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PMC:2817507 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T155 0-10 NN denotes Activation
T156 11-13 IN denotes of
T157 14-27 JJ denotes TLR4-Mediated
T158 28-32 NN denotes NFκB
T159 33-42 NN denotes Signaling
T160 43-45 IN denotes in
T161 46-57 NNP denotes Hemorrhagic
T162 58-63 NNP denotes Brain
T163 64-66 IN denotes in
T164 67-71 NN denotes Rats
T165 82-94 NN denotes Inflammation
T166 95-98 CC denotes and
T167 99-107 NN denotes immunity
T168 108-112 VB denotes play
T169 113-114 DT denotes a
T170 115-122 JJ denotes crucial
T171 123-127 NN denotes role
T172 128-130 IN denotes in
T173 131-134 DT denotes the
T174 135-147 NN denotes pathogenesis
T175 148-150 IN denotes of
T176 151-164 JJ denotes Intracerebral
T177 165-175 NN denotes hemorrhage
T178 176-177 -LRB- denotes (
T179 177-180 NN denotes ICH
T180 180-181 -RRB- denotes )
T181 183-192 JJ denotes Toll-like
T182 193-201 NN denotes receptor
T183 202-204 NN denotes 4-
T184 205-206 -LRB- denotes (
T185 206-211 NN denotes TLR4-
T186 211-212 -RRB- denotes )
T187 213-221 VB denotes mediated
T188 222-229 JJ denotes nuclear
T189 230-236 NN denotes factor
T190 237-244 NN denotes kappa-B
T191 245-246 -LRB- denotes (
T192 246-250 NN denotes NFκB
T193 250-251 -RRB- denotes )
T194 252-261 NN denotes signaling
T195 262-267 VB denotes plays
T196 268-276 JJ denotes critical
T197 277-282 NN denotes roles
T198 283-285 IN denotes in
T199 286-289 DT denotes the
T200 290-300 NN denotes activation
T201 301-304 CC denotes and
T202 305-315 NN denotes regulation
T203 316-318 IN denotes of
T204 319-331 JJ denotes inflammatory
T205 332-341 NN denotes responses
T206 342-344 IN denotes in
T207 345-352 JJ denotes injured
T208 353-358 NN denotes brain
T209 360-367 RB denotes However
T210 367-368 -COMMA- denotes ,
T211 369-372 DT denotes the
T212 373-384 NN denotes involvement
T213 385-387 IN denotes of
T214 388-401 JJ denotes TLR4-mediated
T215 402-406 NN denotes NFκB
T216 407-416 NN denotes signaling
T217 417-419 IN denotes in
T218 420-423 DT denotes the
T219 424-436 NN denotes pathogenesis
T220 437-439 IN denotes of
T221 440-443 NN denotes ICH
T222 444-451 VB denotes remains
T223 452-459 JJ denotes unknown
T224 461-464 DT denotes The
T225 465-472 JJ denotes present
T226 473-478 NN denotes study
T227 479-482 VB denotes was
T228 483-485 TO denotes to
T229 486-494 VB denotes evaluate
T230 495-498 DT denotes the
T231 499-507 JJ denotes temporal
T232 508-515 NN denotes profile
T233 516-518 IN denotes of
T234 519-522 DT denotes the
T235 523-533 NN denotes expression
T236 534-536 IN denotes of
T237 537-541 NN denotes TLR4
T238 542-545 CC denotes and
T239 546-549 DT denotes the
T240 550-560 NN denotes activation
T241 561-563 IN denotes of
T242 564-577 JJ denotes TLR4-mediated
T243 578-582 NN denotes NFκB
T244 583-592 NN denotes signaling
T245 593-595 IN denotes in
T246 596-601 NN denotes brain
T247 602-609 NN denotes tissues
T248 610-612 IN denotes of
T249 613-619 NNP denotes Wistar
T250 620-624 NN denotes rats
T251 625-630 IN denotes after
T252 631-634 NN denotes ICH
T253 636-640 NN denotes TLR4
T254 641-645 NN denotes mRNA
T255 646-649 CC denotes and
T256 650-657 NN denotes protein
T257 657-658 -COMMA- denotes ,
T258 659-662 DT denotes the
T259 663-678 NN denotes phosphorylation
T260 679-681 IN denotes of
T261 682-692 NN denotes inhibitors
T262 693-695 IN denotes of
T263 696-701 NN denotes kappa
T264 702-703 NN denotes B
T265 704-705 -LRB- denotes (
T266 705-711 NN denotes p-IκBα
T267 711-712 -RRB- denotes )
T268 712-713 -COMMA- denotes ,
T269 714-717 CC denotes and
T270 718-721 DT denotes the
T271 722-730 NN denotes activity
T272 731-733 IN denotes of
T273 734-738 NN denotes NFκB
T274 739-743 VB denotes were
T275 744-752 VB denotes examined
T276 753-755 IN denotes in
T277 756-767 JJ denotes hemorrhagic
T278 768-776 JJ denotes cerebral
T279 777-783 NN denotes tissue
T280 784-786 IN denotes by
T281 787-793 NN denotes Rt-PCR
T282 793-794 -COMMA- denotes ,
T283 795-802 JJ denotes Western
T284 803-808 NN denotes blots
T285 808-809 -COMMA- denotes ,
T286 810-830 NN denotes immunohistochemistry
T287 831-839 NN denotes staining
T288 839-840 -COMMA- denotes ,
T289 841-844 CC denotes and
T290 845-849 NN denotes EMSA
T291 851-859 VB denotes Compared
T292 860-864 IN denotes with
T293 865-871 NN denotes saline
T294 872-879 NN denotes control
T295 879-880 -COMMA- denotes ,
T296 881-884 DT denotes the
T297 885-889 NN denotes TLR4
T298 890-894 NN denotes mRNA
T299 895-898 CC denotes and
T300 899-906 NN denotes protein
T301 907-920 RB denotes significantly
T302 921-930 VB denotes increased
T303 931-939 VB denotes starting
T304 940-942 IN denotes at
T305 943-950 NN denotes 6 hours
T306 951-956 IN denotes after
T307 957-960 NN denotes ICH
T308 960-961 -COMMA- denotes ,
T309 962-968 VB denotes peaked
T310 969-971 IN denotes on
T311 972-975 DT denotes the
T312 976-979 JJ denotes 3rd
T313 980-983 NN denotes day
T314 984-989 IN denotes after
T315 990-993 NN denotes ICH
T316 993-994 -COMMA- denotes ,
T317 995-998 CC denotes and
T318 999-1003 RB denotes then
T319 1004-1013 VB denotes decreased
T320 1014-1017 CC denotes but
T321 1018-1023 RB denotes still
T322 1024-1034 VB denotes maintained
T323 1035-1037 IN denotes at
T324 1038-1039 DT denotes a
T325 1040-1046 JJ denotes higher
T326 1047-1052 NN denotes level
T327 1053-1055 IN denotes on
T328 1056-1059 DT denotes the
T329 1060-1063 JJ denotes 7th
T330 1064-1067 NN denotes day
T331 1068-1073 IN denotes after
T332 1074-1077 NN denotes ICH
T333 1078-1079 -LRB- denotes (
T334 1079-1080 NN denotes P
T335 1081-1082 SYM denotes <
T336 1083-1086 CD denotes .05
T337 1086-1087 -RRB- denotes )
T338 1089-1092 DT denotes The
T339 1093-1098 NN denotes level
T340 1099-1101 IN denotes of
T341 1102-1108 NN denotes p-IκBα
T342 1109-1112 CC denotes and
T343 1113-1116 DT denotes the
T344 1117-1125 NN denotes activity
T345 1126-1128 IN denotes of
T346 1129-1133 NN denotes NFκB
T347 1134-1138 RB denotes also
T348 1139-1148 VB denotes increased
T349 1149-1151 IN denotes in
T350 1152-1155 DT denotes the
T351 1156-1161 NN denotes brain
T352 1162-1167 IN denotes after
T353 1168-1171 NN denotes ICH
T354 1172-1180 VB denotes compared
T355 1181-1185 IN denotes with
T356 1186-1192 NN denotes saline
T357 1193-1200 NN denotes control
T358 1202-1205 DT denotes The
T359 1206-1213 JJ denotes present
T360 1214-1219 NN denotes study
T361 1220-1227 RB denotes firstly
T362 1228-1236 VB denotes suggests
T363 1237-1241 IN denotes that
T364 1242-1255 JJ denotes TLR4-mediated
T365 1256-1260 NN denotes NFκB
T366 1261-1270 NN denotes signaling
T367 1271-1283 VB denotes participates
T368 1284-1286 IN denotes in
T369 1287-1290 DT denotes the
T370 1291-1303 NN denotes pathogenesis
T371 1304-1306 IN denotes of
T372 1307-1310 NN denotes ICH
T373 1310-1311 -COMMA- denotes ,
T374 1312-1317 WDT denotes which
T375 1318-1321 MD denotes may
T376 1322-1328 VB denotes become
T377 1329-1330 DT denotes a
T378 1331-1342 JJ denotes therapeutic
T379 1343-1349 NN denotes target
T380 1350-1353 IN denotes for
T381 1354-1365 JJ denotes ICH-induced
T382 1366-1371 NN denotes brain
T383 1372-1378 NN denotes damage
T931 1397-1410 JJ denotes Intracerebral
T932 1411-1421 NN denotes hemorrhage
T933 1422-1423 -LRB- denotes (
T934 1423-1426 NN denotes ICH
T935 1426-1427 -RRB- denotes )
T936 1428-1438 VB denotes represents
T937 1439-1441 CD denotes 10
T938 1441-1442 NN denotes %
T939 1442-1445 CD denotes –15
T940 1445-1446 NN denotes %
T941 1447-1449 IN denotes of
T942 1450-1453 DT denotes all
T943 1454-1461 NN denotes strokes
T944 1462-1465 CC denotes and
T945 1466-1472 VB denotes occurs
T946 1473-1477 IN denotes with
T947 1478-1488 VB denotes increasing
T948 1489-1498 NN denotes frequency
T949 1499-1501 IN denotes as
T950 1502-1503 DT denotes a
T951 1504-1516 NN denotes complication
T952 1517-1519 IN denotes of
T953 1520-1523 DT denotes the
T954 1524-1536 JJ denotes thrombolytic
T955 1537-1546 NN denotes treatment
T956 1547-1549 IN denotes of
T957 1550-1558 JJ denotes ischemic
T958 1559-1565 NN denotes stroke
T959 1565-1566 -COMMA- denotes ,
T960 1567-1572 WDT denotes which
T961 1573-1575 VB denotes is
T962 1576-1586 VB denotes associated
T963 1587-1591 IN denotes with
T964 1592-1596 JJ denotes high
T965 1597-1606 NN denotes mortality
T966 1607-1610 CC denotes and
T967 1611-1617 JJ denotes severe
T968 1618-1628 NN denotes disability
T969 1629-1631 IN denotes in
T970 1632-1641 NN denotes survivors
T971 1642-1643 -LRB- denotes [
T972 1643-1644 CD denotes 1
T973 1644-1645 -COMMA- denotes ,
T974 1646-1647 CD denotes 2
T975 1647-1648 -RRB- denotes ]
T976 1650-1655 JJ denotes Local
T977 1656-1661 NN denotes brain
T978 1662-1668 NN denotes tissue
T979 1669-1680 NN denotes deformation
T980 1681-1688 VB denotes induces
T981 1689-1696 JJ denotes primary
T982 1697-1702 NN denotes brain
T983 1703-1709 NN denotes damage
T984 1710-1715 IN denotes after
T985 1716-1719 NN denotes ICH
T986 1719-1720 -COLON- denotes ;
T987 1721-1725 RB denotes more
T988 1726-1737 RB denotes importantly
T989 1737-1738 -COMMA- denotes ,
T990 1739-1742 DT denotes the
T991 1743-1757 NN denotes excitotoxicity
T992 1758-1761 CC denotes and
T993 1762-1774 JJ denotes inflammatory
T994 1775-1784 NN denotes responses
T995 1785-1787 IN denotes in
T996 1788-1791 DT denotes the
T997 1792-1797 NN denotes brain
T998 1798-1804 NN denotes tissue
T999 1805-1812 VB denotes induced
T1000 1813-1815 IN denotes by
T1001 1816-1819 NN denotes ICH
T1002 1820-1826 NN denotes result
T1003 1827-1829 IN denotes in
T1004 1830-1837 JJ denotes further
T1005 1838-1843 NN denotes brain
T1006 1844-1850 NN denotes damage
T1007 1851-1860 VB denotes following
T1008 1861-1864 NN denotes ICH
T1009 1865-1866 -LRB- denotes [
T1010 1866-1867 CD denotes 3
T1011 1867-1868 -RRB- denotes ]
T1012 1870-1874 CC denotes Both
T1013 1875-1881 JJ denotes innate
T1014 1882-1885 CC denotes and
T1015 1886-1894 JJ denotes adaptive
T1016 1895-1921 JJ denotes immunological/inflammatory
T1017 1922-1932 NN denotes mechanisms
T1018 1933-1937 VB denotes have
T1019 1938-1942 VB denotes been
T1020 1943-1950 RB denotes clearly
T1021 1951-1956 VB denotes shown
T1022 1957-1959 TO denotes to
T1023 1960-1971 VB denotes participate
T1024 1972-1974 IN denotes in
T1025 1975-1978 DT denotes the
T1026 1979-1990 NN denotes progression
T1027 1991-1993 IN denotes of
T1028 1994-1999 NN denotes brain
T1029 2000-2006 NN denotes injury
T1030 2007-2012 IN denotes after
T1031 2013-2021 JJ denotes ischemic
T1032 2022-2028 NN denotes stroke
T1033 2030-2042 RB denotes Nevertheless
T1034 2042-2043 -COMMA- denotes ,
T1035 2044-2047 WRB denotes how
T1036 2048-2051 DT denotes the
T1037 2052-2064 JJ denotes inflammatory
T1038 2065-2074 NN denotes responses
T1039 2075-2077 IN denotes in
T1040 2078-2081 NN denotes ICH
T1041 2082-2085 VB denotes are
T1042 2086-2095 VB denotes triggered
T1043 2096-2099 CC denotes and
T1044 2100-2109 VB denotes regulated
T1045 2110-2117 VB denotes remains
T1046 2118-2120 TO denotes to
T1047 2121-2123 VB denotes be
T1048 2124-2134 VB denotes elucidated
T1049 2136-2140 NN denotes TLRs
T1050 2141-2144 VB denotes are
T1051 2145-2146 DT denotes a
T1052 2147-2153 NN denotes family
T1053 2154-2156 IN denotes of
T1054 2157-2170 NN denotes transmembrane
T1055 2171-2179 NN denotes proteins
T1056 2180-2183 CC denotes and
T1057 2184-2187 VB denotes act
T1058 2188-2190 IN denotes as
T1059 2191-2197 NN denotes signal
T1060 2198-2210 NN denotes transduction
T1061 2211-2220 NN denotes molecules
T1062 2221-2222 -LRB- denotes [
T1063 2222-2223 CD denotes 4
T1064 2223-2224 -RRB- denotes ]
T1065 2226-2236 NN denotes Activation
T1066 2237-2239 IN denotes of
T1067 2240-2244 NN denotes TLRs
T1068 2245-2253 VB denotes recruits
T1069 2254-2264 JJ denotes downstream
T1070 2265-2274 NN denotes signaling
T1071 2275-2283 NN denotes proteins
T1072 2284-2287 CC denotes and
T1073 2288-2295 VB denotes results
T1074 2296-2298 IN denotes in
T1075 2299-2312 NN denotes transcription
T1076 2313-2315 IN denotes of
T1077 2316-2321 NN denotes genes
T1078 2322-2330 VB denotes encoding
T1079 2331-2354 JJ denotes inflammation-associated
T1080 2355-2364 NN denotes molecules
T1081 2365-2368 CC denotes and
T1082 2369-2378 NN denotes cytokines
T1083 2379-2380 -LRB- denotes [
T1084 2380-2381 CD denotes 5
T1085 2381-2382 -COMMA- denotes ,
T1086 2383-2384 CD denotes 6
T1087 2384-2385 -RRB- denotes ]
T1088 2387-2390 IN denotes For
T1089 2391-2398 NN denotes example
T1090 2398-2399 -COMMA- denotes ,
T1091 2400-2408 VB denotes combined
T1092 2409-2413 IN denotes with
T1093 2414-2422 JJ denotes specific
T1094 2423-2429 NN denotes ligand
T1095 2429-2430 -COMMA- denotes ,
T1096 2431-2434 DT denotes the
T1097 2435-2445 NN denotes activation
T1098 2446-2448 IN denotes of
T1099 2449-2453 NN denotes TLR4
T1100 2454-2461 VB denotes induces
T1101 2462-2465 DT denotes the
T1102 2466-2481 NN denotes phosphorylation
T1103 2482-2484 IN denotes of
T1104 2485-2494 NN denotes inhibitor
T1105 2495-2497 IN denotes of
T1106 2498-2505 NN denotes kappa-B
T1107 2506-2507 -LRB- denotes (
T1108 2507-2510 NN denotes IκB
T1109 2510-2511 -RRB- denotes )
T1110 2512-2515 CC denotes and
T1111 2516-2527 VB denotes dissociates
T1112 2528-2531 NN denotes IκB
T1113 2532-2536 IN denotes from
T1114 2537-2547 NN denotes NF-kappa-B
T1115 2548-2549 -LRB- denotes (
T1116 2549-2553 NN denotes NFκB
T1117 2553-2554 -RRB- denotes )
T1118 2556-2560 RB denotes Then
T1119 2560-2561 -COMMA- denotes ,
T1120 2562-2566 NN denotes NFκB
T1121 2567-2580 NN denotes trans-locates
T1122 2581-2585 IN denotes into
T1123 2586-2589 DT denotes the
T1124 2590-2597 NN denotes nucleus
T1125 2598-2601 CC denotes and
T1126 2602-2611 VB denotes activates
T1127 2612-2615 CC denotes and
T1128 2616-2625 VB denotes regulates
T1129 2626-2629 DT denotes the
T1130 2630-2643 NN denotes transcription
T1131 2644-2646 IN denotes of
T1132 2647-2652 NN denotes genes
T1133 2653-2660 VB denotes related
T1134 2661-2663 TO denotes to
T1135 2664-2676 JJ denotes inflammatory
T1136 2677-2686 NN denotes responses
T1137 2687-2688 -LRB- denotes [
T1138 2688-2689 CD denotes 5
T1139 2689-2690 -COMMA- denotes ,
T1140 2691-2692 CD denotes 6
T1141 2692-2693 -RRB- denotes ]
T1142 2695-2699 NN denotes TLRs
T1143 2700-2704 VB denotes play
T1144 2705-2706 DT denotes a
T1145 2707-2715 JJ denotes critical
T1146 2716-2720 NN denotes role
T1147 2721-2723 IN denotes in
T1148 2724-2727 DT denotes the
T1149 2728-2737 NN denotes induction
T1150 2738-2740 IN denotes of
T1151 2741-2767 JJ denotes immunological/inflammatory
T1152 2768-2777 NN denotes responses
T1153 2778-2781 CC denotes and
T1154 2782-2785 VB denotes are
T1155 2786-2796 VB denotes implicated
T1156 2797-2799 IN denotes in
T1157 2800-2807 JJ denotes several
T1158 2808-2811 NN denotes CNS
T1159 2812-2820 NN denotes diseases
T1160 2820-2821 -COMMA- denotes ,
T1161 2822-2826 JJ denotes such
T1162 2827-2829 IN denotes as
T1163 2830-2840 JJ denotes infectious
T1164 2841-2848 NN denotes disease
T1165 2848-2849 -COMMA- denotes ,
T1166 2850-2860 JJ denotes autoimmune
T1167 2861-2868 NN denotes disease
T1168 2868-2869 -COMMA- denotes ,
T1169 2870-2873 CC denotes and
T1170 2874-2882 JJ denotes ischemic
T1171 2883-2888 NN denotes brain
T1172 2889-2895 NN denotes injury
T1173 2896-2897 -LRB- denotes [
T1174 2897-2898 CD denotes 7
T1175 2898-2899 -COMMA- denotes ,
T1176 2900-2901 CD denotes 8
T1177 2901-2902 -RRB- denotes ]
T1178 2904-2916 VB denotes Accumulating
T1179 2917-2926 NN denotes evidences
T1180 2927-2938 VB denotes demonstrate
T1181 2939-2943 IN denotes that
T1182 2944-2948 NN denotes TLR4
T1183 2948-2949 -COMMA- denotes ,
T1184 2950-2953 DT denotes the
T1185 2954-2959 JJ denotes first
T1186 2960-2969 JJ denotes mammalian
T1187 2970-2973 NN denotes TLR
T1188 2974-2984 VB denotes recognized
T1189 2984-2985 -COMMA- denotes ,
T1190 2986-2997 VB denotes contributes
T1191 2998-3000 TO denotes to
T1192 3001-3004 DT denotes the
T1193 3005-3013 JJ denotes neuronal
T1194 3014-3019 NN denotes death
T1195 3019-3020 -COMMA- denotes ,
T1196 3021-3026 NN denotes blood
T1197 3027-3032 NN denotes brain
T1198 3033-3040 NN denotes barrier
T1199 3041-3047 NN denotes damage
T1200 3047-3048 -COMMA- denotes ,
T1201 3049-3054 NN denotes brain
T1202 3055-3060 NN denotes edema
T1203 3060-3061 -COMMA- denotes ,
T1204 3062-3065 CC denotes and
T1205 3066-3078 JJ denotes inflammatory
T1206 3079-3088 NN denotes responses
T1207 3089-3091 IN denotes in
T1208 3092-3095 DT denotes the
T1209 3096-3101 NN denotes brain
T1210 3102-3108 NN denotes injury
T1211 3109-3116 VB denotes induced
T1212 3117-3119 IN denotes by
T1213 3120-3128 NN denotes ischemia
T1214 3129-3130 -LRB- denotes [
T1215 3130-3131 CD denotes 8
T1216 3131-3132 -COMMA- denotes ,
T1217 3133-3134 CD denotes 9
T1218 3134-3135 -RRB- denotes ]
T1219 3137-3144 RB denotes However
T1220 3144-3145 -COMMA- denotes ,
T1221 3146-3152 JJ denotes little
T1222 3153-3155 VB denotes is
T1223 3156-3161 VB denotes known
T1224 3162-3167 IN denotes about
T1225 3168-3172 NN denotes TLR4
T1226 3173-3175 IN denotes in
T1227 3176-3179 DT denotes the
T1228 3180-3185 NN denotes brain
T1229 3186-3191 IN denotes after
T1230 3192-3195 NN denotes ICH
T1231 3197-3199 IN denotes In
T1232 3200-3203 DT denotes the
T1233 3204-3211 JJ denotes present
T1234 3212-3217 NN denotes study
T1235 3217-3218 -COMMA- denotes ,
T1236 3219-3221 PRP denotes we
T1237 3222-3230 VB denotes detected
T1238 3231-3234 DT denotes the
T1239 3235-3248 NN denotes transcription
T1240 3249-3251 IN denotes of
T1241 3252-3256 NN denotes TLR4
T1242 3257-3261 NN denotes gene
T1243 3262-3265 CC denotes and
T1244 3266-3269 DT denotes the
T1245 3270-3280 NN denotes activation
T1246 3281-3283 IN denotes of
T1247 3284-3297 JJ denotes TLR4-mediated
T1248 3298-3307 NN denotes signaling
T1249 3308-3310 IN denotes in
T1250 3311-3314 DT denotes the
T1251 3315-3318 NN denotes rat
T1252 3319-3325 NN denotes brains
T1253 3326-3335 VB denotes subjected
T1254 3336-3338 TO denotes to
T1255 3339-3351 JJ denotes experimental
T1256 3352-3355 NN denotes ICH
T1257 3357-3360 PRP-DOLLAR- denotes Our
T1258 3361-3365 NN denotes data
T1259 3366-3373 RB denotes firstly
T1260 3374-3382 VB denotes provided
T1261 3383-3386 DT denotes the
T1262 3387-3396 NN denotes knowledge
T1263 3397-3402 IN denotes about
T1264 3403-3406 DT denotes the
T1265 3407-3419 NN denotes distribution
T1266 3420-3422 IN denotes of
T1267 3423-3427 NN denotes TLR4
T1268 3428-3431 CC denotes and
T1269 3432-3435 DT denotes the
T1270 3436-3444 JJ denotes temporal
T1271 3445-3452 NN denotes profile
T1272 3453-3455 IN denotes of
T1273 3456-3459 DT denotes the
T1274 3460-3470 NN denotes activation
T1275 3471-3473 IN denotes of
T1276 3474-3487 JJ denotes TLR4-mediated
T1277 3488-3497 NN denotes signaling
T1278 3498-3500 IN denotes in
T1279 3501-3504 NN denotes rat
T1280 3505-3510 NN denotes brain
T1281 3511-3517 NN denotes tissue
T1282 3518-3523 IN denotes after
T1283 3524-3527 NN denotes ICH
T1776 3542-3545 CD denotes 2.1
T1777 3547-3554 NN denotes Animals
T1778 3555-3561 NNP denotes Ninety
T1779 3562-3568 NNP denotes Wister
T1780 3569-3573 NN denotes rats
T1781 3574-3575 -LRB- denotes (
T1782 3575-3579 NN denotes male
T1783 3579-3580 -COMMA- denotes ,
T1784 3581-3585 NN denotes body
T1785 3586-3592 NN denotes weight
T1786 3592-3593 -COLON- denotes :
T1787 3594-3599 CD denotes 250 g
T1788 3600-3602 TO denotes to
T1789 3603-3608 CD denotes 300 g
T1790 3608-3609 -RRB- denotes )
T1791 3610-3614 VB denotes were
T1792 3615-3623 VB denotes provided
T1793 3624-3626 IN denotes by
T1794 3627-3639 NNP denotes Experimental
T1795 3640-3646 NNP denotes Animal
T1796 3647-3653 NNP denotes Center
T1797 3653-3654 -COMMA- denotes ,
T1798 3655-3660 NNP denotes China
T1799 3661-3668 NNP denotes Medical
T1800 3669-3680 NNP denotes University.
T1801 3681-3684 DT denotes The
T1802 3685-3689 NN denotes rats
T1803 3690-3694 VB denotes were
T1804 3695-3703 VB denotes assigned
T1805 3704-3712 RB denotes randomly
T1806 3713-3715 TO denotes to
T1807 3716-3721 CD denotes three
T1808 3722-3728 NN denotes groups
T1809 3728-3729 -COLON- denotes :
T1810 3730-3736 JJ denotes normal
T1811 3737-3742 NN denotes group
T1812 3743-3744 -LRB- denotes (
T1813 3744-3745 NN denotes N
T1814 3745-3746 -COMMA- denotes ,
T1815 3747-3748 NN denotes n
T1816 3749-3750 SYM denotes =
T1817 3751-3753 CD denotes 10
T1818 3753-3754 -COMMA- denotes ,
T1819 3755-3762 IN denotes without
T1820 3763-3766 DT denotes any
T1821 3767-3776 NN denotes treatment
T1822 3776-3777 -RRB- denotes )
T1823 3777-3778 -COMMA- denotes ,
T1824 3779-3785 JJ denotes normal
T1825 3786-3792 NN denotes saline
T1826 3793-3800 NN denotes control
T1827 3801-3802 -LRB- denotes (
T1828 3802-3803 NN denotes S
T1829 3803-3804 -COMMA- denotes ,
T1830 3805-3806 NN denotes n
T1831 3807-3808 SYM denotes =
T1832 3809-3811 CD denotes 40
T1833 3811-3812 -COMMA- denotes ,
T1834 3813-3827 JJ denotes intra-cerebral
T1835 3828-3837 NN denotes injection
T1836 3838-3840 IN denotes of
T1837 3841-3847 JJ denotes normal
T1838 3848-3854 NN denotes saline
T1839 3855-3857 IN denotes as
T1840 3858-3865 NN denotes control
T1841 3865-3866 -RRB- denotes )
T1842 3867-3870 CC denotes and
T1843 3871-3885 JJ denotes intra-cerebral
T1844 3886-3896 NN denotes hemorrhage
T1845 3897-3902 NN denotes group
T1846 3903-3904 -LRB- denotes (
T1847 3904-3907 NN denotes ICH
T1848 3907-3908 -COMMA- denotes ,
T1849 3909-3910 NN denotes n
T1850 3911-3912 SYM denotes =
T1851 3913-3915 CD denotes 40
T1852 3915-3916 -RRB- denotes )
T1853 3918-3921 DT denotes The
T1854 3922-3934 JJ denotes experimental
T1855 3935-3943 NN denotes protocol
T1856 3944-3948 VB denotes used
T1857 3949-3952 IN denotes for
T1858 3953-3960 NN denotes animals
T1859 3961-3964 VB denotes was
T1860 3965-3973 VB denotes approved
T1861 3974-3976 IN denotes by
T1862 3977-3980 DT denotes the
T1863 3981-3987 NNP denotes Animal
T1864 3988-3992 NNP denotes Care
T1865 3993-3996 CC denotes and
T1866 3997-4000 NNP denotes Use
T1867 4001-4010 NNP denotes Committee
T1868 4010-4011 -COMMA- denotes ,
T1869 4012-4017 NNP denotes China
T1870 4018-4025 NNP denotes Medical
T1871 4026-4037 NNP denotes University.
T1872 4038-4041 DT denotes The
T1873 4042-4046 NN denotes rats
T1874 4047-4051 VB denotes were
T1875 4052-4061 VB denotes subjected
T1876 4062-4064 TO denotes to
T1877 4065-4079 JJ denotes intra-cerebral
T1878 4080-4089 NN denotes injection
T1879 4090-4092 IN denotes of
T1880 4093-4099 JJ denotes normal
T1881 4100-4106 NN denotes saline
T1882 4107-4109 CC denotes or
T1883 4110-4120 JJ denotes autologous
T1884 4121-4126 JJ denotes whole
T1885 4127-4132 NN denotes blood
T1886 4133-4136 CC denotes and
T1887 4137-4141 VB denotes were
T1888 4142-4152 VB denotes sacrificed
T1889 4153-4155 IN denotes on
T1890 4156-4163 NN denotes 6 hours
T1891 4163-4164 -COMMA- denotes ,
T1892 4165-4166 CD denotes 1
T1893 4167-4170 NN denotes day
T1894 4170-4171 -COMMA- denotes ,
T1895 4172-4173 CD denotes 3
T1896 4174-4178 NN denotes days
T1897 4179-4182 CC denotes and
T1898 4183-4184 CD denotes 7
T1899 4185-4189 NN denotes days
T1900 4190-4195 IN denotes after
T1901 4196-4199 DT denotes the
T1902 4200-4209 NN denotes injection
T1903 4209-4210 -COMMA- denotes ,
T1904 4211-4223 RB denotes respectively
T1905 4225-4229 CD denotes Five
T1906 4230-4234 NN denotes rats
T1907 4235-4237 IN denotes in
T1908 4238-4242 DT denotes each
T1909 4243-4248 NN denotes group
T1910 4249-4251 IN denotes at
T1911 4252-4256 DT denotes each
T1912 4257-4261 NN denotes time
T1913 4262-4267 NN denotes point
T1914 4268-4272 VB denotes were
T1915 4273-4283 VB denotes sacrificed
T1916 4284-4286 IN denotes by
T1917 4287-4301 RB denotes transcardially
T1918 4302-4311 NN denotes perfusion
T1919 4312-4314 IN denotes of
T1920 4315-4321 JJ denotes normal
T1921 4322-4328 NN denotes saline
T1922 4329-4337 VB denotes followed
T1923 4338-4340 IN denotes by
T1924 4341-4342 CD denotes 4
T1925 4342-4343 NN denotes %
T1926 4344-4352 VB denotes buffered
T1927 4353-4357 NNP denotes Para
T1928 4358-4370 NN denotes formaldehyde
T1929 4371-4372 -LRB- denotes (
T1930 4372-4374 NN denotes pH
T1931 4375-4376 SYM denotes =
T1932 4377-4380 CD denotes 7.4
T1933 4380-4381 -RRB- denotes )
T1934 4383-4386 DT denotes The
T1935 4387-4393 NN denotes brains
T1936 4394-4398 VB denotes were
T1937 4399-4406 VB denotes removed
T1938 4406-4407 -COMMA- denotes ,
T1939 4408-4417 VB denotes postfixed
T1940 4417-4418 -COMMA- denotes ,
T1941 4419-4427 VB denotes embedded
T1942 4428-4430 IN denotes in
T1943 4431-4439 NN denotes paraffin
T1944 4439-4440 -COMMA- denotes ,
T1945 4441-4444 CC denotes and
T1946 4445-4448 VB denotes cut
T1947 4449-4453 IN denotes into
T1948 4454-4462 NN denotes sections
T1949 4463-4464 -LRB- denotes (
T1950 4464-4468 NN denotes 7 μm
T1951 4468-4469 -RRB- denotes )
T1952 4470-4472 IN denotes as
T1953 4473-4482 VB denotes described
T1954 4483-4493 RB denotes previously
T1955 4494-4495 -LRB- denotes [
T1956 4495-4496 CD denotes 8
T1957 4496-4497 -RRB- denotes ]
T1958 4499-4503 CD denotes Five
T1959 4504-4508 NN denotes rats
T1960 4509-4511 IN denotes in
T1961 4512-4516 DT denotes each
T1962 4517-4522 NN denotes group
T1963 4523-4525 IN denotes at
T1964 4526-4530 DT denotes each
T1965 4531-4535 NN denotes time
T1966 4536-4541 NN denotes point
T1967 4542-4546 VB denotes were
T1968 4547-4557 VB denotes sacrificed
T1969 4558-4560 IN denotes by
T1970 4561-4565 IN denotes over
T1971 4566-4570 NN denotes dose
T1972 4571-4580 NN denotes injection
T1973 4581-4583 IN denotes of
T1974 4584-4593 NNP denotes Ketamine.
