| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1271 |
11-17 |
NN |
denotes |
Status |
| T1272 |
18-29 |
NN |
denotes |
epilepticus |
| T1273 |
30-31 |
-LRB- |
denotes |
( |
| T1274 |
31-33 |
NN |
denotes |
SE |
| T1275 |
33-34 |
-RRB- |
denotes |
) |
| T1276 |
35-37 |
VB |
denotes |
is |
| T1277 |
38-39 |
DT |
denotes |
a |
| T1278 |
40-47 |
JJ |
denotes |
medical |
| T1279 |
48-57 |
NN |
denotes |
emergency |
| T1280 |
58-62 |
IN |
denotes |
with |
| T1281 |
63-74 |
JJ |
denotes |
significant |
| T1282 |
75-84 |
NN |
denotes |
mortality |
| T1283 |
85-86 |
-LRB- |
denotes |
[ |
| T1284 |
86-87 |
CD |
denotes |
1 |
| T1285 |
87-88 |
-RRB- |
denotes |
] |
| T1286 |
90-92 |
NN |
denotes |
SE |
| T1287 |
93-96 |
VB |
denotes |
has |
| T1288 |
97-101 |
VB |
denotes |
been |
| T1289 |
102-109 |
VB |
denotes |
defined |
| T1290 |
110-112 |
IN |
denotes |
as |
| T1291 |
113-123 |
JJ |
denotes |
continuous |
| T1292 |
124-131 |
NN |
denotes |
seizure |
| T1293 |
132-140 |
NN |
denotes |
activity |
| T1294 |
140-141 |
-COMMA- |
denotes |
, |
| T1295 |
142-147 |
WDT |
denotes |
which |
| T1296 |
148-154 |
VB |
denotes |
causes |
| T1297 |
155-163 |
JJ |
denotes |
neuronal |
| T1298 |
164-168 |
NN |
denotes |
cell |
| T1299 |
169-174 |
NN |
denotes |
death |
| T1300 |
174-175 |
-COMMA- |
denotes |
, |
| T1301 |
176-191 |
NN |
denotes |
epileptogenesis |
| T1302 |
192-195 |
CC |
denotes |
and |
| T1303 |
196-204 |
VB |
denotes |
learning |
| T1304 |
205-215 |
NN |
denotes |
impairment |
| T1305 |
216-217 |
-LRB- |
denotes |
[ |
| T1306 |
217-220 |
CD |
denotes |
2,3 |
| T1307 |
220-221 |
-RRB- |
denotes |
] |
| T1308 |
223-227 |
DT |
denotes |
Some |
| T1309 |
228-233 |
NN |
denotes |
brain |
| T1310 |
234-241 |
NN |
denotes |
regions |
| T1311 |
242-252 |
JJ |
denotes |
vulnerable |
| T1312 |
253-255 |
TO |
denotes |
to |
| T1313 |
256-258 |
NN |
denotes |
SE |
| T1314 |
259-263 |
VB |
denotes |
play |
| T1315 |
264-265 |
DT |
denotes |
a |
| T1316 |
266-270 |
NN |
denotes |
role |
| T1317 |
271-273 |
IN |
denotes |
in |
| T1318 |
274-277 |
DT |
denotes |
the |
| T1319 |
278-288 |
NN |
denotes |
generation |
| T1320 |
289-292 |
CC |
denotes |
and |
| T1321 |
293-304 |
NN |
denotes |
propagation |
| T1322 |
305-307 |
IN |
denotes |
of |
| T1323 |
308-318 |
JJ |
denotes |
paroxysmal |
| T1324 |
319-327 |
NN |
denotes |
activity |
| T1325 |
328-330 |
IN |
denotes |
in |
| T1326 |
331-343 |
JJ |
denotes |
experimental |
| T1327 |
344-352 |
NN |
denotes |
epilepsy |
| T1328 |
353-359 |
NN |
denotes |
models |
| T1329 |
361-364 |
DT |
denotes |
The |
| T1330 |
365-373 |
NN |
denotes |
piriform |
| T1331 |
374-380 |
NN |
denotes |
cortex |
| T1332 |
381-382 |
-LRB- |
denotes |
( |
| T1333 |
382-384 |
NN |
denotes |
PC |
| T1334 |
384-385 |
-RRB- |
denotes |
) |
| T1335 |
386-388 |
VB |
denotes |
is |
| T1336 |
389-392 |
CD |
denotes |
one |
| T1337 |
393-395 |
IN |
denotes |
of |
| T1338 |
396-399 |
DT |
denotes |
the |
| T1339 |
400-404 |
RB |
denotes |
most |
| T1340 |
405-416 |
JJ |
denotes |
susceptible |
| T1341 |
417-422 |
NN |
denotes |
brain |
| T1342 |
423-430 |
NN |
denotes |
regions |
| T1343 |
431-433 |
TO |
denotes |
to |
| T1344 |
434-449 |
JJ |
denotes |
seizure-induced |
| T1345 |
450-456 |
NN |
denotes |
damage |
| T1346 |
457-459 |
IN |
denotes |
in |
| T1347 |
460-463 |
DT |
denotes |
the |
| T1348 |
464-471 |
NN |
denotes |
kainate |
| T1349 |
471-472 |
-COMMA- |
denotes |
, |
| T1350 |
473-484 |
NN |
denotes |
pilocarpine |
| T1351 |
485-488 |
CC |
denotes |
and |
| T1352 |
489-494 |
JJ |
denotes |
other |
| T1353 |
495-501 |
NN |
denotes |
models |
| T1354 |
502-504 |
IN |
denotes |
of |
| T1355 |
505-513 |
JJ |
denotes |
temporal |
| T1356 |
514-518 |
NN |
denotes |
lobe |
| T1357 |
519-527 |
NN |
denotes |
epilepsy |
| T1358 |
528-529 |
-LRB- |
denotes |
( |
| T1359 |
529-532 |
NN |
denotes |
TLE |
| T1360 |
532-533 |
-RRB- |
denotes |
) |
| T1361 |
534-535 |
-LRB- |
denotes |
[ |
| T1362 |
535-538 |
CD |
denotes |
4-6 |
| T1363 |
538-539 |
-RRB- |
denotes |
] |
| T1364 |
541-552 |
NN |
denotes |
Pilocarpine |
| T1365 |
552-553 |
-COMMA- |
denotes |
, |
| T1366 |
554-555 |
DT |
denotes |
a |
| T1367 |
556-567 |
JJ |
denotes |
cholinergic |
| T1368 |
568-575 |
NN |
denotes |
agonist |
| T1369 |
575-576 |
-COMMA- |
denotes |
, |
| T1370 |
577-584 |
VB |
denotes |
induces |
| T1371 |
585-587 |
NN |
denotes |
SE |
| T1372 |
588-590 |
IN |
denotes |
in |
| T1373 |
591-598 |
NN |
denotes |
rodents |
| T1374 |
600-604 |
DT |
denotes |
This |
| T1375 |
605-624 |
JJ |
denotes |
pilocarpine-induced |
| T1376 |
625-627 |
NN |
denotes |
SE |
| T1377 |
627-628 |
-COMMA- |
denotes |
, |
| T1378 |
629-636 |
JJ |
denotes |
similar |
| T1379 |
637-639 |
TO |
denotes |
to |
| T1380 |
640-645 |
JJ |
denotes |
human |
| T1381 |
646-649 |
NN |
denotes |
TLE |
| T1382 |
649-650 |
-COMMA- |
denotes |
, |
| T1383 |
651-656 |
VB |
denotes |
shows |
| T1384 |
657-664 |
JJ |
denotes |
massive |
| T1385 |
665-673 |
JJ |
denotes |
neuronal |
| T1386 |
674-678 |
NN |
denotes |
loss |
| T1387 |
679-681 |
IN |
denotes |
in |
| T1388 |
682-685 |
DT |
denotes |
the |
| T1389 |
686-697 |
NN |
denotes |
hippocampus |
| T1390 |
698-706 |
VB |
denotes |
followed |
| T1391 |
707-709 |
IN |
denotes |
by |
| T1392 |
710-715 |
JJ |
denotes |
glial |
| T1393 |
716-729 |
NN |
denotes |
proliferation |
| T1394 |
731-735 |
DT |
denotes |
This |
| T1395 |
736-744 |
JJ |
denotes |
neuronal |
| T1396 |
745-751 |
NN |
denotes |
damage |
| T1397 |
752-754 |
IN |
denotes |
in |
| T1398 |
755-758 |
DT |
denotes |
the |
| T1399 |
759-770 |
NN |
denotes |
pilocarpine |
| T1400 |
771-776 |
NN |
denotes |
model |
| T1401 |
777-779 |
VB |
denotes |
is |
| T1402 |
780-783 |
RB |
denotes |
not |
| T1403 |
784-794 |
JJ |
denotes |
restricted |
| T1404 |
795-797 |
TO |
denotes |
to |
| T1405 |
798-801 |
DT |
denotes |
the |
| T1406 |
802-813 |
NN |
denotes |
hippocampus |
| T1407 |
813-814 |
-COMMA- |
denotes |
, |
| T1408 |
815-818 |
CC |
denotes |
but |
| T1409 |
819-824 |
RB |
denotes |
often |
| T1410 |
825-832 |
VB |
denotes |
extends |
| T1411 |
833-835 |
TO |
denotes |
to |
| T1412 |
836-852 |
JJ |
denotes |
extrahippocampal |
| T1413 |
853-859 |
JJ |
denotes |
limbic |
| T1414 |
860-870 |
NN |
denotes |
structures |
| T1415 |
872-878 |
RB |
denotes |
Indeed |
| T1416 |
878-879 |
-COMMA- |
denotes |
, |
| T1417 |
880-899 |
JJ |
denotes |
pilocarpine-induced |
| T1418 |
900-902 |
NN |
denotes |
SE |
| T1419 |
903-910 |
VB |
denotes |
results |
| T1420 |
911-913 |
IN |
denotes |
in |
| T1421 |
914-919 |
JJ |
denotes |
acute |
| T1422 |
920-928 |
JJ |
denotes |
neuronal |
| T1423 |
929-936 |
NN |
denotes |
damages |
| T1424 |
937-943 |
IN |
denotes |
within |
| T1425 |
944-950 |
NN |
denotes |
layers |
| T1426 |
951-953 |
CD |
denotes |
II |
| T1427 |
954-957 |
CC |
denotes |
and |
| T1428 |
958-961 |
CD |
denotes |
III |
| T1429 |
962-964 |
IN |
denotes |
of |
| T1430 |
965-968 |
DT |
denotes |
the |
| T1431 |
969-971 |
NN |
denotes |
PC |
| T1432 |
972-973 |
-LRB- |
denotes |
[ |
| T1433 |
973-976 |
CD |
denotes |
5,6 |
| T1434 |
976-977 |
-RRB- |
denotes |
] |
| T1435 |
979-981 |
NN |
denotes |
SE |
| T1436 |
982-986 |
RB |
denotes |
also |
| T1437 |
987-994 |
VB |
denotes |
induces |
| T1438 |
995-1001 |
JJ |
denotes |
severe |
| T1439 |
1002-1011 |
JJ |
denotes |
vasogenic |
| T1440 |
1012-1017 |
NN |
denotes |
edema |
| T1441 |
1018-1020 |
IN |
denotes |
in |
| T1442 |
1021-1024 |
DT |
denotes |
the |
| T1443 |
1025-1027 |
NN |
denotes |
PC |
| T1444 |
1028-1039 |
VB |
denotes |
accompanied |
| T1445 |
1040-1042 |
IN |
denotes |
by |
| T1446 |
1043-1051 |
JJ |
denotes |
neuronal |
| T1447 |
1052-1055 |
CC |
denotes |
and |
| T1448 |
1056-1066 |
JJ |
denotes |
astroglial |
| T1449 |
1067-1074 |
NN |
denotes |
damages |
| T1450 |
1075-1076 |
-LRB- |
denotes |
[ |
| T1451 |
1076-1079 |
CD |
denotes |
5-8 |
| T1452 |
