8034 T8036 arg1Of and,","
R6583 T8034 T8037 arg1Of and,which
R6584 T8034 T8038 arg1Of and,may
R6585 T8034 T8039 arg1Of and,be
R6586 T8034 T8040 arg2Of and,regulated
R6587 T8035 T8034 arg2Of Nrf2,and
R6588 T8040 T8038 arg2Of regulated,may
R6589 T8040 T8039 arg2Of regulated,be
R6590 T8040 T8051 arg1Of regulated,[
R6591 T8046 T8044 arg1Of kinase,mitogen-activated
R6592 T8046 T8045 arg1Of kinase,protein
R6593 T8046 T8047 arg1Of kinase,(
R6594 T8048 T8047 arg2Of MAPKs,(
R6595 T8049 T8047 arg3Of ),(
R6596 T8050 T8040 arg1Of pathway,regulated
R6597 T8050 T8041 arg2Of pathway,by
R6598 T8050 T8042 arg1Of pathway,the
R6599 T8050 T8043 arg1Of pathway,upstream
R6600 T8050 T8046 arg1Of pathway,kinase
R6601 T8052 T8051 arg2Of 26,[
R6602 T8053 T8051 arg3Of ],[
R6603 T8057 T8055 arg2Of confirmed,has
R6604 T8057 T8056 arg2Of confirmed,been
R6605 T8059 T8060 arg1Of Nrf2,is
R6606 T8059 T8062 arg2Of Nrf2,detected
R6607 T8062 T8054 arg1Of detected,It
R6608 T8062 T8055 arg1Of detected,has
R6609 T8062 T8056 arg1Of detected,been
R6610 T8062 T8057 arg2Of detected,confirmed
R6611 T8062 T8058 arg1Of detected,that
R6612 T8062 T8060 arg2Of detected,is
R6613 T8062 T8061 arg1Of detected,mainly
R6614 T8062 T8063 arg1Of detected,in
R6615 T8064 T8063 arg2Of nucleus,in
R6616 T8064 T8065 arg1Of nucleus,of
R6617 T8066 T8065 arg2Of astrocytes,of
R6618 T8066 T8067 arg1Of astrocytes,after
R6619 T8068 T8067 arg2Of TBI,after
R6620 T8068 T8069 arg1Of TBI,[
R6621 T8070 T8069 arg2Of 18,[
R6622 T8071 T8069 arg3Of ],[
R6623 T8073 T8072 arg2Of view,In
R6624 T8073 T8074 arg1Of view,of
R6625 T8076 T8074 arg2Of fact,of
R6626 T8076 T8075 arg1Of fact,the
R6627 T8078 T8079 arg1Of Nrf2,is
R6628 T8079 T8076 arg2Of is,fact
R6629 T8079 T8077 arg1Of is,that
R6630 T8082 T8079 arg2Of factor,is
R6631 T8082 T8080 arg1Of factor,a
R6632 T8082 T8081 arg1Of factor,transcription
R6633 T8082 T8083 arg1Of factor,which
R6634 T8082 T8084 arg1Of factor,should
R6635 T8082 T8085 arg1Of factor,take
R6636 T8085 T8084 arg2Of take,should
R6637 T8085 T8088 arg1Of take,in
R6638 T8086 T8085 arg2Of function,take
R6639 T8088 T8087 arg1Of in,mainly
R6640 T8089 T8088 arg2Of nucleus,in
R6641 T8091 T8092 arg1Of it,can
R6642 T8091 T8093 arg1Of it,be
R6643 T8091 T8094 arg2Of it,reasoned
R6644 T8094 T8072 arg1Of reasoned,In
R6645 T8094 T8090 arg1Of reasoned,","
R6646 T8094 T8092 arg2Of reasoned,can
R6647 T8094 T8093 arg2Of reasoned,be
R6648 T8096 T8097 arg1Of astrocytes,may
R6649 T8096 T8098 arg1Of astrocytes,be
R6650 T8098 T8094 arg3Of be,reasoned
R6651 T8098 T8095 arg1Of be,that
R6652 T8098 T8097 arg2Of be,may
R6653 T8098 T8104 arg1Of be,in
R6654 T8100 T8098 arg2Of kind,be
R6655 T8100 T8099 arg1Of kind,one
R6656 T8100 T8101 arg1Of kind,of
R6657 T8103 T8101 arg2Of cells,of
R6658 T8103 T8102 arg1Of cells,respondent
R6659 T8105 T8104 arg2Of activation,in
R6660 T8105 T8106 arg1Of activation,of
R6661 T8108 T8106 arg2Of pathway,of