T1975 4594-4597 DT denotes The
T1976 4598-4604 NN denotes brains
T1977 4605-4609 VB denotes were
T1978 4610-4617 VB denotes removed
T1979 4618-4621 CC denotes and
T1980 4622-4628 VB denotes stored
T1981 4629-4631 IN denotes at
T1982 4632-4637 CC denotes minus
T1983 4638-4642 NN denotes 80°C
T1984 4643-4646 IN denotes for
T1985 4647-4653 NN denotes RT-PCR
T1986 4654-4657 CC denotes and
T1987 4658-4665 JJ denotes Western
T1988 4666-4671 NN denotes Blots
T2254 4674-4677 CD denotes 2.2
T2255 4679-4688 NN denotes Induction
T2256 4689-4691 IN denotes of
T2257 4692-4705 JJ denotes Intracerebral
T2258 4706-4716 NNP denotes Hemorrhage
T2259 4717-4722 IN denotes Since
T2260 4723-4727 JJ denotes most
T2261 4728-4741 JJ denotes intracerebral
T2262 4742-4753 NN denotes hemorrhages
T2263 4754-4759 VB denotes occur
T2264 4760-4762 IN denotes in
T2265 4763-4766 DT denotes the
T2266 4767-4772 JJ denotes basal
T2267 4773-4780 NN denotes ganglia
T2268 4781-4791 RB denotes clinically
T2269 4791-4792 -COMMA- denotes ,
T2270 4793-4795 IN denotes in
T2271 4796-4799 DT denotes the
T2272 4800-4807 JJ denotes present
T2273 4808-4813 NN denotes study
T2274 4813-4814 -COMMA- denotes ,
T2275 4815-4818 NN denotes rat
T2276 4819-4824 NN denotes model
T2277 4825-4827 IN denotes of
T2278 4828-4831 NN denotes ICH
T2279 4832-4835 VB denotes was
T2280 4836-4843 VB denotes induced
T2281 4844-4846 IN denotes in
T2282 4847-4851 JJ denotes left
T2283 4852-4857 JJ denotes basal
T2284 4858-4865 NN denotes ganglia
T2285 4867-4871 NN denotes Rats
T2286 4872-4876 VB denotes were
T2287 4877-4889 VB denotes anesthetized
T2288 4890-4894 IN denotes with
T2289 4895-4911 JJ denotes intra-peritoneal
T2290 4912-4918 NN denotes sodium
T2291 4919-4932 NN denotes pentobarbital
T2292 4933-4934 -LRB- denotes (
T2293 4934-4942 NN denotes 60 mg/kg
T2294 4942-4943 -RRB- denotes )
T2295 4945-4948 DT denotes The
T2296 4949-4953 NN denotes body
T2297 4954-4955 -LRB- denotes (
T2298 4955-4961 JJ denotes rectal
T2299 4961-4962 -RRB- denotes )
T2300 4963-4974 NN denotes temperature
T2301 4975-4978 VB denotes was
T2302 4979-4989 VB denotes maintained
T2303 4990-4992 IN denotes at
T2304 4993-4997 NN denotes 37°C
T2305 4998-5004 IN denotes during
T2306 5005-5008 DT denotes the
T2307 5009-5016 NN denotes surgery
T2308 5017-5022 VB denotes using
T2309 5023-5024 DT denotes a
T2310 5025-5044 JJ denotes feedback-controlled
T2311 5045-5052 NN denotes heating
T2312 5053-5059 NN denotes system
T2313 5061-5064 DT denotes The
T2314 5065-5069 NN denotes rats
T2315 5070-5074 VB denotes were
T2316 5075-5085 VB denotes positioned
T2317 5086-5088 IN denotes in
T2318 5089-5090 DT denotes a
T2319 5091-5103 JJ denotes stereotactic
T2320 5104-5109 NN denotes frame
T2321 5109-5110 -COMMA- denotes ,
T2322 5111-5114 CC denotes and
T2323 5115-5118 DT denotes the
T2324 5119-5124 NN denotes scalp
T2325 5125-5128 VB denotes was
T2326 5129-5136 VB denotes incised
T2327 5137-5142 IN denotes along
T2328 5143-5146 DT denotes the
T2329 5147-5154 NN denotes midline
T2330 5156-5161 VB denotes Using
T2331 5162-5163 DT denotes a
T2332 5164-5171 JJ denotes sterile
T2333 5172-5181 NN denotes technique
T2334 5181-5182 -COMMA- denotes ,
T2335 5183-5184 DT denotes a
T2336 5185-5189 NN denotes 1 mm
T2337 5190-5194 NN denotes burr
T2338 5195-5199 NN denotes hole
T2339 5200-5203 VB denotes was
T2340 5204-5210 VB denotes opened
T2341 5211-5213 IN denotes in
T2342 5214-5217 DT denotes the
T2343 5218-5223 NN denotes skull
T2344 5224-5226 IN denotes on
T2345 5227-5230 DT denotes the
T2346 5231-5235 JJ denotes left
T2347 5236-5243 JJ denotes coronal
T2348 5244-5250 NN denotes suture
T2349 5251-5255 NN denotes 3 mm
T2350 5256-5263 JJ denotes lateral
T2351 5264-5266 TO denotes to
T2352 5267-5270 DT denotes the
T2353 5271-5278 NN denotes midline
T2354 5280-5281 DT denotes A
T2355 5282-5287 JJ denotes blunt
T2356 5288-5296 JJ denotes 26-gauge
T2357 5297-5303 NN denotes needle
T2358 5304-5307 VB denotes was
T2359 5308-5316 VB denotes inserted
T2360 5317-5321 IN denotes into
T2361 5322-5325 DT denotes the
T2362 5326-5330 JJ denotes left
T2363 5331-5336 JJ denotes basal
T2364 5337-5344 NN denotes ganglia
T2365 5345-5350 IN denotes under
T2366 5351-5363 JJ denotes stereotactic
T2367 5364-5372 NN denotes guidance
T2368 5373-5374 -LRB- denotes (
T2369 5374-5385 NN denotes coordinates
T2370 5385-5386 -COLON- denotes :
T2371 5387-5393 CD denotes 0.2 mm
T2372 5394-5402 JJ denotes anterior
T2373 5402-5403 -COMMA- denotes ,
T2374 5404-5410 NN denotes 6.0 mm
T2375 5411-5418 JJ denotes ventral
T2376 5418-5419 -COMMA- denotes ,
T2377 5420-5423 CC denotes and
T2378 5424-5430 NN denotes 3.0 mm
T2379 5431-5438 JJ denotes lateral
T2380 5439-5441 TO denotes to
T2381 5442-5445 DT denotes the
T2382 5446-5453 NN denotes midline
T2383 5453-5454 -RRB- denotes )
T2384 5456-5460 RB denotes Then
T2385 5460-5461 -COMMA- denotes ,
T2386 5462-5463 DT denotes a
T2387 5464-5469 NN denotes 75 μL
T2388 5470-5472 IN denotes of
T2389 5473-5483 JJ denotes autologous
T2390 5484-5489 JJ denotes whole
T2391 5490-5495 NN denotes blood
T2392 5496-5499 VB denotes was
T2393 5500-5507 VB denotes infused
T2394 5508-5510 IN denotes at
T2395 5511-5512 DT denotes a
T2396 5513-5517 NN denotes rate
T2397 5518-5520 IN denotes of
T2398 5521-5530 NN denotes 20 μL/min
T2399 5531-5535 IN denotes with
T2400 5536-5539 DT denotes the
T2401 5540-5543 NN denotes use
T2402 5544-5546 IN denotes of
T2403 5547-5548 DT denotes a
T2404 5549-5562 NN denotes microinfusion
T2405 5563-5567 NN denotes pump
T2406 5569-5574 IN denotes After
T2407 5575-5578 DT denotes the
T2408 5579-5589 NN denotes completion
T2409 5590-5592 IN denotes of
T2410 5593-5596 DT denotes the
T2411 5597-5605 NN denotes infusion
T2412 5605-5606 -COMMA- denotes ,
T2413 5607-5610 DT denotes the
T2414 5611-5617 NN denotes needle
T2415 5618-5621 VB denotes was
T2416 5622-5631 VB denotes withdrawn
T2417 5632-5639 RB denotes quickly
T2418 5639-5640 -COMMA- denotes ,
T2419 5641-5654 NN denotes cyanoacrylate
T2420 5655-5659 NN denotes glue
T2421 5660-5663 VB denotes was
T2422 5664-5670 VB denotes placed
T2423 5671-5677 IN denotes around
T2424 5678-5681 DT denotes the
T2425 5682-5686 NN denotes burr
T2426 5687-5691 NN denotes hole
T2427 5691-5692 -COMMA- denotes ,
T2428 5693-5696 CC denotes and
T2429 5697-5700 DT denotes the
T2430 5701-5705 NN denotes skin
T2431 5706-5714 NN denotes incision
T2432 5715-5718 VB denotes was
T2433 5719-5725 VB denotes closed
T2434 5726-5730 IN denotes with
T2435 5731-5738 NN denotes sutures
T2436 5740-5743 IN denotes For
T2437 5744-5747 DT denotes the
T2438 5748-5754 JJ denotes normal
T2439 5755-5761 NN denotes saline
T2440 5762-5769 NN denotes control
T2441 5770-5774 NN denotes rats
T2442 5774-5775 -COMMA- denotes ,
T2443 5776-5780 RB denotes only
T2444 5781-5786 NN denotes 75 μL
T2445 5787-5793 JJ denotes normal
T2446 5794-5800 NN denotes saline
T2447 5801-5804 VB denotes was
T2448 5805-5813 VB denotes injected
T2816 5816-5819 CD denotes 2.3
T2817 5821-5830 NN denotes Detection
T2818 5831-5833 IN denotes of
T2819 5834-5838 NN denotes TLR4
T2820 5839-5843 NN denotes mRNA
T2821 5844-5846 IN denotes by
T2822 5847-5850 DT denotes the
T2823 5851-5857 NN denotes Method
T2824 5858-5860 IN denotes of
T2825 5861-5867 NN denotes RT-PCR
T2826 5868-5875 RB denotes Briefly
T2827 5875-5876 -COMMA- denotes ,
T2828 5877-5882 JJ denotes total
T2829 5883-5886 NN denotes RNA
T2830 5887-5894 NN denotes samples
T2831 5895-5899 VB denotes were
T2832 5900-5908 VB denotes isolated
T2833 5909-5913 IN denotes from
T2834 5914-5929 JJ denotes peri-hemorrhage
T2835 5930-5937 NN denotes regions
T2836 5938-5940 IN denotes in
T2837 5941-5945 JJ denotes left
T2838 5946-5951 JJ denotes basal
T2839 5952-5959 NN denotes ganglia
T2840 5960-5965 VB denotes using
T2841 5966-5972 NNP denotes Simply
T2842 5973-5974 NNP denotes P
T2843 5975-5980 NNP denotes Total
T2844 5981-5984 NN denotes RNA
T2845 5985-5994 NN denotes isolation
T2846 5995-5998 NN denotes Kit
T2847 5999-6000 -LRB- denotes (
T2848 6000-6007 NNP denotes BioFlux
T2849 6007-6008 -COMMA- denotes ,
T2850 6009-6011 NNP denotes HZ
T2851 6011-6012 -COMMA- denotes ,
T2852 6013-6018 NNP denotes China
T2853 6018-6019 -RRB- denotes )
T2854 6020-6029 VB denotes according
T2855 6030-6032 TO denotes to
T2856 6033-6036 DT denotes the
T2857 6037-6049 NN denotes manufacturer
T2858 6049-6051 POS denotes 's
T2859 6052-6064 NN denotes instructions
T2860 6066-6069 DT denotes The
T2861 6070-6078 NN denotes quantity
T2862 6079-6081 IN denotes of
T2863 6082-6087 JJ denotes total
T2864 6088-6091 NN denotes RNA
T2865 6092-6095 VB denotes was
T2866 6096-6106 VB denotes determined
T2867 6107-6109 IN denotes on
T2868 6110-6111 DT denotes a
T2869 6112-6120 NNP denotes Nanodrop
T2870 6121-6122 -LRB- denotes (
T2871 6122-6129 NN denotes ND-1000
T2872 6130-6147 NN denotes Spectrophotometer
T2873 6147-6148 -RRB- denotes )
T2874 6149-6151 IN denotes by
T2875 6152-6161 VB denotes measuring
T2876 6162-6169 JJ denotes optical
T2877 6170-6177 NN denotes density
T2878 6178-6180 IN denotes at
T2879 6181-6185 NN denotes A260
T2880 6186-6189 CC denotes and
T2881 6190-6197 NN denotes A280 nm
T2882 6198-6208 NN denotes wavelength
T2883 6210-6214 RB denotes Then
T2884 6214-6215 -COMMA- denotes ,
T2885 6216-6219 DT denotes the
T2886 6220-6234 NN denotes concentrations
T2887 6235-6237 IN denotes of
T2888 6238-6242 NN denotes mRNA
T2889 6243-6247 VB denotes were
T2890 6248-6256 VB denotes adjusted
T2891 6257-6259 TO denotes to
T2892 6260-6268 NN denotes 1.0 g/mL
T2893 6270-6273 NN denotes RNA
T2894 6274-6277 VB denotes was
T2895 6278-6297 VB denotes reverse-transcribed
T2896 6298-6302 IN denotes into
T2897 6303-6307 NN denotes cDNA
T2898 6308-6310 IN denotes in
T2899 6311-6316 NN denotes 20 μL
T2900 6317-6325 NN denotes reaction
T2901 6326-6332 NN denotes system
T2902 6333-6338 VB denotes using
T2903 6339-6350 NNP denotes Superscript
T2904 6351-6363 NNP denotes First-Strand
T2905 6364-6373 NNP denotes Synthesis
T2906 6374-6377 NN denotes Kit
T2907 6378-6381 IN denotes for
T2908 6382-6388 NN denotes RT-PCR
T2909 6389-6390 -LRB- denotes (
T2910 6390-6397 JJ denotes promega
T2911 6398-6401 NNP denotes Inc
T2912 6401-6402 -RRB- denotes )
T2913 6403-6408 IN denotes under
T2914 6409-6419 NN denotes conditions
T2915 6420-6429 VB denotes described
T2916 6430-6432 IN denotes by
T2917 6433-6436 DT denotes the
T2918 6437-6445 NN denotes supplier
T2919 6447-6450 CD denotes One
T2920 6451-6461 NN denotes microliter
T2921 6462-6464 IN denotes of
T2922 6465-6469 NN denotes cDNA
T2923 6470-6473 VB denotes was
T2924 6474-6478 VB denotes used
T2925 6479-6481 TO denotes to
T2926 6482-6489 VB denotes amplify
T2927 6490-6493 DT denotes the
T2928 6494-6498 NN denotes TLR4
T2929 6499-6503 NN denotes gene
T2930 6504-6512 NN denotes fragment
T2931 6513-6517 IN denotes with
T2932 6518-6520 NN denotes 1×
T2933 6521-6524 NN denotes PCR
T2934 6525-6531 NN denotes buffer
T2935 6531-6532 -COMMA- denotes ,
T2936 6533-6545 NN denotes 1.5 mM MgCl2
T2937 6545-6546 -COMMA- denotes ,
T2938 6547-6553 NN denotes 200 μM
T2939 6554-6556 IN denotes of
T2940 6557-6561 DT denotes each
T2941 6562-6566 NN denotes dNTP
T2942 6566-6567 -COMMA- denotes ,
T2943 6568-6574 NN denotes 200 μM
T2944 6575-6577 IN denotes of
T2945 6578-6585 NN denotes primers
T2946 6585-6586 -COMMA- denotes ,
T2947 6587-6590 CC denotes and
T2948 6591-6593 NN denotes 2u
T2949 6594-6597 NN denotes Taq
T2950 6598-6601 NN denotes DNA
T2951 6602-6612 NN denotes polymerase
T2952 6614-6617 DT denotes The
T2953 6618-6623 NN denotes house
T2954 6624-6628 NN denotes keep
T2955 6629-6633 NN denotes gene
T2956 6634-6635 -LRB- denotes (
T2957 6635-6642 NN denotes β-actin
T2958 6642-6643 -RRB- denotes )
T2959 6644-6647 VB denotes was
T2960 6648-6652 VB denotes used
T2961 6653-6655 IN denotes as
T2962 6656-6658 DT denotes an
T2963 6659-6667 JJ denotes internal
T2964 6668-6675 NN denotes control
T2965 6677-6680 DT denotes The
T2966 6681-6684 NN denotes PCR
T2967 6685-6691 NN denotes primer
T2968 6692-6701 NN denotes sequences
T2969 6702-6706 VB denotes were
T2970 6707-6715 VB denotes designed
T2971 6716-6725 VB denotes according
T2972 6726-6728 TO denotes to
T2973 6729-6732 DT denotes the
T2974 6733-6737 NN denotes TLR4
T2975 6738-6741 CC denotes and
T2976 6742-6749 JJ denotes β-actin
T2977 6750-6754 NN denotes gene
T2978 6755-6764 NN denotes sequences
T2979 6765-6773 VB denotes reported
T2980 6774-6776 IN denotes in
T2981 6777-6784 NNP denotes GenBank
T2982 6786-6790 NN denotes TLR4
T2983 6791-6792 -LRB- denotes (
T2984 6792-6798 NN denotes 145 bp
T2985 6798-6799 -RRB- denotes )
T2986 6799-6800 -COLON- denotes :
T2987 6801-6808 RB denotes forward
T2988 6808-6809 -COLON- denotes :
T2989 6810-6836 NN denotes 5′-AGCTTTGGTCAGTTGGCTCT-3′
T2990 6836-6837 -COLON- denotes ;
T2991 6838-6845 NN denotes reverse
T2992 6845-6846 -COLON- denotes :
T2993 6847-6873 NN denotes 5′-CAGGATGACACCATTGAAGC-3′
T2994 6873-6874 -COLON- denotes ;
T2995 6875-6882 NN denotes β-actin
T2996 6883-6884 -LRB- denotes (
T2997 6884-6890 NN denotes 701 bp
T2998 6890-6891 -RRB- denotes )
T2999 6891-6892 -COLON- denotes :
T3000 6893-6900 RB denotes forward
T3001 6900-6901 -COLON- denotes :
T3002 6902-6927 NN denotes 5′-GCCAACCGTGAAAAAGATG-3′
T3003 6927-6928 -COLON- denotes ;
T3004 6929-6936 NN denotes reverse
T3005 6936-6937 -COLON- denotes :
T3006 6938-6963 NN denotes 5′-CCAGGATAGAGCCACCAAT-3′
T3007 6965-6973 NN denotes Reaction
T3008 6974-6980 NN denotes cycles
T3009 6981-6985 VB denotes were
T3010 6986-6995 VB denotes performed
T3011 6996-6998 IN denotes at
T3012 6999-7002 DT denotes the
T3013 7003-7012 VB denotes following
T3014 7013-7022 NN denotes condition
T3015 7022-7023 -COLON- denotes :
T3016 7024-7028 NN denotes 94°C
T3017 7029-7034 NN denotes 2 min
T3018 7034-7035 -COMMA- denotes ,
T3019 7036-7040 NN denotes 94°C
T3020 7041-7045 NN denotes 40 s
T3021 7045-7046 -COMMA- denotes ,
T3022 7047-7051 NN denotes 55°C
T3023 7052-7056 NN denotes 40 s
T3024 7056-7057 -COMMA- denotes ,
T3025 7058-7061 CC denotes and
T3026 7062-7066 NN denotes 72°C
T3027 7067-7071 NN denotes 60 s
T3028 7073-7076 DT denotes The
T3029 7077-7085 NN denotes reaction
T3030 7086-7089 VB denotes was
T3031 7090-7097 VB denotes stopped
T3032 7098-7103 IN denotes after
T3033 7104-7106 CD denotes 31
T3034 7107-7113 NN denotes cycles
T3035 7115-7118 NN denotes PCR
T3036 7119-7127 NN denotes products
T3037 7128-7132 VB denotes were
T3038 7133-7148 VB denotes electrophoresed
T3039 7149-7156 IN denotes through
T3040 7157-7164 NN denotes agarose
T3041 7165-7168 NN denotes gel
T3042 7170-7175 NN denotes Image
T3043 7176-7187 NNP denotes Acquisition
T3044 7188-7191 CC denotes and
T3045 7192-7200 NN denotes Analysis
T3046 7201-7209 NN denotes software
T3047 7210-7214 VB denotes were
T3048 7215-7219 VB denotes used
T3049 7220-7222 TO denotes to
T3050 7223-7232 VB denotes determine
T3051 7233-7237 NN denotes band
T3052 7238-7247 NN denotes densities
T3053 7249-7252 DT denotes The
T3054 7253-7262 NN denotes abundance
T3055 7263-7265 IN denotes of
T3056 7266-7270 NN denotes TLR4
T3057 7271-7275 NN denotes mRNA
T3058 7276-7279 VB denotes was
T3059 7280-7289 VB denotes expressed
T3060 7290-7292 IN denotes as
T3061 7293-7296 DT denotes the
T3062 7297-7302 NN denotes ratio
T3063 7303-7305 IN denotes of
T3064 7306-7310 NN denotes TLR4
T3065 7311-7315 NN denotes mRNA
T3066 7316-7318 TO denotes to
T3067 7319-7326 NN denotes β-actin
T3068 7327-7331 NN denotes mRNA
T3541 7334-7337 CD denotes 2.4
T3542 7339-7359 NN denotes Immunohistochemistry
T3543 7360-7361 -LRB- denotes (
T3544 7361-7364 NN denotes IHC
T3545 7364-7365 -RRB- denotes )
T3546 7366-7369 DT denotes The
T3547 7370-7373 NN denotes IHC
T3548 7374-7382 NN denotes staining
T3549 7383-7386 IN denotes for
T3550 7387-7391 NN denotes TLR4
T3551 7392-7395 VB denotes was
T3552 7396-7405 VB denotes performed
T3553 7406-7408 IN denotes as
T3554 7409-7418 VB denotes described
T3555 7419-7429 RB denotes previously
T3556 7430-7431 -LRB- denotes [
T3557 7431-7432 CD denotes 8
T3558 7432-7433 -RRB- denotes ]
T3559 7435-7438 DT denotes The
T3560 7439-7446 JJ denotes primary
T3561 7447-7455 NN denotes antibody
T3562 7456-7464 VB denotes employed
T3563 7465-7468 VB denotes was
T3564 7469-7475 NN denotes rabbit
T3565 7476-7485 NN denotes anti-TLR4
T3566 7486-7487 -LRB- denotes (
T3567 7487-7492 NNP denotes WuHan
T3568 7492-7493 -COMMA- denotes ,
T3569 7494-7500 NN denotes BA1717
T3570 7500-7501 -RRB- denotes )
T3571 7503-7506 DT denotes The
T3572 7507-7519 VB denotes biotinylated
T3573 7520-7529 JJ denotes secondary
T3574 7530-7538 NN denotes antibody
T3575 7539-7542 CC denotes and
T3576 7543-7576 JJ denotes antibody-biotin-avidin-peroxidase
T3577 7577-7586 NN denotes complexes
T3578 7587-7588 -LRB- denotes (
T3579 7588-7591 NN denotes ABC
T3580 7592-7599 NN denotes reagent
T3581 7599-7600 -COMMA- denotes ,
T3582 7601-7608 NN denotes SC-2018
T3583 7608-7609 -RRB- denotes )
T3584 7610-7614 VB denotes were
T3585 7615-7623 VB denotes obtained
T3586 7624-7628 IN denotes from
T3587 7629-7634 NNP denotes Santa
T3588 7635-7639 NNP denotes Cruz
T3589 7640-7653 NNP denotes Biotechnology
T3590 7654-7658 NNP denotes Inc.
T3591 7659-7660 -LRB- denotes (
T3592 7660-7665 NNP denotes Santa
T3593 7666-7670 NNP denotes Cruz
T3594 7670-7671 -COMMA- denotes ,
T3595 7672-7674 NNP denotes CA
T3596 7674-7675 -RRB- denotes )
T3597 7677-7683 NN denotes Slides
T3598 7684-7693 VB denotes processed
T3599 7694-7701 IN denotes without
T3600 7702-7709 JJ denotes primary
T3601 7710-7720 NN denotes antibodies
T3602 7721-7727 VB denotes served
T3603 7728-7730 IN denotes as
T3604 7731-7739 JJ denotes negative
T3605 7740-7748 NN denotes controls
T3744 7751-7754 CD denotes 2.5
T3745 7756-7763 JJ denotes Western
T3746 7764-7769 NN denotes Blots
T3747 7770-7778 JJ denotes Cellular
T3748 7779-7787 NN denotes proteins
T3749 7788-7792 VB denotes were
T3750 7793-7801 VB denotes prepared
T3751 7802-7806 IN denotes from
T3752 7807-7810 NN denotes ICH
T3753 7811-7819 JJ denotes cerebral
T3754 7820-7831 NN denotes hemispheres
T3755 7831-7832 -COMMA- denotes ,
T3756 7833-7848 VB denotes electrophoresed
T3757 7849-7853 IN denotes with
T3758 7854-7872 NN denotes SDS-polyacrylamide
T3759 7873-7876 NN denotes gel
T3760 7877-7880 CC denotes and
T3761 7881-7892 VB denotes transferred
T3762 7893-7897 IN denotes onto
T3763 7898-7904 NNP denotes Hybond
T3764 7905-7908 NN denotes ECL
T3765 7909-7918 NN denotes membranes
T3766 7919-7920 -LRB- denotes (
T3767 7920-7928 NNP denotes Amersham
T3768 7929-7938 NNP denotes Pharmacia
T3769 7938-7939 -COMMA- denotes ,
T3770 7940-7950 NNP denotes Piscataway
T3771 7950-7951 -COMMA- denotes ,
T3772 7952-7954 NNP denotes NJ
T3773 7954-7955 -RRB- denotes )
T3774 7957-7960 DT denotes The
T3775 7961-7964 NN denotes ECL
T3776 7965-7974 NN denotes membranes
T3777 7975-7979 VB denotes were
T3778 7980-7989 VB denotes incubated
T3779 7990-7994 IN denotes with
T3780 7995-7998 DT denotes the
T3781 7999-8010 JJ denotes appropriate
T3782 8011-8018 JJ denotes primary
T3783 8019-8027 NN denotes antibody
T3784 8028-8029 -LRB- denotes (
T3785 8029-8034 NN denotes WuHan
T3786 8034-8035 -COMMA- denotes ,
T3787 8036-8042 NN denotes BA1717
T3788 8042-8043 -RRB- denotes )
T3789 8044-8052 VB denotes followed
T3790 8053-8055 IN denotes by
T3791 8056-8066 NN denotes incubation
T3792 8067-8071 IN denotes with
T3793 8072-8093 JJ denotes peroxidase-conjugated
T3794 8094-8103 JJ denotes secondary
T3795 8104-8114 NN denotes antibodies
T3796 8115-8116 -LRB- denotes (
T3797 8116-8122 NNP denotes Golden
T3798 8123-8129 NNP denotes Bridge
T3799 8129-8130 -COMMA- denotes ,
T3800 8131-8138 NN denotes PV-6001
T3801 8138-8139 -RRB- denotes )
T3802 8141-8144 DT denotes The
T3803 8145-8152 NN denotes signals
T3804 8153-8157 VB denotes were
T3805 8158-8166 VB denotes detected
T3806 8167-8171 IN denotes with
T3807 8172-8175 DT denotes the
T3808 8176-8179 NN denotes ECL
T3809 8180-8186 NN denotes system
T3810 8187-8188 -LRB- denotes (
T3811 8188-8196 NNP denotes Amersham
T3812 8197-8206 NNP denotes Pharmacia
T3813 8206-8207 -RRB- denotes )
T3814 8209-8212 DT denotes The
T3815 8213-8217 JJ denotes same
T3816 8218-8227 NN denotes membranes
T3817 8228-8232 VB denotes were
T3818 8233-8239 VB denotes probed
T3819 8240-8244 IN denotes with
T3820 8245-8255 NN denotes anti-GAPDH
T3821 8256-8257 -LRB- denotes (
T3822 8257-8283 NN denotes glyceraldehyde-3-phosphate
T3823 8284-8297 NN denotes dehydrogenase
T3824 8297-8298 -COMMA- denotes ,
T3825 8299-8308 NNP denotes Biodesign
T3826 8308-8309 -COMMA- denotes ,
T3827 8310-8314 NNP denotes Saco
T3828 8314-8315 -COMMA- denotes ,
T3829 8316-8321 NNP denotes Maine
T3830 8321-8322 -RRB- denotes )
T3831 8323-8328 IN denotes after
T3832 8329-8334 VB denotes being
T3833 8335-8341 VB denotes washed
T3834 8342-8346 IN denotes with
T3835 8347-8356 VB denotes stripping
T3836 8357-8363 NN denotes buffer
T3837 8365-8368 DT denotes The
T3838 8369-8376 NN denotes signals
T3839 8377-8381 VB denotes were
T3840 8382-8392 VB denotes quantified
T3841 8393-8395 IN denotes by
T3842 8396-8404 VB denotes scanning
T3843 8405-8417 NN denotes densitometry
T3844 8418-8421 CC denotes and
T3845 8422-8439 JJ denotes computer-assisted
T3846 8440-8445 NN denotes image
T3847 8446-8454 NN denotes analysis
T4034 8457-8460 CD denotes 2.6
T4035 8462-8477 JJ denotes Electrophoretic
T4036 8478-8486 NN denotes Mobility
T4037 8487-8492 NN denotes Shift
T4038 8493-8498 NN denotes Assay
T4039 8499-8500 -LRB- denotes (
T4040 8500-8504 NN denotes EMSA
T4041 8504-8505 -RRB- denotes )
T4042 8506-8513 JJ denotes Nuclear
T4043 8514-8522 NN denotes proteins
T4044 8523-8527 VB denotes were
T4045 8528-8536 VB denotes isolated
T4046 8537-8541 IN denotes from
T4047 8542-8547 NN denotes brain
T4048 8548-8554 NN denotes tissue
T4049 8556-8563 RB denotes Briefly
T4050 8563-8564 -COMMA- denotes ,
T4051 8565-8570 IN denotes after
T4052 8571-8578 NN denotes removal
T4053 8579-8581 IN denotes of
T4054 8582-8593 NN denotes supernatant
T4055 8594-8595 -LRB- denotes (
T4056 8595-8606 JJ denotes cytoplasmic
T4057 8607-8614 NN denotes extract
T4058 8614-8615 -RRB- denotes )
T4059 8615-8616 -COMMA- denotes ,
T4060 8617-8620 DT denotes the
T4061 8621-8628 NN denotes pellets
T4062 8629-8633 VB denotes were
T4063 8634-8645 VB denotes resuspended
T4064 8646-8648 IN denotes in
T4065 8649-8656 JJ denotes nuclear
T4066 8657-8667 NN denotes extraction
T4067 8668-8675 NN denotes reagent
T4068 8677-8680 DT denotes The
T4069 8681-8686 NN denotes tubes
T4070 8687-8697 VB denotes containing
T4071 8698-8705 NN denotes pellets
T4072 8706-8710 VB denotes were
T4073 8711-8714 VB denotes put
T4074 8715-8717 IN denotes on
T4075 8718-8724 NN denotes vortex
T4076 8725-8728 IN denotes for
T4077 8729-8731 CD denotes 15
T4078 8732-8739 NN denotes seconds
T4079 8740-8745 DT denotes every
T4080 8746-8748 CD denotes 10
T4081 8749-8756 NN denotes minutes
T4082 8756-8757 -COMMA- denotes ,
T4083 8758-8761 IN denotes for
T4084 8762-8763 DT denotes a
T4085 8764-8769 NN denotes total
T4086 8770-8772 IN denotes of
T4087 8773-8775 CD denotes 40
T4088 8776-8783 NN denotes minutes
T4089 8785-8788 DT denotes The
T4090 8789-8794 NN denotes tubes
T4091 8795-8799 VB denotes were
T4092 8800-8811 VB denotes centrifuged
T4093 8812-8814 IN denotes at
T4094 8815-8822 JJ denotes maximum
T4095 8823-8828 NN denotes speed
T4096 8829-8830 -LRB- denotes (
T4097 8830-8837 CD denotes ~16,000
T4098 8838-8841 NN denotes × g
T4099 8841-8842 -RRB- denotes )
T4100 8843-8845 IN denotes in
T4101 8846-8847 DT denotes a
T4102 8848-8853 NN denotes micro
T4103 8854-8864 NN denotes centrifuge
T4104 8865-8868 IN denotes for
T4105 8869-8871 CD denotes 10
T4106 8872-8879 NN denotes minutes
T4107 8881-8884 DT denotes The
T4108 8885-8897 NN denotes supernatants
T4109 8898-8899 -LRB- denotes (
T4110 8899-8906 JJ denotes nuclear
T4111 8907-8914 NN denotes extract
T4112 8914-8915 -RRB- denotes )
T4113 8916-8920 VB denotes were
T4114 8921-8932 VB denotes transferred
T4115 8933-8935 TO denotes to
T4116 8936-8937 DT denotes a
T4117 8938-8943 JJ denotes clean
T4118 8944-8954 JJ denotes prechilled
T4119 8955-8959 NN denotes tube
T4120 8960-8963 CC denotes and
T4121 8964-8970 VB denotes stored
T4122 8971-8973 IN denotes at
T4123 8974-8979 NN denotes −80°C
T4124 8980-8985 IN denotes until
T4125 8986-8989 NN denotes use
T4126 8991-8995 NN denotes EMSA
T4127 8996-8999 VB denotes was
T4128 9000-9009 VB denotes performed
T4129 9010-9012 IN denotes as
T4130 9013-9022 VB denotes described
T4131 9023-9033 RB denotes previously
T4132 9034-9035 -LRB- denotes [
T4133 9035-9036 CD denotes 8
T4134 9036-9037 -RRB- denotes ]
T4135 9039-9043 NN denotes NFκB
T4136 9044-9051 NN denotes binding
T4137 9052-9060 NN denotes activity
T4138 9061-9064 VB denotes was
T4139 9065-9073 VB denotes examined
T4140 9074-9076 IN denotes in
T4141 9077-9078 DT denotes a
T4142 9079-9084 NN denotes 15 μL
T4143 9085-9092 NN denotes binding
T4144 9093-9101 NN denotes reaction
T4145 9102-9109 NN denotes mixture
T4146 9110-9120 VB denotes containing
T4147 9121-9126 NN denotes 15 μg
T4148 9127-9129 IN denotes of
T4149 9130-9137 JJ denotes nuclear
T4150 9138-9146 NN denotes proteins
T4151 9147-9150 CC denotes and
T4152 9151-9158 NN denotes 35 fmol
T4153 9159-9160 -LRB- denotes [
T4154 9160-9165 NN denotes γ-32P
T4155 9165-9166 -RRB- denotes ]
T4156 9167-9174 VB denotes labeled
T4157 9175-9190 JJ denotes double-stranded
T4158 9191-9195 NN denotes NFκB
T4159 9196-9205 NN denotes consensus
T4160 9206-9221 NN denotes oligonucleotide
T4161 9223-9224 DT denotes A
T4162 9225-9230 JJ denotes super
T4163 9231-9236 NN denotes shift
T4164 9237-9242 NN denotes assay
T4165 9243-9248 VB denotes using
T4166 9249-9259 NN denotes antibodies
T4167 9260-9262 TO denotes to
T4168 9263-9266 NN denotes P65
T4169 9267-9270 CC denotes and
T4170 9271-9274 NN denotes P50
T4171 9275-9278 VB denotes was
T4172 9279-9288 VB denotes performed
T4173 9289-9291 TO denotes to
T4174 9292-9299 VB denotes confirm
T4175 9300-9304 NN denotes NFκB
T4176 9305-9312 NN denotes binding
T4177 9313-9324 NN denotes specificity
T4178 9325-9327 IN denotes as
T4179 9328-9338 RB denotes previously
T4180 9339-9348 VB denotes described
T4385 9351-9354 CD denotes 2.7
T4386 9356-9367 JJ denotes Statistical
T4387 9368-9376 NN denotes Analysis
T4388 9377-9380 DT denotes All
T4389 9381-9385 NN denotes data
T4390 9386-9390 VB denotes were
T4391 9391-9400 VB denotes presented
T4392 9401-9403 IN denotes as
T4393 9404-9408 JJ denotes mean
T4394 9409-9410 NN denotes ±
T4395 9411-9414 NN denotes SEM
T4396 9416-9419 DT denotes The
T4397 9420-9432 NN denotes measurements
T4398 9433-9437 VB denotes were
T4399 9438-9446 VB denotes analyzed
T4400 9447-9449 IN denotes by
T4401 9450-9457 JJ denotes one-way
T4402 9458-9466 NN denotes analysis
T4403 9467-9469 IN denotes of
T4404 9470-9478 NN denotes variance
T4405 9479-9480 -LRB- denotes (
T4406 9480-9485 NN denotes ANOVA
T4407 9485-9486 -RRB- denotes )
T4408 9487-9489 CC denotes or
T4409 9490-9497 NN denotes Student
T4410 9497-9499 POS denotes 's
T4411 9500-9506 NN denotes t-test
T4412 9508-9511 DT denotes The
T4413 9512-9513 NN denotes P
T4414 9514-9515 JJ denotes <
T4415 9516-9519 CD denotes .05
T4416 9520-9525 NN denotes level
T4417 9526-9528 IN denotes of
T4418 9529-9540 NN denotes probability
T4419 9541-9544 VB denotes was
T4420 9545-9549 VB denotes used
T4421 9550-9552 IN denotes as
T4422 9553-9556 DT denotes the
T4423 9557-9565 NN denotes criteria
T4424 9566-9568 IN denotes of
T4425 9569-9581 NN denotes significance
T4543 9596-9599 CD denotes 3.1
T4544 9601-9605 NN denotes TLR4
T4545 9606-9610 NN denotes mRNA
T4546 9611-9620 VB denotes Increased
T4547 9621-9623 IN denotes in
T4548 9624-9629 NNP denotes Brain
T4549 9630-9636 NN denotes Tissue
T4550 9637-9642 IN denotes after
T4551 9643-9646 NN denotes ICH
T4552 9647-9651 NN denotes TLR4
T4553 9652-9656 NN denotes mRNA
T4554 9657-9663 NN denotes levels
T4555 9664-9668 VB denotes were
T4556 9669-9677 VB denotes detected
T4557 9678-9680 IN denotes by
T4558 9681-9687 NN denotes Rt-PCR
T4559 9689-9692 DT denotes The
T4560 9693-9696 JJ denotes low
T4561 9697-9702 NN denotes level
T4562 9703-9705 IN denotes of
T4563 9706-9710 NN denotes TLR4
T4564 9711-9715 NN denotes mRNA
T4565 9716-9719 VB denotes was
T4566 9720-9728 VB denotes observed
T4567 9729-9731 IN denotes in
T4568 9732-9738 JJ denotes normal
T4569 9739-9742 NN denotes rat
T4570 9743-9748 NN denotes brain
T4571 9749-9755 NN denotes tissue
T4572 9757-9759 IN denotes In
T4573 9760-9763 DT denotes the
T4574 9764-9770 NN denotes saline
T4575 9771-9778 NN denotes control
T4576 9779-9784 NN denotes group
T4577 9784-9785 -COMMA- denotes ,
T4578 9786-9789 DT denotes the
T4579 9790-9794 NN denotes TLR4
T4580 9795-9799 NN denotes mRNA
T4581 9800-9808 RB denotes slightly
T4582 9809-9818 VB denotes increased
T4583 9818-9819 -COMMA- denotes ,
T4584 9820-9823 CC denotes but
T4585 9824-9827 VB denotes was
T4586 9828-9831 RB denotes not
T4587 9832-9845 RB denotes significantly
T4588 9846-9855 JJ denotes different
T4589 9856-9860 IN denotes from
T4590 9861-9867 JJ denotes normal
T4591 9868-9873 NN denotes group
T4592 9875-9882 RB denotes However
T4593 9882-9883 -COMMA- denotes ,
T4594 9884-9887 DT denotes the
T4595 9888-9892 NN denotes TLR4
T4596 9893-9897 NN denotes mRNA
T4597 9898-9903 IN denotes after
T4598 9904-9907 NN denotes ICH
T4599 9908-9921 RB denotes significantly
T4600 9922-9931 VB denotes increased
T4601 9932-9940 VB denotes starting
T4602 9941-9945 IN denotes from
T4603 9946-9953 NN denotes 6 hours