1079-1080 |
-RRB- |
denotes |
] |
| T1453 |
1082-1087 |
NN |
denotes |
Brain |
| T1454 |
1088-1093 |
NN |
denotes |
edema |
| T1455 |
1094-1102 |
NN |
denotes |
proceeds |
| T1456 |
1103-1105 |
IN |
denotes |
in |
| T1457 |
1106-1109 |
CD |
denotes |
two |
| T1458 |
1110-1116 |
NN |
denotes |
phases |
| T1459 |
1116-1117 |
-COMMA- |
denotes |
, |
| T1460 |
1118-1123 |
JJ |
denotes |
early |
| T1461 |
1124-1133 |
JJ |
denotes |
cytotoxic |
| T1462 |
1134-1139 |
NN |
denotes |
edema |
| T1463 |
1140-1145 |
NN |
denotes |
phase |
| T1464 |
1146-1149 |
CC |
denotes |
and |
| T1465 |
1150-1154 |
JJ |
denotes |
late |
| T1466 |
1155-1164 |
JJ |
denotes |
vasogenic |
| T1467 |
1165-1170 |
NN |
denotes |
edema |
| T1468 |
1171-1176 |
NN |
denotes |
phase |
| T1469 |
1178-1183 |
RB |
denotes |
Early |
| T1470 |
1184-1193 |
JJ |
denotes |
cytotoxic |
| T1471 |
1194-1201 |
JJ |
denotes |
osmotic |
| T1472 |
1202-1207 |
NN |
denotes |
edema |
| T1473 |
1208-1210 |
VB |
denotes |
is |
| T1474 |
1211-1214 |
JJ |
denotes |
due |
| T1475 |
1215-1217 |
TO |
denotes |
to |
| T1476 |
1218-1224 |
JJ |
denotes |
excess |
| T1477 |
1225-1236 |
NN |
denotes |
stimulation |
| T1478 |
1237-1239 |
IN |
denotes |
of |
| T1479 |
1240-1253 |
JJ |
denotes |
glutamatergic |
| T1480 |
1254-1262 |
NN |
denotes |
pathways |
| T1481 |
1263-1269 |
IN |
denotes |
during |
| T1482 |
1270-1272 |
NN |
denotes |
SE |
| T1483 |
1272-1273 |
-COMMA- |
denotes |
, |
| T1484 |
1274-1279 |
WDT |
denotes |
which |
| T1485 |
1280-1289 |
VB |
denotes |
increases |
| T1486 |
1290-1303 |
JJ |
denotes |
intracellular |
| T1487 |
1304-1307 |
NN |
denotes |
Na+ |
| T1488 |
1308-1311 |
CC |
denotes |
and |
| T1489 |
1312-1316 |
NN |
denotes |
Ca2+ |
| T1490 |
1317-1331 |
NN |
denotes |
concentrations |
| T1491 |
1333-1336 |
DT |
denotes |
The |
| T1492 |
1337-1346 |
JJ |
denotes |
vasogenic |
| T1493 |
1347-1352 |
NN |
denotes |
edema |
| T1494 |
1353-1360 |
VB |
denotes |
results |
| T1495 |
1361-1365 |
IN |
denotes |
from |
| T1496 |
1366-1377 |
NN |
denotes |
dysfunction |
| T1497 |
1378-1380 |
IN |
denotes |
of |
| T1498 |
1381-1392 |
JJ |
denotes |
endothelial |
| T1499 |
1393-1398 |
NN |
denotes |
cells |
| T1500 |
1399-1402 |
CC |
denotes |
and |
| T1501 |
1403-1406 |
DT |
denotes |
the |
| T1502 |
1407-1418 |
NN |
denotes |
blood-brain |
| T1503 |
1419-1426 |
NN |
denotes |
barrier |
| T1504 |
1427-1428 |
-LRB- |
denotes |
( |
| T1505 |
1428-1431 |
NN |
denotes |
BBB |
| T1506 |
1431-1432 |
-RRB- |
denotes |
) |
| T1507 |
1434-1438 |
JJ |
denotes |
Many |
| T1508 |
1439-1446 |
NN |
denotes |
studies |
| T1509 |
1447-1451 |
VB |
denotes |
have |
| T1510 |
1452-1460 |
VB |
denotes |
reported |
| T1511 |
1461-1470 |
VB |
denotes |
increased |
| T1512 |
1471-1483 |
NN |
denotes |
permeability |
| T1513 |
1484-1486 |
IN |
denotes |
of |
| T1514 |
1487-1490 |
DT |
denotes |
the |
| T1515 |
1491-1494 |
NNP |
denotes |
BBB |
| T1516 |
1495-1501 |
IN |
denotes |
during |
| T1517 |
1502-1511 |
JJ |
denotes |
epileptic |
| T1518 |
1512-1520 |
NN |
denotes |
activity |
| T1519 |
1521-1522 |
-LRB- |
denotes |
[ |
| T1520 |
1522-1526 |
CD |
denotes |
9-13 |
| T1521 |
1526-1527 |
-RRB- |
denotes |
] |
| T1522 |
1529-1530 |
DT |
denotes |
A |
| T1523 |
1531-1535 |
JJ |
denotes |
fast |
| T1524 |
1536-1539 |
CC |
denotes |
and |
| T1525 |
1540-1551 |
JJ |
denotes |
significant |
| T1526 |
1552-1560 |
NN |
denotes |
increase |
| T1527 |
1561-1563 |
IN |
denotes |
in |
| T1528 |
1564-1572 |
JJ |
denotes |
systemic |
| T1529 |
1573-1578 |
NN |
denotes |
blood |
| T1530 |
1579-1587 |
NN |
denotes |
pressure |
| T1531 |
1587-1588 |
-COMMA- |
denotes |
, |
| T1532 |
1589-1601 |
RB |
denotes |
particularly |
| T1533 |
1602-1607 |
VB |
denotes |
shown |
| T1534 |
1608-1614 |
IN |
denotes |
during |
| T1535 |
1615-1620 |
JJ |
denotes |
tonic |
| T1536 |
1621-1630 |
JJ |
denotes |
epileptic |
| T1537 |
1631-1639 |
NN |
denotes |
seizures |
| T1538 |
1639-1640 |
-COMMA- |
denotes |
, |
| T1539 |
1641-1648 |
VB |
denotes |
induces |
| T1540 |
1649-1650 |
DT |
denotes |
a |
| T1541 |
1651-1657 |
JJ |
denotes |
marked |
| T1542 |
1658-1670 |
NN |
denotes |
vasodilation |
| T1543 |
1671-1673 |
IN |
denotes |
of |
| T1544 |
1674-1677 |
DT |
denotes |
the |
| T1545 |
1678-1683 |
JJ |
denotes |
large |
| T1546 |
1684-1692 |
JJ |
denotes |
cerebral |
| T1547 |
1693-1701 |
NN |
denotes |
arteries |
| T1548 |
1702-1705 |
CC |
denotes |
and |
| T1549 |
1706-1708 |
DT |
denotes |
an |
| T1550 |
1709-1717 |
NN |
denotes |
increase |
| T1551 |
1718-1720 |
IN |
denotes |
in |
| T1552 |
1721-1726 |
NN |
denotes |
blood |
| T1553 |
1727-1735 |
NN |
denotes |
pressure |
| T1554 |
1736-1738 |
IN |
denotes |
in |
| T1555 |
1739-1750 |
NN |
denotes |
capillaries |
| T1556 |
1750-1751 |
-COMMA- |
denotes |
, |
| T1557 |
1752-1757 |
JJ |
denotes |
small |
| T1558 |
1758-1766 |
NN |
denotes |
arteries |
| T1559 |
1766-1767 |
-COMMA- |
denotes |
, |
| T1560 |
1768-1771 |
CC |
denotes |
and |
| T1561 |
1772-1777 |
NN |
denotes |
veins |
| T1562 |
1778-1785 |
VB |
denotes |
leading |
| T1563 |
1786-1788 |
TO |
denotes |
to |
| T1564 |
1789-1796 |
NN |
denotes |
leakage |
| T1565 |
1797-1799 |
IN |
denotes |
of |
| T1566 |
1800-1803 |
DT |
denotes |
the |
| T1567 |
1804-1807 |
NNP |
denotes |
BBB |
| T1568 |
1808-1809 |
-LRB- |
denotes |
[ |
| T1569 |
1809-1810 |
CD |
denotes |
9 |
| T1570 |
1810-1811 |
-RRB- |
denotes |
] |
| T1571 |
1813-1817 |
NN |
denotes |
Loss |
| T1572 |
1818-1820 |
IN |
denotes |
of |
| T1573 |
1821-1824 |
NN |
denotes |
BBB |
| T1574 |
1825-1834 |
NN |
denotes |
integrity |
| T1575 |
1835-1837 |
VB |
denotes |
is |
| T1576 |
1838-1841 |
RB |
denotes |
not |
| T1577 |
1842-1846 |
RB |
denotes |
only |
| T1578 |
1847-1850 |
JJ |
denotes |
due |
| T1579 |
1851-1853 |
TO |
denotes |
to |
| T1580 |
1854-1856 |
DT |
denotes |
an |
| T1581 |
1857-1863 |
JJ |
denotes |
abrupt |
| T1582 |
1864-1872 |
NN |
denotes |
increase |
| T1583 |
1873-1875 |
IN |
denotes |
in |
| T1584 |
1876-1879 |
DT |
denotes |
the |
| T1585 |
1880-1892 |
JJ |
denotes |
intraluminal |
| T1586 |
1893-1901 |
NN |
denotes |
pressure |
| T1587 |
1902-1905 |
CC |
denotes |
but |
| T1588 |
1906-1910 |
RB |
denotes |
also |
| T1589 |
1911-1921 |
VB |
denotes |
influenced |
| T1590 |
1922-1924 |
IN |
denotes |
by |
| T1591 |
1925-1928 |
DT |
denotes |
the |
| T1592 |
1929-1939 |
NN |
denotes |
properties |
| T1593 |
1940-1942 |
IN |
denotes |
of |
| T1594 |
1943-1951 |
JJ |
denotes |
cerebral |
| T1595 |
1952-1958 |
NN |
denotes |
tissue |
| T1596 |
1960-1966 |
RB |
denotes |
Indeed |
| T1597 |
1966-1967 |
-COMMA- |
denotes |
, |
| T1598 |
1968-1970 |
DT |
denotes |
an |
| T1599 |
1971-1976 |
JJ |
denotes |
acute |
| T1600 |
1977-1985 |
NN |
denotes |
increase |
| T1601 |
1986-1988 |
IN |
denotes |
in |
| T1602 |
1989-1994 |
NN |
denotes |
blood |
| T1603 |
1995-2003 |
NN |
denotes |
pressure |
| T1604 |
2004-2006 |
CC |
denotes |
or |
| T1605 |
2007-2016 |
JJ |
denotes |
epileptic |
| T1606 |
2017-2025 |
NN |
denotes |
activity |
| T1607 |
2026-2032 |
VB |
denotes |
causes |
| T1608 |
2033-2035 |
DT |
denotes |
an |
| T1609 |
2036-2044 |
NN |
denotes |
increase |
| T1610 |
2045-2047 |
IN |
denotes |
in |
| T1611 |
2048-2059 |
NN |
denotes |
pinocytosis |
| T1612 |
2060-2062 |
IN |
denotes |
at |
| T1613 |
2063-2066 |
DT |
denotes |
the |
| T1614 |
2067-2072 |
NN |
denotes |
level |
| T1615 |
2073-2075 |
IN |
denotes |
of |
| T1616 |
2076-2079 |
DT |
denotes |
the |
| T1617 |
2080-2088 |
JJ |
denotes |
cerebral |
| T1618 |
2089-2100 |
NN |
denotes |
endothelium |
| T1619 |
2101-2102 |
-LRB- |
denotes |
[ |
| T1620 |
2102-2107 |
CD |
denotes |
11-13 |
| T1621 |
2107-2108 |
-RRB- |
denotes |
] |
| T1622 |
2110-2118 |
RB |
denotes |
Recently |
| T1623 |
2118-2119 |
-COMMA- |
denotes |
, |
| T1624 |
2120-2127 |
NN |
denotes |
reports |
| T1625 |
2128-2132 |
VB |
denotes |
have |
| T1626 |
