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PMC:3317373 / 1291-20739 JSONTXT 26 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T640 16-21 NN denotes Brain
T641 22-28 NN denotes damage
T642 29-38 VB denotes following
T643 39-48 JJ denotes traumatic
T644 49-55 NN denotes injury
T645 56-58 VB denotes is
T646 59-60 DT denotes a
T647 61-67 NN denotes result
T648 68-70 IN denotes of
T649 71-77 JJ denotes direct
T650 78-79 -LRB- denotes (
T651 79-86 JJ denotes primary
T652 87-93 NN denotes injury
T653 93-94 -RRB- denotes )
T654 95-98 CC denotes and
T655 99-107 JJ denotes indirect
T656 108-109 -LRB- denotes (
T657 109-118 JJ denotes secondary
T658 119-121 CC denotes or
T659 122-129 VB denotes delayed
T660 130-136 NN denotes injury
T661 136-137 -RRB- denotes )
T662 138-148 NN denotes mechanisms
T663 150-153 DT denotes The
T664 154-163 JJ denotes secondary
T665 164-170 NN denotes injury
T666 171-180 NN denotes mechanism
T667 181-189 VB denotes involves
T668 190-193 DT denotes the
T669 194-204 NN denotes initiation
T670 205-207 IN denotes of
T671 208-210 DT denotes an
T672 211-216 JJ denotes acute
T673 217-229 JJ denotes inflammatory
T674 230-238 NN denotes response
T675 238-239 -COMMA- denotes ,
T676 240-249 VB denotes including
T677 250-259 NN denotes breakdown
T678 260-262 IN denotes of
T679 263-274 NN denotes blood-brain
T680 275-282 NN denotes barrier
T681 283-284 -LRB- denotes (
T682 284-287 NN denotes BBB
T683 287-288 -RRB- denotes )
T684 288-289 -COMMA- denotes ,
T685 290-295 NN denotes brain
T686 296-301 NN denotes edema
T687 301-302 -COMMA- denotes ,
T688 303-315 NN denotes infiltration
T689 316-318 IN denotes of
T690 319-329 JJ denotes peripheral
T691 330-335 NN denotes blood
T692 336-341 NN denotes cells
T693 341-342 -COMMA- denotes ,
T694 343-346 CC denotes and
T695 347-357 NN denotes activation
T696 358-360 IN denotes of
T697 361-369 JJ denotes resident
T698 370-385 JJ denotes immunocompetent
T699 386-391 NN denotes cells
T700 391-392 -COMMA- denotes ,
T701 393-395 RB denotes as
T702 396-400 RB denotes well
T703 401-403 IN denotes as
T704 404-407 DT denotes the
T705 408-415 NN denotes release
T706 416-418 IN denotes of
T707 419-427 JJ denotes numerous
T708 428-434 JJ denotes immune
T709 435-444 NN denotes mediators
T710 445-449 JJ denotes such
T711 450-452 IN denotes as
T712 453-465 NN denotes interleukins
T713 466-469 CC denotes and
T714 470-481 JJ denotes chemotactic
T715 482-489 NN denotes factors
T716 490-491 -LRB- denotes [
T717 491-492 CD denotes 1
T718 492-493 -RRB- denotes ]
T719 495-498 CC denotes And
T720 499-502 DT denotes the
T721 503-513 JJ denotes subsequent
T722 514-526 NN denotes inflammation
T723 527-532 VB denotes leads
T724 533-535 TO denotes to
T725 536-545 JJ denotes secondary
T726 546-552 NN denotes damage
T727 553-556 RB denotes not
T728 557-561 RB denotes only
T729 562-564 IN denotes in
T730 565-570 NN denotes brain
T731 571-574 CC denotes but
T732 575-579 RB denotes also
T733 580-582 IN denotes in
T734 583-588 JJ denotes other
T735 589-595 NN denotes organs
T736 596-597 -LRB- denotes [
T737 597-600 CD denotes 2–4
T738 600-601 -RRB- denotes ]
T739 603-610 JJ denotes Nuclear
T740 611-617 NN denotes factor
T741 618-627 JJ denotes erythroid
T742 628-637 JJ denotes 2-related
T743 638-645 NN denotes factor2
T744 646-647 -LRB- denotes (
T745 647-651 NN denotes Nrf2
T746 651-652 -RRB- denotes )
T747 653-655 VB denotes is
T748 656-657 DT denotes a
T749 658-671 NN denotes transcription
T750 672-678 NN denotes factor
T751 679-683 WDT denotes that
T752 684-693 VB denotes regulates
T753 694-698 JJ denotes many
T754 699-704 NN denotes kinds
T755 705-707 IN denotes of
T756 708-719 JJ denotes antioxidant
T757 720-725 NN denotes genes
T758 727-734 JJ denotes Several
T759 735-742 NN denotes studies
T760 743-747 VB denotes have
T761 748-760 VB denotes demonstrated
T762 761-765 IN denotes that
T763 766-770 NN denotes Nrf2
T764 771-780 VB denotes regulates
T765 781-784 DT denotes the
T766 785-797 NN denotes inflammation
T767 798-800 IN denotes in
T768 801-804 DT denotes the
T769 805-810 NN denotes brain
T770 811-816 IN denotes after
T771 817-826 JJ denotes traumatic
T772 827-832 NN denotes brain
T773 833-839 NN denotes injury
T774 840-841 -LRB- denotes (
T775 841-844 NN denotes TBI
T776 844-845 -RRB- denotes )
T777 847-849 PRP denotes It
T778 850-853 VB denotes was
T779 854-858 RB denotes also
T780 859-865 VB denotes showed
T781 866-870 IN denotes that
T782 871-874 NN denotes TBI
T783 875-880 MD denotes could
T784 881-887 VB denotes induce
T785 888-892 RB denotes more
T786 893-903 JJ denotes aggravated
T787 904-910 NN denotes damage
T788 911-913 IN denotes in
T789 914-918 NN denotes Nrf2
T790 919-927 NN denotes knockout
T791 928-932 NN denotes mice
T792 933-937 IN denotes than
T793 938-940 IN denotes in
T794 941-949 JJ denotes wildtype
T795 950-954 NN denotes mice
T796 955-956 -LRB- denotes [
T797 956-957 CD denotes 5
T798 957-958 -RRB- denotes ]
T799 960-962 IN denotes On
T800 963-966 DT denotes the
T801 967-975 NN denotes contrary
T802 975-976 -COMMA- denotes ,
T803 977-981 JJ denotes such
T804 982-994 NN denotes inflammation
T805 995-998 MD denotes can
T806 999-1001 VB denotes be
T807 1002-1012 VB denotes extenuated
T808 1013-1020 IN denotes through
T809 1021-1030 VB denotes elevating
T810 1031-1034 DT denotes the
T811 1035-1040 NN denotes level
T812 1041-1043 IN denotes of
T813 1044-1048 NN denotes Nrf2
T814 1049-1051 IN denotes by
T815 1052-1055 PRP-DOLLAR- denotes its
T816 1056-1064 NN denotes inducers
T817 1064-1065 -COMMA- denotes ,
T818 1066-1070 JJ denotes such
T819 1071-1073 IN denotes as
T820 1074-1086 NN denotes sulforaphane
T821 1087-1088 -LRB- denotes (
T822 1088-1091 NN denotes SFN
T823 1091-1092 -RRB- denotes )
T824 1093-1094 -LRB- denotes [
T825 1094-1095 CD denotes 6
T826 1095-1096 -RRB- denotes ]
T827 1098-1100 PRP denotes It
T828 1101-1103 VB denotes is
T829 1104-1108 RB denotes well
T830 1109-1119 VB denotes documented
T831 1120-1124 IN denotes that
T832 1125-1135 NN denotes astrocytes
T833 1136-1140 VB denotes play
T834 1141-1142 DT denotes a
T835 1143-1151 JJ denotes critical
T836 1152-1156 NN denotes role
T837 1157-1159 IN denotes in
T838 1160-1171 VB denotes maintaining
T839 1172-1178 JJ denotes normal
T840 1179-1184 NN denotes brain
T841 1185-1195 NN denotes physiology
T842 1196-1199 CC denotes and
T843 1200-1210 VB denotes responding
T844 1211-1213 TO denotes to
T845 1214-1220 NN denotes injury
T846 1221-1223 CC denotes or
T847 1224-1231 NN denotes disease
T848 1233-1235 IN denotes In
T849 1236-1240 NN denotes fact
T850 1240-1241 -COMMA- denotes ,
T851 1242-1245 PDT denotes all
T852 1246-1249 DT denotes the
T853 1250-1264 JJ denotes aforementioned
T854 1265-1272 NN denotes studies
T855 1273-1276 VB denotes are
T856 1277-1286 VB denotes performed
T857 1287-1289 FW denotes in
T858 1290-1294 FW denotes vivo
T859 1296-1302 JJ denotes Little
T860 1303-1305 VB denotes is
T861 1306-1311 VB denotes known
T862 1312-1317 IN denotes about
T863 1318-1321 DT denotes the
T864 1322-1334 NN denotes relationship
T865 1335-1342 IN denotes between
T866 1343-1347 NN denotes Nrf2
T867 1348-1351 CC denotes and
T868 1352-1364 NN denotes inflammation
T869 1365-1367 IN denotes in
T870 1368-1378 NN denotes astrocytes
T871 1379-1384 IN denotes after
T872 1385-1388 NN denotes TBI
T873 1390-1399 RB denotes Therefore
T874 1399-1400 -COMMA- denotes ,
T875 1401-1405 RB denotes here
T876 1406-1408 PRP denotes we
T877 1409-1417 VB denotes analysed
T878 1418-1421 DT denotes the
T879 1422-1431 NN denotes influence
T880 1432-1434 IN denotes of
T881 1435-1439 NN denotes Nrf2
T882 1440-1442 IN denotes on
T883 1443-1446 DT denotes the
T884 1447-1457 NN denotes expression
T885 1458-1460 IN denotes of
T886 1461-1476 JJ denotes proinflammatory
T887 1477-1486 NN denotes cytokines
T888 1487-1489 IN denotes in
T889 1490-1497 JJ denotes primary
T890 1498-1506 VB denotes cultured
T891 1507-1517 NN denotes astrocytes
T892 1518-1522 IN denotes from
T893 1523-1533 JJ denotes transgenic
T894 1534-1538 NN denotes mice
T895 1539-1544 IN denotes after
T896 1545-1552 NN denotes scratch
T897 1553-1559 NN denotes injury
T1240 1588-1591 CD denotes 2.1
T1241 1593-1600 JJ denotes Primary
T1242 1601-1608 NN denotes Culture
T1243 1609-1612 CC denotes and
T1244 1613-1627 NN denotes Identification
T1245 1628-1630 IN denotes of
T1246 1631-1636 NN denotes Mouse
T1247 1637-1647 NN denotes Astrocytes
T1248 1648-1652 NN denotes Nrf2
T1249 1653-1661 NN denotes knockout
T1250 1662-1665 NN denotes ICR
T1251 1666-1670 NN denotes mice
T1252 1671-1675 VB denotes were
T1253 1676-1682 RB denotes kindly
T1254 1683-1691 VB denotes provided
T1255 1692-1694 IN denotes by
T1256 1695-1698 NNP denotes Dr.
T1257 1699-1705 NNP denotes Thomas
T1258 1706-1708 NNP denotes W.
T1259 1709-1716 NNP denotes Kensler
T1260 1717-1718 -LRB- denotes (
T1261 1718-1723 NNP denotes Johns
T1262 1724-1731 NNP denotes Hopkins
T1263 1732-1742 NNP denotes University
T1264 1742-1743 -COMMA- denotes ,
T1265 1744-1753 NNP denotes Baltimore
T1266 1753-1754 -COMMA- denotes ,
T1267 1755-1757 NNP denotes MD
T1268 1757-1758 -COMMA- denotes ,
T1269 1759-1762 NNP denotes USA
T1270 1762-1763 -RRB- denotes )
T1271 1765-1772 JJ denotes Primary
T1272 1773-1783 NN denotes astrocytes
T1273 1784-1788 VB denotes were
T1274 1789-1797 VB denotes obtained
T1275 1798-1802 IN denotes from
T1276 1803-1812 JJ denotes postnatal
T1277 1813-1822 JJ denotes 2-day-old
T1278 1823-1827 NN denotes Nrf2
T1279 1828-1832 JJ denotes wide
T1280 1833-1837 NN denotes type
T1281 1838-1839 -LRB- denotes (
T1282 1839-1841 NN denotes WT
T1283 1841-1842 -RRB- denotes )
T1284 1843-1846 CC denotes and
T1285 1847-1855 NN denotes knockout
T1286 1856-1857 -LRB- denotes (
T1287 1857-1859 NN denotes KO
T1288 1859-1860 -RRB- denotes )
T1289 1861-1865 NN denotes mice
T1290 1866-1867 -LRB- denotes (
T1291 1867-1868 CD denotes 6
T1292 1869-1873 NN denotes mice
T1293 1874-1877 IN denotes for
T1294 1878-1882 DT denotes each
T1295 1883-1891 NN denotes genotype
T1296 1891-1892 -RRB- denotes )
T1297 1894-1903 VB denotes Following
T1298 1904-1916 NN denotes decapitation
T1299 1916-1917 -COMMA- denotes ,
T1300 1918-1921 DT denotes the
T1301 1922-1930 NN denotes cortices
T1302 1931-1935 VB denotes were
T1303 1936-1945 VB denotes dissected
T1304 1946-1949 RP denotes out
T1305 1949-1950 -COMMA- denotes ,
T1306 1951-1954 CC denotes and
T1307 1955-1958 DT denotes the
T1308 1959-1967 NN denotes meninges
T1309 1968-1971 CC denotes and
T1310 1972-1982 VB denotes associated
T1311 1983-1988 NN denotes blood
T1312 1989-1996 NN denotes vessels
T1313 1997-2001 VB denotes were
T1314 2002-2009 VB denotes removed
T1315 2011-2014 DT denotes The
T1316 2015-2021 NN denotes tissue
T1317 2022-2025 VB denotes was
T1318 2026-2033 RB denotes roughly
T1319 2034-2041 VB denotes chopped
T1320 2042-2046 IN denotes with
T1321 2047-2048 DT denotes a
T1322 2049-2056 NN denotes scalpel
T1323 2057-2062 NN denotes blade
T1324 2062-2063 -COMMA- denotes ,
T1325 2064-2073 VB denotes incubated
T1326 2074-2076 IN denotes in
T1327 2077-2080 CD denotes 0.5
T1328 2080-2081 NN denotes %
T1329 2082-2089 NN denotes trypsin
T1330 2090-2093 IN denotes for
T1331 2094-2096 CD denotes 10
T1332 2097-2104 NN denotes minutes
T1333 2105-2107 IN denotes at
T1334 2108-2112 NN denotes 37°C
T1335 2112-2113 -COMMA- denotes ,
T1336 2114-2117 CC denotes and
T1337 2118-2126 VB denotes agitated
T1338 2127-2132 DT denotes every
T1339 2133-2136 JJ denotes few
T1340 2137-2144 NN denotes minutes
T1341 2146-2151 IN denotes After
T1342 2152-2161 NN denotes digestion
T1343 2161-2162 -COMMA- denotes ,
T1344 2163-2166 DT denotes the
T1345 2167-2173 NN denotes tissue
T1346 2174-2177 VB denotes was
T1347 2178-2184 VB denotes rinsed
T1348 2185-2190 RB denotes twice
T1349 2191-2193 IN denotes in
T1350 2194-2198 NN denotes DMEM
T1351 2199-2203 IN denotes with
T1352 2204-2206 CD denotes 10
T1353 2206-2207 NN denotes %
T1354 2208-2211 NNP denotes FBS
T1355 2211-2212 -COMMA- denotes ,
T1356 2213-2221 VB denotes followed
T1357 2222-2224 IN denotes by
T1358 2225-2226 DT denotes a
T1359 2227-2237 JJ denotes mechanical
T1360 2238-2250 NN denotes dissociation
T1361 2251-2253 IN denotes in
T1362 2254-2258 NN denotes DMEM
T1363 2259-2263 IN denotes with
T1364 2264-2266 CD denotes 20
T1365 2266-2267 NN denotes %
T1366 2268-2271 NN denotes FBS
T1367 2272-2275 CC denotes and
T1368 2276-2277 CD denotes 5
T1369 2278-2286 NN denotes units/mL
T1370 2287-2297 NN denotes penicillin
T1371 2297-2298 -COMMA- denotes ,
T1372 2299-2300 CD denotes 5
T1373 2301-2306 NN denotes μg/mL
T1374 2307-2319 NN denotes streptomycin
T1375 2320-2321 -LRB- denotes (
T1376 2321-2329 JJ denotes complete
T1377 2330-2337 NN denotes culture
T1378 2338-2344 NN denotes medium
T1379 2344-2345 -RRB- denotes )
T1380 2347-2352 IN denotes After
T1381 2353-2363 NN denotes incubation
T1382 2364-2367 IN denotes for
T1383 2368-2369 CD denotes 1
T1384 2370-2371 NN denotes h
T1385 2371-2372 -COMMA- denotes ,
T1386 2373-2376 DT denotes the
T1387 2377-2388 NN denotes supernatant
T1388 2389-2392 VB denotes was
T1389 2393-2404 VB denotes transferred
T1390 2405-2407 TO denotes to
T1391 2408-2409 DT denotes a
T1392 2410-2413 JJ denotes new
T1393 2414-2419 NN denotes flask
T1394 2420-2422 CC denotes or
T1395 2423-2427 JJ denotes dish
T1396 2428-2429 -LRB- denotes (
T1397 2429-2435 NNP denotes Costar
T1398 2435-2436 -COMMA- denotes ,
T1399 2437-2440 NNP denotes USA
T1400 2440-2441 -RRB- denotes )
T1401 2442-2445 IN denotes for
T1402 2446-2455 VB denotes depleting
T1403 2456-2459 DT denotes the
T1404 2460-2468 JJ denotes residual
T1405 2469-2479 JJ denotes epithelial
T1406 2480-2485 NN denotes cells
T1407 2487-2491 RB denotes Then
T1408 2492-2495 DT denotes the
T1409 2496-2501 NN denotes cells
T1410 2502-2506 VB denotes were
T1411 2507-2517 VB denotes cultivated
T1412 2518-2520 IN denotes at
T1413 2521-2525 NN denotes 37°C
T1414 2526-2530 IN denotes with
T1415 2531-2532 CD denotes 5
T1416 2532-2533 NN denotes %
T1417 2534-2537 NN denotes CO2
T1418 2539-2542 CC denotes And
T1419 2543-2546 DT denotes the
T1420 2547-2555 JJ denotes complete
T1421 2556-2563 NN denotes culture
T1422 2564-2570 NN denotes medium
T1423 2571-2574 VB denotes was
T1424 2575-2587 JJ denotes half-changed
T1425 2588-2593 RB denotes twice
T1426 2594-2595 DT denotes a
T1427 2596-2600 NN denotes week
T1428 2602-2612 NN denotes Astrocytes
T1429 2613-2621 VB denotes expanded
T1430 2622-2625 IN denotes for
T1431 2626-2631 IN denotes about
T1432 2632-2633 CD denotes 7
T1433 2634-2638 NN denotes days
T1434 2639-2641 TO denotes to
T1435 2642-2647 VB denotes reach
T1436 2648-2658 NN denotes confluence
T1437 2660-2664 RB denotes Then
T1438 2665-2668 DT denotes the
T1439 2669-2675 NN denotes flasks
T1440 2676-2678 CC denotes or
T1441 2679-2685 NN denotes dishes
T1442 2686-2690 VB denotes were
T1443 2691-2697 VB denotes shaken
T1444 2698-2700 IN denotes at
T1445 2701-2704 CD denotes 150
T1446 2705-2708 NN denotes rpm
T1447 2709-2712 IN denotes for
T1448 2713-2714 CD denotes 4
T1449 2715-2716 NN denotes h
T1450 2717-2719 TO denotes to
T1451 2720-2727 VB denotes deplete
T1452 2728-2731 DT denotes the
T1453 2732-2741 NN denotes microglia
T1454 2742-2745 CC denotes and
T1455 2746-2750 RB denotes less
T1456 2751-2759 JJ denotes adherent
T1457 2760-2765 NN denotes cells
T1458 2766-2770 IN denotes from
T1459 2771-2774 DT denotes the
T1460 2775-2783 NN denotes cultures
T1461 2785-2790 IN denotes After
T1462 2791-2798 VB denotes shaking
T1463 2798-2799 -COMMA- denotes ,
T1464 2800-2803 DT denotes the
T1465 2804-2813 VB denotes resulting
T1466 2814-2822 NN denotes cultures
T1467 2823-2827 VB denotes were
T1468 2828-2834 RB denotes mainly
T1469 2835-2845 NN denotes astrocytes
T1470 2845-2846 -COMMA- denotes ,
T1471 2847-2852 WDT denotes which
T1472 2853-2857 VB denotes were
T1473 2858-2868 VB denotes determined
T1474 2869-2871 IN denotes by
T1475 2872-2888 NN denotes immunoreactivity
T1476 2889-2892 IN denotes for
T1477 2893-2897 NN denotes GFAP
T1478 2898-2899 -LRB- denotes (
T1479 2899-2908 NN denotes sc-166481
T1480 2908-2909 -COMMA- denotes ,
T1481 2910-2915 NNP denotes Santa
T1482 2916-2920 NNP denotes Cruz
T1483 2921-2934 NNP denotes Biotechnology
T1484 2934-2935 -COMMA- denotes ,
T1485 2936-2938 NNP denotes CA
T1486 2938-2939 -COMMA- denotes ,
T1487 2940-2943 NNP denotes USA
T1488 2943-2944 -RRB- denotes )
T1489 2946-2951 NN denotes Cells
T1490 2952-2960 VB denotes passaged
T1491 2961-2964 IN denotes for
T1492 2965-2968 CD denotes 2-3
T1493 2969-2980 NN denotes generations
T1494 2981-2985 VB denotes were
T1495 2986-2990 VB denotes used
T1496 2991-2993 IN denotes in
T1497 2994-2997 DT denotes the
T1498 2998-3007 VB denotes following
T1499 3008-3015 NN denotes studies
T1821 3018-3021 CD denotes 2.2
T1822 3023-3025 IN denotes In
T1823 3026-3031 NNP denotes Vitro
T1824 3032-3037 NNP denotes Model
T1825 3038-3040 IN denotes of
T1826 3041-3044 NNP denotes TBI
T1827 3045-3056 VB denotes Established
T1828 3057-3059 IN denotes by
T1829 3060-3067 NNP denotes Scratch
T1830 3068-3074 NNP denotes Injury
T1831 3075-3084 NN denotes Astrocyte
T1832 3085-3092 NN denotes scratch
T1833 3093-3099 NN denotes injury
T1834 3100-3103 VB denotes was
T1835 3104-3113 VB denotes performed
T1836 3114-3116 IN denotes as
T1837 3117-3119 IN denotes in
T1838 3120-3121 DT denotes a
T1839 3122-3130 JJ denotes previous
T1840 3131-3137 NN denotes report
T1841 3138-3139 -LRB- denotes [
T1842 3139-3140 CD denotes 7
T1843 3140-3141 -RRB- denotes ]
T1844 3143-3153 NN denotes Astrocytes
T1845 3154-3158 VB denotes were
T1846 3159-3166 VB denotes planted
T1847 3167-3169 IN denotes in
T1848 3170-3176 JJ denotes 6-well
T1849 3177-3183 NN denotes plates
T1850 3184-3187 CC denotes and
T1851 3188-3193 VB denotes grown
T1852 3194-3196 TO denotes to
T1853 3197-3207 VB denotes confluence
T1854 3209-3212 DT denotes The
T1855 3213-3217 NN denotes cell
T1856 3218-3227 NN denotes monolayer
T1857 3228-3231 VB denotes was
T1858 3232-3241 VB denotes scratched
T1859 3242-3246 IN denotes with
T1860 3247-3248 DT denotes a
T1861 3249-3256 JJ denotes sterile
T1862 3257-3260 NN denotes 26G
T1863 3261-3268 NN denotes syringe
T1864 3269-3275 NN denotes needle
T1865 3275-3276 -COMMA- denotes ,
T1866 3277-3286 VB denotes resulting
T1867 3287-3289 IN denotes in
T1868 3290-3293 DT denotes the
T1869 3294-3303 NN denotes formation
T1870 3304-3306 IN denotes of
T1871 3307-3308 DT denotes a
T1872 3309-3312 CD denotes 0.5
T1873 3313-3315 NN denotes mm
T1874 3316-3320 JJ denotes wide
T1875 3321-3324 NN denotes gap
T1876 3326-3337 RB denotes Immediately
T1877 3338-3343 IN denotes after
T1878 3344-3351 NN denotes scratch
T1879 3351-3352 -COMMA- denotes ,
T1880 3353-3358 NN denotes cells
T1881 3359-3363 VB denotes were
T1882 3364-3370 VB denotes washed
T1883 3371-3376 RB denotes twice
T1884 3377-3381 IN denotes with
T1885 3382-3389 JJ denotes sterile
T1886 3390-3393 NNP denotes PBS
T1887 3393-3394 -COMMA- denotes ,
T1888 3395-3403 VB denotes cultured
T1889 3404-3408 IN denotes with
T1890 3409-3417 JJ denotes complete
T1891 3418-3425 NN denotes culture
T1892 3426-3432 NN denotes medium
T1893 3432-3433 -COMMA- denotes ,
T1894 3434-3437 CC denotes and
T1895 3438-3443 VB denotes named
T1896 3444-3446 IN denotes as
T1897 3447-3450 NN denotes TBI
T1898 3451-3456 NN denotes group
T1899 3458-3463 NN denotes Cells
T1900 3463-3464 -COMMA- denotes ,
T1901 3465-3470 WDT denotes which
T1902 3471-3474 VB denotes did
T1903 3475-3478 RB denotes not
T1904 3479-3487 VB denotes received
T1905 3488-3495 NN denotes scratch
T1906 3495-3496 -COMMA- denotes ,
T1907 3497-3501 VB denotes were
T1908 3502-3506 VB denotes used
T1909 3507-3509 IN denotes as
T1910 3510-3515 JJ denotes blank
T1911 3516-3523 NN denotes control
T1912 3524-3527 CC denotes and
T1913 3528-3533 VB denotes named
T1914 3534-3536 IN denotes as
T1915 3537-3541 NN denotes sham
T1916 3542-3547 NN denotes group
T2047 3550-3553 CD denotes 2.3
T2048 3555-3559 NNP denotes Cell
T2049 3560-3565 NNP denotes Death
T2050 3566-3577 NNP denotes Measurement
T2051 3578-3580 IN denotes by
T2052 3581-3586 NN denotes CCK-8
T2053 3587-3592 NN denotes Assay
T2054 3593-3594 CD denotes 1
T2055 3595-3596 SYM denotes ×
T2056 3597-3605 NN denotes 103/well
T2057 3606-3611 NN denotes cells
T2058 3612-3616 VB denotes were
T2059 3617-3623 VB denotes seeded
T2060 3624-3626 TO denotes to
T2061 3627-3634 JJ denotes 96-well
T2062 3635-3642 NN denotes culture
T2063 3643-3649 NN denotes plates
T2064 3650-3653 CC denotes and
T2065 3654-3664 VB denotes cultivated
T2066 3665-3668 IN denotes for
T2067 3669-3671 CD denotes 24
T2068 3672-3673 NN denotes h
T2069 3674-3676 TO denotes to
T2070 3677-3683 VB denotes adhere
T2071 3685-3689 RB denotes Then
T2072 3690-3693 DT denotes the
T2073 3694-3698 NN denotes cell
T2074 3699-3702 VB denotes was
T2075 3703-3710 VB denotes scrated
T2076 3711-3713 IN denotes as
T2077 3714-3723 VB denotes mentioned
T2078 3724-3729 IN denotes above
T2079 3731-3740 NN denotes Astrocyte
T2080 3741-3745 NN denotes cell
T2081 3746-3751 NN denotes death
T2082 3752-3755 VB denotes was
T2083 3756-3764 VB denotes assessed
T2084 3765-3767 IN denotes by
T2085 3768-3772 NN denotes cell
T2086 3773-3781 NN denotes counting
T2087 3782-3787 NN denotes kit-8
T2088 3788-3789 -LRB- denotes (
T2089 3789-3794 NN denotes CCK-8
T2090 3794-3795 -RRB- denotes )
T2091 3796-3797 -LRB- denotes (
T2092 3797-3804 NNP denotes Dojindo
T2093 3804-3805 -COMMA- denotes ,
T2094 3806-3811 NNP denotes Japan
T2095 3811-3812 -RRB- denotes )
T2096 3813-3818 NN denotes assay
T2097 3819-3821 CD denotes 24
T2098 3822-3823 NN denotes h
T2099 3824-3829 IN denotes after
T2100 3830-3837 NN denotes scratch
T2101 3838-3847 VB denotes according
T2102 3848-3850 TO denotes to
T2103 3851-3854 DT denotes the
T2104 3855-3867 NN denotes manufacturer
T2105 3867-3869 POS denotes 's
T2106 3870-3878 NN denotes protocol
T2107 3880-3887 NNP denotes Briefly
T2108 3887-3888 -COMMA- denotes ,
T2109 3889-3891 CD denotes 10
T2110 3892-3894 NN denotes μL
T2111 3895-3900 NN denotes CCK-8
T2112 3901-3904 VB denotes was
T2113 3905-3910 VB denotes added
T2114 3911-3915 IN denotes into
T2115 3916-3921 DT denotes every
T2116 3922-3926 RB denotes well
T2117 3927-3930 CC denotes and
T2118 3931-3940 VB denotes incubated
T2119 3941-3944 IN denotes for
T2120 3945-3946 CD denotes 1
T2121 3947-3948 NN denotes h
T2122 3950-3954 RB denotes Then
T2123 3955-3957 NN denotes OD
T2124 3958-3963 NN denotes value
T2125 3964-3967 VB denotes was
T2126 3968-3972 VB denotes read
T2127 3973-3975 IN denotes at
T2128 3976-3979 CD denotes 450
T2129 3980-3982 NN denotes nm
T2130 3983-3988 VB denotes using
T2131 3989-3990 DT denotes a
T2132 3991-3998 JJ denotes Bio-Rad
T2133 3999-4004 NN denotes ELISA
T2134 4005-4015 NN denotes microplate
T2135 4016-4022 NN denotes reader
T2136 4023-4024 -LRB- denotes (
T2137 4024-4031 NNP denotes Bio-Rad
T2138 4032-4044 NNP denotes Laboratories
T2139 4044-4045 -COMMA- denotes ,
T2140 4046-4048 NNP denotes CA
T2141 4048-4049 -COMMA- denotes ,
T2142 4050-4053 NNP denotes USA
T2143 4053-4054 -RRB- denotes )
T2144 4056-4059 DT denotes All
T2145 4060-4072 NN denotes measurements
T2146 4073-4077 VB denotes were
T2147 4078-4087 VB denotes performed
T2148 4088-4090 IN denotes in
T2149 4091-4103 NN denotes sextuplicate
T2150 4105-4112 NN denotes Results
T2151 4113-4117 VB denotes were
T2152 4118-4127 VB denotes expressed
T2153 4128-4130 IN denotes as
T2154 4131-4135 NN denotes mean
T2155 4136-4138 IN denotes of
T2156 4139-4141 NN denotes OD
T2157 4142-4147 NN denotes value
T2158 4148-4150 IN denotes at
T2159 4151-4154 CD denotes 450
T2160 4155-4157 NN denotes nm
T2161 4158-4159 SYM denotes ±
T2162 4160-4162 NN denotes SD
T2323 4165-4168 CD denotes 2.4
T2324 4170-4185 JJ denotes Electrophoretic
T2325 4186-4194 NN denotes Mobility
T2326 4195-4200 NN denotes Shift
T2327 4201-4206 NN denotes Assay
T2328 4207-4208 -LRB- denotes (
T2329 4208-4212 NN denotes EMSA
T2330 4212-4213 -RRB- denotes )
T2331 4214-4224 NN denotes Monolayers
T2332 4225-4227 IN denotes of
T2333 4228-4238 NN denotes astrocytes
T2334 4239-4243 VB denotes were
T2335 4244-4250 VB denotes washed
T2336 4251-4255 IN denotes with
T2337 4256-4259 NNP denotes PBS
T2338 4260-4263 CC denotes and
T2339 4264-4273 VB denotes harvested
T2340 4274-4276 IN denotes by
T2341 4277-4285 VB denotes scraping
T2342 4286-4290 IN denotes into
T2343 4291-4295 JJ denotes cold
T2344 4296-4299 NNP denotes PBS
T2345 4301-4304 DT denotes The
T2346 4305-4309 NN denotes cell
T2347 4310-4316 NN denotes pellet
T2348 4317-4325 VB denotes obtained
T2349 4326-4328 IN denotes by
T2350 4329-4343 NN denotes centrifugation
T2351 4344-4347 VB denotes was
T2352 4348-4359 VB denotes resuspended
T2353 4360-4362 IN denotes in
T2354 4363-4369 NN denotes buffer
T2355 4370-4380 VB denotes containing
T2356 4381-4383 CD denotes 10
T2357 4384-4386 NN denotes mM
T2358 4387-4392 NN denotes HEPES
T2359 4393-4394 -LRB- denotes (
T2360 4394-4396 NN denotes pH
T2361 4397-4400 CD denotes 7.9
T2362 4400-4401 -RRB- denotes )
T2363 4401-4402 -COMMA- denotes ,
T2364 4403-4405 CD denotes 10
T2365 4406-4408 NN denotes mM
T2366 4409-4412 NN denotes KCl
T2367 4412-4413 -COMMA- denotes ,
T2368 4414-4417 CD denotes 0.1
T2369 4418-4420 NN denotes mM
T2370 4421-4425 NN denotes EDTA
T2371 4425-4426 -COMMA- denotes ,
T2372 4427-4430 CD denotes 0.1
T2373 4431-4433 NN denotes mM
T2374 4434-4438 NN denotes EGTA
T2375 4438-4439 -COMMA- denotes ,
T2376 4440-4443 CD denotes 1.0
T2377 4444-4446 NN denotes mM
T2378 4447-4450 NN denotes DTT
T2379 4450-4451 -COMMA- denotes ,
T2380 4452-4455 CC denotes and
T2381 4456-4459 CD denotes 0.5
T2382 4460-4462 NN denotes mM
T2383 4463-4483 NN denotes phenylmethylsulfonyl
T2384 4484-4492 NN denotes fluoride
T2385 4494-4498 RB denotes Then
T2386 4499-4501 CD denotes 10
T2387 4501-4502 NN denotes %
T2388 4503-4510 NN denotes Nonidet
T2389 4511-4515 NN denotes P-40
T2390 4516-4519 VB denotes was
T2391 4520-4525 VB denotes added
T2392 4526-4529 CC denotes and
T2393 4530-4538 VB denotes vortexed
T2394 4539-4546 NN denotes briefly
T2395 4546-4547 -COMMA- denotes ,
T2396 4548-4551 CC denotes and
T2397 4552-4555 DT denotes the
T2398 4556-4562 NN denotes nuclei
T2399 4563-4567 VB denotes were
T2400 4568-4576 VB denotes pelleted
T2401 4577-4579 IN denotes by
T2402 4580-4594 NN denotes centrifugation
T2403 4596-4599 DT denotes The
T2404 4600-4607 JJ denotes nuclear
T2405 4608-4616 NN denotes proteins
T2406 4617-4621 VB denotes were
T2407 4622-4631 VB denotes extracted
T2408 4632-4636 IN denotes with
T2409 4637-4643 NN denotes buffer
T2410 4644-4654 VB denotes containing
T2411 4655-4657 CD denotes 20
T2412 4658-4660 NN denotes mM
T2413 4661-4666 NN denotes HEPES
T2414 4667-4668 -LRB- denotes (
T2415 4668-4670 NN denotes pH
T2416 4671-4674 CD denotes 7.9
T2417 4674-4675 -RRB- denotes )
T2418 4675-4676 -COMMA- denotes ,
T2419 4677-4680 CD denotes 0.4
T2420 4681-4683 NN denotes mM
T2421 4684-4688 NN denotes NaCl
T2422 4688-4689 -COMMA- denotes ,
T2423 4690-4693 CD denotes 1.0
T2424 4694-4696 NN denotes mM
T2425 4697-4701 NN denotes EDTA
T2426 4701-4702 -COMMA- denotes ,
T2427 4703-4706 CD denotes 1.0
T2428 4707-4709 NN denotes mM
T2429 4710-4714 NN denotes EGTA
T2430 4714-4715 -COMMA- denotes ,
T2431 4716-4719 CD denotes 1.0
T2432 4720-4722 NN denotes mM
T2433 4723-4726 NN denotes DTT
T2434 4726-4727 -COMMA- denotes ,
T2435 4728-4731 CC denotes and
T2436 4732-4735 CD denotes 1.0
T2437 4736-4738 NN denotes mM
T2438 4739-4759 NN denotes phenylmethylsulfonyl
T2439 4760-4768 NN denotes fluoride
T2440 4770-4779 JJ denotes Insoluble
T2441 4780-4788 NN denotes material
T2442 4789-4792 VB denotes was
T2443 4793-4800 VB denotes removed
T2444 4801-4803 IN denotes by
T2445 4804-4818 NN denotes centrifugation
T2446 4819-4821 IN denotes at
T2447 4822-4827 CD denotes 14000
T2448 4828-4831 NN denotes rpm
T2449 4831-4832 -COMMA- denotes ,
T2450 4833-4836 CC denotes and
T2451 4837-4840 DT denotes the
T2452 4841-4852 NN denotes supernatant
T2453 4853-4863 VB denotes containing
T2454 4864-4867 DT denotes the
T2455 4868-4875 JJ denotes nuclear
T2456 4876-4884 NN denotes proteins
T2457 4885-4888 VB denotes was
T2458 4889-4895 VB denotes stored
T2459 4896-4898 IN denotes at
T2460 4899-4904 NN denotes –80°C
T2461 4905-4910 IN denotes until
T2462 4911-4914 NN denotes use
T2463 4916-4923 NN denotes Protein
T2464 4924-4937 NN denotes concentration
T2465 4938-4941 VB denotes was
T2466 4942-4952 VB denotes determined
T2467 4953-4958 VB denotes using
T2468 4959-4960 DT denotes a
T2469 4961-4974 JJ denotes bicinchoninic
T2470 4975-4979 NN denotes acid
T2471 4980-4985 NN denotes assay
T2472 4986-4989 NN denotes kit
T2473 4990-4994 IN denotes with
T2474 4995-5001 JJ denotes bovine
T2475 5002-5007 NN denotes serum
T2476 5008-5015 NN denotes albumin
T2477 5016-5018 IN denotes as
T2478 5019-5022 DT denotes the
T2479 5023-5031 JJ denotes standard
T2480 5032-5033 -LRB- denotes (
T2481 5033-5039 NNP denotes Pierce
T2482 5040-5052 NNP denotes Biochemicals
T2483 5052-5053 -COMMA- denotes ,
T2484 5054-5062 NNP denotes Rockford
T2485 5062-5063 -COMMA- denotes ,
T2486 5064-5066 NNP denotes IL
T2487 5066-5067 -COMMA- denotes ,
T2488 5068-5071 NNP denotes USA
T2489 5071-5072 -RRB- denotes )
T2490 5074-5078 NN denotes EMSA
T2491 5079-5082 VB denotes was
T2492 5083-5092 VB denotes performed
T2493 5093-5098 VB denotes using
T2494 5099-5102 NN denotes gel
T2495 5103-5108 NN denotes shift
T2496 5109-5114 NN denotes assay
T2497 5115-5121 NN denotes system
T2498 5122-5123 -LRB- denotes (
T2499 5123-5130 NNP denotes Promega
T2500 5130-5131 -COMMA- denotes ,
T2501 5132-5139 NNP denotes Madison
T2502 5139-5140 -COMMA- denotes ,
T2503 5141-5143 NNP denotes WI
T2504 5143-5144 -COMMA- denotes ,
T2505 5145-5148 NNP denotes USA
T2506 5148-5149 -RRB- denotes )
T2507 5151-5160 NNP denotes Consensus
T2508 5161-5176 NN denotes oligonucleotide
T2509 5177-5182 NN denotes probe
T2510 5183-5184 -LRB- denotes (
T2511 5184-5211 NN denotes 5′-AGTTGAGGGGACTTTCCCAGGG-3
T2512 5211-5212 -DQE- denotes ′
T2513 5212-5213 -RRB- denotes )
T2514 5214-5217 VB denotes was
T2515 5218-5229 VB denotes end-labeled
T2516 5230-5232 IN denotes by
T2517 5233-5250 NN denotes T4-polynucleotide
T2518 5251-5257 NN denotes kinase
T2519 5258-5263 VB denotes using
T2520 5264-5265 -LRB- denotes [
T2521 5265-5270 NN denotes γ-32P
T2522 5270-5271 -RRB- denotes ]
T2523 5271-5275 NN denotes -ATP
T2524 5276-5277 -LRB- denotes (
T2525 5277-5281 NNP denotes Free
T2526 5282-5290 NNP denotes Biotech.