T4604 9954-9959 IN denotes after
T4605 9960-9963 NN denotes ICH
T4606 9964-9965 -LRB- denotes (
T4607 9965-9966 NN denotes P
T4608 9967-9968 SYM denotes <
T4609 9969-9972 CD denotes .05
T4610 9972-9973 -RRB- denotes )
T4611 9973-9974 -COMMA- denotes ,
T4612 9975-9981 VB denotes peaked
T4613 9982-9984 IN denotes on
T4614 9985-9988 DT denotes the
T4615 9989-9992 JJ denotes 3rd
T4616 9993-9996 NN denotes day
T4617 9997-10002 IN denotes after
T4618 10003-10006 NN denotes ICH
T4619 10006-10007 -COMMA- denotes ,
T4620 10008-10011 CC denotes and
T4621 10012-10016 RB denotes then
T4622 10017-10026 VB denotes decreased
T4623 10027-10029 IN denotes on
T4624 10030-10033 DT denotes the
T4625 10034-10037 JJ denotes 7th
T4626 10038-10041 NN denotes day
T4627 10042-10047 IN denotes after
T4628 10048-10051 NN denotes ICH
T4629 10052-10053 -LRB- denotes (
T4630 10053-10054 NN denotes P
T4631 10055-10056 SYM denotes <
T4632 10057-10060 CD denotes .05
T4633 10060-10061 -RRB- denotes )
T4634 10061-10062 -COMMA- denotes ,
T4635 10063-10066 CC denotes but
T4636 10067-10072 RB denotes still
T4637 10073-10083 VB denotes maintained
T4638 10084-10085 DT denotes a
T4639 10086-10092 JJ denotes higher
T4640 10093-10098 NN denotes level
T4641 10099-10107 VB denotes compared
T4642 10108-10112 IN denotes with
T4643 10113-10119 NN denotes saline
T4644 10120-10127 NN denotes control
T4645 10128-10129 -LRB- denotes (
T4646 10129-10130 NN denotes P
T4647 10131-10132 JJ denotes <
T4648 10133-10136 CD denotes .05
T4649 10136-10137 -COMMA- denotes ,
T4650 10138-10144 NNP denotes Figure
T4651 10145-10146 CD denotes 1
T4652 10146-10147 -RRB- denotes )
T4958 10150-10153 CD denotes 3.2
T4959 10155-10165 NN denotes Expression
T4960 10166-10168 IN denotes of
T4961 10169-10173 NN denotes TLR4
T4962 10174-10181 NN denotes Protein
T4963 10182-10191 VB denotes Increased
T4964 10192-10194 IN denotes in
T4965 10195-10200 NNP denotes Brain
T4966 10201-10207 NN denotes Tissue
T4967 10208-10213 IN denotes after
T4968 10214-10217 NN denotes ICH
T4969 10218-10220 TO denotes To
T4970 10221-10232 VB denotes investigate
T4971 10233-10236 DT denotes the
T4972 10237-10246 VB denotes increased
T4973 10247-10251 NN denotes TLR4
T4974 10252-10254 IN denotes at
T4975 10255-10258 DT denotes the
T4976 10259-10266 NN denotes protein
T4977 10267-10272 NN denotes level
T4978 10272-10273 -COMMA- denotes ,
T4979 10274-10277 DT denotes the
T4980 10278-10288 NN denotes expression
T4981 10289-10291 IN denotes of
T4982 10292-10296 NN denotes TLR4
T4983 10297-10304 NN denotes protein
T4984 10305-10308 VB denotes was
T4985 10309-10317 VB denotes measured
T4986 10318-10320 IN denotes in
T4987 10321-10326 NN denotes brain
T4988 10327-10333 NN denotes tissue
T4989 10334-10336 IN denotes by
T4990 10337-10340 DT denotes the
T4991 10341-10347 NN denotes method
T4992 10348-10350 IN denotes of
T4993 10351-10358 JJ denotes Western
T4994 10359-10364 NN denotes Blots
T4995 10365-10370 VB denotes using
T4996 10371-10379 JJ denotes specific
T4997 10380-10390 NN denotes antibodies
T4998 10391-10394 IN denotes for
T4999 10395-10399 NN denotes TLR4
T5000 10401-10404 PRP-DOLLAR- denotes Our
T5001 10405-10412 NN denotes results
T5002 10413-10419 VB denotes showed
T5003 10420-10424 IN denotes that
T5004 10425-10426 DT denotes a
T5005 10427-10430 JJ denotes low
T5006 10431-10436 NN denotes level
T5007 10437-10439 IN denotes of
T5008 10440-10444 NN denotes TLR4
T5009 10445-10452 NN denotes protein
T5010 10453-10456 VB denotes was
T5011 10457-10467 JJ denotes detectable
T5012 10468-10470 IN denotes in
T5013 10471-10474 DT denotes the
T5014 10475-10481 NN denotes saline
T5015 10482-10489 NN denotes control
T5016 10490-10495 NN denotes group
T5017 10497-10500 DT denotes The
T5018 10501-10511 NN denotes expression
T5019 10512-10514 IN denotes of
T5020 10515-10519 NN denotes TLR4
T5021 10520-10533 RB denotes significantly
T5022 10534-10543 VB denotes increased
T5023 10544-10552 VB denotes starting
T5024 10553-10557 IN denotes from
T5025 10558-10565 NN denotes 6 hours
T5026 10566-10571 IN denotes after
T5027 10572-10575 NN denotes ICH
T5028 10576-10577 -LRB- denotes (
T5029 10577-10578 NN denotes P
T5030 10579-10580 SYM denotes <
T5031 10581-10584 CD denotes .05
T5032 10584-10585 -RRB- denotes )
T5033 10585-10586 -COMMA- denotes ,
T5034 10587-10593 VB denotes peaked
T5035 10594-10596 IN denotes on
T5036 10597-10600 DT denotes the
T5037 10601-10604 JJ denotes 3rd
T5038 10605-10608 NN denotes day
T5039 10609-10614 IN denotes after
T5040 10615-10618 NN denotes ICH
T5041 10618-10619 -COMMA- denotes ,
T5042 10620-10623 CC denotes and
T5043 10624-10628 RB denotes then
T5044 10629-10638 VB denotes decreased
T5045 10639-10642 CC denotes but
T5046 10643-10648 RB denotes still
T5047 10649-10659 VB denotes maintained
T5048 10660-10662 IN denotes at
T5049 10663-10664 DT denotes a
T5050 10665-10669 JJ denotes high
T5051 10670-10675 NN denotes level
T5052 10676-10678 IN denotes on
T5053 10679-10682 DT denotes the
T5054 10683-10686 JJ denotes 7th
T5055 10687-10690 NN denotes day
T5056 10691-10696 IN denotes after
T5057 10697-10700 NN denotes ICH
T5058 10701-10702 -LRB- denotes (
T5059 10702-10703 NN denotes P
T5060 10704-10705 JJ denotes <
T5061 10706-10709 CD denotes .05
T5062 10709-10710 -COMMA- denotes ,
T5063 10711-10717 NN denotes Figure
T5064 10718-10719 CD denotes 2
T5065 10719-10720 -RRB- denotes )
T5066 10722-10726 DT denotes This
T5067 10727-10738 NN denotes observation
T5068 10739-10741 IN denotes of
T5069 10742-10746 NN denotes TLR4
T5070 10747-10754 NN denotes protein
T5071 10755-10758 VB denotes was
T5072 10759-10769 JJ denotes consistent
T5073 10770-10774 IN denotes with
T5074 10775-10778 DT denotes the
T5075 10779-10787 JJ denotes temporal
T5076 10788-10795 NN denotes profile
T5077 10796-10798 IN denotes of
T5078 10799-10802 DT denotes the
T5079 10803-10807 NN denotes TLR4
T5080 10808-10812 NN denotes mRNA
T5081 10813-10818 IN denotes after
T5082 10819-10822 NN denotes ICH
T5391 10825-10828 CD denotes 3.3
T5392 10830-10842 NN denotes Distribution
T5393 10843-10845 IN denotes of
T5394 10846-10850 NN denotes TLR4
T5395 10851-10853 IN denotes in
T5396 10854-10859 NNP denotes Brain
T5397 10860-10869 NNP denotes Subjected
T5398 10870-10872 TO denotes to
T5399 10873-10876 VB denotes ICH
T5400 10877-10879 TO denotes To
T5401 10880-10887 VB denotes explore
T5402 10888-10891 DT denotes the
T5403 10892-10904 NN denotes distribution
T5404 10905-10907 IN denotes of
T5405 10908-10912 NN denotes TLR4
T5406 10913-10920 NN denotes protein
T5407 10920-10921 -COMMA- denotes ,
T5408 10922-10925 DT denotes the
T5409 10926-10930 NN denotes TLR4
T5410 10931-10934 VB denotes was
T5411 10935-10943 VB denotes detected
T5412 10944-10946 IN denotes by
T5413 10947-10967 NN denotes immunohistochemistry
T5414 10968-10969 -LRB- denotes (
T5415 10969-10972 NN denotes IHC
T5416 10972-10973 -RRB- denotes )
T5417 10975-10982 NN denotes Results
T5418 10983-10989 VB denotes showed
T5419 10990-10994 IN denotes that
T5420 10995-10999 NN denotes TLR4
T5421 11000-11016 NN denotes immunoreactivity
T5422 11017-11020 VB denotes was
T5423 11021-11024 RB denotes not
T5424 11025-11035 JJ denotes detectable
T5425 11036-11038 IN denotes in
T5426 11039-11044 NN denotes brain
T5427 11045-11051 NN denotes tissue
T5428 11052-11056 IN denotes from
T5429 11057-11063 JJ denotes normal
T5430 11064-11067 CC denotes and
T5431 11068-11072 NN denotes sham
T5432 11073-11080 NN denotes control
T5433 11082-11089 RB denotes However
T5434 11089-11090 -COMMA- denotes ,
T5435 11091-11107 NN denotes immunoreactivity
T5436 11108-11111 IN denotes for
T5437 11112-11116 NN denotes TLR4
T5438 11117-11120 VB denotes was
T5439 11121-11133 RB denotes consistently
T5440 11134-11146 VB denotes demonstrated
T5441 11147-11149 IN denotes in
T5442 11150-11165 JJ denotes peri-hemorrhage
T5443 11166-11171 NN denotes areas
T5444 11171-11172 -COMMA- denotes ,
T5445 11173-11176 DT denotes the
T5446 11177-11188 NN denotes hippocampus
T5447 11188-11189 -COMMA- denotes ,
T5448 11190-11196 NN denotes cortex
T5449 11196-11197 -COMMA- denotes ,
T5450 11198-11206 JJ denotes thalamic
T5451 11207-11213 NN denotes nuclei
T5452 11213-11214 -COMMA- denotes ,
T5453 11215-11218 CC denotes and
T5454 11219-11223 DT denotes some
T5455 11224-11229 JJ denotes white
T5456 11230-11236 NN denotes matter
T5457 11237-11243 NN denotes tracts
T5458 11244-11245 -LRB- denotes (
T5459 11245-11251 NN denotes Figure
T5460 11252-11253 CD denotes 3
T5461 11253-11254 -RRB- denotes )
T5665 11257-11260 CD denotes 3.4
T5666 11262-11272 NN denotes Activation
T5667 11273-11275 IN denotes of
T5668 11276-11289 JJ denotes TLR4-Mediated
T5669 11290-11300 NN denotes NF-Kappa-B
T5670 11301-11310 NN denotes Signaling
T5671 11311-11321 NN denotes Activation
T5672 11322-11324 IN denotes of
T5673 11325-11329 NN denotes TLR4
T5674 11330-11337 VB denotes induces
T5675 11338-11341 DT denotes the
T5676 11342-11357 NN denotes phosphorylation
T5677 11358-11360 IN denotes of
T5678 11361-11370 NN denotes inhibitor
T5679 11371-11373 IN denotes of
T5680 11374-11381 NN denotes kappa-B
T5681 11382-11383 -LRB- denotes (
T5682 11383-11386 NN denotes IκB
T5683 11386-11387 -RRB- denotes )
T5684 11387-11388 -COMMA- denotes ,
T5685 11389-11394 WDT denotes which
T5686 11395-11406 VB denotes dissociates
T5687 11407-11410 NN denotes IκB
T5688 11411-11415 IN denotes with
T5689 11416-11426 NN denotes NF-kappa-B
T5690 11427-11428 -LRB- denotes (
T5691 11428-11432 NN denotes NFκB
T5692 11432-11433 -RRB- denotes )
T5693 11435-11439 RB denotes Then
T5694 11439-11440 -COMMA- denotes ,
T5695 11441-11445 NN denotes NFκB
T5696 11446-11458 VB denotes translocates
T5697 11459-11463 IN denotes into
T5698 11464-11467 DT denotes the
T5699 11468-11475 NN denotes nucleus
T5700 11476-11479 CC denotes and
T5701 11480-11489 VB denotes activates
T5702 11490-11493 CC denotes and
T5703 11494-11503 VB denotes regulates
T5704 11504-11507 DT denotes the
T5705 11508-11521 NN denotes transcription
T5706 11522-11524 IN denotes of
T5707 11525-11530 NN denotes genes
T5708 11531-11538 VB denotes related
T5709 11539-11541 TO denotes to
T5710 11542-11554 JJ denotes inflammatory
T5711 11555-11564 NN denotes responses
T5712 11566-11568 TO denotes To
T5713 11569-11576 VB denotes detectd
T5714 11577-11580 DT denotes the
T5715 11581-11591 NN denotes activation
T5716 11592-11594 IN denotes of
T5717 11595-11608 JJ denotes TLR4-mediated
T5718 11609-11613 NN denotes NFκB
T5719 11614-11623 NN denotes signaling
T5720 11623-11624 -COMMA- denotes ,
T5721 11625-11628 DT denotes the
T5722 11629-11644 NN denotes phosphorylation
T5723 11645-11647 IN denotes of
T5724 11648-11657 NN denotes inhibitor
T5725 11658-11660 IN denotes of
T5726 11661-11668 NN denotes kappa-B
T5727 11669-11670 -LRB- denotes (
T5728 11670-11675 NN denotes p-IκB
T5729 11675-11676 -RRB- denotes )
T5730 11677-11680 CC denotes and
T5731 11681-11689 NN denotes activity
T5732 11690-11692 IN denotes of
T5733 11693-11697 NN denotes NFκB
T5734 11698-11702 VB denotes were
T5735 11703-11711 VB denotes measured
T5736 11712-11714 IN denotes by
T5737 11715-11722 NN denotes methods
T5738 11723-11725 IN denotes of
T5739 11726-11733 JJ denotes Western
T5740 11734-11739 NN denotes Blots
T5741 11740-11743 CC denotes and
T5742 11744-11748 NN denotes EMSA
T5743 11750-11757 NN denotes Results
T5744 11758-11764 VB denotes showed
T5745 11765-11769 IN denotes that
T5746 11770-11773 DT denotes the
T5747 11774-11779 NN denotes p-IκB
T5748 11780-11789 VB denotes increased
T5749 11790-11792 IN denotes at
T5750 11793-11800 NN denotes 6 hours
T5751 11801-11806 IN denotes after
T5752 11807-11810 NN denotes ICH
T5753 11811-11812 -LRB- denotes (
T5754 11812-11813 NN denotes P
T5755 11814-11815 SYM denotes <
T5756 11816-11819 CD denotes .05
T5757 11819-11820 -RRB- denotes )
T5758 11820-11821 -COMMA- denotes ,
T5759 11822-11828 VB denotes peaked
T5760 11829-11831 IN denotes on
T5761 11832-11833 CD denotes 3
T5762 11834-11838 NN denotes days
T5763 11839-11844 IN denotes after
T5764 11845-11848 NN denotes ICH
T5765 11848-11849 -COMMA- denotes ,
T5766 11850-11853 CC denotes and
T5767 11854-11864 VB denotes maintained
T5768 11865-11866 DT denotes a
T5769 11867-11871 JJ denotes high
T5770 11872-11877 NN denotes level
T5771 11878-11880 IN denotes on
T5772 11881-11882 CD denotes 7
T5773 11883-11887 NN denotes days
T5774 11888-11893 IN denotes after
T5775 11894-11897 NN denotes ICH
T5776 11898-11899 -LRB- denotes (
T5777 11899-11900 NN denotes P
T5778 11901-11902 JJ denotes <
T5779 11903-11906 CD denotes .05
T5780 11906-11907 -COMMA- denotes ,
T5781 11908-11914 NNP denotes Figure
T5782 11915-11916 CD denotes 5
T5783 11916-11917 -RRB- denotes )
T5784 11919-11921 IN denotes As
T5785 11922-11930 VB denotes expected
T5786 11930-11931 -COMMA- denotes ,
T5787 11932-11935 DT denotes the
T5788 11936-11944 NN denotes activity
T5789 11945-11947 IN denotes of
T5790 11948-11952 NN denotes NFκB
T5791 11953-11956 VB denotes was
T5792 11957-11961 RB denotes also
T5793 11962-11971 VB denotes increased
T5794 11972-11974 IN denotes in
T5795 11975-11978 DT denotes the
T5796 11979-11983 JJ denotes same
T5797 11984-11990 NN denotes manner
T5798 11991-11993 IN denotes as
T5799 11994-11998 DT denotes that
T5800 11999-12001 IN denotes of
T5801 12002-12005 DT denotes the
T5802 12006-12011 NN denotes p-IκB
T5803 12012-12013 -LRB- denotes (
T5804 12013-12019 NN denotes Figure
T5805 12020-12021 CD denotes 4
T5806 12021-12022 -RRB- denotes )
T6547 12039-12053 JJ denotes Intra-cerebral
T6548 12054-12064 NN denotes hemorrhage
T6549 12065-12066 -LRB- denotes (
T6550 12066-12069 NN denotes ICH
T6551 12069-12070 -RRB- denotes )
T6552 12071-12081 VB denotes represents
T6553 12082-12087 CD denotes 10–15
T6554 12087-12088 NN denotes %
T6555 12089-12091 IN denotes of
T6556 12092-12095 DT denotes all
T6557 12096-12103 NN denotes strokes
T6558 12103-12104 -COMMA- denotes ,
T6559 12105-12108 CC denotes and
T6560 12109-12115 VB denotes occurs
T6561 12116-12120 IN denotes with
T6562 12121-12131 VB denotes increasing
T6563 12132-12141 NN denotes frequency
T6564 12142-12144 IN denotes as
T6565 12145-12146 DT denotes a
T6566 12147-12159 NN denotes complication
T6567 12160-12162 IN denotes of
T6568 12163-12166 DT denotes the
T6569 12167-12179 JJ denotes thrombolytic
T6570 12180-12189 NN denotes treatment
T6571 12190-12192 IN denotes of
T6572 12193-12201 JJ denotes ischemic
T6573 12202-12208 NN denotes stroke
T6574 12209-12210 -LRB- denotes [
T6575 12210-12211 CD denotes 1
T6576 12211-12212 -RRB- denotes ]
T6577 12214-12217 DT denotes The
T6578 12218-12227 NN denotes mortality
T6579 12228-12230 IN denotes of
T6580 12231-12234 NN denotes ICH
T6581 12235-12237 VB denotes is
T6582 12238-12244 JJ denotes higher
T6583 12245-12249 IN denotes than
T6584 12250-12254 DT denotes that
T6585 12255-12257 IN denotes of
T6586 12258-12266 JJ denotes ischemic
T6587 12267-12273 NN denotes stroke
T6588 12275-12279 RB denotes Only
T6589 12280-12282 CD denotes 31
T6590 12282-12283 NN denotes %
T6591 12284-12287 VB denotes are
T6592 12288-12300 RB denotes functionally
T6593 12301-12312 JJ denotes independent
T6594 12313-12315 IN denotes at
T6595 12316-12317 CD denotes 3
T6596 12318-12324 NN denotes months
T6597 12326-12330 RB denotes Only
T6598 12331-12333 CD denotes 38
T6599 12333-12334 NN denotes %
T6600 12335-12337 IN denotes of
T6601 12338-12341 DT denotes the
T6602 12342-12350 NN denotes patients
T6603 12351-12358 VB denotes survive
T6604 12359-12362 DT denotes the
T6605 12363-12366 JJ denotes 1st
T6606 12367-12371 NN denotes year
T6607 12372-12373 -LRB- denotes [
T6608 12373-12375 CD denotes 10
T6609 12375-12376 -RRB- denotes ]
T6610 12378-12391 RB denotes Unfortunately
T6611 12391-12392 -COMMA- denotes ,
T6612 12393-12396 DT denotes the
T6613 12397-12403 NN denotes method
T6614 12404-12407 IN denotes for
T6615 12408-12417 NN denotes treatment
T6616 12418-12420 IN denotes of
T6617 12421-12425 DT denotes this
T6618 12426-12433 NN denotes disease
T6619 12434-12437 CC denotes and
T6620 12438-12448 NN denotes protection
T6621 12449-12451 IN denotes of
T6622 12452-12455 DT denotes the
T6623 12456-12461 NN denotes brain
T6624 12462-12468 NN denotes tissue
T6625 12469-12474 IN denotes after
T6626 12475-12478 NN denotes ICH
T6627 12479-12482 VB denotes are
T6628 12483-12486 RB denotes not
T6629 12487-12496 JJ denotes effective
T6630 12498-12502 NNP denotes Mass
T6631 12503-12509 NN denotes effect
T6632 12509-12510 -COMMA- denotes ,
T6633 12511-12519 NN denotes ischemia
T6634 12519-12520 -COMMA- denotes ,
T6635 12521-12524 CC denotes and
T6636 12525-12533 NN denotes toxicity
T6637 12534-12536 IN denotes of
T6638 12537-12542 NN denotes blood
T6639 12543-12553 NN denotes components
T6640 12554-12559 IN denotes after
T6641 12560-12563 NN denotes ICH
T6642 12564-12570 VB denotes induce
T6643 12571-12576 NN denotes brain
T6644 12577-12583 NN denotes tissue
T6645 12584-12590 NN denotes damage
T6646 12592-12594 IN denotes In
T6647 12595-12603 NN denotes addition
T6648 12603-12604 -COMMA- denotes ,
T6649 12605-12610 EX denotes there
T6650 12611-12613 VB denotes is
T6651 12614-12624 VB denotes increasing
T6652 12625-12633 NN denotes evidence
T6653 12634-12638 IN denotes that
T6654 12639-12651 JJ denotes inflammatory
T6655 12652-12661 NN denotes processes
T6656 12662-12665 VB denotes are
T6657 12666-12674 VB denotes involved
T6658 12675-12677 IN denotes in
T6659 12678-12693 JJ denotes cerebrovascular
T6660 12694-12700 NN denotes events
T6661 12702-12707 IN denotes After
T6662 12708-12711 NN denotes ICH
T6663 12711-12712 -COMMA- denotes ,
T6664 12713-12725 JJ denotes inflammatory
T6665 12726-12735 NN denotes mediators
T6666 12736-12740 IN denotes from
T6667 12741-12744 DT denotes the
T6668 12745-12750 NN denotes blood
T6669 12751-12756 MD denotes might
T6670 12757-12762 VB denotes enter
T6671 12763-12765 TO denotes to
T6672 12766-12769 DT denotes the
T6673 12770-12775 NN denotes brain
T6674 12776-12779 CC denotes and
T6675 12780-12786 VB denotes induce
T6676 12787-12789 DT denotes an
T6677 12790-12802 JJ denotes inflammatory
T6678 12803-12811 NN denotes reaction
T6679 12812-12815 CC denotes and
T6680 12816-12819 DT denotes the
T6681 12820-12825 NN denotes brain
T6682 12826-12831 NN denotes cells
T6683 12832-12838 PRP denotes itself
T6684 12839-12842 VB denotes are
T6685 12843-12847 RB denotes also
T6686 12848-12855 JJ denotes capable
T6687 12856-12858 IN denotes of
T6688 12859-12868 VB denotes producing
T6689 12869-12873 JJ denotes many
T6690 12874-12876 IN denotes of
T6691 12877-12882 DT denotes these
T6692 12883-12889 NN denotes agents
T6693 12890-12891 -LRB- denotes [
T6694 12891-12893 CD denotes 11
T6695 12893-12894 -RRB- denotes ]
T6696 12896-12899 DT denotes The
T6697 12900-12912 JJ denotes inflammatory
T6698 12913-12922 NN denotes responses
T6699 12923-12926 VB denotes are
T6700 12927-12938 JJ denotes responsible
T6701 12939-12942 IN denotes for
T6702 12943-12946 DT denotes the
T6703 12947-12950 NN denotes ICH
T6704 12951-12958 VB denotes induced
T6705 12959-12964 NN denotes brain
T6706 12965-12971 NN denotes injury
T6707 12971-12972 -COMMA- denotes ,
T6708 12973-12978 WDT denotes which
T6709 12979-12984 MD denotes could
T6710 12985-12992 VB denotes provide
T6711 12993-12996 JJ denotes new
T6712 12997-13008 JJ denotes therapeutic
T6713 13009-13016 NN denotes targets
T6714 13017-13020 IN denotes for
T6715 13021-13024 NN denotes ICH
T6716 13026-13033 JJ denotes Various
T6717 13034-13046 NN denotes constituents
T6718 13047-13049 IN denotes of
T6719 13050-13053 DT denotes the
T6720 13054-13066 JJ denotes inflammatory
T6721 13067-13075 NN denotes response
T6722 13075-13076 -COMMA- denotes ,
T6723 13077-13086 VB denotes including
T6724 13087-13095 NN denotes adhesion
T6725 13096-13105 NN denotes molecules
T6726 13105-13106 -COMMA- denotes ,
T6727 13107-13116 NN denotes cytokines
T6728 13116-13117 -COMMA- denotes ,
T6729 13118-13128 NN denotes leukocytes
T6730 13128-13129 -COMMA- denotes ,
T6731 13130-13145 NN denotes immunoglobulins
T6732 13145-13146 -COMMA- denotes ,
T6733 13147-13150 CC denotes and
T6734 13151-13161 NN denotes complement
T6735 13161-13162 -COMMA- denotes ,
T6736 13163-13166 MD denotes may
T6737 13167-13169 VB denotes be
T6738 13170-13179 JJ denotes important
T6739 13180-13182 IN denotes in
T6740 13183-13186 DT denotes the
T6741 13187-13199 NN denotes pathogenesis
T6742 13200-13202 IN denotes of
T6743 13203-13206 NN denotes ICH
T6744 13208-13215 RB denotes However
T6745 13215-13216 -COMMA- denotes ,
T6746 13217-13220 WRB denotes how
T6747 13221-13224 DT denotes the
T6748 13225-13237 JJ denotes inflammatory
T6749 13238-13247 NN denotes responses
T6750 13248-13250 VB denotes is
T6751 13251-13260 VB denotes activated
T6752 13261-13264 CC denotes and
T6753 13265-13274 VB denotes regulated
T6754 13275-13277 IN denotes in
T6755 13278-13281 DT denotes the
T6756 13282-13287 NN denotes brain
T6757 13288-13294 NN denotes tissue
T6758 13295-13300 IN denotes after
T6759 13301-13304 NN denotes ICH
T6760 13305-13307 VB denotes is
T6761 13308-13315 JJ denotes unclear
T6762 13317-13330 NN denotes Transcription
T6763 13331-13337 NN denotes factor
T6764 13338-13345 JJ denotes nuclear
T6765 13346-13360 NN denotes factor-kappa-B
T6766 13361-13362 -LRB- denotes (
T6767 13362-13366 NN denotes NFκB
T6768 13366-13367 -RRB- denotes )
T6769 13368-13370 VB denotes is
T6770 13371-13373 DT denotes an
T6771 13374-13383 JJ denotes important
T6772 13384-13391 JJ denotes nuclear
T6773 13392-13405 NN denotes transcription
T6774 13406-13412 NN denotes factor
T6775 13412-13413 -COMMA- denotes ,
T6776 13414-13419 WDT denotes which
T6777 13420-13429 VB denotes initiates
T6778 13430-13443 NN denotes transcription
T6779 13444-13446 IN denotes of
T6780 13447-13452 NN denotes genes
T6781 13453-13463 VB denotes associated
T6782 13464-13468 IN denotes with
T6783 13469-13475 JJ denotes immune
T6784 13476-13485 NN denotes responses
T6785 13486-13489 CC denotes and
T6786 13490-13502 NN denotes inflammation
T6787 13503-13504 -LRB- denotes [
T6788 13504-13506 CD denotes 12
T6789 13506-13507 -COMMA- denotes ,
T6790 13508-13510 CD denotes 13
T6791 13510-13511 -RRB- denotes ]
T6792 13512-13515 CC denotes and
T6793 13516-13520 RB denotes also
T6794 13521-13526 VB denotes plays
T6795 13527-13528 DT denotes a
T6796 13529-13532 JJ denotes key
T6797 13533-13537 NN denotes role
T6798 13538-13540 IN denotes in
T6799 13541-13551 VB denotes regulating
T6800 13552-13564 NN denotes inflammation
T6801 13565-13567 IN denotes in
T6802 13568-13573 NN denotes brain
T6803 13574-13585 NN denotes pathologies
T6804 13587-13589 PRP denotes It
T6805 13590-13593 VB denotes has
T6806 13594-13598 VB denotes been
T6807 13599-13607 VB denotes reported
T6808 13608-13612 IN denotes that
T6809 13613-13617 NN denotes NFκB
T6810 13618-13627 VB denotes increased
T6811 13628-13630 IN denotes in
T6812 13631-13634 DT denotes the
T6813 13635-13641 NN denotes region
T6814 13642-13644 IN denotes of
T6815 13645-13657 NN denotes perihematoma
T6816 13658-13663 IN denotes after
T6817 13664-13667 NN denotes ICH
T6818 13668-13669 -LRB- denotes [
T6819 13669-13671 CD denotes 14
T6820 13671-13672 -RRB- denotes ]
T6821 13674-13678 NN denotes NFκB
T6822 13679-13689 NN denotes activation
T6823 13690-13696 VB denotes occurs
T6824 13697-13703 IN denotes within
T6825 13704-13711 NN denotes minutes
T6826 13712-13715 CC denotes and
T6827 13716-13724 VB denotes persists
T6828 13725-13728 IN denotes for
T6829 13729-13731 IN denotes at
T6830 13732-13737 JJ denotes least
T6831 13738-13739 DT denotes a
T6832 13740-13744 NN denotes week
T6833 13745-13747 IN denotes in
T6834 13748-13756 NN denotes response
T6835 13757-13759 TO denotes to
T6836 13760-13763 NN denotes ICH
T6837 13763-13764 -COMMA- denotes ,
T6838 13765-13770 WDT denotes which
T6839 13771-13773 VB denotes is
T6840 13774-13784 VB denotes associated
T6841 13785-13789 IN denotes with
T6842 13790-13793 DT denotes the
T6843 13794-13804 NN denotes expression
T6844 13805-13807 IN denotes of
T6845 13808-13816 VB denotes selected
T6846 13817-13823 NN denotes target
T6847 13824-13829 NN denotes genes
T6848 13830-13831 -LRB- denotes [
T6849 13831-13833 CD denotes 15
T6850 13833-13834 -RRB- denotes ]
T6851 13836-13846 NN denotes Activation
T6852 13847-13849 IN denotes of
T6853 13850-13854 NN denotes NFκB
T6854 13855-13864 VB denotes initiates
T6855 13865-13877 JJ denotes inflammatory
T6856 13878-13887 NN denotes responses
T6857 13888-13891 CC denotes and
T6858 13892-13903 VB denotes contributes
T6859 13904-13906 TO denotes to
T6860 13907-13910 DT denotes the
T6861 13911-13923 NN denotes pathobiology
T6862 13924-13926 IN denotes of
T6863 13927-13939 JJ denotes perilesional
T6864 13940-13944 NN denotes cell
T6865 13945-13950 NN denotes death
T6866 13951-13956 IN denotes after
T6867 13957-13960 NN denotes ICH
T6868 13961-13962 -LRB- denotes [
T6869 13962-13964 CD denotes 16
T6870 13964-13965 -RRB- denotes ]
T6871 13967-13977 NN denotes Inhibition
T6872 13978-13980 IN denotes of
T6873 13981-13985 NN denotes NFκB
T6874 13986-13994 NN denotes activity
T6875 13995-13998 VB denotes has
T6876 13999-14003 VB denotes been
T6877 14004-14009 VB denotes shown
T6878 14010-14012 TO denotes to
T6879 14013-14017 VB denotes have
T6880 14018-14019 DT denotes a
T6881 14020-14031 JJ denotes therapeutic
T6882 14032-14038 NN denotes effect
T6883 14039-14041 IN denotes on
T6884 14042-14054 JJ denotes experimental
T6885 14055-14058 NN denotes ICH
T6886 14058-14059 -COMMA- denotes ,
T6887 14060-14064 JJ denotes such
T6888 14065-14067 IN denotes as
T6889 14068-14074 NN denotes reduce
T6890 14075-14087 NN denotes inflammation
T6891 14087-14088 -COMMA- denotes ,
T6892 14089-14099 JJ denotes behavioral
T6893 14100-14111 NN denotes dysfunction
T6894 14111-14112 -COMMA- denotes ,
T6895 14113-14116 CC denotes and
T6896 14117-14125 JJ denotes neuronal
T6897 14126-14132 NN denotes damage
T6898 14133-14141 VB denotes produced
T6899 14142-14144 IN denotes by
T6900 14145-14148 NN denotes ICH
T6901 14149-14150 -LRB- denotes [
T6902 14150-14152 CD denotes 17
T6903 14152-14153 -RRB- denotes ]
T6904 14155-14158 DT denotes The
T6905 14159-14168 NN denotes knowledge
T6906 14169-14174 IN denotes about
T6907 14175-14178 WRB denotes how
T6908 14179-14183 NN denotes NFκB
T6909 14184-14186 VB denotes is
T6910 14187-14196 VB denotes activated
T6911 14197-14199 IN denotes in
T6912 14200-14203 DT denotes the
T6913 14204-14209 NN denotes brain
T6914 14210-14219 VB denotes subjected
T6915 14220-14222 TO denotes to
T6916 14223-14226 NN denotes ICH
T6917 14227-14229 VB denotes is
T6918 14230-14238 JJ denotes critical
T6919 14239-14242 IN denotes for
T6920 14243-14250 VB denotes seeking
T6921 14251-14252 DT denotes a
T6922 14253-14256 JJ denotes new
T6923 14257-14272 JJ denotes neuroprotective
T6924 14273-14279 NN denotes method
T6925 14280-14283 IN denotes for
T6926 14284-14287 NN denotes ICH
T6927 14289-14298 JJ denotes Toll-like
T6928 14299-14308 NN denotes receptors
T6929 14309-14310 -LRB- denotes (
T6930 14310-14314 NN denotes TLRs
T6931 14314-14315 -RRB- denotes )
T6932 14316-14319 VB denotes are
T6933 14320-14321 DT denotes a
T6934 14322-14328 NN denotes family
T6935 14329-14331 IN denotes of
T6936 14332-14338 NN denotes signal
T6937 14339-14351 NN denotes transduction
T6938 14352-14361 NN denotes molecules
T6939 14362-14365 CC denotes and
T6940 14366-14370 VB denotes play
T6941 14371-14372 DT denotes a
T6942 14373-14381 JJ denotes critical
T6943 14382-14386 NN denotes role
T6944 14387-14389 IN denotes in
T6945 14390-14393 DT denotes the
T6946 14394-14403 NN denotes induction
T6947 14404-14406 IN denotes of
T6948 14407-14413 JJ denotes innate
T6949 14414-14417 CC denotes and
T6950 14418-14426 JJ denotes adaptive
T6951 14427-14435 NN denotes immunity
T6952 14436-14437 -LRB- denotes [
T6953 14437-14438 CD denotes 4
T6954 14438-14439 -RRB- denotes ]
T6955 14441-14453 JJ denotes TLR-mediated
T6956 14454-14463 NN denotes signaling
T6957 14464-14472 NN denotes pathways
T6958 14473-14479 RB denotes mainly
T6959 14480-14489 VB denotes stimulate
T6960 14490-14493 DT denotes the
T6961 14494-14504 NN denotes activation
T6962 14505-14507 IN denotes of
T6963 14508-14512 NN denotes NFκB
T6964 14513-14514 -LRB- denotes [
T6965 14514-14516 CD denotes 12
T6966 14516-14517 -COMMA- denotes ,
T6967 14518-14520 CD denotes 13
T6968 14520-14521 -RRB- denotes ]
T6969 14523-14527 NN denotes TLR4
T6970 14527-14528 -COMMA- denotes ,
T6971 14529-14532 DT denotes the
T6972 14533-14538 JJ denotes first
T6973 14539-14548 JJ denotes mammalian
T6974 14549-14552 NN denotes TLR
T6975 14553-14563 VB denotes recognized
T6976 14563-14564 -COMMA- denotes ,
T6977 14565-14568 VB denotes has
T6978 14569-14573 VB denotes been
T6979 14574-14582 VB denotes reported
T6980 14583-14585 TO denotes to
T6981 14586-14588 VB denotes be
T6982 14589-14597 VB denotes involved
T6983 14598-14600 IN denotes in
T6984 14601-14608 JJ denotes several
T6985 14609-14616 JJ denotes central
T6986 14617-14624 JJ denotes nervous
T6987 14625-14626 -LRB- denotes (
T6988 14626-14629 NN denotes CNS
T6989 14629-14630 -RRB- denotes )
T6990 14631-14637 NN denotes system
T6991 14638-14646 NN denotes diseases
T6992 14646-14647 -COMMA- denotes ,
T6993 14648-14652 JJ denotes such
T6994 14653-14655 IN denotes as
T6995 14656-14668 JJ denotes inflammatory
T6996 14669-14671 CC denotes or
T6997 14672-14682 JJ denotes autoimmune
T6998 14683-14686 NN denotes CNS
T6999 14687-14695 NN denotes diseases
T7000 14696-14699 CC denotes and
T7001 14700-14708 JJ denotes cerebral