2133-2137 |
RB |
denotes |
also |
| T1627 |
2138-2148 |
VB |
denotes |
emphasized |
| T1628 |
2149-2153 |
IN |
denotes |
that |
| T1629 |
2154-2161 |
NN |
denotes |
seizure |
| T1630 |
2162-2164 |
CC |
denotes |
or |
| T1631 |
2165-2173 |
NN |
denotes |
epilepsy |
| T1632 |
2174-2176 |
VB |
denotes |
is |
| T1633 |
2177-2178 |
DT |
denotes |
a |
| T1634 |
2179-2188 |
JJ |
denotes |
prolonged |
| T1635 |
2189-2201 |
JJ |
denotes |
inflammatory |
| T1636 |
2202-2211 |
NN |
denotes |
condition |
| T1637 |
2211-2212 |
-COMMA- |
denotes |
, |
| T1638 |
2213-2216 |
CC |
denotes |
and |
| T1639 |
2217-2221 |
IN |
denotes |
that |
| T1640 |
2222-2229 |
NN |
denotes |
seizure |
| T1641 |
2230-2238 |
NN |
denotes |
activity |
| T1642 |
2239-2246 |
RB |
denotes |
rapidly |
| T1643 |
2247-2256 |
VB |
denotes |
increases |
| T1644 |
2257-2260 |
DT |
denotes |
the |
| T1645 |
2261-2270 |
NN |
denotes |
synthesis |
| T1646 |
2271-2274 |
CC |
denotes |
and |
| T1647 |
2275-2282 |
NN |
denotes |
release |
| T1648 |
2283-2285 |
IN |
denotes |
of |
| T1649 |
2286-2293 |
JJ |
denotes |
various |
| T1650 |
2294-2306 |
NN |
denotes |
interleukins |
| T1651 |
2307-2309 |
IN |
denotes |
in |
| T1652 |
2310-2316 |
NN |
denotes |
rodent |
| T1653 |
2317-2322 |
NN |
denotes |
brain |
| T1654 |
2323-2328 |
NN |
denotes |
areas |
| T1655 |
2329-2337 |
VB |
denotes |
involved |
| T1656 |
2338-2340 |
IN |
denotes |
in |
| T1657 |
2341-2348 |
NN |
denotes |
seizure |
| T1658 |
2349-2354 |
NN |
denotes |
onset |
| T1659 |
2355-2358 |
CC |
denotes |
and |
| T1660 |
2359-2364 |
PRP-DOLLAR- |
denotes |
their |
| T1661 |
2365-2379 |
NN |
denotes |
generalization |
| T1662 |
2381-2390 |
NN |
denotes |
Cytokines |
| T1663 |
2391-2394 |
VB |
denotes |
act |
| T1664 |
2395-2397 |
IN |
denotes |
on |
| T1665 |
2398-2409 |
JJ |
denotes |
endothelial |
| T1666 |
2410-2415 |
NN |
denotes |
cells |
| T1667 |
2416-2419 |
CC |
denotes |
and |
| T1668 |
2420-2426 |
VB |
denotes |
change |
| T1669 |
2427-2430 |
DT |
denotes |
the |
| T1670 |
2431-2443 |
NN |
denotes |
permeability |
| T1671 |
2444-2446 |
IN |
denotes |
of |
| T1672 |
2447-2450 |
DT |
denotes |
the |
| T1673 |
2451-2454 |
NNP |
denotes |
BBB |
| T1674 |
2454-2455 |
-COMMA- |
denotes |
, |
| T1675 |
2456-2461 |
WDT |
denotes |
which |
| T1676 |
2462-2468 |
VB |
denotes |
exerts |
| T1677 |
2469-2480 |
JJ |
denotes |
significant |
| T1678 |
2481-2488 |
NN |
denotes |
effects |
| T1679 |
2489-2491 |
IN |
denotes |
on |
| T1680 |
2492-2500 |
JJ |
denotes |
neuronal |
| T1681 |
2501-2510 |
NN |
denotes |
viability |
| T1682 |
2511-2514 |
CC |
denotes |
and |
| T1683 |
2515-2527 |
NN |
denotes |
excitability |
| T1684 |
2528-2529 |
-LRB- |
denotes |
[ |
| T1685 |
2529-2534 |
CD |
denotes |
14,15 |
| T1686 |
2534-2535 |
-RRB- |
denotes |
] |
| T1687 |
2537-2543 |
RB |
denotes |
Indeed |
| T1688 |
2543-2544 |
-COMMA- |
denotes |
, |
| T1689 |
2545-2552 |
NNP |
denotes |
Sztriha |
| T1690 |
2553-2554 |
-LRB- |
denotes |
[ |
| T1691 |
2554-2556 |
CD |
denotes |
16 |
| T1692 |
2556-2557 |
-RRB- |
denotes |
] |
| T1693 |
2558-2566 |
VB |
denotes |
reported |
| T1694 |
2567-2571 |
IN |
denotes |
that |
| T1695 |
2572-2585 |
NN |
denotes |
dexamethasone |
| T1696 |
2586-2598 |
NN |
denotes |
pretreatment |
| T1697 |
2599-2606 |
VB |
denotes |
reduces |
| T1698 |
2607-2616 |
JJ |
denotes |
vasogenic |
| T1699 |
2617-2622 |
NN |
denotes |
edema |
| T1700 |
2623-2625 |
IN |
denotes |
in |
| T1701 |
2626-2634 |
NN |
denotes |
thalamus |
| T1702 |
2635-2644 |
VB |
denotes |
following |
| T1703 |
2645-2651 |
JJ |
denotes |
kainic |
| T1704 |
2652-2664 |
JJ |
denotes |
acid-induced |
| T1705 |
2665-2672 |
NN |
denotes |
seizure |
| T1706 |
2674-2679 |
IN |
denotes |
Among |
| T1707 |
2680-2689 |
NN |
denotes |
cytokines |
| T1708 |
2689-2690 |
-COMMA- |
denotes |
, |
| T1709 |
2691-2696 |
NN |
denotes |
tumor |
| T1710 |
2697-2705 |
NN |
denotes |
necrosis |
| T1711 |
2706-2714 |
NN |
denotes |
factor-α |
| T1712 |
2715-2716 |
-LRB- |
denotes |
( |
| T1713 |
2716-2721 |
NN |
denotes |
TNF-α |
| T1714 |
2721-2722 |
-RRB- |
denotes |
) |
| T1715 |
2723-2725 |
VB |
denotes |
is |
| T1716 |
2726-2727 |
DT |
denotes |
a |
| T1717 |
2728-2730 |
CD |
denotes |
17 |
| T1718 |
2731-2734 |
NN |
denotes |
kDa |
| T1719 |
2735-2742 |
NN |
denotes |
protein |
| T1720 |
2743-2747 |
WDT |
denotes |
that |
| T1721 |
2748-2750 |
VB |
denotes |
is |
| T1722 |
2751-2759 |
VB |
denotes |
produced |
| T1723 |
2760-2766 |
RB |
denotes |
mainly |
| T1724 |
2767-2769 |
IN |
denotes |
by |
| T1725 |
2770-2779 |
VB |
denotes |
activated |
| T1726 |
2780-2791 |
NN |
denotes |
macrophages |
| T1727 |
2792-2795 |
CC |
denotes |
and |
| T1728 |
2796-2797 |
NN |
denotes |
T |
| T1729 |
2798-2803 |
NN |
denotes |
cells |
| T1730 |
2804-2806 |
IN |
denotes |
in |
| T1731 |
2807-2810 |
DT |
denotes |
the |
| T1732 |
2811-2817 |
JJ |
denotes |
immune |
| T1733 |
2818-2824 |
NN |
denotes |
system |
| T1734 |
2826-2831 |
NN |
denotes |
TNF-α |
| T1735 |
2832-2834 |
VB |
denotes |
is |
| T1736 |
2835-2844 |
VB |
denotes |
expressed |
| T1737 |
2845-2847 |
IN |
denotes |
at |
| T1738 |
2848-2851 |
JJ |
denotes |
low |
| T1739 |
2852-2858 |
NN |
denotes |
levels |
| T1740 |
2859-2861 |
IN |
denotes |
in |
| T1741 |
2862-2868 |
JJ |
denotes |
normal |
| T1742 |
2869-2874 |
NN |
denotes |
brain |
| T1743 |
2875-2878 |
CC |
denotes |
and |
| T1744 |
2879-2881 |
VB |
denotes |
is |
| T1745 |
2882-2889 |
RB |
denotes |
rapidly |
| T1746 |
2890-2901 |
VB |
denotes |
upregulated |
| T1747 |
2902-2904 |
IN |
denotes |
in |
| T1748 |
2905-2909 |
NN |
denotes |
glia |
| T1749 |
2909-2910 |
-COMMA- |
denotes |
, |
| T1750 |
2911-2918 |
NN |
denotes |
neurons |
| T1751 |
2919-2922 |
CC |
denotes |
and |
| T1752 |
2923-2934 |
JJ |
denotes |
endothelial |
| T1753 |
2935-2940 |
NN |
denotes |
cells |
| T1754 |
2941-2943 |
IN |
denotes |
in |
| T1755 |
2944-2951 |
JJ |
denotes |
various |
| T1756 |
2952-2970 |
JJ |
denotes |
pathophysiological |
| T1757 |
2971-2981 |
NN |
denotes |
conditions |
| T1758 |
2981-2982 |
-COMMA- |
denotes |
, |
| T1759 |
2983-2992 |
VB |
denotes |
including |
| T1760 |
2993-2995 |
NN |
denotes |
SE |
| T1761 |
2996-2997 |
-LRB- |
denotes |
[ |
| T1762 |
2997-3002 |
CD |
denotes |
17,18 |
| T1763 |
3002-3003 |
-RRB- |
denotes |
] |
| T1764 |
3005-3010 |
NN |
denotes |
TNF-α |
| T1765 |
3011-3016 |
VB |
denotes |
shows |
| T1766 |
3017-3024 |
JJ |
denotes |
various |
| T1767 |
3025-3032 |
NN |
denotes |
effects |
| T1768 |
3033-3035 |
IN |
denotes |
on |
| T1769 |
3036-3041 |
NN |
denotes |
brain |
| T1770 |
3042-3050 |
NN |
denotes |
function |
| T1771 |
3051-3060 |
VB |
denotes |
depending |
| T1772 |
3061-3063 |
IN |
denotes |
on |
| T1773 |
3064-3067 |
PRP-DOLLAR- |
denotes |
its |
| T1774 |
3068-3073 |
JJ |
denotes |
local |
| T1775 |
3074-3080 |
NN |
denotes |
tissue |
| T1776 |
3081-3094 |
NN |
denotes |
concentration |
| T1777 |
3094-3095 |
-COMMA- |
denotes |
, |
| T1778 |
3096-3099 |
DT |
denotes |
the |
| T1779 |
3100-3104 |
NN |
denotes |
type |
| T1780 |
3105-3107 |
IN |
denotes |
of |
| T1781 |
3108-3114 |
NN |
denotes |
target |
| T1782 |
3115-3120 |
NN |
denotes |
cells |
| T1783 |
3120-3121 |
-COMMA- |
denotes |
, |
| T1784 |
3122-3125 |
CC |
denotes |
and |
| T1785 |
3126-3136 |
RB |
denotes |
especially |
| T1786 |
3137-3140 |
DT |
denotes |
the |
| T1787 |
3141-3149 |
JJ |
denotes |
specific |
| T1788 |
3150-3158 |
NN |
denotes |
receptor |
| T1789 |
3159-3166 |
NN |
denotes |
subtype |
| T1790 |
3166-3167 |
-COLON- |
denotes |
: |
| T1791 |
3168-3171 |
NN |
denotes |
TNF |
| T1792 |
3172-3180 |
NN |
denotes |
receptor |
| T1793 |
3181-3182 |
NN |
denotes |
I |
| T1794 |
3182-3183 |
-COMMA- |
denotes |
, |
| T1795 |
3184-3186 |
CC |
denotes |
or |
| T1796 |
3187-3190 |
NN |
denotes |
p55 |
| T1797 |
3191-3199 |
NN |
denotes |
receptor |
| T1798 |
3200-3201 |
-LRB- |
denotes |
( |
| T1799 |