T2527 5290-5291 -COMMA- denotes ,
T2528 5292-5299 NNP denotes Beijing
T2529 5299-5300 -COMMA- denotes ,
T2530 5301-5306 NNP denotes China
T2531 5306-5307 -RRB- denotes )
T2532 5309-5316 JJ denotes Nuclear
T2533 5317-5324 NN denotes protein
T2534 5325-5326 -LRB- denotes (
T2535 5326-5328 CD denotes 20
T2536 5329-5331 NN denotes μg
T2537 5331-5332 -RRB- denotes )
T2538 5333-5336 VB denotes was
T2539 5337-5349 VB denotes preincubated
T2540 5350-5352 IN denotes in
T2541 5353-5355 CD denotes 20
T2542 5356-5358 NN denotes μL
T2543 5359-5366 NN denotes binding
T2544 5367-5373 NN denotes buffer
T2545 5374-5384 VB denotes containing
T2546 5385-5387 CD denotes 10
T2547 5388-5390 NN denotes mM
T2548 5391-5399 NN denotes Tris-HCl
T2549 5400-5401 -LRB- denotes (
T2550 5401-5403 NN denotes PH
T2551 5404-5407 CD denotes 7.5
T2552 5407-5408 -RRB- denotes )
T2553 5408-5409 -COMMA- denotes ,
T2554 5410-5411 CD denotes 1
T2555 5412-5414 NN denotes mM
T2556 5415-5420 NN denotes MgCl2
T2557 5420-5421 -COMMA- denotes ,
T2558 5422-5425 CD denotes 0.5
T2559 5426-5428 NN denotes mM
T2560 5429-5433 NN denotes NaCl
T2561 5433-5434 -COMMA- denotes ,
T2562 5435-5436 CD denotes 4
T2563 5436-5437 NN denotes %
T2564 5438-5446 NN denotes glycerol
T2565 5446-5447 -COMMA- denotes ,
T2566 5448-5451 CD denotes 0.5
T2567 5452-5454 NN denotes mM
T2568 5455-5459 NN denotes EDTA
T2569 5459-5460 -COMMA- denotes ,
T2570 5461-5464 CD denotes 0.5
T2571 5465-5467 NN denotes mM
T2572 5468-5471 NN denotes DTT
T2573 5471-5472 -COMMA- denotes ,
T2574 5473-5476 CC denotes and
T2575 5477-5478 CD denotes 2
T2576 5479-5481 NN denotes μg
T2577 5482-5486 NN denotes poly
T2578 5487-5492 NN denotes dI-dC
T2579 5493-5496 IN denotes for
T2580 5497-5499 CD denotes 20
T2581 5500-5507 NN denotes minutes
T2582 5508-5510 IN denotes on
T2583 5511-5514 NN denotes ice
T2584 5516-5521 IN denotes After
T2585 5522-5530 NN denotes addition
T2586 5531-5533 IN denotes of
T2587 5534-5537 DT denotes the
T2588 5538-5539 CD denotes 1
T2589 5540-5542 NN denotes μL
T2590 5543-5553 JJ denotes 32P-labled
T2591 5554-5569 NN denotes oligonucleotide
T2592 5570-5575 NN denotes probe
T2593 5575-5576 -COMMA- denotes ,
T2594 5577-5580 DT denotes the
T2595 5581-5591 NN denotes incubation
T2596 5592-5595 VB denotes was
T2597 5596-5605 VB denotes continued
T2598 5606-5609 IN denotes for
T2599 5610-5612 CD denotes 20
T2600 5613-5620 NN denotes minutes
T2601 5621-5623 IN denotes on
T2602 5624-5627 NN denotes ice
T2603 5629-5632 DT denotes The
T2604 5633-5644 JJ denotes DNA-protein
T2605 5645-5654 NN denotes complexes
T2606 5655-5659 VB denotes were
T2607 5660-5669 VB denotes separated
T2608 5670-5672 IN denotes by
T2609 5673-5688 NN denotes electrophoresis
T2610 5689-5691 IN denotes on
T2611 5692-5693 CD denotes 4
T2612 5693-5694 NN denotes %
T2613 5695-5708 JJ denotes nondenaturing
T2614 5709-5723 NN denotes polyacrylamide
T2615 5724-5727 NN denotes gel
T2616 5728-5730 IN denotes in
T2617 5731-5734 CD denotes 0.5
T2618 5735-5736 SYM denotes ×
T2619 5737-5740 NN denotes TBE
T2620 5741-5747 NN denotes buffer
T2621 5748-5749 -LRB- denotes (
T2622 5749-5765 NN denotes tris-borate-EDTA
T2623 5765-5766 -RRB- denotes )
T2624 5767-5769 IN denotes at
T2625 5770-5773 CD denotes 390
T2626 5774-5775 NN denotes V
T2627 5776-5779 IN denotes for
T2628 5780-5781 CD denotes 1
T2629 5782-5786 NN denotes hour
T2630 5787-5789 IN denotes at
T2631 5790-5793 NN denotes 4°C
T2632 5795-5800 IN denotes After
T2633 5801-5816 NN denotes electrophoresis
T2634 5816-5817 -COMMA- denotes ,
T2635 5818-5821 DT denotes the
T2636 5822-5825 NN denotes gel
T2637 5826-5829 VB denotes was
T2638 5830-5835 VB denotes dried
T2639 5836-5839 CC denotes and
T2640 5840-5847 VB denotes exposed
T2641 5848-5850 TO denotes to
T2642 5851-5856 NN denotes X-ray
T2643 5857-5861 NN denotes film
T2644 5862-5863 -LRB- denotes (
T2645 5863-5867 NNP denotes Fuji
T2646 5868-5877 NNP denotes Hyperfilm
T2647 5877-5878 -COMMA- denotes ,
T2648 5879-5884 NNP denotes Tokyo
T2649 5884-5885 -COMMA- denotes ,
T2650 5886-5891 NNP denotes Japan
T2651 5891-5892 -RRB- denotes )
T2652 5894-5900 NN denotes Levels
T2653 5901-5903 IN denotes of
T2654 5904-5909 NN denotes NF-κB
T2655 5910-5913 NN denotes DNA
T2656 5914-5921 NN denotes binding
T2657 5922-5930 NN denotes activity
T2658 5931-5935 VB denotes were
T2659 5936-5946 VB denotes quantified
T2660 5947-5949 IN denotes by
T2661 5950-5958 NN denotes software
T2662 5959-5965 NN denotes ImageJ
T3115 5968-5971 CD denotes 2.5
T3116 5973-5979 NN denotes RT-PCR
T3117 5980-5985 JJ denotes Total
T3118 5986-5989 NN denotes RNA
T3119 5990-5993 VB denotes was
T3120 5994-6002 VB denotes isolated
T3121 6003-6007 IN denotes with
T3122 6008-6014 NN denotes Trizol
T3123 6015-6016 -LRB- denotes (
T3124 6016-6026 NN denotes Invitrogen
T3125 6026-6027 -COMMA- denotes ,
T3126 6028-6030 NNP denotes CA
T3127 6030-6031 -COMMA- denotes ,
T3128 6032-6035 NNP denotes USA
T3129 6035-6036 -RRB- denotes )
T3130 6036-6037 -COMMA- denotes ,
T3131 6038-6041 CC denotes and
T3132 6042-6057 JJ denotes single-stranded
T3133 6058-6062 NN denotes cDNA
T3134 6063-6066 VB denotes was
T3135 6067-6078 VB denotes synthesized
T3136 6079-6083 IN denotes from
T3137 6084-6085 CD denotes 2
T3138 6086-6088 NN denotes μg
T3139 6089-6091 IN denotes of
T3140 6092-6097 JJ denotes total
T3141 6098-6101 NN denotes RNA
T3142 6102-6106 IN denotes with
T3143 6107-6116 JJ denotes BU-Script
T3144 6117-6123 NN denotes RT-Kit
T3145 6124-6125 -LRB- denotes (
T3146 6125-6133 NNP denotes Biunique
T3147 6133-6134 -COMMA- denotes ,
T3148 6135-6142 NNP denotes Jiangsu
T3149 6142-6143 -COMMA- denotes ,
T3150 6144-6149 NNP denotes China
T3151 6149-6150 -RRB- denotes )
T3152 6151-6160 VB denotes according
T3153 6161-6163 TO denotes to
T3154 6164-6167 DT denotes the
T3155 6168-6180 NN denotes manufacturer
T3156 6180-6182 POS denotes 's
T3157 6183-6191 NN denotes protocol
T3158 6193-6196 DT denotes The
T3159 6197-6201 NN denotes cDNA
T3160 6202-6205 VB denotes was
T3161 6206-6212 VB denotes stored
T3162 6213-6215 IN denotes in
T3163 6216-6221 NN denotes −20°C
T3164 6223-6230 JJ denotes Reverse
T3165 6231-6244 NN denotes transcription
T3166 6245-6248 VB denotes was
T3167 6249-6258 VB denotes conducted
T3168 6259-6263 IN denotes with
T3169 6264-6269 NNP denotes GoTaq
T3170 6270-6275 NNP denotes Green
T3171 6276-6282 NNP denotes Master
T3172 6283-6286 NNP denotes Mix
T3173 6287-6288 -LRB- denotes (
T3174 6288-6295 NNP denotes Promega
T3175 6295-6296 -COMMA- denotes ,
T3176 6297-6299 NNP denotes WI
T3177 6299-6300 -COMMA- denotes ,
T3178 6301-6304 NNP denotes USA
T3179 6304-6305 -RRB- denotes )
T3180 6306-6315 VB denotes according
T3181 6316-6318 TO denotes to
T3182 6319-6322 DT denotes the
T3183 6323-6335 NN denotes manufacturer
T3184 6335-6337 POS denotes 's
T3185 6338-6346 NN denotes protocol
T3186 6349-6354 JJ denotes Table
T3187 6355-6356 CD denotes 1
T3188 6357-6362 VB denotes shows
T3189 6363-6366 DT denotes the
T3190 6367-6374 NN denotes primers
T3191 6375-6378 CC denotes and
T3192 6379-6382 NN denotes PCR
T3193 6383-6393 NN denotes parameters
T3194 6395-6398 NN denotes PCR
T3195 6399-6407 NN denotes products
T3196 6408-6412 VB denotes were
T3197 6413-6421 VB denotes detected
T3198 6422-6424 IN denotes by
T3199 6425-6432 NN denotes agarose
T3200 6433-6436 NN denotes gel
T3201 6437-6452 NN denotes electrophoresis
T3202 6454-6457 DT denotes The
T3203 6458-6467 NN denotes intensity
T3204 6468-6470 IN denotes of
T3205 6471-6474 DT denotes the
T3206 6475-6480 NN denotes bands
T3207 6481-6484 VB denotes was
T3208 6485-6493 VB denotes analyzed
T3209 6494-6496 IN denotes by
T3210 6497-6503 NN denotes ImageJ
T3211 6504-6511 NN denotes program
T3212 6513-6516 DT denotes The
T3213 6517-6522 NN denotes level
T3214 6523-6525 IN denotes of
T3215 6526-6533 NN denotes β-actin
T3216 6534-6537 VB denotes was
T3217 6538-6542 VB denotes used
T3218 6543-6545 IN denotes as
T3219 6546-6548 DT denotes an
T3220 6549-6557 JJ denotes internal
T3221 6558-6566 NN denotes standard
T3389 6569-6572 CD denotes 2.6
T3390 6574-6581 NNP denotes Western
T3391 6582-6586 NNP denotes Blot
T3392 6587-6589 TO denotes To
T3393 6590-6596 VB denotes obtain
T3394 6597-6602 JJ denotes total
T3395 6603-6610 NN denotes protein
T3396 6611-6618 NN denotes lysates
T3397 6618-6619 -COMMA- denotes ,
T3398 6620-6625 NN denotes cells
T3399 6626-6630 VB denotes were
T3400 6631-6642 VB denotes homogenized
T3401 6643-6645 IN denotes in
T3402 6646-6650 NN denotes RIPA
T3403 6651-6657 NN denotes buffer
T3404 6658-6659 -LRB- denotes (
T3405 6659-6660 CD denotes 1
T3406 6660-6661 NN denotes %
T3407 6662-6666 NN denotes NP40
T3408 6666-6667 -COMMA- denotes ,
T3409 6668-6671 CD denotes 0.5
T3410 6671-6672 NN denotes %
T3411 6673-6679 NN denotes sodium
T3412 6680-6692 NN denotes deoxycholate
T3413 6692-6693 -COMMA- denotes ,
T3414 6694-6697 CD denotes 0.1
T3415 6697-6698 NN denotes %
T3416 6699-6702 NN denotes SDS
T3417 6702-6703 -COMMA- denotes ,
T3418 6704-6705 CD denotes 1
T3419 6706-6708 NN denotes mM
T3420 6709-6713 NN denotes EDTA
T3421 6713-6714 -COMMA- denotes ,
T3422 6715-6716 CD denotes 1
T3423 6717-6719 NN denotes mM
T3424 6720-6724 NN denotes EGTA
T3425 6724-6725 -COMMA- denotes ,
T3426 6726-6727 CD denotes 1
T3427 6728-6730 NN denotes mM
T3428 6731-6737 NN denotes Na3VO4
T3429 6737-6738 -COMMA- denotes ,
T3430 6739-6741 CD denotes 20
T3431 6742-6744 NN denotes mM
T3432 6745-6748 NN denotes NaF
T3433 6748-6749 -COMMA- denotes ,
T3434 6750-6753 CD denotes 0.5
T3435 6754-6756 NN denotes mM
T3436 6757-6760 NN denotes DTT
T3437 6760-6761 -COMMA- denotes ,
T3438 6762-6763 CD denotes 1
T3439 6764-6766 NN denotes mM
T3440 6767-6771 NN denotes PMSF
T3441 6771-6772 -COMMA- denotes ,
T3442 6773-6776 CC denotes and
T3443 6777-6785 NN denotes protease
T3444 6786-6795 NN denotes inhibitor
T3445 6796-6804 NN denotes cocktail
T3446 6805-6807 IN denotes in
T3447 6808-6811 NNP denotes PBS
T3448 6812-6814 NN denotes pH
T3449 6815-6818 CD denotes 7.4
T3450 6818-6819 -RRB- denotes )
T3451 6820-6823 CC denotes and
T3452 6824-6835 VB denotes centrifuged
T3453 6836-6838 IN denotes at
T3454 6839-6845 CD denotes 12,000
T3455 6846-6847 NN denotes g
T3456 6848-6851 IN denotes for
T3457 6852-6854 CD denotes 15
T3458 6855-6858 NN denotes min
T3459 6859-6861 IN denotes at
T3460 6862-6865 NN denotes 4°C
T3461 6867-6874 NN denotes Protein
T3462 6875-6889 NN denotes concentrations
T3463 6890-6894 VB denotes were
T3464 6895-6904 VB denotes estimated
T3465 6905-6907 IN denotes by
T3466 6908-6917 NNP denotes Coomassie
T3467 6918-6922 NNP denotes Plus
T3468 6923-6930 NNP denotes Protein
T3469 6931-6936 NNP denotes Assay
T3470 6937-6944 NNP denotes Reagent
T3471 6945-6946 -LRB- denotes (
T3472 6946-6952 NNP denotes Pierce
T3473 6952-6953 -COMMA- denotes ,
T3474 6954-6956 NNP denotes IL
T3475 6956-6957 -COMMA- denotes ,
T3476 6958-6961 NNP denotes USA
T3477 6961-6962 -RRB- denotes )
T3478 6964-6969 CD denotes Fifty
T3479 6970-6980 NN denotes micrograms
T3480 6981-6983 IN denotes of
T3481 6984-6987 DT denotes the
T3482 6988-6997 VB denotes resulting
T3483 6998-7007 JJ denotes cytosolic
T3484 7008-7015 NN denotes protein
T3485 7016-7024 NN denotes extracts
T3486 7025-7029 VB denotes were
T3487 7030-7044 JJ denotes heat-denatured
T3488 7045-7047 IN denotes in
T3489 7048-7055 NNP denotes Laemmli
T3490 7056-7062 NN denotes sample
T3491 7063-7070 NN denotes loading
T3492 7071-7077 NN denotes buffer
T3493 7077-7078 -COMMA- denotes ,
T3494 7079-7088 VB denotes separated
T3495 7089-7091 IN denotes by
T3496 7092-7094 CD denotes 10
T3497 7094-7095 NN denotes %
T3498 7096-7102 NN denotes sodium
T3499 7103-7110 NN denotes dodecyl
T3500 7111-7118 NN denotes sulfate
T3501 7119-7133 NN denotes polyacrylamide
T3502 7134-7137 NN denotes gel
T3503 7138-7153 NN denotes electrophoresis
T3504 7153-7154 -COMMA- denotes ,
T3505 7155-7158 CC denotes and
T3506 7159-7173 VB denotes electroblotted
T3507 7174-7178 IN denotes onto
T3508 7179-7180 DT denotes a
T3509 7181-7195 NN denotes nitrocellulose
T3510 7196-7204 NN denotes membrane
T3511 7206-7209 IN denotes For
T3512 7210-7224 NN denotes immunoblotting
T3513 7224-7225 -COMMA- denotes ,
T3514 7226-7235 NN denotes membranes
T3515 7236-7240 VB denotes were
T3516 7241-7248 VB denotes blocked
T3517 7249-7253 IN denotes with
T3518 7254-7255 CD denotes 5
T3519 7255-7256 NN denotes %
T3520 7257-7263 JJ denotes nonfat
T3521 7264-7267 JJ denotes dry
T3522 7268-7272 NN denotes milk
T3523 7273-7275 IN denotes in
T3524 7276-7282 NN denotes saline
T3525 7283-7289 NN denotes buffer
T3526 7290-7299 RB denotes overnight
T3527 7300-7302 IN denotes at
T3528 7303-7306 NN denotes 4°C
T3529 7306-7307 -COMMA- denotes ,
T3530 7308-7311 CC denotes and
T3531 7312-7315 DT denotes the
T3532 7316-7325 VB denotes following
T3533 7326-7336 NN denotes antibodies
T3534 7337-7341 VB denotes were
T3535 7342-7346 VB denotes used
T3536 7346-7347 -COLON- denotes :
T3537 7348-7360 JJ denotes anti-β-actin
T3538 7361-7362 -LRB- denotes (
T3539 7362-7371 NN denotes sc-130657
T3540 7371-7372 -COMMA- denotes ,
T3541 7373-7378 NNP denotes Santa
T3542 7379-7383 NNP denotes Cruz
T3543 7384-7397 NNP denotes Biotechnology
T3544 7397-7398 -COMMA- denotes ,
T3545 7399-7401 NNP denotes CA
T3546 7401-7402 -COMMA- denotes ,
T3547 7403-7406 NNP denotes USA
T3548 7406-7407 -COMMA- denotes ,
T3549 7408-7410 CD denotes 43
T3550 7411-7414 NN denotes kDa
T3551 7414-7415 -RRB- denotes )
T3552 7416-7419 CC denotes and
T3553 7420-7431 JJ denotes anti-matrix
T3554 7432-7448 NN denotes metallopeptidase
T3555 7449-7450 CD denotes 9
T3556 7451-7452 -LRB- denotes (
T3557 7452-7456 NN denotes MMP9
T3558 7456-7457 -RRB- denotes )
T3559 7458-7459 -LRB- denotes (
T3560 7459-7466 NN denotes sc-6841
T3561 7466-7467 -COMMA- denotes ,
T3562 7468-7473 NNP denotes Santa
T3563 7474-7478 NNP denotes Cruz
T3564 7479-7492 NNP denotes Biotechnology
T3565 7492-7493 -COMMA- denotes ,
T3566 7494-7496 NNP denotes CA
T3567 7496-7497 -COMMA- denotes ,
T3568 7498-7501 NNP denotes USA
T3569 7501-7502 -COMMA- denotes ,
T3570 7503-7505 CD denotes 92
T3571 7506-7509 NN denotes kDa
T3572 7509-7510 -RRB- denotes )
T3573 7512-7516 DT denotes Each
T3574 7517-7524 JJ denotes primary
T3575 7525-7533 NN denotes antibody
T3576 7534-7537 VB denotes was
T3577 7538-7545 VB denotes diluted
T3578 7546-7559 RB denotes appropriately
T3579 7560-7562 IN denotes in
T3580 7563-7571 VB denotes blocking
T3581 7572-7578 NN denotes buffer
T3582 7579-7582 CC denotes and
T3583 7583-7587 RB denotes then
T3584 7588-7593 VB denotes added
T3585 7594-7596 TO denotes to
T3586 7597-7600 DT denotes the
T3587 7601-7606 NN denotes blots
T3588 7607-7610 IN denotes for
T3589 7611-7612 CD denotes 1
T3590 7613-7614 NN denotes h
T3591 7615-7617 IN denotes at
T3592 7618-7622 NN denotes room
T3593 7623-7634 NN denotes temperature
T3594 7636-7639 DT denotes The
T3595 7640-7645 NN denotes blots
T3596 7646-7650 VB denotes were
T3597 7651-7657 VB denotes washed
T3598 7658-7663 CD denotes three
T3599 7664-7669 NN denotes times
T3600 7670-7672 IN denotes in
T3601 7673-7676 DT denotes the
T3602 7677-7684 VB denotes washing
T3603 7685-7691 NN denotes buffer
T3604 7692-7695 CC denotes and
T3605 7696-7703 VB denotes covered
T3606 7704-7708 IN denotes with
T3607 7709-7712 DT denotes the
T3608 7713-7724 JJ denotes horseradish
T3609 7725-7742 JJ denotes peroxidase-linked
T3610 7743-7752 JJ denotes secondary
T3611 7753-7761 NN denotes antibody
T3612 7762-7764 IN denotes at
T3613 7765-7766 DT denotes a
T3614 7767-7768 CD denotes 1
T3615 7769-7770 -COLON- denotes :
T3616 7771-7775 CD denotes 2000
T3617 7776-7784 NN denotes dilution
T3618 7785-7788 IN denotes for
T3619 7789-7790 CD denotes 1
T3620 7791-7792 NN denotes h
T3621 7794-7799 NN denotes Blots
T3622 7800-7804 VB denotes were
T3623 7805-7814 VB denotes incubated
T3624 7815-7819 IN denotes with
T3625 7820-7828 VB denotes enhanced
T3626 7829-7846 NN denotes chemiluminescence
T3627 7847-7848 -LRB- denotes (
T3628 7848-7851 NN denotes ECL
T3629 7851-7852 -RRB- denotes )
T3630 7853-7862 NN denotes detection
T3631 7863-7869 NN denotes system
T3632 7870-7871 -LRB- denotes (
T3633 7871-7879 NNP denotes Amersham
T3634 7880-7891 NNP denotes Biosciences
T3635 7891-7892 -COMMA- denotes ,
T3636 7893-7898 NNP denotes Bucks
T3637 7898-7899 -COMMA- denotes ,
T3638 7900-7902 NNP denotes UK
T3639 7902-7903 -RRB- denotes )
T3640 7904-7907 CC denotes and
T3641 7908-7915 VB denotes exposed
T3642 7916-7918 TO denotes to
T3643 7919-7931 JJ denotes radiographic
T3644 7932-7936 NN denotes film
T3645 7937-7938 -LRB- denotes (
T3646 7938-7942 NNP denotes Fuji
T3647 7943-7952 NNP denotes Hyperfilm
T3648 7952-7953 -COMMA- denotes ,
T3649 7954-7959 NNP denotes Tokyo
T3650 7959-7960 -COMMA- denotes ,
T3651 7961-7966 NNP denotes Japan
T3652 7966-7967 -RRB- denotes )
T3653 7969-7975 NN denotes ImageJ
T3654 7976-7979 VB denotes was
T3655 7980-7984 VB denotes used
T3656 7985-7987 TO denotes to
T3657 7988-7995 VB denotes analyze
T3658 7996-7999 DT denotes the
T3659 8000-8009 NN denotes intensity
T3660 8010-8012 IN denotes of
T3661 8013-8016 DT denotes the
T3662 8017-8022 NN denotes blots
T3663 8024-8027 DT denotes The
T3664 8028-8033 NN denotes level
T3665 8034-8036 IN denotes of
T3666 8037-8044 NN denotes β-actin
T3667 8045-8048 VB denotes was
T3668 8049-8053 VB denotes used
T3669 8054-8056 IN denotes as
T3670 8057-8065 JJ denotes internal
T3671 8066-8074 NN denotes standard
T4081 8077-8080 CD denotes 2.7
T4082 8082-8095 JJ denotes Enzyme-Linked
T4083 8096-8109 JJ denotes Immunosorbent
T4084 8110-8115 NN denotes Assay
T4085 8116-8117 -LRB- denotes (
T4086 8117-8122 NN denotes ELISA
T4087 8122-8123 -RRB- denotes )
T4088 8124-8129 NN denotes Cells
T4089 8130-8132 IN denotes of
T4090 8133-8137 CD denotes four
T4091 8138-8144 NN denotes groups
T4092 8145-8149 VB denotes were
T4093 8150-8161 VB denotes homogenized
T4094 8162-8164 IN denotes as
T4095 8165-8174 VB denotes mentioned
T4096 8175-8180 IN denotes above
T4097 8182-8185 DT denotes The
T4098 8186-8197 NN denotes supernatant
T4099 8198-8201 VB denotes was
T4100 8202-8211 VB denotes collected
T4101 8211-8212 -COMMA- denotes ,
T4102 8213-8216 CC denotes and
T4103 8217-8222 JJ denotes total
T4104 8223-8230 NN denotes protein
T4105 8231-8234 VB denotes was
T4106 8235-8245 VB denotes determined
T4107 8246-8248 IN denotes by
T4108 8249-8258 NNP denotes Coomassie
T4109 8259-8263 NNP denotes Plus
T4110 8264-8271 NNP denotes Protein
T4111 8272-8277 NNP denotes Assay
T4112 8278-8285 NNP denotes Reagent
T4113 8286-8287 -LRB- denotes (
T4114 8287-8293 NNP denotes Pierce
T4115 8293-8294 -COMMA- denotes ,
T4116 8295-8297 NNP denotes IL
T4117 8297-8298 -COMMA- denotes ,
T4118 8299-8302 NNP denotes USA
T4119 8302-8303 -RRB- denotes )
T4120 8305-8311 NN denotes Levels
T4121 8312-8314 IN denotes of
T4122 8315-8320 NN denotes tumor
T4123 8321-8329 NN denotes necrosis
T4124 8330-8342 NN denotes factor-alpha
T4125 8343-8344 -LRB- denotes (
T4126 8344-8349 NN denotes TNF-α
T4127 8349-8350 -RRB- denotes )
T4128 8350-8351 -COMMA- denotes ,
T4129 8352-8365 NN denotes interleukin-1
T4130 8366-8370 NN denotes beta
T4131 8371-8372 -LRB- denotes (
T4132 8372-8377 NN denotes IL-1β
T4133 8377-8378 -RRB- denotes )
T4134 8378-8379 -COMMA- denotes ,
T4135 8380-8383 CC denotes and
T4136 8384-8397 NN denotes interleukin-6
T4137 8398-8399 -LRB- denotes (
T4138 8399-8403 NN denotes IL-6
T4139 8403-8404 -RRB- denotes )
T4140 8405-8412 NN denotes protein
T4141 8413-8417 VB denotes were
T4142 8418-8428 VB denotes quantified
T4143 8429-8434 VB denotes using
T4144 8435-8440 NN denotes ELISA
T4145 8441-8445 NN denotes kits
T4146 8446-8454 JJ denotes specific
T4147 8455-8458 IN denotes for
T4148 8459-8464 NN denotes mouse
T4149 8465-8474 VB denotes according
T4150 8475-8477 TO denotes to
T4151 8478-8481 DT denotes the
T4152 8482-8494 NN denotes manufacturer
T4153 8494-8496 POS denotes 's
T4154 8497-8509 NN denotes instructions
T4155 8510-8511 -LRB- denotes (
T4156 8511-8517 NNP denotes Bender
T4157 8518-8528 NNP denotes MedSystems
T4158 8529-8533 NNP denotes Inc.
T4159 8534-8536 NNP denotes CA
T4160 8536-8537 -COMMA- denotes ,
T4161 8538-8541 NNP denotes USA
T4162 8541-8542 -RRB- denotes )
T4163 8544-8551 NNP denotes Briefly
T4164 8551-8552 -COMMA- denotes ,
T4165 8553-8561 VB denotes prepared
T4166 8562-8565 DT denotes the
T4167 8566-8574 NN denotes standard
T4168 8575-8578 CC denotes and
T4169 8579-8586 VB denotes created
T4170 8587-8590 DT denotes the
T4171 8591-8599 JJ denotes standard
T4172 8600-8608 NN denotes dilution
T4173 8609-8612 IN denotes for
T4174 8613-8621 VB denotes building
T4175 8622-8630 JJ denotes standard
T4176 8631-8636 NN denotes curve
T4177 8638-8642 RB denotes Then
T4178 8643-8650 NN denotes samples
T4179 8651-8654 CC denotes and
T4180 8655-8670 NN denotes biotinconjugate
T4181 8671-8675 VB denotes were
T4182 8676-8681 VB denotes added
T4183 8682-8684 TO denotes to
T4184 8685-8694 VB denotes microwell
T4185 8695-8701 NN denotes strips
T4186 8703-8708 IN denotes After
T4187 8709-8718 VB denotes incubated
T4188 8719-8722 IN denotes for
T4189 8723-8724 CD denotes 2
T4190 8725-8726 NN denotes h
T4191 8727-8729 IN denotes at
T4192 8730-8734 NN denotes room
T4193 8735-8746 NN denotes temperature
T4194 8746-8747 -COMMA- denotes ,
T4195 8748-8751 DT denotes the
T4196 8752-8761 NN denotes microwell
T4197 8762-8768 NN denotes strips
T4198 8769-8773 VB denotes were
T4199 8774-8780 VB denotes washed
T4200 8781-8782 CD denotes 3
T4201 8783-8788 NN denotes times
T4202 8789-8793 IN denotes with
T4203 8794-8798 NN denotes wash
T4204 8799-8805 NN denotes buffer
T4205 8805-8806 -COMMA- denotes ,
T4206 8807-8810 CC denotes and
T4207 8811-8827 NN denotes streptavidin-HRP
T4208 8828-8832 VB denotes were
T4209 8833-8838 VB denotes added
T4210 8839-8841 TO denotes to
T4211 8842-8845 DT denotes all
T4212 8846-8851 NN denotes wells
T4213 8853-8858 IN denotes After
T4214 8859-8868 VB denotes incubated
T4215 8869-8872 IN denotes for
T4216 8873-8874 CD denotes 1
T4217 8875-8876 NN denotes h
T4218 8876-8877 -COMMA- denotes ,
T4219 8878-8887 NN denotes microwell
T4220 8888-8894 NN denotes strips
T4221 8895-8899 VB denotes were
T4222 8900-8906 VB denotes washed
T4223 8907-8908 CD denotes 3
T4224 8909-8914 NN denotes times
T4225 8915-8923 VB denotes followed
T4226 8924-8926 IN denotes by
T4227 8927-8933 VB denotes adding
T4228 8934-8937 NN denotes TMB
T4229 8938-8947 NN denotes substrate
T4230 8949-8954 IN denotes After
T4231 8955-8964 VB denotes incubated
T4232 8965-8968 IN denotes for
T4233 8969-8974 RB denotes about
T4234 8975-8980 CD denotes 10–30
T4235 8981-8984 NN denotes min
T4236 8984-8985 -COMMA- denotes ,
T4237 8986-8989 DT denotes the
T4238 8990-8994 NN denotes stop
T4239 8995-9003 NN denotes solution
T4240 9004-9007 VB denotes was
T4241 9008-9013 VB denotes added
T4242 9015-9018 DT denotes The
T4243 9019-9025 NN denotes colour
T4244 9026-9035 NN denotes intensity
T4245 9036-9039 VB denotes was
T4246 9040-9048 VB denotes measured
T4247 9049-9051 IN denotes at
T4248 9052-9055 CD denotes 450
T4249 9056-9058 NN denotes nm
T4250 9059-9064 VB denotes using
T4251 9065-9066 DT denotes a
T4252 9067-9074 JJ denotes Bio-Rad
T4253 9075-9080 NN denotes ELISA
T4254 9081-9091 NN denotes microplate
T4255 9092-9098 NN denotes reader
T4256 9099-9100 -LRB- denotes (
T4257 9100-9107 NNP denotes Bio-Rad
T4258 9108-9120 NNP denotes Laboratories
T4259 9120-9121 -COMMA- denotes ,
T4260 9122-9124 NNP denotes CA
T4261 9124-9125 -COMMA- denotes ,
T4262 9126-9129 NNP denotes USA
T4263 9129-9130 -RRB- denotes )
T4264 9132-9135 DT denotes The
T4265 9136-9149 NN denotes concentration
T4266 9150-9152 IN denotes of
T4267 9153-9160 NN denotes protein
T4268 9161-9164 VB denotes was
T4269 9165-9175 VB denotes determined
T4270 9176-9185 VB denotes according
T4271 9186-9188 TO denotes to
T4272 9189-9192 DT denotes the
T4273 9193-9201 JJ denotes standard
T4274 9202-9207 NN denotes curve
T4275 9208-9211 CC denotes and
T4276 9212-9221 VB denotes expressed
T4277 9222-9224 IN denotes as
T4278 9225-9230 NN denotes pg/mg
T4279 9231-9233 IN denotes of
T4280 9234-9239 JJ denotes total
T4281 9240-9247 NN denotes protein
T4392 9250-9253 CD denotes 2.8
T4393 9255-9263 NN denotes Gelatine
T4394 9264-9274 NN denotes Zymography
T4395 9275-9280 NN denotes Cells
T4396 9281-9283 IN denotes of
T4397 9284-9288 CD denotes four
T4398 9289-9295 NN denotes groups
T4399 9296-9300 VB denotes were
T4400 9301-9312 VB denotes homogenized
T4401 9313-9315 IN denotes in
T4402 9316-9321 NN denotes lysis
T4403 9322-9328 NN denotes buffer
T4404 9329-9339 VB denotes containing
T4405 9340-9342 CD denotes 50
T4406 9343-9345 NN denotes mM
T4407 9346-9354 NN denotes Tris-HCl
T4408 9355-9356 -LRB- denotes (
T4409 9356-9358 NN denotes pH
T4410 9359-9362 CD denotes 7.4
T4411 9362-9363 -RRB- denotes )
T4412 9363-9364 -COMMA- denotes ,
T4413 9365-9368 CD denotes 150
T4414 9369-9371 NN denotes mM
T4415 9372-9376 NN denotes NaCl
T4416 9376-9377 -COMMA- denotes ,
T4417 9378-9379 CD denotes 5
T4418 9380-9382 NN denotes mM
T4419 9383-9388 NN denotes CaCl2
T4420 9388-9389 -COMMA- denotes ,
T4421 9390-9393 CD denotes 0.2
T4422 9394-9396 NN denotes mM
T4423 9397-9401 NN denotes NaN3
T4424 9401-9402 -COMMA- denotes ,
T4425 9403-9406 CC denotes and
T4426 9407-9411 CD denotes 0.01
T4427 9411-9412 NN denotes %
T4428 9413-9420 NNP denotes Triton.