T7002 14709-14717 JJ denotes ischemic
T7003 14718-14724 NN denotes injury
T7004 14725-14726 -LRB- denotes [
T7005 14726-14727 CD denotes 7
T7006 14727-14728 -COMMA- denotes ,
T7007 14729-14730 CD denotes 8
T7008 14730-14731 -RRB- denotes ]
T7009 14733-14741 IN denotes Although
T7010 14742-14750 JJ denotes previous
T7011 14751-14758 NN denotes reports
T7012 14759-14768 VB denotes indicated
T7013 14769-14773 IN denotes that
T7014 14774-14777 DT denotes the
T7015 14778-14788 NN denotes activation
T7016 14789-14791 IN denotes of
T7017 14792-14796 NN denotes NFκB
T7018 14797-14800 VB denotes was
T7019 14801-14811 VB denotes attributed
T7020 14812-14814 TO denotes to
T7021 14815-14818 DT denotes the
T7022 14819-14828 JJ denotes oxidative
T7023 14829-14835 NN denotes stress
T7024 14836-14838 CC denotes or
T7025 14839-14848 NN denotes glutamate
T7026 14849-14857 NN denotes receptor
T7027 14858-14868 NN denotes activation
T7028 14869-14876 VB denotes induced
T7029 14877-14879 IN denotes by
T7030 14880-14883 JJ denotes red
T7031 14884-14889 NN denotes blood
T7032 14890-14895 NN denotes cells
T7033 14896-14902 CC denotes and/or
T7034 14903-14909 NN denotes plasma
T7035 14910-14922 NN denotes constituents
T7036 14923-14924 -LRB- denotes [
T7037 14924-14926 CD denotes 17
T7038 14926-14927 -RRB- denotes ]
T7039 14927-14928 -COMMA- denotes ,
T7040 14929-14933 RB denotes very
T7041 14934-14937 JJ denotes few
T7042 14938-14945 NN denotes studies
T7043 14946-14950 VB denotes have
T7044 14951-14955 VB denotes been
T7045 14956-14964 VB denotes directed
T7046 14965-14967 TO denotes to
T7047 14968-14979 VB denotes investigate
T7048 14980-14983 DT denotes the
T7049 14984-14988 NN denotes role
T7050 14989-14992 CC denotes and
T7051 14993-14996 DT denotes the
T7052 14997-15009 NN denotes relationship
T7053 15010-15017 IN denotes between
T7054 15018-15031 JJ denotes TLR4-mediated
T7055 15032-15036 NN denotes NFκB
T7056 15037-15046 NN denotes signaling
T7057 15047-15050 CC denotes and
T7058 15051-15054 NN denotes ICH
T7059 15056-15058 IN denotes In
T7060 15059-15062 DT denotes the
T7061 15063-15070 JJ denotes present
T7062 15071-15076 NN denotes study
T7063 15076-15077 -COMMA- denotes ,
T7064 15078-15080 PRP denotes we
T7065 15081-15092 VB denotes established
T7066 15093-15096 DT denotes the
T7067 15097-15100 NN denotes rat
T7068 15101-15106 NN denotes model
T7069 15107-15109 IN denotes of
T7070 15110-15122 JJ denotes experimental
T7071 15123-15126 NN denotes ICH
T7072 15127-15130 CC denotes and
T7073 15131-15139 VB denotes detected
T7074 15140-15143 DT denotes the
T7075 15144-15148 NN denotes TLR4
T7076 15149-15153 NN denotes mRNA
T7077 15154-15157 CC denotes and
T7078 15158-15165 NN denotes protein
T7079 15167-15170 PRP-DOLLAR- denotes Our
T7080 15171-15175 NN denotes data
T7081 15176-15182 VB denotes showed
T7082 15183-15187 IN denotes that
T7083 15188-15201 NN denotes transcription
T7084 15202-15204 IN denotes of
T7085 15205-15209 NN denotes TLR4
T7086 15210-15212 RB denotes as
T7087 15213-15217 RB denotes well
T7088 15218-15220 IN denotes as
T7089 15221-15224 DT denotes the
T7090 15225-15235 NN denotes expression
T7091 15236-15238 IN denotes of
T7092 15239-15243 NN denotes TLR4
T7093 15244-15251 NN denotes protein
T7094 15252-15257 IN denotes after
T7095 15258-15261 NN denotes ICH
T7096 15262-15275 RB denotes significantly
T7097 15276-15284 JJ denotes elevated
T7098 15285-15287 IN denotes in
T7099 15288-15293 NN denotes brain
T7100 15294-15300 NN denotes tissue
T7101 15302-15307 DT denotes These
T7102 15308-15315 NN denotes changes
T7103 15316-15323 VB denotes started
T7104 15324-15326 RB denotes as
T7105 15327-15332 RB denotes early
T7106 15333-15335 IN denotes as
T7107 15336-15337 CD denotes 6
T7108 15338-15343 NN denotes hours
T7109 15344-15349 IN denotes after
T7110 15350-15353 DT denotes the
T7111 15354-15357 NN denotes ICH
T7112 15358-15364 NN denotes insult
T7113 15365-15368 CC denotes and
T7114 15369-15379 VB denotes maintained
T7115 15380-15382 IN denotes at
T7116 15383-15384 DT denotes a
T7117 15385-15389 JJ denotes high
T7118 15390-15395 NN denotes level
T7119 15396-15399 IN denotes for
T7120 15400-15401 CD denotes 7
T7121 15402-15406 NN denotes days
T7122 15407-15416 RB denotes afterward
T7123 15418-15421 DT denotes The
T7124 15422-15426 NN denotes TLR4
T7125 15427-15434 NN denotes protein
T7126 15434-15435 -COMMA- denotes ,
T7127 15436-15444 VB denotes detected
T7128 15445-15447 IN denotes by
T7129 15448-15468 NN denotes immunohistochemistry
T7130 15468-15469 -COMMA- denotes ,
T7131 15470-15473 VB denotes was
T7132 15474-15486 RB denotes consistently
T7133 15487-15498 VB denotes distributed
T7134 15499-15501 IN denotes in
T7135 15502-15517 JJ denotes peri-hemorrhage
T7136 15518-15523 NN denotes areas
T7137 15523-15524 -COMMA- denotes ,
T7138 15525-15528 DT denotes the
T7139 15529-15540 NN denotes hippocampus
T7140 15540-15541 -COMMA- denotes ,
T7141 15542-15548 NN denotes cortex
T7142 15548-15549 -COMMA- denotes ,
T7143 15550-15558 JJ denotes thalamic
T7144 15559-15565 NN denotes nuclei
T7145 15565-15566 -COMMA- denotes ,
T7146 15567-15570 CC denotes and
T7147 15571-15575 DT denotes some
T7148 15576-15581 JJ denotes white
T7149 15582-15588 NN denotes matter
T7150 15589-15595 NN denotes tracts
T7151 15597-15602 DT denotes These
T7152 15603-15607 NN denotes data
T7153 15608-15617 VB denotes indicated
T7154 15618-15622 IN denotes that
T7155 15623-15632 VB denotes increased
T7156 15633-15643 NN denotes expression
T7157 15644-15646 IN denotes of
T7158 15647-15651 NN denotes TLR4
T7159 15652-15655 MD denotes may
T7160 15656-15658 VB denotes be
T7161 15659-15666 JJ denotes related
T7162 15667-15669 TO denotes to
T7163 15670-15673 DT denotes the
T7164 15674-15684 NN denotes triggering
T7165 15685-15687 IN denotes of
T7166 15688-15691 DT denotes the
T7167 15692-15704 JJ denotes inflammatory
T7168 15705-15714 NN denotes responses
T7169 15715-15717 IN denotes in
T7170 15718-15721 DT denotes the
T7171 15722-15727 NN denotes brain
T7172 15728-15734 NN denotes tissue
T7173 15735-15740 IN denotes after
T7174 15741-15744 NN denotes ICH
T7175 15746-15752 JJ denotes Recent
T7176 15753-15760 NN denotes studies
T7177 15761-15773 VB denotes demonstrated
T7178 15774-15778 IN denotes that
T7179 15779-15782 NN denotes ICH
T7180 15783-15792 VB denotes initiates
T7181 15793-15805 JJ denotes inflammatory
T7182 15806-15815 NN denotes responses
T7183 15815-15816 -COMMA- denotes ,
T7184 15817-15822 WDT denotes which
T7185 15823-15826 VB denotes are
T7186 15827-15837 VB denotes associated
T7187 15838-15842 IN denotes with
T7188 15843-15852 JJ denotes secondary
T7189 15853-15859 NN denotes growth
T7190 15860-15862 IN denotes of
T7191 15863-15873 NN denotes hemorrhage
T7192 15874-15877 CC denotes and
T7193 15878-15882 NN denotes cell
T7194 15883-15888 NN denotes death
T7195 15889-15890 -LRB- denotes [
T7196 15890-15892 CD denotes 18
T7197 15892-15893 -RRB- denotes ]
T7198 15895-15897 PRP denotes It
T7199 15898-15900 VB denotes is
T7200 15901-15904 RB denotes now
T7201 15905-15913 VB denotes believed
T7202 15914-15918 IN denotes that
T7203 15919-15937 NN denotes TLR4-mediated-NFκB
T7204 15938-15945 NN denotes pathway
T7205 15946-15955 VB denotes activates
T7206 15956-15959 CC denotes and
T7207 15960-15969 VB denotes regulates
T7208 15970-15983 JJ denotes immunological
T7209 15984-15987 CC denotes and
T7210 15988-16000 JJ denotes inflammatory
T7211 16001-16010 NN denotes responses
T7212 16012-16014 TO denotes To
T7213 16015-16026 VB denotes investigate
T7214 16027-16030 DT denotes the
T7215 16031-16041 NN denotes mechanisms
T7216 16042-16052 VB denotes underlying
T7217 16053-16056 DT denotes the
T7218 16057-16066 VB denotes increased
T7219 16067-16079 JJ denotes inflammatory
T7220 16080-16089 NN denotes responses
T7221 16090-16092 IN denotes in
T7222 16093-16096 DT denotes the
T7223 16097-16102 NN denotes brain
T7224 16103-16108 IN denotes after
T7225 16109-16112 NN denotes ICH
T7226 16112-16113 -COMMA- denotes ,
T7227 16114-16116 IN denotes in
T7228 16117-16120 DT denotes the
T7229 16121-16128 JJ denotes present
T7230 16129-16134 NN denotes study
T7231 16134-16135 -COMMA- denotes ,
T7232 16136-16138 PRP denotes we
T7233 16139-16148 VB denotes evaluated
T7234 16149-16152 DT denotes the
T7235 16153-16163 NN denotes activation
T7236 16164-16166 IN denotes of
T7237 16167-16180 JJ denotes TLR4-mediated
T7238 16181-16185 NN denotes NFκB
T7239 16186-16195 NN denotes signaling
T7240 16196-16198 IN denotes by
T7241 16199-16208 VB denotes detecting
T7242 16209-16212 DT denotes the
T7243 16213-16218 NN denotes p-IκB
T7244 16219-16222 CC denotes and
T7245 16223-16226 DT denotes the
T7246 16227-16235 NN denotes activity
T7247 16236-16238 IN denotes of
T7248 16239-16243 NN denotes NFκB
T7249 16244-16246 IN denotes in
T7250 16247-16258 JJ denotes hemorrhagic
T7251 16259-16265 NN denotes brains
T7252 16267-16271 NN denotes NFκB
T7253 16272-16274 VB denotes is
T7254 16275-16277 DT denotes an
T7255 16278-16287 JJ denotes important
T7256 16288-16301 NN denotes transcription
T7257 16302-16308 NN denotes factor
T7258 16309-16319 RB denotes downstream
T7259 16320-16322 IN denotes in
T7260 16323-16326 DT denotes the
T7261 16327-16340 JJ denotes TLR4-mediated
T7262 16341-16350 NN denotes signaling
T7263 16351-16358 NN denotes pathway
T7264 16360-16370 NN denotes Activation
T7265 16371-16373 IN denotes of
T7266 16374-16378 NN denotes TLR4
T7267 16379-16389 VB denotes stimulates
T7268 16390-16394 NN denotes IκBα
T7269 16395-16410 NN denotes phosphorylation
T7270 16411-16414 CC denotes and
T7271 16415-16426 NN denotes degradation
T7272 16426-16427 -COMMA- denotes ,
T7273 16428-16437 VB denotes resulting
T7274 16438-16440 IN denotes in
T7275 16441-16448 JJ denotes nuclear
T7276 16449-16462 NN denotes translocation
T7277 16463-16465 IN denotes of
T7278 16466-16470 NN denotes NFκB
T7279 16470-16471 -COMMA- denotes ,
T7280 16472-16477 WDT denotes which
T7281 16478-16487 VB denotes initiates
T7282 16488-16501 NN denotes transcription
T7283 16502-16504 IN denotes of
T7284 16505-16510 NN denotes genes
T7285 16511-16521 VB denotes associated
T7286 16522-16526 IN denotes with
T7287 16527-16533 JJ denotes innate
T7288 16534-16540 JJ denotes immune
T7289 16541-16550 NN denotes responses
T7290 16551-16554 CC denotes and
T7291 16555-16567 NN denotes inflammation
T7292 16568-16569 -LRB- denotes [
T7293 16569-16570 CD denotes 5
T7294 16570-16571 -COMMA- denotes ,
T7295 16572-16573 CD denotes 6
T7296 16573-16574 -RRB- denotes ]
T7297 16576-16578 PRP denotes We
T7298 16579-16587 VB denotes observed
T7299 16588-16592 IN denotes that
T7300 16593-16596 DT denotes the
T7301 16597-16603 NN denotes levels
T7302 16604-16606 IN denotes of
T7303 16607-16622 NN denotes phosphorylation
T7304 16623-16625 IN denotes of
T7305 16626-16629 NN denotes IκB
T7306 16630-16633 CC denotes and
T7307 16634-16637 DT denotes the
T7308 16638-16646 NN denotes activity
T7309 16647-16649 IN denotes of
T7310 16650-16654 NN denotes NFκB
T7311 16655-16659 VB denotes were
T7312 16660-16673 RB denotes significantly
T7313 16674-16683 VB denotes increased
T7314 16684-16686 IN denotes in
T7315 16687-16692 NN denotes brain
T7316 16693-16699 NN denotes tissue
T7317 16700-16705 IN denotes after
T7318 16706-16709 NN denotes ICH
T7319 16711-16714 DT denotes The
T7320 16715-16723 JJ denotes temporal
T7321 16724-16731 NN denotes profile
T7322 16732-16734 IN denotes of
T7323 16735-16738 DT denotes the
T7324 16739-16749 NN denotes expression
T7325 16750-16752 IN denotes of
T7326 16753-16758 NN denotes p-IκB
T7327 16759-16762 CC denotes and
T7328 16763-16766 DT denotes the
T7329 16767-16777 NN denotes activation
T7330 16778-16780 IN denotes of
T7331 16781-16785 NN denotes NFκB
T7332 16786-16789 VB denotes was
T7333 16790-16797 JJ denotes similar
T7334 16798-16800 TO denotes to
T7335 16801-16805 DT denotes that
T7336 16806-16808 IN denotes of
T7337 16809-16812 DT denotes the
T7338 16813-16823 NN denotes expression
T7339 16824-16826 IN denotes of
T7340 16827-16831 NN denotes TLR4
T7341 16833-16836 PRP-DOLLAR- denotes Our
T7342 16837-16841 NN denotes data
T7343 16842-16849 VB denotes suggest
T7344 16850-16854 IN denotes that
T7345 16855-16858 NN denotes ICH
T7346 16859-16869 VB denotes stimulates
T7347 16870-16880 NN denotes activation
T7348 16881-16883 IN denotes of
T7349 16884-16887 DT denotes the
T7350 16888-16897 NN denotes TLR4/NFκB
T7351 16898-16907 NN denotes signaling
T7352 16908-16915 NN denotes pathway
T7353 16915-16916 -COMMA- denotes ,
T7354 16917-16922 WDT denotes which
T7355 16923-16925 VB denotes is
T7356 16926-16936 JJ denotes consistent
T7357 16937-16941 IN denotes with
T7358 16942-16950 JJ denotes previous
T7359 16951-16958 NN denotes reports
T7360 16959-16963 IN denotes that
T7361 16964-16974 NN denotes activation
T7362 16975-16977 IN denotes of
T7363 16978-16982 NN denotes NFκB
T7364 16983-16985 VB denotes is
T7365 16986-16995 VB denotes regulated
T7366 16996-17003 IN denotes through
T7367 17004-17007 DT denotes the
T7368 17008-17021 JJ denotes TLR4-mediated
T7369 17022-17031 NN denotes signaling
T7370 17032-17039 NN denotes pathway
T7371 17041-17045 NN denotes TLR4
T7372 17046-17051 VB denotes plays
T7373 17052-17054 DT denotes an
T7374 17055-17064 JJ denotes important
T7375 17065-17069 NN denotes role
T7376 17070-17072 IN denotes in
T7377 17073-17076 DT denotes the
T7378 17077-17088 NN denotes recognition
T7379 17089-17091 IN denotes of
T7380 17092-17101 JJ denotes microbial
T7381 17102-17112 NN denotes components
T7382 17113-17114 -LRB- denotes [
T7383 17114-17116 CD denotes 19
T7384 17116-17117 -COMMA- denotes ,
T7385 17118-17120 CD denotes 20
T7386 17120-17121 -RRB- denotes ]
T7387 17122-17125 CC denotes and
T7388 17126-17129 MD denotes can
T7389 17130-17134 RB denotes also
T7390 17135-17144 VB denotes recognize
T7391 17145-17155 JJ denotes endogenous
T7392 17156-17165 NN denotes molecules
T7393 17166-17170 JJ denotes such
T7394 17171-17173 IN denotes as
T7395 17174-17177 DT denotes the
T7396 17178-17189 NN denotes degradation
T7397 17190-17198 NN denotes products
T7398 17199-17201 IN denotes of
T7399 17202-17216 NN denotes macromolecules
T7400 17216-17217 -COMMA- denotes ,
T7401 17218-17226 NN denotes products
T7402 17227-17229 IN denotes of
T7403 17230-17241 JJ denotes proteolytic
T7404 17242-17250 NN denotes cascades
T7405 17250-17251 -COMMA- denotes ,
T7406 17252-17265 JJ denotes intracellular
T7407 17266-17276 NN denotes components
T7408 17277-17279 IN denotes of
T7409 17280-17288 JJ denotes ruptured
T7410 17289-17294 NN denotes cells
T7411 17294-17295 -COMMA- denotes ,
T7412 17296-17299 CC denotes and
T7413 17300-17308 NN denotes products
T7414 17309-17311 IN denotes of
T7415 17312-17317 NN denotes genes
T7416 17318-17322 WDT denotes that
T7417 17323-17326 VB denotes are
T7418 17327-17336 VB denotes activated
T7419 17337-17339 IN denotes by
T7420 17340-17352 NN denotes inflammation
T7421 17354-17357 IN denotes For
T7422 17358-17366 NN denotes instance
T7423 17366-17367 -COMMA- denotes ,
T7424 17368-17373 NN denotes HSP70
T7425 17373-17374 -COMMA- denotes ,
T7426 17375-17380 NN denotes HSP32
T7427 17380-17381 -COMMA- denotes ,
T7428 17382-17387 NN denotes HSP27
T7429 17387-17388 -COMMA- denotes ,
T7430 17389-17392 CC denotes and
T7431 17393-17400 NN denotes enzymes
T7432 17401-17409 VB denotes involved
T7433 17410-17412 IN denotes in
T7434 17413-17422 JJ denotes oxidative
T7435 17423-17429 NN denotes stress
T7436 17430-17433 VB denotes are
T7437 17434-17439 VB denotes found
T7438 17440-17442 TO denotes to
T7439 17443-17445 VB denotes be
T7440 17446-17457 VB denotes upregulated
T7441 17458-17460 IN denotes in
T7442 17461-17464 DT denotes the
T7443 17465-17470 NN denotes brain
T7444 17471-17476 IN denotes after
T7445 17477-17480 NN denotes ICH
T7446 17480-17481 -COMMA- denotes ,
T7447 17482-17487 WDT denotes which
T7448 17488-17491 MD denotes may
T7449 17492-17494 VB denotes be
T7450 17495-17503 VB denotes produced
T7451 17504-17506 IN denotes by
T7452 17507-17514 VB denotes injured
T7453 17515-17523 JJ denotes neuronal
T7454 17524-17529 NN denotes cells
T7455 17530-17532 CC denotes or
T7456 17533-17538 NN denotes blood
T7457 17539-17544 NN denotes cells
T7458 17545-17546 -LRB- denotes [
T7459 17546-17548 CD denotes 21
T7460 17548-17549 -RRB- denotes ]
T7461 17551-17553 PRP denotes It
T7462 17554-17557 MD denotes may
T7463 17558-17560 VB denotes be
T7464 17561-17571 VB denotes speculated
T7465 17572-17576 IN denotes that
T7466 17577-17582 DT denotes these
T7467 17583-17592 NN denotes molecules
T7468 17593-17601 VB denotes produced
T7469 17602-17604 IN denotes in
T7470 17605-17612 VB denotes damaged
T7471 17613-17618 NN denotes brain
T7472 17619-17621 CC denotes or
T7473 17622-17626 VB denotes came
T7474 17627-17631 IN denotes from
T7475 17632-17637 NN denotes blood
T7476 17638-17643 NN denotes cells
T7477 17644-17647 CC denotes and
T7478 17648-17660 NN denotes constituents
T7479 17661-17663 IN denotes of
T7480 17664-17670 NN denotes plasma
T7481 17671-17677 NN denotes server
T7482 17678-17680 IN denotes as
T7483 17681-17691 JJ denotes endogenous
T7484 17692-17696 NN denotes TLR4
T7485 17697-17704 NN denotes ligands
T7486 17704-17705 -COMMA- denotes ,
T7487 17706-17714 VB denotes activate
T7488 17715-17728 JJ denotes TLR4-mediated
T7489 17729-17733 NN denotes NFκB
T7490 17734-17743 NN denotes signaling
T7491 17743-17744 -COMMA- denotes ,
T7492 17745-17748 CC denotes and
T7493 17749-17757 VB denotes initiate
T7494 17758-17761 DT denotes the
T7495 17762-17774 JJ denotes inflammatory
T7496 17775-17784 NN denotes responses
T7497 17785-17787 IN denotes in
T7498 17788-17791 NN denotes IHC
T7499 17792-17797 NN denotes brain
T7500 17799-17806 RB denotes However
T7501 17806-17807 -COMMA- denotes ,
T7502 17808-17811 DT denotes the
T7503 17812-17820 JJ denotes specific
T7504 17821-17831 JJ denotes endogenous
T7505 17832-17839 NN denotes ligands
T7506 17840-17843 IN denotes for
T7507 17844-17848 NN denotes TLR4
T7508 17849-17851 IN denotes in
T7509 17852-17863 JJ denotes hemorrhagic
T7510 17864-17869 NN denotes brain
T7511 17870-17874 VB denotes have
T7512 17875-17878 RB denotes not
T7513 17879-17883 VB denotes been
T7514 17884-17894 VB denotes determined
T7515 17895-17898 CC denotes and
T7516 17899-17903 VB denotes need
T7517 17904-17906 TO denotes to
T7518 17907-17909 VB denotes be
T7519 17910-17920 VB denotes identified
T7520 17921-17928 IN denotes through
T7521 17929-17936 JJ denotes further
T7522 17937-17945 NN denotes research
T7523 17947-17949 IN denotes In
T7524 17950-17960 NN denotes conclusion
T7525 17960-17961 -COMMA- denotes ,
T7526 17962-17965 DT denotes the
T7527 17966-17973 JJ denotes present
T7528 17974-17979 NN denotes study
T7529 17980-17992 VB denotes demonstrated
T7530 17993-17996 DT denotes the
T7531 17997-18005 JJ denotes temporal
T7532 18006-18013 NN denotes profile
T7533 18014-18016 IN denotes of
T7534 18017-18020 DT denotes the
T7535 18021-18031 NN denotes activation
T7536 18032-18034 IN denotes of
T7537 18035-18048 JJ denotes TLR4-mediated
T7538 18049-18053 NN denotes NFκB
T7539 18054-18063 NN denotes signaling
T7540 18064-18066 IN denotes in
T7541 18067-18072 NN denotes brain
T7542 18073-18079 NN denotes tissue
T7543 18080-18082 IN denotes in
T7544 18083-18084 DT denotes a
T7545 18085-18088 NN denotes rat
T7546 18089-18094 NN denotes model
T7547 18095-18097 IN denotes of
T7548 18098-18110 JJ denotes experimental
T7549 18111-18114 NN denotes ICH
T7550 18114-18115 -COMMA- denotes ,
T7551 18116-18121 WDT denotes which
T7552 18122-18130 VB denotes suggests
T7553 18131-18135 IN denotes that
T7554 18136-18149 JJ denotes TLR4-mediated
T7555 18150-18154 NN denotes NFκB
T7556 18155-18164 NN denotes signaling
T7557 18165-18177 VB denotes participates
T7558 18178-18180 IN denotes in
T7559 18181-18184 DT denotes the
T7560 18185-18197 NN denotes pathogenesis
T7561 18198-18200 IN denotes of
T7562 18201-18204 NN denotes ICH
T7563 18204-18205 -COMMA- denotes ,
T7564 18206-18211 WDT denotes which
T7565 18212-18215 MD denotes may
T7566 18216-18218 VB denotes be
T7567 18219-18220 DT denotes a
T7568 18221-18232 JJ denotes therapeutic
T7569 18233-18239 NN denotes target
T7570 18240-18243 IN denotes for
T7571 18244-18247 DT denotes the
T7572 18248-18258 NN denotes prevention
T7573 18259-18261 IN denotes of
T7574 18262-18273 JJ denotes ICH-induced
T7575 18274-18279 NN denotes brain
T7576 18280-18286 NN denotes damage
R100 T235 T233 arg2Of expression,of
R101 T235 T234 arg1Of expression,the
R102 T235 T236 arg1Of expression,of
R103 T237 T236 arg2Of TLR4,of
R104 T238 T229 arg2Of and,evaluate
R105 T240 T238 arg2Of activation,and
R106 T240 T239 arg1Of activation,the
R107 T240 T241 arg1Of activation,of
R108 T240 T245 arg1Of activation,in
R109 T244 T241 arg2Of signaling,of
R110 T244 T242 arg1Of signaling,TLR4-mediated
R111 T244 T243 arg1Of signaling,NFκB
R112 T247 T245 arg2Of tissues,in
R113 T247 T246 arg1Of tissues,brain
R114 T247 T248 arg1Of tissues,of
R115 T250 T248 arg2Of rats,of
R116 T250 T249 arg1Of rats,Wistar
R117 T250 T251 arg1Of rats,after
R118 T252 T251 arg2Of ICH,after
R119 T254 T255 arg1Of mRNA,and
R120 T255 T253 arg1Of and,TLR4
R121 T255 T257 arg1Of and,","
R122 T255 T269 arg1Of and,and
R123 T256 T255 arg2Of protein,and
R124 T259 T257 arg2Of phosphorylation,","
R125 T259 T258 arg1Of phosphorylation,the
R126 T259 T260 arg1Of phosphorylation,of
R127 T261 T260 arg2Of inhibitors,of
R128 T261 T262 arg1Of inhibitors,of
R129 T264 T262 arg2Of B,of
R130 T264 T263 arg1Of B,kappa
R131 T264 T265 arg1Of B,(
R132 T266 T265 arg2Of p-IκBα,(
R1324 T1779 T1778 arg1Of Wister,Ninety
R1325 T1780 T1779 arg1Of rats,Wister
R1326 T1780 T1781 arg1Of rats,(
R1327 T1782 T1781 arg2Of male,(
R1328 T1782 T1783 arg1Of male,","
R1329 T1785 T1783 arg2Of weight,","
R133 T267 T265 arg3Of ),(
R1330 T1785 T1784 arg1Of weight,body
R1331 T1786 T1781 arg3Of :,(
R1332 T1787 T1788 arg1Of 250 g,to
R1333 T1789 T1788 arg2Of 300 g,to
R1334 T1792 T1791 arg2Of provided,were
R1335 T1796 T1794 arg1Of Center,Experimental
R1336 T1796 T1795 arg1Of Center,Animal
R1337 T1796 T1797 arg1Of Center,","
R1338 T1799 T1797 arg2Of Medical,","
R1339 T1799 T1798 arg1Of Medical,China
R134 T269 T268 arg1Of and,","
R1340 T1800 T1792 arg1Of University.,provided
R1341 T1800 T1793 arg2Of University.,by
R1342 T1800 T1796 arg1Of University.,Center
R1343 T1800 T1799 arg1Of University.,Medical
R1344 T1802 T1801 arg1Of rats,The
R1345 T1802 T1803 arg1Of rats,were
R1346 T1802 T1804 arg2Of rats,assigned
R1347 T1804 T1803 arg2Of assigned,were
R1348 T1804 T1805 arg1Of assigned,randomly
R1349 T1804 T1806 arg1Of assigned,to
R135 T269 T274 arg1Of and,were
R1350 T1808 T1806 arg2Of groups,to
R1351 T1808 T1807 arg1Of groups,three
R1352 T1811 T1810 arg1Of group,normal
R1353 T1811 T1812 arg1Of group,(
R1354 T1811 T1823 arg1Of group,","
R1355 T1813 T1812 arg2Of N,(
R1356 T1813 T1814 arg1Of N,","
R1357 T1813 T1816 arg1Of N,=
R1358 T1813 T1819 arg1Of N,without
R1359 T1815 T1814 arg2Of n,","
R136 T269 T275 arg2Of and,examined
R1360 T1816 T1817 arg1Of =,10
R1361 T1816 T1818 arg1Of =,","
R1362 T1821 T1819 arg2Of treatment,without
R1363 T1821 T1820 arg1Of treatment,any
R1364 T1822 T1812 arg3Of ),(
R1365 T1823 T1809 arg2Of ",",:
R1366 T1826 T1823 arg2Of control,","
R1367 T1826 T1824 arg1Of control,normal
R1368 T1826 T1825 arg1Of control,saline
R1369 T1828 T1829 arg1Of S,","
R137 T271 T269 arg2Of activity,and
R1370 T1830 T1829 arg2Of n,","
R1371 T1832 T1831 arg1Of 40,=
R1372 T1832 T1833 arg1Of 40,","
R1373 T1834 T1833 arg2Of intra-cerebral,","
R1374 T1835 T1832 arg1Of injection,40
R1375 T1835 T1834 arg1Of injection,intra-cerebral
R1376 T1835 T1836 arg1Of injection,of
R1377 T1838 T1836 arg2Of saline,of
R1378 T1838 T1837 arg1Of saline,normal
R1379 T1840 T1839 arg2Of control,as
R138 T271 T270 arg1Of activity,the
R1380 T1845 T1842 arg2Of group,and
R1381 T1845 T1843 arg1Of group,intra-cerebral
R1382 T1845 T1844 arg1Of group,hemorrhage
R1383 T1845 T1846 arg1Of group,(
R1384 T1847 T1846 arg2Of ICH,(
R1385 T1847 T1848 arg1Of ICH,","
R1386 T1849 T1848 arg2Of n,","
R1387 T1849 T1850 arg1Of n,=
R1388 T1849 T1851 arg1Of n,40
R1389 T1852 T1846 arg3Of ),(
R139 T271 T272 arg1Of activity,of
R1390 T1855 T1853 arg1Of protocol,The
R1391 T1855 T1854 arg1Of protocol,experimental
R1392 T1855 T1856 arg2Of protocol,used
R1393 T1855 T1859 arg1Of protocol,was
R1394 T1855 T1860 arg2Of protocol,approved
R1395 T1856 T1857 arg1Of used,for
R1396 T1858 T1857 arg2Of animals,for
R1397 T1860 T1859 arg2Of approved,was
R1398 T1864 T1863 arg1Of Care,Animal
R1399 T1864 T1865 arg1Of Care,and
R140 T273 T272 arg2Of NFκB,of
R1400 T1865 T1860 arg1Of and,approved
R1401 T1865 T1861 arg2Of and,by
R1402 T1865 T1862 arg1Of and,the
R1403 T1867 T1865 arg2Of Committee,and
R1404 T1867 T1866 arg1Of Committee,Use
R1405 T1871 T1869 arg1Of University.,China
R1406 T1871 T1870 arg1Of University.,Medical
R1407 T1873 T1871 arg1Of rats,University.
R1408 T1873 T1872 arg1Of rats,The
R1409 T1873 T1874 arg1Of rats,were
R141 T275 T274 arg2Of examined,were
R1410 T1873 T1875 arg2Of rats,subjected
R1411 T1873 T1887 arg1Of rats,were
R1412 T1873 T1888 arg2Of rats,sacrificed
R1413 T1875 T1874 arg2Of subjected,were
R1414 T1875 T1876 arg1Of subjected,to
R1415 T1875 T1886 arg1Of subjected,and
R1416 T1878 T1876 arg2Of injection,to
R1417 T1878 T1877 arg1Of injection,intra-cerebral
R1418 T1878 T1879 arg1Of injection,of
R1419 T1881 T1880 arg1Of saline,normal
R142 T275 T276 arg1Of examined,in
R1420 T1881 T1882 arg1Of saline,or
R1421 T1882 T1879 arg2Of or,of
R1422 T1885 T1882 arg2Of blood,or
R1423 T1885 T1883 arg1Of blood,autologous
R1424 T1885 T1884 arg1Of blood,whole
R1425 T1886 T1859 modOf and,was
R1426 T1886 T1868 arg1Of and,","
R1427 T1888 T1886 arg2Of sacrificed,and
R1428 T1888 T1887 arg2Of sacrificed,were
R1429 T1888 T1889 arg1Of sacrificed,on
R143 T279 T276 arg2Of tissue,in
R1430 T1888 T1900 arg1Of sacrificed,after
R1431 T1888 T1903 arg1Of sacrificed,","
R1432 T1888 T1904 arg1Of sacrificed,respectively
R1433 T1890 T1891 arg1Of 6 hours,","
R1434 T1891 T1894 arg1Of ",",","
R1435 T1893 T1891 arg2Of day,","
R1436 T1893 T1892 arg1Of day,1
R1437 T1894 T1897 arg1Of ",",and
R1438 T1896 T1894 arg2Of days,","
R1439 T1896 T1895 arg1Of days,3
R144 T279 T277 arg1Of tissue,hemorrhagic
R1440 T1897 T1889 arg2Of and,on
R1441 T1899 T1897 arg2Of days,and
R1442 T1899 T1898 arg1Of days,7
R1443 T1902 T1900 arg2Of injection,after
R1444 T1902 T1901 arg1Of injection,the
R1445 T1906 T1905 arg1Of rats,Five
R1446 T1906 T1907 arg1Of rats,in
R1447 T1906 T1926 arg1Of rats,buffered
R1448 T1909 T1907 arg2Of group,in
R1449 T1909 T1908 arg1Of group,each
R145 T279 T278 arg1Of tissue,cerebral
R1450 T1909 T1910 arg1Of group,at
R1451 T1912 T1910 arg2Of time,at
R1452 T1912 T1911 arg1Of time,each
R1453 T1913 T1914 arg1Of point,were
R1454 T1913 T1915 arg2Of point,sacrificed
R1455 T1915 T1912 arg2Of sacrificed,time
R1456 T1915 T1914 arg2Of sacrificed,were
R1457 T1918 T1915 arg1Of perfusion,sacrificed
R1458 T1918 T1916 arg2Of perfusion,by
R1459 T1918 T1917 arg1Of perfusion,transcardially
R146 T281 T282 arg1Of Rt-PCR,","
R1460 T1918 T1919 arg1Of perfusion,of
R1461 T1921 T1919 arg2Of saline,of
R1462 T1921 T1920 arg1Of saline,normal
R1463 T1921 T1922 arg2Of saline,followed
R1464 T1922 T1923 arg1Of followed,by
R1465 T1925 T1923 arg2Of %,by
R1466 T1925 T1924 arg1Of %,4
R1467 T1928 T1926 arg2Of formaldehyde,buffered
R1468 T1928 T1927 arg1Of formaldehyde,Para
R1469 T1928 T1929 arg1Of formaldehyde,(
R147 T282 T285 arg1Of ",",","
R1470 T1930 T1929 arg2Of pH,(
R1471 T1930 T1931 arg1Of pH,=
R1472 T1930 T1932 arg1Of pH,7.4
R1473 T1933 T1929 arg3Of ),(
R1474 T1935 T1934 arg1Of brains,The
R1475 T1935 T1936 arg1Of brains,were
R1476 T1935 T1937 arg2Of brains,removed
R1477 T1935 T1939 arg2Of brains,postfixed
R1478 T1935 T1941 arg2Of brains,embedded
R1479 T1935 T1946 arg1Of brains,cut
R148 T284 T282 arg2Of blots,","
R1480 T1937 T1938 arg1Of removed,","
R1481 T1938 T1940 arg1Of ",",","
R1482 T1939 T1938 arg2Of postfixed,","
R1483 T1940 T1936 arg2Of ",",were
R1484 T1940 T1945 arg1Of ",",and
R1485 T1941 T1940 arg2Of embedded,","
R1486 T1941 T1942 arg1Of embedded,in
R1487 T1943 T1942 arg2Of paraffin,in
R1488 T1945 T1944 arg1Of and,","
R1489 T1946 T1945 arg2Of cut,and
R149 T284 T283 arg1Of blots,Western
R1490 T1946 T1947 arg1Of cut,into
R1491 T1948 T1947 arg2Of sections,into
R1492 T1948 T1949 arg1Of sections,(
R1493 T1948 T1952 arg1Of sections,as
R1494 T1950 T1949 arg2Of 7 μm,(
R1495 T1951 T1949 arg3Of ),(
R1496 T1953 T1952 arg2Of described,as
R1497 T1953 T1954 arg1Of described,previously
R1498 T1953 T1955 arg1Of described,[
R1499 T1956 T1955 arg2Of 8,[
R150 T285 T289 arg1Of ",",and
R1500 T1957 T1955 arg3Of ],[
R1501 T1959 T1958 arg1Of rats,Five
R1502 T1959 T1960 arg1Of rats,in
R1503 T1959 T1977 arg1Of rats,were
R1504 T1959 T1978 arg2Of rats,removed
R1505 T1959 T1980 arg2Of rats,stored
R1506 T1962 T1960 arg2Of group,in
R1507 T1962 T1961 arg1Of group,each
R1508 T1962 T1963 arg1Of group,at
R1509 T1965 T1963 arg2Of time,at
R151 T287 T285 arg2Of staining,","
R1510 T1965 T1964 arg1Of time,each
R1511 T1966 T1967 arg1Of point,were
R1512 T1966 T1968 arg2Of point,sacrificed
R1513 T1968 T1965 arg2Of sacrificed,time
R1514 T1968 T1967 arg2Of sacrificed,were
R1515 T1972 T1968 arg1Of injection,sacrificed
R1516 T1972 T1969 arg2Of injection,by
R1517 T1972 T1970 arg1Of injection,over
R1518 T1972 T1971 arg1Of injection,dose
R1519 T1972 T1973 arg1Of injection,of
R152 T287 T286 arg1Of staining,immunohistochemistry
R1520 T1976 T1973 arg2Of brains,of
R1521 T1976 T1974 arg1Of brains,Ketamine.