3201-3208 |
NN |
denotes |
TNFp55R |
| T1800 |
3208-3209 |
-RRB- |
denotes |
) |
| T1801 |
3209-3210 |
-COLON- |
denotes |
; |
| T1802 |
3211-3214 |
CC |
denotes |
and |
| T1803 |
3215-3218 |
NN |
denotes |
TNF |
| T1804 |
3219-3227 |
NN |
denotes |
receptor |
| T1805 |
3228-3230 |
CD |
denotes |
II |
| T1806 |
3230-3231 |
-COMMA- |
denotes |
, |
| T1807 |
3232-3234 |
CC |
denotes |
or |
| T1808 |
3235-3238 |
NN |
denotes |
p75 |
| T1809 |
3239-3247 |
NN |
denotes |
receptor |
| T1810 |
3248-3249 |
-LRB- |
denotes |
( |
| T1811 |
3249-3256 |
NN |
denotes |
TNFp75R |
| T1812 |
3256-3257 |
-RRB- |
denotes |
) |
| T1813 |
3258-3259 |
-LRB- |
denotes |
[ |
| T1814 |
3259-3261 |
CD |
denotes |
19 |
| T1815 |
3261-3262 |
-RRB- |
denotes |
] |
| T1816 |
3264-3275 |
RB |
denotes |
Furthermore |
| T1817 |
3275-3276 |
-COMMA- |
denotes |
, |
| T1818 |
3277-3282 |
NN |
denotes |
TNF-α |
| T1819 |
3283-3290 |
VB |
denotes |
induces |
| T1820 |
3291-3301 |
NN |
denotes |
macrophage |
| T1821 |
3302-3314 |
JJ |
denotes |
inflammatory |
| T1822 |
3315-3324 |
NN |
denotes |
protein-2 |
| T1823 |
3325-3326 |
-LRB- |
denotes |
( |
| T1824 |
3326-3331 |
NN |
denotes |
MIP-2 |
| T1825 |
3331-3332 |
-RRB- |
denotes |
) |
| T1826 |
3333-3337 |
WDT |
denotes |
that |
| T1827 |
3338-3346 |
VB |
denotes |
recruits |
| T1828 |
3347-3358 |
NN |
denotes |
neutrophils |
| T1829 |
3359-3364 |
IN |
denotes |
under |
| T1830 |
3365-3377 |
JJ |
denotes |
pathological |
| T1831 |
3378-3388 |
NN |
denotes |
conditions |
| T1832 |
3388-3389 |
-COMMA- |
denotes |
, |
| T1833 |
3390-3399 |
VB |
denotes |
including |
| T1834 |
3400-3402 |
NN |
denotes |
SE |
| T1835 |
3403-3404 |
-LRB- |
denotes |
[ |
| T1836 |
3404-3409 |
CD |
denotes |
14,20 |
| T1837 |
3409-3410 |
-RRB- |
denotes |
] |
| T1838 |
3412-3419 |
NN |
denotes |
Neurons |
| T1839 |
3419-3420 |
-COMMA- |
denotes |
, |
| T1840 |
3421-3430 |
NN |
denotes |
microglia |
| T1841 |
3430-3431 |
-COMMA- |
denotes |
, |
| T1842 |
3432-3435 |
CC |
denotes |
and |
| T1843 |
3436-3446 |
NN |
denotes |
astrocytes |
| T1844 |
3447-3454 |
VB |
denotes |
produce |
| T1845 |
3455-3460 |
NN |
denotes |
MIP-2 |
| T1846 |
3461-3465 |
WRB |
denotes |
when |
| T1847 |
3466-3475 |
VB |
denotes |
incubated |
| T1848 |
3476-3480 |
IN |
denotes |
with |
| T1849 |
3481-3497 |
JJ |
denotes |
pro-inflammatory |
| T1850 |
3498-3507 |
NN |
denotes |
cytokines |
| T1851 |
3508-3512 |
JJ |
denotes |
such |
| T1852 |
3513-3515 |
IN |
denotes |
as |
| T1853 |
3516-3521 |
NN |
denotes |
TNF-α |
| T1854 |
3522-3528 |
CC |
denotes |
and/or |
| T1855 |
3529-3543 |
NN |
denotes |
interleukin-1β |
| T1856 |
3544-3545 |
-LRB- |
denotes |
( |
| T1857 |
3545-3550 |
NN |
denotes |
IL-1β |
| T1858 |
3550-3551 |
-RRB- |
denotes |
) |
| T1859 |
3552-3554 |
CC |
denotes |
or |
| T1860 |
3555-3560 |
IN |
denotes |
after |
| T1861 |
3561-3567 |
NN |
denotes |
injury |
| T1862 |
3568-3569 |
-LRB- |
denotes |
[ |
| T1863 |
3569-3574 |
CD |
denotes |
21-23 |
| T1864 |
3574-3575 |
-RRB- |
denotes |
] |
| T1865 |
3577-3583 |
RB |
denotes |
Indeed |
| T1866 |
3583-3584 |
-COMMA- |
denotes |
, |
| T1867 |
3585-3587 |
PRP |
denotes |
we |
| T1868 |
3588-3592 |
VB |
denotes |
have |
| T1869 |
3593-3601 |
RB |
denotes |
recently |
| T1870 |
3602-3610 |
VB |
denotes |
reported |
| T1871 |
3611-3615 |
IN |
denotes |
that |
| T1872 |
3616-3627 |
JJ |
denotes |
SE-mediated |
| T1873 |
3628-3633 |
NN |
denotes |
MIP-2 |
| T1874 |
3634-3644 |
NN |
denotes |
expression |
| T1875 |
3645-3647 |
VB |
denotes |
is |
| T1876 |
3648-3656 |
JJ |
denotes |
relevant |
| T1877 |
3657-3659 |
TO |
denotes |
to |
| T1878 |
3660-3669 |
NN |
denotes |
leukocyte |
| T1879 |
3670-3683 |
NN |
denotes |
infiltrations |
| T1880 |
3684-3693 |
VB |
denotes |
following |
| T1881 |
3694-3696 |
NN |
denotes |
SE |
| T1882 |
3697-3699 |
IN |
denotes |
in |
| T1883 |
3700-3702 |
DT |
denotes |
an |
| T1884 |
3703-3720 |
JJ |
denotes |
IL-1β-independent |
| T1885 |
3721-3727 |
NN |
denotes |
manner |
| T1886 |
3728-3729 |
-LRB- |
denotes |
[ |
| T1887 |
3729-3731 |
CD |
denotes |
20 |
| T1888 |
3731-3732 |
-RRB- |
denotes |
] |
| T1889 |
3734-3741 |
RB |
denotes |
However |
| T1890 |
3741-3742 |
-COMMA- |
denotes |
, |
| T1891 |
3743-3746 |
DT |
denotes |
the |
| T1892 |
3747-3759 |
NN |
denotes |
relationship |
| T1893 |
3760-3767 |
IN |
denotes |
between |
| T1894 |
3768-3771 |
DT |
denotes |
the |
| T1895 |
3772-3777 |
NN |
denotes |
TNF-α |
| T1896 |
3778-3784 |
NN |
denotes |
system |
| T1897 |
3785-3788 |
CC |
denotes |
and |
| T1898 |
3789-3792 |
NN |
denotes |
BBB |
| T1899 |
3793-3814 |
NN |
denotes |
disruption/neutrophil |
| T1900 |
3815-3827 |
NN |
denotes |
infiltration |
| T1901 |
3828-3834 |
IN |
denotes |
during |
| T1902 |
3835-3844 |
JJ |
denotes |
vasogenic |
| T1903 |
3845-3850 |
NN |
denotes |
edema |
| T1904 |
3851-3860 |
NN |
denotes |
formation |
| T1905 |
3861-3868 |
VB |
denotes |
induced |
| T1906 |
3869-3871 |
IN |
denotes |
by |
| T1907 |
3872-3885 |
JJ |
denotes |
epileptogenic |
| T1908 |
3886-3893 |
NN |
denotes |
insults |
| T1909 |
3894-3897 |
VB |
denotes |
has |
| T1910 |
3898-3901 |
RB |
denotes |
not |
| T1911 |
3902-3906 |
VB |
denotes |
been |
| T1912 |
3907-3912 |
RB |
denotes |
fully |
| T1913 |
3913-3922 |
VB |
denotes |
clarified |
| T1914 |
3924-3933 |
RB |
denotes |
Therefore |
| T1915 |
3933-3934 |
-COMMA- |
denotes |
, |
| T1916 |
3935-3937 |
IN |
denotes |
in |
| T1917 |
3938-3941 |
DT |
denotes |
the |
| T1918 |
3942-3949 |
JJ |
denotes |
present |
| T1919 |
3950-3955 |
NN |
denotes |
study |
| T1920 |
3955-3956 |
-COMMA- |
denotes |
, |
| T1921 |
3957-3959 |
PRP |
denotes |
we |
| T1922 |
3960-3972 |
VB |
denotes |
investigated |
| T1923 |
3973-3976 |
DT |
denotes |
the |
| T1924 |
3977-3982 |
NN |
denotes |
roles |
| T1925 |
3983-3985 |
IN |
denotes |
of |
| T1926 |
3986-3991 |
NN |
denotes |
TNF-α |
| T1927 |
3992-3994 |
IN |
denotes |
in |
| T1928 |
3995-4004 |
JJ |
denotes |
vasogenic |
| T1929 |
4005-4010 |
NN |
denotes |
edema |
| T1930 |
4011-4014 |
CC |
denotes |
and |
| T1931 |
4015-4018 |
PRP-DOLLAR- |
denotes |
its |
| T1932 |
4019-4026 |
JJ |
denotes |
related |
| T1933 |
4027-4033 |
NN |
denotes |
events |
| T1934 |
4034-4036 |
IN |
denotes |
in |
| T1935 |
4037-4040 |
NN |
denotes |
rat |
| T1936 |
4041-4049 |
NN |
denotes |
epilepsy |
| T1937 |
4050-4056 |
NN |
denotes |
models |
| T1938 |
4057-4065 |
VB |
denotes |
provoked |
| T1939 |
4066-4068 |
IN |
denotes |
by |
| T1940 |
4069-4088 |
JJ |
denotes |
pilocarpine-induced |
| T1941 |
4089-4091 |
NN |
denotes |
SE |
| R1000 |
T1564 |
T1565 |
arg1Of |
leakage,of |
| R1001 |
T1567 |
T1565 |
arg2Of |
BBB,of |
| R1002 |
T1567 |
T1566 |
arg1Of |
BBB,the |
| R1003 |
T1567 |
T1568 |
arg1Of |
BBB,[ |
| R1004 |
T1569 |
T1568 |
arg2Of |
9,[ |
| R1005 |
T1570 |
T1568 |
arg3Of |
],[ |
| R1006 |
T1571 |
T1572 |
arg1Of |
Loss,of |
| R1007 |
T1571 |
T1575 |
arg1Of |
Loss,is |
| R1008 |
T1571 |
T1578 |
arg1Of |
Loss,due |
| R1009 |
T1571 |
T1588 |
arg1Of |
Loss,also |
| R1010 |
T1571 |
T1589 |
arg2Of |
Loss,influenced |
| R1011 |
T1574 |
T1572 |
arg2Of |
integrity,of |
| R1012 |
T1574 |
T1573 |
arg1Of |
integrity,BBB |
| R1013 |
T1575 |
T1589 |
modOf |
is,influenced |
| R1014 |
T1577 |
T1576 |
arg1Of |
only,not |
| R1015 |
T1578 |
T1577 |
arg1Of |
due,only |
| R1016 |
T1578 |
T1579 |
arg1Of |
due,to |
| R1017 |
T1578 |
T1587 |
arg1Of |
due,but |
| R1018 |
T1582 |
T1579 |
arg2Of |
increase,to |
| R1019 |
T1582 |
T1580 |
arg1Of |
increase,an |
| R1020 |
T1582 |
T1581 |
arg1Of |
increase,abrupt |
| R1021 |
T1582 |
T1583 |
arg1Of |
increase,in |
| R1022 |
T1586 |
T1583 |
arg2Of |
pressure,in |
| R1023 |
T1586 |
T1584 |
arg1Of |
pressure,the |
| R1024 |
T1586 |
T1585 |
arg1Of |
pressure,intraluminal |
| R1025 |
T1587 |
T1575 |
arg2Of |
but,is |
| R1026 |
T1588 |
T1587 |
arg2Of |
also,but |
| R1027 |
T1592 |
T1589 |
arg1Of |
properties,influenced |
