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PMC:1447668 JSONTXT 23 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T383 0-5 CD denotes Foxp3
T384 6-15 VB denotes Represses
T385 16-26 JJ denotes Retroviral
T386 27-40 NN denotes Transcription
T387 41-43 IN denotes by
T388 44-53 VB denotes Targeting
T389 54-58 CC denotes Both
T390 59-64 NN denotes NF-κB
T391 65-68 CC denotes and
T392 69-73 NN denotes CREB
T393 74-82 NN denotes Pathways
T394 135-143 NN denotes Forkhead
T395 144-147 NN denotes box
T396 148-149 -LRB- denotes (
T397 149-152 NN denotes Fox
T398 152-153 -RRB- denotes )
T399 153-166 JJ denotes /winged-helix
T400 167-180 NN denotes transcription
T401 181-188 NN denotes factors
T402 189-197 VB denotes regulate
T403 198-206 JJ denotes multiple
T404 207-214 NN denotes aspects
T405 215-217 IN denotes of
T406 218-224 JJ denotes immune
T407 225-239 NN denotes responsiveness
T408 240-243 CC denotes and
T409 244-249 NN denotes Foxp3
T410 250-252 VB denotes is
T411 253-263 VB denotes recognized
T412 264-266 IN denotes as
T413 267-269 DT denotes an
T414 270-279 JJ denotes essential
T415 280-290 JJ denotes functional
T416 291-297 NN denotes marker
T417 298-300 IN denotes of
T418 301-311 JJ denotes regulatory
T419 312-313 NN denotes T
T420 314-319 NN denotes cells
T421 321-327 RB denotes Herein
T422 328-330 PRP denotes we
T423 331-339 VB denotes describe
T424 340-350 JJ denotes downstream
T425 351-360 NN denotes signaling
T426 361-369 NN denotes pathways
T427 370-378 VB denotes targeted
T428 379-381 IN denotes by
T429 382-387 NN denotes Foxp3
T430 388-392 WDT denotes that
T431 393-396 MD denotes may
T432 397-407 RB denotes negatively
T433 408-414 VB denotes impact
T434 415-425 JJ denotes retroviral
T435 426-438 NN denotes pathogenesis
T436 440-454 NN denotes Overexpression
T437 455-457 IN denotes of
T438 458-463 NN denotes Foxp3
T439 464-466 IN denotes in
T440 467-470 NN denotes HEK
T441 471-475 NN denotes 293T
T442 476-479 CC denotes and
T443 480-488 VB denotes purified
T444 489-493 JJ denotes CD4+
T445 494-495 NN denotes T
T446 496-501 NN denotes cells
T447 502-510 VB denotes resulted
T448 511-513 IN denotes in
T449 514-515 DT denotes a
T450 516-530 JJ denotes dose-dependent
T451 531-534 CC denotes and
T452 535-549 JJ denotes time-dependent
T453 550-558 NN denotes decrease
T454 559-561 IN denotes in
T455 562-567 JJ denotes basal
T456 568-574 NN denotes levels
T457 575-577 IN denotes of
T458 578-585 JJ denotes nuclear
T459 586-595 NN denotes factor-κB
T460 596-597 -LRB- denotes (
T461 597-602 NN denotes NF-κB
T462 602-603 -RRB- denotes )
T463 604-614 NN denotes activation
T464 616-624 NN denotes Deletion
T465 625-627 IN denotes of
T466 628-631 DT denotes the
T467 632-649 JJ denotes carboxyl-terminal
T468 650-658 NN denotes forkhead
T469 659-660 -LRB- denotes (
T470 660-663 NN denotes FKH
T471 663-664 -RRB- denotes )
T472 665-671 NN denotes domain
T473 671-672 -COMMA- denotes ,
T474 673-681 JJ denotes critical
T475 682-685 IN denotes for
T476 686-693 JJ denotes nuclear
T477 694-706 NN denotes localization
T478 707-710 CC denotes and
T479 711-722 JJ denotes DNA-binding
T480 723-731 NN denotes activity
T481 731-732 -COMMA- denotes ,
T482 733-742 VB denotes abrogated
T483 743-746 DT denotes the
T484 747-754 NN denotes ability
T485 755-757 IN denotes of
T486 758-763 NN denotes Foxp3
T487 764-766 TO denotes to
T488 767-775 VB denotes suppress
T489 776-781 NN denotes NF-κB
T490 782-790 NN denotes activity
T491 791-793 IN denotes in
T492 794-797 NN denotes HEK
T493 798-802 NN denotes 293T
T494 803-808 NN denotes cells
T495 808-809 -COMMA- denotes ,
T496 810-813 CC denotes but
T497 814-817 RB denotes not
T498 818-820 IN denotes in
T499 821-827 NN denotes Jurkat
T500 828-830 CC denotes or
T501 831-838 JJ denotes primary
T502 839-844 JJ denotes human
T503 845-849 JJ denotes CD4+
T504 850-851 NN denotes T
T505 852-857 NN denotes cells
T506 859-861 PRP denotes We
T507 862-869 RB denotes further
T508 870-881 VB denotes demonstrate
T509 882-886 IN denotes that
T510 887-892 NN denotes Foxp3
T511 893-903 VB denotes suppressed
T512 904-907 DT denotes the
T513 908-921 NN denotes transcription
T514 922-924 IN denotes of
T515 925-928 CD denotes two
T516 929-934 JJ denotes human
T517 935-945 JJ denotes retroviral
T518 946-955 NN denotes promoters
T519 956-957 -LRB- denotes (
T520 957-962 NN denotes HIV-1
T521 963-966 CC denotes and
T522 967-972 JJ denotes human
T523 973-974 NN denotes T
T524 975-979 NN denotes cell
T525 980-992 JJ denotes lymphotropic
T526 993-998 NN denotes virus
T527 999-1003 NN denotes type
T528 1004-1005 CD denotes I
T529 1006-1007 -LRB- denotes [
T530 1007-1013 NN denotes HTLV-I
T531 1013-1014 -RRB- denotes ]
T532 1014-1015 -RRB- denotes )
T533 1016-1025 VB denotes utilizing
T534 1026-1041 JJ denotes NF-κB-dependent
T535 1042-1045 CC denotes and
T536 1046-1063 JJ denotes NF-κB-independent
T537 1064-1074 NN denotes mechanisms
T538 1076-1087 NN denotes Examination
T539 1088-1090 IN denotes of
T540 1091-1094 DT denotes the
T541 1095-1101 JJ denotes latter
T542 1102-1112 VB denotes identified
T543 1113-1116 DT denotes the
T544 1117-1132 JJ denotes cAMP-responsive
T545 1133-1140 NN denotes element
T546 1141-1148 NN denotes binding
T547 1149-1156 NN denotes protein
T548 1157-1158 -LRB- denotes (
T549 1158-1162 NN denotes CREB
T550 1162-1163 -RRB- denotes )
T551 1164-1171 NN denotes pathway
T552 1172-1174 IN denotes as
T553 1175-1176 DT denotes a
T554 1177-1183 NN denotes target
T555 1184-1186 IN denotes of
T556 1187-1192 NN denotes Foxp3
T557 1194-1201 RB denotes Finally
T558 1201-1202 -COMMA- denotes ,
T559 1203-1213 NN denotes comparison
T560 1214-1216 IN denotes of
T561 1217-1220 DT denotes the
T562 1221-1228 NN denotes percent
T563 1229-1244 JJ denotes Foxp3+CD4+CD25+
T564 1245-1246 NN denotes T
T565 1247-1252 NN denotes cells
T566 1253-1255 TO denotes to
T567 1256-1259 DT denotes the
T568 1260-1266 NN denotes HTLV-I
T569 1267-1275 JJ denotes proviral
T570 1276-1280 NN denotes load
T571 1281-1283 IN denotes in
T572 1284-1299 JJ denotes HTLV-I-infected
T573 1300-1312 JJ denotes asymptomatic
T574 1313-1321 NN denotes carriers
T575 1322-1325 CC denotes and
T576 1326-1334 NN denotes patients
T577 1335-1339 IN denotes with
T578 1340-1357 JJ denotes HTLV-I-associated
T579 1358-1377 JJ denotes myelopathy/tropical
T580 1378-1385 JJ denotes spastic
T581 1386-1397 NN denotes paraparesis
T582 1398-1407 VB denotes suggested
T583 1408-1412 IN denotes that
T584 1413-1417 JJ denotes high
T585 1418-1423 NN denotes Foxp3
T586 1424-1434 NN denotes expression
T587 1435-1437 VB denotes is
T588 1438-1448 VB denotes associated
T589 1449-1453 IN denotes with
T590 1454-1457 JJ denotes low
T591 1458-1466 JJ denotes proviral
T592 1467-1471 NN denotes load
T593 1472-1475 CC denotes and
T594 1476-1483 NN denotes absence
T595 1484-1486 IN denotes of
T596 1487-1494 NN denotes disease
T597 1496-1501 DT denotes These
T598 1502-1509 NN denotes results
T599 1510-1517 VB denotes suggest
T600 1518-1520 DT denotes an
T601 1521-1529 VB denotes expanded
T602 1530-1534 NN denotes role
T603 1535-1538 IN denotes for
T604 1539-1544 NN denotes Foxp3
T605 1545-1547 IN denotes in
T606 1548-1558 VB denotes regulating
T607 1559-1565 NN denotes NF-κB-
T608 1566-1569 CC denotes and
T609 1570-1584 JJ denotes CREB-dependent
T610 1585-1593 JJ denotes cellular
T611 1594-1597 CC denotes and
T612 1598-1603 JJ denotes viral
T613 1604-1608 NN denotes gene
T614 1609-1619 NN denotes expression
T1832 3003-3016 JJ denotes Immunological
T1833 3017-3026 NN denotes tolerance
T1834 3027-3029 TO denotes to
T1835 3030-3043 NN denotes self-antigens
T1836 3044-3046 VB denotes is
T1837 3047-3050 DT denotes the
T1838 3051-3057 NN denotes result
T1839 3058-3060 IN denotes of
T1840 3061-3064 DT denotes the
T1841 3065-3073 NN denotes deletion
T1842 3074-3076 IN denotes of
T1843 3077-3090 JJ denotes self-reactive
T1844 3091-3092 NN denotes T
T1845 3093-3104 NN denotes lymphocytes
T1846 3105-3107 IN denotes in
T1847 3108-3111 DT denotes the
T1848 3112-3118 NN denotes thymus
T1849 3119-3120 -LRB- denotes (
T1850 3120-3127 JJ denotes central
T1851 3128-3137 NN denotes tolerance
T1852 3137-3138 -RRB- denotes )
T1853 3139-3142 CC denotes and
T1854 3143-3154 NN denotes suppression
T1855 3155-3157 IN denotes of
T1856 3158-3161 DT denotes the
T1857 3162-3172 NN denotes activation
T1858 3173-3175 IN denotes of
T1859 3176-3187 RB denotes potentially
T1860 3188-3201 JJ denotes self-reactive
T1861 3202-3203 NN denotes T
T1862 3204-3215 NN denotes lymphocytes
T1863 3216-3218 IN denotes in
T1864 3219-3222 DT denotes the
T1865 3223-3232 NN denotes periphery
T1866 3233-3234 -LRB- denotes (
T1867 3234-3244 JJ denotes peripheral
T1868 3245-3254 NN denotes tolerance
T1869 3254-3255 -RRB- denotes )
T1870 3256-3257 -LRB- denotes [
T1871 3257-3258 CD denotes 1
T1872 3258-3259 -RRB- denotes ]
T1873 3261-3272 NN denotes Suppression
T1874 3273-3275 IN denotes of
T1875 3276-3286 JJ denotes pathogenic
T1876 3287-3288 NN denotes T
T1877 3289-3293 NN denotes cell
T1878 3294-3303 NN denotes responses
T1879 3304-3306 VB denotes is
T1880 3307-3315 VB denotes mediated
T1881 3316-3318 IN denotes by
T1882 3319-3328 RB denotes naturally
T1883 3329-3336 VB denotes arising
T1884 3337-3346 JJ denotes CD4+CD25+
T1885 3347-3348 NN denotes T
T1886 3349-3359 JJ denotes regulatory
T1887 3360-3365 NN denotes cells
T1888 3366-3367 -LRB- denotes (
T1889 3367-3372 NN denotes Tregs
T1890 3372-3373 -RRB- denotes )
T1891 3374-3375 -LRB- denotes [
T1892 3375-3378 CD denotes 2,3
T1893 3378-3379 -RRB- denotes ]
T1894 3381-3393 NN denotes Deficiencies
T1895 3394-3396 IN denotes in
T1896 3397-3401 NN denotes Treg
T1897 3402-3413 NN denotes development
T1898 3414-3417 CC denotes and
T1899 3418-3426 NN denotes function
T1900 3427-3431 VB denotes have
T1901 3432-3436 VB denotes been
T1902 3437-3443 VB denotes linked
T1903 3444-3446 TO denotes to
T1904 3447-3450 DT denotes the
T1905 3451-3457 JJ denotes severe
T1906 3458-3468 JJ denotes autoimmune
T1907 3469-3477 NN denotes disorder
T1908 3478-3483 VB denotes known
T1909 3484-3486 IN denotes as
T1910 3487-3493 JJ denotes immune
T1911 3494-3507 NN denotes dysregulation
T1912 3507-3508 -COMMA- denotes ,
T1913 3509-3527 NN denotes polyendocrinopathy
T1914 3527-3528 -COMMA- denotes ,
T1915 3529-3540 NN denotes enteropathy
T1916 3540-3541 -COMMA- denotes ,
T1917 3542-3550 JJ denotes X-linked
T1918 3551-3559 NN denotes syndrome
T1919 3560-3561 -LRB- denotes (
T1920 3561-3565 NN denotes IPEX
T1921 3565-3566 -RRB- denotes )
T1922 3567-3568 -LRB- denotes [
T1923 3568-3569 CD denotes 4
T1924 3569-3570 -RRB- denotes ]
T1925 3572-3574 IN denotes In
T1926 3575-3583 NN denotes addition
T1927 3583-3584 -COMMA- denotes ,
T1928 3585-3591 JJ denotes recent
T1929 3592-3599 NN denotes studies
T1930 3600-3604 VB denotes have
T1931 3605-3613 VB denotes provided
T1932 3614-3620 JJ denotes strong
T1933 3621-3629 NN denotes evidence
T1934 3630-3634 IN denotes that
T1935 3635-3648 NN denotes dysregulation
T1936 3649-3651 IN denotes of
T1937 3652-3656 NN denotes Treg
T1938 3657-3668 NN denotes development
T1939 3669-3675 CC denotes and/or
T1940 3676-3684 NN denotes function
T1941 3685-3688 MD denotes may
T1942 3689-3691 VB denotes be
T1943 3692-3693 DT denotes a
T1944 3694-3705 JJ denotes significant
T1945 3706-3712 NN denotes factor
T1946 3713-3715 IN denotes in
T1947 3716-3719 DT denotes the
T1948 3720-3732 NN denotes pathogenesis
T1949 3733-3735 IN denotes of
T1950 3736-3743 JJ denotes several
T1951 3744-3754 JJ denotes autoimmune
T1952 3755-3764 NN denotes disorders
T1953 3765-3766 -LRB- denotes (
T1954 3766-3770 FW denotes e.g.
T1955 3770-3771 -COMMA- denotes ,
T1956 3772-3780 JJ denotes multiple
T1957 3781-3790 NN denotes sclerosis
T1958 3791-3792 -LRB- denotes [
T1959 3792-3793 CD denotes 5
T1960 3793-3794 -RRB- denotes ]
T1961 3794-3795 -COMMA- denotes ,
T1962 3796-3806 NN denotes myasthenia
T1963 3807-3813 NN denotes gravis
T1964 3814-3815 -LRB- denotes [
T1965 3815-3816 CD denotes 6
T1966 3816-3817 -RRB- denotes ]
T1967 3817-3818 -COMMA- denotes ,
T1968 3819-3822 CC denotes and
T1969 3823-3827 NN denotes type
T1970 3828-3829 CD denotes 1
T1971 3830-3838 NN denotes diabetes
T1972 3839-3840 -LRB- denotes [
T1973 3840-3841 CD denotes 7
T1974 3841-3842 -RRB- denotes ]
T1975 3842-3843 -RRB- denotes )
T1976 3844-3847 CC denotes and
T1977 3848-3861 JJ denotes virus-induced
T1978 3862-3873 JJ denotes immunologic
T1979 3874-3883 NN denotes disorders
T1980 3884-3885 -LRB- denotes (
T1981 3885-3889 FW denotes e.g.