R1522 T1976 T1975 arg1Of brains,The
R1523 T1978 T1979 arg1Of removed,and
R1524 T1979 T1977 arg2Of and,were
R1525 T1980 T1979 arg2Of stored,and
R1526 T1980 T1981 arg1Of stored,at
R1527 T1983 T1981 arg2Of 80°C,at
R1528 T1983 T1982 arg1Of 80°C,minus
R1529 T1983 T1984 arg1Of 80°C,for
R153 T289 T275 arg1Of and,examined
R1530 T1985 T1986 arg1Of RT-PCR,and
R1531 T1986 T1984 arg2Of and,for
R1532 T1988 T1986 arg2Of Blots,and
R1533 T1988 T1987 arg1Of Blots,Western
R154 T289 T280 arg2Of and,by
R155 T289 T288 arg1Of and,","
R156 T290 T289 arg2Of EMSA,and
R157 T292 T291 arg2Of with,Compared
R158 T294 T292 arg2Of control,with
R159 T294 T293 arg1Of control,saline
R160 T298 T297 arg1Of mRNA,TLR4
R161 T298 T299 arg1Of mRNA,and
R162 T299 T296 arg1Of and,the
R163 T299 T302 arg1Of and,increased
R164 T299 T309 arg1Of and,peaked
R165 T299 T319 arg1Of and,decreased
R166 T299 T322 arg2Of and,maintained
R167 T300 T299 arg2Of protein,and
R168 T302 T308 arg1Of increased,","
R169 T303 T302 arg2Of starting,increased
R170 T303 T304 arg1Of starting,at
R171 T303 T306 arg1Of starting,after
R172 T305 T304 arg2Of 6 hours,at
R173 T307 T306 arg2Of ICH,after
R174 T308 T317 arg1Of ",",and
R175 T309 T308 arg2Of peaked,","
R176 T309 T310 arg1Of peaked,on
R1763 T2255 T2256 arg1Of Induction,of
R1764 T2258 T2256 arg2Of Hemorrhage,of
R1765 T2258 T2257 arg1Of Hemorrhage,Intracerebral
R1766 T2262 T2260 arg1Of hemorrhages,most
R1767 T2262 T2261 arg1Of hemorrhages,intracerebral
R1768 T2262 T2263 arg1Of hemorrhages,occur
R1769 T2263 T2259 arg2Of occur,Since
R177 T313 T310 arg2Of day,on
R1770 T2263 T2264 arg1Of occur,in
R1771 T2267 T2264 arg2Of ganglia,in
R1772 T2267 T2265 arg1Of ganglia,the
R1773 T2267 T2266 arg1Of ganglia,basal
R1774 T2267 T2268 arg1Of ganglia,clinically
R1775 T2273 T2270 arg2Of study,in
R1776 T2273 T2271 arg1Of study,the
R1777 T2273 T2272 arg1Of study,present
R1778 T2276 T2275 arg1Of model,rat
R1779 T2276 T2277 arg1Of model,of
R178 T313 T311 arg1Of day,the
R1780 T2276 T2279 arg1Of model,was
R1781 T2276 T2280 arg2Of model,induced
R1782 T2278 T2277 arg2Of ICH,of
R1783 T2280 T2259 arg1Of induced,Since
R1784 T2280 T2269 arg1Of induced,","
R1785 T2280 T2270 arg1Of induced,in
R1786 T2280 T2274 arg1Of induced,","
R1787 T2280 T2279 arg2Of induced,was
R1788 T2280 T2281 arg1Of induced,in
R1789 T2284 T2281 arg2Of ganglia,in
R179 T313 T312 arg1Of day,3rd
R1790 T2284 T2282 arg1Of ganglia,left
R1791 T2284 T2283 arg1Of ganglia,basal
R1792 T2285 T2286 arg1Of Rats,were
R1793 T2285 T2287 arg2Of Rats,anesthetized
R1794 T2287 T2286 arg2Of anesthetized,were
R1795 T2287 T2288 arg1Of anesthetized,with
R1796 T2291 T2288 arg2Of pentobarbital,with
R1797 T2291 T2289 arg1Of pentobarbital,intra-peritoneal
R1798 T2291 T2290 arg1Of pentobarbital,sodium
R1799 T2291 T2292 arg1Of pentobarbital,(
R180 T313 T314 arg1Of day,after
R1800 T2293 T2292 arg2Of 60 mg/kg,(
R1801 T2294 T2292 arg3Of ),(
R1802 T2298 T2297 arg2Of rectal,(
R1803 T2299 T2297 arg3Of ),(
R1804 T2300 T2295 arg1Of temperature,The
R1805 T2300 T2296 arg1Of temperature,body
R1806 T2300 T2297 arg1Of temperature,(
R1807 T2300 T2301 arg1Of temperature,was
R1808 T2300 T2302 arg2Of temperature,maintained
R1809 T2302 T2301 arg2Of maintained,was
R181 T315 T314 arg2Of ICH,after
R1810 T2302 T2303 arg1Of maintained,at
R1811 T2302 T2305 arg1Of maintained,during
R1812 T2304 T2303 arg2Of 37°C,at
R1813 T2307 T2305 arg2Of surgery,during
R1814 T2307 T2306 arg1Of surgery,the
R1815 T2307 T2308 arg1Of surgery,using
R1816 T2312 T2308 arg2Of system,using
R1817 T2312 T2309 arg1Of system,a
R1818 T2312 T2310 arg1Of system,feedback-controlled
R1819 T2312 T2311 arg1Of system,heating
R182 T317 T291 arg1Of and,Compared
R1820 T2314 T2313 arg1Of rats,The
R1821 T2314 T2315 arg1Of rats,were
R1822 T2314 T2316 arg2Of rats,positioned
R1823 T2316 T2315 arg2Of positioned,were
R1824 T2316 T2317 arg1Of positioned,in
R1825 T2316 T2322 arg1Of positioned,and
R1826 T2320 T2317 arg2Of frame,in
R1827 T2320 T2318 arg1Of frame,a
R1828 T2320 T2319 arg1Of frame,stereotactic
R1829 T2322 T2321 arg1Of and,","
R183 T317 T295 arg1Of and,","
R1830 T2324 T2323 arg1Of scalp,the
R1831 T2324 T2325 arg1Of scalp,was
R1832 T2324 T2326 arg2Of scalp,incised
R1833 T2326 T2322 arg2Of incised,and
R1834 T2326 T2325 arg2Of incised,was
R1835 T2326 T2327 arg1Of incised,along
R1836 T2329 T2327 arg2Of midline,along
R1837 T2329 T2328 arg1Of midline,the
R1838 T2333 T2330 arg2Of technique,Using
R1839 T2333 T2331 arg1Of technique,a
R184 T317 T301 arg1Of and,significantly
R1840 T2333 T2332 arg1Of technique,sterile
R1841 T2338 T2330 arg1Of hole,Using
R1842 T2338 T2335 arg1Of hole,a
R1843 T2338 T2336 arg1Of hole,1 mm
R1844 T2338 T2337 arg1Of hole,burr
R1845 T2338 T2339 arg1Of hole,was
R1846 T2338 T2340 arg2Of hole,opened
R1847 T2340 T2330 modOf opened,Using
R1848 T2340 T2334 arg1Of opened,","
R1849 T2340 T2339 arg2Of opened,was
R185 T317 T316 arg1Of and,","
R1850 T2340 T2341 arg1Of opened,in
R1851 T2343 T2341 arg2Of skull,in
R1852 T2343 T2342 arg1Of skull,the
R1853 T2343 T2344 arg1Of skull,on
R1854 T2349 T2344 arg2Of 3 mm,on
R1855 T2349 T2345 arg1Of 3 mm,the
R1856 T2349 T2346 arg1Of 3 mm,left
R1857 T2349 T2347 arg1Of 3 mm,coronal
R1858 T2349 T2348 arg1Of 3 mm,suture
R1859 T2349 T2350 arg1Of 3 mm,lateral
R186 T319 T320 arg1Of decreased,but
R1860 T2350 T2351 arg1Of lateral,to
R1861 T2353 T2351 arg2Of midline,to
R1862 T2353 T2352 arg1Of midline,the
R1863 T2357 T2354 arg1Of needle,A
R1864 T2357 T2355 arg1Of needle,blunt
R1865 T2357 T2356 arg1Of needle,26-gauge
R1866 T2357 T2358 arg1Of needle,was
R1867 T2357 T2359 arg2Of needle,inserted
R1868 T2359 T2358 arg2Of inserted,was
R1869 T2359 T2360 arg1Of inserted,into
R187 T320 T317 arg2Of but,and
R1870 T2359 T2365 arg1Of inserted,under
R1871 T2364 T2360 arg2Of ganglia,into
R1872 T2364 T2361 arg1Of ganglia,the
R1873 T2364 T2362 arg1Of ganglia,left
R1874 T2364 T2363 arg1Of ganglia,basal
R1875 T2367 T2365 arg2Of guidance,under
R1876 T2367 T2366 arg1Of guidance,stereotactic
R1877 T2367 T2368 arg1Of guidance,(
R1878 T2369 T2368 arg2Of coordinates,(
R1879 T2370 T2368 arg3Of :,(
R188 T320 T318 arg1Of but,then
R1880 T2371 T2372 arg1Of 0.2 mm,anterior
R1881 T2371 T2375 arg1Of 0.2 mm,ventral
R1882 T2371 T2377 arg1Of 0.2 mm,and
R1883 T2372 T2373 arg1Of anterior,","
R1884 T2375 T2373 arg2Of ventral,","
R1885 T2375 T2374 arg1Of ventral,6.0 mm
R1886 T2377 T2376 arg1Of and,","
R1887 T2378 T2377 arg2Of 3.0 mm,and
R1888 T2378 T2379 arg1Of 3.0 mm,lateral
R1889 T2379 T2380 arg1Of lateral,to
R189 T322 T320 arg2Of maintained,but
R1890 T2382 T2380 arg2Of midline,to
R1891 T2382 T2381 arg1Of midline,the
R1892 T2382 T2383 arg1Of midline,)
R1893 T2387 T2386 arg1Of 75 μL,a
R1894 T2387 T2388 arg1Of 75 μL,of
R1895 T2387 T2392 arg1Of 75 μL,was
R1896 T2387 T2393 arg2Of 75 μL,infused
R1897 T2391 T2388 arg2Of blood,of
R1898 T2391 T2389 arg1Of blood,autologous
R1899 T2391 T2390 arg1Of blood,whole
R190 T322 T321 arg1Of maintained,still
R1900 T2393 T2384 arg1Of infused,Then
R1901 T2393 T2385 arg1Of infused,","
R1902 T2393 T2392 arg2Of infused,was
R1903 T2393 T2394 arg1Of infused,at
R1904 T2396 T2394 arg2Of rate,at
R1905 T2396 T2395 arg1Of rate,a
R1906 T2396 T2397 arg1Of rate,of
R1907 T2396 T2399 arg1Of rate,with
R1908 T2398 T2397 arg2Of 20 μL/min,of
R1909 T2401 T2399 arg2Of use,with
R191 T322 T323 arg1Of maintained,at
R1910 T2401 T2400 arg1Of use,the
R1911 T2401 T2402 arg1Of use,of
R1912 T2405 T2402 arg2Of pump,of
R1913 T2405 T2403 arg1Of pump,a
R1914 T2405 T2404 arg1Of pump,microinfusion
R1915 T2408 T2406 arg2Of completion,After
R1916 T2408 T2407 arg1Of completion,the
R1917 T2408 T2409 arg1Of completion,of
R1918 T2411 T2409 arg2Of infusion,of
R1919 T2411 T2410 arg1Of infusion,the
R192 T322 T327 arg1Of maintained,on
R1920 T2414 T2413 arg1Of needle,the
R1921 T2414 T2415 arg1Of needle,was
R1922 T2414 T2416 arg2Of needle,withdrawn
R1923 T2416 T2415 arg2Of withdrawn,was
R1924 T2416 T2417 arg1Of withdrawn,quickly
R1925 T2420 T2419 arg1Of glue,cyanoacrylate
R1926 T2420 T2421 arg1Of glue,was
R1927 T2420 T2422 arg2Of glue,placed
R1928 T2422 T2421 arg2Of placed,was
R1929 T2422 T2423 arg1Of placed,around
R193 T322 T331 arg1Of maintained,after
R1930 T2422 T2428 arg1Of placed,and
R1931 T2426 T2423 arg2Of hole,around
R1932 T2426 T2424 arg1Of hole,the
R1933 T2426 T2425 arg1Of hole,burr
R1934 T2428 T2406 arg1Of and,After
R1935 T2428 T2412 arg1Of and,","
R1936 T2428 T2415 modOf and,was
R1937 T2428 T2418 arg1Of and,","
R1938 T2428 T2427 arg1Of and,","
R1939 T2431 T2429 arg1Of incision,the
R194 T326 T323 arg2Of level,at
R1940 T2431 T2430 arg1Of incision,skin
R1941 T2431 T2432 arg1Of incision,was
R1942 T2431 T2433 arg2Of incision,closed
R1943 T2433 T2428 arg2Of closed,and
R1944 T2433 T2432 arg2Of closed,was
R1945 T2433 T2434 arg1Of closed,with
R1946 T2435 T2434 arg2Of sutures,with
R1947 T2441 T2436 arg2Of rats,For
R1948 T2441 T2437 arg1Of rats,the
R1949 T2441 T2438 arg1Of rats,normal
R195 T326 T324 arg1Of level,a
R1950 T2441 T2439 arg1Of rats,saline
R1951 T2441 T2440 arg1Of rats,control
R1952 T2446 T2443 arg1Of saline,only
R1953 T2446 T2444 arg1Of saline,75 μL
R1954 T2446 T2445 arg1Of saline,normal
R1955 T2446 T2447 arg1Of saline,was
R1956 T2446 T2448 arg2Of saline,injected
R1957 T2448 T2436 arg1Of injected,For
R1958 T2448 T2442 arg1Of injected,","
R1959 T2448 T2447 arg2Of injected,was
R196 T326 T325 arg1Of level,higher
R197 T330 T327 arg2Of day,on
R198 T330 T328 arg1Of day,the
R199 T330 T329 arg1Of day,7th
R200 T332 T331 arg2Of ICH,after
R201 T332 T333 arg1Of ICH,(
R202 T334 T333 arg2Of P,(
R203 T334 T335 arg1Of P,<
R204 T335 T336 arg1Of <,.05
R205 T337 T333 arg3Of ),(
R206 T339 T338 arg1Of level,The
R207 T339 T340 arg1Of level,of
R208 T339 T342 arg1Of level,and
R209 T341 T340 arg2Of p-IκBα,of
R210 T342 T348 arg1Of and,increased
R211 T344 T342 arg2Of activity,and
R212 T344 T343 arg1Of activity,the
R213 T344 T345 arg1Of activity,of
R214 T346 T345 arg2Of NFκB,of
R215 T348 T347 arg1Of increased,also
R216 T348 T349 arg1Of increased,in
R217 T348 T352 arg1Of increased,after
R218 T351 T349 arg2Of brain,in
R2188 T2817 T2818 arg1Of Detection,of
R2189 T2817 T2821 arg1Of Detection,by
R219 T351 T350 arg1Of brain,the
R2190 T2820 T2818 arg2Of mRNA,of
R2191 T2820 T2819 arg1Of mRNA,TLR4
R2192 T2823 T2821 arg2Of Method,by
R2193 T2823 T2822 arg1Of Method,the
R2194 T2823 T2824 arg1Of Method,of
R2195 T2825 T2824 arg2Of RT-PCR,of
R2196 T2830 T2828 arg1Of samples,total
R2197 T2830 T2829 arg1Of samples,RNA
R2198 T2830 T2831 arg1Of samples,were
R2199 T2830 T2832 arg2Of samples,isolated
R220 T353 T352 arg2Of ICH,after
R2200 T2832 T2826 arg1Of isolated,Briefly
R2201 T2832 T2827 arg1Of isolated,","
R2202 T2832 T2831 arg2Of isolated,were
R2203 T2832 T2833 arg1Of isolated,from
R2204 T2835 T2833 arg2Of regions,from
R2205 T2835 T2834 arg1Of regions,peri-hemorrhage
R2206 T2835 T2836 arg1Of regions,in
R2207 T2839 T2836 arg2Of ganglia,in
R2208 T2839 T2837 arg1Of ganglia,left
R2209 T2839 T2838 arg1Of ganglia,basal
R221 T353 T354 arg1Of ICH,compared
R2210 T2839 T2840 arg1Of ganglia,using
R2211 T2840 T2847 arg1Of using,(
R2212 T2840 T2854 arg1Of using,according
R2213 T2843 T2841 arg1Of Total,Simply
R2214 T2843 T2842 arg1Of Total,P
R2215 T2846 T2840 arg2Of Kit,using
R2216 T2846 T2843 arg1Of Kit,Total
R2217 T2846 T2844 arg1Of Kit,RNA
R2218 T2846 T2845 arg1Of Kit,isolation
R2219 T2848 T2849 arg1Of BioFlux,","
R222 T355 T354 arg2Of with,compared
R2220 T2849 T2847 arg2Of ",",(
R2221 T2849 T2851 arg1Of ",",","
R2222 T2850 T2849 arg2Of HZ,","
R2223 T2852 T2851 arg2Of China,","
R2224 T2853 T2847 arg3Of ),(
R2225 T2855 T2854 arg2Of to,according
R2226 T2857 T2856 arg1Of manufacturer,the
R2227 T2857 T2858 arg2Of manufacturer,'s
R2228 T2859 T2855 arg2Of instructions,to
R2229 T2859 T2858 arg1Of instructions,'s
R223 T357 T355 arg2Of control,with
R2230 T2861 T2860 arg1Of quantity,The
R2231 T2861 T2862 arg1Of quantity,of
R2232 T2861 T2865 arg1Of quantity,was
R2233 T2861 T2866 arg2Of quantity,determined
R2234 T2861 T2875 arg1Of quantity,measuring
R2235 T2864 T2862 arg2Of RNA,of
R2236 T2864 T2863 arg1Of RNA,total
R2237 T2866 T2865 arg2Of determined,was
R2238 T2866 T2867 arg1Of determined,on
R2239 T2866 T2874 arg1Of determined,by
R224 T357 T356 arg1Of control,saline
R2240 T2869 T2867 arg2Of Nanodrop,on
R2241 T2869 T2868 arg1Of Nanodrop,a
R2242 T2869 T2870 arg1Of Nanodrop,(
R2243 T2872 T2870 arg2Of Spectrophotometer,(
R2244 T2872 T2871 arg1Of Spectrophotometer,ND-1000
R2245 T2873 T2870 arg3Of ),(
R2246 T2875 T2874 arg2Of measuring,by
R2247 T2875 T2878 arg1Of measuring,at
R2248 T2877 T2875 arg2Of density,measuring
R2249 T2877 T2876 arg1Of density,optical
R225 T360 T358 arg1Of study,The
R2250 T2879 T2880 arg1Of A260,and
R2251 T2881 T2880 arg2Of A280 nm,and
R2252 T2882 T2878 arg2Of wavelength,at
R2253 T2882 T2879 arg1Of wavelength,A260
R2254 T2882 T2881 arg1Of wavelength,A280 nm
R2255 T2886 T2885 arg1Of concentrations,the
R2256 T2886 T2887 arg1Of concentrations,of
R2257 T2886 T2889 arg1Of concentrations,were
R2258 T2886 T2890 arg2Of concentrations,adjusted
R2259 T2888 T2887 arg2Of mRNA,of
R226 T360 T359 arg1Of study,present
R2260 T2890 T2883 arg1Of adjusted,Then
R2261 T2890 T2884 arg1Of adjusted,","
R2262 T2890 T2889 arg2Of adjusted,were
R2263 T2890 T2891 arg1Of adjusted,to
R2264 T2892 T2891 arg2Of 1.0 g/mL,to
R2265 T2893 T2894 arg1Of RNA,was
R2266 T2893 T2895 arg2Of RNA,reverse-transcribed
R2267 T2893 T2902 arg1Of RNA,using
R2268 T2895 T2894 arg2Of reverse-transcribed,was
R2269 T2895 T2896 arg1Of reverse-transcribed,into
R227 T360 T362 arg1Of study,suggests
R2270 T2895 T2898 arg1Of reverse-transcribed,in
R2271 T2895 T2902 modOf reverse-transcribed,using
R2272 T2897 T2896 arg2Of cDNA,into
R2273 T2901 T2898 arg2Of system,in
R2274 T2901 T2899 arg1Of system,20 μL
R2275 T2901 T2900 arg1Of system,reaction
R2276 T2905 T2903 arg1Of Synthesis,Superscript
R2277 T2905 T2904 arg1Of Synthesis,First-Strand
R2278 T2906 T2902 arg2Of Kit,using
R2279 T2906 T2905 arg1Of Kit,Synthesis
R228 T362 T361 arg1Of suggests,firstly
R2280 T2906 T2907 arg1Of Kit,for
R2281 T2908 T2907 arg2Of RT-PCR,for
R2282 T2908 T2909 arg1Of RT-PCR,(
R2283 T2908 T2913 arg1Of RT-PCR,under
R2284 T2911 T2909 arg2Of Inc,(
R2285 T2911 T2910 arg1Of Inc,promega
R2286 T2912 T2909 arg3Of ),(
R2287 T2914 T2913 arg2Of conditions,under
R2288 T2914 T2915 arg2Of conditions,described
R2289 T2918 T2915 arg1Of supplier,described
R229 T366 T364 arg1Of signaling,TLR4-mediated
R2290 T2918 T2916 arg2Of supplier,by
R2291 T2918 T2917 arg1Of supplier,the
R2292 T2920 T2919 arg1Of microliter,One
R2293 T2920 T2921 arg1Of microliter,of
R2294 T2920 T2923 arg1Of microliter,was
R2295 T2920 T2924 arg2Of microliter,used
R2296 T2922 T2921 arg2Of cDNA,of
R2297 T2924 T2923 arg2Of used,was
R2298 T2926 T2924 arg3Of amplify,used
R2299 T2926 T2925 arg1Of amplify,to
R230 T366 T365 arg1Of signaling,NFκB
R2300 T2930 T2926 arg2Of fragment,amplify
R2301 T2930 T2927 arg1Of fragment,the
R2302 T2930 T2928 arg1Of fragment,TLR4
R2303 T2930 T2929 arg1Of fragment,gene
R2304 T2930 T2931 arg1Of fragment,with
R2305 T2934 T2932 arg1Of buffer,1×
R2306 T2934 T2933 arg1Of buffer,PCR
R2307 T2934 T2935 arg1Of buffer,","
R2308 T2935 T2937 arg1Of ",",","
R2309 T2936 T2935 arg2Of 1.5 mM MgCl2,","
R231 T366 T367 arg1Of signaling,participates
R2310 T2937 T2942 arg1Of ",",","
R2311 T2938 T2937 arg2Of 200 μM,","
R2312 T2938 T2939 arg1Of 200 μM,of
R2313 T2941 T2939 arg2Of dNTP,of
R2314 T2941 T2940 arg1Of dNTP,each
R2315 T2942 T2947 arg1Of ",",and
R2316 T2943 T2942 arg2Of 200 μM,","
R2317 T2943 T2944 arg1Of 200 μM,of
R2318 T2945 T2944 arg2Of primers,of
R2319 T2947 T2931 arg2Of and,with
R232 T367 T362 arg2Of participates,suggests
R2320 T2947 T2946 arg1Of and,","
R2321 T2951 T2947 arg2Of polymerase,and
R2322 T2951 T2948 arg1Of polymerase,2u
R2323 T2951 T2949 arg1Of polymerase,Taq
R2324 T2951 T2950 arg1Of polymerase,DNA
R2325 T2955 T2952 arg1Of gene,The
R2326 T2955 T2953 arg1Of gene,house
R2327 T2955 T2954 arg1Of gene,keep
R2328 T2955 T2956 arg1Of gene,(
R2329 T2955 T2959 arg1Of gene,was
R233 T367 T363 arg1Of participates,that
R2330 T2955 T2960 arg2Of gene,used
R2331 T2957 T2956 arg2Of β-actin,(
R2332 T2958 T2956 arg3Of ),(
R2333 T2960 T2959 arg2Of used,was
R2334 T2960 T2961 arg1Of used,as
R2335 T2964 T2961 arg2Of control,as
R2336 T2964 T2962 arg1Of control,an
R2337 T2964 T2963 arg1Of control,internal
R2338 T2968 T2965 arg1Of sequences,The
R2339 T2968 T2966 arg1Of sequences,PCR
R234 T367 T368 arg1Of participates,in
R2340 T2968 T2967 arg1Of sequences,primer
R2341 T2968 T2969 arg1Of sequences,were
R2342 T2968 T2970 arg2Of sequences,designed
R2343 T2970 T2969 arg2Of designed,were
R2344 T2970 T2971 arg1Of designed,according
R2345 T2972 T2971 arg2Of to,according
R2346 T2974 T2975 arg1Of TLR4,and
R2347 T2975 T2972 arg2Of and,to
R2348 T2975 T2973 arg1Of and,the
R2349 T2975 T2979 arg2Of and,reported
R235 T370 T368 arg2Of pathogenesis,in
R2350 T2978 T2975 arg2Of sequences,and
R2351 T2978 T2976 arg1Of sequences,β-actin
R2352 T2978 T2977 arg1Of sequences,gene
R2353 T2979 T2980 arg1Of reported,in
R2354 T2981 T2980 arg2Of GenBank,in
R2355 T2982 T2983 arg1Of TLR4,(
R2356 T2982 T2986 arg1Of TLR4,:
R2357 T2982 T2987 arg1Of TLR4,forward
R2358 T2982 T2988 arg1Of TLR4,:
R2359 T2984 T2983 arg2Of 145 bp,(
R236 T370 T369 arg1Of pathogenesis,the
R2360 T2985 T2983 arg3Of ),(
R2361 T2989 T2990 arg1Of 5′-AGCTTTGGTCAGTTGGCTCT-3′,;
R2362 T2990 T2992 arg1Of ;,:
R2363 T2991 T2990 arg2Of reverse,;
R2364 T2993 T2994 arg1Of 5′-CAGGATGACACCATTGAAGC-3′,;
R2365 T2994 T2996 arg1Of ;,(
R2366 T2994 T2999 arg1Of ;,:
R2367 T2994 T3000 arg1Of ;,forward
R2368 T2994 T3001 arg1Of ;,:
R2369 T2995 T2994 arg2Of β-actin,;
R237 T370 T371 arg1Of pathogenesis,of
R2370 T2997 T2996 arg2Of 701 bp,(
R2371 T2998 T2996 arg3Of ),(
R2372 T3002 T3003 arg1Of 5′-GCCAACCGTGAAAAAGATG-3′,;
R2373 T3003 T3005 arg1Of ;,:
R2374 T3004 T3003 arg2Of reverse,;
R2375 T3008 T3007 arg1Of cycles,Reaction
R2376 T3008 T3009 arg1Of cycles,were
R2377 T3008 T3010 arg2Of cycles,performed
R2378 T3010 T3009 arg2Of performed,were
R2379 T3010 T3011 arg1Of performed,at
R238 T370 T373 arg1Of pathogenesis,","
R2380 T3010 T3015 arg1Of performed,:
R2381 T3014 T3011 arg2Of condition,at
R2382 T3014 T3012 arg1Of condition,the
R2383 T3014 T3013 arg1Of condition,following
R2384 T3017 T3016 arg1Of 2 min,94°C
R2385 T3017 T3018 arg1Of 2 min,","
R2386 T3018 T3021 arg1Of ",",","
R2387 T3020 T3018 arg2Of 40 s,","
R2388 T3020 T3019 arg1Of 40 s,94°C
R2389 T3021 T3025 arg1Of ",",and
R239 T370 T374 arg1Of pathogenesis,which
R2390 T3023 T3021 arg2Of 40 s,","
R2391 T3023 T3022 arg1Of 40 s,55°C
R2392 T3025 T3024 arg1Of and,","
R2393 T3027 T3025 arg2Of 60 s,and
R2394 T3027 T3026 arg1Of 60 s,72°C
R2395 T3029 T3028 arg1Of reaction,The
R2396 T3029 T3030 arg1Of reaction,was
R2397 T3029 T3031 arg2Of reaction,stopped
R2398 T3031 T3030 arg2Of stopped,was
R2399 T3031 T3032 arg1Of stopped,after
R240 T370 T375 arg1Of pathogenesis,may
R2400 T3034 T3032 arg2Of cycles,after
R2401 T3034 T3033 arg1Of cycles,31
R2402 T3036 T3035 arg1Of products,PCR
R2403 T3036 T3037 arg1Of products,were
R2404 T3036 T3038 arg2Of products,electrophoresed
R2405 T3038 T3037 arg2Of electrophoresed,were
R2406 T3038 T3039 arg1Of electrophoresed,through
R2407 T3041 T3039 arg2Of gel,through
R2408 T3041 T3040 arg1Of gel,agarose
R2409 T3043 T3042 arg1Of Acquisition,Image
R241 T370 T376 arg1Of pathogenesis,become
R2410 T3043 T3044 arg1Of Acquisition,and
R2411 T3044 T3047 arg1Of and,were
R2412 T3044 T3048 arg2Of and,used
R2413 T3046 T3044 arg2Of software,and
R2414 T3046 T3045 arg1Of software,Analysis
R2415 T3048 T3047 arg2Of used,were
R2416 T3048 T3049 modOf used,to
R2417 T3050 T3049 arg1Of determine,to
R2418 T3052 T3050 arg2Of densities,determine
R2419 T3052 T3051 arg1Of densities,band
R242 T372 T371 arg2Of ICH,of
R2420 T3054 T3053 arg1Of abundance,The
R2421 T3054 T3055 arg1Of abundance,of
R2422 T3054 T3058 arg1Of abundance,was
R2423 T3054 T3059 arg2Of abundance,expressed
R2424 T3057 T3055 arg2Of mRNA,of
R2425 T3057 T3056 arg1Of mRNA,TLR4
R2426 T3059 T3058 arg2Of expressed,was
R2427 T3059 T3060 arg1Of expressed,as
R2428 T3062 T3060 arg2Of ratio,as
R2429 T3062 T3061 arg1Of ratio,the
R243 T376 T375 arg2Of become,may
R2430 T3062 T3063 arg1Of ratio,of
R2431 T3062 T3066 arg1Of ratio,to
R2432 T3065 T3063 arg2Of mRNA,of
R2433 T3065 T3064 arg1Of mRNA,TLR4
R2434 T3068 T3066 arg2Of mRNA,to
R2435 T3068 T3067 arg1Of mRNA,β-actin
R244 T379 T376 arg2Of target,become
R245 T379 T377 arg1Of target,a
R246 T379 T378 arg1Of target,therapeutic
R247 T379 T380 arg1Of target,for
R248 T383 T380 arg2Of damage,for
R249 T383 T381 arg1Of damage,ICH-induced
R25 T155 T156 arg1Of Activation,of
R250 T383 T382 arg1Of damage,brain
R26 T155 T160 arg1Of Activation,in
R27 T159 T156 arg2Of Signaling,of
R2754 T3542 T3543 arg1Of Immunohistochemistry,(
R2755 T3544 T3543 arg2Of IHC,(
R2756 T3545 T3543 arg3Of ),(
R2757 T3548 T3546 arg1Of staining,The
R2758 T3548 T3547 arg1Of staining,IHC
R2759 T3548 T3549 arg1Of staining,for
R2760 T3548 T3551 arg1Of staining,was
R2761 T3548 T3552 arg2Of staining,performed
R2762 T3550 T3549 arg2Of TLR4,for
R2763 T3552 T3551 arg2Of performed,was
R2764 T3552 T3553 arg1Of performed,as
R2765 T3552 T3556 arg1Of performed,[
R2766 T3554 T3553 arg2Of described,as
R2767 T3554 T3555 arg1Of described,previously
R2768 T3557 T3556 arg2Of 8,[
R2769 T3558 T3556 arg3Of ],[
R2770 T3561 T3559 arg1Of antibody,The
R2771 T3561 T3560 arg1Of antibody,primary
R2772 T3561 T3562 arg2Of antibody,employed
R2773 T3561 T3563 arg1Of antibody,was
R2774 T3563 T3566 arg1Of was,(
R2775 T3565 T3563 arg2Of anti-TLR4,was
R2776 T3565 T3564 arg1Of anti-TLR4,rabbit
R2777 T3567 T3566 arg2Of WuHan,(
R2778 T3567 T3568 arg1Of WuHan,","
R2779 T3567 T3569 arg1Of WuHan,BA1717
R2780 T3570 T3566 arg3Of ),(
R2781 T3574 T3571 arg1Of antibody,The
R2782 T3574 T3572 arg2Of antibody,biotinylated
R2783 T3574 T3573 arg1Of antibody,secondary
R2784 T3574 T3575 arg1Of antibody,and
R2785 T3575 T3584 arg1Of and,were
R2786 T3575 T3585 arg2Of and,obtained
R2787 T3577 T3575 arg2Of complexes,and
R2788 T3577 T3576 arg1Of complexes,antibody-biotin-avidin-peroxidase
R2789 T3577 T3578 arg1Of complexes,(
R2790 T3580 T3578 arg2Of reagent,(
R2791 T3580 T3579 arg1Of reagent,ABC
R2792 T3580 T3581 arg1Of reagent,","
R2793 T3582 T3581 arg2Of SC-2018,","
R2794 T3583 T3578 arg3Of ),(
R2795 T3585 T3584 arg2Of obtained,were
R2796 T3585 T3586 arg1Of obtained,from
R2797 T3590 T3586 arg2Of Inc.,from
R2798 T3590 T3587 arg1Of Inc.,Santa
R2799 T3590 T3588 arg1Of Inc.,Cruz
R28 T159 T157 arg1Of Signaling,TLR4-Mediated
R2800 T3590 T3589 arg1Of Inc.,Biotechnology
R2801 T3590 T3591 arg1Of Inc.,(
R2802 T3593 T3591 arg2Of Cruz,(
R2803 T3593 T3592 arg1Of Cruz,Santa
R2804 T3593 T3594 arg1Of Cruz,","
R2805 T3595 T3594 arg2Of CA,","
R2806 T3596 T3591 arg3Of ),(
R2807 T3597 T3598 arg2Of Slides,processed
R2808 T3598 T3599 arg1Of processed,without
R2809 T3601 T3599 arg2Of antibodies,without
R2810 T3601 T3600 arg1Of antibodies,primary
R2811 T3601 T3602 arg2Of antibodies,served
R2812 T3602 T3603 arg1Of served,as
R2813 T3605 T3603 arg2Of controls,as
R2814 T3605 T3604 arg1Of controls,negative
R2889 T3746 T3745 arg1Of Blots,Western
R2890 T3748 T3747 arg1Of proteins,Cellular
R2891 T3748 T3749 arg1Of proteins,were
R2892 T3748 T3750 arg2Of proteins,prepared
R2893 T3750 T3749 arg2Of prepared,were
R2894 T3750 T3751 arg1Of prepared,from
R2895 T3754 T3751 arg2Of hemispheres,from
R2896 T3754 T3752 arg1Of hemispheres,ICH
R2897 T3754 T3753 arg1Of hemispheres,cerebral
R2898 T3754 T3755 arg1Of hemispheres,","
R2899 T3754 T3756 arg2Of hemispheres,electrophoresed
R29 T159 T158 arg1Of Signaling,NFκB
R2900 T3754 T3761 arg2Of hemispheres,transferred
R2901 T3754 T3766 arg1Of hemispheres,(
R2902 T3756 T3757 arg1Of electrophoresed,with
R2903 T3756 T3760 arg1Of electrophoresed,and
R2904 T3759 T3757 arg2Of gel,with
R2905 T3759 T3758 arg1Of gel,SDS-polyacrylamide
R2906 T3761 T3760 arg2Of transferred,and
R2907 T3761 T3762 arg1Of transferred,onto
R2908 T3765 T3762 arg2Of membranes,onto
R2909 T3765 T3763 arg1Of membranes,Hybond
R2910 T3765 T3764 arg1Of membranes,ECL
R2911 T3768 T3766 arg2Of Pharmacia,(
R2912 T3768 T3767 arg1Of Pharmacia,Amersham
R2913 T3768 T3769 arg1Of Pharmacia,","
R2914 T3770 T3769 arg2Of Piscataway,","
R2915 T3770 T3771 arg1Of Piscataway,","
R2916 T3772 T3771 arg2Of NJ,","
R2917 T3773 T3766 arg3Of ),(
R2918 T3776 T3774 arg1Of membranes,The
R2919 T3776 T3775 arg1Of membranes,ECL
R2920 T3776 T3777 arg1Of membranes,were
R2921 T3776 T3778 arg2Of membranes,incubated
R2922 T3778 T3777 arg2Of incubated,were
R2923 T3778 T3779 arg1Of incubated,with
R2924 T3783 T3779 arg2Of antibody,with
R2925 T3783 T3780 arg1Of antibody,the
R2926 T3783 T3781 arg1Of antibody,appropriate
R2927 T3783 T3782 arg1Of antibody,primary
R2928 T3783 T3784 arg1Of antibody,(
R2929 T3783 T3789 arg2Of antibody,followed
R2930 T3785 T3784 arg2Of WuHan,(
R2931 T3785 T3786 arg1Of WuHan,","
R2932 T3787 T3786 arg2Of BA1717,","
R2933 T3788 T3784 arg3Of ),(
R2934 T3791 T3789 arg1Of incubation,followed
R2935 T3791 T3790 arg2Of incubation,by
R2936 T3791 T3792 arg1Of incubation,with
R2937 T3795 T3792 arg2Of antibodies,with
R2938 T3795 T3793 arg1Of antibodies,peroxidase-conjugated
R2939 T3795 T3794 arg1Of antibodies,secondary
R2940 T3795 T3796 arg1Of antibodies,(
R2941 T3798 T3796 arg2Of Bridge,(
R2942 T3798 T3797 arg1Of Bridge,Golden
R2943 T3798 T3799 arg1Of Bridge,","
R2944 T3800 T3799 arg2Of PV-6001,","
R2945 T3801 T3796 arg3Of ),(
R2946 T3803 T3802 arg1Of signals,The
R2947 T3803 T3804 arg1Of signals,were
R2948 T3803 T3805 arg2Of signals,detected
R2949 T3805 T3804 arg2Of detected,were
R2950 T3805 T3806 arg1Of detected,with
R2951 T3809 T3806 arg2Of system,with
R2952 T3809 T3807 arg1Of system,the
R2953 T3809 T3808 arg1Of system,ECL
R2954 T3809 T3810 arg1Of system,(
R2955 T3812 T3810 arg2Of Pharmacia,(
R2956 T3812 T3811 arg1Of Pharmacia,Amersham
R2957 T3813 T3810 arg3Of ),(
R2958 T3816 T3814 arg1Of membranes,The
R2959 T3816 T3815 arg1Of membranes,same
R2960 T3816 T3817 arg1Of membranes,were
R2961 T3816 T3818 arg2Of membranes,probed
R2962 T3816 T3832 arg1Of membranes,being
R2963 T3816 T3833 arg2Of membranes,washed
R2964 T3818 T3817 arg2Of probed,were
R2965 T3818 T3819 arg1Of probed,with
R2966 T3818 T3831 arg1Of probed,after
R2967 T3820 T3819 arg2Of anti-GAPDH,with
R2968 T3820 T3821 arg1Of anti-GAPDH,(
R2969 T3823 T3821 arg2Of dehydrogenase,(
R2970 T3823 T3822 arg1Of dehydrogenase,glyceraldehyde-3-phosphate
R2971 T3823 T3824 arg1Of dehydrogenase,","
R2972 T3823 T3828 arg1Of dehydrogenase,","
R2973 T3823 T3829 arg1Of dehydrogenase,Maine
R2974 T3825 T3826 arg1Of Biodesign,","
R2975 T3826 T3824 arg2Of ",",","
R2976 T3827 T3826 arg2Of Saco,","
R2977 T3830 T3821 arg3Of ),(
R2978 T3833 T3831 arg2Of washed,after
R2979 T3833 T3832 arg2Of washed,being
R2980 T3833 T3834 arg1Of washed,with
R2981 T3835 T3834 arg2Of stripping,with
