> top > projects > pmc-enju-pas > docs > PMC:2889865 > annotations
pmc-enju-pas Home  

PMC:2889865 JSONTXT 22 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T539 0-12 JJ denotes Differential
T540 13-21 NN denotes cytokine
T541 22-32 NN denotes regulation
T542 33-35 IN denotes by
T543 36-41 NN denotes NF-κB
T544 42-45 CC denotes and
T545 46-50 NN denotes AP-1
T546 51-53 IN denotes in
T547 54-60 NN denotes Jurkat
T548 61-68 NN denotes T-cells
T549 80-90 NN denotes Background
T550 91-100 NN denotes Activator
T551 101-108 NN denotes protein
T552 109-110 -LRB- denotes (
T553 110-112 NN denotes AP
T554 112-113 -RRB- denotes )
T555 113-115 CD denotes -1
T556 116-119 CC denotes and
T557 120-127 JJ denotes nuclear
T558 128-134 NN denotes factor
T559 135-136 -LRB- denotes (
T560 136-138 NN denotes NF
T561 138-139 -RRB- denotes )
T562 139-142 NN denotes -κB
T563 143-150 RB denotes largely
T564 151-158 VB denotes control
T565 159-165 NN denotes T-cell
T566 166-176 NN denotes activation
T567 176-177 -COMMA- denotes ,
T568 178-187 VB denotes following
T569 188-195 NN denotes binding
T570 196-198 IN denotes of
T571 199-206 JJ denotes foreign
T572 207-215 NN denotes antigens
T573 216-218 TO denotes to
T574 219-222 DT denotes the
T575 223-229 NN denotes T-cell
T576 230-238 NN denotes receptor
T577 239-246 VB denotes leading
T578 247-249 TO denotes to
T579 250-258 NN denotes cytokine
T580 259-268 NN denotes secretion
T581 270-278 JJ denotes Elevated
T582 279-285 NN denotes levels
T583 286-288 IN denotes of
T584 289-305 JJ denotes pro-inflammatory
T585 306-315 NN denotes cytokines
T586 316-319 CC denotes and
T587 320-330 NN denotes chemokines
T588 331-335 JJ denotes such
T589 336-338 IN denotes as
T590 339-342 NN denotes TNF
T591 342-343 -COMMA- denotes ,
T592 344-348 NN denotes IL-6
T593 349-352 CC denotes and
T594 353-358 NN denotes CXCL8
T595 359-362 VB denotes are
T596 363-373 VB denotes associated
T597 374-378 IN denotes with
T598 379-386 JJ denotes several
T599 387-392 JJ denotes human
T600 393-401 NN denotes diseases
T601 402-411 VB denotes including
T602 412-418 JJ denotes cystic
T603 419-427 NN denotes fibrosis
T604 427-428 -COMMA- denotes ,
T605 429-438 JJ denotes pulmonary
T606 439-447 NN denotes fibrosis
T607 448-451 CC denotes and
T608 452-456 NN denotes AIDS
T609 458-461 DT denotes The
T610 462-465 NN denotes aim
T611 466-468 IN denotes of
T612 469-473 DT denotes this
T613 474-479 NN denotes study
T614 480-483 VB denotes was
T615 484-486 TO denotes to
T616 487-498 VB denotes investigate
T617 499-502 DT denotes the
T618 503-507 NN denotes role
T619 508-510 IN denotes of
T620 511-514 DT denotes the
T621 515-528 NN denotes transcription
T622 529-536 NN denotes factors
T623 536-537 -COMMA- denotes ,
T624 538-542 NN denotes AP-1
T625 543-546 CC denotes and
T626 547-552 NN denotes NF-κB
T627 552-553 -COMMA- denotes ,
T628 554-556 IN denotes in
T629 557-561 NN denotes IL-6
T630 562-565 CC denotes and
T631 566-571 NN denotes CXCL8
T632 572-582 NN denotes regulation
T633 583-585 IN denotes in
T634 586-592 NN denotes Jurkat
T635 593-600 NN denotes T-cells
T636 603-610 NN denotes Results
T637 611-618 NN denotes Phorbol
T638 619-628 NN denotes myristate
T639 629-636 NN denotes acetate
T640 637-638 -LRB- denotes (
T641 638-641 NN denotes PMA
T642 641-642 -RRB- denotes )
T643 643-651 NN denotes exposure
T644 652-660 VB denotes resulted
T645 661-663 IN denotes in
T646 664-666 DT denotes an
T647 667-680 NN denotes up-regulation
T3418 670-680 NN denotes regulation
T648 681-683 IN denotes of
T3419 681-683 IN denotes of
T649 684-688 NN denotes AP-1
T3420 684-688 NN denotes AP-1
T650 689-692 CC denotes and
T3421 689-692 CC denotes and
T651 693-708 NN denotes down-regulation
T652 709-711 IN denotes of
T653 712-717 NN denotes NF-κB
T654 718-726 NN denotes activity
T655 726-727 -COMMA- denotes ,
T656 728-735 RB denotes however
T657 735-736 -COMMA- denotes ,
T658 737-745 NN denotes exposure
T659 746-748 TO denotes to
T660 749-753 NN denotes heat
T661 754-760 VB denotes killed
T662 761-762 -LRB- denotes (
T663 762-764 NN denotes HK
T664 764-765 -RRB- denotes )
T665 766-778 FW denotes Escherichia.
T666 779-783 FW denotes coli
T667 784-790 NN denotes MG1655
T668 791-799 VB denotes resulted
T669 800-802 IN denotes in
T670 803-804 DT denotes a
T671 805-819 JJ denotes dose-dependent
T672 820-828 NN denotes increase
T673 829-831 IN denotes in
T674 832-837 NN denotes NF-κB
T675 838-846 NN denotes activity
T676 847-854 IN denotes without
T677 855-864 VB denotes affecting
T678 865-869 NN denotes AP-1
T679 871-874 DT denotes The
T680 875-883 NN denotes cytokine
T681 884-891 NN denotes profile
T682 892-900 VB denotes revealed
T683 901-903 DT denotes an
T684 904-917 NN denotes up-regulation
T685 918-920 IN denotes of
T686 921-924 DT denotes the
T687 925-934 NN denotes chemokine
T688 935-940 NN denotes CXCL8
T689 941-944 CC denotes and
T690 945-948 DT denotes the
T691 949-965 JJ denotes pro-inflammatory
T692 966-975 NN denotes cytokines
T693 976-979 NN denotes TNF
T694 979-980 -COMMA- denotes ,
T695 981-985 NN denotes IL-2
T696 986-989 CC denotes and
T697 990-994 NN denotes IL-6
T698 995-1004 VB denotes following
T699 1005-1014 NN denotes treatment
T700 1015-1019 IN denotes with
T701 1020-1024 CC denotes both
T702 1025-1028 NN denotes PMA
T703 1029-1032 CC denotes and
T704 1033-1035 NN denotes HK
T705 1036-1038 FW denotes E.
T706 1039-1043 FW denotes coli
T707 1043-1044 -COMMA- denotes ,
T708 1045-1050 IN denotes while
T709 1051-1054 DT denotes the
T710 1055-1061 NN denotes levels
T711 1062-1064 IN denotes of
T712 1065-1068 DT denotes the
T713 1069-1086 JJ denotes anti-inflammatory
T714 1087-1095 NN denotes cytokine
T715 1096-1101 NN denotes IL-10
T716 1102-1106 VB denotes were
T717 1107-1110 RB denotes not
T718 1111-1119 VB denotes affected
T719 1120-1122 IN denotes by
T720 1123-1126 NN denotes PMA
T721 1127-1130 CC denotes but
T722 1131-1135 VB denotes were
T723 1136-1149 RB denotes significantly
T724 1150-1164 VB denotes down-regulated
T725 1165-1167 IN denotes by
T726 1168-1170 NNP denotes HK
T727 1171-1173 NNP denotes E.
T728 1174-1178 FW denotes coli
T729 1180-1184 NN denotes AP-1
T730 1185-1195 NN denotes activation
T731 1196-1199 VB denotes was
T732 1200-1213 RB denotes significantly
T733 1214-1223 VB denotes increased
T734 1224-1225 CD denotes 2
T735 1226-1227 NN denotes h
T736 1228-1233 IN denotes after
T737 1234-1237 NN denotes PMA
T738 1238-1246 NN denotes exposure
T739 1247-1250 CC denotes and
T740 1251-1260 VB denotes continued
T741 1261-1263 TO denotes to
T742 1264-1272 VB denotes increase
T743 1273-1283 RB denotes thereafter
T744 1285-1287 IN denotes In
T745 1288-1296 NN denotes contrast
T746 1296-1297 -COMMA- denotes ,
T747 1298-1303 NN denotes NF-κB
T748 1304-1313 VB denotes responded
T749 1314-1316 TO denotes to
T750 1317-1320 NN denotes PMA
T751 1321-1329 NN denotes exposure
T752 1330-1332 IN denotes by
T753 1333-1334 DT denotes a
T754 1335-1340 JJ denotes rapid
T755 1341-1354 NN denotes up-regulation
T756 1355-1363 VB denotes followed
T757 1364-1366 IN denotes by
T758 1367-1368 DT denotes a
T759 1369-1379 JJ denotes subsequent
T760 1380-1395 NN denotes down-regulation
T761 1397-1406 VB denotes Increased
T762 1407-1420 JJ denotes intracellular
T763 1421-1425 NN denotes Ca2+
T764 1426-1440 NN denotes concentrations
T765 1441-1450 VB denotes countered
T766 1451-1454 DT denotes the
T767 1455-1470 NN denotes down-regulation
T768 1471-1473 IN denotes of
T769 1474-1479 NN denotes NF-κB
T770 1480-1482 IN denotes by
T771 1483-1486 NN denotes PMA
T772 1486-1487 -COMMA- denotes ,
T773 1488-1493 IN denotes while
T774 1494-1501 JJ denotes similar
T775 1502-1511 NN denotes treatment
T776 1512-1516 IN denotes with
T777 1517-1524 NN denotes calcium
T778 1525-1534 NN denotes ionophore
T779 1535-1543 VB denotes resulted
T780 1544-1546 IN denotes in
T781 1547-1548 DT denotes a
T782 1549-1556 VB denotes reduced
T783 1557-1562 NN denotes NF-κB
T784 1563-1571 NN denotes activity
T785 1572-1581 VB denotes following
T786 1582-1591 NN denotes induction
T787 1592-1596 IN denotes with
T788 1597-1599 NN denotes HK
T789 1600-1602 FW denotes E.
T790 1603-1607 FW denotes coli
T791 1609-1611 IN denotes In
T792 1612-1617 NN denotes order
T793 1618-1620 TO denotes to
T794 1621-1628 JJ denotes further
T795 1629-1634 NN denotes study
T796 1635-1640 NN denotes NF-κB
T797 1641-1651 NN denotes activation
T798 1651-1652 -COMMA- denotes ,
T799 1653-1655 PRP denotes we
T800 1656-1666 VB denotes considered
T801 1667-1670 CD denotes two
T802 1671-1680 JJ denotes up-stream
T803 1681-1691 NN denotes signalling
T804 1692-1700 NN denotes proteins
T805 1700-1701 -COMMA- denotes ,
T806 1702-1705 NN denotes PKC
T807 1706-1709 CC denotes and
T808 1710-1715 NN denotes Bcl10
T809 1717-1735 NN denotes Phosphorylated-PKC
T810 1736-1742 NN denotes levels
T811 1743-1752 VB denotes increased
T812 1753-1755 IN denotes in
T813 1756-1764 NN denotes response
T814 1765-1767 TO denotes to
T815 1768-1771 NN denotes PMA
T816 1772-1775 CC denotes and
T817 1776-1778 NN denotes HK
T818 1779-1781 FW denotes E.
T819 1782-1786 FW denotes coli
T820 1786-1787 -COMMA- denotes ,
T821 1788-1793 IN denotes while
T822 1794-1799 NN denotes Bcl10
T823 1800-1806 NN denotes levels
T824 1807-1820 RB denotes significantly
T825 1821-1830 VB denotes decreased
T826 1831-1840 VB denotes following
T827 1841-1844 NN denotes PMA
T828 1845-1854 NN denotes treatment
T829 1856-1861 VB denotes Using
T830 1862-1864 DT denotes an
T831 1865-1870 NN denotes NF-κB
T832 1871-1881 NN denotes activation
T833 1882-1891 NN denotes inhibitor
T834 1891-1892 -COMMA- denotes ,
T835 1893-1895 PRP denotes we
T836 1896-1904 VB denotes observed
T837 1905-1913 JJ denotes complete
T838 1914-1924 NN denotes inhibition
T839 1925-1927 IN denotes of
T840 1928-1932 NN denotes IL-6
T841 1933-1943 NN denotes expression
T842 1944-1949 IN denotes while
T843 1950-1955 NN denotes CXCL8
T844 1956-1962 NN denotes levels
T845 1963-1967 RB denotes only
T846 1968-1977 VB denotes decreased
T847 1978-1980 IN denotes by
T848 1981-1983 CD denotes 40
T849 1983-1984 NN denotes %
T850 1985-1987 IN denotes at
T851 1988-1991 DT denotes the
T852 1992-1999 JJ denotes highest
T853 2000-2013 NN denotes concentration
T854 2015-2024 NN denotes Treatment
T855 2025-2027 IN denotes of
T856 2028-2034 NN denotes Jurkat
T857 2035-2042 NN denotes T-cells
T858 2043-2047 IN denotes with
T859 2048-2051 NN denotes PMA
T860 2052-2054 IN denotes in
T861 2055-2058 DT denotes the
T862 2059-2067 NN denotes presence
T863 2068-2070 IN denotes of
T864 2071-2084 NN denotes JNK-inhibitor
T865 2085-2095 VB denotes suppressed
T866 2096-2100 CC denotes both
T867 2101-2106 NN denotes CXCL8
T868 2107-2110 CC denotes and
T869 2111-2115 NN denotes IL-6
T870 2116-2121 IN denotes while
T871 2122-2135 NN denotes PKC-inhibitor
T872 2136-2145 RB denotes primarily
T873 2146-2155 VB denotes decreased
T874 2156-2161 NN denotes CXCL8
T875 2162-2172 NN denotes expression
T876 2175-2185 NN denotes Conclusion
T877 2186-2189 DT denotes The
T878 2190-2197 JJ denotes present
T879 2198-2203 NN denotes study
T880 2204-2209 VB denotes shows
T881 2210-2214 IN denotes that
T882 2215-2220 NN denotes NF-κB
T883 2221-2230 VB denotes regulated
T884 2231-2235 NN denotes IL-6
T885 2236-2239 CC denotes but
T886 2240-2243 RB denotes not
T887 2244-2249 NN denotes CXCL8
T888 2251-2255 DT denotes This
T889 2256-2263 JJ denotes complex
T890 2264-2274 NN denotes regulation
T891 2275-2277 IN denotes of
T892 2278-2283 NN denotes CXCL8
T893 2284-2292 VB denotes suggests
T894 2293-2297 IN denotes that
T895 2298-2303 EX denotes there
T896 2304-2306 VB denotes is
T897 2307-2308 DT denotes a
T898 2309-2313 NN denotes need
T899 2314-2316 TO denotes to
T900 2317-2324 RB denotes further
T901 2325-2333 VB denotes evaluate
T902 2334-2337 DT denotes the
T903 2338-2348 NN denotes signalling
T904 2349-2357 NN denotes pathways
T905 2358-2360 IN denotes in
T906 2361-2366 NN denotes order
T907 2367-2369 TO denotes to
T908 2370-2377 VB denotes develop
T909 2378-2381 JJ denotes new
T910 2382-2391 NN denotes treatment
T911 2392-2395 IN denotes for
T912 2396-2404 NN denotes diseases
T913 2405-2409 IN denotes with
T914 2410-2418 JJ denotes elevated
T915 2419-2424 NN denotes CXCL8
T916 2425-2431 NN denotes levels
T917 2431-2432 -COMMA- denotes ,
T918 2433-2437 JJ denotes such
T919 2438-2440 IN denotes as
T920 2441-2445 NN denotes AIDS
T921 2446-2449 CC denotes and
T922 2450-2460 JJ denotes autoimmune
T923 2461-2469 NN denotes diseases
T2024 2484-2493 NN denotes Cytokines
T2025 2494-2497 CC denotes and
T2026 2498-2508 NN denotes chemokines
T2027 2509-2512 VB denotes are
T2028 2513-2522 JJ denotes important
T2029 2523-2525 IN denotes in
T2030 2526-2532 JJ denotes immune
T2031 2533-2537 NN denotes cell
T2032 2538-2549 NN denotes recruitment
T2033 2550-2553 CC denotes and
T2034 2554-2556 IN denotes in
T2035 2557-2567 NN denotes regulation
T2036 2568-2570 IN denotes of
T2037 2571-2583 JJ denotes inflammatory
T2038 2584-2593 NN denotes responses
T2039 2594-2595 -LRB- denotes [
T2040 2595-2596 CD denotes 1
T2041 2596-2597 -RRB- denotes ]
T2042 2599-2606 NN denotes T-cells
T2043 2607-2614 VB denotes produce
T2044 2615-2616 DT denotes a
T2045 2617-2622 JJ denotes broad
T2046 2623-2628 NN denotes range
T2047 2629-2631 IN denotes of
T2048 2632-2644 JJ denotes inflammatory
T2049 2645-2654 NN denotes mediators
T2050 2654-2655 -COMMA- denotes ,
T2051 2656-2665 VB denotes including
T2052 2666-2670 NN denotes IL-2
T2053 2670-2671 -COMMA- denotes ,
T2054 2672-2676 NN denotes IL-6
T2055 2676-2677 -COMMA- denotes ,
T2056 2678-2681 NN denotes TNF
T2057 2682-2685 CC denotes and
T2058 2686-2691 NN denotes CXCL8
T2059 2691-2692 -COMMA- denotes ,
T2060 2693-2696 DT denotes all
T2061 2697-2699 IN denotes of
T2062 2700-2705 WDT denotes which
T2063 2706-2709 VB denotes are
T2064 2710-2719 JJ denotes important
T2065 2720-2722 IN denotes in
T2066 2723-2727 NN denotes cell
T2067 2728-2741 NN denotes proliferation
T2068 2741-2742 -COMMA- denotes ,
T2069 2743-2758 NN denotes differentiation
T2070 2758-2759 -COMMA- denotes ,
T2071 2760-2773 NN denotes communication
T2072 2774-2777 CC denotes and
T2073 2778-2788 NN denotes initiation
T2074 2789-2791 IN denotes of
T2075 2792-2804 JJ denotes inflammatory
T2076 2805-2814 NN denotes responses
T2077 2815-2816 -LRB- denotes [
T2078 2816-2817 CD denotes 2
T2079 2817-2818 -RRB- denotes ]
T2080 2820-2828 JJ denotes Elevated
T2081 2829-2835 NN denotes levels
T2082 2836-2838 IN denotes of
T2083 2839-2855 JJ denotes pro-inflammatory
T2084 2856-2865 NN denotes cytokines
T2085 2866-2869 CC denotes and
T2086 2870-2880 NN denotes chemokines
T2087 2880-2881 -COMMA- denotes ,
T2088 2882-2886 JJ denotes such
T2089 2887-2889 IN denotes as
T2090 2890-2893 NN denotes TNF
T2091 2893-2894 -COMMA- denotes ,
T2092 2895-2899 NN denotes IL-6
T2093 2900-2903 CC denotes and
T2094 2904-2909 NN denotes CXCL8
T2095 2909-2910 -COMMA- denotes ,
T2096 2911-2914 VB denotes are
T2097 2915-2925 VB denotes associated
T2098 2926-2930 IN denotes with
T2099 2931-2938 JJ denotes several
T2100 2939-2944 JJ denotes human
T2101 2945-2953 NN denotes diseases
T2102 2954-2963 VB denotes including
T2103 2964-2970 JJ denotes cystic
T2104 2971-2979 NN denotes fibrosis
T2105 2980-2981 -LRB- denotes [
T2106 2981-2984 CD denotes 3-5
T2107 2984-2985 -RRB- denotes ]
T2108 2985-2986 -COMMA- denotes ,
T2109 2987-2996 JJ denotes pulmonary
T2110 2997-3005 NN denotes fibrosis
T2111 3006-3007 -LRB- denotes [
T2112 3007-3010 CD denotes 6,7
T2113 3010-3011 -RRB- denotes ]
T2114 3012-3015 CC denotes and
T2115 3016-3020 NNP denotes AIDS
T2116 3021-3022 -LRB- denotes [
T2117 3022-3025 CD denotes 8,9
T2118 3025-3026 -RRB- denotes ]
T2119 3028-3037 NN denotes Induction
T2120 3038-3040 IN denotes of
T2121 3041-3046 NN denotes CXCL8
T2122 3047-3050 VB denotes has
T2123 3051-3055 VB denotes been
T2124 3056-3065 VB denotes suggested
T2125 3066-3068 TO denotes to
T2126 3069-3071 VB denotes be
T2127 3072-3080 VB denotes mediated
T2128 3081-3088 IN denotes through
T2129 3089-3094 NN denotes NF-κB
T2130 3095-3097 IN denotes in
T2131 3098-3109 NN denotes cooperation
T2132 3110-3114 IN denotes with
T2133 3115-3119 NN denotes AP-1
T2134 3120-3121 -LRB- denotes [
T2135 3121-3126 CD denotes 10,11
T2136 3126-3127 -RRB- denotes ]
T2137 3127-3128 -COMMA- denotes ,
T2138 3129-3136 RB denotes however
T2139 3137-3140 DT denotes the
T2140 3141-3148 JJ denotes precise
T2141 3149-3158 NN denotes mechanism
T2142 3159-3161 VB denotes is
T2143 3162-3165 RB denotes not
T2144 3166-3171 RB denotes fully
T2145 3172-3182 VB denotes elucidated
T2146 3182-3183 -COMMA- denotes ,
T2147 3184-3187 CC denotes and
T2148 3188-3197 NN denotes treatment
T2149 3198-3208 NN denotes strategies
T2150 3209-3214 VB denotes aimed
T2151 3215-3217 IN denotes at
T2152 3218-3228 VB denotes inhibiting
T2153 3229-3234 NN denotes CXCL8
T2154 3235-3239 VB denotes have
T2155 3240-3246 VB denotes failed
T2156 3247-3248 -LRB- denotes [
T2157 3248-3250 CD denotes 12
T2158 3250-3251 -RRB- denotes ]
T2159 3253-3263 JJ denotes Persistent
T2160 3264-3274 NN denotes production
T2161 3275-3277 IN denotes of
T2162 3278-3282 NN denotes IL-6
T2163 3283-3286 CC denotes and
T2164 3287-3292 NN denotes CXCL8
T2165 3293-3298 VB denotes leads
T2166 3299-3301 TO denotes to
T2167 3302-3309 JJ denotes chronic
T2168 3310-3322 NN denotes inflammation
T2169 3323-3326 CC denotes and
T2170 3327-3335 VB denotes enhanced
T2171 3336-3344 NN denotes survival
T2172 3345-3347 IN denotes of
T2173 3348-3359 NN denotes lymphocytes
T2174 3360-3370 VB denotes increasing
T2175 3371-3376 NN denotes serum
T2176 3377-3395 NN denotes cytokine/chemokine
T2177 3396-3402 NN denotes levels
T2178 3404-3408 DT denotes This
T2179 3409-3414 VB denotes forms
T2180 3415-3418 DT denotes the
T2181 3419-3424 NN denotes basis
T2182 3425-3427 IN denotes of
T2183 3428-3435 JJ denotes several
T2184 3436-3446 JJ denotes autoimmune
T2185 3447-3456 NN denotes disorders
T2186 3457-3466 VB denotes including
T2187 3467-3480 NN denotes plasmacytosis
T2188 3481-3484 CC denotes and
T2189 3485-3496 NN denotes hyperplasia
T2190 3497-3498 -LRB- denotes [
T2191 3498-3500 CD denotes 13
T2192 3500-3501 -RRB- denotes ]
T2193 3503-3505 TO denotes To
T2194 3506-3513 VB denotes develop
T2195 3514-3520 JJ denotes viable
T2196 3521-3526 NN denotes CXCL8
T2197 3527-3532 VB denotes based
T2198 3533-3542 NN denotes treatment
T2199 3543-3553 NN denotes strategies
T2200 3553-3554 -COMMA- denotes ,
T2201 3555-3557 PRP denotes it
T2202 3558-3560 VB denotes is
T2203 3561-3570 JJ denotes necessary
T2204 3571-3573 TO denotes to
T2205 3574-3582 VB denotes identify
T2206 3583-3586 DT denotes the
T2207 3587-3597 NN denotes signalling
T2208 3598-3606 NN denotes pathways
T2209 3607-3617 VB denotes regulating
T2210 3618-3623 NN denotes CXCL8
T2211 3624-3627 CC denotes and
T2212 3628-3637 VB denotes determine
T2213 3638-3641 WRB denotes how
T2214 3642-3646 DT denotes this
T2215 3647-3649 VB denotes is
T2216 3650-3657 VB denotes coupled
T2217 3658-3660 TO denotes to
T2218 3661-3666 NN denotes NF-κB
T2219 3666-3667 -COMMA- denotes ,
T2220 3668-3672 NN denotes AP-1
T2221 3673-3676 CC denotes and
T2222 3677-3681 NN denotes IL-6
T2223 3683-3686 DT denotes The
T2224 3687-3697 NN denotes signalling
T2225 3698-3706 NN denotes pathways
T2226 3707-3714 VB denotes leading
T2227 3715-3717 TO denotes to
T2228 3718-3723 NN denotes NF-κB
T2229 3724-3727 CC denotes and
T2230 3728-3732 NN denotes AP-1
T2231 3733-3743 NN denotes activation
T2232 3744-3747 VB denotes are
T2233 3748-3759 VB denotes overlapping
T2234 3759-3760 -COMMA- denotes ,
T2235 3761-3766 WRB denotes where
T2236 3767-3771 DT denotes both
T2237 3772-3775 VB denotes are
T2238 3776-3784 VB denotes involved
T2239 3785-3787 IN denotes in
T2240 3788-3791 DT denotes the
T2241 3792-3801 NN denotes induction
T2242 3802-3805 CC denotes and
T2243 3806-3816 NN denotes regulation
T2244 3817-3819 IN denotes of
T2245 3820-3840 NN denotes cytokines/chemokines
T2246 3842-3847 NN denotes NF-κB
T2247 3848-3850 VB denotes is
T2248 3851-3860 VB denotes activated
T2249 3861-3863 IN denotes in
T2250 3864-3872 NN denotes response
T2251 3873-3875 TO denotes to
T2252 3876-3882 NN denotes stress
T2253 3882-3883 -COMMA- denotes ,
T2254 3884-3888 JJ denotes such
T2255 3889-3891 IN denotes as
T2256 3892-3901 JJ denotes oxidative
T2257 3902-3908 NN denotes stress
T2258 3908-3909 -COMMA- denotes ,
T2259 3910-3919 JJ denotes bacterial
T2260 3920-3926 NN denotes toxins
T2261 3926-3927 -COMMA- denotes ,
T2262 3928-3935 NN denotes viruses
T2263 3936-3939 CC denotes and
T2264 3940-3942 NN denotes UV
T2265 3943-3948 NN denotes light
T2266 3949-3950 -LRB- denotes [
T2267 3950-3952 CD denotes 14
T2268 3952-3953 -RRB- denotes ]
T2269 3953-3954 -COMMA- denotes ,
T2270 3955-3958 CC denotes and
T2271 3959-3961 VB denotes is
T2272 3962-3971 JJ denotes essential
T2273 3972-3975 IN denotes for
T2274 3976-3991 NN denotes differentiation
T2275 3991-3992 -COMMA- denotes ,
T2276 3993-4006 NN denotes proliferation
T2277 4007-4010 CC denotes and
T2278 4011-4019 NN denotes survival
T2279 4020-4022 IN denotes of
T2280 4023-4027 JJ denotes many
T2281 4028-4032 NN denotes cell
T2282 4033-4038 NN denotes types
T2283 4039-4048 VB denotes including
T2284 4049-4062 NN denotes T-lymphocytes
T2285 4063-4064 -LRB- denotes [
T2286 4064-4066 CD denotes 15
T2287 4066-4067 -RRB- denotes ]
T2288 4069-4073 NN denotes AP-1
T2289 4074-4084 NN denotes activation
T2290 4085-4093 VB denotes requires
T2291 4094-4097 NN denotes Fos
T2292 4098-4099 -LRB- denotes (
T2293 4099-4104 NN denotes c-Fos
T2294 4104-4105 -COMMA- denotes ,
T2295 4106-4110 NN denotes FosB
T2296 4110-4111 -COMMA- denotes ,
T2297 4112-4117 NN denotes Fra-1
T2298 4117-4118 -COMMA- denotes ,
T2299 4119-4124 NN denotes Fra-2
T2300 4124-4125 -RRB- denotes )
T2301 4126-4129 CC denotes and
T2302 4130-4133 NN denotes Jun
T2303 4134-4135 -LRB- denotes (
T2304 4135-4140 NN denotes c-Jun
T2305 4140-4141 -COMMA- denotes ,
T2306 4142-4147 NN denotes v-Jun
T2307 4147-4148 -COMMA- denotes ,
T2308 4149-4153 NN denotes JunB
T2309 4153-4154 -COMMA- denotes ,
T2310 4155-4159 NN denotes JunD
T2311 4159-4160 -RRB- denotes )
T2312 4161-4168 IN denotes through
T2313 4169-4172 DT denotes the
T2314 4173-4182 NN denotes formation
T2315 4183-4185 IN denotes of
T2316 4186-4191 JJ denotes homo-
T2317 4192-4195 CC denotes and
T2318 4196-4209 NN denotes hetero-dimers
T2319 4210-4211 -LRB- denotes [
T2320 4211-4216 CD denotes 16,17
T2321 4216-4217 -RRB- denotes ]
T2322 4217-4218 -COMMA- denotes ,
T2323 4219-4222 CC denotes and
T2324 4223-4232 VB denotes regulates
T2325 4233-4246 NN denotes transcription
T2326 4247-4249 IN denotes of
T2327 4250-4251 DT denotes a
T2328 4252-4257 JJ denotes broad
T2329 4258-4263 NN denotes range
T2330 4264-4266 IN denotes of
T2331 4267-4272 NN denotes genes
T2332 4273-4281 VB denotes involved
T2333 4282-4284 IN denotes in
T2334 4285-4291 JJ denotes immune
T2335 4292-4301 NN denotes responses
T2336 4302-4303 -LRB- denotes [
T2337 4303-4308 CD denotes 18-21
T2338 4308-4309 -RRB- denotes ]
T2339 4311-4315 CC denotes Both
T2340 4316-4320 NN denotes AP-1
T2341 4321-4324 CC denotes and
T2342 4325-4330 NN denotes NF-κB
T2343 4331-4338 NN denotes binding
T2344 4339-4344 NN denotes sites
T2345 4345-4349 VB denotes have
T2346 4350-4354 VB denotes been
T2347 4355-4365 VB denotes identified
T2348 4366-4368 IN denotes in
T2349 4369-4372 DT denotes the
T2350 4373-4381 NN denotes promoter
T2351 4382-4388 NN denotes region
T2352 4389-4391 IN denotes of
T2353 4392-4396 NN denotes IL-6
T2354 4397-4400 CC denotes and
T2355 4401-4406 NN denotes CXCL8
T2356 4407-4408 -LRB- denotes [
T2357 4408-4413 CD denotes 12,22
T2358 4413-4414 -RRB- denotes ]
T2359 4414-4415 -COMMA- denotes ,
T2360 4416-4423 RB denotes however
T2361 4423-4424 -COMMA- denotes ,
T2362 4425-4428 DT denotes the
T2363 4429-4438 NN denotes mechanism
T2364 4439-4441 IN denotes by
T2365 4442-4447 WDT denotes which
T2366 4448-4453 DT denotes these
T2367 4454-4466 NN denotes interleukins
T2368 4467-4470 VB denotes are
T2369 4471-4480 VB denotes regulated
T2370 4481-4483 IN denotes in
T2371 4484-4491 NN denotes T-cells
T2372 4492-4494 VB denotes is
T2373 4495-4500 RB denotes still
T2374 4501-4504 RB denotes not
T2375 4505-4510 JJ denotes clear
T2376 4512-4517 NN denotes CXCL8
T2377 4518-4520 VB denotes is
T2378 4521-4522 DT denotes a
T2379 4523-4528 NN denotes C-X-C
T2380 4529-4538 NN denotes chemokine
T2381 4539-4543 IN denotes with
T2382 4544-4554 NN denotes properties
T2383 4555-4563 VB denotes enabling
T2384 4564-4566 PRP denotes it
T2385 4567-4569 TO denotes to
T2386 4570-4577 VB denotes recruit
T2387 4578-4585 NN denotes T-cells
T2388 4586-4589 CC denotes and
T2389 4590-4599 NN denotes basophils
T2390 4600-4603 CC denotes and
T2391 4604-4606 TO denotes to
T2392 4607-4615 VB denotes activate
T2393 4616-4627 NN denotes neutrophils
T2394 4628-4631 CC denotes and
T2395 4632-4641 NN denotes monocytes
T2396 4642-4643 -LRB- denotes [
T2397 4643-4645 CD denotes 23
T2398 4645-4646 -RRB- denotes ]
T2399 4648-4652 NN denotes IL-6
T2400 4653-4655 VB denotes is
T2401 4656-4657 DT denotes a
T2402 4658-4666 NN denotes cytokine
T2403 4667-4671 WDT denotes that
T2404 4672-4681 VB denotes possesses
T2405 4682-4686 CC denotes both
T2406 4687-4691 JJ denotes pro-
T2407 4692-4695 CC denotes and
T2408 4696-4713 JJ denotes anti-inflammatory
T2409 4714-4729 NN denotes characteristics
T2410 4730-4733 CC denotes and
T2411 4734-4738 DT denotes that
T2412 4739-4744 VB denotes plays
T2413 4745-4746 DT denotes a
T2414 4747-4750 JJ denotes key
T2415 4751-4755 NN denotes role
T2416 4756-4758 IN denotes in
T2417 4759-4773 NN denotes haematopoiesis
T2418 4774-4777 CC denotes and
T2419 4778-4789 NN denotes acute-phase
T2420 4790-4799 NN denotes responses
T2421 4800-4801 -LRB- denotes [
T2422 4801-4806 CD denotes 24,25
T2423 4806-4807 -RRB- denotes ]
T2424 4809-4812 DT denotes The
T2425 4813-4820 JJ denotes present
T2426 4821-4826 NN denotes study
T2427 4827-4835 VB denotes suggests
T2428 4836-4840 IN denotes that
T2429 4841-4844 DT denotes the
T2430 4845-4855 NN denotes regulation
T2431 4856-4858 IN denotes of
T2432 4859-4864 NN denotes CXCL8
T2433 4865-4868 CC denotes and
T2434 4869-4873 NN denotes IL-6
T2435 4874-4876 VB denotes is
T2436 4877-4886 JJ denotes uncoupled
T2437 4888-4893 VB denotes Using
T2438 4894-4900 NN denotes Jurkat
T2439 4901-4908 NN denotes T-cells
T2440 4909-4916 VB denotes exposed
T2441 4917-4919 TO denotes to
T2442 4920-4923 NN denotes PMA
T2443 4924-4927 CC denotes and
T2444 4928-4932 NN denotes heat
T2445 4933-4939 VB denotes killed
T2446 4940-4941 -LRB- denotes (
T2447 4941-4943 NN denotes HK
T2448 4943-4944 -RRB- denotes )
T2449 4945-4956 FW denotes Escherichia
T2450 4957-4961 FW denotes coli
T2451 4962-4968 NN denotes MG1655
T2452 4969-4971 IN denotes in
T2453 4972-4983 NN denotes combination
T2454 4984-4988 IN denotes with
T2455 4989-4999 NN denotes inhibitors
T2456 5000-5002 IN denotes of
T2457 5003-5008 NN denotes NF-κB
T2458 5008-5009 -COMMA- denotes ,
T2459 5010-5013 NN denotes JNK
T2460 5014-5017 CC denotes and
T2461 5018-5021 NN denotes PKC
T2462 5021-5022 -COMMA- denotes ,
T2463 5023-5025 PRP denotes we
T2464 5026-5038 VB denotes demonstrated
T2465 5039-5043 IN denotes that
T2466 5044-5049 NN denotes NF-κB
T2467 5050-5059 VB denotes regulates
T2468 5060-5064 NN denotes IL-6
T2469 5065-5075 NN denotes expression
T2470 5076-5081 IN denotes while
T2471 5082-5085 DT denotes the
T2472 5086-5096 NN denotes regulation
T2473 5097-5099 IN denotes of
T2474 5100-5105 NN denotes CXCL8
T2475 5106-5110 RB denotes more
T2476 5111-5118 RB denotes closely
T2477 5119-5129 VB denotes correlated
T2478 5130-5132 TO denotes to
T2479 5133-5137 NN denotes AP-1
T2480 5138-5146 NN denotes activity
T2481 5148-5153 DT denotes These
T2482 5154-5161 NN denotes results
T2483 5162-5170 VB denotes indicate
T2484 5171-5175 IN denotes that
T2485 5176-5186 NN denotes inhibition
T2486 5187-5189 IN denotes of
T2487 5190-5195 NN denotes NF-κB
T2488 5196-5198 VB denotes is
T2489 5199-5202 RB denotes not
T2490 5203-5205 DT denotes an
T2491 5206-5215 JJ denotes effective
T2492 5216-5224 NN denotes strategy
T2493 5225-5227 IN denotes in
T2494 5228-5238 VB denotes countering
T2495 5239-5242 DT denotes the
T2496 5243-5247 JJ denotes high
T2497 5248-5253 NN denotes CXCL8
T2498 5254-5264 NN denotes activities
T2499 5265-5267 IN denotes in
T2500 5268-5276 NN denotes diseases
T2501 5277-5281 JJ denotes such
T2502 5282-5284 IN denotes as
T2503 5285-5291 JJ denotes cystic
T2504 5292-5300 NN denotes fibrosis
T2505 5300-5301 -COMMA- denotes ,
T2506 5302-5306 NN denotes AIDS
T2507 5307-5310 CC denotes and
T2508 5311-5320 JJ denotes pulmonary
T2509 5321-5329 NN denotes fibrosis
T3422 5364-5369 NN denotes NF-κB
T3423 5370-5380 NN denotes activation
T3424 5381-5384 DT denotes The
T3425 5385-5398 NN denotes transcription
T3426 5399-5406 NN denotes factors
T3427 5407-5412 NN denotes NF-κB
T3428 5413-5416 CC denotes and
T3429 5417-5421 NN denotes AP-1
T3430 5422-5426 VB denotes play
T3431 5427-5430 JJ denotes key
T3432 5431-5436 NN denotes roles
T3433 5437-5439 IN denotes in
T3434 5440-5443 DT denotes the
T3435 5444-5454 NN denotes initiation
T3436 5455-5457 IN denotes of
T3437 5458-5460 DT denotes an
T3438 5461-5473 JJ denotes inflammatory
T3439 5474-5482 NN denotes response
T3440 5483-5485 IN denotes by
T3441 5486-5494 VB denotes inducing
T3442 5495-5498 DT denotes the
T3443 5499-5509 NN denotes expression
T3444 5510-5513 CC denotes and
T3445 5514-5523 NN denotes secretion
T3446 5524-5526 IN denotes of
T3447 5527-5537 NN denotes chemokines
T3448 5538-5541 CC denotes and
T3449 5542-5551 NN denotes cytokines
T3450 5552-5556 WDT denotes that
T3451 5557-5564 VB denotes attract
T3452 5565-5568 CC denotes and
T3453 5569-5577 VB denotes activate
T3454 5578-5584 JJ denotes immune
T3455 5585-5590 NN denotes cells
T3456 5592-5599 RB denotes However
T3457 5599-5600 -COMMA- denotes ,
T3458 5601-5604 DT denotes the
T3459 5605-5611 NN denotes signal
T3460 5612-5624 NN denotes transduction
T3461 5625-5633 NN denotes pathways
T3462 5634-5637 CC denotes and
T3463 5638-5648 JJ denotes subsequent
T3464 5649-5661 JJ denotes inflammatory
T3465 5662-5670 NN denotes cytokine
T3466 5671-5680 NN denotes induction
T3467 5681-5683 IN denotes by
T3468 5684-5689 DT denotes these
T3469 5690-5703 NN denotes transcription
T3470 5704-5711 NN denotes factors
T3471 5712-5714 VB denotes is
T3472 5715-5718 RB denotes not
T3473 5719-5724 RB denotes fully
T3474 5725-5735 VB denotes elucidated
T3475 5737-5740 DT denotes The
T3476 5741-5748 JJ denotes present
T3477 5749-5754 NN denotes study
T3478 5755-5757 VB denotes is
T3479 5758-5763 VB denotes aimed
T3480 5764-5766 IN denotes at
T3481 5767-5778 VB denotes determining
T3482 5779-5782 DT denotes the
T3483 5783-5794 NN denotes involvement
T3484 5795-5797 IN denotes of
T3485 5798-5802 NN denotes AP-1
T3486 5803-5806 CC denotes and
T3487 5807-5812 NN denotes NF-κB
T3488 5813-5815 IN denotes in
T3489 5816-5824 NN denotes cytokine
T3490 5825-5834 NN denotes induction
T3491 5835-5838 CC denotes and
T3492 5839-5849 NN denotes regulation
T3493 5851-5854 NN denotes PMA
T3494 5855-5864 NN denotes treatment
T3495 5865-5873 VB denotes resulted
T3496 5874-5876 IN denotes in
T3497 5877-5879 DT denotes an
T3498 5880-5893 NN denotes up-regulation
T3499 5894-5896 IN denotes of
T3500 5897-5901 NN denotes AP-1
T3501 5902-5907 IN denotes after
T3502 5908-5909 CD denotes 2
T3503 5910-5911 NN denotes h
T3504 5912-5920 NN denotes exposure
T3505 5921-5924 CC denotes and
T3506 5925-5934 VB denotes continued
T3507 5935-5937 TO denotes to
T3508 5938-5946 VB denotes increase
T3509 5947-5957 IN denotes throughout
T3510 5958-5961 DT denotes the
T3511 5962-5970 NN denotes analysis
T3512 5971-5977 NN denotes period
T3513 5978-5979 -LRB- denotes (
T3514 5979-5985 NN denotes figure
T3515 5986-5988 NN denotes 1a
T3516 5988-5989 -RRB- denotes )
T3517 5991-5993 NN denotes HK
T3518 5994-5996 FW denotes E.
T3519 5997-6001 FW denotes coli
T3520 6002-6011 NN denotes treatment
T3521 6012-6015 VB denotes did
T3522 6016-6019 RB denotes not
T3523 6020-6026 VB denotes affect
T3524 6027-6031 NN denotes AP-1
T3525 6032-6042 NN denotes activation
T3526 6043-6045 IN denotes in
T3527 6046-6052 NN denotes Jurkat
T3528 6053-6060 NN denotes T-cells
T3529 6061-6062 -LRB- denotes (
T3530 6062-6068 NN denotes figure
T3531 6069-6071 NN denotes 1b
T3532 6071-6072 -RRB- denotes )
T3533 6074-6076 TO denotes To
T3534 6077-6086 VB denotes determine
T3535 6087-6090 DT denotes the
T3536 6091-6102 NN denotes involvement
T3537 6103-6105 IN denotes of
T3538 6106-6116 VB denotes associated
T3539 6117-6125 NN denotes pathways
T3540 6125-6126 -COMMA- denotes ,
T3541 6127-6129 PRP denotes we
T3542 6130-6137 VB denotes exposed
T3543 6138-6143 NN denotes cells
T3544 6144-6146 TO denotes to
T3545 6147-6151 NN denotes Ca2+
T3546 6152-6161 NN denotes ionophore
T3547 6162-6166 IN denotes with
T3548 6167-6169 CC denotes or
T3549 6170-6177 IN denotes without
T3550 6178-6181 NN denotes PMA
T3551 6182-6185 CC denotes and
T3552 6186-6194 VB denotes observed
T3553 6195-6196 DT denotes a
T3554 6197-6203 JJ denotes modest
T3555 6204-6215 NN denotes involvement
T3556 6216-6218 IN denotes of
T3557 6219-6223 NN denotes Ca2+
T3558 6224-6226 IN denotes in
T3559 6227-6240 JJ denotes PMA-dependent
T3560 6241-6245 NN denotes AP-1
T3561 6246-6256 NN denotes activation
T3562 6257-6258 -LRB- denotes (
T3563 6258-6264 NN denotes figure
T3564 6265-6267 NN denotes 1c
T3565 6267-6268 -RRB- denotes )
T3566 6269-6274 IN denotes while
T3567 6275-6279 NN denotes Ca2+
T3568 6280-6285 RB denotes alone
T3569 6286-6289 VB denotes did
T3570 6290-6293 RB denotes not
T3571 6294-6299 VB denotes alter
T3572 6300-6304 NN denotes AP-1
T3573 6305-6313 NN denotes activity
T3574 6314-6315 -LRB- denotes (
T3575 6315-6319 NN denotes data
T3576 6320-6323 RB denotes not
T3577 6324-6329 VB denotes shown
T3578 6329-6330 -RRB- denotes )
T3579 6332-6343 RB denotes Furthermore
T3580 6343-6344 -COMMA- denotes ,
T3581 6345-6349 NN denotes AP-1
T3582 6350-6358 NN denotes activity
T3583 6359-6368 VB denotes decreased
T3584 6369-6371 IN denotes in
T3585 6372-6373 DT denotes a
T3586 6374-6387 JJ denotes TCR-deficient
T3587 6388-6394 NN denotes Jurkat
T3588 6395-6399 NN denotes cell
T3589 6400-6404 NN denotes line
T3590 6405-6409 WRB denotes when
T3591 6410-6417 VB denotes exposed
T3592 6418-6420 TO denotes to
T3593 6421-6424 NN denotes PMA
T3594 6425-6433 VB denotes compared
T3595 6434-6436 TO denotes to
T3596 6437-6440 DT denotes the
T3597 6441-6447 NN denotes parent
T3598 6448-6452 NN denotes cell
T3599 6453-6457 NN denotes line
T3600 6458-6468 VB denotes indicating
T3601 6469-6473 IN denotes that
T3602 6474-6484 NN denotes regulation
T3603 6485-6487 IN denotes of
T3604 6488-6492 NN denotes AP-1
T3605 6493-6496 VB denotes was
T3606 6497-6501 RB denotes only
T3607 6502-6511 RB denotes partially
T3608 6512-6518 NN denotes T-cell
T3609 6519-6527 NN denotes receptor
T3610 6528-6537 JJ denotes dependent
T3611 6538-6539 -LRB- denotes (
T3612 6539-6545 NN denotes figure
T3613 6546-6548 NN denotes 1d
T3614 6548-6549 -RRB- denotes )
T15150 6561-6565 NN denotes AP-1
T15151 6566-6576 NN denotes activation
T15152 6577-6586 VB denotes following
T15153 6587-6596 JJ denotes long-term
T15154 6597-6605 NN denotes exposure
T15155 6606-6608 IN denotes of
T15156 6609-6615 NN denotes Jurkat
T15157 6616-6623 NN denotes T-cells
T15158 6624-6626 TO denotes to
T15159 6627-6630 NN denotes PMA
T15160 6632-6638 NN denotes Jurkat
T15161 6639-6646 NN denotes T-cells
T15162 6647-6651 VB denotes were
T15163 6652-6663 VB denotes transfected
T15164 6664-6668 IN denotes with
T15165 6669-6679 NN denotes luciferase
T15166 6680-6688 NN denotes reporter
T15167 6689-6697 NN denotes plasmids
T15168 6698-6708 VB denotes containing
T15169 6709-6712 DT denotes the
T15170 6713-6717 NN denotes AP-1
T15171 6718-6731 NN denotes cis-elements.
T15172 6732-6733 -LRB- denotes (
T15173 6733-6734 NN denotes A
T15174 6734-6735 -RRB- denotes )
T15175 6736-6750 JJ denotes Time-dependent
T15176 6751-6755 NN denotes AP-1
T15177 6756-6766 NN denotes activation
T15178 6767-6769 IN denotes in
T15179 6770-6778 NN denotes response
T15180 6779-6781 TO denotes to
T15181 6782-6786 NN denotes PMA.
T15182 6787-6788 -LRB- denotes (
T15183 6788-6789 NN denotes B
T15184 6789-6790 -RRB- denotes )
T15185 6791-6793 NN denotes HK
T15186 6794-6796 FW denotes E.
T15187 6797-6801 FW denotes coli
T15188 6802-6806 VB denotes does
T15189 6807-6810 RB denotes not
T15190 6811-6819 VB denotes activate
T15191 6820-6825 NN denotes AP-1.
T15192 6826-6827 -LRB- denotes (
T15193 6827-6828 NN denotes C
T15194 6828-6829 -RRB- denotes )
T15195 6830-6844 JJ denotes Dose-dependent
T15196 6845-6855 NN denotes activation
T15197 6856-6858 IN denotes of
T15198 6859-6863 NN denotes AP-1
T15199 6864-6868 VB denotes were
T15200 6869-6878 VB denotes performed
T15201 6879-6884 VB denotes using
T15202 6885-6888 NN denotes PMA
T15203 6889-6894 RB denotes alone
T15204 6895-6896 -LRB- denotes (
T15205 6896-6900 JJ denotes grey
T15206 6901-6905 NN denotes bars
T15207 6905-6906 -RRB- denotes )
T15208 6907-6910 CC denotes and
T15209 6911-6913 IN denotes in
T15210 6914-6925 NN denotes combination
T15211 6926-6930 IN denotes with
T15212 6931-6938 NN denotes calcium
T15213 6939-6948 NN denotes ionophore
T15214 6949-6950 -LRB- denotes (
T15215 6950-6953 NN denotes CaI
T15216 6954-6957 CD denotes 955
T15217 6958-6960 NN denotes μM
T15218 6960-6961 -COMMA- denotes ,
T15219 6962-6967 JJ denotes black
T15220 6968-6972 NN denotes bars
T15221 6972-6973 -RRB- denotes )
T15222 6973-6974 -LRB- denotes .
T15223 6975-6976 NN denotes (
T15224 6976-6977 -RRB- denotes D
T15225 6977-6983 JJ denotes ) TCR-
T15226 6983-6992 JJ denotes /- defici
T15227 6992-6997 NN denotes ent c
T15228 6997-7006 VB denotes ells resp
T15229 7006-7008 TO denotes on
T15230 7008-7011 NN denotes ded
T15231 7012-7013 -LRB- denotes t
T15232 7013-7016 CD denotes o P
T15233 7016-7018 NN denotes MA
T15234 7019-7020 -RRB- denotes (
T15235 7020-7022 IN denotes 16
T15236 7022-7035 VB denotes 2 nM) by up-r
T15237 7035-7039 NN denotes egul
T15238 7039-7047 NN denotes ating AP
T15239 7060-7071 JJ denotes Statistical
T15240 7072-7084 NN denotes significance
T15241 7085-7089 IN denotes from
T15242 7090-7093 DT denotes the
T15243 7094-7101 NN denotes control
T15244 7102-7105 VB denotes was
T15245 7106-7116 VB denotes determined
T15246 7117-7122 VB denotes using
T15247 7123-7130 NN denotes Student
T15248 7130-7132 POS denotes 's
T15249 7133-7140 NN denotes t-test.
T15250 7141-7142 -LRB- denotes (
T15251 7142-7143 NN denotes n
T15252 7144-7145 SYM denotes =
T15253 7146-7147 CD denotes 4
T15254 7147-7148 -RRB- denotes )
T15255 7150-7158 NN denotes Controls
T15256 7159-7163 VB denotes were
T15257 7164-7175 RB denotes arbitrarily
T15258 7176-7179 VB denotes set
T15259 7180-7182 TO denotes to
T15260 7183-7184 CD denotes 1
T3615 7188-7193 NN denotes NF-κB
T3616 7194-7200 NN denotes levels
T3617 7201-7207 VB denotes showed
T3618 7208-7209 DT denotes a
T3619 7210-7219 JJ denotes transient
T3620 7220-7228 NN denotes increase
T3621 7229-7231 IN denotes at
T3622 7232-7233 CD denotes 1
T3623 7234-7237 NN denotes min
T3624 7238-7243 IN denotes after
T3625 7244-7252 NN denotes exposure
T3626 7253-7255 TO denotes to
T3627 7256-7259 NN denotes PMA
T3628 7260-7261 -LRB- denotes (
T3629 7261-7267 NN denotes figure
T3630 7268-7270 NN denotes 2a
T3631 7270-7271 -RRB- denotes )
T3632 7273-7280 RB denotes However
T3633 7280-7281 -COMMA- denotes ,
T3634 7282-7283 CD denotes 1
T3635 7284-7285 NN denotes h
T3636 7286-7291 IN denotes after
T3637 7292-7300 NN denotes exposure
T3638 7301-7304 DT denotes the
T3639 7305-7310 NN denotes NF-κB
T3640 7311-7317 NN denotes levels
T3641 7318-7323 VB denotes began
T3642 7324-7326 TO denotes to
T3643 7327-7331 VB denotes drop
T3644 7332-7340 VB denotes reaching
T3645 7341-7344 DT denotes the
T3646 7345-7351 JJ denotes lowest
T3647 7352-7358 NN denotes levels
T3648 7359-7361 IN denotes by
T3649 7362-7363 CD denotes 6
T3650 7364-7365 NN denotes h
T3651 7365-7366 -COMMA- denotes ,
T3652 7367-7372 IN denotes after
T3653 7373-7378 WDT denotes which
T3654 7379-7383 PRP denotes they
T3655 7384-7393 VB denotes increased
T3656 7394-7399 RB denotes again
T3657 7400-7402 IN denotes by
T3658 7403-7405 CD denotes 24
T3659 7406-7407 NN denotes h
T3660 7409-7417 NN denotes Exposure
T3661 7418-7420 IN denotes of
T3662 7421-7427 NN denotes Jurkat
T3663 7428-7435 NN denotes T-cells
T3664 7436-7438 TO denotes to
T3665 7439-7441 NN denotes HK
T3666 7442-7444 NNP denotes E.
T3667 7445-7449 FW denotes coli
T3668 7450-7458 VB denotes resulted
T3669 7459-7461 IN denotes in
T3670 7462-7463 DT denotes a
T3671 7464-7478 JJ denotes dose-dependent
T3672 7479-7484 NN denotes NF-κB
T3673 7485-7495 NN denotes activation
T3674 7495-7496 -COMMA- denotes ,
T3675 7497-7501 IN denotes with
T3676 7502-7505 DT denotes the
T3677 7506-7513 JJ denotes highest
T3678 7514-7522 NN denotes activity
T3679 7523-7531 VB denotes observed
T3680 7532-7534 IN denotes at
T3681 7535-7536 DT denotes a
T3682 7537-7545 JJ denotes relative
T3683 7546-7559 NN denotes concentration
T3684 7560-7562 IN denotes of
T3685 7563-7564 CD denotes 5
T3686 7565-7566 -COLON- denotes ×
T3687 7567-7570 CD denotes 107
T3688 7571-7577 NNP denotes CFU/ml
T3689 7578-7579 -LRB- denotes (
T3690 7579-7585 NN denotes figure
T3691 7586-7588 NN denotes 2b
T3692 7588-7589 -RRB- denotes )
T3693 7591-7594 DT denotes The
T3694 7595-7609 JJ denotes time-dependent
T3695 7610-7620 NN denotes activation
T3696 7621-7623 IN denotes of
T3697 7624-7629 NN denotes NF-κB
T3698 7630-7632 IN denotes by
T3699 7633-7635 NN denotes HK
T3700 7636-7638 FW denotes E.
T3701 7639-7643 FW denotes coli
T3702 7644-7647 VB denotes was
T3703 7648-7656 VB denotes assessed
T3704 7657-7664 RB denotes further
T3705 7665-7670 VB denotes using
T3706 7671-7674 DT denotes the
T3707 7675-7682 JJ denotes optimal
T3708 7683-7696 NN denotes concentration
T3709 7697-7705 VB denotes obtained
T3710 7706-7710 IN denotes from
T3711 7711-7717 NN denotes figure
T3712 7718-7720 NN denotes 2b
T3713 7721-7724 CC denotes and
T3714 7725-7731 VB denotes showed
T3715 7732-7736 IN denotes that
T3716 7737-7740 DT denotes the
T3717 7741-7746 NN denotes NF-κB
T3718 7747-7755 NN denotes activity
T3719 7756-7765 VB denotes increased
T3720 7766-7771 IN denotes after
T3721 7772-7773 CD denotes 3
T3722 7774-7775 NN denotes h
T3723 7776-7778 IN denotes of
T3724 7779-7787 NN denotes exposure
T3725 7788-7789 -LRB- denotes (
T3726 7789-7795 NN denotes figure
T3727 7796-7798 NN denotes 2c
T3728 7798-7799 -RRB- denotes )
T3729 7801-7812 RB denotes Furthermore
T3730 7812-7813 -COMMA- denotes ,
T3731 7814-7823 VB denotes increased
T3732 7824-7837 JJ denotes intracellular
T3733 7838-7842 NN denotes Ca2+
T3734 7843-7851 VB denotes reversed
T3735 7852-7855 DT denotes the
T3736 7856-7859 NN denotes PMA
T3737 7860-7869 JJ denotes dependent
T3738 7870-7875 NN denotes NF-κB
T3739 7876-7886 NN denotes inhibition
T3740 7887-7888 -LRB- denotes (
T3741 7888-7894 NN denotes figure
T3742 7895-7897 NN denotes 2d
T3743 7897-7898 -RRB- denotes )
T3744 7899-7902 CC denotes and
T3745 7903-7910 VB denotes reduced
T3746 7911-7914 DT denotes the
T3747 7915-7917 NN denotes HK
T3748 7918-7920 FW denotes E.
T3749 7921-7925 FW denotes coli
T3750 7926-7936 JJ denotes -dependent
T3751 7937-7942 NN denotes NF-κB
T3752 7943-7953 NN denotes activation
T3753 7954-7955 -LRB- denotes (
T3754 7955-7961 NN denotes figure
T3755 7962-7964 NN denotes 2e
T3756 7964-7965 -RRB- denotes )
T15425 7977-7982 NN denotes NF-κB
T15426 7983-7998 NN denotes down-regulation
T15427 7999-8001 IN denotes by
T15428 8002-8005 NN denotes PMA
T15429 8006-8009 CC denotes and
T15430 8010-8023 NN denotes up-regulation
T15431 8024-8026 IN denotes by
T15432 8027-8031 NN denotes heat
T15433 8032-8038 VB denotes killed
T15434 8039-8041 FW denotes E.
T15435 8042-8046 FW denotes coli
T15436 8047-8053 NN denotes MG1655
T15437 8054-8063 VB denotes following
T15438 8064-8073 JJ denotes long-term
T15439 8074-8085 NN denotes stimulation
T15440 8087-8099 NN denotes Transfection
T15441 8100-8102 IN denotes of
T15442 8103-8109 NN denotes Jurkat
T15443 8110-8117 NN denotes T-cells
T15444 8118-8121 VB denotes was
T15445 8122-8131 VB denotes performed
T15446 8132-8137 VB denotes using
T15447 8138-8148 NN denotes luciferase
T15448 8149-8157 NN denotes reporter
T15449 8158-8166 NN denotes plasmids
T15450 8167-8177 VB denotes containing
T15451 8178-8183 NN denotes NF-κB
T15452 8184-8197 NN denotes cis-elements.
T15453 8198-8199 -LRB- denotes (
T15454 8199-8200 NN denotes A
T15455 8200-8201 -RRB- denotes )
T15456 8202-8216 JJ denotes Time-dependent
T15457 8217-8228 NN denotes stimulation
T15458 8229-8231 IN denotes of
T15459 8232-8238 NN denotes Jurkat
T15460 8239-8246 NN denotes T-cells
T15461 8247-8252 VB denotes using
T15462 8253-8256 NN denotes PMA
T15463 8258-8263 NN denotes NF-κB
T15464 8264-8274 NN denotes activation
T15465 8275-8278 VB denotes was
T15466 8279-8288 VB denotes evaluated
T15467 8289-8294 VB denotes using
T15468 8295-8297 NNP denotes HK
T15469 8298-8300 NNP denotes E.
T15470 8301-8305 NNP denotes coli
T15471 8306-8308 IN denotes in
T15472 8309-8310 DT denotes a
T15473 8311-8312 -LRB- denotes (
T15474 8312-8313 NN denotes B
T15475 8313-8314 -RRB- denotes )
T15476 8315-8320 NN denotes dose-
T15477 8321-8324 CC denotes and
T15478 8325-8326 -LRB- denotes (
T15479 8326-8327 NN denotes C
T15480 8327-8328 -RRB- denotes )
T15481 8329-8343 JJ denotes time-dependant
T15482 8344-8350 NN denotes manner
T15483 8352-8359 NN denotes Calcium
T15484 8360-8369 NN denotes ionophore
T15485 8370-8379 VB denotes increased
T15486 8380-8385 NN denotes NF-κB
T15487 8386-8394 NN denotes activity
T15488 8395-8404 VB denotes following
T15489 8405-8408 NN denotes PMA
T15490 8409-8417 NN denotes exposure
T15491 8418-8419 -LRB- denotes (
T15492 8419-8420 NN denotes E
T15493 8420-8421 -RRB- denotes )
T15494 8422-8425 CC denotes and
T15495 8426-8434 VB denotes resulted
T15496 8435-8437 IN denotes in
T15497 8438-8439 DT denotes a
T15498 8440-8448 JJ denotes negative
T15499 8449-8459 NN denotes regulation
T15500 8460-8462 IN denotes in
T15501 8463-8471 NN denotes response
T15502 8472-8474 TO denotes to
T15503 8475-8477 NN denotes HK
T15504 8478-8480 FW denotes E.
T15505 8481-8485 FW denotes coli
T15506 8486-8497 NN denotes stimulation
T15507 8498-8499 -LRB- denotes (
T15508 8499-8500 NN denotes D
T15509 8500-8501 -RRB- denotes )
T15510 8503-8514 JJ denotes Statistical
T15511 8515-8527 NN denotes significance
T15512 8528-8532 IN denotes from
T15513 8533-8536 DT denotes the
T15514 8537-8544 NN denotes control
T15515 8545-8548 VB denotes was
T15516 8549-8559 VB denotes determined
T15517 8560-8565 VB denotes using
T15518 8566-8573 NN denotes Student
T15519 8573-8575 POS denotes 's
T15520 8576-8583 NN denotes t-test.
T15521 8584-8585 -LRB- denotes (
T15522 8585-8586 NN denotes n
T15523 8587-8588 SYM denotes =
T15524 8589-8590 CD denotes 4
T15525 8590-8591 -RRB- denotes )
T15526 8593-8601 NN denotes Controls
T15527 8602-8606 VB denotes were
T15528 8607-8618 RB denotes arbitrarily
T15529 8619-8622 VB denotes set
T15530 8623-8625 TO denotes to
T15531 8626-8627 CD denotes 1
T4162 8630-8639 NN denotes Induction
T4163 8640-8642 IN denotes of
T4164 8643-8655 JJ denotes inflammatory
T4165 8656-8665 NN denotes responses
T4166 8666-8669 DT denotes The
T4167 8670-8677 NN denotes ability
T4168 8678-8680 IN denotes of
T4169 8681-8684 NN denotes PMA
T4170 8685-8688 CC denotes and
T4171 8689-8691 NN denotes HK
T4172 8692-8694 FW denotes E.
T4173 8695-8699 FW denotes coli
T4174 8700-8702 TO denotes to
T4175 8703-8709 VB denotes induce
T4176 8710-8712 DT denotes an
T4177 8713-8725 JJ denotes inflammatory
T4178 8726-8734 NN denotes response
T4179 8735-8737 IN denotes in
T4180 8738-8744 NN denotes Jurkat
T4181 8745-8752 NN denotes T-cells
T4182 8753-8756 VB denotes was
T4183 8757-8766 VB denotes evaluated
T4184 8767-8772 VB denotes using
T4185 8773-8774 DT denotes a
T4186 8775-8784 JJ denotes multiplex
T4187 8785-8793 NN denotes cytokine
T4188 8794-8799 NN denotes assay
T4189 8800-8809 VB denotes following
T4190 8810-8812 CD denotes 24
T4191 8813-8814 NN denotes h
T4192 8815-8826 NN denotes stimulation
T4193 8828-8831 DT denotes The
T4194 8832-8840 NN denotes cytokine
T4195 8841-8848 NN denotes profile
T4196 8849-8857 VB denotes revealed
T4197 8858-8860 DT denotes an
T4198 8861-8869 VB denotes enhanced
T4199 8870-8879 NN denotes induction
T4200 8880-8882 IN denotes of
T4201 8883-8886 DT denotes the
T4202 8887-8903 JJ denotes pro-inflammatory
T4203 8904-8913 NN denotes cytokines
T4204 8914-8918 NN denotes IL-2
T4205 8918-8919 -COMMA- denotes ,
T4206 8920-8924 NN denotes IL-6
T4207 8924-8925 -COMMA- denotes ,
T4208 8926-8929 NN denotes TNF
T4209 8930-8933 CC denotes and
T4210 8934-8937 DT denotes the
T4211 8938-8947 NN denotes chemokine
T4212 8948-8953 NN denotes CXCL8
T4213 8955-8958 DT denotes The
T4214 8959-8965 NN denotes levels
T4215 8966-8968 IN denotes of
T4216 8969-8972 DT denotes the
T4217 8973-8990 JJ denotes anti-inflammatory
T4218 8991-8999 NN denotes cytokine
T4219 9000-9005 NN denotes IL-10
T4220 9006-9010 VB denotes were
T4221 9011-9021 JJ denotes unaffected
T4222 9022-9024 IN denotes by
T4223 9025-9028 NN denotes PMA
T4224 9029-9032 CC denotes but
T4225 9033-9037 VB denotes were
T4226 9038-9051 RB denotes significantly
T4227 9052-9061 VB denotes decreased
T4228 9062-9064 IN denotes by
T4229 9065-9067 NN denotes HK
T4230 9068-9070 FW denotes E.
T4231 9071-9075 FW denotes coli
T4232 9076-9077 -LRB- denotes (
T4233 9077-9082 JJ denotes Table
T4234 9083-9084 CD denotes 1
T4235 9084-9085 -RRB- denotes )
T4236 9087-9092 DT denotes These
T4237 9093-9100 NN denotes results
T4238 9101-9110 VB denotes confirmed
T4239 9111-9115 IN denotes that
T4240 9116-9119 NN denotes PMA
T4241 9120-9123 CC denotes and
T4242 9124-9126 NN denotes HK
T4243 9127-9129 FW denotes E.
T4244 9130-9134 FW denotes coli
T4245 9135-9142 VB denotes induced
T4246 9143-9145 DT denotes an
T4247 9146-9158 JJ denotes inflammatory
T4248 9159-9167 NN denotes response
T4249 9168-9170 IN denotes in
T4250 9171-9174 DT denotes the
T4251 9175-9181 NN denotes Jurkat
T4252 9182-9189 NN denotes T-cells
T4253 9191-9193 PRP denotes It
T4254 9194-9196 VB denotes is
T4255 9197-9208 JJ denotes interesting
T4256 9209-9211 TO denotes to
T4257 9212-9216 VB denotes note
T4258 9217-9221 DT denotes that
T4259 9222-9225 NN denotes PMA
T4260 9226-9229 VB denotes was
T4261 9230-9238 RB denotes 120-fold
T4262 9239-9243 RB denotes more
T4263 9244-9253 JJ denotes effective
T4264 9254-9256 IN denotes at
T4265 9257-9265 VB denotes inducing
T4266 9266-9271 NN denotes CXCL8
T4267 9272-9276 IN denotes than
T4268 9277-9279 NN denotes HK
T4269 9280-9282 FW denotes E.