T1982 3889-3890 -COMMA- denotes ,
T1983 3891-3896 JJ denotes human
T1984 3897-3898 NN denotes T
T1985 3899-3911 JJ denotes lymphotropic
T1986 3912-3917 NN denotes virus
T1987 3918-3922 NN denotes type
T1988 3923-3924 CD denotes I
T1989 3925-3926 -LRB- denotes [
T1990 3926-3932 NN denotes HTLV-I
T1991 3932-3933 -RRB- denotes ]
T1992 3933-3944 JJ denotes -associated
T1993 3945-3964 JJ denotes myelopathy/tropical
T1994 3965-3972 JJ denotes spastic
T1995 3973-3984 NN denotes paraparesis
T1996 3985-3986 -LRB- denotes [
T1997 3986-3993 NN denotes HAM/TSP
T1998 3993-3994 -RRB- denotes ]
T1999 3994-3995 -COMMA- denotes ,
T2000 3996-3999 CC denotes and
T2001 4000-4011 JJ denotes HIV-induced
T2002 4012-4016 NNP denotes AIDS
T2003 4017-4018 -LRB- denotes [
T2004 4018-4022 CD denotes 8–10
T2005 4022-4023 -RRB- denotes ]
T2006 4023-4024 -RRB- denotes )
T2007 4026-4029 DT denotes The
T2008 4030-4043 NN denotes transcription
T2009 4044-4050 NN denotes factor
T2010 4051-4056 NN denotes Foxp3
T2011 4057-4059 VB denotes is
T2012 4060-4061 DT denotes a
T2013 4062-4071 JJ denotes 431-amino
T2014 4072-4076 NN denotes acid
T2015 4077-4078 -LRB- denotes (
T2016 4078-4084 JJ denotes 48-kDa
T2017 4084-4085 -RRB- denotes )
T2018 4086-4093 NN denotes protein
T2019 4094-4103 VB denotes expressed
T2020 4104-4106 IN denotes at
T2021 4107-4111 RB denotes very
T2022 4112-4116 JJ denotes high
T2023 4117-4123 NN denotes levels
T2024 4124-4126 IN denotes in
T2025 4127-4137 JJ denotes CD4+CD25hi
T2026 4138-4139 NN denotes T
T2027 4140-4145 NN denotes cells
T2028 4146-4149 CC denotes and
T2029 4150-4153 VB denotes has
T2030 4154-4164 RB denotes previously
T2031 4165-4169 VB denotes been
T2032 4170-4175 VB denotes shown
T2033 4176-4178 TO denotes to
T2034 4179-4181 VB denotes be
T2035 4182-4192 RB denotes absolutely
T2036 4193-4201 JJ denotes critical
T2037 4202-4205 IN denotes for
T2038 4206-4210 NN denotes Treg
T2039 4211-4222 NN denotes development
T2040 4223-4226 CC denotes and
T2041 4227-4235 NN denotes function
T2042 4236-4237 -LRB- denotes [
T2043 4237-4242 CD denotes 11–14
T2044 4242-4243 -RRB- denotes ]
T2045 4245-4250 NN denotes Foxp3
T2046 4251-4259 VB denotes contains
T2047 4260-4261 DT denotes a
T2048 4262-4274 JJ denotes proline-rich
T2049 4275-4289 JJ denotes amino-terminal
T2050 4290-4296 NN denotes domain
T2051 4297-4305 VB denotes reported
T2052 4306-4308 TO denotes to
T2053 4309-4317 VB denotes function
T2054 4318-4320 IN denotes as
T2055 4321-4322 DT denotes a
T2056 4323-4330 JJ denotes nuclear
T2057 4331-4337 NN denotes factor
T2058 4338-4340 IN denotes of
T2059 4341-4350 VB denotes activated
T2060 4351-4352 NN denotes T
T2061 4353-4358 NN denotes cells
T2062 4359-4360 -LRB- denotes (
T2063 4360-4365 NN denotes NF-AT
T2064 4365-4366 -RRB- denotes )
T2065 4367-4370 CC denotes and
T2066 4371-4378 JJ denotes nuclear
T2067 4379-4388 NN denotes factor-κB
T2068 4389-4390 -LRB- denotes (
T2069 4390-4395 NN denotes NF-κB
T2070 4395-4396 -RRB- denotes )
T2071 4397-4404 NN denotes binding
T2072 4405-4411 NN denotes domain
T2073 4411-4412 -COMMA- denotes ,
T2074 4413-4414 DT denotes a
T2075 4415-4422 JJ denotes central
T2076 4423-4429 NN denotes region
T2077 4430-4440 VB denotes containing
T2078 4441-4442 DT denotes a
T2079 4443-4447 NN denotes zinc
T2080 4448-4454 NN denotes finger
T2081 4455-4458 CC denotes and
T2082 4459-4466 NN denotes leucine
T2083 4467-4473 NN denotes zipper
T2084 4474-4485 RB denotes potentially
T2085 4486-4495 JJ denotes important
T2086 4496-4499 IN denotes for
T2087 4500-4515 JJ denotes protein-protein
T2088 4516-4528 NN denotes interactions
T2089 4528-4529 -COMMA- denotes ,
T2090 4530-4533 CC denotes and
T2091 4534-4535 DT denotes a
T2092 4536-4553 JJ denotes carboxyl-terminal
T2093 4554-4562 NN denotes forkhead
T2094 4563-4564 -LRB- denotes (
T2095 4564-4567 NN denotes FKH
T2096 4567-4568 -RRB- denotes )
T2097 4569-4575 NN denotes domain
T2098 4576-4584 VB denotes required
T2099 4585-4588 IN denotes for
T2100 4589-4596 JJ denotes nuclear
T2101 4597-4609 NN denotes localization
T2102 4610-4613 CC denotes and
T2103 4614-4625 JJ denotes DNA-binding
T2104 4626-4634 NN denotes activity
T2105 4635-4636 -LRB- denotes [
T2106 4636-4641 CD denotes 14–16
T2107 4641-4642 -RRB- denotes ]
T2108 4644-4654 JJ denotes Functional
T2109 4655-4667 NN denotes inactivation
T2110 4668-4670 IN denotes of
T2111 4671-4676 NN denotes Foxp3
T2112 4677-4679 IN denotes by
T2113 4680-4687 JJ denotes genetic
T2114 4688-4697 NN denotes mutations
T2115 4698-4707 VB denotes affecting
T2116 4708-4711 DT denotes the
T2117 4712-4717 NN denotes Foxp3
T2118 4718-4724 NN denotes coding
T2119 4725-4731 NN denotes region
T2120 4731-4732 -COMMA- denotes ,
T2121 4733-4735 IN denotes as
T2122 4736-4748 VB denotes demonstrated
T2123 4749-4751 IN denotes in
T2124 4752-4756 NN denotes IPEX
T2125 4756-4757 -COMMA- denotes ,
T2126 4758-4760 CC denotes or
T2127 4761-4771 NN denotes repression
T2128 4772-4774 IN denotes of
T2129 4775-4780 NN denotes Foxp3
T2130 4781-4791 NN denotes expression
T2131 4792-4794 IN denotes by
T2132 4795-4798 DT denotes the
T2133 4799-4813 JJ denotes HTLV-I-encoded
T2134 4814-4828 NN denotes transactivator
T2135 4829-4836 NN denotes protein
T2136 4837-4840 NN denotes Tax
T2137 4840-4841 -COMMA- denotes ,
T2138 4842-4844 IN denotes as
T2139 4845-4853 RB denotes recently
T2140 4854-4862 VB denotes reported
T2141 4863-4865 IN denotes in
T2142 4866-4874 NN denotes patients
T2143 4875-4879 IN denotes with
T2144 4880-4887 NN denotes HAM/TSP
T2145 4887-4888 -COMMA- denotes ,
T2146 4889-4896 VB denotes results
T2147 4897-4899 IN denotes in
T2148 4900-4904 NN denotes loss
T2149 4905-4907 IN denotes of
T2150 4908-4918 JJ denotes regulatory
T2151 4919-4927 NN denotes activity
T2152 4928-4930 IN denotes in
T2153 4931-4941 JJ denotes CD4+CD25hi
T2154 4942-4943 NN denotes T
T2155 4944-4949 NN denotes cells
T2156 4950-4951 -LRB- denotes [
T2157 4951-4957 CD denotes 4,8,17
T2158 4957-4958 -RRB- denotes ]
T2159 4960-4968 IN denotes Although
T2160 4969-4971 PRP denotes it
T2161 4972-4974 VB denotes is
T2162 4975-4980 JJ denotes clear
T2163 4981-4985 IN denotes that
T2164 4986-4991 NN denotes Foxp3
T2165 4992-5001 VB denotes regulates
T2166 5002-5003 NN denotes T
T2167 5004-5008 NN denotes cell
T2168 5009-5022 NN denotes proliferation
T2169 5023-5026 CC denotes and
T2170 5027-5035 NN denotes cytokine
T2171 5036-5046 NN denotes production
T2172 5046-5047 -COMMA- denotes ,
T2173 5048-5052 RB denotes very
T2174 5053-5059 JJ denotes little
T2175 5060-5062 VB denotes is
T2176 5063-5068 VB denotes known
T2177 5069-5079 VB denotes concerning
T2178 5080-5083 DT denotes the
T2179 5084-5093 JJ denotes molecular
T2180 5094-5104 NN denotes mechanisms
T2181 5105-5107 IN denotes of
T2182 5108-5113 NN denotes Foxp3
T2183 5114-5122 NN denotes function
T2184 5124-5127 DT denotes The
T2185 5128-5133 JJ denotes first
T2186 5134-5142 NN denotes evidence
T2187 5143-5145 TO denotes to
T2188 5146-5154 VB denotes indicate
T2189 5155-5158 WRB denotes how
T2190 5159-5164 NN denotes Foxp3
T2191 5165-5173 VB denotes promotes
T2192 5174-5177 DT denotes the
T2193 5178-5189 NN denotes development
T2194 5190-5193 CC denotes and
T2195 5194-5202 NN denotes function
T2196 5203-5205 IN denotes of
T2197 5206-5216 JJ denotes regulatory
T2198 5217-5218 NN denotes T
T2199 5219-5224 NN denotes cells
T2200 5225-5229 VB denotes came
T2201 5230-5234 IN denotes from
T2202 5235-5236 DT denotes a
T2203 5237-5243 NN denotes report
T2204 5244-5246 IN denotes by
T2205 5247-5254 NN denotes Ziegler
T2206 5255-5258 CC denotes and
T2207 5259-5269 NN denotes colleagues
T2208 5270-5271 -LRB- denotes [
T2209 5271-5273 CD denotes 16
T2210 5273-5274 -RRB- denotes ]
T2211 5274-5275 -COMMA- denotes ,
T2212 5276-5281 WDT denotes which
T2213 5282-5291 VB denotes suggested
T2214 5292-5296 IN denotes that
T2215 5297-5302 NN denotes Foxp3
T2216 5303-5308 MD denotes could
T2217 5309-5316 VB denotes inhibit
T2218 5317-5332 JJ denotes transcriptional
T2219 5333-5343 NN denotes activation
T2220 5344-5346 IN denotes by
T2221 5347-5357 RB denotes physically
T2222 5358-5369 VB denotes interacting
T2223 5370-5374 IN denotes with
T2224 5375-5383 NN denotes forkhead
T2225 5384-5391 NN denotes binding
T2226 5392-5397 NN denotes sites
T2227 5398-5405 JJ denotes located
T2228 5406-5417 RB denotes immediately
T2229 5418-5426 JJ denotes adjacent
T2230 5427-5429 TO denotes to
T2231 5430-5438 JJ denotes critical
T2232 5439-5449 JJ denotes cis-acting
T2233 5450-5455 NN denotes NF-AT
T2234 5456-5463 NN denotes binding
T2235 5464-5469 NN denotes sites
T2236 5470-5475 VB denotes found
T2237 5476-5478 IN denotes in
T2238 5479-5486 JJ denotes various
T2239 5487-5495 NN denotes cytokine
T2240 5496-5505 NN denotes promoters
T2241 5506-5507 -LRB- denotes (
T2242 5507-5511 FW denotes e.g.
T2243 5511-5512 -COMMA- denotes ,
T2244 5513-5517 NN denotes IL-2
T2245 5518-5526 NN denotes promoter
T2246 5526-5527 -RRB- denotes )
T2247 5529-5533 DT denotes That
T2248 5534-5539 NN denotes study
T2249 5540-5544 RB denotes also
T2250 5545-5557 VB denotes demonstrated
T2251 5558-5562 IN denotes that
T2252 5563-5568 NN denotes Foxp3
T2253 5569-5574 MD denotes could
T2254 5575-5582 VB denotes repress
T2255 5583-5593 NN denotes activation
T2256 5594-5596 IN denotes of
T2257 5597-5598 DT denotes a
T2258 5599-5608 JJ denotes synthetic
T2259 5609-5617 NN denotes reporter
T2260 5618-5624 NN denotes vector
T2261 5625-5635 VB denotes containing
T2262 5636-5638 DT denotes an
T2263 5639-5643 NN denotes SV40
T2264 5644-5652 NN denotes promoter
T2265 5653-5656 CC denotes and
T2266 5657-5662 CD denotes three
T2267 5663-5669 JJ denotes tandem
T2268 5670-5676 NN denotes copies
T2269 5677-5679 IN denotes of
T2270 5680-5681 DT denotes a
T2271 5682-5690 NN denotes forkhead
T2272 5691-5698 NN denotes binding
T2273 5699-5703 NN denotes site
T2274 5705-5710 DT denotes These
T2275 5711-5718 NN denotes results
T2276 5719-5727 VB denotes provided
T2277 5728-5738 JJ denotes additional
T2278 5739-5747 NN denotes evidence
T2279 5748-5758 VB denotes suggesting
T2280 5759-5763 IN denotes that
T2281 5764-5769 CD denotes Foxp3
T2282 5770-5785 JJ denotes transcriptional
T2283 5786-5796 NN denotes repression
T2284 5797-5800 VB denotes was
T2285 5801-5809 VB denotes mediated
T2286 5810-5812 IN denotes by
T2287 5813-5820 NN denotes binding
T2288 5821-5823 IN denotes in
T2289 5824-5825 DT denotes a
T2290 5826-5843 JJ denotes sequence-specific
T2291 5844-5850 NN denotes manner
T2292 5851-5853 TO denotes to
T2293 5854-5863 NN denotes promoters
T2294 5864-5874 VB denotes containing
T2295 5875-5883 NN denotes forkhead
T2296 5884-5891 NN denotes binding
T2297 5892-5897 NN denotes sites
T2298 5899-5900 DT denotes A
T2299 5901-5907 JJ denotes recent
T2300 5908-5913 NN denotes study
T2301 5914-5916 IN denotes by
T2302 5917-5925 NNP denotes Bettelli
T2303 5926-5929 CC denotes and
T2304 5930-5940 NN denotes colleagues
T2305 5941-5942 -LRB- denotes [
T2306 5942-5944 CD denotes 15
T2307 5944-5945 -RRB- denotes ]
T2308 5946-5953 RB denotes further
T2309 5954-5966 VB denotes demonstrated
T2310 5967-5971 IN denotes that
T2311 5972-5977 NN denotes Foxp3
T2312 5978-5983 MD denotes could
T2313 5984-5991 VB denotes inhibit
T2314 5992-5997 NN denotes NF-AT
T2315 5998-6000 RB denotes as
T2316 6001-6005 RB denotes well
T2317 6006-6008 IN denotes as
T2318 6009-6014 NN denotes NF-κB
T2319 6015-6025 NN denotes activation
T2320 6025-6026 -COMMA- denotes ,
T2321 6027-6035 IN denotes although
T2322 6036-6039 DT denotes the
T2323 6040-6049 NN denotes mechanism
T2324 6050-6052 IN denotes of
T2325 6053-6064 NN denotes suppression
T2326 6065-6068 VB denotes was
T2327 6069-6074 VB denotes shown
T2328 6075-6077 TO denotes to
T2329 6078-6085 VB denotes involve
T2330 6086-6092 JJ denotes direct
T2331 6093-6108 JJ denotes protein-protein
T2332 6109-6121 NN denotes interactions
T2333 6122-6129 IN denotes between
T2334 6130-6135 NN denotes NF-AT
T2335 6136-6138 CC denotes or
T2336 6139-6144 NN denotes NF-κB
T2337 6145-6148 CC denotes and
T2338 6149-6154 NN denotes Foxp3
T2339 6155-6161 RB denotes rather
T2340 6162-6166 IN denotes than
T2341 6167-6174 NN denotes binding
T2342 6175-6177 IN denotes of
T2343 6178-6183 NN denotes Foxp3
T2344 6184-6186 TO denotes to
T2345 6187-6195 NN denotes promoter
T2346 6196-6204 NN denotes elements
T2347 6205-6213 JJ denotes adjacent
T2348 6214-6216 TO denotes to
T2349 6217-6227 JJ denotes cis-acting
T2350 6228-6233 NN denotes NF-AT
T2351 6234-6236 CC denotes or
T2352 6237-6242 NN denotes NF-κB
T2353 6243-6248 NN denotes sites
T2354 6250-6262 RB denotes Collectively
T2355 6262-6263 -COMMA- denotes ,
T2356 6264-6269 DT denotes these
T2357 6270-6274 NN denotes data
T2358 6275-6284 VB denotes suggested
T2359 6285-6289 IN denotes that
T2360 6290-6295 NN denotes Foxp3
T2361 6296-6299 MD denotes may
T2362 6300-6308 VB denotes function
T2363 6309-6311 IN denotes as
T2364 6312-6313 DT denotes a
T2365 6314-6329 JJ denotes transcriptional
T2366 6330-6339 NN denotes repressor
T2367 6339-6340 -COMMA- denotes ,
T2368 6341-6352 RB denotes potentially
T2369 6353-6360 IN denotes through
T2370 6361-6364 DT denotes the
T2371 6365-6374 NN denotes formation
T2372 6375-6377 IN denotes of
T2373 6378-6382 CC denotes both
T2374 6383-6394 JJ denotes DNA-protein
T2375 6395-6398 CC denotes and
T2376 6399-6414 JJ denotes protein-protein
T2377 6415-6427 NN denotes interactions
T2378 6429-6431 IN denotes In
T2379 6432-6435 DT denotes the
T2380 6436-6443 JJ denotes present
T2381 6444-6449 NN denotes study
T2382 6449-6450 -COMMA- denotes ,
T2383 6451-6453 PRP denotes we
T2384 6454-6462 VB denotes expanded
T2385 6463-6467 IN denotes upon
T2386 6468-6473 DT denotes these
T2387 6474-6486 NN denotes observations
T2388 6487-6489 IN denotes by
T2389 6490-6498 VB denotes defining
T2390 6499-6509 JJ denotes additional
T2391 6510-6522 NN denotes requirements
T2392 6523-6525 IN denotes of
T2393 6526-6540 JJ denotes Foxp3-mediated
T2394 6541-6551 NN denotes repression
T2395 6552-6554 IN denotes of
T2396 6555-6560 NN denotes NF-κB
T2397 6561-6571 NN denotes activation
T2398 6571-6572 -COMMA- denotes ,
T2399 6573-6576 CC denotes and
T2400 6577-6589 VB denotes investigated
T2401 6590-6597 IN denotes whether
T2402 6598-6603 NN denotes Foxp3
T2403 6604-6609 MD denotes could
T2404 6610-6616 VB denotes target
T2405 6617-6627 JJ denotes additional
T2406 6628-6637 NN denotes signaling
T2407 6638-6646 NN denotes pathways
T2408 6647-6649 IN denotes by
T2409 6650-6659 VB denotes examining
T2410 6660-6675 JJ denotes transcriptional
T2411 6676-6686 NN denotes activation
T2412 6687-6689 IN denotes of
T2413 6690-6705 JJ denotes NF-κB-dependent
T2414 6706-6709 CC denotes and
T2415 6710-6727 JJ denotes NF-κB-independent
T2416 6728-6738 JJ denotes retroviral
T2417 6739-6748 NN denotes pathogens
T2418 6750-6753 DT denotes The
T2419 6754-6770 NN denotes characterization
T2420 6771-6773 IN denotes of
T2421 6774-6777 DT denotes the
T2422 6778-6787 JJ denotes molecular
T2423 6788-6795 NN denotes targets
T2424 6796-6798 IN denotes of
T2425 6799-6804 NN denotes Foxp3
T2426 6805-6808 CC denotes and
T2427 6809-6812 DT denotes the
T2428 6813-6822 NN denotes mechanism
T2429 6822-6823 -LRB- denotes (
T2430 6823-6824 NN denotes s
T2431 6824-6825 -RRB- denotes )
T2432 6826-6834 VB denotes utilized
T2433 6835-6837 IN denotes by
T2434 6838-6843 NN denotes Foxp3
T2435 6844-6846 TO denotes to
T2436 6847-6854 VB denotes support
T2437 6855-6859 NN denotes Treg
T2438 6860-6871 NN denotes development
T2439 6872-6875 CC denotes and
T2440 6876-6884 NN denotes function
T2441 6885-6889 MD denotes will
T2442 6890-6893 VB denotes aid
T2443 6894-6896 IN denotes in
T2444 6897-6900 PRP-DOLLAR- denotes our
T2445 6901-6914 NN denotes understanding
T2446 6915-6917 IN denotes of
T2447 6918-6921 DT denotes the
T2448 6922-6926 NN denotes role
T2449 6927-6932 VB denotes Tregs
T2450 6933-6937 NN denotes play
T2451 6938-6940 IN denotes in
T2452 6941-6944 DT denotes the
T2453 6945-6957 NN denotes pathogenesis
T2454 6958-6960 IN denotes of
T2455 6961-6966 JJ denotes human
T2456 6967-6977 JJ denotes autoimmune
T2457 6978-6985 NN denotes disease
T3430 6997-7002 CD denotes Foxp3
T3431 7003-7013 VB denotes Suppresses
T3432 7014-7019 NN denotes NF-κB
T3433 7020-7029 JJ denotes Dependent
T3434 7030-7045 JJ denotes Transcriptional
T3435 7046-7056 NN denotes Activation
T3436 7057-7059 TO denotes To
T3437 7060-7069 VB denotes ascertain
T3438 7070-7073 DT denotes the
T3439 7074-7083 JJ denotes molecular
T3440 7084-7094 NN denotes mechanisms
T3441 7095-7097 IN denotes by
T3442 7098-7103 WDT denotes which
T3443 7104-7109 NN denotes Foxp3
T3444 7110-7119 NN denotes functions
T3445 7120-7122 TO denotes to
T3446 7123-7130 VB denotes promote
T3447 7131-7134 DT denotes the
T3448 7135-7145 JJ denotes regulatory
T3449 7146-7154 NN denotes function
T3450 7155-7157 IN denotes of
T3451 7158-7168 NN denotes CD4+CD25hi
T3452 7169-7170 NN denotes T
T3453 7171-7176 NN denotes cells
T3454 7176-7177 -COMMA- denotes ,
T3455 7178-7180 PRP denotes we
T3456 7181-7186 RB denotes first
T3457 7187-7196 VB denotes confirmed
T3458 7197-7200 DT denotes the
T3459 7201-7209 NN denotes function
T3460 7210-7212 IN denotes of
T3461 7213-7218 NN denotes Foxp3
T3462 7219-7221 IN denotes as
T3463 7222-7223 DT denotes a
T3464 7224-7233 NN denotes repressor
T3465 7234-7236 IN denotes of
T3466 7237-7247 NN denotes activation
T3467 7248-7250 IN denotes of
T3468 7251-7256 NN denotes NF-κB
T3469 7256-7257 -COMMA- denotes ,
T3470 7258-7268 RB denotes previously
T3471 7269-7279 VB denotes implicated
T3472 7280-7282 IN denotes as
T3473 7283-7284 DT denotes a
T3474 7285-7291 NN denotes target
T3475 7292-7294 IN denotes of
T3476 7295-7300 JJ denotes other
T3477 7301-7322 JJ denotes forkhead/winged-helix
T3478 7323-7329 NN denotes family
T3479 7330-7343 NN denotes transcription
T3480 7344-7351 NN denotes factors
T3481 7352-7353 -LRB- denotes (
T3482 7353-7357 FW denotes e.g.