| R1028 |
T1592 |
T1590 |
arg2Of |
properties,by |
| R1029 |
T1592 |
T1591 |
arg1Of |
properties,the |
| R1030 |
T1592 |
T1593 |
arg1Of |
properties,of |
| R1031 |
T1595 |
T1593 |
arg2Of |
tissue,of |
| R1032 |
T1595 |
T1594 |
arg1Of |
tissue,cerebral |
| R1033 |
T1600 |
T1598 |
arg1Of |
increase,an |
| R1034 |
T1600 |
T1599 |
arg1Of |
increase,acute |
| R1035 |
T1600 |
T1601 |
arg1Of |
increase,in |
| R1036 |
T1600 |
T1607 |
arg1Of |
increase,causes |
| R1037 |
T1603 |
T1602 |
arg1Of |
pressure,blood |
| R1038 |
T1603 |
T1604 |
arg1Of |
pressure,or |
| R1039 |
T1604 |
T1601 |
arg2Of |
or,in |
| R1040 |
T1606 |
T1604 |
arg2Of |
activity,or |
| R1041 |
T1606 |
T1605 |
arg1Of |
activity,epileptic |
| R1042 |
T1607 |
T1596 |
arg1Of |
causes,Indeed |
| R1043 |
T1607 |
T1597 |
arg1Of |
causes,"," |
| R1044 |
T1609 |
T1607 |
arg2Of |
increase,causes |
| R1045 |
T1609 |
T1608 |
arg1Of |
increase,an |
| R1046 |
T1609 |
T1610 |
arg1Of |
increase,in |
| R1047 |
T1609 |
T1612 |
arg1Of |
increase,at |
| R1048 |
T1611 |
T1610 |
arg2Of |
pinocytosis,in |
| R1049 |
T1614 |
T1612 |
arg2Of |
level,at |
| R1050 |
T1614 |
T1613 |
arg1Of |
level,the |
| R1051 |
T1614 |
T1615 |
arg1Of |
level,of |
| R1052 |
T1618 |
T1615 |
arg2Of |
endothelium,of |
| R1053 |
T1618 |
T1616 |
arg1Of |
endothelium,the |
| R1054 |
T1618 |
T1617 |
arg1Of |
endothelium,cerebral |
| R1055 |
T1618 |
T1619 |
arg1Of |
endothelium,[ |
| R1056 |
T1620 |
T1619 |
arg2Of |
11-13,[ |
| R1057 |
T1621 |
T1619 |
arg3Of |
],[ |
| R1058 |
T1624 |
T1625 |
arg1Of |
reports,have |
| R1059 |
T1624 |
T1627 |
arg1Of |
reports,emphasized |
| R1060 |
T1627 |
T1622 |
arg1Of |
emphasized,Recently |
| R1061 |
T1627 |
T1623 |
arg1Of |
emphasized,"," |
| R1062 |
T1627 |
T1625 |
arg2Of |
emphasized,have |
| R1063 |
T1627 |
T1626 |
arg1Of |
emphasized,also |
| R1064 |
T1629 |
T1630 |
arg1Of |
seizure,or |
| R1065 |
T1630 |
T1632 |
arg1Of |
or,is |
| R1066 |
T1631 |
T1630 |
arg2Of |
epilepsy,or |
| R1067 |
T1632 |
T1628 |
arg1Of |
is,that |
| R1068 |
T1632 |
T1638 |
arg1Of |
is,and |
| R1069 |
T1636 |
T1632 |
arg2Of |
condition,is |
| R1070 |
T1636 |
T1633 |
arg1Of |
condition,a |
| R1071 |
T1636 |
T1634 |
arg1Of |
condition,prolonged |
| R1072 |
T1636 |
T1635 |
arg1Of |
condition,inflammatory |
| R1073 |
T1638 |
T1627 |
arg2Of |
and,emphasized |
| R1074 |
T1638 |
T1637 |
arg1Of |
and,"," |
| R1075 |
T1639 |
T1638 |
arg2Of |
that,and |
| R1076 |
T1641 |
T1640 |
arg1Of |
activity,seizure |
| R1077 |
T1641 |
T1643 |
arg1Of |
activity,increases |
| R1078 |
T1643 |
T1639 |
arg2Of |
increases,that |
| R1079 |
T1643 |
T1642 |
arg1Of |
increases,rapidly |
| R1080 |
T1645 |
T1646 |
arg1Of |
synthesis,and |
| R1081 |
T1646 |
T1643 |
arg2Of |
and,increases |
| R1082 |
T1646 |
T1644 |
arg1Of |
and,the |
| R1083 |
T1646 |
T1648 |
arg1Of |
and,of |
| R1084 |
T1646 |
T1651 |
arg1Of |
and,in |
| R1085 |
T1647 |
T1646 |
arg2Of |
release,and |
| R1086 |
T1650 |
T1648 |
arg2Of |
interleukins,of |
| R1087 |
T1650 |
T1649 |
arg1Of |
interleukins,various |
| R1088 |
T1654 |
T1651 |
arg2Of |
areas,in |
| R1089 |
T1654 |
T1652 |
arg1Of |
areas,rodent |
| R1090 |
T1654 |
T1653 |
arg1Of |
areas,brain |
| R1091 |
T1654 |
T1655 |
arg2Of |
areas,involved |
| R1092 |
T1655 |
T1656 |
arg1Of |
involved,in |
| R1093 |
T1658 |
T1657 |
arg1Of |
onset,seizure |
| R1094 |
T1658 |
T1659 |
arg1Of |
onset,and |
| R1095 |
T1659 |
T1656 |
arg2Of |
and,in |
| R1096 |
T1661 |
T1659 |
arg2Of |
generalization,and |
| R1097 |
T1661 |
T1660 |
arg1Of |
generalization,their |
| R1098 |
T1662 |
T1663 |
arg1Of |
Cytokines,act |
| R1099 |
T1662 |
T1668 |
arg1Of |
Cytokines,change |
| R1100 |
T1663 |
T1664 |
arg1Of |
act,on |
| R1101 |
T1663 |
T1667 |
arg1Of |
act,and |
| R1102 |
T1666 |
T1664 |
arg2Of |
cells,on |
| R1103 |
T1666 |
T1665 |
arg1Of |
cells,endothelial |
| R1104 |
T1668 |
T1667 |
arg2Of |
change,and |
| R1105 |
T1670 |
T1668 |
arg2Of |
permeability,change |
| R1106 |
T1670 |
T1669 |
arg1Of |
permeability,the |
| R1107 |
T1670 |
T1671 |
arg1Of |
permeability,of |
| R1108 |
T1673 |
T1671 |
arg2Of |
BBB,of |
| R1109 |
T1673 |
T1672 |
arg1Of |
BBB,the |
| R1110 |
T1673 |
T1674 |
arg1Of |
BBB,"," |
| R1111 |
T1673 |
T1675 |
arg1Of |
BBB,which |
| R1112 |
T1673 |
T1676 |
arg1Of |
BBB,exerts |
| R1113 |
T1676 |
T1679 |
arg1Of |
exerts,on |
| R1114 |
T1678 |
T1676 |
arg2Of |
effects,exerts |
| R1115 |
T1678 |
T1677 |
arg1Of |
effects,significant |
| R1116 |
T1681 |
T1680 |
arg1Of |
viability,neuronal |
| R1117 |
T1681 |
T1682 |
arg1Of |
viability,and |
| R1118 |
T1682 |
T1679 |
arg2Of |
and,on |
| R1119 |
T1683 |
T1682 |
arg2Of |
excitability,and |
| R1120 |
T1683 |
T1684 |
arg1Of |
excitability,[ |
| R1121 |
T1685 |
T1684 |
arg2Of |
"14,15",[ |
| R1122 |
T1686 |
T1684 |
arg3Of |
],[ |
| R1123 |
T1689 |
T1690 |
arg1Of |
Sztriha,[ |
| R1124 |
T1689 |
T1693 |
arg1Of |
Sztriha,reported |
| R1125 |
T1691 |
T1690 |
arg2Of |
16,[ |
| R1126 |
T1692 |
T1690 |
arg3Of |
],[ |
| R1127 |
T1693 |
T1687 |
arg1Of |
reported,Indeed |
| R1128 |
T1693 |
T1688 |
arg1Of |
reported,"," |
| R1129 |
T1696 |
T1695 |
arg1Of |
pretreatment,dexamethasone |
| R1130 |
T1696 |
T1697 |
arg1Of |
pretreatment,reduces |
| R1131 |
T1697 |
T1693 |
arg2Of |
reduces,reported |
| R1132 |
T1697 |
T1694 |
arg1Of |
reduces,that |
| R1133 |
T1699 |
T1697 |
arg2Of |
edema,reduces |
| R1134 |
T1699 |
T1698 |
arg1Of |
edema,vasogenic |
| R1135 |
T1699 |
T1700 |
arg1Of |
edema,in |
| R1136 |
T1701 |
T1700 |
arg2Of |
thalamus,in |
| R1137 |
T1701 |
T1702 |
arg1Of |
thalamus,following |
| R1138 |
T1705 |
T1702 |
arg2Of |
seizure,following |
| R1139 |
T1705 |
T1703 |
arg1Of |
seizure,kainic |
| R1140 |
T1705 |
T1704 |
arg1Of |
seizure,acid-induced |
| R1141 |
T1707 |
T1706 |
arg2Of |
cytokines,Among |
| R1142 |
T1711 |
T1709 |
arg1Of |
factor-α,tumor |
| R1143 |
T1711 |
T1710 |
arg1Of |
factor-α,necrosis |
| R1144 |
T1711 |
T1712 |
arg1Of |
factor-α,( |
| R1145 |
T1711 |
T1715 |
arg1Of |
factor-α,is |
| R1146 |
T1713 |
T1712 |
arg2Of |
TNF-α,( |
| R1147 |
T1714 |
T1712 |
arg3Of |
),( |
| R1148 |
T1715 |
T1706 |
arg1Of |
is,Among |
| R1149 |
T1715 |
T1708 |
arg1Of |
is,"," |
| R1150 |
T1719 |
T1715 |
arg2Of |
protein,is |
| R1151 |
T1719 |
T1716 |
arg1Of |
protein,a |
| R1152 |
T1719 |
T1717 |
arg1Of |
protein,17 |
| R1153 |
T1719 |
T1718 |
arg1Of |
protein,kDa |
| R1154 |
T1719 |
T1720 |
arg1Of |
protein,that |
| R1155 |
T1719 |
T1721 |
arg1Of |
protein,is |
| R1156 |
T1719 |
T1722 |
arg2Of |
protein,produced |
| R1157 |
T1722 |
T1721 |
arg2Of |
produced,is |
| R1158 |
T1722 |
T1723 |
arg1Of |
produced,mainly |
| R1159 |
T1722 |
T1730 |
arg1Of |
produced,in |
| R1160 |
T1726 |
T1725 |
arg2Of |
macrophages,activated |
| R1161 |
T1726 |
T1727 |
arg1Of |
macrophages,and |
| R1162 |
T1727 |
T1722 |
arg1Of |
and,produced |
| R1163 |
T1727 |
T1724 |
arg2Of |
and,by |
| R1164 |
T1729 |
T1727 |
arg2Of |
cells,and |
| R1165 |
T1729 |
T1728 |
arg1Of |
cells,T |
| R1166 |
T1733 |
T1730 |
arg2Of |
system,in |
| R1167 |
T1733 |
T1731 |
arg1Of |
system,the |
| R1168 |
T1733 |
T1732 |
arg1Of |
system,immune |
| R1169 |
T1734 |
T1735 |
arg1Of |
TNF-α,is |
| R1170 |
T1734 |
T1736 |
arg2Of |
TNF-α,expressed |
| R1171 |
T1734 |
T1744 |
arg1Of |
TNF-α,is |
| R1172 |
T1734 |
T1746 |
arg2Of |
TNF-α,upregulated |
| R1173 |
T1736 |
T1735 |
arg2Of |
expressed,is |
| R1174 |
T1736 |
T1737 |
arg1Of |
expressed,at |
| R1175 |
T1736 |
T1740 |
arg1Of |
expressed,in |
| R1176 |
T1736 |
T1743 |
arg1Of |
expressed,and |
| R1177 |
T1739 |
T1737 |
arg2Of |
levels,at |
| R1178 |
T1739 |
T1738 |
arg1Of |
levels,low |
| R1179 |
T1742 |
T1740 |
arg2Of |
brain,in |
| R1180 |
T1742 |
T1741 |
arg1Of |
brain,normal |
| R1181 |
T1746 |
T1743 |
arg2Of |
upregulated,and |
| R1182 |
T1746 |
T1744 |
arg2Of |
upregulated,is |
| R1183 |
T1746 |
T1745 |
arg1Of |
upregulated,rapidly |
| R1184 |
T1746 |
T1747 |
arg1Of |
upregulated,in |
| R1185 |
T1748 |
T1749 |
arg1Of |
glia,"," |
| R1186 |
