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Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T154 0-14 NN denotes Interleukin-10
T155 15-25 NN denotes Production
T156 26-28 IN denotes by
T157 29-32 NN denotes Th1
T158 33-38 NN denotes Cells
T159 39-47 VB denotes Requires
T160 48-70 JJ denotes Interleukin-12-Induced
T161 71-76 NN denotes STAT4
T162 77-90 NN denotes Transcription
T163 91-97 NN denotes Factor
T164 98-101 CC denotes and
T165 102-105 NN denotes ERK
T166 106-109 NN denotes MAP
T167 110-116 NN denotes Kinase
T168 117-127 NN denotes Activation
T169 128-130 IN denotes by
T170 131-135 JJ denotes High
T171 136-143 NN denotes Antigen
T172 144-148 NN denotes Dose
T173 160-167 NNP denotes Summary
T174 168-172 JJ denotes CD4+
T175 173-180 NN denotes T cells
T176 181-190 VB denotes producing
T177 191-205 NN denotes interleukin-10
T178 206-207 -LRB- denotes (
T179 207-212 NN denotes IL-10
T180 212-213 -RRB- denotes )
T181 214-217 CC denotes and
T182 218-230 NN denotes interferon-γ
T183 231-232 -LRB- denotes (
T184 232-237 NN denotes IFN-γ
T185 237-238 -RRB- denotes )
T186 239-242 VB denotes are
T187 243-251 VB denotes reported
T188 252-254 IN denotes in
T189 255-262 JJ denotes chronic
T190 263-273 NN denotes infections
T191 275-282 RB denotes However
T192 282-283 -COMMA- denotes ,
T193 284-287 DT denotes the
T194 288-295 NN denotes signals
T195 296-300 WDT denotes that
T196 301-307 VB denotes direct
T197 308-311 DT denotes the
T198 312-323 NN denotes development
T199 324-326 IN denotes of
T200 327-342 JJ denotes IL-10-producing
T201 343-344 NN denotes T
T202 345-351 NN denotes helper
T203 352-353 CD denotes 1
T204 354-355 -LRB- denotes (
T205 355-358 NN denotes Th1
T206 358-359 -RRB- denotes )
T207 360-365 NN denotes cells
T208 366-369 VB denotes are
T209 370-379 JJ denotes undefined
T210 381-383 PRP denotes We
T211 384-390 VB denotes showed
T212 391-395 IN denotes that
T213 396-407 NN denotes development
T214 408-410 IN denotes of
T215 411-426 JJ denotes IL-10-producing
T216 427-430 NN denotes Th1
T217 431-436 NN denotes cells
T218 437-445 VB denotes required
T219 446-450 JJ denotes high
T220 451-457 NN denotes T cell
T221 458-466 NN denotes receptor
T222 467-468 -LRB- denotes (
T223 468-471 NN denotes TCR
T224 471-472 -RRB- denotes )
T225 473-481 NN denotes ligation
T226 481-482 -COMMA- denotes ,
T227 483-492 JJ denotes sustained
T228 493-497 NN denotes ERK1
T229 498-501 CC denotes and
T230 502-506 NN denotes ERK2
T231 507-510 NN denotes MAP
T232 511-518 NN denotes kinases
T233 519-534 NN denotes phosphorylation
T234 534-535 -COMMA- denotes ,
T235 536-539 CC denotes and
T236 540-553 JJ denotes IL-12-induced
T237 554-559 NN denotes STAT4
T238 560-573 NN denotes transcription
T239 574-580 NN denotes factor
T240 581-591 NN denotes activation
T241 593-601 VB denotes Repeated
T242 602-605 NN denotes TCR
T243 606-616 NN denotes triggering
T244 617-620 VB denotes led
T245 621-623 TO denotes to
T246 624-632 VB denotes enhanced
T247 633-638 NN denotes IL-10
T248 639-649 NN denotes production
T249 650-652 IN denotes by
T250 653-656 NN denotes Th1
T251 657-662 NN denotes cells
T252 662-663 -COMMA- denotes ,
T253 664-667 CC denotes and
T254 668-677 JJ denotes continued
T255 678-683 NN denotes IL-12
T256 684-690 NN denotes action
T257 691-694 CC denotes and
T258 695-704 JJ denotes high-dose
T259 705-708 NN denotes TCR
T260 709-718 NN denotes signaling
T261 719-723 VB denotes were
T262 724-732 VB denotes required
T263 733-736 IN denotes for
T264 737-740 DT denotes the
T265 741-752 NN denotes development
T266 753-756 CC denotes and
T267 757-768 NN denotes maintenance
T268 769-771 IN denotes of
T269 772-787 JJ denotes IL-10-producing
T270 788-791 NN denotes Th1
T271 792-797 NN denotes cells
T272 799-807 IN denotes Although
T273 808-811 NN denotes Th1
T274 811-812 -COMMA- denotes ,
T275 813-816 NN denotes Th2
T276 816-817 -COMMA- denotes ,
T277 818-821 CC denotes and
T278 822-826 NN denotes Th17
T279 827-832 NN denotes cells
T280 833-840 VB denotes require
T281 841-844 DT denotes the
T282 845-855 NN denotes activation
T283 856-858 IN denotes of
T284 859-867 JJ denotes distinct
T285 868-873 NN denotes STATs
T286 874-877 IN denotes for
T287 878-883 PRP-DOLLAR- denotes their
T288 884-899 NN denotes differentiation
T289 899-900 -COMMA- denotes ,
T290 901-911 NN denotes activation
T291 912-914 IN denotes of
T292 915-919 NN denotes ERK1
T293 920-923 CC denotes and
T294 924-928 NN denotes ERK2
T295 929-934 NN denotes was a
T296 935-941 JJ denotes common
T297 942-953 NN denotes requirement
T298 954-957 IN denotes for
T299 958-968 NN denotes production
T300 969-971 IN denotes of
T301 972-977 NN denotes IL-10
T302 978-980 IN denotes by
T303 981-984 DT denotes all
T304 985-987 NN denotes Th
T305 988-992 NN denotes cell
T306 993-1000 NN denotes subsets
T307 1002-1007 NN denotes IL-10
T308 1008-1018 NN denotes expression
T309 1019-1023 RB denotes also
T310 1024-1034 VB denotes correlated
T311 1035-1039 IN denotes with
T312 1040-1045 NN denotes c-maf
T313 1046-1056 NN denotes expression
T314 1058-1065 IN denotes Despite
T315 1066-1072 VB denotes having
T316 1073-1081 JJ denotes distinct
T317 1082-1091 NN denotes functions
T318 1092-1094 IN denotes in
T319 1095-1105 NN denotes protection
T320 1106-1113 IN denotes against
T321 1114-1123 NN denotes pathogens
T322 1123-1124 -COMMA- denotes ,
T323 1125-1128 DT denotes all
T324 1129-1131 NN denotes Th
T325 1132-1137 NN denotes cells
T326 1138-1143 VB denotes share
T327 1144-1147 DT denotes the
T328 1148-1157 JJ denotes important
T329 1158-1162 NN denotes task
T330 1163-1165 IN denotes of
T331 1166-1177 VB denotes controlling
T332 1178-1191 JJ denotes overexuberant
T333 1192-1198 JJ denotes immune
T334 1199-1208 NN denotes responses
T335 1209-1211 IN denotes by
T336 1212-1217 NN denotes means
T337 1218-1220 IN denotes of
T338 1221-1226 NN denotes IL-10
T339 1227-1237 NN denotes production
T2978 5900-5905 NN denotes IL-12
T2979 5906-5909 CC denotes and
T2980 5910-5914 JJ denotes High
T2981 5915-5920 NN denotes Doses
T2982 5921-5923 IN denotes of
T2983 5924-5931 NN denotes Antigen
T2984 5932-5938 VB denotes Induce
T2985 5939-5942 DT denotes the
T2986 5943-5954 NN denotes Development
T2987 5955-5957 IN denotes of
T2988 5958-5961 NN denotes Th1
T2989 5962-5967 NN denotes Cells
T2990 5968-5977 VB denotes Producing
T2991 5978-5983 NN denotes IL-10
T2992 5984-5986 TO denotes To
T2993 5987-5992 VB denotes study
T2994 5993-5996 DT denotes the
T2995 5997-6012 NN denotes differentiation
T2996 6013-6015 IN denotes of
T2997 6016-6019 NN denotes Th1
T2998 6020-6025 NN denotes cells
T2999 6026-6037 VB denotes coproducing
T3000 6038-6043 NN denotes IFN-γ
T3001 6044-6047 CC denotes and
T3002 6048-6053 NN denotes IL-10
T3003 6053-6054 -COMMA- denotes ,
T3004 6055-6057 PRP denotes we
T3005 6058-6066 VB denotes cultured
T3006 6067-6075 VB denotes purified
T3007 6076-6090 JJ denotes TCR-transgenic
T3008 6091-6098 NN denotes DO11.10
T3009 6099-6104 JJ denotes naive
T3010 6105-6109 JJ denotes CD4+
T3011 6110-6117 NN denotes T cells
T3012 6118-6122 IN denotes with
T3013 6123-6131 VB denotes purified
T3014 6132-6135 NN denotes DCs
T3015 6136-6138 IN denotes as
T3016 6139-6143 NN denotes APCs
T3017 6144-6147 CC denotes and
T3018 6148-6158 VB denotes increasing
T3019 6159-6164 NN denotes doses
T3020 6165-6167 IN denotes of
T3021 6168-6177 NN denotes ovalbumin
T3022 6178-6185 NN denotes peptide
T3023 6186-6193 CD denotes 323-339
T3024 6194-6195 -LRB- denotes (
T3025 6195-6198 NN denotes OVA
T3026 6198-6199 -RRB- denotes )
T3027 6201-6208 NN denotes Culture
T3028 6209-6213 IN denotes with
T3029 6214-6218 JJ denotes high
T3030 6219-6224 NN denotes doses
T3031 6225-6227 IN denotes of
T3032 6228-6235 NN denotes antigen
T3033 6236-6239 IN denotes for
T3034 6240-6241 CD denotes 7
T3035 6242-6246 NN denotes days
T3036 6247-6251 VB denotes gave
T3037 6252-6256 NN denotes rise
T3038 6257-6259 TO denotes to
T3039 6260-6263 NN denotes Th1
T3040 6264-6269 NN denotes cells
T3041 6270-6280 VB denotes expressing
T3042 6281-6286 NN denotes IFN-γ
T3043 6287-6291 IN denotes upon
T3044 6292-6305 NN denotes restimulation
T3045 6306-6307 -LRB- denotes (
T3046 6307-6315 JJ denotes Constant
T3047 6316-6322 NN denotes et al.
T3048 6322-6323 -COMMA- denotes ,
T3049 6324-6328 CD denotes 1995
T3050 6328-6329 -COLON- denotes ;
T3051 6330-6336 NNP denotes Hosken
T3052 6337-6343 FW denotes et al.
T3053 6343-6344 -COMMA- denotes ,
T3054 6345-6349 CD denotes 1995
T3055 6349-6350 -RRB- denotes )
T3056 6350-6351 -COMMA- denotes ,
T3057 6352-6355 CC denotes but
T3058 6356-6359 RB denotes not
T3059 6360-6365 NN denotes IL-10
T3060 6366-6367 -LRB- denotes (
T3061 6367-6377 NN denotes Figure S1A
T3062 6378-6387 JJ denotes available
T3063 6388-6394 NN denotes online
T3064 6394-6395 -RRB- denotes )
T3065 6397-6404 NN denotes Culture
T3066 6405-6409 IN denotes with
T3067 6410-6413 JJ denotes low
T3068 6414-6421 NN denotes antigen
T3069 6422-6427 NN denotes doses
T3070 6428-6433 IN denotes under
T3071 6434-6437 DT denotes the
T3072 6438-6442 JJ denotes same
T3073 6443-6453 NN denotes conditions
T3074 6454-6457 VB denotes led
T3075 6458-6460 TO denotes to
T3076 6461-6464 DT denotes the
T3077 6465-6480 NN denotes differentiation
T3078 6481-6483 IN denotes of
T3079 6484-6487 NN denotes Th2
T3080 6488-6493 NN denotes cells
T3081 6493-6494 -COMMA- denotes ,
T3082 6495-6500 WDT denotes which
T3083 6501-6510 VB denotes expressed
T3084 6511-6515 CC denotes both
T3085 6516-6520 NN denotes IL-4
T3086 6521-6524 CC denotes and
T3087 6525-6530 NN denotes IL-10
T3088 6531-6535 IN denotes upon
T3089 6536-6549 NN denotes restimulation
T3090 6550-6551 -LRB- denotes (
T3091 6551-6561 NN denotes Figure S1A
T3092 6561-6562 -RRB- denotes )
T3093 6564-6571 NN denotes Culture
T3094 6572-6574 IN denotes of
T3095 6575-6580 JJ denotes naive
T3096 6581-6585 JJ denotes CD4+
T3097 6586-6593 NN denotes T cells
T3098 6594-6596 IN denotes in
T3099 6597-6599 DT denotes an
T3100 6600-6608 JJ denotes APC-free
T3101 6609-6615 NN denotes system
T3102 6616-6618 IN denotes by
T3103 6619-6630 NN denotes stimulation
T3104 6631-6635 IN denotes with
T3105 6636-6644 JJ denotes anti-CD3
T3106 6645-6648 CC denotes and
T3107 6649-6658 JJ denotes anti-CD28
T3108 6659-6669 NN denotes antibodies
T3109 6670-6672 IN denotes in
T3110 6673-6676 DT denotes the
T3111 6677-6685 NN denotes presence
T3112 6686-6688 IN denotes of
T3113 6689-6694 NN denotes IL-12
T3114 6695-6703 VB denotes resulted
T3115 6704-6706 IN denotes in
T3116 6707-6722 JJ denotes IFN-γ-producing
T3117 6723-6726 NN denotes Th1
T3118 6727-6732 NN denotes cells
T3119 6732-6733 -COMMA- denotes ,
T3120 6734-6735 DT denotes a
T3121 6736-6746 NN denotes proportion
T3122 6747-6749 IN denotes of
T3123 6750-6755 WDT denotes which
T3124 6756-6766 VB denotes coproduced
T3125 6767-6772 NN denotes IL-10
T3126 6772-6773 -COMMA- denotes ,
T3127 6774-6776 IN denotes as
T3128 6777-6780 VB denotes did
T3129 6781-6784 NN denotes Th2
T3130 6785-6790 NN denotes cells
T3131 6791-6800 VB denotes resulting
T3132 6801-6805 IN denotes from
T3133 6806-6813 NN denotes culture
T3134 6814-6816 IN denotes in
T3135 6817-6821 NN denotes IL-4
T3136 6822-6823 -LRB- denotes (
T3137 6823-6833 NN denotes Figure S1B
T3138 6833-6834 -RRB- denotes )
T3139 6836-6838 TO denotes To
T3140 6839-6850 VB denotes investigate
T3141 6851-6858 IN denotes whether
T3142 6859-6862 DT denotes the
T3143 6863-6867 NN denotes lack
T3144 6868-6870 IN denotes of
T3145 6871-6876 NN denotes IL-10
T3146 6877-6885 VB denotes produced
T3147 6886-6888 IN denotes by
T3148 6889-6892 NN denotes Th1
T3149 6893-6898 NN denotes cells
T3150 6899-6907 VB denotes resulted
T3151 6908-6912 IN denotes from
T3152 6913-6923 NN denotes inhibition
T3153 6924-6926 IN denotes of
T3154 6927-6932 NN denotes IL-10
T3155 6933-6943 NN denotes production
T3156 6944-6946 IN denotes by
T3157 6947-6950 NN denotes DCs
T3158 6951-6954 CC denotes and
T3159 6955-6959 JJ denotes high
T3160 6960-6967 NN denotes antigen
T3161 6968-6972 NN denotes dose
T3162 6973-6975 CC denotes or
T3163 6976-6989 RB denotes alternatively
T3164 6990-6998 VB denotes required
T3165 6999-7004 NN denotes IL-12
T3166 7004-7005 -COMMA- denotes ,
T3167 7006-7008 PRP denotes we
T3168 7009-7017 VB denotes cultured
T3169 7018-7023 JJ denotes naive
T3170 7024-7028 JJ denotes CD4+
T3171 7029-7036 NN denotes T cells
T3172 7037-7041 IN denotes with
T3173 7042-7052 VB denotes increasing
T3174 7053-7058 NN denotes doses
T3175 7059-7061 IN denotes of
T3176 7062-7069 NN denotes antigen
T3177 7070-7079 VB denotes presented
T3178 7080-7082 IN denotes by
T3179 7083-7085 NN denotes DC
T3180 7086-7088 IN denotes in
T3181 7089-7092 DT denotes the
T3182 7093-7101 NN denotes presence
T3183 7102-7104 IN denotes of
T3184 7105-7110 NN denotes IL-12
T3185 7112-7114 IN denotes At
T3186 7115-7118 JJ denotes low
T3187 7119-7124 NN denotes doses
T3188 7125-7127 IN denotes of
T3189 7128-7135 NN denotes antigen
T3190 7135-7136 -COMMA- denotes ,
T3191 7137-7142 NN denotes IL-12
T3192 7143-7152 VB denotes abrogated
T3193 7153-7156 DT denotes the
T3194 7157-7168 NN denotes development
T3195 7169-7171 IN denotes of
T3196 7172-7175 NN denotes Th2
T3197 7176-7181 NN denotes cells
T3198 7182-7185 CC denotes and
T3199 7186-7193 VB denotes induced
T3200 7194-7199 NN denotes IFN-γ
T3201 7200-7210 NN denotes expression
T3202 7211-7214 CC denotes but
T3203 7215-7219 RB denotes only
T3204 7220-7223 JJ denotes low
T3205 7224-7230 NN denotes levels
T3206 7231-7233 IN denotes of
T3207 7234-7239 NN denotes IL-10
T3208 7240-7250 NN denotes expression
T3209 7250-7251 -COMMA- denotes ,
T3210 7252-7262 VB denotes suggesting
T3211 7263-7267 IN denotes that
T3212 7268-7273 NN denotes IL-12
T3213 7274-7277 FW denotes per
T3214 7278-7280 FW denotes se
T3215 7281-7284 VB denotes was
T3216 7285-7288 RB denotes not
T3217 7289-7299 JJ denotes sufficient
T3218 7300-7302 TO denotes to
T3219 7303-7309 VB denotes induce
T3220 7310-7321 JJ denotes significant
T3221 7322-7327 NN denotes IL-10
T3222 7328-7338 NN denotes production
T3223 7339-7341 IN denotes in
T3224 7342-7345 NN denotes Th1
T3225 7346-7351 NN denotes cells
T3226 7352-7353 -LRB- denotes (
T3227 7353-7362 NN denotes Figure 1A
T3228 7362-7363 -RRB- denotes )
T3229 7365-7375 RB denotes Strikingly
T3230 7375-7376 -COMMA- denotes ,
T3231 7377-7379 IN denotes as
T3232 7380-7383 DT denotes the
T3233 7384-7391 NN denotes antigen
T3234 7392-7396 NN denotes dose
T3235 7397-7400 VB denotes was
T3236 7401-7410 VB denotes increased
T3237 7410-7411 -COMMA- denotes ,
T3238 7412-7415 NN denotes Th1
T3239 7416-7427 NN denotes populations
T3240 7428-7434 VB denotes driven
T3241 7435-7439 IN denotes with
T3242 7440-7445 NN denotes IL-12
T3243 7446-7449 RB denotes now
T3244 7450-7459 VB denotes contained
T3245 7460-7466 JJ denotes higher
T3246 7467-7474 NN denotes numbers
T3247 7475-7477 IN denotes of
T3248 7478-7493 JJ denotes IL-10-producing
T3249 7494-7499 NN denotes cells
T3250 7500-7501 -LRB- denotes (
T3251 7501-7510 NN denotes Figure 1A
T3252 7510-7511 -RRB- denotes )
T3253 7512-7515 CC denotes and
T3254 7516-7524 VB denotes produced
T3255 7525-7529 JJ denotes more
T3256 7530-7535 NN denotes IL-10
T3257 7536-7543 NN denotes protein
T3258 7544-7548 IN denotes upon
T3259 7549-7562 NN denotes restimulation
T3260 7563-7564 -LRB- denotes (
T3261 7564-7571 NN denotes Figures
T3262 7572-7574 NN denotes 1A
T3263 7575-7578 CC denotes and
T3264 7579-7581 NN denotes 1B
T3265 7581-7582 -RRB- denotes )
T3266 7584-7588 RB denotes Thus
T3267 7588-7589 -COMMA- denotes ,
T3268 7590-7593 DT denotes the
T3269 7594-7605 NN denotes development
T3270 7606-7608 IN denotes of
T3271 7609-7612 NN denotes Th1
T3272 7613-7618 NN denotes cells
T3273 7619-7628 VB denotes producing
T3274 7629-7634 NN denotes IL-10
T3275 7635-7643 VB denotes required
T3276 7644-7648 CC denotes both
T3277 7649-7654 NN denotes IL-12
T3278 7655-7658 CC denotes and
T3279 7659-7663 JJ denotes high
T3280 7664-7669 NN denotes doses
T3281 7670-7672 IN denotes of
T3282 7673-7680 NN denotes antigen
T3283 7682-7685 NN denotes Th1
T3284 7686-7691 NN denotes cells
T3285 7692-7706 VB denotes differentiated
T3286 7707-7709 TO denotes to
T3287 7710-7717 VB denotes produce
T3288 7718-7723 JJ denotes large
T3289 7724-7731 NN denotes amounts
T3290 7732-7734 IN denotes of
T3291 7735-7740 NN denotes IL-10
T3292 7741-7744 CC denotes and
T3293 7745-7750 NN denotes IFN-γ
T3294 7751-7754 CC denotes and
T3295 7755-7759 VB denotes lost
T3296 7760-7774 NN denotes their capacity
T3297 7775-7777 TO denotes to
T3298 7778-7785 VB denotes produce
T3299 7786-7790 NN denotes IL-2
T3300 7791-7792 -LRB- denotes (
T3301 7792-7801 NN denotes Figure 1B
T3302 7801-7802 -RRB- denotes )
T3303 7804-7811 IN denotes Because
T3304 7812-7815 DT denotes the
T3305 7816-7824 NN denotes presence
T3306 7825-7827 IN denotes of
T3307 7828-7833 NN denotes IL-12
T3308 7834-7841 VB denotes reduced
T3309 7842-7845 DT denotes the
T3310 7846-7859 NN denotes proliferation
T3311 7860-7862 IN denotes of
T3312 7863-7867 JJ denotes CD4+
T3313 7868-7875 NN denotes T cells
T3314 7876-7878 IN denotes at
T3315 7879-7883 CC denotes both
T3316 7884-7888 JJ denotes high
T3317 7889-7896 NN denotes and low
T3318 7897-7904 NN denotes antigen
T3319 7905-7910 NN denotes doses
T3320 7911-7912 -LRB- denotes (
T3321 7912-7917 JJ denotes Table
T3322 7918-7920 NN denotes S1
T3323 7920-7921 -RRB- denotes )
T3324 7921-7922 -COMMA- denotes ,
T3325 7923-7926 CC denotes and
T3326 7927-7931 RB denotes only
T3327 7932-7935 DT denotes the
T3328 7936-7942 JJ denotes former
T3329 7943-7949 VB denotes showed
T3330 7950-7955 NN denotes IL-10
T3331 7956-7966 NN denotes production
T3332 7966-7967 -COMMA- denotes ,
T3333 7968-7971 DT denotes the
T3334 7972-7983 NN denotes development
T3335 7984-7986 IN denotes of
T3336 7987-7991 JJ denotes high
T3337 7992-8007 JJ denotes IL-10-producing
T3338 8008-8016 NN denotes cells is
T3339 8017-8021 RB denotes most
T3340 8022-8028 RB denotes likely
T3341 8029-8032 RB denotes not
T3342 8033-8040 JJ denotes related
T3343 8041-8043 TO denotes to
T3344 8044-8051 JJ denotes limited
T3345 8052-8056 NN denotes IL-2
T3346 8058-8063 JJ denotes Naive
T3347 8064-8068 JJ denotes CD4+
T3348 8069-8076 NN denotes T cells
T3349 8077-8081 IN denotes from
T3350 8082-8114 JJ denotes DO11.10/recombination-activating
T3351 8115-8119 NN denotes gene
T3352 8120-8121 CD denotes 1
T3353 8122-8123 -LRB- denotes (
T3354 8123-8127 NN denotes Rag1
T3355 8127-8128 -RRB- denotes )
T3356 8128-8138 JJ denotes -deficient
T3357 8139-8146 NN denotes animals
T3358 8146-8147 -COMMA- denotes ,
T3359 8148-8156 VB denotes cultured
T3360 8157-8161 IN denotes with
T3361 8162-8166 JJ denotes high
T3362 8167-8172 NN denotes doses
T3363 8173-8175 IN denotes of
T3364 8176-8183 NN denotes antigen
T3365 8184-8186 IN denotes in
T3366 8187-8190 DT denotes the
T3367 8191-8199 NN denotes presence
T3368 8200-8202 IN denotes of
T3369 8203-8208 NN denotes IL-12
T3370 8208-8209 -COMMA- denotes ,
T3371 8210-8214 RB denotes also
T3372 8215-8223 VB denotes resulted
T3373 8224-8226 IN denotes in
T3374 8227-8232 NN denotes IL-10
T3375 8233-8243 NN denotes expression
T3376 8244-8246 IN denotes by
T3377 8247-8250 NN denotes Th1
T3378 8251-8256 NN denotes cells
T3379 8256-8257 -COMMA- denotes ,
T3380 8258-8265 VB denotes showing
T3381 8266-8270 IN denotes that
T3382 8271-8275 DT denotes this
T3383 8276-8286 NN denotes expression
T3384 8287-8290 VB denotes was
T3385 8291-8294 RB denotes not
T3386 8295-8304 JJ denotes dependent
T3387 8305-8307 IN denotes on
T3388 8308-8311 DT denotes the
T3389 8312-8320 NN denotes presence
T3390 8321-8323 IN denotes of
T3391 8324-8332 NN denotes effector
T3392 8333-8335 CC denotes or
T3393 8336-8342 NN denotes memory
T3394 8343-8350 NN denotes T cells
T3395 8351-8353 CC denotes or
T3396 8354-8358 NN denotes Treg
T3397 8359-8364 NN denotes cells
T3398 8365-8366 -LRB- denotes (
T3399 8366-8375 NN denotes Figure S2
T3400 8375-8376 -RRB- denotes )
T3401 8378-8386 IN denotes Although
T3402 8387-8389 PRP denotes it
T3403 8390-8393 VB denotes has
T3404 8394-8398 VB denotes been
T3405 8399-8408 VB denotes suggested
T3406 8409-8413 IN denotes that
T3407 8414-8419 NN denotes TGF-β
T3408 8420-8423 MD denotes can
T3409 8424-8430 VB denotes induce
T3410 8431-8436 NN denotes IL-10
T3411 8437-8439 IN denotes in
T3412 8440-8444 JJ denotes CD4+
T3413 8445-8452 NN denotes T cells
T3414 8453-8454 -LRB- denotes (
T3415 8454-8460 NNP denotes Kitani
T3416 8461-8467 NNP denotes et al.
T3417 8467-8468 -COMMA- denotes ,
T3418 8469-8473 CD denotes 2003
T3419 8473-8474 -COLON- denotes ;
T3420 8475-8482 NNP denotes Schiott
T3421 8483-8489 FW denotes et al.
T3422 8489-8490 -COMMA- denotes ,
T3423 8491-8495 CD denotes 2000
T3424 8495-8496 -RRB- denotes )
T3425 8496-8497 -COMMA- denotes ,
T3426 8498-8500 PRP denotes we
T3427 8501-8506 VB denotes found
T3428 8507-8511 IN denotes that
T3429 8512-8514 IN denotes in
T3430 8515-8525 VB denotes developing
T3431 8526-8529 NN denotes Th1
T3432 8530-8533 CC denotes and
T3433 8534-8537 NN denotes Th2
T3434 8538-8543 NN denotes cells
T3435 8544-8548 DT denotes this
T3436 8549-8552 VB denotes was
T3437 8553-8556 RB denotes not
T3438 8557-8560 DT denotes the
T3439 8561-8565 NN denotes case
T3440 8566-8567 -LRB- denotes (
T3441 8567-8571 NN denotes data
T3442 8572-8575 RB denotes not
T3443 8576-8581 VB denotes shown
T3444 8581-8582 -RRB- denotes )
T3445 8584-8586 IN denotes In
T3446 8587-8591 NN denotes fact
T3447 8591-8592 -COMMA- denotes ,
T3448 8593-8607 NN denotes neutralization
T3449 8608-8610 IN denotes of
T3450 8611-8616 NN denotes TGF-β
T3451 8617-8620 VB denotes led
T3452 8621-8623 TO denotes to
T3453 8624-8633 VB denotes increased
T3454 8634-8639 NN denotes IL-10
T3455 8640-8650 NN denotes production
T3456 8651-8653 IN denotes by
T3457 8654-8658 DT denotes both
T3458 8659-8665 NN denotes T cell
T3459 8666-8673 NN denotes subsets
T3460 8674-8675 -LRB- denotes (
T3461 8675-8684 NN denotes Figure S3
T3462 8684-8685 -RRB- denotes )
T3463 8687-8691 RB denotes Thus
T3464 8691-8692 -COMMA- denotes ,
T3465 8693-8696 DT denotes the
T3466 8697-8708 NN denotes development
T3467 8709-8711 IN denotes of
T3468 8712-8727 JJ denotes IL-10-producing
T3469 8728-8731 NN denotes Th1
T3470 8732-8737 NN denotes cells
T3471 8738-8742 RB denotes only
T3472 8743-8751 VB denotes depended
T3473 8752-8754 IN denotes on
T3474 8755-8758 DT denotes the
T3475 8759-8767 NN denotes presence
T3476 8768-8770 IN denotes of
T3477 8771-8776 NN denotes IL-12
T3478 8777-8785 RB denotes together
T3479 8786-8790 IN denotes with
T3480 8791-8795 JJ denotes high
T3481 8796-8803 NN denotes antigen
T3482 8804-8808 NN denotes dose
T3483 8809-8812 CC denotes and
T3484 8813-8816 RB denotes not
T3485 8817-8819 IN denotes on
T3486 8820-8825 JJ denotes other
T3487 8826-8833 JJ denotes soluble
T3488 8834-8841 NN denotes factors
T3489 8842-8846 JJ denotes such
T3490 8847-8849 IN denotes as
T3491 8850-8854 NN denotes IL-2
T3492 8855-8857 CC denotes or
T3493 8858-8863 NN denotes TGF-β
T3494 8864-8866 CC denotes or
T3495 8867-8869 IN denotes on
T3496 8870-8873 DT denotes the
T3497 8874-8882 NN denotes presence
T3498 8883-8885 IN denotes of
T3499 8886-8891 JJ denotes other
T3500 8892-8898 NN denotes T cell
T3501 8899-8904 NN denotes types
T5036 8907-8912 NN denotes IL-10
T5037 8913-8923 NN denotes Production
T5038 8924-8926 IN denotes by
T5039 8927-8930 NN denotes Th1
T5040 8931-8936 NN denotes Cells
T5041 8937-8939 VB denotes Is
T5042 8940-8949 JJ denotes Dependent
T5043 8950-8952 IN denotes on
T5044 8953-8958 NN denotes STAT4
T5045 8959-8962 CC denotes but
T5046 8963-8966 RB denotes Not
T5047 8967-8969 IN denotes on
T5048 8970-8975 NN denotes STAT6
T5049 8975-8976 -COMMA- denotes ,
T5050 8977-8982 NN denotes IFN-γ
T5051 8982-8983 -COMMA- denotes ,
T5052 8984-8986 CC denotes or
T5053 8987-8991 NN denotes IL-4
T5054 8992-9001 NN denotes Signaling
T5055 9002-9004 TO denotes To
T5056 9005-9012 RB denotes further
T5057 9013-9022 VB denotes elucidate
T5058 9023-9026 DT denotes the
T5059 9027-9037 NN denotes mechanisms
T5060 9038-9046 VB denotes required
T5061 9047-9050 IN denotes for
T5062 9051-9054 DT denotes the
T5063 9055-9066 NN denotes development
T5064 9067-9069 IN denotes of
T5065 9070-9073 NN denotes Th1
T5066 9074-9079 NN denotes cells
T5067 9080-9089 VB denotes producing
T5068 9090-9095 NN denotes IL-10
T5069 9095-9096 -COMMA- denotes ,
T5070 9097-9099 PRP denotes we
T5071 9100-9112 VB denotes investigated
T5072 9113-9116 DT denotes the
T5073 9117-9121 NN denotes role
T5074 9122-9124 IN denotes of
T5075 9125-9130 NN denotes STAT4
T5076 9130-9131 -COMMA- denotes ,
T5077 9132-9135 CD denotes one
T5078 9136-9138 IN denotes of
T5079 9139-9142 DT denotes the
T5080 9143-9152 NN denotes signaling
T5081 9153-9161 NN denotes pathways
T5082 9162-9171 VB denotes activated
T5083 9172-9174 IN denotes by
T5084 9175-9180 NN denotes IL-12
T5085 9181-9182 -LRB- denotes (
T5086 9182-9188 NNP denotes Murphy
T5087 9189-9195 NNP denotes et al.
T5088 9195-9196 -COMMA- denotes ,
T5089 9197-9201 CD denotes 2000
T5090 9201-9202 -RRB- denotes )
T5091 9204-9209 JJ denotes Naive
T5092 9210-9214 JJ denotes CD4+
T5093 9215-9222 NN denotes D011.10
T5094 9223-9230 NN denotes T cells
T5095 9231-9240 JJ denotes deficient
T5096 9241-9243 IN denotes in
T5097 9244-9249 NN denotes STAT4
T5098 9250-9251 -LRB- denotes (
T5099 9251-9257 NNP denotes Ouyang
T5100 9258-9264 NNP denotes et al.
T5101 9264-9265 -COMMA- denotes ,
T5102 9266-9270 CD denotes 1998
T5103 9270-9271 -RRB- denotes )
T5104 9272-9276 VB denotes were
T5105 9277-9285 VB denotes cultured
T5106 9286-9288 IN denotes in
T5107 9289-9292 DT denotes the
T5108 9293-9301 NN denotes presence
T5109 9302-9304 IN denotes of
T5110 9305-9310 NN denotes IL-12
T5111 9311-9314 CC denotes and
T5112 9315-9318 NN denotes OVA
T5113 9320-9325 RB denotes Again
T5114 9325-9326 -COMMA- denotes ,
T5115 9327-9342 JJ denotes IL-10-producing
T5116 9343-9346 NN denotes Th1
T5117 9347-9352 NN denotes cells
T5118 9353-9357 VB denotes were
T5119 9358-9372 VB denotes differentiated
T5120 9373-9375 IN denotes at
T5121 9376-9379 DT denotes the
T5122 9380-9384 JJ denotes high
T5123 9385-9392 NN denotes antigen
T5124 9393-9397 NN denotes dose
T5125 9398-9400 IN denotes in
T5126 9401-9404 DT denotes the
T5127 9405-9413 NN denotes presence
T5128 9414-9416 IN denotes of
T5129 9417-9422 NN denotes IL-12
T5130 9423-9425 IN denotes in
T5131 9426-9433 NN denotes DO11.10
T5132 9434-9441 NN denotes T cells
T5133 9442-9443 -LRB- denotes (
T5134 9443-9452 NN denotes Figure 2A
T5135 9452-9453 -RRB- denotes )
T5136 9455-9457 IN denotes In
T5137 9458-9466 NN denotes contrast
T5138 9466-9467 -COMMA- denotes ,
T5139 9468-9470 IN denotes in
T5140 9471-9474 DT denotes the
T5141 9475-9482 NN denotes absence
T5142 9483-9485 IN denotes of
T5143 9486-9491 NN denotes STAT4
T5144 9491-9492 -COMMA- denotes ,
T5145 9493-9496 DT denotes the
T5146 9497-9507 NN denotes percentage
T5147 9508-9510 IN denotes of
T5148 9511-9516 NN denotes cells
T5149 9517-9527 VB denotes expressing
T5150 9528-9533 NN denotes IFN-γ
T5151 9534-9537 VB denotes was
T5152 9538-9550 RB denotes dramatically
T5153 9551-9561 VB denotes diminished
T5154 9562-9564 IN denotes as
T5155 9565-9573 VB denotes expected
T5156 9574-9577 CC denotes and
T5157 9578-9586 VB denotes resulted
T5158 9587-9589 IN denotes in
T5159 9590-9592 DT denotes an
T5160 9593-9601 NN denotes increase
T5161 9602-9604 IN denotes in
T5162 9605-9608 DT denotes the
T5163 9609-9619 NN denotes percentage
T5164 9620-9622 IN denotes of
T5165 9623-9628 NN denotes cells
T5166 9629-9639 VB denotes expressing
T5167 9640-9644 NN denotes IL-4
T5168 9644-9645 -COMMA- denotes ,
T5169 9646-9649 CC denotes but
T5170 9650-9653 RB denotes not
T5171 9654-9659 NN denotes IL-10
T5172 9660-9661 -LRB- denotes (
T5173 9661-9670 NN denotes Figure 2A
T5174 9670-9671 -RRB- denotes )
T5175 9671-9672 -COMMA- denotes ,
T5176 9673-9683 VB denotes suggesting
T5177 9684-9688 IN denotes that
T5178 9689-9694 NN denotes STAT4
T5179 9695-9706 VB denotes contributes
T5180 9707-9709 TO denotes to
T5181 9710-9715 NN denotes IL-10
T5182 9716-9726 NN denotes expression
T5183 9727-9729 IN denotes by
T5184 9730-9733 NN denotes Th1
T5185 9734-9739 NN denotes cells
T5186 9741-9748 IN denotes Because
T5187 9749-9754 NN denotes IL-10
T5188 9755-9765 NN denotes expression
T5189 9766-9768 VB denotes is
T5190 9769-9779 VB denotes associated
T5191 9780-9784 IN denotes with
T5192 9785-9787 DT denotes an
T5193 9788-9800 JJ denotes IL-4-induced
T5194 9801-9804 NN denotes Th2
T5195 9805-9809 NN denotes cell
T5196 9810-9819 NN denotes phenotype
T5197 9819-9820 -COMMA- denotes ,
T5198 9821-9823 PRP denotes we
T5199 9824-9836 VB denotes investigated
T5200 9837-9844 IN denotes whether
T5201 9845-9848 DT denotes the
T5202 9849-9864 NN denotes differentiation
T5203 9865-9867 IN denotes of
T5204 9868-9871 DT denotes the
T5205 9872-9887 JJ denotes IL-10-producing
T5206 9888-9891 NN denotes Th1
T5207 9892-9897 NN denotes cells
T5208 9898-9906 VB denotes depended
T5209 9907-9909 IN denotes on
T5210 9910-9919 NN denotes signaling
T5211 9920-9927 IN denotes through
T5212 9928-9931 DT denotes the
T5213 9932-9936 NN denotes IL-4
T5214 9937-9945 NN denotes receptor
T5215 9946-9949 IN denotes via
T5216 9950-9955 NN denotes STAT6
T5217 9956-9966 NN denotes activation
T5218 9967-9968 -LRB- denotes (
T5219 9968-9976 NNP denotes Glimcher
T5220 9977-9980 CC denotes and
T5221 9981-9987 NNP denotes Murphy
T5222 9987-9988 -COMMA- denotes ,
T5223 9989-9993 CD denotes 2000
T5224 9993-9994 -COLON- denotes ;
T5225 9995-10001 NNP denotes Murphy
T5226 10002-10008 FW denotes et al.
T5227 10008-10009 -COMMA- denotes ,
T5228 10010-10014 CD denotes 2000
T5229 10014-10015 -RRB- denotes )
T5230 10017-10020 DT denotes The
T5231 10021-10028 NN denotes absence
T5232 10029-10031 IN denotes of
T5233 10032-10037 NN denotes STAT6
T5234 10038-10041 VB denotes did
T5235 10042-10045 RB denotes not
T5236 10046-10052 VB denotes impair
T5237 10053-10056 DT denotes the
T5238 10057-10072 NN denotes differentiation
T5239 10073-10075 IN denotes of
T5240 10076-10091 JJ denotes IL-10-producing
T5241 10092-10095 NN denotes Th1
T5242 10096-10101 NN denotes cells
T5243 10102-10104 IN denotes in
T5244 10105-10108 DT denotes the
T5245 10109-10117 NN denotes presence
T5246 10118-10120 IN denotes of
T5247 10121-10126 NN denotes IL-12
T5248 10127-10130 CC denotes and
T5249 10131-10134 NN denotes OVA
T5250 10135-10136 -LRB- denotes (
T5251 10136-10145 NN denotes Figure 2A
T5252 10145-10146 -RRB- denotes )
T5253 10148-10150 IN denotes In
T5254 10151-10155 NN denotes fact
T5255 10155-10156 -COMMA- denotes ,
T5256 10157-10158 DT denotes a
T5257 10159-10165 JJ denotes higher
T5258 10166-10176 NN denotes percentage
T5259 10177-10179 IN denotes of
T5260 10180-10195 JJ denotes STAT6-deficient
T5261 10196-10201 NN denotes cells
T5262 10202-10210 VB denotes compared
T5263 10211-10215 IN denotes with
T5264 10216-10218 JJ denotes WT
T5265 10219-10224 NN denotes cells
T5266 10225-10233 VB denotes produced
T5267 10234-10238 CC denotes both
T5268 10239-10244 NN denotes IL-10
T5269 10245-10248 CC denotes and
T5270 10249-10254 NN denotes IFN-γ
T5271 10255-10256 -LRB- denotes (
T5272 10256-10265 NN denotes Figure 2A
T5273 10265-10266 -RRB- denotes )
T5274 10266-10267 -COMMA- denotes ,
T5275 10268-10273 WDT denotes which
T5276 10274-10277 MD denotes may
T5277 10278-10280 VB denotes be
T5278 10281-10284 DT denotes the
T5279 10285-10291 NN denotes result
T5280 10292-10294 IN denotes of
T5281 10295-10298 DT denotes the
T5282 10299-10303 NN denotes loss
T5283 10304-10306 IN denotes of
T5284 10307-10310 NN denotes Th2
T5285 10311-10315 NN denotes cell
T5286 10316-10323 NN denotes control
T5287 10324-10328 IN denotes over
T5288 10329-10330 DT denotes a
T5289 10331-10334 NN denotes Th1
T5290 10335-10339 NN denotes cell
T5291 10340-10348 NN denotes response
T5292 10350-10352 IN denotes As
T5293 10353-10361 VB denotes expected
T5294 10361-10362 -COMMA- denotes ,
T5295 10363-10367 NN denotes lack
T5296 10368-10370 IN denotes of
T5297 10371-10376 NN denotes STAT6
T5298 10377-10386 VB denotes abrogated
T5299 10387-10391 CC denotes both
T5300 10392-10396 NN denotes IL-4
T5301 10397-10400 CC denotes and
T5302 10401-10406 NN denotes IL-10
T5303 10407-10417 NN denotes production
T5304 10418-10420 IN denotes by
T5305 10421-10428 NN denotes T cells
T5306 10429-10438 VB denotes developed
T5307 10439-10443 IN denotes with
T5308 10444-10448 NN denotes IL-4
T5309 10449-10451 CC denotes or
T5310 10452-10456 IN denotes with
T5311 10457-10460 JJ denotes low
T5312 10461-10468 NN denotes antigen
T5313 10469-10473 NN denotes dose
T5314 10474-10475 -LRB- denotes (
T5315 10475-10482 NN denotes Figures
T5316 10483-10485 NN denotes 2B
T5317 10486-10489 CC denotes and
T5318 10490-10492 NN denotes 2C
T5319 10492-10493 -RRB- denotes )
T5320 10495-10502 RB denotes However
T5321 10502-10503 -COMMA- denotes ,
T5322 10504-10506 IN denotes in
T5323 10507-10510 DT denotes the
T5324 10511-10518 NN denotes absence
T5325 10519-10521 IN denotes of
T5326 10522-10527 NN denotes STAT4
T5327 10528-10537 NN denotes signaling
T5328 10537-10538 -COMMA- denotes ,
T5329 10539-10544 NN denotes IL-10
T5330 10545-10548 CC denotes and
T5331 10549-10553 NN denotes IL-4
T5332 10554-10564 NN denotes production
T5333 10565-10567 IN denotes by
T5334 10568-10571 NN denotes Th2
T5335 10572-10577 NN denotes cells
T5336 10578-10581 VB denotes was
T5337 10582-10584 IN denotes if
T5338 10585-10593 NN denotes anything
T5339 10594-10603 VB denotes increased
T5340 10604-10605 -LRB- denotes (
T5341 10605-10612 NN denotes Figures
T5342 10613-10615 NN denotes 2B
T5343 10616-10619 CC denotes and
T5344 10620-10622 NN denotes 2C
T5345 10622-10623 -RRB- denotes )
T5346 10625-10629 RB denotes Thus
T5347 10629-10630 -COMMA- denotes ,
T5348 10631-10633 IN denotes in
T5349 10634-10642 NN denotes contrast
T5350 10643-10645 TO denotes to
T5351 10646-10650 WP denotes what
T5352 10651-10654 VB denotes was
T5353 10655-10663 VB denotes observed
T5354 10664-10669 IN denotes under
T5355 10670-10673 NN denotes Th1
T5356 10674-10684 NN denotes conditions
T5357 10684-10685 -COMMA- denotes ,
T5358 10686-10691 NN denotes IL-10
T5359 10692-10702 NN denotes expression
T5360 10703-10705 IN denotes by
T5361 10706-10709 NN denotes Th2
T5362 10710-10715 NN denotes cells
T5363 10716-10724 VB denotes depended
T5364 10725-10727 IN denotes on
T5365 10728-10733 NN denotes STAT6
T5366 10733-10734 -COMMA- denotes ,
T5367 10735-10738 CC denotes but
T5368 10739-10742 RB denotes not
T5369 10743-10745 IN denotes on
T5370 10746-10751 NN denotes STAT4
T5371 10751-10752 -COMMA- denotes ,
T5372 10753-10762 NN denotes signaling
T5373 10763-10764 -LRB- denotes (
T5374 10764-10771 NN denotes Figures
T5375 10772-10774 NN denotes 2B
T5376 10775-10778 CC denotes and
T5377 10779-10781 NN denotes 2C
T5378 10781-10782 -RRB- denotes )
T5379 10784-10786 TO denotes To
T5380 10787-10798 VB denotes investigate
T5381 10799-10806 IN denotes whether
T5382 10807-10810 DT denotes the
T5383 10811-10820 NN denotes inability
T5384 10821-10823 IN denotes of
T5385 10824-10839 JJ denotes STAT4-deficient
T5386 10840-10847 NN denotes T cells
T5387 10848-10850 TO denotes to
T5388 10851-10858 VB denotes produce
T5389 10859-10864 NN denotes IL-10
T5390 10865-10870 MD denotes might
T5391 10871-10873 VB denotes be
T5392 10874-10877 JJ denotes due
T5393 10878-10880 TO denotes to
T5394 10881-10884 DT denotes the
T5395 10885-10892 NN denotes absence
T5396 10893-10895 IN denotes of
T5397 10896-10901 NN denotes IFN-γ
T5398 10901-10902 -COMMA- denotes ,
T5399 10903-10905 IN denotes as
T5400 10906-10915 VB denotes suggested
T5401 10916-10922 IN denotes before
T5402 10923-10924 -LRB- denotes (
T5403 10924-10928 NNP denotes Shaw
T5404 10929-10935 NNP denotes et al.