T4270 9283-9287 FW denotes coli
T4271 9289-9302 JJ denotes PMA-dependent
T4272 9303-9312 NN denotes induction
T4273 9313-9315 IN denotes of
T4274 9316-9320 NN denotes AP-1
T4275 9321-9324 CC denotes and
T4276 9325-9340 NN denotes down-regulation
T4277 9341-9343 IN denotes of
T4278 9344-9349 NN denotes NF-κB
T4279 9350-9358 VB denotes suggests
T4280 9359-9361 DT denotes an
T4281 9362-9373 NN denotes involvement
T4282 9374-9376 IN denotes of
T4283 9377-9381 NN denotes AP-1
T4284 9382-9384 IN denotes in
T4285 9385-9390 NN denotes CXCL8
T4286 9391-9401 NN denotes regulation
T4287 9403-9416 NN denotes Determination
T4288 9417-9419 IN denotes of
T4289 9420-9423 DT denotes the
T4290 9424-9428 NN denotes time
T4291 9429-9435 NN denotes course
T4292 9436-9438 IN denotes of
T4293 9439-9447 NN denotes cytokine
T4294 9448-9457 NN denotes induction
T4295 9458-9460 IN denotes in
T4296 9461-9469 NN denotes response
T4297 9470-9472 TO denotes to
T4298 9473-9476 NN denotes PMA
T4299 9477-9483 VB denotes showed
T4300 9484-9488 IN denotes that
T4301 9489-9494 NN denotes CXCL8
T4302 9495-9498 VB denotes was
T4303 9499-9506 RB denotes already
T4304 9507-9515 VB denotes released
T4305 9516-9523 IN denotes between
T4306 9524-9527 CD denotes 2-6
T4307 9528-9529 NN denotes h
T4308 9529-9530 -COMMA- denotes ,
T4309 9531-9536 IN denotes while
T4310 9537-9540 NN denotes TNF
T4311 9541-9544 CC denotes and
T4312 9545-9549 NN denotes IL-6
T4313 9550-9554 VB denotes were
T4314 9555-9563 VB denotes released
T4315 9564-9571 IN denotes between
T4316 9572-9576 CD denotes 6-24
T4317 9577-9578 NN denotes h
T4318 9579-9580 -LRB- denotes (
T4319 9580-9586 NN denotes figure
T4320 9587-9588 CD denotes 3
T4321 9588-9589 -RRB- denotes )
T4322 9591-9596 DT denotes These
T4323 9597-9604 NN denotes results
T4324 9605-9614 VB denotes indicated
T4325 9615-9619 IN denotes that
T4326 9620-9623 DT denotes the
T4327 9624-9633 NN denotes cytokines
T4328 9634-9638 VB denotes were
T4329 9639-9653 RB denotes differentially
T4330 9654-9663 VB denotes regulated
T4331 9664-9667 CC denotes and
T4332 9668-9672 IN denotes that
T4333 9673-9676 DT denotes the
T4334 9677-9684 NN denotes release
T4335 9685-9688 VB denotes was
T4336 9689-9692 RB denotes not
T4337 9693-9703 VB denotes associated
T4338 9704-9708 IN denotes with
T4339 9709-9712 DT denotes the
T4340 9713-9718 JJ denotes early
T4341 9719-9728 JJ denotes transient
T4342 9729-9738 NN denotes induction
T4343 9739-9741 IN denotes of
T4344 9742-9747 NN denotes NF-κB
T4345 9749-9752 DT denotes The
T4346 9753-9761 JJ denotes temporal
T4347 9762-9771 NN denotes induction
T4348 9772-9774 IN denotes of
T4349 9775-9779 NN denotes AP-1
T4350 9780-9790 VB denotes correlated
T4351 9791-9793 TO denotes to
T4352 9794-9797 DT denotes the
T4353 9798-9803 NN denotes CXCL8
T4354 9804-9810 NN denotes levels
T4355 9811-9814 CC denotes and
T4356 9815-9823 VB denotes preceded
T4357 9824-9827 DT denotes the
T4358 9828-9831 NN denotes TNF
T4359 9832-9835 CC denotes and
T4360 9836-9840 NN denotes IL-6
T4361 9841-9848 NN denotes release
T4362 9850-9854 DT denotes This
T4363 9855-9863 VB denotes suggests
T4364 9864-9866 DT denotes an
T4365 9867-9878 NN denotes association
T4366 9879-9886 IN denotes between
T4367 9887-9892 NN denotes CXCL8
T4368 9893-9900 NN denotes release
T4369 9901-9904 CC denotes and
T4370 9905-9909 NN denotes AP-1
T4371 9910-9920 NN denotes signalling
T15704 9932-9937 NN denotes CXCL8
T15705 9937-9938 -COMMA- denotes ,
T15706 9939-9943 NN denotes IL-6
T15707 9944-9947 CC denotes and
T15708 9948-9951 NN denotes TNF
T15709 9952-9962 NN denotes expression
T15710 9963-9972 VB denotes following
T15711 9973-9982 JJ denotes long-term
T15712 9983-9994 NN denotes stimulation
T15713 9995-9999 IN denotes with
T15714 10000-10003 NN denotes PMA
T15715 10005-10011 NN denotes Jurkat
T15716 10012-10019 NN denotes T-cells
T15717 10020-10024 VB denotes were
T15718 10025-10031 RB denotes either
T15719 10032-10039 VB denotes treated
T15720 10040-10044 IN denotes with
T15721 10045-10050 NN denotes media
T15722 10051-10052 -LRB- denotes (
T15723 10052-10057 JJ denotes white
T15724 10058-10062 NN denotes bars
T15725 10062-10063 -RRB- denotes )
T15726 10064-10066 CC denotes or
T15727 10067-10077 VB denotes stimulated
T15728 10078-10082 IN denotes with
T15729 10083-10086 NN denotes PMA
T15730 10087-10088 -LRB- denotes (
T15731 10088-10093 JJ denotes black
T15732 10094-10098 NN denotes bars
T15733 10098-10099 -RRB- denotes )
T15734 10100-10103 CC denotes and
T15735 10104-10113 VB denotes incubated
T15736 10114-10117 IN denotes for
T15737 10118-10119 CD denotes 1
T15738 10120-10121 NN denotes h
T15739 10121-10122 -COMMA- denotes ,
T15740 10123-10124 CD denotes 2
T15741 10125-10126 NN denotes h
T15742 10126-10127 -COMMA- denotes ,
T15743 10128-10129 CD denotes 6
T15744 10130-10131 NN denotes h
T15745 10132-10135 CC denotes and
T15746 10136-10138 CD denotes 24
T15747 10139-10140 NN denotes h
T15748 10142-10146 JJ denotes Aged
T15749 10147-10152 NN denotes media
T15750 10153-10156 VB denotes was
T15751 10157-10162 VB denotes added
T15752 10163-10172 VB denotes following
T15753 10173-10177 DT denotes each
T15754 10178-10192 NN denotes centrifugation
T15755 10193-10197 NN denotes step
T15756 10198-10212 JJ denotes representative
T15757 10213-10215 TO denotes to
T15758 10216-10219 DT denotes the
T15759 10220-10231 NN denotes stimulation
T15760 10232-10236 NN denotes time
T15761 10237-10238 -LRB- denotes (
T15762 10238-10241 VB denotes see
T15763 10242-10251 NNP denotes Materials
T15764 10252-10255 CC denotes and
T15765 10256-10263 NN denotes methods
T15766 10263-10264 -RRB- denotes )
T15767 10266-10274 NN denotes Cytokine
T15768 10275-10281 NN denotes levels
T15769 10282-10283 -LRB- denotes (
T15770 10283-10284 NN denotes A
T15771 10284-10285 -RRB- denotes )
T15772 10286-10291 NN denotes CXCL8
T15773 10291-10292 -COMMA- denotes ,
T15774 10293-10294 -LRB- denotes (
T15775 10294-10295 NN denotes B
T15776 10295-10296 -RRB- denotes )
T15777 10297-10301 NN denotes IL-6
T15778 10302-10305 CC denotes and
T15779 10306-10307 -LRB- denotes (
T15780 10307-10308 NN denotes C
T15781 10308-10309 -RRB- denotes )
T15782 10310-10313 NN denotes TNF
T15783 10314-10318 VB denotes were
T15784 10319-10327 VB denotes detected
T15785 10328-10330 IN denotes by
T15786 10331-10336 NN denotes ELISA
T15787 10338-10349 JJ denotes Statistical
T15788 10350-10362 NN denotes significance
T15789 10363-10367 IN denotes from
T15790 10368-10371 DT denotes the
T15791 10372-10379 NN denotes control
T15792 10380-10383 VB denotes was
T15793 10384-10394 VB denotes determined
T15794 10395-10400 VB denotes using
T15795 10401-10408 NN denotes Student
T15796 10408-10410 POS denotes 's
T15797 10411-10418 NN denotes t-test.
T15798 10419-10420 -LRB- denotes (
T15799 10420-10421 NN denotes n
T15800 10422-10423 SYM denotes =
T15801 10424-10425 CD denotes 3
T15802 10425-10426 -RRB- denotes )
T17025 10437-10443 NN denotes Jurkat
T17026 10444-10451 NN denotes T-cells
T17027 10452-10456 VB denotes were
T17028 10457-10467 VB denotes stimulated
T17029 10468-10472 IN denotes with
T17030 10473-10476 CD denotes 162
T17031 10477-10479 NN denotes nM
T17032 10480-10483 NN denotes PMA
T17033 10484-10487 CC denotes and
T17034 10488-10489 CD denotes 5
T17035 10490-10491 NN denotes ×
T17036 10492-10495 CD denotes 107
T17037 10496-10502 NNP denotes CFU/ml
T17038 10503-10505 NNP denotes HK
T17039 10506-10508 NNP denotes E.
T17040 10509-10513 NNP denotes coli
T17041 10514-10517 IN denotes for
T17042 10518-10520 CD denotes 24
T17043 10521-10522 NN denotes h
T5145 10742-10753 JJ denotes Cooperative
T5146 10754-10763 NN denotes induction
T5147 10764-10766 IN denotes of
T5148 10767-10776 NN denotes cytokines
T5149 10777-10779 IN denotes by
T5150 10780-10784 NN denotes AP-1
T5151 10785-10788 CC denotes and
T5152 10789-10794 NN denotes NF-κB
T5153 10795-10797 TO denotes To
T5154 10798-10805 RB denotes further
T5155 10806-10818 VB denotes characterize
T5156 10819-10822 DT denotes the
T5157 10823-10834 NN denotes involvement
T5158 10835-10837 IN denotes of
T5159 10838-10843 NN denotes NF-κB
T5160 10844-10846 IN denotes in
T5161 10847-10855 NN denotes cytokine
T5162 10856-10866 NN denotes regulation
T5163 10866-10867 -COMMA- denotes ,
T5164 10868-10870 PRP denotes we
T5165 10871-10878 VB denotes treated
T5166 10879-10884 NN denotes cells
T5167 10885-10889 IN denotes with
T5168 10890-10892 DT denotes an
T5169 10893-10898 NN denotes NF-κB
T5170 10899-10909 NN denotes activation
T5171 10910-10919 NN denotes inhibitor
T5172 10920-10921 -LRB- denotes (
T5173 10921-10924 NN denotes NAI
T5174 10924-10925 -RRB- denotes )
T5175 10927-10930 DT denotes The
T5176 10931-10938 NN denotes results
T5177 10939-10945 VB denotes showed
T5178 10946-10950 IN denotes that
T5179 10951-10954 NN denotes NAI
T5180 10955-10966 RB denotes selectively
T5181 10967-10981 VB denotes down-regulated
T5182 10982-10987 NN denotes NF-κB
T5183 10988-10998 NN denotes activation
T5184 10999-11000 -LRB- denotes (
T5185 11000-11007 NN denotes figures
T5186 11008-11010 NN denotes 4a
T5187 11011-11014 CC denotes and
T5188 11015-11017 NN denotes 4b
T5189 11017-11018 -RRB- denotes )
T5190 11019-11022 CC denotes and
T5191 11023-11026 VB denotes did
T5192 11027-11030 RB denotes not
T5193 11031-11036 VB denotes alter
T5194 11037-11041 NN denotes AP-1
T5195 11042-11050 NN denotes activity
T5196 11051-11052 -LRB- denotes (
T5197 11052-11059 NN denotes figures
T5198 11060-11062 NN denotes 4c
T5199 11063-11066 CC denotes and
T5200 11067-11069 NN denotes 4d
T5201 11069-11070 -RRB- denotes )
T5202 11072-11080 NN denotes Exposure
T5203 11081-11083 IN denotes of
T5204 11084-11090 NN denotes Jurkat
T5205 11091-11098 NN denotes T-cells
T5206 11099-11101 TO denotes to
T5207 11102-11105 NN denotes NAI
T5208 11106-11114 VB denotes resulted
T5209 11115-11117 IN denotes in
T5210 11118-11119 DT denotes a
T5211 11120-11126 JJ denotes modest
T5212 11127-11136 NN denotes reduction
T5213 11137-11139 IN denotes of
T5214 11140-11145 NN denotes CXCL8
T5215 11146-11155 VB denotes following
T5216 11156-11159 NN denotes PMA
T5217 11160-11168 NN denotes exposure
T5218 11168-11169 -COMMA- denotes ,
T5219 11170-11175 IN denotes while
T5220 11176-11178 PRP denotes it
T5221 11179-11182 VB denotes did
T5222 11183-11186 RB denotes not
T5223 11187-11192 VB denotes alter
T5224 11193-11196 DT denotes the
T5225 11197-11202 NN denotes CXCL8
T5226 11203-11210 NN denotes release
T5227 11211-11220 VB denotes following
T5228 11221-11223 NN denotes HK
T5229 11224-11226 FW denotes E.
T5230 11227-11231 FW denotes coli
T5231 11232-11240 NN denotes exposure
T5232 11241-11242 -LRB- denotes (
T5233 11242-11248 NN denotes figure
T5234 11249-11251 NN denotes 5a
T5235 11251-11252 -RRB- denotes )
T5236 11254-11257 NN denotes NAI
T5237 11258-11261 VB denotes did
T5238 11262-11265 RB denotes not
T5239 11266-11272 VB denotes affect
T5240 11273-11276 NN denotes TNF
T5241 11277-11287 NN denotes expression
T5242 11288-11289 -LRB- denotes (
T5243 11289-11295 NN denotes figure
T5244 11296-11298 NN denotes 5b
T5245 11298-11299 -RRB- denotes )
T5246 11300-11310 VB denotes indicating
T5247 11311-11315 IN denotes that
T5248 11316-11321 NN denotes NF-κB
T5249 11322-11324 VB denotes is
T5250 11325-11328 RB denotes not
T5251 11329-11332 DT denotes the
T5252 11333-11337 JJ denotes main
T5253 11338-11347 NN denotes regulator
T5254 11348-11350 IN denotes of
T5255 11351-11356 NN denotes CXCL8
T5256 11357-11359 CC denotes or
T5257 11360-11363 NN denotes TNF
T5258 11364-11373 VB denotes following
T5259 11374-11380 CC denotes either
T5260 11381-11384 NN denotes PMA
T5261 11385-11387 CC denotes or
T5262 11388-11390 NN denotes HK
T5263 11391-11393 FW denotes E.
T5264 11394-11398 FW denotes coli
T5265 11399-11407 NN denotes exposure
T5266 11408-11410 IN denotes in
T5267 11411-11417 NN denotes Jurkat
T5268 11418-11425 NN denotes T-cells
T5269 11427-11429 IN denotes In
T5270 11430-11438 NN denotes contrast
T5271 11438-11439 -COMMA- denotes ,
T5272 11440-11443 NN denotes NAI
T5273 11444-11452 VB denotes resulted
T5274 11453-11455 IN denotes in
T5275 11456-11457 DT denotes a
T5276 11458-11466 JJ denotes complete
T5277 11467-11477 NN denotes inhibition
T5278 11478-11480 IN denotes of
T5279 11481-11485 NN denotes IL-6
T5280 11486-11495 VB denotes following
T5281 11496-11499 NN denotes PMA
T5282 11500-11508 NN denotes exposure
T5283 11509-11512 CC denotes and
T5284 11513-11514 DT denotes a
T5285 11515-11517 CD denotes 45
T5286 11517-11518 NN denotes %
T5287 11519-11529 NN denotes inhibition
T5288 11530-11539 VB denotes following
T5289 11540-11542 NN denotes HK
T5290 11543-11545 FW denotes E.
T5291 11546-11550 FW denotes coli
T5292 11551-11559 NN denotes exposure
T5293 11560-11561 -LRB- denotes (
T5294 11561-11567 NN denotes figure
T5295 11568-11570 NN denotes 5c
T5296 11570-11571 -RRB- denotes )
T5297 11571-11572 -COMMA- denotes ,
T5298 11573-11583 VB denotes suggesting
T5299 11584-11586 DT denotes an
T5300 11587-11598 NN denotes involvement
T5301 11599-11601 IN denotes of
T5302 11602-11607 NN denotes NF-κB
T5303 11608-11610 IN denotes in
T5304 11611-11615 NN denotes IL-6
T5305 11616-11626 NN denotes regulation
T15991 11638-11648 NN denotes Inhibition
T15992 11649-11651 IN denotes of
T15993 11652-11657 NN denotes NF-κB
T15994 11658-11666 NN denotes activity
T15995 11667-11669 IN denotes by
T15996 11670-11673 NN denotes NAI
T15997 11675-11681 NN denotes Jurkat
T15998 11682-11689 NN denotes T-cells
T15999 11690-11694 VB denotes were
T16000 11695-11706 VB denotes transfected
T16001 11707-11711 IN denotes with
T16002 11712-11722 NN denotes luciferase
T16003 11723-11731 NN denotes reporter
T16004 11732-11740 NN denotes plasmids
T16005 11741-11751 VB denotes containing
T16006 11752-11758 CC denotes either
T16007 11759-11764 NN denotes NF-κB
T16008 11765-11767 CC denotes or
T16009 11768-11772 NN denotes AP-1
T16010 11773-11783 JJ denotes cis-acting
T16011 11784-11792 NN denotes elements
T16012 11794-11797 DT denotes The
T16013 11798-11803 NN denotes cells
T16014 11804-11808 VB denotes were
T16015 11809-11818 VB denotes incubated
T16016 11819-11823 IN denotes with
T16017 11824-11829 NN denotes NF-κB
T16018 11830-11840 NN denotes activation
T16019 11841-11850 NN denotes inhibitor
T16020 11851-11852 -LRB- denotes (
T16021 11852-11855 NN denotes NAI
T16022 11855-11856 -RRB- denotes )
T16023 11857-11860 IN denotes for
T16024 11861-11862 CD denotes 1
T16025 11863-11864 NN denotes h
T16026 11865-11873 VB denotes followed
T16027 11874-11876 IN denotes by
T16028 11877-11888 NN denotes stimulation
T16029 11889-11893 IN denotes with
T16030 11894-11897 NN denotes PMA
T16031 11898-11899 -LRB- denotes (
T16032 11899-11902 CD denotes 162
T16033 11903-11905 NN denotes nM
T16034 11905-11906 -COMMA- denotes ,
T16035 11907-11908 NN denotes A
T16036 11909-11912 CC denotes and
T16037 11913-11914 NN denotes C
T16038 11914-11915 -RRB- denotes )
T16039 11916-11918 CC denotes or
T16040 11919-11921 NN denotes HK
T16041 11922-11924 FW denotes E.
T16042 11925-11929 FW denotes coli
T16043 11930-11931 -LRB- denotes (
T16044 11931-11932 CD denotes 5
T16045 11933-11934 NN denotes ×
T16046 11935-11938 CD denotes 107
T16047 11939-11945 NNP denotes CFU/ml
T16048 11945-11946 -COMMA- denotes ,
T16049 11947-11948 NN denotes B
T16050 11949-11952 CC denotes and
T16051 11953-11954 NN denotes D
T16052 11954-11955 -RRB- denotes )
T16053 11956-11959 IN denotes for
T16054 11960-11962 CD denotes 24
T16055 11963-11965 NN denotes h.
T16056 11966-11967 -LRB- denotes (
T16057 11967-11968 NN denotes A
T16058 11968-11969 -COMMA- denotes ,
T16059 11970-11971 NN denotes B
T16060 11971-11972 -RRB- denotes )
T16061 11973-11978 NN denotes NF-κB
T16062 11978-11979 -COMMA- denotes ,
T16063 11980-11983 CC denotes but
T16064 11984-11987 RB denotes not
T16065 11988-11989 -LRB- denotes (
T16066 11989-11990 NN denotes C
T16067 11990-11991 -COMMA- denotes ,
T16068 11992-11993 NN denotes D
T16069 11993-11994 -RRB- denotes )
T16070 11995-11999 NN denotes AP-1
T16071 12000-12003 VB denotes was
T16072 12004-12013 VB denotes inhibited
T16073 12015-12026 JJ denotes Statistical
T16074 12027-12039 NN denotes significance
T16075 12040-12044 IN denotes from
T16076 12045-12048 DT denotes the
T16077 12049-12057 JJ denotes positive
T16078 12058-12065 NN denotes control
T16079 12066-12067 -LRB- denotes (
T16080 12067-12073 NN denotes PMA/HK
T16081 12074-12076 FW denotes E.
T16082 12077-12081 FW denotes coli
T16083 12081-12082 -RRB- denotes )
T16084 12083-12086 VB denotes was
T16085 12087-12097 VB denotes determined
T16086 12098-12103 VB denotes using
T16087 12104-12111 NN denotes Student
T16088 12111-12113 POS denotes 's
T16089 12114-12121 NN denotes t-test.
T16090 12122-12123 -LRB- denotes (
T16091 12123-12124 NN denotes n
T16092 12125-12126 SYM denotes =
T16093 12127-12128 CD denotes 4
T16094 12128-12129 -RRB- denotes )
T16095 12131-12139 NN denotes Controls
T16096 12140-12144 VB denotes were
T16097 12145-12148 VB denotes set
T16098 12149-12151 TO denotes to
T16099 12152-12153 CD denotes 1
T5306 12925-12929 NN denotes Ca2+
T5307 12930-12933 VB denotes was
T5308 12934-12942 VB denotes observed
T5309 12943-12945 TO denotes to
T5310 12946-12954 VB denotes increase
T5311 12955-12959 NN denotes AP-1
T5312 12960-12968 NN denotes activity
T5313 12969-12970 -LRB- denotes (
T5314 12970-12976 NN denotes figure
T5315 12977-12979 NN denotes 1c
T5316 12979-12980 -RRB- denotes )
T5317 12981-12984 CC denotes and
T5318 12985-12991 VB denotes reduce
T5319 12992-12997 NN denotes NF-κB
T5320 12998-13006 NN denotes activity
T5321 13007-13008 -LRB- denotes (
T5322 13008-13014 NN denotes figure
T5323 13015-13017 NN denotes 2e
T5324 13017-13018 -RRB- denotes )
T5325 13018-13019 -COLON- denotes ;
T5326 13020-13029 RB denotes therefore
T5327 13029-13030 -COMMA- denotes ,
T5328 13031-13033 PRP denotes we
T5329 13034-13041 VB denotes exposed
T5330 13042-13049 NN denotes T-cells
T5331 13050-13052 TO denotes to
T5332 13053-13054 DT denotes a
T5333 13055-13058 NN denotes PKC
T5334 13059-13068 NN denotes inhibitor
T5335 13069-13077 RB denotes together
T5336 13078-13082 IN denotes with
T5337 13083-13086 NN denotes PMA
T5338 13087-13089 TO denotes to
T5339 13090-13099 VB denotes determine
T5340 13100-13103 PRP-DOLLAR- denotes its
T5341 13104-13110 NN denotes effect
T5342 13111-13113 IN denotes on
T5343 13114-13122 NN denotes cytokine
T5344 13123-13133 NN denotes expression
T5345 13135-13145 NN denotes Inhibition
T5346 13146-13148 IN denotes of
T5347 13149-13152 NN denotes PKC
T5348 13153-13160 VB denotes reduced
T5349 13161-13166 NN denotes CXCL8
T5350 13167-13174 NN denotes release
T5351 13175-13179 IN denotes from
T5352 13180-13181 CD denotes 7
T5353 13182-13187 NN denotes ng/ml
T5354 13188-13190 TO denotes to
T5355 13191-13192 CD denotes 3
T5356 13193-13198 NN denotes ng/ml
T5357 13199-13204 IN denotes while
T5358 13205-13207 PRP denotes it
T5359 13208-13211 VB denotes had
T5360 13212-13213 DT denotes a
T5361 13214-13220 JJ denotes modest
T5362 13221-13227 NN denotes effect
T5363 13228-13230 IN denotes on
T5364 13231-13235 NN denotes IL-6
T5365 13236-13239 CC denotes and
T5366 13240-13243 NN denotes TNF
T5367 13244-13245 -LRB- denotes (
T5368 13245-13251 NN denotes figure
T5369 13252-13256 NN denotes 6a-c
T5370 13256-13257 -RRB- denotes )
T5371 13259-13263 DT denotes This
T5372 13264-13272 VB denotes prompted
T5373 13273-13275 PRP denotes us
T5374 13276-13278 TO denotes to
T5375 13279-13283 VB denotes test
T5376 13284-13287 DT denotes the
T5377 13288-13294 NN denotes effect
T5378 13295-13297 IN denotes of
T5379 13298-13301 NN denotes JNK
T5380 13302-13312 NN denotes inhibition
T5381 13313-13315 IN denotes on
T5382 13316-13327 JJ denotes PMA-induced
T5383 13328-13336 NN denotes cytokine
T5384 13337-13347 NN denotes expression
T5385 13349-13352 NN denotes JNK
T5386 13353-13355 VB denotes is
T5387 13356-13364 VB denotes involved
T5388 13365-13367 IN denotes in
T5389 13368-13371 DT denotes the
T5390 13372-13382 NN denotes regulation
T5391 13383-13385 IN denotes of
T5392 13386-13387 DT denotes a
T5393 13388-13397 NN denotes multitude
T5394 13398-13400 IN denotes of
T5395 13401-13410 JJ denotes different
T5396 13411-13424 NN denotes transcription
T5397 13425-13432 NN denotes factors
T5398 13432-13433 -COMMA- denotes ,
T5399 13434-13443 VB denotes including
T5400 13444-13447 DT denotes the
T5401 13448-13463 NN denotes phosphorylation
T5402 13464-13467 CC denotes and
T5403 13468-13478 NN denotes activation
T5404 13479-13481 IN denotes of
T5405 13482-13487 NN denotes c-Jun
T5406 13487-13488 -COMMA- denotes ,
T5407 13489-13494 NN denotes c-Fos
T5408 13495-13498 CC denotes and
T5409 13499-13502 NN denotes p53
T5410 13502-13503 -COMMA- denotes ,
T5411 13504-13511 VB denotes leading
T5412 13512-13514 TO denotes to
T5413 13515-13523 JJ denotes cellular
T5414 13524-13533 NN denotes apoptosis
T5415 13534-13535 -LRB- denotes [
T5416 13535-13537 CD denotes 26
T5417 13537-13538 -RRB- denotes ]
T5418 13540-13550 NN denotes Inhibition
T5419 13551-13553 IN denotes of
T5420 13554-13557 DT denotes the
T5421 13558-13561 NN denotes JNK
T5422 13562-13570 NN denotes pathways
T5423 13571-13579 VB denotes resulted
T5424 13580-13582 IN denotes in
T5425 13583-13584 DT denotes a
T5426 13585-13600 NN denotes down-regulation
T5427 13601-13603 IN denotes of
T5428 13604-13608 CC denotes both
T5429 13609-13614 NN denotes CXCL8
T5430 13615-13618 CC denotes and
T5431 13619-13623 NN denotes IL-6
T5432 13623-13624 -COMMA- denotes ,
T5433 13625-13630 IN denotes while
T5434 13631-13633 DT denotes no
T5435 13634-13639 JJ denotes clear
T5436 13640-13646 NN denotes effect
T5437 13647-13650 VB denotes was
T5438 13651-13659 VB denotes observed
T5439 13660-13662 IN denotes on
T5440 13663-13666 NN denotes TNF
T5441 13667-13677 NN denotes expression
T5442 13678-13679 -LRB- denotes (
T5443 13679-13685 NN denotes figure
T5444 13686-13690 NN denotes 6a-c
T5445 13690-13691 -RRB- denotes )
T5446 13693-13701 NN denotes Analysis
T5447 13702-13704 IN denotes of
T5448 13705-13709 NN denotes mRNA
T5449 13710-13716 NN denotes levels
T5450 13717-13722 VB denotes using
T5451 13723-13730 NN denotes RT-qPCR
T5452 13731-13732 -LRB- denotes (
T5453 13732-13737 NN denotes table
T5454 13738-13739 CD denotes 2
T5455 13739-13740 -RRB- denotes )
T5456 13741-13747 VB denotes showed
T5457 13748-13752 IN denotes that
T5458 13753-13756 NN denotes PMA
T5459 13757-13764 VB denotes induced
T5460 13765-13769 CC denotes both
T5461 13770-13774 NN denotes il-6
T5462 13775-13778 CC denotes and
T5463 13779-13784 NN denotes cxcl8
T5464 13785-13789 NN denotes mRNA
T5465 13790-13791 -LRB- denotes (
T5466 13791-13799 JJ denotes 5.1-fold
T5467 13800-13803 CC denotes and
T5468 13804-13809 CD denotes 111.8
T5469 13810-13814 RB denotes fold
T5470 13815-13827 RB denotes respectively
T5471 13827-13828 -RRB- denotes )
T5472 13830-13838 NN denotes Addition
T5473 13839-13841 IN denotes of
T5474 13842-13845 DT denotes the
T5475 13846-13851 NN denotes NF-κB
T5476 13852-13861 NN denotes inhibitor
T5477 13862-13865 NN denotes NAI
T5478 13866-13869 CC denotes and
T5479 13870-13873 DT denotes the
T5480 13874-13877 NN denotes JNK
T5481 13878-13887 NN denotes inhibitor
T5482 13888-13895 VB denotes reduced
T5483 13896-13899 DT denotes the
T5484 13900-13904 NN denotes il-6
T5485 13905-13915 NN denotes expression
T5486 13916-13921 IN denotes below
T5487 13922-13927 JJ denotes basal
T5488 13928-13934 NN denotes levels
T5489 13936-13938 IN denotes In
T5490 13939-13947 NN denotes contrast
T5491 13947-13948 -COMMA- denotes ,
T5492 13949-13954 IN denotes while
T5493 13955-13958 DT denotes the
T5494 13959-13964 NN denotes cxcl8
T5495 13965-13971 NN denotes levels
T5496 13972-13976 VB denotes were
T5497 13977-13987 VB denotes suppressed
T5498 13988-13990 IN denotes by
T5499 13991-13994 DT denotes the
T5500 13995-13999 JJ denotes same
T5501 14000-14010 NN denotes treatments
T5502 14011-14014 DT denotes the
T5503 14015-14021 NN denotes levels
T5504 14022-14030 VB denotes remained
T5505 14031-14039 JJ denotes elevated
T5506 14040-14045 IN denotes above
T5507 14046-14051 JJ denotes basal
T5508 14052-14057 NN denotes level
T16538 14069-14080 NN denotes Involvement
T16539 14081-14083 IN denotes of
T16540 14084-14087 NN denotes PKC
T16541 14088-14091 CC denotes and
T16542 14092-14095 NN denotes JNK
T16543 14096-14098 IN denotes in
T16544 14099-14107 NN denotes cytokine
T16545 14108-14118 NN denotes expression
T16546 14120-14126 NN denotes Jurkat
T16547 14127-14134 NN denotes T-cells
T16548 14135-14139 VB denotes were
T16549 14140-14149 VB denotes incubated
T16550 14150-14154 IN denotes with
T16551 14155-14159 NN denotes PKC-
T16552 14160-14163 CC denotes and
T16553 14164-14167 NN denotes JNK
T16554 14168-14178 NN denotes inhibitors
T16555 14179-14182 IN denotes for
T16556 14183-14184 CD denotes 1
T16557 14185-14186 NN denotes h
T16558 14187-14195 VB denotes followed
T16559 14196-14198 IN denotes by
T16560 14199-14210 NN denotes stimulation
T16561 14211-14215 IN denotes with
T16562 14216-14219 NN denotes PMA
T16563 14220-14221 -LRB- denotes (
T16564 14221-14224 CD denotes 162
T16565 14225-14227 NN denotes nM
T16566 14227-14228 -RRB- denotes )
T16567 14229-14232 IN denotes for
T16568 14233-14235 CD denotes 24
T16569 14236-14238 NN denotes h.
T16570 14239-14240 -LRB- denotes (
T16571 14240-14241 NN denotes A
T16572 14241-14242 -RRB- denotes )
T16573 14243-14248 NN denotes CXCL8
T16574 14249-14259 NN denotes expression
T16575 14260-14263 VB denotes was
T16576 14264-14273 VB denotes inhibited
T16577 14274-14276 IN denotes in
T16578 14277-14278 DT denotes a
T16579 14279-14293 JJ denotes dose-dependent
T16580 14294-14300 NN denotes manner
T16581 14301-14303 IN denotes by
T16582 14304-14308 CC denotes both
T16583 14309-14320 NN denotes inhibitors.
T16584 14321-14322 -LRB- denotes (
T16585 14322-14323 NN denotes B
T16586 14323-14324 -RRB- denotes )
T16587 14325-14330 NN denotes JNK-I
T16588 14331-14339 VB denotes revealed
T16589 14340-14341 DT denotes a
T16590 14342-14350 JJ denotes stronger
T16591 14351-14361 JJ denotes inhibitory
T16592 14362-14368 NN denotes effect
T16593 14369-14371 IN denotes on
T16594 14372-14376 NN denotes IL-6
T16595 14377-14387 NN denotes expression
T16596 14388-14392 IN denotes than
T16597 14393-14396 DT denotes the
T16598 14397-14403 NN denotes PKC-I.
T16599 14404-14405 -LRB- denotes (
T16600 14405-14406 NN denotes C
T16601 14406-14407 -RRB- denotes )
T16602 14408-14411 NN denotes TNF
T16603 14412-14422 NN denotes expression
T16604 14423-14426 VB denotes was
T16605 14427-14430 RB denotes not
T16606 14431-14439 VB denotes affected
T16607 14440-14442 IN denotes by
T16608 14443-14449 DT denotes either
T16609 14450-14459 NN denotes inhibitor
T16610 14461-14472 JJ denotes Statistical
T16611 14473-14485 NN denotes significance
T16612 14486-14490 IN denotes from
T16613 14491-14494 DT denotes the
T16614 14495-14503 JJ denotes positive
T16615 14504-14511 NN denotes control
T16616 14512-14513 -LRB- denotes (
T16617 14513-14516 NN denotes PMA
T16618 14516-14517 -RRB- denotes )
T16619 14518-14521 VB denotes was
T16620 14522-14532 VB denotes determined
T16621 14533-14538 VB denotes using
T16622 14539-14546 NN denotes Student
T16623 14546-14548 POS denotes 's
T16624 14549-14556 NN denotes t-test.
T16625 14557-14558 -LRB- denotes (
T16626 14558-14559 NN denotes n
T16627 14560-14561 SYM denotes =
T16628 14562-14563 CD denotes 3
T16629 14563-14564 -RRB- denotes )
T17075 14575-14581 NN denotes Jurkat
T17076 14582-14589 NN denotes T-cells
T17077 14590-14594 VB denotes were
T17078 14595-14602 VB denotes treated
T17079 14603-14607 IN denotes with
T17080 14608-14610 CD denotes 10
T17081 14611-14613 NN denotes nM
T17082 14614-14617 NN denotes NAI
T17083 14617-14618 -COMMA- denotes ,
T17084 14619-14621 CD denotes 10
T17085 14622-14624 NN denotes μM
T17086 14625-14630 NN denotes JNK-I
T17087 14631-14635 NN denotes or10
T17088 14636-14638 NN denotes nM
T17089 14639-14644 NN denotes PKC-I
T17090 14645-14648 IN denotes for
T17091 14649-14650 CD denotes 2
T17092 14651-14652 NN denotes h
T17093 14653-14661 VB denotes followed
T17094 14662-14664 IN denotes by
T17095 14665-14674 NN denotes induction
T17096 14675-14679 IN denotes with
T17097 14680-14683 CD denotes 162
T17098 14684-14686 NN denotes nM
T17099 14687-14690 NN denotes PMA
T17100 14691-14694 IN denotes for
T17101 14695-14697 CD denotes 24
T17102 14698-14699 NN denotes h
T6147 14966-14971 NN denotes NF-κB
T6148 14972-14982 NN denotes inhibition
T6149 14983-14986 JJ denotes due
T6150 14987-14989 TO denotes to
T6151 14990-15003 JJ denotes PKC-dependent
T6152 15004-15009 NN denotes Bcl10
T6153 15010-15021 NN denotes degradation
T6154 15022-15029 NN denotes Western
T6155 15030-15034 NN denotes blot
T6156 15035-15043 NN denotes analysis
T6157 15044-15052 VB denotes revealed
T6158 15053-15055 DT denotes an
T6159 15056-15069 NN denotes up-regulation
T6160 15070-15072 IN denotes of
T6161 15073-15091 NN denotes phosphorylated-PKC
T6162 15092-15097 IN denotes after
T6163 15098-15100 CD denotes 24
T6164 15101-15102 NN denotes h
T6165 15103-15112 NN denotes treatment
T6166 15113-15115 IN denotes of
T6167 15116-15122 NN denotes Jurkat
T6168 15123-15130 NN denotes T-cells
T6169 15131-15135 IN denotes with
T6170 15136-15139 NN denotes PMA
T6171 15140-15142 CC denotes or
T6172 15143-15145 NN denotes HK
T6173 15146-15148 FW denotes E.
T6174 15149-15153 FW denotes coli
T6175 15154-15155 -LRB- denotes (
T6176 15155-15161 NN denotes figure
T6177 15162-15164 NN denotes 7a
T6178 15164-15165 -RRB- denotes )
T6179 15165-15166 -COMMA- denotes ,
T6180 15167-15172 IN denotes while
T6181 15173-15177 NN denotes IκBβ
T6182 15178-15184 NN denotes levels
T6183 15185-15193 VB denotes remained
T6184 15194-15204 JJ denotes unaffected
T6185 15205-15206 -LRB- denotes (
T6186 15206-15212 NN denotes figure
T6187 15213-15215 NN denotes 7b
T6188 15215-15216 -RRB- denotes )
T6189 15218-15223 NN denotes Bcl10
T6190 15224-15226 VB denotes is
T6191 15227-15228 DT denotes a
T6192 15229-15239 NN denotes signalling
T6193 15240-15247 NN denotes protein
T6194 15248-15252 WDT denotes that
T6195 15253-15257 VB denotes acts
T6196 15258-15266 RB denotes upstream
T6197 15267-15269 IN denotes of
T6198 15270-15275 NN denotes NF-κB
T6199 15276-15278 IN denotes in
T6200 15279-15286 NN denotes concert
T6201 15287-15291 IN denotes with
T6202 15292-15298 NN denotes CARMA1
T6203 15299-15302 CC denotes and
T6204 15303-15308 NN denotes MALT1
T6205 15309-15312 CC denotes and
T6206 15313-15316 VB denotes has
T6207 15317-15321 VB denotes been
T6208 15322-15331 VB denotes suggested
T6209 15332-15334 TO denotes to
T6210 15335-15343 RB denotes directly
T6211 15344-15352 VB denotes regulate
T6212 15353-15358 NN denotes NF-κB
T6213 15359-15367 NN denotes activity
T6214 15368-15370 IN denotes in
T6215 15371-15378 NN denotes T-cells
T6216 15379-15380 -LRB- denotes [
T6217 15380-15382 CD denotes 27
T6218 15382-15383 -RRB- denotes ]
T6219 15385-15394 RB denotes Therefore
T6220 15394-15395 -COMMA- denotes ,
T6221 15396-15401 NN denotes Bcl10
T6222 15402-15412 NN denotes activation
T6223 15413-15416 VB denotes was
T6224 15417-15426 VB denotes evaluated
T6225 15427-15429 IN denotes in
T6226 15430-15434 CC denotes both
T6227 15435-15442 NN denotes control
T6228 15443-15446 CC denotes and
T6229 15447-15450 NN denotes PMA
T6230 15451-15461 JJ denotes stimulated
T6231 15462-15467 NN denotes cells
T6232 15468-15473 IN denotes after
T6233 15474-15476 CD denotes 10
T6234 15477-15480 NN denotes min
T6235 15480-15481 -COMMA- denotes ,
T6236 15482-15483 CD denotes 1
T6237 15484-15485 NN denotes h
T6238 15485-15486 -COMMA- denotes ,
T6239 15487-15488 CD denotes 6
T6240 15489-15490 NN denotes h
T6241 15490-15491 -COMMA- denotes ,
T6242 15492-15495 CC denotes and
T6243 15496-15498 CD denotes 24
T6244 15499-15500 NN denotes h
T6245 15501-15506 VB denotes using
T6246 15507-15514 JJ denotes western
T6247 15515-15519 NN denotes blot
T6248 15520-15528 NN denotes analysis
T6249 15530-15533 DT denotes The
T6250 15534-15539 NN denotes Bcl10
T6251 15540-15546 NN denotes levels
T6252 15547-15556 VB denotes decreased
T6253 15557-15566 VB denotes following
T6254 15567-15576 NN denotes treatment
T6255 15577-15581 IN denotes with
T6256 15582-15585 NN denotes PMA
T6257 15585-15586 -COMMA- denotes ,
T6258 15587-15592 IN denotes while
T6259 15593-15595 IN denotes in
T6260 15596-15603 NN denotes control
T6261 15604-15609 NN denotes cells
T6262 15609-15610 -COMMA- denotes ,
T6263 15611-15616 NN denotes Bcl10
T6264 15617-15625 VB denotes returned
T6265 15626-15628 TO denotes to
T6266 15629-15635 JJ denotes higher
T6267 15636-15642 NN denotes levels
T6268 15643-15645 IN denotes by
T6269 15646-15648 CD denotes 24
T6270 15649-15650 NN denotes h
T6271 15651-15652 -LRB- denotes (
T6272 15652-15658 NN denotes figure
T6273 15659-15661 NN denotes 7c
T6274 15661-15662 -RRB- denotes )
T6275 15664-15668 DT denotes This
T6276 15669-15677 VB denotes suggests
T6277 15678-15682 IN denotes that
T6278 15683-15688 NN denotes Bcl10
T6279 15689-15691 VB denotes is
T6280 15692-15700 VB denotes involved
T6281 15701-15703 IN denotes in
T6282 15704-15707 DT denotes the
T6283 15708-15711 NN denotes PMA
T6284 15712-15721 JJ denotes dependent
T6285 15722-15732 NN denotes inhibition
T6286 15733-15735 IN denotes of
T6287 15736-15741 NN denotes NF-κB
T6288 15742-15752 NN denotes activation
T16839 15764-15769 NN denotes NF-κB
T16840 15770-15780 NN denotes inhibition
T16841 15781-15783 IN denotes by
T16842 15784-15787 NN denotes PMA
T16843 15788-15798 VB denotes correlated
T16844 15799-15801 TO denotes to
T16845 15802-15815 JJ denotes PKC-dependent
T16846 15816-15821 NN denotes Bcl10
T16847 15822-15833 NN denotes degradation
T16848 15835-15841 NN denotes Levels
T16849 15842-15844 IN denotes of
T16850 15845-15858 JJ denotes intracellular
T16851 15859-15866 NN denotes protein
T16852 15867-15871 VB denotes were
T16853 15872-15880 VB denotes assessed
T16854 15881-15890 VB denotes following
T16855 15891-15893 CD denotes 24
T16856 15894-15895 NN denotes h
T16857 15896-15907 NN denotes stimulation
T16858 15908-15912 IN denotes with
T16859 15913-15916 NN denotes PMA
T16860 15917-15918 -LRB- denotes (
T16861 15918-15921 CD denotes 162
T16862 15922-15924 NN denotes nM
T16863 15924-15925 -RRB- denotes )
T16864 15926-15928 CC denotes or
T16865 15929-15931 NN denotes HK
T16866 15932-15934 FW denotes E.
T16867 15935-15939 FW denotes coli
T16868 15940-15941 -LRB- denotes (
T16869 15941-15942 CD denotes 5
T16870 15943-15944 NN denotes ×
T16871 15945-15948 CD denotes 107
T16872 15949-15955 NNP denotes CFU/ml
T16873 15955-15956 -RRB- denotes )
T16874 15956-15957 -LRB- denotes .
T16875 15958-15959 NN denotes (
T16876 15959-15960 -RRB- denotes A
T16877 15960-15971 NN denotes ) Phospho-P
T16878 15971-15980 VB denotes KC increa
T16879 15980-15982 IN denotes se
T16880 15982-15990 NN denotes d in res
T16881 15990-15992 TO denotes po
T16882 15992-15995 NN denotes nse
T16883 15996-15999 CC denotes to
T16884 15999-16001 NN denotes PM
T16885 16001-16003 FW denotes A
T16886 16003-16007 FW denotes and
T16887 16007-16019 NN denotes HK E. coli s
T16888 16019-16020 -LRB- denotes t
T16889 16020-16021 NN denotes i
T16890 16021-16022 -RRB- denotes m
T16891 16022-16025 NN denotes ula
T16892 16025-16034 VB denotes tion. (B)
T16893 16035-16044 VB denotes IκB decre
T16894 16044-16055 NN denotes ased follow
T16895 16055-16059 IN denotes ing
T16896 16059-16061 NN denotes st
T16897 16061-16063 FW denotes im
T16898 16063-16067 FW denotes ulat
T16899 16067-16077 VB denotes ion with H
T16900 16077-16082 NN denotes K E.
T16901 16082-16093 NN denotes coli indica
T16902 16093-16094 -LRB- denotes t
T16903 16094-16095 NN denotes i
T16904 16095-16096 -RRB- denotes n
T16905 16096-16101 NN denotes g NF-
T16906 16101-16111 NN denotes κB activat
T16907 16111-16114 VB denotes ion
T16908 16114-16123 VB denotes . (C) Bcl
T16909 16123-16132 VB denotes 10 activa
T16910 16132-16141 JJ denotes tion was
T16911 16141-16152 NN denotes inhibited f
T16912 16152-16156 IN denotes ollo
T16913 16156-16159 NN denotes win
T16914 16159-16160 -COMMA- denotes g
T16915 16161-16166 WDT denotes long-
T16916 16166-16174 VB denotes term sti
T16917 16174-16177 DT denotes mul
T16918 16177-16187 JJ denotes ation with
T16919 16188-16194 NN denotes PMA, w
T16920 16194-16196 IN denotes hi
T16921 16196-16199 NN denotes ch
T16922 16199-16201 IN denotes ex
T16923 16201-16206 NN denotes plain
T16924 16206-16217 NN denotes s the inhib
T16925 16217-16224 NN denotes itory e
T16926 16224-16227 VB denotes ffe
T16927 16227-16231 VB denotes ct o
T16928 16231-16233 IN denotes f
T16929 16233-16234 DT denotes P
T16930 16234-16241 NN denotes MA on N
T16931 16241-16249 NN denotes F-κB act
T16932 16249-16250 -LRB- denotes i
T16933 16250-16251 NN denotes v
T16934 16251-16252 SYM denotes a
T16935 16252-16253 CD denotes t
T16936 16253-16254 -RRB- denotes i
T8442 16318-16323 NN denotes NF-κB
T8443 16324-16327 CC denotes and
T8444 16328-16332 NN denotes AP-1
T8445 16333-16336 VB denotes are
T8446 16337-16345 JJ denotes critical
T8447 16346-16356 NN denotes regulators
T8448 16357-16359 IN denotes of
T8449 16360-16372 JJ denotes inflammatory
T8450 16373-16382 NN denotes responses
T8451 16382-16383 -COMMA- denotes ,
T8452 16384-16397 NN denotes proliferation
T8453 16398-16401 CC denotes and
T8454 16402-16417 NN denotes differentiation
T8455 16418-16420 IN denotes of
T8456 16421-16428 NN denotes T-cells
T8457 16429-16430 -LRB- denotes [
T8458 16430-16435 CD denotes 28-30
T8459 16435-16436 -RRB- denotes ]
T8460 16436-16437 -COMMA- denotes ,
T8461 16438-16445 RB denotes however
T8462 16445-16446 -COMMA- denotes ,
T8463 16447-16450 DT denotes the
T8464 16451-16457 NN denotes signal
T8465 16458-16470 NN denotes transduction
T8466 16471-16474 CC denotes and
T8467 16475-16485 JJ denotes subsequent
T8468 16486-16504 NN denotes cytokine/chemokine
T8469 16505-16515 NN denotes expression
T8470 16516-16518 VB denotes is
T8471 16519-16522 RB denotes not
T8472 16523-16528 RB denotes fully
T8473 16529-16539 VB denotes understood
T8474 16541-16544 DT denotes The
T8475 16545-16548 NN denotes aim
T8476 16549-16551 IN denotes of
T8477 16552-16555 DT denotes the
T8478 16556-16563 JJ denotes present
T8479 16564-16569 NN denotes study
T8480 16570-16573 VB denotes was
T8481 16574-16576 TO denotes to
T8482 16577-16588 VB denotes investigate
T8483 16589-16593 NN denotes IL-6
T8484 16594-16597 CC denotes and
T8485 16598-16603 NN denotes CXCL8
T8486 16604-16614 NN denotes regulation
T8487 16615-16617 IN denotes by
T8488 16618-16623 NN denotes NF-κB
T8489 16624-16627 CC denotes and
T8490 16628-16632 NN denotes AP-1
T8491 16633-16635 IN denotes in
T8492 16636-16642 NN denotes Jurkat
T8493 16643-16650 NN denotes T-cells
T8494 16652-16655 PRP-DOLLAR- denotes Our
T8495 16656-16663 NN denotes results
T8496 16664-16676 VB denotes demonstrated
T8497 16677-16681 IN denotes that
T8498 16682-16685 NN denotes PMA
T8499 16686-16693 VB denotes induced
T8500 16694-16698 NN denotes AP-1
T8501 16699-16709 NN denotes activation
T8502 16709-16710 -COMMA- denotes ,
T8503 16711-16721 VB denotes indicating
T8504 16722-16723 DT denotes a
T8505 16724-16732 JJ denotes specific
T8506 16733-16743 NN denotes activation
T8507 16744-16746 IN denotes of
T8508 16747-16750 DT denotes the
T8509 16751-16755 NN denotes MAPK
T8510 16756-16763 NN denotes pathway
T8511 16765-16776 RB denotes Furthermore
T8512 16776-16777 -COMMA- denotes ,
T8513 16778-16780 PRP denotes we
T8514 16781-16793 VB denotes demonstrated
T8515 16794-16798 IN denotes that
T8516 16799-16802 NN denotes PMA
T8517 16803-16812 JJ denotes dependent
T8518 16813-16817 NN denotes AP-1
T8519 16818-16828 NN denotes activation
T8520 16829-16831 IN denotes in
T8521 16832-16839 NN denotes T-cells
T8522 16840-16843 VB denotes was
T8523 16844-16851 VB denotes delayed
T8524 16852-16853 -LRB- denotes (
T8525 16853-16854 SYM denotes >
T8526 16854-16855 CD denotes 2
T8527 16856-16857 NN denotes h
T8528 16857-16858 -RRB- denotes )
T8529 16859-16862 CC denotes and
T8530 16863-16872 VB denotes increased
T8531 16873-16882 VB denotes following
T8532 16883-16892 JJ denotes long-term
T8533 16893-16902 NN denotes treatment
T8534 16904-16908 NN denotes MAPK
T8535 16909-16911 VB denotes is
T8536 16912-16915 CD denotes one
T8537 16916-16918 IN denotes of
T8538 16919-16922 DT denotes the
T8539 16923-16927 JJ denotes main
T8540 16928-16938 NN denotes signalling
T8541 16939-16947 NN denotes pathways
T8542 16948-16950 IN denotes in
T8543 16951-16958 NN denotes T-cells
T8544 16959-16963 WDT denotes that
T8545 16964-16972 VB denotes regulate
T8546 16973-16978 NN denotes cell-
T8547 16979-16982 CC denotes and
T8548 16983-16998 JJ denotes transcriptional
T8549 16999-17009 NN denotes activation
T8550 17010-17011 -LRB- denotes [
T8551 17011-17016 CD denotes 31,32
T8552 17016-17017 -RRB- denotes ]
T8553 17019-17026 JJ denotes Several
T8554 17027-17034 NN denotes studies
T8555 17035-17036 -LRB- denotes [
T8556 17036-17044 CD denotes 20,33,34
T8557 17044-17045 -RRB- denotes ]
T8558 17046-17050 VB denotes have
T8559 17051-17060 VB denotes indicated
T8560 17061-17064 DT denotes the
T8561 17065-17075 NN denotes importance
T8562 17076-17078 IN denotes of
T8563 17079-17083 NN denotes AP-1
T8564 17084-17086 IN denotes in
T8565 17087-17093 NN denotes T-cell
T8566 17094-17104 NN denotes activation
T8567 17105-17108 CC denotes and
T8568 17109-17112 DT denotes the
T8569 17113-17122 NN denotes induction
T8570 17123-17125 IN denotes of
T8571 17126-17138 JJ denotes inflammatory
T8572 17139-17148 NN denotes responses
T8573 17149-17150 -LRB- denotes [
T8574 17150-17152 CD denotes 35
T8575 17152-17153 -RRB- denotes ]
T8576 17153-17154 -COMMA- denotes ,
T8577 17155-17164 VB denotes including
T8578 17165-17181 JJ denotes pro-inflammatory
T8579 17182-17190 NN denotes cytokine
T8580 17191-17198 NN denotes release
T8581 17200-17202 IN denotes In
T8582 17203-17211 NN denotes contrast
T8583 17212-17214 TO denotes to
T8584 17215-17219 NN denotes AP-1
T8585 17219-17220 -COMMA- denotes ,
T8586 17221-17226 NN denotes NF-κB
T8587 17227-17235 NN denotes activity
T8588 17236-17243 RB denotes rapidly
T8589 17244-17253 VB denotes increased
T8590 17254-17255 -LRB- denotes (
T8591 17255-17256 CD denotes 1
T8592 17257-17260 NN denotes min
T8593 17260-17261 -RRB- denotes )
T8594 17262-17268 IN denotes during
T8595 17269-17272 NN denotes PMA
T8596 17273-17281 NN denotes exposure
T8597 17282-17290 VB denotes followed
T8598 17291-17293 IN denotes by
T8599 17294-17295 DT denotes a
T8600 17296-17311 NN denotes down-regulation
T8601 17312-17314 TO denotes to
T8602 17315-17318 DT denotes the
T8603 17319-17325 JJ denotes lowest
T8604 17326-17332 NN denotes levels
T8605 17333-17335 IN denotes at
T8606 17336-17337 CD denotes 6
T8607 17338-17339 NN denotes h
T8608 17341-17345 DT denotes This
T8609 17346-17348 VB denotes is
T8610 17349-17351 IN denotes in
T8611 17352-17356 NN denotes line
T8612 17357-17361 IN denotes with
T8613 17362-17366 NNP denotes Park
T8614 17367-17370 CC denotes and
T8615 17371-17381 NN denotes colleagues
T8616 17382-17383 -LRB- denotes [
T8617 17383-17385 CD denotes 36
T8618 17385-17386 -RRB- denotes ]
T8619 17387-17390 WP denotes who
T8620 17391-17403 VB denotes demonstrated
T8621 17404-17405 DT denotes a
T8622 17406-17411 JJ denotes rapid
T8623 17412-17420 NN denotes increase
T8624 17421-17423 IN denotes in
T8625 17424-17429 NN denotes NF-κB
T8626 17430-17438 NN denotes activity
T8627 17439-17448 VB denotes following
T8628 17449-17459 JJ denotes short-term
T8629 17460-17471 NN denotes stimulation
T8630 17472-17476 IN denotes with
T8631 17477-17480 NN denotes PMA
T8632 17480-17481 -COMMA- denotes ,
T8633 17482-17485 CC denotes but
T8634 17486-17495 VB denotes prolonged
T8635 17496-17505 NN denotes challenge
T8636 17506-17514 VB denotes resulted
T8637 17515-17517 IN denotes in
T8638 17518-17519 DT denotes a
T8639 17520-17530 JJ denotes persistent
T8640 17531-17541 NN denotes inhibition
T8641 17542-17544 IN denotes of
T8642 17545-17550 NN denotes NF-κB
T8643 17552-17556 PRP denotes They
T8644 17557-17563 VB denotes showed
T8645 17564-17568 IN denotes that
T8646 17569-17572 DT denotes the
T8647 17573-17583 NN denotes inhibition
T8648 17584-17586 IN denotes of
T8649 17587-17592 NN denotes NF-κB
T8650 17593-17596 VB denotes was
T8651 17597-17600 JJ denotes due
T8652 17601-17603 TO denotes to
T8653 17604-17617 JJ denotes PKC-dependent
T8654 17618-17629 NN denotes degradation
T8655 17630-17632 IN denotes of
T8656 17633-17636 NN denotes IκB
T8657 17637-17643 NN denotes kinase
T8658 17644-17645 NN denotes β
T8659 17646-17649 CC denotes and
T8660 17650-17651 VB denotes γ
T8661 17652-17654 IN denotes in
T8662 17655-17663 NN denotes response
T8663 17664-17666 TO denotes to
T8664 17667-17670 NN denotes PMA
T8665 17672-17685 RB denotes Interestingly
T8666 17685-17686 -COMMA- denotes ,
T8667 17687-17690 DT denotes the
T8668 17691-17693 NN denotes HK
T8669 17694-17696 FW denotes E.
T8670 17697-17701 FW denotes coli
T8671 17702-17710 NN denotes exposure
T8672 17711-17718 VB denotes induced
T8673 17719-17724 NN denotes NF-κB
T8674 17725-17735 NN denotes activation
T8675 17736-17743 IN denotes without
T8676 17744-17753 VB denotes affecting
T8677 17754-17758 NN denotes AP-1
T8678 17759-17767 NN denotes activity
T8679 17769-17773 NNP denotes Wang
T8680 17774-17777 CC denotes and
T8681 17778-17788 NN denotes colleagues
T8682 17789-17790 -LRB- denotes [
T8683 17790-17792 CD denotes 37
T8684 17792-17793 -RRB- denotes ]
T8685 17794-17802 VB denotes reported
T8686 17803-17805 DT denotes an
T8687 17806-17814 JJ denotes elevated
T8688 17815-17827 JJ denotes inflammatory
T8689 17828-17836 NN denotes response
T8690 17837-17839 IN denotes by
T8691 17840-17849 VB denotes obtaining
T8692 17850-17860 NN denotes expression
T8693 17861-17863 IN denotes of
T8694 17864-17868 NN denotes IL-6
T8695 17869-17878 VB denotes following
T8696 17879-17882 DT denotes the
T8697 17883-17891 NN denotes exposure
T8698 17892-17894 IN denotes of
T8699 17895-17902 NN denotes T-cells
T8700 17903-17905 TO denotes to
T8701 17906-17919 NN denotes peptidoglycan
T8702 17921-17930 NN denotes Reduction
T8703 17931-17933 IN denotes in
T8704 17934-17939 NN denotes NF-κB
T8705 17940-17942 IN denotes by
T8706 17943-17950 NN denotes calcium
T8707 17951-17960 NN denotes ionophore
T8708 17961-17970 VB denotes following
T8709 17971-17973 NN denotes HK
T8710 17974-17976 FW denotes E.
T8711 17977-17981 FW denotes coli
T8712 17982-17993 NN denotes stimulation
T8713 17994-17997 MD denotes may
T8714 17998-18000 VB denotes be
T8715 18001-18004 JJ denotes due
T8716 18005-18007 TO denotes to
T8717 18008-18011 DT denotes the
T8718 18012-18016 NN denotes Ca2+
T8719 18017-18024 NN denotes binding
T8720 18025-18032 NN denotes protein
T8721 18033-18043 NN denotes calmodulin
T8722 18044-18045 -LRB- denotes (
T8723 18045-18048 NN denotes CaM
T8724 18048-18049 -RRB- denotes )
T8725 18049-18050 -COMMA- denotes ,
T8726 18051-18056 WDT denotes which
T8727 18057-18060 VB denotes has
T8728 18061-18065 VB denotes been
T8729 18066-18071 VB denotes shown
T8730 18072-18074 TO denotes to
T8731 18075-18085 RB denotes negatively
T8732 18086-18094 VB denotes regulate
T8733 18095-18100 NN denotes c-Rel
T8734 18101-18105 WRB denotes when
T8735 18106-18115 VB denotes activated
T8736 18116-18117 -LRB- denotes [
T8737 18117-18119 CD denotes 38
T8738 18119-18120 -RRB- denotes ]
T8739 18122-18125 DT denotes The
T8740 18126-18136 NN denotes regulation
T8741 18137-18139 IN denotes of
T8742 18140-18145 NN denotes NF-κB
T8743 18146-18149 CC denotes and
T8744 18150-18154 NN denotes AP-1
T8745 18155-18163 VB denotes observed
T8746 18164-18166 IN denotes in
T8747 18167-18170 DT denotes the
T8748 18171-18178 JJ denotes present
T8749 18179-18184 NN denotes study
T8750 18185-18188 VB denotes was
T8751 18189-18191 IN denotes in
T8752 18192-18201 NN denotes agreement
T8753 18202-18206 IN denotes with
T8754 18207-18214 JJ denotes earlier
T8755 18215-18222 NN denotes studies
T8756 18224-18231 NN denotes T-cells
T8757 18232-18239 VB denotes produce
T8758 18240-18241 DT denotes a
T8759 18242-18247 JJ denotes broad
T8760 18248-18253 NN denotes range
T8761 18254-18256 IN denotes of
T8762 18257-18261 JJ denotes pro-
T8763 18262-18265 CC denotes and
T8764 18266-18283 JJ denotes anti-inflammatory
T8765 18284-18293 NN denotes cytokines
T8766 18293-18294 -COMMA- denotes ,
T8767 18295-18304 VB denotes including
T8768 18305-18309 NN denotes IL-2
T8769 18309-18310 -COMMA- denotes ,
T8770 18311-18315 NN denotes IL-6
T8771 18315-18316 -COMMA- denotes ,
T8772 18317-18322 NN denotes CXCL8
T8773 18322-18323 -COMMA- denotes ,
T8774 18324-18327 NN denotes TNF
T8775 18328-18331 CC denotes and
T8776 18332-18337 NN denotes IL-10
T8777 18337-18338 -COMMA- denotes ,
T8778 18339-18341 IN denotes in
T8779 18342-18350 NN denotes response
T8780 18351-18353 TO denotes to
T8781 18354-18364 NN denotes infections
T8782 18365-18367 CC denotes or
T8783 18368-18373 JJ denotes other
T8784 18374-18380 NN denotes stress
T8785 18381-18388 NN denotes factors
T8786 18389-18390 -LRB- denotes [
T8787 18390-18392 CD denotes 39
T8788 18392-18393 -RRB- denotes ]
T8789 18395-18398 DT denotes The
T8790 18399-18409 NN denotes assessment
T8791 18410-18412 IN denotes of
T8792 18413-18419 NN denotes Jurkat
T8793 18420-18426 NN denotes T-cell
T8794 18427-18439 JJ denotes inflammatory
T8795 18440-18449 NN denotes responses
T8796 18450-18451 -LRB- denotes (
T8797 18451-18456 NN denotes Table
T8798 18457-18458 CD denotes 1
T8799 18458-18459 -RRB- denotes )
T8800 18460-18468 VB denotes revealed
T8801 18469-18471 DT denotes an
T8802 18472-18480 VB denotes enhanced
T8803 18481-18485 NN denotes IL-2
T8804 18486-18496 NN denotes expression
T8805 18497-18501 IN denotes upon
T8806 18502-18510 NN denotes exposure
T8807 18511-18513 TO denotes to
T8808 18514-18517 NN denotes PMA
T8809 18518-18520 CC denotes or
T8810 18521-18523 NN denotes HK
T8811 18524-18526 FW denotes E.
T8812 18527-18531 FW denotes coli
T8813 18532-18535 JJ denotes due
T8814 18536-18538 TO denotes to
T8815 18539-18542 NN denotes PKC
T8816 18543-18553 NN denotes activation
T8817 18554-18555 -LRB- denotes [
T8818 18555-18557 CD denotes 40
T8819 18557-18558 -RRB- denotes ]
T8820 18560-18562 IN denotes In
T8821 18563-18571 NN denotes addition
T8822 18572-18574 TO denotes to
T8823 18575-18578 DT denotes the
T8824 18579-18592 NN denotes transcription
T8825 18593-18599 NN denotes factor
T8826 18600-18605 NN denotes NF-κB
T8827 18605-18606 -COMMA- denotes ,
T8828 18607-18611 NN denotes AP-1
T8829 18612-18619 NN denotes binding
T8830 18620-18625 NN denotes sites
T8831 18626-18630 VB denotes have
T8832 18631-18635 VB denotes been
T8833 18636-18646 VB denotes identified
T8834 18647-18649 IN denotes in
T8835 18650-18653 DT denotes the
T8836 18654-18658 NN denotes IL-6
T8837 18659-18667 NN denotes promoter
T8838 18668-18674 NN denotes region
T8839 18674-18675 -COMMA- denotes ,
T8840 18676-18686 VB denotes indicating
T8841 18687-18695 JJ denotes multiple
T8842 18696-18706 NN denotes regulation
T8843 18707-18708 -LRB- denotes [
T8844 18708-18710 CD denotes 22
T8845 18710-18711 -RRB- denotes ]
T8846 18713-18717 NN denotes AP-1
T8847 18718-18721 CC denotes and
T8848 18722-18727 NN denotes NF-κB
T8849 18728-18732 VB denotes have
T8850 18733-18737 RB denotes also
T8851 18738-18742 VB denotes been
T8852 18743-18755 VB denotes demonstrated
T8853 18756-18758 TO denotes to
T8854 18759-18767 VB denotes regulate
T8855 18768-18773 NN denotes CXCL8
T8856 18774-18784 NN denotes expression
T8857 18785-18791 IN denotes during
T8858 18792-18801 NN denotes induction
T8859 18802-18804 IN denotes of
T8860 18805-18817 JJ denotes inflammatory
T8861 18818-18827 NN denotes responses
T8862 18828-18830 IN denotes in
T8863 18831-18838 NN denotes T-cells
T8864 18839-18840 -LRB- denotes [
T8865 18840-18842 CD denotes 12
T8866 18842-18843 -RRB- denotes ]
T8867 18845-18856 RB denotes Furthermore
T8868 18856-18857 -COMMA- denotes ,
T8869 18858-18862 NN denotes IL-6
T8870 18863-18866 CC denotes and
T8871 18867-18872 NN denotes CXCL8
T8872 18873-18888 NN denotes gene-expression
T8873 18889-18891 VB denotes is
T8874 18892-18902 VB denotes associated
T8875 18903-18907 IN denotes with
T8876 18908-18910 DT denotes an
T8877 18911-18916 JJ denotes early
T8878 18917-18923 JJ denotes immune
T8879 18924-18932 NN denotes response
T8880 18933-18935 IN denotes in
T8881 18936-18942 NN denotes Jurkat
T8882 18943-18950 NN denotes T-cells
T8883 18951-18952 -LRB- denotes [
T8884 18952-18954 CD denotes 41
T8885 18954-18955 -RRB- denotes ]
T8886 18957-18959 IN denotes In
T8887 18960-18963 DT denotes the
T8888 18964-18971 JJ denotes present
T8889 18972-18977 NN denotes study
T8890 18977-18978 -COMMA- denotes ,
T8891 18979-18983 CC denotes both
T8892 18984-18987 NN denotes PMA
T8893 18988-18991 CC denotes and
T8894 18992-18994 NN denotes HK
T8895 18995-18997 NNP denotes E.
T8896 18998-19002 FW denotes coli
T8897 19003-19011 VB denotes resulted
T8898 19012-19014 IN denotes in
T8899 19015-19025 JJ denotes comparable
T8900 19026-19035 NN denotes increases
T8901 19036-19038 IN denotes in
T8902 19039-19043 NN denotes IL-6
T8903 19044-19049 IN denotes while
T8904 19050-19053 NN denotes PMA
T8905 19054-19057 VB denotes was
T8906 19058-19062 RB denotes more
T8907 19063-19069 JJ denotes potent
T8908 19070-19072 IN denotes at
T8909 19073-19083 VB denotes activating
T8910 19084-19089 NN denotes CXCL8
T8911 19090-19097 NN denotes release
T8912 19099-19102 NN denotes PMA
T8913 19103-19106 CC denotes and
T8914 19107-19109 NN denotes HK
T8915 19110-19112 FW denotes E.
T8916 19113-19117 FW denotes coli
T8917 19118-19127 NN denotes treatment
T8918 19128-19132 RB denotes also
T8919 19133-19140 VB denotes induced
T8920 19141-19144 NN denotes TNF
T8921 19145-19155 NN denotes expression
T8922 19157-19160 NN denotes TNF
T8923 19161-19163 VB denotes is
T8924 19164-19167 CD denotes one
T8925 19168-19170 IN denotes of
T8926 19171-19174 DT denotes the
T8927 19175-19180 JJ denotes first
T8928 19181-19190 NN denotes cytokines
T8929 19191-19198 VB denotes induced
T8930 19199-19201 IN denotes by
T8931 19202-19209 NN denotes T-cells
T8932 19210-19211 -LRB- denotes [
T8933 19211-19213 CD denotes 42
T8934 19213-19214 -RRB- denotes ]
T8935 19215-19218 CC denotes and
T8936 19219-19222 PRP-DOLLAR- denotes its
T8937 19223-19233 NN denotes expression
T8938 19234-19236 VB denotes is
T8939 19237-19246 VB denotes regulated
T8940 19247-19249 IN denotes by
T8941 19250-19261 NN denotes calcineurin
T8942 19261-19262 -COMMA- denotes ,
T8943 19263-19267 NN denotes NFAT
T8944 19268-19271 CC denotes and
T8945 19272-19281 NN denotes ATF-2/Jun
T8946 19282-19283 -LRB- denotes [
T8947 19283-19285 CD denotes 20
T8948 19285-19286 -RRB- denotes ]
T8949 19288-19295 RB denotes However
T8950 19295-19296 -COMMA- denotes ,
T8951 19297-19311 JJ denotes PMA-stimulated
T8952 19312-19318 NN denotes Jurkat
T8953 19319-19326 NN denotes T-cells
T8954 19327-19333 VB denotes showed
T8955 19334-19336 DT denotes no
T8956 19337-19347 NN denotes difference
T8957 19348-19350 IN denotes in
T8958 19351-19356 NN denotes IL-10
T8959 19357-19367 NN denotes expression
T8960 19368-19378 VB denotes indicating
T8961 19379-19381 DT denotes an
T8962 19382-19389 VB denotes induced
T8963 19390-19402 JJ denotes inflammatory
T8964 19403-19411 NN denotes response
T8965 19413-19415 NN denotes HK
T8966 19416-19418 FW denotes E.