T3483 7357-7358 -COMMA- denotes ,
T3484 7359-7364 NN denotes Foxj1
T3485 7365-7368 CC denotes and
T3486 7369-7375 NN denotes Foxo3a
T3487 7375-7376 -RRB- denotes )
T3488 7377-7378 -LRB- denotes [
T3489 7378-7383 CD denotes 19,20
T3490 7383-7384 -RRB- denotes ]
T3491 7386-7388 PRP denotes We
T3492 7389-7397 VB denotes analyzed
T3493 7398-7401 DT denotes the
T3494 7402-7408 NN denotes effect
T3495 7409-7411 IN denotes of
T3496 7412-7417 NN denotes Foxp3
T3497 7418-7432 NN denotes overexpression
T3498 7433-7435 IN denotes on
T3499 7436-7441 NN denotes NF-κB
T3500 7442-7452 NN denotes activation
T3501 7453-7455 IN denotes in
T3502 7456-7459 NN denotes HEK
T3503 7460-7464 NN denotes 293T
T3504 7465-7470 NN denotes cells
T3505 7471-7473 IN denotes in
T3506 7474-7487 NN denotes dose-response
T3507 7488-7491 CC denotes and
T3508 7492-7496 NN denotes time
T3509 7497-7503 NN denotes course
T3510 7504-7512 NN denotes analyses
T3511 7514-7526 NN denotes Transfection
T3512 7527-7529 IN denotes of
T3513 7530-7533 NN denotes HEK
T3514 7534-7538 NN denotes 293T
T3515 7539-7544 NN denotes cells
T3516 7545-7549 IN denotes with
T3517 7550-7552 DT denotes an
T3518 7553-7558 NN denotes NF-κB
T3519 7559-7569 NN denotes luciferase
T3520 7570-7578 NN denotes reporter
T3521 7579-7585 NN denotes vector
T3522 7586-7588 IN denotes in
T3523 7589-7592 DT denotes the
T3524 7593-7601 NN denotes presence
T3525 7602-7604 CC denotes or
T3526 7605-7612 NN denotes absence
T3527 7613-7615 IN denotes of
T3528 7616-7626 VB denotes increasing
T3529 7627-7641 NN denotes concentrations
T3530 7642-7644 IN denotes of
T3531 7645-7646 DT denotes a
T3532 7647-7652 NN denotes Foxp3
T3533 7653-7663 NN denotes expression
T3534 7664-7670 NN denotes vector
T3535 7671-7673 CC denotes or
T3536 7674-7675 DT denotes a
T3537 7676-7683 NN denotes control
T3538 7684-7690 NN denotes vector
T3539 7691-7692 -LRB- denotes (
T3540 7692-7700 VB denotes enhanced
T3541 7701-7706 JJ denotes green
T3542 7707-7718 JJ denotes fluorescent
T3543 7719-7726 NN denotes protein
T3544 7727-7728 -LRB- denotes [
T3545 7728-7732 NN denotes EGFP
T3546 7732-7733 -RRB- denotes ]
T3547 7733-7734 -RRB- denotes )
T3548 7735-7738 VB denotes was
T3549 7739-7748 VB denotes performed
T3550 7748-7749 -COMMA- denotes ,
T3551 7750-7753 CC denotes and
T3552 7754-7759 NN denotes cells
T3553 7760-7764 VB denotes were
T3554 7765-7774 VB denotes harvested
T3555 7775-7780 IN denotes after
T3556 7781-7783 CD denotes 24
T3557 7784-7785 NN denotes h
T3558 7786-7788 TO denotes to
T3559 7789-7794 VB denotes assay
T3560 7795-7798 IN denotes for
T3561 7799-7809 NN denotes luciferase
T3562 7810-7818 NN denotes activity
T3563 7819-7822 CC denotes and
T3564 7823-7828 NN denotes Foxp3
T3565 7829-7833 NN denotes mRNA
T3566 7834-7844 NN denotes expression
T3567 7846-7853 NN denotes Results
T3568 7854-7863 VB denotes indicated
T3569 7864-7868 IN denotes that
T3570 7869-7871 IN denotes as
T3571 7872-7875 DT denotes the
T3572 7876-7889 NN denotes concentration
T3573 7890-7892 IN denotes of
T3574 7893-7898 NN denotes Foxp3
T3575 7899-7910 VB denotes transfected
T3576 7911-7915 IN denotes into
T3577 7916-7921 NN denotes cells
T3578 7922-7931 VB denotes increases
T3579 7932-7933 -LRB- denotes (
T3580 7933-7937 IN denotes from
T3581 7938-7940 CD denotes 50
T3582 7941-7943 TO denotes to
T3583 7944-7949 CD denotes 2,400
T3584 7950-7952 NN denotes ng
T3585 7952-7953 -RRB- denotes )
T3586 7953-7954 -COMMA- denotes ,
T3587 7955-7958 DT denotes the
T3588 7959-7964 NN denotes level
T3589 7965-7967 IN denotes of
T3590 7968-7973 NN denotes NF-κB
T3591 7974-7984 NN denotes activation
T3592 7985-7994 VB denotes decreases
T3593 7995-8009 RB denotes proportionally
T3594 8010-8011 -LRB- denotes (
T3595 8011-8017 NN denotes Figure
T3596 8018-8020 NN denotes 1A
T3597 8020-8021 -RRB- denotes )
T3598 8023-8028 NN denotes Foxp3
T3599 8029-8033 NN denotes mRNA
T3600 8034-8037 VB denotes was
T3601 8038-8042 RB denotes also
T3602 8043-8050 VB denotes assayed
T3603 8051-8053 TO denotes to
T3604 8054-8061 VB denotes monitor
T3605 8062-8070 NN denotes activity
T3606 8071-8073 IN denotes of
T3607 8074-8077 DT denotes the
T3608 8078-8083 NN denotes Foxp3
T3609 8084-8094 NN denotes expression
T3610 8095-8101 NN denotes vector
T3611 8102-8103 -LRB- denotes (
T3612 8103-8109 NN denotes Figure
T3613 8110-8112 NN denotes 1B
T3614 8112-8113 -RRB- denotes )
T3615 8115-8120 IN denotes Since
T3616 8121-8126 NN denotes NF-κB
T3617 8127-8137 NN denotes activation
T3618 8138-8141 VB denotes was
T3619 8142-8151 RB denotes partially
T3620 8152-8160 VB denotes affected
T3621 8161-8163 IN denotes by
T3622 8164-8176 NN denotes transfection
T3623 8177-8179 IN denotes of
T3624 8180-8184 JJ denotes high
T3625 8185-8199 NN denotes concentrations
T3626 8200-8202 IN denotes of
T3627 8203-8206 DT denotes the
T3628 8207-8214 NN denotes control
T3629 8215-8221 NN denotes vector
T3630 8221-8222 -COMMA- denotes ,
T3631 8223-8225 PRP denotes we
T3632 8226-8236 VB denotes determined
T3633 8237-8240 DT denotes the
T3634 8241-8245 JJ denotes fold
T3635 8246-8256 NN denotes inhibition
T3636 8257-8259 IN denotes of
T3637 8260-8265 NN denotes NF-κB
T3638 8266-8276 NN denotes activation
T3639 8277-8279 IN denotes by
T3640 8280-8285 NN denotes Foxp3
T3641 8286-8294 VB denotes compared
T3642 8295-8297 TO denotes to
T3643 8298-8301 DT denotes the
T3644 8302-8309 NN denotes control
T3645 8310-8316 NN denotes vector
T3646 8317-8319 IN denotes at
T3647 8320-8324 DT denotes each
T3648 8325-8338 NN denotes concentration
T3649 8339-8340 -LRB- denotes (
T3650 8340-8346 NN denotes Figure
T3651 8347-8349 NN denotes 1A
T3652 8349-8350 -RRB- denotes )
T3653 8352-8356 JJ denotes Fold
T3654 8357-8367 NN denotes inhibition
T3655 8368-8370 IN denotes of
T3656 8371-8376 NN denotes NF-κB
T3657 8377-8387 NN denotes activation
T3658 8388-8391 VB denotes was
T3659 8392-8400 RB denotes directly
T3660 8401-8413 JJ denotes proportional
T3661 8414-8416 TO denotes to
T3662 8417-8420 DT denotes the
T3663 8421-8426 NN denotes level
T3664 8427-8429 IN denotes of
T3665 8430-8435 NN denotes Foxp3
T3666 8436-8440 NN denotes mRNA
T3667 8441-8451 NN denotes expression
T3668 8452-8460 VB denotes detected
T3669 8461-8463 IN denotes by
T3670 8464-8473 JJ denotes real-time
T3671 8474-8480 NN denotes RT-PCR
T3672 8482-8484 TO denotes To
T3673 8485-8494 VB denotes determine
T3674 8495-8498 DT denotes the
T3675 8499-8504 NN denotes level
T3676 8505-8507 IN denotes of
T3677 8508-8522 JJ denotes Foxp3-mediated
T3678 8523-8534 NN denotes suppression
T3679 8535-8537 IN denotes of
T3680 8538-8543 NN denotes NF-κB
T3681 8544-8554 NN denotes activation
T3682 8555-8559 IN denotes over
T3683 8560-8564 NN denotes time
T3684 8564-8565 -COMMA- denotes ,
T3685 8566-8569 NN denotes HEK
T3686 8570-8574 NN denotes 293T
T3687 8575-8580 NN denotes cells
T3688 8581-8585 VB denotes were
T3689 8586-8597 VB denotes transfected
T3690 8598-8602 IN denotes with
T3691 8603-8605 DT denotes an
T3692 8606-8611 NN denotes NF-κB
T3693 8612-8622 NN denotes luciferase
T3694 8623-8631 NN denotes reporter
T3695 8632-8638 NN denotes vector
T3696 8639-8642 CC denotes and
T3697 8643-8645 DT denotes an
T3698 8646-8656 NN denotes expression
T3699 8657-8663 NN denotes vector
T3700 8664-8672 VB denotes encoding
T3701 8673-8678 NN denotes Foxp3
T3702 8679-8681 CC denotes or
T3703 8682-8686 NN denotes EGFP
T3704 8687-8688 -LRB- denotes (
T3705 8688-8695 NN denotes control
T3706 8696-8702 NN denotes vector
T3707 8702-8703 -RRB- denotes )
T3708 8704-8707 CC denotes and
T3709 8708-8717 VB denotes harvested
T3710 8718-8722 IN denotes over
T3711 8723-8724 CD denotes 4
T3712 8725-8726 NN denotes d
T3713 8728-8730 IN denotes As
T3714 8731-8736 VB denotes shown
T3715 8737-8739 IN denotes in
T3716 8740-8746 NN denotes Figure
T3717 8747-8749 NN denotes 1C
T3718 8749-8750 -COMMA- denotes ,
T3719 8751-8756 NN denotes NF-κB
T3720 8757-8767 NN denotes activation
T3721 8768-8771 VB denotes was
T3722 8772-8782 VB denotes suppressed
T3723 8783-8785 IN denotes by
T3724 8786-8800 NN denotes overexpression
T3725 8801-8803 IN denotes of
T3726 8804-8809 NN denotes Foxp3
T3727 8810-8812 IN denotes at
T3728 8813-8816 DT denotes all
T3729 8817-8821 NN denotes time
T3730 8822-8828 NN denotes points
T3731 8830-8839 VB denotes Extending
T3732 8840-8845 DT denotes these
T3733 8846-8853 NN denotes results
T3734 8854-8858 IN denotes from
T3735 8859-8870 VB denotes established
T3736 8870-8871 -COMMA- denotes ,
T3737 8872-8874 FW denotes in
T3738 8875-8880 FW denotes vitro
T3739 8881-8884 NN denotes HEK
T3740 8885-8889 NN denotes cell
T3741 8890-8895 NN denotes lines
T3742 8896-8898 TO denotes to
T3743 8899-8906 JJ denotes primary
T3744 8907-8912 JJ denotes human
T3745 8913-8924 NN denotes lymphocytes
T3746 8924-8925 -COMMA- denotes ,
T3747 8926-8940 NN denotes overexpression
T3748 8941-8943 IN denotes of
T3749 8944-8949 NN denotes Foxp3
T3750 8950-8952 IN denotes in
T3751 8953-8961 VB denotes purified
T3752 8962-8966 JJ denotes CD4+
T3753 8967-8968 NN denotes T
T3754 8969-8974 NN denotes cells
T3755 8975-8979 IN denotes from
T3756 8980-8985 CD denotes three
T3757 8986-8993 JJ denotes healthy
T3758 8994-9000 NN denotes donors
T3759 9001-9005 RB denotes also
T3760 9006-9020 VB denotes down-regulated
T3761 9021-9024 DT denotes the
T3762 9025-9037 JJ denotes steady-state
T3763 9038-9043 NN denotes level
T3764 9044-9046 IN denotes of
T3765 9047-9052 NN denotes NF-κB
T3766 9053-9063 NN denotes activation
T3767 9064-9065 -LRB- denotes (
T3768 9065-9071 NN denotes Figure
T3769 9072-9074 NN denotes 1D
T3770 9074-9075 -RRB- denotes )
T3771 9077-9082 DT denotes These
T3772 9083-9090 NN denotes results
T3773 9091-9103 VB denotes recapitulate
T3774 9104-9109 DT denotes those
T3775 9110-9114 IN denotes from
T3776 9115-9123 NNP denotes Bettelli
T3777 9124-9127 CC denotes and
T3778 9128-9138 NN denotes colleagues
T3779 9139-9140 -LRB- denotes [
T3780 9140-9142 CD denotes 15
T3781 9142-9143 -RRB- denotes ]
T3782 9144-9157 VB denotes demonstrating
T3783 9158-9162 IN denotes that
T3784 9163-9168 CD denotes Foxp3
T3785 9169-9178 NN denotes functions
T3786 9178-9179 -COMMA- denotes ,
T3787 9180-9182 IN denotes in
T3788 9183-9187 NN denotes part
T3789 9187-9188 -COMMA- denotes ,
T3790 9189-9191 TO denotes to
T3791 9192-9197 VB denotes block
T3792 9198-9213 JJ denotes NF-κB-dependent
T3793 9214-9227 NN denotes transcription
T3794 9228-9230 IN denotes in
T3795 9231-9236 JJ denotes human
T3796 9237-9241 NN denotes cell
T3797 9242-9247 NN denotes lines
T3798 9248-9250 RB denotes as
T3799 9251-9255 RB denotes well
T3800 9256-9258 IN denotes as
T3801 9259-9261 IN denotes in
T3802 9262-9269 JJ denotes primary
T3803 9270-9275 JJ denotes human
T3804 9276-9280 JJ denotes CD4+
T3805 9281-9282 NN denotes T
T3806 9283-9288 NN denotes cells
T4732 10544-10547 DT denotes The
T4733 10548-10565 JJ denotes Carboxyl-Terminal
T4734 10566-10569 NN denotes FKH
T4735 10570-10576 NN denotes Domain
T4736 10577-10579 VB denotes Is
T4737 10580-10583 RB denotes Not
T4738 10584-10592 VB denotes Required
T4739 10593-10596 IN denotes for
T4740 10597-10608 NN denotes Suppression
T4741 10609-10611 IN denotes of
T4742 10612-10617 NN denotes NF-κB
T4743 10618-10628 NN denotes Activation
T4744 10629-10631 IN denotes in
T4745 10632-10633 NN denotes T
T4746 10634-10639 NN denotes Cells
T4747 10640-10642 TO denotes To
T4748 10643-10649 VB denotes define
T4749 10650-10653 DT denotes the
T4750 10654-10666 NN denotes requirements
T4751 10667-10669 IN denotes of
T4752 10670-10675 NN denotes Foxp3
T4753 10676-10680 IN denotes with
T4754 10681-10688 NN denotes respect
T4755 10689-10691 TO denotes to
T4756 10692-10702 NN denotes inhibition
T4757 10703-10705 IN denotes of
T4758 10706-10721 JJ denotes NF-κB-dependent
T4759 10722-10735 NN denotes transcription
T4760 10735-10736 -COMMA- denotes ,
T4761 10737-10739 PRP denotes we
T4762 10740-10748 VB denotes utilized
T4763 10749-10750 DT denotes a
T4764 10751-10757 NN denotes mutant
T4765 10758-10760 IN denotes of
T4766 10761-10766 NN denotes Foxp3
T4767 10767-10774 VB denotes lacking
T4768 10775-10778 DT denotes the
T4769 10779-10782 NN denotes FKH
T4770 10783-10789 NN denotes domain
T4771 10790-10791 -LRB- denotes (
T4772 10791-10797 NN denotes Figure
T4773 10798-10800 NN denotes 2A
T4774 10800-10801 -RRB- denotes )
T4775 10802-10803 -LRB- denotes [
T4776 10803-10805 CD denotes 16
T4777 10805-10806 -RRB- denotes ]
T4778 10806-10807 -COMMA- denotes ,
T4779 10808-10815 JJ denotes similar
T4780 10816-10818 TO denotes to
T4781 10819-10822 DT denotes the
T4782 10823-10829 JJ denotes scurfy
T4783 10830-10836 JJ denotes mutant
T4784 10837-10842 NN denotes Foxp3
T4785 10843-10845 IN denotes of
T4786 10846-10850 NN denotes mice
T4787 10850-10851 -COMMA- denotes ,
T4788 10852-10855 CC denotes and
T4789 10856-10857 DT denotes a
T4790 10858-10864 JJ denotes mutant
T4791 10865-10870 NN denotes Foxp3
T4792 10871-10878 NN denotes protein
T4793 10879-10883 IN denotes from
T4794 10884-10885 DT denotes a