T1749 |
T1751 |
arg1Of |
",",and |
| R1187 |
T1750 |
T1749 |
arg2Of |
neurons,"," |
| R1188 |
T1751 |
T1747 |
arg2Of |
and,in |
| R1189 |
T1751 |
T1754 |
arg1Of |
and,in |
| R1190 |
T1753 |
T1751 |
arg2Of |
cells,and |
| R1191 |
T1753 |
T1752 |
arg1Of |
cells,endothelial |
| R1192 |
T1757 |
T1754 |
arg2Of |
conditions,in |
| R1193 |
T1757 |
T1755 |
arg1Of |
conditions,various |
| R1194 |
T1757 |
T1756 |
arg1Of |
conditions,pathophysiological |
| R1195 |
T1757 |
T1758 |
arg1Of |
conditions,"," |
| R1196 |
T1757 |
T1759 |
arg1Of |
conditions,including |
| R1197 |
T1760 |
T1759 |
arg2Of |
SE,including |
| R1198 |
T1760 |
T1761 |
arg1Of |
SE,[ |
| R1199 |
T1762 |
T1761 |
arg2Of |
"17,18",[ |
| R1200 |
T1763 |
T1761 |
arg3Of |
],[ |
| R1201 |
T1764 |
T1765 |
arg1Of |
TNF-α,shows |
| R1202 |
T1765 |
T1768 |
arg1Of |
shows,on |
| R1203 |
T1765 |
T1771 |
arg1Of |
shows,depending |
| R1204 |
T1765 |
T1813 |
arg1Of |
shows,[ |
| R1205 |
T1767 |
T1765 |
arg2Of |
effects,shows |
| R1206 |
T1767 |
T1766 |
arg1Of |
effects,various |
| R1207 |
T1770 |
T1768 |
arg2Of |
function,on |
| R1208 |
T1770 |
T1769 |
arg1Of |
function,brain |
| R1209 |
T1772 |
T1771 |
arg2Of |
on,depending |
| R1210 |
T1776 |
T1773 |
arg1Of |
concentration,its |
| R1211 |
T1776 |
T1774 |
arg1Of |
concentration,local |
| R1212 |
T1776 |
T1775 |
arg1Of |
concentration,tissue |
| R1213 |
T1776 |
T1777 |
arg1Of |
concentration,"," |
| R1214 |
T1776 |
T1784 |
arg1Of |
concentration,and |
| R1215 |
T1779 |
T1777 |
arg2Of |
type,"," |
| R1216 |
T1779 |
T1778 |
arg1Of |
type,the |
| R1217 |
T1779 |
T1780 |
arg1Of |
type,of |
| R1218 |
T1782 |
T1780 |
arg2Of |
cells,of |
| R1219 |
T1782 |
T1781 |
arg1Of |
cells,target |
| R1220 |
T1784 |
T1772 |
arg2Of |
and,on |
| R1221 |
T1784 |
T1783 |
arg1Of |
and,"," |
| R1222 |
T1784 |
T1790 |
arg1Of |
and,: |
| R1223 |
T1789 |
T1784 |
arg2Of |
subtype,and |
| R1224 |
T1789 |
T1785 |
arg1Of |
subtype,especially |
| R1225 |
T1789 |
T1786 |
arg1Of |
subtype,the |
| R1226 |
T1789 |
T1787 |
arg1Of |
subtype,specific |
| R1227 |
T1789 |
T1788 |
arg1Of |
subtype,receptor |
| R1228 |
T1793 |
T1791 |
arg1Of |
I,TNF |
| R1229 |
T1793 |
T1792 |
arg1Of |
I,receptor |
| R1230 |
T1793 |
T1795 |
arg1Of |
I,or |
| R1231 |
T1795 |
T1794 |
arg1Of |
or,"," |
| R1232 |
T1795 |
T1807 |
arg1Of |
or,or |
| R1233 |
T1797 |
T1796 |
arg1Of |
receptor,p55 |
| R1234 |
T1797 |
T1798 |
arg1Of |
receptor,( |
| R1235 |
T1797 |
T1802 |
arg1Of |
receptor,and |
| R1236 |
T1799 |
T1798 |
arg2Of |
TNFp55R,( |
| R1237 |
T1800 |
T1798 |
arg3Of |
),( |
| R1238 |
T1802 |
T1795 |
arg2Of |
and,or |
| R1239 |
T1802 |
T1801 |
arg1Of |
and,; |
| R1240 |
T1804 |
T1802 |
arg2Of |
receptor,and |
| R1241 |
T1804 |
T1803 |
arg1Of |
receptor,TNF |
| R1242 |
T1804 |
T1805 |
arg1Of |
receptor,II |
| R1243 |
T1807 |
T1790 |
arg2Of |
or,: |
| R1244 |
T1807 |
T1806 |
arg1Of |
or,"," |
| R1245 |
T1809 |
T1807 |
arg2Of |
receptor,or |
| R1246 |
T1809 |
T1808 |
arg1Of |
receptor,p75 |
| R1247 |
T1809 |
T1810 |
arg1Of |
receptor,( |
| R1248 |
T1811 |
T1810 |
arg2Of |
TNFp75R,( |
| R1249 |
T1812 |
T1810 |
arg3Of |
),( |
| R1250 |
T1814 |
T1813 |
arg2Of |
19,[ |
| R1251 |
T1815 |
T1813 |
arg3Of |
],[ |
| R1252 |
T1818 |
T1819 |
arg1Of |
TNF-α,induces |
| R1253 |
T1819 |
T1816 |
arg1Of |
induces,Furthermore |
| R1254 |
T1819 |
T1817 |
arg1Of |
induces,"," |
| R1255 |
T1822 |
T1819 |
arg2Of |
protein-2,induces |
| R1256 |
T1822 |
T1820 |
arg1Of |
protein-2,macrophage |
| R1257 |
T1822 |
T1821 |
arg1Of |
protein-2,inflammatory |
| R1258 |
T1822 |
T1823 |
arg1Of |
protein-2,( |
| R1259 |
T1822 |
T1826 |
arg1Of |
protein-2,that |
| R1260 |
T1822 |
T1827 |
arg1Of |
protein-2,recruits |
| R1261 |
T1824 |
T1823 |
arg2Of |
MIP-2,( |
| R1262 |
T1825 |
T1823 |
arg3Of |
),( |
| R1263 |
T1827 |
T1829 |
arg1Of |
recruits,under |
| R1264 |
T1828 |
T1827 |
arg2Of |
neutrophils,recruits |
| R1265 |
T1831 |
T1829 |
arg2Of |
conditions,under |
| R1266 |
T1831 |
T1830 |
arg1Of |
conditions,pathological |
| R1267 |
T1831 |
T1832 |
arg1Of |
conditions,"," |
| R1268 |
T1831 |
T1833 |
arg1Of |
conditions,including |
| R1269 |
T1834 |
T1833 |
arg2Of |
SE,including |
| R1270 |
T1834 |
T1835 |
arg1Of |
SE,[ |
| R1271 |
T1836 |
T1835 |
arg2Of |
"14,20",[ |
| R1272 |
T1837 |
T1835 |
arg3Of |
],[ |
| R1273 |
T1838 |
T1839 |
arg1Of |
Neurons,"," |
| R1274 |
T1839 |
T1842 |
arg1Of |
",",and |
| R1275 |
T1840 |
T1839 |
arg2Of |
microglia,"," |
| R1276 |
T1842 |
T1841 |
arg1Of |
and,"," |
| R1277 |
T1842 |
T1844 |
arg1Of |
and,produce |
| R1278 |
T1842 |
T1847 |
arg1Of |
and,incubated |
| R1279 |
T1843 |
T1842 |
arg2Of |
astrocytes,and |
| R1280 |
T1844 |
T1846 |
arg1Of |
produce,when |
| R1281 |
T1845 |
T1844 |
arg2Of |
MIP-2,produce |
| R1282 |
T1847 |
T1846 |
arg2Of |
incubated,when |
| R1283 |
T1847 |
T1848 |
arg1Of |
incubated,with |
| R1284 |
T1847 |
T1860 |
arg1Of |
incubated,after |
| R1285 |
T1848 |
T1859 |
arg1Of |
with,or |
| R1286 |
T1850 |
T1848 |
arg2Of |
cytokines,with |
| R1287 |
T1850 |
T1849 |
arg1Of |
cytokines,pro-inflammatory |
| R1288 |
T1850 |
T1852 |
arg1Of |
cytokines,as |
| R1289 |
T1852 |
T1851 |
arg1Of |
as,such |
| R1290 |
T1853 |
T1854 |
arg1Of |
TNF-α,and/or |
| R1291 |
T1854 |
T1852 |
arg2Of |
and/or,as |
| R1292 |
T1854 |
T1856 |
arg1Of |
and/or,( |
| R1293 |
T1855 |
T1854 |
arg2Of |
interleukin-1β,and/or |
| R1294 |
T1857 |
T1856 |
arg2Of |
IL-1β,( |
| R1295 |
T1858 |
T1856 |
arg3Of |
),( |
| R1296 |
T1860 |
T1859 |
arg2Of |
after,or |
| R1297 |
T1861 |
T1860 |
arg2Of |
injury,after |
| R1298 |
T1861 |
T1862 |
arg1Of |
injury,[ |
| R1299 |
T1863 |
T1862 |
arg2Of |
21-23,[ |
| R1300 |
T1864 |
T1862 |
arg3Of |
],[ |
| R1301 |
T1867 |
T1868 |
arg1Of |
we,have |
| R1302 |
T1867 |
T1870 |
arg1Of |
we,reported |
| R1303 |
T1870 |
T1865 |
arg1Of |
reported,Indeed |
| R1304 |
T1870 |
T1866 |
arg1Of |
reported,"," |
| R1305 |
T1870 |
T1868 |
arg2Of |
reported,have |
| R1306 |
T1870 |
T1869 |
arg1Of |
reported,recently |
| R1307 |
T1874 |
T1872 |
arg1Of |
expression,SE-mediated |
| R1308 |
T1874 |
T1873 |
arg1Of |
expression,MIP-2 |
| R1309 |
T1874 |
T1875 |
arg1Of |
expression,is |
| R1310 |
T1874 |
T1876 |
arg1Of |
expression,relevant |
| R1311 |
T1875 |
T1870 |
arg2Of |
is,reported |
| R1312 |
T1875 |
T1871 |
arg1Of |
is,that |
| R1313 |
T1875 |
T1886 |
arg1Of |
is,[ |
| R1314 |
T1876 |
T1875 |
arg2Of |
relevant,is |
| R1315 |
T1876 |
T1877 |
arg1Of |
relevant,to |
| R1316 |
T1879 |
T1877 |
arg2Of |
infiltrations,to |
| R1317 |
T1879 |
T1878 |
arg1Of |
infiltrations,leukocyte |
| R1318 |
T1879 |
T1880 |
arg1Of |
infiltrations,following |
| R1319 |
T1880 |
T1882 |
arg1Of |
following,in |
| R1320 |
T1881 |
T1880 |
arg2Of |
SE,following |
| R1321 |
T1885 |
T1882 |
arg2Of |
manner,in |
| R1322 |
T1885 |
T1883 |
arg1Of |
manner,an |
| R1323 |
T1885 |
T1884 |
arg1Of |
manner,IL-1β-independent |
| R1324 |
T1887 |
T1886 |
arg2Of |
20,[ |
| R1325 |
T1888 |
T1886 |
arg3Of |
],[ |
| R1326 |
T1892 |
T1891 |
arg1Of |
relationship,the |
| R1327 |
T1892 |
T1893 |
arg1Of |
relationship,between |
| R1328 |
T1892 |
T1909 |
arg1Of |
relationship,has |
| R1329 |
T1892 |
T1911 |
arg1Of |
relationship,been |
| R1330 |
T1892 |
T1913 |
arg2Of |
relationship,clarified |
| R1331 |
T1896 |
T1895 |
arg1Of |
system,TNF-α |
| R1332 |
T1896 |
T1897 |
arg1Of |
system,and |
| R1333 |
T1897 |
T1893 |
arg2Of |
and,between |
| R1334 |
T1897 |
T1894 |
arg1Of |
and,the |
| R1335 |
T1897 |
T1901 |
arg1Of |
and,during |
| R1336 |
T1900 |
T1897 |
arg2Of |
infiltration,and |
| R1337 |
T1900 |
T1898 |
arg1Of |
infiltration,BBB |
| R1338 |
T1900 |
T1899 |
arg1Of |
infiltration,disruption/neutrophil |
| R1339 |
T1904 |
T1901 |
arg2Of |
formation,during |
| R1340 |
T1904 |
T1902 |
arg1Of |
formation,vasogenic |
| R1341 |
T1904 |
T1903 |
arg1Of |
formation,edema |
| R1342 |
T1904 |
T1905 |
arg2Of |
formation,induced |
| R1343 |
T1908 |
T1905 |
arg1Of |
insults,induced |
| R1344 |
T1908 |
T1906 |