R6662 T8108 T8107 arg1Of pathway,Nrf2-ARE
R6663 T8108 T8109 arg1Of pathway,after
R6664 T8110 T8109 arg2Of TBI,after
R6665 T8112 T8111 arg1Of study,Previous
R6666 T8112 T8113 arg1Of study,identified
R6667 T8113 T8126 arg1Of identified,after
R6668 T8115 T8113 arg2Of expression,identified
R6669 T8115 T8114 arg1Of expression,the
R6670 T8115 T8116 arg1Of expression,of
R6671 T8115 T8123 arg1Of expression,in
R6672 T8117 T8118 arg1Of TNF-α,","
R6673 T8118 T8121 arg1Of ",",and
R6674 T8119 T8118 arg2Of IL-1β,","
R6675 T8121 T8116 arg2Of and,of
R6676 T8121 T8120 arg1Of and,","
R6677 T8122 T8121 arg2Of IL-6,and
R6678 T8125 T8123 arg2Of astrocytes,in
R6679 T8125 T8124 arg2Of astrocytes,cultured
R6680 T8127 T8126 arg2Of treatment,after
R6681 T8127 T8128 arg1Of treatment,with
R6682 T8129 T8130 arg1Of LPS,or
R6683 T8130 T8128 arg2Of or,with
R6684 T8130 T8132 arg1Of or,[
R6685 T8131 T8130 arg2Of oxyhemoglobin,or
R6686 T8133 T8132 arg2Of 27,[
R6687 T8133 T8134 arg1Of 27,","
R6688 T8135 T8134 arg2Of 28,","
R6689 T8136 T8132 arg3Of ],[
R6690 T8138 T8137 arg1Of study,Another
R6691 T8138 T8139 arg1Of study,revealed
R6692 T8145 T8141 arg2Of occlusion,after
R6693 T8145 T8142 arg1Of occlusion,middle
R6694 T8145 T8143 arg1Of occlusion,cerebral
R6695 T8145 T8144 arg1Of occlusion,artery
R6696 T8148 T8147 arg1Of astrocytes,MMP9-positive
R6697 T8148 T8149 arg1Of astrocytes,were
R6698 T8148 T8150 arg2Of astrocytes,observed
R6699 T8150 T8139 arg2Of observed,revealed
R6700 T8150 T8140 arg1Of observed,that
R6701 T8150 T8141 arg1Of observed,after
R6702 T8150 T8146 arg1Of observed,","
R6703 T8150 T8149 arg2Of observed,were
R6704 T8150 T8151 arg1Of observed,in
R6705 T8150 T8154 arg1Of observed,by
R6706 T8150 T8156 arg1Of observed,[
R6707 T8153 T8151 arg2Of tissues,in
R6708 T8153 T8152 arg1Of tissues,brain
R6709 T8155 T8154 arg2Of immunohistochemistry,by
R6710 T8157 T8156 arg2Of 29,[
R6711 T8158 T8156 arg3Of ],[
R6712 T8160 T8159 arg1Of results,Those
R6713 T8160 T8161 arg1Of results,indicate
R6714 T8161 T8169 arg1Of indicate,after
R6715 T8163 T8161 arg2Of role,indicate
R6716 T8163 T8162 arg1Of role,the
R6717 T8163 T8164 arg1Of role,of
R6718 T8163 T8166 arg1Of role,in
R6719 T8165 T8164 arg2Of astrocytes,of
R6720 T8168 T8166 arg2Of process,in
R6721 T8168 T8167 arg1Of process,inflammatory
R6722 T8171 T8169 arg2Of injury,after
R6723 T8171 T8170 arg1Of injury,brain
R6724 T8174 T8177 modOf now,is
R6725 T8174 T8180 arg1Of now,focused
R6726 T8176 T8177 arg1Of there,is
R6727 T8177 T8175 arg1Of is,","
R6728 T8179 T8177 arg2Of study,is
R6729 T8179 T8178 arg1Of study,no
R6730 T8180 T8172 arg1Of focused,But
R6731 T8180 T8173 arg1Of focused,till
R6732 T8180 T8181 arg1Of focused,on
R6733 T8180 T8192 arg1Of focused,after
R6734 T8183 T8181 arg2Of relationship,on
R6735 T8183 T8182 arg1Of relationship,the
R6736 T8183 T8184 arg1Of relationship,among
R6737 T8185 T8186 arg1Of astrocytes,","
R6738 T8186 T8189 arg1Of ",",and