T4429 9421-9428 NNP denotes Soluble
T4430 9429-9437 NN denotes extracts
T4431 9438-9442 VB denotes were
T4432 9443-9452 VB denotes separated
T4433 9453-9455 IN denotes by
T4434 9456-9470 NN denotes centrifugation
T4435 9471-9474 CC denotes and
T4436 9475-9481 VB denotes stored
T4437 9482-9484 IN denotes at
T4438 9485-9490 NN denotes –20°C
T4439 9492-9499 NN denotes Gelatin
T4440 9500-9510 NN denotes zymography
T4441 9511-9514 VB denotes was
T4442 9515-9524 VB denotes performed
T4443 9525-9534 VB denotes according
T4444 9535-9537 TO denotes to
T4445 9538-9541 DT denotes the
T4446 9542-9554 NN denotes manufacturer
T4447 9554-9556 POS denotes 's
T4448 9557-9569 NN denotes instructions
T4449 9570-9571 -LRB- denotes (
T4450 9571-9577 NNP denotes Genmed
T4451 9578-9589 NNP denotes Scientifics
T4452 9590-9593 NNP denotes Inc
T4453 9593-9594 -COMMA- denotes ,
T4454 9595-9597 NNP denotes MA
T4455 9597-9598 -COMMA- denotes ,
T4456 9599-9602 NNP denotes USA
T4457 9602-9603 -RRB- denotes )
T4458 9605-9612 RB denotes Briefly
T4459 9612-9613 -COMMA- denotes ,
T4460 9614-9616 CD denotes 40
T4461 9617-9619 NN denotes μg
T4462 9620-9629 JJ denotes cytosolic
T4463 9630-9637 NN denotes protein
T4464 9638-9646 NN denotes extracts
T4465 9647-9651 VB denotes were
T4466 9652-9661 VB denotes separated
T4467 9662-9664 IN denotes by
T4468 9665-9680 NN denotes electrophoresis
T4469 9682-9686 RB denotes Then
T4470 9687-9690 DT denotes the
T4471 9691-9699 NN denotes proteins
T4472 9700-9704 VB denotes were
T4473 9705-9714 VB denotes renatured
T4474 9715-9717 IN denotes by
T4475 9718-9728 NN denotes incubation
T4476 9729-9731 IN denotes in
T4477 9732-9735 CD denotes 2.5
T4478 9735-9736 NN denotes %
T4479 9737-9743 NN denotes Triton
T4480 9744-9749 NN denotes X-100
T4481 9750-9753 CC denotes and
T4482 9754-9758 RB denotes then
T4483 9759-9768 VB denotes incubated
T4484 9769-9771 IN denotes in
T4485 9772-9781 NN denotes substrate
T4486 9782-9788 NN denotes buffer
T4487 9789-9792 IN denotes for
T4488 9793-9795 CD denotes 40
T4489 9796-9797 NN denotes h
T4490 9798-9800 IN denotes at
T4491 9801-9805 NN denotes 37°C
T4492 9806-9808 TO denotes to
T4493 9809-9815 VB denotes enable
T4494 9816-9819 DT denotes the
T4495 9820-9824 NN denotes MMP9
T4496 9825-9827 TO denotes to
T4497 9828-9834 VB denotes cleave
T4498 9835-9838 DT denotes the
T4499 9839-9846 NN denotes gelatin
T4500 9848-9853 IN denotes After
T4501 9854-9861 VB denotes rinsing
T4502 9862-9864 IN denotes in
T4503 9865-9870 NN denotes water
T4504 9870-9871 -COMMA- denotes ,
T4505 9872-9876 DT denotes each
T4506 9877-9880 NN denotes gel
T4507 9881-9884 VB denotes was
T4508 9885-9892 VB denotes stained
T4509 9893-9897 IN denotes with
T4510 9898-9907 NNP denotes Coomassie
T4511 9908-9912 JJ denotes blue
T4512 9913-9916 IN denotes for
T4513 9917-9918 CD denotes 1
T4514 9919-9920 NN denotes h
T4515 9921-9924 CC denotes and
T4516 9925-9934 VB denotes destained
T4517 9935-9937 IN denotes in
T4518 9938-9940 CD denotes 50
T4519 9940-9941 NN denotes %
T4520 9942-9950 NN denotes methanol
T4521 9952-9963 JJ denotes Proteolytic
T4522 9964-9974 NN denotes activities
T4523 9975-9979 VB denotes were
T4524 9980-9986 VB denotes showed
T4525 9987-9989 IN denotes by
T4526 9990-9995 JJ denotes clear
T4527 9996-10001 NN denotes bands
T4528 10002-10004 IN denotes in
T4529 10005-10009 JJ denotes blue
T4530 10010-10013 NN denotes gel
T4531 10014-10019 WDT denotes which
T4532 10020-10029 VB denotes indicates
T4533 10030-10033 DT denotes the
T4534 10034-10039 NN denotes lysis
T4535 10040-10042 IN denotes of
T4536 10043-10046 DT denotes the
T4537 10047-10056 NN denotes substrate
T4538 10058-10072 NN denotes Quantification
T4539 10073-10075 IN denotes of
T4540 10076-10080 NN denotes MMP9
T4541 10081-10085 NN denotes band
T4542 10086-10093 NN denotes density
T4543 10094-10097 VB denotes was
T4544 10098-10107 VB denotes performed
T4545 10108-10112 IN denotes with
T4546 10113-10118 NN denotes image
T4547 10119-10127 NN denotes analysis
T4548 10128-10135 NN denotes program
T4549 10136-10142 NN denotes ImageJ
T4762 10145-10148 CD denotes 2.9
T4763 10150-10161 JJ denotes Statistical
T4764 10162-10170 NN denotes Analysis
T4765 10171-10175 NN denotes Data
T4766 10176-10180 VB denotes were
T4767 10181-10190 VB denotes expressed
T4768 10191-10193 IN denotes as
T4769 10194-10198 NN denotes mean
T4770 10199-10200 SYM denotes ±
T4771 10201-10203 NN denotes SD
T4772 10204-10207 CC denotes and
T4773 10208-10217 VB denotes evaluated
T4774 10218-10220 IN denotes by
T4775 10221-10226 NN denotes ANOVA
T4776 10227-10230 CC denotes and
T4777 10231-10234 NN denotes LSD
T4778 10235-10243 JJ denotes multiple
T4779 10244-10254 NN denotes comparison
T4780 10255-10259 NN denotes test
T4781 10261-10262 NN denotes P
T4782 10263-10269 NN denotes values
T4783 10270-10271 SYM denotes <
T4784 10271-10275 CD denotes 0.05
T4785 10276-10280 VB denotes were
T4786 10281-10291 VB denotes considered
T4787 10292-10294 TO denotes to
T4788 10295-10297 VB denotes be
T4789 10298-10309 JJ denotes significant
T4790 10311-10314 DT denotes All
T4791 10315-10323 NN denotes analyses
T4792 10324-10328 VB denotes were
T4793 10329-10338 VB denotes performed
T4794 10339-10341 IN denotes by
T4795 10342-10347 VB denotes using
T4796 10348-10352 NN denotes SPSS
T4797 10353-10357 CD denotes 18.0
T4798 10358-10366 NN denotes software
T4856 10381-10384 CD denotes 3.1
T4857 10386-10395 NN denotes Depletion
T4858 10396-10398 IN denotes of
T4859 10399-10403 NN denotes Nrf2
T4860 10404-10414 VB denotes Aggravated
T4861 10415-10418 DT denotes the
T4862 10419-10423 NNP denotes Cell
T4863 10424-10429 NNP denotes Death
T4864 10430-10432 IN denotes in
T4865 10433-10443 NN denotes Astrocytes
T4866 10444-10449 IN denotes after
T4867 10450-10457 NNP denotes Scratch
T4868 10458-10464 NNP denotes Injury
T4869 10465-10469 NN denotes Cell
T4870 10470-10475 NN denotes death
T4871 10476-10479 VB denotes was
T4872 10480-10488 VB denotes detected
T4873 10489-10491 IN denotes by
T4874 10492-10502 NN denotes microscope
T4875 10503-10506 CC denotes and
T4876 10507-10512 NN denotes CCK-8
T4877 10513-10521 NN denotes analysis
T4878 10522-10524 IN denotes at
T4879 10525-10527 CD denotes 24
T4880 10528-10529 NN denotes h
T4881 10530-10535 IN denotes after
T4882 10536-10543 NN denotes scratch
T4883 10545-10548 DT denotes The
T4884 10549-10559 NN denotes detachment
T4885 10560-10564 IN denotes from
T4886 10565-10572 NN denotes culture
T4887 10573-10578 NN denotes plate
T4888 10578-10579 -COMMA- denotes ,
T4889 10580-10584 NN denotes cell
T4890 10585-10589 NN denotes lost
T4891 10589-10590 -COMMA- denotes ,
T4892 10591-10594 CC denotes and
T4893 10595-10606 JJ denotes cytoplasmic
T4894 10607-10614 NN denotes process
T4895 10615-10625 NN denotes distortion
T4896 10626-10630 VB denotes were
T4897 10631-10637 RB denotes mostly
T4898 10638-10646 VB denotes observed
T4899 10647-10649 IN denotes in
T4900 10650-10654 DT denotes both
T4901 10655-10660 NN denotes sides
T4902 10661-10663 IN denotes of
T4903 10664-10671 NN denotes scratch
T4904 10672-10676 NN denotes line
T4905 10677-10679 IN denotes in
T4906 10680-10685 NN denotes group
T4907 10686-10688 NNP denotes KO
T4908 10689-10692 NNP denotes TBI
T4909 10694-10699 NN denotes CCK-8
T4910 10700-10705 NN denotes assay
T4911 10706-10710 RB denotes also
T4912 10711-10717 VB denotes showed
T4913 10718-10723 JJ denotes lower
T4914 10724-10726 NN denotes OD
T4915 10727-10732 NN denotes value
T4916 10733-10735 IN denotes of
T4917 10736-10741 NN denotes group
T4918 10742-10744 NN denotes KO
T4919 10745-10748 NN denotes TBI
T4920 10749-10750 -LRB- denotes (
T4921 10750-10754 CD denotes 0.38
T4922 10755-10756 CC denotes ±
T4923 10757-10762 CD denotes 0.064
T4924 10762-10763 -RRB- denotes )
T4925 10764-10768 IN denotes than
T4926 10769-10773 DT denotes that
T4927 10774-10776 IN denotes of
T4928 10777-10782 NN denotes group
T4929 10783-10785 NN denotes WT
T4930 10786-10789 NN denotes TBI
T4931 10790-10791 -LRB- denotes (
T4932 10791-10795 CD denotes 0.98
T4933 10796-10797 CC denotes ±
T4934 10798-10803 CD denotes 0.098
T4935 10803-10804 -RRB- denotes )
T4936 10805-10806 -LRB- denotes (
T4937 10806-10807 NN denotes P
T4938 10808-10809 SYM denotes <
T4939 10810-10814 CD denotes 0.01
T4940 10814-10815 -RRB- denotes )
T4941 10815-10816 -COMMA- denotes ,
T4942 10817-10822 WDT denotes which
T4943 10823-10827 RB denotes also
T4944 10828-10837 VB denotes suggested
T4945 10838-10842 JJ denotes more
T4946 10843-10847 NN denotes cell
T4947 10848-10853 NN denotes death
T4948 10854-10856 IN denotes in
T4949 10857-10862 NN denotes group
T4950 10863-10865 NN denotes KO
T4951 10866-10869 NN denotes TBI
T4952 10870-10871 -LRB- denotes (
T4953 10871-10877 NN denotes Figure
T4954 10878-10879 CD denotes 1
T4955 10879-10880 -RRB- denotes )
T4956 10882-10887 EX denotes There
T4957 10888-10891 VB denotes was
T4958 10892-10894 DT denotes no
T4959 10895-10905 NN denotes difference
T4960 10906-10913 IN denotes between
T4961 10914-10917 CD denotes two
T4962 10918-10931 JJ denotes sham-operated
T4963 10932-10938 NN denotes groups
T5113 10941-10944 CD denotes 3.2
T5114 10946-10956 NN denotes Disruption
T5115 10957-10959 IN denotes of
T5116 10960-10964 NN denotes Nrf2
T5117 10965-10973 VB denotes Enhanced
T5118 10974-10986 NN denotes Upregulation
T5119 10987-10989 IN denotes of
T5120 10990-10995 NN denotes NF-κB
T5121 10996-11007 JJ denotes DNA-Binding
T5122 11008-11016 NN denotes Activity
T5123 11017-11022 IN denotes after
T5124 11023-11030 NNP denotes Scratch
T5125 11031-11037 NNP denotes Injury
T5126 11038-11040 PRP denotes It
T5127 11041-11044 VB denotes has
T5128 11045-11049 VB denotes been
T5129 11050-11058 VB denotes reported
T5130 11059-11063 IN denotes that
T5131 11064-11069 NN denotes NF-κB
T5132 11070-11072 VB denotes is
T5133 11073-11082 VB denotes activated
T5134 11083-11085 IN denotes in
T5135 11086-11091 NN denotes brain
T5136 11092-11097 IN denotes after
T5137 11098-11101 NNP denotes TBI
T5138 11102-11103 -LRB- denotes [
T5139 11103-11104 CD denotes 2
T5140 11104-11105 -RRB- denotes ]
T5141 11107-11111 RB denotes Here
T5142 11111-11112 -COMMA- denotes ,
T5143 11113-11115 PRP denotes we
T5144 11116-11123 VB denotes studied
T5145 11124-11127 DT denotes the
T5146 11128-11139 JJ denotes DNA-binding
T5147 11140-11148 NN denotes activity
T5148 11149-11151 IN denotes of
T5149 11152-11157 NN denotes NF-κB
T5150 11158-11160 IN denotes of
T5151 11161-11171 NN denotes astrocytes
T5152 11172-11176 IN denotes from
T5153 11177-11181 NN denotes Nrf2
T5154 11182-11184 NN denotes WT
T5155 11185-11187 CC denotes or
T5156 11188-11190 NN denotes KO
T5157 11191-11195 NN denotes mice
T5158 11196-11198 IN denotes by
T5159 11199-11203 NN denotes EMSA
T5160 11204-11206 IN denotes at
T5161 11207-11209 CD denotes 24
T5162 11210-11211 NN denotes h
T5163 11212-11217 IN denotes after
T5164 11218-11225 NN denotes scratch
T5165 11226-11232 NN denotes injury
T5166 11234-11241 NN denotes Scratch
T5167 11242-11248 NN denotes injury
T5168 11249-11256 VB denotes induced
T5169 11257-11267 NN denotes activation
T5170 11268-11270 IN denotes of
T5171 11271-11276 NN denotes NF-κB
T5172 11277-11279 IN denotes in
T5173 11280-11290 NN denotes astrocytes
T5174 11291-11293 IN denotes of
T5175 11294-11298 DT denotes both
T5176 11299-11308 NN denotes genotypes
T5177 11308-11309 -COMMA- denotes ,
T5178 11310-11315 IN denotes while
T5179 11316-11322 JJ denotes higher
T5180 11323-11328 NN denotes NF-κB
T5181 11329-11337 NN denotes activity
T5182 11338-11341 VB denotes was
T5183 11342-11350 VB denotes observed
T5184 11351-11353 IN denotes in
T5185 11354-11359 NN denotes group
T5186 11360-11362 NN denotes KO
T5187 11363-11366 NN denotes TBI
T5188 11367-11371 IN denotes than
T5189 11372-11374 IN denotes in
T5190 11375-11380 NN denotes group
T5191 11381-11383 NN denotes WT
T5192 11384-11387 NN denotes TBI
T5193 11388-11389 -LRB- denotes (
T5194 11389-11393 CD denotes 2.67
T5195 11394-11395 SYM denotes ±
T5196 11396-11401 CD denotes 0.173
T5197 11402-11408 IN denotes versus
T5198 11409-11413 CD denotes 2.28
T5199 11414-11415 SYM denotes ±
T5200 11416-11421 CD denotes 0.072
T5201 11421-11422 -COMMA- denotes ,
T5202 11423-11424 NN denotes P
T5203 11425-11426 SYM denotes <
T5204 11427-11431 CD denotes 0.01
T5205 11431-11432 -RRB- denotes )
T5206 11433-11434 -LRB- denotes (
T5207 11434-11440 NN denotes Figure
T5208 11441-11442 CD denotes 2
T5209 11442-11443 -RRB- denotes )
T5468 11446-11449 CD denotes 3.3
T5469 11451-11461 NN denotes Expression
T5470 11462-11464 IN denotes of
T5471 11465-11480 JJ denotes Proinflammatory
T5472 11481-11490 NN denotes Cytokines
T5473 11491-11494 VB denotes Was
T5474 11495-11503 VB denotes Elevated
T5475 11504-11506 IN denotes in
T5476 11507-11511 NN denotes Nrf2
T5477 11512-11520 NNP denotes Knockout
T5478 11521-11531 NN denotes Astrocytes
T5479 11532-11537 IN denotes after
T5480 11538-11545 NNP denotes Scratch
T5481 11546-11552 NNP denotes Injury
T5482 11553-11555 IN denotes As
T5483 11556-11558 PRP denotes we
T5484 11559-11562 DT denotes all
T5485 11563-11567 VB denotes know
T5486 11567-11568 -COMMA- denotes ,
T5487 11569-11574 NN denotes TNF-α
T5488 11574-11575 -COMMA- denotes ,
T5489 11576-11581 NN denotes IL-1β
T5490 11581-11582 -COMMA- denotes ,
T5491 11583-11586 CC denotes and
T5492 11587-11591 NN denotes IL-6
T5493 11592-11595 VB denotes are
T5494 11596-11605 VB denotes regulated
T5495 11606-11608 IN denotes by
T5496 11609-11614 NN denotes NF-κB
T5497 11615-11618 CC denotes and
T5498 11619-11626 VB denotes reflect
T5499 11627-11630 DT denotes the
T5500 11631-11641 JJ denotes endogenous
T5501 11642-11650 NN denotes activity
T5502 11651-11653 IN denotes of
T5503 11654-11659 NN denotes NF-κB
T5504 11661-11663 PRP denotes It
T5505 11664-11667 VB denotes has
T5506 11668-11672 VB denotes been
T5507 11673-11681 VB denotes revealed
T5508 11682-11686 IN denotes that
T5509 11687-11692 DT denotes these
T5510 11693-11708 JJ denotes proinflammatory
T5511 11709-11718 NN denotes cytokines
T5512 11719-11722 VB denotes are
T5513 11723-11732 VB denotes increased
T5514 11733-11738 IN denotes after
T5515 11739-11742 NN denotes TBI
T5516 11743-11745 IN denotes in
T5517 11746-11753 NN denotes animals
T5518 11754-11755 -LRB- denotes [
T5519 11755-11756 CD denotes 2
T5520 11756-11757 -COMMA- denotes ,
T5521 11758-11759 CD denotes 8
T5522 11759-11760 -RRB- denotes ]
T5523 11762-11765 CC denotes And
T5524 11766-11769 PRP-DOLLAR- denotes our
T5525 11770-11778 JJ denotes previous
T5526 11779-11784 NN denotes study
T5527 11785-11788 VB denotes has
T5528 11789-11795 VB denotes proved
T5529 11796-11800 IN denotes that
T5530 11801-11807 JJ denotes higher
T5531 11808-11814 NN denotes levels
T5532 11815-11817 IN denotes of
T5533 11818-11822 JJ denotes such
T5534 11823-11838 JJ denotes proinflammatory
T5535 11839-11848 NN denotes cytokines
T5536 11849-11853 VB denotes were
T5537 11854-11862 VB denotes observed
T5538 11863-11865 IN denotes in
T5539 11866-11869 DT denotes the
T5540 11870-11875 NN denotes brain
T5541 11876-11878 IN denotes of
T5542 11879-11893 JJ denotes Nrf2-deficient
T5543 11894-11898 NN denotes mice
T5544 11899-11904 IN denotes after
T5545 11905-11908 NNP denotes TBI
T5546 11909-11910 -LRB- denotes [
T5547 11910-11911 CD denotes 5
T5548 11911-11912 -RRB- denotes ]
T5549 11914-11917 CC denotes But
T5550 11918-11920 PRP denotes it
T5551 11921-11923 VB denotes is
T5552 11924-11929 RB denotes still
T5553 11930-11939 JJ denotes ambiguous
T5554 11940-11945 IN denotes about
T5555 11946-11949 DT denotes the
T5556 11950-11962 NN denotes relationship
T5557 11963-11970 IN denotes between
T5558 11971-11976 DT denotes these
T5559 11977-11986 NN denotes cytokines
T5560 11987-11990 CC denotes and
T5561 11991-11995 NN denotes Nrf2
T5562 11996-11998 IN denotes in
T5563 11999-12009 NN denotes astrocytes
T5564 12010-12015 IN denotes after
T5565 12016-12019 NN denotes TBI
T5566 12021-12025 RB denotes Here
T5567 12025-12026 -COMMA- denotes ,
T5568 12027-12029 PRP denotes we
T5569 12030-12036 VB denotes tested
T5570 12037-12040 DT denotes the
T5571 12041-12047 NN denotes levels
T5572 12048-12050 IN denotes of
T5573 12051-12056 NN denotes TNF-α
T5574 12056-12057 -COMMA- denotes ,
T5575 12058-12063 NN denotes IL-1β
T5576 12063-12064 -COMMA- denotes ,
T5577 12065-12068 CC denotes and
T5578 12069-12073 NN denotes IL-6
T5579 12074-12076 IN denotes in
T5580 12077-12085 VB denotes cultured
T5581 12086-12096 NN denotes astrocytes
T5582 12097-12099 IN denotes at
T5583 12100-12102 CD denotes 24
T5584 12103-12104 NN denotes h
T5585 12105-12110 IN denotes after
T5586 12111-12118 NN denotes scratch
T5587 12119-12125 NN denotes injury
T5588 12126-12128 IN denotes by
T5589 12129-12135 NN denotes RT-PCR
T5590 12136-12139 CC denotes and
T5591 12140-12145 NN denotes ELISA
T5592 12147-12149 PRP denotes It
T5593 12150-12153 VB denotes was
T5594 12154-12159 VB denotes shown
T5595 12160-12164 IN denotes that
T5596 12165-12168 DT denotes the
T5597 12169-12173 NN denotes mRNA
T5598 12174-12180 NN denotes levels
T5599 12181-12183 IN denotes of
T5600 12184-12189 NN denotes TNF-α
T5601 12189-12190 -COMMA- denotes ,
T5602 12191-12196 NN denotes IL-1β
T5603 12196-12197 -COMMA- denotes ,
T5604 12198-12201 CC denotes and
T5605 12202-12206 NN denotes IL-6
T5606 12207-12211 VB denotes were
T5607 12212-12221 VB denotes increased
T5608 12222-12227 IN denotes after
T5609 12228-12235 NN denotes scratch
T5610 12236-12238 IN denotes in
T5611 12239-12243 CC denotes both
T5612 12244-12246 NN denotes WT
T5613 12247-12250 CC denotes and
T5614 12251-12253 NN denotes KO
T5615 12254-12264 NN denotes astrocytes
T5616 12265-12269 WRB denotes when
T5617 12270-12278 VB denotes compared
T5618 12279-12283 IN denotes with
T5619 12284-12289 PRP-DOLLAR- denotes their
T5620 12290-12294 NN denotes sham
T5621 12295-12307 NN denotes counterparts
T5622 12307-12308 -COMMA- denotes ,
T5623 12309-12321 RB denotes respectively
T5624 12323-12331 RB denotes Moreover
T5625 12331-12332 -COMMA- denotes ,
T5626 12333-12336 DT denotes the
T5627 12337-12341 NN denotes mRNA
T5628 12342-12348 NN denotes levels
T5629 12349-12351 IN denotes of
T5630 12352-12357 DT denotes these
T5631 12358-12367 NN denotes cytokines
T5632 12368-12370 IN denotes in
T5633 12371-12376 NN denotes group
T5634 12377-12379 NN denotes KO
T5635 12380-12383 NNP denotes TBI
T5636 12384-12388 VB denotes were
T5637 12389-12393 RB denotes much
T5638 12394-12400 JJ denotes higher
T5639 12401-12405 IN denotes than
T5640 12406-12411 DT denotes those
T5641 12412-12414 IN denotes in
T5642 12415-12420 NN denotes group
T5643 12421-12423 NN denotes WT
T5644 12424-12427 NN denotes TBI
T5645 12428-12429 -LRB- denotes (
T5646 12429-12433 CD denotes 1.66
T5647 12434-12435 SYM denotes ±
T5648 12436-12441 CD denotes 0.085
T5649 12442-12448 IN denotes versus
T5650 12449-12453 CD denotes 1.39
T5651 12454-12455 SYM denotes ±
T5652 12456-12461 CD denotes 0.110
T5653 12462-12465 IN denotes for
T5654 12466-12471 NN denotes TNF-α
T5655 12471-12472 -COMMA- denotes ,
T5656 12473-12477 CD denotes 1.34
T5657 12478-12479 SYM denotes ±
T5658 12480-12485 CD denotes 0.064
T5659 12486-12492 IN denotes versus
T5660 12493-12497 CD denotes 0.73
T5661 12498-12499 SYM denotes ±
T5662 12500-12505 CD denotes 0.088
T5663 12506-12509 IN denotes for
T5664 12510-12515 NN denotes IL-1β
T5665 12515-12516 -COMMA- denotes ,
T5666 12517-12520 CC denotes and
T5667 12521-12525 CD denotes 1.28
T5668 12526-12527 SYM denotes ±
T5669 12528-12533 CD denotes 0.102
T5670 12534-12540 IN denotes versus
T5671 12541-12545 CD denotes 0.99
T5672 12546-12547 SYM denotes ±
T5673 12548-12553 CD denotes 0.073
T5674 12554-12557 IN denotes for
T5675 12558-12562 NN denotes IL-6
T5676 12564-12565 NN denotes P
T5677 12566-12567 SYM denotes <
T5678 12568-12572 CD denotes 0.01
T5679 12572-12573 -RRB- denotes )
T5680 12574-12575 -LRB- denotes (
T5681 12575-12582 NN denotes Figures
T5682 12583-12584 CD denotes 3
T5683 12584-12585 -LRB- denotes (
T5684 12585-12586 DT denotes a
T5685 12586-12587 -RRB- denotes )
T5686 12587-12589 CD denotes –3
T5687 12589-12590 -LRB- denotes (
T5688 12590-12591 NN denotes d
T5689 12591-12592 -RRB- denotes )
T5690 12592-12593 -RRB- denotes )
T5691 12595-12598 DT denotes The
T5692 12599-12606 NN denotes results
T5693 12607-12609 IN denotes of
T5694 12610-12615 NN denotes ELISA
T5695 12616-12624 VB denotes revealed
T5696 12625-12629 IN denotes that
T5697 12630-12633 DT denotes the
T5698 12634-12641 NN denotes protein
T5699 12642-12647 NN denotes level
T5700 12648-12650 IN denotes of
T5701 12651-12656 NN denotes TNF-α
T5702 12657-12660 VB denotes was
T5703 12661-12672 VB denotes upregulated
T5704 12673-12678 IN denotes after
T5705 12679-12686 NN denotes scratch
T5706 12687-12693 NN denotes injury
T5707 12694-12696 IN denotes in
T5708 12697-12699 NN denotes WT
T5709 12700-12703 CC denotes and
T5710 12704-12706 NN denotes KO
T5711 12707-12717 NN denotes astrocytes
T5712 12718-12722 WRB denotes when
T5713 12723-12731 VB denotes compared
T5714 12732-12736 IN denotes with
T5715 12737-12742 PRP-DOLLAR- denotes their
T5716 12743-12747 NN denotes sham
T5717 12748-12760 NN denotes counterparts
T5718 12762-12765 CC denotes And
T5719 12766-12768 PRP denotes it
T5720 12769-12772 VB denotes was
T5721 12773-12777 RB denotes also
T5722 12778-12784 JJ denotes higher
T5723 12785-12787 IN denotes in
T5724 12788-12793 NN denotes group
T5725 12794-12796 NN denotes KO
T5726 12797-12800 NN denotes TBI
T5727 12801-12805 IN denotes than
T5728 12806-12808 IN denotes in
T5729 12809-12814 NN denotes group
T5730 12815-12817 NN denotes WT
T5731 12818-12821 NN denotes TBI
T5732 12822-12823 -LRB- denotes (
T5733 12823-12827 CD denotes 3.67
T5734 12828-12829 SYM denotes ±
T5735 12830-12835 CD denotes 0.156
T5736 12836-12842 IN denotes versus
T5737 12843-12847 CD denotes 2.31
T5738 12848-12849 SYM denotes ±
T5739 12850-12855 CD denotes 0.087
T5740 12855-12856 -COMMA- denotes ,
T5741 12857-12858 NN denotes P
T5742 12859-12860 SYM denotes <
T5743 12861-12865 CD denotes 0.01
T5744 12865-12866 -RRB- denotes )
T5745 12867-12868 -LRB- denotes (
T5746 12868-12874 NN denotes Figure
T5747 12875-12876 CD denotes 4
T5748 12876-12877 -LRB- denotes (
T5749 12877-12878 DT denotes a
T5750 12878-12879 -RRB- denotes )
T5751 12879-12880 -RRB- denotes )
T5752 12882-12889 JJ denotes Similar
T5753 12890-12898 NN denotes tendency
T5754 12899-12902 VB denotes was
T5755 12903-12911 VB denotes observed
T5756 12912-12914 IN denotes in
T5757 12915-12922 NN denotes protein
T5758 12923-12928 NN denotes level
T5759 12929-12931 IN denotes of
T5760 12932-12936 NN denotes IL-6
T5761 12937-12940 CC denotes and
T5762 12941-12946 NN denotes IL-1β
T5763 12948-12951 IN denotes For
T5764 12952-12956 NN denotes IL-6
T5765 12956-12957 -COMMA- denotes ,
T5766 12958-12960 PRP denotes it
T5767 12961-12964 VB denotes was
T5768 12965-12970 CD denotes 36.07
T5769 12971-12972 SYM denotes ±
T5770 12973-12978 CD denotes 0.786
T5771 12979-12982 IN denotes for
T5772 12983-12988 NN denotes group
T5773 12989-12991 NNP denotes KO
T5774 12992-12995 NNP denotes TBI
T5775 12996-13001 IN denotes while
T5776 13002-13007 CD denotes 25.76
T5777 13008-13009 SYM denotes ±
T5778 13010-13015 CD denotes 0.536
T5779 13016-13019 IN denotes for
T5780 13020-13025 NN denotes group
T5781 13026-13028 NN denotes WT
T5782 13029-13032 NN denotes TBI
T5783 13033-13034 -LRB- denotes (
T5784 13034-13035 NN denotes P
T5785 13036-13037 SYM denotes <
T5786 13038-13042 CD denotes 0.01
T5787 13042-13043 -RRB- denotes )
T5788 13044-13045 -LRB- denotes (
T5789 13045-13051 NN denotes Figure
T5790 13052-13053 CD denotes 4
T5791 13053-13054 -LRB- denotes (
T5792 13054-13055 NN denotes b
T5793 13055-13056 -RRB- denotes )
T5794 13056-13057 -RRB- denotes )
T5795 13059-13062 IN denotes For
T5796 13063-13068 NN denotes IL-1β
T5797 13068-13069 -COMMA- denotes ,
T5798 13070-13072 PRP denotes it
T5799 13073-13076 VB denotes was
T5800 13077-13083 CD denotes 190.75
T5801 13084-13085 SYM denotes ±
T5802 13086-13091 CD denotes 6.339
T5803 13092-13095 IN denotes for
T5804 13096-13101 NN denotes group
T5805 13102-13104 NNP denotes KO
T5806 13105-13108 NNP denotes TBI
T5807 13109-13114 IN denotes while
T5808 13115-13121 CD denotes 154.50
T5809 13122-13123 SYM denotes ±
T5810 13124-13129 CD denotes 5.348
T5811 13130-13133 IN denotes for
T5812 13134-13139 NN denotes group
T5813 13140-13142 NN denotes WT
T5814 13143-13146 NN denotes TBI
T5815 13147-13148 -LRB- denotes (
T5816 13148-13149 NN denotes P
T5817 13150-13151 SYM denotes <
T5818 13152-13156 CD denotes 0.01
T5819 13156-13157 -RRB- denotes )
T5820 13158-13159 -LRB- denotes (
T5821 13159-13165 NN denotes Figure
T5822 13166-13167 CD denotes 4
T5823 13167-13168 -LRB- denotes (
T5824 13168-13169 NN denotes c
T5825 13169-13170 -RRB- denotes )
T5826 13170-13171 -RRB- denotes )
T6503 13174-13177 CD denotes 3.4
T6504 13179-13189 NN denotes Expression
T6505 13190-13193 CC denotes and
T6506 13194-13202 NN denotes Activity
T6507 13203-13205 IN denotes of
T6508 13206-13210 NN denotes MMP9
T6509 13211-13215 VB denotes Were
T6510 13216-13223 RB denotes Greatly
T6511 13224-13232 VB denotes Enhanced
T6512 13233-13235 IN denotes in
T6513 13236-13240 NN denotes Nrf2
T6514 13241-13249 NNP denotes Knockout
T6515 13250-13260 NN denotes Astrocytes
T6516 13261-13266 IN denotes after
T6517 13267-13274 NNP denotes Scratch
T6518 13275-13281 NNP denotes Injury
T6519 13282-13286 NN denotes MMP9
T6520 13287-13289 VB denotes is
T6521 13290-13292 DT denotes an
T6522 13293-13302 JJ denotes important
T6523 13303-13313 NN denotes gelatinase
T6524 13314-13316 TO denotes to
T6525 13317-13323 VB denotes induce
T6526 13324-13326 CC denotes or
T6527 13327-13336 VB denotes aggravate
T6528 13337-13340 DT denotes the
T6529 13341-13353 NN denotes inflammation
T6530 13354-13361 NN denotes process
T6531 13363-13365 IN denotes In
T6532 13366-13369 DT denotes the
T6533 13370-13377 JJ denotes present
T6534 13378-13383 NN denotes study
T6535 13383-13384 -COMMA- denotes ,
T6536 13385-13387 PRP denotes we
T6537 13388-13396 VB denotes elevated
T6538 13397-13400 DT denotes the
T6539 13401-13405 NN denotes mRNA
T6540 13405-13406 -COMMA- denotes ,
T6541 13407-13414 NN denotes protein
T6542 13415-13421 NN denotes levels
T6543 13421-13422 -COMMA- denotes ,
T6544 13423-13426 CC denotes and
T6545 13427-13435 NN denotes activity
T6546 13436-13438 IN denotes of
T6547 13439-13443 NN denotes MMP9
T6548 13444-13446 IN denotes in
T6549 13447-13457 NN denotes astrocytes
T6550 13458-13460 IN denotes at
T6551 13461-13463 CD denotes 24
T6552 13464-13465 NN denotes h
T6553 13466-13471 IN denotes after
T6554 13472-13479 NN denotes scratch
T6555 13480-13486 NN denotes injury
T6556 13487-13489 IN denotes by
T6557 13490-13496 NN denotes RT-PCR
T6558 13496-13497 -COMMA- denotes ,
T6559 13498-13505 JJ denotes western
T6560 13506-13510 NN denotes blot
T6561 13510-13511 -COMMA- denotes ,
T6562 13512-13515 CC denotes and
T6563 13516-13524 NN denotes gelatine
T6564 13525-13535 NN denotes zymography
T6565 13537-13547 NN denotes Expression
T6566 13548-13550 IN denotes of
T6567 13551-13555 NN denotes MMP9
T6568 13556-13559 VB denotes was
T6569 13560-13568 VB denotes elevated
T6570 13569-13574 IN denotes after
T6571 13575-13582 NN denotes scratch
T6572 13583-13589 NN denotes injury
T6573 13590-13592 IN denotes in
T6574 13593-13595 NN denotes WT
T6575 13596-13599 CC denotes and
T6576 13600-13602 NN denotes KO
T6577 13603-13613 NN denotes astrocytes
T6578 13614-13616 IN denotes as
T6579 13617-13625 VB denotes compared
T6580 13626-13630 IN denotes with
T6581 13631-13636 PRP-DOLLAR- denotes their
T6582 13637-13641 NN denotes sham
T6583 13642-13654 NN denotes counterparts
T6584 13656-13659 DT denotes The
T6585 13660-13664 NN denotes mRNA
T6586 13665-13670 NN denotes level
T6587 13671-13673 IN denotes of
T6588 13674-13678 NN denotes MMP9
T6589 13679-13682 VB denotes was
T6590 13683-13689 JJ denotes higher
T6591 13690-13692 IN denotes in
T6592 13693-13698 NN denotes group
T6593 13699-13701 NN denotes KO
T6594 13702-13705 NN denotes TBI
T6595 13706-13710 IN denotes than
T6596 13711-13713 IN denotes in
T6597 13714-13719 NN denotes group
T6598 13720-13722 NN denotes WT
T6599 13723-13726 NN denotes TBI
T6600 13727-13728 -LRB- denotes (
T6601 13728-13732 CD denotes 1.36
T6602 13733-13734 SYM denotes ±
T6603 13735-13740 CD denotes 0.090
T6604 13741-13747 IN denotes versus
T6605 13748-13752 CD denotes 1.01
T6606 13753-13754 SYM denotes ±
T6607 13755-13760 CD denotes 0.068
T6608 13760-13761 -COMMA- denotes ,
T6609 13762-13763 NN denotes P
T6610 13764-13765 SYM denotes <
T6611 13766-13770 CD denotes 0.01
T6612 13770-13771 -RRB- denotes )
T6613 13772-13773 -LRB- denotes (
T6614 13773-13780 NN denotes Figures
T6615 13781-13782 CD denotes 3
T6616 13782-13783 -LRB- denotes (
T6617 13783-13784 DT denotes a
T6618 13784-13785 -RRB- denotes )
T6619 13786-13789 CC denotes and
T6620 13790-13791 CD denotes 3
T6621 13791-13792 -LRB- denotes (
T6622 13792-13793 NN denotes e
T6623 13793-13794 -RRB- denotes )
T6624 13794-13795 -RRB- denotes )
T6625 13797-13808 JJ denotes Significant
T6626 13809-13819 NN denotes difference
T6627 13820-13823 VB denotes was
T6628 13824-13828 RB denotes also
T6629 13829-13839 VB denotes discovered
T6630 13840-13842 IN denotes in
T6631 13843-13847 NN denotes MMP9
T6632 13848-13855 NN denotes protein
T6633 13856-13861 NN denotes level
T6634 13862-13864 IN denotes by
T6635 13865-13872 JJ denotes western
T6636 13873-13877 NN denotes blot
T6637 13877-13878 -COMMA- denotes ,
T6638 13879-13881 IN denotes as
T6639 13882-13886 CD denotes 1.44
T6640 13887-13888 SYM denotes ±
T6641 13889-13894 CD denotes 0.076
T6642 13895-13898 IN denotes for
T6643 13899-13904 NN denotes group
T6644 13905-13907 NN denotes KO
T6645 13908-13911 NNP denotes TBI
T6646 13912-13915 CC denotes and
T6647 13916-13920 CD denotes 1.13
T6648 13921-13922 SYM denotes ±
T6649 13923-13928 CD denotes 0.048
T6650 13929-13932 IN denotes for
T6651 13933-13938 NN denotes group
T6652 13939-13941 NN denotes WT
T6653 13942-13945 NN denotes TBI
T6654 13946-13947 -LRB- denotes (
T6655 13947-13948 NN denotes P
T6656 13949-13950 SYM denotes <
T6657 13951-13955 CD denotes 0.01
T6658 13955-13956 -RRB- denotes )
T6659 13957-13958 -LRB- denotes (
T6660 13958-13964 NN denotes Figure
T6661 13965-13966 CD denotes 5
T6662 13966-13967 -RRB- denotes )
T6663 13969-13977 NN denotes Gelatine
T6664 13978-13988 NN denotes zymography
T6665 13989-13997 VB denotes revealed
T6666 13998-14004 JJ denotes higher
T6667 14005-14009 NN denotes MMP9
T6668 14010-14018 NN denotes activity
T6669 14019-14021 IN denotes in
T6670 14022-14027 NN denotes group
T6671 14028-14030 NN denotes KO
T6672 14031-14034 NN denotes TBI
T6673 14035-14039 IN denotes than
T6674 14040-14044 DT denotes that
T6675 14045-14047 IN denotes in
T6676 14048-14053 NN denotes group
T6677 14054-14056 NNP denotes WT
T6678 14057-14060 NNP denotes TBI
T6679 14061-14064 RB denotes too
T6680 14065-14066 -LRB- denotes (
T6681 14066-14072 CD denotes 101.76
T6682 14073-14074 SYM denotes ±
T6683 14075-14080 CD denotes 6.343
T6684 14081-14087 IN denotes versus
T6685 14088-14093 CD denotes 76.32
T6686 14094-14095 SYM denotes ±
T6687 14096-14101 CD denotes 3.388
T6688 14101-14102 -COMMA- denotes ,
T6689 14103-14104 NN denotes P
T6690 14105-14106 SYM denotes <
T6691 14107-14111 CD denotes 0.01
T6692 14111-14112 -RRB- denotes )
T6693 14113-14114 -LRB- denotes (
T6694 14114-14120 NN denotes Figure
T6695 14121-14122 CD denotes 6
T6696 14122-14123 -RRB- denotes )
T7368 14140-14143 DT denotes The
T7369 14144-14151 JJ denotes present
T7370 14152-14157 NN denotes study
T7371 14158-14170 VB denotes demonstrated
T7372 14171-14175 IN denotes that
T7373 14176-14183 NN denotes scratch
T7374 14184-14190 NN denotes injury
T7375 14191-14198 VB denotes induced
T7376 14199-14202 DT denotes the
T7377 14203-14215 NN denotes upregulation
T7378 14216-14218 IN denotes of
T7379 14219-14224 NN denotes NF-κB
T7380 14225-14228 NN denotes DNA
T7381 14229-14236 NN denotes binding
T7382 14237-14245 NN denotes activity
T7383 14246-14249 CC denotes and
T7384 14250-14264 NN denotes overexpression
T7385 14265-14267 IN denotes of
T7386 14268-14273 NN denotes TNF-α
T7387 14273-14274 -COMMA- denotes ,
T7388 14275-14280 NN denotes IL-1β
T7389 14280-14281 -COMMA- denotes ,
T7390 14282-14286 NN denotes IL-6
T7391 14286-14287 -COMMA- denotes ,
T7392 14288-14291 CC denotes and
T7393 14292-14296 NN denotes MMP9
T7394 14297-14299 IN denotes in
T7395 14300-14308 VB denotes cultured
T7396 14309-14319 NN denotes astrocytes
T7397 14321-14325 RB denotes Also
T7398 14326-14328 PRP denotes we
T7399 14329-14337 VB denotes revealed
T7400 14338-14342 IN denotes that
T7401 14343-14350 NN denotes scratch
T7402 14351-14357 NN denotes injury
T7403 14358-14365 VB denotes induced
T7404 14366-14372 JJ denotes higher
T7405 14373-14381 NN denotes activity
T7406 14382-14384 IN denotes of
T7407 14385-14390 NN denotes NF-κB
T7408 14391-14394 CC denotes and
T7409 14395-14403 VB denotes enhanced
T7410 14404-14414 NN denotes expression
T7411 14415-14417 IN denotes of
T7412 14418-14433 JJ denotes proinflammatory
T7413 14434-14443 NN denotes cytokines
T7414 14444-14446 IN denotes in
T7415 14447-14451 NN denotes Nrf2
T7416 14452-14460 NN denotes knockout
T7417 14461-14469 VB denotes cultured
T7418 14470-14480 NN denotes astrocytes
T7419 14481-14485 IN denotes than
T7420 14486-14491 DT denotes those
T7421 14492-14494 IN denotes in
T7422 14495-14503 JJ denotes wildtype
T7423 14504-14514 NN denotes astrocytes
T7424 14515-14518 IN denotes for
T7425 14519-14522 DT denotes the
T7426 14523-14528 JJ denotes first
T7427 14529-14533 NN denotes time
T7428 14535-14537 PRP denotes It
T7429 14538-14541 VB denotes has
T7430 14542-14546 VB denotes been
T7431 14547-14559 VB denotes demonstrated
T7432 14560-14564 IN denotes that
T7433 14565-14570 NN denotes NF-κB
T7434 14571-14573 VB denotes is
T7435 14574-14583 VB denotes activated
T7436 14584-14586 IN denotes in
T7437 14587-14592 NN denotes brain
T7438 14593-14596 CC denotes and
T7439 14597-14603 JJ denotes spinal
T7440 14604-14608 NN denotes cord
T7441 14609-14614 IN denotes after
T7442 14615-14624 JJ denotes traumatic
T7443 14625-14631 NN denotes injury
T7444 14632-14633 -LRB- denotes [
T7445 14633-14634 CD denotes 2
T7446 14634-14635 -COMMA- denotes ,
T7447 14636-14637 CD denotes 9
T7448 14637-14638 -RRB- denotes ]
T7449 14640-14642 IN denotes As
T7450 14643-14644 DT denotes a
T7451 14645-14655 NN denotes transcript
T7452 14656-14662 NN denotes factor
T7453 14662-14663 -COMMA- denotes ,
T7454 14664-14669 NN denotes NF-κB
T7455 14670-14675 VB denotes binds
T7456 14676-14680 IN denotes with
T7457 14681-14684 NN denotes DNA
T7458 14685-14689 IN denotes once
T7459 14690-14692 PRP denotes it
T7460 14693-14696 VB denotes was
T7461 14697-14706 VB denotes activated
T7462 14707-14710 CC denotes and
T7463 14711-14718 VB denotes induces
T7464 14719-14732 NN denotes transcription
T7465 14733-14735 IN denotes of
T7466 14736-14740 NN denotes MMP9
T7467 14741-14744 CC denotes and
T7468 14745-14746 DT denotes a
T7469 14747-14754 NN denotes battery
T7470 14755-14757 IN denotes of
T7471 14758-14773 JJ denotes proinflammatory
T7472 14774-14783 NN denotes cytokines
T7473 14783-14784 -COMMA- denotes ,
T7474 14785-14794 VB denotes including
T7475 14795-14800 NN denotes TNF-α
T7476 14800-14801 -COMMA- denotes ,
T7477 14802-14807 NN denotes IL-1β
T7478 14807-14808 -COMMA- denotes ,
T7479 14809-14812 CC denotes and
T7480 14813-14817 NN denotes IL-6
T7481 14817-14818 -COMMA- denotes ,
T7482 14819-14821 IN denotes in
T7483 14822-14827 NN denotes brain
T7484 14828-14835 NN denotes tissues
T7485 14836-14841 IN denotes after
T7486 14842-14845 NNP denotes TBI
T7487 14846-14847 -LRB- denotes [
T7488 14847-14848 CD denotes 3
T7489 14848-14849 -COMMA- denotes ,
T7490 14850-14852 CD denotes 10
T7491 14852-14853 -COMMA- denotes ,
T7492 14854-14856 CD denotes 11
T7493 14856-14857 -RRB- denotes ]
T7494 14859-14862 PRP-DOLLAR- denotes Our
T7495 14863-14870 NN denotes results
T7496 14871-14875 RB denotes also
T7497 14876-14884 VB denotes revealed
T7498 14885-14889 IN denotes that
T7499 14890-14897 NN denotes scratch
T7500 14898-14904 NN denotes injury
T7501 14905-14912 VB denotes induced
T7502 14913-14922 NN denotes elevation
T7503 14923-14925 IN denotes of
T7504 14926-14931 NN denotes NF-κB
T7505 14932-14935 NN denotes DNA
T7506 14936-14943 NN denotes binding
T7507 14944-14952 NN denotes activity
T7508 14952-14953 -COMMA- denotes ,
T7509 14954-14968 NN denotes overexpression
T7510 14969-14971 IN denotes of
T7511 14972-14976 NN denotes MMP9
T7512 14976-14977 -COMMA- denotes ,
T7513 14978-14981 CC denotes and
T7514 14982-14997 JJ denotes proinflammatory
T7515 14998-15007 NN denotes mediators
T7516 15008-15017 VB denotes mentioned
T7517 15018-15023 IN denotes above
T7518 15024-15026 IN denotes in