T8967 19419-19423 FW denotes coli
T8968 19424-19433 NN denotes treatment
T8969 19434-19442 VB denotes resulted
T8970 19443-19445 IN denotes in
T8971 19446-19447 DT denotes a
T8972 19448-19459 JJ denotes significant
T8973 19460-19469 NN denotes reduction
T8974 19470-19472 IN denotes of
T8975 19473-19478 NN denotes IL-10
T8976 19479-19489 NN denotes expression
T8977 19491-19494 DT denotes The
T8978 19495-19512 JJ denotes anti-inflammatory
T8979 19513-19521 NN denotes cytokine
T8980 19522-19527 NN denotes IL-10
T8981 19528-19530 VB denotes is
T8982 19531-19536 VB denotes known
T8983 19537-19539 TO denotes to
T8984 19540-19547 VB denotes inhibit
T8985 19548-19554 NN denotes T-cell
T8986 19555-19565 NN denotes activation
T8987 19565-19566 -COMMA- denotes ,
T8988 19567-19580 NN denotes proliferation
T8989 19581-19584 CC denotes and
T8990 19585-19588 DT denotes the
T8991 19589-19599 NN denotes expression
T8992 19600-19602 IN denotes of
T8993 19603-19619 JJ denotes pro-inflammatory
T8994 19620-19629 NN denotes cytokines
T8995 19629-19630 -COMMA- denotes ,
T8996 19631-19635 JJ denotes such
T8997 19636-19638 IN denotes as
T8998 19639-19643 NN denotes IL-2
T8999 19643-19644 -COMMA- denotes ,
T9000 19645-19649 NN denotes IL-5
T9001 19650-19653 CC denotes and
T9002 19654-19659 NN denotes INF-γ
T9003 19660-19661 -LRB- denotes [
T9004 19661-19666 CD denotes 39,43
T9005 19666-19667 -RRB- denotes ]
T9006 19668-19671 CC denotes and
T9007 19672-19680 VB denotes regulate
T9008 19681-19693 JJ denotes inflammatory
T9009 19694-19703 NN denotes responses
T9010 19704-19706 IN denotes by
T9011 19707-19715 VB denotes inducing
T9012 19716-19722 NN denotes T-cell
T9013 19723-19729 NN denotes anergy
T9014 19730-19731 -LRB- denotes [
T9015 19731-19733 CD denotes 44
T9016 19733-19734 -RRB- denotes ]
T9017 19736-19739 DT denotes The
T9018 19740-19744 NN denotes time
T9019 19745-19751 NN denotes course
T9020 19752-19760 NN denotes analysis
T9021 19761-19763 IN denotes of
T9022 19764-19772 NN denotes cytokine
T9023 19773-19783 NN denotes expression
T9024 19784-19790 VB denotes showed
T9025 19791-19792 DT denotes a
T9026 19793-19804 NN denotes correlation
T9027 19805-19812 IN denotes between
T9028 19813-19817 NN denotes AP-1
T9029 19818-19821 CC denotes and
T9030 19822-19825 DT denotes the
T9031 19826-19835 NN denotes chemokine
T9032 19836-19841 NN denotes CXCL8
T9033 19842-19847 WRB denotes where
T9034 19848-19853 NN denotes CXCL8
T9035 19854-19864 NN denotes expression
T9036 19865-19868 VB denotes was
T9037 19869-19882 RB denotes significantly
T9038 19883-19891 VB denotes elevated
T9039 19892-19899 RB denotes already
T9040 19900-19902 IN denotes at
T9041 19903-19906 CD denotes 2-6
T9042 19907-19908 NN denotes h
T9043 19909-19914 IN denotes after
T9044 19915-19918 NN denotes PMA
T9045 19919-19927 NN denotes exposure
T9046 19929-19932 DT denotes The
T9047 19933-19938 NN denotes CXCL8
T9048 19939-19949 NN denotes expression
T9049 19950-19953 VB denotes did
T9050 19954-19957 RB denotes not
T9051 19958-19967 VB denotes correlate
T9052 19968-19972 IN denotes with
T9053 19973-19976 DT denotes the
T9054 19977-19982 JJ denotes early
T9055 19983-19988 NN denotes NF-κB
T9056 19989-19999 NN denotes activation
T9057 20000-20001 -LRB- denotes (
T9058 20001-20002 CD denotes 1
T9059 20003-20006 NN denotes min
T9060 20006-20007 -RRB- denotes )
T9061 20008-20010 CC denotes or
T9062 20011-20015 IN denotes with
T9063 20016-20019 DT denotes the
T9064 20020-20035 NN denotes down-regulation
T9065 20036-20038 IN denotes of
T9066 20039-20044 NN denotes NF-κB
T9067 20045-20047 IN denotes at
T9068 20048-20049 CD denotes 2
T9069 20050-20051 NN denotes h
T9070 20052-20056 NN denotes post
T9071 20057-20065 NN denotes exposure
T9072 20067-20071 CC denotes Both
T9073 20072-20076 NN denotes IL-6
T9074 20077-20080 CC denotes and
T9075 20081-20084 NN denotes TNF
T9076 20085-20095 NN denotes expression
T9077 20096-20100 VB denotes were
T9078 20101-20103 RB denotes up
T9079 20104-20113 VB denotes regulated
T9080 20114-20121 IN denotes between
T9081 20122-20126 CD denotes 6-24
T9082 20127-20128 NN denotes h
T9083 20130-20136 IN denotes During
T9084 20137-20141 DT denotes this
T9085 20142-20148 NN denotes period
T9086 20148-20149 -COMMA- denotes ,
T9087 20150-20155 NN denotes NF-κB
T9088 20156-20165 VB denotes increased
T9089 20166-20170 IN denotes from
T9090 20171-20174 PRP-DOLLAR- denotes its
T9091 20175-20182 JJ denotes minimum
T9092 20183-20188 NN denotes level
T9093 20189-20191 IN denotes at
T9094 20192-20193 CD denotes 6
T9095 20194-20195 NN denotes h
T9096 20197-20200 NN denotes PKC
T9097 20201-20204 VB denotes has
T9098 20205-20209 VB denotes been
T9099 20210-20215 VB denotes shown
T9100 20216-20218 TO denotes to
T9101 20219-20221 VB denotes be
T9102 20222-20232 VB denotes associated
T9103 20233-20237 IN denotes with
T9104 20238-20241 DT denotes the
T9105 20242-20252 NN denotes activation
T9106 20253-20255 IN denotes of
T9107 20256-20260 NN denotes AP-1
T9108 20260-20261 -COMMA- denotes ,
T9109 20262-20265 CC denotes but
T9110 20266-20269 RB denotes not
T9111 20270-20274 IN denotes with
T9112 20275-20280 NN denotes NF-κB
T9113 20281-20291 NN denotes activation
T9114 20292-20294 IN denotes of
T9115 20295-20298 DT denotes the
T9116 20299-20303 NN denotes IL-2
T9117 20304-20312 NN denotes promoter
T9118 20313-20314 -LRB- denotes [
T9119 20314-20316 CD denotes 45
T9120 20316-20317 -RRB- denotes ]
T9121 20319-20327 NN denotes Mutation
T9122 20328-20330 IN denotes of
T9123 20331-20334 DT denotes the
T9124 20335-20340 NN denotes NF-κB
T9125 20341-20345 NN denotes site
T9126 20346-20349 VB denotes did
T9127 20350-20353 RB denotes not
T9128 20354-20360 VB denotes affect
T9129 20361-20365 NN denotes IL-2
T9130 20366-20376 NN denotes expression
T9131 20376-20377 -COMMA- denotes ,
T9132 20378-20385 IN denotes whereas
T9133 20386-20394 NN denotes mutation
T9134 20395-20397 IN denotes of
T9135 20398-20401 DT denotes the
T9136 20402-20406 NN denotes AP-1
T9137 20407-20411 NN denotes site
T9138 20412-20414 CC denotes or
T9139 20415-20418 NN denotes PKC
T9140 20419-20428 NN denotes depletion
T9141 20429-20435 RB denotes almost
T9142 20436-20443 VB denotes revoked
T9143 20444-20448 NN denotes IL-2
T9144 20449-20456 NN denotes release
T9145 20458-20463 DT denotes These
T9146 20464-20476 NN denotes observations
T9147 20477-20485 VB denotes indicate
T9148 20486-20490 IN denotes that
T9149 20491-20494 DT denotes the
T9150 20495-20499 NN denotes MAPK
T9151 20500-20507 NN denotes pathway
T9152 20508-20511 CC denotes and
T9153 20512-20515 DT denotes the
T9154 20516-20529 NN denotes transcription
T9155 20530-20536 NN denotes factor
T9156 20537-20541 NN denotes AP-1
T9157 20542-20546 VB denotes play
T9158 20547-20549 DT denotes an
T9159 20550-20559 JJ denotes important
T9160 20560-20564 NN denotes role
T9161 20565-20567 IN denotes in
T9162 20568-20571 DT denotes the
T9163 20572-20581 NN denotes induction
T9164 20582-20584 IN denotes of
T9165 20585-20597 JJ denotes inflammatory
T9166 20598-20607 NN denotes responses
T9167 20608-20610 IN denotes in
T9168 20611-20617 NN denotes Jurkat
T9169 20618-20625 NN denotes T-cells
T9170 20626-20627 -LRB- denotes [
T9171 20627-20635 CD denotes 12,20,22
T9172 20635-20636 -RRB- denotes ]
T9173 20638-20641 DT denotes The
T9174 20642-20650 VB denotes obtained
T9175 20651-20658 NN denotes results
T9176 20659-20666 VB denotes signify
T9177 20667-20671 IN denotes that
T9178 20672-20677 NN denotes CXCL8
T9179 20678-20681 VB denotes was
T9180 20682-20691 RB denotes primarily
T9181 20692-20701 VB denotes regulated
T9182 20702-20709 IN denotes through
T9183 20710-20713 DT denotes the
T9184 20714-20718 NN denotes MAPK
T9185 20719-20726 NN denotes pathway
T9186 20728-20731 DT denotes The
T9187 20732-20737 NN denotes NF-κB
T9188 20738-20748 NN denotes activation
T9189 20749-20758 NN denotes inhibitor
T9190 20759-20760 -LRB- denotes (
T9191 20760-20763 NN denotes NAI
T9192 20763-20764 -RRB- denotes )
T9193 20765-20771 VB denotes showed
T9194 20772-20783 NN denotes specificity
T9195 20784-20791 IN denotes against
T9196 20792-20797 NN denotes NF-κB
T9197 20798-20801 CC denotes and
T9198 20802-20810 VB denotes resulted
T9199 20811-20813 IN denotes in
T9200 20814-20815 DT denotes a
T9201 20816-20824 JJ denotes complete
T9202 20825-20829 NN denotes IL-6
T9203 20830-20840 NN denotes inhibition
T9204 20841-20850 VB denotes following
T9205 20851-20860 NN denotes induction
T9206 20861-20865 IN denotes with
T9207 20866-20869 NN denotes PMA
T9208 20870-20873 CC denotes and
T9209 20874-20885 JJ denotes significant
T9210 20886-20890 NN denotes IL-6
T9211 20891-20900 NN denotes reduction
T9212 20901-20906 IN denotes after
T9213 20907-20909 NN denotes HK
T9214 20910-20912 FW denotes E.
T9215 20913-20917 FW denotes coli
T9216 20918-20927 NN denotes treatment
T9217 20929-20934 NN denotes CXCL8
T9218 20935-20938 VB denotes was
T9219 20939-20945 RB denotes highly
T9220 20946-20948 RB denotes up
T9221 20949-20958 VB denotes regulated
T9222 20959-20961 IN denotes by
T9223 20962-20965 NN denotes PMA
T9224 20966-20969 CC denotes and
T9225 20970-20973 DT denotes the
T9226 20974-20982 NN denotes addition
T9227 20983-20985 IN denotes of
T9228 20986-20989 NN denotes NAI
T9229 20990-20998 VB denotes resulted
T9230 20999-21001 IN denotes in
T9231 21002-21003 DT denotes a
T9232 21004-21009 JJ denotes minor
T9233 21010-21019 NN denotes reduction
T9234 21020-21022 IN denotes in
T9235 21023-21028 NN denotes CXCL8
T9236 21029-21039 NN denotes expression
T9237 21041-21052 RB denotes Furthermore
T9238 21052-21053 -COMMA- denotes ,
T9239 21054-21059 NN denotes CXCL8
T9240 21060-21070 NN denotes expression
T9241 21071-21074 VB denotes was
T9242 21075-21078 RB denotes not
T9243 21079-21087 VB denotes affected
T9244 21088-21090 IN denotes by
T9245 21091-21094 NN denotes NAI
T9246 21095-21104 VB denotes following
T9247 21105-21107 NN denotes HK
T9248 21108-21110 FW denotes E.
T9249 21111-21115 FW denotes coli
T9250 21116-21125 NN denotes treatment
T9251 21125-21126 -COMMA- denotes ,
T9252 21127-21137 VB denotes indicating
T9253 21138-21139 DT denotes a
T9254 21140-21144 NN denotes lack
T9255 21145-21147 IN denotes of
T9256 21148-21159 NN denotes correlation
T9257 21160-21167 IN denotes between
T9258 21168-21173 NN denotes CXCL8
T9259 21174-21177 CC denotes and
T9260 21178-21183 NN denotes NF-κB
T9261 21185-21192 JJ denotes Further
T9262 21193-21201 NN denotes analysis
T9263 21202-21204 IN denotes of
T9264 21205-21210 NN denotes CXCL8
T9265 21211-21221 NN denotes expression
T9266 21222-21230 VB denotes revealed
T9267 21231-21232 DT denotes a
T9268 21233-21248 NN denotes down-regulation
T9269 21249-21251 IN denotes by
T9270 21252-21256 NN denotes PKC-
T9271 21257-21260 CC denotes and
T9272 21261-21265 NN denotes JNK-
T9273 21266-21276 NN denotes inhibitors
T9274 21276-21277 -COMMA- denotes ,
T9275 21278-21288 VB denotes suggesting
T9276 21289-21291 DT denotes an
T9277 21292-21303 NN denotes involvement
T9278 21304-21306 IN denotes of
T9279 21307-21311 NN denotes AP-1
T9280 21312-21315 IN denotes via
T9281 21316-21319 NN denotes PKC
T9282 21320-21323 CC denotes and
T9283 21324-21327 NN denotes JNK
T9284 21327-21328 -COMMA- denotes ,
T9285 21329-21341 RB denotes respectively
T9286 21343-21351 NN denotes Analysis
T9287 21352-21354 IN denotes of
T9288 21355-21359 NN denotes gene
T9289 21360-21370 NN denotes expression
T9290 21371-21378 RB denotes further
T9291 21379-21388 VB denotes confirmed
T9292 21389-21393 IN denotes that
T9293 21394-21398 NN denotes il-6
T9294 21399-21402 CC denotes and
T9295 21403-21408 NN denotes cxcl8
T9296 21409-21413 VB denotes were
T9297 21414-21425 VB denotes upregulated
T9298 21426-21428 IN denotes by
T9299 21429-21432 NN denotes PMA
T9300 21434-21444 NN denotes Expression
T9301 21445-21447 IN denotes of
T9302 21448-21452 NN denotes il-6
T9303 21453-21460 VB denotes dropped
T9304 21461-21466 IN denotes below
T9305 21467-21472 JJ denotes basal
T9306 21473-21479 NN denotes levels
T9307 21480-21489 VB denotes following
T9308 21490-21500 NN denotes inhibition
T9309 21501-21503 IN denotes of
T9310 21504-21509 NN denotes NF-κB
T9311 21510-21513 CC denotes and
T9312 21514-21517 NN denotes JNK
T9313 21518-21525 IN denotes whereas
T9314 21526-21531 NN denotes cxcl8
T9315 21532-21540 VB denotes remained
T9316 21541-21549 JJ denotes elevated
T9317 21550-21555 IN denotes above
T9318 21556-21561 JJ denotes basal
T9319 21562-21568 NN denotes levels
T9320 21569-21570 -LRB- denotes (
T9321 21570-21579 RB denotes 16.5-fold
T9322 21580-21583 CC denotes and
T9323 21584-21592 JJ denotes 7.1-fold
T9324 21593-21605 RB denotes respectively
T9325 21605-21606 -RRB- denotes )
T9326 21607-21616 VB denotes following
T9327 21617-21620 DT denotes the
T9328 21621-21625 JJ denotes same
T9329 21626-21635 NN denotes treatment
T9330 21637-21648 RB denotes Furthermore
T9331 21648-21649 -COMMA- denotes ,
T9332 21650-21660 NN denotes inhibition
T9333 21661-21663 IN denotes of
T9334 21664-21667 NN denotes PKC
T9335 21668-21671 VB denotes did
T9336 21672-21675 RB denotes not
T9337 21676-21682 VB denotes result
T9338 21683-21685 IN denotes in
T9339 21686-21687 DT denotes a
T9340 21688-21699 JJ denotes significant
T9341 21700-21708 NN denotes decrease
T9342 21709-21711 IN denotes of
T9343 21712-21716 NN denotes il-6
T9344 21717-21719 CC denotes or
T9345 21720-21725 NN denotes cxcl8
T9346 21725-21726 -COMMA- denotes ,
T9347 21727-21732 WDT denotes which
T9348 21733-21735 VB denotes is
T9349 21736-21738 IN denotes in
T9350 21739-21749 NN denotes accordance
T9351 21750-21754 IN denotes with
T9352 21755-21762 NN denotes protein
T9353 21763-21767 NN denotes data
T9354 21768-21769 -LRB- denotes (
T9355 21769-21775 NN denotes figure
T9356 21776-21777 CD denotes 6
T9357 21777-21778 -RRB- denotes )
T9358 21780-21785 DT denotes These
T9359 21786-21793 NN denotes results
T9360 21794-21801 VB denotes suggest
T9361 21802-21806 IN denotes that
T9362 21807-21812 NN denotes NF-κB
T9363 21813-21815 VB denotes is
T9364 21816-21824 VB denotes involved
T9365 21825-21827 IN denotes in
T9366 21828-21832 NN denotes IL-6
T9367 21833-21843 NN denotes regulation
T9368 21844-21847 CC denotes and
T9369 21848-21855 NN denotes release
T9370 21856-21861 IN denotes while
T9371 21862-21864 PRP denotes it
T9372 21865-21867 VB denotes is
T9373 21868-21871 RB denotes not
T9374 21872-21880 VB denotes required
T9375 21881-21884 IN denotes for
T9376 21885-21888 DT denotes the
T9377 21889-21899 NN denotes expression
T9378 21900-21902 IN denotes of
T9379 21903-21908 NN denotes CXCL8
T9380 21909-21911 IN denotes in
T9381 21912-21918 NN denotes Jurkat
T9382 21919-21920 NN denotes T
T9383 21921-21926 NN denotes cells
T9384 21928-21931 DT denotes The
T9385 21932-21945 NN denotes transcription
T9386 21946-21952 NN denotes factor
T9387 21953-21958 NN denotes NF-κB
T9388 21959-21961 VB denotes is
T9389 21962-21973 JJ denotes responsible
T9390 21974-21977 IN denotes for
T9391 21978-21979 DT denotes a
T9392 21980-21985 JJ denotes rapid
T9393 21986-21992 JJ denotes immune
T9394 21993-22001 NN denotes response
T9395 22002-22007 WDT denotes which
T9396 22008-22010 VB denotes is
T9397 22011-22019 VB denotes followed
T9398 22020-22022 IN denotes by
T9399 22023-22025 DT denotes an
T9400 22026-22034 NN denotes increase
T9401 22035-22037 IN denotes in
T9402 22038-22051 NN denotes transcription
T9403 22052-22054 IN denotes of
T9404 22055-22058 NN denotes IκB
T9405 22059-22063 RB denotes thus
T9406 22064-22074 VB denotes inhibiting
T9407 22075-22080 NN denotes NF-κB
T9408 22081-22082 -LRB- denotes [
T9409 22082-22084 CD denotes 46
T9410 22084-22085 -RRB- denotes ]
T9411 22087-22097 NN denotes Activation
T9412 22098-22100 IN denotes of
T9413 22101-22106 NN denotes NF-κB
T9414 22107-22109 IN denotes in
T9415 22110-22116 NN denotes Jurkat
T9416 22117-22124 NN denotes T-cells
T9417 22125-22127 VB denotes is
T9418 22128-22137 JJ denotes dependent
T9419 22138-22140 IN denotes on
T9420 22141-22146 NN denotes Bcl10
T9421 22147-22157 NN denotes activation
T9422 22157-22158 -COMMA- denotes ,
T9423 22159-22164 WDT denotes which
T9424 22165-22167 IN denotes in
T9425 22168-22172 NN denotes turn
T9426 22173-22175 VB denotes is
T9427 22176-22185 VB denotes regulated
T9428 22186-22188 IN denotes by
T9429 22189-22192 NN denotes PKC
T9430 22194-22200 JJ denotes Recent
T9431 22201-22208 NN denotes studies
T9432 22209-22213 VB denotes have
T9433 22214-22225 VB denotes established
T9434 22226-22229 DT denotes the
T9435 22230-22240 NN denotes importance
T9436 22241-22243 IN denotes of
T9437 22244-22245 DT denotes a
T9438 22246-22253 NN denotes protein
T9439 22254-22261 NN denotes complex
T9440 22262-22272 VB denotes consisting
T9441 22273-22275 IN denotes of
T9442 22276-22282 NN denotes CARMA1
T9443 22282-22283 -COMMA- denotes ,
T9444 22284-22289 NN denotes Bcl10
T9445 22290-22293 CC denotes and
T9446 22294-22299 NN denotes MALT1
T9447 22300-22301 -LRB- denotes (
T9448 22301-22304 NN denotes CBM
T9449 22304-22305 -RRB- denotes )
T9450 22305-22306 -COMMA- denotes ,
T9451 22307-22309 IN denotes in
T9452 22310-22313 DT denotes the
T9453 22314-22323 NN denotes induction
T9454 22324-22326 IN denotes of
T9455 22327-22332 NN denotes NF-κB
T9456 22334-22347 VB denotes Investigating
T9457 22348-22353 NN denotes Bcl10
T9458 22353-22354 -COMMA- denotes ,
T9459 22355-22367 NNP denotes Scharschmidt
T9460 22368-22371 CC denotes and
T9461 22372-22382 NN denotes colleagues
T9462 22383-22384 -LRB- denotes [
T9463 22384-22386 CD denotes 47
T9464 22386-22387 -RRB- denotes ]
T9465 22388-22400 VB denotes demonstrated
T9466 22401-22405 IN denotes that
T9467 22406-22408 PRP denotes it
T9468 22409-22411 VB denotes is
T9469 22412-22413 DT denotes a
T9470 22414-22422 JJ denotes critical
T9471 22423-22432 NN denotes regulator
T9472 22433-22435 IN denotes of
T9473 22436-22441 NN denotes NF-κB
T9474 22442-22450 NN denotes activity
T9475 22452-22467 NN denotes Down-regulation
T9476 22468-22470 IN denotes of
T9477 22471-22476 NN denotes Bcl10
T9478 22477-22481 IN denotes from
T9479 22482-22489 NN denotes signals
T9480 22490-22500 VB denotes transduced
T9481 22501-22504 IN denotes via
T9482 22505-22508 DT denotes the
T9483 22509-22517 NN denotes TCR/CD28
T9484 22518-22521 CC denotes and
T9485 22522-22525 NN denotes PKC
T9486 22526-22534 VB denotes resulted
T9487 22535-22537 IN denotes in
T9488 22538-22539 DT denotes a
T9489 22540-22551 JJ denotes concomitant
T9490 22552-22567 NN denotes down-regulation
T9491 22568-22570 IN denotes of
T9492 22571-22576 NN denotes NF-κB
T9493 22578-22582 PRP denotes They
T9494 22583-22592 VB denotes suggested
T9495 22593-22597 IN denotes that
T9496 22598-22603 NN denotes Bcl10
T9497 22604-22606 VB denotes is
T9498 22607-22616 RB denotes initially
T9499 22617-22626 VB denotes activated
T9500 22627-22629 IN denotes by
T9501 22630-22637 NN denotes TCR/PKC
T9502 22638-22641 CC denotes but
T9503 22642-22646 IN denotes that
T9504 22647-22656 JJ denotes continued
T9505 22657-22667 NN denotes activation
T9506 22668-22669 -LRB- denotes (
T9507 22669-22670 SYM denotes >
T9508 22670-22671 CD denotes 1
T9509 22672-22673 NN denotes h
T9510 22673-22674 -RRB- denotes )
T9511 22675-22683 VB denotes promotes
T9512 22684-22687 PRP-DOLLAR- denotes its
T9513 22688-22699 NN denotes degradation
T9514 22701-22708 NN denotes Narayan
T9515 22709-22712 CC denotes and
T9516 22713-22723 NN denotes colleagues
T9517 22724-22725 -LRB- denotes [
T9518 22725-22727 CD denotes 27
T9519 22727-22728 -RRB- denotes ]
T9520 22729-22738 VB denotes suggested
T9521 22739-22743 IN denotes that
T9522 22744-22752 NN denotes deletion
T9523 22753-22755 IN denotes in
T9524 22756-22759 DT denotes any
T9525 22760-22762 IN denotes of
T9526 22763-22766 DT denotes the
T9527 22767-22772 CD denotes three
T9528 22773-22776 NN denotes CBM
T9529 22777-22784 NN denotes complex
T9530 22785-22793 NN denotes proteins
T9531 22794-22801 VB denotes impairs
T9532 22802-22818 JJ denotes antigen-receptor
T9533 22819-22828 JJ denotes dependent
T9534 22829-22839 NN denotes activation
T9535 22840-22842 IN denotes of
T9536 22843-22848 NN denotes NF-κB
T9537 22850-22854 PRP denotes They
T9538 22855-22861 VB denotes showed
T9539 22862-22866 IN denotes that
T9540 22867-22872 NN denotes NF-κB
T9541 22873-22883 NN denotes activation
T9542 22884-22887 IN denotes via
T9543 22888-22891 NN denotes Akt
T9544 22892-22900 VB denotes requires
T9545 22901-22907 NN denotes CARMA1
T9546 22908-22911 CC denotes and
T9547 22912-22916 VB denotes acts
T9548 22917-22919 IN denotes in
T9549 22920-22931 NN denotes cooperation
T9550 22932-22936 IN denotes with
T9551 22937-22940 NN denotes PKC
T9552 22941-22950 VB denotes following
T9553 22951-22961 JJ denotes short-term
T9554 22962-22970 NN denotes exposure
T9555 22971-22972 -LRB- denotes (
T9556 22972-22974 CD denotes 30
T9557 22975-22978 NN denotes min
T9558 22978-22979 -RRB- denotes )
T9559 22980-22982 IN denotes of
T9560 22983-22989 NN denotes Jurkat
T9561 22990-22997 NN denotes T-cells
T9562 22998-23002 IN denotes with
T9563 23003-23006 NN denotes PMA
T9564 23008-23011 NN denotes Akt
T9565 23012-23026 VB denotes phosphorylates
T9566 23027-23030 CC denotes and
T9567 23031-23035 RB denotes thus
T9568 23036-23045 VB denotes activates
T9569 23046-23051 NN denotes Bcl10
T9570 23053-23058 DT denotes These
T9571 23059-23066 NN denotes studies
T9572 23067-23075 VB denotes indicate
T9573 23076-23080 IN denotes that
T9574 23081-23084 NN denotes PKC
T9575 23085-23087 VB denotes is
T9576 23088-23095 JJ denotes crucial
T9577 23096-23099 IN denotes for
T9578 23100-23105 NN denotes NF-κB
T9579 23106-23116 NN denotes activation
T9580 23117-23126 VB denotes following
T9581 23127-23137 JJ denotes short-term
T9582 23138-23147 NN denotes treatment
T9583 23148-23155 IN denotes through
T9584 23156-23163 NN denotes signals
T9585 23164-23167 IN denotes via
T9586 23168-23176 NN denotes membrane
T9587 23177-23182 VB denotes bound
T9588 23183-23192 NN denotes receptors
T9589 23193-23197 JJ denotes such
T9590 23198-23200 IN denotes as
T9591 23201-23204 DT denotes the
T9592 23205-23208 NN denotes TCR
T9593 23209-23212 CC denotes and
T9594 23213-23216 DT denotes the
T9595 23217-23231 JJ denotes co-stimulatory
T9596 23232-23240 NN denotes receptor
T9597 23241-23245 NN denotes CD28
T9598 23247-23251 RB denotes Thus
T9599 23251-23252 -COMMA- denotes ,
T9600 23253-23256 DT denotes the
T9601 23257-23260 NN denotes CBM
T9602 23261-23268 NN denotes complex
T9603 23269-23277 NN denotes proteins
T9604 23278-23282 VB denotes play
T9605 23283-23284 DT denotes a
T9606 23285-23288 JJ denotes key
T9607 23289-23293 NN denotes role
T9608 23294-23296 IN denotes in
T9609 23297-23301 DT denotes this
T9610 23302-23312 NN denotes signalling
T9611 23313-23320 NN denotes process
T9612 23322-23325 NN denotes PMA
T9613 23326-23334 VB denotes diffuses
T9614 23335-23339 IN denotes into
T9615 23340-23343 DT denotes the
T9616 23344-23351 NN denotes cytosol
T9617 23352-23355 CC denotes and
T9618 23356-23364 RB denotes directly
T9619 23365-23374 VB denotes activates
T9620 23375-23378 NN denotes PKC
T9621 23379-23384 IN denotes since
T9622 23385-23387 PRP denotes it
T9623 23388-23390 VB denotes is
T9624 23391-23393 DT denotes an
T9625 23394-23402 NN denotes analogue
T9626 23403-23405 TO denotes to
T9627 23406-23420 NN denotes diacylglycerol
T9628 23421-23422 -LRB- denotes [
T9629 23422-23424 CD denotes 48
T9630 23424-23425 -RRB- denotes ]
T9631 23427-23434 JJ denotes Several
T9632 23435-23442 NN denotes studies
T9633 23443-23447 VB denotes have
T9634 23448-23460 VB denotes demonstrated
T9635 23461-23465 IN denotes that
T9636 23466-23476 NN denotes inhibition
T9637 23477-23479 IN denotes of
T9638 23480-23483 NN denotes PKC
T9639 23484-23490 VB denotes blocks
T9640 23491-23496 NN denotes NF-κB
T9641 23497-23500 CC denotes and
T9642 23501-23505 NN denotes AP-1
T9643 23506-23514 NN denotes activity
T9644 23514-23515 -COMMA- denotes ,
T9645 23516-23526 VB denotes suggesting
T9646 23527-23528 DT denotes a
T9647 23529-23535 JJ denotes direct
T9648 23536-23546 NN denotes regulation
T9649 23547-23549 IN denotes of
T9650 23550-23555 DT denotes these
T9651 23556-23569 NN denotes transcription
T9652 23570-23577 NN denotes factors
T9653 23578-23580 IN denotes by
T9654 23581-23584 NN denotes PKC
T9655 23585-23586 -LRB- denotes [
T9656 23586-23591 CD denotes 49,50
T9657 23591-23592 -RRB- denotes ]
T9658 23594-23597 NN denotes PKC
T9659 23598-23600 VB denotes is
T9660 23601-23610 VB denotes activated
T9661 23611-23613 IN denotes at
T9662 23614-23616 DT denotes an
T9663 23617-23622 JJ denotes early
T9664 23623-23628 NN denotes stage
T9665 23629-23638 VB denotes following
T9666 23639-23645 NN denotes T-cell
T9667 23646-23657 NN denotes stimulation
T9668 23658-23661 CC denotes and
T9669 23662-23664 VB denotes is
T9670 23665-23674 RB denotes therefore
T9671 23675-23677 DT denotes an
T9672 23678-23687 JJ denotes important
T9673 23688-23697 NN denotes regulator
T9674 23698-23700 IN denotes of
T9675 23701-23711 JJ denotes downstream
T9676 23712-23724 JJ denotes inflammatory
T9677 23725-23735 NN denotes signalling
T9678 23736-23744 NN denotes pathways
T9679 23745-23752 VB denotes leading
T9680 23753-23755 TO denotes to
T9681 23756-23764 NN denotes cytokine
T9682 23765-23775 NN denotes expression
T9683 23776-23777 -LRB- denotes [
T9684 23777-23779 CD denotes 50
T9685 23779-23780 -RRB- denotes ]
T9686 23782-23784 PRP denotes We
T9687 23785-23789 VB denotes have
T9688 23790-23795 VB denotes shown
T9689 23796-23800 IN denotes that
T9690 23801-23819 NN denotes phosphorylated-PKC
T9691 23820-23822 VB denotes is
T9692 23823-23825 RB denotes up
T9693 23826-23835 VB denotes regulated
T9694 23836-23838 IN denotes in
T9695 23839-23847 NN denotes response
T9696 23848-23850 TO denotes to
T9697 23851-23854 NN denotes PMA
T9698 23855-23858 CC denotes and
T9699 23859-23861 NN denotes HK
T9700 23862-23864 FW denotes E.
T9701 23865-23869 FW denotes coli
T9702 23869-23870 -COMMA- denotes ,
T9703 23871-23881 VB denotes indicating
T9704 23882-23884 DT denotes an
T9705 23885-23896 NN denotes association
T9706 23897-23904 IN denotes between
T9707 23905-23908 NN denotes PKC
T9708 23909-23912 CC denotes and
T9709 23913-23916 DT denotes the
T9710 23917-23930 NN denotes transcription
T9711 23931-23938 NN denotes factors
T9712 23939-23943 NN denotes AP-1
T9713 23944-23947 CC denotes and
T9714 23948-23953 NN denotes NF-κB
T9715 23955-23960 NN denotes Bcl10
T9716 23961-23967 NN denotes levels
T9717 23968-23972 VB denotes were
T9718 23973-23987 VB denotes down-regulated
T9719 23988-23997 VB denotes following
T9720 23998-24006 VB denotes extended
T9721 24007-24016 NN denotes treatment
T9722 24017-24019 IN denotes of
T9723 24020-24026 NN denotes Jurkat
T9724 24027-24034 NN denotes T-cells
T9725 24035-24039 IN denotes with
T9726 24040-24043 NN denotes PMA
T9727 24045-24047 IN denotes In
T9728 24048-24051 DT denotes the
T9729 24052-24059 NN denotes control
T9730 24060-24066 NN denotes groups
T9731 24066-24067 -COMMA- denotes ,
T9732 24068-24069 DT denotes a
T9733 24070-24074 NN denotes loss
T9734 24075-24077 IN denotes of
T9735 24078-24083 NN denotes Bcl10
T9736 24084-24092 VB denotes occurred
T9737 24093-24098 IN denotes after
T9738 24099-24100 CD denotes 6
T9739 24101-24102 NN denotes h
T9740 24102-24103 -COMMA- denotes ,
T9741 24104-24112 VB denotes followed
T9742 24113-24115 IN denotes by
T9743 24116-24118 DT denotes an
T9744 24119-24127 NN denotes increase
T9745 24128-24133 IN denotes after
T9746 24134-24136 CD denotes 24
T9747 24137-24138 NN denotes h
T9748 24138-24139 -COMMA- denotes ,
T9749 24140-24145 WDT denotes which
T9750 24146-24148 VB denotes is
T9751 24149-24151 IN denotes in
T9752 24152-24162 NN denotes accordance
T9753 24163-24167 IN denotes with
T9754 24168-24171 DT denotes the
T9755 24172-24180 VB denotes observed
T9756 24181-24186 NN denotes NF-κB
T9757 24187-24195 NN denotes activity
T9758 24196-24197 -LRB- denotes (
T9759 24197-24203 NN denotes figure
T9760 24204-24205 CD denotes 7
T9761 24205-24206 -RRB- denotes )
T9762 24208-24213 DT denotes These
T9763 24214-24221 NN denotes results
T9764 24222-24225 VB denotes are
T9765 24226-24235 VB denotes supported
T9766 24236-24238 IN denotes by
T9767 24239-24241 DT denotes an
T9768 24242-24249 JJ denotes earlier
T9769 24250-24255 NN denotes study
T9770 24256-24257 -LRB- denotes [
T9771 24257-24259 CD denotes 47
T9772 24259-24260 -RRB- denotes ]
T9773 24260-24261 -COMMA- denotes ,
T9774 24262-24275 VB denotes demonstrating
T9775 24276-24280 IN denotes that
T9776 24281-24290 JJ denotes prolonged
T9777 24291-24294 NN denotes PKC
T9778 24295-24305 NN denotes activation
T9779 24306-24308 IN denotes by
T9780 24309-24312 NN denotes PMA
T9781 24313-24318 VB denotes leads
T9782 24319-24321 TO denotes to
T9783 24322-24324 DT denotes an
T9784 24325-24335 NN denotes inhibition
T9785 24336-24338 IN denotes of
T9786 24339-24344 NN denotes Bcl10
T9787 24345-24348 CC denotes and
T9788 24349-24354 NN denotes NF-κB
T9789 24356-24358 PRP denotes It
T9790 24359-24362 VB denotes has
T9791 24363-24367 VB denotes been
T9792 24368-24373 VB denotes shown
T9793 24374-24378 IN denotes that
T9794 24379-24384 NN denotes NF-κB
T9795 24385-24387 VB denotes is
T9796 24388-24390 DT denotes an
T9797 24391-24400 JJ denotes important
T9798 24401-24414 NN denotes transcription
T9799 24415-24421 NN denotes factor
T9800 24422-24429 NN denotes complex
T9801 24430-24438 VB denotes involved
T9802 24439-24441 IN denotes in
T9803 24442-24448 RB denotes almost
T9804 24449-24454 DT denotes every
T9805 24455-24461 NN denotes aspect
T9806 24462-24464 IN denotes of
T9807 24465-24469 NN denotes cell
T9808 24470-24480 NN denotes regulation
T9809 24481-24490 VB denotes including
T9810 24491-24500 NN denotes apoptosis
T9811 24500-24501 -COMMA- denotes ,
T9812 24502-24517 NN denotes differentiation
T9813 24517-24518 -COMMA- denotes ,
T9814 24519-24532 NN denotes proliferation
T9815 24533-24536 CC denotes and
T9816 24537-24547 NN denotes initiation
T9817 24548-24550 IN denotes of
T9818 24551-24557 JJ denotes immune
T9819 24558-24567 NN denotes responses
T9820 24568-24569 -LRB- denotes [
T9821 24569-24574 CD denotes 51-53
T9822 24574-24575 -RRB- denotes ]
T9823 24577-24582 NN denotes NF-κB
T9824 24583-24585 VB denotes is
T9825 24586-24600 RB denotes constitutively
T9826 24601-24607 JJ denotes active
T9827 24608-24610 IN denotes in
T9828 24611-24615 JJ denotes many
T9829 24616-24621 JJ denotes human
T9830 24622-24634 NN denotes malignancies
T9831 24634-24635 -COMMA- denotes ,
T9832 24636-24641 WDT denotes which
T9833 24642-24647 VB denotes makes
T9834 24648-24650 PRP denotes it
T9835 24651-24653 DT denotes an
T9836 24654-24664 JJ denotes attractive
T9837 24665-24676 JJ denotes therapeutic
T9838 24677-24683 NN denotes target
T9839 24684-24685 -LRB- denotes [
T9840 24685-24687 CD denotes 54
T9841 24687-24688 -RRB- denotes ]
T9842 24690-24698 JJ denotes Elevated
T9843 24699-24704 NN denotes CXCL8
T9844 24705-24711 NN denotes levels
T9845 24712-24718 IN denotes during
T9846 24719-24726 JJ denotes chronic
T9847 24727-24739 NN denotes inflammation
T9848 24740-24746 VB denotes result
T9849 24747-24749 IN denotes in
T9850 24750-24752 DT denotes an
T9851 24753-24761 VB denotes enhanced
T9852 24762-24773 NN denotes recruitment
T9853 24774-24776 IN denotes of
T9854 24777-24783 JJ denotes immune
T9855 24784-24789 NN denotes cells
T9856 24790-24792 TO denotes to
T9857 24793-24796 DT denotes the
T9858 24797-24801 NN denotes site
T9859 24802-24804 IN denotes of
T9860 24805-24814 NN denotes infection
T9861 24814-24815 -COMMA- denotes ,
T9862 24816-24821 WDT denotes which
T9863 24822-24825 MD denotes may
T9864 24826-24830 VB denotes lead
T9865 24831-24833 TO denotes to
T9866 24834-24837 DT denotes the
T9867 24838-24849 NN denotes development
T9868 24850-24852 IN denotes of
T9869 24853-24863 JJ denotes autoimmune
T9870 24864-24872 NN denotes diseases
T9871 24873-24882 VB denotes following
T9872 24883-24892 NN denotes secretion
T9873 24893-24895 IN denotes of
T9874 24896-24912 JJ denotes pro-inflammatory
T9875 24913-24922 NN denotes cytokines
T9876 24924-24926 IN denotes In
T9877 24927-24930 NN denotes HIV
T9878 24931-24939 JJ denotes infected
T9879 24940-24947 NN denotes persons
T9880 24947-24948 -COMMA- denotes ,
T9881 24949-24954 NN denotes serum
T9882 24955-24960 NN denotes CXCL8
T9883 24961-24967 NN denotes levels
T9884 24968-24971 VB denotes are
T9885 24972-24980 VB denotes elevated
T9886 24981-24984 CC denotes and
T9887 24985-24989 DT denotes this
T9888 24990-24995 MD denotes could
T9889 24996-25003 VB denotes recruit
T9890 25004-25008 JJ denotes more
T9891 25009-25016 NN denotes T-cells
T9892 25017-25028 RB denotes potentially
T9893 25029-25036 VB denotes leading
T9894 25037-25039 TO denotes to
T9895 25040-25041 DT denotes a
T9896 25042-25046 RB denotes more
T9897 25047-25052 JJ denotes rapid
T9898 25053-25064 NN denotes progression
T9899 25065-25067 IN denotes of
T9900 25068-25071 DT denotes the
T9901 25072-25079 NN denotes disease
T9902 25080-25085 IN denotes since
T9903 25086-25091 EX denotes there
T9904 25092-25096 MD denotes will
T9905 25097-25099 VB denotes be
T9906 25100-25104 JJ denotes more
T9907 25105-25112 NN denotes T-cells
T9908 25113-25122 JJ denotes available
T9909 25123-25125 TO denotes to
T9910 25126-25132 VB denotes infect
T11617 25146-25148 IN denotes In
T11618 25149-25152 DT denotes the
T11619 25153-25160 JJ denotes present
T11620 25161-25166 NN denotes study
T11621 25166-25167 -COMMA- denotes ,
T11622 25168-25172 NN denotes IL-6
T11623 25173-25180 NN denotes release
T11624 25181-25184 VB denotes was
T11625 25185-25190 VB denotes found
T11626 25191-25193 TO denotes to
T11627 25194-25196 VB denotes be
T11628 25197-25207 VB denotes associated
T11629 25208-25212 IN denotes with
T11630 25213-25218 NN denotes NF-κB
T11631 25219-25227 NN denotes activity
T11632 25228-25233 IN denotes while
T11633 25234-25239 NN denotes CXCL8
T11634 25240-25247 NN denotes release
T11635 25248-25252 RB denotes more
T11636 25253-25260 RB denotes closely
T11637 25261-25271 VB denotes correlated
T11638 25272-25276 IN denotes with
T11639 25277-25281 NN denotes AP-1
T11640 25282-25290 NN denotes activity
T11641 25292-25301 NN denotes Treatment
T11642 25302-25304 IN denotes of
T11643 25305-25311 NN denotes Jurkat
T11644 25312-25319 NN denotes T-cells
T11645 25320-25324 IN denotes with
T11646 25325-25328 NN denotes PMA
T11647 25329-25332 VB denotes was
T11648 25333-25337 RB denotes more
T11649 25338-25344 JJ denotes potent
T11650 25345-25349 IN denotes than
T11651 25350-25352 NN denotes HK
T11652 25353-25355 FW denotes E.
T11653 25356-25360 FW denotes coli
T11654 25361-25363 IN denotes at
T11655 25364-25373 VB denotes elevating
T11656 25374-25377 DT denotes the
T11657 25378-25383 NN denotes CXCL8
T11658 25384-25390 NN denotes levels
T11659 25392-25395 NN denotes PMA
T11660 25396-25403 VB denotes induced
T11661 25404-25408 NN denotes AP-1
T11662 25409-25419 NN denotes activation
T11663 25420-25423 CC denotes and
T11664 25424-25438 VB denotes down-regulated
T11665 25439-25444 NN denotes NF-κB
T11666 25445-25450 IN denotes while
T11667 25451-25453 NN denotes HK
T11668 25454-25456 FW denotes E.
T11669 25457-25461 FW denotes coli
T11670 25462-25474 VB denotes up-regulated
T11671 25475-25480 NN denotes NF-κB
T11672 25481-25488 IN denotes without
T11673 25489-25498 VB denotes affecting
T11674 25499-25503 NN denotes AP-1
T11675 25504-25512 NN denotes activity
T11676 25514-25516 IN denotes In
T11677 25517-25525 NN denotes addition
T11678 25525-25526 -COMMA- denotes ,
T11679 25527-25530 DT denotes the
T11680 25531-25539 JJ denotes temporal
T11681 25540-25549 NN denotes induction
T11682 25550-25557 NN denotes pattern
T11683 25558-25560 IN denotes of
T11684 25561-25565 NN denotes AP-1
T11685 25566-25576 VB denotes correlated
T11686 25577-25579 TO denotes to
T11687 25580-25583 DT denotes the
T11688 25584-25591 NN denotes release
T11689 25592-25594 IN denotes of
T11690 25595-25600 NN denotes CXCL8
T11691 25601-25606 IN denotes while
T11692 25607-25611 NN denotes IL-6
T11693 25612-25620 VB denotes followed
T11694 25621-25624 DT denotes the
T11695 25625-25630 NN denotes NF-κB
T11696 25631-25639 NN denotes activity
T11697 25641-25649 RB denotes Likewise
T11698 25649-25650 -COMMA- denotes ,
T11699 25651-25659 VB denotes blocking
T11700 25660-25665 NN denotes NF-κB
T11701 25666-25676 NN denotes activation
T11702 25677-25685 VB denotes resulted
T11703 25686-25688 IN denotes in
T11704 25689-25690 DT denotes a
T11705 25691-25699 JJ denotes complete
T11706 25700-25710 NN denotes inhibition
T11707 25711-25713 IN denotes of
T11708 25714-25718 NN denotes IL-6
T11709 25719-25724 IN denotes while
T11710 25725-25728 DT denotes the
T11711 25729-25734 NN denotes CXCL8
T11712 25735-25741 NN denotes levels
T11713 25742-25750 VB denotes remained
T11714 25751-25759 JJ denotes elevated
T11715 25760-25762 IN denotes as
T11716 25763-25768 VB denotes shown
T11717 25769-25773 CC denotes both
T11718 25774-25776 IN denotes at
T11719 25777-25780 DT denotes the
T11720 25781-25788 NN denotes protein
T11721 25789-25792 CC denotes and
T11722 25793-25797 NN denotes mRNA
T11723 25798-25803 NN denotes level
T11724 25805-25816 RB denotes Furthermore
T11725 25816-25817 -COMMA- denotes ,
T11726 25818-25821 DT denotes the
T11727 25822-25827 NN denotes CXCL8
T11728 25828-25835 NN denotes release
T11729 25836-25839 VB denotes was
T11730 25840-25854 VB denotes down-regulated
T11731 25855-25857 IN denotes by
T11732 25858-25868 NN denotes inhibition
T11733 25869-25871 IN denotes of
T11734 25872-25875 NN denotes JNK
T11735 25876-25884 NN denotes activity
T11736 25886-25889 DT denotes The
T11737 25890-25897 JJ denotes present
T11738 25898-25903 NN denotes study
T11739 25904-25913 VB denotes indicates
T11740 25914-25918 IN denotes that
T11741 25919-25921 IN denotes in
T11742 25922-25928 NN denotes Jurkat
T11743 25929-25936 NN denotes T-cells
T11744 25936-25937 -COMMA- denotes ,
T11745 25938-25942 NN denotes IL-6
T11746 25943-25945 VB denotes is
T11747 25946-25955 VB denotes regulated
T11748 25956-25963 IN denotes through
T11749 25964-25969 NN denotes NF-κB
T11750 25970-25975 IN denotes while
T11751 25976-25981 NN denotes CXCL8
T11752 25982-25992 NN denotes regulation
T11753 25993-25995 VB denotes is
T11754 25996-26007 JJ denotes independent
T11755 26008-26010 IN denotes of
T11756 26011-26016 NN denotes NF-κB
T11757 26017-26020 CC denotes and
T11758 26021-26028 RB denotes closely
T11759 26029-26039 VB denotes associated
T11760 26040-26044 IN denotes with
T11761 26045-26049 NN denotes AP-1
T11762 26050-26060 NN denotes activation
T12072 26086-26095 NN denotes Chemicals
T12073 26096-26099 DT denotes The
T12074 26100-26109 VB denotes following
T12075 26110-26119 NN denotes chemicals
T12076 26120-26124 VB denotes were
T12077 26125-26129 VB denotes used
T12078 26130-26132 IN denotes in
T12079 26133-26136 DT denotes the
T12080 26137-26144 JJ denotes present
T12081 26145-26150 NN denotes study
T12082 26150-26151 -COLON- denotes :
T12083 26152-26155 NN denotes PMA
T12084 26156-26157 -LRB- denotes (
T12085 26157-26164 NN denotes Phorbol
T12086 26165-26177 NN denotes 12-myristate
T12087 26178-26188 NN denotes 13-acetate
T12088 26188-26189 -COMMA- denotes ,
T12089 26190-26191 -LRB- denotes (
T12090 26191-26196 NNP denotes Sigma
T12091 26197-26198 -SHARP- denotes #
T12092 26198-26203 NNP denotes P1585
T12093 26203-26204 -COMMA- denotes ,
T12094 26205-26208 NNP denotes USA
T12095 26208-26209 -RRB- denotes )
T12096 26209-26210 -RRB- denotes )
T12097 26210-26211 -COLON- denotes ;
T12098 26212-26217 NN denotes NF-κB
T12099 26218-26228 NN denotes activation
T12100 26229-26238 NN denotes inhibitor
T12101 26239-26240 -LRB- denotes (
T12102 26240-26243 NN denotes NAI
T12103 26243-26244 -RRB- denotes )
T12104 26244-26245 -COMMA- denotes ,
T12105 26246-26247 -LRB- denotes (
T12106 26247-26258 NNP denotes InSolution™
T12107 26259-26264 NN denotes NF-κB
T12108 26265-26275 NN denotes Activation
T12109 26276-26285 NN denotes Inhibitor
T12110 26285-26286 -COMMA- denotes ,
T12111 26287-26297 NNP denotes Calbiochem
T12112 26298-26299 -SHARP- denotes #
T12113 26299-26305 CD denotes 481407
T12114 26305-26306 -COMMA- denotes ,
T12115 26307-26310 NNP denotes USA
T12116 26310-26311 -RRB- denotes )
T12117 26311-26312 -COLON- denotes ;
T12118 26313-26316 NN denotes JNK
T12119 26317-26326 NN denotes inhibitor
T12120 26326-26327 -COMMA- denotes ,
T12121 26328-26329 -LRB- denotes (
T12122 26329-26340 NNP denotes InSolution™
T12123 26341-26344 NNP denotes JNK
T12124 26345-26354 NN denotes Inhibitor
T12125 26355-26357 CD denotes II
T12126 26357-26358 -COMMA- denotes ,
T12127 26359-26369 NNP denotes Calbiochem
T12128 26370-26371 -SHARP- denotes #
T12129 26371-26377 CD denotes 420128
T12130 26377-26378 -COMMA- denotes ,
T12131 26379-26382 NNP denotes USA
T12132 26382-26383 -RRB- denotes )
T12133 26383-26384 -COLON- denotes ;
T12134 26385-26388 NN denotes PKC
T12135 26389-26398 NN denotes Inhibitor
T12136 26398-26399 -COMMA- denotes ,
T12137 26400-26401 -LRB- denotes (
T12138 26401-26412 NNP denotes InSolution™
T12139 26413-26432 NNP denotes Bisindolylmaleimide
T12140 26433-26434 NNP denotes I
T12141 26434-26435 -COMMA- denotes ,
T12142 26436-26446 NNP denotes Calbiochem
T12143 26447-26448 -SHARP- denotes #
T12144 26448-26454 CD denotes 203293
T12145 26454-26455 -COMMA- denotes ,
T12146 26456-26459 NNP denotes USA
T12147 26459-26460 -RRB- denotes )
T12148 26460-26461 -COLON- denotes ;
T12149 26462-26469 NNP denotes Calcium
T12150 26470-26479 NNP denotes Ionophore
T12151 26479-26480 -COMMA- denotes ,
T12152 26481-26482 -LRB- denotes (
T12153 26482-26489 NNP denotes Calcium
T12154 26490-26499 NNP denotes Ionophore
T12155 26500-26506 NN denotes A23187
T12156 26507-26512 JJ denotes mixed
T12157 26513-26520 NN denotes calcium
T12158 26521-26530 NN denotes magnesium
T12159 26531-26535 NN denotes salt
T12160 26535-26536 -COMMA- denotes ,
T12161 26537-26542 NNP denotes Sigma
T12162 26543-26544 -SHARP- denotes #
T12163 26544-26549 NNP denotes C5149
T12164 26549-26550 -COMMA- denotes ,
T12165 26551-26554 NNP denotes USA
T12166 26554-26555 -RRB- denotes )
T12332 26558-26562 NNP denotes Heat
T12333 26563-26569 VB denotes killed
T12334 26570-26571 -LRB- denotes (
T12335 26571-26573 NN denotes HK
T12336 26573-26574 -RRB- denotes )
T12337 26575-26586 FW denotes Escherichia
T12338 26587-26591 FW denotes coli
T12339 26592-26594 FW denotes E.
T12340 26595-26599 FW denotes coli
T12341 26600-26606 NN denotes MG1655
T12342 26607-26611 VB denotes were
T12343 26612-26617 VB denotes grown
T12344 26618-26620 IN denotes on
T12345 26621-26634 NNP denotes Luria-Bertani
T12346 26635-26636 -LRB- denotes (
T12347 26636-26638 NN denotes LB
T12348 26638-26639 -RRB- denotes )
T12349 26640-26644 NN denotes agar
T12350 26645-26648 CC denotes and
T12351 26649-26658 VB denotes incubated
T12352 26659-26661 IN denotes at
T12353 26662-26666 NN denotes 37°C
T12354 26667-26676 RB denotes overnight
T12355 26678-26681 CD denotes One
T12356 26682-26688 NN denotes colony
T12357 26689-26692 VB denotes was
T12358 26693-26703 VB denotes inoculated
T12359 26704-26708 IN denotes into
T12360 26709-26711 CD denotes 10
T12361 26712-26714 NN denotes ml
T12362 26715-26717 NN denotes LB
T12363 26718-26723 NN denotes broth
T12364 26724-26727 CC denotes and
T12365 26728-26737 VB denotes incubated
T12366 26738-26740 IN denotes on
T12367 26741-26742 DT denotes a
T12368 26743-26749 NN denotes shaker
T12369 26750-26751 -LRB- denotes (
T12370 26751-26754 CD denotes 200
T12371 26755-26758 NN denotes rpm
T12372 26758-26759 -RRB- denotes )
T12373 26760-26762 IN denotes at
T12374 26763-26767 NN denotes 37°C
T12375 26768-26777 RB denotes overnight
T12376 26779-26782 DT denotes The
T12377 26783-26791 NN denotes bacteria
T12378 26792-26796 VB denotes were
T12379 26797-26808 VB denotes centrifuged
T12380 26809-26812 IN denotes for
T12381 26813-26815 CD denotes 10
T12382 26816-26819 NN denotes min
T12383 26820-26822 IN denotes at
T12384 26823-26827 CD denotes 3000
T12385 26828-26829 SYM denotes ×
T12386 26830-26831 NN denotes g
T12387 26831-26832 -COMMA- denotes ,
T12388 26833-26839 VB denotes washed
T12389 26840-26844 IN denotes with
T12390 26845-26846 CD denotes 3
T12391 26847-26849 NN denotes ml
T12392 26850-26859 NN denotes phosphate
T12393 26860-26868 VB denotes buffered
T12394 26869-26875 NN denotes saline
T12395 26876-26877 -LRB- denotes (
T12396 26877-26880 NN denotes PBS
T12397 26880-26881 -COLON- denotes ;
T12398 26882-26883 CD denotes 8
T12399 26884-26885 NN denotes g
T12400 26886-26890 NN denotes NaCl
T12401 26890-26891 -COMMA- denotes ,
T12402 26892-26896 CD denotes 1.16
T12403 26897-26898 NN denotes g
T12404 26899-26906 NN denotes Na2HPO4
T12405 26906-26907 -COMMA- denotes ,
T12406 26908-26911 CD denotes 0.2
T12407 26912-26913 NN denotes g
T12408 26914-26920 NN denotes KH2PO4
T12409 26920-26921 -COMMA- denotes ,
T12410 26922-26925 CD denotes 0.2
T12411 26926-26927 NN denotes g
T12412 26928-26931 NN denotes KCl
T12413 26931-26932 -COMMA- denotes ,
T12414 26933-26936 NN denotes pH7
T12415 26936-26937 -RRB- denotes )
T12416 26938-26941 CC denotes and
T12417 26942-26953 VB denotes resuspended
T12418 26954-26956 IN denotes in
T12419 26957-26959 CD denotes 50
T12420 26960-26962 NNP denotes μl
T12421 26963-26966 NNP denotes PBS
T12422 26968-26971 DT denotes The
T12423 26972-26980 NN denotes bacteria
T12424 26981-26985 VB denotes were
T12425 26986-26992 VB denotes killed
T12426 26993-26995 IN denotes by
T12427 26996-27003 VB denotes heating
T12428 27004-27006 TO denotes to
T12429 27007-27011 NN denotes 70°C
T12430 27012-27015 IN denotes for
T12431 27016-27017 CD denotes 1
T12432 27018-27019 NN denotes h
T12433 27021-27023 TO denotes To
T12434 27024-27030 VB denotes ensure
T12435 27031-27035 IN denotes that
T12436 27036-27039 DT denotes the
T12437 27040-27048 NN denotes bacteria
T12438 27049-27053 VB denotes were
T12439 27054-27060 VB denotes killed
T12440 27060-27061 -COLON- denotes ;
T12441 27062-27064 CD denotes 10
T12442 27065-27067 NN denotes μl
T12443 27068-27070 IN denotes of
T12444 27071-27074 DT denotes the
T12445 27075-27086 JJ denotes heat-killed
T12446 27087-27097 NN denotes suspension
T12447 27098-27101 VB denotes was
T12448 27102-27108 VB denotes spread
T12449 27109-27111 IN denotes on
T12450 27112-27113 DT denotes a
T12451 27114-27116 NN denotes LB
T12452 27117-27122 NN denotes plate
T12453 27123-27126 CC denotes and
T12454 27127-27136 VB denotes incubated
T12455 27137-27146 RB denotes overnight
T12456 27147-27149 IN denotes at
T12457 27150-27154 NN denotes 37°C
T12823 27157-27161 NN denotes Cell
T12824 27162-27171 NN denotes culturing
T12825 27171-27172 -COMMA- denotes ,
T12826 27173-27185 NN denotes transfection
T12827 27186-27189 CC denotes and
T12828 27190-27201 NN denotes stimulation
T12829 27202-27208 NN denotes Jurkat
T12830 27209-27216 NN denotes T-cells
T12831 27217-27218 -LRB- denotes (
T12832 27218-27222 JJ denotes wild
T12833 27223-27227 NN denotes type
T12834 27228-27231 CC denotes and
T12835 27232-27235 NN denotes TCR
T12836 27236-27246 NN denotes deficient-
T12837 27247-27253 JJ denotes TCR-/-
T12838 27253-27254 -RRB- denotes )
T12839 27255-27259 VB denotes were
T12840 27260-27270 VB denotes maintained
T12841 27271-27273 IN denotes in
T12842 27274-27276 CD denotes 90
T12843 27276-27277 NN denotes %
T12844 27278-27282 NN denotes RPMI
T12845 27283-27287 CD denotes 1640
T12846 27288-27294 NN denotes medium
T12847 27295-27296 -LRB- denotes (
T12848 27296-27299 NN denotes PAA
T12849 27300-27312 NN denotes laboratories
T12850 27312-27313 -COMMA- denotes ,
T12851 27314-27321 NNP denotes Austria
T12852 27321-27322 -RRB- denotes )
T12853 27323-27327 IN denotes with
T12854 27328-27331 CD denotes 1.5
T12855 27332-27334 NN denotes mM
T12856 27335-27346 NN denotes L-glutamine
T12857 27347-27348 -LRB- denotes (
T12858 27348-27358 NN denotes Invitrogen
T12859 27358-27359 -COMMA- denotes ,
T12860 27360-27363 NNP denotes USA
T12861 27363-27364 -RRB- denotes )
T12862 27364-27365 -COMMA- denotes ,
T12863 27366-27368 CD denotes 10
T12864 27368-27369 NN denotes %
T12865 27370-27376 JJ denotes foetal
T12866 27377-27383 JJ denotes bovine
T12867 27384-27389 NN denotes serum
T12868 27390-27391 -LRB- denotes (
T12869 27391-27401 NN denotes Invitrogen
T12870 27401-27402 -COMMA- denotes ,
T12871 27403-27406 NNP denotes USA
T12872 27406-27407 -RRB- denotes )
T12873 27408-27411 CC denotes and
T12874 27412-27413 CD denotes 1
T12875 27413-27414 NN denotes %
T12876 27415-27437 JJ denotes antibiotic-antimycotic
T12877 27438-27439 -LRB- denotes (
T12878 27439-27449 NN denotes Invitrogen
T12879 27449-27450 -COMMA- denotes ,
T12880 27451-27454 NNP denotes USA
T12881 27454-27455 -RRB- denotes )
T12882 27456-27459 CC denotes and
T12883 27460-27469 VB denotes incubated
T12884 27470-27472 IN denotes in
T12885 27473-27474 DT denotes a
T12886 27475-27481 JJ denotes stable
T12887 27482-27493 NN denotes environment
T12888 27494-27496 IN denotes of
T12889 27497-27498 CD denotes 5
T12890 27498-27499 NN denotes %
T12891 27500-27503 NN denotes CO2
T12892 27504-27506 IN denotes at
T12893 27507-27511 NN denotes 37°C
T12894 27513-27516 DT denotes The
T12895 27517-27522 NN denotes cells
T12896 27523-27527 VB denotes were
T12897 27528-27539 VB denotes centrifuged
T12898 27540-27542 IN denotes at
T12899 27543-27547 CD denotes 1000
T12900 27548-27549 SYM denotes ×
T12901 27550-27551 NN denotes g
T12902 27552-27555 IN denotes for
T12903 27556-27557 CD denotes 8
T12904 27558-27561 NN denotes min
T12905 27562-27565 CC denotes and
T12906 27566-27577 VB denotes resuspended
T12907 27578-27580 IN denotes in
T12908 27581-27586 JJ denotes fresh
T12909 27587-27592 NN denotes media
T12910 27593-27595 TO denotes to
T12911 27596-27597 DT denotes a
T12912 27598-27603 JJ denotes final
T12913 27604-27608 NN denotes cell
T12914 27609-27616 NN denotes density
T12915 27617-27619 IN denotes of
T12916 27620-27623 CD denotes 1.6
T12917 27624-27625 CC denotes ×
T12918 27626-27629 CD denotes 107
T12919 27630-27638 NN denotes cells/ml
T12920 27639-27641 IN denotes in
T12921 27642-27643 DT denotes a
T12922 27644-27651 JJ denotes 24-well
T12923 27652-27657 NN denotes plate
T12924 27659-27667 NN denotes Reporter
T12925 27668-27675 NN denotes plasmid
T12926 27676-27677 -LRB- denotes (
T12927 27677-27686 NN denotes pNFκB-Luc
T12928 27686-27687 -COMMA- denotes ,
T12929 27688-27692 NN denotes pAP1
T12930 27693-27694 -LRB- denotes (
T12931 27694-27697 NN denotes PMA
T12932 27697-27698 -RRB- denotes )
T12933 27698-27705 NN denotes -TA-Luc
T12934 27705-27706 -COMMA- denotes ,
T12935 27707-27717 NN denotes pNFκB-SEAP
T12936 27717-27718 -RRB- denotes )
T12937 27718-27719 -COMMA- denotes ,
T12938 27720-27728 JJ denotes internal
T12939 27729-27736 NN denotes control
T12940 27737-27744 NN denotes plasmid
T12941 27745-27746 -LRB- denotes (
T12942 27746-27749 NN denotes pRL
T12943 27749-27750 -RRB- denotes )
T12944 27751-27752 -LRB- denotes (
T12945 27752-27759 NNP denotes Promega
T12946 27759-27760 -COMMA- denotes ,
T12947 27761-27764 NNP denotes USA
T12948 27764-27765 -RRB- denotes )
T12949 27766-27769 CC denotes and
T12950 27770-27783 NN denotes lipofectamine
T12951 27784-27788 CD denotes 2000
T12952 27789-27790 -LRB- denotes (
T12953 27790-27800 NN denotes Invitrogen
T12954 27800-27801 -COMMA- denotes ,
T12955 27802-27805 NNP denotes USA
T12956 27805-27806 -RRB- denotes )
T12957 27807-27811 VB denotes were
T12958 27812-27817 VB denotes added
T12959 27818-27820 TO denotes to
T12960 27821-27825 DT denotes each
T12961 27826-27830 RB denotes well
T12962 27831-27833 IN denotes at
T12963 27834-27838 CD denotes 0.54
T12964 27839-27846 RB denotes μg/well
T12965 27846-27847 -COMMA- denotes ,
T12966 27848-27852 CD denotes 0.06
T12967 27853-27860 JJ denotes μg/well
T12968 27861-27864 CC denotes and
T12969 27865-27868 CD denotes 1.5
T12970 27869-27876 NN denotes μl/well
T12971 27876-27877 -COMMA- denotes ,
T12972 27878-27890 RB denotes respectively
T12973 27892-27901 RB denotes Initially
T12974 27901-27902 -COMMA- denotes ,
T12975 27903-27906 DT denotes the
T12976 27907-27915 NN denotes reporter
T12977 27916-27923 NN denotes plasmid
T12978 27924-27927 CC denotes and
T12979 27928-27931 NN denotes pRL
T12980 27932-27936 VB denotes were
T12981 27937-27942 VB denotes mixed
T12982 27943-27953 RB denotes separately
T12983 27954-27958 IN denotes with
T12984 27959-27966 NN denotes OptiMEM
T12985 27967-27968 -LRB- denotes (
T12986 27968-27973 NNP denotes Gibco
T12987 27973-27974 -COMMA- denotes ,
T12988 27975-27978 NNP denotes USA
T12989 27978-27979 -RRB- denotes )
T12990 27981-27986 IN denotes After
T12991 27987-27988 CD denotes 5
T12992 27989-27992 NN denotes min
T12993 27993-27995 IN denotes of
T12994 27996-28006 NN denotes incubation
T12995 28007-28009 IN denotes at
T12996 28010-28014 NN denotes room
T12997 28015-28026 NN denotes temperature
T12998 28026-28027 -COMMA- denotes ,
T12999 28028-28041 NN denotes lipofectamine
T13000 28042-28046 CD denotes 2000
T13001 28047-28050 VB denotes was
T13002 28051-28056 VB denotes added
T13003 28057-28060 CC denotes and
T13004 28061-28064 DT denotes the
T13005 28065-28072 NN denotes mixture
T13006 28073-28076 VB denotes was
T13007 28077-28086 VB denotes incubated
T13008 28087-28094 RB denotes further
T13009 28095-28098 IN denotes for
T13010 28099-28101 CD denotes 20
T13011 28102-28105 NN denotes min
T13012 28106-28108 IN denotes at
T13013 28109-28113 NN denotes room
T13014 28114-28125 NN denotes temperature
T13015 28127-28130 DT denotes The
T13016 28131-28143 NN denotes transfection
T13017 28144-28147 VB denotes was
T13018 28148-28155 VB denotes allowed
T13019 28156-28158 TO denotes to
T13020 28159-28166 VB denotes proceed
T13021 28167-28176 RB denotes overnight
T13022 28177-28179 IN denotes at
T13023 28180-28184 NN denotes 37°C
T13024 28184-28185 -COMMA- denotes ,
T13025 28186-28191 IN denotes after
T13026 28192-28197 WDT denotes which
T13027 28197-28198 -COMMA- denotes ,
T13028 28199-28202 DT denotes the
T13029 28203-28208 NN denotes cells
T13030 28209-28213 VB denotes were
T13031 28214-28225 VB denotes centrifuged
T13032 28225-28226 -COMMA- denotes ,
T13033 28227-28230 DT denotes the
T13034 28231-28236 NN denotes media
T13035 28237-28244 VB denotes removed
T13036 28245-28248 CC denotes and
T13037 28249-28254 JJ denotes fresh
T13038 28255-28265 JJ denotes pre-warmed
T13039 28266-28271 NN denotes media
T13040 28272-28277 VB denotes added
T13041 28279-28282 DT denotes The
T13042 28283-28288 NN denotes cells
T13043 28289-28293 VB denotes were
T13044 28294-28307 JJ denotes pre-incubated
T13045 28308-28312 IN denotes with
T13046 28313-28318 NN denotes NF-κB
T13047 28318-28319 -COMMA- denotes ,
T13048 28320-28323 NN denotes JNK
T13049 28324-28327 CC denotes and
T13050 28328-28331 NN denotes PKC
T13051 28332-28342 NN denotes inhibitors
T13052 28343-28346 CC denotes and
T13053 28347-28357 VB denotes stimulated
T13054 28358-28360 IN denotes in
T13055 28361-28368 JJ denotes 24-well
T13056 28369-28375 NN denotes plates
T13057 28376-28380 IN denotes with
T13058 28381-28390 JJ denotes different
T13059 28391-28405 NN denotes concentrations
T13060 28406-28408 IN denotes of
T13061 28409-28412 NN denotes PMA
T13062 28412-28413 -COMMA- denotes ,
T13063 28414-28416 NN denotes HK
T13064 28417-28419 FW denotes E.