arg2Of |
insults,by |
| R1345 |
T1908 |
T1907 |
arg1Of |
insults,epileptogenic |
| R1346 |
T1913 |
T1889 |
arg1Of |
clarified,However |
| R1347 |
T1913 |
T1890 |
arg1Of |
clarified,"," |
| R1348 |
T1913 |
T1909 |
arg2Of |
clarified,has |
| R1349 |
T1913 |
T1910 |
arg1Of |
clarified,not |
| R1350 |
T1913 |
T1911 |
arg2Of |
clarified,been |
| R1351 |
T1913 |
T1912 |
arg1Of |
clarified,fully |
| R1352 |
T1919 |
T1916 |
arg2Of |
study,in |
| R1353 |
T1919 |
T1917 |
arg1Of |
study,the |
| R1354 |
T1919 |
T1918 |
arg1Of |
study,present |
| R1355 |
T1921 |
T1922 |
arg1Of |
we,investigated |
| R1356 |
T1922 |
T1914 |
arg1Of |
investigated,Therefore |
| R1357 |
T1922 |
T1915 |
arg1Of |
investigated,"," |
| R1358 |
T1922 |
T1916 |
arg1Of |
investigated,in |
| R1359 |
T1922 |
T1920 |
arg1Of |
investigated,"," |
| R1360 |
T1924 |
T1922 |
arg2Of |
roles,investigated |
| R1361 |
T1924 |
T1923 |
arg1Of |
roles,the |
| R1362 |
T1924 |
T1925 |
arg1Of |
roles,of |
| R1363 |
T1924 |
T1927 |
arg1Of |
roles,in |
| R1364 |
T1924 |
T1934 |
arg1Of |
roles,in |
| R1365 |
T1926 |
T1925 |
arg2Of |
TNF-α,of |
| R1366 |
T1929 |
T1928 |
arg1Of |
edema,vasogenic |
| R1367 |
T1929 |
T1930 |
arg1Of |
edema,and |
| R1368 |
T1930 |
T1927 |
arg2Of |
and,in |
| R1369 |
T1933 |
T1930 |
arg2Of |
events,and |
| R1370 |
T1933 |
T1931 |
arg1Of |
events,its |
| R1371 |
T1933 |
T1932 |
arg1Of |
events,related |
| R1372 |
T1937 |
T1934 |
arg2Of |
models,in |
| R1373 |
T1937 |
T1935 |
arg1Of |
models,rat |
| R1374 |
T1937 |
T1936 |
arg1Of |
models,epilepsy |
| R1375 |
T1937 |
T1938 |
arg2Of |
models,provoked |
| R1376 |
T1941 |
T1938 |
arg1Of |
SE,provoked |
| R1377 |
T1941 |
T1939 |
arg2Of |
SE,by |
| R1378 |
T1941 |
T1940 |
arg1Of |
SE,pilocarpine-induced |
| R711 |
T1272 |
T1271 |
arg1Of |
epilepticus,Status |
| R712 |
T1272 |
T1273 |
arg1Of |
epilepticus,( |
| R713 |
T1272 |
T1276 |
arg1Of |
epilepticus,is |
| R714 |
T1274 |
T1273 |
arg2Of |
SE,( |
| R715 |
T1275 |
T1273 |
arg3Of |
),( |
| R716 |
T1279 |
T1276 |
arg2Of |
emergency,is |
| R717 |
T1279 |
T1277 |
arg1Of |
emergency,a |
| R718 |
T1279 |
T1278 |
arg1Of |
emergency,medical |
| R719 |
T1279 |
T1280 |
arg1Of |
emergency,with |
| R720 |
T1282 |
T1280 |
arg2Of |
mortality,with |
| R721 |
T1282 |
T1281 |
arg1Of |
mortality,significant |
| R722 |
T1282 |
T1283 |
arg1Of |
mortality,[ |
| R723 |
T1284 |
T1283 |
arg2Of |
1,[ |
| R724 |
T1285 |
T1283 |
arg3Of |
],[ |
| R725 |
T1286 |
T1287 |
arg1Of |
SE,has |
| R726 |
T1286 |
T1288 |
arg1Of |
SE,been |
| R727 |
T1286 |
T1289 |
arg2Of |
SE,defined |
| R728 |
T1289 |
T1287 |
arg2Of |
defined,has |
| R729 |
T1289 |
T1288 |
arg2Of |
defined,been |
| R730 |
T1289 |
T1290 |
arg1Of |
defined,as |
| R731 |
T1293 |
T1290 |
arg2Of |
activity,as |
| R732 |
T1293 |
T1291 |
arg1Of |
activity,continuous |
| R733 |
T1293 |
T1292 |
arg1Of |
activity,seizure |
| R734 |
T1293 |
T1294 |
arg1Of |
activity,"," |
| R735 |
T1293 |
T1295 |
arg1Of |
activity,which |
| R736 |
T1293 |
T1296 |
arg1Of |
activity,causes |
| R737 |
T1299 |
T1297 |
arg1Of |
death,neuronal |
| R738 |
T1299 |
T1298 |
arg1Of |
death,cell |
| R739 |
T1299 |
T1300 |
arg1Of |
death,"," |
| R740 |
T1300 |
T1302 |
arg1Of |
",",and |
| R741 |
T1301 |
T1300 |
arg2Of |
epileptogenesis,"," |
| R742 |
T1302 |
T1296 |
arg2Of |
and,causes |
| R743 |
T1304 |
T1302 |
arg2Of |
impairment,and |
| R744 |
T1304 |
T1303 |
arg1Of |
impairment,learning |
| R745 |
T1304 |
T1305 |
arg1Of |
impairment,[ |
| R746 |
T1306 |
T1305 |
arg2Of |
"2,3",[ |
| R747 |
T1307 |
T1305 |
arg3Of |
],[ |
| R748 |
T1310 |
T1308 |
arg1Of |
regions,Some |
| R749 |
T1310 |
T1309 |
arg1Of |
regions,brain |
| R750 |
T1310 |
T1311 |
arg1Of |
regions,vulnerable |
| R751 |
T1310 |
T1314 |
arg1Of |
regions,play |
| R752 |
T1311 |
T1312 |
arg1Of |
vulnerable,to |
| R753 |
T1313 |
T1312 |
arg2Of |
SE,to |
| R754 |
T1314 |
T1317 |
arg1Of |
play,in |
| R755 |
T1316 |
T1314 |
arg2Of |
role,play |
| R756 |
T1316 |
T1315 |
arg1Of |
role,a |
| R757 |
T1319 |
T1320 |
arg1Of |
generation,and |
| R758 |
T1320 |
T1317 |
arg2Of |
and,in |
| R759 |
T1320 |
T1318 |
arg1Of |
and,the |
| R760 |
T1320 |
T1322 |
arg1Of |
and,of |
| R761 |
T1321 |
T1320 |
arg2Of |
propagation,and |
| R762 |
T1324 |
T1322 |
arg2Of |
activity,of |
| R763 |
T1324 |
T1323 |
arg1Of |
activity,paroxysmal |
| R764 |
T1324 |
T1325 |
arg1Of |
activity,in |
| R765 |
T1328 |
T1325 |
arg2Of |
models,in |
| R766 |
T1328 |
T1326 |
arg1Of |
models,experimental |
| R767 |
T1328 |
T1327 |
arg1Of |
models,epilepsy |
| R768 |
T1331 |
T1329 |
arg1Of |
cortex,The |
| R769 |
T1331 |
T1330 |
arg1Of |
cortex,piriform |
| R770 |
T1331 |
T1332 |
arg1Of |
cortex,( |
| R771 |
T1331 |
T1335 |
arg1Of |
cortex,is |
| R772 |
T1333 |
T1332 |
arg2Of |
PC,( |
| R773 |
T1334 |
T1332 |
arg3Of |
),( |
| R774 |
T1336 |
T1335 |
arg2Of |
one,is |
| R775 |
T1336 |
T1337 |
arg1Of |
one,of |
| R776 |
T1336 |
T1343 |
arg1Of |
one,to |
| R777 |
T1340 |
T1339 |
arg1Of |
susceptible,most |
| R778 |
T1342 |
T1337 |
arg2Of |
regions,of |
| R779 |
T1342 |
T1338 |
arg1Of |
regions,the |
| R780 |
T1342 |
T1340 |
arg1Of |
regions,susceptible |
| R781 |
T1342 |
T1341 |
arg1Of |
regions,brain |
| R782 |
T1345 |
T1344 |
arg1Of |
damage,seizure-induced |
| R783 |
T1345 |
T1346 |
arg1Of |
damage,in |
| R784 |
T1345 |
T1349 |
arg1Of |
damage,"," |
| R785 |
T1348 |
T1346 |
arg2Of |
kainate,in |
| R786 |
T1348 |
T1347 |
arg1Of |
kainate,the |
| R787 |
T1349 |
T1351 |
arg1Of |
",",and |
| R788 |
T1350 |
T1349 |
arg2Of |
pilocarpine,"," |
| R789 |
T1351 |
T1343 |
arg2Of |
and,to |
| R790 |
T1353 |
T1351 |
arg2Of |
models,and |
| R791 |
T1353 |
T1352 |
arg1Of |
models,other |
| R792 |
T1353 |
T1354 |
arg1Of |
models,of |
| R793 |
T1357 |
T1354 |
arg2Of |
epilepsy,of |
| R794 |
T1357 |
T1355 |
arg1Of |
epilepsy,temporal |
| R795 |
T1357 |
T1356 |
arg1Of |
epilepsy,lobe |
| R796 |
T1357 |
T1358 |
arg1Of |
epilepsy,( |
| R797 |
T1357 |
T1361 |
arg1Of |
epilepsy,[ |
| R798 |
T1359 |
T1358 |
arg2Of |
TLE,( |
| R799 |
T1360 |
T1358 |
arg3Of |
),( |
| R800 |
T1362 |
T1361 |
arg2Of |
4-6,[ |
| R801 |
T1363 |
T1361 |
arg3Of |
],[ |
| R802 |
T1364 |
T1365 |
arg1Of |
Pilocarpine,"," |
| R803 |
T1364 |
T1370 |
arg1Of |
Pilocarpine,induces |
| R804 |
T1368 |
T1365 |
arg2Of |
agonist,"," |
| R805 |
T1368 |
T1366 |
arg1Of |
agonist,a |
| R806 |
T1368 |
T1367 |
arg1Of |
agonist,cholinergic |
| R807 |
T1370 |
T1369 |
arg1Of |
induces,"," |
| R808 |
T1370 |
T1372 |
arg1Of |
induces,in |
| R809 |
T1371 |
T1370 |
arg2Of |
SE,induces |
| R810 |
T1373 |
T1372 |
arg2Of |
rodents,in |
| R811 |
T1376 |
T1374 |
arg1Of |
SE,This |
| R812 |
T1376 |
T1375 |
arg1Of |
SE,pilocarpine-induced |
| R813 |
T1376 |
T1377 |
arg1Of |
SE,"," |
| R814 |
T1376 |
T1378 |
arg1Of |
SE,similar |
| R815 |
T1376 |
T1383 |
arg1Of |
SE,shows |
| R816 |
T1378 |
T1379 |
arg1Of |
similar,to |
| R817 |
T1381 |
T1379 |
arg2Of |
TLE,to |
| R818 |
T1381 |
T1380 |
arg1Of |
TLE,human |
| R819 |
T1383 |
T1382 |
arg1Of |
shows,"," |
| R820 |
T1386 |
T1383 |
arg2Of |
loss,shows |
| R821 |
T1386 |
T1384 |
arg1Of |
loss,massive |
| R822 |
T1386 |
T1385 |
arg1Of |
loss,neuronal |
| R823 |
T1386 |
T1387 |
arg1Of |
loss,in |
| R824 |
T1389 |
T1387 |
arg2Of |
hippocampus,in |
| R825 |
T1389 |
T1388 |
arg1Of |
hippocampus,the |
| R826 |
T1389 |
T1390 |
arg2Of |
hippocampus,followed |
| R827 |
T1393 |
T1390 |
arg1Of |
proliferation,followed |
| R828 |
T1393 |
T1391 |
arg2Of |
proliferation,by |
| R829 |
T1393 |
T1392 |
arg1Of |
proliferation,glial |
| R830 |
T1396 |
T1394 |
arg1Of |
damage,This |
| R831 |
T1396 |
T1395 |
arg1Of |
damage,neuronal |
| R832 |
T1396 |
T1397 |
arg1Of |
damage,in |
| R833 |
T1396 |
T1401 |
arg1Of |
damage,is |
| R834 |
T1396 |
T1403 |
arg1Of |
damage,restricted |
| R835 |
T1396 |
T1410 |
arg1Of |
damage,extends |
| R836 |
T1400 |
T1397 |
arg2Of |
model,in |
| R837 |
T1400 |
T1398 |
arg1Of |
model,the |
| R838 |
T1400 |
T1399 |
arg1Of |
model,pilocarpine |