T5405 10935-10936 -COMMA- denotes ,
T5406 10937-10941 CD denotes 2006
T5407 10941-10942 -RRB- denotes )
T5408 10942-10943 -COMMA- denotes ,
T5409 10944-10946 PRP denotes we
T5410 10947-10961 VB denotes differentiated
T5411 10962-10969 NN denotes DO11.10
T5412 10970-10972 CC denotes or
T5413 10973-10980 NN denotes DO11.10
T5414 10981-10996 JJ denotes IFN-γ-deficient
T5415 10997-11002 JJ denotes naive
T5416 11003-11007 JJ denotes CD4+
T5417 11008-11015 NN denotes T cells
T5418 11016-11018 IN denotes in
T5419 11019-11022 DT denotes the
T5420 11023-11031 NN denotes presence
T5421 11032-11034 IN denotes of
T5422 11035-11040 NN denotes IL-12
T5423 11041-11044 CC denotes and
T5424 11045-11055 VB denotes increasing
T5425 11056-11061 NN denotes doses
T5426 11062-11064 IN denotes of
T5427 11065-11068 NN denotes OVA
T5428 11070-11073 DT denotes The
T5429 11074-11083 NN denotes secretion
T5430 11084-11086 IN denotes of
T5431 11087-11092 NN denotes IL-10
T5432 11093-11095 IN denotes as
T5433 11096-11103 VB denotes induced
T5434 11104-11106 IN denotes by
T5435 11107-11111 JJ denotes high
T5436 11112-11119 NN denotes antigen
T5437 11120-11124 NN denotes dose
T5438 11124-11125 -COMMA- denotes ,
T5439 11126-11129 CC denotes and
T5440 11130-11135 NN denotes IL-12
T5441 11136-11139 VB denotes was
T5442 11140-11143 RB denotes not
T5443 11144-11152 VB denotes affected
T5444 11153-11155 IN denotes by
T5445 11156-11158 DT denotes an
T5446 11159-11166 NN denotes absence
T5447 11167-11169 IN denotes of
T5448 11170-11175 NN denotes IFN-γ
T5449 11176-11177 -LRB- denotes (
T5450 11177-11186 NN denotes Figure 2D
T5451 11186-11187 -RRB- denotes )
T5452 11187-11188 -COMMA- denotes ,
T5453 11189-11196 VB denotes showing
T5454 11197-11201 IN denotes that
T5455 11202-11205 DT denotes the
T5456 11206-11216 NN denotes expression
T5457 11217-11225 NN denotes of IL-10
T5458 11226-11228 IN denotes by
T5459 11229-11232 NN denotes Th1
T5460 11233-11238 NN denotes cells
T5461 11239-11241 VB denotes is
T5462 11242-11253 JJ denotes independent
T5463 11254-11256 IN denotes of
T5464 11257-11262 NN denotes IFN-γ
T5465 11264-11266 IN denotes In
T5466 11267-11270 DT denotes the
T5467 11271-11278 NN denotes absence
T5468 11279-11281 IN denotes of
T5469 11282-11287 NN denotes IFN-γ
T5470 11287-11288 -COMMA- denotes ,
T5471 11289-11291 PRP denotes we
T5472 11292-11300 VB denotes observed
T5473 11301-11303 DT denotes an
T5474 11304-11312 NN denotes increase
T5475 11313-11315 IN denotes in
T5476 11316-11319 DT denotes the
T5477 11320-11328 VB denotes secreted
T5478 11329-11333 NN denotes IL-4
T5479 11334-11336 IN denotes as
T5480 11337-11345 VB denotes expected
T5481 11346-11347 -LRB- denotes (
T5482 11347-11351 NN denotes data
T5483 11352-11355 RB denotes not
T5484 11356-11361 VB denotes shown
T5485 11361-11362 -RRB- denotes )
T5486 11364-11366 PRP denotes We
T5487 11367-11371 RB denotes also
T5488 11372-11378 VB denotes tested
T5489 11379-11382 IN denotes for
T5490 11383-11386 DT denotes any
T5491 11387-11396 JJ denotes potential
T5492 11397-11401 NN denotes role
T5493 11402-11404 IN denotes of
T5494 11405-11409 NN denotes IL-4
T5495 11410-11412 IN denotes in
T5496 11413-11416 DT denotes the
T5497 11417-11428 NN denotes development
T5498 11429-11431 IN denotes of
T5499 11432-11435 NN denotes Th1
T5500 11436-11441 NN denotes cells
T5501 11442-11451 VB denotes producing
T5502 11452-11457 NN denotes IL-10
T5503 11458-11460 IN denotes by
T5504 11461-11470 VB denotes culturing
T5505 11471-11478 NN denotes DO11.10
T5506 11479-11481 CC denotes or
T5507 11482-11489 NN denotes DO11.10
T5508 11490-11504 JJ denotes IL-4-deficient
T5509 11505-11510 JJ denotes naive
T5510 11511-11515 JJ denotes CD4+
T5511 11516-11523 NN denotes T cells
T5512 11524-11528 IN denotes with
T5513 11529-11534 NN denotes IL-12
T5514 11535-11538 CC denotes and
T5515 11539-11549 VB denotes increasing
T5516 11550-11555 NN denotes doses
T5517 11556-11558 IN denotes of
T5518 11559-11566 NN denotes antigen
T5519 11568-11570 IN denotes As
T5520 11571-11579 VB denotes observed
T5521 11580-11582 IN denotes in
T5522 11583-11586 DT denotes the
T5523 11587-11594 NN denotes absence
T5524 11595-11597 IN denotes of
T5525 11598-11603 NN denotes STAT6
T5526 11604-11605 -LRB- denotes (
T5527 11605-11614 NN denotes Figure 2A
T5528 11614-11615 -RRB- denotes )
T5529 11615-11616 -COMMA- denotes ,
T5530 11617-11621 NN denotes IL-4
T5531 11622-11632 NN denotes deficiency
T5532 11633-11636 VB denotes had
T5533 11637-11639 DT denotes no
T5534 11640-11646 NN denotes effect
T5535 11647-11649 IN denotes on
T5536 11650-11653 DT denotes the
T5537 11654-11665 NN denotes development
T5538 11666-11668 IN denotes of
T5539 11669-11672 NN denotes Th1
T5540 11673-11678 NN denotes cells
T5541 11679-11688 VB denotes producing
T5542 11689-11694 NN denotes IL-10
T5543 11695-11696 -LRB- denotes (
T5544 11696-11705 NN denotes Figure 2E
T5545 11705-11706 -RRB- denotes )
T5546 11706-11707 -COMMA- denotes ,
T5547 11708-11711 CC denotes but
T5548 11712-11723 VB denotes compromised
T5549 11724-11727 DT denotes the
T5550 11728-11739 NN denotes development
T5551 11740-11742 IN denotes of
T5552 11743-11746 NN denotes Th2
T5553 11747-11752 NN denotes cells
T5554 11753-11762 VB denotes producing
T5555 11763-11768 NN denotes IL-10
T5556 11769-11770 -LRB- denotes (
T5557 11770-11779 NN denotes Figure 2F
T5558 11779-11780 -RRB- denotes )
T5559 11782-11786 RB denotes Thus
T5560 11786-11787 -COMMA- denotes ,
T5561 11788-11791 PRP-DOLLAR- denotes our
T5562 11792-11796 NN denotes data
T5563 11797-11806 VB denotes suggested
T5564 11807-11811 IN denotes that
T5565 11812-11817 NN denotes IL-10
T5566 11818-11828 NN denotes production
T5567 11829-11831 IN denotes by
T5568 11832-11835 NN denotes Th1
T5569 11836-11838 CC denotes or
T5570 11839-11842 NN denotes Th2
T5571 11843-11848 NN denotes cells
T5572 11849-11852 VB denotes was
T5573 11853-11862 JJ denotes dependent
T5574 11863-11865 IN denotes on
T5575 11866-11869 DT denotes the
T5576 11870-11878 JJ denotes specific
T5577 11879-11888 NN denotes signaling
T5578 11889-11897 NN denotes pathways
T5579 11898-11906 VB denotes required
T5580 11907-11910 IN denotes for
T5581 11911-11916 PRP-DOLLAR- denotes their
T5582 11917-11932 NN denotes differentiation
T5583 11932-11933 -COMMA- denotes ,
T5584 11934-11939 VB denotes given
T5585 11940-11944 IN denotes that
T5586 11945-11950 NN denotes STAT4
T5587 11951-11953 VB denotes is
T5588 11954-11962 VB denotes required
T5589 11963-11966 IN denotes for
T5590 11967-11970 DT denotes the
T5591 11971-11980 NN denotes induction
T5592 11981-11983 IN denotes of
T5593 11984-11989 NN denotes IL-10
T5594 11990-12000 NN denotes production
T5595 12001-12003 IN denotes by
T5596 12004-12007 NN denotes Th1
T5597 12008-12013 NN denotes cells
T5598 12014-12017 CC denotes and
T5599 12018-12023 NN denotes STAT6
T5600 12024-12027 IN denotes for
T5601 12028-12031 NN denotes Th2
T5602 12032-12037 NN denotes cells
T7042 12040-12044 JJ denotes High
T7043 12045-12052 NN denotes Antigen
T7044 12053-12058 NN denotes Doses
T7045 12059-12062 CC denotes and
T7046 12063-12068 NN denotes STAT4
T7047 12069-12072 VB denotes Are
T7048 12073-12081 VB denotes Required
T7049 12082-12085 IN denotes for
T7050 12086-12089 DT denotes the
T7051 12090-12092 NNP denotes In
T7052 12093-12097 NNP denotes Vivo
T7053 12098-12108 NNP denotes Generation
T7054 12109-12111 IN denotes of
T7055 12112-12127 JJ denotes IL-10-Producing
T7056 12128-12131 NN denotes Th1
T7057 12132-12137 NN denotes Cells
T7058 12138-12140 TO denotes To
T7059 12141-12148 VB denotes address
T7060 12149-12152 DT denotes the
T7061 12153-12163 NN denotes mechanisms
T7062 12164-12174 VB denotes regulating
T7063 12175-12180 NN denotes IL-10
T7064 12181-12191 NN denotes production
T7065 12192-12194 IN denotes by
T7066 12195-12198 NN denotes Th1
T7067 12199-12204 NN denotes cells
T7068 12205-12212 FW denotes in vivo
T7069 12212-12213 -COMMA- denotes ,
T7070 12214-12216 PRP denotes we
T7071 12217-12228 VB denotes transferred
T7072 12229-12236 NN denotes DO11.10
T7073 12237-12242 NN denotes cells
T7074 12243-12247 IN denotes into
T7075 12248-12254 NN denotes BALB/c
T7076 12255-12264 NN denotes recipient
T7077 12265-12269 NN denotes mice
T7078 12270-12273 CC denotes and
T7079 12274-12283 VB denotes immunized
T7080 12284-12287 DT denotes the
T7081 12288-12298 NN denotes recipients
T7082 12299-12303 IN denotes with
T7083 12304-12308 RB denotes very
T7084 12309-12313 JJ denotes high
T7085 12314-12319 NN denotes doses
T7086 12320-12322 IN denotes of
T7087 12323-12334 NN denotes OVA-protein
T7088 12335-12339 IN denotes with
T7089 12340-12342 CC denotes or
T7090 12343-12350 IN denotes without
T7091 12351-12356 VB denotes added
T7092 12357-12374 NN denotes lipopolysacharide
T7093 12375-12376 -LRB- denotes (
T7094 12376-12379 NN denotes LPS
T7095 12379-12380 -RRB- denotes )
T7096 12382-12389 NN denotes T cells
T7097 12390-12394 VB denotes were
T7098 12395-12404 VB denotes recovered
T7099 12405-12409 IN denotes from
T7100 12410-12413 DT denotes the
T7101 12414-12422 JJ denotes inguinal
T7102 12423-12428 NN denotes lymph
T7103 12429-12434 NN denotes nodes
T7104 12435-12436 CD denotes 3
T7105 12437-12441 NN denotes days
T7106 12442-12447 IN denotes after
T7107 12448-12455 NN denotes priming
T7108 12456-12459 CC denotes and
T7109 12460-12472 VB denotes restimulated
T7110 12473-12481 FW denotes in vitro
T7111 12482-12486 IN denotes with
T7112 12487-12490 NN denotes OVA
T7113 12491-12498 NN denotes peptide
T7114 12499-12502 IN denotes for
T7115 12503-12505 CD denotes 48
T7116 12506-12508 NN denotes hr
T7117 12510-12514 DT denotes This
T7118 12515-12522 FW denotes in vivo
T7119 12523-12535 NN denotes immunization
T7120 12536-12543 VB denotes induced
T7121 12544-12549 NN denotes IL-10
T7122 12550-12553 CC denotes and
T7123 12554-12559 NN denotes IFN-γ
T7124 12560-12570 NN denotes production
T7125 12570-12571 -COMMA- denotes ,
T7126 12572-12575 CC denotes and
T7127 12576-12579 DT denotes the
T7128 12580-12586 NN denotes amount
T7129 12587-12589 IN denotes of
T7130 12590-12595 NN denotes IL-10
T7131 12596-12606 NN denotes production
T7132 12607-12610 VB denotes was
T7133 12611-12619 VB denotes enhanced
T7134 12620-12622 IN denotes by
T7135 12623-12631 NN denotes addition
T7136 12632-12634 IN denotes of
T7137 12635-12638 NN denotes LPS
T7138 12639-12641 IN denotes in
T7139 12642-12645 DT denotes the
T7140 12646-12658 NN denotes immunization
T7141 12659-12660 -LRB- denotes (
T7142 12660-12669 NN denotes Figure 3A
T7143 12669-12670 -RRB- denotes )
T7144 12671-12674 CC denotes and
T7145 12675-12679 IN denotes with
T7146 12680-12686 JJ denotes higher
T7147 12687-12692 NN denotes doses
T7148 12693-12695 IN denotes of
T7149 12696-12699 NN denotes OVA
T7150 12700-12701 -LRB- denotes (
T7151 12701-12702 CD denotes 3
T7152 12703-12705 NN denotes μM
T7153 12706-12712 IN denotes versus
T7154 12713-12714 CD denotes 1
T7155 12715-12717 NN denotes μM
T7156 12717-12718 -COMMA- denotes ,
T7157 12719-12723 NN denotes data
T7158 12724-12727 RB denotes not
T7159 12728-12733 VB denotes shown
T7160 12733-12734 -RRB- denotes )
T7161 12736-12738 TO denotes To
T7162 12739-12743 VB denotes test
T7163 12744-12747 DT denotes the
T7164 12748-12752 NN denotes role
T7165 12753-12755 IN denotes of
T7166 12756-12761 NN denotes STAT4
T7167 12762-12765 CC denotes and
T7168 12766-12771 NN denotes STAT6
T7169 12772-12781 NN denotes signaling
T7170 12782-12784 IN denotes in
T7171 12785-12788 DT denotes the
T7172 12789-12796 FW denotes in vivo
T7173 12797-12808 NN denotes development
T7174 12809-12811 IN denotes of
T7175 12812-12827 JJ denotes IL-10-producing
T7176 12828-12831 NN denotes Th1
T7177 12832-12837 NN denotes cells
T7178 12837-12838 -COMMA- denotes ,
T7179 12839-12841 PRP denotes we
T7180 12842-12853 VB denotes transferred
T7181 12854-12860 NN denotes STAT4-
T7182 12861-12863 CC denotes or
T7183 12864-12879 JJ denotes STAT6-deficient
T7184 12880-12882 CC denotes or
T7185 12883-12885 JJ denotes WT
T7186 12886-12893 NN denotes DO11.10
T7187 12894-12899 NN denotes cells
T7188 12900-12904 IN denotes into
T7189 12905-12914 JJ denotes recipient
T7190 12915-12921 NN denotes BALB/c
T7191 12922-12926 NN denotes mice
T7192 12927-12930 CC denotes and
T7193 12931-12940 VB denotes immunized
T7194 12941-12945 IN denotes with
T7195 12946-12957 NN denotes OVA-protein
T7196 12958-12962 CC denotes plus
T7197 12963-12966 NN denotes LPS
T7198 12967-12969 IN denotes as
T7199 12970-12976 RB denotes before
T7200 12978-12980 FW denotes In
T7201 12981-12985 FW denotes vivo
T7202 12986-12996 NN denotes expression
T7203 12997-12999 IN denotes of
T7204 13000-13004 CC denotes both
T7205 13005-13010 NN denotes IL-10
T7206 13011-13014 CC denotes and
T7207 13015-13020 NN denotes IFN-γ
T7208 13021-13024 VB denotes was
T7209 13025-13033 RB denotes markedly
T7210 13034-13041 VB denotes reduced
T7211 13042-13045 CC denotes but
T7212 13046-13049 RB denotes not
T7213 13050-13060 RB denotes completely
T7214 13061-13070 VB denotes abrogated
T7215 13071-13073 IN denotes in
T7216 13074-13077 DT denotes the
T7217 13078-13085 NN denotes absence
T7218 13086-13088 IN denotes of
T7219 13089-13094 NN denotes STAT4
T7220 13095-13104 NN denotes signaling
T7221 13105-13106 -LRB- denotes (
T7222 13106-13113 NN denotes Figures
T7223 13114-13116 NN denotes 3B
T7224 13117-13120 CC denotes and
T7225 13121-13123 NN denotes 3C
T7226 13123-13124 -RRB- denotes )
T7227 13124-13125 -COMMA- denotes ,
T7228 13126-13136 VB denotes suggesting
T7229 13137-13140 DT denotes the
T7230 13141-13150 NN denotes existence
T7231 13151-13153 IN denotes of
T7232 13154-13166 JJ denotes compensatory
T7233 13167-13177 NN denotes mechanisms
T7234 13178-13182 WDT denotes that
T7235 13183-13187 VB denotes were
T7236 13188-13194 JJ denotes absent
T7237 13195-13197 IN denotes in
T7238 13198-13201 DT denotes the
T7239 13202-13210 FW denotes in vitro
T7240 13211-13217 NN denotes system
T7241 13219-13228 VB denotes Signaling
T7242 13229-13236 IN denotes through
T7243 13237-13242 NN denotes STAT6
T7244 13243-13246 VB denotes had
T7245 13247-13249 DT denotes no
T7246 13250-13256 NN denotes effect
T7247 13257-13259 IN denotes on
T7248 13260-13265 NN denotes IL-10
T7249 13266-13276 NN denotes production
T7250 13277-13279 IN denotes by
T7251 13280-13283 NN denotes Th1
T7252 13284-13289 NN denotes cells
T7253 13290-13292 IN denotes as
T7254 13293-13298 VB denotes shown
T7255 13299-13301 IN denotes by
T7256 13302-13315 JJ denotes intracellular
T7257 13316-13324 NN denotes cytokine
T7258 13325-13333 NN denotes staining
T7259 13334-13335 -LRB- denotes (
T7260 13335-13338 NN denotes ICS
T7261 13338-13339 -RRB- denotes )
T7262 13340-13343 CC denotes and
T7263 13344-13346 IN denotes by
T7264 13347-13358 NN denotes immunoassay
T7265 13359-13361 IN denotes in
T7266 13362-13377 JJ denotes STAT6-deficient
T7267 13378-13385 NN denotes T cells
T7268 13386-13387 -LRB- denotes (
T7269 13387-13394 NN denotes Figures
T7270 13395-13397 NN denotes 3B
T7271 13398-13401 CC denotes and
T7272 13402-13404 NN denotes 3C
T7273 13404-13405 -RRB- denotes )
T7938 13408-13413 NN denotes IL-10
T7939 13414-13424 NN denotes Production
T7940 13425-13427 VB denotes Is
T7941 13428-13438 VB denotes Maintained
T7942 13439-13441 IN denotes by
T7943 13442-13446 JJ denotes High
T7944 13447-13450 NN denotes TCR
T7945 13451-13457 NN denotes Signal
T7946 13458-13466 NN denotes Strength
T7947 13467-13470 CC denotes and
T7948 13471-13476 NN denotes IL-12
T7949 13477-13479 PRP denotes We
T7950 13480-13484 RB denotes next
T7951 13485-13497 VB denotes investigated
T7952 13498-13505 IN denotes whether
T7953 13506-13514 VB denotes repeated
T7954 13515-13521 JJ denotes strong
T7955 13522-13525 NN denotes TCR
T7956 13526-13536 NN denotes activation
T7957 13537-13539 VB denotes is
T7958 13540-13541 DT denotes a
T7959 13542-13554 JJ denotes compensatory
T7960 13555-13561 NN denotes signal
T7961 13562-13565 IN denotes for
T7962 13566-13579 JJ denotes IL-12-induced
T7963 13580-13585 NN denotes STAT4
T7964 13586-13595 NN denotes signaling
T7965 13596-13598 IN denotes in
T7966 13599-13602 DT denotes the
T7967 13603-13612 NN denotes induction
T7968 13613-13615 IN denotes of
T7969 13616-13621 NN denotes IL-10
T7970 13622-13624 IN denotes in
T7971 13625-13628 NN denotes Th1
T7972 13629-13634 NN denotes cells
T7973 13636-13639 IN denotes For
T7974 13640-13644 DT denotes this
T7975 13644-13645 -COMMA- denotes ,
T7976 13646-13650 JJ denotes CD4+
T7977 13651-13658 NN denotes T cells
T7978 13659-13663 VB denotes were
T7979 13664-13678 VB denotes differentiated
T7980 13679-13682 IN denotes for
T7981 13683-13684 CD denotes 2
T7982 13685-13696 JJ denotes consecutive
T7983 13697-13702 NN denotes weeks
T7984 13703-13707 IN denotes with
T7985 13708-13712 JJ denotes high
T7986 13713-13720 NN denotes antigen
T7987 13721-13726 NN denotes doses
T7988 13727-13729 IN denotes in
T7989 13730-13733 DT denotes the
T7990 13734-13742 NN denotes presence
T7991 13743-13745 CC denotes or
T7992 13746-13753 NN denotes absence
T7993 13754-13756 IN denotes of
T7994 13757-13762 NN denotes IL-12
T7995 13763-13773 IN denotes throughout
T7996 13774-13775 -LRB- denotes (
T7997 13775-13782 NN denotes Figures
T7998 13783-13788 NN denotes 4A–4D
T7999 13788-13789 -RRB- denotes )
T8000 13791-13795 JJ denotes High
T8001 13796-13803 NN denotes antigen
T8002 13804-13808 NN denotes dose
T8003 13809-13812 CC denotes and
T8004 13813-13818 NN denotes IL-12
T8005 13819-13829 VB denotes cooperated
T8006 13830-13832 TO denotes to
T8007 13833-13839 VB denotes induce
T8008 13840-13847 JJ denotes maximal
T8009 13848-13853 NN denotes IL-10
T8010 13854-13864 NN denotes production
T8011 13865-13866 -LRB- denotes (
T8012 13866-13873 NN denotes Figures
T8013 13874-13876 NN denotes 4A
T8014 13877-13880 CC denotes and
T8015 13881-13883 NN denotes 4B
T8016 13883-13884 -RRB- denotes )
T8017 13884-13885 -COMMA- denotes ,
T8018 13886-13891 VB denotes given
T8019 13892-13896 IN denotes that
T8020 13897-13901 DT denotes this
T8021 13902-13913 NN denotes combination
T8022 13914-13922 VB denotes resulted
T8023 13923-13925 IN denotes in
T8024 13926-13929 DT denotes the
T8025 13930-13937 JJ denotes highest
T8026 13938-13945 NN denotes numbers
T8027 13946-13948 IN denotes of
T8028 13949-13964 JJ denotes IL-10-producing
T8029 13965-13968 NN denotes Th1
T8030 13969-13974 NN denotes cells
T8031 13976-13984 VB denotes Repeated
T8032 13985-13989 JJ denotes high
T8033 13990-13997 NN denotes antigen
T8034 13998-14002 NN denotes dose
T8035 14003-14014 NN denotes stimulation
T8036 14015-14017 IN denotes in
T8037 14018-14021 DT denotes the
T8038 14022-14029 NN denotes absence
T8039 14030-14032 IN denotes of
T8040 14033-14044 RB denotes exogenously
T8041 14045-14050 VB denotes added
T8042 14051-14056 NN denotes IL-12
T8043 14057-14065 VB denotes resulted
T8044 14066-14068 IN denotes in
T8045 14069-14072 DT denotes the
T8046 14073-14083 NN denotes production
T8047 14084-14086 IN denotes of
T8048 14087-14092 NN denotes IL-10
T8049 14093-14095 IN denotes by
T8050 14096-14099 NN denotes Th1
T8051 14100-14105 NN denotes cells
T8052 14105-14106 -COMMA- denotes ,
T8053 14107-14117 VB denotes suggesting
T8054 14118-14122 IN denotes that
T8055 14123-14131 VB denotes repeated
T8056 14132-14138 JJ denotes strong
T8057 14139-14142 NN denotes TCR
T8058 14143-14153 NN denotes triggering
T8059 14154-14157 MD denotes may
T8060 14158-14166 VB denotes overcome
T8061 14167-14170 DT denotes the
T8062 14171-14175 NN denotes need
T8063 14176-14179 IN denotes for
T8064 14180-14185 NN denotes IL-12
T8065 14186-14189 IN denotes for
T8066 14190-14195 NN denotes IL-10
T8067 14196-14205 NN denotes induction
T8068 14206-14207 -LRB- denotes (
T8069 14207-14214 NN denotes Figures
T8070 14215-14217 NN denotes 4C
T8071 14218-14221 CC denotes and
T8072 14222-14224 NN denotes 4D
T8073 14224-14225 -RRB- denotes )
T8074 14227-14234 RB denotes However
T8075 14234-14235 -COMMA- denotes ,
T8076 14236-14241 NN denotes IL-10
T8077 14242-14251 NN denotes induction
T8078 14252-14257 IN denotes under
T8079 14258-14263 DT denotes these
T8080 14264-14274 NN denotes conditions
T8081 14275-14278 VB denotes was
T8082 14279-14288 VB denotes abrogated
T8083 14289-14293 WRB denotes when
T8084 14294-14312 JJ denotes IL-12p40-deficient
T8085 14313-14316 NN denotes DCs
T8086 14317-14321 VB denotes were
T8087 14322-14326 VB denotes used
T8088 14327-14329 IN denotes as
T8089 14330-14334 NN denotes APCs
T8090 14335-14336 -LRB- denotes (
T8091 14336-14345 NN denotes Figure 4E
T8092 14345-14346 -RRB- denotes )
T8093 14348-14352 RB denotes Thus
T8094 14352-14353 -COMMA- denotes ,
T8095 14354-14359 NN denotes IL-12
T8096 14360-14362 VB denotes is
T8097 14363-14372 JJ denotes essential
T8098 14373-14379 IN denotes during
T8099 14380-14384 CC denotes both
T8100 14385-14392 JJ denotes primary
T8101 14393-14396 CC denotes and
T8102 14397-14406 JJ denotes secondary
T8103 14407-14416 JJ denotes antigenic
T8104 14417-14428 NN denotes stimulation
T8105 14429-14432 IN denotes for
T8106 14433-14443 NN denotes production
T8107 14444-14446 IN denotes of
T8108 14447-14452 NN denotes IL-10
T8109 14453-14455 IN denotes by
T8110 14456-14459 NN denotes Th1
T8111 14460-14465 NN denotes cells
T8112 14467-14469 TO denotes To
T8113 14470-14479 VB denotes determine
T8114 14480-14483 DT denotes the
T8115 14484-14496 NN denotes requirements
T8116 14497-14500 IN denotes for
T8117 14501-14510 NN denotes stability
T8118 14511-14513 IN denotes of
T8119 14514-14517 DT denotes the
T8120 14518-14533 JJ denotes IL-10-producing
T8121 14534-14537 NN denotes Th1
T8122 14538-14543 NN denotes cells
T8123 14543-14544 -COMMA- denotes ,
T8124 14545-14547 PRP denotes we
T8125 14548-14562 VB denotes differentiated
T8126 14563-14567 JJ denotes CD4+
T8127 14568-14575 NN denotes T cells
T8128 14576-14579 IN denotes for
T8129 14580-14581 CD denotes 1
T8130 14582-14586 NN denotes week
T8131 14587-14591 IN denotes with
T8132 14592-14596 JJ denotes high
T8133 14597-14604 NN denotes antigen
T8134 14605-14610 NN denotes doses
T8135 14611-14615 IN denotes with
T8136 14616-14618 CC denotes or
T8137 14619-14626 IN denotes without
T8138 14627-14632 NN denotes IL-12
T8139 14633-14634 -LRB- denotes (
T8140 14634-14641 NN denotes Figures
T8141 14642-14644 NN denotes 4A
T8142 14645-14648 CC denotes and
T8143 14649-14651 NN denotes 4C
T8144 14651-14652 -RRB- denotes )
T8145 14652-14653 -COMMA- denotes ,
T8146 14654-14660 VB denotes washed
T8147 14661-14665 PRP denotes them
T8148 14665-14666 -COMMA- denotes ,
T8149 14667-14670 CC denotes and
T8150 14671-14675 RB denotes then
T8151 14676-14688 VB denotes restimulated
T8152 14689-14693 PRP denotes them
T8153 14694-14697 IN denotes for
T8154 14698-14700 DT denotes an
T8155 14701-14711 JJ denotes additional
T8156 14712-14716 NN denotes week
T8157 14717-14721 IN denotes with
T8158 14722-14723 DT denotes a
T8159 14724-14727 JJ denotes low
T8160 14728-14735 NN denotes antigen
T8161 14736-14740 NN denotes dose
T8162 14740-14741 -COMMA- denotes ,
T8163 14742-14744 IN denotes in
T8164 14745-14748 DT denotes the
T8165 14749-14756 NN denotes absence
T8166 14757-14759 CC denotes or
T8167 14760-14768 NN denotes presence
T8168 14769-14771 IN denotes of
T8169 14772-14777 NN denotes IL-12
T8170 14778-14779 -LRB- denotes (
T8171 14779-14788 NN denotes Figure 4F
T8172 14788-14789 -RRB- denotes )
T8173 14791-14794 NN denotes Th1
T8174 14795-14800 NN denotes cells
T8175 14801-14808 VB denotes induced
T8176 14809-14811 IN denotes in
T8177 14812-14815 DT denotes the
T8178 14816-14821 JJ denotes first
T8179 14822-14826 NN denotes week
T8180 14827-14829 TO denotes to
T8181 14830-14837 VB denotes produce
T8182 14838-14843 NN denotes IL-10
T8183 14844-14846 IN denotes by
T8184 14847-14854 NN denotes culture
T8185 14855-14859 IN denotes with
T8186 14860-14864 JJ denotes high
T8187 14865-14872 NN denotes antigen
T8188 14873-14878 NN denotes doses
T8189 14879-14882 CC denotes and
T8190 14883-14888 NN denotes IL-12
T8191 14889-14893 VB denotes lost
T8192 14894-14899 PRP-DOLLAR- denotes their
T8193 14900-14907 NN denotes ability
T8194 14908-14910 TO denotes to
T8195 14911-14918 VB denotes express
T8196 14919-14924 NN denotes IL-10
T8197 14925-14929 WRB denotes when
T8198 14930-14940 VB denotes recultured
T8199 14941-14945 IN denotes with
T8200 14946-14949 JJ denotes low
T8201 14950-14955 NN denotes doses
T8202 14956-14958 IN denotes of
T8203 14959-14962 NN denotes OVA
T8204 14962-14963 -COMMA- denotes ,
T8205 14964-14969 WDT denotes which
T8206 14970-14975 MD denotes could
T8207 14976-14978 VB denotes be
T8208 14979-14990 VB denotes compensated
T8209 14991-14994 IN denotes for
T8210 14994-14995 -COMMA- denotes ,
T8211 14996-14998 TO denotes to
T8212 14999-15003 DT denotes some
T8213 15004-15010 NN denotes extent
T8214 15010-15011 -COMMA- denotes ,
T8215 15012-15014 IN denotes by
T8216 15015-15023 NN denotes addition
T8217 15024-15026 IN denotes of
T8218 15027-15032 NN denotes IL-12
T8219 15033-15035 TO denotes to
T8220 15036-15039 DT denotes the
T8221 15040-15049 JJ denotes secondary
T8222 15050-15058 NN denotes cultures
T8223 15059-15060 -LRB- denotes (
T8224 15060-15069 NN denotes Figure 4F
T8225 15069-15070 -RRB- denotes )
T8226 15070-15071 -COMMA- denotes ,
T8227 15072-15077 RB denotes again
T8228 15078-15088 VB denotes suggesting
T8229 15089-15093 IN denotes that
T8230 15094-15101 NN denotes antigen
T8231 15102-15106 NN denotes dose
T8232 15107-15110 CC denotes and
T8233 15111-15116 NN denotes IL-12
T8234 15117-15124 NN denotes signals
T8235 15125-15134 VB denotes cooperate
T8236 15135-15138 IN denotes for
T8237 15139-15142 DT denotes the
T8238 15143-15152 NN denotes induction
T8239 15153-15155 IN denotes of
T8240 15156-15161 NN denotes IL-10
T8241 15163-15170 RB denotes Finally
T8242 15170-15171 -COMMA- denotes ,
T8243 15172-15179 NN denotes DO11.10
T8244 15180-15184 JJ denotes CD4+
T8245 15185-15190 NN denotes cells
T8246 15191-15195 WDT denotes that
T8247 15196-15200 VB denotes were
T8248 15201-15208 VB denotes exposed
T8249 15209-15211 TO denotes to
T8250 15212-15215 JJ denotes low
T8251 15216-15221 NN denotes doses
T8252 15222-15224 IN denotes of
T8253 15225-15232 NN denotes antigen
T8254 15233-15236 CC denotes and
T8255 15237-15242 NN denotes IL-12
T8256 15243-15249 IN denotes during
T8257 15250-15253 DT denotes the
T8258 15254-15261 JJ denotes primary
T8259 15262-15277 NN denotes differentiation
T8260 15278-15283 NN denotes phase
T8261 15284-15292 VB denotes produced
T8262 15293-15297 JJ denotes high
T8263 15298-15305 NN denotes amounts
T8264 15306-15308 IN denotes of
T8265 15309-15314 NN denotes IFN-γ
T8266 15315-15318 CC denotes but
T8267 15319-15325 JJ denotes little
T8268 15326-15331 NN denotes IL-10
T8269 15331-15332 -COMMA- denotes ,
T8270 15333-15336 CC denotes but
T8271 15337-15341 PRP denotes they
T8272 15342-15347 MD denotes could
T8273 15348-15350 VB denotes be
T8274 15351-15358 VB denotes induced
T8275 15359-15361 TO denotes to
T8276 15362-15369 VB denotes produce
T8277 15370-15375 NN denotes IL-10
T8278 15376-15380 WRB denotes when
T8279 15381-15385 CC denotes both
T8280 15386-15390 JJ denotes high
T8281 15391-15398 NN denotes antigen
T8282 15399-15403 NN denotes dose
T8283 15404-15407 CC denotes and
T8284 15408-15413 NN denotes IL-12
T8285 15414-15418 VB denotes were
T8286 15419-15426 JJ denotes present
T8287 15427-15433 IN denotes during
T8288 15434-15437 DT denotes the
T8289 15438-15444 NN denotes recall
T8290 15445-15450 NN denotes phase
T8291 15451-15452 -LRB- denotes (
T8292 15452-15461 NN denotes Figure S4
T8293 15461-15462 -RRB- denotes )
T8294 15464-15468 RB denotes Thus
T8295 15468-15469 -COMMA- denotes ,
T8296 15470-15474 JJ denotes high
T8297 15475-15482 NN denotes antigen
T8298 15483-15487 NN denotes dose
T8299 15488-15491 CC denotes and
T8300 15492-15497 NN denotes IL-12
T8301 15498-15501 VB denotes are
T8302 15502-15510 VB denotes required
T8303 15511-15514 IN denotes for
T8304 15515-15525 VB denotes sustaining
T8305 15526-15529 DT denotes the
T8306 15530-15539 NN denotes induction
T8307 15540-15542 IN denotes of
T8308 15543-15548 NN denotes IL-10
T8309 15549-15559 NN denotes production
T8310 15560-15562 IN denotes by
T8311 15563-15566 NN denotes Th1
T8312 15567-15572 NN denotes cells
T9392 15575-15580 NN denotes IL-10
T9393 15581-15591 NN denotes Production
T9394 15592-15594 IN denotes by
T9395 15595-15598 NN denotes Th1
T9396 15599-15604 NN denotes Cells
T9397 15605-15613 VB denotes Requires
T9398 15614-15618 NN denotes ERK1
T9399 15619-15622 CC denotes and
T9400 15623-15627 NN denotes ERK2
T9401 15628-15638 NN denotes Activation
T9402 15639-15642 PRP-DOLLAR- denotes Our
T9403 15643-15647 NN denotes data
T9404 15648-15654 VB denotes showed
T9405 15655-15659 IN denotes that
T9406 15660-15663 DT denotes the
T9407 15664-15675 NN denotes maintenance
T9408 15676-15678 IN denotes of
T9409 15679-15684 NN denotes IL-10
T9410 15685-15694 NN denotes induction
T9411 15695-15697 IN denotes in
T9412 15698-15701 NN denotes Th1
T9413 15702-15707 NN denotes cells
T9414 15708-15716 VB denotes required
T9415 15717-15728 NN denotes stimulation
T9416 15729-15733 IN denotes with
T9417 15734-15738 JJ denotes high
T9418 15739-15746 NN denotes antigen
T9419 15747-15751 NN denotes dose
T9420 15751-15752 -COMMA- denotes ,
T9421 15753-15758 WDT denotes which
T9422 15759-15761 TO denotes to
T9423 15762-15766 DT denotes some
T9424 15767-15773 NN denotes extent
T9425 15774-15779 MD denotes could
T9426 15780-15782 VB denotes be
T9427 15783-15794 VB denotes compensated
T9428 15795-15798 IN denotes for
T9429 15799-15801 IN denotes by
T9430 15802-15805 DT denotes the
T9431 15806-15814 NN denotes addition
T9432 15815-15817 IN denotes of
T9433 15818-15823 NN denotes IL-12
T9434 15825-15834 VB denotes Signaling
T9435 15835-15842 IN denotes through
T9436 15843-15846 DT denotes the
T9437 15847-15850 NN denotes TCR
T9438 15851-15855 IN denotes with
T9439 15856-15860 JJ denotes high
T9440 15861-15866 NN denotes doses
T9441 15867-15869 IN denotes of
T9442 15870-15877 NN denotes antigen
T9443 15878-15885 VB denotes induced
T9444 15886-15894 JJ denotes stronger
T9445 15895-15899 NN denotes ERK1
T9446 15900-15903 CC denotes and
T9447 15904-15908 NN denotes ERK2
T9448 15909-15919 NN denotes activation
T9449 15920-15924 IN denotes than
T9450 15925-15929 DT denotes that
T9451 15930-15937 VB denotes induced
T9452 15938-15940 IN denotes by
T9453 15941-15944 JJ denotes low
T9454 15945-15952 NN denotes antigen
T9455 15953-15957 NN denotes dose
T9456 15957-15958 -COMMA- denotes ,
T9457 15959-15962 RB denotes not
T9458 15963-15967 RB denotes only
T9459 15968-15970 IN denotes in
T9460 15971-15976 JJ denotes naive
T9461 15977-15981 JJ denotes CD4+
T9462 15982-15989 NN denotes T cells
T9463 15990-15991 -LRB- denotes (
T9464 15991-15995 NN denotes data
T9465 15996-15999 RB denotes not
T9466 16000-16005 VB denotes shown
T9467 16005-16006 -RRB- denotes )
T9468 16007-16009 IN denotes as
T9469 16010-16020 RB denotes previously
T9470 16021-16033 VB denotes demonstrated
T9471 16034-16035 -LRB- denotes (
T9472 16035-16044 NNP denotes Jorritsma
T9473 16045-16051 NNP denotes et al.
T9474 16051-16052 -COMMA- denotes ,
T9475 16053-16057 CD denotes 2003
T9476 16057-16058 -RRB- denotes )
T9477 16059-16062 CC denotes but
T9478 16063-16067 RB denotes also
T9479 16068-16070 IN denotes in
T9480 16071-16075 JJ denotes CD4+
T9481 16076-16083 NN denotes T cells
T9482 16084-16096 VB denotes restimulated
T9483 16097-16101 IN denotes with
T9484 16102-16105 DT denotes the
T9485 16106-16110 JJ denotes same
T9486 16111-16115 JJ denotes high
T9487 16116-16119 CC denotes and
T9488 16120-16123 JJ denotes low
T9489 16124-16131 NN denotes antigen
T9490 16132-16137 NN denotes doses
T9491 16138-16139 -LRB- denotes (
T9492 16139-16148 NN denotes Figure 5A
T9493 16148-16149 -RRB- denotes )
T9494 16151-16159 IN denotes Although
T9495 16160-16163 DT denotes the
T9496 16164-16172 JJ denotes apparent
T9497 16173-16177 NN denotes peak
T9498 16178-16181 CC denotes and
T9499 16182-16188 NN denotes amount
T9500 16189-16191 IN denotes of
T9501 16192-16196 NN denotes ERK1
T9502 16197-16200 CC denotes and
T9503 16201-16205 NN denotes ERK2
T9504 16206-16216 NN denotes activation
T9505 16217-16223 VB denotes varied
T9506 16224-16232 RB denotes slightly
T9507 16233-16240 IN denotes between
T9508 16241-16252 NN denotes experiments
T9509 16252-16253 -COMMA- denotes ,
T9510 16254-16255 DT denotes a
T9511 16256-16266 JJ denotes consistent
T9512 16267-16274 NN denotes finding
T9513 16275-16278 VB denotes was
T9514 16279-16283 IN denotes that
T9515 16284-16288 JJ denotes high
T9516 16289-16296 NN denotes antigen
T9517 16297-16301 NN denotes dose
T9518 16302-16316 VB denotes differentiated
T9519 16317-16320 NN denotes Th1
T9520 16321-16326 NN denotes cells
T9521 16327-16333 RB denotes always
T9522 16334-16340 VB denotes showed
T9523 16341-16349 VB denotes enhanced
T9524 16350-16353 CC denotes and
T9525 16354-16363 JJ denotes prolonged
T9526 16364-16368 NN denotes ERK1
T9527 16369-16372 CC denotes and
T9528 16373-16377 NN denotes ERK2
T9529 16378-16388 NN denotes activation
T9530 16389-16391 IN denotes in
T9531 16392-16395 DT denotes the
T9532 16396-16404 NN denotes presence
T9533 16405-16407 IN denotes of
T9534 16408-16413 NN denotes IL-12
T9535 16413-16414 -COMMA- denotes ,
T9536 16415-16425 RB denotes regardless
T9537 16426-16428 IN denotes of
T9538 16429-16436 IN denotes whether
T9539 16437-16441 PRP denotes they
T9540 16442-16446 VB denotes were
T9541 16447-16459 VB denotes restimulated
T9542 16460-16464 IN denotes with
T9543 16465-16469 JJ denotes high
T9544 16470-16472 CC denotes or
T9545 16473-16476 JJ denotes low
T9546 16477-16484 NN denotes antigen
T9547 16485-16489 NN denotes dose
T9548 16490-16491 -LRB- denotes (
T9549 16491-16500 NN denotes Figure 5B
T9550 16500-16501 -RRB- denotes )
T9551 16503-16505 PRP denotes We
T9552 16506-16510 RB denotes then
T9553 16511-16523 VB denotes investigated
T9554 16524-16531 IN denotes whether
T9555 16532-16536 NN denotes ERK1
T9556 16537-16540 CC denotes and
T9557 16541-16545 NN denotes ERK2
T9558 16546-16556 NN denotes activation
T9559 16557-16560 VB denotes was
T9560 16561-16569 VB denotes required
T9561 16570-16573 IN denotes for
T9562 16574-16577 DT denotes the
T9563 16578-16587 NN denotes induction
T9564 16588-16590 IN denotes of
T9565 16591-16596 NN denotes IL-10
T9566 16597-16599 IN denotes in
T9567 16600-16603 NN denotes Th1
T9568 16604-16609 NN denotes cells
T9569 16610-16612 IN denotes by
T9570 16613-16618 VB denotes using
T9571 16619-16624 NN denotes U0126
T9572 16625-16626 -LRB- denotes (
T9573 16626-16635 NN denotes Figure 5C
T9574 16635-16636 -RRB- denotes )
T9575 16636-16637 -COMMA- denotes ,
T9576 16638-16639 DT denotes a
T9577 16640-16648 NN denotes compound
T9578 16649-16653 WDT denotes that
T9579 16654-16660 VB denotes blocks
T9580 16661-16671 JJ denotes downstream
T9581 16672-16675 NN denotes ERK
T9582 16676-16686 NN denotes activation
T9583 16688-16690 TO denotes To
T9584 16691-16697 VB denotes ensure
T9585 16698-16702 IN denotes that
T9586 16703-16707 RB denotes only
T9587 16708-16714 NN denotes T cell
T9588 16715-16724 NN denotes signaling
T9589 16725-16728 VB denotes was
T9590 16729-16734 VB denotes being
T9591 16735-16743 VB denotes affected
T9592 16744-16746 IN denotes by
T9593 16747-16752 NN denotes U0126
T9594 16752-16753 -COMMA- denotes ,
T9595 16754-16756 PRP denotes we
T9596 16757-16761 VB denotes used
T9597 16762-16764 DT denotes an
T9598 16765-16773 JJ denotes APC-free
T9599 16774-16780 NN denotes system
T9600 16781-16783 IN denotes in
T9601 16784-16789 WDT denotes which
T9602 16790-16793 DT denotes the
T9603 16794-16801 NN denotes T cells
T9604 16802-16806 VB denotes were
T9605 16807-16821 VB denotes differentiated
T9606 16822-16824 IN denotes in
T9607 16825-16828 DT denotes the
T9608 16829-16837 NN denotes presence
T9609 16838-16840 IN denotes of
T9610 16841-16851 VB denotes increasing
T9611 16852-16857 NN denotes doses
T9612 16858-16860 IN denotes of
T9613 16861-16869 NN denotes anti-CD3
T9614 16870-16873 CC denotes and
T9615 16874-16875 DT denotes a
T9616 16876-16884 JJ denotes constant
T9617 16885-16891 NN denotes amount
T9618 16892-16894 IN denotes of
T9619 16895-16900 NN denotes IL-12
T9620 16902-16904 IN denotes As
T9621 16905-16907 IN denotes in
T9622 16908-16911 DT denotes the
T9623 16912-16922 JJ denotes APC-driven
T9624 16923-16931 NN denotes cultures
T9625 16931-16932 -COMMA- denotes ,
T9626 16933-16941 JJ denotes stronger
T9627 16942-16945 NN denotes TCR
T9628 16946-16957 NN denotes stimulation
T9629 16958-16966 RB denotes together
T9630 16967-16971 IN denotes with
T9631 16972-16977 NN denotes IL-12
T9632 16978-16981 VB denotes led
T9633 16982-16984 TO denotes to
T9634 16985-16991 JJ denotes higher
T9635 16992-17003 NN denotes percentages
T9636 17004-17006 IN denotes of
T9637 17007-17012 NN denotes cells
T9638 17013-17022 VB denotes producing
T9639 17023-17027 CC denotes both
T9640 17028-17033 NN denotes IL-10
T9641 17034-17037 CC denotes and
T9642 17038-17043 NN denotes IFN-γ
T9643 17044-17049 IN denotes after
T9644 17050-17051 CD denotes 1
T9645 17052-17056 NN denotes week
T9646 17057-17059 IN denotes of
T9647 17060-17067 NN denotes culture
T9648 17068-17069 -LRB- denotes (
T9649 17069-17078 NN denotes Figure 5C
T9650 17078-17079 -RRB- denotes )
T9651 17081-17089 NN denotes Addition
T9652 17090-17092 IN denotes of
T9653 17093-17098 NN denotes U0126
T9654 17099-17101 TO denotes to
T9655 17102-17105 DT denotes the
T9656 17106-17114 NN denotes cultures
T9657 17115-17124 VB denotes abrogated
T9658 17125-17128 DT denotes the
T9659 17129-17139 NN denotes production
T9660 17140-17142 IN denotes of
T9661 17143-17148 NN denotes IL-10
T9662 17149-17151 IN denotes at
T9663 17152-17155 DT denotes all
T9664 17156-17161 NN denotes doses
T9665 17162-17164 IN denotes of
T9666 17165-17173 NN denotes anti-CD3
T9667 17174-17175 -LRB- denotes (
T9668 17175-17184 NN denotes Figure 5C
T9669 17184-17185 -RRB- denotes )
T9670 17187-17194 IN denotes Because
T9671 17195-17200 NN denotes U0126
T9672 17201-17209 VB denotes inhibits
T9673 17210-17213 DT denotes the
T9674 17214-17228 JJ denotes MEK5-catalyzed
T9675 17229-17239 NN denotes activation
T9676 17240-17242 IN denotes of
T9677 17243-17247 NN denotes ERK5
T9678 17247-17248 -COMMA- denotes ,
T9679 17249-17251 RB denotes as
T9680 17252-17256 RB denotes well
T9681 17257-17259 IN denotes as
T9682 17260-17263 DT denotes the
T9683 17264-17269 NN denotes MEK1-
T9684 17270-17273 CC denotes and
T9685 17274-17288 JJ denotes MEK2-catalyzed
T9686 17289-17299 NN denotes activation
T9687 17300-17302 IN denotes of
T9688 17303-17307 NN denotes ERK1
T9689 17308-17311 CC denotes and
T9690 17312-17316 NN denotes ERK2
T9691 17317-17318 -LRB- denotes (
T9692 17318-17322 NNP denotes Bain
T9693 17323-17329 NNP denotes et al.
T9694 17329-17330 -COMMA- denotes ,
T9695 17331-17335 CD denotes 2007
T9696 17335-17336 -COLON- denotes ;
T9697 17337-17341 NNP denotes Mody
T9698 17342-17348 NNP denotes et al.
T9699 17348-17349 -COMMA- denotes ,
T9700 17350-17354 CD denotes 2001
T9701 17354-17355 -RRB- denotes )
T9702 17355-17356 -COMMA- denotes ,
T9703 17357-17359 PRP denotes we
T9704 17360-17364 RB denotes also
T9705 17365-17369 VB denotes used
T9706 17370-17373 DT denotes the
T9707 17374-17378 RB denotes more
T9708 17379-17387 JJ denotes specific
T9709 17387-17388 -COMMA- denotes ,
T9710 17389-17401 RB denotes structurally
T9711 17402-17411 JJ denotes unrelated
T9712 17412-17416 NN denotes MEK1
T9713 17417-17420 CC denotes and
T9714 17421-17425 NN denotes MEK2
T9715 17426-17435 NN denotes inhibitor
T9716 17436-17444 NN denotes PD184352
T9717 17445-17447 IN denotes at
T9718 17448-17462 NN denotes concentrations
T9719 17463-17465 IN denotes in
T9720 17466-17471 WDT denotes which
T9721 17472-17474 PRP denotes it
T9722 17475-17483 VB denotes inhibits
T9723 17484-17488 NN denotes MEK1
T9724 17489-17492 CC denotes and
T9725 17493-17497 NN denotes MEK2
T9726 17498-17501 CC denotes but
T9727 17502-17505 RB denotes not
T9728 17506-17510 NN denotes MEK5
T9729 17511-17512 -LRB- denotes (
T9730 17512-17516 NNP denotes Bain
T9731 17517-17523 NNP denotes et al.
T9732 17523-17524 -COMMA- denotes ,
T9733 17525-17529 CD denotes 2007
T9734 17529-17530 -COLON- denotes ;
T9735 17531-17535 NNP denotes Mody
T9736 17536-17542 NNP denotes et al.
T9737 17542-17543 -COMMA- denotes ,
T9738 17544-17548 CD denotes 2001
T9739 17548-17549 -RRB- denotes )
T9740 17551-17559 NN denotes PD184352
T9741 17560-17566 VB denotes caused
T9742 17567-17568 DT denotes a
T9743 17569-17576 JJ denotes similar
T9744 17577-17587 NN denotes inhibition
T9745 17588-17590 IN denotes of
T9746 17591-17596 NN denotes IL-10
T9747 17597-17607 NN denotes production
T9748 17608-17610 IN denotes by
T9749 17611-17614 NN denotes Th1
T9750 17615-17620 NN denotes cells
T9751 17621-17623 IN denotes in
T9752 17624-17625 DT denotes a
T9753 17626-17640 JJ denotes dose-dependent
T9754 17641-17648 NN denotes fashion
T9755 17649-17650 -LRB- denotes (
T9756 17650-17659 NN denotes Figure 5D
T9757 17660-17663 CC denotes and
T9758 17664-17674 NN denotes Figure S5A
T9759 17674-17675 -RRB- denotes )
T9760 17677-17681 IN denotes Upon
T9761 17682-17690 NN denotes addition
T9762 17691-17693 IN denotes of
T9763 17694-17704 NN denotes inhibitors
T9764 17705-17707 TO denotes to
T9765 17708-17723 NN denotes other signaling
T9766 17724-17732 NN denotes pathways
T9767 17732-17733 -COMMA- denotes ,
T9768 17734-17743 VB denotes including
T9769 17744-17745 DT denotes a
T9770 17746-17749 NN denotes p38
T9771 17750-17754 NN denotes MAPK
T9772 17755-17764 NN denotes inhibitor
T9773 17764-17765 -COMMA- denotes ,
T9774 17766-17774 NN denotes SB203580
T9775 17774-17775 -COMMA- denotes ,
T9776 17776-17778 CC denotes or
T9777 17779-17782 DT denotes the
T9778 17783-17788 NN denotes GSK3β
T9779 17789-17798 NN denotes inhibitor
T9780 17798-17799 -COMMA- denotes ,
T9781 17800-17807 NN denotes CT99021
T9782 17808-17809 -LRB- denotes (
T9783 17809-17813 NNP denotes Bain
T9784 17814-17820 NNP denotes et al.
T9785 17820-17821 -COMMA- denotes ,
T9786 17822-17826 CD denotes 2007
T9787 17826-17827 -RRB- denotes )
T9788 17827-17828 -COMMA- denotes ,
T9789 17829-17831 DT denotes no
T9790 17832-17838 NN denotes effect
T9791 17839-17841 IN denotes on
T9792 17842-17847 NN denotes IL-10
T9793 17848-17858 NN denotes production
T9794 17859-17862 VB denotes was
T9795 17863-17871 VB denotes observed
T9796 17872-17873 -LRB- denotes (
T9797 17873-17883 NN denotes Figure S5B
T9798 17883-17884 -RRB- denotes )
T9799 17886-17889 PRP-DOLLAR- denotes Our
T9800 17890-17894 NN denotes data
T9801 17895-17899 RB denotes thus
T9802 17900-17909 VB denotes suggested
T9803 17910-17914 IN denotes that
T9804 17915-17920 NN denotes IL-10
T9805 17921-17931 NN denotes production
T9806 17932-17934 IN denotes by
T9807 17935-17938 NN denotes Th1
T9808 17939-17944 NN denotes cells
T9809 17945-17947 IN denotes in
T9810 17948-17956 NN denotes response
T9811 17957-17959 TO denotes to
T9812 17960-17964 JJ denotes high
T9813 17965-17972 NN denotes antigen
T9814 17973-17977 NN denotes dose
T9815 17978-17981 CC denotes and
T9816 17982-17987 NN denotes IL-12
T9817 17988-17996 VB denotes requires
T9818 17997-18001 NN denotes ERK1
T9819 18002-18005 CC denotes and
T9820 18006-18010 NN denotes ERK2
T9821 18011-18020 NN denotes signaling
T9822 18020-18021 -COMMA- denotes ,
T9823 18022-18025 CC denotes but
T9824 18026-18029 RB denotes not
T9825 18030-18033 DT denotes the
T9826 18034-18044 NN denotes activation
T9827 18045-18047 IN denotes of
T9828 18048-18051 DT denotes the
T9829 18052-18055 NN denotes p38
T9830 18056-18058 CC denotes or
T9831 18059-18062 DT denotes the
T9832 18063-18068 NN denotes GSK3β
T9833 18069-18077 NN denotes pathways
T11027 18080-18085 NN denotes IL-10
T11028 18086-18096 NN denotes Production
T11029 18097-18099 IN denotes by
T11030 18100-18103 NN denotes Th2
T11031 18104-18107 CC denotes and
T11032 18108-18112 NN denotes Th17
T11033 18113-18118 NN denotes Cells
T11034 18119-18123 RB denotes Also
T11035 18124-18132 VB denotes Requires
T11036 18133-18137 NN denotes ERK1
T11037 18138-18141 CC denotes and
T11038 18142-18146 NN denotes ERK2
T11039 18147-18157 NN denotes Activation
T11040 18158-18160 TO denotes To
T11041 18161-18168 VB denotes address
T11042 18169-18176 IN denotes whether
T11043 18177-18182 NN denotes IL-10
T11044 18183-18193 NN denotes production
T11045 18194-18196 IN denotes by
T11046 18197-18200 NN denotes Th2
T11047 18201-18204 CC denotes and
T11048 18205-18209 NN denotes Th17
T11049 18210-18215 NN denotes cells
T11050 18216-18219 VB denotes was
T11051 18220-18224 RB denotes also
T11052 18225-18234 JJ denotes dependent
T11053 18235-18237 IN denotes on
T11054 18238-18242 NN denotes ERK1
T11055 18243-18246 CC denotes and
T11056 18247-18251 NN denotes ERK2
T11057 18252-18262 NN denotes activation
T11058 18262-18263 -COMMA- denotes ,
T11059 18264-18266 PRP denotes we
T11060 18267-18281 VB denotes differentiated
T11061 18282-18287 DT denotes these
T11062 18288-18293 NN denotes cells
T11063 18294-18298 IN denotes with
T11064 18299-18307 JJ denotes anti-CD3
T11065 18308-18311 CC denotes and
T11066 18312-18321 JJ denotes anti-CD28
T11067 18322-18324 IN denotes in
T11068 18325-18328 DT denotes the
T11069 18329-18336 NN denotes absence
T11070 18337-18339 IN denotes of
T11071 18340-18344 NN denotes APCs
T11072 18345-18346 -LRB- denotes (
T11073 18346-18355 NN denotes Shoemaker
T11074 18356-18362 NNP denotes et al.
T11075 18362-18363 -COMMA- denotes ,
T11076 18364-18368 CD denotes 2006
T11077 18368-18369 -COLON- denotes ;
T11078 18370-18378 NNP denotes Veldhoen
T11079 18379-18385 FW denotes et al.
T11080 18385-18386 -COMMA- denotes ,
T11081 18387-18391 CD denotes 2009
T11082 18391-18392 -COLON- denotes ;
T11083 18393-18401 NNP denotes Veldhoen
T11084 18402-18408 FW denotes et al.
T11085 18408-18409 -COMMA- denotes ,
T11086 18410-18414 CD denotes 2006
T11087 18414-18415 -RRB- denotes )
T11088 18415-18416 -COMMA- denotes ,
T11089 18417-18419 IN denotes in
T11090 18420-18423 DT denotes the
T11091 18424-18432 NN denotes presence
T11092 18433-18435 CC denotes or
T11093 18436-18443 NN denotes absence
T11094 18444-18446 IN denotes of
T11095 18447-18450 DT denotes the
T11096 18451-18454 NN denotes MEK
T11097 18455-18464 NN denotes inhibitor
T11098 18465-18466 -LRB- denotes (
T11099 18466-18474 NN denotes PD184352
T11100 18474-18475 -RRB- denotes )
T11101 18477-18479 PRP denotes We
T11102 18480-18486 VB denotes showed
T11103 18487-18491 IN denotes that
T11104 18492-18496 NN denotes ERK1
T11105 18497-18500 CC denotes and
T11106 18501-18505 NN denotes ERK2
T11107 18506-18516 NN denotes activation
T11108 18517-18519 VB denotes is
T11109 18520-18521 DT denotes a
T11110 18522-18528 JJ denotes common
T11111 18529-18536 NN denotes pathway
T11112 18537-18545 VB denotes required
T11113 18546-18549 IN denotes for
T11114 18550-18559 NN denotes induction
T11115 18560-18562 IN denotes of
T11116 18563-18568 NN denotes IL-10
T11117 18569-18571 IN denotes in
T11118 18572-18581 JJ denotes different
T11119 18582-18584 NN denotes Th
T11120 18585-18589 NN denotes cell
T11121 18590-18597 NN denotes subsets
T11122 18598-18605 IN denotes because
T11123 18606-18611 NN denotes IL-10
T11124 18612-18622 NN denotes production
T11125 18623-18625 IN denotes by
T11126 18626-18630 CC denotes both
T11127 18631-18634 NN denotes Th2
T11128 18635-18638 CC denotes and
T11129 18639-18643 NN denotes Th17
T11130 18644-18649 NN denotes cells
T11131 18650-18653 VB denotes was
T11132 18654-18662 RB denotes markedly
T11133 18663-18672 VB denotes inhibited
T11134 18673-18675 IN denotes in
T11135 18676-18679 DT denotes the
T11136 18680-18688 NN denotes presence
T11137 18689-18691 IN denotes of
T11138 18692-18695 DT denotes the
T11139 18696-18699 NN denotes MEK
T11140 18700-18709 NN denotes inhibitor
T11141 18710-18711 -LRB- denotes (
T11142 18711-18719 NN denotes PD184352
T11143 18719-18720 -RRB- denotes )
T11144 18721-18722 -LRB- denotes (
T11145 18722-18731 NN denotes Figure 5D
T11146 18732-18735 CC denotes and
T11147 18736-18746 NN denotes Figure S5B
T11148 18746-18747 -RRB- denotes )
T11149 18749-18751 IN denotes In
T11150 18752-18760 NN denotes contrast
T11151 18760-18761 -COMMA- denotes ,
T11152 18762-18772 NN denotes inhibitors
T11153 18773-18775 IN denotes of
T11154 18776-18779 NN denotes p38
T11155 18780-18784 NN denotes MAPK
T11156 18785-18787 CC denotes or
T11157 18788-18790 IN denotes of
T11158 18791-18797 NN denotes GSK-3β
T11159 18798-18808 NN denotes activation
T11160 18809-18812 VB denotes did
T11161 18813-18816 RB denotes not
T11162 18817-18823 VB denotes affect
T11163 18824-18827 DT denotes the
T11164 18828-18838 NN denotes expression
T11165 18839-18841 IN denotes of
T11166 18842-18847 NN denotes IL-10
T11167 18848-18850 IN denotes by
T11168 18851-18856 DT denotes these
T11169 18857-18864 NN denotes subsets
T11170 18865-18866 -LRB- denotes (
T11171 18866-18876 NN denotes Figure S5B
T11172 18876-18877 -RRB- denotes )
T11173 18879-18889 NN denotes Activation
T11174 18890-18892 IN denotes of
T11175 18893-18896 DT denotes the
T11176 18897-18901 NN denotes ERK1
T11177 18902-18905 CC denotes and
T11178 18906-18910 NN denotes ERK2
T11179 18911-18920 NN denotes signaling
T11180 18921-18928 NN denotes pathway
T11181 18929-18931 VB denotes is
T11182 18932-18941 RB denotes therefore
T11183 18942-18943 DT denotes a
T11184 18944-18950 JJ denotes common
T11185 18951-18962 NN denotes requirement
T11186 18963-18966 IN denotes for
T11187 18967-18970 DT denotes the
T11188 18971-18980 NN denotes induction
T11189 18981-18983 IN denotes of
T11190 18984-18989 NN denotes IL-10
T11191 18990-19000 NN denotes production
T11192 19001-19003 IN denotes by
T11193 19004-19007 NN denotes Th1
T11194 19007-19008 -COMMA- denotes ,
T11195 19009-19012 NN denotes Th2
T11196 19012-19013 -COMMA- denotes ,
T11197 19014-19017 CC denotes and
T11198 19018-19022 NN denotes Th17
T11199 19023-19028 NN denotes cells
T11958 19031-19036 NN denotes c-maf
T11959 19037-19047 NN denotes Expression
T11960 19048-19058 VB denotes Correlates
T11961 19059-19063 IN denotes with
T11962 19064-19069 NN denotes IL-10
T11963 19070-19080 NN denotes Production
T11964 19081-19083 IN denotes in
T11965 19084-19087 NN denotes Th1
T11966 19087-19088 -COMMA- denotes ,
T11967 19089-19092 NN denotes Th2
T11968 19092-19093 -COMMA- denotes ,
T11969 19094-19097 CC denotes and
T11970 19098-19102 NN denotes Th17
T11971 19103-19108 NN denotes Cells
T11972 19109-19111 TO denotes To
T11973 19112-19123 VB denotes investigate
T11974 19124-19131 RB denotes further
T11975 19132-19135 DT denotes the
T11976 19136-19146 JJ denotes downstream
T11977 19147-19154 NN denotes factors
T11978 19155-19163 VB denotes involved
T11979 19164-19166 IN denotes in
T11980 19167-19177 VB denotes regulating
T11981 19178-19183 NN denotes IL-10
T11982 19184-19194 NN denotes production
T11983 19194-19195 -COMMA- denotes ,
T11984 19196-19198 PRP denotes we
T11985 19199-19213 VB denotes differentiated
T11986 19214-19221 NN denotes DO11.10
T11987 19222-19226 JJ denotes CD4+
T11988 19227-19234 NN denotes T cells
T11989 19235-19239 IN denotes with
T11990 19240-19250 VB denotes increasing
T11991 19251-19256 NN denotes doses
T11992 19257-19259 IN denotes of
T11993 19260-19263 NN denotes OVA
T11994 19263-19264 -COMMA- denotes ,
T11995 19265-19267 IN denotes in
T11996 19268-19271 DT denotes the
T11997 19272-19280 NN denotes presence
T11998 19281-19283 CC denotes or
T11999 19284-19291 NN denotes absence
T12000 19292-19294 IN denotes of
T12001 19295-19300 NN denotes IL-12
T12002 19300-19301 -COMMA- denotes ,
T12003 19302-19305 CC denotes and
T12004 19306-19316 VB denotes quantified
T12005 19317-19320 DT denotes the
T12006 19321-19331 NN denotes expression
T12007 19332-19334 IN denotes of
T12008 19335-19344 NN denotes cytokines
T12009 19345-19348 CC denotes and
T12010 19349-19362 NN denotes transcription
T12011 19363-19370 NN denotes factors
T12012 19371-19373 IN denotes by
T12013 19374-19383 JJ denotes real-time
T12014 19384-19390 NN denotes RT-PCR
T12015 19392-19400 JJ denotes Low-dose
T12016 19401-19408 NN denotes antigen
T12017 19409-19417 VB denotes resulted
T12018 19418-19420 IN denotes in
T12019 19421-19434 NN denotes transcription
T12020 19435-19437 IN denotes of
T12021 19438-19441 NN denotes Il4
T12022 19442-19445 CC denotes and
T12023 19446-19450 DT denotes this
T12024 19451-19454 VB denotes was
T12025 19455-19464 VB denotes abrogated
T12026 19465-19467 IN denotes by
T12027 19468-19472 CC denotes both
T12028 19473-19477 JJ denotes high
T12029 19478-19485 NN denotes antigen
T12030 19486-19491 NN denotes doses
T12031 19492-19495 CC denotes and
T12032 19496-19501 NN denotes IL-12
T12033 19502-19503 -LRB- denotes (
T12034 19503-19512 NN denotes Figure 6A
T12035 19512-19513 -RRB- denotes )
T12036 19515-19516 DT denotes A
T12037 19517-19520 JJ denotes low
T12038 19521-19527 NN denotes amount
T12039 19528-19530 IN denotes of
T12040 19531-19544 NN denotes transcription
T12041 19545-19547 IN denotes of
T12042 19548-19552 NN denotes Ifnγ
T12043 19553-19556 VB denotes was
T12044 19557-19564 VB denotes induced
T12045 19565-19567 IN denotes by
T12046 19568-19573 NN denotes IL-12
T12047 19574-19578 WRB denotes when
T12048 19579-19584 NN denotes cells
T12049 19585-19589 VB denotes were
T12050 19590-19604 VB denotes differentiated
T12051 19605-19609 IN denotes with
T12052 19610-19613 JJ denotes low
T12053 19614-19621 NN denotes antigen
T12054 19622-19626 NN denotes dose
T12055 19626-19627 -COMMA- denotes ,
T12056 19628-19631 CC denotes but
T12057 19632-19636 DT denotes this
T12058 19637-19643 NN denotes effect
T12059 19644-19646 IN denotes of
T12060 19647-19652 NN denotes IL-12
T12061 19653-19656 VB denotes was
T12062 19657-19665 RB denotes markedly
T12063 19666-19677 VB denotes upregulated
T12064 19678-19682 IN denotes with
T12065 19683-19693 VB denotes increasing
T12066 19694-19699 NN denotes doses
T12067 19700-19702 IN denotes of
T12068 19703-19710 NN denotes antigen
T12069 19711-19712 -LRB- denotes (
T12070 19712-19721 NN denotes Figure 6A
T12071 19721-19722 -RRB- denotes )
T12072 19724-19725 DT denotes A
T12073 19726-19729 JJ denotes low
T12074 19730-19736 NN denotes amount
T12075 19737-19739 IN denotes of
T12076 19740-19744 NN denotes Il10
T12077 19745-19758 NN denotes transcription
T12078 19759-19762 VB denotes was
T12079 19763-19771 VB denotes observed
T12080 19772-19774 IN denotes at
T12081 19775-19778 JJ denotes low
T12082 19779-19784 NN denotes doses
T12083 19785-19787 IN denotes of
T12084 19788-19795 NN denotes antigen
T12085 19796-19808 VB denotes accompanying
T12086 19809-19812 NN denotes Il4
T12087 19813-19823 NN denotes expression
T12088 19824-19825 -LRB- denotes (
T12089 19825-19828 NN denotes Th2
T12090 19829-19833 NN denotes cell
T12091 19834-19842 NN denotes response
T12092 19842-19843 -RRB- denotes )
T12093 19843-19844 -COMMA- denotes ,
T12094 19845-19848 CC denotes and
T12095 19849-19853 DT denotes this
T12096 19854-19857 VB denotes was
T12097 19858-19867 VB denotes abrogated
T12098 19868-19870 IN denotes by
T12099 19871-19880 VB denotes increased
T12100 19881-19886 NN denotes doses
T12101 19887-19889 IN denotes of
T12102 19890-19897 NN denotes antigen
T12103 19898-19900 IN denotes as
T12104 19901-19904 VB denotes was
T12105 19905-19908 NN denotes Il4
T12106 19909-19919 NN denotes expression
T12107 19920-19921 -LRB- denotes (
T12108 19921-19930 NN denotes Figure 6A
T12109 19930-19931 -RRB- denotes )
T12110 19933-19935 IN denotes At
T12111 19936-19939 JJ denotes low
T12112 19940-19945 NN denotes doses
T12113 19946-19948 IN denotes of
T12114 19949-19956 NN denotes antigen
T12115 19956-19957 -COMMA- denotes ,
T12116 19958-19963 NN denotes IL-12
T12117 19964-19967 VB denotes had
T12118 19968-19974 JJ denotes little
T12119 19975-19981 NN denotes effect
T12120 19982-19984 TO denotes to
T12121 19985-19993 VB denotes increase
T12122 19994-19999 NN denotes IL-10
T12123 20000-20004 NN denotes mRNA
T12124 20005-20015 NN denotes expression
T12125 20016-20017 -LRB- denotes (
T12126 20017-20026 NN denotes Figure 6A
T12127 20026-20027 -RRB- denotes )
T12128 20028-20030 IN denotes in
T12129 20031-20038 VB denotes keeping
T12130 20039-20043 IN denotes with
T12131 20044-20047 DT denotes the
T12132 20048-20055 NN denotes protein
T12133 20056-20060 NN denotes data
T12134 20061-20062 -LRB- denotes (
T12135 20062-20071 NN denotes Figure 1A
T12136 20071-20072 -RRB- denotes )
T12137 20074-20081 RB denotes However
T12138 20081-20082 -COMMA- denotes ,
T12139 20083-20088 NN denotes IL-12
T12140 20089-20096 VB denotes induced
T12141 20097-20098 DT denotes a
T12142 20099-20103 JJ denotes high
T12143 20104-20110 NN denotes amount
T12144 20111-20113 IN denotes of
T12145 20114-20118 NN denotes Il10
T12146 20119-20132 NN denotes transcription
T12147 20133-20135 RB denotes as
T12148 20136-20140 RB denotes well
T12149 20141-20143 IN denotes as
T12150 20144-20148 NN denotes Ifnγ
T12151 20149-20159 NN denotes expression
T12152 20160-20164 IN denotes with
T12153 20165-20174 VB denotes increased
T12154 20175-20182 NN denotes antigen
T12155 20183-20188 NN denotes doses
T12156 20189-20190 -LRB- denotes (
T12157 20190-20199 NN denotes Figure 6A
T12158 20199-20200 -RRB- denotes )
T12159 20200-20201 -COMMA- denotes ,
T12160 20202-20207 RB denotes again
T12161 20208-20210 IN denotes in
T12162 20211-20218 VB denotes keeping
T12163 20219-20223 IN denotes with
T12164 20224-20227 DT denotes the
T12165 20228-20235 NN denotes protein
T12166 20236-20240 NN denotes data
T12167 20241-20242 -LRB- denotes (
T12168 20242-20251 NN denotes Figure 1A
T12169 20251-20252 -RRB- denotes )
T12170 20254-20258 JJ denotes CD4+
T12171 20259-20266 NN denotes T cells
T12172 20267-20281 VB denotes differentiated
T12173 20282-20286 IN denotes with
T12174 20287-20297 VB denotes increasing
T12175 20298-20303 NN denotes doses
T12176 20304-20306 IN denotes of
T12177 20307-20314 NN denotes antigen
T12178 20315-20318 VB denotes did
T12179 20319-20322 RB denotes not
T12180 20323-20330 VB denotes express
T12181 20331-20335 JJ denotes high
T12182 20336-20343 NN denotes amounts
T12183 20344-20346 IN denotes of
T12184 20347-20353 NN denotes Tbx-21
T12185 20354-20355 -LRB- denotes (
T12186 20355-20360 NN denotes T-bet
T12187 20360-20361 -RRB- denotes )
T12188 20362-20366 NN denotes mRNA
T12189 20366-20367 -COMMA- denotes ,
T12190 20368-20374 IN denotes unless
T12191 20375-20379 PRP denotes they
T12192 20380-20384 VB denotes were
T12193 20385-20395 VB denotes cocultured
T12194 20396-20400 IN denotes with
T12195 20401-20406 NN denotes IL-12
T12196 20407-20408 -LRB- denotes (
T12197 20408-20417 NN denotes Figure 6B
T12198 20417-20418 -RRB- denotes )
T12199 20420-20422 IN denotes In
T12200 20423-20431 NN denotes contrast
T12201 20431-20432 -COMMA- denotes ,
T12202 20433-20437 JJ denotes high
T12203 20438-20445 NN denotes amounts
T12204 20446-20448 IN denotes of
T12205 20449-20455 NN denotes GATA-3
T12206 20456-20460 NN denotes mRNA
T12207 20461-20471 NN denotes expression
T12208 20472-20476 VB denotes were
T12209 20477-20481 RB denotes only
T12210 20482-20490 VB denotes observed
T12211 20491-20496 IN denotes under
T12212 20497-20500 NN denotes Th2
T12213 20501-20505 NN denotes cell
T12214 20506-20521 NN denotes differentiation
T12215 20522-20532 NN denotes conditions
T12216 20533-20534 -LRB- denotes (
T12217 20534-20542 JJ denotes low-dose
T12218 20543-20550 NN denotes antigen
T12219 20550-20551 -RRB- denotes )
T12220 20552-20553 -LRB- denotes (
T12221 20553-20562 NN denotes Figure 6B
T12222 20562-20563 -RRB- denotes )
T12223 20563-20564 -COMMA- denotes ,
T12224 20565-20568 CC denotes and
T12225 20569-20573 DT denotes this
T12226 20574-20584 NN denotes expression
T12227 20585-20588 VB denotes was
T12228 20589-20597 RB denotes markedly
T12229 20598-20611 VB denotes downregulated
T12230 20612-20614 IN denotes by
T12231 20615-20619 CC denotes both
T12232 20620-20630 VB denotes increasing
T12233 20631-20638 NN denotes antigen
T12234 20639-20643 NN denotes dose
T12235 20644-20647 CC denotes and
T12236 20648-20657 NN denotes coculture
T12237 20658-20660 IN denotes in
T12238 20661-20666 NN denotes IL-12
T12239 20667-20668 -LRB- denotes (
T12240 20668-20677 NN denotes Figure 6B
T12241 20677-20678 -RRB- denotes )
T12242 20680-20695 NN denotes Differentiation
T12243 20696-20698 IN denotes of
T12244 20699-20706 NN denotes T cells
T12245 20707-20712 IN denotes under
T12246 20713-20716 JJ denotes low
T12247 20717-20724 NN denotes antigen
T12248 20725-20729 NN denotes dose
T12249 20730-20733 VB denotes led
T12250 20734-20736 TO denotes to
T12251 20737-20747 NN denotes expression
T12252 20748-20750 IN denotes of
T12253 20751-20756 NN denotes c-maf
T12254 20756-20757 -COMMA- denotes ,
T12255 20758-20760 IN denotes in
T12256 20761-20768 VB denotes keeping
T12257 20769-20773 IN denotes with
T12258 20774-20777 DT denotes the
T12259 20778-20781 NN denotes Th2
T12260 20782-20786 NN denotes cell
T12261 20787-20794 NN denotes profile
T12262 20795-20796 -LRB- denotes (
T12263 20796-20798 NNP denotes Ho
T12264 20799-20805 NNP denotes et al.
T12265 20805-20806 -COMMA- denotes ,
T12266 20807-20811 CD denotes 1996
T12267 20811-20812 -RRB- denotes )
T12268 20812-20813 -COMMA- denotes ,
T12269 20814-20819 WDT denotes which
T12270 20820-20823 VB denotes was
T12271 20824-20830 RB denotes almost
T12272 20831-20841 RB denotes completely
T12273 20842-20851 VB denotes abrogated
T12274 20852-20854 IN denotes by
T12275 20855-20865 VB denotes increasing
T12276 20866-20871 NN denotes doses
T12277 20872-20874 IN denotes of
T12278 20875-20882 NN denotes antigen
T12279 20883-20884 -LRB- denotes (
T12280 20884-20893 NN denotes Figure 6B
T12281 20893-20894 -RRB- denotes )
T12282 20896-20909 RB denotes Interestingly
T12283 20909-20910 -COMMA- denotes ,
T12284 20911-20916 NN denotes IL-12
T12285 20917-20926 VB denotes sustained
T12286 20927-20930 DT denotes the
T12287 20931-20935 JJ denotes high
T12288 20936-20946 NN denotes expression
T12289 20947-20949 IN denotes of
T12290 20950-20955 NN denotes c-Maf
T12291 20956-20960 NN denotes mRNA
T12292 20961-20965 RB denotes even
T12293 20966-20968 IN denotes at
T12294 20969-20972 DT denotes the
T12295 20973-20980 JJ denotes highest
T12296 20981-20988 NN denotes antigen
T12297 20989-20993 NN denotes dose
T12298 20994-20995 -LRB- denotes (
T12299 20995-21004 NN denotes Figure 6B
T12300 21004-21005 -RRB- denotes )
T12301 21007-21015 RB denotes Moreover
T12302 21015-21016 -COMMA- denotes ,
T12303 21017-21022 NN denotes IL-12
T12304 21023-21034 NN denotes maintenance
T12305 21035-21037 IN denotes of
T12306 21038-21043 NN denotes c-maf
T12307 21044-21054 NN denotes expression
T12308 21055-21063 VB denotes required
T12309 21064-21069 NN denotes STAT4
T12310 21070-21080 NN denotes activation
T12311 21081-21082 -LRB- denotes (
T12312 21082-21086 NN denotes data
T12313 21087-21090 RB denotes not
T12314 21091-21096 VB denotes shown
T12315 21096-21097 -RRB- denotes )
T12316 21099-21101 IN denotes In
T12317 21102-21106 NN denotes Th17
T12318 21107-21112 NN denotes cells
T12319 21113-21117 WDT denotes that
T12320 21118-21127 VB denotes expressed
T12321 21128-21134 NN denotes IL-17a
T12322 21135-21137 RB denotes as
T12323 21138-21142 RB denotes well
T12324 21143-21145 IN denotes as
T12325 21146-21151 NN denotes IL-10
T12326 21152-21156 NN denotes mRNA
T12327 21157-21158 -LRB- denotes (
T12328 21158-21167 NN denotes Figure 6C
T12329 21167-21168 -RRB- denotes )
T12330 21168-21169 -COMMA- denotes ,
T12331 21170-21175 NN denotes T-bet
T12332 21176-21179 CC denotes and
T12333 21180-21186 NN denotes GATA-3
T12334 21187-21191 NN denotes mRNA
T12335 21192-21196 VB denotes were
T12336 21197-21209 JJ denotes undetectable
T12337 21210-21211 -LRB- denotes (
T12338 21211-21215 NN denotes data
T12339 21216-21219 RB denotes not
T12340 21220-21225 VB denotes shown
T12341 21225-21226 -RRB- denotes )
T12342 21226-21227 -COMMA- denotes ,
T12343 21228-21235 IN denotes whereas
T12344 21236-21240 DT denotes that
T12345 21241-21243 IN denotes of
T12346 21244-21250 NN denotes ROR-γt
T12347 21251-21254 VB denotes was
T12348 21255-21259 JJ denotes high
T12349 21260-21261 -LRB- denotes (
T12350 21261-21270 NN denotes Figure 6C
T12351 21270-21271 -RRB- denotes )
T12352 21272-21273 -LRB- denotes (
T12353 21273-21279 NNP denotes Ivanov
T12354 21280-21286 NNP denotes et al.
T12355 21286-21287 -COMMA- denotes ,
T12356 21288-21292 CD denotes 2007
T12357 21292-21293 -RRB- denotes )
T12358 21295-21299 NN denotes Th17
T12359 21300-21305 NN denotes cells
T12360 21306-21310 RB denotes also
T12361 21311-21320 VB denotes expressed
T12362 21321-21325 JJ denotes high
T12363 21326-21333 NN denotes amounts
T12364 21334-21336 IN denotes of
T12365 21337-21342 NN denotes c-maf
T12366 21343-21344 -LRB- denotes (
T12367 21344-21353 NN denotes Figure 6C
T12368 21353-21354 -RRB- denotes )
T12369 21354-21355 -COMMA- denotes ,
T12370 21356-21366 VB denotes confirming
T12371 21367-21368 DT denotes a
T12372 21369-21375 JJ denotes recent
T12373 21376-21382 NN denotes report
T12374 21383-21384 -LRB- denotes (
T12375 21384-21391 NNP denotes Bauquet
T12376 21392-21398 NNP denotes et al.