T13065 28420-28424 FW denotes coli
T13066 28425-28431 NN denotes MG1655
T13067 28432-28435 CC denotes and
T13068 28436-28443 NNP denotes Calcium
T13069 28444-28453 NNP denotes Ionophore
T13070 28454-28460 NN denotes A23187
T13071 28462-28465 DT denotes The
T13072 28466-28471 NN denotes cells
T13073 28472-28476 VB denotes were
T13074 28477-28482 VB denotes lysed
T13075 28483-28486 CC denotes and
T13076 28487-28497 NN denotes luciferase
T13077 28498-28506 NN denotes activity
T13078 28507-28508 -LRB- denotes (
T13079 28508-28513 NN denotes NF-κB
T13080 28514-28517 CC denotes and
T13081 28518-28522 NN denotes AP-1
T13082 28522-28523 -RRB- denotes )
T13083 28524-28527 VB denotes was
T13084 28528-28536 VB denotes measured
T13085 28537-28542 VB denotes using
T13086 28543-28546 DT denotes the
T13087 28547-28563 JJ denotes Dual-Luciferase®
T13088 28564-28572 NN denotes reporter
T13089 28573-28578 NN denotes assay
T13090 28579-28585 NN denotes system
T13091 28586-28587 -LRB- denotes (
T13092 28587-28594 NNP denotes Promega
T13093 28594-28595 -COMMA- denotes ,
T13094 28596-28599 NNP denotes USA
T13095 28599-28600 -RRB- denotes )
T13096 28601-28610 VB denotes according
T13097 28611-28613 TO denotes to
T13098 28614-28617 DT denotes the
T13099 28618-28630 NN denotes manufacturer
T13100 28630-28632 POS denotes 's
T13101 28633-28645 NN denotes instructions
T13102 28646-28648 IN denotes on
T13103 28649-28650 DT denotes a
T13104 28651-28653 NN denotes TD
T13105 28654-28659 CD denotes 20/20
T13106 28660-28671 NN denotes luminometer
T13107 28672-28673 -LRB- denotes (
T13108 28673-28679 NNP denotes Turner
T13109 28680-28687 NNP denotes Designs
T13110 28687-28688 -COMMA- denotes ,
T13111 28689-28698 NNP denotes Sunnyvale
T13112 28698-28699 -COMMA- denotes ,
T13113 28700-28702 NNP denotes CA
T13114 28702-28703 -RRB- denotes )
T13115 28705-28713 VB denotes Secreted
T13116 28714-28722 NN denotes alkaline
T13117 28723-28734 NN denotes phosphatase
T13118 28735-28736 -LRB- denotes (
T13119 28736-28745 NN denotes NFκB-SEAP
T13120 28745-28746 -COMMA- denotes ,
T13121 28747-28753 NN denotes figure
T13122 28754-28756 NN denotes 4a
T13123 28756-28757 -COMMA- denotes ,
T13124 28758-28759 NN denotes b
T13125 28759-28760 -RRB- denotes )
T13126 28761-28767 NN denotes levels
T13127 28768-28772 VB denotes were
T13128 28773-28781 VB denotes measured
T13129 28782-28787 VB denotes using
T13130 28788-28793 NNP denotes Great
T13131 28794-28801 NNP denotes EscAPe™
T13132 28802-28806 NNP denotes SEAP
T13133 28807-28816 NNP denotes Detection
T13134 28817-28820 NN denotes Kit
T13135 28821-28822 -LRB- denotes (
T13136 28822-28830 NNP denotes Clontech
T13137 28830-28831 -COMMA- denotes ,
T13138 28832-28835 NNP denotes USA
T13139 28835-28836 -RRB- denotes )
T13302 28839-28848 JJ denotes Multiplex
T13303 28849-28857 NN denotes cytokine
T13304 28858-28863 NN denotes assay
T13305 28864-28878 NN denotes Quantification
T13306 28879-28881 IN denotes of
T13307 28882-28885 DT denotes the
T13308 28886-28892 NN denotes levels
T13309 28893-28895 IN denotes of
T13310 28896-28905 NN denotes cytokines
T13311 28906-28910 NN denotes IL-2
T13312 28910-28911 -COMMA- denotes ,
T13313 28912-28916 NN denotes IL-6
T13314 28916-28917 -COMMA- denotes ,
T13315 28918-28923 NN denotes IL-10
T13316 28924-28927 CC denotes and
T13317 28928-28931 NN denotes TNF
T13318 28932-28935 CC denotes and
T13319 28936-28939 DT denotes the
T13320 28940-28949 NN denotes chemokine
T13321 28950-28955 NN denotes CXCL8
T13322 28956-28959 VB denotes was
T13323 28960-28969 VB denotes performed
T13324 28970-28972 IN denotes on
T13325 28973-28980 NN denotes culture
T13326 28981-28993 NN denotes supernatants
T13327 28994-28999 VB denotes using
T13328 29000-29011 JJ denotes multiplexed
T13329 29012-29021 NN denotes biomarker
T13330 29022-29033 NN denotes immunoassay
T13331 29034-29038 NN denotes kits
T13332 29039-29048 VB denotes according
T13333 29049-29051 TO denotes to
T13334 29052-29064 NN denotes manufacturer
T13335 29064-29066 POS denotes 's
T13336 29067-29079 NN denotes instructions
T13337 29080-29081 -LRB- denotes (
T13338 29081-29088 NNP denotes Bio-Rad
T13339 29089-29101 NNP denotes Laboratories
T13340 29101-29102 -COMMA- denotes ,
T13341 29103-29111 NNP denotes Hercules
T13342 29111-29112 -COMMA- denotes ,
T13343 29113-29115 NNP denotes CA
T13344 29115-29116 -RRB- denotes )
T13345 29118-29119 DT denotes A
T13346 29120-29129 NNP denotes Bio-Plex™
T13347 29130-29133 CD denotes 200
T13348 29134-29141 NN denotes readout
T13349 29142-29148 NN denotes System
T13350 29149-29152 VB denotes was
T13351 29153-29157 VB denotes used
T13352 29158-29159 -LRB- denotes (
T13353 29159-29166 JJ denotes Bio-Rad
T13354 29166-29167 -RRB- denotes )
T13355 29167-29168 -COMMA- denotes ,
T13356 29169-29174 WDT denotes which
T13357 29175-29183 VB denotes utilizes
T13358 29184-29192 NNP denotes Luminex®
T13359 29193-29198 NNP denotes xMAP™
T13360 29199-29210 JJ denotes fluorescent
T13361 29211-29221 JJ denotes bead-based
T13362 29222-29232 NN denotes technology
T13363 29233-29234 -LRB- denotes (
T13364 29234-29241 NNP denotes Luminex
T13365 29242-29247 NNP denotes Corp.
T13366 29247-29248 -COMMA- denotes ,
T13367 29249-29255 NNP denotes Austin
T13368 29255-29256 -RRB- denotes )
T13369 29258-29264 NN denotes Levels
T13370 29265-29269 VB denotes were
T13371 29270-29283 RB denotes automatically
T13372 29284-29294 VB denotes calculated
T13373 29295-29299 IN denotes from
T13374 29300-29308 JJ denotes standard
T13375 29309-29315 NN denotes curves
T13376 29316-29321 VB denotes using
T13377 29322-29330 NNP denotes Bio-Plex
T13378 29331-29338 NNP denotes Manager
T13379 29339-29347 NN denotes software
T13380 29348-29349 -LRB- denotes (
T13381 29349-29356 NN denotes v.4.1.1
T13382 29356-29357 -COMMA- denotes ,
T13383 29358-29365 NNP denotes Bio-Rad
T13384 29365-29366 -RRB- denotes )
T13598 29369-29382 JJ denotes Enzyme-linked
T13599 29383-29396 JJ denotes immunosorbent
T13600 29397-29402 NN denotes assay
T13601 29403-29404 -LRB- denotes (
T13602 29404-29409 NN denotes ELISA
T13603 29409-29410 -RRB- denotes )
T13604 29411-29416 NN denotes ELISA
T13605 29417-29420 VB denotes was
T13606 29421-29430 VB denotes performed
T13607 29431-29433 IN denotes on
T13608 29434-29446 NN denotes supernatants
T13609 29447-29451 IN denotes from
T13610 29452-29462 JJ denotes challenged
T13611 29463-29469 NN denotes Jurkat
T13612 29470-29477 NN denotes T-cells
T13613 29478-29480 TO denotes to
T13614 29481-29489 VB denotes quantify
T13615 29490-29494 NN denotes IL-6
T13616 29494-29495 -COMMA- denotes ,
T13617 29496-29501 NN denotes CXCL8
T13618 29502-29505 CC denotes and
T13619 29506-29509 NN denotes TNF
T13620 29510-29511 -LRB- denotes (
T13621 29511-29513 NN denotes BD
T13622 29514-29520 NN denotes OptEIA
T13623 29521-29526 JJ denotes Human
T13624 29527-29531 NN denotes IL-6
T13625 29532-29537 NNP denotes Elisa
T13626 29538-29541 NNP denotes Set
T13627 29541-29542 -COMMA- denotes ,
T13628 29543-29545 NNP denotes BD
T13629 29546-29552 NNP denotes OptEIA
T13630 29553-29558 NNP denotes Human
T13631 29559-29564 NNP denotes CXCL8
T13632 29565-29570 NNP denotes Elisa
T13633 29571-29574 NNP denotes Set
T13634 29575-29578 CC denotes and
T13635 29579-29581 NNP denotes BD
T13636 29582-29588 NNP denotes OptEIA
T13637 29589-29594 NNP denotes Human
T13638 29595-29598 NN denotes TNF
T13639 29599-29604 NNP denotes Elisa
T13640 29605-29608 NNP denotes Set
T13641 29608-29609 -COMMA- denotes ,
T13642 29610-29621 NNP denotes Biosciences
T13643 29621-29622 -COMMA- denotes ,
T13644 29623-29626 NNP denotes USA
T13645 29626-29627 -RRB- denotes )
T13646 29628-29637 VB denotes according
T13647 29638-29640 TO denotes to
T13648 29641-29644 DT denotes the
T13649 29645-29657 NN denotes manufacturer
T13650 29657-29659 POS denotes 's
T13651 29660-29672 NN denotes instructions
T13652 29674-29681 RB denotes Briefly
T13653 29681-29682 -COMMA- denotes ,
T13654 29683-29689 NN denotes Jurkat
T13655 29690-29697 NN denotes T-cells
T13656 29698-29702 VB denotes were
T13657 29703-29713 VB denotes stimulated
T13658 29714-29718 IN denotes with
T13659 29719-29722 NN denotes PMA
T13660 29723-29724 -LRB- denotes (
T13661 29724-29727 CD denotes 162
T13662 29728-29730 NN denotes nM
T13663 29730-29731 -RRB- denotes )
T13664 29732-29735 IN denotes for
T13665 29736-29737 CD denotes 1
T13666 29738-29739 NN denotes h
T13667 29739-29740 -COMMA- denotes ,
T13668 29741-29752 VB denotes centrifuged
T13669 29753-29754 -LRB- denotes (
T13670 29754-29758 CD denotes 1000
T13671 29759-29760 -RRB- denotes ×
T13672 29761-29762 NN denotes g
T13673 29762-29763 -COMMA- denotes ,
T13674 29764-29765 CD denotes 8
T13675 29766-29769 NN denotes min
T13676 29769-29770 -RRB- denotes )
T13677 29771-29774 CC denotes and
T13678 29775-29778 DT denotes the
T13679 29779-29791 NN denotes supernatants
T13680 29792-29796 VB denotes were
T13681 29797-29806 VB denotes collected
T13682 29807-29810 CC denotes and
T13683 29811-29817 VB denotes stored
T13684 29818-29820 IN denotes at
T13685 29821-29826 NN denotes -80°C
T13686 29827-29832 IN denotes until
T13687 29833-29836 NN denotes use
T13688 29838-29847 VB denotes Following
T13689 29848-29862 NN denotes centrifugation
T13690 29862-29863 -COMMA- denotes ,
T13691 29864-29867 DT denotes the
T13692 29868-29873 NN denotes cells
T13693 29874-29878 VB denotes were
T13694 29879-29890 VB denotes resuspended
T13695 29891-29893 IN denotes in
T13696 29894-29895 CD denotes 1
T13697 29896-29897 NN denotes h
T13698 29898-29902 JJ denotes aged
T13699 29903-29908 NN denotes media
T13700 29908-29909 -COMMA- denotes ,
T13701 29910-29915 WRB denotes where
T13702 29916-29921 NN denotes cells
T13703 29922-29926 VB denotes have
T13704 29927-29931 VB denotes been
T13705 29932-29937 VB denotes grown
T13706 29938-29940 IN denotes in
T13707 29940-29941 -COMMA- denotes ,
T13708 29942-29952 VB denotes containing
T13709 29953-29956 NN denotes PMA
T13710 29958-29961 DT denotes The
T13711 29962-29966 JJ denotes same
T13712 29967-29976 NN denotes procedure
T13713 29977-29980 VB denotes was
T13714 29981-29990 VB denotes performed
T13715 29991-29993 TO denotes to
T13716 29994-30001 VB denotes collect
T13717 30002-30007 NN denotes media
T13718 30008-30013 IN denotes after
T13719 30014-30015 CD denotes 2
T13720 30016-30017 NN denotes h
T13721 30018-30021 CC denotes and
T13722 30022-30023 CD denotes 6
T13723 30024-30025 NN denotes h
T13724 30027-30030 DT denotes The
T13725 30031-30036 JJ denotes final
T13726 30037-30047 NN denotes collection
T13727 30048-30050 IN denotes of
T13728 30051-30056 NN denotes media
T13729 30057-30060 VB denotes was
T13730 30061-30070 VB denotes performed
T13731 30071-30076 IN denotes after
T13732 30077-30079 CD denotes 24
T13733 30080-30081 NN denotes h
T13952 30084-30091 NN denotes Western
T13953 30092-30096 NN denotes blot
T13954 30097-30105 NN denotes analysis
T13955 30106-30115 VB denotes Following
T13956 30116-30127 NN denotes stimulation
T13957 30127-30128 -COMMA- denotes ,
T13958 30129-30135 NN denotes Jurkat
T13959 30136-30143 NN denotes T-cells
T13960 30144-30148 VB denotes were
T13961 30149-30160 VB denotes centrifuged
T13962 30161-30163 IN denotes at
T13963 30164-30168 CD denotes 1000
T13964 30169-30170 SYM denotes ×
T13965 30171-30172 NN denotes g
T13966 30173-30176 IN denotes for
T13967 30177-30178 CD denotes 8
T13968 30179-30182 NN denotes min
T13969 30183-30186 CC denotes and
T13970 30187-30192 VB denotes lysed
T13971 30193-30195 IN denotes on
T13972 30196-30199 NN denotes ice
T13973 30200-30203 IN denotes for
T13974 30204-30205 CD denotes 2
T13975 30206-30207 NN denotes h
T13976 30208-30213 VB denotes using
T13977 30214-30220 NN denotes sodium
T13978 30221-30230 NN denotes hydroxide
T13979 30231-30235 IN denotes with
T13980 30236-30239 DT denotes the
T13981 30240-30248 NN denotes addition
T13982 30249-30251 IN denotes of
T13983 30252-30253 DT denotes a
T13984 30254-30262 NN denotes protease
T13985 30263-30272 NN denotes inhibitor
T13986 30273-30281 NN denotes cocktail
T13987 30282-30283 -LRB- denotes (
T13988 30283-30288 NNP denotes Roche
T13989 30288-30289 -COMMA- denotes ,
T13990 30290-30298 NNP denotes Mannheim
T13991 30298-30299 -RRB- denotes )
T13992 30301-30304 DT denotes The
T13993 30305-30310 NN denotes cells
T13994 30311-30315 VB denotes were
T13995 30316-30323 RB denotes further
T13996 30324-30335 VB denotes centrifuged
T13997 30336-30338 IN denotes at
T13998 30339-30343 CD denotes 8000
T13999 30344-30345 SYM denotes ×
T14000 30346-30347 NN denotes g
T14001 30347-30348 -COMMA- denotes ,
T14002 30349-30352 NN denotes 4°C
T14003 30353-30356 IN denotes for
T14004 30357-30359 CD denotes 10
T14005 30360-30363 NN denotes min
T14006 30364-30367 CC denotes and
T14007 30368-30371 DT denotes the
T14008 30372-30384 NN denotes supernatants
T14009 30385-30389 VB denotes were
T14010 30390-30401 VB denotes transferred
T14011 30402-30404 TO denotes to
T14012 30405-30408 JJ denotes new
T14013 30409-30414 NN denotes tubes
T14014 30416-30427 JJ denotes Cytoplasmic
T14015 30428-30436 NN denotes proteins
T14016 30437-30438 -LRB- denotes (
T14017 30438-30440 CD denotes ~8
T14018 30441-30443 NN denotes μg
T14019 30443-30444 -RRB- denotes )
T14020 30445-30449 VB denotes were
T14021 30450-30459 VB denotes separated
T14022 30460-30462 IN denotes by
T14023 30463-30471 NN denotes SDS-PAGE
T14024 30472-30473 -LRB- denotes (
T14025 30473-30475 CD denotes 10
T14026 30475-30476 NN denotes %
T14027 30476-30477 -RRB- denotes )
T14028 30478-30486 VB denotes followed
T14029 30487-30489 IN denotes by
T14030 30490-30497 JJ denotes western
T14031 30498-30506 NN denotes blotting
T14032 30507-30512 VB denotes using
T14033 30513-30522 JJ denotes anti-IκBβ
T14034 30522-30523 -COMMA- denotes ,
T14035 30524-30535 NN denotes phospho-PKC
T14036 30536-30537 -LRB- denotes (
T14037 30537-30540 NN denotes pan
T14038 30540-30541 -RRB- denotes )
T14039 30541-30542 -LRB- denotes (
T14040 30542-30543 SYM denotes ζ
T14041 30544-30550 NN denotes Thr410
T14042 30550-30551 -RRB- denotes )
T14043 30551-30552 -LRB- denotes (
T14044 30552-30558 NN denotes 190D10
T14045 30558-30559 -RRB- denotes )
T14046 30559-30560 -COMMA- denotes ,
T14047 30561-30571 NN denotes anti-Bcl10
T14048 30572-30573 -LRB- denotes (
T14049 30573-30577 NNP denotes Cell
T14050 30578-30588 NNP denotes Signalling
T14051 30589-30599 NNP denotes Technology
T14052 30599-30600 -COMMA- denotes ,
T14053 30601-30607 NNP denotes Boston
T14054 30607-30608 -RRB- denotes )
T14055 30609-30612 CC denotes and
T14056 30613-30623 NN denotes beta-actin
T14057 30624-30625 -LRB- denotes (
T14058 30625-30630 NNP denotes Abcam
T14059 30630-30631 -COMMA- denotes ,
T14060 30632-30641 NNP denotes Cambridge
T14061 30641-30642 -RRB- denotes )
T14062 30644-30653 NN denotes Detection
T14063 30654-30657 VB denotes was
T14064 30658-30667 VB denotes performed
T14065 30668-30677 VB denotes following
T14066 30678-30688 NN denotes incubation
T14067 30689-30693 IN denotes with
T14068 30694-30698 NNP denotes ECL™
T14069 30699-30710 NNP denotes Anti-rabbit
T14070 30711-30714 NN denotes IgG
T14071 30714-30715 -COMMA- denotes ,
T14072 30716-30727 NN denotes horseradish
T14073 30728-30738 NN denotes peroxidase
T14074 30739-30745 VB denotes linked
T14075 30746-30751 JJ denotes whole
T14076 30752-30762 NN denotes antibodies
T14077 30763-30764 -LRB- denotes (
T14078 30764-30772 NNP denotes Amersham
T14079 30773-30784 NNP denotes Biosciences
T14080 30784-30785 -COMMA- denotes ,
T14081 30786-30801 NNP denotes Buckinghamshire
T14082 30801-30802 -RRB- denotes )
T14083 30803-30806 CC denotes and
T14084 30807-30816 VB denotes developed
T14085 30817-30822 VB denotes using
T14086 30823-30827 NNP denotes ECL™
T14087 30828-30835 NNP denotes Western
T14088 30836-30844 NNP denotes Blotting
T14089 30845-30854 NNP denotes Detection
T14090 30855-30863 NNP denotes Reagents
T14091 30864-30865 -LRB- denotes (
T14092 30865-30867 NNP denotes GE
T14093 30868-30878 NNP denotes Healthcare
T14094 30878-30879 -COMMA- denotes ,
T14095 30880-30882 NNP denotes UK
T14096 30882-30883 -RRB- denotes )
T14306 30886-30889 NN denotes RNA
T14307 30890-30900 NN denotes extraction
T14308 30901-30907 NN denotes Jurkat
T14309 30908-30915 NN denotes T-cells
T14310 30916-30920 VB denotes were
T14311 30921-30928 VB denotes treated
T14312 30929-30933 IN denotes with
T14313 30934-30939 NN denotes NF-κB
T14314 30939-30940 -COMMA- denotes ,
T14315 30941-30944 NN denotes JNK
T14316 30945-30948 CC denotes and
T14317 30949-30952 NN denotes PKC
T14318 30953-30963 NN denotes inhibitors
T14319 30964-30967 IN denotes for
T14320 30968-30969 CD denotes 2
T14321 30970-30971 NN denotes h
T14322 30972-30974 IN denotes in
T14323 30975-30981 JJ denotes 6-well
T14324 30982-30988 NN denotes plates
T14325 30989-30997 VB denotes followed
T14326 30998-31000 IN denotes by
T14327 31001-31012 NN denotes stimulation
T14328 31013-31017 IN denotes with
T14329 31018-31021 CD denotes 162
T14330 31022-31024 NN denotes nM
T14331 31025-31028 NN denotes PMA
T14332 31029-31032 IN denotes for
T14333 31033-31035 CD denotes 24
T14334 31036-31037 NN denotes h
T14335 31039-31041 IN denotes At
T14336 31042-31050 VB denotes sampling
T14337 31051-31054 DT denotes the
T14338 31055-31060 NN denotes cells
T14339 31061-31065 VB denotes were
T14340 31066-31074 VB denotes pelleted
T14341 31075-31083 VB denotes followed
T14342 31084-31086 IN denotes by
T14343 31087-31090 NN denotes RNA
T14344 31091-31101 NN denotes extraction
T14345 31102-31107 VB denotes using
T14346 31108-31111 CD denotes 100
T14347 31112-31114 NN denotes μl
T14348 31115-31126 NN denotes TRI-reagent
T14349 31127-31128 -LRB- denotes (
T14350 31128-31133 NNP denotes Sigma
T14351 31133-31134 -COMMA- denotes ,
T14352 31135-31138 NNP denotes USA
T14353 31138-31139 -RRB- denotes )
T14354 31141-31145 DT denotes This
T14355 31146-31149 VB denotes was
T14356 31150-31158 VB denotes followed
T14357 31159-31161 IN denotes by
T14358 31162-31170 NN denotes addition
T14359 31171-31173 IN denotes of
T14360 31174-31177 CD denotes 100
T14361 31178-31180 NN denotes μl
T14362 31181-31206 NN denotes chloroform/isoamylalcohol
T14363 31207-31208 -LRB- denotes (
T14364 31208-31212 CD denotes 24/1
T14365 31212-31213 -RRB- denotes )
T14366 31215-31218 DT denotes The
T14367 31219-31228 NN denotes solutions
T14368 31229-31233 VB denotes were
T14369 31234-31239 VB denotes mixed
T14370 31240-31242 IN denotes by
T14371 31243-31252 VB denotes vortexing
T14372 31253-31261 VB denotes followed
T14373 31262-31264 IN denotes by
T14374 31265-31279 NN denotes centrifugation
T14375 31280-31282 IN denotes at
T14376 31283-31289 CD denotes 12,000
T14377 31290-31293 NN denotes rpm
T14378 31294-31297 IN denotes for
T14379 31298-31300 CD denotes 15
T14380 31301-31304 NN denotes min
T14381 31305-31307 IN denotes at
T14382 31308-31312 NNP denotes 4°C.
T14383 31313-31316 DT denotes The
T14384 31317-31322 JJ denotes upper
T14385 31323-31328 NN denotes phase
T14386 31329-31332 VB denotes was
T14387 31333-31344 VB denotes transferred
T14388 31345-31347 TO denotes to
T14389 31348-31349 DT denotes a
T14390 31350-31353 JJ denotes new
T14391 31354-31358 NN denotes tube
T14392 31359-31367 VB denotes followed
T14393 31368-31370 IN denotes by
T14394 31371-31379 NN denotes addition
T14395 31380-31382 IN denotes of
T14396 31383-31386 CD denotes 100
T14397 31387-31389 NN denotes μl
T14398 31390-31402 NN denotes iso-propanol
T14399 31403-31406 CC denotes and
T14400 31407-31416 VB denotes incubated
T14401 31417-31419 IN denotes at
T14402 31420-31424 NN denotes room
T14403 31425-31436 NN denotes temperature
T14404 31437-31440 IN denotes for
T14405 31441-31443 CD denotes 10
T14406 31444-31447 NN denotes min
T14407 31449-31452 NN denotes RNA
T14408 31453-31456 VB denotes was
T14409 31457-31461 RB denotes then
T14410 31462-31470 VB denotes pelleted
T14411 31471-31473 IN denotes by
T14412 31474-31488 NN denotes centrifugation
T14413 31489-31491 IN denotes at
T14414 31492-31498 CD denotes 12,000
T14415 31499-31502 NN denotes rpm
T14416 31503-31506 IN denotes for
T14417 31507-31509 CD denotes 15
T14418 31510-31513 NN denotes min
T14419 31514-31516 IN denotes at
T14420 31517-31520 NN denotes 4°C
T14421 31521-31524 CC denotes and
T14422 31525-31531 VB denotes washed
T14423 31532-31536 IN denotes with
T14424 31537-31539 CD denotes 70
T14425 31539-31540 NN denotes %
T14426 31541-31548 NN denotes ethanol
T14427 31550-31553 DT denotes The
T14428 31554-31557 NN denotes RNA
T14429 31558-31564 NN denotes pellet
T14430 31565-31568 VB denotes was
T14431 31569-31578 VB denotes dissolved
T14432 31579-31581 IN denotes in
T14433 31582-31584 CD denotes 25
T14434 31585-31587 NN denotes μl
T14435 31588-31593 NN denotes RNase
T14436 31594-31598 JJ denotes free
T14437 31599-31604 NN denotes water
T14438 31605-31608 CC denotes and
T14439 31609-31612 DT denotes the
T14440 31613-31618 NN denotes yield
T14441 31619-31622 CC denotes and
T14442 31623-31628 NN denotes ratio
T14443 31629-31630 -LRB- denotes (
T14444 31630-31639 NN denotes A260/A280
T14445 31639-31640 -RRB- denotes )
T14446 31641-31644 VB denotes was
T14447 31645-31655 VB denotes determined
T14448 31656-31661 VB denotes using
T14449 31662-31669 NNP denotes NanoVue
T14450 31670-31671 -LRB- denotes (
T14451 31671-31673 NNP denotes GE
T14452 31674-31684 NNP denotes Healthcare
T14453 31684-31685 -COMMA- denotes ,
T14454 31686-31688 NNP denotes UK
T14455 31688-31689 -RRB- denotes )
T14456 31691-31694 DT denotes The
T14457 31695-31702 NN denotes samples
T14458 31703-31707 VB denotes were
T14459 31708-31714 VB denotes stored
T14460 31715-31717 IN denotes at
T14461 31718-31723 NN denotes -80°C
T14462 31724-31729 IN denotes until
T14463 31730-31737 JJ denotes further
T14464 31738-31741 NN denotes use
T14699 31744-31751 JJ denotes Reverse
T14700 31752-31765 NN denotes transcription
T14701 31766-31778 JJ denotes quantitative
T14702 31779-31782 NN denotes PCR
T14703 31783-31784 -LRB- denotes (
T14704 31784-31791 NN denotes RT-qPCR
T14705 31791-31792 -RRB- denotes )
T14706 31793-31800 NN denotes RT-qPCR
T14707 31801-31804 VB denotes was
T14708 31805-31809 VB denotes used
T14709 31810-31812 TO denotes to
T14710 31813-31822 VB denotes determine
T14711 31823-31827 NN denotes gene
T14712 31828-31838 NN denotes expression
T14713 31839-31845 NN denotes levels
T14714 31846-31848 IN denotes of
T14715 31849-31853 NN denotes il-6
T14716 31854-31857 CC denotes and
T14717 31858-31863 NN denotes cxcl8
T14718 31864-31866 IN denotes in
T14719 31867-31875 NN denotes response
T14720 31876-31878 TO denotes to
T14721 31879-31882 NN denotes PMA
T14722 31883-31892 VB denotes following
T14723 31893-31903 NN denotes inhibition
T14724 31904-31906 IN denotes of
T14725 31907-31912 NN denotes NF-κB
T14726 31912-31913 -COMMA- denotes ,
T14727 31914-31917 NN denotes JNK
T14728 31918-31921 CC denotes and
T14729 31922-31925 NN denotes PKC
T14730 31927-31930 DT denotes The
T14731 31931-31940 VB denotes following
T14732 31941-31947 NN denotes primer
T14733 31948-31957 NN denotes sequences
T14734 31958-31962 VB denotes were
T14735 31963-31967 VB denotes used
T14736 31967-31968 -COMMA- denotes ,
T14737 31969-31973 NN denotes il-6
T14738 31973-31974 -COLON- denotes :
T14739 31975-31983 JJ denotes forward-
T14740 31984-32008 NN denotes TGTGAAAGCAGCAAAGAGGCACTG
T14741 32008-32009 -COMMA- denotes ,
T14742 32010-32018 NN denotes reverse-
T14743 32019-32043 NN denotes ACAGCTCTGGCTTGTTCCTCACTA
T14744 32043-32044 -COLON- denotes ;
T14745 32045-32050 NN denotes cxcl8
T14746 32050-32051 -COLON- denotes :
T14747 32052-32060 JJ denotes forward-
T14748 32061-32085 NN denotes ACCACACTGCGCCAACACAGAAAT
T14749 32085-32086 -COMMA- denotes ,
T14750 32087-32095 NN denotes reverse-
T14751 32096-32120 NN denotes AAACTTCTCCACAACCCTCTGCAC
T14752 32122-32135 VB denotes Thermocycling
T14753 32136-32146 NN denotes conditions
T14754 32147-32150 IN denotes for
T14755 32151-32155 NN denotes CYBR
T14756 32156-32161 NNP denotes Green
T14757 32162-32163 -LRB- denotes (
T14758 32163-32169 NNP denotes Quanta
T14759 32169-32170 -COMMA- denotes ,
T14760 32171-32174 NNP denotes USA
T14761 32174-32175 -RRB- denotes )
T14762 32176-32185 VB denotes consisted
T14763 32186-32188 IN denotes of
T14764 32189-32190 DT denotes a
T14765 32191-32203 NN denotes denaturation
T14766 32204-32208 NN denotes step
T14767 32209-32212 IN denotes for
T14768 32213-32215 CD denotes 10
T14769 32216-32219 NN denotes min
T14770 32220-32222 IN denotes at
T14771 32223-32225 CD denotes 95
T14772 32226-32228 NN denotes °C
T14773 32229-32237 VB denotes followed
T14774 32238-32240 IN denotes by
T14775 32241-32243 CD denotes 60
T14776 32244-32250 NN denotes cycles
T14777 32251-32253 IN denotes of
T14778 32254-32258 NN denotes 95°C
T14779 32259-32262 IN denotes for
T14780 32263-32265 NN denotes 1s
T14781 32266-32269 CC denotes and
T14782 32270-32274 NN denotes 60°C
T14783 32275-32278 IN denotes for
T14784 32279-32282 CD denotes 30s
T14785 32284-32288 NN denotes Gene
T14786 32289-32299 NN denotes expression
T14787 32300-32303 VB denotes was
T14788 32304-32312 VB denotes analysed
T14789 32313-32318 VB denotes using
T14790 32319-32329 NN denotes Stratagene
T14791 32330-32331 -LRB- denotes (
T14792 32331-32339 NN denotes Mx3000p™
T14793 32339-32340 -RRB- denotes )
T14794 32341-32342 -LRB- denotes (
T14795 32342-32344 NN denotes AH
T14796 32345-32356 NN denotes diagnostics
T14797 32356-32357 -RRB- denotes )
T14798 32359-32362 DT denotes The
T14799 32363-32371 VB denotes obtained
T14800 32372-32374 NN denotes Ct
T14801 32375-32381 NN denotes values
T14802 32382-32386 VB denotes were
T14803 32387-32397 VB denotes normalized
T14804 32398-32405 IN denotes against
T14805 32406-32409 NN denotes 18S
T14806 32411-32420 RB denotes Initially
T14807 32420-32421 -COMMA- denotes ,
T14808 32422-32425 DT denotes all
T14809 32426-32434 VB denotes measured
T14810 32435-32438 NN denotes 18S
T14811 32439-32441 NN denotes Ct
T14812 32442-32448 NN denotes values
T14813 32449-32453 VB denotes were
T14814 32454-32458 VB denotes used
T14815 32459-32461 TO denotes to
T14816 32462-32471 VB denotes calculate
T14817 32472-32473 DT denotes a
T14818 32474-32478 JJ denotes mean
T14819 32479-32481 NN denotes Ct
T14820 32482-32487 NN denotes value
T14821 32488-32492 WDT denotes that
T14822 32493-32496 VB denotes was
T14823 32497-32501 VB denotes used
T14824 32502-32504 TO denotes to
T14825 32505-32514 VB denotes determine
T14826 32515-32518 DT denotes the
T14827 32519-32522 NN denotes ΔCt
T14828 32523-32529 NN denotes values
T14829 32530-32533 IN denotes for
T14830 32534-32538 DT denotes each
T14831 32539-32545 NN denotes sample
T14832 32547-32551 NN denotes Gene
T14833 32552-32562 NN denotes expression
T14834 32563-32571 NN denotes patterns
T14835 32572-32575 IN denotes for
T14836 32576-32580 NN denotes il-6
T14837 32581-32584 CC denotes and
T14838 32585-32590 NN denotes cxcl8
T14839 32591-32595 VB denotes were
T14840 32596-32600 RB denotes then
T14841 32601-32611 VB denotes normalized
T14842 32612-32616 IN denotes with
T14843 32617-32623 NN denotes regard
T14844 32624-32626 TO denotes to
T14845 32627-32630 DT denotes the
T14846 32631-32638 NN denotes samples
T14847 32639-32642 NN denotes 18S
T14848 32643-32646 NNP denotes ΔCt
T14993 32649-32660 JJ denotes Statistical
T14994 32661-32669 NN denotes analysis
T14995 32670-32681 JJ denotes Statistical
T14996 32682-32693 JJ denotes significant
T14997 32694-32705 NN denotes differences
T14998 32706-32710 VB denotes were
T14999 32711-32721 VB denotes determined
T15000 32722-32727 VB denotes using
T15001 32728-32738 JJ denotes two-tailed
T15002 32739-32746 NN denotes Student
T15003 32746-32748 POS denotes 's
T15004 32749-32755 NN denotes t-test
T15005 32756-32757 -LRB- denotes (
T15006 32757-32759 NN denotes *p
T15007 32760-32761 SYM denotes <
T15008 32762-32766 CD denotes 0.05
T15009 32766-32767 -COLON- denotes ;
T15010 32768-32771 NN denotes **p
T15011 32772-32773 SYM denotes <
T15012 32774-32778 CD denotes 0.01
T15013 32778-32779 -COLON- denotes ;
T15014 32780-32784 NN denotes ***p
T15015 32785-32786 SYM denotes <
T15016 32787-32792 CD denotes 0.001
T15017 32792-32793 -RRB- denotes )
R10311 T12824 T12823 arg1Of culturing,Cell
R10312 T12824 T12825 arg1Of culturing,","
R10313 T12825 T12827 arg1Of ",",and
R10314 T12826 T12825 arg2Of transfection,","
R10315 T12828 T12827 arg2Of stimulation,and
R10316 T12830 T12829 arg1Of T-cells,Jurkat
R10317 T12830 T12831 arg1Of T-cells,(
R10318 T12830 T12839 arg1Of T-cells,were
R10319 T12830 T12840 arg2Of T-cells,maintained
R10320 T12830 T12883 arg2Of T-cells,incubated
R10321 T12833 T12832 arg1Of type,wild
R10322 T12833 T12834 arg1Of type,and
R10323 T12834 T12831 arg2Of and,(
R10324 T12836 T12834 arg2Of deficient-,and
R10325 T12836 T12835 arg1Of deficient-,TCR
R10326 T12836 T12837 arg1Of deficient-,TCR-/-
R10327 T12838 T12831 arg3Of ),(
R10328 T12840 T12841 arg1Of maintained,in
R10329 T12840 T12882 arg1Of maintained,and
R10330 T12842 T12843 arg1Of 90,%
R10331 T12846 T12842 arg1Of medium,90
R10332 T12846 T12844 arg1Of medium,RPMI
R10333 T12846 T12845 arg1Of medium,1640
R10334 T12846 T12847 arg1Of medium,(
R10335 T12846 T12853 arg1Of medium,with
R10336 T12846 T12868 arg1Of medium,(
R10337 T12846 T12873 arg1Of medium,and
R10338 T12849 T12847 arg2Of laboratories,(
R10339 T12849 T12848 arg1Of laboratories,PAA
R10340 T12849 T12850 arg1Of laboratories,","
R10341 T12851 T12850 arg2Of Austria,","
R10342 T12852 T12847 arg3Of ),(
R10343 T12854 T12855 arg1Of 1.5,mM
R10344 T12856 T12854 arg1Of L-glutamine,1.5
R10345 T12856 T12857 arg1Of L-glutamine,(
R10346 T12856 T12862 arg1Of L-glutamine,","
R10347 T12858 T12857 arg2Of Invitrogen,(
R10348 T12858 T12859 arg1Of Invitrogen,","
R10349 T12858 T12860 arg1Of Invitrogen,USA
R10350 T12861 T12857 arg3Of ),(
R10351 T12862 T12853 arg2Of ",",with
R10352 T12864 T12863 arg1Of %,10
R10353 T12865 T12864 arg1Of foetal,%
R10354 T12867 T12862 arg2Of serum,","
R10355 T12867 T12865 arg1Of serum,foetal
R10356 T12867 T12866 arg1Of serum,bovine
R10357 T12869 T12868 arg2Of Invitrogen,(
R10358 T12869 T12870 arg1Of Invitrogen,","
R10359 T12871 T12870 arg2Of USA,","
R10360 T12872 T12868 arg3Of ),(
R10361 T12873 T12841 arg2Of and,in
R10362 T12874 T12875 arg1Of 1,%
R10363 T12876 T12873 arg2Of antibiotic-antimycotic,and
R10364 T12876 T12874 arg1Of antibiotic-antimycotic,1
R10365 T12876 T12877 arg1Of antibiotic-antimycotic,(
R10366 T12878 T12877 arg2Of Invitrogen,(
R10367 T12878 T12879 arg1Of Invitrogen,","
R10368 T12880 T12879 arg2Of USA,","
R10369 T12881 T12877 arg3Of ),(
R10370 T12882 T12839 arg2Of and,were
R10371 T12883 T12882 arg2Of incubated,and
R10372 T12883 T12884 arg1Of incubated,in
R10373 T12887 T12884 arg2Of environment,in
R10374 T12887 T12885 arg1Of environment,a
R10375 T12887 T12886 arg1Of environment,stable
R10376 T12887 T12888 arg1Of environment,of
R10377 T12887 T12892 arg1Of environment,at
R10378 T12889 T12890 arg1Of 5,%
R10379 T12891 T12888 arg2Of CO2,of
R10380 T12891 T12889 arg1Of CO2,5
R10381 T12893 T12892 arg2Of 37°C,at
R10382 T12895 T12894 arg1Of cells,The
R10383 T12895 T12896 arg1Of cells,were
R10384 T12895 T12897 arg2Of cells,centrifuged
R10385 T12895 T12906 arg1Of cells,resuspended
R10386 T12897 T12896 arg2Of centrifuged,were
R10387 T12897 T12898 arg1Of centrifuged,at
R10388 T12897 T12905 arg1Of centrifuged,and
R10389 T12901 T12898 arg2Of g,at
R10390 T12901 T12899 arg1Of g,1000
R10391 T12901 T12900 arg1Of g,×
R10392 T12901 T12902 arg1Of g,for
R10393 T12904 T12902 arg2Of min,for
R10394 T12904 T12903 arg1Of min,8
R10395 T12906 T12905 arg2Of resuspended,and
R10396 T12906 T12907 arg1Of resuspended,in
R10397 T12906 T12910 arg1Of resuspended,to
R10398 T12909 T12907 arg2Of media,in
R10399 T12909 T12908 arg1Of media,fresh
R10400 T12914 T12910 arg2Of density,to
R10401 T12914 T12911 arg1Of density,a
R10402 T12914 T12912 arg1Of density,final
R10403 T12914 T12913 arg1Of density,cell
R10404 T12914 T12915 arg1Of density,of
R10405 T12916 T12917 arg1Of 1.6,×
R10406 T12918 T12917 arg2Of 107,×
R10407 T12919 T12915 arg2Of cells/ml,of
R10408 T12919 T12916 arg1Of cells/ml,1.6
R10409 T12919 T12918 arg1Of cells/ml,107
R10410 T12919 T12920 arg1Of cells/ml,in
R10411 T12923 T12920 arg2Of plate,in
R10412 T12923 T12921 arg1Of plate,a
R10413 T12923 T12922 arg1Of plate,24-well
R10414 T12925 T12924 arg1Of plasmid,Reporter
R10415 T12925 T12926 arg1Of plasmid,(
R10416 T12925 T12937 arg1Of plasmid,","
R10417 T12927 T12926 arg2Of pNFκB-Luc,(
R10418 T12927 T12928 arg1Of pNFκB-Luc,","
R10419 T12927 T12934 arg1Of pNFκB-Luc,","
R10420 T12931 T12930 arg2Of PMA,(
R10421 T12932 T12930 arg3Of ),(
R10422 T12933 T12928 arg2Of -TA-Luc,","
R10423 T12933 T12929 arg1Of -TA-Luc,pAP1
R10424 T12933 T12930 arg1Of -TA-Luc,(
R10425 T12935 T12934 arg2Of pNFκB-SEAP,","
R10426 T12936 T12926 arg3Of ),(
R10427 T12937 T12944 arg1Of ",",(
R10428 T12937 T12949 arg1Of ",",and
R10429 T12940 T12937 arg2Of plasmid,","
R10430 T12940 T12938 arg1Of plasmid,internal
R10431 T12940 T12939 arg1Of plasmid,control
R10432 T12940 T12941 arg1Of plasmid,(
R10433 T12942 T12941 arg2Of pRL,(
R10434 T12943 T12941 arg3Of ),(
R10435 T12945 T12944 arg2Of Promega,(
R10436 T12945 T12946 arg1Of Promega,","
R10437 T12945 T12947 arg1Of Promega,USA
R10438 T12948 T12944 arg3Of ),(
R10439 T12949 T12957 arg1Of and,were
R10440 T12949 T12958 arg2Of and,added
R10441 T12950 T12949 arg2Of lipofectamine,and
R10442 T12950 T12951 arg1Of lipofectamine,2000
R10443 T12950 T12952 arg1Of lipofectamine,(
R10444 T12953 T12952 arg2Of Invitrogen,(
R10445 T12953 T12954 arg1Of Invitrogen,","
R10446 T12955 T12954 arg2Of USA,","
R10447 T12956 T12952 arg3Of ),(
R10448 T12958 T12957 arg2Of added,were
R10449 T12958 T12959 arg1Of added,to
R10450 T12958 T12962 arg1Of added,at
R10451 T12958 T12971 arg1Of added,","
R10452 T12958 T12972 arg1Of added,respectively
R10453 T12960 T12959 arg2Of each,to
R10454 T12962 T12961 arg1Of at,well
R10455 T12963 T12964 arg1Of 0.54,μg/well
R10456 T12963 T12965 arg1Of 0.54,","
R10457 T12965 T12962 arg2Of ",",at
R10458 T12966 T12967 arg1Of 0.06,μg/well
R10459 T12966 T12968 arg1Of 0.06,and
R10460 T12969 T12968 arg2Of 1.5,and
R10461 T12970 T12965 arg2Of μl/well,","
R10462 T12970 T12966 arg1Of μl/well,0.06
R10463 T12970 T12969 arg1Of μl/well,1.5
R10464 T12977 T12976 arg1Of plasmid,reporter
R10465 T12977 T12978 arg1Of plasmid,and
R10466 T12978 T12975 arg1Of and,the
R10467 T12978 T12980 arg1Of and,were
R10468 T12978 T12981 arg2Of and,mixed
R10469 T12979 T12978 arg2Of pRL,and
R10470 T12981 T12973 arg1Of mixed,Initially
R10471 T12981 T12974 arg1Of mixed,","
R10472 T12981 T12980 arg2Of mixed,were
R10473 T12981 T12982 arg1Of mixed,separately
R10474 T12981 T12983 arg1Of mixed,with
R10475 T12981 T12985 arg1Of mixed,(
R10476 T12984 T12983 arg2Of OptiMEM,with
R10477 T12986 T12985 arg2Of Gibco,(
R10478 T12986 T12987 arg1Of Gibco,","
R10479 T12986 T12988 arg1Of Gibco,USA
R10480 T12989 T12985 arg3Of ),(
R10481 T12992 T12990 arg2Of min,After
R10482 T12992 T12991 arg1Of min,5
R10483 T12992 T12993 arg1Of min,of
R10484 T12992 T12995 arg1Of min,at
R10485 T12994 T12993 arg2Of incubation,of
R10486 T12997 T12995 arg2Of temperature,at
R10487 T12997 T12996 arg1Of temperature,room
R10488 T12999 T13000 arg1Of lipofectamine,2000
R10489 T12999 T13001 arg1Of lipofectamine,was
R10490 T12999 T13002 arg2Of lipofectamine,added
R10491 T13002 T13001 arg2Of added,was
R10492 T13002 T13003 arg1Of added,and
R10493 T13003 T12990 arg1Of and,After
R10494 T13003 T12998 arg1Of and,","
R10495 T13005 T13004 arg1Of mixture,the
R10496 T13005 T13006 arg1Of mixture,was
R10497 T13005 T13007 arg2Of mixture,incubated
R10498 T13007 T13003 arg2Of incubated,and
R10499 T13007 T13006 arg2Of incubated,was
R10500 T13007 T13008 arg1Of incubated,further
R10501 T13007 T13009 arg1Of incubated,for
R10502 T13007 T13012 arg1Of incubated,at
R10503 T13011 T13009 arg2Of min,for
R10504 T13011 T13010 arg1Of min,20
R10505 T13014 T13012 arg2Of temperature,at
R10506 T13014 T13013 arg1Of temperature,room
R10507 T13016 T13015 arg1Of transfection,The
R10508 T13016 T13017 arg1Of transfection,was
R10509 T13016 T13018 arg2Of transfection,allowed
R10510 T13016 T13020 arg1Of transfection,proceed
R10511 T13018 T13017 arg2Of allowed,was
R10512 T13018 T13040 arg2Of allowed,added
R10513 T13020 T13018 arg3Of proceed,allowed
R10514 T13020 T13019 arg1Of proceed,to
R10515 T13020 T13021 arg1Of proceed,overnight
R10516 T13020 T13022 arg1Of proceed,at
R10517 T13023 T13022 arg2Of 37°C,at
R10518 T13023 T13024 arg1Of 37°C,","
R10519 T13023 T13025 arg2Of 37°C,after
R10520 T13023 T13026 arg1Of 37°C,which
R10521 T13029 T13028 arg1Of cells,the
R10522 T13029 T13030 arg1Of cells,were
R10523 T13029 T13031 arg2Of cells,centrifuged
R10524 T13031 T13025 arg1Of centrifuged,after
R10525 T13031 T13027 arg1Of centrifuged,","
R10526 T13031 T13030 arg2Of centrifuged,were
R10527 T13034 T13035 arg2Of media,removed
R10528 T13034 T13036 arg1Of media,and
R10529 T13036 T13033 arg1Of and,the
R10530 T13036 T13040 arg1Of and,added
R10531 T13039 T13036 arg2Of media,and
R10532 T13039 T13037 arg1Of media,fresh
R10533 T13039 T13038 arg1Of media,pre-warmed
R10534 T13040 T13032 arg1Of added,","
R10535 T13042 T13041 arg1Of cells,The
R10536 T13042 T13043 arg1Of cells,were
R10537 T13042 T13044 arg1Of cells,pre-incubated
R10538 T13042 T13053 arg2Of cells,stimulated
R10539 T13044 T13045 arg1Of pre-incubated,with
R10540 T13044 T13052 arg1Of pre-incubated,and
R10541 T13046 T13047 arg1Of NF-κB,","
R10542 T13047 T13049 arg1Of ",",and
R10543 T13048 T13047 arg2Of JNK,","
R10544 T13049 T13045 arg2Of and,with
R10545 T13051 T13049 arg2Of inhibitors,and
R10546 T13051 T13050 arg1Of inhibitors,PKC
R10547 T13052 T13043 arg2Of and,were
R10548 T13053 T13052 arg2Of stimulated,and
R10549 T13053 T13054 arg1Of stimulated,in
R10550 T13056 T13054 arg2Of plates,in
R10551 T13056 T13055 arg1Of plates,24-well
R10552 T13056 T13057 arg1Of plates,with
R10553 T13059 T13057 arg2Of concentrations,with
R10554 T13059 T13058 arg1Of concentrations,different
R10555 T13059 T13060 arg1Of concentrations,of
R10556 T13061 T13062 arg1Of PMA,","
R10557 T13062 T13067 arg1Of ",",and
R10558 T13066 T13062 arg2Of MG1655,","
R10559 T13066 T13063 arg1Of MG1655,HK
R10560 T13066 T13064 arg1Of MG1655,E.