T4795 10886-10893 NN denotes patient
T4796 10894-10898 IN denotes with
T4797 10899-10903 NN denotes IPEX
T4798 10904-10905 -LRB- denotes [
T4799 10905-10915 CD denotes 4,11,14,17
T4800 10915-10916 -RRB- denotes ]
T4801 10918-10924 IN denotes Unlike
T4802 10925-10936 JJ denotes full-length
T4803 10937-10942 NN denotes Foxp3
T4804 10942-10943 -COMMA- denotes ,
T4805 10944-10949 WDT denotes which
T4806 10950-10959 VB denotes localizes
T4807 10960-10966 RB denotes almost
T4808 10967-10978 RB denotes exclusively
T4809 10979-10981 TO denotes to
T4810 10982-10985 DT denotes the
T4811 10986-10993 NN denotes nucleus
T4812 10994-10997 CC denotes and
T4813 10998-11001 MD denotes can
T4814 11002-11006 VB denotes bind
T4815 11007-11009 IN denotes in
T4816 11010-11011 DT denotes a
T4817 11012-11029 JJ denotes sequence-specific
T4818 11030-11036 NN denotes manner
T4819 11037-11039 TO denotes to
T4820 11040-11048 VB denotes forkhead
T4821 11049-11056 VB denotes binding
T4822 11057-11062 NN denotes sites
T4823 11062-11063 -COMMA- denotes ,
T4824 11064-11067 DT denotes the
T4825 11068-11072 NN denotes ΔFKH
T4826 11073-11079 NN denotes mutant
T4827 11080-11085 VB denotes fails
T4828 11086-11088 TO denotes to
T4829 11089-11097 VB denotes localize
T4830 11098-11100 TO denotes to
T4831 11101-11104 DT denotes the
T4832 11105-11112 NN denotes nucleus
T4833 11113-11116 CC denotes and
T4834 11117-11121 RB denotes thus
T4835 11122-11125 MD denotes can
T4836 11125-11128 RB denotes not
T4837 11129-11137 VB denotes interact
T4838 11138-11142 IN denotes with
T4839 11143-11151 NN denotes promoter
T4840 11152-11160 NN denotes elements
T4841 11161-11163 CC denotes or
T4842 11164-11171 JJ denotes nuclear
T4843 11172-11180 NN denotes proteins
T4844 11181-11182 -LRB- denotes [
T4845 11182-11184 CD denotes 16
T4846 11184-11185 -RRB- denotes ]
T4847 11187-11196 RB denotes Therefore
T4848 11196-11197 -COMMA- denotes ,
T4849 11198-11200 PRP denotes we
T4850 11201-11209 VB denotes utilized
T4851 11210-11213 DT denotes the
T4852 11214-11218 NN denotes ΔFKH
T4853 11219-11225 NN denotes mutant
T4854 11226-11228 TO denotes to
T4855 11229-11238 VB denotes determine
T4856 11239-11246 IN denotes whether
T4857 11247-11254 JJ denotes nuclear
T4858 11255-11267 NN denotes localization
T4859 11268-11269 -LRB- denotes (
T4860 11269-11271 CC denotes or
T4861 11272-11277 JJ denotes other
T4862 11278-11286 NN denotes function
T4863 11287-11297 VB denotes associated
T4864 11298-11302 IN denotes with
T4865 11303-11306 DT denotes the
T4866 11307-11310 NN denotes FKH
T4867 11311-11317 NN denotes domain
T4868 11317-11318 -RRB- denotes )
T4869 11319-11321 IN denotes of
T4870 11322-11327 NN denotes Foxp3
T4871 11328-11331 VB denotes was
T4872 11332-11333 DT denotes a
T4873 11334-11346 NN denotes prerequisite
T4874 11347-11350 IN denotes for
T4875 11351-11361 NN denotes inhibition
T4876 11362-11364 IN denotes of
T4877 11365-11370 NN denotes NF-κB
T4878 11371-11381 NN denotes activation
T4879 11383-11391 IN denotes Although
T4880 11392-11397 CD denotes Foxp3
T4881 11398-11409 NN denotes interaction
T4882 11410-11414 IN denotes with
T4883 11415-11420 NN denotes NF-κB
T4884 11421-11431 RB denotes presumably
T4885 11432-11437 VB denotes takes
T4886 11438-11443 NN denotes place
T4887 11444-11446 IN denotes in
T4888 11447-11450 DT denotes the
T4889 11451-11458 NN denotes nucleus
T4890 11458-11459 -COMMA- denotes ,
T4891 11460-11462 PRP denotes it
T4892 11463-11466 MD denotes may
T4893 11467-11471 RB denotes also
T4894 11472-11474 VB denotes be
T4895 11475-11483 JJ denotes possible
T4896 11484-11487 IN denotes for
T4897 11488-11489 DT denotes a
T4898 11490-11501 JJ denotes cytoplasmic
T4899 11502-11507 NN denotes Foxp3
T4900 11508-11515 NN denotes protein
T4901 11516-11518 TO denotes to
T4902 11519-11523 VB denotes bind
T4903 11524-11526 TO denotes to
T4904 11527-11532 NN denotes NF-κB
T4905 11533-11535 IN denotes in
T4906 11536-11539 DT denotes the
T4907 11540-11549 NN denotes cytoplasm
T4908 11550-11553 CC denotes and
T4909 11554-11561 VB denotes prevent
T4910 11562-11574 NN denotes localization
T4911 11575-11577 TO denotes to
T4912 11578-11581 DT denotes the
T4913 11582-11589 NN denotes nucleus
T4914 11590-11599 VB denotes following
T4915 11600-11602 DT denotes an
T4916 11603-11613 NN denotes activation
T4917 11614-11622 NN denotes stimulus
T4918 11624-11638 NN denotes Overexpression
T4919 11639-11641 IN denotes of
T4920 11642-11653 JJ denotes full-length
T4921 11654-11659 NN denotes Foxp3
T4922 11659-11660 -COMMA- denotes ,
T4923 11661-11664 CC denotes but
T4924 11665-11668 RB denotes not
T4925 11669-11671 IN denotes of
T4926 11672-11676 NN denotes ΔFKH
T4927 11676-11677 -COMMA- denotes ,
T4928 11678-11681 VB denotes was
T4929 11682-11686 JJ denotes able
T4930 11687-11689 TO denotes to
T4931 11690-11698 VB denotes suppress
T4932 11699-11709 NN denotes activation
T4933 11710-11712 IN denotes of
T4934 11713-11714 DT denotes a
T4935 11715-11728 VB denotes cotransfected
T4936 11729-11734 NN denotes NF-κB
T4937 11735-11743 NN denotes reporter
T4938 11744-11750 NN denotes vector
T4939 11751-11753 IN denotes in
T4940 11754-11757 NN denotes HEK
T4941 11758-11762 NN denotes 293T
T4942 11763-11768 NN denotes cells
T4943 11769-11770 -LRB- denotes (
T4944 11770-11776 NN denotes Figure
T4945 11777-11779 NN denotes 2B
T4946 11779-11780 -RRB- denotes )
T4947 11782-11786 CC denotes Both
T4948 11787-11792 NN denotes Foxp3
T4949 11793-11796 CC denotes and
T4950 11797-11801 NN denotes ΔFKH
T4951 11802-11806 VB denotes were
T4952 11807-11816 VB denotes expressed
T4953 11817-11819 IN denotes at
T4954 11820-11824 RB denotes very
T4955 11825-11829 JJ denotes high
T4956 11830-11836 NN denotes levels
T4957 11837-11846 VB denotes following
T4958 11847-11859 NN denotes transfection
T4959 11860-11862 IN denotes as
T4960 11863-11871 VB denotes detected
T4961 11872-11874 IN denotes by
T4962 11875-11884 JJ denotes real-time
T4963 11885-11891 NN denotes RT-PCR
T4964 11892-11893 -LRB- denotes (
T4965 11893-11904 JJ denotes unpublished
T4966 11905-11909 NN denotes data
T4967 11909-11910 -RRB- denotes )
T4968 11912-11917 DT denotes These
T4969 11918-11922 NN denotes data
T4970 11923-11929 VB denotes appear
T4971 11930-11932 TO denotes to
T4972 11933-11940 VB denotes suggest
T4973 11941-11945 IN denotes that
T4974 11946-11949 DT denotes the
T4975 11950-11967 JJ denotes carboxyl-terminal
T4976 11968-11971 NN denotes FKH
T4977 11972-11978 NN denotes domain
T4978 11979-11981 VB denotes is
T4979 11982-11992 RB denotes critically
T4980 11993-12002 JJ denotes important
T4981 12003-12006 IN denotes for
T4982 12007-12012 CD denotes Foxp3
T4983 12013-12015 TO denotes to
T4984 12016-12029 VB denotes down-regulate
T4985 12030-12045 JJ denotes NF-κB-dependent
T4986 12046-12059 NN denotes transcription
T4987 12061-12068 RB denotes However
T4988 12068-12069 -COMMA- denotes ,
T4989 12070-12075 NN denotes NF-κB
T4990 12076-12086 NN denotes activation
T4991 12087-12090 VB denotes was
T4992 12091-12098 VB denotes blocked
T4993 12099-12101 TO denotes to
T4994 12102-12103 DT denotes a
T4995 12104-12111 JJ denotes similar
T4996 12112-12118 NN denotes extent
T4997 12119-12121 IN denotes by
T4998 12122-12126 CC denotes both
T4999 12127-12138 JJ denotes full-length
T5000 12139-12144 NN denotes Foxp3
T5001 12145-12148 CC denotes and
T5002 12149-12153 NN denotes ΔFKH
T5003 12154-12156 IN denotes in
T5004 12157-12163 NN denotes Jurkat
T5005 12164-12165 NN denotes T
T5006 12166-12171 NN denotes cells
T5007 12172-12173 -LRB- denotes (
T5008 12173-12179 NN denotes Figure
T5009 12180-12182 NN denotes 2C
T5010 12182-12183 -RRB- denotes )
T5011 12184-12187 CC denotes and
T5012 12188-12195 JJ denotes primary
T5013 12196-12201 JJ denotes human
T5014 12202-12206 JJ denotes CD4+
T5015 12207-12208 NN denotes T
T5016 12209-12214 NN denotes cells
T5017 12215-12216 -LRB- denotes (
T5018 12216-12222 NN denotes Figure
T5019 12223-12225 NN denotes 2D
T5020 12225-12226 -RRB- denotes )
T5021 12228-12235 NN denotes Western
T5022 12236-12240 NN denotes blot
T5023 12241-12249 NN denotes analysis
T5024 12250-12252 IN denotes of
T5025 12253-12258 NN denotes NF-κB
T5026 12259-12262 NN denotes p65
T5027 12263-12273 NN denotes expression
T5028 12274-12286 VB denotes demonstrated
T5029 12287-12291 IN denotes that
T5030 12292-12297 NN denotes Foxp3
T5031 12298-12301 CC denotes and
T5032 12302-12306 NN denotes ΔFKH
T5033 12307-12311 VB denotes does
T5034 12312-12315 RB denotes not
T5035 12316-12321 VB denotes block
T5036 12322-12327 NN denotes NF-κB
T5037 12328-12338 NN denotes activation
T5038 12339-12341 IN denotes at
T5039 12342-12345 DT denotes the
T5040 12346-12351 NN denotes level
T5041 12352-12354 IN denotes of
T5042 12355-12358 NN denotes p65
T5043 12359-12366 NN denotes protein
T5044 12367-12377 NN denotes expression
T5045 12378-12379 -LRB- denotes (
T5046 12379-12385 NN denotes Figure
T5047 12386-12388 NN denotes 2E
T5048 12388-12389 -RRB- denotes )
T5049 12391-12396 DT denotes These
T5050 12397-12404 NN denotes results
T5051 12405-12408 VB denotes are
T5052 12409-12413 RB denotes very
T5053 12414-12425 JJ denotes interesting
T5054 12426-12430 IN denotes with
T5055 12431-12438 NN denotes respect
T5056 12439-12441 TO denotes to
T5057 12442-12447 NN denotes Foxp3
T5058 12448-12456 NN denotes function
T5059 12456-12457 -COMMA- denotes ,
T5060 12458-12465 IN denotes because
T5061 12466-12470 PRP denotes they
T5062 12471-12478 VB denotes suggest
T5063 12479-12483 IN denotes that
T5064 12484-12487 DT denotes the
T5065 12488-12505 JJ denotes carboxyl-terminal
T5066 12506-12509 NN denotes FKH
T5067 12510-12516 NN denotes domain
T5068 12516-12517 -COMMA- denotes ,
T5069 12518-12521 CC denotes and
T5070 12522-12530 RB denotes possibly
T5071 12531-12538 JJ denotes nuclear
T5072 12539-12551 NN denotes localization
T5073 12551-12552 -COMMA- denotes ,
T5074 12553-12556 VB denotes are
T5075 12557-12568 JJ denotes dispensable
T5076 12569-12572 IN denotes for
T5077 12573-12578 NN denotes Foxp3
T5078 12579-12587 NN denotes function
T5079 12588-12590 IN denotes in
T5080 12591-12592 NN denotes T
T5081 12593-12597 NN denotes cell
T5082 12598-12609 NN denotes populations
T5083 12611-12622 JJ denotes Alternative
T5084 12623-12638 NN denotes interpretations
T5085 12639-12642 MD denotes may
T5086 12643-12650 VB denotes include
T5087 12651-12654 DT denotes the
T5088 12655-12666 NN denotes possibility
T5089 12667-12671 IN denotes that
T5090 12672-12675 DT denotes the
T5091 12676-12688 NN denotes localization
T5092 12689-12691 IN denotes of
T5093 12692-12696 NN denotes ΔFKH
T5094 12697-12703 VB denotes differ
T5095 12704-12711 IN denotes between
T5096 12712-12722 JJ denotes epithelial
T5097 12723-12728 NN denotes cells
T5098 12729-12732 CC denotes and
T5099 12733-12734 NN denotes T
T5100 12735-12740 NN denotes cells
T5101 12742-12744 IN denotes In
T5102 12745-12751 DT denotes either
T5103 12752-12756 NN denotes case
T5104 12756-12757 -COMMA- denotes ,
T5105 12758-12763 DT denotes these
T5106 12764-12771 NN denotes results
T5107 12772-12779 VB denotes suggest
T5108 12780-12781 DT denotes a
T5109 12782-12786 NN denotes cell
T5110 12787-12800 JJ denotes type-specific
T5111 12801-12810 NN denotes mechanism
T5112 12811-12813 IN denotes of
T5113 12814-12820 NN denotes action
T5114 12821-12824 IN denotes for
T5115 12825-12829 DT denotes this
T5116 12830-12835 NN denotes Foxp3
T5117 12836-12842 NN denotes mutant
T6003 14569-14574 CD denotes Foxp3
T6004 14575-14585 VB denotes Suppresses
T6005 14586-14591 NN denotes HIV-1
T6006 14592-14596 NN denotes Gene
T6007 14597-14607 NN denotes Expression
T6008 14608-14610 IN denotes in
T6009 14611-14615 NNP denotes Part
T6010 14616-14623 IN denotes through
T6011 14624-14632 VB denotes Blocking
T6012 14633-14643 NN denotes Activation
T6013 14644-14646 IN denotes of
T6014 14647-14652 NN denotes NF-κB
T6015 14653-14655 IN denotes If
T6016 14656-14661 NN denotes Foxp3
T6017 14662-14671 VB denotes functions
T6018 14672-14674 IN denotes as
T6019 14675-14676 DT denotes a
T6020 14677-14686 NN denotes repressor
T6021 14687-14689 IN denotes of
T6022 14690-14705 JJ denotes NF-κB-dependent
T6023 14706-14710 NN denotes gene
T6024 14711-14721 NN denotes expression
T6025 14721-14722 -COMMA- denotes ,
T6026 14723-14727 RB denotes then
T6027 14728-14730 PRP denotes we
T6028 14731-14743 VB denotes hypothesized
T6029 14744-14748 IN denotes that
T6030 14749-14754 NN denotes Foxp3
T6031 14755-14769 NN denotes overexpression
T6032 14770-14775 MD denotes could
T6033 14776-14787 RB denotes selectively
T6034 14788-14801 VB denotes down-regulate
T6035 14802-14815 NN denotes transcription
T6036 14816-14820 IN denotes from
T6037 14821-14830 NN denotes promoters
T6038 14831-14841 RB denotes previously
T6039 14842-14847 VB denotes shown
T6040 14848-14850 TO denotes to
T6041 14851-14853 VB denotes be
T6042 14854-14864 JJ denotes responsive
T6043 14865-14867 TO denotes to
T6044 14868-14873 NN denotes NF-κB
T6045 14875-14877 TO denotes To
T6046 14878-14885 VB denotes address