T12377 21398-21399 -COMMA- denotes ,
T12378 21400-21404 CD denotes 2009
T12379 21404-21405 -RRB- denotes )
T12380 21405-21410 NN denotes . c-M
T12381 21410-21412 VB denotes af
T12382 21413-21422 RB denotes is theref
T12383 21422-21431 VB denotes ore expre
T12384 21431-21433 IN denotes ss
T12385 21433-21436 DT denotes ed
T12386 21436-21452 JJ denotes in all IL-10-exp
T12387 21452-21458 NN denotes ressin
T12388 21458-21469 NN denotes g T cell po
T12389 21469-21475 VB denotes pulati
T12390 21475-21476 -LRB- denotes o
T12391 21476-21483 NN denotes ns test
T12392 21483-21485 NN denotes ed
T12393 21486-21489 CC denotes (Fi
T12394 21489-21491 NN denotes gu
T12395 21491-21492 -RRB- denotes r
T12396 21492-21495 CC denotes es
T12397 21495-21498 MD denotes 6B
T12398 21498-21501 RB denotes and
T12399 21502-21504 VB denotes 6C
T12400 21504-21508 RB denotes ) an
T12401 21508-21509 DT denotes d
T12402 21510-21513 NN denotes may
T12403 21514-21527 JJ denotes not be just a
T12404 21528-21541 NN denotes Th2 cell-spec
T12405 21541-21547 NN denotes ific t
T12406 21547-21549 IN denotes ra
T12407 21549-21559 RB denotes nscription
T12408 21560-21567 VB denotes factor
T12409 21567-21568 -LRB- denotes a
T12410 21568-21570 NNP denotes s
T12411 21570-21576 NNP denotes origin
T12412 21576-21577 -COMMA- denotes a
T12413 21577-21581 CD denotes lly
T12414 21581-21582 -RRB- denotes t
T12415 21608-21610 PRP denotes We
T12416 21611-21617 VB denotes showed
T12417 21618-21622 RB denotes also
T12418 21623-21627 IN denotes that
T12419 21628-21632 IN denotes like
T12420 21633-21637 NN denotes Il10
T12421 21638-21648 NN denotes expression
T12422 21648-21649 -COMMA- denotes ,
T12423 21650-21655 NN denotes c-maf
T12424 21656-21666 NN denotes expression
T12425 21667-21670 VB denotes was
T12426 21671-21680 VB denotes inhibited
T12427 21681-21683 IN denotes in
T12428 21684-21687 NN denotes Th1
T12429 21688-21691 CC denotes and
T12430 21692-21696 NN denotes Th17
T12431 21697-21702 NN denotes cells
T12432 21703-21705 IN denotes in
T12433 21706-21709 DT denotes the
T12434 21710-21718 NN denotes presence
T12435 21719-21721 IN denotes of
T12436 21722-21725 DT denotes the
T12437 21726-21730 NN denotes MEK1
T12438 21731-21734 CC denotes and
T12439 21735-21739 NN denotes MEK2
T12440 21740-21749 NN denotes inhibitor
T12441 21750-21751 -LRB- denotes (
T12442 21751-21759 NN denotes PD184352
T12443 21759-21760 -RRB- denotes )
T12444 21760-21761 -COMMA- denotes ,
T12445 21762-21769 IN denotes whereas
T12446 21770-21775 NN denotes T-bet
T12447 21776-21779 CC denotes and
T12448 21780-21785 NN denotes RORγt
T12449 21786-21796 NN denotes expression
T12450 21797-21800 VB denotes was
T12451 21801-21807 RB denotes hardly
T12452 21808-21816 VB denotes affected
T12453 21817-21818 -LRB- denotes (
T12454 21818-21827 NN denotes Figure 6D
T12455 21827-21828 -RRB- denotes )
T14233 21842-21847 NN denotes IL-10
T14234 21848-21858 NN denotes expression
T14235 21859-21861 IN denotes by
T14236 21862-21867 NN denotes cells
T14237 21868-21870 IN denotes of
T14238 21871-21874 DT denotes the
T14239 21875-21881 JJ denotes innate
T14240 21882-21885 CC denotes and
T14241 21886-21894 JJ denotes adaptive
T14242 21895-21901 JJ denotes immune
T14243 21902-21909 NN denotes systems
T14244 21910-21918 VB denotes reflects
T14245 21919-21922 DT denotes the
T14246 21923-21933 NN denotes importance
T14247 21934-21936 IN denotes of
T14248 21937-21941 DT denotes this
T14249 21942-21950 NN denotes cytokine
T14250 21951-21953 IN denotes in
T14251 21954-21957 DT denotes the
T14252 21958-21963 JJ denotes tight
T14253 21964-21974 NN denotes regulation
T14254 21975-21977 IN denotes of
T14255 21978-21981 DT denotes the
T14256 21982-21988 JJ denotes immune
T14257 21989-21997 NN denotes response
T14258 21997-21998 -COMMA- denotes ,
T14259 21999-22001 TO denotes to
T14260 22002-22010 VB denotes minimize
T14261 22011-22020 NN denotes pathology
T14262 22021-22027 IN denotes during
T14263 22028-22037 NN denotes infection
T14264 22039-22044 NN denotes IL-10
T14265 22045-22055 NN denotes expression
T14266 22056-22058 IN denotes by
T14267 22059-22062 NN denotes Th1
T14268 22063-22068 NN denotes cells
T14269 22069-22072 VB denotes has
T14270 22073-22077 VB denotes been
T14271 22078-22086 VB denotes reported
T14272 22087-22089 TO denotes to
T14273 22090-22098 VB denotes regulate
T14274 22099-22102 DT denotes the
T14275 22103-22109 JJ denotes immune
T14276 22110-22118 NN denotes response
T14277 22119-22121 IN denotes in
T14278 22122-22135 NN denotes leishmaniasis
T14279 22136-22139 CC denotes and
T14280 22140-22153 NN denotes toxoplasmosis
T14281 22155-22162 RB denotes However
T14282 22162-22163 -COMMA- denotes ,
T14283 22164-22166 IN denotes in
T14284 22167-22171 JJ denotes many
T14285 22172-22182 NN denotes situations
T14286 22182-22183 -COMMA- denotes ,
T14287 22184-22189 NN denotes IL-10
T14288 22190-22192 VB denotes is
T14289 22193-22196 RB denotes not
T14290 22197-22205 VB denotes produced
T14291 22206-22208 IN denotes by
T14292 22209-22212 NN denotes Th1
T14293 22213-22218 NN denotes cells
T14294 22219-22221 IN denotes in
T14295 22222-22230 NN denotes response
T14296 22231-22233 TO denotes to
T14297 22234-22243 JJ denotes antigenic
T14298 22244-22255 NN denotes stimulation
T14299 22257-22260 PRP-DOLLAR- denotes Our
T14300 22261-22265 NN denotes goal
T14301 22266-22269 VB denotes was
T14302 22270-22272 TO denotes to
T14303 22273-22280 VB denotes address
T14304 22281-22284 DT denotes the
T14305 22285-22294 JJ denotes molecular
T14306 22295-22302 NN denotes signals
T14307 22303-22307 WDT denotes that
T14308 22308-22317 VB denotes determine
T14309 22318-22325 IN denotes whether
T14310 22326-22329 NN denotes Th1
T14311 22330-22335 NN denotes cells
T14312 22336-22343 VB denotes develop
T14313 22344-22346 TO denotes to
T14314 22347-22354 VB denotes produce
T14315 22355-22360 NN denotes IL-10
T14316 22361-22362 -LRB- denotes (
T14317 22362-22372 NNP denotes Trinchieri
T14318 22372-22373 -COMMA- denotes ,
T14319 22374-22378 CD denotes 2007
T14320 22378-22379 -RRB- denotes )
T14321 22381-22385 RB denotes Here
T14322 22385-22386 -COMMA- denotes ,
T14323 22387-22389 PRP denotes we
T14324 22390-22396 VB denotes showed
T14325 22397-22401 IN denotes that
T14326 22402-22405 NN denotes Th1
T14327 22406-22411 NN denotes cells
T14328 22412-22420 VB denotes required
T14329 22421-22446 JJ denotes high-antigen-dose-induced
T14330 22447-22451 NN denotes ERK1
T14331 22452-22455 CC denotes and
T14332 22456-22460 NN denotes ERK2
T14333 22461-22476 NN denotes phosphorylation
T14334 22477-22480 CC denotes and
T14335 22481-22494 JJ denotes IL-12-induced
T14336 22495-22501 NN denotes STAT-4
T14337 22502-22512 NN denotes activation
T14338 22513-22515 TO denotes to
T14339 22516-22523 VB denotes produce
T14340 22524-22529 NN denotes IL-10
T14341 22531-22534 PRP-DOLLAR- denotes Our
T14342 22535-22543 NN denotes findings
T14343 22544-22548 IN denotes that
T14344 22549-22553 NN denotes ERK1
T14345 22554-22557 CC denotes and
T14346 22558-22562 NN denotes ERK2
T14347 22563-22573 NN denotes activation
T14348 22574-22577 VB denotes was
T14349 22578-22579 DT denotes a
T14350 22580-22586 JJ denotes common
T14351 22587-22594 NN denotes pathway
T14352 22595-22603 VB denotes required
T14353 22604-22607 IN denotes for
T14354 22608-22611 DT denotes the
T14355 22612-22622 NN denotes production
T14356 22623-22625 IN denotes of
T14357 22626-22631 NN denotes IL-10
T14358 22632-22634 IN denotes by
T14359 22635-22638 NN denotes Th1
T14360 22638-22639 -COMMA- denotes ,
T14361 22640-22643 NN denotes Th2
T14362 22643-22644 -COMMA- denotes ,
T14363 22645-22648 CC denotes and
T14364 22649-22653 NN denotes Th17
T14365 22654-22658 NN denotes cell
T14366 22659-22666 NN denotes subsets
T14367 22666-22667 -COMMA- denotes ,
T14368 22668-22673 WDT denotes which
T14369 22674-22687 VB denotes differentiate
T14370 22688-22693 IN denotes along
T14371 22694-22702 JJ denotes distinct
T14372 22703-22711 NN denotes pathways
T14373 22711-22712 -COMMA- denotes ,
T14374 22713-22717 JJ denotes such
T14375 22718-22722 IN denotes that
T14376 22723-22728 NN denotes IL-10
T14377 22729-22737 VB denotes provides
T14378 22738-22739 DT denotes a
T14379 22740-22746 RB denotes highly
T14380 22747-22756 VB denotes regulated
T14381 22757-22765 NN denotes feedback
T14382 22766-22770 NN denotes loop
T14383 22771-22773 TO denotes to
T14384 22774-22779 VB denotes avoid
T14385 22780-22783 DT denotes the
T14386 22784-22792 NN denotes extremes
T14387 22793-22795 IN denotes of
T14388 22796-22805 JJ denotes excessive
T14389 22806-22818 NN denotes inflammation
T14390 22819-22821 CC denotes or
T14391 22822-22829 JJ denotes chronic
T14392 22830-22840 NN denotes infections
T14393 22841-22844 CC denotes and
T14394 22845-22849 RB denotes also
T14395 22850-22855 VB denotes allow
T14396 22856-22857 DT denotes a
T14397 22858-22868 JJ denotes protective
T14398 22869-22877 NN denotes response
T14399 22878-22880 TO denotes to
T14400 22881-22888 JJ denotes diverse
T14401 22889-22898 NN denotes pathogens
T14402 22900-22902 IN denotes In
T14403 22903-22910 JJ denotes certain
T14404 22911-22916 JJ denotes viral
T14405 22917-22919 CC denotes or
T14406 22920-22929 JJ denotes parasitic
T14407 22930-22940 NN denotes infections
T14408 22941-22942 -LRB- denotes (
T14409 22942-22950 NNP denotes Anderson
T14410 22951-22957 NNP denotes et al.
T14411 22957-22958 -COMMA- denotes ,
T14412 22959-22963 CD denotes 2007
T14413 22963-22964 -COLON- denotes ;
T14414 22965-22971 NNP denotes Brooks
T14415 22972-22978 FW denotes et al.
T14416 22978-22979 -COMMA- denotes ,
T14417 22980-22984 CD denotes 2006
T14418 22984-22985 -COLON- denotes ;
T14419 22986-22993 FW denotes Ejrnaes
T14420 22994-23000 FW denotes et al.
T14421 23000-23001 -COMMA- denotes ,
T14422 23002-23006 CD denotes 2006
T14423 23006-23007 -RRB- denotes )
T14424 23007-23008 -COMMA- denotes ,
T14425 23009-23013 JJ denotes high
T14426 23014-23021 NN denotes amounts
T14427 23022-23024 IN denotes of
T14428 23025-23036 NN denotes stimulation
T14429 23037-23040 MD denotes may
T14430 23041-23045 VB denotes lead
T14431 23046-23048 TO denotes to
T14432 23049-23052 DT denotes the
T14433 23053-23060 JJ denotes chronic
T14434 23061-23071 JJ denotes nonhealing
T14435 23072-23081 NN denotes infection
T14436 23082-23087 VB denotes shown
T14437 23088-23090 TO denotes to
T14438 23091-23093 VB denotes be
T14439 23094-23103 VB denotes regulated
T14440 23104-23106 IN denotes by
T14441 23107-23112 NN denotes IL-10
T14442 23114-23120 IN denotes During
T14443 23121-23124 DT denotes the
T14444 23125-23131 NN denotes course
T14445 23132-23134 IN denotes of
T14446 23135-23144 NN denotes infection
T14447 23144-23145 -COMMA- denotes ,
T14448 23146-23151 IN denotes after
T14449 23152-23159 JJ denotes initial
T14450 23160-23170 NN denotes triggering
T14451 23171-23175 IN denotes with
T14452 23176-23183 NN denotes antigen
T14453 23183-23184 -COMMA- denotes ,
T14454 23185-23192 NN denotes T cells
T14455 23193-23200 VB denotes migrate
T14456 23201-23203 TO denotes to
T14457 23204-23207 DT denotes the
T14458 23208-23214 NN denotes tissue
T14459 23215-23227 VB denotes encountering
T14460 23228-23232 JJ denotes high
T14461 23233-23238 NN denotes doses
T14462 23239-23241 IN denotes of
T14463 23242-23249 NN denotes antigen
T14464 23250-23253 CC denotes and
T14465 23254-23261 NN denotes factors
T14466 23262-23270 VB denotes produced
T14467 23271-23273 IN denotes by
T14468 23274-23277 DT denotes the
T14469 23278-23284 JJ denotes innate
T14470 23285-23291 JJ denotes immune
T14471 23292-23300 NN denotes response
T14472 23302-23307 IN denotes Under
T14473 23308-23313 DT denotes these
T14474 23314-23324 NN denotes conditions
T14475 23324-23325 -COMMA- denotes ,
T14476 23326-23328 PRP denotes we
T14477 23329-23338 VB denotes speculate
T14478 23339-23343 IN denotes that
T14479 23344-23347 NN denotes Th1
T14480 23348-23353 NN denotes cells
T14481 23354-23358 MD denotes will
T14482 23359-23361 VB denotes be
T14483 23362-23369 VB denotes induced
T14484 23370-23372 TO denotes to
T14485 23373-23380 VB denotes express
T14486 23381-23385 JJ denotes high
T14487 23386-23393 NN denotes amounts
T14488 23394-23396 IN denotes of
T14489 23397-23402 NN denotes IL-10
T14490 23402-23403 -COMMA- denotes ,
T14491 23404-23406 IN denotes in
T14492 23407-23414 VB denotes keeping
T14493 23415-23419 IN denotes with
T14494 23420-23427 NN denotes reports
T14495 23428-23432 IN denotes that
T14496 23433-23448 JJ denotes IL-10-producing
T14497 23449-23452 NN denotes Th1
T14498 23453-23458 NN denotes cells
T14499 23459-23463 VB denotes were
T14500 23464-23469 VB denotes found
T14501 23470-23472 IN denotes in
T14502 23473-23477 JJ denotes CD4+
T14503 23478-23484 NN denotes clones
T14504 23485-23493 VB denotes isolated
T14505 23494-23498 IN denotes from
T14506 23499-23502 NN denotes BAL
T14507 23503-23506 CC denotes but
T14508 23507-23510 RB denotes not
T14509 23511-23516 NN denotes blood
T14510 23517-23519 IN denotes of
T14511 23520-23522 NN denotes TB
T14512 23523-23531 NN denotes patients
T14513 23532-23533 -LRB- denotes (
T14514 23533-23539 NNP denotes Gerosa
T14515 23540-23546 NNP denotes et al.
T14516 23546-23547 -COMMA- denotes ,
T14517 23548-23552 CD denotes 1999
T14518 23552-23553 -RRB- denotes )
T14519 23555-23564 RB denotes Similarly
T14520 23564-23565 -COMMA- denotes ,
T14521 23566-23569 DT denotes the
T14522 23570-23576 JJ denotes immune
T14523 23577-23585 NN denotes response
T14524 23586-23588 TO denotes to
T14525 23589-23590 DT denotes a
T14526 23591-23599 JJ denotes clinical
T14527 23600-23607 NN denotes isolate
T14528 23608-23610 IN denotes of
T14529 23611-23613 NNP denotes L.
T14530 23614-23619 JJ denotes major
T14531 23619-23620 -COMMA- denotes ,
T14532 23621-23626 WDT denotes which
T14533 23627-23635 VB denotes produces
T14534 23636-23643 RB denotes heavily
T14535 23644-23652 JJ denotes infected
T14536 23653-23663 JJ denotes nonhealing
T14537 23664-23671 NN denotes lesions
T14538 23671-23672 -COMMA- denotes ,
T14539 23673-23676 VB denotes was
T14540 23677-23682 VB denotes found
T14541 23683-23685 TO denotes to
T14542 23686-23688 VB denotes be
T14543 23689-23698 VB denotes regulated
T14544 23699-23701 IN denotes by
T14545 23702-23707 NN denotes IL-10
T14546 23708-23715 VB denotes derived
T14547 23716-23720 IN denotes from
T14548 23721-23727 NN denotes Foxp3−
T14549 23728-23731 NN denotes Th1
T14550 23732-23737 NN denotes cells
T14551 23738-23742 WDT denotes that
T14552 23743-23752 VB denotes coproduce
T14553 23753-23758 NN denotes IL-10
T14554 23759-23762 CC denotes and
T14555 23763-23768 NN denotes IFN-γ
T14556 23769-23770 -LRB- denotes (
T14557 23770-23778 NNP denotes Anderson
T14558 23779-23785 NNP denotes et al.
T14559 23785-23786 -COMMA- denotes ,
T14560 23787-23791 CD denotes 2007
T14561 23791-23792 -RRB- denotes )
T14562 23792-23793 -COMMA- denotes ,
T14563 23794-23797 CC denotes and
T14564 23798-23801 DT denotes the
T14565 23802-23808 JJ denotes immune
T14566 23809-23817 NN denotes response
T14567 23818-23824 IN denotes during
T14568 23825-23827 FW denotes T.
T14569 23828-23834 FW denotes gondii
T14570 23835-23844 NN denotes infection
T14571 23845-23848 VB denotes was
T14572 23849-23854 VB denotes found
T14573 23855-23859 RB denotes also
T14574 23860-23862 TO denotes to
T14575 23863-23865 VB denotes be
T14576 23866-23875 VB denotes regulated
T14577 23876-23878 IN denotes by
T14578 23879-23885 NN denotes Foxp3−
T14579 23886-23889 NN denotes Th1
T14580 23890-23895 NN denotes cells
T14581 23896-23897 -LRB- denotes (
T14582 23897-23905 JJ denotes Jankovic
T14583 23906-23912 NN denotes et al.
T14584 23912-23913 -COMMA- denotes ,
T14585 23914-23918 CD denotes 2007
T14586 23918-23919 -RRB- denotes )
T14587 23921-23923 PRP denotes It
T14588 23924-23926 VB denotes is
T14589 23927-23933 JJ denotes likely
T14590 23934-23938 IN denotes that
T14591 23939-23944 NN denotes IL-10
T14592 23945-23955 NN denotes production
T14593 23956-23958 IN denotes by
T14594 23959-23962 NN denotes Th1
T14595 23963-23968 NN denotes cells
T14596 23969-23971 VB denotes is
T14597 23972-23978 VB denotes evoked
T14598 23979-23984 IN denotes under
T14599 23985-23995 NN denotes conditions
T14600 23996-23998 IN denotes of
T14601 23999-24003 JJ denotes high
T14602 24004-24016 NN denotes inflammation
T14603 24017-24020 CC denotes and
T14604 24021-24030 JJ denotes antigenic
T14605 24031-24042 NN denotes stimulation
T14606 24042-24043 -COMMA- denotes ,
T14607 24044-24051 IN denotes whereas
T14608 24052-24062 JJ denotes regulatory
T14609 24063-24067 JJ denotes CD4+
T14610 24068-24075 NN denotes T cells
T14611 24076-24085 VB denotes producing
T14612 24086-24091 NN denotes IL-10
T14613 24092-24095 MD denotes may
T14614 24096-24103 VB denotes operate
T14615 24104-24106 TO denotes to
T14616 24107-24115 VB denotes regulate
T14617 24116-24119 DT denotes the
T14618 24120-24126 JJ denotes immune
T14619 24127-24135 NN denotes response
T14620 24136-24141 IN denotes under
T14621 24142-24152 NN denotes conditions
T14622 24153-24155 IN denotes in
T14623 24156-24161 WDT denotes which
T14624 24162-24165 DT denotes the
T14625 24166-24174 NN denotes pathogen
T14626 24175-24177 VB denotes is
T14627 24178-24188 RB denotes clinically
T14628 24189-24199 VB denotes controlled
T14629 24199-24200 -COMMA- denotes ,
T14630 24201-24205 JJ denotes such
T14631 24206-24208 IN denotes as
T14632 24209-24211 IN denotes in
T14633 24212-24221 NN denotes infection
T14634 24222-24226 IN denotes with
T14635 24227-24229 FW denotes L.
T14636 24230-24235 JJ denotes major
T14637 24236-24237 -LRB- denotes (
T14638 24237-24245 NN denotes Friedlin
T14639 24246-24252 NN denotes strain
T14640 24252-24253 -RRB- denotes )
T14641 24254-24255 -LRB- denotes (
T14642 24255-24262 NNP denotes Belkaid
T14643 24263-24269 NNP denotes et al.
T14644 24269-24270 -COMMA- denotes ,
T14645 24271-24275 CD denotes 2002
T14646 24275-24276 -COLON- denotes ;
T14647 24277-24283 NNP denotes Suffia
T14648 24284-24290 FW denotes et al.
T14649 24290-24291 -COMMA- denotes ,
T14650 24292-24296 CD denotes 2006
T14651 24296-24297 -RRB- denotes )
T14652 24299-24301 PRP denotes We
T14653 24302-24305 RB denotes now
T14654 24306-24310 RB denotes also
T14655 24311-24319 VB denotes reported
T14656 24320-24324 IN denotes that
T14657 24325-24329 JJ denotes CD4+
T14658 24330-24337 NN denotes T cells
T14659 24338-24346 VB denotes cultured
T14660 24347-24351 IN denotes with
T14661 24352-24356 JJ denotes high
T14662 24357-24364 NN denotes antigen
T14663 24365-24369 NN denotes dose
T14664 24370-24373 CC denotes and
T14665 24374-24379 NN denotes IL-12
T14666 24380-24393 VB denotes differentiate
T14667 24394-24398 IN denotes into
T14668 24399-24408 JJ denotes canonical
T14669 24409-24412 NN denotes Th1
T14670 24413-24421 NN denotes effector
T14671 24422-24427 NN denotes cells
T14672 24427-24428 -COMMA- denotes ,
T14673 24429-24434 WDT denotes which
T14674 24434-24435 -COMMA- denotes ,
T14675 24436-24438 IN denotes in
T14676 24439-24447 NN denotes addition
T14677 24448-24450 TO denotes to
T14678 24451-24461 VB denotes expressing
T14679 24462-24467 JJ denotes large
T14680 24468-24475 NN denotes amounts
T14681 24476-24478 IN denotes of
T14682 24479-24484 NN denotes IFN-γ
T14683 24485-24488 CC denotes and
T14684 24489-24494 NN denotes IL-10
T14685 24494-24495 -COMMA- denotes ,
T14686 24496-24500 VB denotes lose
T14687 24501-24506 PRP-DOLLAR- denotes their
T14688 24507-24511 NN denotes IL-2
T14689 24512-24522 NN denotes expression
T14690 24523-24525 IN denotes as
T14691 24526-24535 VB denotes described
T14692 24536-24542 RB denotes before
T14693 24543-24545 IN denotes in
T14694 24546-24553 JJ denotes certain
T14695 24554-24561 JJ denotes chronic
T14696 24562-24571 NN denotes infection
T14697 24572-24578 NN denotes models
T14698 24579-24580 -LRB- denotes (
T14699 24580-24588 NNP denotes Sallusto
T14700 24589-24595 NNP denotes et al.
T14701 24595-24596 -COMMA- denotes ,
T14702 24597-24601 CD denotes 2004
T14703 24601-24602 -RRB- denotes )
T14704 24604-24607 PRP-DOLLAR- denotes Our
T14705 24608-24621 NN denotes demonstration
T14706 24622-24626 IN denotes that
T14707 24627-24631 NN denotes loss
T14708 24632-24634 IN denotes of
T14709 24635-24639 NN denotes IL-2
T14710 24640-24642 VB denotes is
T14711 24643-24654 VB denotes accompanied
T14712 24655-24657 IN denotes by
T14713 24658-24668 NN denotes production
T14714 24669-24671 IN denotes of
T14715 24672-24677 NN denotes IL-10
T14716 24678-24684 VB denotes offers
T14717 24685-24694 JJ denotes potential
T14718 24695-24705 JJ denotes additional
T14719 24706-24716 NN denotes mechanisms
T14720 24717-24724 WRB denotes whereby
T14721 24725-24733 NN denotes effector
T14722 24734-24740 NN denotes T cell
T14723 24741-24750 NN denotes responses
T14724 24751-24754 MD denotes may
T14725 24755-24757 VB denotes be
T14726 24758-24766 VB denotes dampened
T14727 24767-24773 IN denotes during
T14728 24774-24781 JJ denotes chronic
T14729 24782-24789 NN denotes disease
T14730 24791-24796 VB denotes Using
T14731 24797-24799 DT denotes an
T14732 24800-24807 FW denotes in vivo
T14733 24808-24816 NN denotes transfer
T14734 24817-24822 NN denotes model
T14735 24823-24825 IN denotes of
T14736 24826-24833 NN denotes DO11.10
T14737 24834-24837 NN denotes TCR
T14738 24838-24848 JJ denotes transgenic
T14739 24849-24854 NN denotes cells
T14740 24855-24856 -LRB- denotes (
T14741 24856-24862 NNP denotes Castro
T14742 24863-24869 FW denotes et al.
T14743 24869-24870 -COMMA- denotes ,
T14744 24871-24875 CD denotes 2000
T14745 24875-24876 -RRB- denotes )
T14746 24876-24877 -COMMA- denotes ,
T14747 24878-24880 PRP denotes we
T14748 24881-24887 VB denotes showed
T14749 24888-24892 IN denotes that
T14750 24893-24908 JJ denotes IL-10-producing
T14751 24909-24912 NN denotes Th1
T14752 24913-24918 NN denotes cells
T14753 24919-24923 VB denotes were
T14754 24924-24938 VB denotes differentiated
T14755 24939-24941 IN denotes in
T14756 24942-24945 DT denotes the
T14757 24946-24954 NN denotes presence
T14758 24955-24957 IN denotes of
T14759 24958-24962 JJ denotes high
T14760 24963-24968 NN denotes doses
T14761 24969-24971 IN denotes of
T14762 24972-24975 NN denotes OVA
T14763 24976-24983 NN denotes protein
T14764 24984-24987 CC denotes and
T14765 24988-24991 NN denotes LPS
T14766 24993-24995 PRP denotes We
T14767 24996-25002 VB denotes showed
T14768 25003-25007 RB denotes here
T14769 25008-25012 IN denotes that
T14770 25013-25017 DT denotes this
T14771 25018-25027 NN denotes induction
T14772 25028-25030 IN denotes of
T14773 25031-25036 NN denotes IL-10
T14774 25037-25043 NN denotes in Th1
T14775 25044-25049 NN denotes cells
T14776 25050-25057 FW denotes in vivo
T14777 25058-25061 VB denotes was
T14778 25062-25070 RB denotes markedly
T14779 25070-25071 -COMMA- denotes ,
T14780 25072-25075 CC denotes but
T14781 25076-25079 RB denotes not
T14782 25080-25087 RB denotes totally
T14783 25087-25088 -COMMA- denotes ,
T14784 25089-25096 VB denotes reduced
T14785 25097-25099 IN denotes in
T14786 25100-25115 JJ denotes STAT4-deficient
T14787 25116-25123 NN denotes T cells
T14788 25124-25126 IN denotes as
T14789 25127-25135 VB denotes observed
T14790 25136-25142 IN denotes during
T14791 25143-25145 FW denotes T.
T14792 25146-25152 NN denotes gondii
T14793 25153-25162 NN denotes infection
T14794 25163-25164 -LRB- denotes (
T14795 25164-25172 NNP denotes Jankovic
T14796 25173-25179 NNP denotes et al.
T14797 25179-25180 -COMMA- denotes ,
T14798 25181-25185 CD denotes 2002
T14799 25185-25186 -RRB- denotes )
T14800 25188-25189 DT denotes A
T14801 25190-25194 JJ denotes high
T14802 25195-25204 JJ denotes antigenic
T14803 25205-25215 NN denotes activation
T14804 25216-25222 IN denotes during
T14805 25223-25225 FW denotes T.
T14806 25226-25232 FW denotes gondii
T14807 25233-25242 NN denotes infection
T14808 25243-25245 CC denotes or
T14809 25246-25250 JJ denotes high
T14810 25251-25258 NN denotes antigen
T14811 25259-25264 NN denotes doses
T14812 25265-25274 VB denotes delivered
T14813 25275-25277 IN denotes in
T14814 25278-25281 DT denotes the
T14815 25282-25290 NN denotes presence
T14816 25291-25293 IN denotes of
T14817 25294-25297 NN denotes LPS
T14818 25297-25298 -COMMA- denotes ,
T14819 25299-25301 IN denotes as
T14820 25302-25306 VB denotes seen
T14821 25307-25309 IN denotes in
T14822 25310-25313 PRP-DOLLAR- denotes our
T14823 25314-25320 NN denotes system
T14824 25320-25321 -COMMA- denotes ,
T14825 25322-25325 MD denotes may
T14826 25326-25336 VB denotes compensate
T14827 25337-25340 IN denotes for
T14828 25341-25343 DT denotes an
T14829 25344-25352 JJ denotes absolute
T14830 25353-25364 NN denotes requirement
T14831 25365-25368 IN denotes for
T14832 25369-25374 NN denotes IL-12
T14833 25375-25377 IN denotes in
T14834 25378-25381 DT denotes the
T14835 25382-25391 NN denotes induction
T14836 25392-25394 IN denotes of
T14837 25395-25400 NN denotes IL-10
T14838 25401-25403 IN denotes by
T14839 25404-25407 NN denotes Th1
T14840 25408-25413 NN denotes cells
T14841 25415-25417 IN denotes In
T14842 25418-25421 PRP-DOLLAR- denotes our
T14843 25422-25430 FW denotes in vitro
T14844 25431-25437 NN denotes system
T14845 25437-25438 -COMMA- denotes ,
T14846 25439-25447 VB denotes repeated
T14847 25448-25459 NN denotes stimulation
T14848 25460-25462 IN denotes of
T14849 25463-25466 NN denotes Th1
T14850 25467-25472 NN denotes cells
T14851 25473-25477 IN denotes with
T14852 25478-25482 JJ denotes high
T14853 25483-25490 NN denotes antigen
T14854 25491-25496 NN denotes doses
T14855 25497-25504 VB denotes allowed
T14856 25505-25508 DT denotes the
T14857 25509-25520 NN denotes development
T14858 25521-25523 IN denotes of
T14859 25524-25527 NN denotes Th1
T14860 25528-25533 NN denotes cells
T14861 25534-25543 VB denotes producing
T14862 25544-25549 NN denotes IL-10
T14863 25550-25552 IN denotes in
T14864 25553-25555 DT denotes an
T14865 25556-25571 JJ denotes IL-12-dependent
T14866 25572-25578 NN denotes manner
T14867 25580-25585 NN denotes IL-10
T14868 25586-25596 NN denotes production
T14869 25597-25599 IN denotes by
T14870 25600-25603 NN denotes Th1
T14871 25604-25609 NN denotes cells
T14872 25610-25617 VB denotes induced
T14873 25618-25620 IN denotes by
T14874 25621-25625 JJ denotes high
T14875 25626-25633 NN denotes antigen
T14876 25634-25638 NN denotes dose
T14877 25639-25642 CC denotes and
T14878 25643-25648 NN denotes IL-12
T14879 25649-25652 VB denotes was
T14880 25653-25664 JJ denotes independent
T14881 25665-25667 IN denotes of
T14882 25668-25673 NN denotes IFN-γ
T14883 25673-25674 -COMMA- denotes ,
T14884 25675-25677 IN denotes in
T14885 25678-25685 VB denotes keeping
T14886 25686-25690 IN denotes with
T14887 25691-25699 JJ denotes previous
T14888 25700-25708 NN denotes findings
T14889 25709-25710 -LRB- denotes (
T14890 25710-25718 NNP denotes Jankovic
T14891 25719-25725 NNP denotes et al.
T14892 25725-25726 -COMMA- denotes ,
T14893 25727-25731 CD denotes 2002
T14894 25731-25732 -RRB- denotes )
T14895 25734-25741 RB denotes However
T14896 25741-25742 -COMMA- denotes ,
T14897 25743-25744 DT denotes a
T14898 25745-25749 NN denotes role
T14899 25750-25753 IN denotes for
T14900 25754-25759 NN denotes IFN-γ
T14901 25760-25762 IN denotes in
T14902 25763-25772 VB denotes mediating
T14903 25773-25778 NN denotes IL-10
T14904 25779-25791 NN denotes reactivation
T14905 25792-25794 IN denotes by
T14906 25795-25798 NN denotes Th1
T14907 25799-25804 NN denotes cells
T14908 25805-25811 IN denotes during
T14909 25812-25821 JJ denotes secondary
T14910 25822-25831 NN denotes infection
T14911 25832-25836 IN denotes with
T14912 25837-25839 NNP denotes T.
T14913 25840-25846 NN denotes gondii
T14914 25847-25850 VB denotes has
T14915 25851-25855 VB denotes been
T14916 25856-25865 VB denotes suggested
T14917 25866-25867 -LRB- denotes (
T14918 25867-25871 NNP denotes Shaw
T14919 25872-25878 NNP denotes et al.
T14920 25878-25879 -COMMA- denotes ,
T14921 25880-25884 CD denotes 2006
T14922 25884-25885 -RRB- denotes )
T14923 25887-25889 PRP denotes We
T14924 25890-25894 VB denotes have
T14925 25895-25900 VB denotes found
T14926 25901-25905 IN denotes that
T14927 25906-25910 JJ denotes CD4+
T14928 25911-25918 NN denotes T cells
T14929 25919-25926 VB denotes exposed
T14930 25927-25929 TO denotes to
T14931 25930-25931 DT denotes a
T14932 25932-25936 JJ denotes high
T14933 25937-25941 NN denotes dose
T14934 25942-25944 IN denotes of
T14935 25945-25952 NN denotes antigen
T14936 25953-25955 VB denotes do
T14937 25956-25959 RB denotes not
T14938 25960-25967 VB denotes express
T14939 25968-25973 NN denotes IL-10
T14940 25974-25978 IN denotes upon
T14941 25979-25992 NN denotes restimulation
T14942 25992-25993 -COMMA- denotes ,
T14943 25994-25997 CC denotes but
T14944 25998-26001 MD denotes can
T14945 26002-26004 VB denotes be
T14946 26005-26012 VB denotes induced
T14947 26013-26015 TO denotes to
T14948 26016-26023 VB denotes produce
T14949 26024-26029 NN denotes IL-10
T14950 26030-26034 IN denotes upon
T14951 26035-26046 NN denotes re-exposure
T14952 26047-26049 TO denotes to
T14953 26050-26051 DT denotes a
T14954 26052-26056 JJ denotes high
T14955 26057-26061 NN denotes dose
T14956 26062-26064 IN denotes of
T14957 26065-26072 NN denotes antigen
T14958 26073-26075 IN denotes in
T14959 26076-26079 DT denotes the
T14960 26080-26086 NN denotes recall
T14961 26087-26092 NN denotes phase
T14962 26093-26095 IN denotes in
T14963 26096-26099 DT denotes the
T14964 26100-26107 NN denotes absence
T14965 26108-26110 IN denotes of
T14966 26111-26116 VB denotes added
T14967 26117-26122 NN denotes IL-12
T14968 26124-26131 RB denotes However
T14969 26131-26132 -COMMA- denotes ,
T14970 26133-26137 DT denotes this
T14971 26138-26140 VB denotes is
T14972 26141-26150 JJ denotes dependent
T14973 26151-26153 IN denotes on
T14974 26154-26157 DT denotes the
T14975 26158-26167 NN denotes induction
T14976 26168-26170 IN denotes of
T14977 26171-26176 NN denotes IL-12
T14978 26177-26179 IN denotes by
T14979 26180-26198 JJ denotes antigen-presenting
T14980 26199-26202 NN denotes DCs
T14981 26204-26207 DT denotes The
T14982 26208-26219 NN denotes combination
T14983 26220-26222 IN denotes of
T14984 26223-26227 CC denotes both
T14985 26228-26232 JJ denotes high
T14986 26233-26240 NN denotes antigen
T14987 26241-26245 NN denotes dose
T14988 26246-26249 CC denotes and
T14989 26250-26255 NN denotes IL-12
T14990 26256-26264 VB denotes resulted
T14991 26265-26267 IN denotes in
T14992 26268-26271 DT denotes the
T14993 26272-26279 JJ denotes highest
T14994 26280-26286 NN denotes levels
T14995 26287-26289 IN denotes of
T14996 26290-26295 NN denotes IL-10
T14997 26296-26306 NN denotes production
T14998 26307-26310 CC denotes and
T14999 26311-26321 VB denotes correlated
T15000 26322-26326 IN denotes with
T15001 26327-26330 DT denotes the
T15002 26331-26335 JJ denotes high
T15003 26336-26342 NN denotes levels
T15004 26343-26345 IN denotes of
T15005 26346-26350 NN denotes ERK1
T15006 26351-26354 CC denotes and
T15007 26355-26359 NN denotes ERK2
T15008 26360-26370 NN denotes activation
T15009 26372-26375 DT denotes The
T15010 26376-26385 VB denotes increased
T15011 26386-26396 NN denotes expression
T15012 26397-26399 IN denotes of
T15013 26400-26405 NN denotes IFN-γ
T15014 26406-26414 VB denotes observed
T15015 26415-26421 IN denotes during
T15016 26422-26425 DT denotes the
T15017 26426-26435 JJ denotes secondary
T15018 26436-26441 NN denotes phase
T15019 26442-26446 MD denotes will
T15020 26447-26453 VB denotes induce
T15021 26454-26463 VB denotes increased
T15022 26464-26469 NN denotes IL-12
T15023 26470-26480 NN denotes production
T15024 26481-26483 IN denotes by
T15025 26484-26487 NN denotes DCs
T15026 26488-26491 CC denotes and
T15027 26492-26500 VB denotes suggests
T15028 26501-26505 IN denotes that
T15029 26506-26514 VB denotes repeated
T15030 26515-26525 JJ denotes high-level
T15031 26526-26529 NN denotes TCR
T15032 26530-26540 NN denotes activation
T15033 26541-26546 VB denotes feeds
T15034 26547-26551 RB denotes back
T15035 26552-26554 TO denotes to
T15036 26555-26565 VB denotes upregulate
T15037 26566-26571 NN denotes IL-12
T15038 26572-26582 NN denotes production
T15039 26583-26585 IN denotes by
T15040 26586-26588 NN denotes DC
T15041 26590-26592 PRP denotes It
T15042 26593-26595 VB denotes is
T15043 26596-26600 RB denotes thus
T15044 26601-26607 JJ denotes likely
T15045 26608-26612 IN denotes that
T15046 26613-26615 IN denotes in
T15047 26616-26618 FW denotes T.
T15048 26619-26625 FW denotes gondii
T15049 26626-26635 NN denotes infection
T15050 26636-26643 FW denotes in vivo
T15051 26644-26645 -LRB- denotes (
T15052 26645-26649 NNP denotes Shaw
T15053 26650-26656 NNP denotes et al.
T15054 26656-26657 -COMMA- denotes ,
T15055 26658-26662 CD denotes 2006
T15056 26662-26663 -RRB- denotes )
T15057 26663-26664 -COMMA- denotes ,
T15058 26665-26668 DT denotes the
T15059 26669-26680 NN denotes requirement
T15060 26681-26684 IN denotes for
T15061 26685-26690 NN denotes IFN-γ
T15062 26691-26693 TO denotes to
T15063 26694-26700 VB denotes induce
T15064 26701-26706 NN denotes IL-10
T15065 26706-26707 -COMMA- denotes ,
T15066 26708-26711 VB denotes was
T15067 26712-26715 IN denotes for
T15068 26716-26724 NN denotes feedback
T15069 26725-26737 NN denotes upregulation
T15070 26738-26740 IN denotes of
T15071 26741-26746 NN denotes IL-12
T15072 26747-26749 IN denotes by
T15073 26750-26753 NN denotes DCs
T15074 26753-26754 -COMMA- denotes ,
T15075 26755-26760 WDT denotes which
T15076 26761-26763 IN denotes in
T15077 26764-26768 NN denotes turn
T15078 26769-26776 VB denotes induced
T15079 26777-26782 NN denotes IL-10
T15080 26783-26785 IN denotes in
T15081 26786-26789 DT denotes the
T15082 26790-26793 NN denotes Th1
T15083 26794-26799 NN denotes cells
T15084 26801-26809 IN denotes Although
T15085 26810-26815 NN denotes IL-10
T15086 26816-26819 MD denotes may
T15087 26820-26822 VB denotes be
T15088 26823-26837 RB denotes differentially
T15089 26838-26847 VB denotes regulated
T15090 26848-26850 IN denotes in
T15091 26851-26854 NN denotes Th1
T15092 26855-26858 CC denotes and
T15093 26859-26862 NN denotes Th2
T15094 26863-26868 NN denotes cells
T15095 26869-26871 IN denotes as
T15096 26872-26875 VB denotes has
T15097 26876-26880 VB denotes been
T15098 26881-26889 VB denotes reported
T15099 26890-26891 -LRB- denotes (
T15100 26891-26896 NNP denotes Chang
T15101 26897-26903 NNP denotes et al.
T15102 26903-26904 -COMMA- denotes ,
T15103 26905-26909 CD denotes 2007
T15104 26909-26910 -COLON- denotes ;
T15105 26911-26915 NNP denotes Wang
T15106 26916-26922 FW denotes et al.
T15107 26922-26923 -COMMA- denotes ,
T15108 26924-26928 CD denotes 2005
T15109 26928-26929 -RRB- denotes )
T15110 26929-26930 -COMMA- denotes ,
T15111 26931-26935 DT denotes some
T15112 26936-26943 NN denotes studies
T15113 26944-26951 VB denotes suggest
T15114 26952-26955 DT denotes the
T15115 26956-26965 NN denotes existence
T15116 26966-26968 IN denotes of
T15117 26969-26975 JJ denotes common
T15118 26976-26984 NN denotes pathways
T15119 26984-26985 -COMMA- denotes ,
T15120 26986-26989 CC denotes but
T15121 26990-26993 DT denotes the
T15122 26994-27003 JJ denotes molecular
T15123 27004-27009 NN denotes basis
T15124 27010-27013 IN denotes for
T15125 27014-27019 DT denotes these
T15126 27020-27022 VB denotes is
T15127 27023-27025 RB denotes as
T15128 27026-27029 RB denotes yet
T15129 27030-27037 JJ denotes unclear
T15130 27039-27052 JJ denotes Costimulatory
T15131 27053-27058 NN denotes OX-40
T15132 27059-27066 NN denotes signals
T15133 27067-27071 VB denotes have
T15134 27072-27076 VB denotes been
T15135 27077-27082 VB denotes shown
T15136 27083-27085 TO denotes to
T15137 27086-27096 RB denotes negatively
T15138 27097-27105 VB denotes regulate
T15139 27106-27111 NN denotes IL-10
T15140 27112-27122 NN denotes production
T15141 27123-27124 -LRB- denotes (
T15142 27124-27127 NNP denotes Ito
T15143 27128-27134 NNP denotes et al.
T15144 27134-27135 -COMMA- denotes ,
T15145 27136-27140 CD denotes 2005
T15146 27140-27141 -RRB- denotes )
T15147 27142-27146 CC denotes both
T15148 27147-27149 IN denotes in
T15149 27150-27153 NN denotes Th1
T15150 27154-27157 CC denotes and
T15151 27158-27161 NN denotes Th2
T15152 27162-27167 NN denotes cells
T15153 27167-27168 -COMMA- denotes ,
T15154 27169-27176 IN denotes whereas
T15155 27177-27181 NN denotes ICOS
T15156 27182-27191 NN denotes signaling
T15157 27192-27195 VB denotes has
T15158 27196-27200 VB denotes been
T15159 27201-27210 VB denotes suggested
T15160 27211-27213 TO denotes to
T15161 27214-27220 VB denotes induce
T15162 27221-27226 NN denotes IL-10
T15163 27227-27228 -LRB- denotes (
T15164 27228-27231 NNP denotes Ito
T15165 27232-27238 NNP denotes et al.
T15166 27238-27239 -COMMA- denotes ,
T15167 27240-27244 CD denotes 2007
T15168 27244-27245 -COLON- denotes ;
T15169 27246-27252 NNP denotes Witsch
T15170 27253-27259 NNP denotes et al.
T15171 27259-27260 -COMMA- denotes ,
T15172 27261-27265 CD denotes 2002
T15173 27265-27266 -RRB- denotes )
T15174 27267-27269 IN denotes in
T15175 27270-27274 CC denotes both
T15176 27275-27278 NN denotes Th1
T15177 27279-27282 CC denotes and
T15178 27283-27286 NN denotes Th2
T15179 27287-27292 NN denotes cells
T15180 27294-27301 RB denotes However
T15181 27301-27302 -COMMA- denotes ,
T15182 27303-27305 IN denotes in
T15183 27306-27310 DT denotes some
T15184 27311-27316 NN denotes cases
T15185 27316-27317 -COMMA- denotes ,
T15186 27318-27322 NN denotes ICOS
T15187 27323-27332 NN denotes signaling
T15188 27333-27337 RB denotes also
T15189 27338-27347 VB denotes regulates
T15190 27348-27352 NN denotes IL-4
T15191 27353-27363 NN denotes production
T15192 27364-27367 CC denotes and
T15193 27368-27371 NN denotes Th2
T15194 27372-27381 NN denotes responses
T15195 27382-27383 -LRB- denotes (
T15196 27383-27392 NNP denotes Greenwald
T15197 27393-27399 NNP denotes et al.
T15198 27399-27400 -COMMA- denotes ,
T15199 27401-27405 CD denotes 2005
T15200 27405-27406 -RRB- denotes )
T15201 27408-27410 PRP denotes We
T15202 27411-27414 RB denotes now
T15203 27415-27422 VB denotes provide
T15204 27423-27424 DT denotes a
T15205 27425-27431 JJ denotes common
T15206 27432-27441 NN denotes mechanism
T15207 27442-27444 IN denotes of
T15208 27445-27449 NN denotes ERK1
T15209 27450-27453 CC denotes and
T15210 27454-27458 NN denotes ERK2
T15211 27459-27469 NN denotes activation
T15212 27470-27473 IN denotes for
T15213 27474-27477 DT denotes the
T15214 27478-27488 NN denotes regulation
T15215 27489-27491 IN denotes of
T15216 27492-27497 NN denotes IL-10
T15217 27498-27508 NN denotes production
T15218 27509-27511 IN denotes in
T15219 27512-27515 NN denotes Th1
T15220 27515-27516 -COMMA- denotes ,
T15221 27517-27520 NN denotes Th2
T15222 27520-27521 -COMMA- denotes ,
T15223 27522-27525 CC denotes and
T15224 27526-27530 NN denotes Th17
T15225 27531-27536 NN denotes cells
T15226 27536-27537 -COMMA- denotes ,
T15227 27538-27546 IN denotes although
T15228 27547-27551 DT denotes each
T15229 27552-27558 NN denotes subset
T15230 27559-27573 VB denotes differentiates
T15231 27574-27579 IN denotes along
T15232 27580-27581 DT denotes a
T15233 27582-27590 JJ denotes distinct
T15234 27591-27594 CC denotes and
T15235 27595-27610 JJ denotes subset-specific
T15236 27611-27626 JJ denotes transcriptional
T15237 27627-27634 NN denotes pathway
T15238 27636-27640 DT denotes This
T15239 27641-27651 VB denotes reinforces
T15240 27652-27655 DT denotes the
T15241 27656-27660 NN denotes fact
T15242 27661-27665 IN denotes that
T15243 27666-27671 NN denotes IL-10
T15244 27672-27674 VB denotes is
T15245 27675-27678 RB denotes not
T15246 27679-27680 DT denotes a
T15247 27681-27683 NN denotes Th
T15248 27684-27704 JJ denotes cell-subset-specific
T15249 27705-27713 NN denotes cytokine
T15250 27713-27714 -COMMA- denotes ,
T15251 27715-27718 CC denotes but
T15252 27719-27726 RB denotes instead
T15253 27727-27729 VB denotes is
T15254 27730-27738 VB denotes produced
T15255 27739-27741 IN denotes in
T15256 27742-27743 DT denotes a
T15257 27744-27751 RB denotes tightly
T15258 27752-27761 VB denotes regulated
T15259 27762-27769 NN denotes fashion
T15260 27770-27776 IN denotes during
T15261 27777-27781 DT denotes each
T15262 27782-27797 NN denotes differentiation
T15263 27798-27805 NN denotes pathway
T15264 27807-27809 IN denotes Of
T15265 27810-27814 NN denotes note
T15266 27814-27815 -COMMA- denotes ,
T15267 27816-27817 DT denotes a
T15268 27818-27822 NN denotes role
T15269 27823-27826 IN denotes for
T15270 27827-27831 NN denotes ERK1
T15271 27832-27835 CC denotes and
T15272 27836-27840 NN denotes ERK2
T15273 27841-27851 NN denotes activation
T15274 27852-27854 IN denotes in
T15275 27855-27858 DT denotes the
T15276 27859-27868 NN denotes induction
T15277 27869-27871 IN denotes of
T15278 27872-27877 NN denotes IL-10
T15279 27878-27888 NN denotes production
T15280 27889-27892 VB denotes has
T15281 27893-27900 RB denotes already
T15282 27901-27905 VB denotes been
T15283 27906-27915 VB denotes described
T15284 27916-27919 IN denotes for
T15285 27920-27931 NN denotes macrophages
T15286 27932-27935 CC denotes and
T15287 27936-27938 NN denotes DC
T15288 27939-27940 -LRB- denotes (
T15289 27940-27947 NNP denotes Agrawal
T15290 27948-27954 NNP denotes et al.
T15291 27954-27955 -COMMA- denotes ,
T15292 27956-27960 CD denotes 2006
T15293 27960-27961 -COLON- denotes ;
T15294 27962-27968 NNP denotes Hacker
T15295 27969-27975 FW denotes et al.
T15296 27975-27976 -COMMA- denotes ,
T15297 27977-27981 CD denotes 1999
T15298 27981-27982 -RRB- denotes )
T15299 27984-27996 JJ denotes Differential
T15300 27997-28012 JJ denotes transcriptional
T15301 28013-28023 NN denotes regulation
T15302 28024-28026 IN denotes of
T15303 28027-28032 NN denotes IL-10
T15304 28033-28035 IN denotes in
T15305 28036-28039 NN denotes Th1
T15306 28040-28043 CC denotes and
T15307 28044-28047 NN denotes Th2
T15308 28048-28053 NN denotes cells
T15309 28054-28057 VB denotes has
T15310 28058-28062 VB denotes been
T15311 28063-28072 VB denotes suggested
T15312 28073-28074 -LRB- denotes (
T15313 28074-28079 NNP denotes Chang
T15314 28080-28086 NNP denotes et al.
T15315 28086-28087 -COMMA- denotes ,
T15316 28088-28092 CD denotes 2007
T15317 28092-28093 -COLON- denotes ;
T15318 28094-28098 NNP denotes Wang
T15319 28099-28105 FW denotes et al.
T15320 28105-28106 -COMMA- denotes ,
T15321 28107-28111 CD denotes 2005
T15322 28111-28112 -RRB- denotes )
T15323 28112-28113 -COMMA- denotes ,
T15324 28114-28117 CC denotes and
T15325 28118-28127 JJ denotes extensive
T15326 28128-28135 NN denotes histone
T15327 28136-28147 NN denotes acetylation
T15328 28148-28150 IN denotes of
T15329 28151-28154 DT denotes the
T15330 28155-28160 NN denotes IL-10
T15331 28161-28165 NN denotes gene
T15332 28166-28168 VB denotes is
T15333 28169-28179 JJ denotes detectable
T15334 28180-28182 IN denotes in
T15335 28183-28188 RB denotes fully
T15336 28189-28198 VB denotes polarized
T15337 28199-28202 NN denotes Th2
T15338 28203-28208 NN denotes cells
T15339 28208-28209 -COMMA- denotes ,
T15340 28210-28213 CC denotes but
T15341 28214-28217 RB denotes not
T15342 28218-28221 NN denotes Th1
T15343 28222-28227 NN denotes cells
T15344 28228-28229 -LRB- denotes (
T15345 28229-28234 NNP denotes Chang
T15346 28235-28241 NNP denotes et al.
T15347 28241-28242 -COMMA- denotes ,
T15348 28243-28247 CD denotes 2007
T15349 28247-28248 -RRB- denotes )
T15350 28250-28252 PRP denotes We
T15351 28253-28260 VB denotes provide
T15352 28261-28269 NN denotes evidence
T15353 28270-28274 IN denotes that
T15354 28275-28280 NN denotes IL-10
T15355 28281-28283 VB denotes is
T15356 28284-28292 VB denotes produced
T15357 28293-28295 IN denotes in
T15358 28296-28305 JJ denotes canonical
T15359 28306-28309 NN denotes Th1
T15360 28310-28315 NN denotes cells
T15361 28316-28319 CC denotes and
T15362 28320-28324 IN denotes that
T15363 28325-28328 PRP-DOLLAR- denotes its
T15364 28329-28339 NN denotes expression
T15365 28340-28350 VB denotes correlates
T15366 28351-28355 IN denotes with
T15367 28356-28359 DT denotes the
T15368 28360-28370 NN denotes expression
T15369 28371-28373 IN denotes of
T15370 28374-28379 NN denotes T-bet
T15371 28380-28383 CC denotes and
T15372 28384-28387 DT denotes the
T15373 28388-28395 JJ denotes highest
T15374 28396-28401 NN denotes IFN-γ
T15375 28402-28412 NN denotes production
T15376 28412-28413 -COMMA- denotes ,
T15377 28414-28416 IN denotes in
T15378 28417-28424 VB denotes keeping
T15379 28425-28429 IN denotes with
T15380 28430-28433 PRP-DOLLAR- denotes our
T15381 28434-28446 NN denotes observations
T15382 28447-28451 IN denotes that
T15383 28452-28461 JJ denotes high-dose
T15384 28462-28469 NN denotes antigen
T15385 28470-28481 NN denotes stimulation
T15386 28482-28485 CC denotes and
T15387 28486-28491 NN denotes IL-12
T15388 28492-28501 NN denotes signaling
T15389 28502-28505 VB denotes are
T15390 28506-28514 VB denotes required
T15391 28515-28518 IN denotes for
T15392 28519-28524 NN denotes IL-10
T15393 28525-28528 CC denotes and
T15394 28529-28534 NN denotes IFN-γ
T15395 28535-28545 NN denotes expression
T15396 28547-28549 PRP denotes It
T15397 28550-28553 VB denotes has
T15398 28554-28558 RB denotes also
T15399 28559-28563 VB denotes been
T15400 28564-28569 VB denotes shown
T15401 28570-28574 IN denotes that
T15402 28575-28586 NN denotes maintenance
T15403 28587-28589 IN denotes of
T15404 28590-28595 NN denotes IL-10
T15405 28596-28606 NN denotes expression
T15406 28607-28609 VB denotes is
T15407 28610-28621 JJ denotes conditional
T15408 28622-28624 IN denotes on
T15409 28625-28630 NN denotes IL-12
T15410 28631-28633 CC denotes or
T15411 28634-28638 NN denotes IL-4
T15412 28639-28645 IN denotes unless
T15413 28646-28649 DT denotes the
T15414 28650-28655 NN denotes IL-10
T15415 28656-28660 NN denotes gene
T15416 28661-28663 VB denotes is
T15417 28664-28673 VB denotes imprinted
T15418 28674-28676 IN denotes by
T15419 28677-28683 NN denotes GATA-3
T15420 28684-28685 -LRB- denotes (
T15421 28685-28690 NNP denotes Chang
T15422 28691-28697 NNP denotes et al.
T15423 28697-28698 -COMMA- denotes ,
T15424 28699-28703 CD denotes 2007
T15425 28703-28704 -RRB- denotes )
T15426 28704-28705 -COMMA- denotes ,
T15427 28706-28711 WDT denotes which
T15428 28712-28715 MD denotes can
T15429 28716-28723 VB denotes remodel
T15430 28724-28727 DT denotes the
T15431 28728-28733 NN denotes IL-10
T15432 28734-28739 NN denotes locus
T15433 28739-28740 -COMMA- denotes ,
T15434 28741-28745 RB denotes thus
T15435 28746-28756 VB denotes explaining
T15436 28757-28760 DT denotes the
T15437 28761-28768 JJ denotes highest
T15438 28769-28776 NN denotes amounts
T15439 28777-28779 IN denotes of
T15440 28780-28785 NN denotes IL-10
T15441 28786-28794 VB denotes produced
T15442 28795-28797 IN denotes by
T15443 28798-28801 NN denotes Th2
T15444 28802-28807 NN denotes cells
T15445 28808-28809 -LRB- denotes (
T15446 28809-28814 NNP denotes Chang
T15447 28815-28821 NNP denotes et al.
T15448 28821-28822 -COMMA- denotes ,
T15449 28823-28827 CD denotes 2007
T15450 28827-28828 -COLON- denotes ;
T15451 28829-28838 NNP denotes Shoemaker
T15452 28839-28845 FW denotes et al.
T15453 28845-28846 -COMMA- denotes ,
T15454 28847-28851 CD denotes 2006
T15455 28851-28852 -RRB- denotes )
T15456 28854-28856 PRP denotes We
T15457 28857-28861 VB denotes show
T15458 28862-28866 RB denotes here
T15459 28867-28871 IN denotes that
T15460 28872-28876 JJ denotes high
T15461 28877-28884 NN denotes antigen
T15462 28885-28889 NN denotes dose
T15463 28890-28893 CC denotes and
T15464 28894-28899 NN denotes IL-12
T15465 28900-28911 RB denotes drastically
T15466 28912-28924 VB denotes downregulate
T15467 28925-28931 NN denotes Gata-3
T15468 28932-28942 NN denotes expression
T15469 28942-28943 -COMMA- denotes ,
T15470 28944-28954 VB denotes suggesting
T15471 28955-28959 IN denotes that
T15472 28960-28970 JJ denotes additional
T15473 28971-28978 NN denotes factors
T15474 28979-28982 VB denotes are
T15475 28983-28985 IN denotes in
T15476 28986-28991 NN denotes place
T15477 28992-28994 TO denotes to
T15478 28995-29001 VB denotes induce
T15479 29002-29007 NN denotes IL-10
T15480 29008-29018 NN denotes expression
T15481 29019-29021 IN denotes in
T15482 29022-29025 NN denotes Th1
T15483 29026-29031 NN denotes cells
T15484 29031-29032 -COMMA- denotes ,
T15485 29033-29039 IN denotes albeit
T15486 29040-29051 RB denotes transiently
T15487 29053-29063 NN denotes Expression
T15488 29064-29066 IN denotes of
T15489 29067-29072 NN denotes c-maf
T15490 29073-29076 VB denotes was
T15491 29077-29084 RB denotes greatly
T15492 29085-29095 VB denotes diminished
T15493 29096-29098 IN denotes by
T15494 29099-29103 JJ denotes high
T15495 29104-29111 NN denotes antigen
T15496 29112-29117 NN denotes doses
T15497 29118-29120 IN denotes in
T15498 29121-29128 NN denotes T cells
T15499 29129-29132 CC denotes and
T15500 29133-29136 RB denotes yet
T15501 29137-29140 VB denotes was
T15502 29141-29153 RB denotes unexpectedly
T15503 29154-29164 VB denotes maintained
T15504 29165-29167 IN denotes by
T15505 29168-29173 NN denotes IL-12
T15506 29174-29177 CC denotes and
T15507 29178-29185 JJ denotes present
T15508 29186-29188 IN denotes in
T15509 29189-29193 NN denotes Th17
T15510 29194-29199 NN denotes cells
T15511 29201-29205 DT denotes That
T15512 29206-29211 NN denotes c-maf
T15513 29212-29222 NN denotes expression
T15514 29223-29225 VB denotes is
T15515 29226-29232 JJ denotes common
T15516 29233-29235 TO denotes to
T15517 29236-29251 JJ denotes IL-10-producing
T15518 29252-29255 NN denotes Th1
T15519 29255-29256 -COMMA- denotes ,
T15520 29257-29260 NN denotes Th2
T15521 29260-29261 -COMMA- denotes ,
T15522 29262-29265 CC denotes and
T15523 29266-29270 NN denotes Th17
T15524 29271-29276 NN denotes cells
T15525 29277-29280 CC denotes and
T15526 29280-29281 -COMMA- denotes ,
T15527 29282-29286 IN denotes like
T15528 29287-29292 NN denotes IL-10
T15529 29292-29293 -COMMA- denotes ,
T15530 29294-29296 VB denotes is
T15531 29297-29306 JJ denotes dependent
T15532 29307-29309 IN denotes on
T15533 29310-29313 NN denotes ERK
T15534 29314-29324 NN denotes activation
T15535 29325-29327 IN denotes in
T15536 29328-29331 NN denotes Th1
T15537 29332-29335 CC denotes and
T15538 29336-29340 NN denotes Th17
T15539 29341-29346 NN denotes cells
T15540 29347-29350 IN denotes for
T15541 29351-29354 PRP-DOLLAR- denotes its
T15542 29355-29365 NN denotes expression
T15543 29366-29368 VB denotes is
T15544 29369-29371 IN denotes of
T15545 29372-29380 NN denotes interest
T15546 29381-29388 IN denotes because
T15547 29389-29394 NN denotes c-Maf
T15548 29395-29398 VB denotes has
T15549 29399-29403 VB denotes been
T15550 29404-29409 VB denotes shown
T15551 29410-29412 TO denotes to
T15552 29413-29415 VB denotes be
T15553 29416-29418 DT denotes an
T15554 29419-29428 JJ denotes essential
T15555 29429-29442 NN denotes transcription
T15556 29443-29449 NN denotes factor
T15557 29450-29453 IN denotes for
T15558 29454-29459 NN denotes IL-10
T15559 29460-29470 NN denotes expression
T15560 29471-29473 IN denotes in
T15561 29474-29485 NN denotes macrophages
T15562 29486-29487 -LRB- denotes (
T15563 29487-29490 NNP denotes Cao
T15564 29491-29497 NNP denotes et al.