R10561 T13066 T13065 arg1Of MG1655,coli
R10562 T13067 T13060 arg2Of and,of
R10563 T13069 T13068 arg1Of Ionophore,Calcium
R10564 T13070 T13067 arg2Of A23187,and
R10565 T13070 T13069 arg1Of A23187,Ionophore
R10566 T13072 T13071 arg1Of cells,The
R10567 T13072 T13073 arg1Of cells,were
R10568 T13072 T13074 arg2Of cells,lysed
R10569 T13074 T13073 arg2Of lysed,were
R10570 T13074 T13075 arg1Of lysed,and
R10571 T13077 T13076 arg1Of activity,luciferase
R10572 T13077 T13078 arg1Of activity,(
R10573 T13077 T13083 arg1Of activity,was
R10574 T13077 T13084 arg2Of activity,measured
R10575 T13079 T13080 arg1Of NF-κB,and
R10576 T13080 T13078 arg2Of and,(
R10577 T13081 T13080 arg2Of AP-1,and
R10578 T13082 T13078 arg3Of ),(
R10579 T13084 T13075 arg2Of measured,and
R10580 T13084 T13083 arg2Of measured,was
R10581 T13085 T13084 arg3Of using,measured
R10582 T13085 T13091 arg1Of using,(
R10583 T13085 T13096 arg1Of using,according
R10584 T13085 T13102 arg1Of using,on
R10585 T13090 T13085 arg2Of system,using
R10586 T13090 T13086 arg1Of system,the
R10587 T13090 T13087 arg1Of system,Dual-Luciferase®
R10588 T13090 T13088 arg1Of system,reporter
R10589 T13090 T13089 arg1Of system,assay
R10590 T13092 T13091 arg2Of Promega,(
R10591 T13092 T13093 arg1Of Promega,","
R10592 T13092 T13094 arg1Of Promega,USA
R10593 T13095 T13091 arg3Of ),(
R10594 T13097 T13096 arg2Of to,according
R10595 T13099 T13098 arg1Of manufacturer,the
R10596 T13099 T13100 arg2Of manufacturer,'s
R10597 T13101 T13097 arg2Of instructions,to
R10598 T13101 T13100 arg1Of instructions,'s
R10599 T13106 T13102 arg2Of luminometer,on
R10600 T13106 T13103 arg1Of luminometer,a
R10601 T13106 T13104 arg1Of luminometer,TD
R10602 T13106 T13105 arg1Of luminometer,20/20
R10603 T13106 T13107 arg1Of luminometer,(
R10604 T13109 T13107 arg2Of Designs,(
R10605 T13109 T13108 arg1Of Designs,Turner
R10606 T13109 T13110 arg1Of Designs,","
R10607 T13111 T13110 arg2Of Sunnyvale,","
R10608 T13111 T13112 arg1Of Sunnyvale,","
R10609 T13113 T13112 arg2Of CA,","
R10610 T13114 T13107 arg3Of ),(
R10611 T13117 T13115 arg2Of phosphatase,Secreted
R10612 T13117 T13116 arg1Of phosphatase,alkaline
R10613 T13117 T13118 arg1Of phosphatase,(
R10614 T13117 T13127 modOf phosphatase,were
R10615 T13119 T13118 arg2Of NFκB-SEAP,(
R10616 T13119 T13120 arg1Of NFκB-SEAP,","
R10617 T13119 T13123 arg1Of NFκB-SEAP,","
R10618 T13122 T13120 arg2Of 4a,","
R10619 T13122 T13121 arg1Of 4a,figure
R10620 T13124 T13123 arg2Of b,","
R10621 T13125 T13118 arg3Of ),(
R10622 T13126 T13127 arg1Of levels,were
R10623 T13126 T13128 arg2Of levels,measured
R10624 T13128 T13127 arg2Of measured,were
R10625 T13129 T13128 arg3Of using,measured
R10626 T13129 T13135 arg1Of using,(
R10627 T13133 T13130 arg1Of Detection,Great
R10628 T13133 T13131 arg1Of Detection,EscAPe™
R10629 T13133 T13132 arg1Of Detection,SEAP
R10630 T13134 T13129 arg2Of Kit,using
R10631 T13134 T13133 arg1Of Kit,Detection
R10632 T13136 T13135 arg2Of Clontech,(
R10633 T13136 T13137 arg1Of Clontech,","
R10634 T13136 T13138 arg1Of Clontech,USA
R10635 T13139 T13135 arg3Of ),(
R10731 T13304 T13302 arg1Of assay,Multiplex
R10732 T13304 T13303 arg1Of assay,cytokine
R10733 T13305 T13306 arg1Of Quantification,of
R10734 T13305 T13322 arg1Of Quantification,was
R10735 T13305 T13323 arg2Of Quantification,performed
R10736 T13308 T13306 arg2Of levels,of
R10737 T13308 T13307 arg1Of levels,the
R10738 T13308 T13309 arg1Of levels,of
R10739 T13311 T13312 arg1Of IL-2,","
R10740 T13312 T13310 arg1Of ",",cytokines
R10741 T13312 T13314 arg1Of ",",","
R10742 T13313 T13312 arg2Of IL-6,","
R10743 T13314 T13316 arg1Of ",",and
R10744 T13315 T13314 arg2Of IL-10,","
R10745 T13316 T13318 arg1Of and,and
R10746 T13317 T13316 arg2Of TNF,and
R10747 T13318 T13309 arg2Of and,of
R10748 T13321 T13318 arg2Of CXCL8,and
R10749 T13321 T13319 arg1Of CXCL8,the
R10750 T13321 T13320 arg1Of CXCL8,chemokine
R10751 T13323 T13322 arg2Of performed,was
R10752 T13323 T13324 arg1Of performed,on
R10753 T13326 T13324 arg2Of supernatants,on
R10754 T13326 T13325 arg1Of supernatants,culture
R10755 T13326 T13327 arg1Of supernatants,using
R10756 T13331 T13327 arg2Of kits,using
R10757 T13331 T13328 arg1Of kits,multiplexed
R10758 T13331 T13329 arg1Of kits,biomarker
R10759 T13331 T13330 arg1Of kits,immunoassay
R10760 T13331 T13332 arg1Of kits,according
R10761 T13331 T13337 arg1Of kits,(
R10762 T13333 T13332 arg2Of to,according
R10763 T13334 T13335 arg2Of manufacturer,'s
R10764 T13336 T13333 arg2Of instructions,to
R10765 T13336 T13335 arg1Of instructions,'s
R10766 T13339 T13337 arg2Of Laboratories,(
R10767 T13339 T13338 arg1Of Laboratories,Bio-Rad
R10768 T13339 T13340 arg1Of Laboratories,","
R10769 T13341 T13340 arg2Of Hercules,","
R10770 T13341 T13342 arg1Of Hercules,","
R10771 T13343 T13342 arg2Of CA,","
R10772 T13344 T13337 arg3Of ),(
R10773 T13346 T13347 arg1Of Bio-Plex™,200
R10774 T13349 T13345 arg1Of System,A
R10775 T13349 T13346 arg1Of System,Bio-Plex™
R10776 T13349 T13348 arg1Of System,readout
R10777 T13349 T13350 arg1Of System,was
R10778 T13349 T13351 arg2Of System,used
R10779 T13351 T13350 arg2Of used,was
R10780 T13351 T13352 arg1Of used,(
R10781 T13351 T13355 arg1Of used,","
R10782 T13351 T13356 arg1Of used,which
R10783 T13351 T13357 arg1Of used,utilizes
R10784 T13353 T13352 arg2Of Bio-Rad,(
R10785 T13354 T13352 arg3Of ),(
R10786 T13359 T13358 arg1Of xMAP™,Luminex®
R10787 T13362 T13357 arg2Of technology,utilizes
R10788 T13362 T13359 arg1Of technology,xMAP™
R10789 T13362 T13360 arg1Of technology,fluorescent
R10790 T13362 T13361 arg1Of technology,bead-based
R10791 T13362 T13363 arg1Of technology,(
R10792 T13365 T13363 arg2Of Corp.,(
R10793 T13365 T13364 arg1Of Corp.,Luminex
R10794 T13365 T13366 arg1Of Corp.,","
R10795 T13367 T13366 arg2Of Austin,","
R10796 T13368 T13363 arg3Of ),(
R10797 T13369 T13370 arg1Of Levels,were
R10798 T13369 T13372 arg2Of Levels,calculated
R10799 T13372 T13370 arg2Of calculated,were
R10800 T13372 T13371 arg1Of calculated,automatically
R10801 T13372 T13373 arg1Of calculated,from
R10802 T13375 T13373 arg2Of curves,from
R10803 T13375 T13374 arg1Of curves,standard
R10804 T13375 T13376 arg1Of curves,using
R10805 T13378 T13377 arg1Of Manager,Bio-Plex
R10806 T13379 T13376 arg2Of software,using
R10807 T13379 T13378 arg1Of software,Manager
R10808 T13379 T13380 arg1Of software,(
R10809 T13381 T13380 arg2Of v.4.1.1,(
R10810 T13381 T13382 arg1Of v.4.1.1,","
R10811 T13383 T13382 arg2Of Bio-Rad,","
R10812 T13384 T13380 arg3Of ),(
R10960 T13600 T13598 arg1Of assay,Enzyme-linked
R10961 T13600 T13599 arg1Of assay,immunosorbent
R10962 T13600 T13601 arg1Of assay,(
R10963 T13602 T13601 arg2Of ELISA,(
R10964 T13603 T13601 arg3Of ),(
R10965 T13604 T13605 arg1Of ELISA,was
R10966 T13604 T13606 arg2Of ELISA,performed
R10967 T13606 T13605 arg2Of performed,was
R10968 T13606 T13607 arg1Of performed,on
R10969 T13608 T13607 arg2Of supernatants,on
R10970 T13608 T13609 arg1Of supernatants,from
R10971 T13608 T13613 modOf supernatants,to
R10972 T13612 T13609 arg2Of T-cells,from
R10973 T13612 T13610 arg1Of T-cells,challenged
R10974 T13612 T13611 arg1Of T-cells,Jurkat
R10975 T13614 T13613 arg1Of quantify,to
R10976 T13614 T13646 arg1Of quantify,according
R10977 T13615 T13616 arg1Of IL-6,","
R10978 T13616 T13618 arg1Of ",",and
R10979 T13617 T13616 arg2Of CXCL8,","
R10980 T13618 T13614 arg2Of and,quantify
R10981 T13618 T13620 arg1Of and,(
R10982 T13619 T13618 arg2Of TNF,and
R10983 T13626 T13620 arg2Of Set,(
R10984 T13626 T13621 arg1Of Set,BD
R10985 T13626 T13622 arg1Of Set,OptEIA
R10986 T13626 T13623 arg1Of Set,Human
R10987 T13626 T13624 arg1Of Set,IL-6
R10988 T13626 T13625 arg1Of Set,Elisa
R10989 T13626 T13627 arg1Of Set,","
R10990 T13633 T13628 arg1Of Set,BD
R10991 T13633 T13629 arg1Of Set,OptEIA
R10992 T13633 T13630 arg1Of Set,Human
R10993 T13633 T13631 arg1Of Set,CXCL8
R10994 T13633 T13632 arg1Of Set,Elisa
R10995 T13633 T13634 arg1Of Set,and
R10996 T13637 T13634 arg2Of Human,and
R10997 T13637 T13635 arg1Of Human,BD
R10998 T13637 T13636 arg1Of Human,OptEIA
R10999 T13640 T13627 arg2Of Set,","
R11000 T13640 T13633 arg1Of Set,Set
R11001 T13640 T13637 arg1Of Set,Human
R11002 T13640 T13638 arg1Of Set,TNF
R11003 T13640 T13639 arg1Of Set,Elisa
R11004 T13640 T13641 arg1Of Set,","
R11005 T13642 T13641 arg2Of Biosciences,","
R11006 T13642 T13643 arg1Of Biosciences,","
R11007 T13642 T13644 arg1Of Biosciences,USA
R11008 T13645 T13620 arg3Of ),(
R11009 T13647 T13646 arg2Of to,according
R11010 T13649 T13648 arg1Of manufacturer,the
R11011 T13649 T13650 arg2Of manufacturer,'s
R11012 T13651 T13647 arg2Of instructions,to
R11013 T13651 T13650 arg1Of instructions,'s
R11014 T13655 T13654 arg1Of T-cells,Jurkat
R11015 T13655 T13656 arg1Of T-cells,were
R11016 T13655 T13657 arg2Of T-cells,stimulated
R11017 T13657 T13656 arg2Of stimulated,were
R11018 T13657 T13658 arg1Of stimulated,with
R11019 T13657 T13677 arg1Of stimulated,and
R11020 T13659 T13658 arg2Of PMA,with
R11021 T13659 T13660 arg1Of PMA,(
R11022 T13659 T13664 arg1Of PMA,for
R11023 T13659 T13667 arg1Of PMA,","
R11024 T13659 T13668 arg2Of PMA,centrifuged
R11025 T13659 T13669 arg1Of PMA,(
R11026 T13662 T13660 arg2Of nM,(
R11027 T13662 T13661 arg1Of nM,162
R11028 T13663 T13660 arg3Of ),(
R11029 T13666 T13664 arg2Of h,for
R11030 T13666 T13665 arg1Of h,1
R11031 T13670 T13669 arg2Of 1000,(
R11032 T13670 T13671 arg1Of 1000,×
R11033 T13672 T13671 arg2Of g,×
R11034 T13672 T13673 arg1Of g,","
R11035 T13675 T13673 arg2Of min,","
R11036 T13675 T13674 arg1Of min,8
R11037 T13676 T13669 arg3Of ),(
R11038 T13677 T13652 arg1Of and,Briefly
R11039 T13677 T13653 arg1Of and,","
R11040 T13679 T13678 arg1Of supernatants,the
R11041 T13679 T13680 arg1Of supernatants,were
R11042 T13679 T13681 arg2Of supernatants,collected
R11043 T13679 T13683 arg2Of supernatants,stored
R11044 T13681 T13682 arg1Of collected,and
R11045 T13682 T13677 arg2Of and,and
R11046 T13682 T13680 arg2Of and,were
R11047 T13682 T13686 arg1Of and,until
R11048 T13683 T13682 arg2Of stored,and
R11049 T13683 T13684 arg1Of stored,at
R11050 T13685 T13684 arg2Of -80°C,at
R11051 T13687 T13686 arg2Of use,until
R11052 T13689 T13688 arg2Of centrifugation,Following
R11053 T13692 T13691 arg1Of cells,the
R11054 T13692 T13693 arg1Of cells,were
R11055 T13692 T13694 arg2Of cells,resuspended
R11056 T13694 T13688 arg1Of resuspended,Following
R11057 T13694 T13690 arg1Of resuspended,","
R11058 T13694 T13693 arg2Of resuspended,were
R11059 T13694 T13695 arg1Of resuspended,in
R11060 T13699 T13695 arg2Of media,in
R11061 T13699 T13696 arg1Of media,1
R11062 T13699 T13697 arg1Of media,h
R11063 T13699 T13698 arg1Of media,aged
R11064 T13699 T13700 arg1Of media,","
R11065 T13699 T13701 arg1Of media,where
R11066 T13699 T13707 arg1Of media,","
R11067 T13699 T13708 arg1Of media,containing
R11068 T13702 T13703 arg1Of cells,have
R11069 T13702 T13704 arg1Of cells,been
R11070 T13702 T13705 arg2Of cells,grown
R11071 T13705 T13701 arg2Of grown,where
R11072 T13705 T13703 arg2Of grown,have
R11073 T13705 T13704 arg2Of grown,been
R11074 T13705 T13706 arg1Of grown,in
R11075 T13709 T13708 arg2Of PMA,containing
R11076 T13712 T13710 arg1Of procedure,The
R11077 T13712 T13711 arg1Of procedure,same
R11078 T13712 T13713 arg1Of procedure,was
R11079 T13712 T13714 arg2Of procedure,performed
R11080 T13714 T13713 arg2Of performed,was
R11081 T13716 T13714 arg3Of collect,performed
R11082 T13716 T13715 arg1Of collect,to
R11083 T13716 T13718 arg1Of collect,after
R11084 T13717 T13716 arg2Of media,collect
R11085 T13720 T13719 arg1Of h,2
R11086 T13720 T13721 arg1Of h,and
R11087 T13721 T13718 arg2Of and,after
R11088 T13723 T13721 arg2Of h,and
R11089 T13723 T13722 arg1Of h,6
R11090 T13726 T13724 arg1Of collection,The
R11091 T13726 T13725 arg1Of collection,final
R11092 T13726 T13727 arg1Of collection,of
R11093 T13726 T13729 arg1Of collection,was
R11094 T13726 T13730 arg2Of collection,performed
R11095 T13728 T13727 arg2Of media,of
R11096 T13730 T13729 arg2Of performed,was
R11097 T13730 T13731 arg1Of performed,after
R11098 T13733 T13731 arg2Of h,after
R11099 T13733 T13732 arg1Of h,24
R11254 T13954 T13952 arg1Of analysis,Western
R11255 T13954 T13953 arg1Of analysis,blot
R11256 T13956 T13955 arg2Of stimulation,Following
R11257 T13959 T13961 arg2Of T-cells,centrifuged
R11258 T13959 T13958 arg1Of T-cells,Jurkat
R11259 T13959 T13960 arg1Of T-cells,were
R11260 T13959 T13970 arg2Of T-cells,lysed
R11261 T13959 T13976 arg1Of T-cells,using
R11262 T13961 T13962 arg1Of centrifuged,at
R11263 T13961 T13969 arg1Of centrifuged,and
R11264 T13965 T13962 arg2Of g,at
R11265 T13965 T13963 arg1Of g,1000
R11266 T13965 T13964 arg1Of g,×
R11267 T13965 T13966 arg1Of g,for
R11268 T13968 T13966 arg2Of min,for
R11269 T13968 T13967 arg1Of min,8
R11270 T13969 T13955 arg1Of and,Following
R11271 T13969 T13957 arg1Of and,","
R11272 T13969 T13960 arg2Of and,were
R11273 T13970 T13969 arg2Of lysed,and
R11274 T13970 T13971 arg1Of lysed,on
R11275 T13970 T13973 arg1Of lysed,for
R11276 T13970 T13976 modOf lysed,using
R11277 T13972 T13971 arg2Of ice,on
R11278 T13975 T13973 arg2Of h,for
R11279 T13975 T13974 arg1Of h,2
R11280 T13976 T13979 arg1Of using,with
R11281 T13976 T13987 arg1Of using,(
R11282 T13978 T13976 arg2Of hydroxide,using
R11283 T13978 T13977 arg1Of hydroxide,sodium
R11284 T13981 T13979 arg2Of addition,with
R11285 T13981 T13980 arg1Of addition,the
R11286 T13981 T13982 arg1Of addition,of
R11287 T13986 T13982 arg2Of cocktail,of
R11288 T13986 T13983 arg1Of cocktail,a
R11289 T13986 T13984 arg1Of cocktail,protease
R11290 T13986 T13985 arg1Of cocktail,inhibitor
R11291 T13988 T13987 arg2Of Roche,(
R11292 T13988 T13989 arg1Of Roche,","
R11293 T13988 T13990 arg1Of Roche,Mannheim
R11294 T13991 T13987 arg3Of ),(
R11295 T13993 T13992 arg1Of cells,The
R11296 T13993 T13994 arg1Of cells,were
R11297 T13993 T13996 arg2Of cells,centrifuged
R11298 T13996 T13994 arg2Of centrifuged,were
R11299 T13996 T13995 arg1Of centrifuged,further
R11300 T13996 T13997 arg1Of centrifuged,at
R11301 T13996 T14006 arg1Of centrifuged,and
R11302 T14000 T13998 arg1Of g,8000
R11303 T14000 T13999 arg1Of g,×
R11304 T14000 T14001 arg1Of g,","
R11305 T14001 T13997 arg2Of ",",at
R11306 T14002 T14001 arg2Of 4°C,","
R11307 T14002 T14003 arg1Of 4°C,for
R11308 T14005 T14003 arg2Of min,for
R11309 T14005 T14004 arg1Of min,10
R11310 T14008 T14007 arg1Of supernatants,the
R11311 T14008 T14009 arg1Of supernatants,were
R11312 T14008 T14010 arg2Of supernatants,transferred
R11313 T14010 T14006 arg2Of transferred,and
R11314 T14010 T14009 arg2Of transferred,were
R11315 T14010 T14011 arg1Of transferred,to
R11316 T14013 T14011 arg2Of tubes,to
R11317 T14013 T14012 arg1Of tubes,new
R11318 T14015 T14014 arg1Of proteins,Cytoplasmic
R11319 T14015 T14016 arg1Of proteins,(
R11320 T14015 T14020 arg1Of proteins,were
R11321 T14015 T14021 arg2Of proteins,separated
R11322 T14018 T14016 arg2Of μg,(
R11323 T14018 T14017 arg1Of μg,~8
R11324 T14019 T14016 arg3Of ),(
R11325 T14021 T14020 arg2Of separated,were
R11326 T14021 T14057 arg1Of separated,(
R11327 T14023 T14021 arg1Of SDS-PAGE,separated
R11328 T14023 T14022 arg2Of SDS-PAGE,by
R11329 T14023 T14024 arg1Of SDS-PAGE,(
R11330 T14023 T14028 arg2Of SDS-PAGE,followed
R11331 T14023 T14043 arg1Of SDS-PAGE,(
R11332 T14023 T14046 arg1Of SDS-PAGE,","
R11333 T14026 T14024 arg2Of %,(
R11334 T14026 T14025 arg1Of %,10
R11335 T14027 T14024 arg3Of ),(
R11336 T14031 T14028 arg1Of blotting,followed
R11337 T14031 T14029 arg2Of blotting,by
R11338 T14031 T14030 arg1Of blotting,western
R11339 T14031 T14032 arg1Of blotting,using
R11340 T14035 T14032 arg2Of phospho-PKC,using
R11341 T14035 T14033 arg1Of phospho-PKC,anti-IκBβ
R11342 T14035 T14034 arg1Of phospho-PKC,","
R11343 T14035 T14036 arg1Of phospho-PKC,(
R11344 T14035 T14039 arg1Of phospho-PKC,(
R11345 T14037 T14036 arg2Of pan,(
R11346 T14038 T14036 arg3Of ),(
R11347 T14041 T14039 arg2Of Thr410,(
R11348 T14041 T14040 arg1Of Thr410,ζ
R11349 T14042 T14039 arg3Of ),(
R11350 T14044 T14043 arg2Of 190D10,(
R11351 T14045 T14043 arg3Of ),(
R11352 T14047 T14048 arg1Of anti-Bcl10,(
R11353 T14047 T14055 arg1Of anti-Bcl10,and
R11354 T14051 T14048 arg2Of Technology,(
R11355 T14051 T14049 arg1Of Technology,Cell
R11356 T14051 T14050 arg1Of Technology,Signalling
R11357 T14051 T14052 arg1Of Technology,","
R11358 T14053 T14052 arg2Of Boston,","
R11359 T14054 T14048 arg3Of ),(
R11360 T14055 T14046 arg2Of and,","
R11361 T14056 T14055 arg2Of beta-actin,and
R11362 T14058 T14057 arg2Of Abcam,(
R11363 T14058 T14059 arg1Of Abcam,","
R11364 T14058 T14060 arg1Of Abcam,Cambridge
R11365 T14061 T14057 arg3Of ),(
R11366 T14062 T14063 arg1Of Detection,was
R11367 T14062 T14064 arg2Of Detection,performed
R11368 T14064 T14063 arg2Of performed,was
R11369 T14064 T14065 arg1Of performed,following
R11370 T14066 T14065 arg2Of incubation,following
R11371 T14066 T14067 arg1Of incubation,with
R11372 T14069 T14068 arg1Of Anti-rabbit,ECL™
R11373 T14070 T14067 arg2Of IgG,with
R11374 T14070 T14069 arg1Of IgG,Anti-rabbit
R11375 T14073 T14072 arg1Of peroxidase,horseradish
R11376 T14073 T14074 arg1Of peroxidase,linked
R11377 T14073 T14084 arg2Of peroxidase,developed
R11378 T14074 T14083 arg1Of linked,and
R11379 T14076 T14074 arg2Of antibodies,linked
R11380 T14076 T14075 arg1Of antibodies,whole
R11381 T14076 T14077 arg1Of antibodies,(
R11382 T14079 T14077 arg2Of Biosciences,(
R11383 T14079 T14078 arg1Of Biosciences,Amersham
R11384 T14079 T14080 arg1Of Biosciences,","
R11385 T14081 T14080 arg2Of Buckinghamshire,","
R11386 T14082 T14077 arg3Of ),(
R11387 T14083 T14063 modOf and,was
R11388 T14083 T14071 arg1Of and,","
R11389 T14084 T14083 arg2Of developed,and
R11390 T14085 T14084 arg3Of using,developed
R11391 T14090 T14085 arg2Of Reagents,using
R11392 T14090 T14086 arg1Of Reagents,ECL™
R11393 T14090 T14087 arg1Of Reagents,Western
R11394 T14090 T14088 arg1Of Reagents,Blotting
R11395 T14090 T14089 arg1Of Reagents,Detection
R11396 T14090 T14091 arg1Of Reagents,(
R11397 T14093 T14091 arg2Of Healthcare,(
R11398 T14093 T14092 arg1Of Healthcare,GE
R11399 T14093 T14094 arg1Of Healthcare,","
R11400 T14095 T14094 arg2Of UK,","
R11401 T14096 T14091 arg3Of ),(
R11575 T14307 T14306 arg1Of extraction,RNA
R11576 T14309 T14308 arg1Of T-cells,Jurkat
R11577 T14309 T14310 arg1Of T-cells,were
R11578 T14309 T14311 arg2Of T-cells,treated
R11579 T14311 T14310 arg2Of treated,were
R11580 T14311 T14312 arg1Of treated,with
R11581 T14311 T14322 arg1Of treated,in
R11582 T14313 T14314 arg1Of NF-κB,","
R11583 T14314 T14316 arg1Of ",",and
R11584 T14315 T14314 arg2Of JNK,","
R11585 T14316 T14312 arg2Of and,with
R11586 T14318 T14316 arg2Of inhibitors,and
R11587 T14318 T14317 arg1Of inhibitors,PKC
R11588 T14318 T14319 arg1Of inhibitors,for
R11589 T14321 T14319 arg2Of h,for
R11590 T14321 T14320 arg1Of h,2
R11591 T14324 T14322 arg2Of plates,in
R11592 T14324 T14323 arg1Of plates,6-well
R11593 T14324 T14325 arg2Of plates,followed
R11594 T14327 T14325 arg1Of stimulation,followed
R11595 T14327 T14326 arg2Of stimulation,by
R11596 T14327 T14328 arg1Of stimulation,with
R11597 T14329 T14330 arg1Of 162,nM
R11598 T14331 T14328 arg2Of PMA,with
R11599 T14331 T14329 arg1Of PMA,162
R11600 T14331 T14332 arg1Of PMA,for
R11601 T14334 T14332 arg2Of h,for
R11602 T14334 T14333 arg1Of h,24
R11603 T14336 T14335 arg2Of sampling,At
R11604 T14338 T14337 arg1Of cells,the
R11605 T14338 T14339 arg1Of cells,were
R11606 T14338 T14340 arg2Of cells,pelleted
R11607 T14340 T14335 arg1Of pelleted,At
R11608 T14340 T14339 arg2Of pelleted,were
R11609 T14340 T14341 modOf pelleted,followed
R11610 T14341 T14345 modOf followed,using
R11611 T14344 T14341 arg1Of extraction,followed
R11612 T14344 T14342 arg2Of extraction,by
R11613 T14344 T14343 arg1Of extraction,RNA
R11614 T14345 T14349 arg1Of using,(
R11615 T14348 T14345 arg2Of TRI-reagent,using
R11616 T14348 T14346 arg1Of TRI-reagent,100
R11617 T14348 T14347 arg1Of TRI-reagent,μl
R11618 T14350 T14349 arg2Of Sigma,(
R11619 T14350 T14351 arg1Of Sigma,","
R11620 T14350 T14352 arg1Of Sigma,USA
R11621 T14353 T14349 arg3Of ),(
R11622 T14354 T14355 arg1Of This,was
R11623 T14354 T14356 arg2Of This,followed
R11624 T14356 T14355 arg2Of followed,was
R11625 T14358 T14356 arg1Of addition,followed
R11626 T14358 T14357 arg2Of addition,by
R11627 T14358 T14359 arg1Of addition,of
R11628 T14362 T14359 arg2Of chloroform/isoamylalcohol,of
R11629 T14362 T14360 arg1Of chloroform/isoamylalcohol,100
R11630 T14362 T14361 arg1Of chloroform/isoamylalcohol,μl
R11631 T14362 T14363 arg1Of chloroform/isoamylalcohol,(
R11632 T14364 T14363 arg2Of 24/1,(
R11633 T14365 T14363 arg3Of ),(
R11634 T14367 T14366 arg1Of solutions,The
R11635 T14367 T14368 arg1Of solutions,were
R11636 T14367 T14369 arg2Of solutions,mixed
R11637 T14369 T14368 arg2Of mixed,were
R11638 T14369 T14370 arg1Of mixed,by
R11639 T14372 T14370 arg2Of followed,by
R11640 T14372 T14371 arg2Of followed,vortexing
R11641 T14372 T14375 arg1Of followed,at
R11642 T14372 T14378 arg1Of followed,for
R11643 T14374 T14372 arg1Of centrifugation,followed
R11644 T14374 T14373 arg2Of centrifugation,by
R11645 T14377 T14375 arg2Of rpm,at
R11646 T14377 T14376 arg1Of rpm,"12,000"
R11647 T14380 T14378 arg2Of min,for
R11648 T14380 T14379 arg1Of min,15
R11649 T14380 T14381 arg1Of min,at
R11650 T14382 T14381 arg2Of 4°C.,at
R11651 T14385 T14383 arg1Of phase,The
R11652 T14385 T14384 arg1Of phase,upper
R11653 T14385 T14386 arg1Of phase,was
R11654 T14385 T14387 arg2Of phase,transferred
R11655 T14385 T14400 arg2Of phase,incubated
R11656 T14387 T14388 arg1Of transferred,to
R11657 T14387 T14392 modOf transferred,followed
R11658 T14387 T14399 arg1Of transferred,and
R11659 T14391 T14388 arg2Of tube,to
R11660 T14391 T14389 arg1Of tube,a
R11661 T14391 T14390 arg1Of tube,new
R11662 T14394 T14392 arg1Of addition,followed
R11663 T14394 T14393 arg2Of addition,by
R11664 T14394 T14395 arg1Of addition,of
R11665 T14398 T14395 arg2Of iso-propanol,of
R11666 T14398 T14396 arg1Of iso-propanol,100
R11667 T14398 T14397 arg1Of iso-propanol,μl
R11668 T14399 T14368 modOf and,were
R11669 T14399 T14386 arg2Of and,was
R11670 T14400 T14399 arg2Of incubated,and
R11671 T14400 T14401 arg1Of incubated,at
R11672 T14400 T14404 arg1Of incubated,for
R11673 T14403 T14401 arg2Of temperature,at
R11674 T14403 T14402 arg1Of temperature,room
R11675 T14406 T14404 arg2Of min,for
R11676 T14406 T14405 arg1Of min,10
R11677 T14407 T14408 arg1Of RNA,was
R11678 T14407 T14410 arg2Of RNA,pelleted
R11679 T14407 T14422 arg2Of RNA,washed
R11680 T14410 T14413 arg1Of pelleted,at
R11681 T14410 T14416 arg1Of pelleted,for
R11682 T14410 T14421 arg1Of pelleted,and
R11683 T14412 T14410 arg1Of centrifugation,pelleted
R11684 T14412 T14411 arg2Of centrifugation,by
R11685 T14415 T14413 arg2Of rpm,at
R11686 T14415 T14414 arg1Of rpm,"12,000"
R11687 T14418 T14416 arg2Of min,for
R11688 T14418 T14417 arg1Of min,15
R11689 T14418 T14419 arg1Of min,at
R11690 T14420 T14419 arg2Of 4°C,at
R11691 T14421 T14408 arg2Of and,was
R11692 T14421 T14409 arg1Of and,then
R11693 T14422 T14421 arg2Of washed,and
R11694 T14422 T14423 arg1Of washed,with
R11695 T14424 T14425 arg1Of 70,%
R11696 T14426 T14423 arg2Of ethanol,with
R11697 T14426 T14424 arg1Of ethanol,70
R11698 T14429 T14427 arg1Of pellet,The
R11699 T14429 T14428 arg1Of pellet,RNA
R11700 T14429 T14430 arg1Of pellet,was
R11701 T14429 T14431 arg2Of pellet,dissolved
R11702 T14431 T14430 arg2Of dissolved,was
R11703 T14431 T14432 arg1Of dissolved,in
R11704 T14431 T14438 arg1Of dissolved,and
R11705 T14437 T14432 arg2Of water,in
R11706 T14437 T14433 arg1Of water,25
R11707 T14437 T14434 arg1Of water,μl
R11708 T14437 T14435 arg1Of water,RNase
R11709 T14437 T14436 arg1Of water,free
R11710 T14440 T14441 arg1Of yield,and
R11711 T14441 T14439 arg1Of and,the
R11712 T14441 T14443 arg1Of and,(
R11713 T14441 T14446 arg1Of and,was
R11714 T14441 T14447 arg2Of and,determined
R11715 T14442 T14441 arg2Of ratio,and
R11716 T14444 T14443 arg2Of A260/A280,(
R11717 T14445 T14443 arg3Of ),(
R11718 T14447 T14438 arg2Of determined,and
R11719 T14447 T14446 arg2Of determined,was
R11720 T14448 T14447 arg3Of using,determined
R11721 T14449 T14448 arg2Of NanoVue,using
R11722 T14449 T14450 arg1Of NanoVue,(
R11723 T14452 T14450 arg2Of Healthcare,(
R11724 T14452 T14451 arg1Of Healthcare,GE
R11725 T14452 T14453 arg1Of Healthcare,","
R11726 T14454 T14453 arg2Of UK,","
R11727 T14455 T14450 arg3Of ),(
R11728 T14457 T14456 arg1Of samples,The
R11729 T14457 T14458 arg1Of samples,were
R11730 T14457 T14459 arg2Of samples,stored
R11731 T14459 T14458 arg2Of stored,were
R11732 T14459 T14460 arg1Of stored,at
R11733 T14459 T14462 arg1Of stored,until
R11734 T14461 T14460 arg2Of -80°C,at
R11735 T14464 T14462 arg2Of use,until
R11736 T14464 T14463 arg1Of use,further
R11930 T14702 T14699 arg1Of PCR,Reverse
R11931 T14702 T14700 arg1Of PCR,transcription
R11932 T14702 T14701 arg1Of PCR,quantitative
R11933 T14702 T14703 arg1Of PCR,(
R11934 T14704 T14703 arg2Of RT-qPCR,(
R11935 T14705 T14703 arg3Of ),(
R11936 T14706 T14707 arg1Of RT-qPCR,was
R11937 T14706 T14708 arg2Of RT-qPCR,used
R11938 T14708 T14707 arg2Of used,was
R11939 T14708 T14718 arg1Of used,in
R11940 T14708 T14722 arg1Of used,following
R11941 T14710 T14708 arg3Of determine,used
R11942 T14710 T14709 arg1Of determine,to
R11943 T14713 T14710 arg2Of levels,determine
R11944 T14713 T14711 arg1Of levels,gene
R11945 T14713 T14712 arg1Of levels,expression
R11946 T14713 T14714 arg1Of levels,of
R11947 T14715 T14716 arg1Of il-6,and
R11948 T14716 T14714 arg2Of and,of
R11949 T14717 T14716 arg2Of cxcl8,and
R11950 T14718 T14720 arg1Of in,to
R11951 T14719 T14718 arg2Of response,in
R11952 T14721 T14718 arg3Of PMA,in
R11953 T14723 T14722 arg2Of inhibition,following
R11954 T14723 T14724 arg1Of inhibition,of
R11955 T14725 T14726 arg1Of NF-κB,","
R11956 T14726 T14728 arg1Of ",",and
R11957 T14727 T14726 arg2Of JNK,","
R11958 T14728 T14724 arg2Of and,of
R11959 T14729 T14728 arg2Of PKC,and
R11960 T14733 T14730 arg1Of sequences,The
R11961 T14733 T14731 arg1Of sequences,following
R11962 T14733 T14732 arg1Of sequences,primer
R11963 T14733 T14734 arg1Of sequences,were
R11964 T14733 T14735 arg2Of sequences,used
R11965 T14735 T14734 arg2Of used,were
R11966 T14735 T14736 arg1Of used,","
R11967 T14737 T14735 arg3Of il-6,used
R11968 T14737 T14738 arg1Of il-6,:
R11969 T14740 T14738 arg2Of TGTGAAAGCAGCAAAGAGGCACTG,:
R11970 T14740 T14739 arg1Of TGTGAAAGCAGCAAAGAGGCACTG,forward-
R11971 T14740 T14741 arg1Of TGTGAAAGCAGCAAAGAGGCACTG,","
R11972 T14740 T14744 arg1Of TGTGAAAGCAGCAAAGAGGCACTG,;
R11973 T14743 T14741 arg2Of ACAGCTCTGGCTTGTTCCTCACTA,","
R11974 T14743 T14742 arg1Of ACAGCTCTGGCTTGTTCCTCACTA,reverse-
R11975 T14745 T14744 arg2Of cxcl8,;
R11976 T14745 T14746 arg1Of cxcl8,:
R11977 T14748 T14746 arg2Of ACCACACTGCGCCAACACAGAAAT,:
R11978 T14748 T14747 arg1Of ACCACACTGCGCCAACACAGAAAT,forward-
R11979 T14748 T14749 arg1Of ACCACACTGCGCCAACACAGAAAT,","
R11980 T14751 T14749 arg2Of AAACTTCTCCACAACCCTCTGCAC,","
R11981 T14751 T14750 arg1Of AAACTTCTCCACAACCCTCTGCAC,reverse-
R11982 T14753 T14752 arg1Of conditions,Thermocycling
R11983 T14753 T14754 arg1Of conditions,for
R11984 T14753 T14762 arg1Of conditions,consisted
R11985 T14756 T14754 arg2Of Green,for
R11986 T14756 T14755 arg1Of Green,CYBR
R11987 T14756 T14757 arg1Of Green,(
R11988 T14758 T14757 arg2Of Quanta,(
R11989 T14758 T14759 arg1Of Quanta,","
R11990 T14758 T14760 arg1Of Quanta,USA
R11991 T14761 T14757 arg3Of ),(
R11992 T14762 T14763 arg1Of consisted,of
R11993 T14762 T14773 modOf consisted,followed
R11994 T14766 T14763 arg2Of step,of
R11995 T14766 T14764 arg1Of step,a
R11996 T14766 T14765 arg1Of step,denaturation
R11997 T14766 T14767 arg1Of step,for
R11998 T14769 T14767 arg2Of min,for
R11999 T14769 T14768 arg1Of min,10
R12000 T14769 T14770 arg1Of min,at
R12001 T14772 T14770 arg2Of °C,at
R12002 T14772 T14771 arg1Of °C,95
R12003 T14776 T14773 arg1Of cycles,followed
R12004 T14776 T14774 arg2Of cycles,by
R12005 T14776 T14775 arg1Of cycles,60
R12006 T14776 T14777 arg1Of cycles,of
R12007 T14778 T14777 arg2Of 95°C,of
R12008 T14778 T14779 arg1Of 95°C,for
R12009 T14780 T14781 arg1Of 1s,and
R12010 T14781 T14779 arg2Of and,for
R12011 T14782 T14781 arg2Of 60°C,and
R12012 T14782 T14783 arg1Of 60°C,for
R12013 T14784 T14783 arg2Of 30s,for
R12014 T14786 T14785 arg1Of expression,Gene
R12015 T14786 T14787 arg1Of expression,was
R12016 T14786 T14788 arg2Of expression,analysed
R12017 T14788 T14787 arg2Of analysed,was
R12018 T14788 T14789 modOf analysed,using
R12019 T14790 T14789 arg2Of Stratagene,using
R12020 T14790 T14791 arg1Of Stratagene,(
R12021 T14790 T14794 arg1Of Stratagene,(
R12022 T14792 T14791 arg2Of Mx3000p™,(
R12023 T14793 T14791 arg3Of ),(
R12024 T14796 T14794 arg2Of diagnostics,(
R12025 T14796 T14795 arg1Of diagnostics,AH
R12026 T14797 T14794 arg3Of ),(
R12027 T14801 T14798 arg1Of values,The
R12028 T14801 T14799 arg2Of values,obtained
R12029 T14801 T14800 arg1Of values,Ct
R12030 T14801 T14802 arg1Of values,were
R12031 T14801 T14803 arg2Of values,normalized
R12032 T14803 T14802 arg2Of normalized,were
R12033 T14803 T14804 arg1Of normalized,against
R12034 T14805 T14804 arg2Of 18S,against
R12035 T14812 T14808 arg1Of values,all
R12036 T14812 T14809 arg2Of values,measured
R12037 T14812 T14810 arg1Of values,18S
R12038 T14812 T14811 arg1Of values,Ct
R12039 T14812 T14813 arg1Of values,were
R12040 T14812 T14814 arg2Of values,used
R12041 T14814 T14806 arg1Of used,Initially
R12042 T14814 T14807 arg1Of used,","
R12043 T14814 T14813 arg2Of used,were
R12044 T14816 T14814 arg3Of calculate,used
R12045 T14816 T14815 arg1Of calculate,to
R12046 T14820 T14816 arg2Of value,calculate
R12047 T14820 T14817 arg1Of value,a
R12048 T14820 T14818 arg1Of value,mean
R12049 T14820 T14819 arg1Of value,Ct
R12050 T14820 T14821 arg1Of value,that
R12051 T14820 T14822 arg1Of value,was
R12052 T14820 T14823 arg2Of value,used
R12053 T14823 T14822 arg2Of used,was
R12054 T14823 T14824 modOf used,to
R12055 T14825 T14824 arg1Of determine,to
R12056 T14828 T14825 arg2Of values,determine
R12057 T14828 T14826 arg1Of values,the
R12058 T14828 T14827 arg1Of values,ΔCt
R12059 T14828 T14829 arg1Of values,for
R12060 T14831 T14829 arg2Of sample,for
R12061 T14831 T14830 arg1Of sample,each
R12062 T14834 T14832 arg1Of patterns,Gene
R12063 T14834 T14833 arg1Of patterns,expression
R12064 T14834 T14835 arg1Of patterns,for
R12065 T14834 T14839 arg1Of patterns,were
R12066 T14834 T14841 arg2Of patterns,normalized
R12067 T14836 T14837 arg1Of il-6,and
R12068 T14837 T14835 arg2Of and,for
R12069 T14838 T14837 arg2Of cxcl8,and
R12070 T14841 T14839 arg2Of normalized,were
R12071 T14841 T14840 arg1Of normalized,then
R12072 T14841 T14842 arg1Of normalized,with
R12073 T14843 T14842 arg2Of regard,with
R12074 T14843 T14844 arg1Of regard,to
R12075 T14848 T14844 arg2Of ΔCt,to
R12076 T14848 T14845 arg1Of ΔCt,the
R12077 T14848 T14846 arg1Of ΔCt,samples
R12078 T14848 T14847 arg1Of ΔCt,18S
R12153 T14994 T14993 arg1Of analysis,Statistical
R12154 T14997 T14995 arg1Of differences,Statistical
R12155 T14997 T14996 arg1Of differences,significant
R12156 T14997 T14998 arg1Of differences,were
R12157 T14997 T14999 arg2Of differences,determined
R12158 T14999 T14998 arg2Of determined,were
R12159 T15000 T14999 arg3Of using,determined
R12160 T15002 T15003 arg2Of Student,'s
R12161 T15004 T15000 arg2Of t-test,using
R12162 T15004 T15001 arg1Of t-test,two-tailed
R12163 T15004 T15003 arg1Of t-test,'s
R12164 T15004 T15005 arg1Of t-test,(
R12165 T15006 T15005 arg2Of *p,(
R12166 T15006 T15007 arg1Of *p,<
R12167 T15006 T15008 arg1Of *p,0.05
R12168 T15006 T15009 arg1Of *p,;
R12169 T15006 T15013 arg1Of *p,;
R12170 T15012 T15009 arg2Of 0.01,;
R12171 T15012 T15010 arg1Of 0.01,**p
R12172 T15012 T15011 arg1Of 0.01,<
R12173 T15014 T15013 arg2Of ***p,;
R12174 T15014 T15015 arg1Of ***p,<
R12175 T15014 T15016 arg1Of ***p,0.001
R12176 T15017 T15005 arg3Of ),(
R12300 T15151 T15150 arg1Of activation,AP-1
R12301 T15151 T15152 arg1Of activation,following
R12302 T15154 T15152 arg2Of exposure,following
R12303 T15154 T15153 arg1Of exposure,long-term
R12304 T15154 T15155 arg1Of exposure,of
R12305 T15154 T15158 arg1Of exposure,to
R12306 T15157 T15155 arg2Of T-cells,of
R12307 T15157 T15156 arg1Of T-cells,Jurkat
R12308 T15159 T15158 arg2Of PMA,to
R12309 T15161 T15160 arg1Of T-cells,Jurkat
R12310 T15161 T15162 arg1Of T-cells,were
R12311 T15161 T15163 arg2Of T-cells,transfected
R12312 T15163 T15162 arg2Of transfected,were
R12313 T15163 T15164 arg1Of transfected,with
R12314 T15167 T15164 arg2Of plasmids,with
R12315 T15167 T15165 arg1Of plasmids,luciferase
R12316 T15167 T15166 arg1Of plasmids,reporter
R12317 T15167 T15168 arg1Of plasmids,containing
R12318 T15167 T15214 arg1Of plasmids,(
R12319 T15168 T15178 arg1Of containing,in
R12320 T15168 T15209 arg1Of containing,in
R12321 T15173 T15172 arg2Of A,(
R12322 T15174 T15172 arg3Of ),(
R12323 T15177 T15168 arg2Of activation,containing
R12324 T15177 T15169 arg1Of activation,the
R12325 T15177 T15170 arg1Of activation,AP-1
R12326 T15177 T15171 arg1Of activation,cis-elements.
R12327 T15177 T15172 arg1Of activation,(
R12328 T15177 T15175 arg1Of activation,Time-dependent
R12329 T15177 T15176 arg1Of activation,AP-1
R12330 T15178 T15208 arg1Of in,and
R12331 T15179 T15178 arg2Of response,in
R12332 T15179 T15180 arg1Of response,to
R12333 T15181 T15180 arg2Of PMA.,to
R12334 T15181 T15182 arg1Of PMA.,(
R12335 T15181 T15185 arg1Of PMA.,HK
R12336 T15181 T15190 arg2Of PMA.,activate
R12337 T15183 T15182 arg2Of B,(
R12338 T15184 T15182 arg3Of ),(
R12339 T15187 T15186 arg1Of coli,E.
R12340 T15187 T15188 arg1Of coli,does
R12341 T15187 T15190 arg1Of coli,activate
R12342 T15190 T15188 arg2Of activate,does
R12343 T15190 T15189 arg1Of activate,not
R12344 T15191 T15178 arg3Of AP-1.,in
R12345 T15191 T15199 modOf AP-1.,were
R12346 T15193 T15192 arg2Of C,(
R12347 T15194 T15192 arg3Of ),(
R12348 T15196 T15192 arg1Of activation,(
R12349 T15196 T15195 arg1Of activation,Dose-dependent
R12350 T15196 T15197 arg1Of activation,of
R12351 T15196 T15199 arg1Of activation,were
R12352 T15196 T15200 arg2Of activation,performed
R12353 T15198 T15197 arg2Of AP-1,of
R12354 T15200 T15199 arg2Of performed,were
R12355 T15201 T15200 arg3Of using,performed
R12356 T15202 T15201 arg2Of PMA,using
R12357 T15202 T15203 arg1Of PMA,alone
R12358 T15202 T15204 arg1Of PMA,(
R12359 T15206 T15204 arg2Of bars,(
R12360 T15206 T15205 arg1Of bars,grey
R12361 T15207 T15204 arg3Of ),(
R12362 T15209 T15208 arg2Of in,and
R12363 T15210 T15209 arg2Of combination,in
R12364 T15210 T15211 arg1Of combination,with
R12365 T15213 T15211 arg2Of ionophore,with
R12366 T15213 T15212 arg1Of ionophore,calcium
R12367 T15217 T15214 arg2Of μM,(
R12368 T15217 T15215 arg1Of μM,CaI
R12369 T15217 T15216 arg1Of μM,955
R12370 T15217 T15218 arg1Of μM,","
R12371 T15220 T15218 arg2Of bars,","
R12372 T15220 T15219 arg1Of bars,black
R12373 T15221 T15214 arg3Of ),(
R12374 T15223 T15222 arg2Of (,.
R12375 T15224 T15222 arg3Of D,.
R12376 T15227 T15222 arg1Of ent c,.
R12377 T15227 T15225 arg1Of ent c,) TCR-
R12378 T15227 T15226 arg1Of ent c,/- defici
R12379 T15227 T15228 arg1Of ent c,ells resp
R12380 T15227 T15236 arg1Of ent c,2 nM) by up-r
R12381 T15228 T15162 modOf ells resp,were
R12382 T15228 T15229 arg1Of ells resp,on
R12383 T15228 T15235 arg1Of ells resp,16
R12384 T15230 T15229 arg2Of ded,on
R12385 T15230 T15231 arg1Of ded,t
R12386 T15233 T15231 arg2Of MA,t
R12387 T15233 T15232 arg1Of MA,o P
R12388 T15234 T15231 arg3Of (,t
R12389 T15236 T15235 arg2Of 2 nM) by up-r,16
R12390 T15238 T15236 arg2Of ating AP,2 nM) by up-r
R12391 T15238 T15237 arg1Of ating AP,egul
R12392 T15240 T15239 arg1Of significance,Statistical
R12393 T15240 T15241 arg1Of significance,from
R12394 T15240 T15244 arg1Of significance,was
R12395 T15240 T15245 arg2Of significance,determined
R12396 T15243 T15241 arg2Of control,from
R12397 T15243 T15242 arg1Of control,the
R12398 T15245 T15244 arg2Of determined,was
R12399 T15246 T15245 arg3Of using,determined
R12400 T15247 T15248 arg2Of Student,'s
R12401 T15249 T15246 arg2Of t-test.,using
R12402 T15249 T15248 arg1Of t-test.,'s
R12403 T15249 T15250 arg1Of t-test.,(
R12404 T15251 T15250 arg2Of n,(
R12405 T15251 T15252 arg1Of n,=
R12406 T15251 T15253 arg1Of n,4
R12407 T15254 T15250 arg3Of ),(
R12408 T15255 T15256 arg1Of Controls,were
R12409 T15255 T15258 arg2Of Controls,set
R12410 T15258 T15256 arg2Of set,were
R12411 T15258 T15257 arg1Of set,arbitrarily
R12412 T15258 T15259 arg1Of set,to
R12413 T15260 T15259 arg2Of 1,to
R12536 T15426 T15425 arg1Of down-regulation,NF-κB
R12537 T15426 T15427 arg1Of down-regulation,by
R12538 T15426 T15431 arg1Of down-regulation,by
R12539 T15426 T15433 arg1Of down-regulation,killed
R12540 T15428 T15429 arg1Of PMA,and
R12541 T15429 T15427 arg2Of and,by
R12542 T15430 T15429 arg2Of up-regulation,and
R12543 T15432 T15431 arg2Of heat,by
R12544 T15433 T15437 arg1Of killed,following
R12545 T15436 T15433 arg2Of MG1655,killed
R12546 T15436 T15434 arg1Of MG1655,E.
R12547 T15436 T15435 arg1Of MG1655,coli
R12548 T15439 T15437 arg2Of stimulation,following
R12549 T15439 T15438 arg1Of stimulation,long-term
R12550 T15440 T15441 arg1Of Transfection,of
R12551 T15440 T15444 arg1Of Transfection,was
R12552 T15440 T15445 arg2Of Transfection,performed
R12553 T15443 T15441 arg2Of T-cells,of
R12554 T15443 T15442 arg1Of T-cells,Jurkat
R12555 T15445 T15444 arg2Of performed,was
R12556 T15446 T15445 arg3Of using,performed
R12557 T15449 T15446 arg2Of plasmids,using
R12558 T15449 T15447 arg1Of plasmids,luciferase
R12559 T15449 T15448 arg1Of plasmids,reporter
R12560 T15449 T15450 arg1Of plasmids,containing
R12561 T15454 T15453 arg2Of A,(
R12562 T15455 T15453 arg3Of ),(
R12563 T15457 T15450 arg2Of stimulation,containing
R12564 T15457 T15451 arg1Of stimulation,NF-κB
R12565 T15457 T15452 arg1Of stimulation,cis-elements.
R12566 T15457 T15453 arg1Of stimulation,(
R12567 T15457 T15456 arg1Of stimulation,Time-dependent
R12568 T15457 T15458 arg1Of stimulation,of
R12569 T15460 T15458 arg2Of T-cells,of
R12570 T15460 T15459 arg1Of T-cells,Jurkat
R12571 T15460 T15461 arg1Of T-cells,using
R12572 T15462 T15461 arg2Of PMA,using
R12573 T15464 T15463 arg1Of activation,NF-κB
R12574 T15464 T15465 arg1Of activation,was
R12575 T15464 T15466 arg2Of activation,evaluated
R12576 T15466 T15465 arg2Of evaluated,was
R12577 T15466 T15467 modOf evaluated,using
R12578 T15470 T15468 arg1Of coli,HK
R12579 T15470 T15469 arg1Of coli,E.
R12580 T15470 T15471 arg1Of coli,in
R12581 T15470 T15477 arg1Of coli,and
R12582 T15474 T15473 arg2Of B,(
R12583 T15475 T15473 arg3Of ),(
R12584 T15476 T15471 arg2Of dose-,in
R12585 T15476 T15472 arg1Of dose-,a
R12586 T15476 T15473 arg1Of dose-,(
R12587 T15477 T15467 arg2Of and,using
R12588 T15479 T15478 arg2Of C,(
R12589 T15480 T15478 arg3Of ),(
R12590 T15482 T15477 arg2Of manner,and
R12591 T15482 T15478 arg1Of manner,(
R12592 T15482 T15481 arg1Of manner,time-dependant
R12593 T15484 T15483 arg1Of ionophore,Calcium
R12594 T15484 T15485 arg1Of ionophore,increased
R12595 T15484 T15495 arg1Of ionophore,resulted
R12596 T15485 T15488 arg1Of increased,following
R12597 T15485 T15494 arg1Of increased,and
R12598 T15487 T15485 arg2Of activity,increased
R12599 T15487 T15486 arg1Of activity,NF-κB
R12600 T15490 T15488 arg2Of exposure,following
R12601 T15490 T15489 arg1Of exposure,PMA
R12602 T15490 T15491 arg1Of exposure,(
R12603 T15492 T15491 arg2Of E,(
R12604 T15493 T15491 arg3Of ),(
R12605 T15495 T15494 arg2Of resulted,and
R12606 T15495 T15496 arg1Of resulted,in
R12607 T15495 T15500 arg1Of resulted,in
R12608 T15499 T15496 arg2Of regulation,in
R12609 T15499 T15497 arg1Of regulation,a
R12610 T15499 T15498 arg1Of regulation,negative
R12611 T15501 T15500 arg2Of response,in
R12612 T15501 T15502 arg1Of response,to
R12613 T15503 T15502 arg2Of HK,to
R12614 T15506 T15500 arg3Of stimulation,in
R12615 T15506 T15504 arg1Of stimulation,E.
R12616 T15506 T15505 arg1Of stimulation,coli
R12617 T15506 T15507 arg1Of stimulation,(
R12618 T15508 T15507 arg2Of D,(
R12619 T15509 T15507 arg3Of ),(
R12620 T15511 T15510 arg1Of significance,Statistical
R12621 T15511 T15512 arg1Of significance,from
R12622 T15511 T15515 arg1Of significance,was
R12623 T15511 T15516 arg2Of significance,determined
R12624 T15514 T15512 arg2Of control,from
R12625 T15514 T15513 arg1Of control,the
R12626 T15516 T15515 arg2Of determined,was
R12627 T15517 T15516 arg3Of using,determined
R12628 T15518 T15519 arg2Of Student,'s
R12629 T15520 T15517 arg2Of t-test.,using
R12630 T15520 T15519 arg1Of t-test.,'s
R12631 T15520 T15521 arg1Of t-test.,(
R12632 T15522 T15521 arg2Of n,(
R12633 T15522 T15523 arg1Of n,=
R12634 T15522 T15524 arg1Of n,4
R12635 T15525 T15521 arg3Of ),(
R12636 T15526 T15527 arg1Of Controls,were
R12637 T15526 T15529 arg2Of Controls,set
R12638 T15529 T15527 arg2Of set,were
R12639 T15529 T15528 arg1Of set,arbitrarily
R12640 T15529 T15530 arg1Of set,to
R12641 T15531 T15530 arg2Of 1,to
R12762 T15704 T15705 arg1Of CXCL8,","
R12763 T15705 T15707 arg1Of ",",and
R12764 T15706 T15705 arg2Of IL-6,","
R12765 T15708 T15707 arg2Of TNF,and
R12766 T15709 T15704 arg1Of expression,CXCL8
R12767 T15709 T15706 arg1Of expression,IL-6
R12768 T15709 T15708 arg1Of expression,TNF
R12769 T15709 T15710 arg1Of expression,following
R12770 T15712 T15710 arg2Of stimulation,following
R12771 T15712 T15711 arg1Of stimulation,long-term
R12772 T15712 T15713 arg1Of stimulation,with
R12773 T15714 T15713 arg2Of PMA,with
R12774 T15716 T15715 arg1Of T-cells,Jurkat
R12775 T15716 T15717 arg1Of T-cells,were
R12776 T15716 T15719 arg2Of T-cells,treated
R12777 T15716 T15727 arg2Of T-cells,stimulated
R12778 T15716 T15735 arg2Of T-cells,incubated
R12779 T15719 T15720 arg1Of treated,with
R12780 T15719 T15726 arg1Of treated,or
R12781 T15721 T15720 arg2Of media,with
R12782 T15721 T15722 arg1Of media,(
R12783 T15724 T15722 arg2Of bars,(
R12784 T15724 T15723 arg1Of bars,white
R12785 T15725 T15722 arg3Of ),(
R12786 T15726 T15734 arg1Of or,and
R12787 T15727 T15726 arg2Of stimulated,or
R12788 T15727 T15728 arg1Of stimulated,with
R12789 T15729 T15728 arg2Of PMA,with
R12790 T15729 T15730 arg1Of PMA,(
R12791 T15732 T15730 arg2Of bars,(
R12792 T15732 T15731 arg1Of bars,black
R12793 T15733 T15730 arg3Of ),(
R12794 T15734 T15717 arg2Of and,were
R12795 T15734 T15718 arg1Of and,either
R12796 T15735 T15734 arg2Of incubated,and
R12797 T15735 T15736 arg1Of incubated,for
R12798 T15738 T15737 arg1Of h,1
R12799 T15738 T15739 arg1Of h,","
R12800 T15739 T15742 arg1Of ",",","
R12801 T15741 T15739 arg2Of h,","
R12802 T15741 T15740 arg1Of h,2
R12803 T15742 T15745 arg1Of ",",and
R12804 T15744 T15742 arg2Of h,","
R12805 T15744 T15743 arg1Of h,6
R12806 T15745 T15736 arg2Of and,for
R12807 T15747 T15745 arg2Of h,and
R12808 T15747 T15746 arg1Of h,24
R12809 T15749 T15748 arg1Of media,Aged
R12810 T15749 T15750 arg1Of media,was
R12811 T15749 T15751 arg2Of media,added
R12812 T15751 T15750 arg2Of added,was
R12813 T15751 T15752 arg1Of added,following
R12814 T15751 T15761 arg1Of added,(
R12815 T15755 T15752 arg2Of step,following
R12816 T15755 T15753 arg1Of step,each
R12817 T15755 T15754 arg1Of step,centrifugation
R12818 T15755 T15756 arg1Of step,representative
R12819 T15756 T15757 arg1Of representative,to
R12820 T15760 T15757 arg2Of time,to
R12821 T15760 T15758 arg1Of time,the
R12822 T15760 T15759 arg1Of time,stimulation
R12823 T15762 T15761 arg2Of see,(
R12824 T15763 T15764 arg1Of Materials,and
R12825 T15764 T15762 arg2Of and,see
R12826 T15765 T15764 arg2Of methods,and
R12827 T15766 T15761 arg3Of ),(
R12828 T15768 T15767 arg1Of levels,Cytokine
R12829 T15768 T15769 arg1Of levels,(
R12830 T15770 T15769 arg2Of A,(
R12831 T15771 T15769 arg3Of ),(
R12832 T15772 T15768 arg1Of CXCL8,levels
R12833 T15772 T15773 arg1Of CXCL8,","
R12834 T15773 T15778 arg1Of ",",and
R12835 T15775 T15774 arg2Of B,(
R12836 T15776 T15774 arg3Of ),(
R12837 T15777 T15773 arg2Of IL-6,","
R12838 T15777 T15774 arg1Of IL-6,(
R12839 T15778 T15783 arg1Of and,were
R12840 T15778 T15784 arg2Of and,detected
R12841 T15780 T15779 arg2Of C,(
R12842 T15781 T15779 arg3Of ),(
R12843 T15782 T15778 arg2Of TNF,and
R12844 T15782 T15779 arg1Of TNF,(
R12845 T15784 T15783 arg2Of detected,were
R12846 T15786 T15784 arg1Of ELISA,detected
R12847 T15786 T15785 arg2Of ELISA,by
R12848 T15788 T15787 arg1Of significance,Statistical
R12849 T15788 T15789 arg1Of significance,from
R12850 T15788 T15792 arg1Of significance,was
R12851 T15788 T15793 arg2Of significance,determined
R12852 T15791 T15789 arg2Of control,from
R12853 T15791 T15790 arg1Of control,the
R12854 T15793 T15792 arg2Of determined,was
R12855 T15794 T15793 arg3Of using,determined
R12856 T15795 T15796 arg2Of Student,'s
R12857 T15797 T15794 arg2Of t-test.,using
R12858 T15797 T15796 arg1Of t-test.,'s
R12859 T15797 T15798 arg1Of t-test.,(
R12860 T15799 T15798 arg2Of n,(
R12861 T15799 T15800 arg1Of n,=
R12862 T15799 T15801 arg1Of n,3
R12863 T15802 T15798 arg3Of ),(
R13004 T15991 T15992 arg1Of Inhibition,of
R13005 T15991 T15995 arg1Of Inhibition,by
R13006 T15994 T15992 arg2Of activity,of
R13007 T15994 T15993 arg1Of activity,NF-κB
R13008 T15996 T15995 arg2Of NAI,by
R13009 T15998 T15997 arg1Of T-cells,Jurkat
R13010 T15998 T15999 arg1Of T-cells,were
R13011 T15998 T16000 arg2Of T-cells,transfected
R13012 T16000 T15999 arg2Of transfected,were
R13013 T16000 T16001 arg1Of transfected,with
R13014 T16004 T16001 arg2Of plasmids,with
R13015 T16004 T16002 arg1Of plasmids,luciferase
R13016 T16004 T16003 arg1Of plasmids,reporter
R13017 T16004 T16005 arg1Of plasmids,containing
R13018 T16007 T16008 arg1Of NF-κB,or
R13019 T16009 T16008 arg2Of AP-1,or
R13020 T16011 T16005 arg2Of elements,containing
R13021 T16011 T16006 arg1Of elements,either
R13022 T16011 T16007 arg1Of elements,NF-κB
R13023 T16011 T16009 arg1Of elements,AP-1
R13024 T16011 T16010 arg1Of elements,cis-acting
R13025 T16013 T16012 arg1Of cells,The
R13026 T16013 T16014 arg1Of cells,were
R13027 T16013 T16015 arg2Of cells,incubated
R13028 T16015 T16014 arg2Of incubated,were
R13029 T16015 T16016 arg1Of incubated,with
R13030 T16015 T16026 modOf incubated,followed
R13031 T16015 T16063 arg1Of incubated,but
R13032 T16019 T16016 arg2Of inhibitor,with
R13033 T16019 T16017 arg1Of inhibitor,NF-κB
R13034 T16019 T16018 arg1Of inhibitor,activation
R13035 T16019 T16020 arg1Of inhibitor,(
R13036 T16019 T16023 arg1Of inhibitor,for
R13037 T16021 T16020 arg2Of NAI,(
R13038 T16022 T16020 arg3Of ),(
R13039 T16025 T16023 arg2Of h,for
R13040 T16025 T16024 arg1Of h,1
R13041 T16028 T16026 arg1Of stimulation,followed
R13042 T16028 T16027 arg2Of stimulation,by
R13043 T16028 T16029 arg1Of stimulation,with
R13044 T16030 T16031 arg1Of PMA,(
R13045 T16030 T16039 arg1Of PMA,or
R13046 T16033 T16032 arg1Of nM,162
R13047 T16033 T16034 arg1Of nM,","
R13048 T16034 T16036 arg1Of ",",and
R13049 T16035 T16034 arg2Of A,","
R13050 T16036 T16031 arg2Of and,(
R13051 T16037 T16036 arg2Of C,and
R13052 T16038 T16031 arg3Of ),(
R13053 T16039 T16029 arg2Of or,with
R13054 T16042 T16040 arg1Of coli,HK
R13055 T16042 T16041 arg1Of coli,E.
R13056 T16042 T16043 arg1Of coli,(
R13057 T16042 T16053 arg1Of coli,for
R13058 T16042 T16056 arg1Of coli,(
R13059 T16047 T16048 arg1Of CFU/ml,","
R13060 T16048 T16050 arg1Of ",",and
R13061 T16049 T16048 arg2Of B,","
R13062 T16050 T16043 arg2Of and,(
R13063 T16050 T16044 arg1Of and,5
R13064 T16050 T16045 arg1Of and,×
R13065 T16050 T16046 arg1Of and,107
R13066 T16051 T16050 arg2Of D,and
R13067 T16052 T16043 arg3Of ),(
R13068 T16055 T16053 arg2Of h.,for
R13069 T16055 T16054 arg1Of h.,24
R13070 T16057 T16056 arg2Of A,(
R13071 T16057 T16058 arg1Of A,","
R13072 T16059 T16058 arg2Of B,","
R13073 T16060 T16056 arg3Of ),(
R13074 T16061 T16039 arg2Of NF-κB,or
R13075 T16061 T16042 arg1Of NF-κB,coli
R13076 T16063 T16062 arg1Of but,","
R13077 T16063 T16064 arg1Of but,not
R13078 T16066 T16065 arg2Of C,(
R13079 T16066 T16067 arg1Of C,","
R13080 T16068 T16067 arg2Of D,","
R13081 T16069 T16065 arg3Of ),(
R13082 T16070 T16065 arg1Of AP-1,(
R13083 T16070 T16071 arg1Of AP-1,was
R13084 T16070 T16072 arg2Of AP-1,inhibited
R13085 T16072 T16063 arg2Of inhibited,but
R13086 T16072 T16071 arg2Of inhibited,was
R13087 T16074 T16073 arg1Of significance,Statistical
R13088 T16074 T16075 arg1Of significance,from
R13089 T16074 T16084 arg1Of significance,was
R13090 T16074 T16085 arg2Of significance,determined
R13091 T16078 T16075 arg2Of control,from
R13092 T16078 T16076 arg1Of control,the
R13093 T16078 T16077 arg1Of control,positive
R13094 T16078 T16079 arg1Of control,(
R13095 T16082 T16079 arg2Of coli,(
R13096 T16082 T16080 arg1Of coli,PMA/HK
R13097 T16082 T16081 arg1Of coli,E.
R13098 T16083 T16079 arg3Of ),(
R13099 T16085 T16084 arg2Of determined,was
R13100 T16086 T16085 arg3Of using,determined
R13101 T16087 T16088 arg2Of Student,'s
R13102 T16089 T16086 arg2Of t-test.,using
R13103 T16089 T16088 arg1Of t-test.,'s
R13104 T16089 T16090 arg1Of t-test.,(
R13105 T16091 T16090 arg2Of n,(
R13106 T16091 T16092 arg1Of n,=
R13107 T16091 T16093 arg1Of n,4
R13108 T16094 T16090 arg3Of ),(
R13109 T16095 T16096 arg1Of Controls,were
R13110 T16095 T16097 arg2Of Controls,set
R13111 T16097 T16096 arg2Of set,were
R13112 T16097 T16098 arg1Of set,to
R13113 T16099 T16098 arg2Of 1,to
R13464 T16538 T16539 arg1Of Involvement,of
R13465 T16538 T16543 arg1Of Involvement,in
R13466 T16540 T16541 arg1Of PKC,and
R13467 T16541 T16539 arg2Of and,of
R13468 T16542 T16541 arg2Of JNK,and
R13469 T16545 T16543 arg2Of expression,in
R13470 T16545 T16544 arg1Of expression,cytokine
R13471 T16547 T16546 arg1Of T-cells,Jurkat
R13472 T16547 T16548 arg1Of T-cells,were
R13473 T16547 T16549 arg2Of T-cells,incubated
R13474 T16549 T16548 arg2Of incubated,were
R13475 T16549 T16550 arg1Of incubated,with
R13476 T16549 T16558 modOf incubated,followed
R13477 T16551 T16552 arg1Of PKC-,and
R13478 T16553 T16552 arg2Of JNK,and
R13479 T16554 T16550 arg2Of inhibitors,with
R13480 T16554 T16551 arg1Of inhibitors,PKC-
R13481 T16554 T16553 arg1Of inhibitors,JNK
R13482 T16554 T16555 arg1Of inhibitors,for
R13483 T16557 T16555 arg2Of h,for
R13484 T16557 T16556 arg1Of h,1
R13485 T16558 T16567 arg1Of followed,for
R13486 T16560 T16558 arg1Of stimulation,followed
R13487 T16560 T16559 arg2Of stimulation,by
R13488 T16560 T16561 arg1Of stimulation,with
R13489 T16562 T16561 arg2Of PMA,with
R13490 T16562 T16563 arg1Of PMA,(
R13491 T16565 T16563 arg2Of nM,(
R13492 T16565 T16564 arg1Of nM,162
R13493 T16566 T16563 arg3Of ),(
R13494 T16569 T16567 arg2Of h.,for
R13495 T16569 T16568 arg1Of h.,24
R13496 T16569 T16570 arg1Of h.,(
R13497 T16571 T16570 arg2Of A,(
R13498 T16572 T16570 arg3Of ),(
R13499 T16574 T16573 arg1Of expression,CXCL8
R13500 T16574 T16575 arg1Of expression,was
R13501 T16574 T16576 arg2Of expression,inhibited
R13502 T16576 T16575 arg2Of inhibited,was
R13503 T16576 T16577 arg1Of inhibited,in
R13504 T16580 T16577 arg2Of manner,in
R13505 T16580 T16578 arg1Of manner,a
R13506 T16580 T16579 arg1Of manner,dose-dependent
R13507 T16583 T16576 arg1Of inhibitors.,inhibited
R13508 T16583 T16581 arg2Of inhibitors.,by
R13509 T16583 T16582 arg1Of inhibitors.,both
R13510 T16583 T16584 arg1Of inhibitors.,(
R13511 T16585 T16584 arg2Of B,(
R13512 T16586 T16584 arg3Of ),(
R13513 T16587 T16588 arg1Of JNK-I,revealed
R13514 T16588 T16548 modOf revealed,were
R13515 T16588 T16575 modOf revealed,was
R13516 T16592 T16588 arg2Of effect,revealed
R13517 T16592 T16589 arg1Of effect,a
R13518 T16592 T16590 arg1Of effect,stronger
R13519 T16592 T16591 arg1Of effect,inhibitory
R13520 T16592 T16593 arg1Of effect,on
R13521 T16592 T16596 arg1Of effect,than
R13522 T16595 T16593 arg2Of expression,on
R13523 T16595 T16594 arg1Of expression,IL-6
R13524 T16600 T16599 arg2Of C,(
R13525 T16601 T16599 arg3Of ),(
R13526 T16603 T16597 arg1Of expression,the
R13527 T16603 T16598 arg1Of expression,PKC-I.
R13528 T16603 T16599 arg1Of expression,(
R13529 T16603 T16602 arg1Of expression,TNF
R13530 T16603 T16604 arg1Of expression,was
R13531 T16603 T16606 arg2Of expression,affected
R13532 T16606 T16596 arg2Of affected,than
R13533 T16606 T16604 arg2Of affected,was
R13534 T16606 T16605 arg1Of affected,not
R13535 T16609 T16606 arg1Of inhibitor,affected
R13536 T16609 T16607 arg2Of inhibitor,by
R13537 T16609 T16608 arg1Of inhibitor,either
R13538 T16611 T16610 arg1Of significance,Statistical
R13539 T16611 T16612 arg1Of significance,from
R13540 T16611 T16619 arg1Of significance,was
R13541 T16611 T16620 arg2Of significance,determined
R13542 T16615 T16612 arg2Of control,from
R13543 T16615 T16613 arg1Of control,the
R13544 T16615 T16614 arg1Of control,positive
R13545 T16615 T16616 arg1Of control,(
R13546 T16617 T16616 arg2Of PMA,(
R13547 T16618 T16616 arg3Of ),(
R13548 T16620 T16619 arg2Of determined,was
R13549 T16621 T16620 arg3Of using,determined
R13550 T16622 T16623 arg2Of Student,'s
R13551 T16624 T16621 arg2Of t-test.,using
R13552 T16624 T16623 arg1Of t-test.,'s
R13553 T16624 T16625 arg1Of t-test.,(
R13554 T16626 T16625 arg2Of n,(
R13555 T16626 T16627 arg1Of n,=
R13556 T16626 T16628 arg1Of n,3
R13557 T16629 T16625 arg3Of ),(
R13714 T16840 T16839 arg1Of inhibition,NF-κB
R13715 T16840 T16841 arg1Of inhibition,by
R13716 T16840 T16843 arg1Of inhibition,correlated
R13717 T16842 T16841 arg2Of PMA,by
R13718 T16843 T16844 arg1Of correlated,to
R13719 T16847 T16844 arg2Of degradation,to
R13720 T16847 T16845 arg1Of degradation,PKC-dependent
R13721 T16847 T16846 arg1Of degradation,Bcl10
R13722 T16848 T16849 arg1Of Levels,of
R13723 T16848 T16852 arg1Of Levels,were
R13724 T16848 T16853 arg2Of Levels,assessed
R13725 T16851 T16849 arg2Of protein,of
R13726 T16851 T16850 arg1Of protein,intracellular
R13727 T16853 T16852 arg2Of assessed,were
R13728 T16853 T16854 arg1Of assessed,following
R13729 T16853 T16878 arg2Of assessed,KC increa
R13730 T16857 T16855 arg1Of stimulation,24
R13731 T16857 T16856 arg1Of stimulation,h
R13732 T16857 T16858 arg1Of stimulation,with
R13733 T16857 T16864 arg1Of stimulation,or
R13734 T16859 T16858 arg2Of PMA,with
R13735 T16859 T16860 arg1Of PMA,(
R13736 T16862 T16860 arg2Of nM,(
R13737 T16862 T16861 arg1Of nM,162
R13738 T16863 T16860 arg3Of ),(
R13739 T16864 T16854 arg2Of or,following
R13740 T16864 T16874 arg1Of or,.
R13741 T16867 T16864 arg2Of coli,or
R13742 T16867 T16865 arg1Of coli,HK
R13743 T16867 T16866 arg1Of coli,E.
R13744 T16867 T16868 arg1Of coli,(
R13745 T16870 T16868 arg2Of ×,(
R13746 T16870 T16869 arg1Of ×,5
R13747 T16870 T16871 arg1Of ×,107
R13748 T16870 T16872 arg1Of ×,CFU/ml
R13749 T16873 T16868 arg3Of ),(
R13750 T16875 T16874 arg2Of (,.
R13751 T16876 T16874 arg3Of A,.
R13752 T16877 T16878 arg1Of ) Phospho-P,KC increa
R13753 T16878 T16879 arg1Of KC increa,se
R13754 T16878 T16893 arg1Of KC increa,IκB decre
R13755 T16878 T16899 modOf KC increa,ion with H
R13756 T16880 T16879 arg2Of d in res,se
R13757 T16880 T16881 arg1Of d in res,po
R13758 T16882 T16883 arg1Of nse,to
R13759 T16883 T16881 arg2Of to ,po
R13760 T16884 T16883 arg2Of PM,to
R13761 T16887 T16879 arg3Of HK E. coli s,se
R13762 T16887 T16885 arg1Of HK E. coli s,A
R13763 T16887 T16886 arg1Of HK E. coli s,and
R13764 T16887 T16888 arg1Of HK E. coli s,t
R13765 T16887 T16892 arg2Of HK E. coli s,tion. (B)
R13766 T16889 T16888 arg2Of i,t
R13767 T16890 T16888 arg3Of m,t
R13768 T16891 T16892 arg1Of ula,tion. (B)
R13769 T16894 T16893 arg2Of ased follow,IκB decre
R13770 T16894 T16895 arg1Of ased follow,ing
R13771 T16896 T16895 arg2Of st,ing
R13772 T16896 T16898 arg1Of st,ulat
R13773 T16898 T16897 arg1Of ulat,im
R13774 T16903 T16902 arg2Of i,t
R13775 T16904 T16902 arg3Of n,t
R13776 T16906 T16900 arg1Of κB activat,K E.
R13777 T16906 T16901 arg1Of κB activat,coli indica
R13778 T16906 T16902 arg1Of κB activat,t
R13779 T16906 T16905 arg1Of κB activat,g NF-
R13780 T16906 T16907 arg1Of κB activat,ion
R13781 T16906 T16908 arg2Of κB activat,. (C) Bcl
R13782 T16908 T16899 arg2Of . (C) Bcl,ion with H
R13783 T16908 T16907 arg2Of . (C) Bcl,ion
R13784 T16908 T16909 arg1Of . (C) Bcl,10 activa
R13785 T16911 T16909 arg2Of inhibited f,10 activa
R13786 T16911 T16910 arg1Of inhibited f,tion was
R13787 T16911 T16912 arg1Of inhibited f,ollo
R13788 T16911 T16914 arg1Of inhibited f,g
R13789 T16911 T16915 arg1Of inhibited f,long-
R13790 T16911 T16916 arg1Of inhibited f,term sti
R13791 T16913 T16912 arg2Of win,ollo
R13792 T16919 T16917 arg1Of "PMA, w",mul
R13793 T16919 T16918 arg1Of "PMA, w",ation with
R13794 T16919 T16920 arg1Of "PMA, w",hi
R13795 T16919 T16922 arg1Of "PMA, w",ex
R13796 T16919 T16926 arg1Of "PMA, w",ffe
R13797 T16919 T16927 arg2Of "PMA, w",ct o
R13798 T16921 T16920 arg2Of ch ,hi
R13799 T16925 T16922 arg2Of itory e,ex
R13800 T16925 T16923 arg1Of itory e,plain
R13801 T16925 T16924 arg1Of itory e,s the inhib
R13802 T16927 T16916 arg2Of ct o,term sti
R13803 T16927 T16926 arg2Of ct o,ffe
R13804 T16927 T16928 arg1Of ct o,f
R13805 T16927 T16932 arg1Of ct o,i
R13806 T16931 T16928 arg2Of F-κB act,f
R13807 T16931 T16929 arg1Of F-κB act,P
R13808 T16931 T16930 arg1Of F-κB act,MA on N
R13809 T16933 T16932 arg2Of v,i
R13810 T16933 T16934 arg1Of v,a
R13811 T16933 T16935 arg1Of v,t
R13812 T16936 T16932 arg3Of i,i
R13859 T17026 T17025 arg1Of T-cells,Jurkat
R13860 T17026 T17027 arg1Of T-cells,were
R13861 T17026 T17028 arg2Of T-cells,stimulated
R13862 T17028 T17027 arg2Of stimulated,were
R13863 T17028 T17029 arg1Of stimulated,with
R13864 T17028 T17041 arg1Of stimulated,for
R13865 T17030 T17031 arg1Of 162,nM
R13866 T17032 T17030 arg1Of PMA,162
R13867 T17032 T17033 arg1Of PMA,and
R13868 T17033 T17029 arg2Of and,with
R13869 T17040 T17033 arg2Of coli,and
R13870 T17040 T17034 arg1Of coli,5
R13871 T17040 T17035 arg1Of coli,×
R13872 T17040 T17036 arg1Of coli,107
R13873 T17040 T17037 arg1Of coli,CFU/ml
R13874 T17040 T17038 arg1Of coli,HK
R13875 T17040 T17039 arg1Of coli,E.