| R839 |
T1401 |
T1402 |
arg1Of |
is,not |
| R840 |
T1401 |
T1408 |
arg1Of |
is,but |
| R841 |
T1403 |
T1401 |
arg2Of |
restricted,is |
| R842 |
T1403 |
T1404 |
arg1Of |
restricted,to |
| R843 |
T1406 |
T1404 |
arg2Of |
hippocampus,to |
| R844 |
T1406 |
T1405 |
arg1Of |
hippocampus,the |
| R845 |
T1408 |
T1407 |
arg1Of |
but,"," |
| R846 |
T1410 |
T1408 |
arg2Of |
extends,but |
| R847 |
T1410 |
T1409 |
arg1Of |
extends,often |
| R848 |
T1410 |
T1411 |
arg1Of |
extends,to |
| R849 |
T1414 |
T1411 |
arg2Of |
structures,to |
| R850 |
T1414 |
T1412 |
arg1Of |
structures,extrahippocampal |
| R851 |
T1414 |
T1413 |
arg1Of |
structures,limbic |
| R852 |
T1418 |
T1417 |
arg1Of |
SE,pilocarpine-induced |
| R853 |
T1418 |
T1419 |
arg1Of |
SE,results |
| R854 |
T1419 |
T1415 |
arg1Of |
results,Indeed |
| R855 |
T1419 |
T1416 |
arg1Of |
results,"," |
| R856 |
T1419 |
T1420 |
arg1Of |
results,in |
| R857 |
T1419 |
T1432 |
arg1Of |
results,[ |
| R858 |
T1423 |
T1420 |
arg2Of |
damages,in |
| R859 |
T1423 |
T1421 |
arg1Of |
damages,acute |
| R860 |
T1423 |
T1422 |
arg1Of |
damages,neuronal |
| R861 |
T1423 |
T1424 |
arg1Of |
damages,within |
| R862 |
T1426 |
T1427 |
arg1Of |
II,and |
| R863 |
T1427 |
T1424 |
arg2Of |
and,within |
| R864 |
T1427 |
T1425 |
arg1Of |
and,layers |
| R865 |
T1427 |
T1429 |
arg1Of |
and,of |
| R866 |
T1428 |
T1427 |
arg2Of |
III,and |
| R867 |
T1431 |
T1429 |
arg2Of |
PC,of |
| R868 |
T1431 |
T1430 |
arg1Of |
PC,the |
| R869 |
T1433 |
T1432 |
arg2Of |
"5,6",[ |
| R870 |
T1434 |
T1432 |
arg3Of |
],[ |
| R871 |
T1435 |
T1437 |
arg1Of |
SE,induces |
| R872 |
T1437 |
T1436 |
arg1Of |
induces,also |
| R873 |
T1437 |
T1441 |
arg1Of |
induces,in |
| R874 |
T1440 |
T1437 |
arg2Of |
edema,induces |
| R875 |
T1440 |
T1438 |
arg1Of |
edema,severe |
| R876 |
T1440 |
T1439 |
arg1Of |
edema,vasogenic |
| R877 |
T1443 |
T1441 |
arg2Of |
PC,in |
| R878 |
T1443 |
T1442 |
arg1Of |
PC,the |
| R879 |
T1443 |
T1444 |
arg2Of |
PC,accompanied |
| R880 |
T1446 |
T1447 |
arg1Of |
neuronal,and |
| R881 |
T1448 |
T1447 |
arg2Of |
astroglial,and |
| R882 |
T1449 |
T1444 |
arg1Of |
damages,accompanied |
| R883 |
T1449 |
T1445 |
arg2Of |
damages,by |
| R884 |
T1449 |
T1446 |
arg1Of |
damages,neuronal |
| R885 |
T1449 |
T1448 |
arg1Of |
damages,astroglial |
| R886 |
T1449 |
T1450 |
arg1Of |
damages,[ |
| R887 |
T1451 |
T1450 |
arg2Of |
5-8,[ |
| R888 |
T1452 |
T1450 |
arg3Of |
],[ |
| R889 |
T1455 |
T1453 |
arg1Of |
proceeds,Brain |
| R890 |
T1455 |
T1454 |
arg1Of |
proceeds,edema |
| R891 |
T1455 |
T1456 |
arg1Of |
proceeds,in |
| R892 |
T1455 |
T1459 |
arg1Of |
proceeds,"," |
| R893 |
T1458 |
T1456 |
arg2Of |
phases,in |
| R894 |
T1458 |
T1457 |
arg1Of |
phases,two |
| R895 |
T1463 |
T1460 |
arg1Of |
phase,early |
| R896 |
T1463 |
T1461 |
arg1Of |
phase,cytotoxic |
| R897 |
T1463 |
T1462 |
arg1Of |
phase,edema |
| R898 |
T1463 |
T1464 |
arg1Of |
phase,and |
| R899 |
T1464 |
T1459 |
arg2Of |
and,"," |
| R900 |
T1468 |
T1464 |
arg2Of |
phase,and |
| R901 |
T1468 |
T1465 |
arg1Of |
phase,late |
| R902 |
T1468 |
T1466 |
arg1Of |
phase,vasogenic |
| R903 |
T1468 |
T1467 |
arg1Of |
phase,edema |
| R904 |
T1472 |
T1469 |
arg1Of |
edema,Early |
| R905 |
T1472 |
T1470 |
arg1Of |
edema,cytotoxic |
| R906 |
T1472 |
T1471 |
arg1Of |
edema,osmotic |
| R907 |
T1472 |
T1473 |
arg1Of |
edema,is |
| R908 |
T1472 |
T1474 |
arg1Of |
edema,due |
| R909 |
T1474 |
T1473 |
arg2Of |
due,is |
| R910 |
T1474 |
T1475 |
arg1Of |
due,to |
| R911 |
T1477 |
T1475 |
arg2Of |
stimulation,to |
| R912 |
T1477 |
T1476 |
arg1Of |
stimulation,excess |
| R913 |
T1477 |
T1478 |
arg1Of |
stimulation,of |
| R914 |
T1477 |
T1481 |
arg1Of |
stimulation,during |
| R915 |
T1477 |
T1483 |
arg1Of |
stimulation,"," |
| R916 |
T1477 |
T1484 |
arg1Of |
stimulation,which |
| R917 |
T1477 |
T1485 |
arg1Of |
stimulation,increases |
| R918 |
T1480 |
T1478 |
arg2Of |
pathways,of |
| R919 |
T1480 |
T1479 |
arg1Of |
pathways,glutamatergic |
| R920 |
T1482 |
T1481 |
arg2Of |
SE,during |
| R921 |
T1487 |
T1488 |
arg1Of |
Na+,and |
| R922 |
T1489 |
T1488 |
arg2Of |
Ca2+,and |
| R923 |
T1490 |
T1485 |
arg2Of |
concentrations,increases |
| R924 |
T1490 |
T1486 |
arg1Of |
concentrations,intracellular |
| R925 |
T1490 |
T1487 |
arg1Of |
concentrations,Na+ |
| R926 |
T1490 |
T1489 |
arg1Of |
concentrations,Ca2+ |
| R927 |
T1493 |
T1491 |
arg1Of |
edema,The |
| R928 |
T1493 |
T1492 |
arg1Of |
edema,vasogenic |
| R929 |
T1493 |
T1494 |
arg1Of |
edema,results |
| R930 |
T1494 |
T1495 |
arg1Of |
results,from |
| R931 |
T1496 |
T1497 |
arg1Of |
dysfunction,of |
| R932 |
T1496 |
T1500 |
arg1Of |
dysfunction,and |
| R933 |
T1499 |
T1497 |
arg2Of |
cells,of |
| R934 |
T1499 |
T1498 |
arg1Of |
cells,endothelial |
| R935 |
T1500 |
T1495 |
arg2Of |
and,from |
| R936 |
T1503 |
T1500 |
arg2Of |
barrier,and |
| R937 |
T1503 |
T1501 |
arg1Of |
barrier,the |
| R938 |
T1503 |
T1502 |
arg1Of |
barrier,blood-brain |
| R939 |
T1503 |
T1504 |
arg1Of |
barrier,( |
| R940 |
T1505 |
T1504 |
arg2Of |
BBB,( |
| R941 |
T1506 |
T1504 |
arg3Of |
),( |
| R942 |
T1508 |
T1507 |
arg1Of |
studies,Many |
| R943 |
T1508 |
T1509 |
arg1Of |
studies,have |
| R944 |
T1508 |
T1510 |
arg1Of |
studies,reported |
| R945 |
T1510 |
T1509 |
arg2Of |
reported,have |
| R946 |
T1510 |
T1516 |
arg1Of |
reported,during |
| R947 |
T1512 |
T1510 |
arg2Of |
permeability,reported |
| R948 |
T1512 |
T1511 |
arg2Of |
permeability,increased |
| R949 |
T1512 |
T1513 |
arg1Of |
permeability,of |
| R950 |
T1515 |
T1513 |
arg2Of |
BBB,of |
| R951 |
T1515 |
T1514 |
arg1Of |
BBB,the |
| R952 |
T1518 |
T1516 |
arg2Of |
activity,during |
| R953 |
T1518 |
T1517 |
arg1Of |
activity,epileptic |
| R954 |
T1518 |
T1519 |
arg1Of |
activity,[ |
| R955 |
T1520 |
T1519 |
arg2Of |
9-13,[ |
| R956 |
T1521 |
T1519 |
arg3Of |
],[ |
| R957 |
T1523 |
T1524 |
arg1Of |
fast,and |
| R958 |
T1525 |
T1524 |
arg2Of |
significant,and |
| R959 |
T1526 |
T1522 |
arg1Of |
increase,A |
| R960 |
T1526 |
T1523 |
arg1Of |
increase,fast |
| R961 |
T1526 |
T1525 |
arg1Of |
increase,significant |
| R962 |
T1526 |
T1527 |
arg1Of |
increase,in |
| R963 |
T1526 |
T1531 |
arg1Of |
increase,"," |
| R964 |
T1526 |
T1533 |
arg2Of |
increase,shown |
| R965 |
T1526 |
T1539 |
arg1Of |
increase,induces |
| R966 |
T1530 |
T1527 |
arg2Of |
pressure,in |
| R967 |
T1530 |
T1528 |
arg1Of |
pressure,systemic |
| R968 |
T1530 |
T1529 |
arg1Of |
pressure,blood |
| R969 |
T1533 |
T1532 |
arg1Of |
shown,particularly |
| R970 |
T1533 |
T1534 |
arg1Of |
shown,during |
| R971 |
T1537 |
T1534 |
arg2Of |
seizures,during |
| R972 |
T1537 |
T1535 |
arg1Of |
seizures,tonic |
| R973 |
T1537 |
T1536 |
arg1Of |
seizures,epileptic |
| R974 |
T1539 |
T1538 |
arg1Of |
induces,"," |
| R975 |
T1542 |
T1540 |
arg1Of |
vasodilation,a |
| R976 |
T1542 |
T1541 |
arg1Of |
vasodilation,marked |
| R977 |
T1542 |
T1543 |
arg1Of |
vasodilation,of |
| R978 |
T1542 |
T1548 |
arg1Of |
vasodilation,and |
| R979 |
T1547 |
T1543 |
arg2Of |
arteries,of |
| R980 |
T1547 |
T1544 |
arg1Of |
arteries,the |
| R981 |
T1547 |
T1545 |
arg1Of |
arteries,large |
| R982 |
T1547 |
T1546 |
arg1Of |
arteries,cerebral |
| R983 |
T1548 |
T1539 |
arg2Of |
and,induces |
| R984 |
T1550 |
T1548 |
arg2Of |
increase,and |
| R985 |
T1550 |
T1549 |
arg1Of |
increase,an |
| R986 |
T1550 |
T1551 |
arg1Of |
increase,in |
| R987 |
T1550 |
T1554 |
arg1Of |
increase,in |
| R988 |
T1553 |
T1551 |
arg2Of |
pressure,in |
| R989 |
T1553 |
T1552 |
arg1Of |
pressure,blood |
| R990 |
T1555 |
T1556 |
arg1Of |
capillaries,"," |
| R991 |
T1556 |
T1560 |
arg1Of |
",",and |
| R992 |
T1558 |
T1556 |
arg2Of |
arteries,"," |
| R993 |
T1558 |
T1557 |
arg1Of |
arteries,small |
| R994 |
T1560 |
T1554 |
arg2Of |
and,in |
| R995 |
T1560 |
T1559 |
arg1Of |
and,"," |
| R996 |
T1561 |
T1560 |
arg2Of |
veins,and |
| R997 |
T1561 |
T1562 |
arg1Of |
veins,leading |
| R998 |
T1562 |
T1563 |
arg1Of |
leading,to |
| R999 |
T1564 |
T1563 |
arg2Of |
leakage,to |