T15565 29497-29498 -COMMA- denotes ,
T15566 29499-29503 CD denotes 2005
T15567 29503-29504 -RRB- denotes )
T15568 29506-29508 IN denotes In
T15569 29509-29516 NN denotes summary
T15570 29516-29517 -COMMA- denotes ,
T15571 29518-29520 PRP denotes we
T15572 29521-29525 VB denotes show
T15573 29526-29530 IN denotes that
T15574 29531-29539 IN denotes although
T15575 29540-29543 NN denotes Th1
T15576 29543-29544 -COMMA- denotes ,
T15577 29545-29548 NN denotes Th2
T15578 29548-29549 -COMMA- denotes ,
T15579 29550-29553 CC denotes and
T15580 29554-29558 NN denotes Th17
T15581 29559-29563 JJ denotes CD4+
T15582 29564-29570 NN denotes T cell
T15583 29571-29578 NN denotes subsets
T15584 29579-29592 VB denotes differentiate
T15585 29593-29598 IN denotes along
T15586 29599-29607 JJ denotes distinct
T15587 29608-29617 NN denotes signaling
T15588 29618-29621 CC denotes and
T15589 29622-29637 JJ denotes transcriptional
T15590 29638-29646 NN denotes pathways
T15591 29646-29647 -COMMA- denotes ,
T15592 29648-29652 PRP denotes they
T15593 29653-29656 MD denotes can
T15594 29657-29660 DT denotes all
T15595 29661-29663 VB denotes be
T15596 29664-29671 VB denotes induced
T15597 29672-29674 TO denotes to
T15598 29675-29679 VB denotes make
T15599 29680-29685 NN denotes IL-10
T15600 29687-29691 NN denotes ERK1
T15601 29692-29695 CC denotes and
T15602 29696-29700 NN denotes ERK2
T15603 29701-29711 NN denotes activation
T15604 29712-29714 VB denotes is
T15605 29715-29723 VB denotes required
T15606 29724-29727 IN denotes for
T15607 29728-29733 NN denotes IL-10
T15608 29734-29744 NN denotes production
T15609 29745-29747 IN denotes by
T15610 29748-29751 PDT denotes all
T15611 29752-29757 DT denotes these
T15612 29758-29760 NN denotes Th
T15613 29761-29765 NN denotes cell
T15614 29766-29773 NN denotes subsets
T15615 29775-29779 IN denotes With
T15616 29780-29786 NN denotes regard
T15617 29787-29789 TO denotes to
T15618 29790-29793 DT denotes the
T15619 29794-29804 NN denotes expression
T15620 29805-29807 IN denotes of
T15621 29808-29813 NN denotes IL-10
T15622 29814-29816 IN denotes by
T15623 29817-29820 NN denotes Th1
T15624 29821-29826 NN denotes cells
T15625 29826-29827 -COMMA- denotes ,
T15626 29828-29831 PRP-DOLLAR- denotes our
T15627 29832-29836 NN denotes data
T15628 29837-29844 VB denotes provide
T15629 29845-29846 DT denotes a
T15630 29847-29856 NN denotes mechanism
T15631 29857-29860 IN denotes for
T15632 29861-29864 WRB denotes how
T15633 29865-29870 NN denotes IL-10
T15634 29871-29881 NN denotes expression
T15635 29882-29884 VB denotes is
T15636 29885-29892 VB denotes induced
T15637 29893-29896 CC denotes and
T15638 29897-29901 RB denotes then
T15639 29902-29911 VB denotes amplified
T15640 29912-29915 CC denotes and
T15641 29916-29925 VB denotes regulated
T15642 29926-29928 IN denotes by
T15643 29929-29932 DT denotes the
T15644 29933-29939 NN denotes levels
T15645 29940-29942 IN denotes of
T15646 29943-29950 NN denotes antigen
T15647 29951-29954 CC denotes and
T15648 29955-29960 NN denotes IL-12
T15649 29961-29972 VB denotes encountered
T15650 29973-29975 IN denotes in
T15651 29976-29979 DT denotes the
T15652 29980-29991 NN denotes environment
T15653 29993-29997 DT denotes This
T15654 29998-30006 VB denotes provides
T15655 30007-30008 DT denotes a
T15656 30009-30018 NN denotes mechanism
T15657 30019-30026 WRB denotes whereby
T15658 30027-30028 DT denotes a
T15659 30029-30032 NN denotes Th1
T15660 30033-30037 NN denotes cell
T15661 30038-30046 VB denotes responds
T15662 30047-30049 TO denotes to
T15663 30050-30059 JJ denotes extrinsic
T15664 30060-30067 NN denotes signals
T15665 30067-30068 -COMMA- denotes ,
T15666 30069-30079 VB denotes reflecting
T15667 30080-30089 VB denotes increased
T15668 30090-30102 NN denotes inflammation
T15669 30103-30105 IN denotes in
T15670 30106-30109 DT denotes the
T15671 30110-30116 NN denotes tissue
T15672 30116-30117 -COMMA- denotes ,
T15673 30118-30120 TO denotes to
T15674 30121-30128 RB denotes tightly
T15675 30129-30137 VB denotes regulate
T15676 30138-30141 DT denotes the
T15677 30142-30152 NN denotes production
T15678 30153-30155 IN denotes of
T15679 30156-30161 NN denotes IL-10
T15680 30162-30164 RB denotes so
T15681 30165-30167 IN denotes as
T15682 30168-30170 TO denotes to
T15683 30171-30176 VB denotes allow
T15684 30177-30178 DT denotes a
T15685 30179-30189 JJ denotes protective
T15686 30190-30198 NN denotes response
T15687 30199-30201 TO denotes to
T15688 30202-30211 VB denotes eradicate
T15689 30212-30213 DT denotes a
T15690 30214-30222 NN denotes pathogen
T15691 30223-30227 IN denotes with
T15692 30228-30235 JJ denotes minimal
T15693 30236-30242 NN denotes damage
T15694 30243-30245 TO denotes to
T15695 30246-30249 DT denotes the
T15696 30250-30254 NN denotes host
T15697 30255-30258 CC denotes and
T15698 30259-30263 RB denotes also
T15699 30264-30271 VB denotes prevent
T15700 30272-30279 JJ denotes chronic
T15701 30280-30289 NN denotes infection
T15702 30291-30299 RB denotes Moreover
T15703 30299-30300 -COMMA- denotes ,
T15704 30301-30304 PRP-DOLLAR- denotes our
T15705 30305-30313 NN denotes findings
T15706 30314-30318 VB denotes have
T15707 30319-30328 JJ denotes important
T15708 30329-30341 NN denotes implications
T15709 30342-30345 IN denotes for
T15710 30346-30349 DT denotes the
T15711 30350-30360 NN denotes regulation
T15712 30361-30363 IN denotes of
T15713 30364-30369 NN denotes IL-10
T15714 30370-30380 NN denotes production
T15715 30381-30387 IN denotes during
T15716 30388-30390 DT denotes an
T15717 30391-30403 JJ denotes inflammatory
T15718 30404-30407 NN denotes Th1
T15719 30408-30416 NN denotes response
T15720 30417-30419 IN denotes in
T15721 30420-30429 NN denotes infection
T15722 30430-30433 CC denotes and
T15723 30434-30437 MD denotes may
T15724 30438-30440 VB denotes be
T15725 30441-30443 IN denotes of
T15726 30444-30453 NN denotes relevance
T15727 30454-30457 IN denotes for
T15728 30458-30461 DT denotes the
T15729 30462-30468 NN denotes design
T15730 30469-30471 IN denotes of
T15731 30472-30480 NN denotes vaccines
T15732 30481-30484 CC denotes and
T15733 30485-30488 IN denotes for
T15734 30489-30499 NN denotes strategies
T15735 30500-30502 IN denotes in
T15736 30503-30516 NN denotes immunotherapy
T15737 30517-30519 IN denotes in
T15738 30520-30530 JJ denotes infectious
T15739 30531-30539 NN denotes diseases
T19140 31805-31814 NN denotes Isolation
T19141 31815-31817 IN denotes of
T19142 31818-31822 JJ denotes CD4+
T19143 31823-31824 NN denotes T
T19144 31825-31830 NN denotes Cells
T19145 31831-31834 CC denotes and
T19146 31835-31837 IN denotes of
T19147 31838-31845 JJ denotes Splenic
T19148 31846-31848 NN denotes DC
T19149 31849-31852 CC denotes and
T19150 31853-31857 NNP denotes Cell
T19151 31858-31865 NN denotes Culture
T19152 31866-31869 IN denotes for
T19153 31870-31871 NN denotes T
T19154 31872-31876 NN denotes Cell
T19155 31877-31886 NN denotes Phenotype
T19156 31887-31902 NN denotes Differentiation
T19157 31903-31904 NN denotes T
T19158 31905-31910 NN denotes cells
T19159 31911-31915 VB denotes were
T19160 31916-31922 VB denotes sorted
T19161 31923-31926 IN denotes for
T19162 31927-31938 NN denotes CD4+CD62Lhi
T19163 31938-31939 -COMMA- denotes ,
T19164 31940-31956 NN denotes CD4+CD62LhiCD25−
T19165 31956-31957 -COMMA- denotes ,
T19166 31958-31960 CC denotes or
T19167 31961-31976 NN denotes CD4+CD44loCD25−
T19168 31977-31979 TO denotes to
T19169 31980-31981 SYM denotes >
T19170 31981-31983 CD denotes 98
T19171 31983-31984 NN denotes %
T19172 31985-31987 IN denotes on
T19173 31988-31989 DT denotes a
T19174 31990-31995 NNP denotes Moflo
T19175 31996-32005 NN denotes cytometer
T19176 32006-32007 -LRB- denotes (
T19177 32007-32017 NN denotes Cytomation
T19178 32017-32018 -RRB- denotes )
T19179 32019-32021 IN denotes as
T19180 32022-32028 IN denotes before
T19181 32029-32030 -LRB- denotes (
T19182 32030-32039 NNP denotes Shoemaker
T19183 32040-32046 NNP denotes et al.
T19184 32046-32047 -COMMA- denotes ,
T19185 32048-32052 CD denotes 2006
T19186 32052-32053 -COLON- denotes ;
T19187 32054-32062 NNP denotes Veldhoen
T19188 32063-32069 FW denotes et al.
T19189 32069-32070 -COMMA- denotes ,
T19190 32071-32075 CD denotes 2009
T19191 32075-32076 -RRB- denotes )
T19192 32078-32080 IN denotes In
T19193 32081-32085 JJ denotes most
T19194 32086-32091 NN denotes cases
T19195 32091-32092 -COMMA- denotes ,
T19196 32093-32104 NN denotes experiments
T19197 32105-32109 VB denotes were
T19198 32110-32120 VB denotes reproduced
T19199 32121-32125 IN denotes with
T19200 32126-32130 DT denotes each
T19201 32131-32135 NN denotes type
T19202 32136-32138 IN denotes of
T19203 32139-32147 VB denotes purified
T19204 32148-32152 JJ denotes CD4+
T19205 32153-32159 NN denotes T cell
T19206 32160-32170 NN denotes population
T19207 32171-32175 IN denotes with
T19208 32176-32183 JJ denotes similar
T19209 32184-32191 NN denotes results
T19210 32192-32200 VB denotes obtained
T19211 32202-32209 JJ denotes Splenic
T19212 32210-32213 NN denotes DCs
T19213 32214-32218 VB denotes were
T19214 32219-32227 VB denotes prepared
T19215 32228-32230 IN denotes as
T19216 32231-32240 VB denotes described
T19217 32241-32242 -LRB- denotes (
T19218 32242-32248 NNP denotes Hosken
T19219 32249-32255 NNP denotes et al.
T19220 32255-32256 -COMMA- denotes ,
T19221 32257-32261 CD denotes 1995
T19222 32261-32262 -RRB- denotes )
T19223 32262-32263 -COMMA- denotes ,
T19224 32264-32267 CC denotes and
T19225 32268-32272 NN denotes sort
T19226 32273-32281 VB denotes purified
T19227 32282-32288 JJ denotes CD11c+
T19228 32289-32294 NN denotes cells
T19229 32295-32299 VB denotes were
T19230 32300-32305 VB denotes added
T19231 32306-32308 TO denotes to
T19232 32309-32312 DT denotes the
T19233 32313-32319 NN denotes T cell
T19234 32320-32327 NN denotes culture
T19235 32329-32337 VB denotes Purified
T19236 32338-32345 NN denotes DO11.10
T19237 32346-32350 JJ denotes CD4+
T19238 32351-32358 NN denotes T cells
T19239 32359-32360 -LRB- denotes (
T19240 32360-32361 CD denotes 1
T19241 32362-32363 IN denotes ×
T19242 32364-32367 CD denotes 105
T19243 32368-32376 NN denotes cells/ml
T19244 32376-32377 -RRB- denotes )
T19245 32378-32382 VB denotes were
T19246 32383-32391 VB denotes cultured
T19247 32392-32394 IN denotes as
T19248 32395-32401 IN denotes before
T19249 32402-32403 -LRB- denotes (
T19250 32403-32409 NNP denotes Hosken
T19251 32410-32416 NNP denotes et al.
T19252 32416-32417 -COMMA- denotes ,
T19253 32418-32422 CD denotes 1995
T19254 32422-32423 -RRB- denotes )
T19255 32423-32424 -COMMA- denotes ,
T19256 32425-32427 IN denotes in
T19257 32428-32429 DT denotes a
T19258 32430-32435 JJ denotes total
T19259 32436-32442 NN denotes volume
T19260 32443-32445 IN denotes of
T19261 32446-32447 CD denotes 1
T19262 32448-32450 NN denotes ml
T19263 32451-32456 NN denotes cRPMI
T19264 32457-32463 NN denotes medium
T19265 32464-32466 IN denotes in
T19266 32467-32468 DT denotes a
T19267 32469-32476 JJ denotes 48-well
T19268 32477-32482 NN denotes plate
T19269 32482-32483 -COMMA- denotes ,
T19270 32484-32488 IN denotes with
T19271 32489-32496 JJ denotes splenic
T19272 32497-32500 NN denotes DCs
T19273 32501-32502 -LRB- denotes (
T19274 32502-32503 CD denotes 2
T19275 32504-32505 CC denotes ×
T19276 32506-32509 CD denotes 104
T19277 32510-32518 NN denotes cells/ml
T19278 32518-32519 -RRB- denotes )
T19279 32519-32520 -COMMA- denotes ,
T19280 32521-32524 CC denotes and
T19281 32525-32532 VB denotes varying
T19282 32533-32540 NN denotes amounts
T19283 32541-32543 IN denotes of
T19284 32544-32547 NN denotes OVA
T19285 32548-32551 CC denotes and
T19286 32552-32554 IN denotes of
T19287 32555-32560 NN denotes IL-12
T19288 32562-32577 JJ denotes APC-independent
T19289 32578-32593 NN denotes differentiation
T19290 32594-32596 IN denotes of
T19291 32597-32602 JJ denotes naive
T19292 32603-32607 JJ denotes CD4+
T19293 32608-32615 NN denotes T cells
T19294 32616-32620 IN denotes into
T19295 32621-32624 NN denotes Th1
T19296 32625-32628 CC denotes and
T19297 32629-32632 NN denotes Th2
T19298 32633-32638 NN denotes cells
T19299 32639-32643 VB denotes used
T19300 32644-32655 NN denotes stimulation
T19301 32656-32660 IN denotes with
T19302 32661-32669 JJ denotes anti-CD3
T19303 32670-32673 CC denotes and
T19304 32674-32683 JJ denotes anti-CD28
T19305 32684-32687 CC denotes and
T19306 32688-32699 JJ denotes appropriate
T19307 32700-32708 NN denotes cytokine
T19308 32709-32719 NN denotes conditions
T19309 32719-32720 -COMMA- denotes ,
T19310 32721-32724 CC denotes and
T19311 32725-32732 NN denotes control
T19312 32733-32736 NN denotes Th1
T19313 32737-32740 CC denotes and
T19314 32741-32744 NN denotes Th2
T19315 32745-32750 NN denotes cells
T19316 32751-32755 VB denotes were
T19317 32756-32764 VB denotes cultured
T19318 32765-32767 IN denotes as
T19319 32768-32777 VB denotes described
T19320 32778-32784 IN denotes before
T19321 32785-32786 -LRB- denotes (
T19322 32786-32792 NNP denotes Hosken
T19323 32793-32799 NNP denotes et al.
T19324 32799-32800 -COMMA- denotes ,
T19325 32801-32805 CD denotes 1995
T19326 32805-32806 -COLON- denotes ;
T19327 32807-32816 NNP denotes Shoemaker
T19328 32817-32823 FW denotes et al.
T19329 32823-32824 -COMMA- denotes ,
T19330 32825-32829 CD denotes 2006
T19331 32829-32830 -RRB- denotes )
T19332 32832-32839 NN denotes Culture
T19333 32840-32850 NN denotes conditions
T19334 32851-32854 IN denotes for
T19335 32855-32859 NN denotes Th17
T19336 32860-32865 NN denotes cells
T19337 32866-32870 VB denotes were
T19338 32871-32873 IN denotes as
T19339 32874-32883 VB denotes described
T19340 32884-32890 IN denotes before
T19341 32891-32892 -LRB- denotes (
T19342 32892-32900 NNP denotes Veldhoen
T19343 32901-32907 NNP denotes et al.
T19344 32907-32908 -COMMA- denotes ,
T19345 32909-32913 CD denotes 2006
T19346 32913-32914 -RRB- denotes )
T19347 32916-32927 RB denotes Importantly
T19348 32927-32928 -COMMA- denotes ,
T19349 32929-32932 NN denotes Th1
T19350 32933-32936 CC denotes and
T19351 32937-32940 NN denotes Th2
T19352 32941-32946 NN denotes cells
T19353 32947-32952 MD denotes could
T19354 32953-32955 VB denotes be
T19355 32956-32970 VB denotes differentiated
T19356 32971-32973 IN denotes in
T19357 32974-32979 NN denotes cRPMI
T19358 32980-32982 CC denotes or
T19359 32983-32987 NN denotes IMDM
T19360 32988-32989 -LRB- denotes (
T19361 32989-32995 NNP denotes Hosken
T19362 32996-33002 NNP denotes et al.
T19363 33002-33003 -COMMA- denotes ,
T19364 33004-33008 CD denotes 1995
T19365 33008-33009 -COLON- denotes ;
T19366 33010-33019 NNP denotes Shoemaker
T19367 33020-33026 FW denotes et al.
T19368 33026-33027 -COMMA- denotes ,
T19369 33028-33032 CD denotes 2006
T19370 33032-33033 -COLON- denotes ;
T19371 33034-33042 NNP denotes Veldhoen
T19372 33043-33049 FW denotes et al.
T19373 33049-33050 -COMMA- denotes ,
T19374 33051-33055 CD denotes 2006
T19375 33055-33056 -RRB- denotes )
T19376 33056-33057 -COMMA- denotes ,
T19377 33058-33061 CC denotes but
T19378 33062-33066 NN denotes Th17
T19379 33067-33072 NN denotes cells
T19380 33073-33077 VB denotes were
T19381 33078-33082 RB denotes only
T19382 33083-33097 VB denotes differentiated
T19383 33098-33107 RB denotes optimally
T19384 33108-33110 IN denotes in
T19385 33111-33115 NNP denotes IMDM
T19386 33116-33117 -LRB- denotes (
T19387 33117-33125 NNP denotes Veldhoen
T19388 33126-33132 NNP denotes et al.
T19389 33132-33133 -COMMA- denotes ,
T19390 33134-33138 CD denotes 2009
T19391 33138-33139 -RRB- denotes )
T19392 33141-33145 WRB denotes When
T19393 33146-33155 VB denotes indicated
T19394 33155-33156 -COMMA- denotes ,
T19395 33157-33162 NN denotes U0126
T19396 33163-33165 CC denotes or
T19397 33166-33174 NN denotes PD184352
T19398 33175-33176 -LRB- denotes (
T19399 33176-33179 NN denotes MEK
T19400 33180-33190 NN denotes inhibitors
T19401 33190-33191 -RRB- denotes )
T19402 33191-33192 -COMMA- denotes ,
T19403 33193-33201 NN denotes SB203580
T19404 33202-33203 -LRB- denotes (
T19405 33203-33206 NN denotes p38
T19406 33207-33216 NN denotes inhibitor
T19407 33216-33217 -RRB- denotes )
T19408 33217-33218 -COMMA- denotes ,
T19409 33219-33226 NN denotes CT99021
T19410 33227-33228 -LRB- denotes (
T19411 33228-33233 NN denotes GSK3β
T19412 33234-33243 NN denotes inhibitor
T19413 33243-33244 -RRB- denotes )
T19414 33244-33245 -COMMA- denotes ,
T19415 33246-33248 CC denotes or
T19416 33249-33250 DT denotes a
T19417 33251-33258 JJ denotes similar
T19418 33259-33265 NN denotes amount
T19419 33266-33268 IN denotes of
T19420 33269-33273 NN denotes DMSO
T19421 33274-33278 VB denotes were
T19422 33279-33286 JJ denotes present
T19423 33287-33289 IN denotes in
T19424 33290-33293 DT denotes the
T19425 33294-33301 NN denotes culture
T19426 33303-33307 JJ denotes More
T19427 33308-33315 NN denotes details
T19428 33316-33318 IN denotes of
T19429 33319-33327 JJ denotes specific
T19430 33328-33335 NN denotes culture
T19431 33336-33346 NN denotes conditions
T19432 33347-33350 VB denotes are
T19433 33351-33359 VB denotes provided
T19434 33360-33362 IN denotes in
T19435 33363-33370 NN denotes Figures
T19436 33371-33373 NN denotes S6
T19437 33374-33377 CC denotes and
T19438 33378-33380 NN denotes S7
T19943 33383-33391 NN denotes Cytokine
T19944 33392-33401 NN denotes Detection
T19945 33402-33404 IN denotes by
T19946 33405-33408 NN denotes ICS
T19947 33409-33412 CC denotes and
T19948 33413-33418 NN denotes ELISA
T19949 33419-33421 IN denotes At
T19950 33422-33425 NN denotes day
T19951 33426-33427 CD denotes 5
T19952 33428-33430 CC denotes or
T19953 33431-33432 CD denotes 7
T19954 33432-33433 -COMMA- denotes ,
T19955 33434-33439 NN denotes cells
T19956 33440-33444 VB denotes were
T19957 33445-33457 VB denotes restimulated
T19958 33458-33462 IN denotes with
T19959 33463-33474 VB denotes immobilized
T19960 33475-33483 NN denotes anti-CD3
T19961 33484-33485 -LRB- denotes (
T19962 33485-33486 CD denotes 2
T19963 33487-33492 NN denotes μg/ml
T19964 33492-33493 -RRB- denotes )
T19965 33494-33497 CC denotes and
T19966 33498-33507 JJ denotes anti-CD28
T19967 33508-33509 -LRB- denotes (
T19968 33509-33510 CD denotes 2
T19969 33511-33516 NN denotes μg/ml
T19970 33516-33517 -RRB- denotes )
T19971 33518-33519 -LRB- denotes (
T19972 33519-33520 CD denotes 4
T19973 33521-33523 NN denotes hr
T19974 33524-33528 IN denotes with
T19975 33529-33539 NNP denotes BrefeldinA
T19976 33540-33541 -LRB- denotes [
T19977 33541-33543 CD denotes 10
T19978 33544-33549 NN denotes μg/ml
T19979 33549-33550 -RRB- denotes ]
T19980 33551-33553 IN denotes in
T19981 33554-33557 DT denotes the
T19982 33558-33562 JJ denotes last
T19983 33563-33564 CD denotes 2
T19984 33565-33567 NN denotes hr
T19985 33567-33568 -RRB- denotes )
T19986 33569-33571 CC denotes or
T19987 33572-33576 IN denotes with
T19988 33577-33581 NN denotes PdBU
T19989 33582-33585 CC denotes and
T19990 33586-33595 NN denotes Ionomycin
T19991 33596-33597 -LRB- denotes (
T19992 33597-33598 CD denotes 5
T19993 33599-33601 NN denotes hr
T19994 33602-33606 IN denotes with
T19995 33607-33617 NNP denotes BrefeldinA
T19996 33618-33619 -LRB- denotes [
T19997 33619-33620 CD denotes 1
T19998 33621-33626 NN denotes μg/ml
T19999 33626-33627 -RRB- denotes ]
T20000 33627-33628 -RRB- denotes )
T20001 33630-33635 IN denotes After
T20002 33636-33639 NNP denotes ICS
T20003 33640-33644 NNP denotes FACS
T20004 33644-33645 -COMMA- denotes ,
T20005 33646-33650 NN denotes data
T20006 33651-33655 VB denotes were
T20007 33656-33665 VB denotes collected
T20008 33666-33668 IN denotes on
T20009 33669-33670 DT denotes a
T20010 33671-33682 NNP denotes FACSCalibur
T20011 33683-33684 -LRB- denotes (
T20012 33684-33690 NNP denotes Becton
T20013 33691-33700 NNP denotes Dickinson
T20014 33700-33701 -RRB- denotes )
T20015 33702-33705 CC denotes and
T20016 33706-33714 VB denotes analyzed
T20017 33715-33719 IN denotes with
T20018 33720-33726 NNP denotes FlowJo
T20019 33727-33728 -LRB- denotes (
T20020 33728-33732 NNP denotes Tree
T20021 33733-33737 NNP denotes Star
T20022 33737-33738 -RRB- denotes )
T20023 33740-33743 IN denotes For
T20024 33744-33749 NN denotes ELISA
T20025 33749-33750 -COMMA- denotes ,
T20026 33751-33756 NN denotes cells
T20027 33757-33761 VB denotes were
T20028 33762-33771 RB denotes similarly
T20029 33772-33784 VB denotes restimulated
T20030 33785-33788 IN denotes for
T20031 33789-33791 CD denotes 48
T20032 33792-33794 NN denotes hr
T20033 33795-33798 CC denotes and
T20034 33799-33810 NN denotes supernatant
T20035 33811-33814 VB denotes was
T20036 33815-33824 VB denotes collected
T20037 33825-33828 CC denotes and
T20038 33829-33837 VB denotes analyzed
T20039 33838-33841 IN denotes for
T20040 33842-33846 NN denotes IL-4
T20041 33846-33847 -COMMA- denotes ,
T20042 33848-33853 NN denotes IL-10
T20043 33853-33854 -COMMA- denotes ,
T20044 33855-33858 CC denotes and
T20045 33859-33864 NN denotes IFN-γ
T20046 33865-33867 IN denotes as
T20047 33868-33877 VB denotes described
T20048 33878-33884 IN denotes before
T20049 33885-33886 -LRB- denotes (
T20050 33886-33895 NNP denotes Shoemaker
T20051 33896-33902 NNP denotes et al.
T20052 33902-33903 -COMMA- denotes ,
T20053 33904-33908 CD denotes 2006
T20054 33908-33909 -RRB- denotes )
T20251 33912-33914 IN denotes In
T20252 33915-33919 NNP denotes Vivo
T20253 33920-33927 NN denotes Studies
T20254 33928-33934 NN denotes BALB/c
T20255 33935-33939 NN denotes mice
T20256 33940-33944 VB denotes were
T20257 33945-33953 VB denotes injected
T20258 33954-33967 RB denotes intravenously
T20259 33968-33969 -LRB- denotes (
T20260 33969-33973 RB denotes i.v.
T20261 33973-33974 -RRB- denotes )
T20262 33975-33979 IN denotes with
T20263 33980-33981 DT denotes a
T20264 33982-33985 JJ denotes red
T20265 33986-33991 NN denotes blood
T20266 33992-34005 JJ denotes cell-depleted
T20267 34006-34017 JJ denotes single-cell
T20268 34018-34024 NN denotes spleen
T20269 34025-34035 NN denotes suspension
T20270 34036-34037 -LRB- denotes (
T20271 34037-34040 CD denotes 2.5
T20272 34041-34042 CC denotes ×
T20273 34043-34046 CD denotes 107
T20274 34047-34052 NN denotes cells
T20275 34052-34053 -RRB- denotes )
T20276 34054-34055 -LRB- denotes (
T20277 34055-34061 NNP denotes Castro
T20278 34062-34068 NNP denotes et al.
T20279 34068-34069 -COMMA- denotes ,
T20280 34070-34074 CD denotes 2000
T20281 34074-34075 -RRB- denotes )
T20282 34076-34080 IN denotes from
T20283 34081-34088 NN denotes DO11.10
T20284 34089-34091 NN denotes WT
T20285 34092-34094 CC denotes or
T20286 34095-34109 JJ denotes STAT-deficient
T20287 34110-34114 NN denotes mice
T20288 34116-34121 IN denotes After
T20289 34122-34124 CD denotes 48
T20290 34125-34127 NN denotes hr
T20291 34127-34128 -COMMA- denotes ,
T20292 34129-34133 PRP denotes they
T20293 34134-34138 VB denotes were
T20294 34139-34147 VB denotes injected
T20295 34148-34162 RB denotes subcutaneously
T20296 34163-34167 IN denotes with
T20297 34168-34171 NN denotes PBS
T20298 34172-34174 CC denotes or
T20299 34175-34179 IN denotes with
T20300 34180-34183 NN denotes OVA
T20301 34184-34191 NN denotes protein
T20302 34192-34193 -LRB- denotes (
T20303 34193-34194 CD denotes 5
T20304 34195-34197 NN denotes mg
T20305 34197-34198 -RRB- denotes )
T20306 34199-34203 CC denotes plus
T20307 34204-34207 NN denotes LPS
T20308 34208-34209 -LRB- denotes (
T20309 34209-34210 CD denotes 5
T20310 34211-34213 NN denotes μg
T20311 34213-34214 -RRB- denotes )
T20312 34216-34219 DT denotes The
T20313 34220-34228 JJ denotes inguinal
T20314 34229-34234 NN denotes lymph
T20315 34235-34240 NN denotes nodes
T20316 34241-34245 VB denotes were
T20317 34246-34253 VB denotes removed
T20318 34254-34256 CD denotes 48
T20319 34257-34259 NN denotes hr
T20320 34260-34265 RB denotes later
T20321 34267-34268 DT denotes A
T20322 34269-34280 JJ denotes single-cell
T20323 34281-34291 NN denotes suspension
T20324 34292-34293 -LRB- denotes (
T20325 34293-34294 CD denotes 1
T20326 34295-34296 NN denotes ×
T20327 34297-34300 CD denotes 106
T20328 34301-34306 NN denotes cells
T20329 34306-34307 -RRB- denotes )
T20330 34308-34311 VB denotes was
T20331 34312-34324 VB denotes restimulated
T20332 34325-34328 IN denotes for
T20333 34329-34331 CD denotes 24
T20334 34332-34334 CC denotes or
T20335 34335-34337 CD denotes 48
T20336 34338-34340 NN denotes hr
T20337 34341-34345 IN denotes with
T20338 34346-34347 CD denotes 1
T20339 34348-34350 NN denotes μM
T20340 34351-34353 CC denotes or
T20341 34354-34355 CD denotes 3
T20342 34356-34358 NN denotes μM
T20343 34359-34361 IN denotes of
T20344 34362-34365 NN denotes OVA
T20345 34366-34369 CC denotes and
T20346 34370-34374 IN denotes with
T20347 34375-34385 NNP denotes BrefeldinA
T20348 34386-34389 IN denotes for
T20349 34390-34393 DT denotes the
T20350 34394-34398 JJ denotes last
T20351 34399-34400 CD denotes 6
T20352 34401-34403 NN denotes hr
T20353 34405-34409 NN denotes Half
T20354 34410-34412 IN denotes of
T20355 34413-34416 DT denotes the
T20356 34417-34428 NN denotes supernatant
T20357 34429-34432 VB denotes was
T20358 34433-34440 VB denotes removed
T20359 34441-34447 IN denotes before
T20360 34448-34451 DT denotes the
T20361 34452-34460 NN denotes addition
T20362 34461-34463 IN denotes of
T20363 34464-34474 NNP denotes BrefeldinA
T20364 34475-34478 IN denotes for
T20365 34479-34482 NN denotes use
T20366 34483-34485 IN denotes in
T20367 34486-34488 DT denotes an
T20368 34489-34494 NN denotes ELISA
T20369 34495-34500 NN denotes assay
T20370 34502-34505 DT denotes The
T20371 34506-34511 NN denotes cells
T20372 34512-34516 VB denotes were
T20373 34517-34522 VB denotes fixed
T20374 34523-34526 CC denotes and
T20375 34527-34534 VB denotes stained
T20376 34535-34537 IN denotes as
T20377 34538-34544 RB denotes before
T20378 34546-34551 DT denotes Those
T20379 34552-34560 JJ denotes positive
T20380 34561-34564 IN denotes for
T20381 34565-34575 NN denotes KJ1-26-Bio
T20382 34576-34579 CC denotes and
T20383 34580-34583 IN denotes for
T20384 34584-34593 NN denotes CD4-PerCP
T20385 34594-34598 VB denotes were
T20386 34599-34604 VB denotes gated
T20387 34604-34605 -COMMA- denotes ,
T20388 34606-34609 CC denotes and
T20389 34610-34615 NN denotes IFN-γ
T20390 34616-34619 CC denotes and
T20391 34620-34625 NN denotes IL-10
T20392 34626-34634 NN denotes staining
T20393 34635-34638 VB denotes was
T20394 34639-34647 VB denotes examined
T20395 34648-34651 IN denotes for
T20396 34652-34656 DT denotes this
T20397 34657-34667 NN denotes population
T20398 34668-34671 CC denotes and
T20399 34672-34680 VB denotes analyzed
T20400 34681-34683 IN denotes as
T20401 34684-34690 RB denotes before
T20634 34693-34702 JJ denotes Real-Time
T20635 34703-34715 JJ denotes Quantitative
T20636 34716-34722 NN denotes RT-PCR
T20637 34723-34728 NN denotes Cells
T20638 34729-34733 VB denotes were
T20639 34734-34743 VB denotes harvested
T20640 34744-34747 CC denotes and
T20641 34748-34760 VB denotes restimulated
T20642 34761-34763 IN denotes in
T20643 34764-34767 DT denotes the
T20644 34768-34776 NN denotes presence
T20645 34777-34779 IN denotes of
T20646 34780-34791 VB denotes immobilized
T20647 34792-34800 NN denotes anti-CD3
T20648 34801-34802 -LRB- denotes (
T20649 34802-34803 CD denotes 2
T20650 34804-34809 NN denotes μg/ml
T20651 34809-34810 -RRB- denotes )
T20652 34811-34815 CC denotes plus
T20653 34816-34825 NN denotes anti-CD28
T20654 34826-34827 -LRB- denotes (
T20655 34827-34828 CD denotes 2
T20656 34829-34834 NN denotes μg/ml
T20657 34834-34835 -RRB- denotes )
T20658 34836-34839 IN denotes for
T20659 34840-34841 CD denotes 3
T20660 34842-34844 NN denotes hr
T20661 34845-34847 CC denotes or
T20662 34848-34859 RB denotes immediately
T20663 34860-34865 VB denotes lysed
T20664 34867-34870 NN denotes RNA
T20665 34871-34874 VB denotes was
T20666 34875-34884 VB denotes extracted
T20667 34885-34888 CC denotes and
T20668 34889-34908 JJ denotes reverse-transcribed
T20669 34909-34912 CC denotes and
T20670 34913-34917 NN denotes cDNA
T20671 34918-34921 VB denotes was
T20672 34922-34930 VB denotes analyzed
T20673 34931-34934 IN denotes for
T20674 34935-34938 DT denotes the
T20675 34939-34949 NN denotes expression
T20676 34950-34952 IN denotes of
T20677 34953-34962 NN denotes cytokines
T20678 34963-34966 CC denotes and
T20679 34967-34980 NN denotes transcription
T20680 34981-34988 NN denotes factors
T20681 34989-34991 IN denotes by
T20682 34992-35001 JJ denotes real-time
T20683 35002-35005 NN denotes PCR
T20684 35006-35011 NN denotes assay
T20685 35012-35014 IN denotes as
T20686 35015-35021 IN denotes before
T20687 35022-35023 -LRB- denotes (
T20688 35023-35032 NNP denotes Shoemaker
T20689 35033-35039 NNP denotes et al.
T20690 35039-35040 -COMMA- denotes ,
T20691 35041-35045 CD denotes 2006
T20692 35045-35046 -RRB- denotes )
T20693 35048-35054 NN denotes Target
T20694 35055-35059 NN denotes gene
T20695 35060-35064 NN denotes mRNA
T20696 35065-35075 NN denotes expression
T20697 35076-35079 VB denotes was
T20698 35080-35090 VB denotes quantified
T20699 35091-35097 CC denotes either
T20700 35098-35102 IN denotes with
T20701 35103-35107 NN denotes SYBR
T20702 35108-35113 NNP denotes Green
T20703 35114-35115 -LRB- denotes (
T20704 35115-35122 NNP denotes Applied
T20705 35123-35133 NNP denotes Biosystems
T20706 35133-35134 -RRB- denotes )
T20707 35135-35137 CC denotes or
T20708 35138-35142 IN denotes with
T20709 35143-35149 NNP denotes Master
T20710 35150-35153 NNP denotes Mix
T20711 35154-35155 -LRB- denotes (
T20712 35155-35162 NNP denotes Applied
T20713 35163-35173 NNP denotes Biosystems
T20714 35173-35174 -RRB- denotes )
T20715 35175-35178 CC denotes and
T20716 35179-35189 VB denotes normalized
T20717 35190-35192 TO denotes to
T20718 35193-35202 NN denotes ubiquitin
T20719 35203-35205 CC denotes or
T20720 35206-35210 NN denotes HPRT
T20721 35211-35215 NN denotes mRNA
T20722 35216-35222 NN denotes levels
T20723 35222-35223 -COMMA- denotes ,
T20724 35224-35236 RB denotes respectively
T20871 35239-35253 NN denotes Immunoblotting
T20872 35254-35268 VB denotes Differentiated
T20873 35269-35273 JJ denotes CD4+
T20874 35274-35281 NN denotes T cells
T20875 35282-35286 VB denotes were
T20876 35287-35293 VB denotes rested
T20877 35294-35297 IN denotes for
T20878 35298-35299 CD denotes 5
T20879 35300-35302 NN denotes hr
T20880 35303-35305 IN denotes in
T20881 35306-35307 CD denotes 1
T20882 35307-35308 NN denotes %
T20883 35309-35323 JJ denotes FCS-containing
T20884 35324-35330 NN denotes medium
T20885 35331-35334 CC denotes and
T20886 35335-35347 VB denotes restimulated
T20887 35348-35350 IN denotes as
T20888 35351-35360 VB denotes described
T20889 35361-35364 IN denotes for
T20890 35365-35373 JJ denotes specific
T20891 35374-35385 NN denotes experiments
T20892 35387-35391 NN denotes Cell
T20893 35392-35399 NN denotes lysates
T20894 35400-35404 VB denotes were
T20895 35405-35413 VB denotes prepared
T20896 35413-35414 -COMMA- denotes ,
T20897 35415-35420 JJ denotes equal
T20898 35421-35428 NN denotes amounts
T20899 35429-35431 IN denotes of
T20900 35432-35439 NN denotes protein
T20901 35440-35444 VB denotes were
T20902 35445-35454 VB denotes separated
T20903 35455-35457 IN denotes by
T20904 35458-35466 NN denotes SDS-PAGE
T20905 35466-35467 -COMMA- denotes ,
T20906 35468-35471 CC denotes and
T20907 35472-35486 VB denotes phosphorylated
T20908 35487-35489 CC denotes or
T20909 35490-35495 JJ denotes total
T20910 35496-35499 NN denotes ERK
T20911 35500-35503 CC denotes and
T20912 35504-35509 NN denotes actin
T20913 35510-35514 VB denotes were
T20914 35515-35523 VB denotes detected
T20915 35524-35526 IN denotes as
T20916 35527-35536 VB denotes described
T20917 35537-35543 IN denotes before
T20918 35544-35545 -LRB- denotes (
T20919 35545-35551 NNP denotes Beinke
T20920 35552-35558 NNP denotes et al.
T20921 35558-35559 -COMMA- denotes ,
T20922 35560-35564 CD denotes 2004
T20923 35564-35565 -RRB- denotes )
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R107 T198 T197 arg1Of development,the
R108 T198 T199 arg1Of development,of
R109 T205 T204 arg2Of Th1,(
R10993 T14234 T14233 arg1Of expression,IL-10
R10994 T14234 T14235 arg1Of expression,by
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R10996 T14236 T14235 arg2Of cells,by
R10997 T14236 T14237 arg1Of cells,of
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R110 T206 T204 arg3Of ),(
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R11001 T14243 T14238 arg1Of systems,the
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R11005 T14244 T14258 arg1Of reflects,","
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R11007 T14246 T14244 arg2Of importance,reflects
R11008 T14246 T14245 arg1Of importance,the
R11009 T14246 T14247 arg1Of importance,of
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R11011 T14249 T14248 arg1Of cytokine,this
R11012 T14249 T14250 arg1Of cytokine,in
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R11014 T14253 T14251 arg1Of regulation,the
R11015 T14253 T14252 arg1Of regulation,tight
R11016 T14253 T14254 arg1Of regulation,of
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R11033 T14271 T14270 arg2Of reported,been
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R11035 T14273 T14272 arg1Of regulate,to
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R11037 T14276 T14274 arg1Of response,the
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R11039 T14276 T14277 arg1Of response,in
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R11042 T14280 T14279 arg2Of toxoplasmosis,and
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R11044 T14285 T14284 arg1Of situations,many
R11045 T14287 T14288 arg1Of IL-10,is
R11046 T14287 T14290 arg2Of IL-10,produced
R11047 T14290 T14281 arg1Of produced,However
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R11050 T14290 T14286 arg1Of produced,","
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R11052 T14290 T14289 arg1Of produced,not
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R11056 T14293 T14292 arg1Of cells,Th1
R11057 T14295 T14294 arg2Of response,in
R11058 T14295 T14296 arg1Of response,to
R11059 T14298 T14296 arg2Of stimulation,to
R11060 T14298 T14297 arg1Of stimulation,antigenic
R11061 T14300 T14299 arg1Of goal,Our
R11062 T14300 T14301 arg1Of goal,was
R11063 T14303 T14301 arg2Of address,was
R11064 T14303 T14302 arg1Of address,to
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R11066 T14306 T14304 arg1Of signals,the
R11067 T14306 T14305 arg1Of signals,molecular
R11068 T14306 T14307 arg1Of signals,that
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R11071 T14311 T14312 arg1Of cells,develop
R11072 T14311 T14314 arg1Of cells,produce
R11073 T14312 T14308 arg2Of develop,determine
R11074 T14312 T14309 arg1Of develop,whether
R11075 T14312 T14313 modOf develop,to
R11076 T14312 T14316 arg1Of develop,(
R11077 T14314 T14313 arg1Of produce,to
R11078 T14315 T14314 arg2Of IL-10,produce
R11079 T14317 T14316 arg2Of Trinchieri,(
R11080 T14317 T14318 arg1Of Trinchieri,","
R11081 T14317 T14319 arg1Of Trinchieri,2007
R11082 T14320 T14316 arg3Of ),(
R11083 T14323 T14324 arg1Of we,showed
R11084 T14324 T14321 arg1Of showed,Here
R11085 T14324 T14322 arg1Of showed,","
R11086 T14327 T14326 arg1Of cells,Th1
R11087 T14327 T14328 arg1Of cells,required
R11088 T14328 T14324 arg2Of required,showed
R11089 T14328 T14325 arg1Of required,that
R11090 T14330 T14329 arg1Of ERK1,high-antigen-dose-induced
R11091 T14330 T14331 arg1Of ERK1,and
R11092 T14331 T14334 arg1Of and,and
R11093 T14333 T14331 arg2Of phosphorylation,and
R11094 T14333 T14332 arg1Of phosphorylation,ERK2
R11095 T14334 T14328 arg2Of and,required
R11096 T14337 T14334 arg2Of activation,and
R11097 T14337 T14335 arg1Of activation,IL-12-induced
R11098 T14337 T14336 arg1Of activation,STAT-4
R11099 T14337 T14338 modOf activation,to
R111 T207 T199 arg2Of cells,of
R11100 T14339 T14338 arg1Of produce,to
R11101 T14340 T14339 arg2Of IL-10,produce
R11102 T14342 T14341 arg1Of findings,Our
R11103 T14342 T14352 arg2Of findings,required
R11104 T14342 T14373 arg1Of findings,","
R11105 T14342 T14374 arg1Of findings,such
R11106 T14344 T14345 arg1Of ERK1,and
R11107 T14345 T14348 arg1Of and,was
R11108 T14347 T14345 arg2Of activation,and
R11109 T14347 T14346 arg1Of activation,ERK2
R11110 T14348 T14342 arg2Of was,findings
R11111 T14348 T14343 arg1Of was,that
R11112 T14351 T14348 arg2Of pathway,was
R11113 T14351 T14349 arg1Of pathway,a
R11114 T14351 T14350 arg1Of pathway,common
R11115 T14352 T14353 arg1Of required,for
R11116 T14355 T14353 arg2Of production,for
R11117 T14355 T14354 arg1Of production,the
R11118 T14355 T14356 arg1Of production,of
R11119 T14357 T14356 arg2Of IL-10,of
R11120 T14357 T14358 arg1Of IL-10,by
R11121 T14359 T14360 arg1Of Th1,","
R11122 T14360 T14363 arg1Of ",",and
R11123 T14361 T14360 arg2Of Th2,","
R11124 T14363 T14362 arg1Of and,","
R11125 T14364 T14363 arg2Of Th17,and
R11126 T14366 T14358 arg2Of subsets,by
R11127 T14366 T14359 arg1Of subsets,Th1
R11128 T14366 T14361 arg1Of subsets,Th2
R11129 T14366 T14364 arg1Of subsets,Th17
R11130 T14366 T14365 arg1Of subsets,cell
R11131 T14366 T14367 arg1Of subsets,","
R11132 T14366 T14368 arg1Of subsets,which
R11133 T14366 T14369 arg1Of subsets,differentiate
R11134 T14369 T14370 arg1Of differentiate,along
R11135 T14372 T14370 arg2Of pathways,along
R11136 T14372 T14371 arg1Of pathways,distinct
R11137 T14376 T14377 arg1Of IL-10,provides
R11138 T14376 T14384 arg1Of IL-10,avoid
R11139 T14376 T14395 arg1Of IL-10,allow
R11140 T14377 T14383 modOf provides,to
R11141 T14377 T14393 arg1Of provides,and
R11142 T14380 T14379 arg1Of regulated,highly
R11143 T14382 T14377 arg2Of loop,provides
R11144 T14382 T14378 arg1Of loop,a
R11145 T14382 T14380 arg1Of loop,regulated
R11146 T14382 T14381 arg1Of loop,feedback
R11147 T14384 T14383 arg1Of avoid,to
R11148 T14386 T14384 arg2Of extremes,avoid
R11149 T14386 T14385 arg1Of extremes,the
R11150 T14386 T14387 arg1Of extremes,of
R11151 T14389 T14388 arg1Of inflammation,excessive
R11152 T14389 T14390 arg1Of inflammation,or
R11153 T14390 T14387 arg2Of or,of
R11154 T14392 T14390 arg2Of infections,or
R11155 T14392 T14391 arg1Of infections,chronic
R11156 T14393 T14374 arg2Of and,such
R11157 T14393 T14375 arg1Of and,that
R11158 T14395 T14393 arg2Of allow,and
R11159 T14395 T14394 arg1Of allow,also
R11160 T14398 T14395 arg2Of response,allow
R11161 T14398 T14396 arg1Of response,a
R11162 T14398 T14397 arg1Of response,protective
R11163 T14398 T14399 arg1Of response,to
R11164 T14401 T14399 arg2Of pathogens,to
R11165 T14401 T14400 arg1Of pathogens,diverse
R11166 T14404 T14405 arg1Of viral,or
R11167 T14406 T14405 arg2Of parasitic,or
R11168 T14407 T14402 arg2Of infections,In
R11169 T14407 T14403 arg1Of infections,certain
R11170 T14407 T14404 arg1Of infections,viral
R11171 T14407 T14406 arg1Of infections,parasitic
R11172 T14407 T14408 arg1Of infections,(
R11173 T14410 T14409 arg1Of et al.,Anderson
R11174 T14410 T14411 arg1Of et al.,","
R11175 T14410 T14413 arg1Of et al.,;
R11176 T14412 T14411 arg2Of 2007,","
R11177 T14413 T14418 arg1Of ;,;
R11178 T14414 T14413 arg2Of Brooks,;
R11179 T14414 T14415 arg1Of Brooks,et al.
R11180 T14414 T14416 arg1Of Brooks,","
R11181 T14417 T14416 arg2Of 2006,","
R11182 T14418 T14408 arg2Of ;,(
R11183 T14420 T14418 arg2Of et al.,;
R11184 T14420 T14419 arg1Of et al.,Ejrnaes
R11185 T14420 T14421 arg1Of et al.,","
R11186 T14422 T14421 arg2Of 2006,","
R11187 T14423 T14408 arg3Of ),(
R11188 T14426 T14425 arg1Of amounts,high
R11189 T14426 T14427 arg1Of amounts,of
R11190 T14426 T14429 arg1Of amounts,may
R11191 T14426 T14430 arg1Of amounts,lead
R11192 T14428 T14427 arg2Of stimulation,of
R11193 T14430 T14402 arg1Of lead,In
R11194 T14430 T14424 arg1Of lead,","
R11195 T14430 T14429 arg2Of lead,may
R11196 T14430 T14431 arg1Of lead,to
R11197 T14434 T14433 arg1Of nonhealing,chronic
R11198 T14435 T14431 arg2Of infection,to
R11199 T14435 T14432 arg1Of infection,the
R112 T207 T200 arg1Of cells,IL-10-producing
R11200 T14435 T14434 arg1Of infection,nonhealing
R11201 T14435 T14436 arg2Of infection,shown
R11202 T14435 T14438 arg1Of infection,be
R11203 T14435 T14439 arg2Of infection,regulated
R11204 T14439 T14436 arg3Of regulated,shown
R11205 T14439 T14437 arg1Of regulated,to
R11206 T14439 T14438 arg2Of regulated,be
R11207 T14441 T14439 arg1Of IL-10,regulated
R11208 T14441 T14440 arg2Of IL-10,by
R11209 T14444 T14442 arg2Of course,During
R11210 T14444 T14443 arg1Of course,the
R11211 T14444 T14445 arg1Of course,of
R11212 T14446 T14445 arg2Of infection,of
R11213 T14450 T14448 arg2Of triggering,after
R11214 T14450 T14449 arg1Of triggering,initial
R11215 T14450 T14451 arg1Of triggering,with
R11216 T14452 T14451 arg2Of antigen,with
R11217 T14454 T14455 arg1Of T cells,migrate
R11218 T14455 T14442 arg1Of migrate,During
R11219 T14455 T14447 arg1Of migrate,","
R11220 T14455 T14448 arg1Of migrate,after
R11221 T14455 T14453 arg1Of migrate,","
R11222 T14455 T14456 arg1Of migrate,to
R11223 T14458 T14456 arg2Of tissue,to
R11224 T14458 T14457 arg1Of tissue,the
R11225 T14458 T14459 arg1Of tissue,encountering
R11226 T14461 T14460 arg1Of doses,high
R11227 T14461 T14462 arg1Of doses,of
R11228 T14461 T14464 arg1Of doses,and
R11229 T14463 T14462 arg2Of antigen,of
R11230 T14464 T14459 arg2Of and,encountering
R11231 T14465 T14464 arg2Of factors,and
R11232 T14465 T14466 arg2Of factors,produced
R11233 T14471 T14466 arg1Of response,produced
R11234 T14471 T14467 arg2Of response,by
R11235 T14471 T14468 arg1Of response,the
R11236 T14471 T14469 arg1Of response,innate
R11237 T14471 T14470 arg1Of response,immune
R11238 T14474 T14472 arg2Of conditions,Under
R11239 T14474 T14473 arg1Of conditions,these
R11240 T14476 T14477 arg1Of we,speculate
R11241 T14477 T14472 arg1Of speculate,Under
R11242 T14477 T14475 arg1Of speculate,","
R11243 T14480 T14479 arg1Of cells,Th1
R11244 T14480 T14481 arg1Of cells,will
R11245 T14480 T14482 arg1Of cells,be
R11246 T14480 T14483 arg2Of cells,induced
R11247 T14480 T14485 arg1Of cells,express
R11248 T14483 T14477 arg2Of induced,speculate
R11249 T14483 T14478 arg1Of induced,that
R11250 T14483 T14481 arg2Of induced,will
R11251 T14483 T14482 arg2Of induced,be
R11252 T14485 T14483 arg3Of express,induced
R11253 T14485 T14484 arg1Of express,to
R11254 T14485 T14490 arg1Of express,","
R11255 T14485 T14491 arg1Of express,in
R11256 T14487 T14485 arg2Of amounts,express
R11257 T14487 T14486 arg1Of amounts,high
R11258 T14487 T14488 arg1Of amounts,of
R11259 T14489 T14488 arg2Of IL-10,of
R11260 T14492 T14491 arg2Of keeping,in
R11261 T14492 T14493 arg1Of keeping,with
R11262 T14494 T14507 arg1Of reports,but
R11263 T14498 T14496 arg1Of cells,IL-10-producing
R11264 T14498 T14497 arg1Of cells,Th1
R11265 T14498 T14499 arg1Of cells,were
R11266 T14498 T14500 arg2Of cells,found
R11267 T14500 T14494 arg2Of found,reports
R11268 T14500 T14495 arg1Of found,that
R11269 T14500 T14499 arg2Of found,were
R11270 T14500 T14501 arg1Of found,in
R11271 T14503 T14501 arg2Of clones,in
R11272 T14503 T14502 arg1Of clones,CD4+
R11273 T14503 T14504 arg2Of clones,isolated
R11274 T14504 T14505 arg1Of isolated,from
R11275 T14506 T14505 arg2Of BAL,from
R11276 T14507 T14493 arg2Of but,with
R11277 T14507 T14508 arg1Of but,not
R11278 T14509 T14507 arg2Of blood,but
R11279 T14509 T14510 arg1Of blood,of
R11280 T14509 T14513 arg1Of blood,(
R11281 T14512 T14510 arg2Of patients,of
R11282 T14512 T14511 arg1Of patients,TB
R11283 T14515 T14513 arg2Of et al.,(
R11284 T14515 T14514 arg1Of et al.,Gerosa
R11285 T14515 T14516 arg1Of et al.,","
R11286 T14517 T14516 arg2Of 1999,","
R11287 T14518 T14513 arg3Of ),(
R11288 T14523 T14521 arg1Of response,the
R11289 T14523 T14522 arg1Of response,immune
R11290 T14523 T14524 arg1Of response,to
R11291 T14523 T14531 arg1Of response,","
R11292 T14523 T14532 arg1Of response,which
R11293 T14523 T14533 arg1Of response,produces
R11294 T14523 T14539 arg1Of response,was
R11295 T14523 T14540 arg2Of response,found
R11296 T14523 T14542 arg1Of response,be
R11297 T14523 T14543 arg2Of response,regulated
R11298 T14527 T14524 arg2Of isolate,to
R11299 T14527 T14525 arg1Of isolate,a
R113 T207 T201 arg1Of cells,T
R11300 T14527 T14526 arg1Of isolate,clinical
R11301 T14527 T14528 arg1Of isolate,of
R11302 T14529 T14528 arg2Of L.,of
R11303 T14529 T14530 arg1Of L.,major
R11304 T14535 T14534 arg1Of infected,heavily
R11305 T14537 T14533 arg2Of lesions,produces
R11306 T14537 T14535 arg1Of lesions,infected
R11307 T14537 T14536 arg1Of lesions,nonhealing
R11308 T14540 T14538 arg1Of found,","
R11309 T14540 T14539 arg2Of found,was
R11310 T14540 T14563 arg1Of found,and
R11311 T14543 T14540 arg3Of regulated,found
R11312 T14543 T14541 arg1Of regulated,to
R11313 T14543 T14542 arg2Of regulated,be
R11314 T14545 T14543 arg1Of IL-10,regulated
R11315 T14545 T14544 arg2Of IL-10,by
R11316 T14545 T14546 arg2Of IL-10,derived
R11317 T14546 T14547 arg1Of derived,from
R11318 T14550 T14547 arg2Of cells,from
R11319 T14550 T14548 arg1Of cells,Foxp3−
R11320 T14550 T14549 arg1Of cells,Th1
R11321 T14550 T14551 arg1Of cells,that
R11322 T14550 T14552 arg1Of cells,coproduce
R11323 T14553 T14554 arg1Of IL-10,and
R11324 T14554 T14552 arg2Of and,coproduce
R11325 T14554 T14556 arg1Of and,(
R11326 T14555 T14554 arg2Of IFN-γ,and
R11327 T14558 T14556 arg2Of et al.,(
R11328 T14558 T14557 arg1Of et al.,Anderson
R11329 T14558 T14559 arg1Of et al.,","
R11330 T14560 T14559 arg2Of 2007,","
R11331 T14561 T14556 arg3Of ),(
R11332 T14563 T14519 arg1Of and,Similarly
R11333 T14563 T14520 arg1Of and,","
R11334 T14563 T14562 arg1Of and,","
R11335 T14566 T14564 arg1Of response,the
R11336 T14566 T14565 arg1Of response,immune
R11337 T14566 T14567 arg1Of response,during
R11338 T14566 T14571 arg1Of response,was
R11339 T14566 T14572 arg2Of response,found
R11340 T14566 T14575 arg1Of response,be
R11341 T14566 T14576 arg2Of response,regulated
R11342 T14570 T14567 arg2Of infection,during
R11343 T14570 T14568 arg1Of infection,T.
R11344 T14570 T14569 arg1Of infection,gondii
R11345 T14572 T14563 arg2Of found,and
R11346 T14572 T14571 arg2Of found,was
R11347 T14576 T14572 arg3Of regulated,found
R11348 T14576 T14573 arg1Of regulated,also
R11349 T14576 T14574 arg1Of regulated,to
R11350 T14576 T14575 arg2Of regulated,be
R11351 T14580 T14576 arg1Of cells,regulated
R11352 T14580 T14577 arg2Of cells,by
R11353 T14580 T14578 arg1Of cells,Foxp3−
R11354 T14580 T14579 arg1Of cells,Th1
R11355 T14580 T14581 arg1Of cells,(
R11356 T14583 T14581 arg2Of et al.,(
R11357 T14583 T14582 arg1Of et al.,Jankovic
R11358 T14583 T14584 arg1Of et al.,","
R11359 T14585 T14584 arg2Of 2007,","
R11360 T14586 T14581 arg3Of ),(
R11361 T14587 T14588 arg1Of It,is
R11362 T14587 T14589 arg1Of It,likely
R11363 T14588 T14607 arg1Of is,whereas
R11364 T14589 T14588 arg2Of likely,is
R11365 T14592 T14591 arg1Of production,IL-10
R11366 T14592 T14593 arg1Of production,by
R11367 T14592 T14596 arg1Of production,is
R11368 T14592 T14597 arg2Of production,evoked
R11369 T14595 T14593 arg2Of cells,by
R11370 T14595 T14594 arg1Of cells,Th1
R11371 T14597 T14589 arg2Of evoked,likely
R11372 T14597 T14590 arg1Of evoked,that
R11373 T14597 T14596 arg2Of evoked,is
R11374 T14597 T14598 arg1Of evoked,under
R11375 T14599 T14598 arg2Of conditions,under
R11376 T14599 T14600 arg1Of conditions,of
R11377 T14602 T14601 arg1Of inflammation,high
R11378 T14602 T14603 arg1Of inflammation,and
R11379 T14603 T14600 arg2Of and,of
R11380 T14605 T14603 arg2Of stimulation,and
R11381 T14605 T14604 arg1Of stimulation,antigenic
R11382 T14607 T14606 arg1Of whereas,","
R11383 T14610 T14608 arg1Of T cells,regulatory
R11384 T14610 T14609 arg1Of T cells,CD4+
R11385 T14610 T14611 arg1Of T cells,producing
R11386 T14610 T14613 arg1Of T cells,may
R11387 T14610 T14614 arg1Of T cells,operate
R11388 T14610 T14616 arg1Of T cells,regulate
R11389 T14612 T14611 arg2Of IL-10,producing
R11390 T14614 T14607 arg2Of operate,whereas
R11391 T14614 T14613 arg2Of operate,may
R11392 T14614 T14615 modOf operate,to
R11393 T14616 T14615 arg1Of regulate,to
R11394 T14619 T14616 arg2Of response,regulate
R11395 T14619 T14617 arg1Of response,the
R11396 T14619 T14618 arg1Of response,immune
R11397 T14619 T14620 arg1Of response,under
R11398 T14621 T14620 arg2Of conditions,under
R11399 T14621 T14622 arg2Of conditions,in
R114 T207 T202 arg1Of cells,helper
R11400 T14621 T14623 arg1Of conditions,which
R11401 T14621 T14629 arg1Of conditions,","
R11402 T14621 T14634 arg1Of conditions,with
R11403 T14621 T14641 arg1Of conditions,(
R11404 T14625 T14624 arg1Of pathogen,the
R11405 T14625 T14626 arg1Of pathogen,is
R11406 T14625 T14628 arg2Of pathogen,controlled
R11407 T14628 T14622 arg1Of controlled,in
R11408 T14628 T14626 arg2Of controlled,is
R11409 T14628 T14627 arg1Of controlled,clinically
R11410 T14630 T14632 arg1Of such,in
R11411 T14632 T14631 arg1Of in,as
R11412 T14633 T14632 arg2Of infection,in
R11413 T14634 T14630 arg1Of with,such
R11414 T14636 T14634 arg2Of major,with
R11415 T14636 T14635 arg1Of major,L.
R11416 T14636 T14637 arg1Of major,(
R11417 T14639 T14637 arg2Of strain,(
R11418 T14639 T14638 arg1Of strain,Friedlin
R11419 T14640 T14637 arg3Of ),(
R11420 T14643 T14642 arg1Of et al.,Belkaid
R11421 T14643 T14644 arg1Of et al.,","
R11422 T14643 T14646 arg1Of et al.,;
R11423 T14645 T14644 arg2Of 2002,","
R11424 T14646 T14641 arg2Of ;,(
R11425 T14647 T14646 arg2Of Suffia,;
R11426 T14647 T14648 arg1Of Suffia,et al.
R11427 T14647 T14649 arg1Of Suffia,","
R11428 T14650 T14649 arg2Of 2006,","
R11429 T14651 T14641 arg3Of ),(
R11430 T14652 T14655 arg1Of We,reported
R11431 T14655 T14653 arg1Of reported,now
R11432 T14655 T14654 arg1Of reported,also
R11433 T14658 T14657 arg1Of T cells,CD4+
R11434 T14658 T14659 arg2Of T cells,cultured
R11435 T14658 T14666 arg1Of T cells,differentiate
R11436 T14659 T14660 arg1Of cultured,with
R11437 T14663 T14661 arg1Of dose,high
R11438 T14663 T14662 arg1Of dose,antigen
R11439 T14663 T14664 arg1Of dose,and
R11440 T14664 T14660 arg2Of and,with
R11441 T14665 T14664 arg2Of IL-12,and
R11442 T14666 T14655 arg2Of differentiate,reported
R11443 T14666 T14656 arg1Of differentiate,that
R11444 T14666 T14667 arg1Of differentiate,into
R11445 T14671 T14667 arg2Of cells,into
R11446 T14671 T14668 arg1Of cells,canonical
R11447 T14671 T14669 arg1Of cells,Th1
R11448 T14671 T14670 arg1Of cells,effector
R11449 T14671 T14672 arg1Of cells,","
R11450 T14671 T14673 arg1Of cells,which
R11451 T14671 T14686 arg1Of cells,lose
R11452 T14676 T14675 arg2Of addition,in
R11453 T14676 T14677 arg1Of addition,to
R11454 T14678 T14677 arg2Of expressing,to
R11455 T14680 T14678 arg2Of amounts,expressing
R11456 T14680 T14679 arg1Of amounts,large
R11457 T14680 T14681 arg1Of amounts,of
R11458 T14682 T14683 arg1Of IFN-γ,and
R11459 T14683 T14681 arg2Of and,of
R11460 T14684 T14683 arg2Of IL-10,and
R11461 T14686 T14674 arg1Of lose,","
R11462 T14686 T14675 arg1Of lose,in
R11463 T14686 T14685 arg1Of lose,","
R11464 T14686 T14690 arg1Of lose,as
R11465 T14689 T14686 arg2Of expression,lose
R11466 T14689 T14687 arg1Of expression,their
R11467 T14689 T14688 arg1Of expression,IL-2
R11468 T14691 T14690 arg2Of described,as
R11469 T14691 T14692 arg1Of described,before
R11470 T14691 T14693 arg1Of described,in
R11471 T14697 T14693 arg2Of models,in
R11472 T14697 T14694 arg1Of models,certain
R11473 T14697 T14695 arg1Of models,chronic
R11474 T14697 T14696 arg1Of models,infection
R11475 T14697 T14698 arg1Of models,(
R11476 T14700 T14698 arg2Of et al.,(
R11477 T14700 T14699 arg1Of et al.,Sallusto
R11478 T14700 T14701 arg1Of et al.,","
R11479 T14702 T14701 arg2Of 2004,","
R11480 T14703 T14698 arg3Of ),(
R11481 T14705 T14704 arg1Of demonstration,Our
R11482 T14705 T14716 arg1Of demonstration,offers
R11483 T14707 T14708 arg1Of loss,of
R11484 T14707 T14710 arg1Of loss,is
R11485 T14707 T14711 arg2Of loss,accompanied
R11486 T14709 T14708 arg2Of IL-2,of
R11487 T14711 T14705 arg2Of accompanied,demonstration
R11488 T14711 T14706 arg1Of accompanied,that
R11489 T14711 T14710 arg2Of accompanied,is
R11490 T14713 T14711 arg1Of production,accompanied
R11491 T14713 T14712 arg2Of production,by
R11492 T14713 T14714 arg1Of production,of
R11493 T14715 T14714 arg2Of IL-10,of
R11494 T14719 T14716 arg2Of mechanisms,offers
R11495 T14719 T14717 arg1Of mechanisms,potential
R11496 T14719 T14718 arg1Of mechanisms,additional
R11497 T14719 T14720 arg1Of mechanisms,whereby
R11498 T14723 T14721 arg1Of responses,effector
R11499 T14723 T14722 arg1Of responses,T cell
R115 T207 T203 arg1Of cells,1
R11500 T14723 T14724 arg1Of responses,may
R11501 T14723 T14725 arg1Of responses,be
R11502 T14723 T14726 arg2Of responses,dampened
R11503 T14726 T14720 arg2Of dampened,whereby
R11504 T14726 T14724 arg2Of dampened,may
R11505 T14726 T14725 arg2Of dampened,be
R11506 T14726 T14727 arg1Of dampened,during
R11507 T14729 T14727 arg2Of disease,during
R11508 T14729 T14728 arg1Of disease,chronic
R11509 T14734 T14730 arg2Of model,Using
R11510 T14734 T14731 arg1Of model,an
R11511 T14734 T14732 arg1Of model,in vivo
R11512 T14734 T14733 arg1Of model,transfer
R11513 T14734 T14735 arg1Of model,of
R11514 T14739 T14735 arg2Of cells,of
R11515 T14739 T14736 arg1Of cells,DO11.10
R11516 T14739 T14737 arg1Of cells,TCR
R11517 T14739 T14738 arg1Of cells,transgenic
R11518 T14739 T14740 arg1Of cells,(
R11519 T14741 T14740 arg2Of Castro,(
R11520 T14741 T14742 arg1Of Castro,et al.
R11521 T14741 T14743 arg1Of Castro,","
R11522 T14744 T14743 arg2Of 2000,","
R11523 T14745 T14740 arg3Of ),(
R11524 T14747 T14730 arg1Of we,Using
R11525 T14747 T14748 arg1Of we,showed
R11526 T14748 T14730 modOf showed,Using
R11527 T14748 T14746 arg1Of showed,","
R11528 T14752 T14750 arg1Of cells,IL-10-producing
R11529 T14752 T14751 arg1Of cells,Th1
R11530 T14752 T14753 arg1Of cells,were
R11531 T14752 T14754 arg2Of cells,differentiated
R11532 T14754 T14748 arg2Of differentiated,showed
R11533 T14754 T14749 arg1Of differentiated,that
R11534 T14754 T14753 arg2Of differentiated,were
R11535 T14754 T14755 arg1Of differentiated,in
R11536 T14757 T14755 arg2Of presence,in
R11537 T14757 T14756 arg1Of presence,the
R11538 T14757 T14758 arg1Of presence,of
R11539 T14760 T14758 arg2Of doses,of
R11540 T14760 T14759 arg1Of doses,high
R11541 T14760 T14761 arg1Of doses,of
R11542 T14763 T14764 arg1Of protein,and
R11543 T14764 T14761 arg2Of and,of
R11544 T14764 T14762 arg1Of and,OVA
R11545 T14765 T14764 arg2Of LPS,and
R11546 T14766 T14767 arg1Of We,showed
R11547 T14767 T14768 arg1Of showed,here
R11548 T14771 T14770 arg1Of induction,this
R11549 T14771 T14772 arg1Of induction,of
R11550 T14771 T14776 arg1Of induction,in vivo
R11551 T14771 T14777 arg1Of induction,was
R11552 T14771 T14784 arg2Of induction,reduced
R11553 T14775 T14772 arg2Of cells,of
R11554 T14775 T14773 arg1Of cells,IL-10
R11555 T14775 T14774 arg1Of cells,in Th1
R11556 T14778 T14780 arg1Of markedly,but
R11557 T14780 T14779 arg1Of but,","
R11558 T14780 T14781 arg1Of but,not
R11559 T14782 T14780 arg2Of totally,but
R11560 T14784 T14767 arg2Of reduced,showed
R11561 T14784 T14769 arg1Of reduced,that
R11562 T14784 T14777 arg2Of reduced,was
R11563 T14784 T14778 arg1Of reduced,markedly
R11564 T14784 T14782 arg1Of reduced,totally
R11565 T14784 T14783 arg1Of reduced,","
R11566 T14784 T14785 arg1Of reduced,in
R11567 T14784 T14794 arg1Of reduced,(
R11568 T14787 T14785 arg2Of T cells,in
R11569 T14787 T14786 arg1Of T cells,STAT4-deficient
R11570 T14788 T14784 arg3Of as,reduced
R11571 T14789 T14788 arg2Of observed,as
R11572 T14789 T14790 arg1Of observed,during
R11573 T14793 T14790 arg2Of infection,during
R11574 T14793 T14791 arg1Of infection,T.