T6047 14886-14890 DT denotes this
T6048 14891-14899 NN denotes question
T6049 14899-14900 -COMMA- denotes ,
T6050 14901-14903 PRP denotes we
T6051 14904-14912 VB denotes examined
T6052 14913-14916 DT denotes the
T6053 14917-14932 JJ denotes transcriptional
T6054 14933-14943 NN denotes activation
T6055 14944-14946 IN denotes of
T6056 14947-14950 DT denotes the
T6057 14951-14956 NN denotes HIV-1
T6058 14957-14960 NN denotes LTR
T6059 14960-14961 -COMMA- denotes ,
T6060 14962-14967 WDT denotes which
T6061 14968-14976 VB denotes contains
T6062 14977-14980 CD denotes two
T6063 14981-14987 JJ denotes tandem
T6064 14988-14998 JJ denotes cis-acting
T6065 14999-15004 NN denotes NF-κB
T6066 15005-15012 NN denotes binding
T6067 15013-15018 NN denotes sites
T6068 15019-15026 JJ denotes located
T6069 15027-15034 IN denotes between
T6070 15035-15044 NN denotes positions
T6071 15045-15049 CD denotes −102
T6072 15050-15053 CC denotes and
T6073 15054-15057 CD denotes −81
T6074 15058-15062 IN denotes with
T6075 15063-15070 NN denotes respect
T6076 15071-15073 TO denotes to
T6077 15074-15077 DT denotes the
T6078 15078-15091 NN denotes transcription
T6079 15092-15102 NN denotes initiation
T6080 15103-15107 NN denotes site
T6081 15108-15109 -LRB- denotes [
T6082 15109-15111 CD denotes 21
T6083 15111-15112 -RRB- denotes ]
T6084 15114-15119 NN denotes NF-κB
T6085 15120-15125 VB denotes plays
T6086 15126-15127 DT denotes a
T6087 15128-15135 JJ denotes crucial
T6088 15136-15140 NN denotes role
T6089 15141-15143 IN denotes in
T6090 15144-15154 VB denotes regulating
T6091 15155-15159 NN denotes gene
T6092 15160-15170 NN denotes expression
T6093 15171-15179 VB denotes directed
T6094 15180-15184 IN denotes from
T6095 15185-15188 DT denotes the
T6096 15189-15194 NN denotes HIV-1
T6097 15195-15198 NN denotes LTR
T6098 15199-15201 IN denotes in
T6099 15202-15206 JJ denotes CD4+
T6100 15207-15208 NN denotes T
T6101 15209-15214 NN denotes cells
T6102 15215-15216 -LRB- denotes [
T6103 15216-15218 CD denotes 21
T6104 15218-15219 -RRB- denotes ]
T6105 15221-15235 NN denotes Overexpression
T6106 15236-15238 IN denotes of
T6107 15239-15250 JJ denotes full-length
T6108 15251-15256 NN denotes Foxp3
T6109 15256-15257 -COMMA- denotes ,
T6110 15258-15261 CC denotes but
T6111 15262-15265 RB denotes not
T6112 15266-15270 NN denotes ΔFKH
T6113 15270-15271 -COMMA- denotes ,
T6114 15272-15274 IN denotes in
T6115 15275-15278 NN denotes HEK
T6116 15279-15283 NN denotes 293T
T6117 15284-15289 NN denotes cells
T6118 15290-15293 VB denotes was
T6119 15294-15298 JJ denotes able
T6120 15299-15301 TO denotes to
T6121 15302-15309 VB denotes inhibit
T6122 15310-15315 JJ denotes basal
T6123 15316-15326 NN denotes activation
T6124 15327-15329 IN denotes of
T6125 15330-15333 DT denotes the
T6126 15334-15339 NN denotes HIV-1
T6127 15340-15343 NN denotes LTR
T6128 15344-15345 -LRB- denotes (
T6129 15345-15351 NN denotes Figure
T6130 15352-15354 NN denotes 3A
T6131 15354-15355 -RRB- denotes )
T6132 15355-15356 -COMMA- denotes ,
T6133 15357-15364 JJ denotes similar
T6134 15365-15367 TO denotes to
T6135 15368-15372 WP denotes what
T6136 15373-15376 VB denotes was
T6137 15377-15387 RB denotes previously
T6138 15388-15400 VB denotes demonstrated
T6139 15401-15405 IN denotes with
T6140 15406-15409 DT denotes the
T6141 15410-15419 JJ denotes synthetic
T6142 15420-15425 NN denotes NF-κB
T6143 15426-15434 NN denotes reporter
T6144 15435-15441 NN denotes vector
T6145 15442-15443 -LRB- denotes (
T6146 15443-15449 NN denotes Figure
T6147 15450-15452 NN denotes 2B
T6148 15452-15453 -RRB- denotes )
T6149 15455-15466 RB denotes Furthermore
T6150 15466-15467 -COMMA- denotes ,
T6151 15468-15473 NN denotes HIV-1
T6152 15474-15477 NN denotes LTR
T6153 15478-15488 NN denotes activation
T6154 15489-15492 VB denotes was
T6155 15493-15503 VB denotes suppressed
T6156 15504-15506 IN denotes by
T6157 15507-15518 JJ denotes full-length
T6158 15519-15524 NN denotes Foxp3
T6159 15525-15528 CC denotes and
T6160 15529-15533 NN denotes ΔFKH
T6161 15534-15536 IN denotes in
T6162 15537-15543 NN denotes Jurkat
T6163 15544-15545 NN denotes T
T6164 15546-15551 NN denotes cells
T6165 15552-15553 -LRB- denotes (
T6166 15553-15559 NN denotes Figure
T6167 15560-15562 NN denotes 3B
T6168 15562-15563 -RRB- denotes )
T6169 15565-15567 TO denotes To
T6170 15568-15579 VB denotes demonstrate
T6171 15580-15584 IN denotes that
T6172 15585-15599 JJ denotes Foxp3-mediated
T6173 15600-15605 NN denotes HIV-1
T6174 15606-15609 NN denotes LTR
T6175 15610-15620 NN denotes repression
T6176 15621-15624 VB denotes was
T6177 15625-15635 VB denotes associated
T6178 15636-15640 IN denotes with
T6179 15641-15653 NN denotes interactions
T6180 15654-15658 IN denotes with
T6181 15659-15664 NN denotes NF-κB
T6182 15665-15670 VB denotes bound
T6183 15671-15673 TO denotes to
T6184 15674-15677 DT denotes the
T6185 15678-15683 NN denotes HIV-1
T6186 15684-15687 NN denotes LTR
T6187 15687-15688 -COMMA- denotes ,
T6188 15689-15691 PRP denotes we
T6189 15692-15700 VB denotes compared
T6190 15701-15706 JJ denotes basal
T6191 15707-15717 NN denotes activation
T6192 15718-15720 IN denotes of
T6193 15721-15724 DT denotes the
T6194 15725-15730 NN denotes HIV-1
T6195 15731-15734 NN denotes LTR
T6196 15735-15737 CC denotes or
T6197 15738-15740 DT denotes an
T6198 15741-15750 JJ denotes identical
T6199 15751-15756 NN denotes HIV-1
T6200 15757-15760 NN denotes LTR
T6201 15761-15768 VB denotes lacking
T6202 15769-15772 DT denotes the
T6203 15773-15778 NN denotes NF-κB
T6204 15779-15784 NN denotes sites
T6205 15785-15792 JJ denotes located
T6206 15793-15800 IN denotes between
T6207 15801-15805 CD denotes −102
T6208 15806-15809 CC denotes and
T6209 15810-15813 CD denotes −81
T6210 15814-15815 -LRB- denotes (
T6211 15815-15820 NN denotes HIV-1
T6212 15821-15825 NN denotes Δ-κB
T6213 15826-15829 NN denotes LTR
T6214 15829-15830 -RRB- denotes )
T6215 15831-15832 -LRB- denotes (
T6216 15832-15838 NN denotes Figure
T6217 15839-15841 NN denotes 3C
T6218 15841-15842 -RRB- denotes )
T6219 15844-15848 DT denotes This
T6220 15849-15855 JJ denotes mutant
T6221 15856-15861 NN denotes HIV-1
T6222 15862-15865 NN denotes LTR
T6223 15866-15875 NN denotes construct
T6224 15876-15885 VB denotes exhibited
T6225 15886-15893 VB denotes reduced
T6226 15894-15900 NN denotes levels
T6227 15901-15903 IN denotes of
T6228 15904-15917 NN denotes transcription
T6229 15918-15926 VB denotes compared
T6230 15927-15929 TO denotes to
T6231 15930-15933 DT denotes the
T6232 15934-15942 JJ denotes parental
T6233 15943-15948 NN denotes HIV-1
T6234 15949-15952 NN denotes LTR
T6235 15953-15955 IN denotes in
T6236 15956-15964 VB denotes purified
T6237 15965-15972 JJ denotes healthy
T6238 15973-15978 NN denotes donor
T6239 15979-15983 JJ denotes CD4+
T6240 15984-15985 NN denotes T
T6241 15986-15991 NN denotes cells
T6242 15992-15993 -LRB- denotes (
T6243 15993-16004 JJ denotes unpublished
T6244 16005-16009 NN denotes data
T6245 16009-16010 -RRB- denotes )
T6246 16012-16019 RB denotes However
T6247 16019-16020 -COMMA- denotes ,
T6248 16021-16029 RB denotes directly
T6249 16030-16039 VB denotes comparing
T6250 16040-16043 DT denotes the
T6251 16044-16050 NN denotes effect
T6252 16051-16053 IN denotes of
T6253 16054-16059 NN denotes Foxp3
T6254 16060-16074 NN denotes overexpression
T6255 16075-16077 IN denotes on
T6256 16078-16081 DT denotes the
T6257 16082-16092 NN denotes activation
T6258 16093-16095 IN denotes of
T6259 16096-16101 DT denotes these
T6260 16102-16105 CD denotes two
T6261 16106-16111 JJ denotes viral
T6262 16112-16121 NN denotes promoters
T6263 16122-16134 VB denotes demonstrated
T6264 16135-16139 IN denotes that
T6265 16140-16145 NN denotes Foxp3
T6266 16146-16149 VB denotes was
T6267 16150-16154 RB denotes more
T6268 16155-16162 JJ denotes capable
T6269 16163-16165 IN denotes of
T6270 16166-16177 VB denotes suppressing
T6271 16178-16193 JJ denotes transcriptional
T6272 16194-16204 NN denotes activation
T6273 16205-16207 IN denotes of
T6274 16208-16211 DT denotes the
T6275 16212-16217 NN denotes HIV-1
T6276 16218-16221 NN denotes LTR
T6277 16222-16223 -LRB- denotes (
T6278 16223-16229 NN denotes Figure
T6279 16230-16232 NN denotes 3D
T6280 16232-16233 -RRB- denotes )
T6281 16234-16242 VB denotes compared
T6282 16243-16245 TO denotes to
T6283 16246-16249 DT denotes the
T6284 16250-16257 VB denotes mutated
T6285 16258-16263 NN denotes HIV-1
T6286 16264-16267 NN denotes LTR
T6287 16268-16269 -LRB- denotes (
T6288 16269-16275 NN denotes Figure
T6289 16276-16278 NN denotes 3E
T6290 16278-16279 -RRB- denotes )
T6291 16281-16286 DT denotes These
T6292 16287-16294 NN denotes results
T6293 16295-16302 VB denotes suggest
T6294 16303-16307 IN denotes that
T6295 16308-16313 NN denotes Foxp3
T6296 16314-16329 NN denotes down-regulation
T6297 16330-16332 IN denotes of
T6298 16333-16338 NN denotes HIV-1
T6299 16339-16342 NN denotes LTR
T6300 16343-16353 NN denotes activation
T6301 16354-16357 VB denotes was
T6302 16358-16366 VB denotes mediated
T6303 16367-16369 IN denotes at
T6304 16370-16375 JJ denotes least
T6305 16376-16378 IN denotes in
T6306 16379-16383 NN denotes part
T6307 16384-16386 IN denotes by
T6308 16387-16397 JJ denotes cis-acting
T6309 16398-16403 NN denotes NF-κB
T6310 16404-16411 NN denotes binding
T6311 16412-16417 NN denotes sites
T6312 16419-16427 JJ denotes Residual
T6313 16428-16434 NN denotes levels
T6314 16435-16437 IN denotes of
T6315 16438-16448 NN denotes inhibition
T6316 16449-16451 IN denotes of
T6317 16452-16455 DT denotes the
T6318 16456-16461 NN denotes HIV-1
T6319 16462-16466 NN denotes Δ-κB
T6320 16467-16470 NN denotes LTR
T6321 16471-16473 IN denotes by
T6322 16474-16479 NN denotes Foxp3
T6323 16480-16483 MD denotes may
T6324 16484-16486 VB denotes be
T6325 16487-16490 JJ denotes due
T6326 16491-16493 TO denotes to
T6327 16494-16499 NN denotes NF-AT
T6328 16500-16507 NN denotes binding
T6329 16508-16513 NN denotes sites
T6330 16514-16521 JJ denotes located
T6331 16522-16530 RB denotes upstream
T6332 16531-16533 IN denotes of
T6333 16534-16537 DT denotes the
T6334 16538-16543 NN denotes NF-κB
T6335 16544-16549 NN denotes sites
T6336 16550-16556 IN denotes within
T6337 16557-16560 DT denotes the
T6338 16561-16566 NN denotes HIV-1
T6339 16567-16570 NN denotes LTR
T6340 16571-16572 -LRB- denotes [
T6341 16572-16577 CD denotes 22,23
T6342 16577-16578 -RRB- denotes ]
T7542 17683-17686 DT denotes The
T7543 17687-17702 NNP denotes Transactivation
T7544 17703-17712 NN denotes Functions
T7545 17713-17715 IN denotes of
T7546 17716-17722 NN denotes HTLV-I
T7547 17723-17726 NN denotes Tax
T7548 17727-17730 VB denotes Are
T7549 17731-17741 VB denotes Suppressed
T7550 17742-17744 IN denotes by
T7551 17745-17750 NN denotes Foxp3
T7552 17751-17759 JJ denotes Previous
T7553 17760-17767 NN denotes studies
T7554 17768-17770 IN denotes by
T7555 17771-17779 NNP denotes Bettelli
T7556 17780-17783 CC denotes and
T7557 17784-17794 NN denotes colleagues
T7558 17795-17799 VB denotes have
T7559 17800-17812 VB denotes demonstrated
T7560 17813-17817 IN denotes that
T7561 17818-17823 NN denotes Foxp3
T7562 17824-17827 MD denotes can
T7563 17828-17835 VB denotes repress
T7564 17836-17840 CC denotes both
T7565 17841-17844 DT denotes the
T7566 17845-17850 JJ denotes basal
T7567 17851-17857 NN denotes levels
T7568 17858-17860 IN denotes of
T7569 17861-17866 NN denotes NF-κB
T7570 17867-17877 NN denotes activation
T7571 17878-17880 RB denotes as
T7572 17881-17885 RB denotes well
T7573 17886-17888 IN denotes as
T7574 17889-17894 NN denotes tumor
T7575 17895-17903 NN denotes necrosis
T7576 17904-17923 JJ denotes factor-α-stimulated
T7577 17924-17929 NN denotes NF-κB
T7578 17930-17940 NN denotes activation
T7579 17941-17942 -LRB- denotes [
T7580 17942-17944 CD denotes 15
T7581 17944-17945 -RRB- denotes ]
T7582 17947-17950 PRP-DOLLAR- denotes Our
T7583 17951-17955 JJ denotes next
T7584 17956-17960 NN denotes step
T7585 17961-17964 VB denotes was
T7586 17965-17967 TO denotes to
T7587 17968-17977 VB denotes determine
T7588 17978-17985 IN denotes whether
T7589 17986-17991 NN denotes Foxp3
T7590 17992-17997 MD denotes could
T7591 17998-18002 RB denotes also
T7592 18003-18011 VB denotes suppress
T7593 18012-18015 DT denotes the
T7594 18016-18026 NN denotes activation
T7595 18027-18029 IN denotes of
T7596 18030-18035 NN denotes NF-κB
T7597 18036-18042 VB denotes caused
T7598 18043-18045 IN denotes by
T7599 18046-18047 DT denotes a
T7600 18048-18054 JJ denotes strong
T7601 18055-18060 JJ denotes viral
T7602 18061-18075 NN denotes transactivator
T7603 18076-18083 NN denotes protein
T7604 18085-18091 NN denotes HTLV-I
T7605 18092-18099 VB denotes encodes
T7606 18100-18101 DT denotes a
T7607 18102-18117 JJ denotes multifunctional
T7608 18118-18132 NN denotes transactivator
T7609 18133-18140 NN denotes protein
T7610 18140-18141 -COMMA- denotes ,
T7611 18142-18145 NN denotes Tax
T7612 18145-18146 -COMMA- denotes ,
T7613 18147-18154 JJ denotes capable
T7614 18155-18157 IN denotes of