R2982 T3836 T3835 arg2Of buffer,stripping
R2983 T3838 T3837 arg1Of signals,The
R2984 T3838 T3839 arg1Of signals,were
R2985 T3838 T3840 arg2Of signals,quantified
R2986 T3840 T3839 arg2Of quantified,were
R2987 T3840 T3841 arg1Of quantified,by
R2988 T3842 T3841 arg2Of scanning,by
R2989 T3843 T3844 arg1Of densitometry,and
R2990 T3844 T3842 arg2Of and,scanning
R2991 T3847 T3844 arg2Of analysis,and
R2992 T3847 T3845 arg1Of analysis,computer-assisted
R2993 T3847 T3846 arg1Of analysis,image
R30 T162 T160 arg2Of Brain,in
R31 T162 T161 arg1Of Brain,Hemorrhagic
R3109 T4038 T4035 arg1Of Assay,Electrophoretic
R3110 T4038 T4036 arg1Of Assay,Mobility
R3111 T4038 T4037 arg1Of Assay,Shift
R3112 T4038 T4039 arg1Of Assay,(
R3113 T4040 T4039 arg2Of EMSA,(
R3114 T4041 T4039 arg3Of ),(
R3115 T4043 T4042 arg1Of proteins,Nuclear
R3116 T4043 T4044 arg1Of proteins,were
R3117 T4043 T4045 arg2Of proteins,isolated
R3118 T4045 T4044 arg2Of isolated,were
R3119 T4045 T4046 arg1Of isolated,from
R3120 T4048 T4046 arg2Of tissue,from
R3121 T4048 T4047 arg1Of tissue,brain
R3122 T4052 T4051 arg2Of removal,after
R3123 T4052 T4053 arg1Of removal,of
R3124 T4054 T4053 arg2Of supernatant,of
R3125 T4054 T4055 arg1Of supernatant,(
R3126 T4057 T4055 arg2Of extract,(
R3127 T4057 T4056 arg1Of extract,cytoplasmic
R3128 T4058 T4055 arg3Of ),(
R3129 T4061 T4060 arg1Of pellets,the
R3130 T4061 T4062 arg1Of pellets,were
R3131 T4061 T4063 arg2Of pellets,resuspended
R3132 T4063 T4049 arg1Of resuspended,Briefly
R3133 T4063 T4050 arg1Of resuspended,","
R3134 T4063 T4051 arg1Of resuspended,after
R3135 T4063 T4059 arg1Of resuspended,","
R3136 T4063 T4062 arg2Of resuspended,were
R3137 T4063 T4064 arg1Of resuspended,in
R3138 T4067 T4064 arg2Of reagent,in
R3139 T4067 T4065 arg1Of reagent,nuclear
R3140 T4067 T4066 arg1Of reagent,extraction
R3141 T4069 T4068 arg1Of tubes,The
R3142 T4069 T4070 arg1Of tubes,containing
R3143 T4069 T4072 arg1Of tubes,were
R3144 T4069 T4073 arg2Of tubes,put
R3145 T4071 T4070 arg2Of pellets,containing
R3146 T4073 T4072 arg2Of put,were
R3147 T4073 T4074 arg1Of put,on
R3148 T4073 T4076 arg1Of put,for
R3149 T4073 T4081 arg1Of put,minutes
R3150 T4073 T4082 arg1Of put,","
R3151 T4073 T4083 arg1Of put,for
R3152 T4075 T4074 arg2Of vortex,on
R3153 T4078 T4076 arg2Of seconds,for
R3154 T4078 T4077 arg1Of seconds,15
R3155 T4081 T4079 arg1Of minutes,every
R3156 T4081 T4080 arg1Of minutes,10
R3157 T4085 T4083 arg2Of total,for
R3158 T4085 T4084 arg1Of total,a
R3159 T4085 T4086 arg1Of total,of
R3160 T4088 T4086 arg2Of minutes,of
R3161 T4088 T4087 arg1Of minutes,40
R3162 T4090 T4089 arg1Of tubes,The
R3163 T4090 T4091 arg1Of tubes,were
R3164 T4090 T4092 arg2Of tubes,centrifuged
R3165 T4092 T4091 arg2Of centrifuged,were
R3166 T4092 T4093 arg1Of centrifuged,at
R3167 T4095 T4093 arg2Of speed,at
R3168 T4095 T4094 arg1Of speed,maximum
R3169 T4095 T4096 arg1Of speed,(
R3170 T4095 T4100 arg1Of speed,in
R3171 T4098 T4096 arg2Of × g,(
R3172 T4098 T4097 arg1Of × g,"~16,000"
R3173 T4099 T4096 arg3Of ),(
R3174 T4103 T4100 arg2Of centrifuge,in
R3175 T4103 T4101 arg1Of centrifuge,a
R3176 T4103 T4102 arg1Of centrifuge,micro
R3177 T4103 T4104 arg1Of centrifuge,for
R3178 T4106 T4104 arg2Of minutes,for
R3179 T4106 T4105 arg1Of minutes,10
R3180 T4108 T4107 arg1Of supernatants,The
R3181 T4108 T4109 arg1Of supernatants,(
R3182 T4108 T4113 arg1Of supernatants,were
R3183 T4108 T4114 arg2Of supernatants,transferred
R3184 T4108 T4121 arg2Of supernatants,stored
R3185 T4111 T4109 arg2Of extract,(
R3186 T4111 T4110 arg1Of extract,nuclear
R3187 T4112 T4109 arg3Of ),(
R3188 T4114 T4115 arg1Of transferred,to
R3189 T4114 T4120 arg1Of transferred,and
R3190 T4119 T4115 arg2Of tube,to
R3191 T4119 T4116 arg1Of tube,a
R3192 T4119 T4117 arg1Of tube,clean
R3193 T4119 T4118 arg1Of tube,prechilled
R3194 T4120 T4113 arg2Of and,were
R3195 T4121 T4120 arg2Of stored,and
R3196 T4121 T4122 arg1Of stored,at
R3197 T4121 T4124 arg1Of stored,until
R3198 T4123 T4122 arg2Of −80°C,at
R3199 T4125 T4124 arg2Of use,until
R32 T162 T163 arg1Of Brain,in
R3200 T4126 T4127 arg1Of EMSA,was
R3201 T4126 T4128 arg2Of EMSA,performed
R3202 T4128 T4127 arg2Of performed,was
R3203 T4128 T4129 arg1Of performed,as
R3204 T4128 T4132 arg1Of performed,[
R3205 T4130 T4129 arg2Of described,as
R3206 T4130 T4131 arg1Of described,previously
R3207 T4133 T4132 arg2Of 8,[
R3208 T4134 T4132 arg3Of ],[
R3209 T4137 T4135 arg1Of activity,NFκB
R3210 T4137 T4136 arg1Of activity,binding
R3211 T4137 T4138 arg1Of activity,was
R3212 T4137 T4139 arg2Of activity,examined
R3213 T4139 T4138 arg2Of examined,was
R3214 T4139 T4140 arg1Of examined,in
R3215 T4145 T4140 arg2Of mixture,in
R3216 T4145 T4141 arg1Of mixture,a
R3217 T4145 T4142 arg1Of mixture,15 μL
R3218 T4145 T4143 arg1Of mixture,binding
R3219 T4145 T4144 arg1Of mixture,reaction
R3220 T4145 T4146 arg1Of mixture,containing
R3221 T4147 T4148 arg1Of 15 μg,of
R3222 T4147 T4151 arg1Of 15 μg,and
R3223 T4150 T4148 arg2Of proteins,of
R3224 T4150 T4149 arg1Of proteins,nuclear
R3225 T4151 T4146 arg2Of and,containing
R3226 T4152 T4153 arg1Of 35 fmol,[
R3227 T4154 T4153 arg2Of γ-32P,[
R3228 T4155 T4153 arg3Of ],[
R3229 T4160 T4151 arg2Of oligonucleotide,and
R3230 T4160 T4152 arg1Of oligonucleotide,35 fmol
R3231 T4160 T4156 arg2Of oligonucleotide,labeled
R3232 T4160 T4157 arg1Of oligonucleotide,double-stranded
R3233 T4160 T4158 arg1Of oligonucleotide,NFκB
R3234 T4160 T4159 arg1Of oligonucleotide,consensus
R3235 T4164 T4161 arg1Of assay,A
R3236 T4164 T4162 arg1Of assay,super
R3237 T4164 T4163 arg1Of assay,shift
R3238 T4164 T4165 arg1Of assay,using
R3239 T4164 T4171 arg1Of assay,was
R3240 T4164 T4172 arg2Of assay,performed
R3241 T4166 T4165 arg2Of antibodies,using
R3242 T4166 T4167 arg1Of antibodies,to
R3243 T4168 T4169 arg1Of P65,and
R3244 T4169 T4167 arg2Of and,to
R3245 T4170 T4169 arg2Of P50,and
R3246 T4172 T4171 arg2Of performed,was
R3247 T4172 T4173 modOf performed,to
R3248 T4174 T4173 arg1Of confirm,to
R3249 T4177 T4174 arg2Of specificity,confirm
R3250 T4177 T4175 arg1Of specificity,NFκB
R3251 T4177 T4176 arg1Of specificity,binding
R3252 T4177 T4178 arg1Of specificity,as
R3253 T4180 T4178 arg2Of described,as
R3254 T4180 T4179 arg1Of described,previously
R33 T164 T163 arg2Of Rats,in
R34 T165 T166 arg1Of Inflammation,and
R3420 T4387 T4386 arg1Of Analysis,Statistical
R3421 T4389 T4388 arg1Of data,All
R3422 T4389 T4390 arg1Of data,were
R3423 T4389 T4391 arg2Of data,presented
R3424 T4391 T4390 arg2Of presented,were
R3425 T4391 T4392 arg1Of presented,as
R3426 T4395 T4392 arg2Of SEM,as
R3427 T4395 T4393 arg1Of SEM,mean
R3428 T4395 T4394 arg1Of SEM,±
R3429 T4397 T4396 arg1Of measurements,The
R3430 T4397 T4398 arg1Of measurements,were
R3431 T4397 T4399 arg2Of measurements,analyzed
R3432 T4399 T4398 arg2Of analyzed,were
R3433 T4402 T4399 arg1Of analysis,analyzed
R3434 T4402 T4400 arg2Of analysis,by
R3435 T4402 T4401 arg1Of analysis,one-way
R3436 T4402 T4403 arg1Of analysis,of
R3437 T4404 T4405 arg1Of variance,(
R3438 T4404 T4408 arg1Of variance,or
R3439 T4406 T4405 arg2Of ANOVA,(
R3440 T4407 T4405 arg3Of ),(
R3441 T4408 T4403 arg2Of or,of
R3442 T4409 T4410 arg2Of Student,'s
R3443 T4411 T4408 arg2Of t-test,or
R3444 T4411 T4410 arg1Of t-test,'s
R3445 T4414 T4415 arg1Of <,.05
R3446 T4416 T4412 arg1Of level,The
R3447 T4416 T4413 arg1Of level,P
R3448 T4416 T4414 arg1Of level,<
R3449 T4416 T4417 arg1Of level,of
R3450 T4416 T4419 arg1Of level,was
R3451 T4416 T4420 arg2Of level,used
R3452 T4418 T4417 arg2Of probability,of
R3453 T4420 T4419 arg2Of used,was
R3454 T4420 T4421 arg1Of used,as
R3455 T4423 T4421 arg2Of criteria,as
R3456 T4423 T4422 arg1Of criteria,the
R3457 T4423 T4424 arg1Of criteria,of
R3458 T4425 T4424 arg2Of significance,of
R35 T166 T168 arg1Of and,play
R3514 T4545 T4544 arg1Of mRNA,TLR4
R3515 T4545 T4546 arg2Of mRNA,Increased
R3516 T4546 T4547 arg1Of Increased,in
R3517 T4549 T4547 arg2Of Tissue,in
R3518 T4549 T4548 arg1Of Tissue,Brain
R3519 T4549 T4550 arg1Of Tissue,after
R3520 T4551 T4550 arg2Of ICH,after
R3521 T4554 T4552 arg1Of levels,TLR4
R3522 T4554 T4553 arg1Of levels,mRNA
R3523 T4554 T4555 arg1Of levels,were
R3524 T4554 T4556 arg2Of levels,detected
R3525 T4556 T4555 arg2Of detected,were
R3526 T4558 T4556 arg1Of Rt-PCR,detected
R3527 T4558 T4557 arg2Of Rt-PCR,by
R3528 T4561 T4559 arg1Of level,The
R3529 T4561 T4560 arg1Of level,low
R3530 T4561 T4562 arg1Of level,of
R3531 T4561 T4565 arg1Of level,was
R3532 T4561 T4566 arg2Of level,observed
R3533 T4564 T4562 arg2Of mRNA,of
R3534 T4564 T4563 arg1Of mRNA,TLR4
R3535 T4566 T4565 arg2Of observed,was
R3536 T4566 T4567 arg1Of observed,in
R3537 T4571 T4567 arg2Of tissue,in
R3538 T4571 T4568 arg1Of tissue,normal
R3539 T4571 T4569 arg1Of tissue,rat
R3540 T4571 T4570 arg1Of tissue,brain
R3541 T4576 T4572 arg2Of group,In
R3542 T4576 T4573 arg1Of group,the
R3543 T4576 T4574 arg1Of group,saline
R3544 T4576 T4575 arg1Of group,control
R3545 T4580 T4578 arg1Of mRNA,the
R3546 T4580 T4579 arg1Of mRNA,TLR4
R3547 T4580 T4582 arg1Of mRNA,increased
R3548 T4580 T4585 arg1Of mRNA,was
R3549 T4580 T4588 arg1Of mRNA,different
R3550 T4582 T4584 arg1Of increased,but
R3551 T4584 T4572 arg1Of but,In
R3552 T4584 T4577 arg1Of but,","
R3553 T4584 T4581 arg1Of but,slightly
R3554 T4584 T4583 arg1Of but,","
R3555 T4585 T4584 arg2Of was,but
R3556 T4585 T4586 arg1Of was,not
R3557 T4588 T4585 arg2Of different,was
R3558 T4588 T4587 arg1Of different,significantly
R3559 T4588 T4589 arg1Of different,from
R3560 T4591 T4589 arg2Of group,from
R3561 T4591 T4590 arg1Of group,normal
R3562 T4596 T4594 arg1Of mRNA,the
R3563 T4596 T4595 arg1Of mRNA,TLR4
R3564 T4596 T4597 arg1Of mRNA,after
R3565 T4596 T4600 arg1Of mRNA,increased
R3566 T4596 T4612 arg1Of mRNA,peaked
R3567 T4596 T4622 arg1Of mRNA,decreased
R3568 T4596 T4637 arg1Of mRNA,maintained
R3569 T4598 T4597 arg2Of ICH,after
R3570 T4600 T4611 arg1Of increased,","
R3571 T4601 T4600 arg2Of starting,increased
R3572 T4601 T4602 arg1Of starting,from
R3573 T4601 T4604 arg1Of starting,after
R3574 T4603 T4602 arg2Of 6 hours,from
R3575 T4605 T4604 arg2Of ICH,after
R3576 T4605 T4606 arg1Of ICH,(
R3577 T4607 T4606 arg2Of P,(
R3578 T4607 T4608 arg1Of P,<
R3579 T4608 T4609 arg1Of <,.05
R3580 T4610 T4606 arg3Of ),(
R3581 T4611 T4620 arg1Of ",",and
R3582 T4612 T4611 arg2Of peaked,","
R3583 T4612 T4613 arg1Of peaked,on
R3584 T4616 T4613 arg2Of day,on
R3585 T4616 T4614 arg1Of day,the
R3586 T4616 T4615 arg1Of day,3rd
R3587 T4616 T4617 arg1Of day,after
R3588 T4618 T4617 arg2Of ICH,after
R3589 T4620 T4592 arg1Of and,However
R3590 T4620 T4593 arg1Of and,","
R3591 T4620 T4599 arg1Of and,significantly
R3592 T4620 T4619 arg1Of and,","
R3593 T4622 T4623 arg1Of decreased,on
R3594 T4622 T4627 arg1Of decreased,after
R3595 T4622 T4635 arg1Of decreased,but
R3596 T4626 T4623 arg2Of day,on
R3597 T4626 T4624 arg1Of day,the
R3598 T4626 T4625 arg1Of day,7th
R3599 T4628 T4627 arg2Of ICH,after
R36 T167 T166 arg2Of immunity,and
R3600 T4628 T4629 arg1Of ICH,(
R3601 T4630 T4629 arg2Of P,(
R3602 T4630 T4631 arg1Of P,<
R3603 T4631 T4632 arg1Of <,.05
R3604 T4633 T4629 arg3Of ),(
R3605 T4635 T4620 arg2Of but,and
R3606 T4635 T4621 arg1Of but,then
R3607 T4635 T4634 arg1Of but,","
R3608 T4637 T4635 arg2Of maintained,but
R3609 T4637 T4636 arg1Of maintained,still
R3610 T4637 T4641 arg1Of maintained,compared
R3611 T4640 T4637 arg2Of level,maintained
R3612 T4640 T4638 arg1Of level,a
R3613 T4640 T4639 arg1Of level,higher
R3614 T4642 T4641 arg2Of with,compared
R3615 T4644 T4642 arg2Of control,with
R3616 T4644 T4643 arg1Of control,saline
R3617 T4644 T4645 arg1Of control,(
R3618 T4646 T4645 arg2Of P,(
R3619 T4646 T4647 arg1Of P,<
R3620 T4646 T4649 arg1Of P,","
R3621 T4647 T4648 arg1Of <,.05
R3622 T4650 T4649 arg2Of Figure,","
R3623 T4650 T4651 arg1Of Figure,1
R3624 T4652 T4645 arg3Of ),(
R37 T168 T172 arg1Of play,in
R38 T171 T168 arg2Of role,play
R3804 T4959 T4960 arg1Of Expression,of
R3805 T4959 T4963 arg2Of Expression,Increased
R3806 T4962 T4960 arg2Of Protein,of
R3807 T4962 T4961 arg1Of Protein,TLR4
R3808 T4963 T4964 arg1Of Increased,in
R3809 T4966 T4964 arg2Of Tissue,in
R3810 T4966 T4965 arg1Of Tissue,Brain
R3811 T4966 T4967 arg1Of Tissue,after
R3812 T4968 T4967 arg2Of ICH,after
R3813 T4970 T4969 arg1Of investigate,To
R3814 T4973 T4970 arg2Of TLR4,investigate
R3815 T4973 T4971 arg1Of TLR4,the
R3816 T4973 T4972 arg2Of TLR4,increased
R3817 T4973 T4974 arg1Of TLR4,at
R3818 T4977 T4974 arg2Of level,at
R3819 T4977 T4975 arg1Of level,the
R3820 T4977 T4976 arg1Of level,protein
R3821 T4980 T4970 arg1Of expression,investigate
R3822 T4980 T4979 arg1Of expression,the
R3823 T4980 T4981 arg1Of expression,of
R3824 T4980 T4984 arg1Of expression,was
R3825 T4980 T4985 arg2Of expression,measured
R3826 T4983 T4981 arg2Of protein,of
R3827 T4983 T4982 arg1Of protein,TLR4
R3828 T4985 T4969 modOf measured,To
R3829 T4985 T4978 arg1Of measured,","
R3830 T4985 T4984 arg2Of measured,was
R3831 T4985 T4986 arg1Of measured,in
R3832 T4988 T4986 arg2Of tissue,in
R3833 T4988 T4987 arg1Of tissue,brain
R3834 T4991 T4985 arg1Of method,measured
R3835 T4991 T4989 arg2Of method,by
R3836 T4991 T4990 arg1Of method,the
R3837 T4991 T4992 arg1Of method,of
R3838 T4994 T4992 arg2Of Blots,of
R3839 T4994 T4993 arg1Of Blots,Western
R3840 T4994 T4995 arg1Of Blots,using
R3841 T4997 T4995 arg2Of antibodies,using
R3842 T4997 T4996 arg1Of antibodies,specific
R3843 T4997 T4998 arg1Of antibodies,for
R3844 T4999 T4998 arg2Of TLR4,for
R3845 T5001 T5000 arg1Of results,Our
R3846 T5001 T5002 arg1Of results,showed
R3847 T5006 T5004 arg1Of level,a
R3848 T5006 T5005 arg1Of level,low
R3849 T5006 T5007 arg1Of level,of
R3850 T5006 T5010 arg1Of level,was
R3851 T5006 T5011 arg1Of level,detectable
R3852 T5009 T5007 arg2Of protein,of
R3853 T5009 T5008 arg1Of protein,TLR4
R3854 T5010 T5002 arg2Of was,showed
R3855 T5010 T5003 arg1Of was,that
R3856 T5011 T5010 arg2Of detectable,was
R3857 T5011 T5012 arg1Of detectable,in
R3858 T5016 T5012 arg2Of group,in
R3859 T5016 T5013 arg1Of group,the
R3860 T5016 T5014 arg1Of group,saline
R3861 T5016 T5015 arg1Of group,control
R3862 T5018 T5017 arg1Of expression,The
R3863 T5018 T5019 arg1Of expression,of
R3864 T5018 T5022 arg1Of expression,increased
R3865 T5018 T5034 arg1Of expression,peaked
R3866 T5018 T5044 arg1Of expression,decreased
R3867 T5018 T5047 arg2Of expression,maintained
R3868 T5020 T5019 arg2Of TLR4,of
R3869 T5022 T5033 arg1Of increased,","
R3870 T5023 T5022 arg2Of starting,increased
R3871 T5023 T5024 arg1Of starting,from
R3872 T5023 T5026 arg1Of starting,after
R3873 T5025 T5024 arg2Of 6 hours,from
R3874 T5027 T5026 arg2Of ICH,after
R3875 T5027 T5028 arg1Of ICH,(
R3876 T5029 T5028 arg2Of P,(
R3877 T5029 T5030 arg1Of P,<
R3878 T5030 T5031 arg1Of <,.05
R3879 T5032 T5028 arg3Of ),(
R3880 T5033 T5042 arg1Of ",",and
R3881 T5034 T5033 arg2Of peaked,","
R3882 T5034 T5035 arg1Of peaked,on
R3883 T5038 T5035 arg2Of day,on
R3884 T5038 T5036 arg1Of day,the
R3885 T5038 T5037 arg1Of day,3rd
R3886 T5038 T5039 arg1Of day,after
R3887 T5040 T5039 arg2Of ICH,after
R3888 T5042 T5021 arg1Of and,significantly
R3889 T5042 T5041 arg1Of and,","
R3890 T5044 T5045 arg1Of decreased,but
R3891 T5045 T5042 arg2Of but,and
R3892 T5045 T5043 arg1Of but,then
R3893 T5047 T5045 arg2Of maintained,but
R3894 T5047 T5046 arg1Of maintained,still
R3895 T5047 T5048 arg1Of maintained,at
R3896 T5047 T5052 arg1Of maintained,on
R3897 T5047 T5056 arg1Of maintained,after
R3898 T5051 T5048 arg2Of level,at
R3899 T5051 T5049 arg1Of level,a
R39 T171 T169 arg1Of role,a
R3900 T5051 T5050 arg1Of level,high
R3901 T5055 T5052 arg2Of day,on
R3902 T5055 T5053 arg1Of day,the
R3903 T5055 T5054 arg1Of day,7th
R3904 T5057 T5056 arg2Of ICH,after
R3905 T5057 T5058 arg1Of ICH,(
R3906 T5059 T5058 arg2Of P,(
R3907 T5059 T5060 arg1Of P,<
R3908 T5059 T5062 arg1Of P,","
R3909 T5060 T5061 arg1Of <,.05
R3910 T5063 T5062 arg2Of Figure,","
R3911 T5063 T5064 arg1Of Figure,2
R3912 T5065 T5058 arg3Of ),(
R3913 T5067 T5066 arg1Of observation,This
R3914 T5067 T5068 arg1Of observation,of
R3915 T5067 T5071 arg1Of observation,was
R3916 T5067 T5072 arg1Of observation,consistent
R3917 T5070 T5068 arg2Of protein,of
R3918 T5070 T5069 arg1Of protein,TLR4
R3919 T5072 T5071 arg2Of consistent,was
R3920 T5072 T5073 arg1Of consistent,with
R3921 T5076 T5073 arg2Of profile,with
R3922 T5076 T5074 arg1Of profile,the
R3923 T5076 T5075 arg1Of profile,temporal
R3924 T5076 T5077 arg1Of profile,of
R3925 T5076 T5081 arg1Of profile,after
R3926 T5080 T5077 arg2Of mRNA,of
R3927 T5080 T5078 arg1Of mRNA,the
R3928 T5080 T5079 arg1Of mRNA,TLR4
R3929 T5082 T5081 arg2Of ICH,after
R40 T171 T170 arg1Of role,crucial
R41 T174 T172 arg2Of pathogenesis,in
R4108 T5392 T5393 arg1Of Distribution,of
R4109 T5392 T5395 arg1Of Distribution,in
R4110 T5392 T5399 arg2Of Distribution,ICH
R4111 T5394 T5393 arg2Of TLR4,of
R4112 T5397 T5395 arg2Of Subjected,in
R4113 T5397 T5396 arg1Of Subjected,Brain
R4114 T5399 T5398 arg1Of ICH,to
R4115 T5401 T5400 arg1Of explore,To
R4116 T5403 T5401 arg2Of distribution,explore
R4117 T5403 T5402 arg1Of distribution,the
R4118 T5403 T5404 arg1Of distribution,of
R4119 T5406 T5404 arg2Of protein,of
R4120 T5406 T5405 arg1Of protein,TLR4
R4121 T5409 T5401 arg1Of TLR4,explore
R4122 T5409 T5408 arg1Of TLR4,the
R4123 T5409 T5410 arg1Of TLR4,was
R4124 T5409 T5411 arg2Of TLR4,detected
R4125 T5411 T5400 modOf detected,To
R4126 T5411 T5407 arg1Of detected,","
R4127 T5411 T5410 arg2Of detected,was
R4128 T5413 T5411 arg1Of immunohistochemistry,detected
R4129 T5413 T5412 arg2Of immunohistochemistry,by
R4130 T5413 T5414 arg1Of immunohistochemistry,(
R4131 T5415 T5414 arg2Of IHC,(
R4132 T5416 T5414 arg3Of ),(
R4133 T5417 T5418 arg1Of Results,showed
R4134 T5421 T5420 arg1Of immunoreactivity,TLR4
R4135 T5421 T5422 arg1Of immunoreactivity,was
R4136 T5421 T5424 arg1Of immunoreactivity,detectable
R4137 T5422 T5418 arg2Of was,showed
R4138 T5422 T5419 arg1Of was,that
R4139 T5422 T5423 arg1Of was,not
R4140 T5424 T5422 arg2Of detectable,was
R4141 T5424 T5425 arg1Of detectable,in
R4142 T5427 T5425 arg2Of tissue,in
R4143 T5427 T5426 arg1Of tissue,brain
R4144 T5427 T5428 arg1Of tissue,from
R4145 T5429 T5430 arg1Of normal,and
R4146 T5431 T5430 arg2Of sham,and
R4147 T5432 T5428 arg2Of control,from
R4148 T5432 T5429 arg1Of control,normal
R4149 T5432 T5431 arg1Of control,sham
R4150 T5435 T5436 arg1Of immunoreactivity,for
R4151 T5435 T5438 arg1Of immunoreactivity,was
R4152 T5435 T5440 arg2Of immunoreactivity,demonstrated
R4153 T5437 T5436 arg2Of TLR4,for
R4154 T5440 T5433 arg1Of demonstrated,However
R4155 T5440 T5434 arg1Of demonstrated,","
R4156 T5440 T5438 arg2Of demonstrated,was
R4157 T5440 T5439 arg1Of demonstrated,consistently
R4158 T5440 T5441 arg1Of demonstrated,in
R4159 T5443 T5442 arg1Of areas,peri-hemorrhage
R4160 T5443 T5444 arg1Of areas,","
R4161 T5443 T5453 arg1Of areas,and
R4162 T5446 T5445 arg1Of hippocampus,the
R4163 T5446 T5447 arg1Of hippocampus,","
R4164 T5446 T5449 arg1Of hippocampus,","
R4165 T5448 T5447 arg2Of cortex,","
R4166 T5449 T5444 arg2Of ",",","
R4167 T5451 T5449 arg2Of nuclei,","
R4168 T5451 T5450 arg1Of nuclei,thalamic
R4169 T5453 T5441 arg2Of and,in
R4170 T5453 T5452 arg1Of and,","
R4171 T5457 T5453 arg2Of tracts,and
R4172 T5457 T5454 arg1Of tracts,some
R4173 T5457 T5455 arg1Of tracts,white
R4174 T5457 T5456 arg1Of tracts,matter
R4175 T5457 T5458 arg1Of tracts,(
R4176 T5459 T5458 arg2Of Figure,(
R4177 T5459 T5460 arg1Of Figure,3
R4178 T5461 T5458 arg3Of ),(
R42 T174 T173 arg1Of pathogenesis,the
R4281 T5666 T5667 arg1Of Activation,of
R4282 T5670 T5667 arg2Of Signaling,of
R4283 T5670 T5668 arg1Of Signaling,TLR4-Mediated
R4284 T5670 T5669 arg1Of Signaling,NF-Kappa-B
R4285 T5671 T5672 arg1Of Activation,of
R4286 T5671 T5674 arg1Of Activation,induces
R4287 T5673 T5672 arg2Of TLR4,of
R4288 T5676 T5674 arg2Of phosphorylation,induces
R4289 T5676 T5675 arg1Of phosphorylation,the
R4290 T5676 T5677 arg1Of phosphorylation,of
R4291 T5678 T5677 arg2Of inhibitor,of
R4292 T5678 T5679 arg1Of inhibitor,of
R4293 T5680 T5679 arg2Of kappa-B,of
R4294 T5680 T5681 arg1Of kappa-B,(
R4295 T5680 T5684 arg1Of kappa-B,","
R4296 T5680 T5685 arg1Of kappa-B,which
R4297 T5680 T5686 arg1Of kappa-B,dissociates
R4298 T5682 T5681 arg2Of IκB,(
R4299 T5683 T5681 arg3Of ),(
R43 T174 T175 arg1Of pathogenesis,of
R4300 T5687 T5686 arg2Of IκB,dissociates
R4301 T5687 T5688 arg1Of IκB,with
R4302 T5689 T5688 arg2Of NF-kappa-B,with
R4303 T5689 T5690 arg1Of NF-kappa-B,(
R4304 T5691 T5690 arg2Of NFκB,(
R4305 T5692 T5690 arg3Of ),(
R4306 T5695 T5696 arg1Of NFκB,translocates
R4307 T5695 T5701 arg1Of NFκB,activates
R4308 T5695 T5703 arg1Of NFκB,regulates
R4309 T5696 T5697 arg1Of translocates,into
R4310 T5696 T5700 arg1Of translocates,and
R4311 T5699 T5697 arg2Of nucleus,into
R4312 T5699 T5698 arg1Of nucleus,the
R4313 T5700 T5693 arg1Of and,Then
R4314 T5700 T5694 arg1Of and,","
R4315 T5701 T5702 arg1Of activates,and
R4316 T5702 T5700 arg2Of and,and
R4317 T5703 T5702 arg2Of regulates,and
R4318 T5705 T5701 arg2Of transcription,activates
R4319 T5705 T5703 arg2Of transcription,regulates
R4320 T5705 T5704 arg1Of transcription,the
R4321 T5705 T5706 arg1Of transcription,of
R4322 T5707 T5706 arg2Of genes,of
R4323 T5707 T5708 arg2Of genes,related
R4324 T5708 T5709 arg1Of related,to
R4325 T5711 T5709 arg2Of responses,to
R4326 T5711 T5710 arg1Of responses,inflammatory
R4327 T5713 T5712 arg1Of detectd,To
R4328 T5715 T5713 arg2Of activation,detectd
R4329 T5715 T5714 arg1Of activation,the
R4330 T5715 T5716 arg1Of activation,of
R4331 T5719 T5716 arg2Of signaling,of
R4332 T5719 T5717 arg1Of signaling,TLR4-mediated
R4333 T5719 T5718 arg1Of signaling,NFκB
R4334 T5722 T5721 arg1Of phosphorylation,the
R4335 T5722 T5723 arg1Of phosphorylation,of
R4336 T5722 T5734 arg1Of phosphorylation,were
R4337 T5722 T5735 arg2Of phosphorylation,measured
R4338 T5724 T5723 arg2Of inhibitor,of
R4339 T5724 T5725 arg1Of inhibitor,of
R4340 T5726 T5727 arg1Of kappa-B,(
R4341 T5726 T5730 arg1Of kappa-B,and
R4342 T5728 T5727 arg2Of p-IκB,(
R4343 T5729 T5727 arg3Of ),(
R4344 T5730 T5725 arg2Of and,of
R4345 T5731 T5730 arg2Of activity,and
R4346 T5731 T5732 arg1Of activity,of
R4347 T5733 T5732 arg2Of NFκB,of
R4348 T5735 T5712 modOf measured,To
R4349 T5735 T5720 arg1Of measured,","
R4350 T5735 T5734 arg2Of measured,were
R4351 T5737 T5735 arg1Of methods,measured
R4352 T5737 T5736 arg2Of methods,by
R4353 T5737 T5738 arg1Of methods,of
R4354 T5740 T5739 arg1Of Blots,Western
R4355 T5740 T5741 arg1Of Blots,and
R4356 T5741 T5738 arg2Of and,of
R4357 T5742 T5741 arg2Of EMSA,and
R4358 T5743 T5744 arg1Of Results,showed
R4359 T5747 T5746 arg1Of p-IκB,the
R4360 T5747 T5748 arg1Of p-IκB,increased
R4361 T5748 T5744 arg2Of increased,showed
R4362 T5748 T5745 arg1Of increased,that
R4363 T5748 T5749 arg1Of increased,at
R4364 T5748 T5751 arg1Of increased,after
R4365 T5750 T5749 arg2Of 6 hours,at
R4366 T5752 T5753 arg1Of ICH,(
R4367 T5752 T5759 arg1Of ICH,peaked
R4368 T5752 T5767 arg1Of ICH,maintained
R4369 T5754 T5753 arg2Of P,(
R4370 T5754 T5755 arg1Of P,<
R4371 T5755 T5756 arg1Of <,.05
R4372 T5757 T5753 arg3Of ),(
R4373 T5759 T5760 arg1Of peaked,on
R4374 T5759 T5763 arg1Of peaked,after
R4375 T5759 T5766 arg1Of peaked,and
R4376 T5762 T5760 arg2Of days,on
R4377 T5762 T5761 arg1Of days,3
R4378 T5764 T5763 arg2Of ICH,after
R4379 T5766 T5751 arg2Of and,after
R4380 T5766 T5758 arg1Of and,","
R4381 T5766 T5765 arg1Of and,","
R4382 T5767 T5766 arg2Of maintained,and
R4383 T5767 T5771 arg1Of maintained,on
R4384 T5770 T5767 arg2Of level,maintained
R4385 T5770 T5768 arg1Of level,a
R4386 T5770 T5769 arg1Of level,high
R4387 T5773 T5771 arg2Of days,on
R4388 T5773 T5772 arg1Of days,7
R4389 T5773 T5774 arg1Of days,after
R4390 T5773 T5776 arg1Of days,(
R4391 T5775 T5774 arg2Of ICH,after
R4392 T5777 T5776 arg2Of P,(
R4393 T5777 T5778 arg1Of P,<
R4394 T5777 T5780 arg1Of P,","
R4395 T5778 T5779 arg1Of <,.05
R4396 T5781 T5780 arg2Of Figure,","
R4397 T5781 T5782 arg1Of Figure,5
R4398 T5783 T5776 arg3Of ),(
R4399 T5785 T5784 arg2Of expected,As
R44 T177 T175 arg2Of hemorrhage,of
R4400 T5788 T5787 arg1Of activity,the
R4401 T5788 T5789 arg1Of activity,of
R4402 T5788 T5791 arg1Of activity,was
R4403 T5788 T5793 arg2Of activity,increased
R4404 T5790 T5789 arg2Of NFκB,of
R4405 T5793 T5784 arg1Of increased,As
R4406 T5793 T5786 arg1Of increased,","
R4407 T5793 T5791 arg2Of increased,was
R4408 T5793 T5792 arg1Of increased,also
R4409 T5793 T5794 arg1Of increased,in
R4410 T5793 T5798 arg1Of increased,as
R4411 T5797 T5794 arg2Of manner,in
R4412 T5797 T5795 arg1Of manner,the
R4413 T5797 T5796 arg1Of manner,same
R4414 T5799 T5798 arg2Of that,as
R4415 T5799 T5800 arg1Of that,of
R4416 T5802 T5800 arg2Of p-IκB,of
R4417 T5802 T5801 arg1Of p-IκB,the
R4418 T5802 T5803 arg1Of p-IκB,(
R4419 T5804 T5803 arg2Of Figure,(
R4420 T5804 T5805 arg1Of Figure,4
R4421 T5806 T5803 arg3Of ),(
R45 T177 T176 arg1Of hemorrhage,Intracerebral
R46 T177 T178 arg1Of hemorrhage,(
R47 T179 T178 arg2Of ICH,(
R4719 T6548 T6547 arg1Of hemorrhage,Intra-cerebral
R4720 T6548 T6549 arg1Of hemorrhage,(
R4721 T6548 T6552 arg1Of hemorrhage,represents
R4722 T6548 T6560 arg1Of hemorrhage,occurs
R4723 T6550 T6549 arg2Of ICH,(
R4724 T6551 T6549 arg3Of ),(
R4725 T6552 T6559 arg1Of represents,and
R4726 T6554 T6552 arg2Of %,represents
R4727 T6554 T6553 arg1Of %,10–15
R4728 T6554 T6555 arg1Of %,of
R4729 T6557 T6555 arg2Of strokes,of
R4730 T6557 T6556 arg1Of strokes,all
R4731 T6559 T6558 arg1Of and,","
R4732 T6560 T6559 arg2Of occurs,and
R4733 T6560 T6561 arg1Of occurs,with
R4734 T6560 T6564 arg1Of occurs,as
R4735 T6563 T6561 arg2Of frequency,with
R4736 T6563 T6562 arg1Of frequency,increasing
R4737 T6566 T6564 arg2Of complication,as
R4738 T6566 T6565 arg1Of complication,a
R4739 T6566 T6567 arg1Of complication,of
R4740 T6570 T6567 arg2Of treatment,of
R4741 T6570 T6568 arg1Of treatment,the
R4742 T6570 T6569 arg1Of treatment,thrombolytic
R4743 T6570 T6571 arg1Of treatment,of
R4744 T6570 T6574 arg1Of treatment,[
R4745 T6573 T6571 arg2Of stroke,of
R4746 T6573 T6572 arg1Of stroke,ischemic
R4747 T6575 T6574 arg2Of 1,[
R4748 T6576 T6574 arg3Of ],[
R4749 T6578 T6577 arg1Of mortality,The
R4750 T6578 T6579 arg1Of mortality,of
R4751 T6578 T6581 arg1Of mortality,is
R4752 T6578 T6582 arg1Of mortality,higher
R4753 T6580 T6579 arg2Of ICH,of
R4754 T6582 T6581 arg2Of higher,is
R4755 T6582 T6583 arg1Of higher,than
R4756 T6584 T6583 arg2Of that,than
R4757 T6584 T6585 arg1Of that,of
R4758 T6587 T6585 arg2Of stroke,of
R4759 T6587 T6586 arg1Of stroke,ischemic
R4760 T6589 T6588 arg1Of 31,Only
R4761 T6590 T6589 arg1Of %,31
R4762 T6590 T6591 arg1Of %,are
R4763 T6590 T6593 arg1Of %,independent
R4764 T6591 T6592 arg1Of are,functionally
R4765 T6591 T6594 arg1Of are,at
R4766 T6593 T6591 arg2Of independent,are
R4767 T6596 T6594 arg2Of months,at
R4768 T6596 T6595 arg1Of months,3
R4769 T6598 T6597 arg1Of 38,Only
R4770 T6599 T6598 arg1Of %,38