R11575 T14793 T14792 arg1Of infection,gondii
R11576 T14796 T14794 arg2Of et al.,(
R11577 T14796 T14795 arg1Of et al.,Jankovic
R11578 T14796 T14797 arg1Of et al.,","
R11579 T14798 T14797 arg2Of 2002,","
R11580 T14799 T14794 arg3Of ),(
R11581 T14803 T14800 arg1Of activation,A
R11582 T14803 T14801 arg1Of activation,high
R11583 T14803 T14802 arg1Of activation,antigenic
R11584 T14803 T14804 arg1Of activation,during
R11585 T14803 T14825 arg1Of activation,may
R11586 T14803 T14826 arg1Of activation,compensate
R11587 T14807 T14805 arg1Of infection,T.
R11588 T14807 T14806 arg1Of infection,gondii
R11589 T14807 T14808 arg1Of infection,or
R11590 T14808 T14804 arg2Of or,during
R11591 T14808 T14812 arg2Of or,delivered
R11592 T14811 T14808 arg2Of doses,or
R11593 T14811 T14809 arg1Of doses,high
R11594 T14811 T14810 arg1Of doses,antigen
R11595 T14812 T14813 arg1Of delivered,in
R11596 T14812 T14818 arg1Of delivered,","
R11597 T14812 T14819 arg1Of delivered,as
R11598 T14815 T14813 arg2Of presence,in
R11599 T14815 T14814 arg1Of presence,the
R116 T207 T204 arg1Of cells,(
R11600 T14815 T14816 arg1Of presence,of
R11601 T14817 T14816 arg2Of LPS,of
R11602 T14820 T14819 arg2Of seen,as
R11603 T14820 T14821 arg1Of seen,in
R11604 T14823 T14821 arg2Of system,in
R11605 T14823 T14822 arg1Of system,our
R11606 T14826 T14824 arg1Of compensate,","
R11607 T14826 T14825 arg2Of compensate,may
R11608 T14826 T14827 arg1Of compensate,for
R11609 T14830 T14827 arg2Of requirement,for
R11610 T14830 T14828 arg1Of requirement,an
R11611 T14830 T14829 arg1Of requirement,absolute
R11612 T14830 T14831 arg1Of requirement,for
R11613 T14832 T14831 arg2Of IL-12,for
R11614 T14832 T14833 arg1Of IL-12,in
R11615 T14835 T14833 arg2Of induction,in
R11616 T14835 T14834 arg1Of induction,the
R11617 T14835 T14836 arg1Of induction,of
R11618 T14835 T14838 arg1Of induction,by
R11619 T14837 T14836 arg2Of IL-10,of
R11620 T14840 T14838 arg2Of cells,by
R11621 T14840 T14839 arg1Of cells,Th1
R11622 T14844 T14841 arg2Of system,In
R11623 T14844 T14842 arg1Of system,our
R11624 T14844 T14843 arg1Of system,in vitro
R11625 T14847 T14846 arg2Of stimulation,repeated
R11626 T14847 T14848 arg1Of stimulation,of
R11627 T14847 T14851 arg1Of stimulation,with
R11628 T14847 T14855 arg1Of stimulation,allowed
R11629 T14850 T14848 arg2Of cells,of
R11630 T14850 T14849 arg1Of cells,Th1
R11631 T14854 T14851 arg2Of doses,with
R11632 T14854 T14852 arg1Of doses,high
R11633 T14854 T14853 arg1Of doses,antigen
R11634 T14855 T14841 arg1Of allowed,In
R11635 T14855 T14845 arg1Of allowed,","
R11636 T14857 T14855 arg2Of development,allowed
R11637 T14857 T14856 arg1Of development,the
R11638 T14857 T14858 arg1Of development,of
R11639 T14860 T14858 arg2Of cells,of
R11640 T14860 T14859 arg1Of cells,Th1
R11641 T14860 T14861 arg1Of cells,producing
R11642 T14861 T14863 arg1Of producing,in
R11643 T14862 T14861 arg2Of IL-10,producing
R11644 T14866 T14863 arg2Of manner,in
R11645 T14866 T14864 arg1Of manner,an
R11646 T14866 T14865 arg1Of manner,IL-12-dependent
R11647 T14868 T14867 arg1Of production,IL-10
R11648 T14868 T14869 arg1Of production,by
R11649 T14868 T14879 arg1Of production,was
R11650 T14868 T14880 arg1Of production,independent
R11651 T14871 T14869 arg2Of cells,by
R11652 T14871 T14870 arg1Of cells,Th1
R11653 T14871 T14872 arg2Of cells,induced
R11654 T14876 T14874 arg1Of dose,high
R11655 T14876 T14875 arg1Of dose,antigen
R11656 T14876 T14877 arg1Of dose,and
R11657 T14877 T14872 arg1Of and,induced
R11658 T14877 T14873 arg2Of and,by
R11659 T14878 T14877 arg2Of IL-12,and
R11660 T14879 T14883 arg1Of was,","
R11661 T14879 T14884 arg1Of was,in
R11662 T14880 T14879 arg2Of independent,was
R11663 T14880 T14881 arg1Of independent,of
R11664 T14882 T14881 arg2Of IFN-γ,of
R11665 T14885 T14884 arg2Of keeping,in
R11666 T14885 T14886 arg1Of keeping,with
R11667 T14888 T14886 arg2Of findings,with
R11668 T14888 T14887 arg1Of findings,previous
R11669 T14888 T14889 arg1Of findings,(
R11670 T14891 T14889 arg2Of et al.,(
R11671 T14891 T14890 arg1Of et al.,Jankovic
R11672 T14891 T14892 arg1Of et al.,","
R11673 T14893 T14892 arg2Of 2002,","
R11674 T14894 T14889 arg3Of ),(
R11675 T14898 T14897 arg1Of role,a
R11676 T14898 T14899 arg1Of role,for
R11677 T14898 T14901 arg1Of role,in
R11678 T14898 T14914 arg1Of role,has
R11679 T14898 T14915 arg1Of role,been
R11680 T14898 T14916 arg2Of role,suggested
R11681 T14900 T14899 arg2Of IFN-γ,for
R11682 T14902 T14901 arg2Of mediating,in
R11683 T14902 T14908 arg1Of mediating,during
R11684 T14904 T14902 arg2Of reactivation,mediating
R11685 T14904 T14903 arg1Of reactivation,IL-10
R11686 T14904 T14905 arg1Of reactivation,by
R11687 T14907 T14905 arg2Of cells,by
R11688 T14907 T14906 arg1Of cells,Th1
R11689 T14910 T14908 arg2Of infection,during
R11690 T14910 T14909 arg1Of infection,secondary
R11691 T14910 T14911 arg1Of infection,with
R11692 T14913 T14911 arg2Of gondii,with
R11693 T14913 T14912 arg1Of gondii,T.
R11694 T14916 T14895 arg1Of suggested,However
R11695 T14916 T14896 arg1Of suggested,","
R11696 T14916 T14914 arg2Of suggested,has
R11697 T14916 T14915 arg2Of suggested,been
R11698 T14916 T14917 arg1Of suggested,(
R11699 T14919 T14917 arg2Of et al.,(
R117 T208 T191 arg1Of are,However
R11700 T14919 T14918 arg1Of et al.,Shaw
R11701 T14919 T14920 arg1Of et al.,","
R11702 T14921 T14920 arg2Of 2006,","
R11703 T14922 T14917 arg3Of ),(
R11704 T14923 T14924 arg1Of We,have
R11705 T14923 T14925 arg1Of We,found
R11706 T14925 T14924 arg2Of found,have
R11707 T14928 T14927 arg1Of T cells,CD4+
R11708 T14928 T14929 arg2Of T cells,exposed
R11709 T14928 T14936 arg1Of T cells,do
R11710 T14928 T14938 arg1Of T cells,express
R11711 T14928 T14944 arg1Of T cells,can
R11712 T14928 T14945 arg1Of T cells,be
R11713 T14928 T14946 arg2Of T cells,induced
R11714 T14928 T14948 arg1Of T cells,produce
R11715 T14929 T14930 arg1Of exposed,to
R11716 T14933 T14930 arg2Of dose,to
R11717 T14933 T14931 arg1Of dose,a
R11718 T14933 T14932 arg1Of dose,high
R11719 T14933 T14934 arg1Of dose,of
R11720 T14935 T14934 arg2Of antigen,of
R11721 T14938 T14936 arg2Of express,do
R11722 T14938 T14937 arg1Of express,not
R11723 T14938 T14940 arg1Of express,upon
R11724 T14938 T14943 arg1Of express,but
R11725 T14939 T14938 arg2Of IL-10,express
R11726 T14941 T14940 arg2Of restimulation,upon
R11727 T14943 T14925 arg2Of but,found
R11728 T14943 T14926 arg1Of but,that
R11729 T14943 T14942 arg1Of but,","
R11730 T14946 T14943 arg2Of induced,but
R11731 T14946 T14944 arg2Of induced,can
R11732 T14946 T14945 arg2Of induced,be
R11733 T14948 T14946 arg3Of produce,induced
R11734 T14948 T14947 arg1Of produce,to
R11735 T14948 T14950 arg1Of produce,upon
R11736 T14948 T14952 arg1Of produce,to
R11737 T14948 T14958 arg1Of produce,in
R11738 T14948 T14962 arg1Of produce,in
R11739 T14949 T14948 arg2Of IL-10,produce
R11740 T14951 T14950 arg2Of re-exposure,upon
R11741 T14955 T14952 arg2Of dose,to
R11742 T14955 T14953 arg1Of dose,a
R11743 T14955 T14954 arg1Of dose,high
R11744 T14955 T14956 arg1Of dose,of
R11745 T14957 T14956 arg2Of antigen,of
R11746 T14961 T14958 arg2Of phase,in
R11747 T14961 T14959 arg1Of phase,the
R11748 T14961 T14960 arg1Of phase,recall
R11749 T14962 T14963 arg1Of in,the
R11750 T14962 T14965 arg1Of in,of
R11751 T14964 T14962 arg2Of absence,in
R11752 T14967 T14962 arg3Of IL-12,in
R11753 T14967 T14966 arg2Of IL-12,added
R11754 T14970 T14971 arg1Of this,is
R11755 T14970 T14972 arg1Of this,dependent
R11756 T14971 T14968 arg1Of is,However
R11757 T14971 T14969 arg1Of is,","
R11758 T14972 T14971 arg2Of dependent,is
R11759 T14972 T14973 arg1Of dependent,on
R11760 T14975 T14973 arg2Of induction,on
R11761 T14975 T14974 arg1Of induction,the
R11762 T14975 T14976 arg1Of induction,of
R11763 T14975 T14978 arg1Of induction,by
R11764 T14977 T14976 arg2Of IL-12,of
R11765 T14980 T14978 arg2Of DCs,by
R11766 T14980 T14979 arg1Of DCs,antigen-presenting
R11767 T14982 T14981 arg1Of combination,The
R11768 T14982 T14983 arg1Of combination,of
R11769 T14982 T14990 arg1Of combination,resulted
R11770 T14982 T14999 arg1Of combination,correlated
R11771 T14987 T14985 arg1Of dose,high
R11772 T14987 T14986 arg1Of dose,antigen
R11773 T14987 T14988 arg1Of dose,and
R11774 T14988 T14983 arg2Of and,of
R11775 T14988 T14984 arg1Of and,both
R11776 T14989 T14988 arg2Of IL-12,and
R11777 T14990 T14991 arg1Of resulted,in
R11778 T14990 T14998 arg1Of resulted,and
R11779 T14994 T14991 arg2Of levels,in
R11780 T14994 T14992 arg1Of levels,the
R11781 T14994 T14993 arg1Of levels,highest
R11782 T14994 T14995 arg1Of levels,of
R11783 T14997 T14995 arg2Of production,of
R11784 T14997 T14996 arg1Of production,IL-10
R11785 T14999 T14998 arg2Of correlated,and
R11786 T14999 T15000 arg1Of correlated,with
R11787 T15003 T15000 arg2Of levels,with
R11788 T15003 T15001 arg1Of levels,the
R11789 T15003 T15002 arg1Of levels,high
R11790 T15003 T15004 arg1Of levels,of
R11791 T15005 T15006 arg1Of ERK1,and
R11792 T15007 T15006 arg2Of ERK2,and
R11793 T15008 T15004 arg2Of activation,of
R11794 T15008 T15005 arg1Of activation,ERK1
R11795 T15008 T15007 arg1Of activation,ERK2
R11796 T15011 T15009 arg1Of expression,The
R11797 T15011 T15010 arg2Of expression,increased
R11798 T15011 T15012 arg1Of expression,of
R11799 T15011 T15019 arg1Of expression,will
R118 T208 T192 arg1Of are,","
R11800 T15011 T15020 arg1Of expression,induce
R11801 T15011 T15027 arg1Of expression,suggests
R11802 T15013 T15012 arg2Of IFN-γ,of
R11803 T15013 T15014 arg2Of IFN-γ,observed
R11804 T15014 T15015 arg1Of observed,during
R11805 T15018 T15015 arg2Of phase,during
R11806 T15018 T15016 arg1Of phase,the
R11807 T15018 T15017 arg1Of phase,secondary
R11808 T15020 T15019 arg2Of induce,will
R11809 T15020 T15026 arg1Of induce,and
R11810 T15023 T15020 arg2Of production,induce
R11811 T15023 T15021 arg2Of production,increased
R11812 T15023 T15022 arg1Of production,IL-12
R11813 T15023 T15024 arg1Of production,by
R11814 T15025 T15024 arg2Of DCs,by
R11815 T15027 T15026 arg2Of suggests,and
R11816 T15032 T15029 arg2Of activation,repeated
R11817 T15032 T15030 arg1Of activation,high-level
R11818 T15032 T15031 arg1Of activation,TCR
R11819 T15032 T15033 arg1Of activation,feeds
R11820 T15032 T15036 arg1Of activation,upregulate
R11821 T15033 T15027 arg2Of feeds,suggests
R11822 T15033 T15028 arg1Of feeds,that
R11823 T15033 T15034 arg1Of feeds,back
R11824 T15033 T15035 modOf feeds,to
R11825 T15036 T15035 arg1Of upregulate,to
R11826 T15038 T15036 arg2Of production,upregulate
R11827 T15038 T15037 arg1Of production,IL-12
R11828 T15038 T15039 arg1Of production,by
R11829 T15040 T15039 arg2Of DC,by
R11830 T15044 T15042 arg2Of likely,is
R11831 T15044 T15043 arg1Of likely,thus
R11832 T15049 T15046 arg2Of infection,in
R11833 T15049 T15047 arg1Of infection,T.
R11834 T15049 T15048 arg1Of infection,gondii
R11835 T15049 T15050 arg1Of infection,in vivo
R11836 T15049 T15051 arg1Of infection,(
R11837 T15053 T15051 arg2Of et al.,(
R11838 T15053 T15052 arg1Of et al.,Shaw
R11839 T15053 T15054 arg1Of et al.,","
R11840 T15055 T15054 arg2Of 2006,","
R11841 T15056 T15051 arg3Of ),(
R11842 T15059 T15058 arg1Of requirement,the
R11843 T15059 T15060 arg1Of requirement,for
R11844 T15059 T15066 arg1Of requirement,was
R11845 T15059 T15067 arg1Of requirement,for
R11846 T15061 T15060 arg2Of IFN-γ,for
R11847 T15061 T15063 arg1Of IFN-γ,induce
R11848 T15063 T15060 arg3Of induce,for
R11849 T15063 T15062 arg1Of induce,to
R11850 T15064 T15063 arg2Of IL-10,induce
R11851 T15066 T15041 arg1Of was,It
R11852 T15066 T15042 arg1Of was,is
R11853 T15066 T15044 arg1Of was,likely
R11854 T15066 T15045 arg1Of was,that
R11855 T15066 T15046 arg1Of was,in
R11856 T15066 T15057 arg1Of was,","
R11857 T15066 T15065 arg1Of was,","
R11858 T15067 T15066 arg2Of for,was
R11859 T15069 T15067 arg2Of upregulation,for
R11860 T15069 T15068 arg1Of upregulation,feedback
R11861 T15069 T15070 arg1Of upregulation,of
R11862 T15071 T15070 arg2Of IL-12,of
R11863 T15071 T15072 arg1Of IL-12,by
R11864 T15073 T15072 arg2Of DCs,by
R11865 T15073 T15074 arg1Of DCs,","
R11866 T15073 T15075 arg1Of DCs,which
R11867 T15073 T15078 arg1Of DCs,induced
R11868 T15077 T15076 arg2Of turn,in
R11869 T15078 T15076 arg1Of induced,in
R11870 T15078 T15080 arg1Of induced,in
R11871 T15079 T15078 arg2Of IL-10,induced
R11872 T15083 T15080 arg2Of cells,in
R11873 T15083 T15081 arg1Of cells,the
R11874 T15083 T15082 arg1Of cells,Th1
R11875 T15085 T15086 arg1Of IL-10,may
R11876 T15085 T15087 arg1Of IL-10,be
R11877 T15085 T15089 arg2Of IL-10,regulated
R11878 T15089 T15084 arg2Of regulated,Although
R11879 T15089 T15086 arg2Of regulated,may
R11880 T15089 T15087 arg2Of regulated,be
R11881 T15089 T15088 arg1Of regulated,differentially
R11882 T15089 T15090 arg1Of regulated,in
R11883 T15089 T15095 arg1Of regulated,as
R11884 T15089 T15099 arg1Of regulated,(
R11885 T15091 T15092 arg1Of Th1,and
R11886 T15093 T15092 arg2Of Th2,and
R11887 T15094 T15090 arg2Of cells,in
R11888 T15094 T15091 arg1Of cells,Th1
R11889 T15094 T15093 arg1Of cells,Th2
R11890 T15098 T15095 arg2Of reported,as
R11891 T15098 T15096 arg2Of reported,has
R11892 T15098 T15097 arg2Of reported,been
R11893 T15101 T15100 arg1Of et al.,Chang
R11894 T15101 T15102 arg1Of et al.,","
R11895 T15101 T15104 arg1Of et al.,;
R11896 T15103 T15102 arg2Of 2007,","
R11897 T15104 T15099 arg2Of ;,(
R11898 T15105 T15104 arg2Of Wang,;
R11899 T15105 T15106 arg1Of Wang,et al.
R119 T209 T208 arg2Of undefined,are
R11900 T15105 T15107 arg1Of Wang,","
R11901 T15108 T15107 arg2Of 2005,","
R11902 T15109 T15099 arg3Of ),(
R11903 T15112 T15111 arg1Of studies,some
R11904 T15112 T15113 arg1Of studies,suggest
R11905 T15113 T15120 arg1Of suggest,but
R11906 T15115 T15113 arg2Of existence,suggest
R11907 T15115 T15114 arg1Of existence,the
R11908 T15115 T15116 arg1Of existence,of
R11909 T15118 T15116 arg2Of pathways,of
R11910 T15118 T15117 arg1Of pathways,common
R11911 T15120 T15084 arg1Of but,Although
R11912 T15120 T15110 arg1Of but,","
R11913 T15120 T15119 arg1Of but,","
R11914 T15123 T15121 arg1Of basis,the
R11915 T15123 T15122 arg1Of basis,molecular
R11916 T15123 T15124 arg1Of basis,for
R11917 T15123 T15126 arg1Of basis,is
R11918 T15123 T15129 arg1Of basis,unclear
R11919 T15125 T15124 arg2Of these,for
R11920 T15126 T15120 arg2Of is,but
R11921 T15126 T15128 arg1Of is,yet
R11922 T15128 T15127 arg1Of yet,as
R11923 T15129 T15126 arg2Of unclear,is
R11924 T15132 T15130 arg1Of signals,Costimulatory
R11925 T15132 T15131 arg1Of signals,OX-40
R11926 T15132 T15133 arg1Of signals,have
R11927 T15132 T15134 arg1Of signals,been
R11928 T15132 T15135 arg2Of signals,shown
R11929 T15132 T15138 arg1Of signals,regulate
R11930 T15135 T15133 arg2Of shown,have
R11931 T15135 T15134 arg2Of shown,been
R11932 T15138 T15135 arg3Of regulate,shown
R11933 T15138 T15136 arg1Of regulate,to
R11934 T15138 T15137 arg1Of regulate,negatively
R11935 T15138 T15148 arg1Of regulate,in
R11936 T15138 T15153 arg1Of regulate,","
R11937 T15138 T15154 arg1Of regulate,whereas
R11938 T15140 T15138 arg2Of production,regulate
R11939 T15140 T15139 arg1Of production,IL-10
R11940 T15140 T15141 arg1Of production,(
R11941 T15143 T15141 arg2Of et al.,(
R11942 T15143 T15142 arg1Of et al.,Ito
R11943 T15143 T15144 arg1Of et al.,","
R11944 T15145 T15144 arg2Of 2005,","
R11945 T15146 T15141 arg3Of ),(
R11946 T15148 T15147 arg1Of in,both
R11947 T15149 T15150 arg1Of Th1,and
R11948 T15151 T15150 arg2Of Th2,and
R11949 T15152 T15148 arg2Of cells,in
R11950 T15152 T15149 arg1Of cells,Th1
R11951 T15152 T15151 arg1Of cells,Th2
R11952 T15156 T15155 arg1Of signaling,ICOS
R11953 T15156 T15157 arg1Of signaling,has
R11954 T15156 T15158 arg1Of signaling,been
R11955 T15156 T15159 arg2Of signaling,suggested
R11956 T15156 T15161 arg1Of signaling,induce
R11957 T15159 T15154 arg2Of suggested,whereas
R11958 T15159 T15157 arg2Of suggested,has
R11959 T15159 T15158 arg2Of suggested,been
R11960 T15161 T15159 arg3Of induce,suggested
R11961 T15161 T15160 arg1Of induce,to
R11962 T15161 T15174 arg1Of induce,in
R11963 T15162 T15161 arg2Of IL-10,induce
R11964 T15162 T15163 arg1Of IL-10,(
R11965 T15165 T15164 arg1Of et al.,Ito
R11966 T15165 T15166 arg1Of et al.,","
R11967 T15165 T15168 arg1Of et al.,;
R11968 T15167 T15166 arg2Of 2007,","
R11969 T15168 T15163 arg2Of ;,(
R11970 T15170 T15168 arg2Of et al.,;
R11971 T15170 T15169 arg1Of et al.,Witsch
R11972 T15170 T15171 arg1Of et al.,","
R11973 T15172 T15171 arg2Of 2002,","
R11974 T15173 T15163 arg3Of ),(
R11975 T15176 T15177 arg1Of Th1,and
R11976 T15177 T15175 arg1Of and,both
R11977 T15178 T15177 arg2Of Th2,and
R11978 T15179 T15174 arg2Of cells,in
R11979 T15179 T15176 arg1Of cells,Th1
R11980 T15179 T15178 arg1Of cells,Th2
R11981 T15184 T15182 arg2Of cases,in
R11982 T15184 T15183 arg1Of cases,some
R11983 T15187 T15186 arg1Of signaling,ICOS
R11984 T15187 T15189 arg1Of signaling,regulates
R11985 T15189 T15180 arg1Of regulates,However
R11986 T15189 T15181 arg1Of regulates,","
R11987 T15189 T15182 arg1Of regulates,in
R11988 T15189 T15185 arg1Of regulates,","
R11989 T15189 T15188 arg1Of regulates,also
R11990 T15191 T15192 arg1Of production,and
R11991 T15193 T15192 arg2Of Th2,and
R11992 T15194 T15189 arg2Of responses,regulates
R11993 T15194 T15190 arg1Of responses,IL-4
R11994 T15194 T15191 arg1Of responses,production
R11995 T15194 T15193 arg1Of responses,Th2
R11996 T15194 T15195 arg1Of responses,(
R11997 T15197 T15195 arg2Of et al.,(
R11998 T15197 T15196 arg1Of et al.,Greenwald
R11999 T15197 T15198 arg1Of et al.,","
R120 T210 T211 arg1Of We,showed
R12000 T15199 T15198 arg2Of 2005,","
R12001 T15200 T15195 arg3Of ),(
R12002 T15201 T15203 arg1Of We,provide
R12003 T15203 T15202 arg1Of provide,now
R12004 T15203 T15226 arg1Of provide,","
R12005 T15203 T15227 arg1Of provide,although
R12006 T15206 T15203 arg2Of mechanism,provide
R12007 T15206 T15204 arg1Of mechanism,a
R12008 T15206 T15205 arg1Of mechanism,common
R12009 T15206 T15207 arg1Of mechanism,of
R12010 T15206 T15212 arg1Of mechanism,for
R12011 T15208 T15209 arg1Of ERK1,and
R12012 T15210 T15209 arg2Of ERK2,and
R12013 T15211 T15207 arg2Of activation,of
R12014 T15211 T15208 arg1Of activation,ERK1
R12015 T15211 T15210 arg1Of activation,ERK2
R12016 T15214 T15212 arg2Of regulation,for
R12017 T15214 T15213 arg1Of regulation,the
R12018 T15214 T15215 arg1Of regulation,of
R12019 T15217 T15215 arg2Of production,of
R12020 T15217 T15216 arg1Of production,IL-10
R12021 T15217 T15218 arg1Of production,in
R12022 T15219 T15220 arg1Of Th1,","
R12023 T15220 T15223 arg1Of ",",and
R12024 T15221 T15220 arg2Of Th2,","
R12025 T15223 T15222 arg1Of and,","
R12026 T15224 T15223 arg2Of Th17,and
R12027 T15225 T15218 arg2Of cells,in
R12028 T15225 T15219 arg1Of cells,Th1
R12029 T15225 T15221 arg1Of cells,Th2
R12030 T15225 T15224 arg1Of cells,Th17
R12031 T15229 T15228 arg1Of subset,each
R12032 T15229 T15230 arg1Of subset,differentiates
R12033 T15230 T15227 arg2Of differentiates,although
R12034 T15230 T15231 arg1Of differentiates,along
R12035 T15233 T15234 arg1Of distinct,and
R12036 T15235 T15234 arg2Of subset-specific,and
R12037 T15237 T15231 arg2Of pathway,along
R12038 T15237 T15232 arg1Of pathway,a
R12039 T15237 T15233 arg1Of pathway,distinct
R12040 T15237 T15235 arg1Of pathway,subset-specific
R12041 T15237 T15236 arg1Of pathway,transcriptional
R12042 T15238 T15239 arg1Of This,reinforces
R12043 T15241 T15239 arg2Of fact,reinforces
R12044 T15241 T15240 arg1Of fact,the
R12045 T15243 T15244 arg1Of IL-10,is
R12046 T15243 T15253 arg1Of IL-10,is
R12047 T15243 T15254 arg2Of IL-10,produced
R12048 T15244 T15245 arg1Of is,not
R12049 T15244 T15251 arg1Of is,but
R12050 T15249 T15244 arg2Of cytokine,is
R12051 T15249 T15246 arg1Of cytokine,a
R12052 T15249 T15247 arg1Of cytokine,Th
R12053 T15249 T15248 arg1Of cytokine,cell-subset-specific
R12054 T15251 T15241 arg2Of but,fact
R12055 T15251 T15242 arg1Of but,that
R12056 T15251 T15250 arg1Of but,","
R12057 T15254 T15251 arg2Of produced,but
R12058 T15254 T15252 arg1Of produced,instead
R12059 T15254 T15253 arg2Of produced,is
R12060 T15254 T15255 arg1Of produced,in
R12061 T15254 T15260 arg1Of produced,during
R12062 T15258 T15257 arg1Of regulated,tightly
R12063 T15259 T15255 arg2Of fashion,in
R12064 T15259 T15256 arg1Of fashion,a
R12065 T15259 T15258 arg1Of fashion,regulated
R12066 T15263 T15260 arg2Of pathway,during
R12067 T15263 T15261 arg1Of pathway,each
R12068 T15263 T15262 arg1Of pathway,differentiation
R12069 T15265 T15264 arg2Of note,Of
R12070 T15268 T15267 arg1Of role,a
R12071 T15268 T15269 arg1Of role,for
R12072 T15268 T15274 arg1Of role,in
R12073 T15268 T15280 arg1Of role,has
R12074 T15268 T15282 arg1Of role,been
R12075 T15268 T15283 arg2Of role,described
R12076 T15270 T15271 arg1Of ERK1,and
R12077 T15272 T15271 arg2Of ERK2,and
R12078 T15273 T15269 arg2Of activation,for
R12079 T15273 T15270 arg1Of activation,ERK1
R12080 T15273 T15272 arg1Of activation,ERK2
R12081 T15276 T15274 arg2Of induction,in
R12082 T15276 T15275 arg1Of induction,the
R12083 T15276 T15277 arg1Of induction,of
R12084 T15279 T15277 arg2Of production,of
R12085 T15279 T15278 arg1Of production,IL-10
R12086 T15283 T15264 arg1Of described,Of
R12087 T15283 T15266 arg1Of described,","
R12088 T15283 T15280 arg2Of described,has
R12089 T15283 T15281 arg1Of described,already
R12090 T15283 T15282 arg2Of described,been
R12091 T15283 T15284 arg1Of described,for
R12092 T15285 T15286 arg1Of macrophages,and
R12093 T15286 T15284 arg2Of and,for
R12094 T15286 T15288 arg1Of and,(
R12095 T15287 T15286 arg2Of DC,and
R12096 T15290 T15289 arg1Of et al.,Agrawal
R12097 T15290 T15291 arg1Of et al.,","
R12098 T15290 T15293 arg1Of et al.,;
R12099 T15292 T15291 arg2Of 2006,","
R121 T213 T214 arg1Of development,of
R12100 T15293 T15288 arg2Of ;,(
R12101 T15294 T15293 arg2Of Hacker,;
R12102 T15294 T15295 arg1Of Hacker,et al.
R12103 T15294 T15296 arg1Of Hacker,","
R12104 T15297 T15296 arg2Of 1999,","
R12105 T15298 T15288 arg3Of ),(
R12106 T15301 T15299 arg1Of regulation,Differential
R12107 T15301 T15300 arg1Of regulation,transcriptional
R12108 T15301 T15302 arg1Of regulation,of
R12109 T15301 T15304 arg1Of regulation,in
R12110 T15301 T15309 arg1Of regulation,has
R12111 T15301 T15310 arg1Of regulation,been
R12112 T15301 T15311 arg2Of regulation,suggested
R12113 T15303 T15302 arg2Of IL-10,of
R12114 T15305 T15306 arg1Of Th1,and
R12115 T15307 T15306 arg2Of Th2,and
R12116 T15308 T15304 arg2Of cells,in
R12117 T15308 T15305 arg1Of cells,Th1
R12118 T15308 T15307 arg1Of cells,Th2
R12119 T15311 T15309 arg2Of suggested,has
R12120 T15311 T15310 arg2Of suggested,been
R12121 T15311 T15312 arg1Of suggested,(
R12122 T15311 T15324 arg1Of suggested,and
R12123 T15314 T15313 arg1Of et al.,Chang
R12124 T15314 T15315 arg1Of et al.,","
R12125 T15314 T15317 arg1Of et al.,;
R12126 T15316 T15315 arg2Of 2007,","
R12127 T15317 T15312 arg2Of ;,(
R12128 T15318 T15317 arg2Of Wang,;
R12129 T15318 T15319 arg1Of Wang,et al.
R12130 T15318 T15320 arg1Of Wang,","
R12131 T15321 T15320 arg2Of 2005,","
R12132 T15322 T15312 arg3Of ),(
R12133 T15324 T15323 arg1Of and,","
R12134 T15327 T15325 arg1Of acetylation,extensive
R12135 T15327 T15326 arg1Of acetylation,histone
R12136 T15327 T15328 arg1Of acetylation,of
R12137 T15327 T15332 arg1Of acetylation,is
R12138 T15327 T15333 arg1Of acetylation,detectable
R12139 T15331 T15328 arg2Of gene,of
R12140 T15331 T15329 arg1Of gene,the
R12141 T15331 T15330 arg1Of gene,IL-10
R12142 T15332 T15324 arg2Of is,and
R12143 T15333 T15332 arg2Of detectable,is
R12144 T15333 T15334 arg1Of detectable,in
R12145 T15336 T15335 arg1Of polarized,fully
R12146 T15338 T15336 arg1Of cells,polarized
R12147 T15338 T15337 arg1Of cells,Th2
R12148 T15338 T15340 arg1Of cells,but
R12149 T15340 T15334 arg2Of but,in
R12150 T15340 T15339 arg1Of but,","
R12151 T15340 T15341 arg1Of but,not
R12152 T15343 T15340 arg2Of cells,but
R12153 T15343 T15342 arg1Of cells,Th1
R12154 T15343 T15344 arg1Of cells,(
R12155 T15346 T15344 arg2Of et al.,(
R12156 T15346 T15345 arg1Of et al.,Chang
R12157 T15346 T15347 arg1Of et al.,","
R12158 T15348 T15347 arg2Of 2007,","
R12159 T15349 T15344 arg3Of ),(
R12160 T15350 T15351 arg1Of We,provide
R12161 T15352 T15351 arg2Of evidence,provide
R12162 T15354 T15355 arg1Of IL-10,is
R12163 T15354 T15356 arg2Of IL-10,produced
R12164 T15356 T15353 arg1Of produced,that
R12165 T15356 T15355 arg2Of produced,is
R12166 T15356 T15357 arg1Of produced,in
R12167 T15356 T15361 arg1Of produced,and
R12168 T15360 T15357 arg2Of cells,in
R12169 T15360 T15358 arg1Of cells,canonical
R12170 T15360 T15359 arg1Of cells,Th1
R12171 T15361 T15352 arg2Of and,evidence
R12172 T15362 T15361 arg2Of that,and
R12173 T15364 T15363 arg1Of expression,its
R12174 T15364 T15365 arg1Of expression,correlates
R12175 T15365 T15362 arg2Of correlates,that
R12176 T15365 T15366 arg1Of correlates,with
R12177 T15365 T15376 arg1Of correlates,","
R12178 T15365 T15377 arg1Of correlates,in
R12179 T15368 T15367 arg1Of expression,the
R12180 T15368 T15369 arg1Of expression,of
R12181 T15368 T15371 arg1Of expression,and
R12182 T15370 T15369 arg2Of T-bet,of
R12183 T15371 T15366 arg2Of and,with
R12184 T15375 T15371 arg2Of production,and
R12185 T15375 T15372 arg1Of production,the
R12186 T15375 T15373 arg1Of production,highest
R12187 T15375 T15374 arg1Of production,IFN-γ
R12188 T15378 T15377 arg2Of keeping,in
R12189 T15378 T15379 arg1Of keeping,with
R12190 T15381 T15379 arg2Of observations,with
R12191 T15381 T15380 arg1Of observations,our
R12192 T15385 T15383 arg1Of stimulation,high-dose
R12193 T15385 T15384 arg1Of stimulation,antigen
R12194 T15385 T15386 arg1Of stimulation,and
R12195 T15386 T15389 arg1Of and,are
R12196 T15386 T15390 arg2Of and,required
R12197 T15388 T15386 arg2Of signaling,and
R12198 T15388 T15387 arg1Of signaling,IL-12
R12199 T15390 T15381 arg2Of required,observations
R122 T213 T218 arg1Of development,required
R12200 T15390 T15382 arg1Of required,that
R12201 T15390 T15389 arg2Of required,are
R12202 T15390 T15391 arg1Of required,for
R12203 T15392 T15393 arg1Of IL-10,and
R12204 T15394 T15393 arg2Of IFN-γ,and
R12205 T15395 T15391 arg2Of expression,for
R12206 T15395 T15392 arg1Of expression,IL-10
R12207 T15395 T15394 arg1Of expression,IFN-γ
R12208 T15396 T15397 arg1Of It,has
R12209 T15396 T15399 arg1Of It,been
R12210 T15396 T15400 arg2Of It,shown
R12211 T15400 T15397 arg2Of shown,has
R12212 T15400 T15398 arg1Of shown,also
R12213 T15400 T15399 arg2Of shown,been
R12214 T15402 T15403 arg1Of maintenance,of
R12215 T15402 T15406 arg1Of maintenance,is
R12216 T15402 T15407 arg1Of maintenance,conditional
R12217 T15405 T15403 arg2Of expression,of
R12218 T15405 T15404 arg1Of expression,IL-10
R12219 T15406 T15400 arg3Of is,shown
R12220 T15406 T15401 arg1Of is,that
R12221 T15406 T15412 arg1Of is,unless
R12222 T15407 T15406 arg2Of conditional,is
R12223 T15407 T15408 arg1Of conditional,on
R12224 T15409 T15410 arg1Of IL-12,or
R12225 T15410 T15408 arg2Of or,on
R12226 T15411 T15410 arg2Of IL-4,or
R12227 T15415 T15413 arg1Of gene,the
R12228 T15415 T15414 arg1Of gene,IL-10
R12229 T15415 T15416 arg1Of gene,is
R12230 T15415 T15417 arg2Of gene,imprinted
R12231 T15417 T15412 arg2Of imprinted,unless
R12232 T15417 T15416 arg2Of imprinted,is
R12233 T15419 T15417 arg1Of GATA-3,imprinted
R12234 T15419 T15418 arg2Of GATA-3,by
R12235 T15419 T15420 arg1Of GATA-3,(
R12236 T15419 T15426 arg1Of GATA-3,","
R12237 T15419 T15427 arg1Of GATA-3,which
R12238 T15419 T15428 arg1Of GATA-3,can
R12239 T15419 T15429 arg1Of GATA-3,remodel
R12240 T15422 T15420 arg2Of et al.,(
R12241 T15422 T15421 arg1Of et al.,Chang
R12242 T15422 T15423 arg1Of et al.,","
R12243 T15424 T15423 arg2Of 2007,","
R12244 T15425 T15420 arg3Of ),(
R12245 T15429 T15428 arg2Of remodel,can
R12246 T15429 T15433 arg1Of remodel,","
R12247 T15429 T15435 modOf remodel,explaining
R12248 T15432 T15429 arg2Of locus,remodel
R12249 T15432 T15430 arg1Of locus,the
R12250 T15432 T15431 arg1Of locus,IL-10
R12251 T15435 T15434 arg1Of explaining,thus
R12252 T15438 T15435 arg2Of amounts,explaining
R12253 T15438 T15436 arg1Of amounts,the
R12254 T15438 T15437 arg1Of amounts,highest
R12255 T15438 T15439 arg1Of amounts,of
R12256 T15438 T15441 arg2Of amounts,produced
R12257 T15440 T15439 arg2Of IL-10,of
R12258 T15444 T15441 arg1Of cells,produced
R12259 T15444 T15442 arg2Of cells,by
R12260 T15444 T15443 arg1Of cells,Th2
R12261 T15444 T15445 arg1Of cells,(
R12262 T15447 T15446 arg1Of et al.,Chang
R12263 T15447 T15448 arg1Of et al.,","
R12264 T15447 T15450 arg1Of et al.,;
R12265 T15449 T15448 arg2Of 2007,","
R12266 T15450 T15445 arg2Of ;,(
R12267 T15451 T15450 arg2Of Shoemaker,;
R12268 T15451 T15452 arg1Of Shoemaker,et al.
R12269 T15451 T15453 arg1Of Shoemaker,","
R12270 T15454 T15453 arg2Of 2006,","
R12271 T15455 T15445 arg3Of ),(
R12272 T15456 T15457 arg1Of We,show
R12273 T15457 T15458 arg1Of show,here
R12274 T15462 T15463 arg1Of dose,and
R12275 T15463 T15460 arg1Of and,high
R12276 T15463 T15461 arg1Of and,antigen
R12277 T15463 T15466 arg1Of and,downregulate
R12278 T15464 T15463 arg2Of IL-12,and
R12279 T15466 T15457 arg2Of downregulate,show
R12280 T15466 T15459 arg1Of downregulate,that
R12281 T15466 T15465 arg1Of downregulate,drastically
R12282 T15466 T15469 arg1Of downregulate,","
R12283 T15466 T15470 modOf downregulate,suggesting
R12284 T15468 T15466 arg2Of expression,downregulate
R12285 T15468 T15467 arg1Of expression,Gata-3
R12286 T15473 T15472 arg1Of factors,additional
R12287 T15473 T15474 arg1Of factors,are
R12288 T15473 T15475 arg1Of factors,in
R12289 T15474 T15470 arg2Of are,suggesting
R12290 T15474 T15471 arg1Of are,that
R12291 T15474 T15484 arg1Of are,","
R12292 T15474 T15486 arg1Of are,transiently
R12293 T15475 T15474 arg2Of in,are
R12294 T15476 T15475 arg2Of place,in
R12295 T15476 T15477 modOf place,to
R12296 T15478 T15477 arg1Of induce,to
R12297 T15480 T15478 arg2Of expression,induce
R12298 T15480 T15479 arg1Of expression,IL-10
R12299 T15480 T15481 arg1Of expression,in
R123 T217 T214 arg2Of cells,of
R12300 T15483 T15481 arg2Of cells,in
R12301 T15483 T15482 arg1Of cells,Th1
R12302 T15486 T15485 arg1Of transiently,albeit
R12303 T15487 T15488 arg1Of Expression,of
R12304 T15487 T15490 arg1Of Expression,was
R12305 T15487 T15492 arg2Of Expression,diminished
R12306 T15487 T15501 arg1Of Expression,was
R12307 T15487 T15503 arg2Of Expression,maintained
R12308 T15487 T15507 arg1Of Expression,present
R12309 T15489 T15488 arg2Of c-maf,of
R12310 T15492 T15490 arg2Of diminished,was
R12311 T15492 T15491 arg1Of diminished,greatly
R12312 T15492 T15499 arg1Of diminished,and
R12313 T15496 T15492 arg1Of doses,diminished
R12314 T15496 T15493 arg2Of doses,by
R12315 T15496 T15494 arg1Of doses,high
R12316 T15496 T15495 arg1Of doses,antigen
R12317 T15496 T15497 arg1Of doses,in
R12318 T15498 T15497 arg2Of T cells,in
R12319 T15503 T15506 arg1Of maintained,and
R12320 T15505 T15503 arg1Of IL-12,maintained
R12321 T15505 T15504 arg2Of IL-12,by
R12322 T15506 T15499 arg2Of and,and
R12323 T15506 T15500 arg1Of and,yet
R12324 T15506 T15501 arg2Of and,was
R12325 T15506 T15502 arg1Of and,unexpectedly
R12326 T15507 T15506 arg2Of present,and
R12327 T15507 T15508 arg1Of present,in
R12328 T15510 T15508 arg2Of cells,in
R12329 T15510 T15509 arg1Of cells,Th17
R12330 T15513 T15512 arg1Of expression,c-maf
R12331 T15513 T15514 arg1Of expression,is
R12332 T15513 T15515 arg1Of expression,common
R12333 T15513 T15530 arg1Of expression,is
R12334 T15513 T15531 arg1Of expression,dependent
R12335 T15514 T15525 arg1Of is,and
R12336 T15514 T15526 arg1Of is,","
R12337 T15515 T15514 arg2Of common,is
R12338 T15515 T15516 arg1Of common,to
R12339 T15518 T15519 arg1Of Th1,","
R12340 T15519 T15522 arg1Of ",",and
R12341 T15520 T15519 arg2Of Th2,","
R12342 T15522 T15521 arg1Of and,","
R12343 T15523 T15522 arg2Of Th17,and
R12344 T15524 T15516 arg2Of cells,to
R12345 T15524 T15517 arg1Of cells,IL-10-producing
R12346 T15524 T15518 arg1Of cells,Th1
R12347 T15524 T15520 arg1Of cells,Th2
R12348 T15524 T15523 arg1Of cells,Th17
R12349 T15526 T15511 arg1Of ",",That
R12350 T15526 T15543 arg1Of ",",is
R12351 T15526 T15544 arg1Of ",",of
R12352 T15528 T15527 arg2Of IL-10,like
R12353 T15530 T15526 arg2Of is,","
R12354 T15530 T15527 arg1Of is,like
R12355 T15530 T15529 arg1Of is,","
R12356 T15531 T15530 arg2Of dependent,is
R12357 T15531 T15532 arg1Of dependent,on
R12358 T15534 T15532 arg2Of activation,on
R12359 T15534 T15533 arg1Of activation,ERK
R12360 T15534 T15535 arg1Of activation,in
R12361 T15534 T15540 arg1Of activation,for
R12362 T15536 T15537 arg1Of Th1,and
R12363 T15538 T15537 arg2Of Th17,and
R12364 T15539 T15535 arg2Of cells,in
R12365 T15539 T15536 arg1Of cells,Th1
R12366 T15539 T15538 arg1Of cells,Th17
R12367 T15542 T15540 arg2Of expression,for
R12368 T15542 T15541 arg1Of expression,its
R12369 T15543 T15546 arg1Of is,because
R12370 T15544 T15543 arg2Of of,is
R12371 T15545 T15544 arg2Of interest,of
R12372 T15547 T15548 arg1Of c-Maf,has
R12373 T15547 T15549 arg1Of c-Maf,been
R12374 T15547 T15550 arg2Of c-Maf,shown
R12375 T15547 T15552 arg1Of c-Maf,be
R12376 T15550 T15546 arg2Of shown,because
R12377 T15550 T15548 arg2Of shown,has
R12378 T15550 T15549 arg2Of shown,been
R12379 T15552 T15550 arg3Of be,shown
R12380 T15552 T15551 arg1Of be,to
R12381 T15556 T15552 arg2Of factor,be
R12382 T15556 T15553 arg1Of factor,an
R12383 T15556 T15554 arg1Of factor,essential
R12384 T15556 T15555 arg1Of factor,transcription
R12385 T15556 T15557 arg1Of factor,for
R12386 T15559 T15557 arg2Of expression,for
R12387 T15559 T15558 arg1Of expression,IL-10
R12388 T15559 T15560 arg1Of expression,in
R12389 T15561 T15560 arg2Of macrophages,in
R12390 T15561 T15562 arg1Of macrophages,(
R12391 T15564 T15562 arg2Of et al.,(
R12392 T15564 T15563 arg1Of et al.,Cao
R12393 T15564 T15565 arg1Of et al.,","
R12394 T15566 T15565 arg2Of 2005,","
R12395 T15567 T15562 arg3Of ),(
R12396 T15569 T15568 arg2Of summary,In
R12397 T15571 T15572 arg1Of we,show
R12398 T15572 T15568 arg1Of show,In
R12399 T15572 T15570 arg1Of show,","
R124 T217 T215 arg1Of cells,IL-10-producing
R12400 T15575 T15576 arg1Of Th1,","
R12401 T15576 T15579 arg1Of ",",and
R12402 T15577 T15576 arg2Of Th2,","
R12403 T15579 T15578 arg1Of and,","
R12404 T15580 T15579 arg2Of Th17,and
R12405 T15583 T15575 arg1Of subsets,Th1
R12406 T15583 T15577 arg1Of subsets,Th2
R12407 T15583 T15580 arg1Of subsets,Th17
R12408 T15583 T15581 arg1Of subsets,CD4+
R12409 T15583 T15582 arg1Of subsets,T cell
R12410 T15583 T15584 arg1Of subsets,differentiate
R12411 T15584 T15574 arg2Of differentiate,although
R12412 T15584 T15585 arg1Of differentiate,along
R12413 T15587 T15586 arg1Of signaling,distinct
R12414 T15587 T15588 arg1Of signaling,and
R12415 T15588 T15585 arg2Of and,along
R12416 T15590 T15588 arg2Of pathways,and
R12417 T15590 T15589 arg1Of pathways,transcriptional
R12418 T15592 T15593 arg1Of they,can
R12419 T15592 T15595 arg1Of they,be
R12420 T15592 T15596 arg2Of they,induced
R12421 T15596 T15572 arg2Of induced,show
R12422 T15596 T15573 arg1Of induced,that
R12423 T15596 T15574 arg1Of induced,although
R12424 T15596 T15591 arg1Of induced,","
R12425 T15596 T15593 arg2Of induced,can
R12426 T15596 T15594 arg1Of induced,all
R12427 T15596 T15595 arg2Of induced,be
R12428 T15596 T15597 modOf induced,to
R12429 T15598 T15597 arg1Of make,to
R12430 T15599 T15598 arg2Of IL-10,make
R12431 T15600 T15601 arg1Of ERK1,and
R12432 T15601 T15604 arg1Of and,is
R12433 T15601 T15605 arg2Of and,required
R12434 T15603 T15601 arg2Of activation,and
R12435 T15603 T15602 arg1Of activation,ERK2
R12436 T15605 T15604 arg2Of required,is
R12437 T15605 T15606 arg1Of required,for
R12438 T15605 T15609 arg1Of required,by
R12439 T15608 T15606 arg2Of production,for
R12440 T15608 T15607 arg1Of production,IL-10
R12441 T15614 T15609 arg2Of subsets,by
R12442 T15614 T15610 arg1Of subsets,all
R12443 T15614 T15611 arg1Of subsets,these
R12444 T15614 T15612 arg1Of subsets,Th
R12445 T15614 T15613 arg1Of subsets,cell
R12446 T15615 T15617 arg1Of With,to
R12447 T15616 T15615 arg2Of regard,With
R12448 T15619 T15615 arg3Of expression,With
R12449 T15619 T15618 arg1Of expression,the
R12450 T15619 T15620 arg1Of expression,of
R12451 T15619 T15622 arg1Of expression,by
R12452 T15621 T15620 arg2Of IL-10,of
R12453 T15624 T15622 arg2Of cells,by
R12454 T15624 T15623 arg1Of cells,Th1
R12455 T15627 T15626 arg1Of data,our
R12456 T15627 T15628 arg1Of data,provide
R12457 T15628 T15615 arg1Of provide,With
R12458 T15628 T15625 arg1Of provide,","
R12459 T15630 T15628 arg2Of mechanism,provide
R12460 T15630 T15629 arg1Of mechanism,a
R12461 T15630 T15631 arg1Of mechanism,for
R12462 T15632 T15631 arg2Of how,for
R12463 T15634 T15633 arg1Of expression,IL-10
R12464 T15634 T15635 arg1Of expression,is
R12465 T15634 T15636 arg2Of expression,induced
R12466 T15634 T15639 arg2Of expression,amplified
R12467 T15634 T15641 arg2Of expression,regulated
R12468 T15636 T15637 arg1Of induced,and
R12469 T15637 T15632 arg1Of and,how
R12470 T15637 T15635 arg2Of and,is
R12471 T15639 T15640 arg1Of amplified,and
R12472 T15640 T15637 arg2Of and,and
R12473 T15640 T15638 arg1Of and,then
R12474 T15641 T15640 arg2Of regulated,and
R12475 T15644 T15639 arg1Of levels,amplified
R12476 T15644 T15641 arg1Of levels,regulated
R12477 T15644 T15642 arg2Of levels,by
R12478 T15644 T15643 arg1Of levels,the
R12479 T15644 T15645 arg1Of levels,of
R12480 T15646 T15647 arg1Of antigen,and
R12481 T15647 T15645 arg2Of and,of
R12482 T15647 T15649 arg2Of and,encountered
R12483 T15648 T15647 arg2Of IL-12,and
R12484 T15649 T15650 arg1Of encountered,in
R12485 T15652 T15650 arg2Of environment,in
R12486 T15652 T15651 arg1Of environment,the
R12487 T15653 T15654 arg1Of This,provides
R12488 T15656 T15654 arg2Of mechanism,provides
R12489 T15656 T15655 arg1Of mechanism,a
R12490 T15656 T15657 arg1Of mechanism,whereby
R12491 T15660 T15658 arg1Of cell,a
R12492 T15660 T15659 arg1Of cell,Th1
R12493 T15660 T15661 arg1Of cell,responds
R12494 T15660 T15699 arg1Of cell,prevent
R12495 T15661 T15662 arg1Of responds,to
R12496 T15661 T15665 arg1Of responds,","
R12497 T15661 T15666 modOf responds,reflecting
R12498 T15661 T15672 arg1Of responds,","
R12499 T15661 T15673 modOf responds,to
R125 T217 T216 arg1Of cells,Th1
R12500 T15661 T15682 modOf responds,to
R12501 T15661 T15697 arg1Of responds,and
R12502 T15664 T15662 arg2Of signals,to
R12503 T15664 T15663 arg1Of signals,extrinsic
R12504 T15668 T15666 arg2Of inflammation,reflecting
R12505 T15668 T15667 arg2Of inflammation,increased
R12506 T15668 T15669 arg1Of inflammation,in
R12507 T15671 T15669 arg2Of tissue,in
R12508 T15671 T15670 arg1Of tissue,the
R12509 T15675 T15673 arg1Of regulate,to
R12510 T15675 T15674 arg1Of regulate,tightly
R12511 T15675 T15680 arg1Of regulate,so
R12512 T15675 T15681 arg1Of regulate,as
R12513 T15677 T15675 arg2Of production,regulate
R12514 T15677 T15676 arg1Of production,the
R12515 T15677 T15678 arg1Of production,of
R12516 T15679 T15678 arg2Of IL-10,of
R12517 T15683 T15681 arg2Of allow,as
R12518 T15683 T15682 arg1Of allow,to
R12519 T15686 T15683 arg2Of response,allow
R12520 T15686 T15684 arg1Of response,a
R12521 T15686 T15685 arg1Of response,protective
R12522 T15686 T15688 arg1Of response,eradicate
R12523 T15688 T15683 arg3Of eradicate,allow
R12524 T15688 T15687 arg1Of eradicate,to
R12525 T15690 T15688 arg2Of pathogen,eradicate
R12526 T15690 T15689 arg1Of pathogen,a
R12527 T15690 T15691 arg1Of pathogen,with
R12528 T15693 T15691 arg2Of damage,with
R12529 T15693 T15692 arg1Of damage,minimal
R12530 T15693 T15694 arg1Of damage,to
R12531 T15696 T15694 arg2Of host,to
R12532 T15696 T15695 arg1Of host,the
R12533 T15697 T15657 arg2Of and,whereby
R12534 T15699 T15697 arg2Of prevent,and
R12535 T15699 T15698 arg1Of prevent,also
R12536 T15701 T15699 arg2Of infection,prevent
R12537 T15701 T15700 arg1Of infection,chronic
R12538 T15705 T15704 arg1Of findings,our
R12539 T15705 T15706 arg1Of findings,have
R12540 T15705 T15723 arg1Of findings,may
R12541 T15705 T15724 arg1Of findings,be
R12542 T15705 T15725 arg1Of findings,of
R12543 T15706 T15715 arg1Of have,during
R12544 T15706 T15722 arg1Of have,and
R12545 T15708 T15706 arg2Of implications,have
R12546 T15708 T15707 arg1Of implications,important
R12547 T15708 T15709 arg1Of implications,for
R12548 T15711 T15709 arg2Of regulation,for
R12549 T15711 T15710 arg1Of regulation,the
R12550 T15711 T15712 arg1Of regulation,of
R12551 T15714 T15712 arg2Of production,of
R12552 T15714 T15713 arg1Of production,IL-10
R12553 T15719 T15715 arg2Of response,during
R12554 T15719 T15716 arg1Of response,an
R12555 T15719 T15717 arg1Of response,inflammatory
R12556 T15719 T15718 arg1Of response,Th1
R12557 T15719 T15720 arg1Of response,in
R12558 T15721 T15720 arg2Of infection,in
R12559 T15722 T15702 arg1Of and,Moreover
R12560 T15722 T15703 arg1Of and,","
R12561 T15724 T15722 arg2Of be,and
R12562 T15724 T15723 arg2Of be,may
R12563 T15725 T15724 arg2Of of,be
R12564 T15726 T15725 arg2Of relevance,of
R12565 T15726 T15727 arg1Of relevance,for
R12566 T15726 T15733 arg1Of relevance,for
R12567 T15727 T15732 arg1Of for,and
R12568 T15729 T15727 arg2Of design,for
R12569 T15729 T15728 arg1Of design,the
R12570 T15729 T15730 arg1Of design,of
R12571 T15731 T15730 arg2Of vaccines,of
R12572 T15733 T15732 arg2Of for,and
R12573 T15734 T15733 arg2Of strategies,for
R12574 T15734 T15735 arg1Of strategies,in
R12575 T15736 T15735 arg2Of immunotherapy,in
R12576 T15736 T15737 arg1Of immunotherapy,in
R12577 T15739 T15737 arg2Of diseases,in
R12578 T15739 T15738 arg1Of diseases,infectious
R126 T218 T211 arg2Of required,showed
R127 T218 T212 arg1Of required,that
R128 T221 T219 arg1Of receptor,high
R129 T221 T220 arg1Of receptor,T cell
R130 T221 T222 arg1Of receptor,(
R131 T223 T222 arg2Of TCR,(
R132 T224 T222 arg3Of ),(
R133 T225 T221 arg1Of ligation,receptor
R134 T225 T226 arg1Of ligation,","
R135 T226 T229 arg1Of ",",and
R136 T228 T226 arg2Of ERK1,","
R137 T228 T227 arg1Of ERK1,sustained
R138 T229 T235 arg1Of and,and
R139 T233 T229 arg2Of phosphorylation,and
R140 T233 T230 arg1Of phosphorylation,ERK2
R141 T233 T231 arg1Of phosphorylation,MAP
R142 T233 T232 arg1Of phosphorylation,kinases
R143 T235 T218 arg2Of and,required
R144 T235 T234 arg1Of and,","
R145 T240 T235 arg2Of activation,and
R146 T240 T236 arg1Of activation,IL-12-induced
R147 T240 T237 arg1Of activation,STAT4
R148 T240 T238 arg1Of activation,transcription
R149 T240 T239 arg1Of activation,factor
R150 T243 T241 arg2Of triggering,Repeated
R151 T243 T242 arg1Of triggering,TCR
R15108 T19140 T19141 arg1Of Isolation,of
R15109 T19140 T19146 arg1Of Isolation,of
R15110 T19140 T19152 arg1Of Isolation,for
R15111 T19141 T19145 arg1Of of,and
R15112 T19144 T19141 arg2Of Cells,of
R15113 T19144 T19142 arg1Of Cells,CD4+
R15114 T19144 T19143 arg1Of Cells,T
R15115 T19146 T19145 arg2Of of,and
R15116 T19148 T19147 arg1Of DC,Splenic
R15117 T19148 T19149 arg1Of DC,and
R15118 T19149 T19146 arg2Of and,of
R15119 T19151 T19149 arg2Of Culture,and
R15120 T19151 T19150 arg1Of Culture,Cell
R15121 T19156 T19152 arg2Of Differentiation,for
R15122 T19156 T19153 arg1Of Differentiation,T
R15123 T19156 T19154 arg1Of Differentiation,Cell
R15124 T19156 T19155 arg1Of Differentiation,Phenotype
R15125 T19158 T19157 arg1Of cells,T
R15126 T19158 T19159 arg1Of cells,were
R15127 T19158 T19160 arg2Of cells,sorted
R15128 T19160 T19159 arg2Of sorted,were
R15129 T19160 T19161 arg1Of sorted,for
R15130 T19160 T19172 arg1Of sorted,on
R15131 T19162 T19163 arg1Of CD4+CD62Lhi,","
R15132 T19163 T19166 arg1Of ",",or
R15133 T19164 T19163 arg2Of CD4+CD62LhiCD25−,","
R15134 T19166 T19161 arg2Of or,for
R15135 T19166 T19165 arg1Of or,","
R15136 T19166 T19168 arg1Of or,to
R15137 T19167 T19166 arg2Of CD4+CD44loCD25−,or
R15138 T19170 T19169 arg1Of 98,>
R15139 T19171 T19168 arg2Of %,to
R15140 T19171 T19170 arg1Of %,98
R15141 T19175 T19172 arg2Of cytometer,on
R15142 T19175 T19173 arg1Of cytometer,a
R15143 T19175 T19174 arg1Of cytometer,Moflo
R15144 T19175 T19176 arg1Of cytometer,(
R15145 T19175 T19179 arg1Of cytometer,as
R15146 T19177 T19176 arg2Of Cytomation,(
R15147 T19178 T19176 arg3Of ),(
R15148 T19179 T19180 arg1Of as,before
R15149 T19179 T19181 arg1Of as,(
R15150 T19183 T19182 arg1Of et al.,Shoemaker
R15151 T19183 T19184 arg1Of et al.,","
R15152 T19183 T19186 arg1Of et al.,;
R15153 T19185 T19184 arg2Of 2006,","
R15154 T19186 T19181 arg2Of ;,(
R15155 T19187 T19186 arg2Of Veldhoen,;
R15156 T19187 T19188 arg1Of Veldhoen,et al.
R15157 T19187 T19189 arg1Of Veldhoen,","
R15158 T19190 T19189 arg2Of 2009,","
R15159 T19191 T19181 arg3Of ),(
R15160 T19194 T19192 arg2Of cases,In
R15161 T19194 T19193 arg1Of cases,most
R15162 T19196 T19197 arg1Of experiments,were
R15163 T19196 T19198 arg2Of experiments,reproduced
R15164 T19198 T19192 arg1Of reproduced,In
R15165 T19198 T19195 arg1Of reproduced,","
R15166 T19198 T19197 arg2Of reproduced,were
R15167 T19198 T19199 arg1Of reproduced,with
R15168 T19201 T19199 arg2Of type,with
R15169 T19201 T19200 arg1Of type,each
R15170 T19201 T19202 arg1Of type,of
R15171 T19201 T19207 arg1Of type,with
R15172 T19206 T19202 arg2Of population,of
R15173 T19206 T19203 arg2Of population,purified
R15174 T19206 T19204 arg1Of population,CD4+
R15175 T19206 T19205 arg1Of population,T cell
R15176 T19209 T19207 arg2Of results,with
R15177 T19209 T19208 arg1Of results,similar
R15178 T19209 T19210 arg2Of results,obtained
R15179 T19212 T19211 arg1Of DCs,Splenic
R15180 T19212 T19213 arg1Of DCs,were
R15181 T19212 T19214 arg2Of DCs,prepared
R15182 T19214 T19213 arg2Of prepared,were
R15183 T19214 T19215 arg1Of prepared,as
R15184 T19214 T19217 arg1Of prepared,(
R15185 T19214 T19224 arg1Of prepared,and
R15186 T19216 T19215 arg2Of described,as
R15187 T19219 T19217 arg2Of et al.,(
R15188 T19219 T19218 arg1Of et al.,Hosken
R15189 T19219 T19220 arg1Of et al.,","
R15190 T19221 T19220 arg2Of 1995,","
R15191 T19222 T19217 arg3Of ),(
R15192 T19224 T19223 arg1Of and,","
R15193 T19228 T19225 arg1Of cells,sort
R15194 T19228 T19226 arg2Of cells,purified
R15195 T19228 T19227 arg1Of cells,CD11c+
R15196 T19228 T19229 arg1Of cells,were
R15197 T19228 T19230 arg2Of cells,added
R15198 T19230 T19224 arg2Of added,and
R15199 T19230 T19229 arg2Of added,were
R152 T243 T244 arg1Of triggering,led
R15200 T19230 T19231 arg1Of added,to
R15201 T19234 T19231 arg2Of culture,to
R15202 T19234 T19232 arg1Of culture,the
R15203 T19234 T19233 arg1Of culture,T cell
R15204 T19238 T19235 arg2Of T cells,Purified
R15205 T19238 T19236 arg1Of T cells,DO11.10
R15206 T19238 T19237 arg1Of T cells,CD4+
R15207 T19238 T19239 arg1Of T cells,(
R15208 T19238 T19245 arg1Of T cells,were
R15209 T19238 T19246 arg2Of T cells,cultured
R15210 T19240 T19239 arg2Of 1,(
R15211 T19240 T19241 arg1Of 1,×
R15212 T19243 T19241 arg2Of cells/ml,×
R15213 T19243 T19242 arg1Of cells/ml,105
R15214 T19244 T19239 arg3Of ),(
R15215 T19246 T19245 arg2Of cultured,were
R15216 T19246 T19247 arg1Of cultured,as
R15217 T19246 T19255 arg1Of cultured,","
R15218 T19246 T19256 arg1Of cultured,in
R15219 T19246 T19269 arg1Of cultured,","
R15220 T19246 T19270 arg1Of cultured,with
R15221 T19247 T19248 arg1Of as,before
R15222 T19247 T19249 arg1Of as,(
R15223 T19251 T19249 arg2Of et al.,(
R15224 T19251 T19250 arg1Of et al.,Hosken
R15225 T19251 T19252 arg1Of et al.,","
R15226 T19253 T19252 arg2Of 1995,","
R15227 T19254 T19249 arg3Of ),(
R15228 T19259 T19256 arg2Of volume,in
R15229 T19259 T19257 arg1Of volume,a
R15230 T19259 T19258 arg1Of volume,total
R15231 T19259 T19260 arg1Of volume,of
R15232 T19259 T19265 arg1Of volume,in
R15233 T19264 T19260 arg2Of medium,of
R15234 T19264 T19261 arg1Of medium,1
R15235 T19264 T19262 arg1Of medium,ml
R15236 T19264 T19263 arg1Of medium,cRPMI
R15237 T19268 T19265 arg2Of plate,in
R15238 T19268 T19266 arg1Of plate,a
R15239 T19268 T19267 arg1Of plate,48-well
R15240 T19272 T19271 arg1Of DCs,splenic
R15241 T19272 T19273 arg1Of DCs,(
R15242 T19272 T19280 arg1Of DCs,and
R15243 T19274 T19275 arg1Of 2,×
R15244 T19276 T19275 arg2Of 104,×
R15245 T19277 T19273 arg2Of cells/ml,(
R15246 T19277 T19274 arg1Of cells/ml,2
R15247 T19277 T19276 arg1Of cells/ml,104
R15248 T19278 T19273 arg3Of ),(
R15249 T19280 T19270 arg2Of and,with
R15250 T19280 T19279 arg1Of and,","
R15251 T19282 T19280 arg2Of amounts,and
R15252 T19282 T19281 arg1Of amounts,varying
R15253 T19282 T19283 arg1Of amounts,of
R15254 T19282 T19286 arg1Of amounts,of
R15255 T19283 T19285 arg1Of of,and
R15256 T19284 T19283 arg2Of OVA,of
R15257 T19286 T19285 arg2Of of,and
R15258 T19287 T19286 arg2Of IL-12,of
R15259 T19289 T19288 arg1Of differentiation,APC-independent
R15260 T19289 T19290 arg1Of differentiation,of
R15261 T19289 T19294 arg1Of differentiation,into
R15262 T19289 T19299 arg1Of differentiation,used
R15263 T19293 T19290 arg2Of T cells,of
R15264 T19293 T19291 arg1Of T cells,naive
R15265 T19293 T19292 arg1Of T cells,CD4+
R15266 T19295 T19296 arg1Of Th1,and
R15267 T19297 T19296 arg2Of Th2,and
R15268 T19298 T19294 arg2Of cells,into
R15269 T19298 T19295 arg1Of cells,Th1
R15270 T19298 T19297 arg1Of cells,Th2
R15271 T19299 T19310 arg1Of used,and
R15272 T19300 T19299 arg2Of stimulation,used
R15273 T19300 T19301 arg1Of stimulation,with
R15274 T19302 T19303 arg1Of anti-CD3,and
R15275 T19303 T19301 arg2Of and,with
R15276 T19304 T19305 arg1Of anti-CD28,and
R15277 T19306 T19305 arg2Of appropriate,and
R15278 T19308 T19303 arg2Of conditions,and
R15279 T19308 T19304 arg1Of conditions,anti-CD28
R15280 T19308 T19306 arg1Of conditions,appropriate
R15281 T19308 T19307 arg1Of conditions,cytokine
R15282 T19310 T19309 arg1Of and,","
R15283 T19312 T19313 arg1Of Th1,and
R15284 T19314 T19313 arg2Of Th2,and
R15285 T19315 T19311 arg1Of cells,control
R15286 T19315 T19312 arg1Of cells,Th1
R15287 T19315 T19314 arg1Of cells,Th2
R15288 T19315 T19316 arg1Of cells,were
R15289 T19315 T19317 arg2Of cells,cultured
R15290 T19317 T19310 arg2Of cultured,and
R15291 T19317 T19316 arg2Of cultured,were
R15292 T19317 T19318 arg1Of cultured,as
R15293 T19319 T19318 arg2Of described,as
R15294 T19319 T19320 arg1Of described,before
R15295 T19323 T19322 arg1Of et al.,Hosken
R15296 T19323 T19324 arg1Of et al.,","
R15297 T19323 T19326 arg1Of et al.,;
R15298 T19325 T19324 arg2Of 1995,","
R15299 T19326 T19320 arg2Of ;,before
R153 T244 T245 arg1Of led,to
R15300 T19326 T19321 arg2Of ;,(
R15301 T19327 T19326 arg2Of Shoemaker,;
R15302 T19327 T19328 arg1Of Shoemaker,et al.