T7615 18158-18168 VB denotes activating
T7616 18169-18173 CC denotes both
T7617 18174-18177 DT denotes the
T7618 18178-18183 NN denotes NF-κB
T7619 18184-18187 CC denotes and
T7620 18188-18192 NN denotes CREB
T7621 18193-18201 NN denotes pathways
T7622 18202-18203 -LRB- denotes [
T7623 18203-18208 CD denotes 24–29
T7624 18208-18209 -RRB- denotes ]
T7625 18211-18216 IN denotes Since
T7626 18217-18220 DT denotes the
T7627 18221-18227 NN denotes HTLV-I
T7628 18228-18231 NN denotes Tax
T7629 18232-18239 NN denotes protein
T7630 18240-18243 MD denotes can
T7631 18244-18252 VB denotes function
T7632 18253-18255 IN denotes at
T7633 18256-18264 JJ denotes multiple
T7634 18265-18271 NN denotes levels
T7635 18272-18274 IN denotes in
T7636 18275-18279 CC denotes both
T7637 18280-18283 DT denotes the
T7638 18284-18293 NN denotes cytoplasm
T7639 18294-18297 CC denotes and
T7640 18298-18301 DT denotes the
T7641 18302-18309 NN denotes nucleus
T7642 18310-18312 TO denotes to
T7643 18313-18322 VB denotes stimulate
T7644 18323-18333 NN denotes activation
T7645 18334-18336 IN denotes of
T7646 18337-18342 NN denotes NF-κB
T7647 18343-18344 -LRB- denotes [
T7648 18344-18349 CD denotes 28,29
T7649 18349-18350 -RRB- denotes ]
T7650 18350-18351 -COMMA- denotes ,
T7651 18352-18354 PRP denotes we
T7652 18355-18367 VB denotes hypothesized
T7653 18368-18372 IN denotes that
T7654 18373-18387 NN denotes overexpression
T7655 18388-18390 IN denotes of
T7656 18391-18396 NN denotes Foxp3
T7657 18397-18400 MD denotes may
T7658 18401-18410 VB denotes interfere
T7659 18411-18415 IN denotes with
T7660 18416-18420 DT denotes this
T7661 18421-18428 NN denotes process
T7662 18430-18437 RB denotes However
T7663 18437-18438 -COMMA- denotes ,
T7664 18439-18444 IN denotes since
T7665 18445-18458 JJ denotes Tax-dependent
T7666 18459-18465 NN denotes HTLV-I
T7667 18466-18470 NN denotes gene
T7668 18471-18481 NN denotes expression
T7669 18482-18484 VB denotes is
T7670 18485-18496 JJ denotes independent
T7671 18497-18499 IN denotes of
T7672 18500-18505 NN denotes NF-κB
T7673 18506-18507 -LRB- denotes [
T7674 18507-18509 CD denotes 18
T7675 18509-18510 -RRB- denotes ]
T7676 18510-18511 -COMMA- denotes ,
T7677 18512-18514 PRP denotes we
T7678 18515-18519 RB denotes also
T7679 18520-18532 VB denotes hypothesized
T7680 18533-18537 IN denotes that
T7681 18538-18543 NN denotes Foxp3
T7682 18544-18549 MD denotes would
T7683 18550-18553 RB denotes not
T7684 18554-18560 VB denotes affect
T7685 18561-18574 JJ denotes Tax-dependent
T7686 18575-18585 NN denotes activation
T7687 18586-18588 IN denotes of
T7688 18589-18592 DT denotes the
T7689 18593-18599 NN denotes HTLV-I
T7690 18600-18603 NN denotes LTR
T7691 18605-18607 TO denotes To
T7692 18608-18612 VB denotes test
T7693 18613-18618 DT denotes these
T7694 18619-18629 NN denotes hypotheses
T7695 18629-18630 -COMMA- denotes ,
T7696 18631-18633 PRP denotes we
T7697 18634-18647 VB denotes overexpressed
T7698 18648-18654 NN denotes HTLV-I
T7699 18655-18658 NN denotes Tax
T7700 18658-18659 -COMMA- denotes ,
T7701 18660-18671 JJ denotes full-length
T7702 18672-18677 NN denotes Foxp3
T7703 18677-18678 -COMMA- denotes ,
T7704 18679-18685 CC denotes and/or
T7705 18686-18690 NN denotes ΔFKH
T7706 18691-18693 IN denotes in
T7707 18694-18697 NN denotes HEK
T7708 18698-18702 NN denotes 293T
T7709 18703-18708 NN denotes cells
T7710 18709-18722 VB denotes cotransfected
T7711 18723-18727 IN denotes with
T7712 18728-18730 DT denotes an
T7713 18731-18737 NN denotes HTLV-I
T7714 18738-18741 NN denotes LTR
T7715 18742-18744 CC denotes or
T7716 18745-18750 NN denotes NF-κB
T7717 18751-18759 NN denotes reporter
T7718 18760-18766 NN denotes vector
T7719 18768-18770 IN denotes As
T7720 18771-18776 VB denotes shown
T7721 18777-18779 IN denotes in
T7722 18780-18786 NN denotes Figure
T7723 18787-18789 NN denotes 4A
T7724 18789-18790 -COMMA- denotes ,
T7725 18791-18797 NN denotes HTLV-I
T7726 18798-18801 NN denotes Tax
T7727 18802-18810 RB denotes strongly
T7728 18811-18823 VB denotes up-regulated
T7729 18824-18839 JJ denotes NF-κB-dependent
T7730 18840-18855 JJ denotes transcriptional
T7731 18856-18866 NN denotes activation
T7732 18867-18868 -LRB- denotes (
T7733 18868-18876 JJ denotes ~60-fold
T7734 18876-18877 -RRB- denotes )
T7735 18879-18892 RB denotes Interestingly
T7736 18892-18893 -COMMA- denotes ,
T7737 18894-18908 NN denotes overexpression
T7738 18909-18911 IN denotes of
T7739 18912-18917 NN denotes Foxp3
T7740 18917-18918 -COMMA- denotes ,
T7741 18919-18922 CC denotes but
T7742 18923-18926 RB denotes not
T7743 18927-18931 NN denotes ΔFKH
T7744 18931-18932 -COMMA- denotes ,
T7745 18933-18943 VB denotes suppressed
T7746 18944-18956 JJ denotes Tax-mediated
T7747 18957-18967 NN denotes activation
T7748 18968-18970 IN denotes of
T7749 18971-18986 JJ denotes NF-κB-dependent
T7750 18987-19000 NN denotes transcription
T7751 19002-19007 DT denotes These
T7752 19008-19020 NN denotes observations
T7753 19021-19028 RB denotes further
T7754 19029-19036 VB denotes suggest
T7755 19037-19041 IN denotes that
T7756 19042-19045 DT denotes the
T7757 19046-19063 JJ denotes carboxyl-terminal
T7758 19064-19067 NN denotes FKH
T7759 19068-19074 NN denotes domain
T7760 19075-19077 VB denotes is
T7761 19078-19086 VB denotes required
T7762 19087-19090 IN denotes for
T7763 19091-19101 VB denotes inhibiting
T7764 19102-19112 NN denotes activation
T7765 19113-19115 IN denotes of
T7766 19116-19121 NN denotes NF-κB
T7767 19122-19124 IN denotes in
T7768 19125-19128 DT denotes the
T7769 19129-19137 NN denotes presence
T7770 19138-19140 IN denotes of
T7771 19141-19144 NN denotes Tax
T7772 19145-19147 IN denotes in
T7773 19148-19151 NN denotes HEK
T7774 19152-19156 NN denotes 293T
T7775 19157-19162 NN denotes cells
T7776 19162-19163 -COMMA- denotes ,
T7777 19164-19174 RB denotes strikingly
T7778 19175-19182 JJ denotes similar
T7779 19183-19185 TO denotes to
T7780 19186-19189 DT denotes the
T7781 19190-19202 NN denotes requirements
T7782 19203-19205 IN denotes of
T7783 19206-19211 NN denotes Foxp3
T7784 19212-19222 NN denotes inhibition
T7785 19223-19225 IN denotes of
T7786 19226-19231 JJ denotes basal
T7787 19232-19237 NN denotes NF-κB
T7788 19238-19248 NN denotes activation
T7789 19249-19254 VB denotes shown
T7790 19255-19257 IN denotes in
T7791 19258-19264 NN denotes Figure
T7792 19265-19267 NN denotes 2B
T7793 19269-19284 NN denotes Transactivation
T7794 19285-19287 IN denotes of
T7795 19288-19291 DT denotes the
T7796 19292-19298 NN denotes HTLV-I
T7797 19299-19302 NN denotes LTR
T7798 19303-19306 VB denotes was
T7799 19307-19317 VB denotes stimulated
T7800 19318-19323 IN denotes about
T7801 19324-19331 RB denotes 55-fold
T7802 19332-19334 IN denotes by
T7803 19335-19349 NN denotes overexpression
T7804 19350-19352 IN denotes of
T7805 19353-19356 NN denotes Tax
T7806 19357-19358 -LRB- denotes (
T7807 19358-19364 NN denotes Figure
T7808 19365-19367 NN denotes 4B
T7809 19367-19368 -RRB- denotes )
T7810 19368-19369 -COMMA- denotes ,
T7811 19370-19375 IN denotes while
T7812 19376-19388 NN denotes transfection
T7813 19389-19391 IN denotes of
T7814 19392-19397 NN denotes Foxp3
T7815 19398-19408 VB denotes suppressed
T7816 19409-19422 JJ denotes Tax-dependent
T7817 19423-19429 NN denotes HTLV-I
T7818 19430-19433 NN denotes LTR
T7819 19434-19444 NN denotes activation
T7820 19444-19445 -COMMA- denotes ,
T7821 19446-19454 IN denotes although
T7822 19455-19461 NN denotes HTLV-I
T7823 19462-19465 NN denotes LTR
T7824 19466-19476 NN denotes activation
T7825 19477-19479 IN denotes in
T7826 19480-19483 DT denotes the
T7827 19484-19492 NN denotes presence
T7828 19493-19495 CC denotes or
T7829 19496-19503 NN denotes absence
T7830 19504-19506 IN denotes of
T7831 19507-19510 NN denotes Tax
T7832 19511-19513 VB denotes is
T7833 19514-19525 JJ denotes independent
T7834 19526-19528 IN denotes of
T7835 19529-19534 NN denotes NF-κB
T7836 19535-19537 CC denotes or
T7837 19538-19543 NN denotes NF-AT
T7838 19544-19545 -LRB- denotes (
T7839 19545-19552 DT denotes another
T7840 19553-19568 JJ denotes transcriptional
T7841 19569-19578 NN denotes activator
T7842 19579-19584 VB denotes known
T7843 19585-19587 TO denotes to
T7844 19588-19596 VB denotes interact
T7845 19597-19601 IN denotes with
T7846 19602-19607 NN denotes Foxp3
T7847 19607-19608 -RRB- denotes )
T7848 19610-19621 RB denotes Furthermore
T7849 19621-19622 -COMMA- denotes ,
T7850 19623-19637 NN denotes overexpression
T7851 19638-19640 IN denotes of
T7852 19641-19645 NN denotes ΔFKH
T7853 19646-19650 RB denotes also
T7854 19651-19654 VB denotes led
T7855 19655-19657 TO denotes to
T7856 19658-19669 NN denotes suppression
T7857 19670-19672 IN denotes of
T7858 19673-19679 NN denotes HTLV-I
T7859 19680-19695 NN denotes transactivation
T7860 19696-19698 IN denotes by
T7861 19699-19702 NN denotes Tax
T7862 19703-19705 TO denotes to
T7863 19706-19707 DT denotes a
T7864 19708-19715 JJ denotes similar
T7865 19716-19722 NN denotes extent
T7866 19723-19725 IN denotes as
T7867 19726-19737 JJ denotes full-length
T7868 19738-19743 NN denotes Foxp3
T7869 19744-19745 -LRB- denotes (
T7870 19745-19751 NN denotes Figure
T7871 19752-19754 NN denotes 4B
T7872 19754-19755 -RRB- denotes )
T7873 19757-19760 DT denotes The
T7874 19761-19772 JJ denotes suppressive
T7875 19773-19780 NN denotes effects
T7876 19781-19786 VB denotes shown
T7877 19787-19789 IN denotes in
T7878 19790-19796 NN denotes Figure
T7879 19797-19799 NN denotes 4A
T7880 19800-19803 CC denotes and
T7881 19804-19806 NN denotes 4B
T7882 19807-19811 VB denotes were
T7883 19812-19815 RB denotes not
T7884 19816-19819 DT denotes the
T7885 19820-19826 NN denotes result
T7886 19827-19829 IN denotes of
T7887 19830-19835 NN denotes Foxp3
T7888 19836-19851 VB denotes down-regulating
T7889 19852-19855 DT denotes the
T7890 19856-19866 NN denotes expression
T7891 19867-19869 IN denotes of
T7892 19870-19873 DT denotes the
T7893 19874-19885 VB denotes transfected
T7894 19886-19889 NN denotes Tax
T7895 19890-19897 NN denotes plasmid
T7896 19898-19900 IN denotes as
T7897 19901-19911 VB denotes determined
T7898 19912-19914 IN denotes by
T7899 19915-19924 JJ denotes real-time
T7900 19925-19931 NN denotes RT-PCR
T7901 19932-19933 -LRB- denotes (
T7902 19933-19939 NN denotes Figure
T7903 19940-19942 NN denotes 4C
T7904 19942-19943 -RRB- denotes )
T7905 19945-19950 DT denotes These
T7906 19951-19958 NN denotes results
T7907 19959-19967 RB denotes strongly
T7908 19968-19975 VB denotes suggest
T7909 19976-19980 IN denotes that
T7910 19981-19986 NN denotes Foxp3
T7911 19987-19996 VB denotes interacts
T7912 19997-20001 IN denotes with
T7913 20002-20017 JJ denotes transcriptional
T7914 20018-20028 NN denotes regulators
T7915 20029-20031 IN denotes in
T7916 20032-20040 NN denotes addition
T7917 20041-20043 TO denotes to
T7918 20044-20049 NN denotes NF-κB
T7919 20050-20053 CC denotes and
T7920 20054-20059 NN denotes NF-AT
T7921 20059-20060 -COMMA- denotes ,
T7922 20061-20064 CC denotes and
T7923 20065-20069 IN denotes that
T7924 20070-20073 DT denotes the
T7925 20074-20091 JJ denotes carboxyl-terminal
T7926 20092-20095 NN denotes FKH
T7927 20096-20102 NN denotes domain
T7928 20102-20103 -COMMA- denotes ,
T7929 20104-20107 CC denotes and
T7930 20108-20117 RB denotes therefore
T7931 20118-20130 NN denotes localization
T7932 20131-20133 TO denotes to
T7933 20134-20137 DT denotes the
T7934 20138-20145 NN denotes nucleus
T7935 20145-20146 -COMMA- denotes ,
T7936 20147-20150 VB denotes are
T7937 20151-20154 RB denotes not
T7938 20155-20163 VB denotes required
T7939 20164-20167 IN denotes for
T7940 20168-20178 NN denotes inhibition
T7941 20179-20181 IN denotes of
T7942 20182-20194 JJ denotes Tax-mediated
T7943 20195-20201 NN denotes HTLV-I
T7944 20202-20205 NN denotes LTR
T7945 20206-20216 NN denotes activation
T7946 20217-20218 -LRB- denotes (
T7947 20218-20222 RB denotes even
T7948 20223-20225 IN denotes in
T7949 20226-20229 NN denotes HEK
T7950 20230-20234 NN denotes 293T
T7951 20235-20240 NN denotes cells
T7952 20240-20241 -RRB- denotes )
T7953 21522-21524 TO denotes To
T7954 21525-21534 VB denotes determine
T7955 21535-21542 IN denotes whether
T7956 21543-21548 NN denotes Foxp3
T7957 21549-21558 VB denotes inhibited
T7958 21559-21562 DT denotes the
T7959 21563-21578 NN denotes transactivation
T7960 21579-21588 NN denotes functions
T7961 21589-21591 IN denotes of
T7962 21592-21595 NN denotes Tax
T7963 21596-21598 IN denotes by
T7964 21599-21607 RB denotes directly
T7965 21608-21619 VB denotes associating
T7966 21620-21624 IN denotes with
T7967 21625-21629 DT denotes this
T7968 21630-21635 JJ denotes viral
T7969 21636-21643 NN denotes protein
T7970 21643-21644 -COMMA- denotes ,
T7971 21645-21647 PRP denotes we
T7972 21648-21657 VB denotes generated
T7973 21658-21660 DT denotes an
T7974 21661-21671 NN denotes expression
T7975 21672-21678 NN denotes vector
T7976 21679-21681 IN denotes in
T7977 21682-21687 WDT denotes which
T7978 21688-21694 NN denotes HTLV-I
T7979 21695-21698 NN denotes Tax
T7980 21699-21702 VB denotes was