T7519 15027-15035 VB denotes cultured
T7520 15036-15046 NN denotes astrocytes
T7521 15048-15050 PRP denotes It
T7522 15051-15054 VB denotes has
T7523 15055-15059 VB denotes been
T7524 15060-15072 VB denotes demonstrated
T7525 15073-15077 IN denotes that
T7526 15078-15083 EX denotes there
T7527 15084-15086 VB denotes is
T7528 15087-15089 DT denotes an
T7529 15090-15104 JJ denotes autoregulatory
T7530 15105-15109 NN denotes loop
T7531 15110-15115 IN denotes among
T7532 15116-15121 DT denotes these
T7533 15122-15137 JJ denotes proinflammatory
T7534 15138-15147 NN denotes mediators
T7535 15149-15152 IN denotes For
T7536 15153-15160 NN denotes example
T7537 15160-15161 -COMMA- denotes ,
T7538 15162-15167 NN denotes TNF-α
T7539 15168-15171 CC denotes and
T7540 15172-15177 NN denotes IL-1β
T7541 15178-15181 VB denotes are
T7542 15182-15188 JJ denotes potent
T7543 15189-15200 NN denotes stimulators
T7544 15201-15204 IN denotes for
T7545 15205-15209 NN denotes MMP9
T7546 15210-15212 IN denotes in
T7547 15213-15223 NN denotes astrocytes
T7548 15224-15225 -LRB- denotes [
T7549 15225-15227 CD denotes 12
T7550 15227-15228 -COMMA- denotes ,
T7551 15229-15231 CD denotes 13
T7552 15231-15232 -RRB- denotes ]
T7553 15232-15233 -COMMA- denotes ,
T7554 15234-15237 CC denotes and
T7555 15238-15242 NN denotes IL-6
T7556 15243-15250 VB denotes induces
T7557 15251-15265 NN denotes overexpression
T7558 15266-15268 IN denotes of
T7559 15269-15273 NN denotes MMP9
T7560 15274-15276 IN denotes in
T7561 15277-15282 JJ denotes human
T7562 15283-15288 NN denotes colon
T7563 15289-15298 NN denotes carcinoma
T7564 15299-15304 NN denotes cells
T7565 15305-15306 -LRB- denotes [
T7566 15306-15308 CD denotes 14
T7567 15308-15309 -RRB- denotes ]
T7568 15309-15310 -COMMA- denotes ,
T7569 15311-15314 CC denotes and
T7570 15315-15320 NN denotes TNF-α
T7571 15321-15324 CC denotes and
T7572 15325-15330 NN denotes IL-1β
T7573 15331-15335 RB denotes also
T7574 15336-15339 MD denotes can
T7575 15340-15346 VB denotes induce
T7576 15347-15357 NN denotes activation
T7577 15358-15360 IN denotes of
T7578 15361-15366 NN denotes NF-κB
T7579 15367-15368 -LRB- denotes [
T7580 15368-15370 CD denotes 15
T7581 15370-15371 -COMMA- denotes ,
T7582 15372-15374 CD denotes 16
T7583 15374-15375 -RRB- denotes ]
T7584 15377-15381 DT denotes This
T7585 15382-15396 JJ denotes autoregulatory
T7586 15397-15401 NN denotes loop
T7587 15402-15411 RB denotes extremely
T7588 15412-15422 VB denotes aggravates
T7589 15423-15426 DT denotes the
T7590 15427-15435 JJ denotes damaging
T7591 15436-15442 NN denotes effect
T7592 15443-15445 IN denotes of
T7593 15446-15458 NN denotes inflammation
T7594 15459-15462 CC denotes and
T7595 15463-15470 VB denotes induces
T7596 15471-15480 JJ denotes secondary
T7597 15481-15487 NN denotes injury
T7598 15488-15490 TO denotes to
T7599 15491-15496 NN denotes brain
T7600 15498-15500 PRP denotes It
T7601 15501-15503 VB denotes is
T7602 15504-15505 DT denotes a
T7603 15506-15510 JJ denotes good
T7604 15511-15517 NN denotes choice
T7605 15518-15521 IN denotes for
T7606 15522-15531 VB denotes targeting
T7607 15532-15534 IN denotes on
T7608 15535-15537 DT denotes an
T7609 15538-15546 JJ denotes upstream
T7610 15547-15553 NN denotes factor
T7611 15554-15556 TO denotes to
T7612 15557-15564 VB denotes prevent
T7613 15565-15569 JJ denotes such
T7614 15570-15584 JJ denotes autoregulatory
T7615 15585-15589 NN denotes loop
T7616 15590-15595 IN denotes after
T7617 15596-15599 NN denotes TBI
T7618 15601-15609 NN denotes Nrf2-ARE
T7619 15610-15617 NN denotes pathway
T7620 15618-15621 VB denotes has
T7621 15622-15626 VB denotes been
T7622 15627-15633 VB denotes proved
T7623 15634-15636 TO denotes to
T7624 15637-15639 VB denotes be
T7625 15640-15643 DT denotes the
T7626 15644-15647 JJ denotes key
T7627 15648-15657 NN denotes regulator
T7628 15658-15660 IN denotes in
T7629 15661-15669 VB denotes reducing
T7630 15670-15679 JJ denotes oxidative
T7631 15680-15686 NN denotes stress
T7632 15686-15687 -COMMA- denotes ,
T7633 15688-15700 JJ denotes inflammatory
T7634 15701-15707 NN denotes damage
T7635 15707-15708 -COMMA- denotes ,
T7636 15709-15712 CC denotes and
T7637 15713-15725 NN denotes accumulation
T7638 15726-15728 IN denotes of
T7639 15729-15734 JJ denotes toxic
T7640 15735-15746 NN denotes metabolites
T7641 15746-15747 -COMMA- denotes ,
T7642 15748-15753 WDT denotes which
T7643 15754-15757 VB denotes are
T7644 15758-15761 DT denotes all
T7645 15762-15770 VB denotes involved
T7646 15771-15773 IN denotes in
T7647 15774-15777 NNP denotes TBI
T7648 15779-15782 PRP-DOLLAR- denotes Our
T7649 15783-15791 JJ denotes previous
T7650 15792-15797 NN denotes study
T7651 15798-15801 VB denotes has
T7652 15802-15808 VB denotes proved
T7653 15809-15812 DT denotes the
T7654 15813-15825 NN denotes augmentation
T7655 15826-15828 IN denotes of
T7656 15829-15833 NN denotes Nrf2
T7657 15834-15836 IN denotes in
T7658 15837-15842 NN denotes brain
T7659 15843-15849 NN denotes tissue
T7660 15850-15855 IN denotes after
T7661 15856-15859 NNP denotes TBI
T7662 15860-15861 -LRB- denotes [
T7663 15861-15863 CD denotes 17
T7664 15863-15864 -RRB- denotes ]
T7665 15866-15874 VB denotes Enhanced
T7666 15875-15880 NN denotes level
T7667 15881-15883 IN denotes of
T7668 15884-15888 NN denotes Nrf2
T7669 15889-15898 VB denotes activates
T7670 15899-15912 NN denotes transcription
T7671 15913-15915 IN denotes of
T7672 15916-15917 DT denotes a
T7673 15918-15923 NN denotes group
T7674 15924-15926 IN denotes of
T7675 15927-15938 JJ denotes antioxidant
T7676 15939-15944 NN denotes genes
T7677 15944-15945 -COMMA- denotes ,
T7678 15946-15950 JJ denotes such
T7679 15951-15953 IN denotes as
T7680 15954-15958 NN denotes heme
T7681 15959-15970 NN denotes oxygenase-1
T7682 15971-15972 -LRB- denotes (
T7683 15972-15976 NN denotes HO-1
T7684 15976-15977 -RRB- denotes )
T7685 15978-15981 CC denotes and
T7686 15982-15985 NN denotes NAD
T7687 15986-15987 -LRB- denotes (
T7688 15987-15988 NN denotes P
T7689 15988-15989 -RRB- denotes )
T7690 15989-15990 NN denotes H
T7691 15990-15991 -COLON- denotes :
T7692 15992-15999 NN denotes quinone
T7693 16000-16016 NN denotes oxidoreductase-1
T7694 16017-16018 -LRB- denotes (
T7695 16018-16022 NN denotes NQO1
T7696 16022-16023 -RRB- denotes )
T7697 16023-16024 -COMMA- denotes ,
T7698 16025-16030 WDT denotes which
T7699 16031-16036 MD denotes would
T7700 16037-16049 RB denotes subsequently
T7701 16050-16056 VB denotes reduce
T7702 16057-16060 DT denotes the
T7703 16061-16067 NN denotes damage
T7704 16068-16070 IN denotes in
T7705 16071-16076 NN denotes brain
T7706 16077-16078 -LRB- denotes [
T7707 16078-16080 CD denotes 18
T7708 16080-16081 -RRB- denotes ]
T7709 16083-16093 NN denotes Postinjury
T7710 16094-16108 NN denotes administration
T7711 16109-16111 IN denotes of
T7712 16112-16115 NNP denotes SFN
T7713 16115-16116 -COMMA- denotes ,
T7714 16117-16119 DT denotes an
T7715 16120-16127 NN denotes inducer
T7716 16128-16130 IN denotes of
T7717 16131-16135 NN denotes Nrf2
T7718 16135-16136 -COMMA- denotes ,
T7719 16137-16150 RB denotes significantly
T7720 16151-16159 VB denotes improves
T7721 16160-16167 JJ denotes spatial
T7722 16168-16174 NN denotes memory
T7723 16175-16177 IN denotes of
T7724 16178-16181 NN denotes rat
T7725 16182-16185 CC denotes and
T7726 16186-16195 VB denotes decreases
T7727 16196-16199 DT denotes the
T7728 16200-16216 NN denotes immunoreactivity
T7729 16217-16220 IN denotes for
T7730 16221-16237 JJ denotes 4-Hydroxynonenal
T7731 16238-16239 -LRB- denotes (
T7732 16239-16244 NN denotes 4-HNE
T7733 16244-16245 -RRB- denotes )
T7734 16245-16246 -COMMA- denotes ,
T7735 16247-16248 DT denotes a
T7736 16249-16255 NN denotes marker
T7737 16256-16258 IN denotes of
T7738 16259-16264 NN denotes lipid
T7739 16265-16277 NN denotes peroxidation
T7740 16277-16278 -COMMA- denotes ,
T7741 16279-16281 IN denotes in
T7742 16282-16285 DT denotes the
T7743 16286-16292 NN denotes cortex
T7744 16293-16296 CC denotes and
T7745 16297-16300 DT denotes the
T7746 16301-16304 NN denotes CA3
T7747 16305-16313 NN denotes subfield
T7748 16314-16316 IN denotes of
T7749 16317-16328 NN denotes hippocampus
T7750 16329-16334 IN denotes after
T7751 16335-16338 NNP denotes TBI
T7752 16339-16340 -LRB- denotes [
T7753 16340-16342 CD denotes 19
T7754 16342-16343 -RRB- denotes ]
T7755 16345-16347 IN denotes On
T7756 16348-16351 DT denotes the
T7757 16352-16357 JJ denotes other
T7758 16358-16362 NN denotes hand
T7759 16362-16363 -COMMA- denotes ,
T7760 16364-16378 JJ denotes Nrf2-deficient
T7761 16379-16383 NN denotes mice
T7762 16384-16390 VB denotes appear
T7763 16391-16395 RB denotes more
T7764 16396-16407 JJ denotes susceptible
T7765 16408-16410 TO denotes to
T7766 16411-16414 NNP denotes TBI
T7767 16416-16425 NN denotes Depletion
T7768 16426-16428 IN denotes of
T7769 16429-16433 NN denotes Nrf2
T7770 16434-16441 VB denotes induces
T7771 16442-16448 JJ denotes higher
T7772 16449-16459 NN denotes expression
T7773 16460-16462 IN denotes of
T7774 16463-16478 JJ denotes proinflammatory
T7775 16479-16488 NN denotes mediators
T7776 16489-16491 IN denotes in
T7777 16492-16497 NN denotes brain
T7778 16498-16503 IN denotes after
T7779 16504-16507 NNP denotes TBI
T7780 16508-16509 -LRB- denotes [
T7781 16509-16511 CD denotes 20
T7782 16511-16512 -RRB- denotes ]
T7783 16514-16518 RB denotes Here
T7784 16518-16519 -COMMA- denotes ,
T7785 16520-16523 PRP-DOLLAR- denotes our
T7786 16524-16531 NN denotes results
T7787 16532-16540 VB denotes revealed
T7788 16541-16545 IN denotes that
T7789 16546-16560 NN denotes overexpression
T7790 16561-16563 IN denotes of
T7791 16564-16569 NN denotes TNF-α
T7792 16569-16570 -COMMA- denotes ,
T7793 16571-16576 NN denotes IL-1β
T7794 16576-16577 -COMMA- denotes ,
T7795 16578-16582 NN denotes IL-6
T7796 16582-16583 -COMMA- denotes ,
T7797 16584-16587 CC denotes and
T7798 16588-16592 NN denotes MMP9
T7799 16593-16598 IN denotes after
T7800 16599-16606 NN denotes scratch
T7801 16607-16613 NN denotes injury
T7802 16614-16617 VB denotes was
T7803 16618-16622 RB denotes more
T7804 16623-16633 VB denotes aggravated
T7805 16634-16636 IN denotes in
T7806 16637-16645 VB denotes cultured
T7807 16646-16650 NN denotes Nrf2
T7808 16651-16659 NN denotes knockout
T7809 16660-16670 NN denotes astrocytes
T7810 16671-16675 IN denotes than
T7811 16676-16678 IN denotes in
T7812 16679-16687 JJ denotes wildtype
T7813 16688-16699 NN denotes astrocyetes
T7814 16700-16703 IN denotes for
T7815 16704-16707 DT denotes the
T7816 16708-16713 JJ denotes first
T7817 16714-16718 NN denotes time
T7818 16718-16719 -COMMA- denotes ,
T7819 16720-16723 CC denotes and
T7820 16724-16738 NN denotes overexpression
T7821 16739-16741 IN denotes of
T7822 16742-16747 DT denotes these
T7823 16748-16763 JJ denotes proinflammatory
T7824 16764-16773 NN denotes mediators
T7825 16774-16777 VB denotes led
T7826 16778-16780 TO denotes to
T7827 16781-16785 JJ denotes more
T7828 16786-16796 NN denotes astrocytes
T7829 16797-16803 NN denotes deaths
T7830 16805-16809 NN denotes Data
T7831 16810-16818 VB denotes obtained
T7832 16819-16823 IN denotes from
T7833 16824-16830 JJ denotes animal
T7834 16831-16838 NN denotes studies
T7835 16839-16846 VB denotes suggest
T7836 16847-16850 DT denotes the
T7837 16851-16862 NN denotes possibility
T7838 16863-16867 IN denotes that
T7839 16868-16879 JJ denotes antioxidant
T7840 16880-16886 NN denotes effect
T7841 16887-16889 IN denotes of
T7842 16890-16894 NN denotes Nrf2
T7843 16895-16898 MD denotes may
T7844 16899-16901 VB denotes be
T7845 16902-16910 VB denotes achieved
T7846 16911-16913 IN denotes by
T7847 16914-16925 NN denotes suppression
T7848 16926-16928 IN denotes of
T7849 16929-16944 JJ denotes proinflammatory
T7850 16945-16953 NN denotes pathways
T7851 16954-16959 WDT denotes which
T7852 16960-16963 VB denotes are
T7853 16964-16972 VB denotes mediated
T7854 16973-16975 IN denotes by
T7855 16976-16981 NN denotes NF-κB
T7856 16982-16991 NN denotes signaling
T7857 16993-17007 NN denotes Administration
T7858 17008-17010 IN denotes of
T7859 17011-17014 NN denotes SFN
T7860 17015-17017 VB denotes is
T7861 17018-17023 VB denotes found
T7862 17024-17026 TO denotes to
T7863 17027-17029 VB denotes be
T7864 17030-17034 JJ denotes able
T7865 17035-17037 TO denotes to
T7866 17038-17045 VB denotes inhibit
T7867 17046-17053 NN denotes IKK/IκB
T7868 17054-17069 NN denotes phosphorylation
T7869 17070-17073 CC denotes and
T7870 17074-17077 NN denotes p65
T7871 17078-17083 NN denotes NF-κB
T7872 17084-17091 NN denotes subunit
T7873 17092-17099 JJ denotes nuclear
T7874 17100-17113 NN denotes translocation
T7875 17113-17114 -COMMA- denotes ,
T7876 17115-17127 RB denotes consequently
T7877 17128-17139 VB denotes alleviating
T7878 17140-17145 NN denotes NF-κB
T7879 17146-17155 NN denotes signaling
T7880 17156-17157 -LRB- denotes [
T7881 17157-17159 CD denotes 21
T7882 17159-17160 -RRB- denotes ]
T7883 17162-17165 CC denotes And
T7884 17166-17171 NN denotes NF-κB
T7885 17172-17182 NN denotes activation
T7886 17183-17190 VB denotes induced
T7887 17191-17193 IN denotes by
T7888 17194-17212 NN denotes lipopolysaccharide
T7889 17213-17214 -LRB- denotes (
T7890 17214-17217 NN denotes LPS
T7891 17217-17218 -RRB- denotes )
T7892 17219-17224 MD denotes could
T7893 17225-17227 VB denotes be
T7894 17228-17238 VB denotes attenuated
T7895 17239-17241 IN denotes by
T7896 17242-17249 JJ denotes diverse
T7897 17250-17254 NN denotes Nrf2
T7898 17255-17265 NN denotes activators
T7899 17265-17266 -COMMA- denotes ,
T7900 17267-17271 JJ denotes such
T7901 17272-17274 IN denotes as
T7902 17275-17278 NN denotes SFN
T7903 17279-17282 CC denotes and
T7904 17283-17291 NN denotes curcumin
T7905 17292-17293 -LRB- denotes (
T7906 17293-17296 NN denotes CUR
T7907 17296-17297 -RRB- denotes )
T7908 17298-17299 -LRB- denotes [
T7909 17299-17301 CD denotes 22
T7910 17301-17302 -RRB- denotes ]
T7911 17304-17315 RB denotes Furthermore
T7912 17315-17316 -COMMA- denotes ,
T7913 17317-17320 PRP-DOLLAR- denotes our
T7914 17321-17329 JJ denotes previous
T7915 17330-17337 NN denotes studies
T7916 17338-17346 VB denotes indicate
T7917 17347-17351 IN denotes that
T7918 17352-17361 NN denotes depletion
T7919 17362-17364 IN denotes of
T7920 17365-17369 NN denotes Nrf2
T7921 17370-17377 VB denotes induces
T7922 17378-17390 NN denotes augmentation
T7923 17391-17393 IN denotes of
T7924 17394-17399 NN denotes NF-κB
T7925 17400-17408 NN denotes activity
T7926 17409-17412 CC denotes and
T7927 17413-17425 JJ denotes inflammatory
T7928 17426-17434 NN denotes response
T7929 17435-17437 IN denotes in
T7930 17438-17442 NN denotes lung
T7931 17442-17443 -COMMA- denotes ,
T7932 17444-17449 NN denotes brain
T7933 17449-17450 -COMMA- denotes ,
T7934 17451-17454 CC denotes and
T7935 17455-17464 NN denotes intestine
T7936 17465-17470 IN denotes after
T7937 17471-17474 NNP denotes TBI
T7938 17475-17476 -LRB- denotes [
T7939 17476-17477 CD denotes 4
T7940 17477-17478 -COMMA- denotes ,
T7941 17479-17480 CD denotes 5
T7942 17480-17481 -COMMA- denotes ,
T7943 17482-17484 CD denotes 23
T7944 17484-17485 -RRB- denotes ]
T7945 17487-17494 NN denotes Results
T7946 17495-17499 IN denotes from
T7947 17500-17504 DT denotes this
T7948 17505-17510 NN denotes study
T7949 17511-17518 RB denotes further
T7950 17519-17528 VB denotes confirmed
T7951 17529-17533 JJ denotes such
T7952 17534-17546 NN denotes relationship
T7953 17547-17554 VB denotes existed
T7954 17555-17557 IN denotes in
T7955 17558-17566 VB denotes cultured
T7956 17567-17577 NN denotes astrocytes
T7957 17578-17583 IN denotes after
T7958 17584-17591 NN denotes scratch
T7959 17592-17598 NN denotes injury
T7960 17600-17608 VB denotes Enhanced
T7961 17609-17619 NN denotes activation
T7962 17620-17622 IN denotes of
T7963 17623-17628 NN denotes NF-κB
T7964 17629-17631 VB denotes is
T7965 17632-17636 RB denotes also
T7966 17637-17647 VB denotes discovered
T7967 17648-17650 IN denotes in
T7968 17651-17655 NN denotes lung
T7969 17655-17656 -COMMA- denotes ,
T7970 17657-17668 NN denotes macrophages
T7971 17668-17669 -COMMA- denotes ,
T7972 17670-17673 CC denotes and
T7973 17674-17679 NN denotes mouse
T7974 17680-17689 JJ denotes embryonic
T7975 17690-17701 NN denotes fibroblasts
T7976 17702-17704 IN denotes of
T7977 17705-17719 JJ denotes Nrf2-deficient
T7978 17720-17724 NN denotes mice
T7979 17725-17730 IN denotes after
T7980 17731-17743 JJ denotes experimental
T7981 17744-17750 NN denotes sepsis
T7982 17751-17752 -LRB- denotes [
T7983 17752-17754 CD denotes 24
T7984 17754-17755 -RRB- denotes ]
T7985 17757-17770 RB denotes Interestingly
T7986 17770-17771 -COMMA- denotes ,
T7987 17772-17774 PRP denotes it
T7988 17775-17777 VB denotes is
T7989 17778-17786 VB denotes reported
T7990 17787-17791 IN denotes that
T7991 17792-17797 NN denotes NF-κB
T7992 17798-17801 MD denotes can
T7993 17802-17809 VB denotes inhibit
T7994 17810-17814 NN denotes Nrf2
T7995 17815-17817 IN denotes at
T7996 17818-17833 JJ denotes transcriptional
T7997 17834-17839 NN denotes level
T7998 17841-17846 NN denotes NF-κB
T7999 17847-17850 NN denotes p65
T8000 17851-17858 NN denotes subunit
T8001 17859-17868 VB denotes repressed
T8002 17869-17872 DT denotes the
T8003 17873-17881 NN denotes Nrf2-ARE
T8004 17882-17889 NN denotes pathway
T8005 17890-17892 IN denotes at
T8006 17893-17908 JJ denotes transcriptional
T8007 17909-17914 NN denotes level
T8008 17915-17917 IN denotes by
T8009 17918-17929 JJ denotes competitive
T8010 17930-17941 NN denotes interaction
T8011 17942-17946 IN denotes with
T8012 17947-17950 DT denotes the
T8013 17951-17958 NN denotes CH1-KIX
T8014 17959-17965 NN denotes domain
T8015 17966-17968 IN denotes of
T8016 17969-17972 NN denotes CBP
T8017 17973-17975 CC denotes or
T8018 17976-17981 JJ denotes local
T8019 17982-17989 NN denotes histone
T8020 17990-18005 NN denotes hypoacetylation
T8021 18006-18007 -LRB- denotes [
T8022 18007-18009 CD denotes 25
T8023 18009-18010 -RRB- denotes ]
T8024 18012-18015 PDT denotes All
T8025 18016-18021 DT denotes these
T8026 18022-18030 NN denotes findings
T8027 18031-18039 VB denotes indicate
T8028 18040-18043 DT denotes the
T8029 18044-18053 JJ denotes potential
T8030 18054-18064 NN denotes complicate
T8031 18065-18074 NN denotes crosstalk
T8032 18075-18082 IN denotes between
T8033 18083-18088 NN denotes NF-κB
T8034 18089-18092 CC denotes and
T8035 18093-18097 NN denotes Nrf2
T8036 18097-18098 -COMMA- denotes ,
T8037 18099-18104 WDT denotes which
T8038 18105-18108 MD denotes may
T8039 18109-18111 VB denotes be
T8040 18112-18121 VB denotes regulated
T8041 18122-18124 IN denotes by
T8042 18125-18128 DT denotes the
T8043 18129-18137 JJ denotes upstream
T8044 18138-18155 JJ denotes mitogen-activated
T8045 18156-18163 NN denotes protein
T8046 18164-18170 NN denotes kinase
T8047 18171-18172 -LRB- denotes (
T8048 18172-18177 NN denotes MAPKs
T8049 18177-18178 -RRB- denotes )
T8050 18179-18186 NN denotes pathway
T8051 18187-18188 -LRB- denotes [
T8052 18188-18190 CD denotes 26
T8053 18190-18191 -RRB- denotes ]
T8054 18193-18195 PRP denotes It
T8055 18196-18199 VB denotes has
T8056 18200-18204 VB denotes been
T8057 18205-18214 VB denotes confirmed
T8058 18215-18219 IN denotes that
T8059 18220-18224 NN denotes Nrf2
T8060 18225-18227 VB denotes is
T8061 18228-18234 RB denotes mainly
T8062 18235-18243 VB denotes detected
T8063 18244-18246 IN denotes in
T8064 18247-18254 NN denotes nucleus
T8065 18255-18257 IN denotes of
T8066 18258-18268 NN denotes astrocytes
T8067 18269-18274 IN denotes after
T8068 18275-18278 NNP denotes TBI
T8069 18279-18280 -LRB- denotes [
T8070 18280-18282 CD denotes 18
T8071 18282-18283 -RRB- denotes ]
T8072 18285-18287 IN denotes In
T8073 18288-18292 NN denotes view
T8074 18293-18295 IN denotes of
T8075 18296-18299 DT denotes the
T8076 18300-18304 NN denotes fact
T8077 18305-18309 IN denotes that
T8078 18310-18314 NN denotes Nrf2
T8079 18315-18317 VB denotes is
T8080 18318-18319 DT denotes a
T8081 18320-18333 NN denotes transcription
T8082 18334-18340 NN denotes factor
T8083 18341-18346 WDT denotes which
T8084 18347-18353 MD denotes should
T8085 18354-18358 VB denotes take
T8086 18359-18367 NN denotes function
T8087 18368-18374 RB denotes mainly
T8088 18375-18377 IN denotes in
T8089 18378-18385 NN denotes nucleus
T8090 18385-18386 -COMMA- denotes ,
T8091 18387-18389 PRP denotes it
T8092 18390-18393 MD denotes can
T8093 18394-18396 VB denotes be
T8094 18397-18405 VB denotes reasoned
T8095 18406-18410 IN denotes that
T8096 18411-18421 NN denotes astrocytes
T8097 18422-18425 MD denotes may
T8098 18426-18428 VB denotes be
T8099 18429-18432 CD denotes one
T8100 18433-18437 NN denotes kind
T8101 18438-18440 IN denotes of
T8102 18441-18451 NN denotes respondent
T8103 18452-18457 NN denotes cells
T8104 18458-18460 IN denotes in
T8105 18461-18471 NN denotes activation
T8106 18472-18474 IN denotes of
T8107 18475-18483 NN denotes Nrf2-ARE
T8108 18484-18491 NN denotes pathway
T8109 18492-18497 IN denotes after
T8110 18498-18501 NN denotes TBI
T8111 18503-18511 JJ denotes Previous
T8112 18512-18517 NN denotes study
T8113 18518-18528 VB denotes identified
T8114 18529-18532 DT denotes the
T8115 18533-18543 NN denotes expression
T8116 18544-18546 IN denotes of
T8117 18547-18552 NN denotes TNF-α
T8118 18552-18553 -COMMA- denotes ,
T8119 18554-18559 NN denotes IL-1β
T8120 18559-18560 -COMMA- denotes ,
T8121 18561-18564 CC denotes and
T8122 18565-18569 NN denotes IL-6
T8123 18570-18572 IN denotes in
T8124 18573-18581 VB denotes cultured
T8125 18582-18592 NN denotes astrocytes
T8126 18593-18598 IN denotes after
T8127 18599-18608 NN denotes treatment
T8128 18609-18613 IN denotes with
T8129 18614-18617 NN denotes LPS
T8130 18618-18620 CC denotes or
T8131 18621-18634 NN denotes oxyhemoglobin
T8132 18635-18636 -LRB- denotes [
T8133 18636-18638 CD denotes 27
T8134 18638-18639 -COMMA- denotes ,
T8135 18640-18642 CD denotes 28
T8136 18642-18643 -RRB- denotes ]
T8137 18645-18652 DT denotes Another
T8138 18653-18658 NN denotes study
T8139 18659-18667 VB denotes revealed
T8140 18668-18672 IN denotes that
T8141 18673-18678 IN denotes after
T8142 18679-18685 JJ denotes middle
T8143 18686-18694 JJ denotes cerebral
T8144 18695-18701 NN denotes artery
T8145 18702-18711 NN denotes occlusion
T8146 18711-18712 -COMMA- denotes ,
T8147 18713-18726 JJ denotes MMP9-positive
T8148 18727-18737 NN denotes astrocytes
T8149 18738-18742 VB denotes were
T8150 18743-18751 VB denotes observed
T8151 18752-18754 IN denotes in
T8152 18755-18760 NN denotes brain
T8153 18761-18768 NN denotes tissues
T8154 18769-18771 IN denotes by
T8155 18772-18792 NN denotes immunohistochemistry
T8156 18793-18794 -LRB- denotes [
T8157 18794-18796 CD denotes 29
T8158 18796-18797 -RRB- denotes ]
T8159 18799-18804 DT denotes Those
T8160 18805-18812 NN denotes results
T8161 18813-18821 VB denotes indicate
T8162 18822-18825 DT denotes the
T8163 18826-18830 NN denotes role
T8164 18831-18833 IN denotes of
T8165 18834-18844 NN denotes astrocytes
T8166 18845-18847 IN denotes in
T8167 18848-18860 JJ denotes inflammatory
T8168 18861-18868 NN denotes process
T8169 18869-18874 IN denotes after
T8170 18875-18880 NN denotes brain
T8171 18881-18887 NN denotes injury
T8172 18889-18892 CC denotes But
T8173 18893-18897 RB denotes till
T8174 18898-18901 RB denotes now
T8175 18901-18902 -COMMA- denotes ,
T8176 18903-18908 EX denotes there
T8177 18909-18911 VB denotes is
T8178 18912-18914 DT denotes no
T8179 18915-18920 NN denotes study
T8180 18921-18928 VB denotes focused
T8181 18929-18931 IN denotes on
T8182 18932-18935 DT denotes the
T8183 18936-18948 NN denotes relationship
T8184 18949-18954 IN denotes among
T8185 18955-18965 NN denotes astrocytes
T8186 18965-18966 -COMMA- denotes ,
T8187 18967-18971 NN denotes Nrf2
T8188 18971-18972 -COMMA- denotes ,
T8189 18973-18976 CC denotes and
T8190 18977-18992 JJ denotes proinflammatory
T8191 18993-19002 NN denotes mediators
T8192 19003-19008 IN denotes after
T8193 19009-19012 NN denotes TBI
T8194 19014-19017 PRP-DOLLAR- denotes Our
T8195 19018-19025 NN denotes results
T8196 19026-19038 VB denotes demonstrated
T8197 19039-19042 DT denotes the
T8198 19043-19054 VB denotes upregulated
T8199 19055-19065 NN denotes expression
T8200 19066-19068 IN denotes of
T8201 19069-19074 NN denotes TNF-α
T8202 19074-19075 -COMMA- denotes ,
T8203 19076-19081 NN denotes IL-1β
T8204 19081-19082 -COMMA- denotes ,
T8205 19083-19087 NN denotes IL-6
T8206 19087-19088 -COMMA- denotes ,
T8207 19089-19092 CC denotes and
T8208 19093-19097 NN denotes MMP9
T8209 19098-19100 IN denotes in
T8210 19101-19105 NN denotes Nrf2
T8211 19106-19114 NN denotes knockout
T8212 19115-19125 NN denotes astrocytes
T8213 19126-19131 IN denotes after
T8214 19132-19139 NN denotes scratch
T8215 19140-19146 NN denotes injury
T8216 19147-19150 IN denotes for
T8217 19151-19154 DT denotes the
T8218 19155-19160 JJ denotes first
T8219 19161-19165 NN denotes time
T8220 19167-19169 IN denotes In
T8221 19170-19180 NN denotes conclusion
T8222 19180-19181 -COMMA- denotes ,
T8223 19182-19191 NN denotes depletion
T8224 19192-19194 IN denotes of
T8225 19195-19199 NN denotes Nrf2
T8226 19200-19207 VB denotes induced
T8227 19208-19211 DT denotes the
T8228 19212-19222 NN denotes activation
T8229 19223-19225 IN denotes of
T8230 19226-19231 NN denotes NF-κB
T8231 19232-19235 CC denotes and
T8232 19236-19239 DT denotes the
T8233 19240-19250 NN denotes expression
T8234 19251-19253 IN denotes of
T8235 19254-19259 NN denotes TNF-α
T8236 19259-19260 -COMMA- denotes ,
T8237 19261-19266 NN denotes IL-1β
T8238 19266-19267 -COMMA- denotes ,
T8239 19268-19272 NN denotes IL-6
T8240 19272-19273 -COMMA- denotes ,
T8241 19274-19277 CC denotes and
T8242 19278-19282 NN denotes MMP9
T8243 19283-19292 VB denotes resulting
T8244 19293-19295 IN denotes in
T8245 19296-19300 JJ denotes more
T8246 19301-19305 NN denotes cell
T8247 19306-19312 NN denotes deaths
T8248 19313-19315 IN denotes in
T8249 19316-19326 NN denotes astrocytes
T8250 19327-19332 IN denotes after
T8251 19333-19340 NN denotes scratch
T8252 19341-19347 NN denotes injury
T8253 19349-19354 DT denotes These
T8254 19355-19362 NN denotes results
T8255 19363-19370 VB denotes suggest
T8256 19371-19375 IN denotes that
T8257 19376-19380 NN denotes Nrf2
T8258 19381-19384 MD denotes may
T8259 19385-19387 VB denotes be
T8260 19388-19390 DT denotes an
T8261 19391-19400 JJ denotes important
T8262 19401-19407 NN denotes target
T8263 19408-19411 IN denotes for
T8264 19412-19429 JJ denotes anti-inflammatory
T8265 19430-19437 NN denotes therapy
T8266 19438-19443 IN denotes after
T8267 19444-19447 NN denotes TBI
R1000 T1259 T1256 arg1Of Kensler,Dr.
R1001 T1259 T1257 arg1Of Kensler,Thomas
R1002 T1259 T1258 arg1Of Kensler,W.
R1003 T1259 T1260 arg1Of Kensler,(
R1004 T1263 T1260 arg2Of University,(
R1005 T1263 T1261 arg1Of University,Johns
R1006 T1263 T1262 arg1Of University,Hopkins
R1007 T1263 T1264 arg1Of University,","
R1008 T1263 T1268 arg1Of University,","
R1009 T1263 T1269 arg1Of University,USA
R1010 T1265 T1264 arg2Of Baltimore,","
R1011 T1265 T1266 arg1Of Baltimore,","
R1012 T1267 T1266 arg2Of MD,","
R1013 T1270 T1260 arg3Of ),(
R1014 T1272 T1271 arg1Of astrocytes,Primary
R1015 T1272 T1273 arg1Of astrocytes,were
R1016 T1272 T1274 arg2Of astrocytes,obtained
R1017 T1274 T1273 arg2Of obtained,were
R1018 T1274 T1275 arg1Of obtained,from
R1019 T1280 T1276 arg1Of type,postnatal
R1020 T1280 T1277 arg1Of type,2-day-old
R1021 T1280 T1278 arg1Of type,Nrf2
R1022 T1280 T1279 arg1Of type,wide
R1023 T1280 T1281 arg1Of type,(
R1024 T1280 T1284 arg1Of type,and
R1025 T1282 T1281 arg2Of WT,(
R1026 T1283 T1281 arg3Of ),(
R1027 T1284 T1275 arg2Of and,from
R1028 T1287 T1286 arg2Of KO,(
R1029 T1288 T1286 arg3Of ),(
R1030 T1289 T1284 arg2Of mice,and
R1031 T1289 T1285 arg1Of mice,knockout
R1032 T1289 T1286 arg1Of mice,(
R1033 T1289 T1290 arg1Of mice,(
R1034 T1292 T1290 arg2Of mice,(
R1035 T1292 T1291 arg1Of mice,6
R1036 T1292 T1293 arg1Of mice,for
R1037 T1295 T1293 arg2Of genotype,for
R1038 T1295 T1294 arg1Of genotype,each
R1039 T1296 T1290 arg3Of ),(
R1040 T1298 T1297 arg2Of decapitation,Following
R1041 T1301 T1300 arg1Of cortices,the
R1042 T1301 T1302 arg1Of cortices,were
R1043 T1301 T1303 arg2Of cortices,dissected
R1044 T1303 T1302 arg2Of dissected,were
R1045 T1303 T1304 arg1Of dissected,out
R1046 T1303 T1306 arg1Of dissected,and
R1047 T1306 T1297 arg1Of and,Following
R1048 T1306 T1299 arg1Of and,","
R1049 T1306 T1305 arg1Of and,","
R1050 T1308 T1309 arg1Of meninges,and
R1051 T1309 T1307 arg1Of and,the
R1052 T1309 T1313 arg1Of and,were
R1053 T1309 T1314 arg2Of and,removed
R1054 T1312 T1309 arg2Of vessels,and
R1055 T1312 T1310 arg2Of vessels,associated
R1056 T1312 T1311 arg1Of vessels,blood
R1057 T1314 T1306 arg2Of removed,and
R1058 T1314 T1313 arg2Of removed,were
R1059 T1316 T1315 arg1Of tissue,The
R1060 T1316 T1317 arg1Of tissue,was
R1061 T1316 T1319 arg2Of tissue,chopped
R1062 T1316 T1337 arg1Of tissue,agitated
R1063 T1319 T1317 arg2Of chopped,was
R1064 T1319 T1318 arg1Of chopped,roughly
R1065 T1319 T1320 arg1Of chopped,with
R1066 T1319 T1336 arg1Of chopped,and
R1067 T1323 T1320 arg2Of blade,with
R1068 T1323 T1321 arg1Of blade,a
R1069 T1323 T1322 arg1Of blade,scalpel
R1070 T1323 T1324 arg1Of blade,","
R1071 T1323 T1325 arg2Of blade,incubated
R1072 T1325 T1326 arg1Of incubated,in
R1073 T1327 T1328 arg1Of 0.5,%
R1074 T1329 T1326 arg2Of trypsin,in
R1075 T1329 T1327 arg1Of trypsin,0.5
R1076 T1329 T1330 arg1Of trypsin,for
R1077 T1329 T1333 arg1Of trypsin,at
R1078 T1332 T1330 arg2Of minutes,for
R1079 T1332 T1331 arg1Of minutes,10
R1080 T1334 T1333 arg2Of 37°C,at
R1081 T1336 T1335 arg1Of and,","
R1082 T1337 T1336 arg2Of agitated,and
R1083 T1340 T1337 arg2Of minutes,agitated
R1084 T1340 T1338 arg1Of minutes,every
R1085 T1340 T1339 arg1Of minutes,few
R1086 T1342 T1341 arg2Of digestion,After
R1087 T1345 T1344 arg1Of tissue,the
R1088 T1345 T1346 arg1Of tissue,was
R1089 T1345 T1347 arg2Of tissue,rinsed
R1090 T1347 T1341 arg1Of rinsed,After
R1091 T1347 T1343 arg1Of rinsed,","
R1092 T1347 T1346 arg2Of rinsed,was
R1093 T1347 T1348 arg1Of rinsed,twice
R1094 T1347 T1349 arg1Of rinsed,in
R1095 T1350 T1349 arg2Of DMEM,in
R1096 T1350 T1351 arg1Of DMEM,with
R1097 T1352 T1353 arg1Of 10,%
R1098 T1354 T1352 arg1Of FBS,10
R1099 T1354 T1355 arg1Of FBS,","
R1100 T1354 T1356 arg2Of FBS,followed
R1101 T1354 T1371 arg1Of FBS,","
R1102 T1360 T1356 arg1Of dissociation,followed
R1103 T1360 T1357 arg2Of dissociation,by
R1104 T1360 T1358 arg1Of dissociation,a
R1105 T1360 T1359 arg1Of dissociation,mechanical
R1106 T1360 T1361 arg1Of dissociation,in
R1107 T1362 T1361 arg2Of DMEM,in
R1108 T1362 T1363 arg1Of DMEM,with
R1109 T1366 T1364 arg1Of FBS,20
R1110 T1366 T1365 arg1Of FBS,%
R1111 T1366 T1367 arg1Of FBS,and
R1112 T1367 T1363 arg2Of and,with
R1113 T1370 T1367 arg2Of penicillin,and
R1114 T1370 T1368 arg1Of penicillin,5
R1115 T1370 T1369 arg1Of penicillin,units/mL
R1116 T1371 T1351 arg2Of ",",with
R1117 T1374 T1371 arg2Of streptomycin,","
R1118 T1374 T1372 arg1Of streptomycin,5
R1119 T1374 T1373 arg1Of streptomycin,μg/mL
R1120 T1374 T1375 arg1Of streptomycin,(
R1121 T1378 T1375 arg2Of medium,(
R1122 T1378 T1376 arg1Of medium,complete
R1123 T1378 T1377 arg1Of medium,culture
R1124 T1379 T1375 arg3Of ),(
R1125 T1381 T1380 arg2Of incubation,After
R1126 T1381 T1382 arg1Of incubation,for
R1127 T1384 T1382 arg2Of h,for
R1128 T1384 T1383 arg1Of h,1
R1129 T1387 T1386 arg1Of supernatant,the
R1130 T1387 T1388 arg1Of supernatant,was
R1131 T1387 T1389 arg2Of supernatant,transferred
R1132 T1389 T1380 arg1Of transferred,After
R1133 T1389 T1385 arg1Of transferred,","
R1134 T1389 T1388 arg2Of transferred,was
R1135 T1389 T1390 arg1Of transferred,to
R1136 T1389 T1396 arg1Of transferred,(
R1137 T1389 T1401 arg1Of transferred,for
R1138 T1393 T1394 arg1Of flask,or
R1139 T1394 T1390 arg2Of or,to
R1140 T1394 T1391 arg1Of or,a
R1141 T1394 T1392 arg1Of or,new
R1142 T1395 T1394 arg2Of dish,or
R1143 T1397 T1396 arg2Of Costar,(
R1144 T1397 T1398 arg1Of Costar,","
R1145 T1397 T1399 arg1Of Costar,USA
R1146 T1400 T1396 arg3Of ),(
R1147 T1402 T1401 arg2Of depleting,for
R1148 T1406 T1402 arg2Of cells,depleting
R1149 T1406 T1403 arg1Of cells,the
R1150 T1406 T1404 arg1Of cells,residual
R1151 T1406 T1405 arg1Of cells,epithelial
R1152 T1409 T1408 arg1Of cells,the
R1153 T1409 T1410 arg1Of cells,were
R1154 T1409 T1411 arg2Of cells,cultivated
R1155 T1411 T1407 arg1Of cultivated,Then
R1156 T1411 T1410 arg2Of cultivated,were
R1157 T1411 T1412 arg1Of cultivated,at
R1158 T1413 T1412 arg2Of 37°C,at
R1159 T1413 T1414 arg1Of 37°C,with
R1160 T1415 T1416 arg1Of 5,%
R1161 T1417 T1414 arg2Of CO2,with
R1162 T1417 T1415 arg1Of CO2,5
R1163 T1422 T1419 arg1Of medium,the
R1164 T1422 T1420 arg1Of medium,complete
R1165 T1422 T1421 arg1Of medium,culture
R1166 T1422 T1423 arg1Of medium,was
R1167 T1422 T1424 arg1Of medium,half-changed
R1168 T1423 T1418 arg1Of was,And
R1169 T1423 T1425 arg1Of was,twice
R1170 T1423 T1427 arg1Of was,week
R1171 T1424 T1423 arg2Of half-changed,was
R1172 T1427 T1426 arg1Of week,a
R1173 T1428 T1429 arg2Of Astrocytes,expanded
R1174 T1428 T1435 arg1Of Astrocytes,reach
R1175 T1429 T1430 arg1Of expanded,for
R1176 T1429 T1434 modOf expanded,to
R1177 T1432 T1431 arg1Of 7,about
R1178 T1433 T1430 arg2Of days,for
R1179 T1433 T1432 arg1Of days,7
R1180 T1435 T1434 arg1Of reach,to
R1181 T1436 T1435 arg2Of confluence,reach
R1182 T1439 T1440 arg1Of flasks,or
R1183 T1440 T1438 arg1Of or,the
R1184 T1440 T1442 arg1Of or,were
R1185 T1440 T1443 arg2Of or,shaken
R1186 T1441 T1440 arg2Of dishes,or
R1187 T1443 T1437 arg1Of shaken,Then
R1188 T1443 T1442 arg2Of shaken,were
R1189 T1443 T1444 arg1Of shaken,at
R1190 T1446 T1444 arg2Of rpm,at
R1191 T1446 T1445 arg1Of rpm,150
R1192 T1446 T1447 arg1Of rpm,for
R1193 T1449 T1447 arg2Of h,for
R1194 T1449 T1448 arg1Of h,4
R1195 T1449 T1451 arg1Of h,deplete
R1196 T1451 T1447 arg3Of deplete,for
R1197 T1451 T1450 arg1Of deplete,to
R1198 T1451 T1458 arg1Of deplete,from
R1199 T1453 T1454 arg1Of microglia,and
R1200 T1454 T1451 arg2Of and,deplete
R1201 T1454 T1452 arg1Of and,the
R1202 T1456 T1455 arg1Of adherent,less
R1203 T1457 T1454 arg2Of cells,and
R1204 T1457 T1456 arg1Of cells,adherent
R1205 T1460 T1458 arg2Of cultures,from
R1206 T1460 T1459 arg1Of cultures,the
R1207 T1462 T1461 arg2Of shaking,After
R1208 T1466 T1462 arg1Of cultures,shaking
R1209 T1466 T1464 arg1Of cultures,the
R1210 T1466 T1465 arg1Of cultures,resulting
R1211 T1466 T1467 arg1Of cultures,were
R1212 T1467 T1461 arg1Of were,After
R1213 T1467 T1463 arg1Of were,","
R1214 T1469 T1467 arg2Of astrocytes,were
R1215 T1469 T1468 arg1Of astrocytes,mainly
R1216 T1469 T1470 arg1Of astrocytes,","
R1217 T1469 T1471 arg1Of astrocytes,which
R1218 T1469 T1472 arg1Of astrocytes,were
R1219 T1469 T1473 arg2Of astrocytes,determined
R1220 T1473 T1472 arg2Of determined,were
R1221 T1473 T1474 arg1Of determined,by
R1222 T1475 T1474 arg2Of immunoreactivity,by
R1223 T1475 T1476 arg1Of immunoreactivity,for
R1224 T1477 T1476 arg2Of GFAP,for
R1225 T1477 T1478 arg1Of GFAP,(
R1226 T1479 T1480 arg1Of sc-166481,","
R1227 T1479 T1484 arg1Of sc-166481,","
R1228 T1483 T1480 arg2Of Biotechnology,","
R1229 T1483 T1481 arg1Of Biotechnology,Santa
R1230 T1483 T1482 arg1Of Biotechnology,Cruz
R1231 T1484 T1478 arg2Of ",",(
R1232 T1485 T1484 arg2Of CA,","
R1233 T1485 T1486 arg1Of CA,","
R1234 T1487 T1486 arg2Of USA,","
R1235 T1488 T1478 arg3Of ),(
R1236 T1489 T1490 arg2Of Cells,passaged
R1237 T1489 T1494 arg1Of Cells,were
R1238 T1489 T1495 arg2Of Cells,used
R1239 T1490 T1491 arg1Of passaged,for
R1240 T1493 T1491 arg2Of generations,for
R1241 T1493 T1492 arg1Of generations,2-3
R1242 T1495 T1494 arg2Of used,were
R1243 T1495 T1496 arg1Of used,in
R1244 T1499 T1496 arg2Of studies,in
R1245 T1499 T1497 arg1Of studies,the
R1246 T1499 T1498 arg1Of studies,following
R1526 T1824 T1822 arg2Of Model,In
R1527 T1824 T1823 arg1Of Model,Vitro
R1528 T1824 T1825 arg1Of Model,of
R1529 T1824 T1827 arg2Of Model,Established
R1530 T1826 T1825 arg2Of TBI,of
R1531 T1830 T1827 arg1Of Injury,Established
R1532 T1830 T1828 arg2Of Injury,by
R1533 T1830 T1829 arg1Of Injury,Scratch
R1534 T1833 T1831 arg1Of injury,Astrocyte
R1535 T1833 T1832 arg1Of injury,scratch
R1536 T1833 T1834 arg1Of injury,was
R1537 T1833 T1835 arg2Of injury,performed
R1538 T1835 T1834 arg2Of performed,was
R1539 T1835 T1837 arg1Of performed,in
R1540 T1835 T1841 arg1Of performed,[
R1541 T1837 T1836 arg1Of in,as
R1542 T1840 T1837 arg2Of report,in
R1543 T1840 T1838 arg1Of report,a
R1544 T1840 T1839 arg1Of report,previous
R1545 T1842 T1841 arg2Of 7,[
R1546 T1843 T1841 arg3Of ],[
R1547 T1844 T1845 arg1Of Astrocytes,were
R1548 T1844 T1846 arg2Of Astrocytes,planted
R1549 T1844 T1851 arg2Of Astrocytes,grown
R1550 T1846 T1847 arg1Of planted,in
R1551 T1846 T1850 arg1Of planted,and
R1552 T1849 T1847 arg2Of plates,in
R1553 T1849 T1848 arg1Of plates,6-well
R1554 T1850 T1845 arg2Of and,were
R1555 T1850 T1852 modOf and,to
R1556 T1851 T1850 arg2Of grown,and