R15303 T19327 T19329 arg1Of Shoemaker,","
R15304 T19330 T19329 arg2Of 2006,","
R15305 T19331 T19321 arg3Of ),(
R15306 T19333 T19332 arg1Of conditions,Culture
R15307 T19333 T19334 arg1Of conditions,for
R15308 T19333 T19337 arg1Of conditions,were
R15309 T19336 T19334 arg2Of cells,for
R15310 T19336 T19335 arg1Of cells,Th17
R15311 T19337 T19338 arg1Of were,as
R15312 T19339 T19338 arg2Of described,as
R15313 T19339 T19340 arg1Of described,before
R15314 T19343 T19340 arg2Of et al.,before
R15315 T19343 T19341 arg2Of et al.,(
R15316 T19343 T19342 arg1Of et al.,Veldhoen
R15317 T19343 T19344 arg1Of et al.,","
R15318 T19345 T19344 arg2Of 2006,","
R15319 T19346 T19341 arg3Of ),(
R15320 T19349 T19350 arg1Of Th1,and
R15321 T19351 T19350 arg2Of Th2,and
R15322 T19352 T19349 arg1Of cells,Th1
R15323 T19352 T19351 arg1Of cells,Th2
R15324 T19352 T19353 arg1Of cells,could
R15325 T19352 T19354 arg1Of cells,be
R15326 T19352 T19355 arg2Of cells,differentiated
R15327 T19355 T19353 arg2Of differentiated,could
R15328 T19355 T19354 arg2Of differentiated,be
R15329 T19355 T19356 arg1Of differentiated,in
R15330 T19355 T19360 arg1Of differentiated,(
R15331 T19355 T19377 arg1Of differentiated,but
R15332 T19357 T19358 arg1Of cRPMI,or
R15333 T19358 T19356 arg2Of or,in
R15334 T19359 T19358 arg2Of IMDM,or
R15335 T19362 T19361 arg1Of et al.,Hosken
R15336 T19362 T19363 arg1Of et al.,","
R15337 T19362 T19365 arg1Of et al.,;
R15338 T19364 T19363 arg2Of 1995,","
R15339 T19365 T19370 arg1Of ;,;
R15340 T19366 T19365 arg2Of Shoemaker,;
R15341 T19366 T19367 arg1Of Shoemaker,et al.
R15342 T19366 T19368 arg1Of Shoemaker,","
R15343 T19369 T19368 arg2Of 2006,","
R15344 T19370 T19360 arg2Of ;,(
R15345 T19371 T19370 arg2Of Veldhoen,;
R15346 T19371 T19372 arg1Of Veldhoen,et al.
R15347 T19371 T19373 arg1Of Veldhoen,","
R15348 T19374 T19373 arg2Of 2006,","
R15349 T19375 T19360 arg3Of ),(
R15350 T19377 T19347 arg1Of but,Importantly
R15351 T19377 T19348 arg1Of but,","
R15352 T19377 T19376 arg1Of but,","
R15353 T19379 T19378 arg1Of cells,Th17
R15354 T19379 T19380 arg1Of cells,were
R15355 T19379 T19382 arg2Of cells,differentiated
R15356 T19382 T19377 arg2Of differentiated,but
R15357 T19382 T19380 arg2Of differentiated,were
R15358 T19382 T19381 arg1Of differentiated,only
R15359 T19382 T19383 arg1Of differentiated,optimally
R15360 T19382 T19384 arg1Of differentiated,in
R15361 T19385 T19384 arg2Of IMDM,in
R15362 T19385 T19386 arg1Of IMDM,(
R15363 T19388 T19386 arg2Of et al.,(
R15364 T19388 T19387 arg1Of et al.,Veldhoen
R15365 T19388 T19389 arg1Of et al.,","
R15366 T19390 T19389 arg2Of 2009,","
R15367 T19391 T19386 arg3Of ),(
R15368 T19395 T19396 arg1Of U0126,or
R15369 T19396 T19393 arg2Of or,indicated
R15370 T19396 T19394 arg1Of or,","
R15371 T19396 T19398 arg1Of or,(
R15372 T19396 T19402 arg1Of or,","
R15373 T19397 T19396 arg2Of PD184352,or
R15374 T19400 T19398 arg2Of inhibitors,(
R15375 T19400 T19399 arg1Of inhibitors,MEK
R15376 T19401 T19398 arg3Of ),(
R15377 T19402 T19408 arg1Of ",",","
R15378 T19403 T19402 arg2Of SB203580,","
R15379 T19403 T19404 arg1Of SB203580,(
R15380 T19406 T19404 arg2Of inhibitor,(
R15381 T19406 T19405 arg1Of inhibitor,p38
R15382 T19407 T19404 arg3Of ),(
R15383 T19408 T19415 arg1Of ",",or
R15384 T19409 T19408 arg2Of CT99021,","
R15385 T19409 T19410 arg1Of CT99021,(
R15386 T19412 T19410 arg2Of inhibitor,(
R15387 T19412 T19411 arg1Of inhibitor,GSK3β
R15388 T19413 T19410 arg3Of ),(
R15389 T19415 T19414 arg1Of or,","
R15390 T19415 T19421 arg1Of or,were
R15391 T19415 T19422 arg1Of or,present
R15392 T19418 T19415 arg2Of amount,or
R15393 T19418 T19416 arg1Of amount,a
R15394 T19418 T19417 arg1Of amount,similar
R15395 T19418 T19419 arg1Of amount,of
R15396 T19420 T19419 arg2Of DMSO,of
R15397 T19421 T19392 arg1Of were,When
R15398 T19422 T19421 arg2Of present,were
R15399 T19422 T19423 arg1Of present,in
R154 T244 T253 arg1Of led,and
R15400 T19425 T19423 arg2Of culture,in
R15401 T19425 T19424 arg1Of culture,the
R15402 T19427 T19426 arg1Of details,More
R15403 T19427 T19428 arg1Of details,of
R15404 T19427 T19432 arg1Of details,are
R15405 T19427 T19433 arg2Of details,provided
R15406 T19431 T19428 arg2Of conditions,of
R15407 T19431 T19429 arg1Of conditions,specific
R15408 T19431 T19430 arg1Of conditions,culture
R15409 T19433 T19432 arg2Of provided,are
R15410 T19433 T19434 arg1Of provided,in
R15411 T19436 T19437 arg1Of S6,and
R15412 T19437 T19434 arg2Of and,in
R15413 T19437 T19435 arg1Of and,Figures
R15414 T19438 T19437 arg2Of S7,and
R155 T248 T245 arg2Of production,to
R156 T248 T246 arg2Of production,enhanced
R157 T248 T247 arg1Of production,IL-10
R15770 T19944 T19943 arg1Of Detection,Cytokine
R15771 T19944 T19945 arg1Of Detection,by
R15772 T19946 T19947 arg1Of ICS,and
R15773 T19947 T19945 arg2Of and,by
R15774 T19948 T19947 arg2Of ELISA,and
R15775 T19951 T19952 arg1Of 5,or
R15776 T19952 T19949 arg2Of or,At
R15777 T19952 T19950 arg1Of or,day
R15778 T19953 T19952 arg2Of 7,or
R15779 T19955 T19956 arg1Of cells,were
R15780 T19955 T19957 arg2Of cells,restimulated
R15781 T19957 T19949 arg1Of restimulated,At
R15782 T19957 T19954 arg1Of restimulated,","
R15783 T19957 T19956 arg2Of restimulated,were
R15784 T19957 T19958 arg1Of restimulated,with
R15785 T19957 T19987 arg1Of restimulated,with
R15786 T19958 T19986 arg1Of with,or
R15787 T19960 T19959 arg2Of anti-CD3,immobilized
R15788 T19960 T19961 arg1Of anti-CD3,(
R15789 T19960 T19965 arg1Of anti-CD3,and
R15790 T19963 T19961 arg2Of μg/ml,(
R15791 T19963 T19962 arg1Of μg/ml,2
R15792 T19964 T19961 arg3Of ),(
R15793 T19965 T19958 arg2Of and,with
R15794 T19965 T19971 arg1Of and,(
R15795 T19966 T19965 arg2Of anti-CD28,and
R15796 T19966 T19967 arg1Of anti-CD28,(
R15797 T19969 T19967 arg2Of μg/ml,(
R15798 T19969 T19968 arg1Of μg/ml,2
R15799 T19970 T19967 arg3Of ),(
R158 T248 T249 arg1Of production,by
R15800 T19973 T19971 arg2Of hr,(
R15801 T19973 T19972 arg1Of hr,4
R15802 T19973 T19974 arg1Of hr,with
R15803 T19973 T19980 arg1Of hr,in
R15804 T19975 T19974 arg2Of BrefeldinA,with
R15805 T19975 T19976 arg1Of BrefeldinA,[
R15806 T19978 T19976 arg2Of μg/ml,[
R15807 T19978 T19977 arg1Of μg/ml,10
R15808 T19979 T19976 arg3Of ],[
R15809 T19984 T19980 arg2Of hr,in
R15810 T19984 T19981 arg1Of hr,the
R15811 T19984 T19982 arg1Of hr,last
R15812 T19984 T19983 arg1Of hr,2
R15813 T19985 T19971 arg3Of ),(
R15814 T19987 T19986 arg2Of with,or
R15815 T19988 T19989 arg1Of PdBU,and
R15816 T19989 T19987 arg2Of and,with
R15817 T19990 T19989 arg2Of Ionomycin,and
R15818 T19990 T19991 arg1Of Ionomycin,(
R15819 T19993 T19991 arg2Of hr,(
R15820 T19993 T19992 arg1Of hr,5
R15821 T19993 T19994 arg1Of hr,with
R15822 T19995 T19994 arg2Of BrefeldinA,with
R15823 T19995 T19996 arg1Of BrefeldinA,[
R15824 T19998 T19996 arg2Of μg/ml,[
R15825 T19998 T19997 arg1Of μg/ml,1
R15826 T19999 T19996 arg3Of ],[
R15827 T20000 T19991 arg3Of ),(
R15828 T20003 T20001 arg2Of FACS,After
R15829 T20003 T20002 arg1Of FACS,ICS
R15830 T20005 T20006 arg1Of data,were
R15831 T20005 T20007 arg2Of data,collected
R15832 T20005 T20016 arg2Of data,analyzed
R15833 T20007 T20008 arg1Of collected,on
R15834 T20007 T20015 arg1Of collected,and
R15835 T20010 T20008 arg2Of FACSCalibur,on
R15836 T20010 T20009 arg1Of FACSCalibur,a
R15837 T20010 T20011 arg1Of FACSCalibur,(
R15838 T20013 T20011 arg2Of Dickinson,(
R15839 T20013 T20012 arg1Of Dickinson,Becton
R15840 T20014 T20011 arg3Of ),(
R15841 T20015 T20001 arg1Of and,After
R15842 T20015 T20004 arg1Of and,","
R15843 T20015 T20006 arg2Of and,were
R15844 T20016 T20015 arg2Of analyzed,and
R15845 T20016 T20017 arg1Of analyzed,with
R15846 T20018 T20017 arg2Of FlowJo,with
R15847 T20018 T20019 arg1Of FlowJo,(
R15848 T20021 T20019 arg2Of Star,(
R15849 T20021 T20020 arg1Of Star,Tree
R15850 T20022 T20019 arg3Of ),(
R15851 T20024 T20023 arg2Of ELISA,For
R15852 T20026 T20027 arg1Of cells,were
R15853 T20026 T20029 arg2Of cells,restimulated
R15854 T20029 T20027 arg2Of restimulated,were
R15855 T20029 T20028 arg1Of restimulated,similarly
R15856 T20029 T20030 arg1Of restimulated,for
R15857 T20029 T20033 arg1Of restimulated,and
R15858 T20032 T20030 arg2Of hr,for
R15859 T20032 T20031 arg1Of hr,48
R15860 T20033 T20023 arg1Of and,For
R15861 T20033 T20025 arg1Of and,","
R15862 T20034 T20035 arg1Of supernatant,was
R15863 T20034 T20036 arg2Of supernatant,collected
R15864 T20034 T20038 arg2Of supernatant,analyzed
R15865 T20036 T20037 arg1Of collected,and
R15866 T20037 T20033 arg2Of and,and
R15867 T20037 T20035 arg2Of and,was
R15868 T20037 T20039 arg1Of and,for
R15869 T20038 T20037 arg2Of analyzed,and
R15870 T20040 T20041 arg1Of IL-4,","
R15871 T20041 T20044 arg1Of ",",and
R15872 T20042 T20041 arg2Of IL-10,","
R15873 T20044 T20039 arg2Of and,for
R15874 T20044 T20043 arg1Of and,","
R15875 T20044 T20046 arg1Of and,as
R15876 T20045 T20044 arg2Of IFN-γ,and
R15877 T20047 T20046 arg2Of described,as
R15878 T20047 T20048 arg1Of described,before
R15879 T20051 T20048 arg2Of et al.,before
R15880 T20051 T20049 arg2Of et al.,(
R15881 T20051 T20050 arg1Of et al.,Shoemaker
R15882 T20051 T20052 arg1Of et al.,","
R15883 T20053 T20052 arg2Of 2006,","
R15884 T20054 T20049 arg3Of ),(
R159 T251 T249 arg2Of cells,by
R160 T251 T250 arg1Of cells,Th1
R16013 T20253 T20251 arg2Of Studies,In
R16014 T20253 T20252 arg1Of Studies,Vivo
R16015 T20255 T20254 arg1Of mice,BALB/c
R16016 T20255 T20256 arg1Of mice,were
R16017 T20255 T20257 arg2Of mice,injected
R16018 T20257 T20256 arg2Of injected,were
R16019 T20257 T20258 arg1Of injected,intravenously
R16020 T20257 T20259 arg1Of injected,(
R16021 T20257 T20262 arg1Of injected,with
R16022 T20260 T20259 arg2Of i.v.,(
R16023 T20261 T20259 arg3Of ),(
R16024 T20269 T20262 arg2Of suspension,with
R16025 T20269 T20263 arg1Of suspension,a
R16026 T20269 T20264 arg1Of suspension,red
R16027 T20269 T20265 arg1Of suspension,blood
R16028 T20269 T20266 arg1Of suspension,cell-depleted
R16029 T20269 T20267 arg1Of suspension,single-cell
R16030 T20269 T20268 arg1Of suspension,spleen
R16031 T20269 T20270 arg1Of suspension,(
R16032 T20269 T20276 arg1Of suspension,(
R16033 T20269 T20282 arg1Of suspension,from
R16034 T20271 T20272 arg1Of 2.5,×
R16035 T20273 T20272 arg2Of 107,×
R16036 T20274 T20270 arg2Of cells,(
R16037 T20274 T20271 arg1Of cells,2.5
R16038 T20274 T20273 arg1Of cells,107
R16039 T20275 T20270 arg3Of ),(
R16040 T20278 T20276 arg2Of et al.,(
R16041 T20278 T20277 arg1Of et al.,Castro
R16042 T20278 T20279 arg1Of et al.,","
R16043 T20280 T20279 arg2Of 2000,","
R16044 T20281 T20276 arg3Of ),(
R16045 T20284 T20283 arg1Of WT,DO11.10
R16046 T20284 T20285 arg1Of WT,or
R16047 T20285 T20282 arg2Of or,from
R16048 T20287 T20285 arg2Of mice,or
R16049 T20287 T20286 arg1Of mice,STAT-deficient
R16050 T20290 T20288 arg2Of hr,After
R16051 T20290 T20289 arg1Of hr,48
R16052 T20292 T20293 arg1Of they,were
R16053 T20292 T20294 arg2Of they,injected
R16054 T20294 T20288 arg1Of injected,After
R16055 T20294 T20291 arg1Of injected,","
R16056 T20294 T20293 arg2Of injected,were
R16057 T20294 T20295 arg1Of injected,subcutaneously
R16058 T20294 T20296 arg1Of injected,with
R16059 T20294 T20299 arg1Of injected,with
R16060 T20296 T20298 arg1Of with,or
R16061 T20297 T20296 arg2Of PBS,with
R16062 T20299 T20298 arg2Of with,or
R16063 T20301 T20300 arg1Of protein,OVA
R16064 T20301 T20302 arg1Of protein,(
R16065 T20301 T20306 arg1Of protein,plus
R16066 T20304 T20302 arg2Of mg,(
R16067 T20304 T20303 arg1Of mg,5
R16068 T20305 T20302 arg3Of ),(
R16069 T20306 T20299 arg2Of plus,with
R16070 T20307 T20306 arg2Of LPS,plus
R16071 T20307 T20308 arg1Of LPS,(
R16072 T20310 T20308 arg2Of μg,(
R16073 T20310 T20309 arg1Of μg,5
R16074 T20311 T20308 arg3Of ),(
R16075 T20315 T20312 arg1Of nodes,The
R16076 T20315 T20313 arg1Of nodes,inguinal
R16077 T20315 T20314 arg1Of nodes,lymph
R16078 T20315 T20316 arg1Of nodes,were
R16079 T20315 T20317 arg2Of nodes,removed
R16080 T20317 T20316 arg2Of removed,were
R16081 T20317 T20319 arg1Of removed,hr
R16082 T20317 T20320 arg1Of removed,later
R16083 T20319 T20318 arg1Of hr,48
R16084 T20323 T20321 arg1Of suspension,A
R16085 T20323 T20322 arg1Of suspension,single-cell
R16086 T20323 T20324 arg1Of suspension,(
R16087 T20323 T20330 arg1Of suspension,was
R16088 T20323 T20331 arg2Of suspension,restimulated
R16089 T20328 T20324 arg2Of cells,(
R16090 T20328 T20325 arg1Of cells,1
R16091 T20328 T20326 arg1Of cells,×
R16092 T20328 T20327 arg1Of cells,106
R16093 T20329 T20324 arg3Of ),(
R16094 T20331 T20330 arg2Of restimulated,was
R16095 T20331 T20332 arg1Of restimulated,for
R16096 T20331 T20346 arg1Of restimulated,with
R16097 T20332 T20345 arg1Of for,and
R16098 T20333 T20334 arg1Of 24,or
R16099 T20335 T20334 arg2Of 48,or
R161 T253 T252 arg1Of and,","
R16100 T20336 T20332 arg2Of hr,for
R16101 T20336 T20333 arg1Of hr,24
R16102 T20336 T20335 arg1Of hr,48
R16103 T20336 T20337 arg1Of hr,with
R16104 T20339 T20338 arg1Of μM,1
R16105 T20339 T20340 arg1Of μM,or
R16106 T20340 T20337 arg2Of or,with
R16107 T20342 T20340 arg2Of μM,or
R16108 T20342 T20341 arg1Of μM,3
R16109 T20342 T20343 arg1Of μM,of
R16110 T20344 T20343 arg2Of OVA,of
R16111 T20346 T20345 arg2Of with,and
R16112 T20347 T20346 arg2Of BrefeldinA,with
R16113 T20347 T20348 arg1Of BrefeldinA,for
R16114 T20352 T20348 arg2Of hr,for
R16115 T20352 T20349 arg1Of hr,the
R16116 T20352 T20350 arg1Of hr,last
R16117 T20352 T20351 arg1Of hr,6
R16118 T20353 T20354 arg1Of Half,of
R16119 T20353 T20357 arg1Of Half,was
R16120 T20353 T20358 arg2Of Half,removed
R16121 T20356 T20354 arg2Of supernatant,of
R16122 T20356 T20355 arg1Of supernatant,the
R16123 T20358 T20357 arg2Of removed,was
R16124 T20358 T20359 arg1Of removed,before
R16125 T20358 T20364 arg1Of removed,for
R16126 T20361 T20359 arg2Of addition,before
R16127 T20361 T20360 arg1Of addition,the
R16128 T20361 T20362 arg1Of addition,of
R16129 T20363 T20362 arg2Of BrefeldinA,of
R16130 T20365 T20364 arg2Of use,for
R16131 T20365 T20366 arg1Of use,in
R16132 T20369 T20366 arg2Of assay,in
R16133 T20369 T20367 arg1Of assay,an
R16134 T20369 T20368 arg1Of assay,ELISA
R16135 T20371 T20370 arg1Of cells,The
R16136 T20371 T20372 arg1Of cells,were
R16137 T20371 T20373 arg2Of cells,fixed
R16138 T20371 T20375 arg2Of cells,stained
R16139 T20373 T20374 arg1Of fixed,and
R16140 T20374 T20372 arg2Of and,were
R16141 T20375 T20374 arg2Of stained,and
R16142 T20375 T20376 arg1Of stained,as
R16143 T20376 T20377 arg1Of as,before
R16144 T20379 T20378 arg1Of positive,Those
R16145 T20379 T20380 arg1Of positive,for
R16146 T20379 T20383 arg1Of positive,for
R16147 T20379 T20385 arg1Of positive,were
R16148 T20379 T20386 arg2Of positive,gated
R16149 T20380 T20382 arg1Of for,and
R16150 T20381 T20380 arg2Of KJ1-26-Bio,for
R16151 T20383 T20382 arg2Of for,and
R16152 T20384 T20383 arg2Of CD4-PerCP,for
R16153 T20386 T20385 arg2Of gated,were
R16154 T20386 T20388 arg1Of gated,and
R16155 T20388 T20387 arg1Of and,","
R16156 T20389 T20390 arg1Of IFN-γ,and
R16157 T20391 T20390 arg2Of IL-10,and
R16158 T20392 T20389 arg1Of staining,IFN-γ
R16159 T20392 T20391 arg1Of staining,IL-10
R16160 T20392 T20393 arg1Of staining,was
R16161 T20392 T20394 arg2Of staining,examined
R16162 T20392 T20399 arg2Of staining,analyzed
R16163 T20394 T20395 arg1Of examined,for
R16164 T20394 T20398 arg1Of examined,and
R16165 T20397 T20395 arg2Of population,for
R16166 T20397 T20396 arg1Of population,this
R16167 T20398 T20388 arg2Of and,and
R16168 T20398 T20393 arg2Of and,was
R16169 T20399 T20398 arg2Of analyzed,and
R16170 T20399 T20400 arg1Of analyzed,as
R16171 T20400 T20401 arg1Of as,before
R162 T256 T254 arg1Of action,continued
R163 T256 T255 arg1Of action,IL-12
R16341 T20636 T20634 arg1Of RT-PCR,Real-Time
R16342 T20636 T20635 arg1Of RT-PCR,Quantitative
R16343 T20637 T20638 arg1Of Cells,were
R16344 T20637 T20639 arg2Of Cells,harvested
R16345 T20637 T20641 arg2Of Cells,restimulated
R16346 T20637 T20663 arg2Of Cells,lysed
R16347 T20639 T20640 arg1Of harvested,and
R16348 T20640 T20638 arg2Of and,were
R16349 T20641 T20642 arg1Of restimulated,in
R16350 T20641 T20658 arg1Of restimulated,for
R16351 T20641 T20661 arg1Of restimulated,or
R16352 T20642 T20643 arg1Of in,the
R16353 T20642 T20645 arg1Of in,of
R16354 T20644 T20642 arg2Of presence,in
R16355 T20647 T20646 arg2Of anti-CD3,immobilized
R16356 T20647 T20648 arg1Of anti-CD3,(
R16357 T20647 T20652 arg1Of anti-CD3,plus
R16358 T20650 T20648 arg2Of μg/ml,(
R16359 T20650 T20649 arg1Of μg/ml,2
R16360 T20651 T20648 arg3Of ),(
R16361 T20652 T20642 arg3Of plus,in
R16362 T20653 T20652 arg2Of anti-CD28,plus
R16363 T20653 T20654 arg1Of anti-CD28,(
R16364 T20656 T20654 arg2Of μg/ml,(
R16365 T20656 T20655 arg1Of μg/ml,2
R16366 T20657 T20654 arg3Of ),(
R16367 T20660 T20658 arg2Of hr,for
R16368 T20660 T20659 arg1Of hr,3
R16369 T20661 T20640 arg2Of or,and
R16370 T20663 T20661 arg2Of lysed,or
R16371 T20663 T20662 arg1Of lysed,immediately
R16372 T20664 T20665 arg1Of RNA,was
R16373 T20664 T20666 arg2Of RNA,extracted
R16374 T20666 T20665 arg2Of extracted,was
R16375 T20666 T20667 arg1Of extracted,and
R16376 T20668 T20669 arg1Of reverse-transcribed,and
R16377 T20669 T20671 arg1Of and,was
R16378 T20669 T20672 arg2Of and,analyzed
R16379 T20670 T20669 arg2Of cDNA,and
R16380 T20672 T20667 arg2Of analyzed,and
R16381 T20672 T20671 arg2Of analyzed,was
R16382 T20672 T20673 arg1Of analyzed,for
R16383 T20675 T20673 arg2Of expression,for
R16384 T20675 T20674 arg1Of expression,the
R16385 T20675 T20676 arg1Of expression,of
R16386 T20677 T20678 arg1Of cytokines,and
R16387 T20678 T20676 arg2Of and,of
R16388 T20678 T20681 arg1Of and,by
R16389 T20680 T20678 arg2Of factors,and
R16390 T20680 T20679 arg1Of factors,transcription
R16391 T20684 T20681 arg2Of assay,by
R16392 T20684 T20682 arg1Of assay,real-time
R16393 T20684 T20683 arg1Of assay,PCR
R16394 T20684 T20685 arg1Of assay,as
R16395 T20685 T20686 arg1Of as,before
R16396 T20685 T20687 arg1Of as,(
R16397 T20689 T20687 arg2Of et al.,(
R16398 T20689 T20688 arg1Of et al.,Shoemaker
R16399 T20689 T20690 arg1Of et al.,","
R164 T256 T257 arg1Of action,and
R16400 T20691 T20690 arg2Of 2006,","
R16401 T20692 T20687 arg3Of ),(
R16402 T20696 T20693 arg1Of expression,Target
R16403 T20696 T20694 arg1Of expression,gene
R16404 T20696 T20695 arg1Of expression,mRNA
R16405 T20696 T20697 arg1Of expression,was
R16406 T20696 T20698 arg2Of expression,quantified
R16407 T20696 T20716 arg1Of expression,normalized
R16408 T20698 T20697 arg2Of quantified,was
R16409 T20698 T20700 arg1Of quantified,with
R16410 T20698 T20708 arg1Of quantified,with
R16411 T20698 T20715 arg1Of quantified,and
R16412 T20700 T20699 arg1Of with,either
R16413 T20700 T20707 arg1Of with,or
R16414 T20702 T20700 arg2Of Green,with
R16415 T20702 T20701 arg1Of Green,SYBR
R16416 T20702 T20703 arg1Of Green,(
R16417 T20705 T20703 arg2Of Biosystems,(
R16418 T20705 T20704 arg1Of Biosystems,Applied
R16419 T20706 T20703 arg3Of ),(
R16420 T20708 T20707 arg2Of with,or
R16421 T20710 T20708 arg2Of Mix,with
R16422 T20710 T20709 arg1Of Mix,Master
R16423 T20710 T20711 arg1Of Mix,(
R16424 T20713 T20711 arg2Of Biosystems,(
R16425 T20713 T20712 arg1Of Biosystems,Applied
R16426 T20714 T20711 arg3Of ),(
R16427 T20716 T20715 arg2Of normalized,and
R16428 T20716 T20717 arg1Of normalized,to
R16429 T20716 T20723 arg1Of normalized,","
R16430 T20716 T20724 arg1Of normalized,respectively
R16431 T20718 T20719 arg1Of ubiquitin,or
R16432 T20720 T20719 arg2Of HPRT,or
R16433 T20722 T20717 arg2Of levels,to
R16434 T20722 T20718 arg1Of levels,ubiquitin
R16435 T20722 T20720 arg1Of levels,HPRT
R16436 T20722 T20721 arg1Of levels,mRNA
R165 T257 T261 arg1Of and,were
R16542 T20874 T20872 arg2Of T cells,Differentiated
R16543 T20874 T20873 arg1Of T cells,CD4+
R16544 T20874 T20875 arg1Of T cells,were
R16545 T20874 T20876 arg2Of T cells,rested
R16546 T20874 T20886 arg1Of T cells,restimulated
R16547 T20876 T20875 arg2Of rested,were
R16548 T20876 T20877 arg1Of rested,for
R16549 T20876 T20885 arg1Of rested,and
R16550 T20879 T20877 arg2Of hr,for
R16551 T20879 T20878 arg1Of hr,5
R16552 T20879 T20880 arg1Of hr,in
R16553 T20881 T20882 arg1Of 1,%
R16554 T20884 T20880 arg2Of medium,in
R16555 T20884 T20881 arg1Of medium,1
R16556 T20884 T20883 arg1Of medium,FCS-containing
R16557 T20886 T20885 arg2Of restimulated,and
R16558 T20886 T20887 arg1Of restimulated,as
R16559 T20888 T20887 arg2Of described,as
R16560 T20888 T20889 arg1Of described,for
R16561 T20891 T20889 arg2Of experiments,for
R16562 T20891 T20890 arg1Of experiments,specific
R16563 T20893 T20892 arg1Of lysates,Cell
R16564 T20893 T20894 arg1Of lysates,were
R16565 T20893 T20895 arg2Of lysates,prepared
R16566 T20895 T20894 arg2Of prepared,were
R16567 T20898 T20897 arg1Of amounts,equal
R16568 T20898 T20899 arg1Of amounts,of
R16569 T20898 T20901 arg1Of amounts,were
R16570 T20898 T20902 arg2Of amounts,separated
R16571 T20900 T20899 arg2Of protein,of
R16572 T20902 T20901 arg2Of separated,were
R16573 T20902 T20906 arg1Of separated,and
R16574 T20904 T20902 arg1Of SDS-PAGE,separated
R16575 T20904 T20903 arg2Of SDS-PAGE,by
R16576 T20906 T20894 modOf and,were
R16577 T20906 T20896 arg1Of and,","
R16578 T20906 T20905 arg1Of and,","
R16579 T20907 T20908 arg1Of phosphorylated,or
R16580 T20909 T20908 arg2Of total,or
R16581 T20910 T20911 arg1Of ERK,and
R16582 T20911 T20907 arg1Of and,phosphorylated
R16583 T20911 T20909 arg1Of and,total
R16584 T20911 T20913 arg1Of and,were
R16585 T20911 T20914 arg2Of and,detected
R16586 T20912 T20911 arg2Of actin,and
R16587 T20914 T20906 arg2Of detected,and
R16588 T20914 T20913 arg2Of detected,were
R16589 T20914 T20915 arg1Of detected,as
R16590 T20916 T20915 arg2Of described,as
R16591 T20916 T20917 arg1Of described,before
R16592 T20920 T20917 arg2Of et al.,before
R16593 T20920 T20918 arg2Of et al.,(
R16594 T20920 T20919 arg1Of et al.,Beinke
R16595 T20920 T20921 arg1Of et al.,","
R16596 T20922 T20921 arg2Of 2004,","
R16597 T20923 T20918 arg3Of ),(
R166 T257 T262 arg2Of and,required
R167 T260 T257 arg2Of signaling,and
R168 T260 T258 arg1Of signaling,high-dose
R169 T260 T259 arg1Of signaling,TCR
R170 T262 T253 arg2Of required,and
R171 T262 T261 arg2Of required,were
R172 T262 T263 arg1Of required,for
R173 T265 T266 arg1Of development,and
R174 T266 T263 arg2Of and,for
R175 T266 T264 arg1Of and,the
R176 T266 T268 arg1Of and,of
R177 T267 T266 arg2Of maintenance,and
R178 T271 T268 arg2Of cells,of
R179 T271 T269 arg1Of cells,IL-10-producing
R180 T271 T270 arg1Of cells,Th1
R181 T273 T274 arg1Of Th1,","
R182 T274 T277 arg1Of ",",and
R183 T275 T274 arg2Of Th2,","
R184 T277 T276 arg1Of and,","
R185 T278 T277 arg2Of Th17,and
R186 T279 T273 arg1Of cells,Th1
R187 T279 T275 arg1Of cells,Th2
R188 T279 T278 arg1Of cells,Th17
R189 T279 T280 arg1Of cells,require
R190 T280 T272 arg2Of require,Although
R191 T282 T280 arg2Of activation,require
R192 T282 T281 arg1Of activation,the
R193 T282 T283 arg1Of activation,of
R194 T282 T286 arg1Of activation,for
R195 T285 T283 arg2Of STATs,of
R196 T285 T284 arg1Of STATs,distinct
R197 T288 T286 arg2Of differentiation,for
R198 T288 T287 arg1Of differentiation,their
R199 T288 T289 arg1Of differentiation,","
R200 T290 T291 arg1Of activation,of
R201 T290 T293 arg1Of activation,and
R202 T292 T291 arg2Of ERK1,of
R203 T293 T289 arg2Of and,","
R204 T293 T298 arg1Of and,for
R205 T297 T293 arg2Of requirement,and
R206 T297 T294 arg1Of requirement,ERK2
R207 T297 T295 arg1Of requirement,was a
R208 T297 T296 arg1Of requirement,common
R209 T299 T298 arg2Of production,for
R210 T299 T300 arg1Of production,of
R211 T299 T302 arg1Of production,by
R212 T301 T300 arg2Of IL-10,of
R213 T306 T302 arg2Of subsets,by
R214 T306 T303 arg1Of subsets,all
R215 T306 T304 arg1Of subsets,Th
R216 T306 T305 arg1Of subsets,cell
R217 T308 T307 arg1Of expression,IL-10
R218 T308 T310 arg1Of expression,correlated
R219 T310 T309 arg1Of correlated,also
R2199 T2978 T2979 arg1Of IL-12,and
R220 T310 T311 arg1Of correlated,with
R2200 T2979 T2984 arg1Of and,Induce
R2201 T2981 T2979 arg2Of Doses,and
R2202 T2981 T2980 arg1Of Doses,High
R2203 T2981 T2982 arg1Of Doses,of
R2204 T2983 T2982 arg2Of Antigen,of
R2205 T2986 T2984 arg2Of Development,Induce
R2206 T2986 T2985 arg1Of Development,the
R2207 T2986 T2987 arg1Of Development,of
R2208 T2989 T2987 arg2Of Cells,of
R2209 T2989 T2988 arg1Of Cells,Th1
R221 T313 T311 arg2Of expression,with
R2210 T2989 T2990 arg1Of Cells,Producing
R2211 T2991 T2990 arg2Of IL-10,Producing
R2212 T2993 T2992 arg1Of study,To
R2213 T2995 T2993 arg2Of differentiation,study
R2214 T2995 T2994 arg1Of differentiation,the
R2215 T2995 T2996 arg1Of differentiation,of
R2216 T2998 T2996 arg2Of cells,of
R2217 T2998 T2997 arg1Of cells,Th1
R2218 T2998 T2999 arg1Of cells,coproducing
R2219 T3000 T3001 arg1Of IFN-γ,and
R222 T313 T312 arg1Of expression,c-maf
R2220 T3001 T2999 arg2Of and,coproducing
R2221 T3002 T3001 arg2Of IL-10,and
R2222 T3004 T2993 arg1Of we,study
R2223 T3004 T3005 arg1Of we,cultured
R2224 T3005 T2992 modOf cultured,To
R2225 T3005 T3003 arg1Of cultured,","
R2226 T3005 T3012 arg1Of cultured,with
R2227 T3009 T3007 arg1Of naive,TCR-transgenic
R2228 T3009 T3008 arg1Of naive,DO11.10
R2229 T3011 T3005 arg2Of T cells,cultured
R223 T315 T314 arg2Of having,Despite
R2230 T3011 T3006 arg2Of T cells,purified
R2231 T3011 T3009 arg1Of T cells,naive
R2232 T3011 T3010 arg1Of T cells,CD4+
R2233 T3014 T3012 arg2Of DCs,with
R2234 T3014 T3013 arg2Of DCs,purified
R2235 T3014 T3015 arg1Of DCs,as
R2236 T3016 T3017 arg1Of APCs,and
R2237 T3017 T3015 arg2Of and,as
R2238 T3019 T3017 arg2Of doses,and
R2239 T3019 T3018 arg1Of doses,increasing
R224 T315 T318 arg1Of having,in
R2240 T3019 T3020 arg1Of doses,of
R2241 T3022 T3020 arg2Of peptide,of
R2242 T3022 T3021 arg1Of peptide,ovalbumin
R2243 T3022 T3023 arg1Of peptide,323-339
R2244 T3022 T3024 arg1Of peptide,(
R2245 T3025 T3024 arg2Of OVA,(
R2246 T3026 T3024 arg3Of ),(
R2247 T3027 T3028 arg1Of Culture,with
R2248 T3027 T3033 arg1Of Culture,for
R2249 T3027 T3036 arg1Of Culture,gave
R225 T317 T315 arg2Of functions,having
R2250 T3030 T3028 arg2Of doses,with
R2251 T3030 T3029 arg1Of doses,high
R2252 T3030 T3031 arg1Of doses,of
R2253 T3032 T3031 arg2Of antigen,of
R2254 T3035 T3033 arg2Of days,for
R2255 T3035 T3034 arg1Of days,7
R2256 T3037 T3036 arg3Of rise,gave
R2257 T3040 T3039 arg1Of cells,Th1
R2258 T3040 T3041 arg1Of cells,expressing
R2259 T3040 T3045 arg1Of cells,(
R226 T317 T316 arg1Of functions,distinct
R2260 T3040 T3057 arg1Of cells,but
R2261 T3041 T3043 arg1Of expressing,upon
R2262 T3042 T3041 arg2Of IFN-γ,expressing
R2263 T3044 T3043 arg2Of restimulation,upon
R2264 T3047 T3045 arg2Of et al.,(
R2265 T3047 T3046 arg1Of et al.,Constant
R2266 T3047 T3048 arg1Of et al.,","
R2267 T3047 T3050 arg1Of et al.,;
R2268 T3049 T3048 arg2Of 1995,","
R2269 T3051 T3050 arg2Of Hosken,;
R227 T319 T318 arg2Of protection,in
R2270 T3051 T3052 arg1Of Hosken,et al.
R2271 T3051 T3053 arg1Of Hosken,","
R2272 T3054 T3053 arg2Of 1995,","
R2273 T3055 T3045 arg3Of ),(
R2274 T3057 T3036 arg2Of but,gave
R2275 T3057 T3038 arg2Of but,to
R2276 T3057 T3056 arg1Of but,","
R2277 T3059 T3057 arg2Of IL-10,but
R2278 T3059 T3058 arg1Of IL-10,not
R2279 T3059 T3060 arg1Of IL-10,(
R228 T319 T320 arg1Of protection,against
R2280 T3063 T3060 arg2Of online,(
R2281 T3063 T3061 arg1Of online,Figure S1A
R2282 T3063 T3062 arg1Of online,available
R2283 T3064 T3060 arg3Of ),(
R2284 T3065 T3066 arg1Of Culture,with
R2285 T3065 T3074 arg1Of Culture,led
R2286 T3069 T3066 arg2Of doses,with
R2287 T3069 T3067 arg1Of doses,low
R2288 T3069 T3068 arg1Of doses,antigen
R2289 T3069 T3070 arg1Of doses,under
R229 T321 T320 arg2Of pathogens,against
R2290 T3073 T3070 arg2Of conditions,under
R2291 T3073 T3071 arg1Of conditions,the
R2292 T3073 T3072 arg1Of conditions,same
R2293 T3074 T3075 arg1Of led,to
R2294 T3077 T3075 arg2Of differentiation,to
R2295 T3077 T3076 arg1Of differentiation,the
R2296 T3077 T3078 arg1Of differentiation,of
R2297 T3080 T3078 arg2Of cells,of
R2298 T3080 T3079 arg1Of cells,Th2
R2299 T3080 T3081 arg1Of cells,","
R230 T325 T315 arg1Of cells,having
R2300 T3080 T3082 arg1Of cells,which
R2301 T3080 T3083 arg1Of cells,expressed
R2302 T3083 T3088 arg1Of expressed,upon
R2303 T3085 T3086 arg1Of IL-4,and
R2304 T3086 T3083 arg2Of and,expressed
R2305 T3086 T3084 arg1Of and,both
R2306 T3087 T3086 arg2Of IL-10,and
R2307 T3089 T3088 arg2Of restimulation,upon
R2308 T3089 T3090 arg1Of restimulation,(
R2309 T3091 T3090 arg2Of Figure S1A,(
R231 T325 T323 arg1Of cells,all
R2310 T3092 T3090 arg3Of ),(
R2311 T3093 T3094 arg1Of Culture,of
R2312 T3093 T3098 arg1Of Culture,in
R2313 T3093 T3114 arg1Of Culture,resulted
R2314 T3097 T3094 arg2Of T cells,of
R2315 T3097 T3095 arg1Of T cells,naive
R2316 T3097 T3096 arg1Of T cells,CD4+
R2317 T3101 T3098 arg2Of system,in
R2318 T3101 T3099 arg1Of system,an
R2319 T3101 T3100 arg1Of system,APC-free
R232 T325 T324 arg1Of cells,Th
R2320 T3101 T3102 arg1Of system,by
R2321 T3103 T3102 arg2Of stimulation,by
R2322 T3103 T3104 arg1Of stimulation,with
R2323 T3105 T3106 arg1Of anti-CD3,and
R2324 T3107 T3106 arg2Of anti-CD28,and
R2325 T3108 T3104 arg2Of antibodies,with
R2326 T3108 T3105 arg1Of antibodies,anti-CD3
R2327 T3108 T3107 arg1Of antibodies,anti-CD28
R2328 T3108 T3109 arg1Of antibodies,in
R2329 T3111 T3109 arg2Of presence,in
R233 T325 T326 arg1Of cells,share
R2330 T3111 T3110 arg1Of presence,the
R2331 T3111 T3112 arg1Of presence,of
R2332 T3113 T3112 arg2Of IL-12,of
R2333 T3114 T3115 arg1Of resulted,in
R2334 T3118 T3115 arg2Of cells,in
R2335 T3118 T3116 arg1Of cells,IFN-γ-producing
R2336 T3118 T3117 arg1Of cells,Th1
R2337 T3118 T3122 arg2Of cells,of
R2338 T3118 T3123 arg1Of cells,which
R2339 T3121 T3120 arg1Of proportion,a
R234 T326 T314 arg1Of share,Despite
R2340 T3121 T3122 arg1Of proportion,of
R2341 T3121 T3124 arg1Of proportion,coproduced
R2342 T3124 T3119 arg1Of coproduced,","
R2343 T3124 T3126 arg1Of coproduced,","
R2344 T3124 T3127 arg1Of coproduced,as
R2345 T3125 T3124 arg2Of IL-10,coproduced
R2346 T3128 T3127 arg2Of did,as
R2347 T3130 T3128 arg1Of cells,did
R2348 T3130 T3129 arg1Of cells,Th2
R2349 T3130 T3131 arg1Of cells,resulting
R235 T326 T322 arg1Of share,","
R2350 T3131 T3132 arg1Of resulting,from
R2351 T3131 T3134 arg1Of resulting,in
R2352 T3133 T3132 arg2Of culture,from
R2353 T3135 T3134 arg2Of IL-4,in
R2354 T3135 T3136 arg1Of IL-4,(
R2355 T3137 T3136 arg2Of Figure S1B,(
R2356 T3138 T3136 arg3Of ),(
R2357 T3140 T3139 arg1Of investigate,To
R2358 T3143 T3142 arg1Of lack,the
R2359 T3143 T3144 arg1Of lack,of
R236 T329 T326 arg2Of task,share
R2360 T3143 T3150 arg1Of lack,resulted
R2361 T3145 T3144 arg2Of IL-10,of
R2362 T3145 T3146 arg2Of IL-10,produced
R2363 T3149 T3146 arg1Of cells,produced
R2364 T3149 T3147 arg2Of cells,by
R2365 T3149 T3148 arg1Of cells,Th1
R2366 T3150 T3140 arg2Of resulted,investigate
R2367 T3150 T3141 arg1Of resulted,whether
R2368 T3150 T3151 arg1Of resulted,from
R2369 T3152 T3153 arg1Of inhibition,of
R237 T329 T327 arg1Of task,the
R2370 T3152 T3158 arg1Of inhibition,and
R2371 T3155 T3153 arg2Of production,of
R2372 T3155 T3154 arg1Of production,IL-10
R2373 T3155 T3156 arg1Of production,by
R2374 T3157 T3156 arg2Of DCs,by
R2375 T3158 T3151 arg2Of and,from
R2376 T3161 T3159 arg1Of dose,high
R2377 T3161 T3160 arg1Of dose,antigen
R2378 T3161 T3162 arg1Of dose,or
R2379 T3162 T3158 arg2Of or,and
R238 T329 T328 arg1Of task,important
R2380 T3165 T3162 arg2Of IL-12,or
R2381 T3165 T3163 arg1Of IL-12,alternatively
R2382 T3165 T3164 arg2Of IL-12,required
R2383 T3167 T3140 arg1Of we,investigate
R2384 T3167 T3168 arg1Of we,cultured
R2385 T3168 T3139 modOf cultured,To
R2386 T3168 T3166 arg1Of cultured,","
R2387 T3171 T3168 arg2Of T cells,cultured
R2388 T3171 T3169 arg1Of T cells,naive
R2389 T3171 T3170 arg1Of T cells,CD4+
R239 T329 T330 arg1Of task,of
R2390 T3171 T3172 arg1Of T cells,with
R2391 T3174 T3172 arg2Of doses,with
R2392 T3174 T3173 arg1Of doses,increasing
R2393 T3174 T3175 arg1Of doses,of
R2394 T3174 T3177 arg2Of doses,presented
R2395 T3176 T3175 arg2Of antigen,of
R2396 T3177 T3180 arg1Of presented,in
R2397 T3179 T3177 arg1Of DC,presented
R2398 T3179 T3178 arg2Of DC,by
R2399 T3182 T3180 arg2Of presence,in
R240 T331 T330 arg2Of controlling,of
R2400 T3182 T3181 arg1Of presence,the
R2401 T3182 T3183 arg1Of presence,of
R2402 T3184 T3183 arg2Of IL-12,of
R2403 T3187 T3185 arg2Of doses,At
R2404 T3187 T3186 arg1Of doses,low
R2405 T3187 T3188 arg1Of doses,of
R2406 T3189 T3188 arg2Of antigen,of
R2407 T3191 T3192 arg1Of IL-12,abrogated
R2408 T3191 T3199 arg1Of IL-12,induced
R2409 T3192 T3198 arg1Of abrogated,and
R241 T331 T335 arg1Of controlling,by
R2410 T3194 T3192 arg2Of development,abrogated
R2411 T3194 T3193 arg1Of development,the
R2412 T3194 T3195 arg1Of development,of
R2413 T3197 T3195 arg2Of cells,of
R2414 T3197 T3196 arg1Of cells,Th2
R2415 T3198 T3185 arg1Of and,At
R2416 T3198 T3190 arg1Of and,","
R2417 T3199 T3198 arg2Of induced,and
R2418 T3199 T3209 arg1Of induced,","
R2419 T3199 T3210 modOf induced,suggesting
R242 T334 T331 arg2Of responses,controlling
R2420 T3201 T3200 arg1Of expression,IFN-γ
R2421 T3201 T3202 arg1Of expression,but
R2422 T3202 T3199 arg2Of but,induced
R2423 T3202 T3206 arg1Of but,of
R2424 T3205 T3202 arg2Of levels,but
R2425 T3205 T3203 arg1Of levels,only
R2426 T3205 T3204 arg1Of levels,low
R2427 T3208 T3206 arg2Of expression,of
R2428 T3208 T3207 arg1Of expression,IL-10
R2429 T3212 T3214 arg1Of IL-12,se
R243 T334 T332 arg1Of responses,overexuberant
R2430 T3212 T3215 arg1Of IL-12,was
R2431 T3212 T3217 arg1Of IL-12,sufficient
R2432 T3214 T3213 arg1Of se,per
R2433 T3215 T3210 arg2Of was,suggesting
R2434 T3215 T3211 arg1Of was,that
R2435 T3215 T3216 arg1Of was,not
R2436 T3215 T3218 modOf was,to
R2437 T3217 T3215 arg2Of sufficient,was
R2438 T3219 T3218 arg1Of induce,to
R2439 T3219 T3223 arg1Of induce,in
R244 T334 T333 arg1Of responses,immune
R2440 T3222 T3219 arg2Of production,induce
R2441 T3222 T3220 arg1Of production,significant
R2442 T3222 T3221 arg1Of production,IL-10
R2443 T3225 T3223 arg2Of cells,in
R2444 T3225 T3224 arg1Of cells,Th1
R2445 T3225 T3226 arg1Of cells,(
R2446 T3227 T3226 arg2Of Figure 1A,(
R2447 T3228 T3226 arg3Of ),(
R2448 T3234 T3232 arg1Of dose,the
R2449 T3234 T3233 arg1Of dose,antigen
R245 T336 T335 arg2Of means,by
R2450 T3234 T3235 arg1Of dose,was
R2451 T3234 T3236 arg2Of dose,increased
R2452 T3236 T3231 arg2Of increased,as
R2453 T3236 T3235 arg2Of increased,was
R2454 T3239 T3238 arg1Of populations,Th1
R2455 T3239 T3240 arg2Of populations,driven
R2456 T3239 T3244 arg1Of populations,contained
R2457 T3239 T3254 arg1Of populations,produced
R2458 T3240 T3241 arg1Of driven,with
R2459 T3242 T3241 arg2Of IL-12,with
R246 T336 T337 arg1Of means,of
R2460 T3244 T3253 arg1Of contained,and
R2461 T3246 T3244 arg2Of numbers,contained
R2462 T3246 T3245 arg1Of numbers,higher
R2463 T3246 T3247 arg1Of numbers,of
R2464 T3249 T3247 arg2Of cells,of
R2465 T3249 T3248 arg1Of cells,IL-10-producing
R2466 T3249 T3250 arg1Of cells,(
R2467 T3251 T3250 arg2Of Figure 1A,(
R2468 T3252 T3250 arg3Of ),(
R2469 T3253 T3229 arg1Of and,Strikingly
R247 T339 T337 arg2Of production,of
R2470 T3253 T3230 arg1Of and,","
R2471 T3253 T3231 arg1Of and,as
R2472 T3253 T3237 arg1Of and,","
R2473 T3253 T3243 arg1Of and,now
R2474 T3254 T3253 arg2Of produced,and
R2475 T3254 T3258 arg1Of produced,upon
R2476 T3257 T3254 arg2Of protein,produced
R2477 T3257 T3255 arg1Of protein,more
R2478 T3257 T3256 arg1Of protein,IL-10
R2479 T3259 T3258 arg2Of restimulation,upon
R248 T339 T338 arg1Of production,IL-10
R2480 T3259 T3260 arg1Of restimulation,(
R2481 T3262 T3263 arg1Of 1A,and
R2482 T3263 T3260 arg2Of and,(
R2483 T3263 T3261 arg1Of and,Figures
R2484 T3264 T3263 arg2Of 1B,and
R2485 T3265 T3260 arg3Of ),(
R2486 T3269 T3268 arg1Of development,the
R2487 T3269 T3270 arg1Of development,of
R2488 T3269 T3275 arg1Of development,required
R2489 T3272 T3270 arg2Of cells,of
R2490 T3272 T3271 arg1Of cells,Th1
R2491 T3272 T3273 arg1Of cells,producing
R2492 T3274 T3273 arg2Of IL-10,producing
R2493 T3275 T3266 arg1Of required,Thus
R2494 T3275 T3267 arg1Of required,","
R2495 T3277 T3278 arg1Of IL-12,and
R2496 T3278 T3275 arg2Of and,required
R2497 T3278 T3276 arg1Of and,both
R2498 T3280 T3278 arg2Of doses,and
R2499 T3280 T3279 arg1Of doses,high
R2500 T3280 T3281 arg1Of doses,of
R2501 T3282 T3281 arg2Of antigen,of
R2502 T3284 T3283 arg1Of cells,Th1
R2503 T3284 T3285 arg2Of cells,differentiated
R2504 T3285 T3286 modOf differentiated,to
R2505 T3287 T3294 arg1Of produce,and
R2506 T3289 T3287 arg2Of amounts,produce
R2507 T3289 T3288 arg1Of amounts,large
R2508 T3289 T3290 arg1Of amounts,of
R2509 T3291 T3292 arg1Of IL-10,and
R2510 T3292 T3290 arg2Of and,of
R2511 T3293 T3292 arg2Of IFN-γ,and
R2512 T3294 T3286 arg1Of and,to
R2513 T3295 T3294 arg2Of lost,and
R2514 T3296 T3295 arg2Of their capacity,lost
R2515 T3296 T3297 modOf their capacity,to
R2516 T3298 T3297 arg1Of produce,to
R2517 T3299 T3298 arg2Of IL-2,produce
R2518 T3299 T3300 arg1Of IL-2,(
R2519 T3301 T3300 arg2Of Figure 1B,(
R2520 T3302 T3300 arg3Of ),(
R2521 T3305 T3304 arg1Of presence,the
R2522 T3305 T3306 arg1Of presence,of
R2523 T3305 T3308 arg1Of presence,reduced
R2524 T3307 T3306 arg2Of IL-12,of
R2525 T3308 T3314 arg1Of reduced,at
R2526 T3308 T3325 arg1Of reduced,and
R2527 T3310 T3308 arg2Of proliferation,reduced
R2528 T3310 T3309 arg1Of proliferation,the
R2529 T3310 T3311 arg1Of proliferation,of
R2530 T3313 T3311 arg2Of T cells,of
R2531 T3313 T3312 arg1Of T cells,CD4+
R2532 T3319 T3314 arg2Of doses,at
R2533 T3319 T3315 arg1Of doses,both
R2534 T3319 T3316 arg1Of doses,high
R2535 T3319 T3317 arg1Of doses,and low
R2536 T3319 T3318 arg1Of doses,antigen
R2537 T3319 T3320 arg1Of doses,(
R2538 T3322 T3320 arg2Of S1,(
R2539 T3322 T3321 arg1Of S1,Table
R2540 T3323 T3320 arg3Of ),(
R2541 T3325 T3303 arg2Of and,Because
R2542 T3325 T3324 arg1Of and,","
R2543 T3328 T3326 arg1Of former,only
R2544 T3328 T3327 arg1Of former,the
R2545 T3328 T3329 arg1Of former,showed
R2546 T3329 T3325 arg2Of showed,and
R2547 T3331 T3329 arg2Of production,showed
R2548 T3331 T3330 arg1Of production,IL-10
R2549 T3331 T3332 arg1Of production,","
R2550 T3334 T3332 arg2Of development,","
R2551 T3334 T3333 arg1Of development,the
R2552 T3334 T3335 arg1Of development,of
R2553 T3338 T3335 arg2Of cells is,of
R2554 T3338 T3336 arg1Of cells is,high
R2555 T3338 T3337 arg1Of cells is,IL-10-producing
R2556 T3338 T3342 arg1Of cells is,related
R2557 T3340 T3339 arg1Of likely,most
R2558 T3342 T3340 arg1Of related,likely
R2559 T3342 T3341 arg1Of related,not
R2560 T3342 T3343 arg1Of related,to
R2561 T3345 T3343 arg2Of IL-2,to
R2562 T3345 T3344 arg1Of IL-2,limited
R2563 T3348 T3346 arg1Of T cells,Naive
R2564 T3348 T3347 arg1Of T cells,CD4+
R2565 T3348 T3349 arg1Of T cells,from
R2566 T3348 T3358 arg1Of T cells,","
R2567 T3348 T3359 arg2Of T cells,cultured
R2568 T3348 T3372 arg1Of T cells,resulted
R2569 T3354 T3353 arg2Of Rag1,(
R2570 T3355 T3353 arg3Of ),(
R2571 T3357 T3349 arg2Of animals,from
R2572 T3357 T3350 arg1Of animals,DO11.10/recombination-activating
R2573 T3357 T3351 arg1Of animals,gene
R2574 T3357 T3352 arg1Of animals,1
R2575 T3357 T3353 arg1Of animals,(
R2576 T3357 T3356 arg1Of animals,-deficient
R2577 T3359 T3360 arg1Of cultured,with
R2578 T3362 T3360 arg2Of doses,with
R2579 T3362 T3361 arg1Of doses,high
R2580 T3362 T3363 arg1Of doses,of
R2581 T3362 T3365 arg1Of doses,in
R2582 T3364 T3363 arg2Of antigen,of
R2583 T3367 T3365 arg2Of presence,in
R2584 T3367 T3366 arg1Of presence,the
R2585 T3367 T3368 arg1Of presence,of
R2586 T3369 T3368 arg2Of IL-12,of
R2587 T3372 T3370 arg1Of resulted,","
R2588 T3372 T3371 arg1Of resulted,also
R2589 T3372 T3373 arg1Of resulted,in
R2590 T3372 T3379 arg1Of resulted,","
R2591 T3372 T3380 modOf resulted,showing
R2592 T3375 T3373 arg2Of expression,in
R2593 T3375 T3374 arg1Of expression,IL-10
R2594 T3375 T3376 arg1Of expression,by
R2595 T3378 T3376 arg2Of cells,by
R2596 T3378 T3377 arg1Of cells,Th1
R2597 T3383 T3382 arg1Of expression,this
R2598 T3383 T3384 arg1Of expression,was
R2599 T3383 T3386 arg1Of expression,dependent
R2600 T3384 T3380 arg2Of was,showing
R2601 T3384 T3381 arg1Of was,that
R2602 T3384 T3385 arg1Of was,not
R2603 T3386 T3384 arg2Of dependent,was
R2604 T3386 T3387 arg1Of dependent,on
R2605 T3389 T3387 arg2Of presence,on
R2606 T3389 T3388 arg1Of presence,the
R2607 T3389 T3390 arg1Of presence,of
R2608 T3391 T3392 arg1Of effector,or
R2609 T3393 T3392 arg2Of memory,or
R2610 T3394 T3391 arg1Of T cells,effector
R2611 T3394 T3393 arg1Of T cells,memory
R2612 T3394 T3395 arg1Of T cells,or
R2613 T3395 T3390 arg2Of or,of
R2614 T3397 T3395 arg2Of cells,or
R2615 T3397 T3396 arg1Of cells,Treg
R2616 T3397 T3398 arg1Of cells,(
R2617 T3399 T3398 arg2Of Figure S2,(
R2618 T3400 T3398 arg3Of ),(
R2619 T3402 T3403 arg1Of it,has
R2620 T3402 T3404 arg1Of it,been
R2621 T3402 T3405 arg2Of it,suggested
R2622 T3405 T3401 arg2Of suggested,Although
R2623 T3405 T3403 arg2Of suggested,has
R2624 T3405 T3404 arg2Of suggested,been
R2625 T3407 T3408 arg1Of TGF-β,can
R2626 T3407 T3409 arg1Of TGF-β,induce
R2627 T3409 T3405 arg3Of induce,suggested
R2628 T3409 T3406 arg1Of induce,that
R2629 T3409 T3408 arg2Of induce,can
R2630 T3410 T3409 arg2Of IL-10,induce
R2631 T3410 T3411 arg1Of IL-10,in
R2632 T3413 T3411 arg2Of T cells,in
R2633 T3413 T3412 arg1Of T cells,CD4+
R2634 T3413 T3414 arg1Of T cells,(
R2635 T3416 T3415 arg1Of et al.,Kitani
R2636 T3416 T3417 arg1Of et al.,","
R2637 T3416 T3419 arg1Of et al.,;
R2638 T3418 T3417 arg2Of 2003,","
R2639 T3419 T3414 arg2Of ;,(
R2640 T3420 T3419 arg2Of Schiott,;
R2641 T3420 T3421 arg1Of Schiott,et al.