T7981 21703-21708 VB denotes fused
T7982 21709-21717 JJ denotes in-frame
T7983 21718-21720 TO denotes to
T7984 21721-21724 DT denotes the
T7985 21725-21733 NN denotes carboxyl
T7986 21734-21742 NN denotes terminus
T7987 21743-21745 IN denotes of
T7988 21746-21749 DT denotes the
T7989 21750-21754 NN denotes Gal4
T7990 21755-21766 JJ denotes DNA-binding
T7991 21767-21773 NN denotes domain
T7992 21774-21775 -LRB- denotes (
T7993 21775-21782 NN denotes Gal4-BD
T7994 21782-21783 -RRB- denotes )
T7995 21785-21789 DT denotes This
T7996 21790-21801 NN denotes Gal4-BD-Tax
T7997 21802-21808 NN denotes fusion
T7998 21809-21816 NN denotes protein
T7999 21817-21826 VB denotes activated
T8000 21827-21840 NN denotes transcription
T8001 21841-21843 IN denotes of
T8002 21844-21845 DT denotes a
T8003 21846-21855 JJ denotes synthetic
T8004 21856-21864 NN denotes promoter
T8005 21865-21875 VB denotes containing
T8006 21876-21880 CD denotes five
T8007 21881-21885 NN denotes Gal4
T8008 21886-21893 NN denotes binding
T8009 21894-21899 NN denotes sites
T8010 21899-21900 -COMMA- denotes ,
T8011 21901-21906 IN denotes while
T8012 21907-21914 NN denotes Gal4-BD
T8013 21915-21918 VB denotes was
T8014 21919-21931 JJ denotes insufficient
T8015 21932-21934 TO denotes to
T8016 21935-21944 VB denotes stimulate
T8017 21945-21958 NN denotes transcription
T8018 21959-21961 IN denotes by
T8019 21962-21968 PRP denotes itself
T8020 21969-21970 -LRB- denotes (
T8021 21970-21976 NN denotes Figure
T8022 21977-21979 NN denotes 4D
T8023 21979-21980 -RRB- denotes )
T8024 21982-21997 NN denotes Transactivation
T8025 21998-22000 IN denotes of
T8026 22001-22004 DT denotes the
T8027 22005-22019 JJ denotes Gal4-resposive
T8028 22020-22028 NN denotes promoter
T8029 22029-22031 IN denotes by
T8030 22032-22043 NN denotes Gal4-BD-Tax
T8031 22044-22052 VB denotes remained
T8032 22053-22063 RB denotes relatively
T8033 22064-22074 JJ denotes unaffected
T8034 22075-22077 IN denotes by
T8035 22078-22092 NN denotes overexpression
T8036 22093-22095 IN denotes of
T8037 22096-22102 CC denotes either
T8038 22103-22107 NN denotes EGFP
T8039 22108-22109 -LRB- denotes (
T8040 22109-22116 NN denotes control
T8041 22116-22117 -RRB- denotes )
T8042 22117-22118 -COMMA- denotes ,
T8043 22119-22124 NN denotes Foxp3
T8044 22124-22125 -COMMA- denotes ,
T8045 22126-22128 CC denotes or
T8046 22129-22133 NN denotes ΔFKH
T8047 22133-22134 -COMMA- denotes ,
T8048 22135-22145 VB denotes suggesting
T8049 22146-22150 IN denotes that
T8050 22151-22156 NN denotes Foxp3
T8051 22157-22161 VB denotes does
T8052 22162-22165 RB denotes not
T8053 22166-22173 VB denotes repress
T8054 22174-22177 NN denotes Tax
T8055 22178-22193 NN denotes transactivation
T8056 22194-22196 IN denotes by
T8057 22197-22205 RB denotes directly
T8058 22206-22217 VB denotes interfacing
T8059 22218-22222 IN denotes with
T8060 22223-22226 DT denotes the
T8061 22227-22233 NN denotes HTLV-I
T8062 22234-22237 NN denotes Tax
T8063 22238-22245 NN denotes protein
T8064 22247-22249 TO denotes To
T8065 22250-22257 VB denotes confirm
T8066 22258-22262 IN denotes that
T8067 22263-22268 NN denotes Foxp3
T8068 22269-22272 VB denotes had
T8069 22273-22274 DT denotes a
T8070 22275-22281 JJ denotes direct
T8071 22282-22288 NN denotes effect
T8072 22289-22291 IN denotes on
T8073 22292-22298 NN denotes HTLV-I
T8074 22299-22310 NN denotes replication
T8075 22310-22311 -COMMA- denotes ,
T8076 22312-22314 PRP denotes we
T8077 22315-22326 VB denotes transfected
T8078 22327-22330 NN denotes HEK
T8079 22331-22335 NN denotes 293T
T8080 22336-22341 NN denotes cells
T8081 22342-22346 IN denotes with
T8082 22347-22348 DT denotes a
T8083 22349-22367 JJ denotes well-characterized
T8084 22368-22374 NN denotes HTLV-I
T8085 22375-22385 JJ denotes infectious
T8086 22386-22395 JJ denotes molecular
T8087 22396-22401 NN denotes clone
T8088 22402-22403 -LRB- denotes (
T8089 22403-22409 VB denotes termed
T8090 22410-22413 NN denotes ACH
T8091 22413-22414 -RRB- denotes )
T8092 22415-22416 -LRB- denotes [
T8093 22416-22418 CD denotes 30
T8094 22418-22419 -RRB- denotes ]
T8095 22420-22422 IN denotes in
T8096 22423-22426 DT denotes the
T8097 22427-22435 NN denotes presence
T8098 22436-22438 IN denotes of
T8099 22439-22450 JJ denotes full-length
T8100 22451-22456 NN denotes Foxp3
T8101 22456-22457 -COMMA- denotes ,
T8102 22458-22462 NN denotes ΔFKH
T8103 22462-22463 -COMMA- denotes ,
T8104 22464-22466 CC denotes or
T8105 22467-22474 NN denotes control
T8106 22475-22481 NN denotes vector
T8107 22483-22486 NN denotes ACH
T8108 22487-22490 VB denotes has
T8109 22491-22495 VB denotes been
T8110 22496-22506 RB denotes previously
T8111 22507-22512 VB denotes shown
T8112 22513-22515 TO denotes to
T8113 22516-22522 VB denotes direct
T8114 22523-22526 DT denotes the
T8115 22527-22537 NN denotes expression
T8116 22538-22540 IN denotes of
T8117 22541-22546 JJ denotes viral
T8118 22547-22555 NN denotes antigens
T8119 22555-22556 -COMMA- denotes ,
T8120 22557-22564 VB denotes produce
T8121 22565-22575 JJ denotes infectious
T8122 22576-22581 NN denotes virus
T8123 22581-22582 -COMMA- denotes ,
T8124 22583-22586 CC denotes and
T8125 22587-22596 VB denotes transform
T8126 22597-22601 JJ denotes CD4+
T8127 22602-22603 NN denotes T
T8128 22604-22609 NN denotes cells
T8129 22610-22614 CC denotes both
T8130 22615-22617 FW denotes in
T8131 22618-22623 FW denotes vitro
T8132 22624-22627 CC denotes and
T8133 22628-22630 FW denotes in
T8134 22631-22635 FW denotes vivo
T8135 22636-22637 -LRB- denotes [
T8136 22637-22642 CD denotes 31,32
T8137 22642-22643 -RRB- denotes ]
T8138 22645-22650 IN denotes After
T8139 22651-22653 CD denotes 24
T8140 22654-22655 NN denotes h
T8141 22655-22656 -COMMA- denotes ,
T8142 22657-22660 DT denotes the
T8143 22661-22667 NN denotes amount
T8144 22668-22670 IN denotes of
T8145 22671-22676 JJ denotes viral
T8146 22677-22684 NN denotes antigen
T8147 22685-22695 NN denotes expression
T8148 22695-22696 -COMMA- denotes ,
T8149 22697-22699 IN denotes in
T8150 22700-22704 DT denotes this
T8151 22705-22709 NN denotes case
T8152 22710-22713 NN denotes Tax
T8153 22714-22718 NN denotes mRNA
T8154 22718-22719 -COMMA- denotes ,
T8155 22720-22723 VB denotes was
T8156 22724-22732 VB denotes detected
T8157 22733-22735 IN denotes by
T8158 22736-22737 DT denotes a
T8159 22738-22747 JJ denotes sensitive
T8160 22748-22757 JJ denotes real-time
T8161 22758-22764 NN denotes RT-PCR
T8162 22765-22770 NN denotes assay
T8163 22772-22774 IN denotes As
T8164 22775-22786 VB denotes illustrated
T8165 22787-22789 IN denotes in
T8166 22790-22796 NN denotes Figure
T8167 22797-22798 CD denotes 5
T8168 22798-22799 -COMMA- denotes ,
T8169 22800-22803 DT denotes the
T8170 22804-22809 NN denotes level
T8171 22810-22812 IN denotes of
T8172 22813-22816 NN denotes Tax
T8173 22817-22821 NN denotes mRNA
T8174 22822-22833 VB denotes synthesized
T8175 22834-22838 IN denotes from
T8176 22839-22842 NN denotes ACH
T8177 22843-22846 VB denotes was
T8178 22847-22861 VB denotes down-regulated
T8179 22862-22864 IN denotes in
T8180 22865-22868 DT denotes the
T8181 22869-22877 NN denotes presence
T8182 22878-22880 IN denotes of
T8183 22881-22886 NN denotes Foxp3
T8184 22887-22895 VB denotes compared
T8185 22896-22898 TO denotes to
T8186 22899-22902 DT denotes the
T8187 22903-22908 NN denotes level
T8188 22909-22917 VB denotes produced
T8189 22918-22920 IN denotes in
T8190 22921-22924 DT denotes the
T8191 22925-22933 NN denotes presence
T8192 22934-22936 IN denotes of
T8193 22937-22940 DT denotes the
T8194 22941-22948 NN denotes control
T8195 22949-22956 NN denotes vector.
T8196 22957-22961 NN denotes ΔFKH
T8197 22962-22965 VB denotes did
T8198 22966-22969 RB denotes not
T8199 22970-22974 VB denotes have
T8200 22975-22976 DT denotes a
T8201 22977-22988 JJ denotes discernable
T8202 22989-22995 NN denotes affect
T8203 22996-22998 IN denotes on
T8204 22999-23002 NN denotes Tax
T8205 23003-23013 NN denotes expression
T8206 23015-23020 DT denotes These
T8207 23021-23025 NN denotes data
T8208 23026-23034 VB denotes indicate
T8209 23035-23039 IN denotes that
T8210 23040-23045 NN denotes Foxp3
T8211 23046-23048 VB denotes is
T8212 23049-23056 JJ denotes capable
T8213 23057-23059 IN denotes of
T8214 23060-23070 VB denotes repressing
T8215 23071-23074 DT denotes the
T8216 23075-23085 NN denotes expression
T8217 23086-23088 IN denotes of
T8218 23089-23092 NN denotes Tax
T8219 23093-23097 IN denotes from
T8220 23098-23100 DT denotes an
T8221 23101-23111 JJ denotes infectious
T8222 23112-23118 NN denotes HTLV-I
T8223 23119-23128 JJ denotes molecular
T8224 23129-23134 NN denotes clone
T9285 23569-23578 VB denotes Increased
T9286 23579-23584 NN denotes Foxp3
T9287 23585-23592 NN denotes Protein
T9288 23593-23603 NN denotes Expression
T9289 23604-23606 VB denotes Is
T9290 23607-23617 VB denotes Associated
T9291 23618-23622 IN denotes with
T9292 23623-23626 JJ denotes Low
T9293 23627-23633 NN denotes HTLV-I
T9294 23634-23642 NNP denotes Proviral
T9295 23643-23647 NNP denotes Load
T9296 23648-23653 IN denotes Since
T9297 23654-23659 NN denotes Foxp3
T9298 23660-23662 VB denotes is
T9299 23663-23672 VB denotes expressed
T9300 23673-23679 RB denotes almost
T9301 23680-23691 RB denotes exclusively
T9302 23692-23698 IN denotes within
T9303 23699-23708 JJ denotes CD4+CD25+
T9304 23709-23710 NN denotes T
T9305 23711-23716 NN denotes cells
T9306 23716-23717 -COMMA- denotes ,
T9307 23718-23719 DT denotes a
T9308 23720-23725 JJ denotes major
T9309 23726-23731 JJ denotes viral
T9310 23732-23741 NN denotes reservoir
T9311 23742-23745 IN denotes for
T9312 23746-23752 NN denotes HTLV-I
T9313 23753-23754 -LRB- denotes [
T9314 23754-23756 CD denotes 33
T9315 23756-23757 -RRB- denotes ]
T9316 23757-23758 -COMMA- denotes ,
T9317 23759-23761 PRP denotes it
T9318 23762-23765 VB denotes was
T9319 23766-23775 JJ denotes important
T9320 23776-23778 TO denotes to
T9321 23779-23788 VB denotes determine
T9322 23789-23796 IN denotes whether
T9323 23797-23802 EX denotes there
T9324 23803-23806 VB denotes was
T9325 23807-23809 DT denotes an
T9326 23810-23821 NN denotes association
T9327 23822-23829 IN denotes between
T9328 23830-23835 NN denotes Foxp3
T9329 23836-23839 CC denotes and
T9330 23840-23846 NN denotes HTLV-I
T9331 23847-23858 NN denotes replication
T9332 23859-23861 IN denotes in
T9333 23862-23870 JJ denotes infected
T9334 23871-23879 NN denotes patients
T9335 23881-23883 PRP denotes We
T9336 23884-23893 RB denotes therefore
T9337 23894-23905 VB denotes quantitated
T9338 23906-23909 DT denotes the
T9339 23910-23915 NN denotes Foxp3
T9340 23916-23923 NN denotes protein
T9341 23924-23934 NN denotes expression
T9342 23935-23937 IN denotes in
T9343 23938-23947 JJ denotes CD4+CD25+
T9344 23948-23949 NN denotes T
T9345 23950-23955 NN denotes cells
T9346 23956-23958 IN denotes by
T9347 23959-23963 NN denotes flow
T9348 23964-23973 NN denotes cytometry
T9349 23974-23977 CC denotes and
T9350 23978-23981 DT denotes the
T9351 23982-23988 NN denotes HTLV-I
T9352 23989-23997 JJ denotes proviral
T9353 23998-24002 NN denotes load
T9354 24003-24004 -LRB- denotes (
T9355 24004-24005 DT denotes a
T9356 24006-24015 JJ denotes surrogate
T9357 24016-24022 NN denotes marker
T9358 24023-24025 IN denotes of
T9359 24026-24031 JJ denotes viral
T9360 24032-24043 NN denotes replication
T9361 24043-24044 -RRB- denotes )
T9362 24045-24047 IN denotes by
T9363 24048-24057 JJ denotes real-time
T9364 24058-24061 NN denotes PCR
T9365 24062-24066 IN denotes from
T9366 24067-24072 CD denotes eight
T9367 24073-24081 NN denotes patients
T9368 24082-24086 IN denotes with
T9369 24087-24094 NN denotes HAM/TSP
T9370 24095-24098 CC denotes and
T9371 24099-24104 CD denotes eight
T9372 24105-24117 JJ denotes asymptomatic
T9373 24118-24126 NN denotes carriers
T9374 24127-24128 -LRB- denotes (
T9375 24128-24131 NN denotes ACs
T9376 24131-24132 -RRB- denotes )
T9377 24134-24137 DT denotes The
T9378 24138-24142 NN denotes data
T9379 24143-24147 IN denotes from
T9380 24148-24152 DT denotes this
T9381 24153-24161 NN denotes analysis
T9382 24162-24164 VB denotes is
T9383 24165-24175 VB denotes summarized
T9384 24176-24178 IN denotes in
T9385 24179-24184 JJ denotes Table
T9386 24185-24186 CD denotes 1
T9387 24188-24190 IN denotes As
T9388 24191-24199 VB denotes expected
T9389 24199-24200 -COMMA- denotes ,
T9390 24201-24209 NN denotes patients
T9391 24210-24214 IN denotes with
T9392 24215-24222 NN denotes HAM/TSP
T9393 24223-24232 VB denotes exhibited
T9394 24233-24246 RB denotes significantly
T9395 24247-24253 JJ denotes higher
T9396 24254-24262 JJ denotes proviral
T9397 24263-24268 NN denotes loads
T9398 24269-24270 -LRB- denotes (
T9399 24270-24279 VB denotes indicated
T9400 24280-24282 IN denotes as
T9401 24283-24289 NN denotes HTLV-I
T9402 24290-24298 JJ denotes proviral
T9403 24299-24302 NN denotes DNA
T9404 24303-24313 NN denotes copies/100
T9405 24314-24319 NN denotes cells
T9406 24319-24320 -RRB- denotes )
T9407 24321-24322 -LRB- denotes (