R4771 T6599 T6600 arg1Of %,of
R4772 T6599 T6603 arg1Of %,survive
R4773 T6602 T6600 arg2Of patients,of
R4774 T6602 T6601 arg1Of patients,the
R4775 T6603 T6607 arg1Of survive,[
R4776 T6606 T6603 arg2Of year,survive
R4777 T6606 T6604 arg1Of year,the
R4778 T6606 T6605 arg1Of year,1st
R4779 T6608 T6607 arg2Of 10,[
R4780 T6609 T6607 arg3Of ],[
R4781 T6613 T6612 arg1Of method,the
R4782 T6613 T6614 arg1Of method,for
R4783 T6613 T6627 arg1Of method,are
R4784 T6613 T6629 arg1Of method,effective
R4785 T6615 T6616 arg1Of treatment,of
R4786 T6615 T6619 arg1Of treatment,and
R4787 T6618 T6616 arg2Of disease,of
R4788 T6618 T6617 arg1Of disease,this
R4789 T6619 T6614 arg2Of and,for
R4790 T6619 T6625 arg1Of and,after
R4791 T6620 T6619 arg2Of protection,and
R4792 T6620 T6621 arg1Of protection,of
R4793 T6624 T6621 arg2Of tissue,of
R4794 T6624 T6622 arg1Of tissue,the
R4795 T6624 T6623 arg1Of tissue,brain
R4796 T6626 T6625 arg2Of ICH,after
R4797 T6627 T6610 arg1Of are,Unfortunately
R4798 T6627 T6611 arg1Of are,","
R4799 T6627 T6628 arg1Of are,not
R48 T180 T178 arg3Of ),(
R4800 T6629 T6627 arg2Of effective,are
R4801 T6631 T6630 arg1Of effect,Mass
R4802 T6631 T6632 arg1Of effect,","
R4803 T6632 T6635 arg1Of ",",and
R4804 T6633 T6632 arg2Of ischemia,","
R4805 T6635 T6634 arg1Of and,","
R4806 T6635 T6637 arg1Of and,of
R4807 T6635 T6640 arg1Of and,after
R4808 T6635 T6642 arg1Of and,induce
R4809 T6636 T6635 arg2Of toxicity,and
R4810 T6639 T6637 arg2Of components,of
R4811 T6639 T6638 arg1Of components,blood
R4812 T6641 T6640 arg2Of ICH,after
R4813 T6645 T6642 arg2Of damage,induce
R4814 T6645 T6643 arg1Of damage,brain
R4815 T6645 T6644 arg1Of damage,tissue
R4816 T6647 T6646 arg2Of addition,In
R4817 T6649 T6650 arg1Of there,is
R4818 T6650 T6646 arg1Of is,In
R4819 T6650 T6648 arg1Of is,","
R4820 T6652 T6650 arg2Of evidence,is
R4821 T6652 T6651 arg1Of evidence,increasing
R4822 T6655 T6654 arg1Of processes,inflammatory
R4823 T6655 T6656 arg1Of processes,are
R4824 T6655 T6657 arg2Of processes,involved
R4825 T6657 T6652 arg2Of involved,evidence
R4826 T6657 T6653 arg1Of involved,that
R4827 T6657 T6656 arg2Of involved,are
R4828 T6657 T6658 arg1Of involved,in
R4829 T6660 T6658 arg2Of events,in
R4830 T6660 T6659 arg1Of events,cerebrovascular
R4831 T6662 T6661 arg2Of ICH,After
R4832 T6665 T6664 arg1Of mediators,inflammatory
R4833 T6665 T6666 arg1Of mediators,from
R4834 T6665 T6669 arg1Of mediators,might
R4835 T6665 T6670 arg1Of mediators,enter
R4836 T6665 T6675 arg1Of mediators,induce
R4837 T6668 T6666 arg2Of blood,from
R4838 T6668 T6667 arg1Of blood,the
R4839 T6670 T6671 arg1Of enter,to
R4840 T6670 T6674 arg1Of enter,and
R4841 T6673 T6671 arg2Of brain,to
R4842 T6673 T6672 arg1Of brain,the
R4843 T6674 T6669 arg2Of and,might
R4844 T6674 T6679 arg1Of and,and
R4845 T6675 T6674 arg2Of induce,and
R4846 T6678 T6675 arg2Of reaction,induce
R4847 T6678 T6676 arg1Of reaction,an
R4848 T6678 T6677 arg1Of reaction,inflammatory
R4849 T6679 T6661 arg1Of and,After
R4850 T6679 T6663 arg1Of and,","
R4851 T6682 T6680 arg1Of cells,the
R4852 T6682 T6681 arg1Of cells,brain
R4853 T6682 T6683 arg1Of cells,itself
R4854 T6682 T6684 arg1Of cells,are
R4855 T6682 T6686 arg1Of cells,capable
R4856 T6682 T6688 arg1Of cells,producing
R4857 T6684 T6679 arg2Of are,and
R4858 T6684 T6685 arg1Of are,also
R4859 T6686 T6684 arg2Of capable,are
R4860 T6686 T6687 arg1Of capable,of
R4861 T6688 T6687 arg2Of producing,of
R4862 T6688 T6693 arg1Of producing,[
R4863 T6689 T6688 arg2Of many,producing
R4864 T6689 T6690 arg1Of many,of
R4865 T6692 T6690 arg2Of agents,of
R4866 T6692 T6691 arg1Of agents,these
R4867 T6694 T6693 arg2Of 11,[
R4868 T6695 T6693 arg3Of ],[
R4869 T6698 T6696 arg1Of responses,The
R4870 T6698 T6697 arg1Of responses,inflammatory
R4871 T6698 T6699 arg1Of responses,are
R4872 T6698 T6700 arg1Of responses,responsible
R4873 T6700 T6699 arg2Of responsible,are
R4874 T6700 T6701 arg1Of responsible,for
R4875 T6704 T6703 arg1Of induced,ICH
R4876 T6706 T6701 arg2Of injury,for
R4877 T6706 T6702 arg1Of injury,the
R4878 T6706 T6704 arg1Of injury,induced
R4879 T6706 T6705 arg1Of injury,brain
R4880 T6706 T6707 arg1Of injury,","
R4881 T6706 T6708 arg1Of injury,which
R4882 T6706 T6709 arg1Of injury,could
R4883 T6706 T6710 arg1Of injury,provide
R4884 T6710 T6709 arg2Of provide,could
R4885 T6712 T6711 arg1Of therapeutic,new
R4886 T6713 T6710 arg2Of targets,provide
R4887 T6713 T6712 arg1Of targets,therapeutic
R4888 T6713 T6714 arg1Of targets,for
R4889 T6715 T6714 arg2Of ICH,for
R4890 T6717 T6716 arg1Of constituents,Various
R4891 T6717 T6718 arg1Of constituents,of
R4892 T6717 T6722 arg1Of constituents,","
R4893 T6717 T6723 arg1Of constituents,including
R4894 T6717 T6733 arg1Of constituents,and
R4895 T6721 T6718 arg2Of response,of
R4896 T6721 T6719 arg1Of response,the
R4897 T6721 T6720 arg1Of response,inflammatory
R4898 T6725 T6724 arg1Of molecules,adhesion
R4899 T6725 T6726 arg1Of molecules,","
R49 T183 T181 arg1Of 4-,Toll-like
R4900 T6726 T6728 arg1Of ",",","
R4901 T6727 T6726 arg2Of cytokines,","
R4902 T6728 T6730 arg1Of ",",","
R4903 T6729 T6728 arg2Of leukocytes,","
R4904 T6730 T6723 arg2Of ",",including
R4905 T6731 T6730 arg2Of immunoglobulins,","
R4906 T6733 T6732 arg1Of and,","
R4907 T6733 T6736 arg1Of and,may
R4908 T6733 T6737 arg1Of and,be
R4909 T6733 T6738 arg1Of and,important
R4910 T6734 T6733 arg2Of complement,and
R4911 T6737 T6735 arg1Of be,","
R4912 T6737 T6736 arg2Of be,may
R4913 T6737 T6739 arg1Of be,in
R4914 T6738 T6737 arg2Of important,be
R4915 T6741 T6739 arg2Of pathogenesis,in
R4916 T6741 T6740 arg1Of pathogenesis,the
R4917 T6741 T6742 arg1Of pathogenesis,of
R4918 T6743 T6742 arg2Of ICH,of
R4919 T6746 T6760 arg1Of how,is
R4920 T6746 T6761 arg1Of how,unclear
R4921 T6749 T6747 arg1Of responses,the
R4922 T6749 T6748 arg1Of responses,inflammatory
R4923 T6749 T6750 arg1Of responses,is
R4924 T6749 T6751 arg2Of responses,activated
R4925 T6749 T6753 arg2Of responses,regulated
R4926 T6751 T6752 arg1Of activated,and
R4927 T6752 T6746 arg1Of and,how
R4928 T6752 T6750 arg2Of and,is
R4929 T6752 T6754 arg1Of and,in
R4930 T6753 T6752 arg2Of regulated,and
R4931 T6757 T6754 arg2Of tissue,in
R4932 T6757 T6755 arg1Of tissue,the
R4933 T6757 T6756 arg1Of tissue,brain
R4934 T6757 T6758 arg1Of tissue,after
R4935 T6759 T6758 arg2Of ICH,after
R4936 T6760 T6744 arg1Of is,However
R4937 T6760 T6745 arg1Of is,","
R4938 T6761 T6760 arg2Of unclear,is
R4939 T6765 T6762 arg1Of factor-kappa-B,Transcription
R4940 T6765 T6763 arg1Of factor-kappa-B,factor
R4941 T6765 T6764 arg1Of factor-kappa-B,nuclear
R4942 T6765 T6766 arg1Of factor-kappa-B,(
R4943 T6765 T6769 arg1Of factor-kappa-B,is
R4944 T6767 T6766 arg2Of NFκB,(
R4945 T6768 T6766 arg3Of ),(
R4946 T6774 T6769 arg2Of factor,is
R4947 T6774 T6770 arg1Of factor,an
R4948 T6774 T6771 arg1Of factor,important
R4949 T6774 T6772 arg1Of factor,nuclear
R4950 T6774 T6773 arg1Of factor,transcription
R4951 T6774 T6775 arg1Of factor,","
R4952 T6774 T6776 arg1Of factor,which
R4953 T6774 T6777 arg1Of factor,initiates
R4954 T6774 T6794 arg1Of factor,plays
R4955 T6774 T6799 arg1Of factor,regulating
R4956 T6777 T6792 arg1Of initiates,and
R4957 T6778 T6777 arg2Of transcription,initiates
R4958 T6778 T6779 arg1Of transcription,of
R4959 T6780 T6779 arg2Of genes,of
R4960 T6780 T6781 arg2Of genes,associated
R4961 T6781 T6782 arg1Of associated,with
R4962 T6781 T6787 arg1Of associated,[
R4963 T6784 T6783 arg1Of responses,immune
R4964 T6784 T6785 arg1Of responses,and
R4965 T6785 T6782 arg2Of and,with
R4966 T6786 T6785 arg2Of inflammation,and
R4967 T6788 T6789 arg1Of 12,","
R4968 T6789 T6787 arg2Of ",",[
R4969 T6790 T6789 arg2Of 13,","
R4970 T6791 T6787 arg3Of ],[
R4971 T6794 T6792 arg2Of plays,and
R4972 T6794 T6793 arg1Of plays,also
R4973 T6794 T6798 arg1Of plays,in
R4974 T6797 T6794 arg2Of role,plays
R4975 T6797 T6795 arg1Of role,a
R4976 T6797 T6796 arg1Of role,key
R4977 T6799 T6798 arg2Of regulating,in
R4978 T6799 T6801 arg1Of regulating,in
R4979 T6800 T6799 arg2Of inflammation,regulating
R4980 T6803 T6801 arg2Of pathologies,in
R4981 T6803 T6802 arg1Of pathologies,brain
R4982 T6804 T6805 arg1Of It,has
R4983 T6804 T6806 arg1Of It,been
R4984 T6804 T6807 arg2Of It,reported
R4985 T6807 T6805 arg2Of reported,has
R4986 T6807 T6806 arg2Of reported,been
R4987 T6809 T6810 arg1Of NFκB,increased
R4988 T6810 T6807 arg3Of increased,reported
R4989 T6810 T6808 arg1Of increased,that
R4990 T6810 T6811 arg1Of increased,in
R4991 T6813 T6811 arg2Of region,in
R4992 T6813 T6812 arg1Of region,the
R4993 T6813 T6814 arg1Of region,of
R4994 T6813 T6816 arg1Of region,after
R4995 T6815 T6814 arg2Of perihematoma,of
R4996 T6817 T6816 arg2Of ICH,after
R4997 T6817 T6818 arg1Of ICH,[
R4998 T6819 T6818 arg2Of 14,[
R4999 T6820 T6818 arg3Of ],[
R50 T183 T182 arg1Of 4-,receptor
R5000 T6822 T6821 arg1Of activation,NFκB
R5001 T6822 T6823 arg1Of activation,occurs
R5002 T6822 T6827 arg1Of activation,persists
R5003 T6823 T6824 arg1Of occurs,within
R5004 T6823 T6826 arg1Of occurs,and
R5005 T6825 T6824 arg2Of minutes,within
R5006 T6827 T6826 arg2Of persists,and
R5007 T6827 T6828 arg1Of persists,for
R5008 T6830 T6829 arg1Of least,at
R5009 T6832 T6828 arg2Of week,for
R5010 T6832 T6830 arg1Of week,least
R5011 T6832 T6831 arg1Of week,a
R5012 T6832 T6833 arg1Of week,in
R5013 T6832 T6837 arg1Of week,","
R5014 T6832 T6838 arg1Of week,which
R5015 T6832 T6839 arg1Of week,is
R5016 T6832 T6840 arg2Of week,associated
R5017 T6833 T6835 arg1Of in,to
R5018 T6834 T6833 arg2Of response,in
R5019 T6836 T6833 arg3Of ICH,in
R5020 T6840 T6839 arg2Of associated,is
R5021 T6840 T6841 arg1Of associated,with
R5022 T6843 T6841 arg2Of expression,with
R5023 T6843 T6842 arg1Of expression,the
R5024 T6843 T6844 arg1Of expression,of
R5025 T6847 T6844 arg2Of genes,of
R5026 T6847 T6845 arg2Of genes,selected
R5027 T6847 T6846 arg1Of genes,target
R5028 T6847 T6848 arg1Of genes,[
R5029 T6849 T6848 arg2Of 15,[
R5030 T6850 T6848 arg3Of ],[
R5031 T6851 T6852 arg1Of Activation,of
R5032 T6851 T6854 arg1Of Activation,initiates
R5033 T6851 T6858 arg1Of Activation,contributes
R5034 T6853 T6852 arg2Of NFκB,of
R5035 T6854 T6857 arg1Of initiates,and
R5036 T6856 T6854 arg2Of responses,initiates
R5037 T6856 T6855 arg1Of responses,inflammatory
R5038 T6857 T6868 arg1Of and,[
R5039 T6858 T6857 arg2Of contributes,and
R5040 T6858 T6859 arg1Of contributes,to
R5041 T6858 T6866 arg1Of contributes,after
R5042 T6861 T6859 arg2Of pathobiology,to
R5043 T6861 T6860 arg1Of pathobiology,the
R5044 T6861 T6862 arg1Of pathobiology,of
R5045 T6865 T6862 arg2Of death,of
R5046 T6865 T6863 arg1Of death,perilesional
R5047 T6865 T6864 arg1Of death,cell
R5048 T6867 T6866 arg2Of ICH,after
R5049 T6869 T6868 arg2Of 16,[
R5050 T6870 T6868 arg3Of ],[
R5051 T6871 T6872 arg1Of Inhibition,of
R5052 T6871 T6875 arg1Of Inhibition,has
R5053 T6871 T6876 arg1Of Inhibition,been
R5054 T6871 T6877 arg2Of Inhibition,shown
R5055 T6871 T6879 arg1Of Inhibition,have
R5056 T6874 T6872 arg2Of activity,of
R5057 T6874 T6873 arg1Of activity,NFκB
R5058 T6877 T6875 arg2Of shown,has
R5059 T6877 T6876 arg2Of shown,been
R5060 T6879 T6877 arg3Of have,shown
R5061 T6879 T6878 arg1Of have,to
R5062 T6882 T6879 arg2Of effect,have
R5063 T6882 T6880 arg1Of effect,a
R5064 T6882 T6881 arg1Of effect,therapeutic
R5065 T6882 T6883 arg1Of effect,on
R5066 T6882 T6886 arg1Of effect,","
R5067 T6882 T6888 arg1Of effect,as
R5068 T6885 T6883 arg2Of ICH,on
R5069 T6885 T6884 arg1Of ICH,experimental
R5070 T6888 T6887 arg1Of as,such
R5071 T6890 T6889 arg1Of inflammation,reduce
R5072 T6890 T6891 arg1Of inflammation,","
R5073 T6891 T6895 arg1Of ",",and
R5074 T6893 T6891 arg2Of dysfunction,","
R5075 T6893 T6892 arg1Of dysfunction,behavioral
R5076 T6895 T6888 arg2Of and,as
R5077 T6895 T6894 arg1Of and,","
R5078 T6897 T6895 arg2Of damage,and
R5079 T6897 T6896 arg1Of damage,neuronal
R5080 T6897 T6898 arg2Of damage,produced
R5081 T6898 T6901 arg1Of produced,[
R5082 T6900 T6898 arg1Of ICH,produced
R5083 T6900 T6899 arg2Of ICH,by
R5084 T6902 T6901 arg2Of 17,[
R5085 T6903 T6901 arg3Of ],[
R5086 T6905 T6904 arg1Of knowledge,The
R5087 T6905 T6906 arg1Of knowledge,about
R5088 T6905 T6917 arg1Of knowledge,is
R5089 T6905 T6918 arg1Of knowledge,critical
R5090 T6907 T6906 arg2Of how,about
R5091 T6908 T6909 arg1Of NFκB,is
R5092 T6908 T6910 arg2Of NFκB,activated
R5093 T6910 T6907 arg1Of activated,how
R5094 T6910 T6909 arg2Of activated,is
R5095 T6910 T6911 arg1Of activated,in
R5096 T6913 T6911 arg2Of brain,in
R5097 T6913 T6912 arg1Of brain,the
R5098 T6913 T6914 arg2Of brain,subjected
R5099 T6914 T6915 arg1Of subjected,to
R51 T183 T184 arg1Of 4-,(
R5100 T6916 T6915 arg2Of ICH,to
R5101 T6918 T6917 arg2Of critical,is
R5102 T6918 T6919 arg1Of critical,for
R5103 T6920 T6919 arg2Of seeking,for
R5104 T6924 T6920 arg2Of method,seeking
R5105 T6924 T6921 arg1Of method,a
R5106 T6924 T6922 arg1Of method,new
R5107 T6924 T6923 arg1Of method,neuroprotective
R5108 T6924 T6925 arg1Of method,for
R5109 T6926 T6925 arg2Of ICH,for
R5110 T6928 T6927 arg1Of receptors,Toll-like
R5111 T6928 T6929 arg1Of receptors,(
R5112 T6928 T6932 arg1Of receptors,are
R5113 T6928 T6940 arg1Of receptors,play
R5114 T6930 T6929 arg2Of TLRs,(
R5115 T6931 T6929 arg3Of ),(
R5116 T6932 T6939 arg1Of are,and
R5117 T6934 T6932 arg2Of family,are
R5118 T6934 T6933 arg1Of family,a
R5119 T6934 T6935 arg1Of family,of
R5120 T6938 T6935 arg2Of molecules,of
R5121 T6938 T6936 arg1Of molecules,signal
R5122 T6938 T6937 arg1Of molecules,transduction
R5123 T6940 T6939 arg2Of play,and
R5124 T6940 T6944 arg1Of play,in
R5125 T6943 T6940 arg2Of role,play
R5126 T6943 T6941 arg1Of role,a
R5127 T6943 T6942 arg1Of role,critical
R5128 T6946 T6944 arg2Of induction,in
R5129 T6946 T6945 arg1Of induction,the
R5130 T6946 T6947 arg1Of induction,of
R5131 T6948 T6949 arg1Of innate,and
R5132 T6950 T6949 arg2Of adaptive,and
R5133 T6951 T6947 arg2Of immunity,of
R5134 T6951 T6948 arg1Of immunity,innate
R5135 T6951 T6950 arg1Of immunity,adaptive
R5136 T6951 T6952 arg1Of immunity,[
R5137 T6953 T6952 arg2Of 4,[
R5138 T6954 T6952 arg3Of ],[
R5139 T6957 T6955 arg1Of pathways,TLR-mediated
R5140 T6957 T6956 arg1Of pathways,signaling
R5141 T6957 T6959 arg1Of pathways,stimulate
R5142 T6959 T6958 arg1Of stimulate,mainly
R5143 T6959 T6964 arg1Of stimulate,[
R5144 T6961 T6959 arg2Of activation,stimulate
R5145 T6961 T6960 arg1Of activation,the
R5146 T6961 T6962 arg1Of activation,of
R5147 T6963 T6962 arg2Of NFκB,of
R5148 T6965 T6964 arg2Of 12,[
R5149 T6965 T6966 arg1Of 12,","
R5150 T6967 T6966 arg2Of 13,","
R5151 T6968 T6964 arg3Of ],[
R5152 T6969 T6970 arg1Of TLR4,","
R5153 T6969 T6977 arg1Of TLR4,has
R5154 T6969 T6978 arg1Of TLR4,been
R5155 T6969 T6979 arg2Of TLR4,reported
R5156 T6969 T6981 arg1Of TLR4,be
R5157 T6969 T6982 arg2Of TLR4,involved
R5158 T6974 T6970 arg2Of TLR,","
R5159 T6974 T6971 arg1Of TLR,the
R5160 T6974 T6972 arg1Of TLR,first
R5161 T6974 T6973 arg1Of TLR,mammalian
R5162 T6974 T6975 arg2Of TLR,recognized
R5163 T6979 T6976 arg1Of reported,","
R5164 T6979 T6977 arg2Of reported,has
R5165 T6979 T6978 arg2Of reported,been
R5166 T6982 T6979 arg3Of involved,reported
R5167 T6982 T6980 arg1Of involved,to
R5168 T6982 T6981 arg2Of involved,be
R5169 T6982 T6983 arg1Of involved,in
R5170 T6986 T6985 arg1Of nervous,central
R5171 T6986 T6987 arg1Of nervous,(
R5172 T6988 T6987 arg2Of CNS,(
R5173 T6989 T6987 arg3Of ),(
R5174 T6991 T6983 arg2Of diseases,in
R5175 T6991 T6984 arg1Of diseases,several
R5176 T6991 T6986 arg1Of diseases,nervous
R5177 T6991 T6990 arg1Of diseases,system
R5178 T6991 T6992 arg1Of diseases,","
R5179 T6991 T6994 arg1Of diseases,as
R5180 T6994 T6993 arg1Of as,such
R5181 T6995 T6996 arg1Of inflammatory,or
R5182 T6997 T6996 arg2Of autoimmune,or
R5183 T6999 T6995 arg1Of diseases,inflammatory
R5184 T6999 T6997 arg1Of diseases,autoimmune
R5185 T6999 T6998 arg1Of diseases,CNS
R5186 T6999 T7000 arg1Of diseases,and
R5187 T7000 T6994 arg2Of and,as
R5188 T7003 T7000 arg2Of injury,and
R5189 T7003 T7001 arg1Of injury,cerebral
R5190 T7003 T7002 arg1Of injury,ischemic
R5191 T7003 T7004 arg1Of injury,[
R5192 T7005 T7004 arg2Of 7,[
R5193 T7005 T7006 arg1Of 7,","
R5194 T7007 T7006 arg2Of 8,","
R5195 T7008 T7004 arg3Of ],[
R5196 T7011 T7010 arg1Of reports,previous
R5197 T7011 T7012 arg1Of reports,indicated
R5198 T7012 T7009 arg2Of indicated,Although
R5199 T7015 T7014 arg1Of activation,the
R52 T185 T184 arg2Of TLR4-,(
R5200 T7015 T7016 arg1Of activation,of
R5201 T7015 T7018 arg1Of activation,was
R5202 T7015 T7019 arg2Of activation,attributed
R5203 T7017 T7016 arg2Of NFκB,of
R5204 T7019 T7012 arg2Of attributed,indicated
R5205 T7019 T7013 arg1Of attributed,that
R5206 T7019 T7018 arg2Of attributed,was
R5207 T7019 T7020 arg1Of attributed,to
R5208 T7023 T7024 arg1Of stress,or
R5209 T7025 T7024 arg2Of glutamate,or
R5210 T7027 T7020 arg2Of activation,to
R5211 T7027 T7021 arg1Of activation,the
R5212 T7027 T7022 arg1Of activation,oxidative
R5213 T7027 T7023 arg1Of activation,stress
R5214 T7027 T7025 arg1Of activation,glutamate
R5215 T7027 T7026 arg1Of activation,receptor
R5216 T7027 T7028 arg2Of activation,induced
R5217 T7032 T7030 arg1Of cells,red
R5218 T7032 T7031 arg1Of cells,blood
R5219 T7032 T7033 arg1Of cells,and/or
R5220 T7033 T7028 arg1Of and/or,induced
R5221 T7033 T7029 arg2Of and/or,by
R5222 T7035 T7033 arg2Of constituents,and/or
R5223 T7035 T7034 arg1Of constituents,plasma
R5224 T7035 T7036 arg1Of constituents,[
R5225 T7037 T7036 arg2Of 17,[
R5226 T7038 T7036 arg3Of ],[
R5227 T7041 T7040 arg1Of few,very
R5228 T7042 T7041 arg1Of studies,few
R5229 T7042 T7043 arg1Of studies,have
R5230 T7042 T7044 arg1Of studies,been
R5231 T7042 T7045 arg2Of studies,directed
R5232 T7042 T7047 arg1Of studies,investigate
R5233 T7045 T7009 arg1Of directed,Although
R5234 T7045 T7039 arg1Of directed,","
R5235 T7045 T7043 arg2Of directed,have
R5236 T7045 T7044 arg2Of directed,been
R5237 T7047 T7045 arg3Of investigate,directed
R5238 T7047 T7046 arg1Of investigate,to
R5239 T7049 T7048 arg1Of role,the
R5240 T7049 T7050 arg1Of role,and
R5241 T7050 T7047 arg2Of and,investigate
R5242 T7052 T7050 arg2Of relationship,and
R5243 T7052 T7051 arg1Of relationship,the
R5244 T7052 T7053 arg1Of relationship,between
R5245 T7056 T7057 arg1Of signaling,and
R5246 T7057 T7053 arg2Of and,between
R5247 T7057 T7054 arg1Of and,TLR4-mediated
R5248 T7057 T7055 arg1Of and,NFκB
R5249 T7058 T7057 arg2Of ICH,and
R5250 T7062 T7059 arg2Of study,In
R5251 T7062 T7060 arg1Of study,the
R5252 T7062 T7061 arg1Of study,present
R5253 T7064 T7065 arg1Of we,established
R5254 T7064 T7073 arg1Of we,detected
R5255 T7065 T7072 arg1Of established,and
R5256 T7068 T7065 arg2Of model,established
R5257 T7068 T7066 arg1Of model,the
R5258 T7068 T7067 arg1Of model,rat
R5259 T7068 T7069 arg1Of model,of
R5260 T7071 T7069 arg2Of ICH,of
R5261 T7071 T7070 arg1Of ICH,experimental
R5262 T7072 T7059 arg1Of and,In
R5263 T7072 T7063 arg1Of and,","
R5264 T7073 T7072 arg2Of detected,and
R5265 T7076 T7077 arg1Of mRNA,and
R5266 T7077 T7073 arg2Of and,detected
R5267 T7077 T7074 arg1Of and,the
R5268 T7077 T7075 arg1Of and,TLR4
R5269 T7078 T7077 arg2Of protein,and
R5270 T7080 T7079 arg1Of data,Our
R5271 T7080 T7081 arg1Of data,showed
R5272 T7083 T7084 arg1Of transcription,of
R5273 T7083 T7088 arg1Of transcription,as
R5274 T7085 T7084 arg2Of TLR4,of
R5275 T7088 T7086 arg1Of as,as
R5276 T7088 T7087 arg1Of as,well
R5277 T7088 T7097 arg2Of as,elevated
R5278 T7090 T7088 arg2Of expression,as
R5279 T7090 T7089 arg1Of expression,the
R5280 T7090 T7091 arg1Of expression,of
R5281 T7093 T7091 arg2Of protein,of
R5282 T7093 T7092 arg1Of protein,TLR4
R5283 T7093 T7094 arg1Of protein,after
R5284 T7095 T7094 arg2Of ICH,after
R5285 T7097 T7081 arg2Of elevated,showed
R5286 T7097 T7082 arg1Of elevated,that
R5287 T7097 T7096 arg1Of elevated,significantly
R5288 T7097 T7098 arg1Of elevated,in
R5289 T7100 T7098 arg2Of tissue,in
R5290 T7100 T7099 arg1Of tissue,brain
R5291 T7102 T7101 arg1Of changes,These
R5292 T7102 T7103 arg1Of changes,started
R5293 T7102 T7114 arg1Of changes,maintained
R5294 T7103 T7105 arg1Of started,early
R5295 T7103 T7109 arg1Of started,after
R5296 T7103 T7113 arg1Of started,and
R5297 T7105 T7104 arg1Of early,as
R5298 T7105 T7106 arg1Of early,as
R5299 T7108 T7106 arg2Of hours,as
R53 T186 T184 arg3Of ),(
R5300 T7108 T7107 arg1Of hours,6
R5301 T7112 T7109 arg2Of insult,after
R5302 T7112 T7110 arg1Of insult,the
R5303 T7112 T7111 arg1Of insult,ICH
R5304 T7114 T7113 arg2Of maintained,and
R5305 T7114 T7115 arg1Of maintained,at
R5306 T7114 T7119 arg1Of maintained,for
R5307 T7118 T7115 arg2Of level,at
R5308 T7118 T7116 arg1Of level,a
R5309 T7118 T7117 arg1Of level,high
R5310 T7121 T7119 arg2Of days,for
R5311 T7121 T7120 arg1Of days,7
R5312 T7121 T7122 arg1Of days,afterward
R5313 T7125 T7123 arg1Of protein,The
R5314 T7125 T7124 arg1Of protein,TLR4
R5315 T7125 T7126 arg1Of protein,","
R5316 T7125 T7127 arg2Of protein,detected
R5317 T7125 T7131 arg1Of protein,was
R5318 T7125 T7133 arg2Of protein,distributed
R5319 T7129 T7127 arg1Of immunohistochemistry,detected
R5320 T7129 T7128 arg2Of immunohistochemistry,by
R5321 T7133 T7130 arg1Of distributed,","
R5322 T7133 T7131 arg2Of distributed,was
R5323 T7133 T7132 arg1Of distributed,consistently
R5324 T7133 T7134 arg1Of distributed,in
R5325 T7136 T7135 arg1Of areas,peri-hemorrhage
R5326 T7136 T7137 arg1Of areas,","
R5327 T7136 T7146 arg1Of areas,and
R5328 T7139 T7138 arg1Of hippocampus,the
R5329 T7139 T7140 arg1Of hippocampus,","
R5330 T7139 T7142 arg1Of hippocampus,","
R5331 T7141 T7140 arg2Of cortex,","
R5332 T7142 T7137 arg2Of ",",","
R5333 T7144 T7142 arg2Of nuclei,","
R5334 T7144 T7143 arg1Of nuclei,thalamic
R5335 T7146 T7134 arg2Of and,in
R5336 T7146 T7145 arg1Of and,","
R5337 T7150 T7146 arg2Of tracts,and
R5338 T7150 T7147 arg1Of tracts,some
R5339 T7150 T7148 arg1Of tracts,white
R5340 T7150 T7149 arg1Of tracts,matter
R5341 T7152 T7151 arg1Of data,These
R5342 T7152 T7153 arg1Of data,indicated
R5343 T7156 T7155 arg2Of expression,increased
R5344 T7156 T7157 arg1Of expression,of
R5345 T7156 T7159 arg1Of expression,may
R5346 T7156 T7160 arg1Of expression,be
R5347 T7156 T7161 arg1Of expression,related
R5348 T7158 T7157 arg2Of TLR4,of
R5349 T7160 T7153 arg2Of be,indicated
R5350 T7160 T7154 arg1Of be,that
R5351 T7160 T7159 arg2Of be,may
R5352 T7161 T7160 arg2Of related,be
R5353 T7161 T7162 arg1Of related,to
R5354 T7164 T7162 arg2Of triggering,to
R5355 T7164 T7163 arg1Of triggering,the
R5356 T7164 T7165 arg1Of triggering,of
R5357 T7168 T7165 arg2Of responses,of
R5358 T7168 T7166 arg1Of responses,the
R5359 T7168 T7167 arg1Of responses,inflammatory
R5360 T7168 T7169 arg1Of responses,in
R5361 T7172 T7169 arg2Of tissue,in
R5362 T7172 T7170 arg1Of tissue,the
R5363 T7172 T7171 arg1Of tissue,brain
R5364 T7172 T7173 arg1Of tissue,after
R5365 T7174 T7173 arg2Of ICH,after
R5366 T7176 T7175 arg1Of studies,Recent
R5367 T7176 T7177 arg1Of studies,demonstrated
R5368 T7179 T7180 arg1Of ICH,initiates
R5369 T7180 T7177 arg2Of initiates,demonstrated
R5370 T7180 T7178 arg1Of initiates,that
R5371 T7182 T7180 arg2Of responses,initiates
R5372 T7182 T7181 arg1Of responses,inflammatory
R5373 T7182 T7183 arg1Of responses,","
R5374 T7182 T7184 arg1Of responses,which
R5375 T7182 T7185 arg1Of responses,are
R5376 T7182 T7186 arg2Of responses,associated
R5377 T7186 T7185 arg2Of associated,are
R5378 T7186 T7187 arg1Of associated,with
R5379 T7189 T7188 arg1Of growth,secondary
R5380 T7189 T7190 arg1Of growth,of
R5381 T7189 T7192 arg1Of growth,and
R5382 T7191 T7190 arg2Of hemorrhage,of
R5383 T7192 T7187 arg2Of and,with
R5384 T7194 T7192 arg2Of death,and
R5385 T7194 T7193 arg1Of death,cell
R5386 T7194 T7195 arg1Of death,[
R5387 T7196 T7195 arg2Of 18,[
R5388 T7197 T7195 arg3Of ],[
R5389 T7198 T7199 arg1Of It,is
R5390 T7198 T7201 arg2Of It,believed
R5391 T7201 T7199 arg2Of believed,is
R5392 T7201 T7200 arg1Of believed,now
R5393 T7204 T7203 arg1Of pathway,TLR4-mediated-NFκB
R5394 T7204 T7205 arg1Of pathway,activates
R5395 T7204 T7207 arg1Of pathway,regulates
R5396 T7205 T7206 arg1Of activates,and
R5397 T7206 T7201 arg3Of and,believed
R5398 T7206 T7202 arg1Of and,that
R5399 T7207 T7206 arg2Of regulates,and
R54 T192 T191 arg2Of NFκB,(
R5400 T7208 T7209 arg1Of immunological,and
R5401 T7210 T7209 arg2Of inflammatory,and
R5402 T7211 T7205 arg2Of responses,activates
R5403 T7211 T7207 arg2Of responses,regulates
R5404 T7211 T7208 arg1Of responses,immunological
R5405 T7211 T7210 arg1Of responses,inflammatory
R5406 T7213 T7212 arg1Of investigate,To
R5407 T7213 T7221 arg1Of investigate,in
R5408 T7215 T7213 arg2Of mechanisms,investigate
R5409 T7215 T7214 arg1Of mechanisms,the
R5410 T7215 T7216 arg1Of mechanisms,underlying
R5411 T7220 T7216 arg2Of responses,underlying
R5412 T7220 T7217 arg1Of responses,the
R5413 T7220 T7218 arg2Of responses,increased
R5414 T7220 T7219 arg1Of responses,inflammatory
R5415 T7223 T7221 arg2Of brain,in
R5416 T7223 T7222 arg1Of brain,the
R5417 T7223 T7224 arg1Of brain,after
R5418 T7225 T7224 arg2Of ICH,after
R5419 T7230 T7227 arg2Of study,in
R5420 T7230 T7228 arg1Of study,the
R5421 T7230 T7229 arg1Of study,present
R5422 T7232 T7213 arg1Of we,investigate
R5423 T7232 T7233 arg1Of we,evaluated
R5424 T7232 T7241 arg1Of we,detecting
R5425 T7233 T7212 modOf evaluated,To
R5426 T7233 T7226 arg1Of evaluated,","
R5427 T7233 T7227 arg1Of evaluated,in
R5428 T7233 T7231 arg1Of evaluated,","
R5429 T7233 T7240 arg1Of evaluated,by
R5430 T7235 T7233 arg2Of activation,evaluated
R5431 T7235 T7234 arg1Of activation,the
R5432 T7235 T7236 arg1Of activation,of
R5433 T7239 T7236 arg2Of signaling,of
R5434 T7239 T7237 arg1Of signaling,TLR4-mediated
R5435 T7239 T7238 arg1Of signaling,NFκB
R5436 T7241 T7240 arg2Of detecting,by
R5437 T7241 T7249 arg1Of detecting,in
R5438 T7243 T7242 arg1Of p-IκB,the
R5439 T7243 T7244 arg1Of p-IκB,and
R5440 T7244 T7241 arg2Of and,detecting
R5441 T7246 T7244 arg2Of activity,and
R5442 T7246 T7245 arg1Of activity,the
R5443 T7246 T7247 arg1Of activity,of
R5444 T7248 T7247 arg2Of NFκB,of
R5445 T7251 T7249 arg2Of brains,in
R5446 T7251 T7250 arg1Of brains,hemorrhagic
R5447 T7252 T7253 arg1Of NFκB,is
R5448 T7253 T7258 arg1Of is,downstream
R5449 T7253 T7259 arg1Of is,in
R5450 T7257 T7253 arg2Of factor,is
R5451 T7257 T7254 arg1Of factor,an
R5452 T7257 T7255 arg1Of factor,important
R5453 T7257 T7256 arg1Of factor,transcription
R5454 T7263 T7259 arg2Of pathway,in
R5455 T7263 T7260 arg1Of pathway,the
R5456 T7263 T7261 arg1Of pathway,TLR4-mediated
R5457 T7263 T7262 arg1Of pathway,signaling
R5458 T7264 T7265 arg1Of Activation,of
R5459 T7264 T7267 arg1Of Activation,stimulates
R5460 T7266 T7265 arg2Of TLR4,of
R5461 T7267 T7272 arg1Of stimulates,","
R5462 T7267 T7273 modOf stimulates,resulting
R5463 T7269 T7270 arg1Of phosphorylation,and
R5464 T7270 T7267 arg2Of and,stimulates
R5465 T7270 T7268 arg1Of and,IκBα
R5466 T7271 T7270 arg2Of degradation,and
R5467 T7273 T7274 arg1Of resulting,in