R1557 T1853 T1852 arg1Of confluence,to
R1558 T1856 T1854 arg1Of monolayer,The
R1559 T1856 T1855 arg1Of monolayer,cell
R1560 T1856 T1857 arg1Of monolayer,was
R1561 T1856 T1858 arg2Of monolayer,scratched
R1562 T1858 T1857 arg2Of scratched,was
R1563 T1858 T1859 arg1Of scratched,with
R1564 T1858 T1865 arg1Of scratched,","
R1565 T1858 T1866 modOf scratched,resulting
R1566 T1864 T1859 arg2Of needle,with
R1567 T1864 T1860 arg1Of needle,a
R1568 T1864 T1861 arg1Of needle,sterile
R1569 T1864 T1862 arg1Of needle,26G
R1570 T1864 T1863 arg1Of needle,syringe
R1571 T1866 T1867 arg1Of resulting,in
R1572 T1869 T1867 arg2Of formation,in
R1573 T1869 T1868 arg1Of formation,the
R1574 T1869 T1870 arg1Of formation,of
R1575 T1875 T1870 arg2Of gap,of
R1576 T1875 T1871 arg1Of gap,a
R1577 T1875 T1872 arg1Of gap,0.5
R1578 T1875 T1873 arg1Of gap,mm
R1579 T1875 T1874 arg1Of gap,wide
R1580 T1877 T1876 arg1Of after,Immediately
R1581 T1878 T1877 arg2Of scratch,after
R1582 T1880 T1881 arg1Of cells,were
R1583 T1880 T1882 arg2Of cells,washed
R1584 T1880 T1895 arg2Of cells,named
R1585 T1882 T1883 arg1Of washed,twice
R1586 T1882 T1884 arg1Of washed,with
R1587 T1882 T1894 arg1Of washed,and
R1588 T1886 T1884 arg2Of PBS,with
R1589 T1886 T1885 arg1Of PBS,sterile
R1590 T1886 T1887 arg1Of PBS,","
R1591 T1886 T1888 arg2Of PBS,cultured
R1592 T1888 T1889 arg1Of cultured,with
R1593 T1892 T1889 arg2Of medium,with
R1594 T1892 T1890 arg1Of medium,complete
R1595 T1892 T1891 arg1Of medium,culture
R1596 T1894 T1877 arg1Of and,after
R1597 T1894 T1879 arg1Of and,","
R1598 T1894 T1881 arg2Of and,were
R1599 T1894 T1893 arg1Of and,","
R1600 T1895 T1894 arg2Of named,and
R1601 T1895 T1896 arg1Of named,as
R1602 T1898 T1896 arg2Of group,as
R1603 T1898 T1897 arg1Of group,TBI
R1604 T1899 T1900 arg1Of Cells,","
R1605 T1899 T1901 arg1Of Cells,which
R1606 T1899 T1902 arg1Of Cells,did
R1607 T1899 T1907 arg1Of Cells,were
R1608 T1899 T1908 arg2Of Cells,used
R1609 T1899 T1913 arg2Of Cells,named
R1610 T1902 T1903 arg1Of did,not
R1611 T1905 T1902 arg2Of scratch,did
R1612 T1905 T1904 arg2Of scratch,received
R1613 T1908 T1909 arg1Of used,as
R1614 T1908 T1912 arg1Of used,and
R1615 T1911 T1909 arg2Of control,as
R1616 T1911 T1910 arg1Of control,blank
R1617 T1912 T1906 arg1Of and,","
R1618 T1912 T1907 arg2Of and,were
R1619 T1913 T1912 arg2Of named,and
R1620 T1913 T1914 arg1Of named,as
R1621 T1916 T1914 arg2Of group,as
R1622 T1916 T1915 arg1Of group,sham
R1726 T2050 T2048 arg1Of Measurement,Cell
R1727 T2050 T2049 arg1Of Measurement,Death
R1728 T2050 T2051 arg1Of Measurement,by
R1729 T2053 T2051 arg2Of Assay,by
R1730 T2053 T2052 arg1Of Assay,CCK-8
R1731 T2057 T2054 arg1Of cells,1
R1732 T2057 T2055 arg1Of cells,×
R1733 T2057 T2056 arg1Of cells,103/well
R1734 T2057 T2058 arg1Of cells,were
R1735 T2057 T2059 arg2Of cells,seeded
R1736 T2057 T2065 arg2Of cells,cultivated
R1737 T2059 T2060 arg1Of seeded,to
R1738 T2059 T2064 arg1Of seeded,and
R1739 T2063 T2060 arg2Of plates,to
R1740 T2063 T2061 arg1Of plates,96-well
R1741 T2063 T2062 arg1Of plates,culture
R1742 T2064 T2058 arg2Of and,were
R1743 T2065 T2064 arg2Of cultivated,and
R1744 T2065 T2066 arg1Of cultivated,for
R1745 T2068 T2066 arg2Of h,for
R1746 T2068 T2067 arg1Of h,24
R1747 T2068 T2070 arg1Of h,adhere
R1748 T2070 T2066 arg3Of adhere,for
R1749 T2070 T2069 arg1Of adhere,to
R1750 T2073 T2072 arg1Of cell,the
R1751 T2073 T2074 arg1Of cell,was
R1752 T2073 T2075 arg2Of cell,scrated
R1753 T2075 T2071 arg1Of scrated,Then
R1754 T2075 T2074 arg2Of scrated,was
R1755 T2075 T2076 arg1Of scrated,as
R1756 T2077 T2076 arg2Of mentioned,as
R1757 T2077 T2078 arg1Of mentioned,above
R1758 T2081 T2079 arg1Of death,Astrocyte
R1759 T2081 T2080 arg1Of death,cell
R1760 T2081 T2082 arg1Of death,was
R1761 T2081 T2083 arg2Of death,assessed
R1762 T2083 T2082 arg2Of assessed,was
R1763 T2083 T2091 arg1Of assessed,(
R1764 T2083 T2101 arg1Of assessed,according
R1765 T2087 T2083 arg1Of kit-8,assessed
R1766 T2087 T2084 arg2Of kit-8,by
R1767 T2087 T2085 arg1Of kit-8,cell
R1768 T2087 T2086 arg1Of kit-8,counting
R1769 T2087 T2088 arg1Of kit-8,(
R1770 T2089 T2088 arg2Of CCK-8,(
R1771 T2090 T2088 arg3Of ),(
R1772 T2092 T2091 arg2Of Dojindo,(
R1773 T2092 T2093 arg1Of Dojindo,","
R1774 T2094 T2093 arg2Of Japan,","
R1775 T2095 T2091 arg3Of ),(
R1776 T2098 T2096 arg1Of h,assay
R1777 T2098 T2097 arg1Of h,24
R1778 T2098 T2099 arg1Of h,after
R1779 T2100 T2099 arg2Of scratch,after
R1780 T2101 T2098 arg1Of according,h
R1781 T2102 T2101 arg2Of to,according
R1782 T2104 T2103 arg1Of manufacturer,the
R1783 T2104 T2105 arg2Of manufacturer,'s
R1784 T2106 T2102 arg2Of protocol,to
R1785 T2106 T2105 arg1Of protocol,'s
R1786 T2107 T2108 arg1Of Briefly,","
R1787 T2107 T2112 arg1Of Briefly,was
R1788 T2107 T2113 arg2Of Briefly,added
R1789 T2107 T2118 arg2Of Briefly,incubated
R1790 T2111 T2108 arg2Of CCK-8,","
R1791 T2111 T2109 arg1Of CCK-8,10
R1792 T2111 T2110 arg1Of CCK-8,μL
R1793 T2113 T2114 arg1Of added,into
R1794 T2113 T2117 arg1Of added,and
R1795 T2116 T2114 arg2Of well,into
R1796 T2116 T2115 arg1Of well,every
R1797 T2117 T2112 arg2Of and,was
R1798 T2118 T2117 arg2Of incubated,and
R1799 T2118 T2119 arg1Of incubated,for
R1800 T2121 T2119 arg2Of h,for
R1801 T2121 T2120 arg1Of h,1
R1802 T2124 T2123 arg1Of value,OD
R1803 T2124 T2125 arg1Of value,was
R1804 T2124 T2126 arg2Of value,read
R1805 T2124 T2130 arg1Of value,using
R1806 T2126 T2122 arg1Of read,Then
R1807 T2126 T2125 arg2Of read,was
R1808 T2126 T2127 arg1Of read,at
R1809 T2126 T2130 modOf read,using
R1810 T2129 T2127 arg2Of nm,at
R1811 T2129 T2128 arg1Of nm,450
R1812 T2130 T2136 arg1Of using,(
R1813 T2135 T2130 arg2Of reader,using
R1814 T2135 T2131 arg1Of reader,a
R1815 T2135 T2132 arg1Of reader,Bio-Rad
R1816 T2135 T2133 arg1Of reader,ELISA
R1817 T2135 T2134 arg1Of reader,microplate
R1818 T2138 T2136 arg2Of Laboratories,(
R1819 T2138 T2137 arg1Of Laboratories,Bio-Rad
R1820 T2138 T2139 arg1Of Laboratories,","
R1821 T2140 T2139 arg2Of CA,","
R1822 T2140 T2141 arg1Of CA,","
R1823 T2142 T2141 arg2Of USA,","
R1824 T2143 T2136 arg3Of ),(
R1825 T2145 T2144 arg1Of measurements,All
R1826 T2145 T2146 arg1Of measurements,were
R1827 T2145 T2147 arg2Of measurements,performed
R1828 T2147 T2146 arg2Of performed,were
R1829 T2147 T2148 arg1Of performed,in
R1830 T2149 T2148 arg2Of sextuplicate,in
R1831 T2150 T2151 arg1Of Results,were
R1832 T2150 T2152 arg2Of Results,expressed
R1833 T2152 T2151 arg2Of expressed,were
R1834 T2152 T2153 arg1Of expressed,as
R1835 T2152 T2158 arg1Of expressed,at
R1836 T2154 T2153 arg2Of mean,as
R1837 T2154 T2155 arg1Of mean,of
R1838 T2157 T2155 arg2Of value,of
R1839 T2157 T2156 arg1Of value,OD
R1840 T2159 T2160 arg1Of 450,nm
R1841 T2162 T2158 arg2Of SD,at
R1842 T2162 T2159 arg1Of SD,450
R1843 T2162 T2161 arg1Of SD,±
R1968 T2327 T2324 arg1Of Assay,Electrophoretic
R1969 T2327 T2325 arg1Of Assay,Mobility
R1970 T2327 T2326 arg1Of Assay,Shift
R1971 T2327 T2328 arg1Of Assay,(
R1972 T2329 T2328 arg2Of EMSA,(
R1973 T2330 T2328 arg3Of ),(
R1974 T2331 T2332 arg1Of Monolayers,of
R1975 T2331 T2334 arg1Of Monolayers,were
R1976 T2331 T2335 arg2Of Monolayers,washed
R1977 T2331 T2339 arg2Of Monolayers,harvested
R1978 T2333 T2332 arg2Of astrocytes,of
R1979 T2335 T2336 arg1Of washed,with
R1980 T2335 T2338 arg1Of washed,and
R1981 T2337 T2336 arg2Of PBS,with
R1982 T2338 T2334 arg2Of and,were
R1983 T2339 T2338 arg2Of harvested,and
R1984 T2339 T2340 arg1Of harvested,by
R1985 T2341 T2340 arg2Of scraping,by
R1986 T2341 T2342 arg1Of scraping,into
R1987 T2344 T2342 arg2Of PBS,into
R1988 T2344 T2343 arg1Of PBS,cold
R1989 T2347 T2345 arg1Of pellet,The
R1990 T2347 T2346 arg1Of pellet,cell
R1991 T2347 T2348 arg2Of pellet,obtained
R1992 T2347 T2351 arg1Of pellet,was
R1993 T2347 T2352 arg2Of pellet,resuspended
R1994 T2350 T2348 arg1Of centrifugation,obtained
R1995 T2350 T2349 arg2Of centrifugation,by
R1996 T2352 T2351 arg2Of resuspended,was
R1997 T2352 T2353 arg1Of resuspended,in
R1998 T2354 T2355 arg1Of buffer,containing
R1999 T2354 T2367 arg1Of buffer,","
R2000 T2356 T2357 arg1Of 10,mM
R2001 T2358 T2356 arg1Of HEPES,10
R2002 T2358 T2359 arg1Of HEPES,(
R2003 T2358 T2363 arg1Of HEPES,","
R2004 T2360 T2359 arg2Of pH,(
R2005 T2360 T2361 arg1Of pH,7.9
R2006 T2362 T2359 arg3Of ),(
R2007 T2363 T2355 arg2Of ",",containing
R2008 T2364 T2365 arg1Of 10,mM
R2009 T2366 T2363 arg2Of KCl,","
R2010 T2366 T2364 arg1Of KCl,10
R2011 T2367 T2353 arg2Of ",",in
R2012 T2368 T2369 arg1Of 0.1,mM
R2013 T2370 T2368 arg1Of EDTA,0.1
R2014 T2370 T2371 arg1Of EDTA,","
R2015 T2371 T2375 arg1Of ",",","
R2016 T2372 T2373 arg1Of 0.1,mM
R2017 T2374 T2371 arg2Of EGTA,","
R2018 T2374 T2372 arg1Of EGTA,0.1
R2019 T2375 T2380 arg1Of ",",and
R2020 T2376 T2377 arg1Of 1.0,mM
R2021 T2378 T2375 arg2Of DTT,","
R2022 T2378 T2376 arg1Of DTT,1.0
R2023 T2380 T2367 arg2Of and,","
R2024 T2380 T2379 arg1Of and,","
R2025 T2381 T2382 arg1Of 0.5,mM
R2026 T2384 T2380 arg2Of fluoride,and
R2027 T2384 T2381 arg1Of fluoride,0.5
R2028 T2384 T2383 arg1Of fluoride,phenylmethylsulfonyl
R2029 T2386 T2385 arg1Of 10,Then
R2030 T2386 T2387 arg1Of 10,%
R2031 T2389 T2386 arg1Of P-40,10
R2032 T2389 T2388 arg1Of P-40,Nonidet
R2033 T2389 T2390 arg1Of P-40,was
R2034 T2389 T2391 arg2Of P-40,added
R2035 T2389 T2393 arg2Of P-40,vortexed
R2036 T2391 T2392 arg1Of added,and
R2037 T2392 T2390 arg2Of and,was
R2038 T2392 T2396 arg1Of and,and
R2039 T2393 T2392 arg2Of vortexed,and
R2040 T2394 T2393 arg3Of briefly,vortexed
R2041 T2396 T2395 arg1Of and,","
R2042 T2398 T2397 arg1Of nuclei,the
R2043 T2398 T2399 arg1Of nuclei,were
R2044 T2398 T2400 arg2Of nuclei,pelleted
R2045 T2400 T2396 arg2Of pelleted,and
R2046 T2400 T2399 arg2Of pelleted,were
R2047 T2402 T2400 arg1Of centrifugation,pelleted
R2048 T2402 T2401 arg2Of centrifugation,by
R2049 T2405 T2403 arg1Of proteins,The
R2050 T2405 T2404 arg1Of proteins,nuclear
R2051 T2405 T2406 arg1Of proteins,were
R2052 T2405 T2407 arg2Of proteins,extracted
R2053 T2407 T2406 arg2Of extracted,were
R2054 T2407 T2408 arg1Of extracted,with
R2055 T2409 T2410 arg1Of buffer,containing
R2056 T2409 T2422 arg1Of buffer,","
R2057 T2411 T2412 arg1Of 20,mM
R2058 T2413 T2411 arg1Of HEPES,20
R2059 T2413 T2414 arg1Of HEPES,(
R2060 T2413 T2418 arg1Of HEPES,","
R2061 T2415 T2414 arg2Of pH,(
R2062 T2415 T2416 arg1Of pH,7.9
R2063 T2417 T2414 arg3Of ),(
R2064 T2418 T2410 arg2Of ",",containing
R2065 T2419 T2420 arg1Of 0.4,mM
R2066 T2421 T2418 arg2Of NaCl,","
R2067 T2421 T2419 arg1Of NaCl,0.4
R2068 T2422 T2408 arg2Of ",",with
R2069 T2423 T2424 arg1Of 1.0,mM
R2070 T2425 T2423 arg1Of EDTA,1.0
R2071 T2425 T2426 arg1Of EDTA,","
R2072 T2426 T2430 arg1Of ",",","
R2073 T2427 T2428 arg1Of 1.0,mM
R2074 T2429 T2426 arg2Of EGTA,","
R2075 T2429 T2427 arg1Of EGTA,1.0
R2076 T2430 T2435 arg1Of ",",and
R2077 T2431 T2432 arg1Of 1.0,mM
R2078 T2433 T2430 arg2Of DTT,","
R2079 T2433 T2431 arg1Of DTT,1.0
R2080 T2435 T2422 arg2Of and,","
R2081 T2435 T2434 arg1Of and,","
R2082 T2436 T2437 arg1Of 1.0,mM
R2083 T2439 T2435 arg2Of fluoride,and
R2084 T2439 T2436 arg1Of fluoride,1.0
R2085 T2439 T2438 arg1Of fluoride,phenylmethylsulfonyl
R2086 T2441 T2440 arg1Of material,Insoluble
R2087 T2441 T2442 arg1Of material,was
R2088 T2441 T2443 arg2Of material,removed
R2089 T2443 T2442 arg2Of removed,was
R2090 T2443 T2446 arg1Of removed,at
R2091 T2443 T2450 arg1Of removed,and
R2092 T2445 T2443 arg1Of centrifugation,removed
R2093 T2445 T2444 arg2Of centrifugation,by
R2094 T2448 T2446 arg2Of rpm,at
R2095 T2448 T2447 arg1Of rpm,14000
R2096 T2450 T2449 arg1Of and,","
R2097 T2452 T2451 arg1Of supernatant,the
R2098 T2452 T2453 arg1Of supernatant,containing
R2099 T2452 T2457 arg1Of supernatant,was
R2100 T2452 T2458 arg2Of supernatant,stored
R2101 T2456 T2453 arg2Of proteins,containing
R2102 T2456 T2454 arg1Of proteins,the
R2103 T2456 T2455 arg1Of proteins,nuclear
R2104 T2458 T2450 arg2Of stored,and
R2105 T2458 T2457 arg2Of stored,was
R2106 T2458 T2459 arg1Of stored,at
R2107 T2458 T2461 arg1Of stored,until
R2108 T2460 T2459 arg2Of –80°C,at
R2109 T2462 T2461 arg2Of use,until
R2110 T2464 T2463 arg1Of concentration,Protein
R2111 T2464 T2465 arg1Of concentration,was
R2112 T2464 T2466 arg2Of concentration,determined
R2113 T2466 T2465 arg2Of determined,was
R2114 T2467 T2466 arg3Of using,determined
R2115 T2467 T2473 arg1Of using,with
R2116 T2472 T2467 arg2Of kit,using
R2117 T2472 T2468 arg1Of kit,a
R2118 T2472 T2469 arg1Of kit,bicinchoninic
R2119 T2472 T2470 arg1Of kit,acid
R2120 T2472 T2471 arg1Of kit,assay
R2121 T2476 T2473 arg2Of albumin,with
R2122 T2476 T2474 arg1Of albumin,bovine
R2123 T2476 T2475 arg1Of albumin,serum
R2124 T2476 T2477 arg1Of albumin,as
R2125 T2482 T2481 arg1Of Biochemicals,Pierce
R2126 T2482 T2483 arg1Of Biochemicals,","
R2127 T2483 T2485 arg1Of ",",","
R2128 T2484 T2483 arg2Of Rockford,","
R2129 T2485 T2477 arg2Of ",",as
R2130 T2485 T2478 arg1Of ",",the
R2131 T2485 T2479 arg1Of ",",standard
R2132 T2485 T2480 arg2Of ",",(
R2133 T2485 T2487 arg1Of ",",","
R2134 T2485 T2488 arg1Of ",",USA
R2135 T2486 T2485 arg2Of IL,","
R2136 T2489 T2480 arg3Of ),(
R2137 T2490 T2491 arg1Of EMSA,was
R2138 T2490 T2492 arg2Of EMSA,performed
R2139 T2492 T2491 arg2Of performed,was
R2140 T2493 T2492 arg3Of using,performed
R2141 T2497 T2493 arg2Of system,using
R2142 T2497 T2494 arg1Of system,gel
R2143 T2497 T2495 arg1Of system,shift
R2144 T2497 T2496 arg1Of system,assay
R2145 T2497 T2498 arg1Of system,(
R2146 T2499 T2500 arg1Of Promega,","
R2147 T2500 T2502 arg1Of ",",","
R2148 T2501 T2500 arg2Of Madison,","
R2149 T2502 T2498 arg2Of ",",(
R2150 T2502 T2504 arg1Of ",",","
R2151 T2502 T2505 arg1Of ",",USA
R2152 T2503 T2502 arg2Of WI,","
R2153 T2506 T2498 arg3Of ),(
R2154 T2509 T2507 arg1Of probe,Consensus
R2155 T2509 T2508 arg1Of probe,oligonucleotide
R2156 T2509 T2510 arg1Of probe,(
R2157 T2509 T2514 arg1Of probe,was
R2158 T2509 T2515 arg2Of probe,end-labeled
R2159 T2509 T2519 arg1Of probe,using
R2160 T2511 T2510 arg2Of 5′-AGTTGAGGGGACTTTCCCAGGG-3,(
R2161 T2511 T2512 arg1Of 5′-AGTTGAGGGGACTTTCCCAGGG-3,′
R2162 T2513 T2510 arg3Of ),(
R2163 T2515 T2514 arg2Of end-labeled,was
R2164 T2515 T2519 modOf end-labeled,using
R2165 T2518 T2515 arg1Of kinase,end-labeled
R2166 T2518 T2516 arg2Of kinase,by
R2167 T2518 T2517 arg1Of kinase,T4-polynucleotide
R2168 T2521 T2520 arg2Of γ-32P,[
R2169 T2522 T2520 arg3Of ],[
R2170 T2523 T2519 arg2Of -ATP,using
R2171 T2523 T2520 arg1Of -ATP,[
R2172 T2523 T2524 arg1Of -ATP,(
R2173 T2526 T2524 arg2Of Biotech.,(
R2174 T2526 T2525 arg1Of Biotech.,Free
R2175 T2526 T2527 arg1Of Biotech.,","
R2176 T2528 T2527 arg2Of Beijing,","
R2177 T2528 T2529 arg1Of Beijing,","
R2178 T2530 T2529 arg2Of China,","
R2179 T2531 T2524 arg3Of ),(
R2180 T2533 T2532 arg1Of protein,Nuclear
R2181 T2533 T2534 arg1Of protein,(
R2182 T2533 T2538 arg1Of protein,was
R2183 T2533 T2539 arg2Of protein,preincubated
R2184 T2536 T2534 arg2Of μg,(
R2185 T2536 T2535 arg1Of μg,20
R2186 T2537 T2534 arg3Of ),(
R2187 T2539 T2538 arg2Of preincubated,was
R2188 T2539 T2540 arg1Of preincubated,in
R2189 T2544 T2540 arg2Of buffer,in
R2190 T2544 T2541 arg1Of buffer,20
R2191 T2544 T2542 arg1Of buffer,μL
R2192 T2544 T2543 arg1Of buffer,binding
R2193 T2544 T2545 arg1Of buffer,containing
R2194 T2546 T2547 arg1Of 10,mM
R2195 T2548 T2546 arg1Of Tris-HCl,10
R2196 T2548 T2549 arg1Of Tris-HCl,(
R2197 T2548 T2553 arg1Of Tris-HCl,","
R2198 T2550 T2549 arg2Of PH,(
R2199 T2550 T2551 arg1Of PH,7.5
R2200 T2552 T2549 arg3Of ),(
R2201 T2553 T2557 arg1Of ",",","
R2202 T2554 T2555 arg1Of 1,mM
R2203 T2556 T2553 arg2Of MgCl2,","
R2204 T2556 T2554 arg1Of MgCl2,1
R2205 T2557 T2561 arg1Of ",",","
R2206 T2558 T2559 arg1Of 0.5,mM
R2207 T2560 T2557 arg2Of NaCl,","
R2208 T2560 T2558 arg1Of NaCl,0.5
R2209 T2561 T2545 arg2Of ",",containing
R2210 T2562 T2563 arg1Of 4,%
R2211 T2564 T2562 arg1Of glycerol,4
R2212 T2564 T2565 arg1Of glycerol,","
R2213 T2565 T2569 arg1Of ",",","
R2214 T2566 T2567 arg1Of 0.5,mM
R2215 T2568 T2565 arg2Of EDTA,","
R2216 T2568 T2566 arg1Of EDTA,0.5
R2217 T2569 T2574 arg1Of ",",and
R2218 T2570 T2571 arg1Of 0.5,mM
R2219 T2572 T2569 arg2Of DTT,","
R2220 T2572 T2570 arg1Of DTT,0.5
R2221 T2574 T2561 arg2Of and,","
R2222 T2574 T2573 arg1Of and,","
R2223 T2578 T2574 arg2Of dI-dC,and
R2224 T2578 T2575 arg1Of dI-dC,2
R2225 T2578 T2576 arg1Of dI-dC,μg
R2226 T2578 T2577 arg1Of dI-dC,poly
R2227 T2578 T2579 arg1Of dI-dC,for
R2228 T2581 T2579 arg2Of minutes,for
R2229 T2581 T2580 arg1Of minutes,20
R2230 T2581 T2582 arg1Of minutes,on
R2231 T2583 T2582 arg2Of ice,on
R2232 T2585 T2584 arg2Of addition,After
R2233 T2585 T2586 arg1Of addition,of
R2234 T2592 T2586 arg2Of probe,of
R2235 T2592 T2587 arg1Of probe,the
R2236 T2592 T2588 arg1Of probe,1
R2237 T2592 T2589 arg1Of probe,μL
R2238 T2592 T2590 arg1Of probe,32P-labled
R2239 T2592 T2591 arg1Of probe,oligonucleotide
R2240 T2595 T2594 arg1Of incubation,the
R2241 T2595 T2596 arg1Of incubation,was
R2242 T2595 T2597 arg2Of incubation,continued
R2243 T2597 T2584 arg1Of continued,After
R2244 T2597 T2593 arg1Of continued,","
R2245 T2597 T2596 arg2Of continued,was
R2246 T2597 T2598 arg1Of continued,for
R2247 T2600 T2598 arg2Of minutes,for
R2248 T2600 T2599 arg1Of minutes,20
R2249 T2600 T2601 arg1Of minutes,on
R2250 T2602 T2601 arg2Of ice,on
R2251 T2605 T2603 arg1Of complexes,The
R2252 T2605 T2604 arg1Of complexes,DNA-protein
R2253 T2605 T2606 arg1Of complexes,were
R2254 T2605 T2607 arg2Of complexes,separated
R2255 T2607 T2606 arg2Of separated,were
R2256 T2607 T2610 arg1Of separated,on
R2257 T2607 T2616 arg1Of separated,in
R2258 T2609 T2607 arg1Of electrophoresis,separated
R2259 T2609 T2608 arg2Of electrophoresis,by
R2260 T2611 T2612 arg1Of 4,%
R2261 T2615 T2610 arg2Of gel,on
R2262 T2615 T2611 arg1Of gel,4
R2263 T2615 T2613 arg1Of gel,nondenaturing
R2264 T2615 T2614 arg1Of gel,polyacrylamide
R2265 T2620 T2616 arg2Of buffer,in
R2266 T2620 T2617 arg1Of buffer,0.5
R2267 T2620 T2618 arg1Of buffer,×
R2268 T2620 T2619 arg1Of buffer,TBE
R2269 T2620 T2621 arg1Of buffer,(
R2270 T2620 T2624 arg1Of buffer,at
R2271 T2622 T2621 arg2Of tris-borate-EDTA,(
R2272 T2623 T2621 arg3Of ),(
R2273 T2626 T2624 arg2Of V,at
R2274 T2626 T2625 arg1Of V,390
R2275 T2626 T2627 arg1Of V,for
R2276 T2629 T2627 arg2Of hour,for
R2277 T2629 T2628 arg1Of hour,1
R2278 T2629 T2630 arg1Of hour,at
R2279 T2631 T2630 arg2Of 4°C,at
R2280 T2633 T2632 arg2Of electrophoresis,After
R2281 T2636 T2635 arg1Of gel,the
R2282 T2636 T2637 arg1Of gel,was
R2283 T2636 T2638 arg2Of gel,dried
R2284 T2636 T2640 arg2Of gel,exposed
R2285 T2638 T2639 arg1Of dried,and
R2286 T2639 T2632 arg1Of and,After
R2287 T2639 T2634 arg1Of and,","
R2288 T2639 T2637 arg2Of and,was
R2289 T2640 T2639 arg2Of exposed,and
R2290 T2640 T2641 arg1Of exposed,to
R2291 T2643 T2641 arg2Of film,to
R2292 T2643 T2642 arg1Of film,X-ray
R2293 T2643 T2644 arg1Of film,(
R2294 T2646 T2644 arg2Of Hyperfilm,(
R2295 T2646 T2645 arg1Of Hyperfilm,Fuji
R2296 T2646 T2647 arg1Of Hyperfilm,","
R2297 T2648 T2647 arg2Of Tokyo,","
R2298 T2648 T2649 arg1Of Tokyo,","
R2299 T2650 T2649 arg2Of Japan,","
R2300 T2651 T2644 arg3Of ),(
R2301 T2652 T2653 arg1Of Levels,of
R2302 T2652 T2658 arg1Of Levels,were
R2303 T2652 T2659 arg2Of Levels,quantified
R2304 T2657 T2653 arg2Of activity,of
R2305 T2657 T2654 arg1Of activity,NF-κB
R2306 T2657 T2655 arg1Of activity,DNA
R2307 T2657 T2656 arg1Of activity,binding
R2308 T2659 T2658 arg2Of quantified,were
R2309 T2662 T2659 arg1Of ImageJ,quantified
R2310 T2662 T2660 arg2Of ImageJ,by
R2311 T2662 T2661 arg1Of ImageJ,software
R2677 T3118 T3117 arg1Of RNA,Total
R2678 T3118 T3119 arg1Of RNA,was
R2679 T3118 T3120 arg2Of RNA,isolated
R2680 T3120 T3119 arg2Of isolated,was
R2681 T3120 T3121 arg1Of isolated,with
R2682 T3120 T3131 arg1Of isolated,and
R2683 T3122 T3121 arg2Of Trizol,with
R2684 T3122 T3123 arg1Of Trizol,(
R2685 T3124 T3123 arg2Of Invitrogen,(
R2686 T3124 T3125 arg1Of Invitrogen,","
R2687 T3124 T3127 arg1Of Invitrogen,","
R2688 T3124 T3128 arg1Of Invitrogen,USA
R2689 T3126 T3125 arg2Of CA,","
R2690 T3129 T3123 arg3Of ),(
R2691 T3131 T3130 arg1Of and,","
R2692 T3131 T3145 arg1Of and,(
R2693 T3131 T3152 arg1Of and,according
R2694 T3133 T3132 arg1Of cDNA,single-stranded
R2695 T3133 T3134 arg1Of cDNA,was
R2696 T3133 T3135 arg2Of cDNA,synthesized
R2697 T3135 T3131 arg2Of synthesized,and
R2698 T3135 T3134 arg2Of synthesized,was
R2699 T3135 T3136 arg1Of synthesized,from
R2700 T3138 T3136 arg2Of μg,from
R2701 T3138 T3137 arg1Of μg,2
R2702 T3138 T3139 arg1Of μg,of
R2703 T3141 T3139 arg2Of RNA,of
R2704 T3141 T3140 arg1Of RNA,total
R2705 T3141 T3142 arg1Of RNA,with
R2706 T3144 T3142 arg2Of RT-Kit,with
R2707 T3144 T3143 arg1Of RT-Kit,BU-Script
R2708 T3146 T3147 arg1Of Biunique,","
R2709 T3147 T3145 arg2Of ",",(
R2710 T3147 T3149 arg1Of ",",","
R2711 T3148 T3147 arg2Of Jiangsu,","
R2712 T3150 T3149 arg2Of China,","
R2713 T3151 T3145 arg3Of ),(
R2714 T3153 T3152 arg2Of to,according
R2715 T3155 T3154 arg1Of manufacturer,the
R2716 T3155 T3156 arg2Of manufacturer,'s
R2717 T3157 T3153 arg2Of protocol,to
R2718 T3157 T3156 arg1Of protocol,'s
R2719 T3159 T3158 arg1Of cDNA,The
R2720 T3159 T3160 arg1Of cDNA,was
R2721 T3159 T3161 arg2Of cDNA,stored
R2722 T3161 T3160 arg2Of stored,was
R2723 T3161 T3162 arg1Of stored,in
R2724 T3163 T3162 arg2Of −20°C,in
R2725 T3165 T3164 arg1Of transcription,Reverse
R2726 T3165 T3166 arg1Of transcription,was
R2727 T3165 T3167 arg2Of transcription,conducted
R2728 T3167 T3166 arg2Of conducted,was
R2729 T3167 T3168 arg1Of conducted,with
R2730 T3167 T3180 arg1Of conducted,according
R2731 T3172 T3168 arg2Of Mix,with
R2732 T3172 T3169 arg1Of Mix,GoTaq
R2733 T3172 T3170 arg1Of Mix,Green
R2734 T3172 T3171 arg1Of Mix,Master
R2735 T3172 T3173 arg1Of Mix,(
R2736 T3174 T3175 arg1Of Promega,","
R2737 T3175 T3173 arg2Of ",",(
R2738 T3175 T3177 arg1Of ",",","
R2739 T3175 T3178 arg1Of ",",USA
R2740 T3176 T3175 arg2Of WI,","
R2741 T3179 T3173 arg3Of ),(
R2742 T3181 T3180 arg2Of to,according
R2743 T3183 T3182 arg1Of manufacturer,the
R2744 T3183 T3184 arg2Of manufacturer,'s
R2745 T3185 T3181 arg2Of protocol,to
R2746 T3185 T3184 arg1Of protocol,'s
R2747 T3187 T3186 arg1Of 1,Table
R2748 T3187 T3188 arg1Of 1,shows
R2749 T3190 T3191 arg1Of primers,and
R2750 T3191 T3188 arg2Of and,shows
R2751 T3191 T3189 arg1Of and,the
R2752 T3193 T3191 arg2Of parameters,and
R2753 T3193 T3192 arg1Of parameters,PCR
R2754 T3195 T3194 arg1Of products,PCR
R2755 T3195 T3196 arg1Of products,were
R2756 T3195 T3197 arg2Of products,detected
R2757 T3197 T3196 arg2Of detected,were
R2758 T3201 T3197 arg1Of electrophoresis,detected
R2759 T3201 T3198 arg2Of electrophoresis,by
R2760 T3201 T3199 arg1Of electrophoresis,agarose
R2761 T3201 T3200 arg1Of electrophoresis,gel
R2762 T3203 T3202 arg1Of intensity,The
R2763 T3203 T3204 arg1Of intensity,of
R2764 T3203 T3207 arg1Of intensity,was
R2765 T3203 T3208 arg2Of intensity,analyzed
R2766 T3206 T3204 arg2Of bands,of
R2767 T3206 T3205 arg1Of bands,the
R2768 T3208 T3207 arg2Of analyzed,was
R2769 T3211 T3208 arg1Of program,analyzed
R2770 T3211 T3209 arg2Of program,by
R2771 T3211 T3210 arg1Of program,ImageJ
R2772 T3213 T3212 arg1Of level,The
R2773 T3213 T3214 arg1Of level,of
R2774 T3213 T3216 arg1Of level,was
R2775 T3213 T3217 arg2Of level,used
R2776 T3215 T3214 arg2Of β-actin,of
R2777 T3217 T3216 arg2Of used,was
R2778 T3217 T3218 arg1Of used,as
R2779 T3221 T3218 arg2Of standard,as
R2780 T3221 T3219 arg1Of standard,an
R2781 T3221 T3220 arg1Of standard,internal
R2899 T3391 T3390 arg1Of Blot,Western
R2900 T3393 T3392 arg1Of obtain,To
R2901 T3396 T3393 arg2Of lysates,obtain
R2902 T3396 T3394 arg1Of lysates,total
R2903 T3396 T3395 arg1Of lysates,protein
R2904 T3398 T3393 arg1Of cells,obtain
R2905 T3398 T3399 arg1Of cells,were
R2906 T3398 T3400 arg2Of cells,homogenized
R2907 T3398 T3452 arg2Of cells,centrifuged
R2908 T3400 T3401 arg1Of homogenized,in
R2909 T3400 T3451 arg1Of homogenized,and
R2910 T3403 T3401 arg2Of buffer,in
R2911 T3403 T3402 arg1Of buffer,RIPA
R2912 T3403 T3404 arg1Of buffer,(
R2913 T3405 T3406 arg1Of 1,%
R2914 T3407 T3405 arg1Of NP40,1
R2915 T3407 T3408 arg1Of NP40,","
R2916 T3408 T3413 arg1Of ",",","
R2917 T3409 T3410 arg1Of 0.5,%
R2918 T3412 T3408 arg2Of deoxycholate,","
R2919 T3412 T3409 arg1Of deoxycholate,0.5
R2920 T3412 T3411 arg1Of deoxycholate,sodium
R2921 T3413 T3417 arg1Of ",",","
R2922 T3414 T3415 arg1Of 0.1,%
R2923 T3416 T3413 arg2Of SDS,","
R2924 T3416 T3414 arg1Of SDS,0.1
R2925 T3417 T3421 arg1Of ",",","
R2926 T3418 T3419 arg1Of 1,mM
R2927 T3420 T3417 arg2Of EDTA,","
R2928 T3420 T3418 arg1Of EDTA,1
R2929 T3421 T3404 arg2Of ",",(
R2930 T3421 T3425 arg1Of ",",","
R2931 T3422 T3423 arg1Of 1,mM
R2932 T3424 T3421 arg2Of EGTA,","
R2933 T3424 T3422 arg1Of EGTA,1
R2934 T3426 T3427 arg1Of 1,mM
R2935 T3428 T3426 arg1Of Na3VO4,1
R2936 T3428 T3429 arg1Of Na3VO4,","
R2937 T3429 T3433 arg1Of ",",","
R2938 T3430 T3431 arg1Of 20,mM
R2939 T3432 T3429 arg2Of NaF,","
R2940 T3432 T3430 arg1Of NaF,20
R2941 T3433 T3437 arg1Of ",",","
R2942 T3434 T3435 arg1Of 0.5,mM
R2943 T3436 T3433 arg2Of DTT,","
R2944 T3436 T3434 arg1Of DTT,0.5
R2945 T3437 T3442 arg1Of ",",and
R2946 T3438 T3439 arg1Of 1,mM
R2947 T3440 T3437 arg2Of PMSF,","
R2948 T3440 T3438 arg1Of PMSF,1
R2949 T3442 T3425 arg2Of and,","
R2950 T3442 T3441 arg1Of and,","
R2951 T3445 T3442 arg2Of cocktail,and
R2952 T3445 T3443 arg1Of cocktail,protease
R2953 T3445 T3444 arg1Of cocktail,inhibitor
R2954 T3445 T3446 arg1Of cocktail,in
R2955 T3448 T3446 arg2Of pH,in
R2956 T3448 T3447 arg1Of pH,PBS
R2957 T3448 T3449 arg1Of pH,7.4
R2958 T3450 T3404 arg3Of ),(
R2959 T3451 T3392 modOf and,To
R2960 T3451 T3397 arg1Of and,","
R2961 T3451 T3399 arg2Of and,were
R2962 T3452 T3451 arg2Of centrifuged,and
R2963 T3452 T3453 arg1Of centrifuged,at
R2964 T3452 T3456 arg1Of centrifuged,for
R2965 T3455 T3453 arg2Of g,at
R2966 T3455 T3454 arg1Of g,"12,000"
R2967 T3458 T3456 arg2Of min,for
R2968 T3458 T3457 arg1Of min,15
R2969 T3458 T3459 arg1Of min,at
R2970 T3460 T3459 arg2Of 4°C,at
R2971 T3462 T3461 arg1Of concentrations,Protein
R2972 T3462 T3463 arg1Of concentrations,were
R2973 T3462 T3464 arg2Of concentrations,estimated
R2974 T3464 T3463 arg2Of estimated,were
R2975 T3470 T3464 arg1Of Reagent,estimated
R2976 T3470 T3465 arg2Of Reagent,by
R2977 T3470 T3466 arg1Of Reagent,Coomassie
R2978 T3470 T3467 arg1Of Reagent,Plus
R2979 T3470 T3468 arg1Of Reagent,Protein
R2980 T3470 T3469 arg1Of Reagent,Assay
R2981 T3470 T3471 arg1Of Reagent,(
R2982 T3472 T3473 arg1Of Pierce,","
R2983 T3473 T3471 arg2Of ",",(
R2984 T3473 T3475 arg1Of ",",","
R2985 T3474 T3473 arg2Of IL,","
R2986 T3476 T3475 arg2Of USA,","
R2987 T3477 T3471 arg3Of ),(
R2988 T3479 T3478 arg1Of micrograms,Fifty
R2989 T3479 T3480 arg1Of micrograms,of
R2990 T3479 T3486 arg1Of micrograms,were
R2991 T3479 T3487 arg1Of micrograms,heat-denatured
R2992 T3479 T3506 arg1Of micrograms,electroblotted
R2993 T3485 T3480 arg2Of extracts,of
R2994 T3485 T3481 arg1Of extracts,the
R2995 T3485 T3482 arg1Of extracts,resulting
R2996 T3485 T3483 arg1Of extracts,cytosolic
R2997 T3485 T3484 arg1Of extracts,protein
R2998 T3486 T3488 arg1Of were,in
R2999 T3486 T3505 arg1Of were,and
R3000 T3487 T3486 arg2Of heat-denatured,were
R3001 T3492 T3488 arg2Of buffer,in
R3002 T3492 T3489 arg1Of buffer,Laemmli
R3003 T3492 T3490 arg1Of buffer,sample
R3004 T3492 T3491 arg1Of buffer,loading
R3005 T3492 T3493 arg1Of buffer,","
R3006 T3492 T3494 arg2Of buffer,separated
R3007 T3496 T3497 arg1Of 10,%
R3008 T3503 T3494 arg1Of electrophoresis,separated
R3009 T3503 T3495 arg2Of electrophoresis,by
R3010 T3503 T3496 arg1Of electrophoresis,10
R3011 T3503 T3498 arg1Of electrophoresis,sodium
R3012 T3503 T3499 arg1Of electrophoresis,dodecyl
R3013 T3503 T3500 arg1Of electrophoresis,sulfate
R3014 T3503 T3501 arg1Of electrophoresis,polyacrylamide
R3015 T3503 T3502 arg1Of electrophoresis,gel
R3016 T3505 T3504 arg1Of and,","
R3017 T3506 T3505 arg2Of electroblotted,and
R3018 T3506 T3507 arg1Of electroblotted,onto
R3019 T3510 T3507 arg2Of membrane,onto
R3020 T3510 T3508 arg1Of membrane,a
R3021 T3510 T3509 arg1Of membrane,nitrocellulose
R3022 T3512 T3511 arg2Of immunoblotting,For
R3023 T3514 T3515 arg1Of membranes,were
R3024 T3514 T3516 arg2Of membranes,blocked
R3025 T3516 T3511 arg1Of blocked,For
R3026 T3516 T3513 arg1Of blocked,","
R3027 T3516 T3515 arg2Of blocked,were
R3028 T3516 T3517 arg1Of blocked,with
R3029 T3516 T3526 arg1Of blocked,overnight
R3030 T3516 T3527 arg1Of blocked,at
R3031 T3516 T3530 arg1Of blocked,and
R3032 T3518 T3519 arg1Of 5,%
R3033 T3522 T3517 arg2Of milk,with
R3034 T3522 T3518 arg1Of milk,5
R3035 T3522 T3520 arg1Of milk,nonfat
R3036 T3522 T3521 arg1Of milk,dry
R3037 T3522 T3523 arg1Of milk,in
R3038 T3525 T3523 arg2Of buffer,in
R3039 T3525 T3524 arg1Of buffer,saline
R3040 T3528 T3527 arg2Of 4°C,at
R3041 T3530 T3529 arg1Of and,","
R3042 T3530 T3536 arg1Of and,:
R3043 T3530 T3537 arg1Of and,anti-β-actin
R3044 T3530 T3554 arg1Of and,metallopeptidase
R3045 T3533 T3531 arg1Of antibodies,the
R3046 T3533 T3532 arg1Of antibodies,following
R3047 T3533 T3534 arg1Of antibodies,were
R3048 T3533 T3535 arg2Of antibodies,used
R3049 T3535 T3530 arg2Of used,and
R3050 T3535 T3534 arg2Of used,were
R3051 T3537 T3538 arg1Of anti-β-actin,(
R3052 T3537 T3552 arg1Of anti-β-actin,and
R3053 T3539 T3540 arg1Of sc-130657,","
R3054 T3539 T3544 arg1Of sc-130657,","
R3055 T3543 T3540 arg2Of Biotechnology,","
R3056 T3543 T3541 arg1Of Biotechnology,Santa
R3057 T3543 T3542 arg1Of Biotechnology,Cruz
R3058 T3544 T3538 arg2Of ",",(
R3059 T3545 T3546 arg1Of CA,","
R3060 T3546 T3548 arg1Of ",",","
R3061 T3547 T3546 arg2Of USA,","
R3062 T3549 T3548 arg2Of 43,","
R3063 T3550 T3544 arg2Of kDa,","
R3064 T3550 T3545 arg1Of kDa,CA
R3065 T3550 T3547 arg1Of kDa,USA
R3066 T3550 T3549 arg1Of kDa,43
R3067 T3551 T3538 arg3Of ),(
R3068 T3552 T3559 arg1Of and,(
R3069 T3554 T3552 arg2Of metallopeptidase,and
R3070 T3554 T3553 arg1Of metallopeptidase,anti-matrix
R3071 T3554 T3555 arg1Of metallopeptidase,9
R3072 T3554 T3556 arg1Of metallopeptidase,(
R3073 T3557 T3556 arg2Of MMP9,(
R3074 T3558 T3556 arg3Of ),(
R3075 T3560 T3561 arg1Of sc-6841,","
R3076 T3560 T3565 arg1Of sc-6841,","
R3077 T3564 T3561 arg2Of Biotechnology,","
R3078 T3564 T3562 arg1Of Biotechnology,Santa
R3079 T3564 T3563 arg1Of Biotechnology,Cruz
R3080 T3565 T3559 arg2Of ",",(
R3081 T3566 T3567 arg1Of CA,","
R3082 T3567 T3569 arg1Of ",",","
R3083 T3568 T3567 arg2Of USA,","
R3084 T3570 T3569 arg2Of 92,","
R3085 T3571 T3565 arg2Of kDa,","
R3086 T3571 T3566 arg1Of kDa,CA
R3087 T3571 T3568 arg1Of kDa,USA
R3088 T3571 T3570 arg1Of kDa,92
R3089 T3572 T3559 arg3Of ),(
R3090 T3575 T3573 arg1Of antibody,Each
R3091 T3575 T3574 arg1Of antibody,primary
R3092 T3575 T3576 arg1Of antibody,was
R3093 T3575 T3577 arg2Of antibody,diluted
R3094 T3575 T3584 arg1Of antibody,added
R3095 T3577 T3576 arg2Of diluted,was
R3096 T3577 T3578 arg1Of diluted,appropriately
R3097 T3577 T3579 arg1Of diluted,in
R3098 T3577 T3582 arg1Of diluted,and
R3099 T3580 T3579 arg2Of blocking,in
R3100 T3581 T3580 arg2Of buffer,blocking
R3101 T3584 T3582 arg2Of added,and
R3102 T3584 T3583 arg1Of added,then
R3103 T3584 T3585 arg1Of added,to
R3104 T3584 T3588 arg1Of added,for
R3105 T3587 T3585 arg2Of blots,to
R3106 T3587 T3586 arg1Of blots,the
R3107 T3590 T3588 arg2Of h,for
R3108 T3590 T3589 arg1Of h,1
R3109 T3590 T3591 arg1Of h,at
R3110 T3593 T3591 arg2Of temperature,at
R3111 T3593 T3592 arg1Of temperature,room
R3112 T3595 T3594 arg1Of blots,The
R3113 T3595 T3596 arg1Of blots,were
R3114 T3595 T3597 arg2Of blots,washed
R3115 T3595 T3605 arg2Of blots,covered
R3116 T3597 T3599 arg1Of washed,times
R3117 T3597 T3600 arg1Of washed,in
R3118 T3597 T3604 arg1Of washed,and
R3119 T3599 T3598 arg1Of times,three
R3120 T3603 T3600 arg2Of buffer,in
R3121 T3603 T3601 arg1Of buffer,the
R3122 T3603 T3602 arg1Of buffer,washing
R3123 T3604 T3596 arg2Of and,were
R3124 T3605 T3604 arg2Of covered,and
R3125 T3605 T3606 arg1Of covered,with
R3126 T3605 T3612 arg1Of covered,at
R3127 T3611 T3606 arg2Of antibody,with
R3128 T3611 T3607 arg1Of antibody,the
R3129 T3611 T3608 arg1Of antibody,horseradish
R3130 T3611 T3609 arg1Of antibody,peroxidase-linked
R3131 T3611 T3610 arg1Of antibody,secondary
R3132 T3614 T3612 arg2Of 1,at
R3133 T3614 T3613 arg1Of 1,a
R3134 T3614 T3615 arg1Of 1,:
R3135 T3617 T3616 arg1Of dilution,2000
R3136 T3617 T3618 arg1Of dilution,for
R3137 T3620 T3618 arg2Of h,for
R3138 T3620 T3619 arg1Of h,1
R3139 T3621 T3622 arg1Of Blots,were
R3140 T3621 T3623 arg2Of Blots,incubated
R3141 T3621 T3641 arg2Of Blots,exposed
R3142 T3623 T3624 arg1Of incubated,with
R3143 T3623 T3640 arg1Of incubated,and
R3144 T3628 T3627 arg2Of ECL,(
R3145 T3629 T3627 arg3Of ),(
R3146 T3631 T3624 arg2Of system,with
R3147 T3631 T3625 arg2Of system,enhanced
R3148 T3631 T3626 arg1Of system,chemiluminescence
R3149 T3631 T3627 arg1Of system,(
R3150 T3631 T3630 arg1Of system,detection
R3151 T3631 T3632 arg1Of system,(
R3152 T3634 T3632 arg2Of Biosciences,(
R3153 T3634 T3633 arg1Of Biosciences,Amersham
R3154 T3634 T3635 arg1Of Biosciences,","
R3155 T3636 T3635 arg2Of Bucks,","
R3156 T3636 T3637 arg1Of Bucks,","
R3157 T3638 T3637 arg2Of UK,","
R3158 T3639 T3632 arg3Of ),(
R3159 T3640 T3622 arg2Of and,were
R3160 T3641 T3640 arg2Of exposed,and
R3161 T3641 T3642 arg1Of exposed,to
R3162 T3644 T3642 arg2Of film,to
R3163 T3644 T3643 arg1Of film,radiographic
R3164 T3644 T3645 arg1Of film,(
R3165 T3647 T3645 arg2Of Hyperfilm,(
R3166 T3647 T3646 arg1Of Hyperfilm,Fuji
R3167 T3647 T3648 arg1Of Hyperfilm,","
R3168 T3649 T3648 arg2Of Tokyo,","
R3169 T3649 T3650 arg1Of Tokyo,","
R3170 T3651 T3650 arg2Of Japan,","
R3171 T3652 T3645 arg3Of ),(
R3172 T3653 T3654 arg1Of ImageJ,was
R3173 T3653 T3655 arg2Of ImageJ,used
R3174 T3655 T3654 arg2Of used,was
R3175 T3657 T3655 arg3Of analyze,used
R3176 T3657 T3656 arg1Of analyze,to
R3177 T3659 T3657 arg2Of intensity,analyze
R3178 T3659 T3658 arg1Of intensity,the
R3179 T3659 T3660 arg1Of intensity,of
R3180 T3662 T3660 arg2Of blots,of
R3181 T3662 T3661 arg1Of blots,the
R3182 T3664 T3663 arg1Of level,The
R3183 T3664 T3665 arg1Of level,of
R3184 T3664 T3667 arg1Of level,was
R3185 T3664 T3668 arg2Of level,used
R3186 T3666 T3665 arg2Of β-actin,of
R3187 T3668 T3667 arg2Of used,was
R3188 T3668 T3669 arg1Of used,as
R3189 T3671 T3669 arg2Of standard,as
R3190 T3671 T3670 arg1Of standard,internal
R3492 T4084 T4082 arg1Of Assay,Enzyme-Linked
R3493 T4084 T4083 arg1Of Assay,Immunosorbent
R3494 T4084 T4085 arg1Of Assay,(
R3495 T4086 T4085 arg2Of ELISA,(
R3496 T4087 T4085 arg3Of ),(
R3497 T4088 T4089 arg1Of Cells,of
R3498 T4088 T4092 arg1Of Cells,were
R3499 T4088 T4093 arg2Of Cells,homogenized
R3500 T4091 T4089 arg2Of groups,of
R3501 T4091 T4090 arg1Of groups,four
R3502 T4093 T4092 arg2Of homogenized,were
R3503 T4093 T4094 arg1Of homogenized,as
R3504 T4095 T4094 arg2Of mentioned,as
R3505 T4095 T4096 arg1Of mentioned,above
R3506 T4098 T4097 arg1Of supernatant,The
R3507 T4098 T4099 arg1Of supernatant,was
R3508 T4098 T4100 arg2Of supernatant,collected
R3509 T4100 T4099 arg2Of collected,was
R3510 T4100 T4102 arg1Of collected,and
R3511 T4102 T4101 arg1Of and,","
R3512 T4104 T4103 arg1Of protein,total
R3513 T4104 T4105 arg1Of protein,was
R3514 T4104 T4106 arg2Of protein,determined
R3515 T4106 T4102 arg2Of determined,and
R3516 T4106 T4105 arg2Of determined,was
R3517 T4112 T4106 arg1Of Reagent,determined
R3518 T4112 T4107 arg2Of Reagent,by
R3519 T4112 T4108 arg1Of Reagent,Coomassie
R3520 T4112 T4109 arg1Of Reagent,Plus
R3521 T4112 T4110 arg1Of Reagent,Protein
R3522 T4112 T4111 arg1Of Reagent,Assay
R3523 T4112 T4113 arg1Of Reagent,(
R3524 T4114 T4115 arg1Of Pierce,","
R3525 T4115 T4113 arg2Of ",",(
R3526 T4115 T4117 arg1Of ",",","
R3527 T4116 T4115 arg2Of IL,","
R3528 T4118 T4117 arg2Of USA,","
R3529 T4119 T4113 arg3Of ),(
R3530 T4120 T4121 arg1Of Levels,of
R3531 T4120 T4135 arg1Of Levels,and
R3532 T4124 T4122 arg1Of factor-alpha,tumor
R3533 T4124 T4123 arg1Of factor-alpha,necrosis
R3534 T4124 T4125 arg1Of factor-alpha,(
R3535 T4124 T4128 arg1Of factor-alpha,","
R3536 T4126 T4125 arg2Of TNF-α,(
R3537 T4127 T4125 arg3Of ),(
R3538 T4128 T4121 arg2Of ",",of
R3539 T4130 T4128 arg2Of beta,","
R3540 T4130 T4129 arg1Of beta,interleukin-1
R3541 T4130 T4131 arg1Of beta,(
R3542 T4132 T4131 arg2Of IL-1β,(
R3543 T4133 T4131 arg3Of ),(
R3544 T4135 T4134 arg1Of and,","
R3545 T4136 T4135 arg2Of interleukin-6,and
R3546 T4136 T4137 arg1Of interleukin-6,(
R3547 T4136 T4141 modOf interleukin-6,were
R3548 T4138 T4137 arg2Of IL-6,(
R3549 T4139 T4137 arg3Of ),(
R3550 T4140 T4141 arg1Of protein,were
R3551 T4140 T4142 arg2Of protein,quantified
R3552 T4142 T4141 arg2Of quantified,were
R3553 T4143 T4142 arg3Of using,quantified
R3554 T4143 T4149 arg1Of using,according
R3555 T4145 T4143 arg2Of kits,using
R3556 T4145 T4144 arg1Of kits,ELISA
R3557 T4145 T4146 arg1Of kits,specific
R3558 T4146 T4147 arg1Of specific,for
R3559 T4148 T4147 arg2Of mouse,for
R3560 T4150 T4149 arg2Of to,according
R3561 T4152 T4151 arg1Of manufacturer,the
R3562 T4152 T4153 arg2Of manufacturer,'s
R3563 T4154 T4150 arg2Of instructions,to
R3564 T4154 T4153 arg1Of instructions,'s
R3565 T4154 T4155 arg1Of instructions,(
R3566 T4159 T4155 arg2Of CA,(
R3567 T4159 T4156 arg1Of CA,Bender
R3568 T4159 T4157 arg1Of CA,MedSystems
R3569 T4159 T4158 arg1Of CA,Inc.