R13876 T17043 T17041 arg2Of h,for
R13877 T17043 T17042 arg1Of h,24
R13906 T17076 T17075 arg1Of T-cells,Jurkat
R13907 T17076 T17077 arg1Of T-cells,were
R13908 T17076 T17078 arg2Of T-cells,treated
R13909 T17078 T17077 arg2Of treated,were
R13910 T17078 T17079 arg1Of treated,with
R13911 T17078 T17093 modOf treated,followed
R13912 T17080 T17081 arg1Of 10,nM
R13913 T17082 T17080 arg1Of NAI,10
R13914 T17082 T17083 arg1Of NAI,","
R13915 T17083 T17079 arg2Of ",",with
R13916 T17083 T17090 arg1Of ",",for
R13917 T17089 T17083 arg2Of PKC-I,","
R13918 T17089 T17084 arg1Of PKC-I,10
R13919 T17089 T17085 arg1Of PKC-I,μM
R13920 T17089 T17086 arg1Of PKC-I,JNK-I
R13921 T17089 T17087 arg1Of PKC-I,or10
R13922 T17089 T17088 arg1Of PKC-I,nM
R13923 T17092 T17090 arg2Of h,for
R13924 T17092 T17091 arg1Of h,2
R13925 T17095 T17093 arg1Of induction,followed
R13926 T17095 T17094 arg2Of induction,by
R13927 T17095 T17096 arg1Of induction,with
R13928 T17097 T17098 arg1Of 162,nM
R13929 T17099 T17096 arg2Of PMA,with
R13930 T17099 T17097 arg1Of PMA,162
R13931 T17099 T17100 arg1Of PMA,for
R13932 T17102 T17100 arg2Of h,for
R13933 T17102 T17101 arg1Of h,24
R1634 T2024 T2025 arg1Of Cytokines,and
R1635 T2025 T2027 arg1Of and,are
R1636 T2025 T2028 arg1Of and,important
R1637 T2026 T2025 arg2Of chemokines,and
R1638 T2027 T2039 arg1Of are,[
R1639 T2028 T2027 arg2Of important,are
R1640 T2028 T2029 arg1Of important,in
R1641 T2028 T2034 arg1Of important,in
R1642 T2029 T2033 arg1Of in,and
R1643 T2032 T2029 arg2Of recruitment,in
R1644 T2032 T2030 arg1Of recruitment,immune
R1645 T2032 T2031 arg1Of recruitment,cell
R1646 T2034 T2033 arg2Of in,and
R1647 T2035 T2034 arg2Of regulation,in
R1648 T2035 T2036 arg1Of regulation,of
R1649 T2038 T2036 arg2Of responses,of
R1650 T2038 T2037 arg1Of responses,inflammatory
R1651 T2040 T2039 arg2Of 1,[
R1652 T2041 T2039 arg3Of ],[
R1653 T2042 T2043 arg1Of T-cells,produce
R1654 T2046 T2043 arg2Of range,produce
R1655 T2046 T2044 arg1Of range,a
R1656 T2046 T2045 arg1Of range,broad
R1657 T2046 T2047 arg1Of range,of
R1658 T2049 T2047 arg2Of mediators,of
R1659 T2049 T2048 arg1Of mediators,inflammatory
R1660 T2049 T2050 arg1Of mediators,","
R1661 T2049 T2051 arg1Of mediators,including
R1662 T2052 T2053 arg1Of IL-2,","
R1663 T2053 T2055 arg1Of ",",","
R1664 T2054 T2053 arg2Of IL-6,","
R1665 T2055 T2057 arg1Of ",",and
R1666 T2056 T2055 arg2Of TNF,","
R1667 T2057 T2051 arg2Of and,including
R1668 T2057 T2059 arg1Of and,","
R1669 T2057 T2061 arg2Of and,of
R1670 T2057 T2062 arg1Of and,which
R1671 T2058 T2057 arg2Of CXCL8,and
R1672 T2060 T2061 arg1Of all,of
R1673 T2060 T2063 arg1Of all,are
R1674 T2060 T2064 arg1Of all,important
R1675 T2063 T2077 arg1Of are,[
R1676 T2064 T2063 arg2Of important,are
R1677 T2064 T2065 arg1Of important,in
R1678 T2067 T2066 arg1Of proliferation,cell
R1679 T2067 T2068 arg1Of proliferation,","
R1680 T2068 T2070 arg1Of ",",","
R1681 T2069 T2068 arg2Of differentiation,","
R1682 T2070 T2072 arg1Of ",",and
R1683 T2071 T2070 arg2Of communication,","
R1684 T2072 T2065 arg2Of and,in
R1685 T2073 T2072 arg2Of initiation,and
R1686 T2073 T2074 arg1Of initiation,of
R1687 T2076 T2074 arg2Of responses,of
R1688 T2076 T2075 arg1Of responses,inflammatory
R1689 T2078 T2077 arg2Of 2,[
R1690 T2079 T2077 arg3Of ],[
R1691 T2081 T2080 arg1Of levels,Elevated
R1692 T2081 T2082 arg1Of levels,of
R1693 T2081 T2087 arg1Of levels,","
R1694 T2081 T2089 arg1Of levels,as
R1695 T2081 T2096 arg1Of levels,are
R1696 T2081 T2097 arg2Of levels,associated
R1697 T2084 T2083 arg1Of cytokines,pro-inflammatory
R1698 T2084 T2085 arg1Of cytokines,and
R1699 T2085 T2082 arg2Of and,of
R1700 T2086 T2085 arg2Of chemokines,and
R1701 T2089 T2088 arg1Of as,such
R1702 T2090 T2091 arg1Of TNF,","
R1703 T2091 T2093 arg1Of ",",and
R1704 T2092 T2091 arg2Of IL-6,","
R1705 T2093 T2089 arg2Of and,as
R1706 T2094 T2093 arg2Of CXCL8,and
R1707 T2097 T2095 arg1Of associated,","
R1708 T2097 T2096 arg2Of associated,are
R1709 T2097 T2098 arg1Of associated,with
R1710 T2101 T2098 arg2Of diseases,with
R1711 T2101 T2099 arg1Of diseases,several
R1712 T2101 T2100 arg1Of diseases,human
R1713 T2101 T2102 arg1Of diseases,including
R1714 T2104 T2103 arg1Of fibrosis,cystic
R1715 T2104 T2105 arg1Of fibrosis,[
R1716 T2104 T2108 arg1Of fibrosis,","
R1717 T2106 T2105 arg2Of 3-5,[
R1718 T2107 T2105 arg3Of ],[
R1719 T2108 T2114 arg1Of ",",and
R1720 T2110 T2108 arg2Of fibrosis,","
R1721 T2110 T2109 arg1Of fibrosis,pulmonary
R1722 T2110 T2111 arg1Of fibrosis,[
R1723 T2112 T2111 arg2Of "6,7",[
R1724 T2113 T2111 arg3Of ],[
R1725 T2114 T2102 arg2Of and,including
R1726 T2115 T2114 arg2Of AIDS,and
R1727 T2115 T2116 arg1Of AIDS,[
R1728 T2117 T2116 arg2Of "8,9",[
R1729 T2118 T2116 arg3Of ],[
R1730 T2119 T2120 arg1Of Induction,of
R1731 T2119 T2122 arg1Of Induction,has
R1732 T2119 T2123 arg1Of Induction,been
R1733 T2119 T2124 arg2Of Induction,suggested
R1734 T2119 T2126 arg1Of Induction,be
R1735 T2119 T2127 arg2Of Induction,mediated
R1736 T2121 T2120 arg2Of CXCL8,of
R1737 T2124 T2122 arg2Of suggested,has
R1738 T2124 T2123 arg2Of suggested,been
R1739 T2124 T2137 arg1Of suggested,","
R1740 T2127 T2124 arg3Of mediated,suggested
R1741 T2127 T2125 arg1Of mediated,to
R1742 T2127 T2126 arg2Of mediated,be
R1743 T2127 T2128 arg1Of mediated,through
R1744 T2127 T2130 arg1Of mediated,in
R1745 T2129 T2128 arg2Of NF-κB,through
R1746 T2131 T2130 arg2Of cooperation,in
R1747 T2131 T2132 arg1Of cooperation,with
R1748 T2133 T2132 arg2Of AP-1,with
R1749 T2133 T2134 arg1Of AP-1,[
R1750 T2135 T2134 arg2Of "10,11",[
R1751 T2136 T2134 arg3Of ],[
R1752 T2137 T2147 arg1Of ",",and
R1753 T2141 T2139 arg1Of mechanism,the
R1754 T2141 T2140 arg1Of mechanism,precise
R1755 T2141 T2142 arg1Of mechanism,is
R1756 T2141 T2145 arg2Of mechanism,elucidated
R1757 T2145 T2137 arg2Of elucidated,","
R1758 T2145 T2138 arg1Of elucidated,however
R1759 T2145 T2142 arg2Of elucidated,is
R1760 T2145 T2143 arg1Of elucidated,not
R1761 T2145 T2144 arg1Of elucidated,fully
R1762 T2147 T2146 arg1Of and,","
R1763 T2149 T2148 arg1Of strategies,treatment
R1764 T2149 T2150 arg2Of strategies,aimed
R1765 T2149 T2154 arg1Of strategies,have
R1766 T2149 T2155 arg1Of strategies,failed
R1767 T2150 T2151 arg1Of aimed,at
R1768 T2152 T2151 arg2Of inhibiting,at
R1769 T2153 T2152 arg2Of CXCL8,inhibiting
R1770 T2155 T2147 arg2Of failed,and
R1771 T2155 T2154 arg2Of failed,have
R1772 T2155 T2156 arg1Of failed,[
R1773 T2157 T2156 arg2Of 12,[
R1774 T2158 T2156 arg3Of ],[
R1775 T2160 T2159 arg1Of production,Persistent
R1776 T2160 T2161 arg1Of production,of
R1777 T2160 T2165 arg1Of production,leads
R1778 T2162 T2163 arg1Of IL-6,and
R1779 T2163 T2161 arg2Of and,of
R1780 T2164 T2163 arg2Of CXCL8,and
R1781 T2165 T2166 arg1Of leads,to
R1782 T2168 T2167 arg1Of inflammation,chronic
R1783 T2168 T2169 arg1Of inflammation,and
R1784 T2169 T2166 arg2Of and,to
R1785 T2171 T2169 arg2Of survival,and
R1786 T2171 T2170 arg2Of survival,enhanced
R1787 T2171 T2172 arg1Of survival,of
R1788 T2173 T2172 arg2Of lymphocytes,of
R1789 T2173 T2174 arg1Of lymphocytes,increasing
R1790 T2177 T2174 arg2Of levels,increasing
R1791 T2177 T2175 arg1Of levels,serum
R1792 T2177 T2176 arg1Of levels,cytokine/chemokine
R1793 T2178 T2179 arg1Of This,forms
R1794 T2181 T2179 arg2Of basis,forms
R1795 T2181 T2180 arg1Of basis,the
R1796 T2181 T2182 arg1Of basis,of
R1797 T2185 T2182 arg2Of disorders,of
R1798 T2185 T2183 arg1Of disorders,several
R1799 T2185 T2184 arg1Of disorders,autoimmune
R1800 T2185 T2186 arg1Of disorders,including
R1801 T2187 T2188 arg1Of plasmacytosis,and
R1802 T2188 T2186 arg2Of and,including
R1803 T2188 T2190 arg1Of and,[
R1804 T2189 T2188 arg2Of hyperplasia,and
R1805 T2191 T2190 arg2Of 13,[
R1806 T2192 T2190 arg3Of ],[
R1807 T2194 T2193 arg1Of develop,To
R1808 T2199 T2194 arg2Of strategies,develop
R1809 T2199 T2195 arg1Of strategies,viable
R1810 T2199 T2196 arg1Of strategies,CXCL8
R1811 T2199 T2197 arg2Of strategies,based
R1812 T2199 T2198 arg1Of strategies,treatment
R1813 T2202 T2193 modOf is,To
R1814 T2202 T2200 arg1Of is,","
R1815 T2203 T2202 arg2Of necessary,is
R1816 T2205 T2211 arg1Of identify,and
R1817 T2208 T2205 arg2Of pathways,identify
R1818 T2208 T2206 arg1Of pathways,the
R1819 T2208 T2207 arg1Of pathways,signalling
R1820 T2208 T2209 arg1Of pathways,regulating
R1821 T2210 T2209 arg2Of CXCL8,regulating
R1822 T2211 T2194 arg1Of and,develop
R1823 T2211 T2201 arg1Of and,it
R1824 T2211 T2202 arg1Of and,is
R1825 T2211 T2203 arg1Of and,necessary
R1826 T2211 T2204 arg1Of and,to
R1827 T2212 T2211 arg2Of determine,and
R1828 T2213 T2212 arg2Of how,determine
R1829 T2214 T2215 arg1Of this,is
R1830 T2214 T2216 arg2Of this,coupled
R1831 T2216 T2213 arg1Of coupled,how
R1832 T2216 T2215 arg2Of coupled,is
R1833 T2216 T2217 arg1Of coupled,to
R1834 T2218 T2219 arg1Of NF-κB,","
R1835 T2219 T2221 arg1Of ",",and
R1836 T2220 T2219 arg2Of AP-1,","
R1837 T2221 T2217 arg2Of and,to
R1838 T2222 T2221 arg2Of IL-6,and
R1839 T2225 T2223 arg1Of pathways,The
R1840 T2225 T2224 arg1Of pathways,signalling
R1841 T2225 T2226 arg1Of pathways,leading
R1842 T2225 T2232 arg1Of pathways,are
R1843 T2225 T2233 arg1Of pathways,overlapping
R1844 T2226 T2227 arg1Of leading,to
R1845 T2228 T2229 arg1Of NF-κB,and
R1846 T2230 T2229 arg2Of AP-1,and
R1847 T2231 T2227 arg2Of activation,to
R1848 T2231 T2228 arg1Of activation,NF-κB
R1849 T2231 T2230 arg1Of activation,AP-1
R1850 T2233 T2232 arg2Of overlapping,are
R1851 T2233 T2234 arg1Of overlapping,","
R1852 T2233 T2235 arg1Of overlapping,where
R1853 T2236 T2237 arg1Of both,are
R1854 T2236 T2238 arg2Of both,involved
R1855 T2238 T2235 arg2Of involved,where
R1856 T2238 T2237 arg2Of involved,are
R1857 T2238 T2239 arg1Of involved,in
R1858 T2241 T2242 arg1Of induction,and
R1859 T2242 T2239 arg2Of and,in
R1860 T2242 T2240 arg1Of and,the
R1861 T2242 T2244 arg1Of and,of
R1862 T2243 T2242 arg2Of regulation,and
R1863 T2245 T2244 arg2Of cytokines/chemokines,of
R1864 T2246 T2247 arg1Of NF-κB,is
R1865 T2246 T2248 arg2Of NF-κB,activated
R1866 T2246 T2271 arg1Of NF-κB,is
R1867 T2246 T2272 arg1Of NF-κB,essential
R1868 T2248 T2247 arg2Of activated,is
R1869 T2248 T2249 arg1Of activated,in
R1870 T2248 T2270 arg1Of activated,and
R1871 T2249 T2251 arg1Of in,to
R1872 T2250 T2249 arg2Of response,in
R1873 T2252 T2249 arg3Of stress,in
R1874 T2252 T2253 arg1Of stress,","
R1875 T2252 T2255 arg1Of stress,as
R1876 T2255 T2254 arg1Of as,such
R1877 T2257 T2256 arg1Of stress,oxidative
R1878 T2257 T2258 arg1Of stress,","
R1879 T2258 T2261 arg1Of ",",","
R1880 T2260 T2258 arg2Of toxins,","
R1881 T2260 T2259 arg1Of toxins,bacterial
R1882 T2261 T2263 arg1Of ",",and
R1883 T2262 T2261 arg2Of viruses,","
R1884 T2263 T2255 arg2Of and,as
R1885 T2265 T2263 arg2Of light,and
R1886 T2265 T2264 arg1Of light,UV
R1887 T2265 T2266 arg1Of light,[
R1888 T2267 T2266 arg2Of 14,[
R1889 T2268 T2266 arg3Of ],[
R1890 T2270 T2269 arg1Of and,","
R1891 T2271 T2270 arg2Of is,and
R1892 T2272 T2271 arg2Of essential,is
R1893 T2272 T2273 arg1Of essential,for
R1894 T2274 T2275 arg1Of differentiation,","
R1895 T2275 T2277 arg1Of ",",and
R1896 T2276 T2275 arg2Of proliferation,","
R1897 T2277 T2273 arg2Of and,for
R1898 T2277 T2279 arg1Of and,of
R1899 T2278 T2277 arg2Of survival,and
R1900 T2282 T2279 arg2Of types,of
R1901 T2282 T2280 arg1Of types,many
R1902 T2282 T2281 arg1Of types,cell
R1903 T2282 T2283 arg1Of types,including
R1904 T2284 T2283 arg2Of T-lymphocytes,including
R1905 T2284 T2285 arg1Of T-lymphocytes,[
R1906 T2286 T2285 arg2Of 15,[
R1907 T2287 T2285 arg3Of ],[
R1908 T2289 T2288 arg1Of activation,AP-1
R1909 T2289 T2290 arg1Of activation,requires
R1910 T2289 T2324 arg1Of activation,regulates
R1911 T2290 T2312 arg1Of requires,through
R1912 T2290 T2323 arg1Of requires,and
R1913 T2291 T2292 arg1Of Fos,(
R1914 T2291 T2301 arg1Of Fos,and
R1915 T2293 T2294 arg1Of c-Fos,","
R1916 T2294 T2296 arg1Of ",",","
R1917 T2295 T2294 arg2Of FosB,","
R1918 T2296 T2292 arg2Of ",",(
R1919 T2296 T2298 arg1Of ",",","
R1920 T2297 T2296 arg2Of Fra-1,","
R1921 T2299 T2298 arg2Of Fra-2,","
R1922 T2300 T2292 arg3Of ),(
R1923 T2301 T2290 arg2Of and,requires
R1924 T2302 T2301 arg2Of Jun,and
R1925 T2302 T2303 arg1Of Jun,(
R1926 T2304 T2305 arg1Of c-Jun,","
R1927 T2305 T2307 arg1Of ",",","
R1928 T2306 T2305 arg2Of v-Jun,","
R1929 T2307 T2303 arg2Of ",",(
R1930 T2307 T2309 arg1Of ",",","
R1931 T2308 T2307 arg2Of JunB,","
R1932 T2310 T2309 arg2Of JunD,","
R1933 T2311 T2303 arg3Of ),(
R1934 T2314 T2312 arg2Of formation,through
R1935 T2314 T2313 arg1Of formation,the
R1936 T2314 T2315 arg1Of formation,of
R1937 T2316 T2317 arg1Of homo-,and
R1938 T2344 T2339 arg1Of sites,Both
R1939 T2344 T2340 arg1Of sites,AP-1
R1940 T2344 T2342 arg1Of sites,NF-κB
R1941 T2344 T2343 arg1Of sites,binding
R1942 T2344 T2345 arg1Of sites,have
R1943 T2344 T2346 arg1Of sites,been
R1944 T2344 T2347 arg2Of sites,identified
R1945 T2317 T2315 arg2Of and,of
R1946 T2347 T2345 arg2Of identified,have
R1947 T2347 T2346 arg2Of identified,been
R1948 T2347 T2348 arg1Of identified,in
R1949 T2318 T2317 arg2Of hetero-dimers,and
R1950 T2318 T2319 arg1Of hetero-dimers,[
R1951 T2347 T2356 arg1Of identified,[
R1952 T2347 T2359 arg1Of identified,","
R1953 T2320 T2319 arg2Of "16,17",[
R1954 T2321 T2319 arg3Of ],[
R1955 T2351 T2348 arg2Of region,in
R1956 T2351 T2349 arg1Of region,the
R1957 T2351 T2350 arg1Of region,promoter
R1958 T2351 T2352 arg1Of region,of
R1959 T2353 T2354 arg1Of IL-6,and
R1960 T2323 T2322 arg1Of and,","
R1961 T2354 T2352 arg2Of and,of
R1962 T2355 T2354 arg2Of CXCL8,and
R1963 T2357 T2356 arg2Of "12,22",[
R1964 T2324 T2323 arg2Of regulates,and
R1965 T2358 T2356 arg3Of ],[
R1966 T2325 T2324 arg2Of transcription,regulates
R1967 T2325 T2326 arg1Of transcription,of
R1968 T2363 T2362 arg1Of mechanism,the
R1969 T2363 T2364 arg2Of mechanism,by
R1970 T2363 T2365 arg1Of mechanism,which
R1971 T2363 T2372 arg1Of mechanism,is
R1972 T2363 T2375 arg1Of mechanism,clear
R1973 T2329 T2326 arg2Of range,of
R1974 T2367 T2366 arg1Of interleukins,these
R1975 T2367 T2368 arg1Of interleukins,are
R1976 T2367 T2369 arg2Of interleukins,regulated
R1977 T2369 T2364 arg1Of regulated,by
R1978 T2369 T2368 arg2Of regulated,are
R1979 T2369 T2370 arg1Of regulated,in
R1980 T2371 T2370 arg2Of T-cells,in
R1981 T2372 T2359 arg2Of is,","
R1982 T2372 T2360 arg1Of is,however
R1983 T2372 T2361 arg1Of is,","
R1984 T2372 T2373 arg1Of is,still
R1985 T2372 T2374 arg1Of is,not
R1986 T2375 T2372 arg2Of clear,is
R1987 T2376 T2377 arg1Of CXCL8,is
R1988 T2329 T2327 arg1Of range,a
R1989 T2329 T2328 arg1Of range,broad
R1990 T2329 T2330 arg1Of range,of
R1991 T2380 T2377 arg2Of chemokine,is
R1992 T2380 T2378 arg1Of chemokine,a
R1993 T2380 T2379 arg1Of chemokine,C-X-C
R1994 T2380 T2381 arg1Of chemokine,with
R1995 T2331 T2330 arg2Of genes,of
R1996 T2382 T2381 arg2Of properties,with
R1997 T2382 T2383 arg1Of properties,enabling
R1998 T2384 T2383 arg2Of it,enabling
R1999 T2384 T2386 arg1Of it,recruit
R2000 T2384 T2392 arg1Of it,activate
R2001 T2386 T2385 arg1Of recruit,to
R2002 T2386 T2390 arg1Of recruit,and
R2003 T2387 T2388 arg1Of T-cells,and
R2004 T2331 T2332 arg2Of genes,involved
R2005 T2388 T2386 arg2Of and,recruit
R2006 T2332 T2333 arg1Of involved,in
R2007 T2389 T2388 arg2Of basophils,and
R2008 T2390 T2383 arg3Of and,enabling
R2009 T2335 T2333 arg2Of responses,in
R2010 T2392 T2390 arg2Of activate,and
R2011 T2392 T2391 arg1Of activate,to
R2012 T2393 T2394 arg1Of neutrophils,and
R2013 T2394 T2392 arg2Of and,activate
R2014 T2394 T2396 arg1Of and,[
R2015 T2395 T2394 arg2Of monocytes,and
R2016 T2397 T2396 arg2Of 23,[
R2017 T2335 T2334 arg1Of responses,immune
R2018 T2398 T2396 arg3Of ],[
R2019 T2335 T2336 arg1Of responses,[
R2020 T2399 T2400 arg1Of IL-6,is
R2021 T2337 T2336 arg2Of 18-21,[
R2022 T2338 T2336 arg3Of ],[
R2023 T2400 T2410 arg1Of is,and
R2024 T2340 T2341 arg1Of AP-1,and
R2025 T2402 T2400 arg2Of cytokine,is
R2026 T2402 T2401 arg1Of cytokine,a
R2027 T2402 T2403 arg1Of cytokine,that
R2028 T2402 T2404 arg1Of cytokine,possesses
R2029 T2406 T2407 arg1Of pro-,and
R2030 T2342 T2341 arg2Of NF-κB,and
R2031 T2408 T2407 arg2Of anti-inflammatory,and
R2032 T2409 T2404 arg2Of characteristics,possesses
R2033 T2409 T2405 arg1Of characteristics,both
R2034 T2409 T2406 arg1Of characteristics,pro-
R2035 T2409 T2408 arg1Of characteristics,anti-inflammatory
R2036 T2411 T2412 arg1Of that,plays
R2037 T2412 T2410 arg2Of plays,and
R2038 T2412 T2416 arg1Of plays,in
R2039 T2412 T2421 arg1Of plays,[
R2040 T2440 T2441 arg1Of exposed,to
R2041 T2415 T2412 arg2Of role,plays
R2042 T2415 T2413 arg1Of role,a
R2043 T2415 T2414 arg1Of role,key
R2044 T2417 T2418 arg1Of haematopoiesis,and
R2045 T2442 T2443 arg1Of PMA,and
R2046 T2419 T2418 arg2Of acute-phase,and
R2047 T2420 T2416 arg2Of responses,in
R2048 T2420 T2417 arg1Of responses,haematopoiesis
R2049 T2420 T2419 arg1Of responses,acute-phase
R2050 T2422 T2421 arg2Of "24,25",[
R2051 T2423 T2421 arg3Of ],[
R2052 T2443 T2441 arg2Of and,to
R2053 T2426 T2424 arg1Of study,The
R2054 T2426 T2425 arg1Of study,present
R2055 T2426 T2427 arg1Of study,suggests
R2056 T2443 T2452 arg1Of and,in
R2057 T2444 T2445 arg2Of heat,killed
R2058 T2430 T2429 arg1Of regulation,the
R2059 T2430 T2431 arg1Of regulation,of
R2060 T2430 T2435 arg1Of regulation,is
R2061 T2430 T2436 arg1Of regulation,uncoupled
R2062 T2445 T2446 arg1Of killed,(
R2063 T2432 T2433 arg1Of CXCL8,and
R2064 T2433 T2431 arg2Of and,of
R2065 T2434 T2433 arg2Of IL-6,and
R2066 T2435 T2427 arg2Of is,suggests
R2067 T2435 T2428 arg1Of is,that
R2068 T2447 T2446 arg2Of HK,(
R2069 T2436 T2435 arg2Of uncoupled,is
R2070 T2448 T2446 arg3Of ),(
R2071 T2439 T2437 arg2Of T-cells,Using
R2072 T2439 T2438 arg1Of T-cells,Jurkat
R2073 T2439 T2440 arg2Of T-cells,exposed
R2074 T2451 T2443 arg2Of MG1655,and
R2075 T2451 T2444 arg1Of MG1655,heat
R2076 T2451 T2449 arg1Of MG1655,Escherichia
R2077 T2451 T2450 arg1Of MG1655,coli
R2078 T2453 T2452 arg2Of combination,in
R2079 T2453 T2454 arg1Of combination,with
R2080 T2455 T2454 arg2Of inhibitors,with
R2088 T2455 T2456 arg1Of inhibitors,of
R2089 T2457 T2458 arg1Of NF-κB,","
R2094 T2458 T2460 arg1Of ",",and
R2097 T2459 T2458 arg2Of JNK,","
R2098 T2460 T2456 arg2Of and,of
R2099 T2461 T2460 arg2Of PKC,and
R2100 T2463 T2437 arg1Of we,Using
R2101 T2463 T2464 arg1Of we,demonstrated
R2102 T2464 T2437 modOf demonstrated,Using
R2103 T2464 T2462 arg1Of demonstrated,","
R2104 T2466 T2467 arg1Of NF-κB,regulates
R2105 T2467 T2464 arg2Of regulates,demonstrated
R2106 T2467 T2465 arg1Of regulates,that
R2107 T2467 T2470 arg1Of regulates,while
R2108 T2469 T2467 arg2Of expression,regulates
R2109 T2469 T2468 arg1Of expression,IL-6
R2110 T2472 T2471 arg1Of regulation,the
R2111 T2472 T2473 arg1Of regulation,of
R2112 T2472 T2477 arg2Of regulation,correlated
R2113 T2474 T2473 arg2Of CXCL8,of
R2114 T2476 T2475 arg1Of closely,more
R2115 T2477 T2470 arg2Of correlated,while
R2116 T2477 T2476 arg1Of correlated,closely
R2117 T2477 T2478 arg1Of correlated,to
R2118 T2480 T2478 arg2Of activity,to
R2119 T2480 T2479 arg1Of activity,AP-1
R2120 T2482 T2481 arg1Of results,These
R2121 T2482 T2483 arg1Of results,indicate
R2122 T2485 T2486 arg1Of inhibition,of
R2123 T2485 T2488 arg1Of inhibition,is
R2124 T2487 T2486 arg2Of NF-κB,of
R2125 T2488 T2483 arg2Of is,indicate
R2126 T2488 T2484 arg1Of is,that
R2127 T2488 T2489 arg1Of is,not
R2128 T2492 T2488 arg2Of strategy,is
R2129 T2492 T2490 arg1Of strategy,an
R2130 T2492 T2491 arg1Of strategy,effective
R2131 T2492 T2493 arg1Of strategy,in
R2132 T2494 T2493 arg2Of countering,in
R2133 T2498 T2494 arg2Of activities,countering
R2134 T2498 T2495 arg1Of activities,the
R2135 T2498 T2496 arg1Of activities,high
R2136 T2498 T2497 arg1Of activities,CXCL8
R2137 T2498 T2499 arg1Of activities,in
R2138 T2500 T2499 arg2Of diseases,in
R2139 T2500 T2502 arg1Of diseases,as
R2140 T2502 T2501 arg1Of as,such
R2141 T2504 T2503 arg1Of fibrosis,cystic
R2142 T2504 T2505 arg1Of fibrosis,","
R2143 T2505 T2507 arg1Of ",",and
R2144 T2506 T2505 arg2Of AIDS,","
R2145 T2507 T2502 arg2Of and,as
R2146 T2509 T2507 arg2Of fibrosis,and
R2147 T2509 T2508 arg1Of fibrosis,pulmonary
R2763 T3418 T3419 arg1Of regulation,of
R2764 T3420 T3421 arg1Of AP-1,and
R2765 T3421 T3419 arg2Of and,of
R2766 T3423 T3421 arg2Of activation,and
R2767 T3423 T3422 arg1Of activation,NF-κB
R2768 T3426 T3424 arg1Of factors,The
R2769 T3426 T3425 arg1Of factors,transcription
R2770 T3427 T3428 arg1Of NF-κB,and
R2771 T3428 T3426 arg1Of and,factors
R2772 T3428 T3430 arg1Of and,play
R2773 T3428 T3441 arg1Of and,inducing
R2774 T3429 T3428 arg2Of AP-1,and
R2775 T3430 T3433 arg1Of play,in
R2776 T3430 T3440 arg1Of play,by
R2777 T3432 T3430 arg2Of roles,play
R2778 T3432 T3431 arg1Of roles,key
R2779 T3435 T3433 arg2Of initiation,in
R2780 T3435 T3434 arg1Of initiation,the
R2781 T3435 T3436 arg1Of initiation,of
R2782 T3439 T3436 arg2Of response,of
R2783 T3439 T3437 arg1Of response,an
R2784 T3439 T3438 arg1Of response,inflammatory
R2785 T3441 T3440 arg2Of inducing,by
R2786 T3443 T3444 arg1Of expression,and
R2787 T3444 T3441 arg2Of and,inducing
R2788 T3444 T3442 arg1Of and,the
R2789 T3444 T3446 arg1Of and,of
R2790 T3445 T3444 arg2Of secretion,and
R2791 T3447 T3448 arg1Of chemokines,and
R2792 T3448 T3446 arg2Of and,of
R2793 T3448 T3450 arg1Of and,that
R2794 T3448 T3451 arg1Of and,attract
R2795 T3448 T3453 arg1Of and,activate
R2796 T3449 T3448 arg2Of cytokines,and
R2797 T3451 T3452 arg1Of attract,and
R2798 T3453 T3452 arg2Of activate,and
R2799 T3455 T3451 arg2Of cells,attract
R2800 T3455 T3453 arg2Of cells,activate
R2801 T3455 T3454 arg1Of cells,immune
R2802 T3461 T3459 arg1Of pathways,signal
R2803 T3461 T3460 arg1Of pathways,transduction
R2804 T3461 T3462 arg1Of pathways,and
R2805 T3462 T3458 arg1Of and,the
R2806 T3462 T3471 arg1Of and,is
R2807 T3462 T3474 arg2Of and,elucidated
R2808 T3466 T3462 arg2Of induction,and
R2809 T3466 T3463 arg1Of induction,subsequent
R2810 T3466 T3464 arg1Of induction,inflammatory
R2811 T3466 T3465 arg1Of induction,cytokine
R2812 T3466 T3467 arg1Of induction,by
R2813 T3470 T3467 arg2Of factors,by
R2814 T3470 T3468 arg1Of factors,these
R2815 T3470 T3469 arg1Of factors,transcription
R2816 T3474 T3456 arg1Of elucidated,However
R2817 T3474 T3457 arg1Of elucidated,","
R2818 T3474 T3471 arg2Of elucidated,is
R2819 T3474 T3472 arg1Of elucidated,not
R2820 T3474 T3473 arg1Of elucidated,fully
R2821 T3477 T3475 arg1Of study,The
R2822 T3477 T3476 arg1Of study,present
R2823 T3477 T3478 arg1Of study,is
R2824 T3477 T3479 arg2Of study,aimed
R2825 T3479 T3478 arg2Of aimed,is
R2826 T3479 T3480 arg1Of aimed,at
R2827 T3481 T3480 arg2Of determining,at
R2828 T3483 T3481 arg2Of involvement,determining
R2829 T3483 T3482 arg1Of involvement,the
R2830 T3483 T3484 arg1Of involvement,of
R2831 T3483 T3488 arg1Of involvement,in
R2832 T3485 T3486 arg1Of AP-1,and
R2833 T3486 T3484 arg2Of and,of
R2834 T3487 T3486 arg2Of NF-κB,and
R2835 T3490 T3491 arg1Of induction,and
R2836 T3491 T3488 arg2Of and,in
R2837 T3491 T3489 arg1Of and,cytokine
R2838 T3492 T3491 arg2Of regulation,and
R2839 T3494 T3493 arg1Of treatment,PMA
R2840 T3494 T3495 arg1Of treatment,resulted
R2841 T3494 T3506 arg1Of treatment,continued
R2842 T3494 T3508 arg1Of treatment,increase
R2843 T3495 T3496 arg1Of resulted,in
R2844 T3495 T3501 arg1Of resulted,after
R2845 T3495 T3505 arg1Of resulted,and
R2846 T3498 T3496 arg2Of up-regulation,in
R2847 T3498 T3497 arg1Of up-regulation,an
R2848 T3498 T3499 arg1Of up-regulation,of
R2849 T3500 T3499 arg2Of AP-1,of
R2850 T3504 T3501 arg2Of exposure,after
R2851 T3504 T3502 arg1Of exposure,2
R2852 T3504 T3503 arg1Of exposure,h
R2853 T3506 T3505 arg2Of continued,and
R2854 T3508 T3506 arg2Of increase,continued
R2855 T3508 T3507 arg1Of increase,to
R2856 T3508 T3509 arg1Of increase,throughout
R2857 T3512 T3509 arg2Of period,throughout
R2858 T3512 T3510 arg1Of period,the
R2859 T3512 T3511 arg1Of period,analysis
R2860 T3512 T3513 arg1Of period,(
R2861 T3515 T3513 arg2Of 1a,(
R2862 T3515 T3514 arg1Of 1a,figure
R2863 T3516 T3513 arg3Of ),(
R2864 T3520 T3517 arg1Of treatment,HK
R2865 T3520 T3518 arg1Of treatment,E.
R2866 T3520 T3519 arg1Of treatment,coli
R2867 T3520 T3521 arg1Of treatment,did
R2868 T3520 T3523 arg1Of treatment,affect
R2869 T3523 T3521 arg2Of affect,did
R2870 T3523 T3522 arg1Of affect,not
R2871 T3523 T3526 arg1Of affect,in
R2872 T3525 T3523 arg2Of activation,affect
R2873 T3525 T3524 arg1Of activation,AP-1
R2874 T3528 T3526 arg2Of T-cells,in
R2875 T3528 T3527 arg1Of T-cells,Jurkat
R2876 T3528 T3529 arg1Of T-cells,(
R2877 T3531 T3529 arg2Of 1b,(
R2878 T3531 T3530 arg1Of 1b,figure
R2879 T3532 T3529 arg3Of ),(
R2880 T3534 T3533 arg1Of determine,To
R2881 T3536 T3534 arg2Of involvement,determine
R2882 T3536 T3535 arg1Of involvement,the
R2883 T3536 T3537 arg1Of involvement,of
R2884 T3539 T3537 arg2Of pathways,of
R2885 T3539 T3538 arg2Of pathways,associated
R2886 T3541 T3542 arg1Of we,exposed
R2887 T3541 T3552 arg1Of we,observed
R2888 T3542 T3544 arg1Of exposed,to
R2889 T3542 T3547 arg1Of exposed,with
R2890 T3542 T3549 arg1Of exposed,without
R2891 T3542 T3551 arg1Of exposed,and
R2892 T3543 T3542 arg2Of cells,exposed
R2893 T3546 T3544 arg2Of ionophore,to
R2894 T3546 T3545 arg1Of ionophore,Ca2+
R2895 T3547 T3548 arg1Of with,or
R2896 T3549 T3548 arg2Of without,or
R2897 T3550 T3547 arg2Of PMA,with
R2898 T3550 T3549 arg2Of PMA,without
R2899 T3551 T3533 modOf and,To
R2900 T3551 T3540 arg1Of and,","
R2901 T3552 T3551 arg2Of observed,and
R2902 T3552 T3566 arg1Of observed,while
R2903 T3555 T3552 arg2Of involvement,observed
R2904 T3555 T3553 arg1Of involvement,a
R2905 T3555 T3554 arg1Of involvement,modest
R2906 T3555 T3556 arg1Of involvement,of
R2907 T3555 T3558 arg1Of involvement,in
R2908 T3557 T3556 arg2Of Ca2+,of
R2909 T3561 T3558 arg2Of activation,in
R2910 T3561 T3559 arg1Of activation,PMA-dependent
R2911 T3561 T3560 arg1Of activation,AP-1
R2912 T3561 T3562 arg1Of activation,(
R2913 T3564 T3562 arg2Of 1c,(
R2914 T3564 T3563 arg1Of 1c,figure
R2915 T3565 T3562 arg3Of ),(
R2916 T3567 T3568 arg1Of Ca2+,alone
R2917 T3567 T3569 arg1Of Ca2+,did
R2918 T3567 T3571 arg1Of Ca2+,alter
R2919 T3571 T3566 arg2Of alter,while
R2920 T3571 T3569 arg2Of alter,did
R2921 T3571 T3570 arg1Of alter,not
R2922 T3573 T3571 arg2Of activity,alter
R2923 T3573 T3572 arg1Of activity,AP-1
R2924 T3573 T3574 arg1Of activity,(
R2925 T3575 T3574 arg2Of data,(
R2926 T3575 T3577 arg2Of data,shown
R2927 T3577 T3576 arg1Of shown,not
R2928 T3578 T3574 arg3Of ),(
R2929 T3582 T3581 arg1Of activity,AP-1
R2930 T3582 T3583 arg1Of activity,decreased
R2931 T3582 T3591 arg1Of activity,exposed
R2932 T3583 T3579 arg1Of decreased,Furthermore
R2933 T3583 T3580 arg1Of decreased,","
R2934 T3583 T3584 arg1Of decreased,in
R2935 T3583 T3590 arg1Of decreased,when
R2936 T3589 T3584 arg2Of line,in
R2937 T3589 T3585 arg1Of line,a
R2938 T3589 T3586 arg1Of line,TCR-deficient
R2939 T3589 T3587 arg1Of line,Jurkat
R2940 T3589 T3588 arg1Of line,cell
R2941 T3591 T3590 arg2Of exposed,when
R2942 T3591 T3592 arg1Of exposed,to
R2943 T3591 T3594 arg1Of exposed,compared
R2944 T3593 T3592 arg2Of PMA,to
R2945 T3595 T3594 arg2Of to,compared
R2946 T3599 T3595 arg2Of line,to
R2947 T3599 T3596 arg1Of line,the
R2948 T3599 T3597 arg1Of line,parent
R2949 T3599 T3598 arg1Of line,cell
R2950 T3599 T3600 arg1Of line,indicating
R2951 T3599 T3611 arg1Of line,(
R2952 T3602 T3603 arg1Of regulation,of
R2953 T3602 T3605 arg1Of regulation,was
R2954 T3602 T3610 arg1Of regulation,dependent
R2955 T3604 T3603 arg2Of AP-1,of
R2956 T3605 T3600 arg2Of was,indicating
R2957 T3605 T3601 arg1Of was,that
R2958 T3605 T3607 arg1Of was,partially
R2959 T3607 T3606 arg1Of partially,only
R2960 T3609 T3608 arg1Of receptor,T-cell
R2961 T3610 T3605 arg2Of dependent,was
R2962 T3610 T3609 arg1Of dependent,receptor
R2963 T3613 T3611 arg2Of 1d,(
R2964 T3613 T3612 arg1Of 1d,figure
R2965 T3614 T3611 arg3Of ),(
R2966 T3616 T3615 arg1Of levels,NF-κB
R2967 T3616 T3617 arg1Of levels,showed
R2968 T3617 T3624 arg1Of showed,after
R2969 T3620 T3617 arg2Of increase,showed
R2970 T3620 T3618 arg1Of increase,a
R2971 T3620 T3619 arg1Of increase,transient
R2972 T3620 T3621 arg1Of increase,at
R2973 T3623 T3621 arg2Of min,at
R2974 T3623 T3622 arg1Of min,1
R2975 T3625 T3624 arg2Of exposure,after
R2976 T3625 T3626 arg1Of exposure,to
R2977 T3627 T3626 arg2Of PMA,to
R2978 T3627 T3628 arg1Of PMA,(
R2979 T3630 T3628 arg2Of 2a,(
R2980 T3630 T3629 arg1Of 2a,figure
R2981 T3631 T3628 arg3Of ),(
R2982 T3635 T3634 arg1Of h,1
R2983 T3635 T3644 arg1Of h,reaching
R2984 T3637 T3636 arg2Of exposure,after
R2985 T3637 T3643 arg2Of exposure,drop
R2986 T3640 T3638 arg1Of levels,the
R2987 T3640 T3639 arg1Of levels,NF-κB
R2988 T3640 T3641 arg1Of levels,began
R2989 T3640 T3643 arg1Of levels,drop
R2990 T3643 T3641 arg2Of drop,began
R2991 T3643 T3642 arg1Of drop,to
R2992 T3644 T3632 arg1Of reaching,However
R2993 T3644 T3633 arg1Of reaching,","
R2994 T3644 T3636 arg1Of reaching,after
R2995 T3644 T3648 arg1Of reaching,by
R2996 T3647 T3644 arg2Of levels,reaching
R2997 T3647 T3645 arg1Of levels,the
R2998 T3647 T3646 arg1Of levels,lowest
R2999 T3650 T3648 arg2Of h,by
R3000 T3650 T3649 arg1Of h,6
R3001 T3650 T3651 arg1Of h,","
R3002 T3650 T3652 arg2Of h,after
R3003 T3650 T3653 arg1Of h,which
R3004 T3654 T3655 arg1Of they,increased
R3005 T3655 T3652 arg1Of increased,after
R3006 T3655 T3656 arg1Of increased,again
R3007 T3655 T3657 arg1Of increased,by
R3008 T3659 T3657 arg2Of h,by
R3009 T3659 T3658 arg1Of h,24
R3010 T3660 T3661 arg1Of Exposure,of
R3011 T3660 T3664 arg1Of Exposure,to
R3012 T3660 T3668 arg1Of Exposure,resulted
R3013 T3663 T3661 arg2Of T-cells,of
R3014 T3663 T3662 arg1Of T-cells,Jurkat
R3015 T3666 T3664 arg2Of E.,to
R3016 T3666 T3665 arg1Of E.,HK
R3017 T3666 T3667 arg1Of E.,coli
R3018 T3668 T3669 arg1Of resulted,in
R3019 T3668 T3674 arg1Of resulted,","
R3020 T3668 T3675 arg1Of resulted,with
R3021 T3668 T3688 arg1Of resulted,CFU/ml
R3022 T3673 T3669 arg2Of activation,in
R3023 T3673 T3670 arg1Of activation,a
R3024 T3673 T3671 arg1Of activation,dose-dependent
R3025 T3673 T3672 arg1Of activation,NF-κB
R3026 T3678 T3675 arg2Of activity,with
R3027 T3678 T3676 arg1Of activity,the
R3028 T3678 T3677 arg1Of activity,highest
R3029 T3678 T3679 arg2Of activity,observed
R3030 T3679 T3675 arg3Of observed,with
R3031 T3679 T3680 arg1Of observed,at
R3032 T3683 T3680 arg2Of concentration,at
R3033 T3683 T3681 arg1Of concentration,a
R3034 T3683 T3682 arg1Of concentration,relative
R3035 T3683 T3684 arg1Of concentration,of
R3036 T3685 T3684 arg2Of 5,of
R3037 T3688 T3686 arg1Of CFU/ml,×
R3038 T3688 T3687 arg1Of CFU/ml,107
R3039 T3688 T3689 arg1Of CFU/ml,(
R3040 T3691 T3689 arg2Of 2b,(
R3041 T3691 T3690 arg1Of 2b,figure
R3042 T3692 T3689 arg3Of ),(
R3043 T3695 T3693 arg1Of activation,The
R3044 T3695 T3694 arg1Of activation,time-dependent
R3045 T3695 T3696 arg1Of activation,of
R3046 T3695 T3698 arg1Of activation,by
R3047 T3695 T3702 arg1Of activation,was
R3048 T3695 T3703 arg2Of activation,assessed
R3049 T3695 T3714 arg1Of activation,showed
R3050 T3697 T3696 arg2Of NF-κB,of
R3051 T3701 T3698 arg2Of coli,by
R3052 T3701 T3699 arg1Of coli,HK
R3053 T3701 T3700 arg1Of coli,E.
R3054 T3703 T3702 arg2Of assessed,was
R3055 T3703 T3704 arg1Of assessed,further
R3056 T3703 T3713 arg1Of assessed,and
R3057 T3705 T3703 arg3Of using,assessed
R3058 T3708 T3705 arg2Of concentration,using
R3059 T3708 T3706 arg1Of concentration,the
R3060 T3708 T3707 arg1Of concentration,optimal
R3061 T3708 T3709 arg2Of concentration,obtained
R3062 T3709 T3710 arg1Of obtained,from
R3063 T3712 T3710 arg2Of 2b,from
R3064 T3712 T3711 arg1Of 2b,figure
R3065 T3714 T3713 arg2Of showed,and
R3066 T3718 T3716 arg1Of activity,the
R3067 T3718 T3717 arg1Of activity,NF-κB
R3068 T3718 T3719 arg1Of activity,increased
R3069 T3719 T3714 arg2Of increased,showed
R3070 T3719 T3715 arg1Of increased,that
R3071 T3719 T3720 arg1Of increased,after
R3072 T3722 T3720 arg2Of h,after
R3073 T3722 T3721 arg1Of h,3
R3074 T3722 T3723 arg1Of h,of
R3075 T3724 T3723 arg2Of exposure,of
R3076 T3724 T3725 arg1Of exposure,(
R3077 T3727 T3725 arg2Of 2c,(
R3078 T3727 T3726 arg1Of 2c,figure
R3079 T3728 T3725 arg3Of ),(
R3080 T3733 T3731 arg2Of Ca2+,increased
R3081 T3733 T3732 arg1Of Ca2+,intracellular
R3082 T3733 T3734 arg1Of Ca2+,reversed
R3083 T3733 T3745 arg1Of Ca2+,reduced
R3084 T3734 T3744 arg1Of reversed,and
R3085 T3739 T3734 arg2Of inhibition,reversed
R3086 T3739 T3735 arg1Of inhibition,the
R3087 T3739 T3736 arg1Of inhibition,PMA
R3088 T3739 T3737 arg1Of inhibition,dependent
R3089 T3739 T3738 arg1Of inhibition,NF-κB
R3090 T3739 T3740 arg1Of inhibition,(
R3091 T3742 T3740 arg2Of 2d,(
R3092 T3742 T3741 arg1Of 2d,figure
R3093 T3743 T3740 arg3Of ),(
R3094 T3744 T3729 arg1Of and,Furthermore
R3095 T3744 T3730 arg1Of and,","
R3096 T3745 T3744 arg2Of reduced,and
R3097 T3752 T3745 arg2Of activation,reduced
R3098 T3752 T3746 arg1Of activation,the
R3099 T3752 T3747 arg1Of activation,HK
R3100 T3752 T3748 arg1Of activation,E.
R3101 T3752 T3749 arg1Of activation,coli
R3102 T3752 T3750 arg1Of activation,-dependent
R3103 T3752 T3751 arg1Of activation,NF-κB
R3104 T3752 T3753 arg1Of activation,(
R3105 T3755 T3753 arg2Of 2e,(
R3106 T3755 T3754 arg1Of 2e,figure
R3107 T3756 T3753 arg3Of ),(
R3400 T4162 T4163 arg1Of Induction,of
R3401 T4165 T4163 arg2Of responses,of
R3402 T4165 T4164 arg1Of responses,inflammatory
R3403 T4167 T4166 arg1Of ability,The
R3404 T4167 T4168 arg1Of ability,of
R3405 T4167 T4173 arg1Of ability,coli
R3406 T4167 T4174 modOf ability,to
R3407 T4167 T4182 arg1Of ability,was
R3408 T4167 T4183 arg2Of ability,evaluated
R3409 T4169 T4170 arg1Of PMA,and
R3410 T4170 T4168 arg2Of and,of
R3411 T4171 T4170 arg2Of HK,and
R3412 T4173 T4172 arg1Of coli,E.
R3413 T4175 T4174 arg1Of induce,to
R3414 T4178 T4175 arg2Of response,induce
R3415 T4178 T4176 arg1Of response,an
R3416 T4178 T4177 arg1Of response,inflammatory
R3417 T4178 T4179 arg1Of response,in
R3418 T4181 T4179 arg2Of T-cells,in
R3419 T4181 T4180 arg1Of T-cells,Jurkat
R3420 T4183 T4182 arg2Of evaluated,was
R3421 T4183 T4184 modOf evaluated,using
R3422 T4188 T4184 arg2Of assay,using
R3423 T4188 T4185 arg1Of assay,a
R3424 T4188 T4186 arg1Of assay,multiplex
R3425 T4188 T4187 arg1Of assay,cytokine
R3426 T4188 T4189 arg1Of assay,following
R3427 T4192 T4189 arg2Of stimulation,following
R3428 T4192 T4190 arg1Of stimulation,24
R3429 T4192 T4191 arg1Of stimulation,h
R3430 T4195 T4193 arg1Of profile,The
R3431 T4195 T4194 arg1Of profile,cytokine
R3432 T4195 T4196 arg1Of profile,revealed
R3433 T4199 T4196 arg2Of induction,revealed
R3434 T4199 T4197 arg1Of induction,an
R3435 T4199 T4198 arg2Of induction,enhanced
R3436 T4199 T4200 arg1Of induction,of
R3437 T4203 T4201 arg1Of cytokines,the
R3438 T4203 T4202 arg1Of cytokines,pro-inflammatory
R3439 T4204 T4205 arg1Of IL-2,","
R3440 T4205 T4203 arg1Of ",",cytokines
R3441 T4205 T4207 arg1Of ",",","
R3442 T4206 T4205 arg2Of IL-6,","
R3443 T4207 T4209 arg1Of ",",and
R3444 T4208 T4207 arg2Of TNF,","
R3445 T4209 T4200 arg2Of and,of
R3446 T4212 T4209 arg2Of CXCL8,and
R3447 T4212 T4210 arg1Of CXCL8,the
R3448 T4212 T4211 arg1Of CXCL8,chemokine
R3449 T4214 T4213 arg1Of levels,The
R3450 T4214 T4215 arg1Of levels,of
R3451 T4214 T4220 arg1Of levels,were
R3452 T4214 T4221 arg1Of levels,unaffected
R3453 T4214 T4225 arg1Of levels,were
R3454 T4214 T4227 arg2Of levels,decreased
R3455 T4219 T4215 arg2Of IL-10,of
R3456 T4219 T4216 arg1Of IL-10,the
R3457 T4219 T4217 arg1Of IL-10,anti-inflammatory
R3458 T4219 T4218 arg1Of IL-10,cytokine
R3459 T4220 T4224 arg1Of were,but
R3460 T4221 T4220 arg2Of unaffected,were
R3461 T4221 T4222 arg1Of unaffected,by
R3462 T4223 T4222 arg2Of PMA,by
R3463 T4227 T4224 arg2Of decreased,but
R3464 T4227 T4225 arg2Of decreased,were
R3465 T4227 T4226 arg1Of decreased,significantly
R3466 T4227 T4228 arg1Of decreased,by
R3467 T4231 T4228 arg2Of coli,by
R3468 T4231 T4229 arg1Of coli,HK
R3469 T4231 T4230 arg1Of coli,E.
R3470 T4231 T4232 arg1Of coli,(
R3471 T4234 T4232 arg2Of 1,(
R3472 T4234 T4233 arg1Of 1,Table
R3473 T4235 T4232 arg3Of ),(
R3474 T4237 T4236 arg1Of results,These
R3475 T4237 T4238 arg1Of results,confirmed
R3476 T4240 T4241 arg1Of PMA,and
R3477 T4241 T4244 arg1Of and,coli
R3478 T4241 T4245 arg1Of and,induced
R3479 T4242 T4241 arg2Of HK,and
R3480 T4244 T4243 arg1Of coli,E.
R3481 T4245 T4238 arg2Of induced,confirmed
R3482 T4245 T4239 arg1Of induced,that
R3483 T4248 T4245 arg2Of response,induced
R3484 T4248 T4246 arg1Of response,an
R3485 T4248 T4247 arg1Of response,inflammatory
R3486 T4248 T4249 arg1Of response,in
R3487 T4252 T4249 arg2Of T-cells,in
R3488 T4252 T4250 arg1Of T-cells,the
R3489 T4252 T4251 arg1Of T-cells,Jurkat
R3490 T4255 T4254 arg2Of interesting,is
R3491 T4257 T4253 arg1Of note,It
R3492 T4257 T4254 arg1Of note,is
R3493 T4257 T4255 arg1Of note,interesting
R3494 T4257 T4256 arg1Of note,to
R3495 T4259 T4260 arg1Of PMA,was
R3496 T4259 T4263 arg1Of PMA,effective
R3497 T4260 T4257 arg2Of was,note
R3498 T4260 T4258 arg1Of was,that
R3499 T4262 T4261 arg1Of more,120-fold
R3500 T4263 T4260 arg2Of effective,was
R3501 T4263 T4262 arg1Of effective,more
R3502 T4263 T4264 arg1Of effective,at
R3503 T4263 T4267 arg1Of effective,than
R3504 T4265 T4264 arg2Of inducing,at
R3505 T4266 T4265 arg2Of CXCL8,inducing
R3506 T4270 T4267 arg2Of coli,than
R3507 T4270 T4268 arg1Of coli,HK
R3508 T4270 T4269 arg1Of coli,E.
R3509 T4272 T4271 arg1Of induction,PMA-dependent
R3510 T4272 T4273 arg1Of induction,of
R3511 T4272 T4279 arg1Of induction,suggests
R3512 T4274 T4275 arg1Of AP-1,and
R3513 T4275 T4273 arg2Of and,of
R3514 T4276 T4275 arg2Of down-regulation,and
R3515 T4276 T4277 arg1Of down-regulation,of
R3516 T4278 T4277 arg2Of NF-κB,of
R3517 T4281 T4279 arg2Of involvement,suggests
R3518 T4281 T4280 arg1Of involvement,an
R3519 T4281 T4282 arg1Of involvement,of
R3520 T4281 T4284 arg1Of involvement,in
R3521 T4283 T4282 arg2Of AP-1,of
R3522 T4286 T4284 arg2Of regulation,in
R3523 T4286 T4285 arg1Of regulation,CXCL8
R3524 T4287 T4288 arg1Of Determination,of
R3525 T4287 T4299 arg1Of Determination,showed
R3526 T4291 T4288 arg2Of course,of
R3527 T4291 T4289 arg1Of course,the
R3528 T4291 T4290 arg1Of course,time
R3529 T4291 T4292 arg1Of course,of
R3530 T4294 T4292 arg2Of induction,of
R3531 T4294 T4293 arg1Of induction,cytokine
R3532 T4294 T4295 arg1Of induction,in
R3533 T4296 T4295 arg2Of response,in
R3534 T4296 T4297 arg1Of response,to
R3535 T4298 T4297 arg2Of PMA,to
R3536 T4301 T4302 arg1Of CXCL8,was
R3537 T4301 T4304 arg2Of CXCL8,released
R3538 T4304 T4299 arg2Of released,showed
R3539 T4304 T4300 arg1Of released,that
R3540 T4304 T4302 arg2Of released,was
R3541 T4304 T4303 arg1Of released,already
R3542 T4304 T4305 arg1Of released,between
R3543 T4304 T4308 arg1Of released,","
R3544 T4304 T4309 arg1Of released,while
R3545 T4307 T4305 arg2Of h,between
R3546 T4307 T4306 arg1Of h,2-6
R3547 T4310 T4311 arg1Of TNF,and
R3548 T4311 T4313 arg1Of and,were
R3549 T4311 T4314 arg2Of and,released
R3550 T4312 T4311 arg2Of IL-6,and
R3551 T4314 T4309 arg2Of released,while
R3552 T4314 T4313 arg2Of released,were
R3553 T4314 T4315 arg1Of released,between
R3554 T4317 T4315 arg2Of h,between
R3555 T4317 T4316 arg1Of h,6-24
R3556 T4317 T4318 arg1Of h,(
R3557 T4319 T4318 arg2Of figure,(
R3558 T4319 T4320 arg1Of figure,3
R3559 T4321 T4318 arg3Of ),(
R3560 T4323 T4322 arg1Of results,These
R3561 T4323 T4324 arg1Of results,indicated
R3562 T4327 T4326 arg1Of cytokines,the
R3563 T4327 T4328 arg1Of cytokines,were
R3564 T4327 T4330 arg2Of cytokines,regulated
R3565 T4330 T4325 arg1Of regulated,that
R3566 T4330 T4328 arg2Of regulated,were
R3567 T4330 T4329 arg1Of regulated,differentially
R3568 T4330 T4331 arg1Of regulated,and
R3569 T4331 T4324 arg2Of and,indicated
R3570 T4332 T4331 arg2Of that,and
R3571 T4334 T4333 arg1Of release,the
R3572 T4334 T4335 arg1Of release,was
R3573 T4334 T4337 arg2Of release,associated
R3574 T4337 T4332 arg2Of associated,that
R3575 T4337 T4335 arg2Of associated,was
R3576 T4337 T4336 arg1Of associated,not
R3577 T4337 T4338 arg1Of associated,with
R3578 T4342 T4338 arg2Of induction,with
R3579 T4342 T4339 arg1Of induction,the
R3580 T4342 T4340 arg1Of induction,early
R3581 T4342 T4341 arg1Of induction,transient
R3582 T4342 T4343 arg1Of induction,of
R3583 T4344 T4343 arg2Of NF-κB,of
R3584 T4347 T4345 arg1Of induction,The
R3585 T4347 T4346 arg1Of induction,temporal
R3586 T4347 T4348 arg1Of induction,of
R3587 T4347 T4350 arg1Of induction,correlated
R3588 T4347 T4356 arg1Of induction,preceded
R3589 T4349 T4348 arg2Of AP-1,of
R3590 T4350 T4351 arg1Of correlated,to
R3591 T4350 T4355 arg1Of correlated,and
R3592 T4354 T4351 arg2Of levels,to
R3593 T4354 T4352 arg1Of levels,the
R3594 T4354 T4353 arg1Of levels,CXCL8
R3595 T4356 T4355 arg2Of preceded,and
R3596 T4358 T4359 arg1Of TNF,and
R3597 T4360 T4359 arg2Of IL-6,and
R3598 T4361 T4356 arg2Of release,preceded
R3599 T4361 T4357 arg1Of release,the
R3600 T4361 T4358 arg1Of release,TNF
R3601 T4361 T4360 arg1Of release,IL-6
R3602 T4362 T4363 arg1Of This,suggests
R3603 T4365 T4363 arg2Of association,suggests
R3604 T4365 T4364 arg1Of association,an
R3605 T4365 T4366 arg1Of association,between
R3606 T4368 T4367 arg1Of release,CXCL8
R3607 T4368 T4369 arg1Of release,and
R3608 T4369 T4366 arg2Of and,between
R3609 T4371 T4369 arg2Of signalling,and
R3610 T4371 T4370 arg1Of signalling,AP-1
R4194 T5146 T5145 arg1Of induction,Cooperative
R4195 T5146 T5147 arg1Of induction,of
R4196 T5146 T5149 arg1Of induction,by
R4197 T5148 T5147 arg2Of cytokines,of
R4198 T5150 T5151 arg1Of AP-1,and
R4199 T5151 T5149 arg2Of and,by
R4200 T5152 T5151 arg2Of NF-κB,and
R4201 T5155 T5153 arg1Of characterize,To
R4202 T5155 T5154 arg1Of characterize,further
R4203 T5157 T5155 arg2Of involvement,characterize
R4204 T5157 T5156 arg1Of involvement,the
R4205 T5157 T5158 arg1Of involvement,of
R4206 T5157 T5160 arg1Of involvement,in
R4207 T5159 T5158 arg2Of NF-κB,of
R4208 T5162 T5160 arg2Of regulation,in
R4209 T5162 T5161 arg1Of regulation,cytokine
R4210 T5164 T5155 arg1Of we,characterize
R4211 T5164 T5165 arg1Of we,treated
R4212 T5165 T5153 modOf treated,To
R4213 T5165 T5163 arg1Of treated,","
R4214 T5165 T5167 arg1Of treated,with
R4215 T5166 T5165 arg2Of cells,treated
R4216 T5171 T5167 arg2Of inhibitor,with
R4217 T5171 T5168 arg1Of inhibitor,an
R4218 T5171 T5169 arg1Of inhibitor,NF-κB
R4219 T5171 T5170 arg1Of inhibitor,activation
R4220 T5171 T5172 arg1Of inhibitor,(
R4221 T5173 T5172 arg2Of NAI,(
R4222 T5174 T5172 arg3Of ),(
R4223 T5176 T5175 arg1Of results,The
R4224 T5176 T5177 arg1Of results,showed
R4225 T5179 T5181 arg1Of NAI,down-regulated
R4226 T5179 T5191 arg1Of NAI,did
R4227 T5179 T5193 arg1Of NAI,alter
R4228 T5181 T5190 arg1Of down-regulated,and
R4229 T5183 T5181 arg2Of activation,down-regulated
R4230 T5183 T5182 arg1Of activation,NF-κB
R4231 T5183 T5184 arg1Of activation,(
R4232 T5186 T5187 arg1Of 4a,and
R4233 T5187 T5184 arg2Of and,(
R4234 T5187 T5185 arg1Of and,figures
R4235 T5188 T5187 arg2Of 4b,and
R4236 T5189 T5184 arg3Of ),(
R4237 T5190 T5177 arg2Of and,showed
R4238 T5190 T5178 arg1Of and,that
R4239 T5190 T5180 arg1Of and,selectively
R4240 T5193 T5190 arg2Of alter,and
R4241 T5193 T5191 arg2Of alter,did
R4242 T5193 T5192 arg1Of alter,not
R4243 T5195 T5193 arg2Of activity,alter
R4244 T5195 T5194 arg1Of activity,AP-1
R4245 T5195 T5196 arg1Of activity,(
R4246 T5198 T5199 arg1Of 4c,and
R4247 T5199 T5196 arg2Of and,(
R4248 T5199 T5197 arg1Of and,figures
R4249 T5200 T5199 arg2Of 4d,and
R4250 T5201 T5196 arg3Of ),(
R4251 T5202 T5203 arg1Of Exposure,of
R4252 T5202 T5206 arg1Of Exposure,to
R4253 T5202 T5208 arg1Of Exposure,resulted
R4254 T5205 T5203 arg2Of T-cells,of
R4255 T5205 T5204 arg1Of T-cells,Jurkat
R4256 T5207 T5206 arg2Of NAI,to
R4257 T5208 T5209 arg1Of resulted,in
R4258 T5208 T5218 arg1Of resulted,","
R4259 T5208 T5219 arg1Of resulted,while
R4260 T5212 T5209 arg2Of reduction,in
R4261 T5212 T5210 arg1Of reduction,a
R4262 T5212 T5211 arg1Of reduction,modest
R4263 T5212 T5213 arg1Of reduction,of
R4264 T5212 T5215 arg1Of reduction,following
R4265 T5214 T5213 arg2Of CXCL8,of
R4266 T5217 T5215 arg2Of exposure,following
R4267 T5217 T5216 arg1Of exposure,PMA
R4268 T5220 T5221 arg1Of it,did
R4269 T5220 T5223 arg1Of it,alter
R4270 T5223 T5219 arg2Of alter,while
R4271 T5223 T5221 arg2Of alter,did
R4272 T5223 T5222 arg1Of alter,not
R4273 T5226 T5223 arg2Of release,alter
R4274 T5226 T5224 arg1Of release,the
R4275 T5226 T5225 arg1Of release,CXCL8
R4276 T5226 T5227 arg1Of release,following
R4277 T5231 T5227 arg2Of exposure,following
R4278 T5231 T5228 arg1Of exposure,HK
R4279 T5231 T5229 arg1Of exposure,E.
R428 T541 T539 arg1Of regulation,Differential
R4280 T5231 T5230 arg1Of exposure,coli
R4281 T5231 T5232 arg1Of exposure,(
R4282 T5234 T5232 arg2Of 5a,(
R4283 T5234 T5233 arg1Of 5a,figure
R4284 T5235 T5232 arg3Of ),(
R4285 T5236 T5237 arg1Of NAI,did
R4286 T5236 T5239 arg1Of NAI,affect
R4287 T5239 T5237 arg2Of affect,did
R4288 T5239 T5238 arg1Of affect,not
R4289 T5239 T5246 modOf affect,indicating
R429 T541 T540 arg1Of regulation,cytokine
R4290 T5241 T5239 arg2Of expression,affect
R4291 T5241 T5240 arg1Of expression,TNF
R4292 T5241 T5242 arg1Of expression,(
R4293 T5244 T5242 arg2Of 5b,(
R4294 T5244 T5243 arg1Of 5b,figure
R4295 T5245 T5242 arg3Of ),(
R4296 T5248 T5249 arg1Of NF-κB,is
R4297 T5249 T5246 arg2Of is,indicating
R4298 T5249 T5247 arg1Of is,that
R4299 T5249 T5250 arg1Of is,not
R430 T541 T542 arg1Of regulation,by
R4300 T5253 T5249 arg2Of regulator,is
R4301 T5253 T5251 arg1Of regulator,the
R4302 T5253 T5252 arg1Of regulator,main
R4303 T5253 T5254 arg1Of regulator,of
R4304 T5253 T5258 arg1Of regulator,following
R4305 T5255 T5256 arg1Of CXCL8,or
R4306 T5256 T5254 arg2Of or,of
R4307 T5257 T5256 arg2Of TNF,or
R4308 T5260 T5261 arg1Of PMA,or
R4309 T5261 T5258 arg2Of or,following
R431 T541 T546 arg1Of regulation,in
R4310 T5261 T5259 arg1Of or,either
R4311 T5261 T5266 arg1Of or,in
R4312 T5265 T5261 arg2Of exposure,or
R4313 T5265 T5262 arg1Of exposure,HK
R4314 T5265 T5263 arg1Of exposure,E.
R4315 T5265 T5264 arg1Of exposure,coli
R4316 T5268 T5266 arg2Of T-cells,in
R4317 T5268 T5267 arg1Of T-cells,Jurkat
R4318 T5270 T5269 arg2Of contrast,In
R4319 T5272 T5273 arg1Of NAI,resulted
R432 T543 T544 arg1Of NF-κB,and
R4320 T5273 T5269 arg1Of resulted,In
R4321 T5273 T5271 arg1Of resulted,","
R4322 T5273 T5274 arg1Of resulted,in
R4323 T5273 T5297 arg1Of resulted,","
R4324 T5273 T5298 modOf resulted,suggesting
R4325 T5277 T5274 arg2Of inhibition,in
R4326 T5277 T5275 arg1Of inhibition,a
R4327 T5277 T5276 arg1Of inhibition,complete
R4328 T5277 T5278 arg1Of inhibition,of
R4329 T5277 T5280 arg1Of inhibition,following
R433 T544 T542 arg2Of and,by
R4330 T5279 T5278 arg2Of IL-6,of
R4331 T5282 T5281 arg1Of exposure,PMA
R4332 T5282 T5283 arg1Of exposure,and
R4333 T5283 T5280 arg2Of and,following
R4334 T5285 T5286 arg1Of 45,%
R4335 T5287 T5283 arg2Of inhibition,and
R4336 T5287 T5284 arg1Of inhibition,a
R4337 T5287 T5285 arg1Of inhibition,45
R4338 T5287 T5288 arg1Of inhibition,following
R4339 T5292 T5288 arg2Of exposure,following
R434 T545 T544 arg2Of AP-1,and
R4340 T5292 T5289 arg1Of exposure,HK
R4341 T5292 T5290 arg1Of exposure,E.