R2642 T3420 T3422 arg1Of Schiott,","
R2643 T3423 T3422 arg2Of 2000,","
R2644 T3424 T3414 arg3Of ),(
R2645 T3426 T3427 arg1Of we,found
R2646 T3427 T3401 arg1Of found,Although
R2647 T3427 T3425 arg1Of found,","
R2648 T3431 T3432 arg1Of Th1,and
R2649 T3433 T3432 arg2Of Th2,and
R2650 T3434 T3429 arg2Of cells,in
R2651 T3434 T3430 arg1Of cells,developing
R2652 T3434 T3431 arg1Of cells,Th1
R2653 T3434 T3433 arg1Of cells,Th2
R2654 T3435 T3436 arg1Of this,was
R2655 T3436 T3427 arg2Of was,found
R2656 T3436 T3428 arg1Of was,that
R2657 T3436 T3429 arg1Of was,in
R2658 T3436 T3437 arg1Of was,not
R2659 T3439 T3436 arg2Of case,was
R2660 T3439 T3438 arg1Of case,the
R2661 T3439 T3440 arg1Of case,(
R2662 T3441 T3440 arg2Of data,(
R2663 T3441 T3443 arg2Of data,shown
R2664 T3443 T3442 arg1Of shown,not
R2665 T3444 T3440 arg3Of ),(
R2666 T3446 T3445 arg2Of fact,In
R2667 T3448 T3449 arg1Of neutralization,of
R2668 T3448 T3451 arg1Of neutralization,led
R2669 T3450 T3449 arg2Of TGF-β,of
R2670 T3451 T3445 arg1Of led,In
R2671 T3451 T3447 arg1Of led,","
R2672 T3451 T3452 arg1Of led,to
R2673 T3455 T3452 arg2Of production,to
R2674 T3455 T3453 arg2Of production,increased
R2675 T3455 T3454 arg1Of production,IL-10
R2676 T3455 T3456 arg1Of production,by
R2677 T3459 T3456 arg2Of subsets,by
R2678 T3459 T3457 arg1Of subsets,both
R2679 T3459 T3458 arg1Of subsets,T cell
R2680 T3459 T3460 arg1Of subsets,(
R2681 T3461 T3460 arg2Of Figure S3,(
R2682 T3462 T3460 arg3Of ),(
R2683 T3466 T3465 arg1Of development,the
R2684 T3466 T3467 arg1Of development,of
R2685 T3466 T3472 arg1Of development,depended
R2686 T3470 T3467 arg2Of cells,of
R2687 T3470 T3468 arg1Of cells,IL-10-producing
R2688 T3470 T3469 arg1Of cells,Th1
R2689 T3472 T3463 arg1Of depended,Thus
R2690 T3472 T3464 arg1Of depended,","
R2691 T3472 T3471 arg1Of depended,only
R2692 T3472 T3473 arg1Of depended,on
R2693 T3472 T3485 arg1Of depended,on
R2694 T3472 T3495 arg1Of depended,on
R2695 T3473 T3483 arg1Of on,and
R2696 T3475 T3473 arg2Of presence,on
R2697 T3475 T3474 arg1Of presence,the
R2698 T3475 T3476 arg1Of presence,of
R2699 T3475 T3478 arg1Of presence,together
R2700 T3477 T3476 arg2Of IL-12,of
R2701 T3478 T3479 arg1Of together,with
R2702 T3482 T3479 arg2Of dose,with
R2703 T3482 T3480 arg1Of dose,high
R2704 T3482 T3481 arg1Of dose,antigen
R2705 T3485 T3494 arg1Of on,or
R2706 T3488 T3485 arg2Of factors,on
R2707 T3488 T3486 arg1Of factors,other
R2708 T3488 T3487 arg1Of factors,soluble
R2709 T3488 T3490 arg1Of factors,as
R2710 T3490 T3489 arg1Of as,such
R2711 T3491 T3492 arg1Of IL-2,or
R2712 T3492 T3490 arg2Of or,as
R2713 T3493 T3492 arg2Of TGF-β,or
R2714 T3494 T3483 arg2Of or,and
R2715 T3494 T3484 arg1Of or,not
R2716 T3495 T3494 arg2Of on,or
R2717 T3497 T3495 arg2Of presence,on
R2718 T3497 T3496 arg1Of presence,the
R2719 T3497 T3498 arg1Of presence,of
R2720 T3501 T3498 arg2Of types,of
R2721 T3501 T3499 arg1Of types,other
R2722 T3501 T3500 arg1Of types,T cell
R3767 T5037 T5036 arg1Of Production,IL-10
R3768 T5037 T5038 arg1Of Production,by
R3769 T5037 T5041 arg1Of Production,Is
R3770 T5037 T5042 arg1Of Production,Dependent
R3771 T5040 T5038 arg2Of Cells,by
R3772 T5040 T5039 arg1Of Cells,Th1
R3773 T5042 T5041 arg2Of Dependent,Is
R3774 T5042 T5043 arg1Of Dependent,on
R3775 T5042 T5047 arg1Of Dependent,on
R3776 T5043 T5045 arg1Of on,but
R3777 T5044 T5043 arg2Of STAT4,on
R3778 T5047 T5045 arg2Of on,but
R3779 T5047 T5046 arg1Of on,Not
R3780 T5048 T5049 arg1Of STAT6,","
R3781 T5049 T5052 arg1Of ",",or
R3782 T5050 T5049 arg2Of IFN-γ,","
R3783 T5052 T5047 arg2Of or,on
R3784 T5052 T5051 arg1Of or,","
R3785 T5054 T5052 arg2Of Signaling,or
R3786 T5054 T5053 arg1Of Signaling,IL-4
R3787 T5057 T5055 arg1Of elucidate,To
R3788 T5057 T5056 arg1Of elucidate,further
R3789 T5059 T5057 arg2Of mechanisms,elucidate
R3790 T5059 T5058 arg1Of mechanisms,the
R3791 T5059 T5060 arg2Of mechanisms,required
R3792 T5060 T5061 arg1Of required,for
R3793 T5063 T5061 arg2Of development,for
R3794 T5063 T5062 arg1Of development,the
R3795 T5063 T5064 arg1Of development,of
R3796 T5066 T5064 arg2Of cells,of
R3797 T5066 T5065 arg1Of cells,Th1
R3798 T5066 T5067 arg1Of cells,producing
R3799 T5068 T5067 arg2Of IL-10,producing
R3800 T5070 T5057 arg1Of we,elucidate
R3801 T5070 T5071 arg1Of we,investigated
R3802 T5071 T5055 modOf investigated,To
R3803 T5071 T5069 arg1Of investigated,","
R3804 T5073 T5071 arg2Of role,investigated
R3805 T5073 T5072 arg1Of role,the
R3806 T5073 T5074 arg1Of role,of
R3807 T5073 T5082 arg2Of role,activated
R3808 T5075 T5074 arg2Of STAT4,of
R3809 T5075 T5076 arg1Of STAT4,","
R3810 T5077 T5076 arg2Of one,","
R3811 T5077 T5078 arg1Of one,of
R3812 T5081 T5078 arg2Of pathways,of
R3813 T5081 T5079 arg1Of pathways,the
R3814 T5081 T5080 arg1Of pathways,signaling
R3815 T5084 T5082 arg1Of IL-12,activated
R3816 T5084 T5083 arg2Of IL-12,by
R3817 T5084 T5085 arg1Of IL-12,(
R3818 T5087 T5085 arg2Of et al.,(
R3819 T5087 T5086 arg1Of et al.,Murphy
R3820 T5087 T5088 arg1Of et al.,","
R3821 T5089 T5088 arg2Of 2000,","
R3822 T5090 T5085 arg3Of ),(
R3823 T5094 T5091 arg1Of T cells,Naive
R3824 T5094 T5092 arg1Of T cells,CD4+
R3825 T5094 T5093 arg1Of T cells,D011.10
R3826 T5094 T5095 arg1Of T cells,deficient
R3827 T5094 T5098 arg1Of T cells,(
R3828 T5094 T5104 arg1Of T cells,were
R3829 T5094 T5105 arg2Of T cells,cultured
R3830 T5095 T5096 arg1Of deficient,in
R3831 T5097 T5096 arg2Of STAT4,in
R3832 T5100 T5098 arg2Of et al.,(
R3833 T5100 T5099 arg1Of et al.,Ouyang
R3834 T5100 T5101 arg1Of et al.,","
R3835 T5102 T5101 arg2Of 1998,","
R3836 T5103 T5098 arg3Of ),(
R3837 T5105 T5104 arg2Of cultured,were
R3838 T5105 T5106 arg1Of cultured,in
R3839 T5108 T5106 arg2Of presence,in
R3840 T5108 T5107 arg1Of presence,the
R3841 T5108 T5109 arg1Of presence,of
R3842 T5110 T5111 arg1Of IL-12,and
R3843 T5111 T5109 arg2Of and,of
R3844 T5112 T5111 arg2Of OVA,and
R3845 T5117 T5115 arg1Of cells,IL-10-producing
R3846 T5117 T5116 arg1Of cells,Th1
R3847 T5117 T5118 arg1Of cells,were
R3848 T5117 T5119 arg2Of cells,differentiated
R3849 T5119 T5113 arg1Of differentiated,Again
R3850 T5119 T5114 arg1Of differentiated,","
R3851 T5119 T5118 arg2Of differentiated,were
R3852 T5119 T5120 arg1Of differentiated,at
R3853 T5119 T5125 arg1Of differentiated,in
R3854 T5124 T5120 arg2Of dose,at
R3855 T5124 T5121 arg1Of dose,the
R3856 T5124 T5122 arg1Of dose,high
R3857 T5124 T5123 arg1Of dose,antigen
R3858 T5127 T5125 arg2Of presence,in
R3859 T5127 T5126 arg1Of presence,the
R3860 T5127 T5128 arg1Of presence,of
R3861 T5127 T5130 arg1Of presence,in
R3862 T5129 T5128 arg2Of IL-12,of
R3863 T5132 T5130 arg2Of T cells,in
R3864 T5132 T5131 arg1Of T cells,DO11.10
R3865 T5132 T5133 arg1Of T cells,(
R3866 T5134 T5133 arg2Of Figure 2A,(
R3867 T5135 T5133 arg3Of ),(
R3868 T5137 T5136 arg2Of contrast,In
R3869 T5139 T5140 arg1Of in,the
R3870 T5139 T5142 arg1Of in,of
R3871 T5141 T5139 arg2Of absence,in
R3872 T5143 T5139 arg3Of STAT4,in
R3873 T5146 T5145 arg1Of percentage,the
R3874 T5146 T5147 arg1Of percentage,of
R3875 T5146 T5151 arg1Of percentage,was
R3876 T5146 T5153 arg2Of percentage,diminished
R3877 T5148 T5147 arg2Of cells,of
R3878 T5148 T5149 arg1Of cells,expressing
R3879 T5150 T5149 arg2Of IFN-γ,expressing
R3880 T5153 T5136 arg1Of diminished,In
R3881 T5153 T5138 arg1Of diminished,","
R3882 T5153 T5139 arg1Of diminished,in
R3883 T5153 T5144 arg1Of diminished,","
R3884 T5153 T5151 arg2Of diminished,was
R3885 T5153 T5152 arg1Of diminished,dramatically
R3886 T5153 T5154 arg1Of diminished,as
R3887 T5155 T5156 arg1Of expected,and
R3888 T5156 T5154 arg2Of and,as
R3889 T5156 T5175 arg1Of and,","
R3890 T5156 T5176 modOf and,suggesting
R3891 T5157 T5156 arg2Of resulted,and
R3892 T5157 T5158 arg1Of resulted,in
R3893 T5160 T5159 arg1Of increase,an
R3894 T5160 T5161 arg1Of increase,in
R3895 T5160 T5169 arg1Of increase,but
R3896 T5163 T5161 arg2Of percentage,in
R3897 T5163 T5162 arg1Of percentage,the
R3898 T5163 T5164 arg1Of percentage,of
R3899 T5165 T5164 arg2Of cells,of
R3900 T5165 T5166 arg1Of cells,expressing
R3901 T5167 T5166 arg2Of IL-4,expressing
R3902 T5169 T5158 arg2Of but,in
R3903 T5169 T5168 arg1Of but,","
R3904 T5169 T5170 arg1Of but,not
R3905 T5171 T5169 arg2Of IL-10,but
R3906 T5171 T5172 arg1Of IL-10,(
R3907 T5173 T5172 arg2Of Figure 2A,(
R3908 T5174 T5172 arg3Of ),(
R3909 T5178 T5179 arg1Of STAT4,contributes
R3910 T5179 T5176 arg2Of contributes,suggesting
R3911 T5179 T5177 arg1Of contributes,that
R3912 T5179 T5180 arg1Of contributes,to
R3913 T5182 T5180 arg2Of expression,to
R3914 T5182 T5181 arg1Of expression,IL-10
R3915 T5182 T5183 arg1Of expression,by
R3916 T5185 T5183 arg2Of cells,by
R3917 T5185 T5184 arg1Of cells,Th1
R3918 T5188 T5187 arg1Of expression,IL-10
R3919 T5188 T5189 arg1Of expression,is
R3920 T5188 T5190 arg2Of expression,associated
R3921 T5190 T5186 arg2Of associated,Because
R3922 T5190 T5189 arg2Of associated,is
R3923 T5190 T5191 arg1Of associated,with
R3924 T5196 T5191 arg2Of phenotype,with
R3925 T5196 T5192 arg1Of phenotype,an
R3926 T5196 T5193 arg1Of phenotype,IL-4-induced
R3927 T5196 T5194 arg1Of phenotype,Th2
R3928 T5196 T5195 arg1Of phenotype,cell
R3929 T5198 T5199 arg1Of we,investigated
R3930 T5199 T5186 arg1Of investigated,Because
R3931 T5199 T5197 arg1Of investigated,","
R3932 T5202 T5201 arg1Of differentiation,the
R3933 T5202 T5203 arg1Of differentiation,of
R3934 T5202 T5208 arg1Of differentiation,depended
R3935 T5207 T5203 arg2Of cells,of
R3936 T5207 T5204 arg1Of cells,the
R3937 T5207 T5205 arg1Of cells,IL-10-producing
R3938 T5207 T5206 arg1Of cells,Th1
R3939 T5208 T5199 arg2Of depended,investigated
R3940 T5208 T5200 arg1Of depended,whether
R3941 T5208 T5209 arg1Of depended,on
R3942 T5208 T5211 arg1Of depended,through
R3943 T5208 T5215 arg1Of depended,via
R3944 T5208 T5218 arg1Of depended,(
R3945 T5210 T5209 arg2Of signaling,on
R3946 T5214 T5211 arg2Of receptor,through
R3947 T5214 T5212 arg1Of receptor,the
R3948 T5214 T5213 arg1Of receptor,IL-4
R3949 T5217 T5215 arg2Of activation,via
R3950 T5217 T5216 arg1Of activation,STAT6
R3951 T5219 T5220 arg1Of Glimcher,and
R3952 T5220 T5218 arg2Of and,(
R3953 T5220 T5222 arg1Of and,","
R3954 T5220 T5224 arg1Of and,;
R3955 T5221 T5220 arg2Of Murphy,and
R3956 T5223 T5222 arg2Of 2000,","
R3957 T5225 T5224 arg2Of Murphy,;
R3958 T5225 T5226 arg1Of Murphy,et al.
R3959 T5225 T5227 arg1Of Murphy,","
R3960 T5228 T5227 arg2Of 2000,","
R3961 T5229 T5218 arg3Of ),(
R3962 T5231 T5230 arg1Of absence,The
R3963 T5231 T5232 arg1Of absence,of
R3964 T5231 T5234 arg1Of absence,did
R3965 T5231 T5236 arg1Of absence,impair
R3966 T5233 T5232 arg2Of STAT6,of
R3967 T5236 T5234 arg2Of impair,did
R3968 T5236 T5235 arg1Of impair,not
R3969 T5238 T5236 arg2Of differentiation,impair
R3970 T5238 T5237 arg1Of differentiation,the
R3971 T5238 T5239 arg1Of differentiation,of
R3972 T5238 T5243 arg1Of differentiation,in
R3973 T5242 T5239 arg2Of cells,of
R3974 T5242 T5240 arg1Of cells,IL-10-producing
R3975 T5242 T5241 arg1Of cells,Th1
R3976 T5245 T5243 arg2Of presence,in
R3977 T5245 T5244 arg1Of presence,the
R3978 T5245 T5246 arg1Of presence,of
R3979 T5247 T5248 arg1Of IL-12,and
R3980 T5248 T5246 arg2Of and,of
R3981 T5248 T5250 arg1Of and,(
R3982 T5249 T5248 arg2Of OVA,and
R3983 T5251 T5250 arg2Of Figure 2A,(
R3984 T5252 T5250 arg3Of ),(
R3985 T5254 T5253 arg2Of fact,In
R3986 T5258 T5256 arg1Of percentage,a
R3987 T5258 T5257 arg1Of percentage,higher
R3988 T5258 T5259 arg1Of percentage,of
R3989 T5258 T5266 arg1Of percentage,produced
R3990 T5261 T5259 arg2Of cells,of
R3991 T5261 T5260 arg1Of cells,STAT6-deficient
R3992 T5261 T5262 arg1Of cells,compared
R3993 T5263 T5262 arg2Of with,compared
R3994 T5265 T5263 arg2Of cells,with
R3995 T5265 T5264 arg1Of cells,WT
R3996 T5266 T5253 arg1Of produced,In
R3997 T5266 T5255 arg1Of produced,","
R3998 T5268 T5269 arg1Of IL-10,and
R3999 T5269 T5266 arg2Of and,produced
R4000 T5269 T5267 arg1Of and,both
R4001 T5269 T5271 arg1Of and,(
R4002 T5269 T5274 arg1Of and,","
R4003 T5269 T5275 arg1Of and,which
R4004 T5269 T5276 arg1Of and,may
R4005 T5269 T5277 arg1Of and,be
R4006 T5270 T5269 arg2Of IFN-γ,and
R4007 T5272 T5271 arg2Of Figure 2A,(
R4008 T5273 T5271 arg3Of ),(
R4009 T5277 T5276 arg2Of be,may
R4010 T5279 T5277 arg2Of result,be
R4011 T5279 T5278 arg1Of result,the
R4012 T5279 T5280 arg1Of result,of
R4013 T5282 T5280 arg2Of loss,of
R4014 T5282 T5281 arg1Of loss,the
R4015 T5282 T5283 arg1Of loss,of
R4016 T5282 T5287 arg1Of loss,over
R4017 T5286 T5283 arg2Of control,of
R4018 T5286 T5284 arg1Of control,Th2
R4019 T5286 T5285 arg1Of control,cell
R4020 T5291 T5287 arg2Of response,over
R4021 T5291 T5288 arg1Of response,a
R4022 T5291 T5289 arg1Of response,Th1
R4023 T5291 T5290 arg1Of response,cell
R4024 T5293 T5292 arg2Of expected,As
R4025 T5295 T5296 arg1Of lack,of
R4026 T5295 T5298 arg1Of lack,abrogated
R4027 T5297 T5296 arg2Of STAT6,of
R4028 T5298 T5292 arg1Of abrogated,As
R4029 T5298 T5294 arg1Of abrogated,","
R4030 T5300 T5301 arg1Of IL-4,and
R4031 T5301 T5298 arg2Of and,abrogated
R4032 T5301 T5299 arg1Of and,both
R4033 T5301 T5304 arg1Of and,by
R4034 T5303 T5301 arg2Of production,and
R4035 T5303 T5302 arg1Of production,IL-10
R4036 T5305 T5304 arg2Of T cells,by
R4037 T5305 T5306 arg2Of T cells,developed
R4038 T5306 T5307 arg1Of developed,with
R4039 T5306 T5310 arg1Of developed,with
R4040 T5307 T5309 arg1Of with,or
R4041 T5308 T5307 arg2Of IL-4,with
R4042 T5310 T5309 arg2Of with,or
R4043 T5313 T5310 arg2Of dose,with
R4044 T5313 T5311 arg1Of dose,low
R4045 T5313 T5312 arg1Of dose,antigen
R4046 T5313 T5314 arg1Of dose,(
R4047 T5316 T5317 arg1Of 2B,and
R4048 T5317 T5314 arg2Of and,(
R4049 T5317 T5315 arg1Of and,Figures
R4050 T5318 T5317 arg2Of 2C,and
R4051 T5319 T5314 arg3Of ),(
R4052 T5322 T5323 arg1Of in,the
R4053 T5322 T5325 arg1Of in,of
R4054 T5324 T5322 arg2Of absence,in
R4055 T5327 T5322 arg3Of signaling,in
R4056 T5327 T5326 arg1Of signaling,STAT4
R4057 T5329 T5330 arg1Of IL-10,and
R4058 T5330 T5333 arg1Of and,by
R4059 T5330 T5336 arg1Of and,was
R4060 T5332 T5330 arg2Of production,and
R4061 T5332 T5331 arg1Of production,IL-4
R4062 T5335 T5333 arg2Of cells,by
R4063 T5335 T5334 arg1Of cells,Th2
R4064 T5336 T5320 arg1Of was,However
R4065 T5336 T5321 arg1Of was,","
R4066 T5336 T5322 arg1Of was,in
R4067 T5336 T5328 arg1Of was,","
R4068 T5338 T5339 arg1Of anything,increased
R4069 T5339 T5336 arg2Of increased,was
R4070 T5339 T5337 arg1Of increased,if
R4071 T5339 T5340 arg1Of increased,(
R4072 T5342 T5343 arg1Of 2B,and
R4073 T5343 T5340 arg2Of and,(
R4074 T5343 T5341 arg1Of and,Figures
R4075 T5344 T5343 arg2Of 2C,and
R4076 T5345 T5340 arg3Of ),(
R4077 T5349 T5348 arg2Of contrast,in
R4078 T5349 T5350 arg1Of contrast,to
R4079 T5351 T5350 arg2Of what,to
R4080 T5351 T5352 arg1Of what,was
R4081 T5351 T5353 arg2Of what,observed
R4082 T5353 T5352 arg2Of observed,was
R4083 T5353 T5354 arg1Of observed,under
R4084 T5356 T5354 arg2Of conditions,under
R4085 T5356 T5355 arg1Of conditions,Th1
R4086 T5359 T5358 arg1Of expression,IL-10
R4087 T5359 T5360 arg1Of expression,by
R4088 T5359 T5363 arg1Of expression,depended
R4089 T5362 T5360 arg2Of cells,by
R4090 T5362 T5361 arg1Of cells,Th2
R4091 T5363 T5346 arg1Of depended,Thus
R4092 T5363 T5347 arg1Of depended,","
R4093 T5363 T5348 arg1Of depended,in
R4094 T5363 T5357 arg1Of depended,","
R4095 T5363 T5364 arg1Of depended,on
R4096 T5363 T5369 arg1Of depended,on
R4097 T5364 T5367 arg1Of on,but
R4098 T5365 T5364 arg2Of STAT6,on
R4099 T5367 T5366 arg1Of but,","
R4100 T5369 T5367 arg2Of on,but
R4101 T5369 T5368 arg1Of on,not
R4102 T5370 T5371 arg1Of STAT4,","
R4103 T5371 T5369 arg2Of ",",on
R4104 T5371 T5373 arg1Of ",",(
R4105 T5372 T5371 arg2Of signaling,","
R4106 T5375 T5376 arg1Of 2B,and
R4107 T5376 T5373 arg2Of and,(
R4108 T5376 T5374 arg1Of and,Figures
R4109 T5377 T5376 arg2Of 2C,and
R4110 T5378 T5373 arg3Of ),(
R4111 T5380 T5379 arg1Of investigate,To
R4112 T5383 T5382 arg1Of inability,the
R4113 T5383 T5384 arg1Of inability,of
R4114 T5383 T5387 modOf inability,to
R4115 T5383 T5390 arg1Of inability,might
R4116 T5383 T5391 arg1Of inability,be
R4117 T5383 T5393 arg1Of inability,to
R4118 T5386 T5384 arg2Of T cells,of
R4119 T5386 T5385 arg1Of T cells,STAT4-deficient
R4120 T5388 T5387 arg1Of produce,to
R4121 T5389 T5388 arg2Of IL-10,produce
R4122 T5391 T5380 arg2Of be,investigate
R4123 T5391 T5381 arg1Of be,whether
R4124 T5391 T5390 arg2Of be,might
R4125 T5391 T5398 arg1Of be,","
R4126 T5391 T5399 arg1Of be,as
R4127 T5393 T5391 arg2Of to,be
R4128 T5393 T5392 arg1Of to,due
R4129 T5395 T5393 arg2Of absence,to
R4130 T5395 T5394 arg1Of absence,the
R4131 T5395 T5396 arg1Of absence,of
R4132 T5397 T5396 arg2Of IFN-γ,of
R4133 T5400 T5399 arg2Of suggested,as
R4134 T5400 T5401 arg1Of suggested,before
R4135 T5401 T5402 arg1Of before,(
R4136 T5404 T5402 arg2Of et al.,(
R4137 T5404 T5403 arg1Of et al.,Shaw
R4138 T5404 T5405 arg1Of et al.,","
R4139 T5406 T5405 arg2Of 2006,","
R4140 T5407 T5402 arg3Of ),(
R4141 T5409 T5410 arg1Of we,differentiated
R4142 T5410 T5401 arg2Of differentiated,before
R4143 T5410 T5408 arg1Of differentiated,","
R4144 T5410 T5418 arg1Of differentiated,in
R4145 T5415 T5411 arg1Of naive,DO11.10
R4146 T5415 T5412 arg1Of naive,or
R4147 T5415 T5413 arg1Of naive,DO11.10
R4148 T5415 T5414 arg1Of naive,IFN-γ-deficient
R4149 T5417 T5410 arg2Of T cells,differentiated
R4150 T5417 T5415 arg1Of T cells,naive
R4151 T5417 T5416 arg1Of T cells,CD4+
R4152 T5420 T5418 arg2Of presence,in
R4153 T5420 T5419 arg1Of presence,the
R4154 T5420 T5421 arg1Of presence,of
R4155 T5422 T5423 arg1Of IL-12,and
R4156 T5423 T5421 arg2Of and,of
R4157 T5425 T5423 arg2Of doses,and
R4158 T5425 T5424 arg1Of doses,increasing
R4159 T5425 T5426 arg1Of doses,of
R4160 T5427 T5426 arg2Of OVA,of
R4161 T5429 T5430 arg1Of secretion,of
R4162 T5429 T5432 arg1Of secretion,as
R4163 T5429 T5439 arg1Of secretion,and
R4164 T5431 T5430 arg2Of IL-10,of
R4165 T5433 T5432 arg2Of induced,as
R4166 T5437 T5433 arg1Of dose,induced
R4167 T5437 T5434 arg2Of dose,by
R4168 T5437 T5435 arg1Of dose,high
R4169 T5437 T5436 arg1Of dose,antigen
R4170 T5439 T5428 arg1Of and,The
R4171 T5439 T5438 arg1Of and,","
R4172 T5439 T5441 arg1Of and,was
R4173 T5439 T5443 arg2Of and,affected
R4174 T5440 T5439 arg2Of IL-12,and
R4175 T5443 T5441 arg2Of affected,was
R4176 T5443 T5442 arg1Of affected,not
R4177 T5443 T5452 arg1Of affected,","
R4178 T5443 T5453 modOf affected,showing
R4179 T5446 T5443 arg1Of absence,affected
R4180 T5446 T5444 arg2Of absence,by
R4181 T5446 T5445 arg1Of absence,an
R4182 T5446 T5447 arg1Of absence,of
R4183 T5448 T5447 arg2Of IFN-γ,of
R4184 T5448 T5449 arg1Of IFN-γ,(
R4185 T5450 T5449 arg2Of Figure 2D,(
R4186 T5451 T5449 arg3Of ),(
R4187 T5457 T5455 arg1Of of IL-10,the
R4188 T5457 T5456 arg1Of of IL-10,expression
R4189 T5457 T5458 arg1Of of IL-10,by
R4190 T5457 T5461 arg1Of of IL-10,is
R4191 T5457 T5462 arg1Of of IL-10,independent
R4192 T5460 T5458 arg2Of cells,by
R4193 T5460 T5459 arg1Of cells,Th1
R4194 T5461 T5453 arg2Of is,showing
R4195 T5461 T5454 arg1Of is,that
R4196 T5462 T5461 arg2Of independent,is
R4197 T5462 T5463 arg1Of independent,of
R4198 T5464 T5463 arg2Of IFN-γ,of
R4199 T5465 T5466 arg1Of In,the
R4200 T5465 T5468 arg1Of In,of
R4201 T5467 T5465 arg2Of absence,In
R4202 T5469 T5465 arg3Of IFN-γ,In
R4203 T5471 T5472 arg1Of we,observed
R4204 T5472 T5465 arg1Of observed,In
R4205 T5472 T5470 arg1Of observed,","
R4206 T5472 T5479 arg1Of observed,as
R4207 T5474 T5472 arg2Of increase,observed
R4208 T5474 T5473 arg1Of increase,an
R4209 T5474 T5475 arg1Of increase,in
R4210 T5478 T5475 arg2Of IL-4,in
R4211 T5478 T5476 arg1Of IL-4,the
R4212 T5478 T5477 arg2Of IL-4,secreted
R4213 T5480 T5479 arg2Of expected,as
R4214 T5480 T5481 arg1Of expected,(
R4215 T5482 T5481 arg2Of data,(
R4216 T5482 T5484 arg2Of data,shown
R4217 T5484 T5483 arg1Of shown,not
R4218 T5485 T5481 arg3Of ),(
R4219 T5486 T5488 arg1Of We,tested
R4220 T5488 T5487 arg1Of tested,also
R4221 T5488 T5489 arg1Of tested,for
R4222 T5492 T5489 arg2Of role,for
R4223 T5492 T5490 arg1Of role,any
R4224 T5492 T5491 arg1Of role,potential
R4225 T5492 T5493 arg1Of role,of
R4226 T5492 T5495 arg1Of role,in
R4227 T5494 T5493 arg2Of IL-4,of
R4228 T5497 T5495 arg2Of development,in
R4229 T5497 T5496 arg1Of development,the
R4230 T5497 T5498 arg1Of development,of
R4231 T5500 T5498 arg2Of cells,of
R4232 T5500 T5499 arg1Of cells,Th1
R4233 T5500 T5501 arg1Of cells,producing
R4234 T5501 T5503 arg1Of producing,by
R4235 T5502 T5501 arg2Of IL-10,producing
R4236 T5504 T5503 arg2Of culturing,by
R4237 T5505 T5506 arg1Of DO11.10,or
R4238 T5506 T5504 arg2Of or,culturing
R4239 T5511 T5506 arg2Of T cells,or
R4240 T5511 T5507 arg1Of T cells,DO11.10
R4241 T5511 T5508 arg1Of T cells,IL-4-deficient
R4242 T5511 T5509 arg1Of T cells,naive
R4243 T5511 T5510 arg1Of T cells,CD4+
R4244 T5511 T5512 arg1Of T cells,with
R4245 T5513 T5514 arg1Of IL-12,and
R4246 T5514 T5512 arg2Of and,with
R4247 T5516 T5514 arg2Of doses,and
R4248 T5516 T5515 arg1Of doses,increasing
R4249 T5516 T5517 arg1Of doses,of
R4250 T5518 T5517 arg2Of antigen,of
R4251 T5520 T5519 arg2Of observed,As
R4252 T5520 T5521 arg1Of observed,in
R4253 T5523 T5521 arg2Of absence,in
R4254 T5523 T5522 arg1Of absence,the
R4255 T5523 T5524 arg1Of absence,of
R4256 T5525 T5524 arg2Of STAT6,of
R4257 T5525 T5526 arg1Of STAT6,(
R4258 T5527 T5526 arg2Of Figure 2A,(
R4259 T5528 T5526 arg3Of ),(
R4260 T5531 T5530 arg1Of deficiency,IL-4
R4261 T5531 T5532 arg1Of deficiency,had
R4262 T5531 T5548 arg1Of deficiency,compromised
R4263 T5532 T5535 arg1Of had,on
R4264 T5532 T5547 arg1Of had,but
R4265 T5534 T5532 arg2Of effect,had
R4266 T5534 T5533 arg1Of effect,no
R4267 T5537 T5535 arg2Of development,on
R4268 T5537 T5536 arg1Of development,the
R4269 T5537 T5538 arg1Of development,of
R4270 T5540 T5538 arg2Of cells,of
R4271 T5540 T5539 arg1Of cells,Th1
R4272 T5540 T5541 arg1Of cells,producing
R4273 T5542 T5541 arg2Of IL-10,producing
R4274 T5542 T5543 arg1Of IL-10,(
R4275 T5544 T5543 arg2Of Figure 2E,(
R4276 T5545 T5543 arg3Of ),(
R4277 T5547 T5519 arg1Of but,As
R4278 T5547 T5529 arg1Of but,","
R4279 T5547 T5546 arg1Of but,","
R4280 T5548 T5547 arg2Of compromised,but
R4281 T5550 T5548 arg2Of development,compromised
R4282 T5550 T5549 arg1Of development,the
R4283 T5550 T5551 arg1Of development,of
R4284 T5553 T5551 arg2Of cells,of
R4285 T5553 T5552 arg1Of cells,Th2
R4286 T5553 T5554 arg1Of cells,producing
R4287 T5555 T5554 arg2Of IL-10,producing
R4288 T5555 T5556 arg1Of IL-10,(
R4289 T5557 T5556 arg2Of Figure 2F,(
R4290 T5558 T5556 arg3Of ),(
R4291 T5562 T5561 arg1Of data,our
R4292 T5562 T5563 arg1Of data,suggested
R4293 T5563 T5559 arg1Of suggested,Thus
R4294 T5563 T5560 arg1Of suggested,","
R4295 T5566 T5565 arg1Of production,IL-10
R4296 T5566 T5567 arg1Of production,by
R4297 T5566 T5572 arg1Of production,was
R4298 T5566 T5573 arg1Of production,dependent
R4299 T5568 T5569 arg1Of Th1,or
R4300 T5570 T5569 arg2Of Th2,or
R4301 T5571 T5567 arg2Of cells,by
R4302 T5571 T5568 arg1Of cells,Th1
R4303 T5571 T5570 arg1Of cells,Th2
R4304 T5572 T5563 arg2Of was,suggested
R4305 T5572 T5564 arg1Of was,that
R4306 T5572 T5583 arg1Of was,","
R4307 T5572 T5584 arg1Of was,given
R4308 T5573 T5572 arg2Of dependent,was
R4309 T5573 T5574 arg1Of dependent,on
R4310 T5578 T5574 arg2Of pathways,on
R4311 T5578 T5575 arg1Of pathways,the
R4312 T5578 T5576 arg1Of pathways,specific
R4313 T5578 T5577 arg1Of pathways,signaling
R4314 T5578 T5579 arg2Of pathways,required
R4315 T5579 T5580 arg1Of required,for
R4316 T5582 T5580 arg2Of differentiation,for
R4317 T5582 T5581 arg1Of differentiation,their
R4318 T5586 T5587 arg1Of STAT4,is
R4319 T5586 T5588 arg2Of STAT4,required
R4320 T5588 T5584 arg2Of required,given
R4321 T5588 T5585 arg1Of required,that
R4322 T5588 T5587 arg2Of required,is
R4323 T5588 T5589 arg1Of required,for
R4324 T5591 T5589 arg2Of induction,for
R4325 T5591 T5590 arg1Of induction,the
R4326 T5591 T5592 arg1Of induction,of
R4327 T5594 T5593 arg1Of production,IL-10
R4328 T5594 T5595 arg1Of production,by
R4329 T5594 T5598 arg1Of production,and
R4330 T5597 T5595 arg2Of cells,by
R4331 T5597 T5596 arg1Of cells,Th1
R4332 T5598 T5592 arg2Of and,of
R4333 T5599 T5598 arg2Of STAT6,and
R4334 T5599 T5600 arg1Of STAT6,for
R4335 T5602 T5600 arg2Of cells,for
R4336 T5602 T5601 arg1Of cells,Th2
R5322 T7044 T7042 arg1Of Doses,High
R5323 T7044 T7043 arg1Of Doses,Antigen
R5324 T7044 T7045 arg1Of Doses,and
R5325 T7045 T7047 arg1Of and,Are
R5326 T7045 T7048 arg2Of and,Required
R5327 T7046 T7045 arg2Of STAT4,and
R5328 T7048 T7047 arg2Of Required,Are
R5329 T7048 T7049 arg1Of Required,for
R5330 T7053 T7049 arg2Of Generation,for
R5331 T7053 T7050 arg1Of Generation,the
R5332 T7053 T7051 arg1Of Generation,In
R5333 T7053 T7052 arg1Of Generation,Vivo
R5334 T7053 T7054 arg1Of Generation,of
R5335 T7057 T7054 arg2Of Cells,of
R5336 T7057 T7055 arg1Of Cells,IL-10-Producing
R5337 T7057 T7056 arg1Of Cells,Th1
R5338 T7059 T7058 arg1Of address,To
R5339 T7061 T7059 arg2Of mechanisms,address
R5340 T7061 T7060 arg1Of mechanisms,the
R5341 T7061 T7062 arg1Of mechanisms,regulating
R5342 T7064 T7062 arg2Of production,regulating
R5343 T7064 T7063 arg1Of production,IL-10
R5344 T7064 T7065 arg1Of production,by
R5345 T7067 T7065 arg2Of cells,by
R5346 T7067 T7066 arg1Of cells,Th1
R5347 T7067 T7068 arg1Of cells,in vivo
R5348 T7070 T7059 arg1Of we,address
R5349 T7070 T7071 arg1Of we,transferred
R5350 T7070 T7079 arg1Of we,immunized
R5351 T7071 T7074 arg1Of transferred,into
R5352 T7071 T7078 arg1Of transferred,and
R5353 T7073 T7071 arg2Of cells,transferred
R5354 T7073 T7072 arg1Of cells,DO11.10
R5355 T7077 T7074 arg2Of mice,into
R5356 T7077 T7075 arg1Of mice,BALB/c
R5357 T7077 T7076 arg1Of mice,recipient
R5358 T7078 T7058 modOf and,To
R5359 T7078 T7069 arg1Of and,","
R5360 T7079 T7078 arg2Of immunized,and
R5361 T7079 T7082 arg1Of immunized,with
R5362 T7079 T7088 arg1Of immunized,with
R5363 T7079 T7090 arg1Of immunized,without
R5364 T7081 T7079 arg2Of recipients,immunized
R5365 T7081 T7080 arg1Of recipients,the
R5366 T7084 T7083 arg1Of high,very
R5367 T7085 T7082 arg2Of doses,with
R5368 T7085 T7084 arg1Of doses,high
R5369 T7085 T7086 arg1Of doses,of
R5370 T7087 T7086 arg2Of OVA-protein,of
R5371 T7088 T7089 arg1Of with,or
R5372 T7090 T7089 arg2Of without,or
R5373 T7092 T7088 arg2Of lipopolysacharide,with
R5374 T7092 T7090 arg2Of lipopolysacharide,without
R5375 T7092 T7091 arg2Of lipopolysacharide,added
R5376 T7092 T7093 arg1Of lipopolysacharide,(
R5377 T7094 T7093 arg2Of LPS,(
R5378 T7095 T7093 arg3Of ),(
R5379 T7096 T7097 arg1Of T cells,were
R5380 T7096 T7098 arg2Of T cells,recovered
R5381 T7096 T7109 arg1Of T cells,restimulated
R5382 T7098 T7097 arg2Of recovered,were
R5383 T7098 T7099 arg1Of recovered,from
R5384 T7098 T7106 arg1Of recovered,after
R5385 T7098 T7108 arg1Of recovered,and
R5386 T7103 T7099 arg2Of nodes,from
R5387 T7103 T7100 arg1Of nodes,the
R5388 T7103 T7101 arg1Of nodes,inguinal
R5389 T7103 T7102 arg1Of nodes,lymph
R5390 T7105 T7104 arg1Of days,3
R5391 T7106 T7105 arg1Of after,days
R5392 T7107 T7106 arg2Of priming,after
R5393 T7109 T7108 arg2Of restimulated,and
R5394 T7109 T7111 arg1Of restimulated,with
R5395 T7110 T7109 arg2Of in vitro,restimulated
R5396 T7113 T7111 arg2Of peptide,with
R5397 T7113 T7112 arg1Of peptide,OVA
R5398 T7113 T7114 arg1Of peptide,for
R5399 T7116 T7114 arg2Of hr,for
R5400 T7116 T7115 arg1Of hr,48
R5401 T7119 T7117 arg1Of immunization,This
R5402 T7119 T7118 arg1Of immunization,in vivo
R5403 T7119 T7120 arg1Of immunization,induced
R5404 T7120 T7126 arg1Of induced,and
R5405 T7121 T7122 arg1Of IL-10,and
R5406 T7123 T7122 arg2Of IFN-γ,and
R5407 T7124 T7120 arg2Of production,induced
R5408 T7124 T7121 arg1Of production,IL-10
R5409 T7124 T7123 arg1Of production,IFN-γ
R5410 T7126 T7125 arg1Of and,","
R5411 T7128 T7127 arg1Of amount,the
R5412 T7128 T7129 arg1Of amount,of
R5413 T7128 T7132 arg1Of amount,was
R5414 T7128 T7133 arg2Of amount,enhanced
R5415 T7131 T7129 arg2Of production,of
R5416 T7131 T7130 arg1Of production,IL-10
R5417 T7133 T7126 arg2Of enhanced,and
R5418 T7133 T7132 arg2Of enhanced,was
R5419 T7135 T7133 arg1Of addition,enhanced
R5420 T7135 T7134 arg2Of addition,by
R5421 T7135 T7136 arg1Of addition,of
R5422 T7135 T7138 arg1Of addition,in
R5423 T7135 T7145 arg1Of addition,with
R5424 T7137 T7136 arg2Of LPS,of
R5425 T7138 T7144 arg1Of in,and
R5426 T7140 T7138 arg2Of immunization,in
R5427 T7140 T7139 arg1Of immunization,the
R5428 T7140 T7141 arg1Of immunization,(
R5429 T7142 T7141 arg2Of Figure 3A,(
R5430 T7143 T7141 arg3Of ),(
R5431 T7145 T7144 arg2Of with,and
R5432 T7147 T7145 arg2Of doses,with
R5433 T7147 T7146 arg1Of doses,higher
R5434 T7147 T7148 arg1Of doses,of
R5435 T7147 T7150 arg1Of doses,(
R5436 T7149 T7148 arg2Of OVA,of
R5437 T7152 T7150 arg2Of μM,(
R5438 T7152 T7151 arg1Of μM,3
R5439 T7152 T7153 arg1Of μM,versus
R5440 T7155 T7153 arg2Of μM,versus
R5441 T7155 T7154 arg1Of μM,1
R5442 T7155 T7156 arg1Of μM,","
R5443 T7157 T7156 arg2Of data,","
R5444 T7157 T7159 arg2Of data,shown
R5445 T7159 T7158 arg1Of shown,not
R5446 T7160 T7150 arg3Of ),(
R5447 T7162 T7161 arg1Of test,To
R5448 T7164 T7162 arg2Of role,test
R5449 T7164 T7163 arg1Of role,the
R5450 T7164 T7165 arg1Of role,of
R5451 T7164 T7170 arg1Of role,in
R5452 T7166 T7167 arg1Of STAT4,and
R5453 T7168 T7167 arg2Of STAT6,and
R5454 T7169 T7165 arg2Of signaling,of
R5455 T7169 T7166 arg1Of signaling,STAT4
R5456 T7169 T7168 arg1Of signaling,STAT6
R5457 T7173 T7170 arg2Of development,in
R5458 T7173 T7171 arg1Of development,the
R5459 T7173 T7172 arg1Of development,in vivo
R5460 T7173 T7174 arg1Of development,of
R5461 T7177 T7174 arg2Of cells,of
R5462 T7177 T7175 arg1Of cells,IL-10-producing
R5463 T7177 T7176 arg1Of cells,Th1
R5464 T7179 T7162 arg1Of we,test
R5465 T7179 T7180 arg1Of we,transferred
R5466 T7180 T7161 modOf transferred,To
R5467 T7180 T7178 arg1Of transferred,","
R5468 T7181 T7182 arg1Of STAT4-,or
R5469 T7182 T7180 arg2Of or,transferred
R5470 T7183 T7184 arg1Of STAT6-deficient,or
R5471 T7185 T7184 arg2Of WT,or
R5472 T7187 T7182 arg2Of cells,or
R5473 T7187 T7183 arg1Of cells,STAT6-deficient
R5474 T7187 T7185 arg1Of cells,WT
R5475 T7187 T7186 arg1Of cells,DO11.10
R5476 T7187 T7188 arg1Of cells,into
R5477 T7187 T7193 arg2Of cells,immunized
R5478 T7188 T7192 arg1Of into,and
R5479 T7191 T7188 arg2Of mice,into
R5480 T7191 T7189 arg1Of mice,recipient
R5481 T7191 T7190 arg1Of mice,BALB/c
R5482 T7193 T7192 arg2Of immunized,and
R5483 T7193 T7194 arg1Of immunized,with
R5484 T7194 T7199 arg1Of with,before
R5485 T7195 T7196 arg1Of OVA-protein,plus
R5486 T7196 T7194 arg2Of plus,with
R5487 T7197 T7196 arg2Of LPS,plus
R5488 T7199 T7198 arg1Of before,as
R5489 T7201 T7200 arg1Of vivo,In
R5490 T7202 T7201 arg1Of expression,vivo
R5491 T7202 T7203 arg1Of expression,of
R5492 T7202 T7208 arg1Of expression,was
R5493 T7202 T7210 arg2Of expression,reduced
R5494 T7202 T7214 arg2Of expression,abrogated
R5495 T7205 T7206 arg1Of IL-10,and
R5496 T7206 T7203 arg2Of and,of
R5497 T7206 T7204 arg1Of and,both
R5498 T7207 T7206 arg2Of IFN-γ,and
R5499 T7210 T7211 arg1Of reduced,but
R5500 T7211 T7208 arg2Of but,was
R5501 T7211 T7209 arg1Of but,markedly
R5502 T7213 T7212 arg1Of completely,not
R5503 T7214 T7211 arg2Of abrogated,but
R5504 T7214 T7213 arg1Of abrogated,completely
R5505 T7214 T7215 arg1Of abrogated,in
R5506 T7214 T7227 arg1Of abrogated,","
R5507 T7214 T7228 modOf abrogated,suggesting
R5508 T7217 T7215 arg2Of absence,in
R5509 T7217 T7216 arg1Of absence,the
R5510 T7217 T7218 arg1Of absence,of
R5511 T7220 T7218 arg2Of signaling,of
R5512 T7220 T7219 arg1Of signaling,STAT4
R5513 T7220 T7221 arg1Of signaling,(
R5514 T7223 T7224 arg1Of 3B,and
R5515 T7224 T7221 arg2Of and,(
R5516 T7224 T7222 arg1Of and,Figures
R5517 T7225 T7224 arg2Of 3C,and
R5518 T7226 T7221 arg3Of ),(
R5519 T7230 T7228 arg2Of existence,suggesting
R5520 T7230 T7229 arg1Of existence,the
R5521 T7230 T7231 arg1Of existence,of
R5522 T7233 T7231 arg2Of mechanisms,of
R5523 T7233 T7232 arg1Of mechanisms,compensatory
R5524 T7233 T7234 arg1Of mechanisms,that
R5525 T7233 T7235 arg1Of mechanisms,were
R5526 T7233 T7236 arg1Of mechanisms,absent
R5527 T7236 T7235 arg2Of absent,were
R5528 T7236 T7237 arg1Of absent,in
R5529 T7240 T7237 arg2Of system,in
R5530 T7240 T7238 arg1Of system,the
R5531 T7240 T7239 arg1Of system,in vitro
R5532 T7241 T7242 arg1Of Signaling,through
R5533 T7241 T7244 arg1Of Signaling,had
R5534 T7243 T7242 arg2Of STAT6,through
R5535 T7244 T7247 arg1Of had,on
R5536 T7244 T7263 arg1Of had,by
R5537 T7246 T7244 arg2Of effect,had
R5538 T7246 T7245 arg1Of effect,no
R5539 T7247 T7262 arg1Of on,and
R5540 T7249 T7247 arg2Of production,on
R5541 T7249 T7248 arg1Of production,IL-10
R5542 T7249 T7250 arg1Of production,by
R5543 T7249 T7253 arg1Of production,as
R5544 T7252 T7250 arg2Of cells,by
R5545 T7252 T7251 arg1Of cells,Th1
R5546 T7254 T7253 arg2Of shown,as
R5547 T7258 T7254 arg1Of staining,shown
R5548 T7258 T7255 arg2Of staining,by
R5549 T7258 T7256 arg1Of staining,intracellular
R5550 T7258 T7257 arg1Of staining,cytokine
R5551 T7258 T7259 arg1Of staining,(
R5552 T7260 T7259 arg2Of ICS,(
R5553 T7261 T7259 arg3Of ),(
R5554 T7263 T7262 arg2Of by,and
R5555 T7264 T7263 arg2Of immunoassay,by
R5556 T7264 T7265 arg1Of immunoassay,in
R5557 T7267 T7265 arg2Of T cells,in
R5558 T7267 T7266 arg1Of T cells,STAT6-deficient
R5559 T7267 T7268 arg1Of T cells,(
R5560 T7270 T7271 arg1Of 3B,and
R5561 T7271 T7268 arg2Of and,(
R5562 T7271 T7269 arg1Of and,Figures
R5563 T7272 T7271 arg2Of 3C,and
R5564 T7273 T7268 arg3Of ),(
R6009 T7939 T7938 arg1Of Production,IL-10
R6010 T7939 T7940 arg1Of Production,Is
R6011 T7939 T7941 arg2Of Production,Maintained
R6012 T7941 T7940 arg2Of Maintained,Is
R6013 T7946 T7947 arg1Of Strength,and
R6014 T7947 T7941 arg1Of and,Maintained
R6015 T7947 T7942 arg2Of and,by
R6016 T7947 T7943 arg1Of and,High
R6017 T7947 T7944 arg1Of and,TCR
R6018 T7947 T7945 arg1Of and,Signal
R6019 T7948 T7947 arg2Of IL-12,and
R6020 T7949 T7951 arg1Of We,investigated
R6021 T7951 T7950 arg1Of investigated,next
R6022 T7956 T7953 arg2Of activation,repeated
R6023 T7956 T7954 arg1Of activation,strong
R6024 T7956 T7955 arg1Of activation,TCR
R6025 T7956 T7957 arg1Of activation,is
R6026 T7957 T7951 arg2Of is,investigated
R6027 T7957 T7952 arg1Of is,whether
R6028 T7960 T7957 arg2Of signal,is
R6029 T7960 T7958 arg1Of signal,a
R6030 T7960 T7959 arg1Of signal,compensatory
R6031 T7960 T7961 arg1Of signal,for
R6032 T7964 T7961 arg2Of signaling,for
R6033 T7964 T7962 arg1Of signaling,IL-12-induced
R6034 T7964 T7963 arg1Of signaling,STAT4
R6035 T7964 T7965 arg1Of signaling,in
R6036 T7967 T7965 arg2Of induction,in
R6037 T7967 T7966 arg1Of induction,the
R6038 T7967 T7968 arg1Of induction,of
R6039 T7967 T7970 arg1Of induction,in
R6040 T7969 T7968 arg2Of IL-10,of
R6041 T7972 T7970 arg2Of cells,in
R6042 T7972 T7971 arg1Of cells,Th1
R6043 T7974 T7973 arg2Of this,For
R6044 T7977 T7976 arg1Of T cells,CD4+
R6045 T7977 T7978 arg1Of T cells,were
R6046 T7977 T7979 arg2Of T cells,differentiated
R6047 T7979 T7973 arg1Of differentiated,For
R6048 T7979 T7975 arg1Of differentiated,","
R6049 T7979 T7978 arg2Of differentiated,were
R6050 T7979 T7980 arg1Of differentiated,for
R6051 T7979 T7984 arg1Of differentiated,with
R6052 T7979 T7988 arg1Of differentiated,in
R6053 T7983 T7980 arg2Of weeks,for
R6054 T7983 T7981 arg1Of weeks,2
R6055 T7983 T7982 arg1Of weeks,consecutive
R6056 T7987 T7984 arg2Of doses,with
R6057 T7987 T7985 arg1Of doses,high
R6058 T7987 T7986 arg1Of doses,antigen
R6059 T7990 T7991 arg1Of presence,or
R6060 T7991 T7988 arg2Of or,in
R6061 T7991 T7989 arg1Of or,the
R6062 T7991 T7993 arg1Of or,of
R6063 T7991 T7995 arg1Of or,throughout
R6064 T7992 T7991 arg2Of absence,or
R6065 T7994 T7993 arg2Of IL-12,of
R6066 T7995 T7996 arg1Of throughout,(
R6067 T7998 T7996 arg2Of 4A–4D,(
R6068 T7998 T7997 arg1Of 4A–4D,Figures
R6069 T7999 T7996 arg3Of ),(
R6070 T8002 T8003 arg1Of dose,and
R6071 T8003 T8000 arg1Of and,High
R6072 T8003 T8001 arg1Of and,antigen
R6073 T8003 T8005 arg1Of and,cooperated
R6074 T8004 T8003 arg2Of IL-12,and
R6075 T8005 T8017 arg1Of cooperated,","
R6076 T8005 T8018 arg1Of cooperated,given
R6077 T8007 T8005 arg2Of induce,cooperated
R6078 T8007 T8006 arg1Of induce,to
R6079 T8010 T8007 arg2Of production,induce
R6080 T8010 T8008 arg1Of production,maximal
R6081 T8010 T8009 arg1Of production,IL-10
R6082 T8010 T8011 arg1Of production,(
R6083 T8013 T8014 arg1Of 4A,and
R6084 T8014 T8011 arg2Of and,(
R6085 T8014 T8012 arg1Of and,Figures
R6086 T8015 T8014 arg2Of 4B,and
R6087 T8016 T8011 arg3Of ),(
R6088 T8021 T8020 arg1Of combination,this
R6089 T8021 T8022 arg1Of combination,resulted
R6090 T8022 T8018 arg2Of resulted,given
R6091 T8022 T8019 arg1Of resulted,that
R6092 T8022 T8023 arg1Of resulted,in
R6093 T8026 T8023 arg2Of numbers,in
R6094 T8026 T8024 arg1Of numbers,the
R6095 T8026 T8025 arg1Of numbers,highest
R6096 T8026 T8027 arg1Of numbers,of
R6097 T8030 T8027 arg2Of cells,of
R6098 T8030 T8028 arg1Of cells,IL-10-producing
R6099 T8030 T8029 arg1Of cells,Th1
R6100 T8035 T8031 arg2Of stimulation,Repeated
R6101 T8035 T8032 arg1Of stimulation,high
R6102 T8035 T8033 arg1Of stimulation,antigen
R6103 T8035 T8034 arg1Of stimulation,dose
R6104 T8035 T8036 arg1Of stimulation,in
R6105 T8035 T8043 arg1Of stimulation,resulted
R6106 T8038 T8036 arg2Of absence,in
R6107 T8038 T8037 arg1Of absence,the
R6108 T8038 T8039 arg1Of absence,of
R6109 T8041 T8040 arg1Of added,exogenously
R6110 T8042 T8039 arg2Of IL-12,of
R6111 T8042 T8041 arg1Of IL-12,added
R6112 T8043 T8044 arg1Of resulted,in
R6113 T8043 T8052 arg1Of resulted,","
R6114 T8043 T8053 modOf resulted,suggesting
R6115 T8046 T8044 arg2Of production,in
R6116 T8046 T8045 arg1Of production,the
R6117 T8046 T8047 arg1Of production,of
R6118 T8046 T8049 arg1Of production,by
R6119 T8048 T8047 arg2Of IL-10,of
R6120 T8051 T8049 arg2Of cells,by
R6121 T8051 T8050 arg1Of cells,Th1
R6122 T8058 T8055 arg2Of triggering,repeated
R6123 T8058 T8056 arg1Of triggering,strong
R6124 T8058 T8057 arg1Of triggering,TCR
R6125 T8058 T8059 arg1Of triggering,may
R6126 T8058 T8060 arg1Of triggering,overcome
R6127 T8060 T8053 arg2Of overcome,suggesting
R6128 T8060 T8054 arg1Of overcome,that
R6129 T8060 T8059 arg2Of overcome,may
R6130 T8062 T8060 arg2Of need,overcome
R6131 T8062 T8061 arg1Of need,the
R6132 T8062 T8063 arg1Of need,for
R6133 T8064 T8063 arg2Of IL-12,for
R6134 T8064 T8065 arg1Of IL-12,for
R6135 T8067 T8065 arg2Of induction,for
R6136 T8067 T8066 arg1Of induction,IL-10
R6137 T8067 T8068 arg1Of induction,(
R6138 T8070 T8071 arg1Of 4C,and
R6139 T8071 T8068 arg2Of and,(
R6140 T8071 T8069 arg1Of and,Figures
R6141 T8072 T8071 arg2Of 4D,and
R6142 T8073 T8068 arg3Of ),(
R6143 T8077 T8076 arg1Of induction,IL-10
R6144 T8077 T8078 arg1Of induction,under
R6145 T8077 T8081 arg1Of induction,was
R6146 T8077 T8082 arg2Of induction,abrogated
R6147 T8080 T8078 arg2Of conditions,under
R6148 T8080 T8079 arg1Of conditions,these
R6149 T8082 T8074 arg1Of abrogated,However
R6150 T8082 T8075 arg1Of abrogated,","
R6151 T8082 T8081 arg2Of abrogated,was
R6152 T8082 T8083 arg1Of abrogated,when
R6153 T8085 T8084 arg1Of DCs,IL-12p40-deficient
R6154 T8085 T8086 arg1Of DCs,were
R6155 T8085 T8087 arg2Of DCs,used
R6156 T8087 T8083 arg2Of used,when
R6157 T8087 T8086 arg2Of used,were
R6158 T8087 T8088 arg1Of used,as
R6159 T8089 T8088 arg2Of APCs,as
R6160 T8089 T8090 arg1Of APCs,(
R6161 T8091 T8090 arg2Of Figure 4E,(
R6162 T8092 T8090 arg3Of ),(
R6163 T8095 T8096 arg1Of IL-12,is
R6164 T8095 T8097 arg1Of IL-12,essential
R6165 T8096 T8093 arg1Of is,Thus
R6166 T8096 T8094 arg1Of is,","
R6167 T8097 T8096 arg2Of essential,is
R6168 T8097 T8098 arg1Of essential,during
R6169 T8100 T8101 arg1Of primary,and
R6170 T8101 T8099 arg1Of and,both
R6171 T8102 T8101 arg2Of secondary,and
R6172 T8104 T8098 arg2Of stimulation,during
R6173 T8104 T8100 arg1Of stimulation,primary
R6174 T8104 T8102 arg1Of stimulation,secondary
R6175 T8104 T8103 arg1Of stimulation,antigenic
R6176 T8104 T8105 arg1Of stimulation,for
R6177 T8106 T8105 arg2Of production,for
R6178 T8106 T8107 arg1Of production,of
R6179 T8106 T8109 arg1Of production,by
R6180 T8108 T8107 arg2Of IL-10,of
R6181 T8111 T8109 arg2Of cells,by
R6182 T8111 T8110 arg1Of cells,Th1
R6183 T8113 T8112 arg1Of determine,To
R6184 T8115 T8113 arg2Of requirements,determine
R6185 T8115 T8114 arg1Of requirements,the
R6186 T8115 T8116 arg1Of requirements,for
R6187 T8117 T8116 arg2Of stability,for
R6188 T8117 T8118 arg1Of stability,of
R6189 T8122 T8118 arg2Of cells,of
R6190 T8122 T8119 arg1Of cells,the
R6191 T8122 T8120 arg1Of cells,IL-10-producing
R6192 T8122 T8121 arg1Of cells,Th1
R6193 T8124 T8113 arg1Of we,determine
R6194 T8124 T8125 arg1Of we,differentiated
R6195 T8124 T8146 arg1Of we,washed
R6196 T8124 T8151 arg1Of we,restimulated
R6197 T8125 T8128 arg1Of differentiated,for
R6198 T8125 T8131 arg1Of differentiated,with
R6199 T8125 T8145 arg1Of differentiated,","
R6200 T8127 T8125 arg2Of T cells,differentiated
R6201 T8127 T8126 arg1Of T cells,CD4+
R6202 T8130 T8128 arg2Of week,for
R6203 T8130 T8129 arg1Of week,1
R6204 T8134 T8131 arg2Of doses,with
R6205 T8134 T8132 arg1Of doses,high
R6206 T8134 T8133 arg1Of doses,antigen
R6207 T8134 T8135 arg1Of doses,with
R6208 T8134 T8137 arg1Of doses,without
R6209 T8135 T8136 arg1Of with,or
R6210 T8137 T8136 arg2Of without,or
R6211 T8138 T8135 arg2Of IL-12,with
R6212 T8138 T8137 arg2Of IL-12,without
R6213 T8138 T8139 arg1Of IL-12,(
R6214 T8141 T8142 arg1Of 4A,and
R6215 T8142 T8139 arg2Of and,(
R6216 T8142 T8140 arg1Of and,Figures
R6217 T8143 T8142 arg2Of 4C,and
R6218 T8144 T8139 arg3Of ),(
R6219 T8145 T8149 arg1Of ",",and
R6220 T8146 T8145 arg2Of washed,","
R6221 T8147 T8146 arg2Of them,washed
R6222 T8149 T8112 modOf and,To
R6223 T8149 T8123 arg1Of and,","
R6224 T8149 T8148 arg1Of and,","
R6225 T8151 T8149 arg2Of restimulated,and
R6226 T8151 T8150 arg1Of restimulated,then
R6227 T8151 T8153 arg1Of restimulated,for
R6228 T8151 T8157 arg1Of restimulated,with
R6229 T8151 T8162 arg1Of restimulated,","
R6230 T8151 T8163 arg1Of restimulated,in
R6231 T8152 T8151 arg2Of them,restimulated
R6232 T8156 T8153 arg2Of week,for
R6233 T8156 T8154 arg1Of week,an
R6234 T8156 T8155 arg1Of week,additional
R6235 T8161 T8157 arg2Of dose,with
R6236 T8161 T8158 arg1Of dose,a
R6237 T8161 T8159 arg1Of dose,low
R6238 T8161 T8160 arg1Of dose,antigen
R6239 T8165 T8166 arg1Of absence,or
R6240 T8166 T8163 arg2Of or,in
R6241 T8166 T8164 arg1Of or,the
R6242 T8166 T8168 arg1Of or,of
R6243 T8167 T8166 arg2Of presence,or
R6244 T8169 T8168 arg2Of IL-12,of
R6245 T8169 T8170 arg1Of IL-12,(
R6246 T8171 T8170 arg2Of Figure 4F,(
R6247 T8172 T8170 arg3Of ),(
R6248 T8174 T8173 arg1Of cells,Th1
R6249 T8174 T8175 arg2Of cells,induced
R6250 T8174 T8191 arg1Of cells,lost
R6251 T8175 T8176 arg1Of induced,in
R6252 T8175 T8180 modOf induced,to
R6253 T8179 T8176 arg2Of week,in
R6254 T8179 T8177 arg1Of week,the
R6255 T8179 T8178 arg1Of week,first
R6256 T8181 T8180 arg1Of produce,to
R6257 T8181 T8183 arg1Of produce,by
R6258 T8182 T8181 arg2Of IL-10,produce
R6259 T8184 T8183 arg2Of culture,by
R6260 T8184 T8185 arg1Of culture,with
R6261 T8188 T8186 arg1Of doses,high
R6262 T8188 T8187 arg1Of doses,antigen
R6263 T8188 T8189 arg1Of doses,and
R6264 T8189 T8185 arg2Of and,with
R6265 T8190 T8189 arg2Of IL-12,and
R6266 T8193 T8191 arg2Of ability,lost
R6267 T8193 T8192 arg1Of ability,their
R6268 T8193 T8194 modOf ability,to
R6269 T8193 T8204 arg1Of ability,","
R6270 T8193 T8205 arg1Of ability,which
R6271 T8193 T8206 arg1Of ability,could
R6272 T8193 T8207 arg1Of ability,be
R6273 T8193 T8208 arg2Of ability,compensated
R6274 T8195 T8194 arg1Of express,to
R6275 T8195 T8197 arg1Of express,when
R6276 T8196 T8195 arg2Of IL-10,express
R6277 T8198 T8197 arg2Of recultured,when
R6278 T8198 T8199 arg1Of recultured,with
R6279 T8201 T8199 arg2Of doses,with
R6280 T8201 T8200 arg1Of doses,low
R6281 T8201 T8202 arg1Of doses,of
R6282 T8203 T8202 arg2Of OVA,of
R6283 T8208 T8206 arg2Of compensated,could
R6284 T8208 T8207 arg2Of compensated,be
R6285 T8208 T8209 arg1Of compensated,for
R6286 T8208 T8211 arg1Of compensated,to
R6287 T8208 T8214 arg1Of compensated,","
R6288 T8208 T8215 arg1Of compensated,by
R6289 T8208 T8226 arg1Of compensated,","
R6290 T8208 T8228 modOf compensated,suggesting
R6291 T8209 T8210 arg1Of for,","
R6292 T8211 T8210 arg2Of to,","
R6293 T8213 T8211 arg2Of extent,to
R6294 T8213 T8212 arg1Of extent,some
R6295 T8216 T8215 arg2Of addition,by
R6296 T8216 T8217 arg1Of addition,of
R6297 T8216 T8219 arg1Of addition,to
R6298 T8218 T8217 arg2Of IL-12,of
R6299 T8222 T8219 arg2Of cultures,to
R6300 T8222 T8220 arg1Of cultures,the
R6301 T8222 T8221 arg1Of cultures,secondary
R6302 T8222 T8223 arg1Of cultures,(
R6303 T8224 T8223 arg2Of Figure 4F,(
R6304 T8225 T8223 arg3Of ),(
R6305 T8228 T8227 arg1Of suggesting,again
R6306 T8231 T8232 arg1Of dose,and
R6307 T8233 T8232 arg2Of IL-12,and
R6308 T8234 T8230 arg1Of signals,antigen
R6309 T8234 T8231 arg1Of signals,dose
R6310 T8234 T8233 arg1Of signals,IL-12
R6311 T8234 T8235 arg1Of signals,cooperate
R6312 T8235 T8228 arg2Of cooperate,suggesting
R6313 T8235 T8229 arg1Of cooperate,that
R6314 T8235 T8236 arg1Of cooperate,for
R6315 T8238 T8236 arg2Of induction,for
R6316 T8238 T8237 arg1Of induction,the
R6317 T8238 T8239 arg1Of induction,of
R6318 T8240 T8239 arg2Of IL-10,of
R6319 T8245 T8243 arg1Of cells,DO11.10
R6320 T8245 T8244 arg1Of cells,CD4+
R6321 T8245 T8246 arg1Of cells,that
R6322 T8245 T8247 arg1Of cells,were
R6323 T8245 T8248 arg2Of cells,exposed
R6324 T8245 T8261 arg1Of cells,produced
R6325 T8248 T8247 arg2Of exposed,were
R6326 T8248 T8249 arg1Of exposed,to
R6327 T8248 T8256 arg1Of exposed,during
R6328 T8251 T8249 arg2Of doses,to
R6329 T8251 T8250 arg1Of doses,low
R6330 T8251 T8252 arg1Of doses,of
R6331 T8253 T8254 arg1Of antigen,and
R6332 T8254 T8252 arg2Of and,of
R6333 T8255 T8254 arg2Of IL-12,and
R6334 T8260 T8256 arg2Of phase,during
R6335 T8260 T8257 arg1Of phase,the
R6336 T8260 T8258 arg1Of phase,primary
R6337 T8260 T8259 arg1Of phase,differentiation
R6338 T8261 T8270 arg1Of produced,but
R6339 T8263 T8261 arg2Of amounts,produced
R6340 T8263 T8262 arg1Of amounts,high
R6341 T8263 T8264 arg1Of amounts,of
R6342 T8265 T8266 arg1Of IFN-γ,but
R6343 T8267 T8266 arg2Of little,but
R6344 T8268 T8264 arg2Of IL-10,of
R6345 T8268 T8265 arg1Of IL-10,IFN-γ
R6346 T8268 T8267 arg1Of IL-10,little
R6347 T8270 T8241 arg1Of but,Finally
R6348 T8270 T8242 arg1Of but,","
R6349 T8270 T8269 arg1Of but,","
R6350 T8271 T8272 arg1Of they,could
R6351 T8271 T8273 arg1Of they,be
R6352 T8271 T8274 arg2Of they,induced
R6353 T8271 T8276 arg1Of they,produce
R6354 T8274 T8270 arg2Of induced,but
R6355 T8274 T8272 arg2Of induced,could