R3570 T4159 T4160 arg1Of CA,","
R3571 T4159 T4161 arg1Of CA,USA
R3572 T4162 T4155 arg3Of ),(
R3573 T4163 T4165 arg1Of Briefly,prepared
R3574 T4163 T4169 arg1Of Briefly,created
R3575 T4165 T4168 arg1Of prepared,and
R3576 T4167 T4165 arg2Of standard,prepared
R3577 T4167 T4166 arg1Of standard,the
R3578 T4168 T4164 arg1Of and,","
R3579 T4169 T4168 arg2Of created,and
R3580 T4172 T4169 arg2Of dilution,created
R3581 T4172 T4170 arg1Of dilution,the
R3582 T4172 T4171 arg1Of dilution,standard
R3583 T4172 T4173 arg1Of dilution,for
R3584 T4174 T4173 arg2Of building,for
R3585 T4176 T4174 arg2Of curve,building
R3586 T4176 T4175 arg1Of curve,standard
R3587 T4178 T4179 arg1Of samples,and
R3588 T4179 T4177 arg1Of and,Then
R3589 T4179 T4181 arg1Of and,were
R3590 T4179 T4182 arg2Of and,added
R3591 T4180 T4179 arg2Of biotinconjugate,and
R3592 T4182 T4181 arg2Of added,were
R3593 T4182 T4183 modOf added,to
R3594 T4184 T4183 arg1Of microwell,to
R3595 T4185 T4184 arg2Of strips,microwell
R3596 T4187 T4188 arg1Of incubated,for
R3597 T4190 T4188 arg2Of h,for
R3598 T4190 T4189 arg1Of h,2
R3599 T4190 T4191 arg1Of h,at
R3600 T4192 T4186 arg1Of room,After
R3601 T4192 T4187 arg2Of room,incubated
R3602 T4193 T4192 arg1Of temperature,room
R3603 T4193 T4194 arg1Of temperature,","
R3604 T4193 T4198 arg1Of temperature,were
R3605 T4193 T4199 arg2Of temperature,washed
R3606 T4197 T4194 arg2Of strips,","
R3607 T4197 T4195 arg1Of strips,the
R3608 T4197 T4196 arg1Of strips,microwell
R3609 T4199 T4198 arg2Of washed,were
R3610 T4199 T4202 arg1Of washed,with
R3611 T4199 T4206 arg1Of washed,and
R3612 T4201 T4199 arg3Of times,washed
R3613 T4201 T4200 arg1Of times,3
R3614 T4204 T4202 arg2Of buffer,with
R3615 T4204 T4203 arg1Of buffer,wash
R3616 T4206 T4205 arg1Of and,","
R3617 T4207 T4208 arg1Of streptavidin-HRP,were
R3618 T4207 T4209 arg2Of streptavidin-HRP,added
R3619 T4209 T4206 arg2Of added,and
R3620 T4209 T4208 arg2Of added,were
R3621 T4209 T4210 arg1Of added,to
R3622 T4212 T4210 arg2Of wells,to
R3623 T4212 T4211 arg1Of wells,all
R3624 T4214 T4215 arg1Of incubated,for
R3625 T4217 T4215 arg2Of h,for
R3626 T4217 T4216 arg1Of h,1
R3627 T4220 T4213 arg1Of strips,After
R3628 T4220 T4214 arg2Of strips,incubated
R3629 T4220 T4218 arg1Of strips,","
R3630 T4220 T4219 arg1Of strips,microwell
R3631 T4220 T4221 arg1Of strips,were
R3632 T4220 T4222 arg2Of strips,washed
R3633 T4222 T4221 arg2Of washed,were
R3634 T4224 T4222 arg3Of times,washed
R3635 T4224 T4223 arg1Of times,3
R3636 T4224 T4225 arg2Of times,followed
R3637 T4225 T4226 arg1Of followed,by
R3638 T4227 T4226 arg2Of adding,by
R3639 T4229 T4227 arg2Of substrate,adding
R3640 T4229 T4228 arg1Of substrate,TMB
R3641 T4231 T4232 arg1Of incubated,for
R3642 T4234 T4230 arg1Of 10–30,After
R3643 T4234 T4231 arg2Of 10–30,incubated
R3644 T4234 T4233 arg1Of 10–30,about
R3645 T4235 T4234 arg1Of min,10–30
R3646 T4235 T4236 arg1Of min,","
R3647 T4235 T4240 arg1Of min,was
R3648 T4235 T4241 arg2Of min,added
R3649 T4239 T4236 arg2Of solution,","
R3650 T4239 T4237 arg1Of solution,the
R3651 T4239 T4238 arg1Of solution,stop
R3652 T4241 T4240 arg2Of added,was
R3653 T4244 T4242 arg1Of intensity,The
R3654 T4244 T4243 arg1Of intensity,colour
R3655 T4244 T4245 arg1Of intensity,was
R3656 T4244 T4246 arg2Of intensity,measured
R3657 T4244 T4250 arg1Of intensity,using
R3658 T4246 T4245 arg2Of measured,was
R3659 T4246 T4247 arg1Of measured,at
R3660 T4246 T4250 modOf measured,using
R3661 T4249 T4247 arg2Of nm,at
R3662 T4249 T4248 arg1Of nm,450
R3663 T4250 T4256 arg1Of using,(
R3664 T4255 T4250 arg2Of reader,using
R3665 T4255 T4251 arg1Of reader,a
R3666 T4255 T4252 arg1Of reader,Bio-Rad
R3667 T4255 T4253 arg1Of reader,ELISA
R3668 T4255 T4254 arg1Of reader,microplate
R3669 T4258 T4256 arg2Of Laboratories,(
R3670 T4258 T4257 arg1Of Laboratories,Bio-Rad
R3671 T4258 T4259 arg1Of Laboratories,","
R3672 T4260 T4259 arg2Of CA,","
R3673 T4260 T4261 arg1Of CA,","
R3674 T4262 T4261 arg2Of USA,","
R3675 T4263 T4256 arg3Of ),(
R3676 T4265 T4264 arg1Of concentration,The
R3677 T4265 T4266 arg1Of concentration,of
R3678 T4265 T4268 arg1Of concentration,was
R3679 T4265 T4269 arg2Of concentration,determined
R3680 T4265 T4276 arg2Of concentration,expressed
R3681 T4267 T4266 arg2Of protein,of
R3682 T4269 T4270 arg1Of determined,according
R3683 T4269 T4275 arg1Of determined,and
R3684 T4271 T4270 arg2Of to,according
R3685 T4274 T4271 arg2Of curve,to
R3686 T4274 T4272 arg1Of curve,the
R3687 T4274 T4273 arg1Of curve,standard
R3688 T4275 T4268 arg2Of and,was
R3689 T4276 T4275 arg2Of expressed,and
R3690 T4276 T4277 arg1Of expressed,as
R3691 T4278 T4277 arg2Of pg/mg,as
R3692 T4278 T4279 arg1Of pg/mg,of
R3693 T4281 T4279 arg2Of protein,of
R3694 T4281 T4280 arg1Of protein,total
R3709 T4394 T4393 arg1Of Zymography,Gelatine
R3710 T4395 T4396 arg1Of Cells,of
R3711 T4395 T4399 arg1Of Cells,were
R3712 T4395 T4400 arg2Of Cells,homogenized
R3713 T4398 T4396 arg2Of groups,of
R3714 T4398 T4397 arg1Of groups,four
R3715 T4400 T4399 arg2Of homogenized,were
R3716 T4400 T4401 arg1Of homogenized,in
R3717 T4400 T4425 arg1Of homogenized,and
R3718 T4403 T4401 arg2Of buffer,in
R3719 T4403 T4402 arg1Of buffer,lysis
R3720 T4403 T4404 arg1Of buffer,containing
R3721 T4405 T4406 arg1Of 50,mM
R3722 T4407 T4405 arg1Of Tris-HCl,50
R3723 T4407 T4408 arg1Of Tris-HCl,(
R3724 T4407 T4412 arg1Of Tris-HCl,","
R3725 T4409 T4408 arg2Of pH,(
R3726 T4409 T4410 arg1Of pH,7.4
R3727 T4411 T4408 arg3Of ),(
R3728 T4412 T4416 arg1Of ",",","
R3729 T4413 T4414 arg1Of 150,mM
R3730 T4415 T4412 arg2Of NaCl,","
R3731 T4415 T4413 arg1Of NaCl,150
R3732 T4416 T4420 arg1Of ",",","
R3733 T4417 T4418 arg1Of 5,mM
R3734 T4419 T4416 arg2Of CaCl2,","
R3735 T4419 T4417 arg1Of CaCl2,5
R3736 T4420 T4404 arg2Of ",",containing
R3737 T4421 T4422 arg1Of 0.2,mM
R3738 T4423 T4420 arg2Of NaN3,","
R3739 T4423 T4421 arg1Of NaN3,0.2
R3740 T4425 T4424 arg1Of and,","
R3741 T4427 T4426 arg1Of %,0.01
R3742 T4429 T4428 arg1Of Soluble,Triton.
R3743 T4430 T4429 arg1Of extracts,Soluble
R3744 T4430 T4431 arg1Of extracts,were
R3745 T4430 T4432 arg2Of extracts,separated
R3746 T4430 T4436 arg2Of extracts,stored
R3747 T4432 T4435 arg1Of separated,and
R3748 T4434 T4432 arg1Of centrifugation,separated
R3749 T4434 T4433 arg2Of centrifugation,by
R3750 T4435 T4425 arg2Of and,and
R3751 T4435 T4427 arg1Of and,%
R3752 T4435 T4431 arg2Of and,were
R3753 T4436 T4435 arg2Of stored,and
R3754 T4436 T4437 arg1Of stored,at
R3755 T4438 T4437 arg2Of –20°C,at
R3756 T4440 T4439 arg1Of zymography,Gelatin
R3757 T4440 T4441 arg1Of zymography,was
R3758 T4440 T4442 arg2Of zymography,performed
R3759 T4442 T4441 arg2Of performed,was
R3760 T4442 T4443 arg1Of performed,according
R3761 T4444 T4443 arg2Of to,according
R3762 T4446 T4445 arg1Of manufacturer,the
R3763 T4446 T4447 arg2Of manufacturer,'s
R3764 T4448 T4444 arg2Of instructions,to
R3765 T4448 T4447 arg1Of instructions,'s
R3766 T4448 T4449 arg1Of instructions,(
R3767 T4452 T4449 arg2Of Inc,(
R3768 T4452 T4450 arg1Of Inc,Genmed
R3769 T4452 T4451 arg1Of Inc,Scientifics
R3770 T4452 T4453 arg1Of Inc,","
R3771 T4454 T4453 arg2Of MA,","
R3772 T4454 T4455 arg1Of MA,","
R3773 T4456 T4455 arg2Of USA,","
R3774 T4457 T4449 arg3Of ),(
R3775 T4464 T4460 arg1Of extracts,40
R3776 T4464 T4461 arg1Of extracts,μg
R3777 T4464 T4462 arg1Of extracts,cytosolic
R3778 T4464 T4463 arg1Of extracts,protein
R3779 T4464 T4465 arg1Of extracts,were
R3780 T4464 T4466 arg2Of extracts,separated
R3781 T4466 T4458 arg1Of separated,Briefly
R3782 T4466 T4459 arg1Of separated,","
R3783 T4466 T4465 arg2Of separated,were
R3784 T4468 T4466 arg1Of electrophoresis,separated
R3785 T4468 T4467 arg2Of electrophoresis,by
R3786 T4471 T4470 arg1Of proteins,the
R3787 T4471 T4472 arg1Of proteins,were
R3788 T4471 T4473 arg2Of proteins,renatured
R3789 T4471 T4483 arg2Of proteins,incubated
R3790 T4473 T4474 arg1Of renatured,by
R3791 T4473 T4481 arg1Of renatured,and
R3792 T4475 T4474 arg2Of incubation,by
R3793 T4475 T4476 arg1Of incubation,in
R3794 T4477 T4478 arg1Of 2.5,%
R3795 T4480 T4476 arg2Of X-100,in
R3796 T4480 T4477 arg1Of X-100,2.5
R3797 T4480 T4479 arg1Of X-100,Triton
R3798 T4481 T4469 arg1Of and,Then
R3799 T4481 T4472 arg2Of and,were
R3800 T4483 T4481 arg2Of incubated,and
R3801 T4483 T4482 arg1Of incubated,then
R3802 T4483 T4484 arg1Of incubated,in
R3803 T4483 T4487 arg1Of incubated,for
R3804 T4483 T4490 arg1Of incubated,at
R3805 T4483 T4492 modOf incubated,to
R3806 T4486 T4484 arg2Of buffer,in
R3807 T4486 T4485 arg1Of buffer,substrate
R3808 T4489 T4487 arg2Of h,for
R3809 T4489 T4488 arg1Of h,40
R3810 T4491 T4490 arg2Of 37°C,at
R3811 T4493 T4492 arg1Of enable,to
R3812 T4495 T4493 arg2Of MMP9,enable
R3813 T4495 T4494 arg1Of MMP9,the
R3814 T4495 T4497 arg1Of MMP9,cleave
R3815 T4497 T4493 arg3Of cleave,enable
R3816 T4497 T4496 arg1Of cleave,to
R3817 T4499 T4497 arg2Of gelatin,cleave
R3818 T4499 T4498 arg1Of gelatin,the
R3819 T4501 T4500 arg2Of rinsing,After
R3820 T4501 T4502 arg1Of rinsing,in
R3821 T4503 T4502 arg2Of water,in
R3822 T4506 T4501 arg1Of gel,rinsing
R3823 T4506 T4505 arg1Of gel,each
R3824 T4506 T4507 arg1Of gel,was
R3825 T4506 T4508 arg2Of gel,stained
R3826 T4506 T4511 arg1Of gel,blue
R3827 T4506 T4516 arg2Of gel,destained
R3828 T4508 T4509 arg1Of stained,with
R3829 T4508 T4515 arg1Of stained,and
R3830 T4510 T4509 arg2Of Coomassie,with
R3831 T4511 T4508 arg3Of blue,stained
R3832 T4511 T4512 arg1Of blue,for
R3833 T4514 T4512 arg2Of h,for
R3834 T4514 T4513 arg1Of h,1
R3835 T4515 T4500 arg1Of and,After
R3836 T4515 T4504 arg1Of and,","
R3837 T4515 T4507 arg2Of and,was
R3838 T4516 T4515 arg2Of destained,and
R3839 T4516 T4517 arg1Of destained,in
R3840 T4518 T4519 arg1Of 50,%
R3841 T4520 T4517 arg2Of methanol,in
R3842 T4520 T4518 arg1Of methanol,50
R3843 T4522 T4521 arg1Of activities,Proteolytic
R3844 T4522 T4523 arg1Of activities,were
R3845 T4522 T4524 arg2Of activities,showed
R3846 T4524 T4523 arg2Of showed,were
R3847 T4527 T4524 arg1Of bands,showed
R3848 T4527 T4525 arg2Of bands,by
R3849 T4527 T4526 arg1Of bands,clear
R3850 T4527 T4528 arg1Of bands,in
R3851 T4530 T4528 arg2Of gel,in
R3852 T4530 T4529 arg1Of gel,blue
R3853 T4530 T4531 arg1Of gel,which
R3854 T4530 T4532 arg1Of gel,indicates
R3855 T4534 T4532 arg2Of lysis,indicates
R3856 T4534 T4533 arg1Of lysis,the
R3857 T4534 T4535 arg1Of lysis,of
R3858 T4537 T4535 arg2Of substrate,of
R3859 T4537 T4536 arg1Of substrate,the
R3860 T4538 T4539 arg1Of Quantification,of
R3861 T4538 T4543 arg1Of Quantification,was
R3862 T4538 T4544 arg2Of Quantification,performed
R3863 T4542 T4539 arg2Of density,of
R3864 T4542 T4540 arg1Of density,MMP9
R3865 T4542 T4541 arg1Of density,band
R3866 T4544 T4543 arg2Of performed,was
R3867 T4544 T4545 arg1Of performed,with
R3868 T4549 T4545 arg2Of ImageJ,with
R3869 T4549 T4546 arg1Of ImageJ,image
R3870 T4549 T4547 arg1Of ImageJ,analysis
R3871 T4549 T4548 arg1Of ImageJ,program
R4043 T4764 T4763 arg1Of Analysis,Statistical
R4044 T4765 T4766 arg1Of Data,were
R4045 T4765 T4767 arg2Of Data,expressed
R4046 T4765 T4773 arg2Of Data,evaluated
R4047 T4767 T4768 arg1Of expressed,as
R4048 T4767 T4772 arg1Of expressed,and
R4049 T4771 T4768 arg2Of SD,as
R4050 T4771 T4769 arg1Of SD,mean
R4051 T4771 T4770 arg1Of SD,±
R4052 T4772 T4766 arg2Of and,were
R4053 T4773 T4772 arg2Of evaluated,and
R4054 T4775 T4776 arg1Of ANOVA,and
R4055 T4777 T4776 arg2Of LSD,and
R4056 T4780 T4773 arg1Of test,evaluated
R4057 T4780 T4774 arg2Of test,by
R4058 T4780 T4775 arg1Of test,ANOVA
R4059 T4780 T4777 arg1Of test,LSD
R4060 T4780 T4778 arg1Of test,multiple
R4061 T4780 T4779 arg1Of test,comparison
R4062 T4782 T4781 arg1Of values,P
R4063 T4782 T4783 arg1Of values,<
R4064 T4782 T4784 arg1Of values,0.05
R4065 T4782 T4785 arg1Of values,were
R4066 T4782 T4786 arg2Of values,considered
R4067 T4782 T4788 arg1Of values,be
R4068 T4782 T4789 arg1Of values,significant
R4069 T4786 T4785 arg2Of considered,were
R4070 T4788 T4786 arg3Of be,considered
R4071 T4788 T4787 arg1Of be,to
R4072 T4789 T4788 arg2Of significant,be
R4073 T4791 T4790 arg1Of analyses,All
R4074 T4791 T4792 arg1Of analyses,were
R4075 T4791 T4793 arg2Of analyses,performed
R4076 T4793 T4792 arg2Of performed,were
R4077 T4793 T4794 arg1Of performed,by
R4078 T4795 T4794 arg2Of using,by
R4079 T4798 T4795 arg2Of software,using
R4080 T4798 T4796 arg1Of software,SPSS
R4081 T4798 T4797 arg1Of software,18.0
R4123 T4857 T4858 arg1Of Depletion,of
R4124 T4857 T4860 arg1Of Depletion,Aggravated
R4125 T4859 T4858 arg2Of Nrf2,of
R4126 T4860 T4866 arg1Of Aggravated,after
R4127 T4863 T4860 arg2Of Death,Aggravated
R4128 T4863 T4861 arg1Of Death,the
R4129 T4863 T4862 arg1Of Death,Cell
R4130 T4863 T4864 arg1Of Death,in
R4131 T4865 T4864 arg2Of Astrocytes,in
R4132 T4868 T4866 arg2Of Injury,after
R4133 T4868 T4867 arg1Of Injury,Scratch
R4134 T4870 T4869 arg1Of death,Cell
R4135 T4870 T4871 arg1Of death,was
R4136 T4870 T4872 arg2Of death,detected
R4137 T4872 T4871 arg2Of detected,was
R4138 T4874 T4875 arg1Of microscope,and
R4139 T4876 T4875 arg2Of CCK-8,and
R4140 T4877 T4872 arg1Of analysis,detected
R4141 T4877 T4873 arg2Of analysis,by
R4142 T4877 T4874 arg1Of analysis,microscope
R4143 T4877 T4876 arg1Of analysis,CCK-8
R4144 T4877 T4878 arg1Of analysis,at
R4145 T4880 T4878 arg2Of h,at
R4146 T4880 T4879 arg1Of h,24
R4147 T4880 T4881 arg1Of h,after
R4148 T4882 T4881 arg2Of scratch,after
R4149 T4884 T4883 arg1Of detachment,The
R4150 T4884 T4885 arg1Of detachment,from
R4151 T4884 T4896 arg1Of detachment,were
R4152 T4884 T4898 arg2Of detachment,observed
R4153 T4887 T4886 arg1Of plate,culture
R4154 T4887 T4888 arg1Of plate,","
R4155 T4888 T4892 arg1Of ",",and
R4156 T4890 T4888 arg2Of lost,","
R4157 T4890 T4889 arg1Of lost,cell
R4158 T4892 T4885 arg2Of and,from
R4159 T4892 T4891 arg1Of and,","
R4160 T4895 T4892 arg2Of distortion,and
R4161 T4895 T4893 arg1Of distortion,cytoplasmic
R4162 T4895 T4894 arg1Of distortion,process
R4163 T4898 T4896 arg2Of observed,were
R4164 T4898 T4897 arg1Of observed,mostly
R4165 T4898 T4899 arg1Of observed,in
R4166 T4901 T4899 arg2Of sides,in
R4167 T4901 T4900 arg1Of sides,both
R4168 T4901 T4902 arg1Of sides,of
R4169 T4901 T4905 arg1Of sides,in
R4170 T4904 T4902 arg2Of line,of
R4171 T4904 T4903 arg1Of line,scratch
R4172 T4908 T4905 arg2Of TBI,in
R4173 T4908 T4906 arg1Of TBI,group
R4174 T4908 T4907 arg1Of TBI,KO
R4175 T4910 T4909 arg1Of assay,CCK-8
R4176 T4910 T4912 arg1Of assay,showed
R4177 T4912 T4911 arg1Of showed,also
R4178 T4915 T4912 arg2Of value,showed
R4179 T4915 T4913 arg1Of value,lower
R4180 T4915 T4914 arg1Of value,OD
R4181 T4915 T4916 arg1Of value,of
R4182 T4919 T4916 arg2Of TBI,of
R4183 T4919 T4917 arg1Of TBI,group
R4184 T4919 T4918 arg1Of TBI,KO
R4185 T4919 T4920 arg1Of TBI,(
R4186 T4919 T4925 arg1Of TBI,than
R4187 T4921 T4922 arg1Of 0.38,±
R4188 T4922 T4920 arg2Of ±,(
R4189 T4923 T4922 arg2Of 0.064,±
R4190 T4924 T4920 arg3Of ),(
R4191 T4926 T4925 arg2Of that,than
R4192 T4926 T4927 arg1Of that,of
R4193 T4930 T4927 arg2Of TBI,of
R4194 T4930 T4928 arg1Of TBI,group
R4195 T4930 T4929 arg1Of TBI,WT
R4196 T4930 T4931 arg1Of TBI,(
R4197 T4930 T4936 arg1Of TBI,(
R4198 T4930 T4941 arg1Of TBI,","
R4199 T4930 T4942 arg1Of TBI,which
R4200 T4930 T4944 arg1Of TBI,suggested
R4201 T4932 T4933 arg1Of 0.98,±
R4202 T4933 T4931 arg2Of ±,(
R4203 T4934 T4933 arg2Of 0.098,±
R4204 T4935 T4931 arg3Of ),(
R4205 T4937 T4936 arg2Of P,(
R4206 T4937 T4938 arg1Of P,<
R4207 T4937 T4939 arg1Of P,0.01
R4208 T4940 T4936 arg3Of ),(
R4209 T4944 T4943 arg1Of suggested,also
R4210 T4947 T4944 arg2Of death,suggested
R4211 T4947 T4945 arg1Of death,more
R4212 T4947 T4946 arg1Of death,cell
R4213 T4947 T4948 arg1Of death,in
R4214 T4951 T4948 arg2Of TBI,in
R4215 T4951 T4949 arg1Of TBI,group
R4216 T4951 T4950 arg1Of TBI,KO
R4217 T4951 T4952 arg1Of TBI,(
R4218 T4953 T4952 arg2Of Figure,(
R4219 T4953 T4954 arg1Of Figure,1
R4220 T4955 T4952 arg3Of ),(
R4221 T4956 T4957 arg1Of There,was
R4222 T4959 T4957 arg2Of difference,was
R4223 T4959 T4958 arg1Of difference,no
R4224 T4959 T4960 arg1Of difference,between
R4225 T4963 T4960 arg2Of groups,between
R4226 T4963 T4961 arg1Of groups,two
R4227 T4963 T4962 arg1Of groups,sham-operated
R4344 T5114 T5115 arg1Of Disruption,of
R4345 T5114 T5117 arg1Of Disruption,Enhanced
R4346 T5116 T5115 arg2Of Nrf2,of
R4347 T5117 T5123 arg1Of Enhanced,after
R4348 T5118 T5117 arg2Of Upregulation,Enhanced
R4349 T5118 T5119 arg1Of Upregulation,of
R4350 T5122 T5119 arg2Of Activity,of
R4351 T5122 T5120 arg1Of Activity,NF-κB
R4352 T5122 T5121 arg1Of Activity,DNA-Binding
R4353 T5125 T5123 arg2Of Injury,after
R4354 T5125 T5124 arg1Of Injury,Scratch
R4355 T5126 T5127 arg1Of It,has
R4356 T5126 T5128 arg1Of It,been
R4357 T5126 T5129 arg2Of It,reported
R4358 T5129 T5127 arg2Of reported,has
R4359 T5129 T5128 arg2Of reported,been
R4360 T5131 T5132 arg1Of NF-κB,is
R4361 T5131 T5133 arg2Of NF-κB,activated
R4362 T5133 T5129 arg3Of activated,reported
R4363 T5133 T5130 arg1Of activated,that
R4364 T5133 T5132 arg2Of activated,is
R4365 T5133 T5134 arg1Of activated,in
R4366 T5135 T5134 arg2Of brain,in
R4367 T5135 T5136 arg1Of brain,after
R4368 T5137 T5136 arg2Of TBI,after
R4369 T5137 T5138 arg1Of TBI,[
R4370 T5139 T5138 arg2Of 2,[
R4371 T5140 T5138 arg3Of ],[
R4372 T5143 T5144 arg1Of we,studied
R4373 T5144 T5141 arg1Of studied,Here
R4374 T5144 T5142 arg1Of studied,","
R4375 T5144 T5158 arg1Of studied,by
R4376 T5147 T5144 arg2Of activity,studied
R4377 T5147 T5145 arg1Of activity,the
R4378 T5147 T5146 arg1Of activity,DNA-binding
R4379 T5147 T5148 arg1Of activity,of
R4380 T5147 T5150 arg1Of activity,of
R4381 T5149 T5148 arg2Of NF-κB,of
R4382 T5151 T5150 arg2Of astrocytes,of
R4383 T5151 T5152 arg1Of astrocytes,from
R4384 T5154 T5153 arg1Of WT,Nrf2
R4385 T5154 T5155 arg1Of WT,or
R4386 T5155 T5152 arg2Of or,from
R4387 T5157 T5155 arg2Of mice,or
R4388 T5157 T5156 arg1Of mice,KO
R4389 T5159 T5158 arg2Of EMSA,by
R4390 T5159 T5160 arg1Of EMSA,at
R4391 T5162 T5160 arg2Of h,at
R4392 T5162 T5161 arg1Of h,24
R4393 T5162 T5163 arg1Of h,after
R4394 T5165 T5163 arg2Of injury,after
R4395 T5165 T5164 arg1Of injury,scratch
R4396 T5167 T5166 arg1Of injury,Scratch
R4397 T5167 T5168 arg1Of injury,induced
R4398 T5168 T5177 arg1Of induced,","
R4399 T5168 T5178 arg1Of induced,while
R4400 T5168 T5193 arg1Of induced,(
R4401 T5168 T5206 arg1Of induced,(
R4402 T5169 T5168 arg2Of activation,induced
R4403 T5169 T5170 arg1Of activation,of
R4404 T5169 T5172 arg1Of activation,in
R4405 T5171 T5170 arg2Of NF-κB,of
R4406 T5173 T5172 arg2Of astrocytes,in
R4407 T5173 T5174 arg1Of astrocytes,of
R4408 T5176 T5174 arg2Of genotypes,of
R4409 T5176 T5175 arg1Of genotypes,both
R4410 T5181 T5179 arg1Of activity,higher
R4411 T5181 T5180 arg1Of activity,NF-κB
R4412 T5181 T5182 arg1Of activity,was
R4413 T5181 T5183 arg2Of activity,observed
R4414 T5183 T5178 arg2Of observed,while
R4415 T5183 T5182 arg2Of observed,was
R4416 T5183 T5184 arg1Of observed,in
R4417 T5183 T5188 arg1Of observed,than
R4418 T5187 T5184 arg2Of TBI,in
R4419 T5187 T5185 arg1Of TBI,group
R4420 T5187 T5186 arg1Of TBI,KO
R4421 T5189 T5188 arg2Of in,than
R4422 T5192 T5189 arg2Of TBI,in
R4423 T5192 T5190 arg1Of TBI,group
R4424 T5192 T5191 arg1Of TBI,WT
R4425 T5196 T5197 arg1Of 0.173,versus
R4426 T5198 T5197 arg2Of 2.28,versus
R4427 T5198 T5199 arg1Of 2.28,±
R4428 T5200 T5193 arg2Of 0.072,(
R4429 T5200 T5194 arg1Of 0.072,2.67
R4430 T5200 T5195 arg1Of 0.072,±
R4431 T5200 T5196 arg1Of 0.072,0.173
R4432 T5200 T5201 arg1Of 0.072,","
R4433 T5202 T5201 arg2Of P,","
R4434 T5202 T5203 arg1Of P,<
R4435 T5202 T5204 arg1Of P,0.01
R4436 T5205 T5193 arg3Of ),(
R4437 T5207 T5206 arg2Of Figure,(
R4438 T5207 T5208 arg1Of Figure,2
R4439 T5209 T5206 arg3Of ),(
R451 T641 T640 arg1Of damage,Brain
R452 T641 T642 arg1Of damage,following
R453 T641 T645 arg1Of damage,is
R454 T644 T642 arg2Of injury,following
R455 T644 T643 arg1Of injury,traumatic
R456 T647 T645 arg2Of result,is
R457 T647 T646 arg1Of result,a
R4574 T5469 T5470 arg1Of Expression,of
R4575 T5469 T5473 arg1Of Expression,Was
R4576 T5469 T5474 arg2Of Expression,Elevated
R4577 T5472 T5470 arg2Of Cytokines,of
R4578 T5472 T5471 arg1Of Cytokines,Proinflammatory
R4579 T5474 T5473 arg2Of Elevated,Was
R458 T647 T648 arg1Of result,of
R4580 T5474 T5475 arg1Of Elevated,in
R4581 T5474 T5479 arg1Of Elevated,after
R4582 T5478 T5475 arg2Of Astrocytes,in
R4583 T5478 T5476 arg1Of Astrocytes,Nrf2
R4584 T5478 T5477 arg1Of Astrocytes,Knockout
R4585 T5481 T5479 arg2Of Injury,after
R4586 T5481 T5480 arg1Of Injury,Scratch
R4587 T5484 T5483 arg1Of all,we
R4588 T5484 T5485 arg1Of all,know
R4589 T5485 T5482 arg2Of know,As
R459 T649 T650 arg1Of direct,(
R4590 T5487 T5488 arg1Of TNF-α,","
R4591 T5488 T5491 arg1Of ",",and
R4592 T5489 T5488 arg2Of IL-1β,","
R4593 T5491 T5490 arg1Of and,","
R4594 T5491 T5493 arg1Of and,are
R4595 T5491 T5494 arg2Of and,regulated
R4596 T5491 T5498 arg1Of and,reflect
R4597 T5492 T5491 arg2Of IL-6,and
R4598 T5494 T5493 arg2Of regulated,are
R4599 T5494 T5497 arg1Of regulated,and
R460 T649 T654 arg1Of direct,and
R4600 T5496 T5494 arg1Of NF-κB,regulated
R4601 T5496 T5495 arg2Of NF-κB,by
R4602 T5497 T5482 arg1Of and,As
R4603 T5497 T5486 arg1Of and,","
R4604 T5498 T5497 arg2Of reflect,and
R4605 T5501 T5498 arg2Of activity,reflect
R4606 T5501 T5499 arg1Of activity,the
R4607 T5501 T5500 arg1Of activity,endogenous
R4608 T5501 T5502 arg1Of activity,of
R4609 T5503 T5502 arg2Of NF-κB,of
R461 T652 T650 arg2Of injury,(
R4610 T5504 T5505 arg1Of It,has
R4611 T5504 T5506 arg1Of It,been
R4612 T5504 T5507 arg2Of It,revealed
R4613 T5507 T5505 arg2Of revealed,has
R4614 T5507 T5506 arg2Of revealed,been
R4615 T5511 T5509 arg1Of cytokines,these
R4616 T5511 T5510 arg1Of cytokines,proinflammatory
R4617 T5511 T5512 arg1Of cytokines,are
R4618 T5511 T5513 arg2Of cytokines,increased
R4619 T5513 T5507 arg3Of increased,revealed
R462 T652 T651 arg1Of injury,primary
R4620 T5513 T5508 arg1Of increased,that
R4621 T5513 T5512 arg2Of increased,are
R4622 T5513 T5514 arg1Of increased,after
R4623 T5515 T5514 arg2Of TBI,after
R4624 T5515 T5516 arg1Of TBI,in
R4625 T5517 T5516 arg2Of animals,in
R4626 T5517 T5518 arg1Of animals,[
R4627 T5519 T5518 arg2Of 2,[
R4628 T5519 T5520 arg1Of 2,","
R4629 T5521 T5520 arg2Of 8,","
R463 T653 T650 arg3Of ),(
R4630 T5522 T5518 arg3Of ],[
R4631 T5526 T5524 arg1Of study,our
R4632 T5526 T5525 arg1Of study,previous
R4633 T5526 T5527 arg1Of study,has
R4634 T5526 T5528 arg1Of study,proved
R4635 T5528 T5523 arg1Of proved,And
R4636 T5528 T5527 arg2Of proved,has
R4637 T5531 T5530 arg1Of levels,higher
R4638 T5531 T5532 arg1Of levels,of
R4639 T5531 T5536 arg1Of levels,were
R464 T655 T654 arg2Of indirect,and
R4640 T5531 T5537 arg2Of levels,observed
R4641 T5535 T5532 arg2Of cytokines,of
R4642 T5535 T5533 arg1Of cytokines,such
R4643 T5535 T5534 arg1Of cytokines,proinflammatory
R4644 T5537 T5528 arg2Of observed,proved
R4645 T5537 T5529 arg1Of observed,that
R4646 T5537 T5536 arg2Of observed,were
R4647 T5537 T5538 arg1Of observed,in
R4648 T5540 T5538 arg2Of brain,in
R4649 T5540 T5539 arg1Of brain,the
R465 T655 T656 arg1Of indirect,(
R4650 T5540 T5541 arg1Of brain,of
R4651 T5540 T5544 arg1Of brain,after
R4652 T5543 T5541 arg2Of mice,of
R4653 T5543 T5542 arg1Of mice,Nrf2-deficient
R4654 T5545 T5544 arg2Of TBI,after
R4655 T5545 T5546 arg1Of TBI,[
R4656 T5547 T5546 arg2Of 5,[
R4657 T5548 T5546 arg3Of ],[
R4658 T5550 T5551 arg1Of it,is
R4659 T5550 T5553 arg1Of it,ambiguous
R466 T660 T656 arg2Of injury,(
R4660 T5551 T5549 arg1Of is,But
R4661 T5551 T5552 arg1Of is,still
R4662 T5553 T5551 arg2Of ambiguous,is
R4663 T5553 T5554 arg1Of ambiguous,about
R4664 T5556 T5554 arg2Of relationship,about
R4665 T5556 T5555 arg1Of relationship,the
R4666 T5556 T5557 arg1Of relationship,between
R4667 T5559 T5560 arg1Of cytokines,and
R4668 T5560 T5557 arg2Of and,between
R4669 T5560 T5558 arg1Of and,these
R467 T660 T657 arg1Of injury,secondary
R4670 T5560 T5562 arg1Of and,in
R4671 T5561 T5560 arg2Of Nrf2,and
R4672 T5563 T5562 arg2Of astrocytes,in
R4673 T5563 T5564 arg1Of astrocytes,after
R4674 T5565 T5564 arg2Of TBI,after
R4675 T5568 T5569 arg1Of we,tested
R4676 T5569 T5566 arg1Of tested,Here
R4677 T5569 T5567 arg1Of tested,","
R4678 T5569 T5582 arg1Of tested,at
R4679 T5571 T5569 arg2Of levels,tested
R468 T660 T658 arg1Of injury,or
R4680 T5571 T5570 arg1Of levels,the
R4681 T5571 T5572 arg1Of levels,of
R4682 T5573 T5574 arg1Of TNF-α,","
R4683 T5574 T5577 arg1Of ",",and
R4684 T5575 T5574 arg2Of IL-1β,","
R4685 T5577 T5572 arg2Of and,of
R4686 T5577 T5576 arg1Of and,","
R4687 T5577 T5579 arg1Of and,in
R4688 T5578 T5577 arg2Of IL-6,and
R4689 T5581 T5579 arg2Of astrocytes,in
R469 T660 T659 arg2Of injury,delayed
R4690 T5581 T5580 arg2Of astrocytes,cultured
R4691 T5584 T5582 arg2Of h,at
R4692 T5584 T5583 arg1Of h,24
R4693 T5584 T5585 arg1Of h,after
R4694 T5587 T5585 arg2Of injury,after
R4695 T5587 T5586 arg1Of injury,scratch
R4696 T5587 T5588 arg1Of injury,by
R4697 T5589 T5590 arg1Of RT-PCR,and
R4698 T5590 T5588 arg2Of and,by
R4699 T5591 T5590 arg2Of ELISA,and
R470 T661 T656 arg3Of ),(
R4700 T5592 T5593 arg1Of It,was
R4701 T5592 T5594 arg2Of It,shown
R4702 T5594 T5593 arg2Of shown,was
R4703 T5594 T5622 arg1Of shown,","
R4704 T5594 T5623 arg1Of shown,respectively
R4705 T5598 T5596 arg1Of levels,the
R4706 T5598 T5597 arg1Of levels,mRNA
R4707 T5598 T5599 arg1Of levels,of
R4708 T5598 T5606 arg1Of levels,were
R4709 T5598 T5607 arg2Of levels,increased
R471 T662 T648 arg2Of mechanisms,of
R4710 T5598 T5617 arg1Of levels,compared
R4711 T5600 T5601 arg1Of TNF-α,","
R4712 T5601 T5604 arg1Of ",",and
R4713 T5602 T5601 arg2Of IL-1β,","
R4714 T5604 T5599 arg2Of and,of
R4715 T5604 T5603 arg1Of and,","
R4716 T5605 T5604 arg2Of IL-6,and
R4717 T5607 T5594 arg3Of increased,shown
R4718 T5607 T5595 arg1Of increased,that
R4719 T5607 T5606 arg2Of increased,were
R472 T662 T649 arg1Of mechanisms,direct
R4720 T5607 T5608 arg1Of increased,after
R4721 T5607 T5610 arg1Of increased,in
R4722 T5607 T5616 arg1Of increased,when
R4723 T5609 T5608 arg2Of scratch,after
R4724 T5612 T5613 arg1Of WT,and
R4725 T5614 T5613 arg2Of KO,and
R4726 T5615 T5610 arg2Of astrocytes,in
R4727 T5615 T5611 arg1Of astrocytes,both
R4728 T5615 T5612 arg1Of astrocytes,WT
R4729 T5615 T5614 arg1Of astrocytes,KO
R473 T662 T655 arg1Of mechanisms,indirect
R4730 T5617 T5616 arg2Of compared,when
R4731 T5617 T5618 arg1Of compared,with
R4732 T5621 T5618 arg2Of counterparts,with
R4733 T5621 T5619 arg1Of counterparts,their
R4734 T5621 T5620 arg1Of counterparts,sham
R4735 T5628 T5626 arg1Of levels,the
R4736 T5628 T5627 arg1Of levels,mRNA
R4737 T5628 T5629 arg1Of levels,of
R4738 T5628 T5636 arg1Of levels,were
R4739 T5628 T5638 arg1Of levels,higher
R474 T666 T663 arg1Of mechanism,The
R4740 T5631 T5629 arg2Of cytokines,of
R4741 T5631 T5630 arg1Of cytokines,these
R4742 T5631 T5632 arg1Of cytokines,in
R4743 T5635 T5632 arg2Of TBI,in
R4744 T5635 T5633 arg1Of TBI,group
R4745 T5635 T5634 arg1Of TBI,KO
R4746 T5636 T5624 arg1Of were,Moreover
R4747 T5636 T5625 arg1Of were,","
R4748 T5636 T5652 arg1Of were,0.110
R4749 T5638 T5636 arg2Of higher,were
R475 T666 T664 arg1Of mechanism,secondary
R4750 T5638 T5637 arg1Of higher,much
R4751 T5638 T5639 arg1Of higher,than
R4752 T5638 T5648 arg1Of higher,0.085
R4753 T5640 T5639 arg2Of those,than
R4754 T5640 T5641 arg1Of those,in
R4755 T5644 T5641 arg2Of TBI,in
R4756 T5644 T5642 arg1Of TBI,group
R4757 T5644 T5643 arg1Of TBI,WT
R4758 T5648 T5645 arg1Of 0.085,(
R4759 T5648 T5646 arg1Of 0.085,1.66
R476 T666 T665 arg1Of mechanism,injury
R4760 T5648 T5647 arg1Of 0.085,±
R4761 T5648 T5649 arg1Of 0.085,versus
R4762 T5650 T5649 arg2Of 1.39,versus
R4763 T5650 T5651 arg1Of 1.39,±
R4764 T5652 T5653 arg1Of 0.110,for
R4765 T5654 T5655 arg1Of TNF-α,","
R4766 T5654 T5666 arg1Of TNF-α,and
R4767 T5658 T5659 arg1Of 0.064,versus
R4768 T5658 T5661 arg1Of 0.064,±
R4769 T5660 T5659 arg2Of 0.73,versus
R477 T666 T667 arg1Of mechanism,involves
R4770 T5662 T5655 arg2Of 0.088,","