R4342 T5292 T5291 arg1Of exposure,coli
R4343 T5292 T5293 arg1Of exposure,(
R4344 T5295 T5293 arg2Of 5c,(
R4345 T5295 T5294 arg1Of 5c,figure
R4346 T5296 T5293 arg3Of ),(
R4347 T5300 T5298 arg2Of involvement,suggesting
R4348 T5300 T5299 arg1Of involvement,an
R4349 T5300 T5301 arg1Of involvement,of
R435 T548 T546 arg2Of T-cells,in
R4350 T5300 T5303 arg1Of involvement,in
R4351 T5302 T5301 arg2Of NF-κB,of
R4352 T5305 T5303 arg2Of regulation,in
R4353 T5305 T5304 arg1Of regulation,IL-6
R4354 T5306 T5307 arg1Of Ca2+,was
R4355 T5306 T5308 arg2Of Ca2+,observed
R4356 T5306 T5310 arg1Of Ca2+,increase
R4357 T5306 T5318 arg1Of Ca2+,reduce
R4358 T5308 T5307 arg2Of observed,was
R4359 T5308 T5325 arg1Of observed,;
R436 T548 T547 arg1Of T-cells,Jurkat
R4360 T5310 T5317 arg1Of increase,and
R4361 T5312 T5310 arg2Of activity,increase
R4362 T5312 T5311 arg1Of activity,AP-1
R4363 T5312 T5313 arg1Of activity,(
R4364 T5315 T5313 arg2Of 1c,(
R4365 T5315 T5314 arg1Of 1c,figure
R4366 T5316 T5313 arg3Of ),(
R4367 T5317 T5308 arg3Of and,observed
R4368 T5317 T5309 arg1Of and,to
R4369 T5318 T5317 arg2Of reduce,and
R437 T551 T550 arg1Of protein,Activator
R4370 T5320 T5318 arg2Of activity,reduce
R4371 T5320 T5319 arg1Of activity,NF-κB
R4372 T5320 T5321 arg1Of activity,(
R4373 T5323 T5321 arg2Of 2e,(
R4374 T5323 T5322 arg1Of 2e,figure
R4375 T5324 T5321 arg3Of ),(
R4376 T5328 T5329 arg1Of we,exposed
R4377 T5328 T5339 arg1Of we,determine
R4378 T5329 T5325 arg2Of exposed,;
R4379 T5329 T5326 arg1Of exposed,therefore
R438 T551 T552 arg1Of protein,(
R4380 T5329 T5327 arg1Of exposed,","
R4381 T5329 T5331 arg1Of exposed,to
R4382 T5329 T5335 arg1Of exposed,together
R4383 T5329 T5338 modOf exposed,to
R4384 T5330 T5329 arg2Of T-cells,exposed
R4385 T5334 T5331 arg2Of inhibitor,to
R4386 T5334 T5332 arg1Of inhibitor,a
R4387 T5334 T5333 arg1Of inhibitor,PKC
R4388 T5335 T5336 arg1Of together,with
R4389 T5337 T5336 arg2Of PMA,with
R439 T551 T555 arg1Of protein,-1
R4390 T5339 T5338 arg1Of determine,to
R4391 T5341 T5339 arg2Of effect,determine
R4392 T5341 T5340 arg1Of effect,its
R4393 T5341 T5342 arg1Of effect,on
R4394 T5344 T5342 arg2Of expression,on
R4395 T5344 T5343 arg1Of expression,cytokine
R4396 T5345 T5346 arg1Of Inhibition,of
R4397 T5345 T5348 arg1Of Inhibition,reduced
R4398 T5347 T5346 arg2Of PKC,of
R4399 T5348 T5354 arg1Of reduced,to
R440 T551 T556 arg1Of protein,and
R4400 T5348 T5357 arg1Of reduced,while
R4401 T5350 T5348 arg2Of release,reduced
R4402 T5350 T5349 arg1Of release,CXCL8
R4403 T5350 T5351 arg1Of release,from
R4404 T5353 T5351 arg2Of ng/ml,from
R4405 T5353 T5352 arg1Of ng/ml,7
R4406 T5356 T5354 arg2Of ng/ml,to
R4407 T5356 T5355 arg1Of ng/ml,3
R4408 T5358 T5359 arg1Of it,had
R4409 T5359 T5357 arg2Of had,while
R441 T553 T552 arg2Of AP,(
R4410 T5359 T5363 arg1Of had,on
R4411 T5362 T5359 arg2Of effect,had
R4412 T5362 T5360 arg1Of effect,a
R4413 T5362 T5361 arg1Of effect,modest
R4414 T5364 T5365 arg1Of IL-6,and
R4415 T5365 T5363 arg2Of and,on
R4416 T5365 T5367 arg1Of and,(
R4417 T5366 T5365 arg2Of TNF,and
R4418 T5369 T5367 arg2Of 6a-c,(
R4419 T5369 T5368 arg1Of 6a-c,figure
R442 T554 T552 arg3Of ),(
R4420 T5370 T5367 arg3Of ),(
R4421 T5371 T5372 arg1Of This,prompted
R4422 T5373 T5372 arg2Of us,prompted
R4423 T5373 T5375 arg1Of us,test
R4424 T5375 T5372 arg3Of test,prompted
R4425 T5375 T5374 arg1Of test,to
R4426 T5377 T5375 arg2Of effect,test
R4427 T5377 T5376 arg1Of effect,the
R4428 T5377 T5378 arg1Of effect,of
R4429 T5377 T5381 arg1Of effect,on
R443 T556 T564 arg1Of and,control
R4430 T5380 T5378 arg2Of inhibition,of
R4431 T5380 T5379 arg1Of inhibition,JNK
R4432 T5384 T5381 arg2Of expression,on
R4433 T5384 T5382 arg1Of expression,PMA-induced
R4434 T5384 T5383 arg1Of expression,cytokine
R4435 T5385 T5386 arg1Of JNK,is
R4436 T5385 T5387 arg2Of JNK,involved
R4437 T5387 T5386 arg2Of involved,is
R4438 T5387 T5388 arg1Of involved,in
R4439 T5387 T5410 arg1Of involved,","
R444 T560 T559 arg2Of NF,(
R4440 T5387 T5411 modOf involved,leading
R4441 T5390 T5388 arg2Of regulation,in
R4442 T5390 T5389 arg1Of regulation,the
R4443 T5390 T5391 arg1Of regulation,of
R4444 T5393 T5391 arg2Of multitude,of
R4445 T5393 T5392 arg1Of multitude,a
R4446 T5393 T5394 arg1Of multitude,of
R4447 T5397 T5395 arg1Of factors,different
R4448 T5397 T5396 arg1Of factors,transcription
R4449 T5397 T5398 arg1Of factors,","
R445 T561 T559 arg3Of ),(
R4450 T5397 T5399 arg1Of factors,including
R4451 T5397 T5406 arg1Of factors,","
R4452 T5401 T5402 arg1Of phosphorylation,and
R4453 T5402 T5399 arg2Of and,including
R4454 T5402 T5400 arg1Of and,the
R4455 T5402 T5404 arg1Of and,of
R4456 T5403 T5402 arg2Of activation,and
R4457 T5405 T5404 arg2Of c-Jun,of
R4458 T5406 T5394 arg2Of ",",of
R4459 T5407 T5408 arg1Of c-Fos,and
R446 T562 T556 arg2Of -κB,and
R4460 T5408 T5406 arg2Of and,","
R4461 T5409 T5408 arg2Of p53,and
R4462 T5411 T5412 arg1Of leading,to
R4463 T5414 T5412 arg2Of apoptosis,to
R4464 T5414 T5413 arg1Of apoptosis,cellular
R4465 T5414 T5415 arg1Of apoptosis,[
R4466 T5416 T5415 arg2Of 26,[
R4467 T5417 T5415 arg3Of ],[
R4468 T5418 T5419 arg1Of Inhibition,of
R4469 T5418 T5423 arg1Of Inhibition,resulted
R447 T562 T557 arg1Of -κB,nuclear
R4470 T5422 T5419 arg2Of pathways,of
R4471 T5422 T5420 arg1Of pathways,the
R4472 T5422 T5421 arg1Of pathways,JNK
R4473 T5423 T5424 arg1Of resulted,in
R4474 T5423 T5432 arg1Of resulted,","
R4475 T5426 T5424 arg2Of down-regulation,in
R4476 T5426 T5425 arg1Of down-regulation,a
R4477 T5426 T5427 arg1Of down-regulation,of
R4478 T5429 T5430 arg1Of CXCL8,and
R4479 T5430 T5427 arg2Of and,of
R448 T562 T558 arg1Of -κB,factor
R4480 T5430 T5428 arg1Of and,both
R4481 T5431 T5430 arg2Of IL-6,and
R4482 T5433 T5423 arg2Of while,resulted
R4483 T5436 T5434 arg1Of effect,no
R4484 T5436 T5435 arg1Of effect,clear
R4485 T5436 T5437 arg1Of effect,was
R4486 T5436 T5438 arg2Of effect,observed
R4487 T5438 T5433 arg2Of observed,while
R4488 T5438 T5437 arg2Of observed,was
R4489 T5438 T5439 arg1Of observed,on
R449 T562 T559 arg1Of -κB,(
R4490 T5441 T5439 arg2Of expression,on
R4491 T5441 T5440 arg1Of expression,TNF
R4492 T5441 T5442 arg1Of expression,(
R4493 T5444 T5442 arg2Of 6a-c,(
R4494 T5444 T5443 arg1Of 6a-c,figure
R4495 T5445 T5442 arg3Of ),(
R4496 T5446 T5447 arg1Of Analysis,of
R4497 T5446 T5456 arg1Of Analysis,showed
R4498 T5449 T5447 arg2Of levels,of
R4499 T5449 T5448 arg1Of levels,mRNA
R450 T564 T563 arg1Of control,largely
R4500 T5449 T5450 arg1Of levels,using
R4501 T5451 T5450 arg2Of RT-qPCR,using
R4502 T5451 T5452 arg1Of RT-qPCR,(
R4503 T5453 T5452 arg2Of table,(
R4504 T5453 T5454 arg1Of table,2
R4505 T5455 T5452 arg3Of ),(
R4506 T5458 T5459 arg1Of PMA,induced
R4507 T5459 T5456 arg2Of induced,showed
R4508 T5459 T5457 arg1Of induced,that
R4509 T5461 T5462 arg1Of il-6,and
R451 T564 T567 arg1Of control,","
R4510 T5463 T5462 arg2Of cxcl8,and
R4511 T5464 T5459 arg2Of mRNA,induced
R4512 T5464 T5460 arg1Of mRNA,both
R4513 T5464 T5461 arg1Of mRNA,il-6
R4514 T5464 T5463 arg1Of mRNA,cxcl8
R4515 T5464 T5465 arg1Of mRNA,(
R4516 T5466 T5467 arg1Of 5.1-fold,and
R4517 T5467 T5465 arg2Of and,(
R4518 T5467 T5470 arg1Of and,respectively
R4519 T5468 T5467 arg2Of 111.8,and
R452 T564 T568 arg1Of control,following
R4520 T5470 T5469 arg1Of respectively,fold
R4521 T5471 T5465 arg3Of ),(
R4522 T5472 T5473 arg1Of Addition,of
R4523 T5472 T5482 arg1Of Addition,reduced
R4524 T5477 T5474 arg1Of NAI,the
R4525 T5477 T5475 arg1Of NAI,NF-κB
R4526 T5477 T5476 arg1Of NAI,inhibitor
R4527 T5477 T5478 arg1Of NAI,and
R4528 T5478 T5473 arg2Of and,of
R4529 T5481 T5478 arg2Of inhibitor,and
R453 T566 T564 arg2Of activation,control
R4530 T5481 T5479 arg1Of inhibitor,the
R4531 T5481 T5480 arg1Of inhibitor,JNK
R4532 T5485 T5482 arg2Of expression,reduced
R4533 T5485 T5483 arg1Of expression,the
R4534 T5485 T5484 arg1Of expression,il-6
R4535 T5485 T5486 arg1Of expression,below
R4536 T5488 T5486 arg2Of levels,below
R4537 T5488 T5487 arg1Of levels,basal
R4538 T5490 T5489 arg2Of contrast,In
R4539 T5495 T5493 arg1Of levels,the
R454 T566 T565 arg1Of activation,T-cell
R4540 T5495 T5494 arg1Of levels,cxcl8
R4541 T5495 T5496 arg1Of levels,were
R4542 T5495 T5497 arg2Of levels,suppressed
R4543 T5497 T5492 arg2Of suppressed,while
R4544 T5497 T5496 arg2Of suppressed,were
R4545 T5501 T5497 arg1Of treatments,suppressed
R4546 T5501 T5498 arg2Of treatments,by
R4547 T5501 T5499 arg1Of treatments,the
R4548 T5501 T5500 arg1Of treatments,same
R4549 T5503 T5502 arg1Of levels,the
R455 T569 T568 arg2Of binding,following
R4550 T5503 T5504 arg1Of levels,remained
R4551 T5503 T5505 arg1Of levels,elevated
R4552 T5504 T5489 arg1Of remained,In
R4553 T5504 T5491 arg1Of remained,","
R4554 T5504 T5492 arg1Of remained,while
R4555 T5504 T5506 arg1Of remained,above
R4556 T5505 T5504 arg2Of elevated,remained
R4557 T5508 T5506 arg2Of level,above
R4558 T5508 T5507 arg1Of level,basal
R456 T569 T570 arg1Of binding,of
R457 T569 T573 arg1Of binding,to
R458 T572 T570 arg2Of antigens,of
R459 T572 T571 arg1Of antigens,foreign
R460 T576 T573 arg2Of receptor,to
R461 T576 T574 arg1Of receptor,the
R462 T576 T575 arg1Of receptor,T-cell
R463 T576 T577 arg1Of receptor,leading
R464 T577 T578 arg1Of leading,to
R465 T580 T578 arg2Of secretion,to
R466 T580 T579 arg1Of secretion,cytokine
R467 T582 T581 arg1Of levels,Elevated
R468 T582 T583 arg1Of levels,of
R469 T582 T595 arg1Of levels,are
R470 T582 T596 arg2Of levels,associated
R471 T585 T586 arg1Of cytokines,and
R472 T586 T583 arg2Of and,of
R473 T586 T584 arg1Of and,pro-inflammatory
R474 T586 T589 arg1Of and,as
R475 T587 T586 arg2Of chemokines,and
R476 T589 T588 arg1Of as,such
R477 T590 T591 arg1Of TNF,","
R478 T591 T593 arg1Of ",",and
R479 T592 T591 arg2Of IL-6,","
R480 T593 T589 arg2Of and,as
R481 T594 T593 arg2Of CXCL8,and
R482 T596 T595 arg2Of associated,are
R483 T596 T597 arg1Of associated,with
R484 T600 T597 arg2Of diseases,with
R485 T600 T598 arg1Of diseases,several
R486 T600 T599 arg1Of diseases,human
R487 T600 T601 arg1Of diseases,including
R488 T603 T602 arg1Of fibrosis,cystic
R489 T603 T604 arg1Of fibrosis,","
R490 T604 T607 arg1Of ",",and
R491 T606 T604 arg2Of fibrosis,","
R492 T606 T605 arg1Of fibrosis,pulmonary
R493 T607 T601 arg2Of and,including
R494 T608 T607 arg2Of AIDS,and
R495 T610 T609 arg1Of aim,The
R496 T610 T611 arg1Of aim,of
R4965 T6148 T6147 arg1Of inhibition,NF-κB
R4966 T6148 T6150 arg1Of inhibition,to
R4967 T6150 T6149 arg1Of to,due
R4968 T6153 T6150 arg2Of degradation,to
R4969 T6153 T6151 arg1Of degradation,PKC-dependent
R497 T610 T614 arg1Of aim,was
R4970 T6153 T6152 arg1Of degradation,Bcl10
R4971 T6156 T6154 arg1Of analysis,Western
R4972 T6156 T6155 arg1Of analysis,blot
R4973 T6156 T6157 arg1Of analysis,revealed
R4974 T6157 T6162 arg1Of revealed,after
R4975 T6157 T6179 arg1Of revealed,","
R4976 T6157 T6180 arg1Of revealed,while
R4977 T6159 T6157 arg2Of up-regulation,revealed
R4978 T6159 T6158 arg1Of up-regulation,an
R4979 T6159 T6160 arg1Of up-regulation,of
R498 T613 T611 arg2Of study,of
R4980 T6161 T6160 arg2Of phosphorylated-PKC,of
R4981 T6163 T6164 arg1Of 24,h
R4982 T6165 T6163 arg1Of treatment,24
R4983 T6165 T6166 arg1Of treatment,of
R4984 T6165 T6171 arg1Of treatment,or
R4985 T6168 T6166 arg2Of T-cells,of
R4986 T6168 T6167 arg1Of T-cells,Jurkat
R4987 T6168 T6169 arg1Of T-cells,with
R4988 T6170 T6169 arg2Of PMA,with
R4989 T6171 T6162 arg2Of or,after
R499 T613 T612 arg1Of study,this
R4990 T6174 T6171 arg2Of coli,or
R4991 T6174 T6172 arg1Of coli,HK
R4992 T6174 T6173 arg1Of coli,E.
R4993 T6174 T6175 arg1Of coli,(
R4994 T6177 T6175 arg2Of 7a,(
R4995 T6177 T6176 arg1Of 7a,figure
R4996 T6178 T6175 arg3Of ),(
R4997 T6182 T6181 arg1Of levels,IκBβ
R4998 T6182 T6183 arg1Of levels,remained
R4999 T6182 T6184 arg1Of levels,unaffected
R500 T616 T614 arg2Of investigate,was
R5000 T6183 T6180 arg2Of remained,while
R5001 T6184 T6183 arg2Of unaffected,remained
R5002 T6184 T6185 arg1Of unaffected,(
R5003 T6187 T6185 arg2Of 7b,(
R5004 T6187 T6186 arg1Of 7b,figure
R5005 T6188 T6185 arg3Of ),(
R5006 T6189 T6190 arg1Of Bcl10,is
R5007 T6193 T6190 arg2Of protein,is
R5008 T6193 T6191 arg1Of protein,a
R5009 T6193 T6192 arg1Of protein,signalling
R501 T616 T615 arg1Of investigate,to
R5010 T6193 T6194 arg1Of protein,that
R5011 T6193 T6195 arg1Of protein,acts
R5012 T6193 T6206 arg1Of protein,has
R5013 T6193 T6207 arg1Of protein,been
R5014 T6193 T6208 arg2Of protein,suggested
R5015 T6193 T6211 arg1Of protein,regulate
R5016 T6195 T6196 arg1Of acts,upstream
R5017 T6195 T6199 arg1Of acts,in
R5018 T6195 T6205 arg1Of acts,and
R5019 T6196 T6197 arg1Of upstream,of
R502 T618 T616 arg2Of role,investigate
R5020 T6198 T6197 arg2Of NF-κB,of
R5021 T6199 T6201 arg1Of in,with
R5022 T6200 T6199 arg2Of concert,in
R5023 T6202 T6203 arg1Of CARMA1,and
R5024 T6203 T6199 arg3Of and,in
R5025 T6204 T6203 arg2Of MALT1,and
R5026 T6208 T6205 arg2Of suggested,and
R5027 T6208 T6206 arg2Of suggested,has
R5028 T6208 T6207 arg2Of suggested,been
R5029 T6211 T6208 arg3Of regulate,suggested
R503 T618 T617 arg1Of role,the
R5030 T6211 T6209 arg1Of regulate,to
R5031 T6211 T6210 arg1Of regulate,directly
R5032 T6213 T6211 arg2Of activity,regulate
R5033 T6213 T6212 arg1Of activity,NF-κB
R5034 T6213 T6214 arg1Of activity,in
R5035 T6215 T6214 arg2Of T-cells,in
R5036 T6215 T6216 arg1Of T-cells,[
R5037 T6217 T6216 arg2Of 27,[
R5038 T6218 T6216 arg3Of ],[
R5039 T6222 T6221 arg1Of activation,Bcl10
R504 T618 T619 arg1Of role,of
R5040 T6222 T6223 arg1Of activation,was
R5041 T6222 T6224 arg2Of activation,evaluated
R5042 T6224 T6219 arg1Of evaluated,Therefore
R5043 T6224 T6220 arg1Of evaluated,","
R5044 T6224 T6223 arg2Of evaluated,was
R5045 T6224 T6225 arg1Of evaluated,in
R5046 T6224 T6232 arg1Of evaluated,after
R5047 T6227 T6228 arg1Of control,and
R5048 T6228 T6225 arg2Of and,in
R5049 T6228 T6226 arg1Of and,both
R505 T618 T627 arg1Of role,","
R5050 T6231 T6228 arg2Of cells,and
R5051 T6231 T6229 arg1Of cells,PMA
R5052 T6231 T6230 arg1Of cells,stimulated
R5053 T6234 T6233 arg1Of min,10
R5054 T6234 T6235 arg1Of min,","
R5055 T6235 T6238 arg1Of ",",","
R5056 T6237 T6235 arg2Of h,","
R5057 T6237 T6236 arg1Of h,1
R5058 T6238 T6242 arg1Of ",",and
R5059 T6240 T6238 arg2Of h,","
R506 T618 T628 arg1Of role,in
R5060 T6240 T6239 arg1Of h,6
R5061 T6242 T6232 arg2Of and,after
R5062 T6242 T6241 arg1Of and,","
R5063 T6244 T6242 arg2Of h,and
R5064 T6244 T6243 arg1Of h,24
R5065 T6244 T6245 arg1Of h,using
R5066 T6248 T6245 arg2Of analysis,using
R5067 T6248 T6246 arg1Of analysis,western
R5068 T6248 T6247 arg1Of analysis,blot
R5069 T6251 T6249 arg1Of levels,The
R507 T622 T619 arg2Of factors,of
R5070 T6251 T6250 arg1Of levels,Bcl10
R5071 T6251 T6252 arg1Of levels,decreased
R5072 T6252 T6253 arg1Of decreased,following
R5073 T6252 T6257 arg1Of decreased,","
R5074 T6254 T6253 arg2Of treatment,following
R5075 T6254 T6255 arg1Of treatment,with
R5076 T6256 T6255 arg2Of PMA,with
R5077 T6258 T6252 arg2Of while,decreased
R5078 T6261 T6259 arg2Of cells,in
R5079 T6261 T6260 arg1Of cells,control
R508 T622 T620 arg1Of factors,the
R5080 T6263 T6264 arg1Of Bcl10,returned
R5081 T6264 T6258 arg2Of returned,while
R5082 T6264 T6259 arg1Of returned,in
R5083 T6264 T6262 arg1Of returned,","
R5084 T6264 T6265 arg1Of returned,to
R5085 T6264 T6268 arg1Of returned,by
R5086 T6267 T6265 arg2Of levels,to
R5087 T6267 T6266 arg1Of levels,higher
R5088 T6270 T6268 arg2Of h,by
R5089 T6270 T6269 arg1Of h,24
R509 T622 T621 arg1Of factors,transcription
R5090 T6270 T6271 arg1Of h,(
R5091 T6273 T6271 arg2Of 7c,(
R5092 T6273 T6272 arg1Of 7c,figure
R5093 T6274 T6271 arg3Of ),(
R5094 T6275 T6276 arg1Of This,suggests
R5095 T6278 T6279 arg1Of Bcl10,is
R5096 T6278 T6280 arg2Of Bcl10,involved
R5097 T6280 T6276 arg2Of involved,suggests
R5098 T6280 T6277 arg1Of involved,that
R5099 T6280 T6279 arg2Of involved,is
R510 T622 T623 arg1Of factors,","
R5100 T6280 T6281 arg1Of involved,in
R5101 T6285 T6281 arg2Of inhibition,in
R5102 T6285 T6282 arg1Of inhibition,the
R5103 T6285 T6283 arg1Of inhibition,PMA
R5104 T6285 T6284 arg1Of inhibition,dependent
R5105 T6285 T6286 arg1Of inhibition,of
R5106 T6288 T6286 arg2Of activation,of
R5107 T6288 T6287 arg1Of activation,NF-κB
R511 T624 T625 arg1Of AP-1,and
R512 T625 T623 arg2Of and,","
R513 T626 T625 arg2Of NF-κB,and
R514 T629 T630 arg1Of IL-6,and
R515 T631 T630 arg2Of CXCL8,and
R516 T632 T628 arg2Of regulation,in
R517 T632 T629 arg1Of regulation,IL-6
R518 T632 T631 arg1Of regulation,CXCL8
R519 T632 T633 arg1Of regulation,in
R520 T635 T633 arg2Of T-cells,in
R521 T635 T634 arg1Of T-cells,Jurkat
R522 T639 T637 arg1Of acetate,Phorbol
R523 T639 T638 arg1Of acetate,myristate
R524 T639 T640 arg1Of acetate,(
R525 T641 T640 arg2Of PMA,(
R526 T642 T640 arg3Of ),(
R527 T643 T639 arg1Of exposure,acetate
R528 T643 T644 arg1Of exposure,resulted
R529 T644 T645 arg1Of resulted,in
R530 T644 T655 arg1Of resulted,","
R531 T644 T656 arg1Of resulted,however
R532 T644 T657 arg1Of resulted,","
R533 T647 T645 arg2Of up-regulation,in
R534 T647 T646 arg1Of up-regulation,an
R535 T647 T648 arg1Of up-regulation,of
R536 T649 T650 arg1Of AP-1,and
R537 T650 T648 arg2Of and,of
R538 T650 T652 arg1Of and,of
R539 T651 T650 arg2Of down-regulation,and
R540 T654 T652 arg2Of activity,of
R541 T654 T653 arg1Of activity,NF-κB
R542 T657 T676 arg1Of ",",without
R543 T658 T659 arg1Of exposure,to
R544 T658 T668 arg1Of exposure,resulted
R545 T660 T661 arg2Of heat,killed
R546 T661 T662 arg1Of killed,(
R547 T663 T662 arg2Of HK,(
R548 T664 T662 arg3Of ),(
R549 T667 T659 arg2Of MG1655,to
R550 T667 T660 arg1Of MG1655,heat
R551 T667 T665 arg1Of MG1655,Escherichia.
R552 T667 T666 arg1Of MG1655,coli
R553 T668 T657 arg2Of resulted,","
R554 T668 T669 arg1Of resulted,in
R555 T672 T669 arg2Of increase,in
R556 T672 T670 arg1Of increase,a
R557 T672 T671 arg1Of increase,dose-dependent
R558 T672 T673 arg1Of increase,in
R559 T675 T673 arg2Of activity,in
R560 T675 T674 arg1Of activity,NF-κB
R561 T677 T676 arg2Of affecting,without
R562 T678 T677 arg2Of AP-1,affecting
R563 T681 T679 arg1Of profile,The
R564 T681 T680 arg1Of profile,cytokine
R565 T681 T682 arg1Of profile,revealed
R566 T682 T698 arg1Of revealed,following
R567 T682 T707 arg1Of revealed,","
R568 T682 T708 arg1Of revealed,while
R569 T684 T683 arg1Of up-regulation,an
R570 T684 T685 arg1Of up-regulation,of
R571 T684 T689 arg1Of up-regulation,and
R572 T688 T685 arg2Of CXCL8,of
R573 T688 T686 arg1Of CXCL8,the
R574 T688 T687 arg1Of CXCL8,chemokine
R575 T689 T682 arg2Of and,revealed
R576 T692 T690 arg1Of cytokines,the
R577 T692 T691 arg1Of cytokines,pro-inflammatory
R578 T693 T694 arg1Of TNF,","
R579 T694 T696 arg1Of ",",and
R580 T695 T694 arg2Of IL-2,","
R581 T696 T689 arg2Of and,and
R582 T696 T692 arg1Of and,cytokines
R583 T697 T696 arg2Of IL-6,and
R584 T699 T698 arg2Of treatment,following
R585 T699 T700 arg1Of treatment,with
R586 T702 T703 arg1Of PMA,and
R587 T703 T700 arg2Of and,with
R588 T703 T701 arg1Of and,both
R589 T703 T706 arg1Of and,coli
R590 T704 T703 arg2Of HK,and
R591 T706 T705 arg1Of coli,E.
R592 T710 T709 arg1Of levels,the
R593 T710 T711 arg1Of levels,of
R594 T710 T716 arg1Of levels,were
R595 T710 T718 arg2Of levels,affected
R596 T710 T722 arg1Of levels,were
R597 T710 T724 arg2Of levels,down-regulated
R598 T715 T711 arg2Of IL-10,of
R599 T715 T712 arg1Of IL-10,the
R600 T715 T713 arg1Of IL-10,anti-inflammatory
R601 T715 T714 arg1Of IL-10,cytokine
R602 T718 T716 arg2Of affected,were
R603 T718 T717 arg1Of affected,not
R604 T718 T721 arg1Of affected,but
R605 T720 T718 arg1Of PMA,affected
R606 T720 T719 arg2Of PMA,by
R607 T721 T708 arg2Of but,while
R608 T724 T721 arg2Of down-regulated,but
R609 T724 T722 arg2Of down-regulated,were
R610 T724 T723 arg1Of down-regulated,significantly
R611 T727 T724 arg1Of E.,down-regulated
R612 T727 T725 arg2Of E.,by
R613 T727 T726 arg1Of E.,HK
R614 T727 T728 arg1Of E.,coli
R615 T730 T729 arg1Of activation,AP-1
R616 T730 T731 arg1Of activation,was
R617 T730 T733 arg2Of activation,increased
R618 T730 T740 arg1Of activation,continued
R619 T730 T742 arg1Of activation,increase
R620 T733 T731 arg2Of increased,was
R621 T733 T732 arg1Of increased,significantly
R622 T733 T736 arg1Of increased,after
R623 T733 T739 arg1Of increased,and
R624 T735 T734 arg1Of h,2
R625 T736 T735 arg1Of after,h
R626 T738 T736 arg2Of exposure,after
R627 T738 T737 arg1Of exposure,PMA
R628 T740 T739 arg2Of continued,and
R629 T742 T740 arg2Of increase,continued
R630 T742 T741 arg1Of increase,to
R631 T742 T743 arg1Of increase,thereafter
R632 T745 T744 arg2Of contrast,In
R633 T747 T748 arg1Of NF-κB,responded
R634 T748 T744 arg1Of responded,In
R635 T748 T746 arg1Of responded,","
R636 T748 T749 arg1Of responded,to
R637 T748 T752 arg1Of responded,by
R638 T751 T749 arg2Of exposure,to
R639 T751 T750 arg1Of exposure,PMA
R640 T755 T752 arg2Of up-regulation,by
R641 T755 T753 arg1Of up-regulation,a
R642 T755 T754 arg1Of up-regulation,rapid
R643 T755 T756 arg2Of up-regulation,followed
R644 T760 T756 arg1Of down-regulation,followed
R645 T760 T757 arg2Of down-regulation,by
R646 T760 T758 arg1Of down-regulation,a
R647 T760 T759 arg1Of down-regulation,subsequent
R648 T764 T761 arg2Of concentrations,Increased
R649 T764 T762 arg1Of concentrations,intracellular
R650 T764 T763 arg1Of concentrations,Ca2+
R651 T764 T765 arg1Of concentrations,countered
R652 T765 T772 arg1Of countered,","
R653 T765 T773 arg1Of countered,while
R654 T767 T765 arg2Of down-regulation,countered
R655 T767 T766 arg1Of down-regulation,the
R656 T767 T768 arg1Of down-regulation,of
R657 T767 T770 arg1Of down-regulation,by
R658 T769 T768 arg2Of NF-κB,of
R659 T771 T770 arg2Of PMA,by
R660 T775 T774 arg1Of treatment,similar
R661 T775 T776 arg1Of treatment,with
R662 T775 T779 arg1Of treatment,resulted
R663 T778 T776 arg2Of ionophore,with
R664 T778 T777 arg1Of ionophore,calcium
R665 T779 T773 arg2Of resulted,while
R666 T779 T780 arg1Of resulted,in
R667 T784 T780 arg2Of activity,in
R668 T784 T781 arg1Of activity,a
R669 T784 T782 arg2Of activity,reduced
R670 T784 T783 arg1Of activity,NF-κB
R671 T784 T785 arg1Of activity,following
R672 T786 T785 arg2Of induction,following
R673 T786 T787 arg1Of induction,with
R674 T790 T787 arg2Of coli,with
R675 T790 T788 arg1Of coli,HK
R676 T790 T789 arg1Of coli,E.
R677 T791 T793 arg1Of In,to
R678 T792 T791 arg2Of order,In
R679 T797 T791 arg3Of activation,In
R680 T797 T794 arg1Of activation,further
R681 T797 T795 arg1Of activation,study
R682 T797 T796 arg1Of activation,NF-κB
R683 T799 T800 arg1Of we,considered
R684 T800 T791 arg1Of considered,In
R685 T800 T798 arg1Of considered,","
R686 T804 T800 arg2Of proteins,considered
R687 T804 T801 arg1Of proteins,two
R688 T804 T802 arg1Of proteins,up-stream
R6880 T8442 T8443 arg1Of NF-κB,and
R6881 T8443 T8445 arg1Of and,are
R6882 T8444 T8443 arg2Of AP-1,and
R6883 T8445 T8460 arg1Of are,","
R6885 T8447 T8445 arg2Of regulators,are
R6886 T8447 T8446 arg1Of regulators,critical
R6887 T8447 T8448 arg1Of regulators,of
R6888 T8447 T8451 arg1Of regulators,","
R689 T804 T803 arg1Of proteins,signalling
R6890 T8450 T8448 arg2Of responses,of
R6891 T8450 T8449 arg1Of responses,inflammatory
R6893 T8452 T8453 arg1Of proliferation,and
R6894 T8453 T8451 arg2Of and,","
R6895 T8453 T8455 arg1Of and,of
R6896 T8454 T8453 arg2Of differentiation,and
R6898 T8456 T8455 arg2Of T-cells,of
R6899 T8456 T8457 arg1Of T-cells,[
R690 T804 T805 arg1Of proteins,","
R6901 T8458 T8457 arg2Of 28-30,[
R6902 T8459 T8457 arg3Of ],[
R6905 T8465 T8464 arg1Of transduction,signal
R6906 T8465 T8466 arg1Of transduction,and
R6908 T8466 T8463 arg1Of and,the
R6909 T8466 T8470 arg1Of and,is
R691 T806 T807 arg1Of PKC,and
R6910 T8466 T8473 arg2Of and,understood
R6911 T8469 T8466 arg2Of expression,and
R6912 T8469 T8467 arg1Of expression,subsequent
R6913 T8469 T8468 arg1Of expression,cytokine/chemokine
R6916 T8473 T8460 arg2Of understood,","
R6917 T8473 T8461 arg1Of understood,however
R6918 T8473 T8462 arg1Of understood,","
R6919 T8473 T8470 arg2Of understood,is
R692 T807 T805 arg2Of and,","
R6920 T8473 T8471 arg1Of understood,not
R6921 T8473 T8472 arg1Of understood,fully
R6922 T8475 T8474 arg1Of aim,The
R6923 T8475 T8476 arg1Of aim,of
R6924 T8475 T8480 arg1Of aim,was
R6925 T8479 T8476 arg2Of study,of
R6926 T8479 T8477 arg1Of study,the
R6927 T8479 T8478 arg1Of study,present
R6929 T8482 T8480 arg2Of investigate,was
R693 T808 T807 arg2Of Bcl10,and
R6930 T8482 T8481 arg1Of investigate,to
R6931 T8482 T8491 arg1Of investigate,in
R6932 T8483 T8484 arg1Of IL-6,and
R6934 T8485 T8484 arg2Of CXCL8,and
R6935 T8486 T8482 arg2Of regulation,investigate
R6936 T8486 T8483 arg1Of regulation,IL-6
R6937 T8486 T8485 arg1Of regulation,CXCL8
R6938 T8486 T8487 arg1Of regulation,by
R694 T810 T809 arg1Of levels,Phosphorylated-PKC
R6940 T8488 T8489 arg1Of NF-κB,and
R6941 T8489 T8487 arg2Of and,by
R6942 T8490 T8489 arg2Of AP-1,and
R6945 T8493 T8491 arg2Of T-cells,in
R6946 T8493 T8492 arg1Of T-cells,Jurkat
R6947 T8495 T8494 arg1Of results,Our
R6948 T8495 T8496 arg1Of results,demonstrated
R695 T810 T811 arg1Of levels,increased
R6952 T8498 T8499 arg1Of PMA,induced
R6954 T8499 T8496 arg2Of induced,demonstrated
R6955 T8499 T8497 arg1Of induced,that
R6956 T8499 T8502 arg1Of induced,","
R6957 T8499 T8503 modOf induced,indicating
R6958 T8501 T8499 arg2Of activation,induced
R6959 T8501 T8500 arg1Of activation,AP-1
R696 T811 T812 arg1Of increased,in
R6962 T8506 T8503 arg2Of activation,indicating
R6963 T8506 T8504 arg1Of activation,a
R6964 T8506 T8505 arg1Of activation,specific
R6965 T8506 T8507 arg1Of activation,of
R6968 T8510 T8507 arg2Of pathway,of
R6969 T8510 T8508 arg1Of pathway,the
R697 T811 T820 arg1Of increased,","
R6970 T8510 T8509 arg1Of pathway,MAPK
R6972 T8513 T8514 arg1Of we,demonstrated
R6975 T8514 T8511 arg1Of demonstrated,Furthermore
R6976 T8514 T8512 arg1Of demonstrated,","
R6978 T8519 T8516 arg1Of activation,PMA
R6979 T8519 T8517 arg1Of activation,dependent
R698 T811 T821 arg1Of increased,while
R6980 T8519 T8518 arg1Of activation,AP-1
R6981 T8519 T8520 arg1Of activation,in
R6982 T8519 T8522 arg1Of activation,was
R6983 T8519 T8523 arg2Of activation,delayed
R6984 T8519 T8530 arg2Of activation,increased
R6985 T8521 T8520 arg2Of T-cells,in
R6987 T8523 T8524 arg1Of delayed,(
R6988 T8523 T8529 arg1Of delayed,and
R699 T813 T812 arg2Of response,in
R6990 T8526 T8525 arg1Of 2,>
R6992 T8527 T8524 arg2Of h,(
R6993 T8527 T8526 arg1Of h,2
R6994 T8528 T8524 arg3Of ),(
R6995 T8529 T8514 arg2Of and,demonstrated
R6996 T8529 T8515 arg1Of and,that
R6997 T8529 T8522 arg2Of and,was
R6998 T8530 T8529 arg2Of increased,and
R6999 T8530 T8531 arg1Of increased,following
R700 T813 T814 arg1Of response,to
R7001 T8533 T8531 arg2Of treatment,following
R7002 T8533 T8532 arg1Of treatment,long-term
R7003 T8534 T8535 arg1Of MAPK,is
R7005 T8536 T8535 arg2Of one,is
R7006 T8536 T8537 arg1Of one,of
R7009 T8541 T8537 arg2Of pathways,of
R701 T815 T816 arg1Of PMA,and
R7010 T8541 T8538 arg1Of pathways,the
R7011 T8541 T8539 arg1Of pathways,main
R7012 T8541 T8540 arg1Of pathways,signalling
R7013 T8541 T8542 arg1Of pathways,in
R7014 T8543 T8542 arg2Of T-cells,in
R7015 T8543 T8544 arg1Of T-cells,that
R7016 T8543 T8545 arg1Of T-cells,regulate
R7018 T8546 T8547 arg1Of cell-,and
R702 T816 T814 arg2Of and,to
R7020 T8547 T8545 arg2Of and,regulate
R7021 T8549 T8547 arg2Of activation,and
R7022 T8549 T8548 arg1Of activation,transcriptional
R7023 T8549 T8550 arg1Of activation,[
R7025 T8551 T8550 arg2Of "31,32",[
R7026 T8552 T8550 arg3Of ],[
R7027 T8554 T8553 arg1Of studies,Several
R7028 T8554 T8555 arg1Of studies,[
R7029 T8554 T8558 arg1Of studies,have
R703 T817 T816 arg2Of HK,and
R7030 T8554 T8559 arg1Of studies,indicated
R7031 T8556 T8555 arg2Of "20,33,34",[
R7033 T8557 T8555 arg3Of ],[
R7034 T8559 T8558 arg2Of indicated,have
R7035 T8559 T8564 arg1Of indicated,in
R7037 T8561 T8559 arg2Of importance,indicated
R7038 T8561 T8560 arg1Of importance,the
R7039 T8561 T8562 arg1Of importance,of
R704 T819 T812 arg3Of coli,in
R7041 T8563 T8562 arg2Of AP-1,of
R7043 T8566 T8565 arg1Of activation,T-cell
R7044 T8566 T8567 arg1Of activation,and
R7045 T8567 T8564 arg2Of and,in
R7047 T8569 T8567 arg2Of induction,and
R7048 T8569 T8568 arg1Of induction,the
R7049 T8569 T8570 arg1Of induction,of
R705 T819 T818 arg1Of coli,E.
R7051 T8572 T8570 arg2Of responses,of
R7052 T8572 T8571 arg1Of responses,inflammatory
R7053 T8572 T8573 arg1Of responses,[
R7054 T8572 T8576 arg1Of responses,","
R7055 T8572 T8577 arg1Of responses,including
R7057 T8574 T8573 arg2Of 35,[
R7058 T8575 T8573 arg3Of ],[
R706 T823 T822 arg1Of levels,Bcl10
R7061 T8580 T8577 arg2Of release,including
R7062 T8580 T8578 arg1Of release,pro-inflammatory
R7063 T8580 T8579 arg1Of release,cytokine
R7065 T8582 T8581 arg2Of contrast,In
R7066 T8582 T8583 arg1Of contrast,to
R7068 T8584 T8583 arg2Of AP-1,to
R707 T823 T825 arg1Of levels,decreased
R7070 T8587 T8586 arg1Of activity,NF-κB
R7071 T8587 T8589 arg1Of activity,increased
R7073 T8589 T8581 arg1Of increased,In
R7074 T8589 T8585 arg1Of increased,","
R7075 T8589 T8588 arg1Of increased,rapidly
R7076 T8589 T8590 arg1Of increased,(
R7077 T8589 T8594 arg1Of increased,during
R7078 T8592 T8590 arg2Of min,(
R7079 T8592 T8591 arg1Of min,1
R708 T825 T821 arg2Of decreased,while
R7080 T8593 T8590 arg3Of ),(
R7082 T8596 T8594 arg2Of exposure,during
R7083 T8596 T8595 arg1Of exposure,PMA
R7084 T8596 T8597 arg2Of exposure,followed
R7086 T8600 T8597 arg1Of down-regulation,followed
R7087 T8600 T8598 arg2Of down-regulation,by
R7088 T8600 T8599 arg1Of down-regulation,a
R7089 T8600 T8601 arg1Of down-regulation,to
R709 T825 T824 arg1Of decreased,significantly
R7090 T8600 T8605 arg1Of down-regulation,at
R7092 T8604 T8601 arg2Of levels,to
R7093 T8604 T8602 arg1Of levels,the
R7094 T8604 T8603 arg1Of levels,lowest
R7096 T8607 T8605 arg2Of h,at
R7097 T8607 T8606 arg1Of h,6
R7098 T8611 T8610 arg2Of line,in
R7099 T8608 T8609 arg1Of This,is
R710 T825 T826 arg1Of decreased,following
R7100 T8608 T8610 arg1Of This,in
R7101 T8609 T8633 arg1Of is,but
R7102 T8610 T8609 arg2Of in,is
R7103 T8611 T8612 arg1Of line,with
R7104 T8611 T8619 arg1Of line,who
R7105 T8611 T8620 arg1Of line,demonstrated
R7106 T8613 T8614 arg1Of Park,and
R7107 T8614 T8612 arg2Of and,with
R7108 T8615 T8614 arg2Of colleagues,and
R7109 T8615 T8616 arg1Of colleagues,[
R711 T828 T826 arg2Of treatment,following
R7110 T8617 T8616 arg2Of 36,[
R7111 T8712 T8708 arg2Of stimulation,following
R7112 T8712 T8709 arg1Of stimulation,HK
R7113 T8712 T8710 arg1Of stimulation,E.
R7114 T8712 T8711 arg1Of stimulation,coli
R7115 T8714 T8713 arg2Of be,may
R7116 T8618 T8616 arg3Of ],[
R7117 T8716 T8714 arg2Of to,be
R7118 T8716 T8715 arg1Of to,due
R7119 T8620 T8627 arg1Of demonstrated,following
R712 T828 T827 arg1Of treatment,PMA
R7120 T8623 T8620 arg2Of increase,demonstrated
R7121 T8721 T8716 arg2Of calmodulin,to
R7122 T8721 T8717 arg1Of calmodulin,the
R7123 T8721 T8718 arg1Of calmodulin,Ca2+
R7124 T8721 T8719 arg1Of calmodulin,binding
R7125 T8721 T8720 arg1Of calmodulin,protein
R7126 T8721 T8722 arg1Of calmodulin,(
R7127 T8721 T8725 arg1Of calmodulin,","
R7128 T8721 T8726 arg1Of calmodulin,which
R7129 T8721 T8727 arg1Of calmodulin,has
R713 T833 T829 arg2Of inhibitor,Using
R7130 T8721 T8728 arg1Of calmodulin,been
R7131 T8721 T8729 arg2Of calmodulin,shown
R7132 T8721 T8732 arg1Of calmodulin,regulate
R7133 T8723 T8722 arg2Of CaM,(
R7134 T8724 T8722 arg3Of ),(
R7135 T8623 T8621 arg1Of increase,a
R7136 T8623 T8622 arg1Of increase,rapid
R7137 T8623 T8624 arg1Of increase,in
R7138 T8729 T8727 arg2Of shown,has
R7139 T8729 T8728 arg2Of shown,been
R714 T833 T830 arg1Of inhibitor,an
R7140 T8626 T8624 arg2Of activity,in
R7141 T8732 T8729 arg3Of regulate,shown
R7142 T8732 T8730 arg1Of regulate,to
R7143 T8732 T8731 arg1Of regulate,negatively
R7144 T8732 T8734 arg1Of regulate,when
R7145 T8733 T8732 arg2Of c-Rel,regulate
R7146 T8735 T8734 arg2Of activated,when
R7147 T8735 T8736 arg1Of activated,[
R7148 T8737 T8736 arg2Of 38,[
R7149 T8626 T8625 arg1Of activity,NF-κB
R715 T833 T831 arg1Of inhibitor,NF-κB
R7150 T8738 T8736 arg3Of ],[
R7151 T8629 T8627 arg2Of stimulation,following
R7152 T8740 T8739 arg1Of regulation,The
R7153 T8740 T8741 arg1Of regulation,of
R7154 T8740 T8745 arg2Of regulation,observed
R7155 T8740 T8750 arg1Of regulation,was
R7156 T8740 T8751 arg1Of regulation,in
R7157 T8742 T8743 arg1Of NF-κB,and
R7158 T8743 T8741 arg2Of and,of
R7159 T8744 T8743 arg2Of AP-1,and
R716 T833 T832 arg1Of inhibitor,activation
R7160 T8629 T8628 arg1Of stimulation,short-term
R7161 T8745 T8746 arg1Of observed,in
R7162 T8629 T8630 arg1Of stimulation,with
R7163 T8631 T8630 arg2Of PMA,with
R7164 T8749 T8746 arg2Of study,in
R7165 T8749 T8747 arg1Of study,the
R7166 T8749 T8748 arg1Of study,present
R7167 T8751 T8750 arg2Of in,was
R7168 T8633 T8632 arg1Of but,","
R7169 T8752 T8751 arg2Of agreement,in
R717 T835 T829 arg1Of we,Using
R7170 T8752 T8753 arg1Of agreement,with
R7171 T8755 T8753 arg2Of studies,with
R7172 T8755 T8754 arg1Of studies,earlier
R7173 T8635 T8634 arg2Of challenge,prolonged
R7174 T8756 T8757 arg1Of T-cells,produce
R7175 T8635 T8636 arg1Of challenge,resulted
R7176 T8760 T8757 arg2Of range,produce
R7177 T8760 T8758 arg1Of range,a
R7178 T8760 T8759 arg1Of range,broad
R7179 T8760 T8761 arg1Of range,of
R718 T835 T836 arg1Of we,observed
R7180 T8762 T8763 arg1Of pro-,and
R7181 T8636 T8633 arg2Of resulted,but
R7182 T8764 T8763 arg2Of anti-inflammatory,and
R7183 T8765 T8761 arg2Of cytokines,of
R7184 T8765 T8762 arg1Of cytokines,pro-
R7185 T8765 T8764 arg1Of cytokines,anti-inflammatory
R7186 T8765 T8766 arg1Of cytokines,","
R7187 T8765 T8767 arg1Of cytokines,including
R7188 T8636 T8637 arg1Of resulted,in
R7189 T8768 T8769 arg1Of IL-2,","
R719 T836 T829 modOf observed,Using
R7190 T8640 T8637 arg2Of inhibition,in
R7191 T8769 T8771 arg1Of ",",","
R7192 T8770 T8769 arg2Of IL-6,","
R7193 T8771 T8773 arg1Of ",",","
R7194 T8772 T8771 arg2Of CXCL8,","
R7195 T8773 T8775 arg1Of ",",and
R7196 T8774 T8773 arg2Of TNF,","
R7197 T8640 T8638 arg1Of inhibition,a
R7198 T8775 T8767 arg2Of and,including
R7199 T8775 T8777 arg1Of and,","
R720 T836 T834 arg1Of observed,","
R7200 T8775 T8778 arg1Of and,in
R7201 T8776 T8775 arg2Of IL-10,and
R7202 T8640 T8639 arg1Of inhibition,persistent
R7203 T8640 T8641 arg1Of inhibition,of
R7204 T8642 T8641 arg2Of NF-κB,of
R7205 T8779 T8778 arg2Of response,in
R7206 T8779 T8780 arg1Of response,to
R7207 T8781 T8782 arg1Of infections,or
R7208 T8782 T8780 arg2Of or,to
R7209 T8643 T8644 arg1Of They,showed
R721 T836 T842 arg1Of observed,while
R7210 T8785 T8782 arg2Of factors,or
R7211 T8785 T8783 arg1Of factors,other
R7212 T8785 T8784 arg1Of factors,stress
R7213 T8785 T8786 arg1Of factors,[
R7214 T8647 T8646 arg1Of inhibition,the
R7215 T8787 T8786 arg2Of 39,[
R7216 T8788 T8786 arg3Of ],[
R7217 T8790 T8789 arg1Of assessment,The
R7218 T8790 T8791 arg1Of assessment,of
R7219 T8790 T8800 arg1Of assessment,revealed
R722 T838 T836 arg2Of inhibition,observed
R7220 T8647 T8648 arg1Of inhibition,of
R7221 T8647 T8650 arg1Of inhibition,was
R7222 T8647 T8651 arg1Of inhibition,due
R7223 T8647 T8660 arg1Of inhibition,γ
R7224 T8649 T8648 arg2Of NF-κB,of
R7225 T8795 T8791 arg2Of responses,of
R7226 T8795 T8792 arg1Of responses,Jurkat
R7227 T8795 T8793 arg1Of responses,T-cell
R7228 T8795 T8794 arg1Of responses,inflammatory
R7229 T8795 T8796 arg1Of responses,(
R723 T838 T837 arg1Of inhibition,complete
R7230 T8797 T8796 arg2Of Table,(
R7231 T8797 T8798 arg1Of Table,1
R7232 T8799 T8796 arg3Of ),(
R7233 T8800 T8805 arg1Of revealed,upon
R7234 T8650 T8659 arg1Of was,and
R7235 T8804 T8800 arg2Of expression,revealed
R7236 T8804 T8801 arg1Of expression,an
R7237 T8804 T8802 arg2Of expression,enhanced
R7238 T8804 T8803 arg1Of expression,IL-2
R7239 T8651 T8650 arg2Of due,was
R724 T838 T839 arg1Of inhibition,of
R7240 T8651 T8652 arg1Of due,to
R7241 T8654 T8652 arg2Of degradation,to
R7242 T8806 T8805 arg2Of exposure,upon
R7243 T8806 T8807 arg1Of exposure,to
R7244 T8654 T8653 arg1Of degradation,PKC-dependent
R7245 T8808 T8809 arg1Of PMA,or
R7246 T8654 T8655 arg1Of degradation,of
R7247 T8809 T8807 arg2Of or,to
R7248 T8809 T8814 arg1Of or,to
R7249 T8658 T8655 arg2Of β,of
R725 T841 T839 arg2Of expression,of
R7250 T8812 T8809 arg2Of coli,or
R7251 T8812 T8810 arg1Of coli,HK
R7252 T8812 T8811 arg1Of coli,E.
R7253 T8814 T8813 arg1Of to,due
R7254 T8816 T8814 arg2Of activation,to
R7255 T8816 T8815 arg1Of activation,PKC
R7256 T8816 T8817 arg1Of activation,[
R7257 T8658 T8656 arg1Of β,IκB
R7258 T8818 T8817 arg2Of 40,[
R7259 T8658 T8657 arg1Of β,kinase
R726 T841 T840 arg1Of expression,IL-6
R7260 T8819 T8817 arg3Of ],[
R7261 T8659 T8644 arg2Of and,showed
R7262 T8821 T8820 arg2Of addition,In
R7263 T8821 T8822 arg1Of addition,to
R7264 T8659 T8645 arg1Of and,that
R7265 T8660 T8659 arg2Of γ,and
R7266 T8826 T8822 arg2Of NF-κB,to
R7267 T8826 T8823 arg1Of NF-κB,the
R7268 T8826 T8824 arg1Of NF-κB,transcription
R7269 T8826 T8825 arg1Of NF-κB,factor
R727 T844 T843 arg1Of levels,CXCL8
R7270 T8660 T8661 arg1Of γ,in
R7271 T8662 T8661 arg2Of response,in
R7272 T8830 T8828 arg1Of sites,AP-1
R7273 T8830 T8829 arg1Of sites,binding
R7274 T8830 T8831 arg1Of sites,have
R7275 T8830 T8832 arg1Of sites,been
R7276 T8830 T8833 arg2Of sites,identified
R7277 T8833 T8820 arg1Of identified,In
R7278 T8833 T8827 arg1Of identified,","
R7279 T8833 T8831 arg2Of identified,have
R728 T844 T846 arg1Of levels,decreased
R7280 T8833 T8832 arg2Of identified,been
R7281 T8833 T8834 arg1Of identified,in
R7282 T8833 T8839 arg1Of identified,","
R7283 T8662 T8663 arg1Of response,to
R7284 T8838 T8834 arg2Of region,in
R7285 T8838 T8835 arg1Of region,the
R7286 T8838 T8836 arg1Of region,IL-6
R7287 T8838 T8837 arg1Of region,promoter
R7288 T8664 T8663 arg2Of PMA,to
R7289 T8840 T8833 arg3Of indicating,identified
R729 T846 T842 arg2Of decreased,while
R7290 T8842 T8840 arg2Of regulation,indicating
R7291 T8842 T8841 arg1Of regulation,multiple
R7292 T8842 T8843 arg1Of regulation,[
R7293 T8844 T8843 arg2Of 22,[
R7294 T8671 T8667 arg1Of exposure,the
R7295 T8845 T8843 arg3Of ],[
R7296 T8846 T8847 arg1Of AP-1,and
R7297 T8847 T8849 arg1Of and,have
R7298 T8847 T8851 arg1Of and,been
R7299 T8847 T8852 arg2Of and,demonstrated
R730 T846 T845 arg1Of decreased,only
R7300 T8847 T8854 arg1Of and,regulate
R7301 T8848 T8847 arg2Of NF-κB,and
R7302 T8852 T8849 arg2Of demonstrated,have
R7303 T8852 T8850 arg1Of demonstrated,also
R7304 T8852 T8851 arg2Of demonstrated,been
R7305 T8854 T8852 arg3Of regulate,demonstrated
R7306 T8854 T8853 arg1Of regulate,to
R7307 T8856 T8854 arg2Of expression,regulate
R7308 T8856 T8855 arg1Of expression,CXCL8
R7309 T8856 T8857 arg1Of expression,during
R731 T846 T847 arg1Of decreased,by
R7310 T8856 T8862 arg1Of expression,in
R7311 T8858 T8857 arg2Of induction,during
R7312 T8858 T8859 arg1Of induction,of
R7313 T8671 T8668 arg1Of exposure,HK
R7314 T8671 T8669 arg1Of exposure,E.
R7315 T8671 T8670 arg1Of exposure,coli
R7316 T8861 T8859 arg2Of responses,of
R7317 T8861 T8860 arg1Of responses,inflammatory
R7318 T8671 T8672 arg1Of exposure,induced
R7319 T8863 T8862 arg2Of T-cells,in
R732 T846 T850 arg1Of decreased,at
R7320 T8863 T8864 arg1Of T-cells,[
R7321 T8671 T8676 arg1Of exposure,affecting
R7322 T8865 T8864 arg2Of 12,[
R7323 T8672 T8665 arg1Of induced,Interestingly
R7324 T8866 T8864 arg3Of ],[
R7325 T8672 T8666 arg1Of induced,","
R7326 T8672 T8675 arg1Of induced,without
R7327 T8674 T8672 arg2Of activation,induced
R7328 T8869 T8870 arg1Of IL-6,and
R7329 T8870 T8873 arg1Of and,is
R733 T849 T847 arg2Of %,by
R7330 T8870 T8874 arg2Of and,associated
R7331 T8872 T8870 arg2Of gene-expression,and
R7332 T8872 T8871 arg1Of gene-expression,CXCL8
R7333 T8674 T8673 arg1Of activation,NF-κB
R7334 T8676 T8675 arg2Of affecting,without
R7335 T8874 T8867 arg1Of associated,Furthermore
R7336 T8874 T8868 arg1Of associated,","
R7337 T8874 T8873 arg2Of associated,is
R7338 T8874 T8875 arg1Of associated,with
R7339 T8678 T8676 arg2Of activity,affecting
R734 T849 T848 arg1Of %,40
R7340 T8879 T8875 arg2Of response,with
R7341 T8879 T8876 arg1Of response,an
R7342 T8879 T8877 arg1Of response,early
R7343 T8879 T8878 arg1Of response,immune
R7344 T8879 T8880 arg1Of response,in
R7345 T8879 T8883 arg1Of response,[
R7346 T8882 T8880 arg2Of T-cells,in
R7347 T8882 T8881 arg1Of T-cells,Jurkat
R7348 T8678 T8677 arg1Of activity,AP-1
R7349 T8884 T8883 arg2Of 41,[
R735 T853 T850 arg2Of concentration,at
R7350 T8679 T8680 arg1Of Wang,and
R7351 T8885 T8883 arg3Of ],[
R7352 T8680 T8685 arg1Of and,reported
R7353 T8889 T8886 arg2Of study,In
R7354 T8889 T8887 arg1Of study,the
R7355 T8889 T8888 arg1Of study,present
R7356 T8680 T8691 arg1Of and,obtaining
R7357 T8681 T8680 arg2Of colleagues,and
R7358 T8892 T8893 arg1Of PMA,and
R7359 T8893 T8891 arg1Of and,both
R736 T853 T851 arg1Of concentration,the
R7360 T8893 T8897 arg1Of and,resulted
R7361 T8895 T8893 arg2Of E.,and
R7362 T8895 T8894 arg1Of E.,HK
R7363 T8895 T8896 arg1Of E.,coli
R7364 T8681 T8682 arg1Of colleagues,[
R7365 T8897 T8886 arg1Of resulted,In
R7366 T8897 T8890 arg1Of resulted,","
R7367 T8897 T8898 arg1Of resulted,in
R7368 T8897 T8903 arg1Of resulted,while
R7369 T8683 T8682 arg2Of 37,[
R737 T853 T852 arg1Of concentration,highest
R7370 T8900 T8898 arg2Of increases,in
R7371 T8900 T8899 arg1Of increases,comparable
R7372 T8900 T8901 arg1Of increases,in
R7373 T8684 T8682 arg3Of ],[
R7374 T8685 T8690 arg1Of reported,by
R7375 T8688 T8687 arg1Of inflammatory,elevated
R7376 T8902 T8901 arg2Of IL-6,in
R7377 T8904 T8905 arg1Of PMA,was
R7378 T8904 T8907 arg1Of PMA,potent
R7379 T8905 T8903 arg2Of was,while
R738 T854 T855 arg1Of Treatment,of
R7380 T8907 T8905 arg2Of potent,was
R7381 T8907 T8906 arg1Of potent,more
R7382 T8907 T8908 arg1Of potent,at
R7383 T8909 T8908 arg2Of activating,at
R7384 T8689 T8685 arg2Of response,reported
R7385 T8911 T8909 arg2Of release,activating
R7386 T8911 T8910 arg1Of release,CXCL8
R7387 T8912 T8913 arg1Of PMA,and
R7388 T8689 T8686 arg1Of response,an
R7389 T8913 T8919 arg1Of and,induced
R739 T854 T858 arg1Of Treatment,with
R7390 T8689 T8688 arg1Of response,inflammatory
R7391 T8691 T8690 arg2Of obtaining,by
R7392 T8917 T8913 arg2Of treatment,and
R7393 T8917 T8914 arg1Of treatment,HK
R7394 T8917 T8915 arg1Of treatment,E.
R7395 T8917 T8916 arg1Of treatment,coli
R7396 T8919 T8918 arg1Of induced,also
R7397 T8691 T8695 arg1Of obtaining,following
R7398 T8921 T8919 arg2Of expression,induced
R7399 T8921 T8920 arg1Of expression,TNF
R740 T854 T860 arg1Of Treatment,in
R7400 T8692 T8691 arg2Of expression,obtaining
R7401 T8922 T8923 arg1Of TNF,is
R7402 T8923 T8935 arg1Of is,and
R7403 T8924 T8923 arg2Of one,is
R7404 T8924 T8925 arg1Of one,of
R7405 T8692 T8693 arg1Of expression,of
R7406 T8694 T8693 arg2Of IL-6,of
R7407 T8928 T8925 arg2Of cytokines,of
R7408 T8928 T8926 arg1Of cytokines,the
R7409 T8928 T8927 arg1Of cytokines,first
R741 T854 T865 arg1Of Treatment,suppressed
R7410 T8928 T8929 arg2Of cytokines,induced
R7411 T8697 T8695 arg2Of exposure,following
R7412 T8931 T8929 arg1Of T-cells,induced
R7413 T8931 T8930 arg2Of T-cells,by
R7414 T8931 T8932 arg1Of T-cells,[
R7415 T8933 T8932 arg2Of 42,[
R7416 T8934 T8932 arg3Of ],[
R7417 T8697 T8696 arg1Of exposure,the
R7418 T8937 T8936 arg1Of expression,its
R7419 T8937 T8938 arg1Of expression,is
R742 T857 T855 arg2Of T-cells,of
R7420 T8937 T8939 arg2Of expression,regulated
R7421 T8697 T8698 arg1Of exposure,of
R7422 T8939 T8935 arg2Of regulated,and
R7423 T8939 T8938 arg2Of regulated,is
R7424 T8697 T8700 arg1Of exposure,to
R7425 T8699 T8698 arg2Of T-cells,of
R7426 T8939 T8946 arg1Of regulated,[
R7427 T8701 T8700 arg2Of peptidoglycan,to
R7428 T8941 T8942 arg1Of calcineurin,","
R7429 T8942 T8944 arg1Of ",",and
R743 T857 T856 arg1Of T-cells,Jurkat
R7430 T8943 T8942 arg2Of NFAT,","
R7431 T8944 T8939 arg1Of and,regulated
R7432 T8944 T8940 arg2Of and,by
R7433 T8945 T8944 arg2Of ATF-2/Jun,and
R7434 T8947 T8946 arg2Of 20,[
R7435 T8948 T8946 arg3Of ],[
R7436 T8702 T8703 arg1Of Reduction,in
R7437 T8702 T8705 arg1Of Reduction,by
R7438 T8702 T8708 arg1Of Reduction,following
R7439 T8953 T8951 arg1Of T-cells,PMA-stimulated
R744 T859 T858 arg2Of PMA,with
R7440 T8702 T8713 arg1Of Reduction,may
R7441 T8953 T8952 arg1Of T-cells,Jurkat
R7442 T8953 T8954 arg1Of T-cells,showed
R7443 T8954 T8949 arg1Of showed,However
R7444 T8954 T8950 arg1Of showed,","
R7445 T8702 T8714 arg1Of Reduction,be
R7446 T8702 T8716 arg1Of Reduction,to
R7447 T8956 T8954 arg2Of difference,showed
R7448 T8956 T8955 arg1Of difference,no
R7449 T8956 T8957 arg1Of difference,in
R745 T862 T860 arg2Of presence,in
R7450 T8704 T8703 arg2Of NF-κB,in
R7451 T8959 T8957 arg2Of expression,in
R7452 T8959 T8958 arg1Of expression,IL-10
R7453 T8959 T8960 arg1Of expression,indicating
R7454 T8707 T8705 arg2Of ionophore,by
R7455 T8964 T8960 arg2Of response,indicating
R7456 T8964 T8961 arg1Of response,an
R7457 T8964 T8962 arg2Of response,induced
R7458 T8964 T8963 arg1Of response,inflammatory
R7459 T8707 T8706 arg1Of ionophore,calcium
R746 T862 T861 arg1Of presence,the
R7460 T8999 T9001 arg1Of ",",and
R7461 T8968 T8965 arg1Of treatment,HK
R7462 T8968 T8966 arg1Of treatment,E.
R7463 T8968 T8967 arg1Of treatment,coli
R7464 T8968 T8969 arg1Of treatment,resulted
R7465 T8969 T8970 arg1Of resulted,in
R7466 T8973 T8970 arg2Of reduction,in
R7467 T8973 T8971 arg1Of reduction,a
R7468 T8973 T8972 arg1Of reduction,significant
R7469 T8973 T8974 arg1Of reduction,of
R747 T862 T863 arg1Of presence,of
R7470 T9000 T8999 arg2Of IL-5,","
R7471 T8976 T8974 arg2Of expression,of
R7472 T8976 T8975 arg1Of expression,IL-10
R7473 T9001 T8997 arg2Of and,as
R7474 T8980 T8977 arg1Of IL-10,The
R7475 T8980 T8978 arg1Of IL-10,anti-inflammatory
R7476 T8980 T8979 arg1Of IL-10,cytokine
R7477 T8980 T8981 arg1Of IL-10,is
R7478 T8980 T8982 arg2Of IL-10,known
R7479 T8980 T8984 arg1Of IL-10,inhibit
R748 T864 T863 arg2Of JNK-inhibitor,of
R7480 T8980 T9007 arg1Of IL-10,regulate
R7481 T8980 T9011 arg1Of IL-10,inducing
R7482 T9001 T9003 arg1Of and,[
R7483 T9002 T9001 arg2Of INF-γ,and
R7484 T8982 T8981 arg2Of known,is
R7485 T8984 T9006 arg1Of inhibit,and
R7486 T9004 T9003 arg2Of "39,43",[
R7487 T8986 T8985 arg1Of activation,T-cell
R7488 T8986 T8987 arg1Of activation,","
R7489 T8987 T8989 arg1Of ",",and
R749 T865 T870 arg1Of suppressed,while
R7490 T8988 T8987 arg2Of proliferation,","
R7491 T9005 T9003 arg3Of ],[
R7492 T8989 T8984 arg2Of and,inhibit
R7493 T8991 T8989 arg2Of expression,and
R7494 T8991 T8990 arg1Of expression,the
R7495 T8991 T8992 arg1Of expression,of
R7496 T9006 T8982 arg3Of and,known
R7497 T8994 T8992 arg2Of cytokines,of
R7498 T8994 T8993 arg1Of cytokines,pro-inflammatory
R7499 T8994 T8995 arg1Of cytokines,","
R750 T867 T868 arg1Of CXCL8,and
R7500 T8994 T8997 arg1Of cytokines,as
R7501 T9006 T8983 arg1Of and,to
R7502 T9007 T9006 arg2Of regulate,and
R7503 T8997 T8996 arg1Of as,such
R7504 T8998 T8999 arg1Of IL-2,","
R7505 T9007 T9010 arg1Of regulate,by
R7506 T9009 T9007 arg2Of responses,regulate
R7507 T9009 T9008 arg1Of responses,inflammatory
R7508 T9011 T9010 arg2Of inducing,by
R7509 T9096 T9097 arg1Of PKC,has
R751 T868 T865 arg2Of and,suppressed
R7510 T9096 T9098 arg1Of PKC,been
R7511 T9096 T9099 arg2Of PKC,shown
R7512 T9096 T9101 arg1Of PKC,be
R7513 T9096 T9102 arg2Of PKC,associated
R7514 T9011 T9014 arg1Of inducing,[
R7515 T9099 T9097 arg2Of shown,has
R7516 T9099 T9098 arg2Of shown,been
R7517 T9013 T9011 arg2Of anergy,inducing
R7518 T9102 T9099 arg3Of associated,shown
R7519 T9102 T9100 arg1Of associated,to
R752 T868 T866 arg1Of and,both
R7520 T9102 T9101 arg2Of associated,be
R7521 T9102 T9103 arg1Of associated,with
R7522 T9102 T9111 arg1Of associated,with
R7523 T9102 T9118 arg1Of associated,[
R7524 T9103 T9109 arg1Of with,but
R7525 T9013 T9012 arg1Of anergy,T-cell
R7526 T9105 T9103 arg2Of activation,with
R7527 T9105 T9104 arg1Of activation,the
R7528 T9105 T9106 arg1Of activation,of
R7529 T9107 T9106 arg2Of AP-1,of
R753 T869 T868 arg2Of IL-6,and
R7530 T9015 T9014 arg2Of 44,[
R7531 T9109 T9108 arg1Of but,","
R7532 T9111 T9109 arg2Of with,but
R7533 T9111 T9110 arg1Of with,not
R7534 T9113 T9111 arg2Of activation,with
R7535 T9113 T9112 arg1Of activation,NF-κB
R7536 T9113 T9114 arg1Of activation,of
R7537 T9016 T9014 arg3Of ],[
R7538 T9020 T9017 arg1Of analysis,The
R7539 T9117 T9114 arg2Of promoter,of
R754 T871 T873 arg1Of PKC-inhibitor,decreased
R7540 T9117 T9115 arg1Of promoter,the
R7541 T9117 T9116 arg1Of promoter,IL-2
R7542 T9119 T9118 arg2Of 45,[
R7543 T9120 T9118 arg3Of ],[
R7544 T9121 T9122 arg1Of Mutation,of
R7545 T9121 T9126 arg1Of Mutation,did
R7546 T9121 T9128 arg1Of Mutation,affect
R7547 T9020 T9018 arg1Of analysis,time
R7548 T9125 T9122 arg2Of site,of
R7549 T9125 T9123 arg1Of site,the
R755 T873 T870 arg2Of decreased,while
R7550 T9125 T9124 arg1Of site,NF-κB
R7551 T9020 T9019 arg1Of analysis,course
R7552 T9128 T9126 arg2Of affect,did
R7553 T9128 T9127 arg1Of affect,not
R7554 T9128 T9132 arg1Of affect,whereas
R7555 T9020 T9021 arg1Of analysis,of
R7556 T9020 T9024 arg1Of analysis,showed
R7557 T9130 T9128 arg2Of expression,affect
R7558 T9130 T9129 arg1Of expression,IL-2
R7559 T9023 T9021 arg2Of expression,of
R756 T873 T872 arg1Of decreased,primarily
R7560 T9132 T9131 arg1Of whereas,","
R7561 T9133 T9134 arg1Of mutation,of
R7562 T9133 T9142 arg1Of mutation,revoked
R7563 T9137 T9136 arg1Of site,AP-1
R7564 T9137 T9138 arg1Of site,or
R7565 T9023 T9022 arg1Of expression,cytokine
R7566 T9138 T9134 arg2Of or,of
R7567 T9138 T9135 arg1Of or,the
R7568 T9026 T9024 arg2Of correlation,showed
R7569 T9140 T9138 arg2Of depletion,or
R757 T875 T873 arg2Of expression,decreased
R7570 T9140 T9139 arg1Of depletion,PKC
R7571 T9142 T9132 arg2Of revoked,whereas
R7572 T9142 T9141 arg1Of revoked,almost
R7573 T9144 T9142 arg2Of release,revoked
R7574 T9144 T9143 arg1Of release,IL-2
R7575 T9026 T9025 arg1Of correlation,a
R7576 T9146 T9145 arg1Of observations,These
R7577 T9146 T9147 arg1Of observations,indicate
R7578 T9026 T9027 arg1Of correlation,between
R7579 T9026 T9033 arg1Of correlation,where
R758 T875 T874 arg1Of expression,CXCL8
R7580 T9151 T9149 arg1Of pathway,the
R7581 T9151 T9150 arg1Of pathway,MAPK
R7582 T9151 T9152 arg1Of pathway,and
R7583 T9152 T9157 arg1Of and,play
R7584 T9028 T9029 arg1Of AP-1,and
R7585 T9156 T9152 arg2Of AP-1,and
R7586 T9156 T9153 arg1Of AP-1,the
R7587 T9156 T9154 arg1Of AP-1,transcription
R7588 T9156 T9155 arg1Of AP-1,factor
R7589 T9157 T9147 arg2Of play,indicate
R759 T879 T877 arg1Of study,The
R7590 T9157 T9148 arg1Of play,that
R7591 T9157 T9161 arg1Of play,in
R7592 T9029 T9027 arg2Of and,between
R7593 T9157 T9170 arg1Of play,[
R7594 T9032 T9029 arg2Of CXCL8,and
R7595 T9160 T9157 arg2Of role,play
R7596 T9160 T9158 arg1Of role,an
R7597 T9160 T9159 arg1Of role,important
R7598 T9163 T9161 arg2Of induction,in
R7599 T9163 T9162 arg1Of induction,the
R760 T879 T878 arg1Of study,present
R7600 T9163 T9164 arg1Of induction,of
R7601 T9163 T9167 arg1Of induction,in
R7602 T9032 T9030 arg1Of CXCL8,the
R7603 T9032 T9031 arg1Of CXCL8,chemokine
R7604 T9166 T9164 arg2Of responses,of
R7605 T9166 T9165 arg1Of responses,inflammatory
R7606 T9035 T9034 arg1Of expression,CXCL8
R7607 T9169 T9167 arg2Of T-cells,in
R7608 T9169 T9168 arg1Of T-cells,Jurkat
R7609 T9171 T9170 arg2Of "12,20,22",[
R761 T879 T880 arg1Of study,shows
R7610 T9172 T9170 arg3Of ],[
R7611 T9035 T9036 arg1Of expression,was
R7612 T9035 T9038 arg2Of expression,elevated
R7613 T9038 T9033 arg2Of elevated,where
R7614 T9175 T9173 arg1Of results,The
R7615 T9175 T9174 arg2Of results,obtained
R7616 T9175 T9176 arg1Of results,signify
R7617 T9178 T9179 arg1Of CXCL8,was
R7618 T9178 T9181 arg2Of CXCL8,regulated
R7619 T9038 T9036 arg2Of elevated,was
R762 T882 T883 arg1Of NF-κB,regulated
R7620 T9181 T9176 arg2Of regulated,signify
R7621 T9181 T9177 arg1Of regulated,that
R7622 T9181 T9179 arg2Of regulated,was
R7623 T9181 T9180 arg1Of regulated,primarily
R7624 T9181 T9182 arg1Of regulated,through
R7625 T9038 T9037 arg1Of elevated,significantly
R7626 T9038 T9039 arg1Of elevated,already
R7627 T9038 T9040 arg1Of elevated,at
R7628 T9185 T9182 arg2Of pathway,through
R7629 T9185 T9183 arg1Of pathway,the
R763 T883 T880 arg2Of regulated,shows
R7630 T9185 T9184 arg1Of pathway,MAPK
R7631 T9038 T9043 arg1Of elevated,after
R7632 T9189 T9186 arg1Of inhibitor,The
R7633 T9189 T9187 arg1Of inhibitor,NF-κB
R7634 T9189 T9188 arg1Of inhibitor,activation
R7635 T9189 T9190 arg1Of inhibitor,(
R7636 T9189 T9193 arg1Of inhibitor,showed
R7637 T9189 T9198 arg1Of inhibitor,resulted
R7638 T9191 T9190 arg2Of NAI,(
R7639 T9042 T9040 arg2Of h,at
R764 T883 T881 arg1Of regulated,that
R7640 T9192 T9190 arg3Of ),(
R7641 T9042 T9041 arg1Of h,2-6
R7642 T9045 T9043 arg2Of exposure,after
R7643 T9193 T9195 arg1Of showed,against
R7644 T9193 T9197 arg1Of showed,and
R7645 T9194 T9193 arg2Of specificity,showed
R7646 T9045 T9044 arg1Of exposure,PMA
R7647 T9196 T9195 arg2Of NF-κB,against
R7648 T9048 T9046 arg1Of expression,The
R7649 T9198 T9197 arg2Of resulted,and
R765 T884 T885 arg1Of IL-6,but
R7650 T9198 T9199 arg1Of resulted,in
R7651 T9198 T9204 arg1Of resulted,following
R7652 T9048 T9047 arg1Of expression,CXCL8
R7653 T9048 T9049 arg1Of expression,did
R7654 T9203 T9199 arg2Of inhibition,in
R7655 T9203 T9200 arg1Of inhibition,a
R7656 T9203 T9201 arg1Of inhibition,complete
R7657 T9203 T9202 arg1Of inhibition,IL-6
R7658 T9048 T9051 arg1Of expression,correlate
R7659 T9205 T9204 arg2Of induction,following
R766 T885 T883 arg2Of but,regulated
R7660 T9205 T9206 arg1Of induction,with
R7661 T9051 T9049 arg2Of correlate,did
R7662 T9207 T9208 arg1Of PMA,and
R7663 T9208 T9206 arg2Of and,with
R7664 T9208 T9212 arg1Of and,after
R7665 T9211 T9208 arg2Of reduction,and
R7666 T9211 T9209 arg1Of reduction,significant
R7667 T9211 T9210 arg1Of reduction,IL-6
R7668 T9051 T9050 arg1Of correlate,not
R7669 T9051 T9052 arg1Of correlate,with
R767 T885 T886 arg1Of but,not
R7670 T9051 T9062 arg1Of correlate,with
R7671 T9052 T9061 arg1Of with,or
R7672 T9216 T9212 arg2Of treatment,after
R7673 T9216 T9213 arg1Of treatment,HK
R7674 T9216 T9214 arg1Of treatment,E.