R5468 T7276 T7274 arg2Of translocation,in
R5469 T7276 T7275 arg1Of translocation,nuclear
R5470 T7276 T7277 arg1Of translocation,of
R5471 T7276 T7279 arg1Of translocation,","
R5472 T7276 T7280 arg1Of translocation,which
R5473 T7276 T7281 arg1Of translocation,initiates
R5474 T7278 T7277 arg2Of NFκB,of
R5475 T7282 T7281 arg2Of transcription,initiates
R5476 T7282 T7283 arg1Of transcription,of
R5477 T7284 T7285 arg2Of genes,associated
R5478 T7284 T7290 arg1Of genes,and
R5479 T7285 T7286 arg1Of associated,with
R5480 T7289 T7286 arg2Of responses,with
R5481 T7289 T7287 arg1Of responses,innate
R5482 T7289 T7288 arg1Of responses,immune
R5483 T7290 T7283 arg2Of and,of
R5484 T7291 T7290 arg2Of inflammation,and
R5485 T7291 T7292 arg1Of inflammation,[
R5486 T7293 T7292 arg2Of 5,[
R5487 T7293 T7294 arg1Of 5,","
R5488 T7295 T7294 arg2Of 6,","
R5489 T7296 T7292 arg3Of ],[
R5490 T7297 T7298 arg1Of We,observed
R5491 T7301 T7300 arg1Of levels,the
R5492 T7301 T7302 arg1Of levels,of
R5493 T7301 T7311 arg1Of levels,were
R5494 T7301 T7313 arg2Of levels,increased
R5495 T7303 T7304 arg1Of phosphorylation,of
R5496 T7303 T7306 arg1Of phosphorylation,and
R5497 T7305 T7304 arg2Of IκB,of
R5498 T7306 T7302 arg2Of and,of
R5499 T7308 T7306 arg2Of activity,and
R55 T193 T191 arg3Of ),(
R5500 T7308 T7307 arg1Of activity,the
R5501 T7308 T7309 arg1Of activity,of
R5502 T7310 T7309 arg2Of NFκB,of
R5503 T7313 T7298 arg2Of increased,observed
R5504 T7313 T7299 arg1Of increased,that
R5505 T7313 T7311 arg2Of increased,were
R5506 T7313 T7312 arg1Of increased,significantly
R5507 T7313 T7314 arg1Of increased,in
R5508 T7316 T7314 arg2Of tissue,in
R5509 T7316 T7315 arg1Of tissue,brain
R5510 T7316 T7317 arg1Of tissue,after
R5511 T7318 T7317 arg2Of ICH,after
R5512 T7321 T7319 arg1Of profile,The
R5513 T7321 T7320 arg1Of profile,temporal
R5514 T7321 T7322 arg1Of profile,of
R5515 T7321 T7327 arg1Of profile,and
R5516 T7324 T7322 arg2Of expression,of
R5517 T7324 T7323 arg1Of expression,the
R5518 T7324 T7325 arg1Of expression,of
R5519 T7326 T7325 arg2Of p-IκB,of
R5520 T7327 T7332 arg1Of and,was
R5521 T7327 T7333 arg1Of and,similar
R5522 T7329 T7327 arg2Of activation,and
R5523 T7329 T7328 arg1Of activation,the
R5524 T7329 T7330 arg1Of activation,of
R5525 T7331 T7330 arg2Of NFκB,of
R5526 T7333 T7332 arg2Of similar,was
R5527 T7333 T7334 arg1Of similar,to
R5528 T7335 T7334 arg2Of that,to
R5529 T7335 T7336 arg1Of that,of
R5530 T7338 T7336 arg2Of expression,of
R5531 T7338 T7337 arg1Of expression,the
R5532 T7338 T7339 arg1Of expression,of
R5533 T7340 T7339 arg2Of TLR4,of
R5534 T7342 T7341 arg1Of data,Our
R5535 T7342 T7343 arg1Of data,suggest
R5536 T7345 T7346 arg1Of ICH,stimulates
R5537 T7346 T7343 arg2Of stimulates,suggest
R5538 T7346 T7344 arg1Of stimulates,that
R5539 T7347 T7346 arg2Of activation,stimulates
R5540 T7347 T7348 arg1Of activation,of
R5541 T7352 T7348 arg2Of pathway,of
R5542 T7352 T7349 arg1Of pathway,the
R5543 T7352 T7350 arg1Of pathway,TLR4/NFκB
R5544 T7352 T7351 arg1Of pathway,signaling
R5545 T7352 T7353 arg1Of pathway,","
R5546 T7352 T7354 arg1Of pathway,which
R5547 T7352 T7355 arg1Of pathway,is
R5548 T7352 T7356 arg1Of pathway,consistent
R5549 T7356 T7355 arg2Of consistent,is
R5550 T7356 T7357 arg1Of consistent,with
R5551 T7359 T7357 arg2Of reports,with
R5552 T7359 T7358 arg1Of reports,previous
R5553 T7361 T7362 arg1Of activation,of
R5554 T7361 T7364 arg1Of activation,is
R5555 T7361 T7365 arg2Of activation,regulated
R5556 T7363 T7362 arg2Of NFκB,of
R5557 T7365 T7359 arg2Of regulated,reports
R5558 T7365 T7360 arg1Of regulated,that
R5559 T7365 T7364 arg2Of regulated,is
R5560 T7365 T7366 arg1Of regulated,through
R5561 T7370 T7366 arg2Of pathway,through
R5562 T7370 T7367 arg1Of pathway,the
R5563 T7370 T7368 arg1Of pathway,TLR4-mediated
R5564 T7370 T7369 arg1Of pathway,signaling
R5565 T7371 T7372 arg1Of TLR4,plays
R5566 T7371 T7388 arg1Of TLR4,can
R5567 T7371 T7390 arg1Of TLR4,recognize
R5568 T7372 T7376 arg1Of plays,in
R5569 T7372 T7382 arg1Of plays,[
R5570 T7372 T7387 arg1Of plays,and
R5571 T7375 T7372 arg2Of role,plays
R5572 T7375 T7373 arg1Of role,an
R5573 T7375 T7374 arg1Of role,important
R5574 T7378 T7376 arg2Of recognition,in
R5575 T7378 T7377 arg1Of recognition,the
R5576 T7378 T7379 arg1Of recognition,of
R5577 T7381 T7379 arg2Of components,of
R5578 T7381 T7380 arg1Of components,microbial
R5579 T7383 T7384 arg1Of 19,","
R5580 T7384 T7382 arg2Of ",",[
R5581 T7385 T7384 arg2Of 20,","
R5582 T7386 T7382 arg3Of ],[
R5583 T7390 T7387 arg2Of recognize,and
R5584 T7390 T7388 arg2Of recognize,can
R5585 T7390 T7389 arg1Of recognize,also
R5586 T7392 T7391 arg1Of molecules,endogenous
R5587 T7392 T7394 arg1Of molecules,as
R5588 T7392 T7405 arg1Of molecules,","
R5589 T7394 T7393 arg1Of as,such
R5590 T7397 T7394 arg2Of products,as
R5591 T7397 T7395 arg1Of products,the
R5592 T7397 T7396 arg1Of products,degradation
R5593 T7397 T7398 arg1Of products,of
R5594 T7397 T7400 arg1Of products,","
R5595 T7399 T7398 arg2Of macromolecules,of
R5596 T7401 T7400 arg2Of products,","
R5597 T7401 T7402 arg1Of products,of
R5598 T7404 T7402 arg2Of cascades,of
R5599 T7404 T7403 arg1Of cascades,proteolytic
R56 T194 T183 arg1Of signaling,4-
R5600 T7405 T7412 arg1Of ",",and
R5601 T7407 T7405 arg2Of components,","
R5602 T7407 T7406 arg1Of components,intracellular
R5603 T7407 T7408 arg1Of components,of
R5604 T7410 T7408 arg2Of cells,of
R5605 T7410 T7409 arg1Of cells,ruptured
R5606 T7412 T7390 arg2Of and,recognize
R5607 T7412 T7411 arg1Of and,","
R5608 T7413 T7412 arg2Of products,and
R5609 T7413 T7414 arg1Of products,of
R5610 T7415 T7414 arg2Of genes,of
R5611 T7415 T7416 arg1Of genes,that
R5612 T7415 T7417 arg1Of genes,are
R5613 T7415 T7418 arg2Of genes,activated
R5614 T7418 T7417 arg2Of activated,are
R5615 T7420 T7418 arg1Of inflammation,activated
R5616 T7420 T7419 arg2Of inflammation,by
R5617 T7422 T7421 arg2Of instance,For
R5618 T7424 T7425 arg1Of HSP70,","
R5619 T7425 T7427 arg1Of ",",","
R562 T932 T931 arg1Of hemorrhage,Intracerebral
R5620 T7426 T7425 arg2Of HSP32,","
R5621 T7427 T7430 arg1Of ",",and
R5622 T7428 T7427 arg2Of HSP27,","
R5623 T7430 T7429 arg1Of and,","
R5624 T7430 T7436 arg1Of and,are
R5625 T7430 T7437 arg2Of and,found
R5626 T7430 T7439 arg1Of and,be
R5627 T7430 T7440 arg2Of and,upregulated
R5628 T7431 T7430 arg2Of enzymes,and
R5629 T7431 T7432 arg2Of enzymes,involved
R563 T932 T933 arg1Of hemorrhage,(
R5630 T7432 T7433 arg1Of involved,in
R5631 T7435 T7433 arg2Of stress,in
R5632 T7435 T7434 arg1Of stress,oxidative
R5633 T7437 T7421 arg1Of found,For
R5634 T7437 T7423 arg1Of found,","
R5635 T7437 T7436 arg2Of found,are
R5636 T7440 T7437 arg3Of upregulated,found
R5637 T7440 T7438 arg1Of upregulated,to
R5638 T7440 T7439 arg2Of upregulated,be
R5639 T7440 T7441 arg1Of upregulated,in
R564 T932 T936 arg1Of hemorrhage,represents
R5640 T7443 T7441 arg2Of brain,in
R5641 T7443 T7442 arg1Of brain,the
R5642 T7443 T7444 arg1Of brain,after
R5643 T7443 T7446 arg1Of brain,","
R5644 T7443 T7447 arg1Of brain,which
R5645 T7443 T7448 arg1Of brain,may
R5646 T7443 T7449 arg1Of brain,be
R5647 T7443 T7450 arg2Of brain,produced
R5648 T7445 T7444 arg2Of ICH,after
R5649 T7450 T7448 arg2Of produced,may
R565 T932 T945 arg1Of hemorrhage,occurs
R5650 T7450 T7449 arg2Of produced,be
R5651 T7454 T7452 arg2Of cells,injured
R5652 T7454 T7453 arg1Of cells,neuronal
R5653 T7454 T7455 arg1Of cells,or
R5654 T7455 T7450 arg1Of or,produced
R5655 T7455 T7451 arg2Of or,by
R5656 T7457 T7455 arg2Of cells,or
R5657 T7457 T7456 arg1Of cells,blood
R5658 T7457 T7458 arg1Of cells,[
R5659 T7459 T7458 arg2Of 21,[
R566 T934 T933 arg2Of ICH,(
R5660 T7460 T7458 arg3Of ],[
R5661 T7467 T7466 arg1Of molecules,these
R5662 T7467 T7468 arg2Of molecules,produced
R5663 T7467 T7473 arg1Of molecules,came
R5664 T7467 T7487 arg1Of molecules,activate
R5665 T7468 T7469 arg1Of produced,in
R5666 T7471 T7469 arg2Of brain,in
R5667 T7471 T7470 arg2Of brain,damaged
R5668 T7471 T7472 arg1Of brain,or
R5669 T7473 T7474 arg1Of came,from
R567 T935 T933 arg3Of ),(
R5670 T7473 T7482 arg1Of came,as
R5671 T7473 T7486 arg1Of came,","
R5672 T7476 T7475 arg1Of cells,blood
R5673 T7476 T7477 arg1Of cells,and
R5674 T7477 T7474 arg2Of and,from
R5675 T7478 T7477 arg2Of constituents,and
R5676 T7478 T7479 arg1Of constituents,of
R5677 T7481 T7479 arg2Of server,of
R5678 T7481 T7480 arg1Of server,plasma
R5679 T7485 T7482 arg2Of ligands,as
R568 T936 T944 arg1Of represents,and
R5680 T7485 T7483 arg1Of ligands,endogenous
R5681 T7485 T7484 arg1Of ligands,TLR4
R5682 T7486 T7464 arg2Of ",",speculated
R5683 T7486 T7465 arg1Of ",",that
R5684 T7487 T7486 arg2Of activate,","
R5685 T7490 T7487 arg2Of signaling,activate
R5686 T7490 T7488 arg1Of signaling,TLR4-mediated
R5687 T7490 T7489 arg1Of signaling,NFκB
R5688 T7492 T7491 arg1Of and,","
R5689 T7493 T7492 arg2Of initiate,and
R569 T940 T936 arg2Of %,represents
R5690 T7496 T7493 arg2Of responses,initiate
R5691 T7496 T7494 arg1Of responses,the
R5692 T7496 T7495 arg1Of responses,inflammatory
R5693 T7496 T7497 arg1Of responses,in
R5694 T7499 T7497 arg2Of brain,in
R5695 T7499 T7498 arg1Of brain,IHC
R5696 T7505 T7502 arg1Of ligands,the
R5697 T7505 T7503 arg1Of ligands,specific
R5698 T7505 T7504 arg1Of ligands,endogenous
R5699 T7505 T7506 arg1Of ligands,for
R57 T194 T187 arg2Of signaling,mediated
R570 T940 T937 arg1Of %,10
R5700 T7505 T7511 arg1Of ligands,have
R5701 T7505 T7513 arg1Of ligands,been
R5702 T7505 T7514 arg2Of ligands,determined
R5703 T7505 T7516 arg1Of ligands,need
R5704 T7505 T7518 arg1Of ligands,be
R5705 T7505 T7519 arg2Of ligands,identified
R5706 T7507 T7506 arg2Of TLR4,for
R5707 T7507 T7508 arg1Of TLR4,in
R5708 T7510 T7508 arg2Of brain,in
R5709 T7510 T7509 arg1Of brain,hemorrhagic
R571 T940 T938 arg1Of %,%
R5710 T7514 T7511 arg2Of determined,have
R5711 T7514 T7512 arg1Of determined,not
R5712 T7514 T7513 arg2Of determined,been
R5713 T7514 T7515 arg1Of determined,and
R5714 T7515 T7500 arg1Of and,However
R5715 T7515 T7501 arg1Of and,","
R5716 T7516 T7515 arg2Of need,and
R5717 T7519 T7516 arg2Of identified,need
R5718 T7519 T7517 arg1Of identified,to
R5719 T7519 T7518 arg2Of identified,be
R572 T940 T939 arg1Of %,–15
R5720 T7519 T7520 arg1Of identified,through
R5721 T7522 T7520 arg2Of research,through
R5722 T7522 T7521 arg1Of research,further
R5723 T7524 T7523 arg2Of conclusion,In
R5724 T7528 T7526 arg1Of study,the
R5725 T7528 T7527 arg1Of study,present
R5726 T7528 T7529 arg1Of study,demonstrated
R5727 T7529 T7523 arg1Of demonstrated,In
R5728 T7529 T7525 arg1Of demonstrated,","
R5729 T7532 T7529 arg2Of profile,demonstrated
R573 T940 T941 arg1Of %,of
R5730 T7532 T7530 arg1Of profile,the
R5731 T7532 T7531 arg1Of profile,temporal
R5732 T7532 T7533 arg1Of profile,of
R5733 T7535 T7533 arg2Of activation,of
R5734 T7535 T7534 arg1Of activation,the
R5735 T7535 T7536 arg1Of activation,of
R5736 T7535 T7540 arg1Of activation,in
R5737 T7535 T7543 arg1Of activation,in
R5738 T7535 T7550 arg1Of activation,","
R5739 T7535 T7551 arg1Of activation,which
R574 T943 T941 arg2Of strokes,of
R5740 T7535 T7552 arg1Of activation,suggests
R5741 T7539 T7536 arg2Of signaling,of
R5742 T7539 T7537 arg1Of signaling,TLR4-mediated
R5743 T7539 T7538 arg1Of signaling,NFκB
R5744 T7542 T7540 arg2Of tissue,in
R5745 T7542 T7541 arg1Of tissue,brain
R5746 T7546 T7543 arg2Of model,in
R5747 T7546 T7544 arg1Of model,a
R5748 T7546 T7545 arg1Of model,rat
R5749 T7546 T7547 arg1Of model,of
R575 T943 T942 arg1Of strokes,all
R5750 T7549 T7547 arg2Of ICH,of
R5751 T7549 T7548 arg1Of ICH,experimental
R5752 T7556 T7554 arg1Of signaling,TLR4-mediated
R5753 T7556 T7555 arg1Of signaling,NFκB
R5754 T7556 T7557 arg1Of signaling,participates
R5755 T7557 T7552 arg2Of participates,suggests
R5756 T7557 T7553 arg1Of participates,that
R5757 T7557 T7558 arg1Of participates,in
R5758 T7560 T7558 arg2Of pathogenesis,in
R5759 T7560 T7559 arg1Of pathogenesis,the
R576 T945 T944 arg2Of occurs,and
R5760 T7560 T7561 arg1Of pathogenesis,of
R5761 T7560 T7563 arg1Of pathogenesis,","
R5762 T7560 T7564 arg1Of pathogenesis,which
R5763 T7560 T7565 arg1Of pathogenesis,may
R5764 T7560 T7566 arg1Of pathogenesis,be
R5765 T7562 T7561 arg2Of ICH,of
R5766 T7566 T7565 arg2Of be,may
R5767 T7569 T7566 arg2Of target,be
R5768 T7569 T7567 arg1Of target,a
R5769 T7569 T7568 arg1Of target,therapeutic
R577 T945 T946 arg1Of occurs,with
R5770 T7569 T7570 arg1Of target,for
R5771 T7572 T7570 arg2Of prevention,for
R5772 T7572 T7571 arg1Of prevention,the
R5773 T7572 T7573 arg1Of prevention,of
R5774 T7576 T7573 arg2Of damage,of
R5775 T7576 T7574 arg1Of damage,ICH-induced
R5776 T7576 T7575 arg1Of damage,brain
R578 T945 T949 arg1Of occurs,as
R579 T948 T946 arg2Of frequency,with
R58 T194 T188 arg1Of signaling,nuclear
R580 T948 T947 arg1Of frequency,increasing
R581 T951 T949 arg2Of complication,as
R582 T951 T950 arg1Of complication,a
R583 T951 T952 arg1Of complication,of
R584 T955 T952 arg2Of treatment,of
R585 T955 T953 arg1Of treatment,the
R586 T955 T954 arg1Of treatment,thrombolytic
R587 T955 T956 arg1Of treatment,of
R588 T955 T959 arg1Of treatment,","
R589 T955 T960 arg1Of treatment,which
R59 T194 T189 arg1Of signaling,factor
R590 T955 T961 arg1Of treatment,is
R591 T955 T962 arg2Of treatment,associated
R592 T958 T956 arg2Of stroke,of
R593 T958 T957 arg1Of stroke,ischemic
R594 T962 T961 arg2Of associated,is
R595 T962 T963 arg1Of associated,with
R596 T965 T964 arg1Of mortality,high
R597 T965 T966 arg1Of mortality,and
R598 T966 T963 arg2Of and,with
R599 T966 T969 arg1Of and,in
R60 T194 T190 arg1Of signaling,kappa-B
R600 T968 T966 arg2Of disability,and
R601 T968 T967 arg1Of disability,severe
R602 T970 T969 arg2Of survivors,in
R603 T970 T971 arg1Of survivors,[
R604 T972 T971 arg2Of 1,[
R605 T972 T973 arg1Of 1,","
R606 T974 T973 arg2Of 2,","
R607 T975 T971 arg3Of ],[
R608 T979 T976 arg1Of deformation,Local
R609 T979 T977 arg1Of deformation,brain
R61 T194 T191 arg1Of signaling,(
R610 T979 T978 arg1Of deformation,tissue
R611 T979 T980 arg1Of deformation,induces
R612 T980 T986 arg1Of induces,;
R613 T980 T988 arg1Of induces,importantly
R614 T980 T989 arg1Of induces,","
R615 T983 T980 arg2Of damage,induces
R616 T983 T981 arg1Of damage,primary
R617 T983 T982 arg1Of damage,brain
R618 T983 T984 arg1Of damage,after
R619 T985 T984 arg2Of ICH,after
R62 T194 T195 arg1Of signaling,plays
R620 T988 T987 arg1Of importantly,more
R621 T991 T992 arg1Of excitotoxicity,and
R622 T993 T992 arg2Of inflammatory,and
R623 T994 T989 arg2Of responses,","
R624 T994 T990 arg1Of responses,the
R625 T994 T991 arg1Of responses,excitotoxicity
R626 T994 T993 arg1Of responses,inflammatory
R627 T994 T995 arg1Of responses,in
R628 T998 T995 arg2Of tissue,in
R629 T998 T996 arg1Of tissue,the
R63 T195 T198 arg1Of plays,in
R630 T998 T997 arg1Of tissue,brain
R631 T998 T999 arg2Of tissue,induced
R632 T1002 T999 arg1Of result,induced
R633 T1002 T1000 arg2Of result,by
R634 T1002 T1001 arg1Of result,ICH
R635 T1002 T1003 arg1Of result,in
R636 T1002 T1007 arg1Of result,following
R637 T1006 T1003 arg2Of damage,in
R638 T1006 T1004 arg1Of damage,further
R639 T1006 T1005 arg1Of damage,brain
R64 T197 T195 arg2Of roles,plays
R640 T1008 T1007 arg2Of ICH,following
R641 T1008 T1009 arg1Of ICH,[
R642 T1010 T1009 arg2Of 3,[
R643 T1011 T1009 arg3Of ],[
R644 T1013 T1014 arg1Of innate,and
R645 T1015 T1014 arg2Of adaptive,and
R646 T1017 T1012 arg1Of mechanisms,Both
R647 T1017 T1013 arg1Of mechanisms,innate
R648 T1017 T1015 arg1Of mechanisms,adaptive
R649 T1017 T1016 arg1Of mechanisms,immunological/inflammatory
R65 T197 T196 arg1Of roles,critical
R650 T1017 T1018 arg1Of mechanisms,have
R651 T1017 T1019 arg1Of mechanisms,been
R652 T1017 T1021 arg2Of mechanisms,shown
R653 T1017 T1023 arg1Of mechanisms,participate
R654 T1021 T1018 arg2Of shown,have
R655 T1021 T1019 arg2Of shown,been
R656 T1021 T1020 arg1Of shown,clearly
R657 T1023 T1021 arg3Of participate,shown
R658 T1023 T1022 arg1Of participate,to
R659 T1023 T1024 arg1Of participate,in
R66 T200 T201 arg1Of activation,and
R660 T1026 T1024 arg2Of progression,in
R661 T1026 T1025 arg1Of progression,the
R662 T1026 T1027 arg1Of progression,of
R663 T1026 T1030 arg1Of progression,after
R664 T1029 T1027 arg2Of injury,of
R665 T1029 T1028 arg1Of injury,brain
R666 T1032 T1030 arg2Of stroke,after
R667 T1032 T1031 arg1Of stroke,ischemic
R668 T1035 T1045 arg1Of how,remains
R669 T1035 T1047 arg1Of how,be
R67 T201 T198 arg2Of and,in
R670 T1035 T1048 arg2Of how,elucidated
R671 T1038 T1036 arg1Of responses,the
R672 T1038 T1037 arg1Of responses,inflammatory
R673 T1038 T1039 arg1Of responses,in
R674 T1038 T1041 arg1Of responses,are
R675 T1038 T1042 arg2Of responses,triggered
R676 T1038 T1044 arg2Of responses,regulated
R677 T1040 T1039 arg2Of ICH,in
R678 T1042 T1043 arg1Of triggered,and
R679 T1043 T1035 arg1Of and,how
R68 T201 T199 arg1Of and,the
R680 T1043 T1041 arg2Of and,are
R681 T1044 T1043 arg2Of regulated,and
R682 T1045 T1033 arg1Of remains,Nevertheless
R683 T1045 T1034 arg1Of remains,","
R684 T1048 T1045 arg2Of elucidated,remains
R685 T1048 T1046 arg1Of elucidated,to
R686 T1048 T1047 arg2Of elucidated,be
R687 T1049 T1050 arg1Of TLRs,are
R688 T1049 T1057 arg1Of TLRs,act
R689 T1050 T1056 arg1Of are,and
R69 T201 T203 arg1Of and,of
R690 T1052 T1050 arg2Of family,are
R691 T1052 T1051 arg1Of family,a
R692 T1052 T1053 arg1Of family,of
R693 T1055 T1053 arg2Of proteins,of
R694 T1055 T1054 arg1Of proteins,transmembrane
R695 T1057 T1056 arg2Of act,and
R696 T1057 T1058 arg1Of act,as
R697 T1057 T1062 arg1Of act,[
R698 T1061 T1058 arg2Of molecules,as
R699 T1061 T1059 arg1Of molecules,signal
R70 T201 T206 arg1Of and,in
R700 T1061 T1060 arg1Of molecules,transduction
R701 T1063 T1062 arg2Of 4,[
R702 T1064 T1062 arg3Of ],[
R703 T1065 T1066 arg1Of Activation,of
R704 T1065 T1068 arg1Of Activation,recruits
R705 T1065 T1073 arg1Of Activation,results
R706 T1067 T1066 arg2Of TLRs,of
R707 T1068 T1072 arg1Of recruits,and
R708 T1071 T1068 arg2Of proteins,recruits
R709 T1071 T1069 arg1Of proteins,downstream
R71 T202 T201 arg2Of regulation,and
R710 T1071 T1070 arg1Of proteins,signaling
R711 T1073 T1072 arg2Of results,and
R712 T1073 T1074 arg1Of results,in
R713 T1075 T1074 arg2Of transcription,in
R714 T1075 T1076 arg1Of transcription,of
R715 T1077 T1076 arg2Of genes,of
R716 T1077 T1078 arg1Of genes,encoding
R717 T1080 T1081 arg1Of molecules,and
R718 T1081 T1078 arg2Of and,encoding
R719 T1081 T1079 arg1Of and,inflammation-associated
R72 T205 T203 arg2Of responses,of
R720 T1081 T1083 arg1Of and,[
R721 T1082 T1081 arg2Of cytokines,and
R722 T1084 T1083 arg2Of 5,[
R723 T1084 T1085 arg1Of 5,","
R724 T1086 T1085 arg2Of 6,","
R725 T1087 T1083 arg3Of ],[
R726 T1089 T1088 arg2Of example,For
R727 T1091 T1092 arg1Of combined,with
R728 T1094 T1092 arg2Of ligand,with
R729 T1094 T1093 arg1Of ligand,specific
R73 T205 T204 arg1Of responses,inflammatory
R730 T1097 T1091 arg2Of activation,combined
R731 T1097 T1096 arg1Of activation,the
R732 T1097 T1098 arg1Of activation,of
R733 T1097 T1100 arg1Of activation,induces
R734 T1097 T1111 arg1Of activation,dissociates
R735 T1099 T1098 arg2Of TLR4,of
R736 T1100 T1110 arg1Of induces,and
R737 T1102 T1100 arg2Of phosphorylation,induces
R738 T1102 T1101 arg1Of phosphorylation,the
R739 T1102 T1103 arg1Of phosphorylation,of
R74 T208 T206 arg2Of brain,in
R740 T1104 T1103 arg2Of inhibitor,of
R741 T1104 T1105 arg1Of inhibitor,of
R742 T1106 T1105 arg2Of kappa-B,of
R743 T1106 T1107 arg1Of kappa-B,(
R744 T1108 T1107 arg2Of IκB,(
R745 T1109 T1107 arg3Of ),(
R746 T1110 T1088 arg1Of and,For
R747 T1110 T1090 arg1Of and,","
R748 T1110 T1091 modOf and,combined
R749 T1110 T1095 arg1Of and,","
R75 T208 T207 arg1Of brain,injured
R750 T1111 T1110 arg2Of dissociates,and
R751 T1112 T1111 arg2Of IκB,dissociates
R752 T1112 T1113 arg1Of IκB,from
R753 T1114 T1113 arg2Of NF-kappa-B,from
R754 T1114 T1115 arg1Of NF-kappa-B,(
R755 T1116 T1115 arg2Of NFκB,(
R756 T1117 T1115 arg3Of ),(
R757 T1120 T1121 arg1Of NFκB,trans-locates
R758 T1120 T1126 arg1Of NFκB,activates
R759 T1120 T1128 arg1Of NFκB,regulates
R76 T212 T211 arg1Of involvement,the
R760 T1121 T1122 arg1Of trans-locates,into
R761 T1121 T1125 arg1Of trans-locates,and
R762 T1124 T1122 arg2Of nucleus,into
R763 T1124 T1123 arg1Of nucleus,the
R764 T1125 T1118 arg1Of and,Then
R765 T1125 T1119 arg1Of and,","
R766 T1126 T1127 arg1Of activates,and
R767 T1127 T1125 arg2Of and,and
R768 T1128 T1127 arg2Of regulates,and
R769 T1130 T1126 arg2Of transcription,activates
R77 T212 T213 arg1Of involvement,of
R770 T1130 T1128 arg2Of transcription,regulates
R771 T1130 T1129 arg1Of transcription,the
R772 T1130 T1131 arg1Of transcription,of
R773 T1132 T1131 arg2Of genes,of
R774 T1132 T1133 arg2Of genes,related
R775 T1133 T1134 arg1Of related,to
R776 T1133 T1137 arg1Of related,[
R777 T1136 T1134 arg2Of responses,to
R778 T1136 T1135 arg1Of responses,inflammatory
R779 T1138 T1137 arg2Of 5,[
R78 T212 T217 arg1Of involvement,in
R780 T1138 T1139 arg1Of 5,","
R781 T1140 T1139 arg2Of 6,","
R782 T1141 T1137 arg3Of ],[
R783 T1142 T1143 arg1Of TLRs,play
R784 T1142 T1154 arg1Of TLRs,are
R785 T1142 T1155 arg2Of TLRs,implicated
R786 T1143 T1147 arg1Of play,in
R787 T1143 T1153 arg1Of play,and
R788 T1146 T1143 arg2Of role,play
R789 T1146 T1144 arg1Of role,a
R79 T212 T222 arg1Of involvement,remains
R790 T1146 T1145 arg1Of role,critical
R791 T1149 T1147 arg2Of induction,in
R792 T1149 T1148 arg1Of induction,the
R793 T1149 T1150 arg1Of induction,of
R794 T1152 T1150 arg2Of responses,of
R795 T1152 T1151 arg1Of responses,immunological/inflammatory
R796 T1155 T1153 arg2Of implicated,and
R797 T1155 T1154 arg2Of implicated,are
R798 T1155 T1156 arg1Of implicated,in
R799 T1159 T1156 arg2Of diseases,in
R80 T212 T223 arg1Of involvement,unknown
R800 T1159 T1157 arg1Of diseases,several
R801 T1159 T1158 arg1Of diseases,CNS
R802 T1159 T1160 arg1Of diseases,","
R803 T1159 T1162 arg1Of diseases,as
R804 T1162 T1161 arg1Of as,such
R805 T1164 T1163 arg1Of disease,infectious
R806 T1164 T1165 arg1Of disease,","
R807 T1165 T1169 arg1Of ",",and
R808 T1167 T1165 arg2Of disease,","
R809 T1167 T1166 arg1Of disease,autoimmune
R81 T216 T213 arg2Of signaling,of
R810 T1169 T1162 arg2Of and,as
R811 T1169 T1168 arg1Of and,","
R812 T1172 T1169 arg2Of injury,and
R813 T1172 T1170 arg1Of injury,ischemic
R814 T1172 T1171 arg1Of injury,brain
R815 T1172 T1173 arg1Of injury,[
R816 T1174 T1173 arg2Of 7,[
R817 T1174 T1175 arg1Of 7,","
R818 T1176 T1175 arg2Of 8,","
R819 T1177 T1173 arg3Of ],[
R82 T216 T214 arg1Of signaling,TLR4-mediated
R820 T1179 T1178 arg1Of evidences,Accumulating
R821 T1179 T1180 arg1Of evidences,demonstrate
R822 T1182 T1183 arg1Of TLR4,","
R823 T1182 T1190 arg1Of TLR4,contributes
R824 T1187 T1183 arg2Of TLR,","
R825 T1187 T1184 arg1Of TLR,the
R826 T1187 T1185 arg1Of TLR,first
R827 T1187 T1186 arg1Of TLR,mammalian
R828 T1187 T1188 arg2Of TLR,recognized
R829 T1190 T1180 arg2Of contributes,demonstrate
R83 T216 T215 arg1Of signaling,NFκB
R830 T1190 T1181 arg1Of contributes,that
R831 T1190 T1189 arg1Of contributes,","
R832 T1190 T1191 arg1Of contributes,to
R833 T1194 T1192 arg1Of death,the
R834 T1194 T1193 arg1Of death,neuronal
R835 T1194 T1195 arg1Of death,","
R836 T1194 T1200 arg1Of death,","
R837 T1194 T1204 arg1Of death,and
R838 T1199 T1195 arg2Of damage,","
R839 T1199 T1196 arg1Of damage,blood
R84 T219 T217 arg2Of pathogenesis,in
R840 T1199 T1197 arg1Of damage,brain
R841 T1199 T1198 arg1Of damage,barrier
R842 T1202 T1200 arg2Of edema,","
R843 T1202 T1201 arg1Of edema,brain
R844 T1204 T1191 arg2Of and,to
R845 T1204 T1203 arg1Of and,","
R846 T1206 T1204 arg2Of responses,and
R847 T1206 T1205 arg1Of responses,inflammatory
R848 T1206 T1207 arg1Of responses,in
R849 T1210 T1207 arg2Of injury,in
R85 T219 T218 arg1Of pathogenesis,the
R850 T1210 T1208 arg1Of injury,the
R851 T1210 T1209 arg1Of injury,brain
R852 T1210 T1211 arg2Of injury,induced
R853 T1211 T1214 arg1Of induced,[
R854 T1213 T1211 arg1Of ischemia,induced
R855 T1213 T1212 arg2Of ischemia,by
R856 T1215 T1214 arg2Of 8,[
R857 T1215 T1216 arg1Of 8,","
R858 T1217 T1216 arg2Of 9,","
R859 T1218 T1214 arg3Of ],[
R86 T219 T220 arg1Of pathogenesis,of
R860 T1221 T1222 arg1Of little,is
R861 T1221 T1223 arg2Of little,known
R862 T1223 T1219 arg1Of known,However
R863 T1223 T1220 arg1Of known,","
R864 T1223 T1222 arg2Of known,is
R865 T1223 T1224 arg1Of known,about
R866 T1225 T1224 arg2Of TLR4,about
R867 T1225 T1226 arg1Of TLR4,in
R868 T1228 T1226 arg2Of brain,in
R869 T1228 T1227 arg1Of brain,the
R87 T221 T220 arg2Of ICH,of
R870 T1228 T1229 arg1Of brain,after
R871 T1230 T1229 arg2Of ICH,after
R872 T1234 T1231 arg2Of study,In
R873 T1234 T1232 arg1Of study,the
R874 T1234 T1233 arg1Of study,present
R875 T1236 T1237 arg1Of we,detected
R876 T1237 T1231 arg1Of detected,In
R877 T1237 T1235 arg1Of detected,","
R878 T1239 T1238 arg1Of transcription,the
R879 T1239 T1240 arg1Of transcription,of
R88 T222 T209 arg1Of remains,However
R880 T1239 T1243 arg1Of transcription,and
R881 T1242 T1240 arg2Of gene,of
R882 T1242 T1241 arg1Of gene,TLR4
R883 T1243 T1237 arg2Of and,detected
R884 T1245 T1243 arg2Of activation,and
R885 T1245 T1244 arg1Of activation,the
R886 T1245 T1246 arg1Of activation,of
R887 T1245 T1249 arg1Of activation,in
R888 T1248 T1246 arg2Of signaling,of
R889 T1248 T1247 arg1Of signaling,TLR4-mediated
R89 T222 T210 arg1Of remains,","
R890 T1252 T1249 arg2Of brains,in
R891 T1252 T1250 arg1Of brains,the
R892 T1252 T1251 arg1Of brains,rat
R893 T1252 T1253 arg2Of brains,subjected
R894 T1253 T1254 arg1Of subjected,to
R895 T1256 T1254 arg2Of ICH,to
R896 T1256 T1255 arg1Of ICH,experimental
R897 T1258 T1257 arg1Of data,Our
R898 T1258 T1260 arg1Of data,provided
R899 T1260 T1259 arg1Of provided,firstly
R90 T223 T222 arg2Of unknown,remains
R900 T1262 T1261 arg1Of knowledge,the
R901 T1262 T1263 arg1Of knowledge,about
R902 T1262 T1268 arg1Of knowledge,and
R903 T1265 T1263 arg2Of distribution,about
R904 T1265 T1264 arg1Of distribution,the
R905 T1265 T1266 arg1Of distribution,of
R906 T1267 T1266 arg2Of TLR4,of
R907 T1268 T1260 arg2Of and,provided
R908 T1271 T1268 arg2Of profile,and
R909 T1271 T1269 arg1Of profile,the
R91 T226 T224 arg1Of study,The
R910 T1271 T1270 arg1Of profile,temporal
R911 T1271 T1272 arg1Of profile,of
R912 T1274 T1272 arg2Of activation,of
R913 T1274 T1273 arg1Of activation,the
R914 T1274 T1275 arg1Of activation,of
R915 T1274 T1278 arg1Of activation,in
R916 T1277 T1275 arg2Of signaling,of
R917 T1277 T1276 arg1Of signaling,TLR4-mediated
R918 T1281 T1278 arg2Of tissue,in
R919 T1281 T1279 arg1Of tissue,rat
R92 T226 T225 arg1Of study,present
R920 T1281 T1280 arg1Of tissue,brain
R921 T1281 T1282 arg1Of tissue,after
R922 T1283 T1282 arg2Of ICH,after
R93 T226 T227 arg1Of study,was
R94 T229 T227 arg2Of evaluate,was
R95 T229 T228 arg1Of evaluate,to
R96 T232 T230 arg1Of profile,the
R97 T232 T231 arg1Of profile,temporal
R98 T232 T233 arg1Of profile,of
R99 T232 T238 arg1Of profile,and