R4771 T5662 T5656 arg1Of 0.088,1.34
R4772 T5662 T5657 arg1Of 0.088,±
R4773 T5662 T5658 arg1Of 0.088,0.064
R4774 T5662 T5663 arg1Of 0.088,for
R4775 T5664 T5663 arg2Of IL-1β,for
R4776 T5666 T5653 arg2Of and,for
R4777 T5666 T5665 arg1Of and,","
R4778 T5669 T5670 arg1Of 0.102,versus
R4779 T5669 T5672 arg1Of 0.102,±
R478 T669 T667 arg2Of initiation,involves
R4780 T5671 T5670 arg2Of 0.99,versus
R4781 T5673 T5666 arg2Of 0.073,and
R4782 T5673 T5667 arg1Of 0.073,1.28
R4783 T5673 T5668 arg1Of 0.073,±
R4784 T5673 T5669 arg1Of 0.073,0.102
R4785 T5673 T5674 arg1Of 0.073,for
R4786 T5675 T5674 arg2Of IL-6,for
R4787 T5676 T5677 arg1Of P,<
R4788 T5676 T5678 arg1Of P,0.01
R4789 T5678 T5679 arg1Of 0.01,)
R479 T669 T668 arg1Of initiation,the
R4790 T5678 T5680 arg1Of 0.01,(
R4791 T5682 T5680 arg2Of 3,(
R4792 T5682 T5681 arg1Of 3,Figures
R4793 T5682 T5683 arg1Of 3,(
R4794 T5688 T5683 arg2Of d,(
R4795 T5688 T5684 arg1Of d,a
R4796 T5688 T5685 arg1Of d,)
R4797 T5688 T5686 arg1Of d,–3
R4798 T5688 T5687 arg1Of d,(
R4799 T5689 T5683 arg3Of ),(
R480 T669 T670 arg1Of initiation,of
R4800 T5690 T5680 arg3Of ),(
R4801 T5692 T5691 arg1Of results,The
R4802 T5692 T5693 arg1Of results,of
R4803 T5692 T5695 arg1Of results,revealed
R4804 T5694 T5693 arg2Of ELISA,of
R4805 T5699 T5697 arg1Of level,the
R4806 T5699 T5698 arg1Of level,protein
R4807 T5699 T5700 arg1Of level,of
R4808 T5699 T5702 arg1Of level,was
R4809 T5699 T5703 arg2Of level,upregulated
R481 T669 T675 arg1Of initiation,","
R4810 T5699 T5713 arg1Of level,compared
R4811 T5701 T5700 arg2Of TNF-α,of
R4812 T5703 T5695 arg2Of upregulated,revealed
R4813 T5703 T5696 arg1Of upregulated,that
R4814 T5703 T5702 arg2Of upregulated,was
R4815 T5703 T5704 arg1Of upregulated,after
R4816 T5703 T5712 arg1Of upregulated,when
R4817 T5706 T5704 arg2Of injury,after
R4818 T5706 T5705 arg1Of injury,scratch
R4819 T5706 T5707 arg1Of injury,in
R482 T669 T676 arg1Of initiation,including
R4820 T5708 T5709 arg1Of WT,and
R4821 T5710 T5709 arg2Of KO,and
R4822 T5711 T5707 arg2Of astrocytes,in
R4823 T5711 T5708 arg1Of astrocytes,WT
R4824 T5711 T5710 arg1Of astrocytes,KO
R4825 T5713 T5712 arg2Of compared,when
R4826 T5713 T5714 arg1Of compared,with
R4827 T5717 T5714 arg2Of counterparts,with
R4828 T5717 T5715 arg1Of counterparts,their
R4829 T5717 T5716 arg1Of counterparts,sham
R483 T674 T670 arg2Of response,of
R4830 T5719 T5720 arg1Of it,was
R4831 T5719 T5722 arg1Of it,higher
R4832 T5720 T5718 arg1Of was,And
R4833 T5720 T5721 arg1Of was,also
R4834 T5720 T5732 arg1Of was,(
R4835 T5720 T5745 arg1Of was,(
R4836 T5720 T5751 arg1Of was,)
R4837 T5722 T5720 arg2Of higher,was
R4838 T5722 T5723 arg1Of higher,in
R4839 T5722 T5727 arg1Of higher,than
R484 T674 T671 arg1Of response,an
R4840 T5726 T5723 arg2Of TBI,in
R4841 T5726 T5724 arg1Of TBI,group
R4842 T5726 T5725 arg1Of TBI,KO
R4843 T5728 T5727 arg2Of in,than
R4844 T5731 T5728 arg2Of TBI,in
R4845 T5731 T5729 arg1Of TBI,group
R4846 T5731 T5730 arg1Of TBI,WT
R4847 T5735 T5736 arg1Of 0.156,versus
R4848 T5737 T5736 arg2Of 2.31,versus
R4849 T5737 T5738 arg1Of 2.31,±
R485 T674 T672 arg1Of response,acute
R4850 T5739 T5732 arg2Of 0.087,(
R4851 T5739 T5733 arg1Of 0.087,3.67
R4852 T5739 T5734 arg1Of 0.087,±
R4853 T5739 T5735 arg1Of 0.087,0.156
R4854 T5739 T5740 arg1Of 0.087,","
R4855 T5741 T5740 arg2Of P,","
R4856 T5741 T5742 arg1Of P,<
R4857 T5741 T5743 arg1Of P,0.01
R4858 T5744 T5732 arg3Of ),(
R4859 T5746 T5745 arg2Of Figure,(
R486 T674 T673 arg1Of response,inflammatory
R4860 T5746 T5747 arg1Of Figure,4
R4861 T5746 T5748 arg1Of Figure,(
R4862 T5746 T5749 arg1Of Figure,a
R4863 T5750 T5745 arg3Of ),(
R4864 T5753 T5752 arg1Of tendency,Similar
R4865 T5753 T5754 arg1Of tendency,was
R4866 T5753 T5755 arg2Of tendency,observed
R4867 T5755 T5754 arg2Of observed,was
R4868 T5755 T5756 arg1Of observed,in
R4869 T5758 T5756 arg2Of level,in
R487 T677 T676 arg2Of breakdown,including
R4870 T5758 T5757 arg1Of level,protein
R4871 T5758 T5759 arg1Of level,of
R4872 T5760 T5761 arg1Of IL-6,and
R4873 T5761 T5759 arg2Of and,of
R4874 T5762 T5761 arg2Of IL-1β,and
R4875 T5764 T5763 arg2Of IL-6,For
R4876 T5766 T5767 arg1Of it,was
R4877 T5767 T5763 arg1Of was,For
R4878 T5767 T5765 arg1Of was,","
R4879 T5767 T5775 arg1Of was,while
R488 T677 T678 arg1Of breakdown,of
R4880 T5770 T5767 arg2Of 0.786,was
R4881 T5770 T5768 arg1Of 0.786,36.07
R4882 T5770 T5769 arg1Of 0.786,±
R4883 T5770 T5771 arg1Of 0.786,for
R4884 T5774 T5771 arg2Of TBI,for
R4885 T5774 T5772 arg1Of TBI,group
R4886 T5774 T5773 arg1Of TBI,KO
R4887 T5778 T5775 arg2Of 0.536,while
R4888 T5778 T5776 arg1Of 0.536,25.76
R4889 T5778 T5777 arg1Of 0.536,±
R489 T680 T679 arg1Of barrier,blood-brain
R4890 T5778 T5779 arg1Of 0.536,for
R4891 T5778 T5788 arg1Of 0.536,(
R4892 T5782 T5779 arg2Of TBI,for
R4893 T5782 T5780 arg1Of TBI,group
R4894 T5782 T5781 arg1Of TBI,WT
R4895 T5782 T5783 arg1Of TBI,(
R4896 T5784 T5783 arg2Of P,(
R4897 T5784 T5785 arg1Of P,<
R4898 T5784 T5786 arg1Of P,0.01
R4899 T5787 T5783 arg3Of ),(
R490 T680 T681 arg1Of barrier,(
R4900 T5789 T5788 arg2Of Figure,(
R4901 T5789 T5790 arg1Of Figure,4
R4902 T5789 T5791 arg1Of Figure,(
R4903 T5792 T5791 arg2Of b,(
R4904 T5793 T5791 arg3Of ),(
R4905 T5794 T5788 arg3Of ),(
R4906 T5796 T5795 arg2Of IL-1β,For
R4907 T5798 T5799 arg1Of it,was
R4908 T5799 T5795 arg1Of was,For
R4909 T5799 T5797 arg1Of was,","
R491 T680 T684 arg1Of barrier,","
R4910 T5799 T5807 arg1Of was,while
R4911 T5802 T5799 arg2Of 6.339,was
R4912 T5802 T5800 arg1Of 6.339,190.75
R4913 T5802 T5801 arg1Of 6.339,±
R4914 T5802 T5803 arg1Of 6.339,for
R4915 T5806 T5803 arg2Of TBI,for
R4916 T5806 T5804 arg1Of TBI,group
R4917 T5806 T5805 arg1Of TBI,KO
R4918 T5810 T5807 arg2Of 5.348,while
R4919 T5810 T5808 arg1Of 5.348,154.50
R492 T682 T681 arg2Of BBB,(
R4920 T5810 T5809 arg1Of 5.348,±
R4921 T5810 T5811 arg1Of 5.348,for
R4922 T5810 T5820 arg1Of 5.348,(
R4923 T5814 T5811 arg2Of TBI,for
R4924 T5814 T5812 arg1Of TBI,group
R4925 T5814 T5813 arg1Of TBI,WT
R4926 T5814 T5815 arg1Of TBI,(
R4927 T5816 T5815 arg2Of P,(
R4928 T5816 T5817 arg1Of P,<
R4929 T5816 T5818 arg1Of P,0.01
R493 T683 T681 arg3Of ),(
R4930 T5819 T5815 arg3Of ),(
R4931 T5821 T5820 arg2Of Figure,(
R4932 T5821 T5822 arg1Of Figure,4
R4933 T5821 T5823 arg1Of Figure,(
R4934 T5824 T5823 arg2Of c,(
R4935 T5825 T5823 arg3Of ),(
R4936 T5826 T5820 arg3Of ),(
R494 T684 T687 arg1Of ",",","
R495 T686 T684 arg2Of edema,","
R496 T686 T685 arg1Of edema,brain
R497 T687 T694 arg1Of ",",and
R498 T688 T687 arg2Of infiltration,","
R499 T688 T689 arg1Of infiltration,of
R500 T692 T689 arg2Of cells,of
R501 T692 T690 arg1Of cells,peripheral
R502 T692 T691 arg1Of cells,blood
R503 T694 T693 arg1Of and,","
R504 T694 T703 arg1Of and,as
R505 T695 T694 arg2Of activation,and
R506 T695 T696 arg1Of activation,of
R507 T699 T696 arg2Of cells,of
R508 T699 T697 arg1Of cells,resident
R509 T699 T698 arg1Of cells,immunocompetent
R510 T703 T678 arg2Of as,of
R511 T703 T700 arg1Of as,","
R512 T703 T701 arg1Of as,as
R513 T703 T702 arg1Of as,well
R514 T705 T703 arg2Of release,as
R515 T705 T704 arg1Of release,the
R516 T705 T706 arg1Of release,of
R517 T709 T706 arg2Of mediators,of
R518 T709 T707 arg1Of mediators,numerous
R519 T709 T708 arg1Of mediators,immune
R520 T709 T711 arg1Of mediators,as
R521 T711 T710 arg1Of as,such
R522 T712 T713 arg1Of interleukins,and
R523 T713 T711 arg2Of and,as
R524 T715 T713 arg2Of factors,and
R525 T715 T714 arg1Of factors,chemotactic
R526 T715 T716 arg1Of factors,[
R527 T717 T716 arg2Of 1,[
R528 T718 T716 arg3Of ],[
R529 T722 T720 arg1Of inflammation,the
R530 T722 T721 arg1Of inflammation,subsequent
R531 T722 T723 arg1Of inflammation,leads
R532 T723 T719 arg1Of leads,And
R533 T723 T724 arg1Of leads,to
R534 T723 T729 arg1Of leads,in
R535 T723 T733 arg1Of leads,in
R536 T726 T724 arg2Of damage,to
R537 T726 T725 arg1Of damage,secondary
R538 T728 T727 arg1Of only,not
R5381 T6504 T6505 arg1Of Expression,and
R5382 T6505 T6507 arg1Of and,of
R5383 T6505 T6509 arg1Of and,Were
R5384 T6505 T6511 arg2Of and,Enhanced
R5385 T6506 T6505 arg2Of Activity,and
R5386 T6508 T6507 arg2Of MMP9,of
R5387 T6511 T6509 arg2Of Enhanced,Were
R5388 T6511 T6510 arg1Of Enhanced,Greatly
R5389 T6511 T6512 arg1Of Enhanced,in
R539 T729 T731 arg1Of in,but
R5390 T6511 T6516 arg1Of Enhanced,after
R5391 T6515 T6512 arg2Of Astrocytes,in
R5392 T6515 T6513 arg1Of Astrocytes,Nrf2
R5393 T6515 T6514 arg1Of Astrocytes,Knockout
R5394 T6518 T6516 arg2Of Injury,after
R5395 T6518 T6517 arg1Of Injury,Scratch
R5396 T6519 T6520 arg1Of MMP9,is
R5397 T6523 T6520 arg2Of gelatinase,is
R5398 T6523 T6521 arg1Of gelatinase,an
R5399 T6523 T6522 arg1Of gelatinase,important
R540 T730 T729 arg2Of brain,in
R5400 T6523 T6524 modOf gelatinase,to
R5401 T6525 T6526 arg1Of induce,or
R5402 T6526 T6524 arg1Of or,to
R5403 T6527 T6526 arg2Of aggravate,or
R5404 T6530 T6525 arg2Of process,induce
R5405 T6530 T6527 arg2Of process,aggravate
R5406 T6530 T6528 arg1Of process,the
R5407 T6530 T6529 arg1Of process,inflammation
R5408 T6534 T6531 arg2Of study,In
R5409 T6534 T6532 arg1Of study,the
R541 T731 T728 arg1Of but,only
R5410 T6534 T6533 arg1Of study,present
R5411 T6536 T6537 arg1Of we,elevated
R5412 T6537 T6531 arg1Of elevated,In
R5413 T6537 T6535 arg1Of elevated,","
R5414 T6539 T6538 arg1Of mRNA,the
R5415 T6539 T6540 arg1Of mRNA,","
R5416 T6540 T6544 arg1Of ",",and
R5417 T6542 T6540 arg2Of levels,","
R5418 T6542 T6541 arg1Of levels,protein
R5419 T6544 T6537 arg2Of and,elevated
R542 T731 T732 arg1Of but,also
R5420 T6544 T6543 arg1Of and,","
R5421 T6545 T6544 arg2Of activity,and
R5422 T6545 T6546 arg1Of activity,of
R5423 T6547 T6546 arg2Of MMP9,of
R5424 T6547 T6548 arg1Of MMP9,in
R5425 T6549 T6548 arg2Of astrocytes,in
R5426 T6549 T6550 arg1Of astrocytes,at
R5427 T6549 T6553 arg1Of astrocytes,after
R5428 T6552 T6550 arg2Of h,at
R5429 T6552 T6551 arg1Of h,24
R543 T733 T731 arg2Of in,but
R5430 T6555 T6553 arg2Of injury,after
R5431 T6555 T6554 arg1Of injury,scratch
R5432 T6555 T6556 arg1Of injury,by
R5433 T6557 T6558 arg1Of RT-PCR,","
R5434 T6558 T6562 arg1Of ",",and
R5435 T6560 T6558 arg2Of blot,","
R5436 T6560 T6559 arg1Of blot,western
R5437 T6562 T6556 arg2Of and,by
R5438 T6562 T6561 arg1Of and,","
R5439 T6564 T6562 arg2Of zymography,and
R544 T735 T729 arg3Of organs,in
R5440 T6564 T6563 arg1Of zymography,gelatine
R5441 T6565 T6566 arg1Of Expression,of
R5442 T6565 T6568 arg1Of Expression,was
R5443 T6565 T6569 arg2Of Expression,elevated
R5444 T6567 T6566 arg2Of MMP9,of
R5445 T6569 T6568 arg2Of elevated,was
R5446 T6569 T6570 arg1Of elevated,after
R5447 T6572 T6570 arg2Of injury,after
R5448 T6572 T6571 arg1Of injury,scratch
R5449 T6572 T6573 arg1Of injury,in
R545 T735 T733 arg2Of organs,in
R5450 T6572 T6578 arg1Of injury,as
R5451 T6574 T6575 arg1Of WT,and
R5452 T6576 T6575 arg2Of KO,and
R5453 T6577 T6573 arg2Of astrocytes,in
R5454 T6577 T6574 arg1Of astrocytes,WT
R5455 T6577 T6576 arg1Of astrocytes,KO
R5456 T6579 T6578 arg2Of compared,as
R5457 T6579 T6580 arg1Of compared,with
R5458 T6583 T6580 arg2Of counterparts,with
R5459 T6583 T6581 arg1Of counterparts,their
R546 T735 T734 arg1Of organs,other
R5460 T6583 T6582 arg1Of counterparts,sham
R5461 T6586 T6584 arg1Of level,The
R5462 T6586 T6585 arg1Of level,mRNA
R5463 T6586 T6587 arg1Of level,of
R5464 T6586 T6589 arg1Of level,was
R5465 T6586 T6590 arg1Of level,higher
R5466 T6588 T6587 arg2Of MMP9,of
R5467 T6589 T6600 arg1Of was,(
R5468 T6589 T6613 arg1Of was,(
R5469 T6590 T6589 arg2Of higher,was
R547 T735 T736 arg1Of organs,[
R5470 T6590 T6591 arg1Of higher,in
R5471 T6590 T6595 arg1Of higher,than
R5472 T6594 T6591 arg2Of TBI,in
R5473 T6594 T6592 arg1Of TBI,group
R5474 T6594 T6593 arg1Of TBI,KO
R5475 T6596 T6595 arg2Of in,than
R5476 T6599 T6596 arg2Of TBI,in
R5477 T6599 T6597 arg1Of TBI,group
R5478 T6599 T6598 arg1Of TBI,WT
R5479 T6603 T6604 arg1Of 0.090,versus
R548 T737 T736 arg2Of 2–4,[
R5480 T6605 T6604 arg2Of 1.01,versus
R5481 T6605 T6606 arg1Of 1.01,±
R5482 T6607 T6600 arg2Of 0.068,(
R5483 T6607 T6601 arg1Of 0.068,1.36
R5484 T6607 T6602 arg1Of 0.068,±
R5485 T6607 T6603 arg1Of 0.068,0.090
R5486 T6607 T6608 arg1Of 0.068,","
R5487 T6609 T6608 arg2Of P,","
R5488 T6609 T6610 arg1Of P,<
R5489 T6609 T6611 arg1Of P,0.01
R549 T738 T736 arg3Of ],[
R5490 T6612 T6600 arg3Of ),(
R5491 T6615 T6614 arg1Of 3,Figures
R5492 T6615 T6616 arg1Of 3,(
R5493 T6615 T6617 arg1Of 3,a
R5494 T6615 T6618 arg1Of 3,)
R5495 T6615 T6619 arg1Of 3,and
R5496 T6619 T6613 arg2Of and,(
R5497 T6620 T6619 arg2Of 3,and
R5498 T6620 T6621 arg1Of 3,(
R5499 T6622 T6621 arg2Of e,(
R550 T741 T739 arg1Of erythroid,Nuclear
R5500 T6623 T6621 arg3Of ),(
R5501 T6624 T6613 arg3Of ),(
R5502 T6626 T6625 arg1Of difference,Significant
R5503 T6626 T6627 arg1Of difference,was
R5504 T6626 T6629 arg2Of difference,discovered
R5505 T6629 T6627 arg2Of discovered,was
R5506 T6629 T6628 arg1Of discovered,also
R5507 T6629 T6630 arg1Of discovered,in
R5508 T6629 T6637 arg1Of discovered,","
R5509 T6629 T6638 arg1Of discovered,as
R551 T741 T740 arg1Of erythroid,factor
R5510 T6633 T6630 arg2Of level,in
R5511 T6633 T6631 arg1Of level,MMP9
R5512 T6633 T6632 arg1Of level,protein
R5513 T6636 T6629 arg1Of blot,discovered
R5514 T6636 T6634 arg2Of blot,by
R5515 T6636 T6635 arg1Of blot,western
R5516 T6641 T6638 arg2Of 0.076,as
R5517 T6641 T6639 arg1Of 0.076,1.44
R5518 T6641 T6640 arg1Of 0.076,±
R5519 T6641 T6642 arg1Of 0.076,for
R552 T743 T741 arg1Of factor2,erythroid
R5520 T6645 T6643 arg1Of TBI,group
R5521 T6645 T6644 arg1Of TBI,KO
R5522 T6645 T6646 arg1Of TBI,and
R5523 T6646 T6642 arg2Of and,for
R5524 T6647 T6648 arg1Of 1.13,±
R5525 T6649 T6646 arg2Of 0.048,and
R5526 T6649 T6647 arg1Of 0.048,1.13
R5527 T6649 T6650 arg1Of 0.048,for
R5528 T6649 T6659 arg1Of 0.048,(
R5529 T6653 T6650 arg2Of TBI,for
R553 T743 T742 arg1Of factor2,2-related
R5530 T6653 T6651 arg1Of TBI,group
R5531 T6653 T6652 arg1Of TBI,WT
R5532 T6653 T6654 arg1Of TBI,(
R5533 T6655 T6654 arg2Of P,(
R5534 T6655 T6656 arg1Of P,<
R5535 T6655 T6657 arg1Of P,0.01
R5536 T6658 T6654 arg3Of ),(
R5537 T6660 T6659 arg2Of Figure,(
R5538 T6660 T6661 arg1Of Figure,5
R5539 T6662 T6659 arg3Of ),(
R554 T743 T744 arg1Of factor2,(
R5540 T6664 T6663 arg1Of zymography,Gelatine
R5541 T6664 T6665 arg1Of zymography,revealed
R5542 T6668 T6665 arg2Of activity,revealed
R5543 T6668 T6666 arg1Of activity,higher
R5544 T6668 T6667 arg1Of activity,MMP9
R5545 T6668 T6669 arg1Of activity,in
R5546 T6668 T6673 arg1Of activity,than
R5547 T6668 T6679 arg1Of activity,too
R5548 T6668 T6693 arg1Of activity,(
R5549 T6672 T6669 arg2Of TBI,in
R555 T743 T747 arg1Of factor2,is
R5550 T6672 T6670 arg1Of TBI,group
R5551 T6672 T6671 arg1Of TBI,KO
R5552 T6674 T6673 arg2Of that,than
R5553 T6674 T6675 arg1Of that,in
R5554 T6678 T6675 arg2Of TBI,in
R5555 T6678 T6676 arg1Of TBI,group
R5556 T6678 T6677 arg1Of TBI,WT
R5557 T6679 T6680 arg1Of too,(
R5558 T6683 T6684 arg1Of 6.343,versus
R5559 T6685 T6684 arg2Of 76.32,versus
R556 T745 T744 arg2Of Nrf2,(
R5560 T6685 T6686 arg1Of 76.32,±
R5561 T6687 T6680 arg2Of 3.388,(
R5562 T6687 T6681 arg1Of 3.388,101.76
R5563 T6687 T6682 arg1Of 3.388,±
R5564 T6687 T6683 arg1Of 3.388,6.343
R5565 T6687 T6688 arg1Of 3.388,","
R5566 T6689 T6688 arg2Of P,","
R5567 T6689 T6690 arg1Of P,<
R5568 T6689 T6691 arg1Of P,0.01
R5569 T6692 T6680 arg3Of ),(
R557 T746 T744 arg3Of ),(
R5570 T6694 T6693 arg2Of Figure,(
R5571 T6694 T6695 arg1Of Figure,6
R5572 T6696 T6693 arg3Of ),(
R558 T750 T747 arg2Of factor,is
R559 T750 T748 arg1Of factor,a
R560 T750 T749 arg1Of factor,transcription
R561 T750 T751 arg1Of factor,that
R562 T750 T752 arg1Of factor,regulates
R563 T754 T752 arg2Of kinds,regulates
R564 T754 T753 arg1Of kinds,many
R565 T754 T755 arg1Of kinds,of
R566 T757 T755 arg2Of genes,of
R567 T757 T756 arg1Of genes,antioxidant
R568 T759 T758 arg1Of studies,Several
R569 T759 T760 arg1Of studies,have
R570 T759 T761 arg1Of studies,demonstrated
R571 T761 T760 arg2Of demonstrated,have
R572 T763 T764 arg1Of Nrf2,regulates
R573 T764 T761 arg2Of regulates,demonstrated
R574 T764 T762 arg1Of regulates,that
R575 T764 T767 arg1Of regulates,in
R576 T764 T770 arg1Of regulates,after
R577 T766 T764 arg2Of inflammation,regulates
R578 T766 T765 arg1Of inflammation,the
R579 T769 T767 arg2Of brain,in
R580 T769 T768 arg1Of brain,the
R581 T773 T770 arg2Of injury,after
R582 T773 T771 arg1Of injury,traumatic
R583 T773 T772 arg1Of injury,brain
R584 T773 T774 arg1Of injury,(
R585 T775 T774 arg2Of TBI,(
R586 T776 T774 arg3Of ),(
R587 T780 T779 arg1Of showed,also
R588 T782 T783 arg1Of TBI,could
R589 T782 T784 arg1Of TBI,induce
R590 T784 T780 arg2Of induce,showed
R5909 T7370 T7368 arg1Of study,The
R591 T784 T781 arg1Of induce,that
R5910 T7370 T7369 arg1Of study,present
R5911 T7370 T7371 arg1Of study,demonstrated
R5912 T7374 T7373 arg1Of injury,scratch
R5913 T7374 T7375 arg1Of injury,induced
R5914 T7375 T7371 arg2Of induced,demonstrated
R5915 T7375 T7372 arg1Of induced,that
R5916 T7377 T7376 arg1Of upregulation,the
R5917 T7377 T7378 arg1Of upregulation,of
R5918 T7377 T7383 arg1Of upregulation,and
R5919 T7382 T7378 arg2Of activity,of
R592 T784 T783 arg2Of induce,could
R5920 T7382 T7379 arg1Of activity,NF-κB
R5921 T7382 T7380 arg1Of activity,DNA
R5922 T7382 T7381 arg1Of activity,binding
R5923 T7383 T7375 arg2Of and,induced
R5924 T7384 T7383 arg2Of overexpression,and
R5925 T7384 T7385 arg1Of overexpression,of
R5926 T7386 T7387 arg1Of TNF-α,","
R5927 T7387 T7389 arg1Of ",",","
R5928 T7388 T7387 arg2Of IL-1β,","
R5929 T7389 T7392 arg1Of ",",and
R593 T784 T792 arg1Of induce,than
R5930 T7390 T7389 arg2Of IL-6,","
R5931 T7392 T7385 arg2Of and,of
R5932 T7392 T7391 arg1Of and,","
R5933 T7392 T7394 arg1Of and,in
R5934 T7393 T7392 arg2Of MMP9,and
R5935 T7396 T7394 arg2Of astrocytes,in
R5936 T7396 T7395 arg2Of astrocytes,cultured
R5937 T7398 T7399 arg1Of we,revealed
R5938 T7399 T7397 arg1Of revealed,Also
R5939 T7402 T7401 arg1Of injury,scratch
R594 T784 T796 arg1Of induce,[
R5940 T7402 T7403 arg1Of injury,induced
R5941 T7403 T7399 arg2Of induced,revealed
R5942 T7403 T7400 arg1Of induced,that
R5943 T7405 T7404 arg1Of activity,higher
R5944 T7405 T7406 arg1Of activity,of
R5945 T7405 T7408 arg1Of activity,and
R5946 T7407 T7406 arg2Of NF-κB,of
R5947 T7408 T7403 arg2Of and,induced
R5948 T7410 T7408 arg2Of expression,and
R5949 T7410 T7409 arg2Of expression,enhanced
R595 T786 T785 arg1Of aggravated,more
R5950 T7410 T7411 arg1Of expression,of
R5951 T7410 T7414 arg1Of expression,in
R5952 T7413 T7411 arg2Of cytokines,of
R5953 T7413 T7412 arg1Of cytokines,proinflammatory
R5954 T7418 T7414 arg2Of astrocytes,in
R5955 T7418 T7415 arg1Of astrocytes,Nrf2
R5956 T7418 T7416 arg1Of astrocytes,knockout
R5957 T7418 T7417 arg2Of astrocytes,cultured
R5958 T7418 T7419 arg1Of astrocytes,than
R5959 T7420 T7419 arg2Of those,than
R596 T787 T784 arg2Of damage,induce
R5960 T7420 T7421 arg1Of those,in
R5961 T7423 T7421 arg2Of astrocytes,in
R5962 T7423 T7422 arg1Of astrocytes,wildtype
R5963 T7423 T7424 arg1Of astrocytes,for
R5964 T7427 T7424 arg2Of time,for
R5965 T7427 T7425 arg1Of time,the
R5966 T7427 T7426 arg1Of time,first
R5967 T7428 T7429 arg1Of It,has
R5968 T7428 T7430 arg1Of It,been
R5969 T7428 T7431 arg2Of It,demonstrated
R597 T787 T786 arg1Of damage,aggravated
R5970 T7431 T7429 arg2Of demonstrated,has
R5971 T7431 T7430 arg2Of demonstrated,been
R5972 T7433 T7434 arg1Of NF-κB,is
R5973 T7433 T7435 arg2Of NF-κB,activated
R5974 T7435 T7431 arg3Of activated,demonstrated
R5975 T7435 T7432 arg1Of activated,that
R5976 T7435 T7434 arg2Of activated,is
R5977 T7435 T7436 arg1Of activated,in
R5978 T7435 T7441 arg1Of activated,after
R5979 T7435 T7444 arg1Of activated,[
R598 T787 T788 arg1Of damage,in
R5980 T7437 T7438 arg1Of brain,and
R5981 T7438 T7436 arg2Of and,in
R5982 T7440 T7438 arg2Of cord,and
R5983 T7440 T7439 arg1Of cord,spinal
R5984 T7443 T7441 arg2Of injury,after
R5985 T7443 T7442 arg1Of injury,traumatic
R5986 T7445 T7444 arg2Of 2,[
R5987 T7445 T7446 arg1Of 2,","
R5988 T7447 T7446 arg2Of 9,","
R5989 T7448 T7444 arg3Of ],[
R599 T791 T788 arg2Of mice,in
R5990 T7452 T7449 arg2Of factor,As
R5991 T7452 T7450 arg1Of factor,a
R5992 T7452 T7451 arg1Of factor,transcript
R5993 T7454 T7455 arg1Of NF-κB,binds
R5994 T7454 T7463 arg1Of NF-κB,induces
R5995 T7455 T7456 arg1Of binds,with
R5996 T7455 T7458 arg1Of binds,once
R5997 T7455 T7462 arg1Of binds,and
R5998 T7457 T7456 arg2Of DNA,with
R5999 T7459 T7460 arg1Of it,was
R600 T791 T789 arg1Of mice,Nrf2
R6000 T7459 T7461 arg2Of it,activated
R6001 T7461 T7458 arg2Of activated,once
R6002 T7461 T7460 arg2Of activated,was
R6003 T7462 T7449 arg1Of and,As
R6004 T7462 T7453 arg1Of and,","
R6005 T7463 T7462 arg2Of induces,and
R6006 T7464 T7463 arg2Of transcription,induces
R6007 T7464 T7465 arg1Of transcription,of
R6008 T7464 T7470 arg1Of transcription,of
R6009 T7466 T7467 arg1Of MMP9,and
R601 T791 T790 arg1Of mice,knockout
R6010 T7467 T7465 arg2Of and,of
R6011 T7469 T7467 arg2Of battery,and
R6012 T7469 T7468 arg1Of battery,a
R6013 T7472 T7470 arg2Of cytokines,of
R6014 T7472 T7471 arg1Of cytokines,proinflammatory
R6015 T7472 T7473 arg1Of cytokines,","
R6016 T7472 T7474 arg1Of cytokines,including
R6017 T7475 T7476 arg1Of TNF-α,","
R6018 T7476 T7479 arg1Of ",",and
R6019 T7477 T7476 arg2Of IL-1β,","
R602 T793 T792 arg2Of in,than
R6020 T7479 T7474 arg2Of and,including
R6021 T7479 T7478 arg1Of and,","
R6022 T7479 T7481 arg1Of and,","
R6023 T7479 T7482 arg1Of and,in
R6024 T7479 T7485 arg1Of and,after
R6025 T7480 T7479 arg2Of IL-6,and
R6026 T7484 T7482 arg2Of tissues,in
R6027 T7484 T7483 arg1Of tissues,brain
R6028 T7486 T7485 arg2Of TBI,after
R6029 T7486 T7487 arg1Of TBI,[
R603 T795 T793 arg2Of mice,in
R6030 T7488 T7489 arg1Of 3,","
R6031 T7489 T7487 arg2Of ",",[
R6032 T7489 T7491 arg1Of ",",","
R6033 T7490 T7489 arg2Of 10,","
R6034 T7492 T7491 arg2Of 11,","
R6035 T7493 T7487 arg3Of ],[
R6036 T7495 T7494 arg1Of results,Our
R6037 T7495 T7497 arg1Of results,revealed
R6038 T7497 T7496 arg1Of revealed,also
R6039 T7500 T7499 arg1Of injury,scratch
R604 T795 T794 arg1Of mice,wildtype
R6040 T7500 T7501 arg1Of injury,induced
R6041 T7501 T7497 arg2Of induced,revealed
R6042 T7501 T7498 arg1Of induced,that
R6043 T7502 T7501 arg2Of elevation,induced
R6044 T7502 T7503 arg1Of elevation,of
R6045 T7507 T7504 arg1Of activity,NF-κB
R6046 T7507 T7505 arg1Of activity,DNA
R6047 T7507 T7506 arg1Of activity,binding
R6048 T7507 T7508 arg1Of activity,","
R6049 T7508 T7513 arg1Of ",",and
R605 T797 T796 arg2Of 5,[
R6050 T7509 T7508 arg2Of overexpression,","
R6051 T7509 T7510 arg1Of overexpression,of
R6052 T7511 T7510 arg2Of MMP9,of
R6053 T7513 T7503 arg2Of and,of
R6054 T7513 T7512 arg1Of and,","
R6055 T7515 T7513 arg2Of mediators,and
R6056 T7515 T7514 arg1Of mediators,proinflammatory
R6057 T7515 T7516 arg2Of mediators,mentioned
R6058 T7516 T7517 arg1Of mentioned,above
R6059 T7516 T7518 arg1Of mentioned,in
R606 T798 T796 arg3Of ],[
R6060 T7520 T7518 arg2Of astrocytes,in
R6061 T7520 T7519 arg2Of astrocytes,cultured
R6062 T7521 T7522 arg1Of It,has
R6063 T7521 T7523 arg1Of It,been
R6064 T7521 T7524 arg2Of It,demonstrated
R6065 T7524 T7522 arg2Of demonstrated,has
R6066 T7524 T7523 arg2Of demonstrated,been
R6067 T7526 T7527 arg1Of there,is
R6068 T7527 T7524 arg3Of is,demonstrated
R6069 T7527 T7525 arg1Of is,that
R607 T801 T799 arg2Of contrary,On
R6070 T7530 T7527 arg2Of loop,is
R6071 T7530 T7528 arg1Of loop,an
R6072 T7530 T7529 arg1Of loop,autoregulatory
R6073 T7530 T7531 arg1Of loop,among
R6074 T7534 T7531 arg2Of mediators,among
R6075 T7534 T7532 arg1Of mediators,these
R6076 T7534 T7533 arg1Of mediators,proinflammatory
R6077 T7536 T7535 arg2Of example,For
R6078 T7538 T7539 arg1Of TNF-α,and
R6079 T7539 T7541 arg1Of and,are
R608 T801 T800 arg1Of contrary,the
R6080 T7540 T7539 arg2Of IL-1β,and
R6081 T7541 T7554 arg1Of are,and
R6082 T7543 T7541 arg2Of stimulators,are
R6083 T7543 T7542 arg1Of stimulators,potent
R6084 T7543 T7544 arg1Of stimulators,for
R6085 T7543 T7546 arg1Of stimulators,in
R6086 T7545 T7544 arg2Of MMP9,for
R6087 T7547 T7546 arg2Of astrocytes,in
R6088 T7547 T7548 arg1Of astrocytes,[
R6089 T7549 T7550 arg1Of 12,","
R609 T804 T803 arg1Of inflammation,such
R6090 T7550 T7548 arg2Of ",",[
R6091 T7551 T7550 arg2Of 13,","
R6092 T7552 T7548 arg3Of ],[
R6093 T7554 T7535 arg1Of and,For
R6094 T7554 T7537 arg1Of and,","
R6095 T7554 T7553 arg1Of and,","
R6096 T7555 T7556 arg1Of IL-6,induces
R6097 T7556 T7560 arg1Of induces,in
R6098 T7556 T7569 arg1Of induces,and
R6099 T7557 T7556 arg2Of overexpression,induces
R610 T804 T805 arg1Of inflammation,can
R6100 T7557 T7558 arg1Of overexpression,of
R6101 T7559 T7558 arg2Of MMP9,of
R6102 T7564 T7560 arg2Of cells,in
R6103 T7564 T7561 arg1Of cells,human
R6104 T7564 T7562 arg1Of cells,colon
R6105 T7564 T7563 arg1Of cells,carcinoma
R6106 T7564 T7565 arg1Of cells,[
R6107 T7566 T7565 arg2Of 14,[
R6108 T7567 T7565 arg3Of ],[
R6109 T7569 T7554 arg2Of and,and
R611 T804 T806 arg1Of inflammation,be
R6110 T7569 T7568 arg1Of and,","
R6111 T7570 T7571 arg1Of TNF-α,and
R6112 T7571 T7574 arg1Of and,can
R6113 T7571 T7575 arg1Of and,induce
R6114 T7572 T7571 arg2Of IL-1β,and
R6115 T7575 T7569 arg2Of induce,and
R6116 T7575 T7573 arg1Of induce,also
R6117 T7575 T7574 arg2Of induce,can
R6118 T7575 T7579 arg1Of induce,[
R6119 T7576 T7575 arg2Of activation,induce
R612 T804 T807 arg2Of inflammation,extenuated
R6120 T7576 T7577 arg1Of activation,of
R6121 T7578 T7577 arg2Of NF-κB,of
R6122 T7580 T7579 arg2Of 15,[
R6123 T7580 T7581 arg1Of 15,","
R6124 T7582 T7581 arg2Of 16,","
R6125 T7583 T7579 arg3Of ],[
R6126 T7586 T7584 arg1Of loop,This
R6127 T7586 T7585 arg1Of loop,autoregulatory
R6128 T7586 T7588 arg1Of loop,aggravates
R6129 T7586 T7595 arg1Of loop,induces
R613 T807 T799 arg1Of extenuated,On
R6130 T7588 T7594 arg1Of aggravates,and
R6131 T7591 T7588 arg2Of effect,aggravates
R6132 T7591 T7589 arg1Of effect,the
R6133 T7591 T7590 arg1Of effect,damaging
R6134 T7591 T7592 arg1Of effect,of
R6135 T7593 T7592 arg2Of inflammation,of
R6136 T7594 T7587 arg1Of and,extremely
R6137 T7595 T7594 arg2Of induces,and
R6138 T7597 T7595 arg2Of injury,induces
R6139 T7597 T7596 arg1Of injury,secondary
R614 T807 T802 arg1Of extenuated,","
R6140 T7597 T7598 arg1Of injury,to
R6141 T7599 T7598 arg2Of brain,to
R6142 T7600 T7601 arg1Of It,is
R6143 T7604 T7601 arg2Of choice,is
R6144 T7604 T7602 arg1Of choice,a
R6145 T7604 T7603 arg1Of choice,good
R6146 T7604 T7605 arg1Of choice,for
R6147 T7606 T7605 arg2Of targeting,for
R6148 T7606 T7607 arg1Of targeting,on
R6149 T7606 T7611 modOf targeting,to
R615 T807 T805 arg2Of extenuated,can
R6150 T7610 T7606 arg2Of factor,targeting
R6151 T7610 T7608 arg1Of factor,an
R6152 T7610 T7609 arg1Of factor,upstream
R6153 T7612 T7611 arg1Of prevent,to
R6154 T7612 T7616 arg1Of prevent,after
R6155 T7615 T7612 arg2Of loop,prevent
R6156 T7615 T7613 arg1Of loop,such
R6157 T7615 T7614 arg1Of loop,autoregulatory
R6158 T7617 T7616 arg2Of TBI,after
R6159 T7619 T7618 arg1Of pathway,Nrf2-ARE
R616 T807 T806 arg2Of extenuated,be
R6160 T7619 T7620 arg1Of pathway,has
R6161 T7619 T7621 arg1Of pathway,been
R6162 T7619 T7622 arg2Of pathway,proved
R6163 T7619 T7624 arg1Of pathway,be
R6164 T7622 T7620 arg2Of proved,has
R6165 T7622 T7621 arg2Of proved,been
R6166 T7624 T7622 arg3Of be,proved
R6167 T7624 T7623 arg1Of be,to
R6168 T7627 T7624 arg2Of regulator,be
R6169 T7627 T7625 arg1Of regulator,the
R617 T807 T808 arg1Of extenuated,through
R6170 T7627 T7626 arg1Of regulator,key
R6171 T7627 T7628 arg1Of regulator,in
R6172 T7629 T7628 arg2Of reducing,in
R6173 T7631 T7630 arg1Of stress,oxidative
R6174 T7631 T7632 arg1Of stress,","
R6175 T7632 T7636 arg1Of ",",and
R6176 T7634 T7632 arg2Of damage,","
R6177 T7634 T7633 arg1Of damage,inflammatory
R6178 T7636 T7629 arg2Of and,reducing
R6179 T7636 T7635 arg1Of and,","
R618 T809 T808 arg2Of elevating,through
R6180 T7637 T7636 arg2Of accumulation,and
R6181 T7637 T7638 arg1Of accumulation,of
R6182 T7640 T7638 arg2Of metabolites,of