R7675 T9216 T9215 arg1Of treatment,coli
R7676 T9217 T9218 arg1Of CXCL8,was
R7677 T9217 T9221 arg2Of CXCL8,regulated
R7678 T9056 T9052 arg2Of activation,with
R7679 T9221 T9218 arg2Of regulated,was
R768 T887 T885 arg2Of CXCL8,but
R7680 T9221 T9219 arg1Of regulated,highly
R7681 T9221 T9220 arg1Of regulated,up
R7682 T9221 T9224 arg1Of regulated,and
R7683 T9223 T9221 arg1Of PMA,regulated
R7684 T9223 T9222 arg2Of PMA,by
R7685 T9226 T9225 arg1Of addition,the
R7686 T9226 T9227 arg1Of addition,of
R7687 T9226 T9229 arg1Of addition,resulted
R7688 T9228 T9227 arg2Of NAI,of
R7689 T9229 T9224 arg2Of resulted,and
R769 T890 T888 arg1Of regulation,This
R7690 T9229 T9230 arg1Of resulted,in
R7691 T9056 T9053 arg1Of activation,the
R7692 T9056 T9054 arg1Of activation,early
R7693 T9056 T9055 arg1Of activation,NF-κB
R7694 T9233 T9230 arg2Of reduction,in
R7695 T9233 T9231 arg1Of reduction,a
R7696 T9233 T9232 arg1Of reduction,minor
R7697 T9233 T9234 arg1Of reduction,in
R7698 T9056 T9057 arg1Of activation,(
R7699 T9059 T9057 arg2Of min,(
R770 T890 T889 arg1Of regulation,complex
R7700 T9236 T9234 arg2Of expression,in
R7701 T9236 T9235 arg1Of expression,CXCL8
R7702 T9240 T9239 arg1Of expression,CXCL8
R7703 T9059 T9058 arg1Of min,1
R7704 T9060 T9057 arg3Of ),(
R7705 T9240 T9241 arg1Of expression,was
R7706 T9240 T9243 arg2Of expression,affected
R7707 T9062 T9061 arg2Of with,or
R7708 T9243 T9237 arg1Of affected,Furthermore
R7709 T9243 T9238 arg1Of affected,","
R771 T890 T891 arg1Of regulation,of
R7710 T9243 T9241 arg2Of affected,was
R7711 T9243 T9242 arg1Of affected,not
R7712 T9243 T9246 arg1Of affected,following
R7713 T9243 T9251 arg1Of affected,","
R7714 T9243 T9252 modOf affected,indicating
R7715 T9245 T9243 arg1Of NAI,affected
R7716 T9245 T9244 arg2Of NAI,by
R7717 T9064 T9062 arg2Of down-regulation,with
R7718 T9064 T9063 arg1Of down-regulation,the
R7719 T9250 T9246 arg2Of treatment,following
R772 T890 T893 arg1Of regulation,suggests
R7720 T9250 T9247 arg1Of treatment,HK
R7721 T9250 T9248 arg1Of treatment,E.
R7722 T9250 T9249 arg1Of treatment,coli
R7723 T9064 T9065 arg1Of down-regulation,of
R7724 T9064 T9067 arg1Of down-regulation,at
R7725 T9066 T9065 arg2Of NF-κB,of
R7726 T9254 T9252 arg2Of lack,indicating
R7727 T9254 T9253 arg1Of lack,a
R7728 T9254 T9255 arg1Of lack,of
R7729 T9254 T9257 arg1Of lack,between
R773 T892 T891 arg2Of CXCL8,of
R7730 T9256 T9255 arg2Of correlation,of
R7731 T9258 T9259 arg1Of CXCL8,and
R7732 T9259 T9257 arg2Of and,between
R7733 T9260 T9259 arg2Of NF-κB,and
R7734 T9071 T9067 arg2Of exposure,at
R7735 T9262 T9261 arg1Of analysis,Further
R7736 T9262 T9263 arg1Of analysis,of
R7737 T9262 T9266 arg1Of analysis,revealed
R7738 T9265 T9263 arg2Of expression,of
R7739 T9265 T9264 arg1Of expression,CXCL8
R774 T895 T896 arg1Of there,is
R7740 T9266 T9274 arg1Of revealed,","
R7741 T9266 T9275 modOf revealed,suggesting
R7742 T9268 T9266 arg2Of down-regulation,revealed
R7743 T9268 T9267 arg1Of down-regulation,a
R7744 T9268 T9269 arg1Of down-regulation,by
R7745 T9071 T9068 arg1Of exposure,2
R7746 T9270 T9271 arg1Of PKC-,and
R7747 T9071 T9069 arg1Of exposure,h
R7748 T9071 T9070 arg1Of exposure,post
R7749 T9272 T9271 arg2Of JNK-,and
R775 T895 T908 arg1Of there,develop
R7750 T9273 T9269 arg2Of inhibitors,by
R7751 T9273 T9270 arg1Of inhibitors,PKC-
R7752 T9273 T9272 arg1Of inhibitors,JNK-
R7753 T9073 T9074 arg1Of IL-6,and
R7754 T9275 T9284 arg1Of suggesting,","
R7755 T9275 T9285 arg1Of suggesting,respectively
R7756 T9277 T9275 arg2Of involvement,suggesting
R7757 T9277 T9276 arg1Of involvement,an
R7758 T9277 T9278 arg1Of involvement,of
R7759 T9277 T9280 arg1Of involvement,via
R776 T896 T893 arg2Of is,suggests
R7760 T9074 T9072 arg1Of and,Both
R7761 T9279 T9278 arg2Of AP-1,of
R7762 T9281 T9282 arg1Of PKC,and
R7763 T9074 T9077 arg1Of and,were
R7764 T9282 T9280 arg2Of and,via
R7765 T9283 T9282 arg2Of JNK,and
R7766 T9074 T9079 arg2Of and,regulated
R7767 T9076 T9074 arg2Of expression,and
R7768 T9286 T9287 arg1Of Analysis,of
R7769 T9286 T9291 arg1Of Analysis,confirmed
R777 T896 T894 arg1Of is,that
R7770 T9076 T9075 arg1Of expression,TNF
R7771 T9289 T9287 arg2Of expression,of
R7772 T9289 T9288 arg1Of expression,gene
R7773 T9079 T9077 arg2Of regulated,were
R7774 T9079 T9078 arg1Of regulated,up
R7775 T9079 T9080 arg1Of regulated,between
R7776 T9082 T9080 arg2Of h,between
R7777 T9291 T9290 arg1Of confirmed,further
R7778 T9293 T9294 arg1Of il-6,and
R7779 T9082 T9081 arg1Of h,6-24
R778 T896 T905 arg1Of is,in
R7780 T9294 T9296 arg1Of and,were
R7781 T9294 T9297 arg2Of and,upregulated
R7782 T9295 T9294 arg2Of cxcl8,and
R7783 T9085 T9083 arg2Of period,During
R7784 T9297 T9291 arg2Of upregulated,confirmed
R7785 T9297 T9292 arg1Of upregulated,that
R7786 T9297 T9296 arg2Of upregulated,were
R7787 T9299 T9297 arg1Of PMA,upregulated
R7788 T9299 T9298 arg2Of PMA,by
R7789 T9300 T9301 arg1Of Expression,of
R779 T898 T896 arg2Of need,is
R7790 T9300 T9303 arg1Of Expression,dropped
R7791 T9302 T9301 arg2Of il-6,of
R7792 T9303 T9304 arg1Of dropped,below
R7793 T9303 T9307 arg1Of dropped,following
R7794 T9303 T9313 arg1Of dropped,whereas
R7795 T9085 T9084 arg1Of period,this
R7796 T9087 T9088 arg1Of NF-κB,increased
R7797 T9306 T9304 arg2Of levels,below
R7798 T9306 T9305 arg1Of levels,basal
R7799 T9308 T9307 arg2Of inhibition,following
R780 T898 T897 arg1Of need,a
R7800 T9308 T9309 arg1Of inhibition,of
R7801 T9310 T9311 arg1Of NF-κB,and
R7802 T9088 T9083 arg1Of increased,During
R7803 T9311 T9309 arg2Of and,of
R7804 T9312 T9311 arg2Of JNK,and
R7805 T9088 T9086 arg1Of increased,","
R7806 T9314 T9315 arg1Of cxcl8,remained
R7807 T9088 T9089 arg1Of increased,from
R7808 T9092 T9089 arg2Of level,from
R7809 T9314 T9316 arg1Of cxcl8,elevated
R781 T898 T899 modOf need,to
R7810 T9315 T9313 arg2Of remained,whereas
R7811 T9315 T9317 arg1Of remained,above
R7812 T9315 T9326 arg1Of remained,following
R7813 T9316 T9315 arg2Of elevated,remained
R7814 T9092 T9090 arg1Of level,its
R7815 T9092 T9091 arg1Of level,minimum
R7816 T9092 T9093 arg1Of level,at
R7817 T9319 T9317 arg2Of levels,above
R7818 T9319 T9318 arg1Of levels,basal
R7819 T9319 T9320 arg1Of levels,(
R782 T901 T899 arg1Of evaluate,to
R7820 T9321 T9322 arg1Of 16.5-fold,and
R7821 T9322 T9320 arg2Of and,(
R7822 T9322 T9324 arg1Of and,respectively
R7823 T9095 T9093 arg2Of h,at
R7824 T9323 T9322 arg2Of 7.1-fold,and
R7825 T9325 T9320 arg3Of ),(
R7826 T9095 T9094 arg1Of h,6
R7827 T9387 T9384 arg1Of NF-κB,The
R7828 T9329 T9326 arg2Of treatment,following
R7829 T9329 T9327 arg1Of treatment,the
R783 T901 T900 arg1Of evaluate,further
R7830 T9329 T9328 arg1Of treatment,same
R7831 T9332 T9333 arg1Of inhibition,of
R7832 T9332 T9335 arg1Of inhibition,did
R7833 T9332 T9337 arg1Of inhibition,result
R7834 T9334 T9333 arg2Of PKC,of
R7835 T9337 T9330 arg1Of result,Furthermore
R7836 T9337 T9331 arg1Of result,","
R7837 T9337 T9335 arg2Of result,did
R7838 T9337 T9336 arg1Of result,not
R7839 T9337 T9338 arg1Of result,in
R784 T904 T901 arg2Of pathways,evaluate
R7840 T9337 T9346 arg1Of result,","
R7841 T9337 T9347 arg1Of result,which
R7842 T9337 T9348 arg1Of result,is
R7843 T9387 T9385 arg1Of NF-κB,transcription
R7844 T9337 T9349 arg1Of result,in
R7845 T9387 T9386 arg1Of NF-κB,factor
R7846 T9387 T9388 arg1Of NF-κB,is
R7847 T9387 T9389 arg1Of NF-κB,responsible
R7848 T9389 T9388 arg2Of responsible,is
R7849 T9341 T9338 arg2Of decrease,in
R785 T904 T902 arg1Of pathways,the
R7850 T9341 T9339 arg1Of decrease,a
R7851 T9341 T9340 arg1Of decrease,significant
R7852 T9341 T9342 arg1Of decrease,of
R7853 T9343 T9344 arg1Of il-6,or
R7854 T9344 T9342 arg2Of or,of
R7855 T9345 T9344 arg2Of cxcl8,or
R7856 T9389 T9390 arg1Of responsible,for
R7857 T9394 T9390 arg2Of response,for
R7858 T9349 T9348 arg2Of in,is
R7859 T9350 T9349 arg2Of accordance,in
R786 T904 T903 arg1Of pathways,signalling
R7860 T9350 T9351 arg1Of accordance,with
R7861 T9353 T9351 arg2Of data,with
R7862 T9353 T9352 arg1Of data,protein
R7863 T9353 T9354 arg1Of data,(
R7864 T9394 T9391 arg1Of response,a
R7865 T9355 T9354 arg2Of figure,(
R7866 T9355 T9356 arg1Of figure,6
R7867 T9394 T9392 arg1Of response,rapid
R7868 T9394 T9393 arg1Of response,immune
R7869 T9357 T9354 arg3Of ),(
R787 T906 T905 arg2Of order,in
R7870 T9394 T9395 arg1Of response,which
R7871 T9359 T9358 arg1Of results,These
R7872 T9359 T9360 arg1Of results,suggest
R7873 T9394 T9396 arg1Of response,is
R7874 T9394 T9397 arg2Of response,followed
R7875 T9362 T9363 arg1Of NF-κB,is
R7876 T9362 T9364 arg2Of NF-κB,involved
R7877 T9397 T9396 arg2Of followed,is
R7878 T9364 T9360 arg2Of involved,suggest
R7879 T9364 T9361 arg1Of involved,that
R788 T908 T905 arg3Of develop,in
R7880 T9364 T9363 arg2Of involved,is
R7881 T9364 T9365 arg1Of involved,in
R7882 T9364 T9370 arg1Of involved,while
R7883 T9367 T9366 arg1Of regulation,IL-6
R7884 T9367 T9368 arg1Of regulation,and
R7885 T9368 T9365 arg2Of and,in
R7886 T9369 T9368 arg2Of release,and
R7887 T9371 T9372 arg1Of it,is
R7888 T9371 T9374 arg2Of it,required
R7889 T9400 T9397 arg1Of increase,followed
R789 T908 T907 arg1Of develop,to
R7890 T9374 T9370 arg2Of required,while
R7891 T9374 T9372 arg2Of required,is
R7892 T9374 T9373 arg1Of required,not
R7893 T9374 T9375 arg1Of required,for
R7894 T9377 T9375 arg2Of expression,for
R7895 T9377 T9376 arg1Of expression,the
R7896 T9377 T9378 arg1Of expression,of
R7897 T9377 T9380 arg1Of expression,in
R7898 T9400 T9398 arg2Of increase,by
R7899 T9379 T9378 arg2Of CXCL8,of
R790 T910 T908 arg2Of treatment,develop
R7900 T9400 T9399 arg1Of increase,an
R7901 T9400 T9401 arg1Of increase,in
R7902 T9402 T9401 arg2Of transcription,in
R7903 T9383 T9380 arg2Of cells,in
R7904 T9383 T9381 arg1Of cells,Jurkat
R7905 T9383 T9382 arg1Of cells,T
R7906 T9402 T9403 arg1Of transcription,of
R7907 T9402 T9406 arg1Of transcription,inhibiting
R7908 T9404 T9403 arg2Of IκB,of
R7909 T9406 T9405 arg1Of inhibiting,thus
R791 T910 T909 arg1Of treatment,new
R7910 T9407 T9406 arg2Of NF-κB,inhibiting
R7911 T9484 T9481 arg2Of and,via
R7912 T9484 T9482 arg1Of and,the
R7913 T9485 T9484 arg2Of PKC,and
R7914 T9407 T9408 arg1Of NF-κB,[
R7915 T9486 T9487 arg1Of resulted,in
R7916 T9409 T9408 arg2Of 46,[
R7917 T9410 T9408 arg3Of ],[
R7918 T9490 T9487 arg2Of down-regulation,in
R7919 T9490 T9488 arg1Of down-regulation,a
R792 T910 T911 arg1Of treatment,for
R7920 T9490 T9489 arg1Of down-regulation,concomitant
R7921 T9490 T9491 arg1Of down-regulation,of
R7922 T9492 T9491 arg2Of NF-κB,of
R7923 T9493 T9494 arg1Of They,suggested
R7924 T9411 T9412 arg1Of Activation,of
R7925 T9496 T9497 arg1Of Bcl10,is
R7926 T9496 T9499 arg2Of Bcl10,activated
R7927 T9411 T9414 arg1Of Activation,in
R7928 T9411 T9417 arg1Of Activation,is
R7929 T9411 T9418 arg1Of Activation,dependent
R793 T912 T911 arg2Of diseases,for
R7930 T9499 T9495 arg1Of activated,that
R7931 T9499 T9497 arg2Of activated,is
R7932 T9499 T9498 arg1Of activated,initially
R7933 T9499 T9502 arg1Of activated,but
R7934 T9501 T9499 arg1Of TCR/PKC,activated
R7935 T9501 T9500 arg2Of TCR/PKC,by
R7936 T9502 T9494 arg2Of but,suggested
R7937 T9503 T9502 arg2Of that,but
R7938 T9413 T9412 arg2Of NF-κB,of
R7939 T9505 T9504 arg1Of activation,continued
R794 T912 T913 arg1Of diseases,with
R7940 T9505 T9506 arg1Of activation,(
R7941 T9505 T9511 arg1Of activation,promotes
R7942 T9416 T9414 arg2Of T-cells,in
R7943 T9508 T9507 arg1Of 1,>
R7944 T9509 T9506 arg2Of h,(
R7945 T9509 T9508 arg1Of h,1
R7946 T9510 T9506 arg3Of ),(
R7947 T9511 T9503 arg2Of promotes,that
R7948 T9416 T9415 arg1Of T-cells,Jurkat
R7949 T9513 T9511 arg2Of degradation,promotes
R795 T916 T913 arg2Of levels,with
R7950 T9513 T9512 arg1Of degradation,its
R7951 T9514 T9515 arg1Of Narayan,and
R7952 T9418 T9417 arg2Of dependent,is
R7953 T9515 T9517 arg1Of and,[
R7954 T9515 T9520 arg1Of and,suggested
R7955 T9516 T9515 arg2Of colleagues,and
R7956 T9518 T9517 arg2Of 27,[
R7957 T9418 T9419 arg1Of dependent,on
R7958 T9519 T9517 arg3Of ],[
R7959 T9421 T9419 arg2Of activation,on
R796 T916 T914 arg1Of levels,elevated
R7960 T9522 T9523 arg1Of deletion,in
R7961 T9522 T9531 arg1Of deletion,impairs
R7962 T9524 T9523 arg2Of any,in
R7963 T9524 T9525 arg1Of any,of
R7964 T9421 T9420 arg1Of activation,Bcl10
R7965 T9421 T9422 arg1Of activation,","
R7966 T9421 T9423 arg1Of activation,which
R7967 T9421 T9426 arg1Of activation,is
R7968 T9421 T9427 arg2Of activation,regulated
R7969 T9530 T9525 arg2Of proteins,of
R797 T916 T915 arg1Of levels,CXCL8
R7970 T9530 T9526 arg1Of proteins,the
R7971 T9530 T9527 arg1Of proteins,three
R7972 T9530 T9528 arg1Of proteins,CBM
R7973 T9530 T9529 arg1Of proteins,complex
R7974 T9531 T9520 arg2Of impairs,suggested
R7975 T9531 T9521 arg1Of impairs,that
R7976 T9425 T9424 arg2Of turn,in
R7977 T9534 T9531 arg2Of activation,impairs
R7978 T9534 T9532 arg1Of activation,antigen-receptor
R7979 T9534 T9533 arg1Of activation,dependent
R798 T916 T917 arg1Of levels,","
R7980 T9534 T9535 arg1Of activation,of
R7981 T9536 T9535 arg2Of NF-κB,of
R7982 T9537 T9538 arg1Of They,showed
R7983 T9427 T9424 arg1Of regulated,in
R7984 T9541 T9540 arg1Of activation,NF-κB
R7985 T9541 T9542 arg1Of activation,via
R7986 T9541 T9544 arg1Of activation,requires
R7987 T9541 T9547 arg1Of activation,acts
R7988 T9427 T9426 arg2Of regulated,is
R7989 T9429 T9427 arg1Of PKC,regulated
R799 T916 T919 arg1Of levels,as
R7990 T9543 T9542 arg2Of Akt,via
R7991 T9544 T9546 arg1Of requires,and
R7992 T9545 T9544 arg2Of CARMA1,requires
R7993 T9546 T9538 arg2Of and,showed
R7994 T9546 T9539 arg1Of and,that
R7995 T9429 T9428 arg2Of PKC,by
R7996 T9547 T9546 arg2Of acts,and
R7997 T9547 T9548 arg1Of acts,in
R7998 T9431 T9430 arg1Of studies,Recent
R7999 T9549 T9548 arg2Of cooperation,in
R800 T919 T918 arg1Of as,such
R8000 T9549 T9550 arg1Of cooperation,with
R8001 T9551 T9550 arg2Of PKC,with
R8002 T9551 T9552 arg1Of PKC,following
R8003 T9431 T9432 arg1Of studies,have
R8004 T9554 T9552 arg2Of exposure,following
R8005 T9554 T9553 arg1Of exposure,short-term
R8006 T9554 T9555 arg1Of exposure,(
R8007 T9554 T9559 arg1Of exposure,of
R8008 T9554 T9562 arg1Of exposure,with
R8009 T9431 T9433 arg1Of studies,established
R801 T920 T921 arg1Of AIDS,and
R8010 T9433 T9432 arg2Of established,have
R8011 T9557 T9555 arg2Of min,(
R8012 T9557 T9556 arg1Of min,30
R8013 T9558 T9555 arg3Of ),(
R8014 T9435 T9433 arg2Of importance,established
R8015 T9561 T9559 arg2Of T-cells,of
R8016 T9561 T9560 arg1Of T-cells,Jurkat
R8017 T9563 T9562 arg2Of PMA,with
R8018 T9564 T9565 arg1Of Akt,phosphorylates
R8019 T9564 T9568 arg1Of Akt,activates
R802 T921 T919 arg2Of and,as
R8020 T9435 T9434 arg1Of importance,the
R8021 T9565 T9566 arg1Of phosphorylates,and
R8022 T9435 T9436 arg1Of importance,of
R8023 T9435 T9440 arg1Of importance,consisting
R8024 T9568 T9566 arg2Of activates,and
R8025 T9568 T9567 arg1Of activates,thus
R8026 T9569 T9568 arg2Of Bcl10,activates
R8027 T9439 T9436 arg2Of complex,of
R8028 T9571 T9570 arg1Of studies,These
R8029 T9571 T9572 arg1Of studies,indicate
R803 T923 T921 arg2Of diseases,and
R8030 T9574 T9575 arg1Of PKC,is
R8031 T9574 T9576 arg1Of PKC,crucial
R8032 T9575 T9573 arg1Of is,that
R8033 T9575 T9587 arg1Of is,bound
R8034 T9576 T9575 arg2Of crucial,is
R8035 T9576 T9577 arg1Of crucial,for
R8036 T9439 T9437 arg1Of complex,a
R8037 T9579 T9577 arg2Of activation,for
R8038 T9579 T9578 arg1Of activation,NF-κB
R8039 T9579 T9580 arg1Of activation,following
R804 T923 T922 arg1Of diseases,autoimmune
R8040 T9580 T9583 arg1Of following,through
R8041 T9439 T9438 arg1Of complex,protein
R8042 T9440 T9441 arg1Of consisting,of
R8043 T9442 T9443 arg1Of CARMA1,","
R8044 T9443 T9445 arg1Of ",",and
R8045 T9444 T9443 arg2Of Bcl10,","
R8046 T9582 T9580 arg2Of treatment,following
R8047 T9582 T9581 arg1Of treatment,short-term
R8048 T9584 T9583 arg2Of signals,through
R8049 T9584 T9585 arg1Of signals,via
R8050 T9445 T9441 arg2Of and,of
R8051 T9586 T9585 arg2Of membrane,via
R8052 T9587 T9572 arg2Of bound,indicate
R8053 T9445 T9450 arg1Of and,","
R8054 T9588 T9587 arg2Of receptors,bound
R8055 T9588 T9590 arg1Of receptors,as
R8056 T9445 T9451 arg1Of and,in
R8057 T9590 T9589 arg1Of as,such
R8058 T9446 T9445 arg2Of MALT1,and
R8059 T9592 T9591 arg1Of TCR,the
R8060 T9592 T9593 arg1Of TCR,and
R8061 T9593 T9590 arg2Of and,as
R8062 T9446 T9447 arg1Of MALT1,(
R8063 T9448 T9447 arg2Of CBM,(
R8064 T9597 T9593 arg2Of CD28,and
R8065 T9597 T9594 arg1Of CD28,the
R8066 T9597 T9595 arg1Of CD28,co-stimulatory
R8067 T9597 T9596 arg1Of CD28,receptor
R8068 T9449 T9447 arg3Of ),(
R8069 T9453 T9451 arg2Of induction,in
R8070 T9603 T9600 arg1Of proteins,the
R8071 T9603 T9601 arg1Of proteins,CBM
R8072 T9603 T9602 arg1Of proteins,complex
R8073 T9603 T9604 arg1Of proteins,play
R8074 T9604 T9598 arg1Of play,Thus
R8075 T9604 T9599 arg1Of play,","
R8076 T9604 T9608 arg1Of play,in
R8077 T9607 T9604 arg2Of role,play
R8078 T9607 T9605 arg1Of role,a
R8079 T9607 T9606 arg1Of role,key
R8080 T9611 T9608 arg2Of process,in
R8081 T9611 T9609 arg1Of process,this
R8082 T9611 T9610 arg1Of process,signalling
R8083 T9612 T9613 arg1Of PMA,diffuses
R8084 T9453 T9452 arg1Of induction,the
R8085 T9612 T9619 arg1Of PMA,activates
R8086 T9453 T9454 arg1Of induction,of
R8087 T9613 T9614 arg1Of diffuses,into
R8088 T9613 T9617 arg1Of diffuses,and
R8089 T9455 T9454 arg2Of NF-κB,of
R8090 T9616 T9614 arg2Of cytosol,into
R8091 T9616 T9615 arg1Of cytosol,the
R8092 T9457 T9458 arg1Of Bcl10,","
R8093 T9619 T9617 arg2Of activates,and
R8094 T9619 T9618 arg1Of activates,directly
R8095 T9619 T9621 arg1Of activates,since
R8096 T9620 T9619 arg2Of PKC,activates
R8097 T9458 T9460 arg1Of ",",and
R8098 T9622 T9623 arg1Of it,is
R8099 T9623 T9621 arg2Of is,since
R8100 T9459 T9458 arg2Of Scharschmidt,","
R8101 T9625 T9623 arg2Of analogue,is
R8102 T9625 T9624 arg1Of analogue,an
R8103 T9625 T9626 arg1Of analogue,to
R8104 T9460 T9456 arg1Of and,Investigating
R8105 T9627 T9626 arg2Of diacylglycerol,to
R8106 T9627 T9628 arg1Of diacylglycerol,[
R8107 T9629 T9628 arg2Of 48,[
R8108 T9460 T9462 arg1Of and,[
R8109 T9630 T9628 arg3Of ],[
R8110 T9460 T9465 arg1Of and,demonstrated
R8111 T9632 T9631 arg1Of studies,Several
R8112 T9632 T9633 arg1Of studies,have
R8113 T9632 T9634 arg1Of studies,demonstrated
R8114 T9461 T9460 arg2Of colleagues,and
R8115 T9634 T9633 arg2Of demonstrated,have
R8116 T9463 T9462 arg2Of 47,[
R8117 T9636 T9637 arg1Of inhibition,of
R8118 T9636 T9639 arg1Of inhibition,blocks
R8119 T9636 T9645 arg1Of inhibition,suggesting
R8120 T9638 T9637 arg2Of PKC,of
R8121 T9639 T9634 arg2Of blocks,demonstrated
R8122 T9639 T9635 arg1Of blocks,that
R8123 T9639 T9644 arg1Of blocks,","
R8124 T9639 T9655 arg1Of blocks,[
R8125 T9640 T9641 arg1Of NF-κB,and
R8126 T9464 T9462 arg3Of ],[
R8127 T9642 T9641 arg2Of AP-1,and
R8128 T9643 T9639 arg2Of activity,blocks
R8129 T9643 T9640 arg1Of activity,NF-κB
R8130 T9643 T9642 arg1Of activity,AP-1
R8131 T9645 T9639 arg3Of suggesting,blocks
R8132 T9645 T9653 arg1Of suggesting,by
R8133 T9648 T9645 arg2Of regulation,suggesting
R8134 T9648 T9646 arg1Of regulation,a
R8135 T9648 T9647 arg1Of regulation,direct
R8136 T9648 T9649 arg1Of regulation,of
R8137 T9467 T9468 arg1Of it,is
R8138 T9652 T9649 arg2Of factors,of
R8139 T9652 T9650 arg1Of factors,these
R8140 T9652 T9651 arg1Of factors,transcription
R8141 T9654 T9653 arg2Of PKC,by
R8142 T9468 T9465 arg2Of is,demonstrated
R8143 T9656 T9655 arg2Of "49,50",[
R8144 T9657 T9655 arg3Of ],[
R8145 T9658 T9659 arg1Of PKC,is
R8146 T9658 T9660 arg2Of PKC,activated
R8147 T9658 T9669 arg1Of PKC,is
R8148 T9468 T9466 arg1Of is,that
R8149 T9660 T9659 arg2Of activated,is
R8150 T9660 T9661 arg1Of activated,at
R8151 T9660 T9665 arg1Of activated,following
R8152 T9660 T9668 arg1Of activated,and
R8153 T9471 T9468 arg2Of regulator,is
R8154 T9664 T9661 arg2Of stage,at
R8155 T9664 T9662 arg1Of stage,an
R8156 T9664 T9663 arg1Of stage,early
R8157 T9471 T9469 arg1Of regulator,a
R8158 T9667 T9665 arg2Of stimulation,following
R8159 T9667 T9666 arg1Of stimulation,T-cell
R8160 T9471 T9470 arg1Of regulator,critical
R8161 T9669 T9668 arg2Of is,and
R8162 T9669 T9670 arg1Of is,therefore
R8163 T9471 T9472 arg1Of regulator,of
R8164 T9474 T9472 arg2Of activity,of
R8165 T9673 T9669 arg2Of regulator,is
R8166 T9673 T9671 arg1Of regulator,an
R8167 T9673 T9672 arg1Of regulator,important
R8168 T9673 T9674 arg1Of regulator,of
R8169 T9474 T9473 arg1Of activity,NF-κB
R8170 T9475 T9476 arg1Of Down-regulation,of
R8171 T9475 T9478 arg1Of Down-regulation,from
R8172 T9475 T9486 arg1Of Down-regulation,resulted
R8173 T9477 T9476 arg2Of Bcl10,of
R8174 T9678 T9674 arg2Of pathways,of
R8175 T9678 T9675 arg1Of pathways,downstream
R8176 T9678 T9676 arg1Of pathways,inflammatory
R8177 T9678 T9677 arg1Of pathways,signalling
R8178 T9678 T9679 arg1Of pathways,leading
R8179 T9679 T9680 arg1Of leading,to
R8180 T9679 T9683 arg1Of leading,[
R8181 T9479 T9478 arg2Of signals,from
R8182 T9682 T9680 arg2Of expression,to
R8183 T9682 T9681 arg1Of expression,cytokine
R8184 T9684 T9683 arg2Of 50,[
R8185 T9685 T9683 arg3Of ],[
R8186 T9686 T9687 arg1Of We,have
R8187 T9479 T9480 arg2Of signals,transduced
R8188 T9686 T9688 arg1Of We,shown
R8189 T9480 T9481 arg1Of transduced,via
R8190 T9688 T9687 arg2Of shown,have
R8191 T9483 T9484 arg1Of TCR/CD28,and
R8192 T9690 T9691 arg1Of phosphorylated-PKC,is
R8193 T9690 T9693 arg2Of phosphorylated-PKC,regulated
R8194 T9693 T9688 arg2Of regulated,shown
R8195 T9693 T9689 arg1Of regulated,that
R8196 T9693 T9691 arg2Of regulated,is
R8197 T9693 T9692 arg1Of regulated,up
R8198 T9693 T9694 arg1Of regulated,in
R8199 T9693 T9702 arg1Of regulated,","
R8200 T9693 T9703 modOf regulated,indicating
R8201 T9778 T9776 arg1Of activation,prolonged
R8202 T9695 T9694 arg2Of response,in
R8203 T9695 T9696 arg1Of response,to
R8204 T9697 T9698 arg1Of PMA,and
R8205 T9698 T9696 arg2Of and,to
R8206 T9699 T9698 arg2Of HK,and
R8207 T9701 T9694 arg3Of coli,in
R8208 T9701 T9700 arg1Of coli,E.
R8209 T9778 T9777 arg1Of activation,PKC
R8210 T9778 T9779 arg1Of activation,by
R8211 T9778 T9781 arg1Of activation,leads
R8212 T9780 T9779 arg2Of PMA,by
R8213 T9705 T9703 arg2Of association,indicating
R8214 T9705 T9704 arg1Of association,an
R8215 T9705 T9706 arg1Of association,between
R8216 T9781 T9774 arg2Of leads,demonstrating
R8217 T9707 T9708 arg1Of PKC,and
R8218 T9781 T9775 arg1Of leads,that
R8219 T9708 T9706 arg2Of and,between
R8220 T9781 T9782 arg1Of leads,to
R8221 T9784 T9782 arg2Of inhibition,to
R8222 T9711 T9709 arg1Of factors,the
R8223 T9711 T9710 arg1Of factors,transcription
R8224 T9712 T9713 arg1Of AP-1,and
R8225 T9713 T9708 arg2Of and,and
R8226 T9713 T9711 arg1Of and,factors
R8227 T9714 T9713 arg2Of NF-κB,and
R8228 T9716 T9715 arg1Of levels,Bcl10
R8229 T9716 T9717 arg1Of levels,were
R8230 T9716 T9718 arg2Of levels,down-regulated
R8231 T9784 T9783 arg1Of inhibition,an
R8232 T9718 T9717 arg2Of down-regulated,were
R8233 T9718 T9719 arg1Of down-regulated,following
R8234 T9721 T9719 arg2Of treatment,following
R8235 T9721 T9720 arg2Of treatment,extended
R8236 T9721 T9722 arg1Of treatment,of
R8237 T9721 T9725 arg1Of treatment,with
R8238 T9784 T9785 arg1Of inhibition,of
R8239 T9724 T9722 arg2Of T-cells,of
R8240 T9724 T9723 arg1Of T-cells,Jurkat
R8241 T9786 T9787 arg1Of Bcl10,and
R8242 T9726 T9725 arg2Of PMA,with
R8243 T9787 T9785 arg2Of and,of
R8244 T9730 T9727 arg2Of groups,In
R8245 T9730 T9728 arg1Of groups,the
R8246 T9730 T9729 arg1Of groups,control
R8247 T9788 T9787 arg2Of NF-κB,and
R8248 T9733 T9732 arg1Of loss,a
R8249 T9733 T9734 arg1Of loss,of
R8250 T9733 T9736 arg1Of loss,occurred
R8251 T9735 T9734 arg2Of Bcl10,of
R8252 T9789 T9790 arg1Of It,has
R8253 T9736 T9727 arg1Of occurred,In
R8254 T9736 T9731 arg1Of occurred,","
R8255 T9736 T9737 arg1Of occurred,after
R8256 T9736 T9740 arg1Of occurred,","
R8257 T9736 T9741 modOf occurred,followed
R8258 T9736 T9748 arg1Of occurred,","
R8259 T9736 T9749 arg1Of occurred,which
R8260 T9736 T9750 arg1Of occurred,is
R8261 T9736 T9751 arg1Of occurred,in
R8262 T9739 T9737 arg2Of h,after
R8263 T9739 T9738 arg1Of h,6
R8264 T9789 T9791 arg1Of It,been
R8265 T9789 T9792 arg2Of It,shown
R8266 T9792 T9790 arg2Of shown,has
R8267 T9744 T9741 arg1Of increase,followed
R8268 T9744 T9742 arg2Of increase,by
R8269 T9744 T9743 arg1Of increase,an
R8270 T9744 T9745 arg1Of increase,after
R8271 T9747 T9745 arg2Of h,after
R8272 T9747 T9746 arg1Of h,24
R8273 T9792 T9791 arg2Of shown,been
R8274 T9794 T9795 arg1Of NF-κB,is
R8275 T9751 T9750 arg2Of in,is
R8276 T9752 T9751 arg2Of accordance,in
R8277 T9752 T9753 arg1Of accordance,with
R8278 T9795 T9792 arg3Of is,shown
R8279 T9795 T9793 arg1Of is,that
R8280 T9757 T9753 arg2Of activity,with
R8281 T9757 T9754 arg1Of activity,the
R8282 T9757 T9755 arg2Of activity,observed
R8283 T9757 T9756 arg1Of activity,NF-κB
R8284 T9757 T9758 arg1Of activity,(
R8285 T9759 T9758 arg2Of figure,(
R8286 T9800 T9795 arg2Of complex,is
R8287 T9759 T9760 arg1Of figure,7
R8288 T9761 T9758 arg3Of ),(
R8289 T9763 T9762 arg1Of results,These
R8290 T9763 T9764 arg1Of results,are
R8291 T9763 T9765 arg2Of results,supported
R8292 T9765 T9764 arg2Of supported,are
R8293 T9765 T9773 arg1Of supported,","
R8294 T9765 T9774 modOf supported,demonstrating
R8295 T9800 T9796 arg1Of complex,an
R8296 T9800 T9797 arg1Of complex,important
R8297 T9769 T9765 arg1Of study,supported
R8298 T9769 T9766 arg2Of study,by
R8299 T9769 T9767 arg1Of study,an
R8300 T9769 T9768 arg1Of study,earlier
R8301 T9769 T9770 arg1Of study,[
R8302 T9800 T9798 arg1Of complex,transcription
R8303 T9771 T9770 arg2Of 47,[
R8304 T9800 T9799 arg1Of complex,factor
R8305 T9772 T9770 arg3Of ],[
R8306 T9800 T9801 arg2Of complex,involved
R8307 T9801 T9802 arg1Of involved,in
R8308 T9804 T9803 arg1Of every,almost
R8309 T9805 T9802 arg2Of aspect,in
R8310 T9872 T9871 arg2Of secretion,following
R8311 T9872 T9873 arg1Of secretion,of
R8312 T9805 T9804 arg1Of aspect,every
R8313 T9805 T9806 arg1Of aspect,of
R8314 T9875 T9873 arg2Of cytokines,of
R8315 T9875 T9874 arg1Of cytokines,pro-inflammatory
R8316 T9808 T9806 arg2Of regulation,of
R8317 T9879 T9876 arg2Of persons,In
R8318 T9879 T9877 arg1Of persons,HIV
R8319 T9879 T9878 arg1Of persons,infected
R8320 T9808 T9807 arg1Of regulation,cell
R8321 T9808 T9809 arg1Of regulation,including
R8322 T9883 T9881 arg1Of levels,serum
R8323 T9883 T9882 arg1Of levels,CXCL8
R8324 T9883 T9884 arg1Of levels,are
R8325 T9883 T9885 arg2Of levels,elevated
R8326 T9810 T9811 arg1Of apoptosis,","
R8327 T9885 T9884 arg2Of elevated,are
R8328 T9885 T9886 arg1Of elevated,and
R8329 T9886 T9876 arg1Of and,In
R8330 T9886 T9880 arg1Of and,","
R8331 T9887 T9888 arg1Of this,could
R8332 T9887 T9889 arg1Of this,recruit
R8333 T9889 T9886 arg2Of recruit,and
R8334 T9889 T9888 arg2Of recruit,could
R8335 T9889 T9902 arg1Of recruit,since
R8336 T9891 T9889 arg2Of T-cells,recruit
R8337 T9891 T9890 arg1Of T-cells,more
R8338 T9811 T9813 arg1Of ",",","
R8339 T9891 T9893 arg1Of T-cells,leading
R8340 T9812 T9811 arg2Of differentiation,","
R8341 T9813 T9815 arg1Of ",",and
R8342 T9893 T9892 arg1Of leading,potentially
R8343 T9893 T9894 arg1Of leading,to
R8344 T9814 T9813 arg2Of proliferation,","
R8345 T9897 T9896 arg1Of rapid,more
R8346 T9898 T9894 arg2Of progression,to
R8347 T9898 T9895 arg1Of progression,a
R8348 T9898 T9897 arg1Of progression,rapid
R8349 T9898 T9899 arg1Of progression,of
R8350 T9815 T9809 arg2Of and,including
R8351 T9901 T9899 arg2Of disease,of
R8352 T9901 T9900 arg1Of disease,the
R8353 T9815 T9817 arg1Of and,of
R8354 T9903 T9904 arg1Of there,will
R8355 T9903 T9905 arg1Of there,be
R8356 T9815 T9820 arg1Of and,[
R8357 T9905 T9902 arg2Of be,since
R8358 T9905 T9904 arg2Of be,will
R8359 T9816 T9815 arg2Of initiation,and
R8360 T9907 T9905 arg2Of T-cells,be
R8361 T9907 T9906 arg1Of T-cells,more
R8362 T9819 T9817 arg2Of responses,of
R8363 T9907 T9908 arg1Of T-cells,available
R8364 T9819 T9818 arg1Of responses,immune
R8365 T9910 T9908 arg2Of infect,available
R8366 T9910 T9909 arg1Of infect,to
R8367 T9821 T9820 arg2Of 51-53,[
R8368 T9822 T9820 arg3Of ],[
R8369 T9823 T9824 arg1Of NF-κB,is
R8370 T9823 T9826 arg1Of NF-κB,active
R8371 T9826 T9824 arg2Of active,is
R8372 T9826 T9825 arg1Of active,constitutively
R8373 T9826 T9827 arg1Of active,in
R8374 T9830 T9827 arg2Of malignancies,in
R8377 T9830 T9828 arg1Of malignancies,many
R8381 T9830 T9829 arg1Of malignancies,human
R8382 T9830 T9831 arg1Of malignancies,","
R8383 T9830 T9832 arg1Of malignancies,which
R8384 T9830 T9833 arg1Of malignancies,makes
R8385 T9833 T9839 arg1Of makes,[
R8386 T9834 T9833 arg2Of it,makes
R8387 T9838 T9833 arg3Of target,makes
R8388 T9838 T9835 arg1Of target,an
R8389 T9838 T9836 arg1Of target,attractive
R8390 T9838 T9837 arg1Of target,therapeutic
R8391 T9840 T9839 arg2Of 54,[
R8392 T9841 T9839 arg3Of ],[
R8393 T9844 T9842 arg1Of levels,Elevated
R8394 T9844 T9843 arg1Of levels,CXCL8
R8395 T9844 T9845 arg1Of levels,during
R8396 T9844 T9848 arg1Of levels,result
R8397 T9847 T9845 arg2Of inflammation,during
R8398 T9847 T9846 arg1Of inflammation,chronic
R8399 T9848 T9849 arg1Of result,in
R8400 T9852 T9849 arg2Of recruitment,in
R8401 T9852 T9850 arg1Of recruitment,an
R8402 T9852 T9851 arg2Of recruitment,enhanced
R8403 T9852 T9853 arg1Of recruitment,of
R8404 T9852 T9856 arg1Of recruitment,to
R8405 T9855 T9853 arg2Of cells,of
R8406 T9855 T9854 arg1Of cells,immune
R8407 T9858 T9856 arg2Of site,to
R8408 T9858 T9857 arg1Of site,the
R8409 T9858 T9859 arg1Of site,of
R8410 T9858 T9861 arg1Of site,","
R8411 T9858 T9862 arg1Of site,which
R8412 T9858 T9863 arg1Of site,may
R8413 T9858 T9864 arg1Of site,lead
R8414 T9860 T9859 arg2Of infection,of
R8415 T9864 T9863 arg2Of lead,may
R8416 T9864 T9865 arg1Of lead,to
R8417 T9867 T9865 arg2Of development,to
R8418 T9867 T9866 arg1Of development,the
R8419 T9867 T9868 arg1Of development,of
R8420 T9870 T9868 arg2Of diseases,of
R8421 T9870 T9869 arg1Of diseases,autoimmune
R8422 T9870 T9871 arg1Of diseases,following
R9254 T11620 T11617 arg2Of study,In
R9255 T11620 T11618 arg1Of study,the
R9256 T11620 T11619 arg1Of study,present
R9257 T11623 T11622 arg1Of release,IL-6
R9258 T11623 T11624 arg1Of release,was
R9259 T11623 T11625 arg2Of release,found
R9260 T11623 T11627 arg1Of release,be
R9261 T11623 T11628 arg2Of release,associated
R9262 T11625 T11617 arg1Of found,In
R9263 T11625 T11621 arg1Of found,","
R9264 T11625 T11624 arg2Of found,was
R9265 T11625 T11632 arg1Of found,while
R9266 T11628 T11625 arg3Of associated,found
R9267 T11628 T11626 arg1Of associated,to
R9268 T11628 T11627 arg2Of associated,be
R9269 T11628 T11629 arg1Of associated,with
R9270 T11631 T11629 arg2Of activity,with
R9271 T11631 T11630 arg1Of activity,NF-κB
R9272 T11634 T11633 arg1Of release,CXCL8
R9273 T11634 T11637 arg1Of release,correlated
R9274 T11636 T11635 arg1Of closely,more
R9275 T11637 T11632 arg2Of correlated,while
R9276 T11637 T11636 arg1Of correlated,closely
R9277 T11637 T11638 arg1Of correlated,with
R9278 T11640 T11638 arg2Of activity,with
R9279 T11640 T11639 arg1Of activity,AP-1
R9280 T11641 T11642 arg1Of Treatment,of
R9281 T11641 T11645 arg1Of Treatment,with
R9282 T11641 T11647 arg1Of Treatment,was
R9283 T11641 T11649 arg1Of Treatment,potent
R9284 T11644 T11642 arg2Of T-cells,of
R9285 T11644 T11643 arg1Of T-cells,Jurkat
R9286 T11646 T11645 arg2Of PMA,with
R9287 T11649 T11647 arg2Of potent,was
R9288 T11649 T11648 arg1Of potent,more
R9289 T11649 T11650 arg1Of potent,than
R9290 T11649 T11654 arg1Of potent,at
R9291 T11653 T11650 arg2Of coli,than
R9292 T11653 T11651 arg1Of coli,HK
R9293 T11653 T11652 arg1Of coli,E.
R9294 T11655 T11654 arg2Of elevating,at
R9295 T11658 T11655 arg2Of levels,elevating
R9296 T11658 T11656 arg1Of levels,the
R9297 T11658 T11657 arg1Of levels,CXCL8
R9298 T11659 T11660 arg1Of PMA,induced
R9299 T11660 T11666 arg1Of induced,while
R9300 T11662 T11661 arg1Of activation,AP-1
R9301 T11662 T11663 arg1Of activation,and
R9302 T11663 T11660 arg2Of and,induced
R9303 T11665 T11663 arg2Of NF-κB,and
R9304 T11665 T11664 arg2Of NF-κB,down-regulated
R9305 T11667 T11669 arg1Of HK,coli
R9306 T11667 T11670 arg1Of HK,up-regulated
R9307 T11667 T11673 arg1Of HK,affecting
R9308 T11669 T11668 arg1Of coli,E.
R9309 T11670 T11666 arg2Of up-regulated,while
R9310 T11670 T11672 arg1Of up-regulated,without
R9311 T11671 T11670 arg2Of NF-κB,up-regulated
R9312 T11673 T11672 arg2Of affecting,without
R9313 T11675 T11673 arg2Of activity,affecting
R9314 T11675 T11674 arg1Of activity,AP-1
R9315 T11677 T11676 arg2Of addition,In
R9316 T11682 T11679 arg1Of pattern,the
R9317 T11682 T11680 arg1Of pattern,temporal
R9318 T11682 T11681 arg1Of pattern,induction
R9319 T11682 T11683 arg1Of pattern,of
R9320 T11682 T11685 arg1Of pattern,correlated
R9321 T11684 T11683 arg2Of AP-1,of
R9322 T11685 T11676 arg1Of correlated,In
R9323 T11685 T11678 arg1Of correlated,","
R9324 T11685 T11686 arg1Of correlated,to
R9325 T11685 T11691 arg1Of correlated,while
R9326 T11688 T11686 arg2Of release,to
R9327 T11688 T11687 arg1Of release,the
R9328 T11688 T11689 arg1Of release,of
R9329 T11690 T11689 arg2Of CXCL8,of
R9330 T11692 T11693 arg1Of IL-6,followed
R9331 T11693 T11691 arg2Of followed,while
R9332 T11696 T11693 arg2Of activity,followed
R9333 T11696 T11694 arg1Of activity,the
R9334 T11696 T11695 arg1Of activity,NF-κB
R9335 T11701 T11699 arg1Of activation,blocking
R9336 T11701 T11700 arg1Of activation,NF-κB
R9337 T11701 T11702 arg1Of activation,resulted
R9338 T11702 T11697 arg1Of resulted,Likewise
R9339 T11702 T11698 arg1Of resulted,","
R9340 T11702 T11703 arg1Of resulted,in
R9341 T11702 T11709 arg1Of resulted,while
R9342 T11706 T11703 arg2Of inhibition,in
R9343 T11706 T11704 arg1Of inhibition,a
R9344 T11706 T11705 arg1Of inhibition,complete
R9345 T11706 T11707 arg1Of inhibition,of
R9346 T11708 T11707 arg2Of IL-6,of
R9347 T11712 T11710 arg1Of levels,the
R9348 T11712 T11711 arg1Of levels,CXCL8
R9349 T11712 T11713 arg1Of levels,remained
R9350 T11712 T11714 arg1Of levels,elevated
R9351 T11713 T11709 arg2Of remained,while
R9352 T11713 T11715 arg1Of remained,as
R9353 T11714 T11713 arg2Of elevated,remained
R9354 T11716 T11715 arg2Of shown,as
R9355 T11716 T11718 arg1Of shown,at
R9356 T11718 T11717 arg1Of at,both
R9357 T11720 T11721 arg1Of protein,and
R9358 T11722 T11721 arg2Of mRNA,and
R9359 T11723 T11718 arg2Of level,at
R9360 T11723 T11719 arg1Of level,the
R9361 T11723 T11720 arg1Of level,protein
R9362 T11723 T11722 arg1Of level,mRNA
R9363 T11728 T11726 arg1Of release,the
R9364 T11728 T11727 arg1Of release,CXCL8
R9365 T11728 T11729 arg1Of release,was
R9366 T11728 T11730 arg2Of release,down-regulated
R9367 T11730 T11724 arg1Of down-regulated,Furthermore
R9368 T11730 T11725 arg1Of down-regulated,","
R9369 T11730 T11729 arg2Of down-regulated,was
R9370 T11732 T11730 arg1Of inhibition,down-regulated
R9371 T11732 T11731 arg2Of inhibition,by
R9372 T11732 T11733 arg1Of inhibition,of
R9373 T11735 T11733 arg2Of activity,of
R9374 T11735 T11734 arg1Of activity,JNK
R9375 T11738 T11736 arg1Of study,The
R9376 T11738 T11737 arg1Of study,present
R9377 T11738 T11739 arg1Of study,indicates
R9378 T11743 T11741 arg2Of T-cells,in
R9379 T11743 T11742 arg1Of T-cells,Jurkat
R9380 T11745 T11746 arg1Of IL-6,is
R9381 T11745 T11747 arg2Of IL-6,regulated
R9382 T11745 T11759 arg2Of IL-6,associated
R9383 T11747 T11748 arg1Of regulated,through
R9384 T11747 T11750 arg1Of regulated,while
R9385 T11747 T11757 arg1Of regulated,and
R9386 T11749 T11748 arg2Of NF-κB,through
R9387 T11752 T11751 arg1Of regulation,CXCL8
R9388 T11752 T11753 arg1Of regulation,is
R9389 T11752 T11754 arg1Of regulation,independent
R9390 T11753 T11750 arg2Of is,while
R9391 T11754 T11753 arg2Of independent,is
R9392 T11754 T11755 arg1Of independent,of
R9393 T11756 T11755 arg2Of NF-κB,of
R9394 T11757 T11739 arg2Of and,indicates
R9395 T11757 T11740 arg1Of and,that
R9396 T11757 T11741 arg1Of and,in
R9397 T11757 T11744 arg1Of and,","
R9398 T11757 T11746 arg2Of and,is
R9399 T11759 T11757 arg2Of associated,and
R9400 T11759 T11758 arg1Of associated,closely
R9401 T11759 T11760 arg1Of associated,with
R9402 T11762 T11760 arg2Of activation,with
R9403 T11762 T11761 arg1Of activation,AP-1
R9600 T12075 T12073 arg1Of chemicals,The
R9601 T12075 T12074 arg1Of chemicals,following
R9602 T12075 T12076 arg1Of chemicals,were
R9603 T12075 T12077 arg2Of chemicals,used
R9604 T12077 T12076 arg2Of used,were
R9605 T12077 T12078 arg1Of used,in
R9606 T12077 T12082 arg1Of used,:
R9607 T12077 T12083 arg1Of used,PMA
R9608 T12081 T12078 arg2Of study,in
R9609 T12081 T12079 arg1Of study,the
R9610 T12081 T12080 arg1Of study,present
R9611 T12083 T12084 arg1Of PMA,(
R9612 T12083 T12097 arg1Of PMA,;
R9613 T12087 T12084 arg2Of 13-acetate,(
R9614 T12087 T12085 arg1Of 13-acetate,Phorbol
R9615 T12087 T12086 arg1Of 13-acetate,12-myristate
R9616 T12087 T12088 arg1Of 13-acetate,","
R9617 T12087 T12089 arg1Of 13-acetate,(
R9618 T12092 T12089 arg2Of P1585,(
R9619 T12092 T12090 arg1Of P1585,Sigma
R9620 T12092 T12091 arg1Of P1585,#
R9621 T12092 T12093 arg1Of P1585,","
R9622 T12092 T12094 arg1Of P1585,USA
R9623 T12095 T12089 arg3Of ),(
R9624 T12096 T12084 arg3Of ),(
R9625 T12100 T12098 arg1Of inhibitor,NF-κB
R9626 T12100 T12099 arg1Of inhibitor,activation
R9627 T12100 T12101 arg1Of inhibitor,(
R9628 T12100 T12104 arg1Of inhibitor,","
R9629 T12100 T12105 arg1Of inhibitor,(
R9630 T12100 T12117 arg1Of inhibitor,;
R9631 T12102 T12101 arg2Of NAI,(
R9632 T12103 T12101 arg3Of ),(
R9633 T12109 T12105 arg2Of Inhibitor,(
R9634 T12109 T12106 arg1Of Inhibitor,InSolution™
R9635 T12109 T12107 arg1Of Inhibitor,NF-κB
R9636 T12109 T12108 arg1Of Inhibitor,Activation
R9637 T12109 T12110 arg1Of Inhibitor,","
R9638 T12109 T12114 arg1Of Inhibitor,","
R9639 T12113 T12110 arg2Of 481407,","
R9640 T12113 T12111 arg1Of 481407,Calbiochem
R9641 T12113 T12112 arg1Of 481407,#
R9642 T12115 T12114 arg2Of USA,","
R9643 T12116 T12105 arg3Of ),(
R9644 T12117 T12120 arg1Of ;,","
R9645 T12117 T12121 arg1Of ;,(
R9646 T12117 T12133 arg1Of ;,;
R9647 T12119 T12117 arg2Of inhibitor,;
R9648 T12119 T12118 arg1Of inhibitor,JNK
R9649 T12123 T12122 arg1Of JNK,InSolution™
R9650 T12124 T12121 arg2Of Inhibitor,(
R9651 T12124 T12123 arg1Of Inhibitor,JNK
R9652 T12124 T12125 arg1Of Inhibitor,II
R9653 T12124 T12126 arg1Of Inhibitor,","
R9654 T12124 T12130 arg1Of Inhibitor,","
R9655 T12129 T12126 arg2Of 420128,","
R9656 T12129 T12127 arg1Of 420128,Calbiochem
R9657 T12129 T12128 arg1Of 420128,#
R9658 T12131 T12130 arg2Of USA,","
R9659 T12132 T12121 arg3Of ),(
R9660 T12133 T12136 arg1Of ;,","
R9661 T12133 T12137 arg1Of ;,(
R9662 T12133 T12148 arg1Of ;,;
R9663 T12135 T12133 arg2Of Inhibitor,;
R9664 T12135 T12134 arg1Of Inhibitor,PKC
R9665 T12140 T12138 arg1Of I,InSolution™
R9666 T12140 T12139 arg1Of I,Bisindolylmaleimide
R9667 T12140 T12141 arg1Of I,","
R9668 T12142 T12141 arg2Of Calbiochem,","
R9669 T12144 T12137 arg2Of 203293,(
R9670 T12144 T12140 arg1Of 203293,I
R9671 T12144 T12142 arg1Of 203293,Calbiochem
R9672 T12144 T12143 arg1Of 203293,#
R9673 T12144 T12145 arg1Of 203293,","
R9674 T12146 T12145 arg2Of USA,","
R9675 T12147 T12137 arg3Of ),(
R9676 T12148 T12097 arg2Of ;,;
R9677 T12148 T12151 arg1Of ;,","
R9678 T12148 T12152 arg1Of ;,(
R9679 T12150 T12148 arg2Of Ionophore,;
R9680 T12150 T12149 arg1Of Ionophore,Calcium
R9681 T12154 T12153 arg1Of Ionophore,Calcium
R9682 T12159 T12152 arg2Of salt,(
R9683 T12159 T12154 arg1Of salt,Ionophore
R9684 T12159 T12155 arg1Of salt,A23187
R9685 T12159 T12156 arg1Of salt,mixed
R9686 T12159 T12157 arg1Of salt,calcium
R9687 T12159 T12158 arg1Of salt,magnesium
R9688 T12159 T12160 arg1Of salt,","
R9689 T12159 T12164 arg1Of salt,","
R9690 T12163 T12160 arg2Of C5149,","
R9691 T12163 T12161 arg1Of C5149,Sigma
R9692 T12163 T12162 arg1Of C5149,#
R9693 T12165 T12164 arg2Of USA,","
R9694 T12166 T12152 arg3Of ),(
R9836 T12332 T12333 arg1Of Heat,killed
R9837 T12333 T12334 arg1Of killed,(
R9838 T12335 T12334 arg2Of HK,(
R9839 T12336 T12334 arg3Of ),(
R9840 T12338 T12333 arg2Of coli,killed
R9841 T12338 T12337 arg1Of coli,Escherichia
R9842 T12341 T12339 arg1Of MG1655,E.
R9843 T12341 T12340 arg1Of MG1655,coli
R9844 T12341 T12342 arg1Of MG1655,were
R9845 T12341 T12343 arg2Of MG1655,grown
R9846 T12341 T12351 arg2Of MG1655,incubated
R9847 T12343 T12344 arg1Of grown,on
R9848 T12343 T12350 arg1Of grown,and
R9849 T12347 T12346 arg2Of LB,(
R9850 T12348 T12346 arg3Of ),(
R9851 T12349 T12344 arg2Of agar,on
R9852 T12349 T12345 arg1Of agar,Luria-Bertani
R9853 T12349 T12346 arg1Of agar,(
R9854 T12350 T12342 arg2Of and,were
R9855 T12351 T12350 arg2Of incubated,and
R9856 T12351 T12352 arg1Of incubated,at
R9857 T12351 T12354 arg1Of incubated,overnight
R9858 T12353 T12352 arg2Of 37°C,at
R9859 T12356 T12355 arg1Of colony,One
R9860 T12356 T12357 arg1Of colony,was
R9861 T12356 T12358 arg2Of colony,inoculated
R9862 T12356 T12365 arg2Of colony,incubated
R9863 T12358 T12359 arg1Of inoculated,into
R9864 T12358 T12364 arg1Of inoculated,and
R9865 T12363 T12359 arg2Of broth,into
R9866 T12363 T12360 arg1Of broth,10
R9867 T12363 T12361 arg1Of broth,ml
R9868 T12363 T12362 arg1Of broth,LB
R9869 T12364 T12357 arg2Of and,was
R9870 T12365 T12364 arg2Of incubated,and
R9871 T12365 T12366 arg1Of incubated,on
R9872 T12365 T12373 arg1Of incubated,at
R9873 T12365 T12375 arg1Of incubated,overnight
R9874 T12368 T12366 arg2Of shaker,on
R9875 T12368 T12367 arg1Of shaker,a
R9876 T12368 T12369 arg1Of shaker,(
R9877 T12371 T12369 arg2Of rpm,(
R9878 T12371 T12370 arg1Of rpm,200
R9879 T12372 T12369 arg3Of ),(
R9880 T12374 T12373 arg2Of 37°C,at
R9881 T12377 T12376 arg1Of bacteria,The
R9882 T12377 T12378 arg1Of bacteria,were
R9883 T12377 T12379 arg2Of bacteria,centrifuged
R9884 T12377 T12417 arg1Of bacteria,resuspended
R9885 T12379 T12378 arg2Of centrifuged,were
R9886 T12379 T12380 arg1Of centrifuged,for
R9887 T12379 T12416 arg1Of centrifuged,and
R9888 T12382 T12380 arg2Of min,for
R9889 T12382 T12381 arg1Of min,10
R9890 T12382 T12383 arg1Of min,at
R9891 T12382 T12387 arg1Of min,","
R9892 T12382 T12388 arg2Of min,washed
R9893 T12382 T12395 arg1Of min,(
R9894 T12386 T12383 arg2Of g,at
R9895 T12386 T12384 arg1Of g,3000
R9896 T12386 T12385 arg1Of g,×
R9897 T12388 T12389 arg1Of washed,with
R9898 T12394 T12389 arg2Of saline,with
R9899 T12394 T12390 arg1Of saline,3
R9900 T12394 T12391 arg1Of saline,ml
R9901 T12394 T12392 arg1Of saline,phosphate
R9902 T12394 T12393 arg2Of saline,buffered
R9903 T12396 T12395 arg2Of PBS,(
R9904 T12396 T12397 arg1Of PBS,;
R9905 T12396 T12413 arg1Of PBS,","
R9906 T12400 T12397 arg2Of NaCl,;
R9907 T12400 T12398 arg1Of NaCl,8
R9908 T12400 T12399 arg1Of NaCl,g
R9909 T12400 T12401 arg1Of NaCl,","
R9910 T12400 T12405 arg1Of NaCl,","
R9911 T12400 T12409 arg1Of NaCl,","
R9912 T12404 T12401 arg2Of Na2HPO4,","
R9913 T12404 T12402 arg1Of Na2HPO4,1.16
R9914 T12404 T12403 arg1Of Na2HPO4,g
R9915 T12408 T12405 arg2Of KH2PO4,","
R9916 T12408 T12406 arg1Of KH2PO4,0.2
R9917 T12408 T12407 arg1Of KH2PO4,g
R9918 T12412 T12409 arg2Of KCl,","
R9919 T12412 T12410 arg1Of KCl,0.2
R9920 T12412 T12411 arg1Of KCl,g
R9921 T12414 T12413 arg2Of pH7,","
R9922 T12415 T12395 arg3Of ),(
R9923 T12417 T12416 arg2Of resuspended,and
R9924 T12417 T12418 arg1Of resuspended,in
R9925 T12421 T12418 arg2Of PBS,in
R9926 T12421 T12419 arg1Of PBS,50
R9927 T12421 T12420 arg1Of PBS,μl
R9928 T12423 T12422 arg1Of bacteria,The
R9929 T12423 T12424 arg1Of bacteria,were
R9930 T12423 T12425 arg2Of bacteria,killed
R9931 T12425 T12424 arg2Of killed,were
R9932 T12425 T12426 arg1Of killed,by
R9933 T12427 T12426 arg2Of heating,by
R9934 T12427 T12428 arg1Of heating,to
R9935 T12427 T12430 arg1Of heating,for
R9936 T12429 T12428 arg2Of 70°C,to
R9937 T12432 T12430 arg2Of h,for
R9938 T12432 T12431 arg1Of h,1
R9939 T12434 T12433 arg1Of ensure,To
R9940 T12437 T12436 arg1Of bacteria,the
R9941 T12437 T12438 arg1Of bacteria,were
R9942 T12437 T12439 arg2Of bacteria,killed
R9943 T12439 T12434 arg2Of killed,ensure
R9944 T12439 T12435 arg1Of killed,that
R9945 T12439 T12438 arg2Of killed,were
R9946 T12439 T12440 arg1Of killed,;
R9947 T12442 T12441 arg1Of μl,10
R9948 T12442 T12443 arg1Of μl,of
R9949 T12442 T12447 arg1Of μl,was
R9950 T12442 T12448 arg2Of μl,spread
R9951 T12442 T12454 arg2Of μl,incubated
R9952 T12446 T12443 arg2Of suspension,of
R9953 T12446 T12444 arg1Of suspension,the
R9954 T12446 T12445 arg1Of suspension,heat-killed
R9955 T12448 T12449 arg1Of spread,on
R9956 T12448 T12453 arg1Of spread,and
R9957 T12452 T12449 arg2Of plate,on
R9958 T12452 T12450 arg1Of plate,a
R9959 T12452 T12451 arg1Of plate,LB
R9960 T12453 T12440 arg2Of and,;
R9961 T12453 T12447 arg2Of and,was
R9962 T12454 T12453 arg2Of incubated,and
R9963 T12454 T12455 arg1Of incubated,overnight
R9964 T12454 T12456 arg1Of incubated,at
R9965 T12457 T12456 arg2Of 37°C,at