R6739 T8187 T8186 arg2Of Nrf2,","
R6740 T8189 T8184 arg2Of and,among
R6741 T8189 T8188 arg1Of and,","
R6742 T8191 T8189 arg2Of mediators,and
R6743 T8191 T8190 arg1Of mediators,proinflammatory
R6744 T8193 T8192 arg2Of TBI,after
R6745 T8195 T8194 arg1Of results,Our
R6746 T8195 T8196 arg1Of results,demonstrated
R6747 T8199 T8196 arg2Of expression,demonstrated
R6748 T8199 T8197 arg1Of expression,the
R6749 T8199 T8198 arg2Of expression,upregulated
R6750 T8199 T8200 arg1Of expression,of
R6751 T8199 T8209 arg1Of expression,in
R6752 T8201 T8202 arg1Of TNF-α,","
R6753 T8202 T8204 arg1Of ",",","
R6754 T8203 T8202 arg2Of IL-1β,","
R6755 T8204 T8207 arg1Of ",",and
R6756 T8205 T8204 arg2Of IL-6,","
R6757 T8207 T8200 arg2Of and,of
R6758 T8207 T8206 arg1Of and,","
R6759 T8208 T8207 arg2Of MMP9,and
R6760 T8212 T8209 arg2Of astrocytes,in
R6761 T8212 T8210 arg1Of astrocytes,Nrf2
R6762 T8212 T8211 arg1Of astrocytes,knockout
R6763 T8212 T8213 arg1Of astrocytes,after
R6764 T8215 T8213 arg2Of injury,after
R6765 T8215 T8214 arg1Of injury,scratch
R6766 T8215 T8216 arg1Of injury,for
R6767 T8219 T8216 arg2Of time,for
R6768 T8219 T8217 arg1Of time,the
R6769 T8219 T8218 arg1Of time,first
R6770 T8221 T8220 arg2Of conclusion,In
R6771 T8223 T8224 arg1Of depletion,of
R6772 T8223 T8226 arg1Of depletion,induced
R6773 T8225 T8224 arg2Of Nrf2,of
R6774 T8226 T8220 arg1Of induced,In
R6775 T8226 T8222 arg1Of induced,","
R6776 T8226 T8243 modOf induced,resulting
R6777 T8228 T8227 arg1Of activation,the
R6778 T8228 T8229 arg1Of activation,of
R6779 T8228 T8231 arg1Of activation,and
R6780 T8230 T8229 arg2Of NF-κB,of
R6781 T8231 T8226 arg2Of and,induced
R6782 T8233 T8231 arg2Of expression,and
R6783 T8233 T8232 arg1Of expression,the
R6784 T8233 T8234 arg1Of expression,of
R6785 T8235 T8236 arg1Of TNF-α,","
R6786 T8236 T8238 arg1Of ",",","
R6787 T8237 T8236 arg2Of IL-1β,","
R6788 T8238 T8241 arg1Of ",",and
R6789 T8239 T8238 arg2Of IL-6,","
R6790 T8241 T8234 arg2Of and,of
R6791 T8241 T8240 arg1Of and,","
R6792 T8242 T8241 arg2Of MMP9,and
R6793 T8243 T8244 arg1Of resulting,in
R6794 T8247 T8244 arg2Of deaths,in
R6795 T8247 T8245 arg1Of deaths,more
R6796 T8247 T8246 arg1Of deaths,cell
R6797 T8247 T8248 arg1Of deaths,in
R6798 T8249 T8248 arg2Of astrocytes,in
R6799 T8249 T8250 arg1Of astrocytes,after
R6800 T8252 T8250 arg2Of injury,after
R6801 T8252 T8251 arg1Of injury,scratch
R6802 T8254 T8253 arg1Of results,These
R6803 T8254 T8255 arg1Of results,suggest
R6804 T8257 T8258 arg1Of Nrf2,may
R6805 T8257 T8259 arg1Of Nrf2,be
R6806 T8259 T8255 arg2Of be,suggest
R6807 T8259 T8256 arg1Of be,that
R6808 T8259 T8258 arg2Of be,may
R6809 T8262 T8259 arg2Of target,be
R6810 T8262 T8260 arg1Of target,an
R6811 T8262 T8261 arg1Of target,important
R6812 T8262 T8263 arg1Of target,for
R6813 T8262 T8266 arg1Of target,after
R6814 T8265 T8263 arg2Of therapy,for
R6815 T8265 T8264 arg1Of therapy,anti-inflammatory
R6816 T8267 T8266 arg2Of TBI,after