R6183 T7640 T7639 arg1Of metabolites,toxic
R6184 T7640 T7641 arg1Of metabolites,","
R6185 T7640 T7642 arg1Of metabolites,which
R6186 T7640 T7643 arg1Of metabolites,are
R6187 T7640 T7645 arg2Of metabolites,involved
R6188 T7645 T7643 arg2Of involved,are
R6189 T7645 T7644 arg1Of involved,all
R619 T811 T809 arg2Of level,elevating
R6190 T7645 T7646 arg1Of involved,in
R6191 T7647 T7646 arg2Of TBI,in
R6192 T7650 T7648 arg1Of study,Our
R6193 T7650 T7649 arg1Of study,previous
R6194 T7650 T7651 arg1Of study,has
R6195 T7650 T7652 arg1Of study,proved
R6196 T7652 T7651 arg2Of proved,has
R6197 T7652 T7660 arg1Of proved,after
R6198 T7654 T7652 arg2Of augmentation,proved
R6199 T7654 T7653 arg1Of augmentation,the
R620 T811 T810 arg1Of level,the
R6200 T7654 T7655 arg1Of augmentation,of
R6201 T7654 T7657 arg1Of augmentation,in
R6202 T7656 T7655 arg2Of Nrf2,of
R6203 T7659 T7657 arg2Of tissue,in
R6204 T7659 T7658 arg1Of tissue,brain
R6205 T7661 T7660 arg2Of TBI,after
R6206 T7661 T7662 arg1Of TBI,[
R6207 T7663 T7662 arg2Of 17,[
R6208 T7664 T7662 arg3Of ],[
R6209 T7666 T7665 arg2Of level,Enhanced
R621 T811 T812 arg1Of level,of
R6210 T7666 T7667 arg1Of level,of
R6211 T7666 T7669 arg1Of level,activates
R6212 T7668 T7667 arg2Of Nrf2,of
R6213 T7670 T7669 arg2Of transcription,activates
R6214 T7670 T7671 arg1Of transcription,of
R6215 T7670 T7677 arg1Of transcription,","
R6216 T7670 T7679 arg1Of transcription,as
R6217 T7673 T7671 arg2Of group,of
R6218 T7673 T7672 arg1Of group,a
R6219 T7673 T7674 arg1Of group,of
R622 T811 T814 arg1Of level,by
R6220 T7676 T7674 arg2Of genes,of
R6221 T7676 T7675 arg1Of genes,antioxidant
R6222 T7679 T7678 arg1Of as,such
R6223 T7681 T7680 arg1Of oxygenase-1,heme
R6224 T7681 T7682 arg1Of oxygenase-1,(
R6225 T7681 T7685 arg1Of oxygenase-1,and
R6226 T7683 T7682 arg2Of HO-1,(
R6227 T7684 T7682 arg3Of ),(
R6228 T7685 T7679 arg2Of and,as
R6229 T7685 T7691 arg1Of and,:
R623 T811 T817 arg1Of level,","
R6230 T7688 T7687 arg2Of P,(
R6231 T7689 T7687 arg3Of ),(
R6232 T7690 T7685 arg2Of H,and
R6233 T7690 T7686 arg1Of H,NAD
R6234 T7690 T7687 arg1Of H,(
R6235 T7693 T7691 arg2Of oxidoreductase-1,:
R6236 T7693 T7692 arg1Of oxidoreductase-1,quinone
R6237 T7693 T7694 arg1Of oxidoreductase-1,(
R6238 T7693 T7697 arg1Of oxidoreductase-1,","
R6239 T7693 T7698 arg1Of oxidoreductase-1,which
R624 T811 T819 arg1Of level,as
R6240 T7693 T7699 arg1Of oxidoreductase-1,would
R6241 T7693 T7701 arg1Of oxidoreductase-1,reduce
R6242 T7695 T7694 arg2Of NQO1,(
R6243 T7696 T7694 arg3Of ),(
R6244 T7701 T7699 arg2Of reduce,would
R6245 T7701 T7700 arg1Of reduce,subsequently
R6246 T7703 T7701 arg2Of damage,reduce
R6247 T7703 T7702 arg1Of damage,the
R6248 T7703 T7704 arg1Of damage,in
R6249 T7705 T7704 arg2Of brain,in
R625 T813 T812 arg2Of Nrf2,of
R6250 T7705 T7706 arg1Of brain,[
R6251 T7707 T7706 arg2Of 18,[
R6252 T7708 T7706 arg3Of ],[
R6253 T7710 T7709 arg1Of administration,Postinjury
R6254 T7710 T7711 arg1Of administration,of
R6255 T7710 T7720 arg1Of administration,improves
R6256 T7710 T7726 arg1Of administration,decreases
R6257 T7712 T7711 arg2Of SFN,of
R6258 T7712 T7713 arg1Of SFN,","
R6259 T7715 T7713 arg2Of inducer,","
R626 T816 T814 arg2Of inducers,by
R6260 T7715 T7714 arg1Of inducer,an
R6261 T7715 T7716 arg1Of inducer,of
R6262 T7717 T7716 arg2Of Nrf2,of
R6263 T7720 T7725 arg1Of improves,and
R6264 T7722 T7720 arg2Of memory,improves
R6265 T7722 T7721 arg1Of memory,spatial
R6266 T7722 T7723 arg1Of memory,of
R6267 T7724 T7723 arg2Of rat,of
R6268 T7725 T7718 arg1Of and,","
R6269 T7725 T7719 arg1Of and,significantly
R627 T816 T815 arg1Of inducers,its
R6270 T7726 T7725 arg2Of decreases,and
R6271 T7728 T7726 arg2Of immunoreactivity,decreases
R6272 T7728 T7727 arg1Of immunoreactivity,the
R6273 T7728 T7729 arg1Of immunoreactivity,for
R6274 T7728 T7740 arg1Of immunoreactivity,","
R6275 T7728 T7741 arg1Of immunoreactivity,in
R6276 T7730 T7729 arg2Of 4-Hydroxynonenal,for
R6277 T7730 T7731 arg1Of 4-Hydroxynonenal,(
R6278 T7730 T7734 arg1Of 4-Hydroxynonenal,","
R6279 T7732 T7731 arg2Of 4-HNE,(
R628 T819 T818 arg1Of as,such
R6280 T7733 T7731 arg3Of ),(
R6281 T7736 T7734 arg2Of marker,","
R6282 T7736 T7735 arg1Of marker,a
R6283 T7736 T7737 arg1Of marker,of
R6284 T7739 T7737 arg2Of peroxidation,of
R6285 T7739 T7738 arg1Of peroxidation,lipid
R6286 T7743 T7742 arg1Of cortex,the
R6287 T7743 T7744 arg1Of cortex,and
R6288 T7744 T7741 arg2Of and,in
R6289 T7747 T7744 arg2Of subfield,and
R629 T820 T819 arg2Of sulforaphane,as
R6290 T7747 T7745 arg1Of subfield,the
R6291 T7747 T7746 arg1Of subfield,CA3
R6292 T7747 T7748 arg1Of subfield,of
R6293 T7747 T7750 arg1Of subfield,after
R6294 T7749 T7748 arg2Of hippocampus,of
R6295 T7751 T7750 arg2Of TBI,after
R6296 T7751 T7752 arg1Of TBI,[
R6297 T7753 T7752 arg2Of 19,[
R6298 T7754 T7752 arg3Of ],[
R6299 T7758 T7755 arg2Of hand,On
R630 T820 T821 arg1Of sulforaphane,(
R6300 T7758 T7756 arg1Of hand,the
R6301 T7758 T7757 arg1Of hand,other
R6302 T7761 T7760 arg1Of mice,Nrf2-deficient
R6303 T7761 T7762 arg1Of mice,appear
R6304 T7761 T7764 arg1Of mice,susceptible
R6305 T7762 T7755 arg1Of appear,On
R6306 T7762 T7759 arg1Of appear,","
R6307 T7764 T7762 arg2Of susceptible,appear
R6308 T7764 T7763 arg1Of susceptible,more
R6309 T7764 T7765 arg1Of susceptible,to
R631 T820 T824 arg1Of sulforaphane,[
R6310 T7766 T7765 arg2Of TBI,to
R6311 T7767 T7768 arg1Of Depletion,of
R6312 T7767 T7770 arg1Of Depletion,induces
R6313 T7769 T7768 arg2Of Nrf2,of
R6314 T7770 T7776 arg1Of induces,in
R6315 T7772 T7770 arg2Of expression,induces
R6316 T7772 T7771 arg1Of expression,higher
R6317 T7772 T7773 arg1Of expression,of
R6318 T7775 T7773 arg2Of mediators,of
R6319 T7775 T7774 arg1Of mediators,proinflammatory
R632 T822 T821 arg2Of SFN,(
R6320 T7777 T7776 arg2Of brain,in
R6321 T7777 T7778 arg1Of brain,after
R6322 T7779 T7778 arg2Of TBI,after
R6323 T7779 T7780 arg1Of TBI,[
R6324 T7781 T7780 arg2Of 20,[
R6325 T7782 T7780 arg3Of ],[
R6326 T7786 T7785 arg1Of results,our
R6327 T7786 T7787 arg1Of results,revealed
R6328 T7787 T7783 arg1Of revealed,Here
R6329 T7787 T7784 arg1Of revealed,","
R633 T823 T821 arg3Of ),(
R6330 T7789 T7790 arg1Of overexpression,of
R6331 T7789 T7802 arg1Of overexpression,was
R6332 T7789 T7804 arg2Of overexpression,aggravated
R6333 T7791 T7792 arg1Of TNF-α,","
R6334 T7792 T7794 arg1Of ",",","
R6335 T7793 T7792 arg2Of IL-1β,","
R6336 T7794 T7797 arg1Of ",",and
R6337 T7795 T7794 arg2Of IL-6,","
R6338 T7797 T7790 arg2Of and,of
R6339 T7797 T7796 arg1Of and,","
R634 T825 T824 arg2Of 6,[
R6340 T7797 T7799 arg1Of and,after
R6341 T7798 T7797 arg2Of MMP9,and
R6342 T7801 T7799 arg2Of injury,after
R6343 T7801 T7800 arg1Of injury,scratch
R6344 T7804 T7802 arg2Of aggravated,was
R6345 T7804 T7803 arg1Of aggravated,more
R6346 T7804 T7805 arg1Of aggravated,in
R6347 T7804 T7810 arg1Of aggravated,than
R6348 T7804 T7814 arg1Of aggravated,for
R6349 T7804 T7819 arg1Of aggravated,and
R635 T826 T824 arg3Of ],[
R6350 T7809 T7805 arg2Of astrocytes,in
R6351 T7809 T7806 arg2Of astrocytes,cultured
R6352 T7809 T7807 arg1Of astrocytes,Nrf2
R6353 T7809 T7808 arg1Of astrocytes,knockout
R6354 T7811 T7810 arg2Of in,than
R6355 T7813 T7811 arg2Of astrocyetes,in
R6356 T7813 T7812 arg1Of astrocyetes,wildtype
R6357 T7817 T7814 arg2Of time,for
R6358 T7817 T7815 arg1Of time,the
R6359 T7817 T7816 arg1Of time,first
R636 T827 T828 arg1Of It,is
R6360 T7819 T7787 arg2Of and,revealed
R6361 T7819 T7788 arg1Of and,that
R6362 T7819 T7818 arg1Of and,","
R6363 T7820 T7821 arg1Of overexpression,of
R6364 T7820 T7825 arg1Of overexpression,led
R6365 T7824 T7821 arg2Of mediators,of
R6366 T7824 T7822 arg1Of mediators,these
R6367 T7824 T7823 arg1Of mediators,proinflammatory
R6368 T7825 T7819 arg2Of led,and
R6369 T7825 T7826 arg1Of led,to
R637 T827 T830 arg2Of It,documented
R6370 T7829 T7826 arg2Of deaths,to
R6371 T7829 T7827 arg1Of deaths,more
R6372 T7829 T7828 arg1Of deaths,astrocytes
R6373 T7830 T7831 arg2Of Data,obtained
R6374 T7830 T7835 arg1Of Data,suggest
R6375 T7831 T7832 arg1Of obtained,from
R6376 T7834 T7832 arg2Of studies,from
R6377 T7834 T7833 arg1Of studies,animal
R6378 T7837 T7835 arg2Of possibility,suggest
R6379 T7837 T7836 arg1Of possibility,the
R638 T830 T828 arg2Of documented,is
R6380 T7840 T7839 arg1Of effect,antioxidant
R6381 T7840 T7841 arg1Of effect,of
R6382 T7840 T7843 arg1Of effect,may
R6383 T7840 T7844 arg1Of effect,be
R6384 T7840 T7845 arg2Of effect,achieved
R6385 T7842 T7841 arg2Of Nrf2,of
R6386 T7845 T7837 arg2Of achieved,possibility
R6387 T7845 T7838 arg1Of achieved,that
R6388 T7845 T7843 arg2Of achieved,may
R6389 T7845 T7844 arg2Of achieved,be
R639 T830 T829 arg1Of documented,well
R6390 T7847 T7845 arg1Of suppression,achieved
R6391 T7847 T7846 arg2Of suppression,by
R6392 T7847 T7848 arg1Of suppression,of
R6393 T7850 T7848 arg2Of pathways,of
R6394 T7850 T7849 arg1Of pathways,proinflammatory
R6395 T7850 T7851 arg1Of pathways,which
R6396 T7850 T7852 arg1Of pathways,are
R6397 T7850 T7853 arg2Of pathways,mediated
R6398 T7853 T7852 arg2Of mediated,are
R6399 T7856 T7853 arg1Of signaling,mediated
R640 T832 T833 arg1Of astrocytes,play
R6400 T7856 T7854 arg2Of signaling,by
R6401 T7856 T7855 arg1Of signaling,NF-κB
R6402 T7857 T7858 arg1Of Administration,of
R6403 T7857 T7860 arg1Of Administration,is
R6404 T7857 T7861 arg2Of Administration,found
R6405 T7857 T7863 arg1Of Administration,be
R6406 T7857 T7864 arg1Of Administration,able
R6407 T7857 T7866 arg1Of Administration,inhibit
R6408 T7857 T7877 arg1Of Administration,alleviating
R6409 T7859 T7858 arg2Of SFN,of
R641 T833 T830 arg3Of play,documented
R6410 T7861 T7860 arg2Of found,is
R6411 T7863 T7861 arg3Of be,found
R6412 T7863 T7862 arg1Of be,to
R6413 T7864 T7863 arg2Of able,be
R6414 T7866 T7864 arg2Of inhibit,able
R6415 T7866 T7865 arg1Of inhibit,to
R6416 T7866 T7875 arg1Of inhibit,","
R6417 T7866 T7877 modOf inhibit,alleviating
R6418 T7868 T7867 arg1Of phosphorylation,IKK/IκB
R6419 T7868 T7869 arg1Of phosphorylation,and
R642 T833 T831 arg1Of play,that
R6420 T7869 T7866 arg2Of and,inhibit
R6421 T7874 T7869 arg2Of translocation,and
R6422 T7874 T7870 arg1Of translocation,p65
R6423 T7874 T7871 arg1Of translocation,NF-κB
R6424 T7874 T7872 arg1Of translocation,subunit
R6425 T7874 T7873 arg1Of translocation,nuclear
R6426 T7877 T7876 arg1Of alleviating,consequently
R6427 T7879 T7877 arg2Of signaling,alleviating
R6428 T7879 T7878 arg1Of signaling,NF-κB
R6429 T7879 T7880 arg1Of signaling,[
R643 T833 T837 arg1Of play,in
R6430 T7881 T7880 arg2Of 21,[
R6431 T7882 T7880 arg3Of ],[
R6432 T7885 T7884 arg1Of activation,NF-κB
R6433 T7885 T7886 arg2Of activation,induced
R6434 T7885 T7892 arg1Of activation,could
R6435 T7885 T7893 arg1Of activation,be
R6436 T7885 T7894 arg2Of activation,attenuated
R6437 T7888 T7886 arg1Of lipopolysaccharide,induced
R6438 T7888 T7887 arg2Of lipopolysaccharide,by
R6439 T7888 T7889 arg1Of lipopolysaccharide,(
R644 T836 T833 arg2Of role,play
R6440 T7890 T7889 arg2Of LPS,(
R6441 T7891 T7889 arg3Of ),(
R6442 T7894 T7883 arg1Of attenuated,And
R6443 T7894 T7892 arg2Of attenuated,could
R6444 T7894 T7893 arg2Of attenuated,be
R6445 T7894 T7908 arg1Of attenuated,[
R6446 T7898 T7894 arg1Of activators,attenuated
R6447 T7898 T7895 arg2Of activators,by
R6448 T7898 T7896 arg1Of activators,diverse
R6449 T7898 T7897 arg1Of activators,Nrf2
R645 T836 T834 arg1Of role,a
R6450 T7898 T7899 arg1Of activators,","
R6451 T7898 T7901 arg1Of activators,as
R6452 T7901 T7900 arg1Of as,such
R6453 T7902 T7903 arg1Of SFN,and
R6454 T7903 T7901 arg2Of and,as
R6455 T7903 T7905 arg1Of and,(
R6456 T7904 T7903 arg2Of curcumin,and
R6457 T7906 T7905 arg2Of CUR,(
R6458 T7907 T7905 arg3Of ),(
R6459 T7909 T7908 arg2Of 22,[
R646 T836 T835 arg1Of role,critical
R6460 T7910 T7908 arg3Of ],[
R6461 T7915 T7913 arg1Of studies,our
R6462 T7915 T7914 arg1Of studies,previous
R6463 T7915 T7916 arg1Of studies,indicate
R6464 T7916 T7911 arg1Of indicate,Furthermore
R6465 T7916 T7912 arg1Of indicate,","
R6466 T7918 T7919 arg1Of depletion,of
R6467 T7918 T7921 arg1Of depletion,induces
R6468 T7920 T7919 arg2Of Nrf2,of
R6469 T7921 T7916 arg2Of induces,indicate
R647 T838 T842 arg1Of maintaining,and
R6470 T7921 T7917 arg1Of induces,that
R6471 T7922 T7921 arg2Of augmentation,induces
R6472 T7922 T7923 arg1Of augmentation,of
R6473 T7922 T7929 arg1Of augmentation,in
R6474 T7922 T7936 arg1Of augmentation,after
R6475 T7925 T7924 arg1Of activity,NF-κB
R6476 T7925 T7926 arg1Of activity,and
R6477 T7926 T7923 arg2Of and,of
R6478 T7928 T7926 arg2Of response,and
R6479 T7928 T7927 arg1Of response,inflammatory
R648 T841 T838 arg2Of physiology,maintaining
R6480 T7930 T7931 arg1Of lung,","
R6481 T7931 T7934 arg1Of ",",and
R6482 T7932 T7931 arg2Of brain,","
R6483 T7934 T7929 arg2Of and,in
R6484 T7934 T7933 arg1Of and,","
R6485 T7935 T7934 arg2Of intestine,and
R6486 T7937 T7936 arg2Of TBI,after
R6487 T7937 T7938 arg1Of TBI,[
R6488 T7939 T7940 arg1Of 4,","
R6489 T7940 T7938 arg2Of ",",[
R649 T841 T839 arg1Of physiology,normal
R6490 T7940 T7942 arg1Of ",",","
R6491 T7941 T7940 arg2Of 5,","
R6492 T7943 T7942 arg2Of 23,","
R6493 T7944 T7938 arg3Of ],[
R6494 T7945 T7946 arg1Of Results,from
R6495 T7945 T7950 arg1Of Results,confirmed
R6496 T7948 T7946 arg2Of study,from
R6497 T7948 T7947 arg1Of study,this
R6498 T7950 T7949 arg1Of confirmed,further
R6499 T7952 T7951 arg1Of relationship,such
R650 T841 T840 arg1Of physiology,brain
R6500 T7952 T7953 arg1Of relationship,existed
R6501 T7953 T7950 arg2Of existed,confirmed
R6502 T7953 T7954 arg1Of existed,in
R6503 T7953 T7957 arg1Of existed,after
R6504 T7956 T7954 arg2Of astrocytes,in
R6505 T7956 T7955 arg2Of astrocytes,cultured
R6506 T7959 T7957 arg2Of injury,after
R6507 T7959 T7958 arg1Of injury,scratch
R6508 T7961 T7960 arg2Of activation,Enhanced
R6509 T7961 T7962 arg1Of activation,of
R651 T842 T837 arg2Of and,in
R6510 T7961 T7964 arg1Of activation,is
R6511 T7961 T7966 arg2Of activation,discovered
R6512 T7963 T7962 arg2Of NF-κB,of
R6513 T7966 T7964 arg2Of discovered,is
R6514 T7966 T7965 arg1Of discovered,also
R6515 T7966 T7967 arg1Of discovered,in
R6516 T7966 T7979 arg1Of discovered,after
R6517 T7966 T7982 arg1Of discovered,[
R6518 T7968 T7969 arg1Of lung,","
R6519 T7969 T7972 arg1Of ",",and
R652 T843 T842 arg2Of responding,and
R6520 T7970 T7969 arg2Of macrophages,","
R6521 T7972 T7967 arg2Of and,in
R6522 T7972 T7971 arg1Of and,","
R6523 T7975 T7972 arg2Of fibroblasts,and
R6524 T7975 T7973 arg1Of fibroblasts,mouse
R6525 T7975 T7974 arg1Of fibroblasts,embryonic
R6526 T7975 T7976 arg1Of fibroblasts,of
R6527 T7978 T7976 arg2Of mice,of
R6528 T7978 T7977 arg1Of mice,Nrf2-deficient
R6529 T7981 T7979 arg2Of sepsis,after
R653 T843 T844 arg1Of responding,to
R6530 T7981 T7980 arg1Of sepsis,experimental
R6531 T7983 T7982 arg2Of 24,[
R6532 T7984 T7982 arg3Of ],[
R6533 T7987 T7988 arg1Of it,is
R6534 T7987 T7989 arg2Of it,reported
R6535 T7989 T7985 arg1Of reported,Interestingly
R6536 T7989 T7986 arg1Of reported,","
R6537 T7989 T7988 arg2Of reported,is
R6538 T7991 T7992 arg1Of NF-κB,can
R6539 T7991 T7993 arg1Of NF-κB,inhibit
R654 T845 T846 arg1Of injury,or
R6540 T7993 T7989 arg3Of inhibit,reported
R6541 T7993 T7990 arg1Of inhibit,that
R6542 T7993 T7992 arg2Of inhibit,can
R6543 T7993 T7995 arg1Of inhibit,at
R6544 T7994 T7993 arg2Of Nrf2,inhibit
R6545 T7997 T7995 arg2Of level,at
R6546 T7997 T7996 arg1Of level,transcriptional
R6547 T8000 T7998 arg1Of subunit,NF-κB
R6548 T8000 T7999 arg1Of subunit,p65
R6549 T8000 T8001 arg1Of subunit,repressed
R655 T846 T844 arg2Of or,to
R6550 T8001 T8008 arg1Of repressed,by
R6551 T8004 T8001 arg2Of pathway,repressed
R6552 T8004 T8002 arg1Of pathway,the
R6553 T8004 T8003 arg1Of pathway,Nrf2-ARE
R6554 T8004 T8005 arg1Of pathway,at
R6555 T8007 T8005 arg2Of level,at
R6556 T8007 T8006 arg1Of level,transcriptional
R6557 T8010 T8009 arg1Of interaction,competitive
R6558 T8010 T8011 arg1Of interaction,with
R6559 T8010 T8017 arg1Of interaction,or
R656 T847 T846 arg2Of disease,or
R6560 T8014 T8011 arg2Of domain,with
R6561 T8014 T8012 arg1Of domain,the
R6562 T8014 T8013 arg1Of domain,CH1-KIX
R6563 T8014 T8015 arg1Of domain,of
R6564 T8016 T8015 arg2Of CBP,of
R6565 T8017 T8008 arg2Of or,by
R6566 T8020 T8017 arg2Of hypoacetylation,or
R6567 T8020 T8018 arg1Of hypoacetylation,local
R6568 T8020 T8019 arg1Of hypoacetylation,histone
R6569 T8020 T8021 arg1Of hypoacetylation,[
R657 T849 T848 arg2Of fact,In
R6570 T8022 T8021 arg2Of 25,[
R6571 T8023 T8021 arg3Of ],[
R6572 T8026 T8024 arg1Of findings,All
R6573 T8026 T8025 arg1Of findings,these
R6574 T8026 T8027 arg1Of findings,indicate
R6575 T8031 T8027 arg2Of crosstalk,indicate
R6576 T8031 T8028 arg1Of crosstalk,the
R6577 T8031 T8029 arg1Of crosstalk,potential
R6578 T8031 T8030 arg1Of crosstalk,complicate
R6579 T8031 T8032 arg1Of crosstalk,between
R658 T854 T851 arg1Of studies,all
R6580 T8033 T8034 arg1Of NF-κB,and
R6581 T8034 T8032 arg2Of and,between
R6582 T8034 T8036 arg1Of and,","
R6583 T8034 T8037 arg1Of and,which
R6584 T8034 T8038 arg1Of and,may
R6585 T8034 T8039 arg1Of and,be
R6586 T8034 T8040 arg2Of and,regulated
R6587 T8035 T8034 arg2Of Nrf2,and
R6588 T8040 T8038 arg2Of regulated,may
R6589 T8040 T8039 arg2Of regulated,be
R659 T854 T852 arg1Of studies,the
R6590 T8040 T8051 arg1Of regulated,[
R6591 T8046 T8044 arg1Of kinase,mitogen-activated
R6592 T8046 T8045 arg1Of kinase,protein
R6593 T8046 T8047 arg1Of kinase,(
R6594 T8048 T8047 arg2Of MAPKs,(
R6595 T8049 T8047 arg3Of ),(
R6596 T8050 T8040 arg1Of pathway,regulated
R6597 T8050 T8041 arg2Of pathway,by
R6598 T8050 T8042 arg1Of pathway,the
R6599 T8050 T8043 arg1Of pathway,upstream
R660 T854 T853 arg1Of studies,aforementioned
R6600 T8050 T8046 arg1Of pathway,kinase
R6601 T8052 T8051 arg2Of 26,[
R6602 T8053 T8051 arg3Of ],[
R6603 T8057 T8055 arg2Of confirmed,has
R6604 T8057 T8056 arg2Of confirmed,been
R6605 T8059 T8060 arg1Of Nrf2,is
R6606 T8059 T8062 arg2Of Nrf2,detected
R6607 T8062 T8054 arg1Of detected,It
R6608 T8062 T8055 arg1Of detected,has
R6609 T8062 T8056 arg1Of detected,been
R661 T854 T855 arg1Of studies,are
R6610 T8062 T8057 arg2Of detected,confirmed
R6611 T8062 T8058 arg1Of detected,that
R6612 T8062 T8060 arg2Of detected,is
R6613 T8062 T8061 arg1Of detected,mainly
R6614 T8062 T8063 arg1Of detected,in
R6615 T8064 T8063 arg2Of nucleus,in
R6616 T8064 T8065 arg1Of nucleus,of
R6617 T8066 T8065 arg2Of astrocytes,of
R6618 T8066 T8067 arg1Of astrocytes,after
R6619 T8068 T8067 arg2Of TBI,after
R662 T854 T856 arg2Of studies,performed
R6620 T8068 T8069 arg1Of TBI,[
R6621 T8070 T8069 arg2Of 18,[
R6622 T8071 T8069 arg3Of ],[
R6623 T8073 T8072 arg2Of view,In
R6624 T8073 T8074 arg1Of view,of
R6625 T8076 T8074 arg2Of fact,of
R6626 T8076 T8075 arg1Of fact,the
R6627 T8078 T8079 arg1Of Nrf2,is
R6628 T8079 T8076 arg2Of is,fact
R6629 T8079 T8077 arg1Of is,that
R663 T856 T848 arg1Of performed,In
R6630 T8082 T8079 arg2Of factor,is
R6631 T8082 T8080 arg1Of factor,a
R6632 T8082 T8081 arg1Of factor,transcription
R6633 T8082 T8083 arg1Of factor,which
R6634 T8082 T8084 arg1Of factor,should
R6635 T8082 T8085 arg1Of factor,take
R6636 T8085 T8084 arg2Of take,should
R6637 T8085 T8088 arg1Of take,in
R6638 T8086 T8085 arg2Of function,take
R6639 T8088 T8087 arg1Of in,mainly
R664 T856 T850 arg1Of performed,","
R6640 T8089 T8088 arg2Of nucleus,in
R6641 T8091 T8092 arg1Of it,can
R6642 T8091 T8093 arg1Of it,be
R6643 T8091 T8094 arg2Of it,reasoned
R6644 T8094 T8072 arg1Of reasoned,In
R6645 T8094 T8090 arg1Of reasoned,","
R6646 T8094 T8092 arg2Of reasoned,can
R6647 T8094 T8093 arg2Of reasoned,be
R6648 T8096 T8097 arg1Of astrocytes,may
R6649 T8096 T8098 arg1Of astrocytes,be
R665 T856 T855 arg2Of performed,are
R6650 T8098 T8094 arg3Of be,reasoned
R6651 T8098 T8095 arg1Of be,that
R6652 T8098 T8097 arg2Of be,may
R6653 T8098 T8104 arg1Of be,in
R6654 T8100 T8098 arg2Of kind,be
R6655 T8100 T8099 arg1Of kind,one
R6656 T8100 T8101 arg1Of kind,of
R6657 T8103 T8101 arg2Of cells,of
R6658 T8103 T8102 arg1Of cells,respondent
R6659 T8105 T8104 arg2Of activation,in
R666 T856 T858 arg1Of performed,vivo
R6660 T8105 T8106 arg1Of activation,of
R6661 T8108 T8106 arg2Of pathway,of
R6662 T8108 T8107 arg1Of pathway,Nrf2-ARE
R6663 T8108 T8109 arg1Of pathway,after
R6664 T8110 T8109 arg2Of TBI,after
R6665 T8112 T8111 arg1Of study,Previous
R6666 T8112 T8113 arg1Of study,identified
R6667 T8113 T8126 arg1Of identified,after
R6668 T8115 T8113 arg2Of expression,identified
R6669 T8115 T8114 arg1Of expression,the
R667 T858 T857 arg1Of vivo,in
R6670 T8115 T8116 arg1Of expression,of
R6671 T8115 T8123 arg1Of expression,in
R6672 T8117 T8118 arg1Of TNF-α,","
R6673 T8118 T8121 arg1Of ",",and
R6674 T8119 T8118 arg2Of IL-1β,","
R6675 T8121 T8116 arg2Of and,of
R6676 T8121 T8120 arg1Of and,","
R6677 T8122 T8121 arg2Of IL-6,and
R6678 T8125 T8123 arg2Of astrocytes,in
R6679 T8125 T8124 arg2Of astrocytes,cultured
R668 T859 T860 arg1Of Little,is
R6680 T8127 T8126 arg2Of treatment,after
R6681 T8127 T8128 arg1Of treatment,with
R6682 T8129 T8130 arg1Of LPS,or
R6683 T8130 T8128 arg2Of or,with
R6684 T8130 T8132 arg1Of or,[
R6685 T8131 T8130 arg2Of oxyhemoglobin,or
R6686 T8133 T8132 arg2Of 27,[
R6687 T8133 T8134 arg1Of 27,","
R6688 T8135 T8134 arg2Of 28,","
R6689 T8136 T8132 arg3Of ],[
R669 T859 T861 arg2Of Little,known
R6690 T8138 T8137 arg1Of study,Another
R6691 T8138 T8139 arg1Of study,revealed
R6692 T8145 T8141 arg2Of occlusion,after
R6693 T8145 T8142 arg1Of occlusion,middle
R6694 T8145 T8143 arg1Of occlusion,cerebral
R6695 T8145 T8144 arg1Of occlusion,artery
R6696 T8148 T8147 arg1Of astrocytes,MMP9-positive
R6697 T8148 T8149 arg1Of astrocytes,were
R6698 T8148 T8150 arg2Of astrocytes,observed
R6699 T8150 T8139 arg2Of observed,revealed
R670 T861 T860 arg2Of known,is
R6700 T8150 T8140 arg1Of observed,that
R6701 T8150 T8141 arg1Of observed,after
R6702 T8150 T8146 arg1Of observed,","
R6703 T8150 T8149 arg2Of observed,were
R6704 T8150 T8151 arg1Of observed,in
R6705 T8150 T8154 arg1Of observed,by
R6706 T8150 T8156 arg1Of observed,[
R6707 T8153 T8151 arg2Of tissues,in
R6708 T8153 T8152 arg1Of tissues,brain
R6709 T8155 T8154 arg2Of immunohistochemistry,by
R671 T861 T862 arg1Of known,about
R6710 T8157 T8156 arg2Of 29,[
R6711 T8158 T8156 arg3Of ],[
R6712 T8160 T8159 arg1Of results,Those
R6713 T8160 T8161 arg1Of results,indicate
R6714 T8161 T8169 arg1Of indicate,after
R6715 T8163 T8161 arg2Of role,indicate
R6716 T8163 T8162 arg1Of role,the
R6717 T8163 T8164 arg1Of role,of
R6718 T8163 T8166 arg1Of role,in
R6719 T8165 T8164 arg2Of astrocytes,of
R672 T864 T862 arg2Of relationship,about
R6720 T8168 T8166 arg2Of process,in
R6721 T8168 T8167 arg1Of process,inflammatory
R6722 T8171 T8169 arg2Of injury,after
R6723 T8171 T8170 arg1Of injury,brain
R6724 T8174 T8177 modOf now,is
R6725 T8174 T8180 arg1Of now,focused
R6726 T8176 T8177 arg1Of there,is
R6727 T8177 T8175 arg1Of is,","
R6728 T8179 T8177 arg2Of study,is
R6729 T8179 T8178 arg1Of study,no
R673 T864 T863 arg1Of relationship,the
R6730 T8180 T8172 arg1Of focused,But
R6731 T8180 T8173 arg1Of focused,till
R6732 T8180 T8181 arg1Of focused,on
R6733 T8180 T8192 arg1Of focused,after
R6734 T8183 T8181 arg2Of relationship,on
R6735 T8183 T8182 arg1Of relationship,the
R6736 T8183 T8184 arg1Of relationship,among
R6737 T8185 T8186 arg1Of astrocytes,","
R6738 T8186 T8189 arg1Of ",",and
R6739 T8187 T8186 arg2Of Nrf2,","
R674 T864 T865 arg1Of relationship,between
R6740 T8189 T8184 arg2Of and,among
R6741 T8189 T8188 arg1Of and,","
R6742 T8191 T8189 arg2Of mediators,and
R6743 T8191 T8190 arg1Of mediators,proinflammatory
R6744 T8193 T8192 arg2Of TBI,after
R6745 T8195 T8194 arg1Of results,Our
R6746 T8195 T8196 arg1Of results,demonstrated
R6747 T8199 T8196 arg2Of expression,demonstrated
R6748 T8199 T8197 arg1Of expression,the
R6749 T8199 T8198 arg2Of expression,upregulated
R675 T866 T867 arg1Of Nrf2,and
R6750 T8199 T8200 arg1Of expression,of
R6751 T8199 T8209 arg1Of expression,in
R6752 T8201 T8202 arg1Of TNF-α,","
R6753 T8202 T8204 arg1Of ",",","
R6754 T8203 T8202 arg2Of IL-1β,","
R6755 T8204 T8207 arg1Of ",",and
R6756 T8205 T8204 arg2Of IL-6,","
R6757 T8207 T8200 arg2Of and,of
R6758 T8207 T8206 arg1Of and,","
R6759 T8208 T8207 arg2Of MMP9,and
R676 T867 T865 arg2Of and,between
R6760 T8212 T8209 arg2Of astrocytes,in
R6761 T8212 T8210 arg1Of astrocytes,Nrf2
R6762 T8212 T8211 arg1Of astrocytes,knockout
R6763 T8212 T8213 arg1Of astrocytes,after
R6764 T8215 T8213 arg2Of injury,after
R6765 T8215 T8214 arg1Of injury,scratch
R6766 T8215 T8216 arg1Of injury,for
R6767 T8219 T8216 arg2Of time,for
R6768 T8219 T8217 arg1Of time,the
R6769 T8219 T8218 arg1Of time,first
R677 T867 T869 arg1Of and,in
R6770 T8221 T8220 arg2Of conclusion,In
R6771 T8223 T8224 arg1Of depletion,of
R6772 T8223 T8226 arg1Of depletion,induced
R6773 T8225 T8224 arg2Of Nrf2,of
R6774 T8226 T8220 arg1Of induced,In
R6775 T8226 T8222 arg1Of induced,","
R6776 T8226 T8243 modOf induced,resulting
R6777 T8228 T8227 arg1Of activation,the
R6778 T8228 T8229 arg1Of activation,of
R6779 T8228 T8231 arg1Of activation,and
R678 T867 T871 arg1Of and,after
R6780 T8230 T8229 arg2Of NF-κB,of
R6781 T8231 T8226 arg2Of and,induced
R6782 T8233 T8231 arg2Of expression,and
R6783 T8233 T8232 arg1Of expression,the
R6784 T8233 T8234 arg1Of expression,of
R6785 T8235 T8236 arg1Of TNF-α,","
R6786 T8236 T8238 arg1Of ",",","
R6787 T8237 T8236 arg2Of IL-1β,","
R6788 T8238 T8241 arg1Of ",",and
R6789 T8239 T8238 arg2Of IL-6,","
R679 T868 T867 arg2Of inflammation,and
R6790 T8241 T8234 arg2Of and,of
R6791 T8241 T8240 arg1Of and,","
R6792 T8242 T8241 arg2Of MMP9,and
R6793 T8243 T8244 arg1Of resulting,in
R6794 T8247 T8244 arg2Of deaths,in
R6795 T8247 T8245 arg1Of deaths,more
R6796 T8247 T8246 arg1Of deaths,cell
R6797 T8247 T8248 arg1Of deaths,in
R6798 T8249 T8248 arg2Of astrocytes,in
R6799 T8249 T8250 arg1Of astrocytes,after
R680 T870 T869 arg2Of astrocytes,in
R6800 T8252 T8250 arg2Of injury,after
R6801 T8252 T8251 arg1Of injury,scratch
R6802 T8254 T8253 arg1Of results,These
R6803 T8254 T8255 arg1Of results,suggest
R6804 T8257 T8258 arg1Of Nrf2,may
R6805 T8257 T8259 arg1Of Nrf2,be
R6806 T8259 T8255 arg2Of be,suggest
R6807 T8259 T8256 arg1Of be,that
R6808 T8259 T8258 arg2Of be,may
R6809 T8262 T8259 arg2Of target,be
R681 T872 T871 arg2Of TBI,after
R6810 T8262 T8260 arg1Of target,an
R6811 T8262 T8261 arg1Of target,important
R6812 T8262 T8263 arg1Of target,for
R6813 T8262 T8266 arg1Of target,after
R6814 T8265 T8263 arg2Of therapy,for
R6815 T8265 T8264 arg1Of therapy,anti-inflammatory
R6816 T8267 T8266 arg2Of TBI,after
R682 T876 T877 arg1Of we,analysed
R683 T877 T873 arg1Of analysed,Therefore
R684 T877 T874 arg1Of analysed,","
R685 T877 T875 arg1Of analysed,here
R686 T879 T877 arg2Of influence,analysed
R687 T879 T878 arg1Of influence,the
R688 T879 T880 arg1Of influence,of
R689 T879 T882 arg1Of influence,on
R690 T881 T880 arg2Of Nrf2,of
R691 T884 T882 arg2Of expression,on
R692 T884 T883 arg1Of expression,the
R693 T884 T885 arg1Of expression,of
R694 T884 T888 arg1Of expression,in
R695 T887 T885 arg2Of cytokines,of
R696 T887 T886 arg1Of cytokines,proinflammatory
R697 T891 T888 arg2Of astrocytes,in
R698 T891 T889 arg1Of astrocytes,primary
R699 T891 T890 arg2Of astrocytes,cultured
R700 T891 T892 arg1Of astrocytes,from
R701 T894 T892 arg2Of mice,from
R702 T894 T893 arg1Of mice,transgenic
R703 T894 T895 arg1Of mice,after
R704 T897 T895 arg2Of injury,after
R705 T897 T896 arg1Of injury,scratch
R985 T1242 T1243 arg1Of Culture,and
R986 T1243 T1241 arg1Of and,Primary
R987 T1243 T1245 arg1Of and,of
R988 T1244 T1243 arg2Of Identification,and
R989 T1247 T1245 arg2Of Astrocytes,of
R990 T1247 T1246 arg1Of Astrocytes,Mouse
R991 T1251 T1248 arg1Of mice,Nrf2
R992 T1251 T1249 arg1Of mice,knockout
R993 T1251 T1250 arg1Of mice,ICR
R994 T1251 T1252 arg1Of mice,were
R995 T1251 T1254 arg2Of mice,provided
R996 T1254 T1252 arg2Of provided,were
R997 T1254 T1253 arg1Of provided,kindly
R998 T1259 T1254 arg1Of Kensler,provided
R999 T1259 T1255 arg2Of Kensler,by