R6356 T8274 T8273 arg2Of induced,be
R6357 T8276 T8274 arg3Of produce,induced
R6358 T8276 T8275 arg1Of produce,to
R6359 T8276 T8278 arg1Of produce,when
R6360 T8277 T8276 arg2Of IL-10,produce
R6361 T8282 T8280 arg1Of dose,high
R6362 T8282 T8281 arg1Of dose,antigen
R6363 T8282 T8283 arg1Of dose,and
R6364 T8283 T8279 arg1Of and,both
R6365 T8283 T8285 arg1Of and,were
R6366 T8283 T8286 arg1Of and,present
R6367 T8284 T8283 arg2Of IL-12,and
R6368 T8285 T8278 arg2Of were,when
R6369 T8286 T8285 arg2Of present,were
R6370 T8286 T8287 arg1Of present,during
R6371 T8290 T8287 arg2Of phase,during
R6372 T8290 T8288 arg1Of phase,the
R6373 T8290 T8289 arg1Of phase,recall
R6374 T8290 T8291 arg1Of phase,(
R6375 T8292 T8291 arg2Of Figure S4,(
R6376 T8293 T8291 arg3Of ),(
R6377 T8298 T8299 arg1Of dose,and
R6378 T8299 T8296 arg1Of and,high
R6379 T8299 T8297 arg1Of and,antigen
R6380 T8299 T8301 arg1Of and,are
R6381 T8299 T8302 arg2Of and,required
R6382 T8300 T8299 arg2Of IL-12,and
R6383 T8302 T8294 arg1Of required,Thus
R6384 T8302 T8295 arg1Of required,","
R6385 T8302 T8301 arg2Of required,are
R6386 T8302 T8303 arg1Of required,for
R6387 T8304 T8303 arg2Of sustaining,for
R6388 T8306 T8304 arg2Of induction,sustaining
R6389 T8306 T8305 arg1Of induction,the
R6390 T8306 T8307 arg1Of induction,of
R6391 T8306 T8310 arg1Of induction,by
R6392 T8309 T8307 arg2Of production,of
R6393 T8309 T8308 arg1Of production,IL-10
R6394 T8312 T8310 arg2Of cells,by
R6395 T8312 T8311 arg1Of cells,Th1
R66 T155 T154 arg1Of Production,Interleukin-10
R67 T155 T156 arg1Of Production,by
R68 T155 T159 arg1Of Production,Requires
R69 T158 T156 arg2Of Cells,by
R70 T158 T157 arg1Of Cells,Th1
R71 T163 T160 arg1Of Factor,Interleukin-12-Induced
R7166 T9393 T9392 arg1Of Production,IL-10
R7167 T9393 T9394 arg1Of Production,by
R7168 T9393 T9397 arg1Of Production,Requires
R7169 T9396 T9394 arg2Of Cells,by
R7170 T9396 T9395 arg1Of Cells,Th1
R7171 T9398 T9399 arg1Of ERK1,and
R7172 T9400 T9399 arg2Of ERK2,and
R7173 T9401 T9397 arg2Of Activation,Requires
R7174 T9401 T9398 arg1Of Activation,ERK1
R7175 T9401 T9400 arg1Of Activation,ERK2
R7176 T9403 T9402 arg1Of data,Our
R7177 T9403 T9404 arg1Of data,showed
R7178 T9407 T9406 arg1Of maintenance,the
R7179 T9407 T9408 arg1Of maintenance,of
R7180 T9407 T9411 arg1Of maintenance,in
R7181 T9407 T9414 arg1Of maintenance,required
R7182 T9410 T9408 arg2Of induction,of
R7183 T9410 T9409 arg1Of induction,IL-10
R7184 T9413 T9411 arg2Of cells,in
R7185 T9413 T9412 arg1Of cells,Th1
R7186 T9414 T9404 arg2Of required,showed
R7187 T9414 T9405 arg1Of required,that
R7188 T9415 T9414 arg2Of stimulation,required
R7189 T9415 T9416 arg1Of stimulation,with
R7190 T9419 T9416 arg2Of dose,with
R7191 T9419 T9417 arg1Of dose,high
R7192 T9419 T9418 arg1Of dose,antigen
R7193 T9419 T9420 arg1Of dose,","
R7194 T9419 T9421 arg1Of dose,which
R7195 T9419 T9425 arg1Of dose,could
R7196 T9419 T9426 arg1Of dose,be
R7197 T9419 T9427 arg2Of dose,compensated
R7198 T9424 T9422 arg2Of extent,to
R7199 T9424 T9423 arg1Of extent,some
R72 T163 T161 arg1Of Factor,STAT4
R7200 T9427 T9422 arg1Of compensated,to
R7201 T9427 T9425 arg2Of compensated,could
R7202 T9427 T9426 arg2Of compensated,be
R7203 T9427 T9428 arg1Of compensated,for
R7204 T9427 T9429 arg1Of compensated,by
R7205 T9431 T9429 arg2Of addition,by
R7206 T9431 T9430 arg1Of addition,the
R7207 T9431 T9432 arg1Of addition,of
R7208 T9433 T9432 arg2Of IL-12,of
R7209 T9434 T9435 arg1Of Signaling,through
R7210 T9434 T9443 arg1Of Signaling,induced
R7211 T9437 T9435 arg2Of TCR,through
R7212 T9437 T9436 arg1Of TCR,the
R7213 T9437 T9438 arg1Of TCR,with
R7214 T9440 T9438 arg2Of doses,with
R7215 T9440 T9439 arg1Of doses,high
R7216 T9440 T9441 arg1Of doses,of
R7217 T9442 T9441 arg2Of antigen,of
R7218 T9443 T9459 arg1Of induced,in
R7219 T9443 T9468 arg1Of induced,as
R7220 T9443 T9479 arg1Of induced,in
R7221 T9445 T9444 arg1Of ERK1,stronger
R7222 T9445 T9446 arg1Of ERK1,and
R7223 T9446 T9443 arg2Of and,induced
R7224 T9446 T9449 arg1Of and,than
R7225 T9448 T9446 arg2Of activation,and
R7226 T9448 T9447 arg1Of activation,ERK2
R7227 T9450 T9449 arg2Of that,than
R7228 T9450 T9451 arg2Of that,induced
R7229 T9455 T9451 arg1Of dose,induced
R7230 T9455 T9452 arg2Of dose,by
R7231 T9455 T9453 arg1Of dose,low
R7232 T9455 T9454 arg1Of dose,antigen
R7233 T9458 T9456 arg1Of only,","
R7234 T9458 T9457 arg1Of only,not
R7235 T9459 T9458 arg1Of in,only
R7236 T9462 T9459 arg2Of T cells,in
R7237 T9462 T9460 arg1Of T cells,naive
R7238 T9462 T9461 arg1Of T cells,CD4+
R7239 T9462 T9463 arg1Of T cells,(
R7240 T9464 T9463 arg2Of data,(
R7241 T9464 T9466 arg2Of data,shown
R7242 T9466 T9465 arg1Of shown,not
R7243 T9467 T9463 arg3Of ),(
R7244 T9468 T9477 arg1Of as,but
R7245 T9470 T9469 arg1Of demonstrated,previously
R7246 T9473 T9468 arg2Of et al.,as
R7247 T9473 T9470 arg1Of et al.,demonstrated
R7248 T9473 T9471 arg2Of et al.,(
R7249 T9473 T9472 arg1Of et al.,Jorritsma
R7250 T9473 T9474 arg1Of et al.,","
R7251 T9475 T9474 arg2Of 2003,","
R7252 T9476 T9471 arg3Of ),(
R7253 T9477 T9478 arg1Of but,also
R7254 T9479 T9477 arg2Of in,but
R7255 T9481 T9479 arg2Of T cells,in
R7256 T9481 T9480 arg1Of T cells,CD4+
R7257 T9481 T9482 arg2Of T cells,restimulated
R7258 T9482 T9483 arg1Of restimulated,with
R7259 T9486 T9487 arg1Of high,and
R7260 T9488 T9487 arg2Of low,and
R7261 T9490 T9483 arg2Of doses,with
R7262 T9490 T9484 arg1Of doses,the
R7263 T9490 T9485 arg1Of doses,same
R7264 T9490 T9486 arg1Of doses,high
R7265 T9490 T9488 arg1Of doses,low
R7266 T9490 T9489 arg1Of doses,antigen
R7267 T9490 T9491 arg1Of doses,(
R7268 T9492 T9491 arg2Of Figure 5A,(
R7269 T9493 T9491 arg3Of ),(
R7270 T9497 T9498 arg1Of peak,and
R7271 T9498 T9495 arg1Of and,the
R7272 T9498 T9496 arg1Of and,apparent
R7273 T9498 T9500 arg1Of and,of
R7274 T9498 T9505 arg1Of and,varied
R7275 T9499 T9498 arg2Of amount,and
R7276 T9501 T9502 arg1Of ERK1,and
R7277 T9503 T9502 arg2Of ERK2,and
R7278 T9504 T9500 arg2Of activation,of
R7279 T9504 T9501 arg1Of activation,ERK1
R7280 T9504 T9503 arg1Of activation,ERK2
R7281 T9505 T9494 arg2Of varied,Although
R7282 T9505 T9506 arg1Of varied,slightly
R7283 T9505 T9507 arg1Of varied,between
R7284 T9508 T9507 arg2Of experiments,between
R7285 T9512 T9510 arg1Of finding,a
R7286 T9512 T9511 arg1Of finding,consistent
R7287 T9512 T9513 arg1Of finding,was
R7288 T9513 T9494 arg1Of was,Although
R7289 T9513 T9509 arg1Of was,","
R7290 T9517 T9515 arg1Of dose,high
R7291 T9517 T9516 arg1Of dose,antigen
R7292 T9517 T9518 arg1Of dose,differentiated
R7293 T9518 T9513 arg2Of differentiated,was
R7294 T9518 T9514 arg1Of differentiated,that
R7295 T9519 T9522 modOf Th1,showed
R7296 T9519 T9537 arg1Of Th1,of
R7297 T9520 T9522 arg1Of cells,showed
R7298 T9522 T9521 arg1Of showed,always
R7299 T9522 T9535 arg1Of showed,","
R73 T163 T162 arg1Of Factor,Transcription
R7300 T9522 T9536 arg1Of showed,regardless
R7301 T9523 T9524 arg1Of enhanced,and
R7302 T9525 T9524 arg2Of prolonged,and
R7303 T9526 T9523 arg1Of ERK1,enhanced
R7304 T9526 T9525 arg1Of ERK1,prolonged
R7305 T9526 T9527 arg1Of ERK1,and
R7306 T9527 T9522 arg2Of and,showed
R7307 T9527 T9530 arg1Of and,in
R7308 T9529 T9527 arg2Of activation,and
R7309 T9529 T9528 arg1Of activation,ERK2
R7310 T9532 T9530 arg2Of presence,in
R7311 T9532 T9531 arg1Of presence,the
R7312 T9532 T9533 arg1Of presence,of
R7313 T9534 T9533 arg2Of IL-12,of
R7314 T9539 T9540 arg1Of they,were
R7315 T9539 T9541 arg2Of they,restimulated
R7316 T9541 T9537 arg2Of restimulated,of
R7317 T9541 T9538 arg1Of restimulated,whether
R7318 T9541 T9540 arg2Of restimulated,were
R7319 T9541 T9542 arg1Of restimulated,with
R7320 T9543 T9542 arg2Of high,with
R7321 T9547 T9518 arg2Of dose,differentiated
R7322 T9547 T9519 arg1Of dose,Th1
R7323 T9547 T9544 arg1Of dose,or
R7324 T9547 T9545 arg1Of dose,low
R7325 T9547 T9546 arg1Of dose,antigen
R7326 T9547 T9548 arg1Of dose,(
R7327 T9549 T9548 arg2Of Figure 5B,(
R7328 T9550 T9548 arg3Of ),(
R7329 T9551 T9553 arg1Of We,investigated
R7330 T9553 T9552 arg1Of investigated,then
R7331 T9555 T9556 arg1Of ERK1,and
R7332 T9557 T9556 arg2Of ERK2,and
R7333 T9558 T9555 arg1Of activation,ERK1
R7334 T9558 T9557 arg1Of activation,ERK2
R7335 T9558 T9559 arg1Of activation,was
R7336 T9558 T9560 arg2Of activation,required
R7337 T9558 T9570 arg1Of activation,using
R7338 T9560 T9553 arg2Of required,investigated
R7339 T9560 T9554 arg1Of required,whether
R7340 T9560 T9559 arg2Of required,was
R7341 T9560 T9561 arg1Of required,for
R7342 T9560 T9569 arg1Of required,by
R7343 T9563 T9561 arg2Of induction,for
R7344 T9563 T9562 arg1Of induction,the
R7345 T9563 T9564 arg1Of induction,of
R7346 T9563 T9566 arg1Of induction,in
R7347 T9565 T9564 arg2Of IL-10,of
R7348 T9568 T9566 arg2Of cells,in
R7349 T9568 T9567 arg1Of cells,Th1
R7350 T9570 T9569 arg2Of using,by
R7351 T9571 T9570 arg2Of U0126,using
R7352 T9571 T9572 arg1Of U0126,(
R7353 T9571 T9575 arg1Of U0126,","
R7354 T9573 T9572 arg2Of Figure 5C,(
R7355 T9574 T9572 arg3Of ),(
R7356 T9577 T9575 arg2Of compound,","
R7357 T9577 T9576 arg1Of compound,a
R7358 T9577 T9578 arg1Of compound,that
R7359 T9577 T9579 arg1Of compound,blocks
R7360 T9582 T9579 arg2Of activation,blocks
R7361 T9582 T9580 arg1Of activation,downstream
R7362 T9582 T9581 arg1Of activation,ERK
R7363 T9584 T9583 arg1Of ensure,To
R7364 T9588 T9586 arg1Of signaling,only
R7365 T9588 T9587 arg1Of signaling,T cell
R7366 T9588 T9589 arg1Of signaling,was
R7367 T9588 T9590 arg1Of signaling,being
R7368 T9588 T9591 arg2Of signaling,affected
R7369 T9591 T9584 arg2Of affected,ensure
R7370 T9591 T9585 arg1Of affected,that
R7371 T9591 T9589 arg2Of affected,was
R7372 T9591 T9590 arg2Of affected,being
R7373 T9593 T9591 arg1Of U0126,affected
R7374 T9593 T9592 arg2Of U0126,by
R7375 T9595 T9584 arg1Of we,ensure
R7376 T9595 T9596 arg1Of we,used
R7377 T9596 T9583 modOf used,To
R7378 T9596 T9594 arg1Of used,","
R7379 T9599 T9596 arg2Of system,used
R7380 T9599 T9597 arg1Of system,an
R7381 T9599 T9598 arg1Of system,APC-free
R7382 T9599 T9600 arg2Of system,in
R7383 T9599 T9601 arg1Of system,which
R7384 T9603 T9602 arg1Of T cells,the
R7385 T9603 T9604 arg1Of T cells,were
R7386 T9603 T9605 arg2Of T cells,differentiated
R7387 T9605 T9600 arg1Of differentiated,in
R7388 T9605 T9604 arg2Of differentiated,were
R7389 T9605 T9606 arg1Of differentiated,in
R7390 T9608 T9607 arg1Of presence,the
R7391 T9608 T9609 arg1Of presence,of
R7392 T9608 T9614 arg1Of presence,and
R7393 T9611 T9609 arg2Of doses,of
R7394 T9611 T9610 arg1Of doses,increasing
R7395 T9611 T9612 arg1Of doses,of
R7396 T9613 T9612 arg2Of anti-CD3,of
R7397 T9614 T9606 arg2Of and,in
R7398 T9617 T9614 arg2Of amount,and
R7399 T9617 T9615 arg1Of amount,a
R74 T163 T164 arg1Of Factor,and
R7400 T9617 T9616 arg1Of amount,constant
R7401 T9617 T9618 arg1Of amount,of
R7402 T9619 T9618 arg2Of IL-12,of
R7403 T9621 T9620 arg1Of in,As
R7404 T9624 T9621 arg2Of cultures,in
R7405 T9624 T9622 arg1Of cultures,the
R7406 T9624 T9623 arg1Of cultures,APC-driven
R7407 T9628 T9626 arg1Of stimulation,stronger
R7408 T9628 T9627 arg1Of stimulation,TCR
R7409 T9628 T9629 arg1Of stimulation,together
R7410 T9628 T9632 arg1Of stimulation,led
R7411 T9629 T9630 arg1Of together,with
R7412 T9631 T9630 arg2Of IL-12,with
R7413 T9632 T9621 arg1Of led,in
R7414 T9632 T9625 arg1Of led,","
R7415 T9632 T9633 arg1Of led,to
R7416 T9635 T9633 arg2Of percentages,to
R7417 T9635 T9634 arg1Of percentages,higher
R7418 T9635 T9636 arg1Of percentages,of
R7419 T9637 T9636 arg2Of cells,of
R7420 T9637 T9638 arg1Of cells,producing
R7421 T9638 T9643 arg1Of producing,after
R7422 T9640 T9641 arg1Of IL-10,and
R7423 T9641 T9638 arg2Of and,producing
R7424 T9641 T9639 arg1Of and,both
R7425 T9642 T9641 arg2Of IFN-γ,and
R7426 T9645 T9643 arg2Of week,after
R7427 T9645 T9644 arg1Of week,1
R7428 T9645 T9646 arg1Of week,of
R7429 T9647 T9646 arg2Of culture,of
R7430 T9647 T9648 arg1Of culture,(
R7431 T9649 T9648 arg2Of Figure 5C,(
R7432 T9650 T9648 arg3Of ),(
R7433 T9651 T9652 arg1Of Addition,of
R7434 T9651 T9654 arg1Of Addition,to
R7435 T9651 T9657 arg1Of Addition,abrogated
R7436 T9653 T9652 arg2Of U0126,of
R7437 T9656 T9654 arg2Of cultures,to
R7438 T9656 T9655 arg1Of cultures,the
R7439 T9659 T9657 arg2Of production,abrogated
R7440 T9659 T9658 arg1Of production,the
R7441 T9659 T9660 arg1Of production,of
R7442 T9659 T9662 arg1Of production,at
R7443 T9661 T9660 arg2Of IL-10,of
R7444 T9664 T9662 arg2Of doses,at
R7445 T9664 T9663 arg1Of doses,all
R7446 T9664 T9665 arg1Of doses,of
R7447 T9666 T9665 arg2Of anti-CD3,of
R7448 T9666 T9667 arg1Of anti-CD3,(
R7449 T9668 T9667 arg2Of Figure 5C,(
R7450 T9669 T9667 arg3Of ),(
R7451 T9671 T9672 arg1Of U0126,inhibits
R7452 T9672 T9670 arg2Of inhibits,Because
R7453 T9675 T9673 arg1Of activation,the
R7454 T9675 T9674 arg1Of activation,MEK5-catalyzed
R7455 T9675 T9676 arg1Of activation,of
R7456 T9675 T9681 arg1Of activation,as
R7457 T9677 T9676 arg2Of ERK5,of
R7458 T9681 T9672 arg2Of as,inhibits
R7459 T9681 T9678 arg1Of as,","
R7460 T9681 T9679 arg1Of as,as
R7461 T9681 T9680 arg1Of as,well
R7462 T9683 T9684 arg1Of MEK1-,and
R7463 T9684 T9681 arg2Of and,as
R7464 T9684 T9682 arg1Of and,the
R7465 T9686 T9684 arg2Of activation,and
R7466 T9686 T9685 arg1Of activation,MEK2-catalyzed
R7467 T9686 T9687 arg1Of activation,of
R7468 T9688 T9689 arg1Of ERK1,and
R7469 T9689 T9687 arg2Of and,of
R7470 T9689 T9691 arg1Of and,(
R7471 T9690 T9689 arg2Of ERK2,and
R7472 T9693 T9692 arg1Of et al.,Bain
R7473 T9693 T9694 arg1Of et al.,","
R7474 T9693 T9696 arg1Of et al.,;
R7475 T9695 T9694 arg2Of 2007,","
R7476 T9696 T9691 arg2Of ;,(
R7477 T9698 T9696 arg2Of et al.,;
R7478 T9698 T9697 arg1Of et al.,Mody
R7479 T9698 T9699 arg1Of et al.,","
R7480 T9700 T9699 arg2Of 2001,","
R7481 T9701 T9691 arg3Of ),(
R7482 T9703 T9705 arg1Of we,used
R7483 T9705 T9670 arg1Of used,Because
R7484 T9705 T9702 arg1Of used,","
R7485 T9705 T9704 arg1Of used,also
R7486 T9705 T9717 arg1Of used,at
R7487 T9708 T9707 arg1Of specific,more
R7488 T9708 T9709 arg1Of specific,","
R7489 T9711 T9709 arg2Of unrelated,","
R7490 T9711 T9710 arg1Of unrelated,structurally
R7491 T9712 T9713 arg1Of MEK1,and
R7492 T9713 T9705 arg2Of and,used
R7493 T9713 T9706 arg1Of and,the
R7494 T9713 T9708 arg1Of and,specific
R7495 T9713 T9711 arg1Of and,unrelated
R7496 T9716 T9713 arg2Of PD184352,and
R7497 T9716 T9714 arg1Of PD184352,MEK2
R7498 T9716 T9715 arg1Of PD184352,inhibitor
R7499 T9718 T9717 arg2Of concentrations,at
R75 T164 T159 arg2Of and,Requires
R7500 T9718 T9719 arg2Of concentrations,in
R7501 T9718 T9720 arg1Of concentrations,which
R7502 T9721 T9722 arg1Of it,inhibits
R7503 T9722 T9719 arg1Of inhibits,in
R7504 T9723 T9724 arg1Of MEK1,and
R7505 T9724 T9726 arg1Of and,but
R7506 T9725 T9724 arg2Of MEK2,and
R7507 T9726 T9722 arg2Of but,inhibits
R7508 T9726 T9727 arg1Of but,not
R7509 T9728 T9726 arg2Of MEK5,but
R7510 T9728 T9729 arg1Of MEK5,(
R7511 T9731 T9730 arg1Of et al.,Bain
R7512 T9731 T9732 arg1Of et al.,","
R7513 T9731 T9734 arg1Of et al.,;
R7514 T9733 T9732 arg2Of 2007,","
R7515 T9734 T9729 arg2Of ;,(
R7516 T9736 T9734 arg2Of et al.,;
R7517 T9736 T9735 arg1Of et al.,Mody
R7518 T9736 T9737 arg1Of et al.,","
R7519 T9738 T9737 arg2Of 2001,","
R7520 T9739 T9729 arg3Of ),(
R7521 T9740 T9741 arg1Of PD184352,caused
R7522 T9741 T9751 arg1Of caused,in
R7523 T9744 T9741 arg2Of inhibition,caused
R7524 T9744 T9742 arg1Of inhibition,a
R7525 T9744 T9743 arg1Of inhibition,similar
R7526 T9744 T9745 arg1Of inhibition,of
R7527 T9744 T9748 arg1Of inhibition,by
R7528 T9747 T9745 arg2Of production,of
R7529 T9747 T9746 arg1Of production,IL-10
R7530 T9750 T9748 arg2Of cells,by
R7531 T9750 T9749 arg1Of cells,Th1
R7532 T9754 T9751 arg2Of fashion,in
R7533 T9754 T9752 arg1Of fashion,a
R7534 T9754 T9753 arg1Of fashion,dose-dependent
R7535 T9754 T9755 arg1Of fashion,(
R7536 T9756 T9757 arg1Of Figure 5D,and
R7537 T9757 T9755 arg2Of and,(
R7538 T9758 T9757 arg2Of Figure S5A,and
R7539 T9759 T9755 arg3Of ),(
R7540 T9761 T9760 arg2Of addition,Upon
R7541 T9761 T9762 arg1Of addition,of
R7542 T9761 T9764 arg1Of addition,to
R7543 T9763 T9762 arg2Of inhibitors,of
R7544 T9766 T9764 arg2Of pathways,to
R7545 T9766 T9765 arg1Of pathways,other signaling
R7546 T9766 T9767 arg1Of pathways,","
R7547 T9766 T9768 arg1Of pathways,including
R7548 T9772 T9769 arg1Of inhibitor,a
R7549 T9772 T9770 arg1Of inhibitor,p38
R7550 T9772 T9771 arg1Of inhibitor,MAPK
R7551 T9772 T9773 arg1Of inhibitor,","
R7552 T9772 T9776 arg1Of inhibitor,or
R7553 T9774 T9773 arg2Of SB203580,","
R7554 T9776 T9768 arg2Of or,including
R7555 T9776 T9775 arg1Of or,","
R7556 T9779 T9776 arg2Of inhibitor,or
R7557 T9779 T9777 arg1Of inhibitor,the
R7558 T9779 T9778 arg1Of inhibitor,GSK3β
R7559 T9779 T9780 arg1Of inhibitor,","
R7560 T9781 T9780 arg2Of CT99021,","
R7561 T9781 T9782 arg1Of CT99021,(
R7562 T9784 T9782 arg2Of et al.,(
R7563 T9784 T9783 arg1Of et al.,Bain
R7564 T9784 T9785 arg1Of et al.,","
R7565 T9786 T9785 arg2Of 2007,","
R7566 T9787 T9782 arg3Of ),(
R7567 T9790 T9789 arg1Of effect,no
R7568 T9790 T9791 arg1Of effect,on
R7569 T9790 T9794 arg1Of effect,was
R7570 T9790 T9795 arg2Of effect,observed
R7571 T9793 T9791 arg2Of production,on
R7572 T9793 T9792 arg1Of production,IL-10
R7573 T9795 T9760 arg1Of observed,Upon
R7574 T9795 T9788 arg1Of observed,","
R7575 T9795 T9794 arg2Of observed,was
R7576 T9795 T9796 arg1Of observed,(
R7577 T9797 T9796 arg2Of Figure S5B,(
R7578 T9798 T9796 arg3Of ),(
R7579 T9800 T9799 arg1Of data,Our
R7580 T9800 T9802 arg1Of data,suggested
R7581 T9802 T9801 arg1Of suggested,thus
R7582 T9805 T9804 arg1Of production,IL-10
R7583 T9805 T9806 arg1Of production,by
R7584 T9805 T9817 arg1Of production,requires
R7585 T9808 T9806 arg2Of cells,by
R7586 T9808 T9807 arg1Of cells,Th1
R7587 T9808 T9809 arg1Of cells,in
R7588 T9810 T9809 arg2Of response,in
R7589 T9810 T9811 arg1Of response,to
R7590 T9814 T9812 arg1Of dose,high
R7591 T9814 T9813 arg1Of dose,antigen
R7592 T9814 T9815 arg1Of dose,and
R7593 T9815 T9811 arg2Of and,to
R7594 T9816 T9815 arg2Of IL-12,and
R7595 T9817 T9802 arg2Of requires,suggested
R7596 T9817 T9803 arg1Of requires,that
R7597 T9818 T9819 arg1Of ERK1,and
R7598 T9819 T9823 arg1Of and,but
R7599 T9821 T9819 arg2Of signaling,and
R76 T164 T169 arg1Of and,by
R7600 T9821 T9820 arg1Of signaling,ERK2
R7601 T9823 T9817 arg2Of but,requires
R7602 T9823 T9822 arg1Of but,","
R7603 T9823 T9824 arg1Of but,not
R7604 T9826 T9823 arg2Of activation,but
R7605 T9826 T9825 arg1Of activation,the
R7606 T9826 T9827 arg1Of activation,of
R7607 T9829 T9828 arg1Of p38,the
R7608 T9829 T9830 arg1Of p38,or
R7609 T9830 T9827 arg2Of or,of
R7610 T9833 T9830 arg2Of pathways,or
R7611 T9833 T9831 arg1Of pathways,the
R7612 T9833 T9832 arg1Of pathways,GSK3β
R77 T168 T164 arg2Of Activation,and
R78 T168 T165 arg1Of Activation,ERK
R79 T168 T166 arg1Of Activation,MAP
R80 T168 T167 arg1Of Activation,Kinase
R81 T172 T169 arg2Of Dose,by
R82 T172 T170 arg1Of Dose,High
R83 T172 T171 arg1Of Dose,Antigen
R84 T175 T174 arg1Of T cells,CD4+
R8485 T11028 T11027 arg1Of Production,IL-10
R8486 T11028 T11029 arg1Of Production,by
R8487 T11028 T11035 arg1Of Production,Requires
R8488 T11030 T11031 arg1Of Th2,and
R8489 T11032 T11031 arg2Of Th17,and
R8490 T11033 T11029 arg2Of Cells,by
R8491 T11033 T11030 arg1Of Cells,Th2
R8492 T11033 T11032 arg1Of Cells,Th17
R8493 T11035 T11034 arg1Of Requires,Also
R8494 T11036 T11037 arg1Of ERK1,and
R8495 T11038 T11037 arg2Of ERK2,and
R8496 T11039 T11035 arg2Of Activation,Requires
R8497 T11039 T11036 arg1Of Activation,ERK1
R8498 T11039 T11038 arg1Of Activation,ERK2
R8499 T11041 T11040 arg1Of address,To
R85 T175 T176 arg1Of T cells,producing
R8500 T11041 T11042 arg1Of address,whether
R8501 T11044 T11043 arg1Of production,IL-10
R8502 T11044 T11045 arg1Of production,by
R8503 T11044 T11050 arg1Of production,was
R8504 T11044 T11052 arg1Of production,dependent
R8505 T11046 T11047 arg1Of Th2,and
R8506 T11048 T11047 arg2Of Th17,and
R8507 T11049 T11045 arg2Of cells,by
R8508 T11049 T11046 arg1Of cells,Th2
R8509 T11049 T11048 arg1Of cells,Th17
R8510 T11050 T11042 arg2Of was,whether
R8511 T11050 T11051 arg1Of was,also
R8512 T11050 T11055 arg1Of was,and
R8513 T11052 T11050 arg2Of dependent,was
R8514 T11052 T11053 arg1Of dependent,on
R8515 T11054 T11053 arg2Of ERK1,on
R8516 T11056 T11041 arg2Of ERK2,address
R8517 T11057 T11041 arg1Of activation,address
R8518 T11057 T11058 arg1Of activation,","
R8519 T11057 T11060 arg1Of activation,differentiated
R8520 T11059 T11058 arg2Of we,","
R8521 T11060 T11040 modOf differentiated,To
R8522 T11060 T11063 arg1Of differentiated,with
R8523 T11060 T11067 arg1Of differentiated,in
R8524 T11060 T11088 arg1Of differentiated,","
R8525 T11060 T11089 arg1Of differentiated,in
R8526 T11062 T11060 arg2Of cells,differentiated
R8527 T11062 T11061 arg1Of cells,these
R8528 T11064 T11065 arg1Of anti-CD3,and
R8529 T11065 T11063 arg2Of and,with
R8530 T11066 T11065 arg2Of anti-CD28,and
R8531 T11069 T11067 arg2Of absence,in
R8532 T11069 T11068 arg1Of absence,the
R8533 T11069 T11070 arg1Of absence,of
R8534 T11071 T11070 arg2Of APCs,of
R8535 T11071 T11072 arg1Of APCs,(
R8536 T11074 T11073 arg1Of et al.,Shoemaker
R8537 T11074 T11075 arg1Of et al.,","
R8538 T11074 T11077 arg1Of et al.,;
R8539 T11076 T11075 arg2Of 2006,","
R8540 T11077 T11082 arg1Of ;,;
R8541 T11078 T11077 arg2Of Veldhoen,;
R8542 T11078 T11079 arg1Of Veldhoen,et al.
R8543 T11078 T11080 arg1Of Veldhoen,","
R8544 T11081 T11080 arg2Of 2009,","
R8545 T11082 T11072 arg2Of ;,(
R8546 T11083 T11082 arg2Of Veldhoen,;
R8547 T11083 T11084 arg1Of Veldhoen,et al.
R8548 T11083 T11085 arg1Of Veldhoen,","
R8549 T11086 T11085 arg2Of 2006,","
R8550 T11087 T11072 arg3Of ),(
R8551 T11091 T11092 arg1Of presence,or
R8552 T11092 T11089 arg2Of or,in
R8553 T11092 T11090 arg1Of or,the
R8554 T11092 T11094 arg1Of or,of
R8555 T11093 T11092 arg2Of absence,or
R8556 T11097 T11094 arg2Of inhibitor,of
R8557 T11097 T11095 arg1Of inhibitor,the
R8558 T11097 T11096 arg1Of inhibitor,MEK
R8559 T11097 T11098 arg1Of inhibitor,(
R8560 T11099 T11098 arg2Of PD184352,(
R8561 T11100 T11098 arg3Of ),(
R8562 T11101 T11102 arg1Of We,showed
R8563 T11104 T11105 arg1Of ERK1,and
R8564 T11105 T11108 arg1Of and,is
R8565 T11107 T11105 arg2Of activation,and
R8566 T11107 T11106 arg1Of activation,ERK2
R8567 T11108 T11102 arg2Of is,showed
R8568 T11108 T11103 arg1Of is,that
R8569 T11111 T11108 arg2Of pathway,is
R8570 T11111 T11109 arg1Of pathway,a
R8571 T11111 T11110 arg1Of pathway,common
R8572 T11111 T11112 arg2Of pathway,required
R8573 T11112 T11113 arg1Of required,for
R8574 T11112 T11122 arg1Of required,because
R8575 T11114 T11113 arg2Of induction,for
R8576 T11114 T11115 arg1Of induction,of
R8577 T11114 T11117 arg1Of induction,in
R8578 T11116 T11115 arg2Of IL-10,of
R8579 T11121 T11117 arg2Of subsets,in
R8580 T11121 T11118 arg1Of subsets,different
R8581 T11121 T11119 arg1Of subsets,Th
R8582 T11121 T11120 arg1Of subsets,cell
R8583 T11124 T11123 arg1Of production,IL-10
R8584 T11124 T11125 arg1Of production,by
R8585 T11124 T11131 arg1Of production,was
R8586 T11124 T11133 arg2Of production,inhibited
R8587 T11127 T11128 arg1Of Th2,and
R8588 T11128 T11126 arg1Of and,both
R8589 T11129 T11128 arg2Of Th17,and
R8590 T11130 T11125 arg2Of cells,by
R8591 T11130 T11127 arg1Of cells,Th2
R8592 T11130 T11129 arg1Of cells,Th17
R8593 T11133 T11122 arg2Of inhibited,because
R8594 T11133 T11131 arg2Of inhibited,was
R8595 T11133 T11132 arg1Of inhibited,markedly
R8596 T11133 T11134 arg1Of inhibited,in
R8597 T11136 T11134 arg2Of presence,in
R8598 T11136 T11135 arg1Of presence,the
R8599 T11136 T11137 arg1Of presence,of
R86 T175 T186 arg1Of T cells,are
R8600 T11140 T11137 arg2Of inhibitor,of
R8601 T11140 T11138 arg1Of inhibitor,the
R8602 T11140 T11139 arg1Of inhibitor,MEK
R8603 T11140 T11141 arg1Of inhibitor,(
R8604 T11140 T11144 arg1Of inhibitor,(
R8605 T11142 T11141 arg2Of PD184352,(
R8606 T11143 T11141 arg3Of ),(
R8607 T11145 T11146 arg1Of Figure 5D,and
R8608 T11146 T11144 arg2Of and,(
R8609 T11147 T11146 arg2Of Figure S5B,and
R8610 T11148 T11144 arg3Of ),(
R8611 T11150 T11149 arg2Of contrast,In
R8612 T11152 T11153 arg1Of inhibitors,of
R8613 T11152 T11157 arg1Of inhibitors,of
R8614 T11152 T11160 arg1Of inhibitors,did
R8615 T11152 T11162 arg1Of inhibitors,affect
R8616 T11153 T11156 arg1Of of,or
R8617 T11155 T11153 arg2Of MAPK,of
R8618 T11155 T11154 arg1Of MAPK,p38
R8619 T11157 T11156 arg2Of of,or
R8620 T11159 T11157 arg2Of activation,of
R8621 T11159 T11158 arg1Of activation,GSK-3β
R8622 T11162 T11149 arg1Of affect,In
R8623 T11162 T11151 arg1Of affect,","
R8624 T11162 T11160 arg2Of affect,did
R8625 T11162 T11161 arg1Of affect,not
R8626 T11164 T11162 arg2Of expression,affect
R8627 T11164 T11163 arg1Of expression,the
R8628 T11164 T11165 arg1Of expression,of
R8629 T11164 T11167 arg1Of expression,by
R8630 T11164 T11170 arg1Of expression,(
R8631 T11166 T11165 arg2Of IL-10,of
R8632 T11169 T11167 arg2Of subsets,by
R8633 T11169 T11168 arg1Of subsets,these
R8634 T11171 T11170 arg2Of Figure S5B,(
R8635 T11172 T11170 arg3Of ),(
R8636 T11173 T11174 arg1Of Activation,of
R8637 T11173 T11181 arg1Of Activation,is
R8638 T11176 T11177 arg1Of ERK1,and
R8639 T11178 T11177 arg2Of ERK2,and
R8640 T11180 T11174 arg2Of pathway,of
R8641 T11180 T11175 arg1Of pathway,the
R8642 T11180 T11176 arg1Of pathway,ERK1
R8643 T11180 T11178 arg1Of pathway,ERK2
R8644 T11180 T11179 arg1Of pathway,signaling
R8645 T11181 T11182 arg1Of is,therefore
R8646 T11185 T11181 arg2Of requirement,is
R8647 T11185 T11183 arg1Of requirement,a
R8648 T11185 T11184 arg1Of requirement,common
R8649 T11185 T11186 arg1Of requirement,for
R8650 T11188 T11186 arg2Of induction,for
R8651 T11188 T11187 arg1Of induction,the
R8652 T11188 T11189 arg1Of induction,of
R8653 T11188 T11192 arg1Of induction,by
R8654 T11191 T11189 arg2Of production,of
R8655 T11191 T11190 arg1Of production,IL-10
R8656 T11193 T11194 arg1Of Th1,","
R8657 T11194 T11197 arg1Of ",",and
R8658 T11195 T11194 arg2Of Th2,","
R8659 T11197 T11196 arg1Of and,","
R8660 T11198 T11197 arg2Of Th17,and
R8661 T11199 T11192 arg2Of cells,by
R8662 T11199 T11193 arg1Of cells,Th1
R8663 T11199 T11195 arg1Of cells,Th2
R8664 T11199 T11198 arg1Of cells,Th17
R87 T175 T187 arg2Of T cells,reported
R88 T177 T178 arg1Of interleukin-10,(
R89 T177 T181 arg1Of interleukin-10,and
R90 T179 T178 arg2Of IL-10,(
R91 T180 T178 arg3Of ),(
R92 T181 T176 arg2Of and,producing
R9214 T11959 T11958 arg1Of Expression,c-maf
R9215 T11959 T11960 arg1Of Expression,Correlates
R9216 T11960 T11961 arg1Of Correlates,with
R9217 T11963 T11961 arg2Of Production,with
R9218 T11963 T11962 arg1Of Production,IL-10
R9219 T11963 T11964 arg1Of Production,in
R9220 T11965 T11966 arg1Of Th1,","
R9221 T11966 T11969 arg1Of ",",and
R9222 T11967 T11966 arg2Of Th2,","
R9223 T11969 T11968 arg1Of and,","
R9224 T11970 T11969 arg2Of Th17,and
R9225 T11971 T11964 arg2Of Cells,in
R9226 T11971 T11965 arg1Of Cells,Th1
R9227 T11971 T11967 arg1Of Cells,Th2
R9228 T11971 T11970 arg1Of Cells,Th17
R9229 T11973 T11972 arg1Of investigate,To
R9230 T11973 T11974 arg1Of investigate,further
R9231 T11977 T11973 arg2Of factors,investigate
R9232 T11977 T11975 arg1Of factors,the
R9233 T11977 T11976 arg1Of factors,downstream
R9234 T11977 T11978 arg2Of factors,involved
R9235 T11978 T11979 arg1Of involved,in
R9236 T11980 T11979 arg2Of regulating,in
R9237 T11982 T11980 arg2Of production,regulating
R9238 T11982 T11981 arg1Of production,IL-10
R9239 T11984 T11985 arg1Of we,differentiated
R9240 T11984 T12004 arg1Of we,quantified
R9241 T11985 T11994 arg1Of differentiated,","
R9242 T11985 T11995 arg1Of differentiated,in
R9243 T11985 T12003 arg1Of differentiated,and
R9244 T11988 T11985 arg2Of T cells,differentiated
R9245 T11988 T11986 arg1Of T cells,DO11.10
R9246 T11988 T11987 arg1Of T cells,CD4+
R9247 T11988 T11989 arg1Of T cells,with
R9248 T11991 T11989 arg2Of doses,with
R9249 T11991 T11990 arg1Of doses,increasing
R9250 T11991 T11992 arg1Of doses,of
R9251 T11993 T11992 arg2Of OVA,of
R9252 T11997 T11998 arg1Of presence,or
R9253 T11998 T11995 arg2Of or,in
R9254 T11998 T11996 arg1Of or,the
R9255 T11998 T12000 arg1Of or,of
R9256 T11999 T11998 arg2Of absence,or
R9257 T12001 T12000 arg2Of IL-12,of
R9258 T12003 T11972 modOf and,To
R9259 T12003 T11983 arg1Of and,","
R9260 T12003 T12002 arg1Of and,","
R9261 T12004 T12003 arg2Of quantified,and
R9262 T12004 T12012 arg1Of quantified,by
R9263 T12006 T12004 arg2Of expression,quantified
R9264 T12006 T12005 arg1Of expression,the
R9265 T12006 T12007 arg1Of expression,of
R9266 T12008 T12009 arg1Of cytokines,and
R9267 T12009 T12007 arg2Of and,of
R9268 T12011 T12009 arg2Of factors,and
R9269 T12011 T12010 arg1Of factors,transcription
R9270 T12014 T12012 arg2Of RT-PCR,by
R9271 T12014 T12013 arg1Of RT-PCR,real-time
R9272 T12016 T12015 arg1Of antigen,Low-dose
R9273 T12016 T12017 arg1Of antigen,resulted
R9274 T12017 T12018 arg1Of resulted,in
R9275 T12017 T12022 arg1Of resulted,and
R9276 T12019 T12018 arg2Of transcription,in
R9277 T12019 T12020 arg1Of transcription,of
R9278 T12021 T12020 arg2Of Il4,of
R9279 T12023 T12024 arg1Of this,was
R9280 T12023 T12025 arg2Of this,abrogated
R9281 T12025 T12022 arg2Of abrogated,and
R9282 T12025 T12024 arg2Of abrogated,was
R9283 T12030 T12028 arg1Of doses,high
R9284 T12030 T12029 arg1Of doses,antigen
R9285 T12030 T12031 arg1Of doses,and
R9286 T12031 T12025 arg1Of and,abrogated
R9287 T12031 T12026 arg2Of and,by
R9288 T12031 T12027 arg1Of and,both
R9289 T12032 T12031 arg2Of IL-12,and
R9290 T12032 T12033 arg1Of IL-12,(
R9291 T12034 T12033 arg2Of Figure 6A,(
R9292 T12035 T12033 arg3Of ),(
R9293 T12038 T12036 arg1Of amount,A
R9294 T12038 T12037 arg1Of amount,low
R9295 T12038 T12039 arg1Of amount,of
R9296 T12038 T12043 arg1Of amount,was
R9297 T12038 T12044 arg2Of amount,induced
R9298 T12040 T12039 arg2Of transcription,of
R9299 T12040 T12041 arg1Of transcription,of
R93 T182 T181 arg2Of interferon-γ,and
R9300 T12042 T12041 arg2Of Ifnγ,of
R9301 T12044 T12043 arg2Of induced,was
R9302 T12044 T12045 arg1Of induced,by
R9303 T12044 T12047 arg1Of induced,when
R9304 T12044 T12056 arg1Of induced,but
R9305 T12046 T12045 arg2Of IL-12,by
R9306 T12048 T12049 arg1Of cells,were
R9307 T12048 T12050 arg2Of cells,differentiated
R9308 T12050 T12047 arg2Of differentiated,when
R9309 T12050 T12049 arg2Of differentiated,were
R9310 T12050 T12051 arg1Of differentiated,with
R9311 T12054 T12051 arg2Of dose,with
R9312 T12054 T12052 arg1Of dose,low
R9313 T12054 T12053 arg1Of dose,antigen
R9314 T12056 T12055 arg1Of but,","
R9315 T12058 T12057 arg1Of effect,this
R9316 T12058 T12059 arg1Of effect,of
R9317 T12058 T12061 arg1Of effect,was
R9318 T12058 T12063 arg2Of effect,upregulated
R9319 T12060 T12059 arg2Of IL-12,of
R9320 T12063 T12056 arg2Of upregulated,but
R9321 T12063 T12061 arg2Of upregulated,was
R9322 T12063 T12062 arg1Of upregulated,markedly
R9323 T12063 T12064 arg1Of upregulated,with
R9324 T12066 T12064 arg2Of doses,with
R9325 T12066 T12065 arg1Of doses,increasing
R9326 T12066 T12067 arg1Of doses,of
R9327 T12068 T12067 arg2Of antigen,of
R9328 T12068 T12069 arg1Of antigen,(
R9329 T12070 T12069 arg2Of Figure 6A,(
R9330 T12071 T12069 arg3Of ),(
R9331 T12074 T12072 arg1Of amount,A
R9332 T12074 T12073 arg1Of amount,low
R9333 T12074 T12075 arg1Of amount,of
R9334 T12074 T12078 arg1Of amount,was
R9335 T12074 T12079 arg2Of amount,observed
R9336 T12077 T12075 arg2Of transcription,of
R9337 T12077 T12076 arg1Of transcription,Il10
R9338 T12079 T12078 arg2Of observed,was
R9339 T12079 T12080 arg1Of observed,at
R9340 T12079 T12094 arg1Of observed,and
R9341 T12082 T12080 arg2Of doses,at
R9342 T12082 T12081 arg1Of doses,low
R9343 T12082 T12083 arg1Of doses,of
R9344 T12087 T12083 arg2Of expression,of
R9345 T12087 T12084 arg1Of expression,antigen
R9346 T12087 T12085 arg1Of expression,accompanying
R9347 T12087 T12086 arg1Of expression,Il4
R9348 T12087 T12088 arg1Of expression,(
R9349 T12091 T12088 arg2Of response,(
R9350 T12091 T12089 arg1Of response,Th2
R9351 T12091 T12090 arg1Of response,cell
R9352 T12092 T12088 arg3Of ),(
R9353 T12094 T12093 arg1Of and,","
R9354 T12095 T12096 arg1Of this,was
R9355 T12095 T12097 arg2Of this,abrogated
R9356 T12097 T12094 arg2Of abrogated,and
R9357 T12097 T12096 arg2Of abrogated,was
R9358 T12097 T12103 arg1Of abrogated,as
R9359 T12100 T12097 arg1Of doses,abrogated
R9360 T12100 T12098 arg2Of doses,by
R9361 T12100 T12099 arg2Of doses,increased
R9362 T12100 T12101 arg1Of doses,of
R9363 T12102 T12101 arg2Of antigen,of
R9364 T12104 T12103 arg2Of was,as
R9365 T12106 T12104 arg1Of expression,was
R9366 T12106 T12105 arg1Of expression,Il4
R9367 T12106 T12107 arg1Of expression,(
R9368 T12108 T12107 arg2Of Figure 6A,(
R9369 T12109 T12107 arg3Of ),(
R9370 T12112 T12110 arg2Of doses,At
R9371 T12112 T12111 arg1Of doses,low
R9372 T12112 T12113 arg1Of doses,of
R9373 T12114 T12113 arg2Of antigen,of
R9374 T12116 T12117 arg1Of IL-12,had
R9375 T12117 T12110 arg1Of had,At
R9376 T12117 T12115 arg1Of had,","
R9377 T12117 T12120 modOf had,to
R9378 T12119 T12117 arg2Of effect,had
R9379 T12119 T12118 arg1Of effect,little
R9380 T12121 T12120 arg1Of increase,to
R9381 T12124 T12121 arg2Of expression,increase
R9382 T12124 T12122 arg1Of expression,IL-10
R9383 T12124 T12123 arg1Of expression,mRNA
R9384 T12124 T12125 arg1Of expression,(
R9385 T12124 T12128 arg1Of expression,in
R9386 T12126 T12125 arg2Of Figure 6A,(
R9387 T12127 T12125 arg3Of ),(
R9388 T12129 T12128 arg2Of keeping,in
R9389 T12129 T12130 arg1Of keeping,with
R9390 T12133 T12130 arg2Of data,with
R9391 T12133 T12131 arg1Of data,the
R9392 T12133 T12132 arg1Of data,protein
R9393 T12133 T12134 arg1Of data,(
R9394 T12135 T12134 arg2Of Figure 1A,(
R9395 T12136 T12134 arg3Of ),(
R9396 T12139 T12140 arg1Of IL-12,induced
R9397 T12140 T12137 arg1Of induced,However
R9398 T12140 T12138 arg1Of induced,","
R9399 T12140 T12159 arg1Of induced,","
R94 T182 T183 arg1Of interferon-γ,(
R9400 T12140 T12161 arg1Of induced,in
R9401 T12143 T12141 arg1Of amount,a
R9402 T12143 T12142 arg1Of amount,high
R9403 T12143 T12144 arg1Of amount,of
R9404 T12143 T12149 arg1Of amount,as
R9405 T12146 T12144 arg2Of transcription,of
R9406 T12146 T12145 arg1Of transcription,Il10
R9407 T12149 T12140 arg2Of as,induced
R9408 T12149 T12147 arg1Of as,as
R9409 T12149 T12148 arg1Of as,well
R9410 T12151 T12149 arg2Of expression,as
R9411 T12151 T12150 arg1Of expression,Ifnγ
R9412 T12151 T12152 arg1Of expression,with
R9413 T12155 T12152 arg2Of doses,with
R9414 T12155 T12153 arg2Of doses,increased
R9415 T12155 T12154 arg1Of doses,antigen
R9416 T12155 T12156 arg1Of doses,(
R9417 T12157 T12156 arg2Of Figure 6A,(
R9418 T12158 T12156 arg3Of ),(
R9419 T12161 T12160 arg1Of in,again
R9420 T12162 T12161 arg2Of keeping,in
R9421 T12162 T12163 arg1Of keeping,with
R9422 T12166 T12163 arg2Of data,with
R9423 T12166 T12164 arg1Of data,the
R9424 T12166 T12165 arg1Of data,protein
R9425 T12166 T12167 arg1Of data,(
R9426 T12168 T12167 arg2Of Figure 1A,(
R9427 T12169 T12167 arg3Of ),(
R9428 T12171 T12170 arg1Of T cells,CD4+
R9429 T12171 T12172 arg2Of T cells,differentiated
R9430 T12171 T12178 arg1Of T cells,did
R9431 T12171 T12180 arg1Of T cells,express
R9432 T12172 T12173 arg1Of differentiated,with
R9433 T12175 T12173 arg2Of doses,with
R9434 T12175 T12174 arg1Of doses,increasing
R9435 T12175 T12176 arg1Of doses,of
R9436 T12177 T12176 arg2Of antigen,of
R9437 T12180 T12178 arg2Of express,did
R9438 T12180 T12179 arg1Of express,not
R9439 T12180 T12189 arg1Of express,","
R9440 T12180 T12190 arg1Of express,unless
R9441 T12182 T12180 arg2Of amounts,express
R9442 T12182 T12181 arg1Of amounts,high
R9443 T12182 T12183 arg1Of amounts,of
R9444 T12186 T12185 arg2Of T-bet,(
R9445 T12187 T12185 arg3Of ),(
R9446 T12188 T12183 arg2Of mRNA,of
R9447 T12188 T12184 arg1Of mRNA,Tbx-21
R9448 T12188 T12185 arg1Of mRNA,(
R9449 T12191 T12192 arg1Of they,were
R9450 T12191 T12193 arg2Of they,cocultured
R9451 T12193 T12190 arg2Of cocultured,unless
R9452 T12193 T12192 arg2Of cocultured,were
R9453 T12193 T12194 arg1Of cocultured,with
R9454 T12195 T12194 arg2Of IL-12,with
R9455 T12195 T12196 arg1Of IL-12,(
R9456 T12197 T12196 arg2Of Figure 6B,(
R9457 T12198 T12196 arg3Of ),(
R9458 T12200 T12199 arg2Of contrast,In
R9459 T12203 T12202 arg1Of amounts,high
R9460 T12203 T12204 arg1Of amounts,of
R9461 T12203 T12208 arg1Of amounts,were
R9462 T12203 T12210 arg2Of amounts,observed
R9463 T12207 T12204 arg2Of expression,of
R9464 T12207 T12205 arg1Of expression,GATA-3
R9465 T12207 T12206 arg1Of expression,mRNA
R9466 T12210 T12208 arg2Of observed,were
R9467 T12210 T12209 arg1Of observed,only
R9468 T12210 T12211 arg1Of observed,under
R9469 T12210 T12224 arg1Of observed,and
R9470 T12215 T12211 arg2Of conditions,under
R9471 T12215 T12212 arg1Of conditions,Th2
R9472 T12215 T12213 arg1Of conditions,cell
R9473 T12215 T12214 arg1Of conditions,differentiation
R9474 T12215 T12216 arg1Of conditions,(
R9475 T12215 T12220 arg1Of conditions,(
R9476 T12218 T12216 arg2Of antigen,(
R9477 T12218 T12217 arg1Of antigen,low-dose
R9478 T12219 T12216 arg3Of ),(
R9479 T12221 T12220 arg2Of Figure 6B,(
R9480 T12222 T12220 arg3Of ),(
R9481 T12224 T12199 arg1Of and,In
R9482 T12224 T12201 arg1Of and,","
R9483 T12224 T12223 arg1Of and,","
R9484 T12226 T12225 arg1Of expression,this
R9485 T12226 T12227 arg1Of expression,was
R9486 T12226 T12229 arg2Of expression,downregulated
R9487 T12229 T12224 arg2Of downregulated,and
R9488 T12229 T12227 arg2Of downregulated,was
R9489 T12229 T12228 arg1Of downregulated,markedly
R9490 T12234 T12232 arg1Of dose,increasing
R9491 T12234 T12233 arg1Of dose,antigen
R9492 T12234 T12235 arg1Of dose,and
R9493 T12235 T12229 arg1Of and,downregulated
R9494 T12235 T12230 arg2Of and,by
R9495 T12235 T12231 arg1Of and,both
R9496 T12235 T12237 arg1Of and,in
R9497 T12236 T12235 arg2Of coculture,and
R9498 T12238 T12237 arg2Of IL-12,in
R9499 T12238 T12239 arg1Of IL-12,(
R95 T184 T183 arg2Of IFN-γ,(
R9500 T12240 T12239 arg2Of Figure 6B,(
R9501 T12241 T12239 arg3Of ),(
R9502 T12242 T12243 arg1Of Differentiation,of
R9503 T12242 T12245 arg1Of Differentiation,under
R9504 T12242 T12249 arg1Of Differentiation,led
R9505 T12244 T12243 arg2Of T cells,of
R9506 T12248 T12245 arg2Of dose,under
R9507 T12248 T12246 arg1Of dose,low
R9508 T12248 T12247 arg1Of dose,antigen
R9509 T12249 T12250 arg1Of led,to
R9510 T12249 T12254 arg1Of led,","
R9511 T12249 T12255 arg1Of led,in
R9512 T12251 T12250 arg2Of expression,to
R9513 T12251 T12252 arg1Of expression,of
R9514 T12253 T12252 arg2Of c-maf,of
R9515 T12256 T12255 arg2Of keeping,in
R9516 T12256 T12257 arg1Of keeping,with
R9517 T12261 T12257 arg2Of profile,with
R9518 T12261 T12258 arg1Of profile,the
R9519 T12261 T12259 arg1Of profile,Th2
R9520 T12261 T12260 arg1Of profile,cell
R9521 T12261 T12262 arg1Of profile,(
R9522 T12261 T12268 arg1Of profile,","
R9523 T12261 T12269 arg1Of profile,which
R9524 T12261 T12270 arg1Of profile,was
R9525 T12261 T12273 arg2Of profile,abrogated
R9526 T12264 T12262 arg2Of et al.,(
R9527 T12264 T12263 arg1Of et al.,Ho
R9528 T12264 T12265 arg1Of et al.,","
R9529 T12266 T12265 arg2Of 1996,","
R9530 T12267 T12262 arg3Of ),(
R9531 T12272 T12271 arg1Of completely,almost
R9532 T12273 T12270 arg2Of abrogated,was
R9533 T12273 T12272 arg1Of abrogated,completely
R9534 T12276 T12273 arg1Of doses,abrogated
R9535 T12276 T12274 arg2Of doses,by
R9536 T12276 T12275 arg1Of doses,increasing
R9537 T12276 T12277 arg1Of doses,of
R9538 T12278 T12277 arg2Of antigen,of
R9539 T12278 T12279 arg1Of antigen,(
R9540 T12280 T12279 arg2Of Figure 6B,(
R9541 T12281 T12279 arg3Of ),(
R9542 T12284 T12285 arg1Of IL-12,sustained
R9543 T12285 T12282 arg1Of sustained,Interestingly
R9544 T12285 T12283 arg1Of sustained,","
R9545 T12285 T12293 arg1Of sustained,at
R9546 T12288 T12285 arg2Of expression,sustained
R9547 T12288 T12286 arg1Of expression,the
R9548 T12288 T12287 arg1Of expression,high
R9549 T12288 T12289 arg1Of expression,of
R9550 T12291 T12289 arg2Of mRNA,of
R9551 T12291 T12290 arg1Of mRNA,c-Maf
R9552 T12293 T12292 arg1Of at,even
R9553 T12297 T12293 arg2Of dose,at
R9554 T12297 T12294 arg1Of dose,the
R9555 T12297 T12295 arg1Of dose,highest
R9556 T12297 T12296 arg1Of dose,antigen
R9557 T12297 T12298 arg1Of dose,(
R9558 T12299 T12298 arg2Of Figure 6B,(
R9559 T12300 T12298 arg3Of ),(
R9560 T12304 T12303 arg1Of maintenance,IL-12
R9561 T12304 T12305 arg1Of maintenance,of
R9562 T12304 T12308 arg1Of maintenance,required
R9563 T12307 T12305 arg2Of expression,of
R9564 T12307 T12306 arg1Of expression,c-maf
R9565 T12308 T12301 arg1Of required,Moreover
R9566 T12308 T12302 arg1Of required,","
R9567 T12310 T12308 arg2Of activation,required
R9568 T12310 T12309 arg1Of activation,STAT4
R9569 T12310 T12311 arg1Of activation,(
R9570 T12312 T12311 arg2Of data,(
R9571 T12312 T12314 arg2Of data,shown
R9572 T12314 T12313 arg1Of shown,not
R9573 T12315 T12311 arg3Of ),(
R9574 T12318 T12316 arg2Of cells,In
R9575 T12318 T12317 arg1Of cells,Th17
R9576 T12319 T12320 arg1Of that,expressed
R9577 T12319 T12335 arg1Of that,were
R9578 T12319 T12336 arg1Of that,undetectable
R9579 T12320 T12316 arg1Of expressed,In
R9580 T12321 T12324 arg1Of IL-17a,as
R9581 T12324 T12320 arg2Of as,expressed
R9582 T12324 T12322 arg1Of as,as
R9583 T12324 T12323 arg1Of as,well
R9584 T12326 T12325 arg1Of mRNA,IL-10
R9585 T12326 T12327 arg1Of mRNA,(
R9586 T12326 T12330 arg1Of mRNA,","
R9587 T12328 T12327 arg2Of Figure 6C,(
R9588 T12329 T12327 arg3Of ),(
R9589 T12330 T12332 arg1Of ",",and
R9590 T12331 T12330 arg2Of T-bet,","
R9591 T12332 T12324 arg2Of and,as
R9592 T12334 T12332 arg2Of mRNA,and
R9593 T12334 T12333 arg1Of mRNA,GATA-3
R9594 T12335 T12342 arg1Of were,","
R9595 T12335 T12343 arg1Of were,whereas
R9596 T12335 T12352 arg1Of were,(
R9597 T12336 T12335 arg2Of undetectable,were
R9598 T12336 T12337 arg1Of undetectable,(
R9599 T12338 T12337 arg2Of data,(
R96 T185 T183 arg3Of ),(
R9600 T12338 T12340 arg2Of data,shown
R9601 T12340 T12339 arg1Of shown,not
R9602 T12341 T12337 arg3Of ),(
R9603 T12344 T12345 arg1Of that,of
R9604 T12344 T12347 arg1Of that,was
R9605 T12344 T12348 arg1Of that,high
R9606 T12346 T12345 arg2Of ROR-γt,of
R9607 T12347 T12343 arg2Of was,whereas
R9608 T12348 T12347 arg2Of high,was
R9609 T12348 T12349 arg1Of high,(
R9610 T12350 T12349 arg2Of Figure 6C,(
R9611 T12351 T12349 arg3Of ),(
R9612 T12354 T12352 arg2Of et al.,(
R9613 T12354 T12353 arg1Of et al.,Ivanov
R9614 T12354 T12355 arg1Of et al.,","
R9615 T12356 T12355 arg2Of 2007,","
R9616 T12357 T12352 arg3Of ),(
R9617 T12359 T12358 arg1Of cells,Th17
R9618 T12359 T12361 arg1Of cells,expressed
R9619 T12359 T12370 arg1Of cells,confirming
R9620 T12361 T12360 arg1Of expressed,also
R9621 T12361 T12369 arg1Of expressed,","
R9622 T12361 T12370 modOf expressed,confirming
R9623 T12363 T12361 arg2Of amounts,expressed
R9624 T12363 T12362 arg1Of amounts,high
R9625 T12363 T12364 arg1Of amounts,of
R9626 T12365 T12364 arg2Of c-maf,of
R9627 T12365 T12366 arg1Of c-maf,(
R9628 T12367 T12366 arg2Of Figure 6C,(
R9629 T12368 T12366 arg3Of ),(
R9630 T12370 T12373 arg1Of confirming,report
R9631 T12373 T12371 arg1Of report,a
R9632 T12373 T12372 arg1Of report,recent
R9633 T12373 T12374 arg1Of report,(
R9634 T12376 T12374 arg2Of et al.,(
R9635 T12376 T12375 arg1Of et al.,Bauquet
R9636 T12376 T12377 arg1Of et al.,","
R9637 T12378 T12377 arg2Of 2009,","
R9638 T12379 T12374 arg3Of ),(
R9639 T12380 T12381 arg1Of . c-M,af
R9640 T12380 T12383 arg2Of . c-M,ore expre
R9641 T12380 T12397 arg1Of . c-M,6B
R9642 T12380 T12399 arg1Of . c-M,6C
R9643 T12383 T12381 arg2Of ore expre,af
R9644 T12383 T12382 arg1Of ore expre,is theref
R9645 T12383 T12384 arg1Of ore expre,ss
R9646 T12383 T12396 arg1Of ore expre,es
R9647 T12388 T12384 arg2Of g T cell po,ss
R9648 T12388 T12385 arg1Of g T cell po,ed
R9649 T12388 T12386 arg1Of g T cell po,in all IL-10-exp
R9650 T12388 T12387 arg1Of g T cell po,ressin
R9651 T12388 T12389 arg2Of g T cell po,pulati
R9652 T12388 T12390 arg1Of g T cell po,o
R9653 T12392 T12393 arg1Of ed,(Fi
R9654 T12393 T12390 arg2Of (Fi,o
R9655 T12393 T12391 arg1Of (Fi,ns test
R9656 T12394 T12393 arg2Of gu,(Fi
R9657 T12395 T12390 arg3Of r,o
R9658 T12396 T12370 arg2Of es ,confirming
R9659 T12396 T12409 arg1Of es ,a
R9660 T12399 T12396 arg2Of 6C,es
R9661 T12399 T12397 arg2Of 6C,6B
R9662 T12399 T12398 arg1Of 6C,and
R9663 T12405 T12399 arg2Of ific t,6C
R9664 T12405 T12400 arg1Of ific t,) an
R9665 T12405 T12401 arg1Of ific t,d
R9666 T12405 T12402 arg1Of ific t,may
R9667 T12405 T12403 arg1Of ific t,not be just a
R9668 T12405 T12404 arg1Of ific t,Th2 cell-spec
R9669 T12405 T12406 arg1Of ific t,ra
R9670 T12408 T12406 arg2Of factor ,ra
R9671 T12408 T12407 arg1Of factor ,nscription
R9672 T12411 T12409 arg2Of origin,a
R9673 T12411 T12410 arg1Of origin,s
R9674 T12411 T12412 arg1Of origin,a
R9675 T12413 T12412 arg2Of lly ,a
R9676 T12414 T12409 arg3Of t,a
R9677 T12415 T12416 arg1Of We,showed
R9678 T12416 T12417 arg1Of showed,also
R9679 T12421 T12419 arg2Of expression,like
R9680 T12421 T12420 arg1Of expression,Il10
R9681 T12424 T12423 arg1Of expression,c-maf
R9682 T12424 T12425 arg1Of expression,was
R9683 T12424 T12426 arg2Of expression,inhibited
R9684 T12426 T12416 arg2Of inhibited,showed
R9685 T12426 T12418 arg1Of inhibited,that
R9686 T12426 T12419 arg1Of inhibited,like
R9687 T12426 T12422 arg1Of inhibited,","
R9688 T12426 T12425 arg2Of inhibited,was
R9689 T12426 T12427 arg1Of inhibited,in
R9690 T12426 T12432 arg1Of inhibited,in
R9691 T12426 T12444 arg1Of inhibited,","
R9692 T12426 T12445 arg1Of inhibited,whereas
R9693 T12428 T12429 arg1Of Th1,and
R9694 T12430 T12429 arg2Of Th17,and
R9695 T12431 T12427 arg2Of cells,in
R9696 T12431 T12428 arg1Of cells,Th1
R9697 T12431 T12430 arg1Of cells,Th17
R9698 T12434 T12432 arg2Of presence,in
R9699 T12434 T12433 arg1Of presence,the
R97 T187 T186 arg2Of reported,are
R9700 T12434 T12435 arg1Of presence,of
R9701 T12437 T12438 arg1Of MEK1,and
R9702 T12439 T12438 arg2Of MEK2,and
R9703 T12440 T12435 arg2Of inhibitor,of
R9704 T12440 T12436 arg1Of inhibitor,the
R9705 T12440 T12437 arg1Of inhibitor,MEK1
R9706 T12440 T12439 arg1Of inhibitor,MEK2
R9707 T12440 T12441 arg1Of inhibitor,(
R9708 T12442 T12441 arg2Of PD184352,(
R9709 T12443 T12441 arg3Of ),(
R9710 T12446 T12447 arg1Of T-bet,and
R9711 T12448 T12447 arg2Of RORγt,and
R9712 T12449 T12446 arg1Of expression,T-bet
R9713 T12449 T12448 arg1Of expression,RORγt
R9714 T12449 T12450 arg1Of expression,was
R9715 T12449 T12452 arg2Of expression,affected
R9716 T12452 T12445 arg2Of affected,whereas
R9717 T12452 T12450 arg2Of affected,was
R9718 T12452 T12451 arg1Of affected,hardly
R9719 T12452 T12453 arg1Of affected,(
R9720 T12454 T12453 arg2Of Figure 6D,(
R9721 T12455 T12453 arg3Of ),(
R98 T187 T188 arg1Of reported,in
R99 T190 T188 arg2Of infections,in