T9408 24322-24327 CD denotes 34.68
T9409 24328-24329 CC denotes ±
T9410 24330-24335 CD denotes 23.19
T9411 24335-24336 -RRB- denotes )
T9412 24337-24345 VB denotes compared
T9413 24346-24348 TO denotes to
T9414 24349-24352 NN denotes ACs
T9415 24353-24354 -LRB- denotes (
T9416 24354-24358 CD denotes 4.75
T9417 24359-24360 CC denotes ±
T9418 24361-24365 CD denotes 5.47
T9419 24365-24366 -RRB- denotes )
T9420 24367-24368 -LRB- denotes (
T9421 24368-24369 NN denotes p
T9422 24370-24371 SYM denotes =
T9423 24372-24378 CD denotes 0.0008
T9424 24378-24379 -RRB- denotes )
T9425 24381-24384 DT denotes The
T9426 24385-24395 NN denotes percentage
T9427 24396-24398 IN denotes of
T9428 24399-24405 JJ denotes Foxp3+
T9429 24406-24411 NN denotes cells
T9430 24412-24418 IN denotes within
T9431 24419-24422 DT denotes the
T9432 24423-24432 JJ denotes CD4+CD25+
T9433 24433-24434 NN denotes T
T9434 24435-24439 NN denotes cell
T9435 24440-24450 NN denotes population
T9436 24451-24454 VB denotes was
T9437 24455-24468 RB denotes significantly
T9438 24469-24476 JJ denotes greater
T9439 24477-24479 IN denotes in
T9440 24480-24483 NN denotes ACs
T9441 24484-24485 -LRB- denotes (
T9442 24485-24490 CD denotes 43.23
T9443 24491-24492 CC denotes ±
T9444 24493-24498 CD denotes 12.95
T9445 24498-24499 -RRB- denotes )
T9446 24500-24504 IN denotes than
T9447 24505-24507 IN denotes in
T9448 24508-24515 NN denotes HAM/TSP
T9449 24516-24524 NN denotes patients
T9450 24525-24526 -LRB- denotes (
T9451 24526-24531 CD denotes 18.59
T9452 24532-24533 CC denotes ±
T9453 24534-24538 CD denotes 5.77
T9454 24538-24539 -RRB- denotes )
T9455 24540-24541 -LRB- denotes (
T9456 24541-24542 NN denotes p
T9457 24543-24544 SYM denotes =
T9458 24545-24551 CD denotes 0.0033
T9459 24551-24552 -RRB- denotes )
T9460 24554-24559 DT denotes These
T9461 24560-24564 NN denotes data
T9462 24565-24572 VB denotes suggest
T9463 24573-24577 IN denotes that
T9464 24578-24582 JJ denotes high
T9465 24583-24589 NN denotes levels
T9466 24590-24592 IN denotes of
T9467 24593-24598 NN denotes Foxp3
T9468 24599-24606 NN denotes protein
T9469 24607-24617 NN denotes expression
T9470 24618-24621 VB denotes are
T9471 24622-24632 VB denotes associated
T9472 24633-24637 IN denotes with
T9473 24638-24645 VB denotes reduced
T9474 24646-24652 NN denotes HTLV-I
T9475 24653-24664 NN denotes replication
T9476 24665-24667 FW denotes in
T9477 24668-24672 FW denotes vivo
T9478 24674-24678 PRP denotes They
T9479 24679-24683 RB denotes also
T9480 24684-24691 VB denotes support
T9481 24692-24695 PRP-DOLLAR- denotes our
T9482 24696-24702 JJ denotes recent
T9483 24703-24710 NN denotes reports
T9484 24711-24715 IN denotes that
T9485 24716-24720 JJ denotes high
T9486 24721-24729 JJ denotes proviral
T9487 24730-24735 NN denotes loads
T9488 24735-24736 -COMMA- denotes ,
T9489 24737-24742 WDT denotes which
T9490 24743-24747 VB denotes have
T9491 24748-24752 VB denotes been
T9492 24753-24758 VB denotes shown
T9493 24759-24761 TO denotes to
T9494 24762-24771 VB denotes correlate
T9495 24772-24776 IN denotes with
T9496 24777-24781 JJ denotes high
T9497 24782-24785 NN denotes Tax
T9498 24786-24790 NN denotes mRNA
T9499 24791-24793 IN denotes in
T9500 24794-24809 JJ denotes HTLV-I-infected
T9501 24810-24818 NN denotes patients
T9502 24818-24819 -COMMA- denotes ,
T9503 24820-24823 VB denotes are
T9504 24824-24834 VB denotes associated
T9505 24835-24839 IN denotes with
T9506 24840-24847 VB denotes reduced
T9507 24848-24853 NN denotes Foxp3
T9508 24854-24864 NN denotes expression
T9509 24865-24866 -LRB- denotes [
T9510 24866-24870 CD denotes 8,34
T9511 24870-24871 -RRB- denotes ]
T10638 24952-24956 NN denotes CREB
T10639 24957-24959 VB denotes Is
T10640 24960-24961 DT denotes a
T10641 24962-24968 NN denotes Target
T10642 24969-24972 IN denotes for
T10643 24973-24988 JJ denotes Transcriptional
T10644 24989-24999 NNP denotes Repression
T10645 25000-25002 IN denotes by
T10646 25003-25008 NN denotes Foxp3
T10647 25009-25017 IN denotes Although
T10648 25018-25023 NN denotes Foxp3
T10649 25024-25029 MD denotes could
T10650 25030-25043 VB denotes down-regulate
T10651 25044-25057 JJ denotes Tax-dependent
T10652 25058-25073 NN denotes transactivation
T10653 25074-25076 IN denotes of
T10654 25077-25080 DT denotes the
T10655 25081-25087 NN denotes HTLV-I
T10656 25088-25091 NN denotes LTR
T10657 25092-25093 -LRB- denotes (
T10658 25093-25099 NN denotes Figure
T10659 25100-25102 NN denotes 4B
T10660 25102-25103 -RRB- denotes )
T10661 25104-25107 CC denotes and
T10662 25108-25115 VB denotes inhibit
T10663 25116-25119 NN denotes Tax
T10664 25120-25130 NN denotes expression
T10665 25131-25135 IN denotes from
T10666 25136-25138 DT denotes an
T10667 25139-25149 JJ denotes infectious
T10668 25150-25159 JJ denotes molecular
T10669 25160-25165 NN denotes clone
T10670 25166-25167 -LRB- denotes (
T10671 25167-25173 NN denotes Figure
T10672 25174-25175 CD denotes 5
T10673 25175-25176 -RRB- denotes )
T10674 25176-25177 -COMMA- denotes ,
T10675 25178-25183 NN denotes Foxp3
T10676 25184-25190 VB denotes failed
T10677 25191-25193 TO denotes to
T10678 25194-25202 VB denotes modulate
T10679 25203-25206 NN denotes Tax
T10680 25207-25215 NN denotes function
T10681 25216-25218 IN denotes in
T10682 25219-25222 DT denotes the
T10683 25223-25230 NN denotes absence
T10684 25231-25233 IN denotes of
T10685 25234-25237 DT denotes the
T10686 25238-25243 JJ denotes viral
T10687 25244-25252 NN denotes promoter
T10688 25253-25254 -LRB- denotes (
T10689 25254-25260 NN denotes Figure
T10690 25261-25263 NN denotes 4D
T10691 25263-25264 -RRB- denotes )
T10692 25266-25271 DT denotes These
T10693 25272-25279 NN denotes results
T10694 25280-25283 VB denotes led
T10695 25284-25286 PRP denotes us
T10696 25287-25289 TO denotes to
T10697 25290-25301 VB denotes hypothesize
T10698 25302-25306 IN denotes that
T10699 25307-25312 NN denotes Foxp3
T10700 25313-25317 VB denotes acts
T10701 25318-25320 IN denotes on
T10702 25321-25327 NN denotes HTLV-I
T10703 25328-25332 NN denotes gene
T10704 25333-25343 NN denotes expression
T10705 25344-25346 IN denotes by
T10706 25347-25358 VB denotes interacting
T10707 25359-25363 IN denotes with
T10708 25364-25372 NN denotes proteins
T10709 25373-25382 JJ denotes important
T10710 25383-25386 IN denotes for
T10711 25387-25394 VB denotes driving
T10712 25395-25401 NN denotes HTLV-I
T10713 25402-25405 NN denotes LTR
T10714 25406-25414 NN denotes activity
T10715 25415-25417 FW denotes in
T10716 25418-25422 FW denotes vivo
T10717 25424-25432 JJ denotes Previous
T10718 25433-25440 NN denotes studies
T10719 25441-25445 VB denotes have
T10720 25446-25458 VB denotes demonstrated
T10721 25459-25463 IN denotes that
T10722 25464-25467 DT denotes the
T10723 25468-25482 JJ denotes Tax-responsive
T10724 25483-25491 NN denotes elements
T10725 25492-25498 IN denotes within
T10726 25499-25502 DT denotes the
T10727 25503-25509 NN denotes HTLV-I
T10728 25510-25513 NN denotes LTR
T10729 25514-25518 VB denotes play
T10730 25519-25520 DT denotes a
T10731 25521-25528 JJ denotes crucial
T10732 25529-25533 NN denotes role
T10733 25534-25536 IN denotes in
T10734 25537-25544 VB denotes driving
T10735 25545-25557 JJ denotes Tax-mediated
T10736 25558-25573 NN denotes transactivation
T10737 25574-25576 IN denotes of
T10738 25577-25580 DT denotes the
T10739 25581-25587 NN denotes HTLV-I
T10740 25588-25591 NN denotes LTR
T10741 25592-25593 -LRB- denotes [
T10742 25593-25595 CD denotes 18
T10743 25595-25596 -RRB- denotes ]
T10744 25598-25601 DT denotes The
T10745 25602-25616 JJ denotes Tax-responsive
T10746 25617-25625 NN denotes elements
T10747 25626-25630 VB denotes have
T10748 25631-25635 VB denotes been
T10749 25636-25641 VB denotes shown
T10750 25642-25644 TO denotes to
T10751 25645-25653 VB denotes resemble
T10752 25654-25658 NN denotes CREB
T10753 25659-25666 NN denotes binding
T10754 25667-25672 NN denotes sites
T10755 25672-25673 -COMMA- denotes ,
T10756 25674-25678 VB denotes bind
T10757 25679-25683 NN denotes CREB
T10758 25684-25686 FW denotes in
T10759 25687-25692 FW denotes vitro
T10760 25693-25696 CC denotes and
T10761 25697-25699 FW denotes in
T10762 25700-25704 FW denotes vivo
T10763 25704-25705 -COMMA- denotes ,
T10764 25706-25709 CC denotes and
T10765 25710-25720 VB denotes facilitate
T10766 25721-25727 NN denotes HTLV-I
T10767 25728-25731 NN denotes LTR
T10768 25732-25742 NN denotes activation
T10769 25743-25747 CC denotes both
T10770 25748-25750 IN denotes in
T10771 25751-25754 DT denotes the
T10772 25755-25763 NN denotes presence
T10773 25764-25767 CC denotes and
T10774 25768-25770 IN denotes in
T10775 25771-25774 DT denotes the
T10776 25775-25782 NN denotes absence
T10777 25783-25785 IN denotes of
T10778 25786-25789 NN denotes Tax
T10779 25790-25791 -LRB- denotes [
T10780 25791-25796 CD denotes 35,36
T10781 25796-25797 -RRB- denotes ]
T10782 25799-25804 VB denotes Ching
T10783 25805-25808 CC denotes and
T10784 25809-25819 NN denotes colleagues
T10785 25820-25821 -LRB- denotes [
T10786 25821-25823 CD denotes 18
T10787 25823-25824 -RRB- denotes ]
T10788 25825-25837 VB denotes demonstrated
T10789 25838-25842 IN denotes that
T10790 25843-25851 NN denotes addition
T10791 25852-25854 IN denotes of
T10792 25855-25856 DT denotes a
T10793 25857-25874 JJ denotes dominant-negative
T10794 25875-25879 NN denotes CREB
T10795 25880-25890 NN denotes expression
T10796 25891-25897 NN denotes vector
T10797 25898-25906 VB denotes resulted
T10798 25907-25909 IN denotes in
T10799 25910-25916 RB denotes nearly
T10800 25917-25925 JJ denotes complete
T10801 25926-25936 NN denotes inhibition
T10802 25937-25939 IN denotes of
T10803 25940-25952 JJ denotes Tax-mediated
T10804 25953-25963 NN denotes activation
T10805 25964-25966 IN denotes of
T10806 25967-25970 DT denotes the
T10807 25971-25977 NN denotes HTLV-I
T10808 25978-25981 NN denotes LTR
T10809 25981-25982 -COMMA- denotes ,
T10810 25983-25988 IN denotes while
T10811 25989-25997 VB denotes blocking
T10812 25998-26003 NN denotes NF-κB
T10813 26004-26014 NN denotes activation
T10814 26015-26017 IN denotes by
T10815 26018-26026 NN denotes addition
T10816 26027-26029 IN denotes of
T10817 26030-26031 DT denotes a
T10818 26032-26049 JJ denotes dominant-negative
T10819 26050-26054 NN denotes IKKβ
T10820 26055-26065 NN denotes expression
T10821 26066-26072 NN denotes vector
T10822 26073-26076 VB denotes had
T10823 26077-26079 DT denotes no
T10824 26080-26086 NN denotes effect
T10825 26087-26089 IN denotes on
T10826 26090-26093 NN denotes Tax
T10827 26094-26109 NN denotes transactivation
T10828 26110-26112 IN denotes of
T10829 26113-26116 DT denotes the
T10830 26117-26123 NN denotes HTLV-I
T10831 26124-26127 NN denotes LTR
T10832 26129-26138 RB denotes Therefore
T10833 26138-26139 -COMMA- denotes ,
T10834 26140-26142 PRP denotes we
T10835 26143-26155 VB denotes hypothesized
T10836 26156-26160 IN denotes that
T10837 26161-26166 NN denotes Foxp3
T10838 26167-26170 MD denotes may
T10839 26171-26178 VB denotes inhibit
T10840 26179-26182 NN denotes Tax
T10841 26183-26198 NN denotes transactivation
T10842 26199-26201 IN denotes of
T10843 26202-26205 DT denotes the
T10844 26206-26212 NN denotes HTLV-I
T10845 26213-26216 NN denotes LTR
T10846 26217-26220 IN denotes via
T10847 26221-26231 NN denotes disruption
T10848 26232-26234 IN denotes of
T10849 26235-26238 DT denotes the
T10850 26239-26243 NN denotes CREB
T10851 26244-26253 NN denotes signaling
T10852 26254-26261 NN denotes pathway
T10853 26263-26265 TO denotes To
T10854 26266-26270 VB denotes test
T10855 26271-26275 DT denotes this
T10856 26276-26287 NN denotes possibility
T10857 26287-26288 -COMMA- denotes ,
T10858 26289-26292 NN denotes HEK
T10859 26293-26297 NN denotes 293T
T10860 26298-26303 NN denotes cells
T10861 26304-26308 VB denotes were
T10862 26309-26320 VB denotes transfected
T10863 26321-26325 IN denotes with
T10864 26326-26328 DT denotes an
T10865 26329-26335 NN denotes HTLV-I
T10866 26336-26339 NN denotes LTR
T10867 26340-26342 CC denotes or
T10868 26343-26352 JJ denotes synthetic
T10869 26353-26357 NN denotes CREB
T10870 26358-26366 NN denotes reporter
T10871 26367-26373 NN denotes vector
T10872 26374-26379 IN denotes along
T10873 26380-26384 IN denotes with
T10874 26385-26386 DT denotes a
T10875 26387-26394 NN denotes control
T10876 26395-26405 NN denotes expression
T10877 26406-26412 NN denotes vector
T10878 26413-26414 -LRB- denotes (
T10879 26414-26418 NN denotes EGFP
T10880 26418-26419 -RRB- denotes )
T10881 26420-26422 CC denotes or
T10882 26423-26433 NN denotes expression
T10883 26434-26441 NN denotes vectors
T10884 26442-26450 VB denotes encoding
T10885 26451-26456 CD denotes Foxp3
T10886 26457-26459 CC denotes or
T10887 26460-26464 NN denotes ΔFKH
T10888 26466-26468 IN denotes As
T10889 26469-26474 VB denotes shown
T10890 26475-26477 IN denotes in
T10891 26478-26484 NN denotes Figure
T10892 26485-26487 NN denotes 6A
T10893 26487-26488 -COMMA- denotes ,
T10894 26489-26494 NN denotes Foxp3
T10895 26495-26509 VB denotes down-regulated
T10896 26510-26515 JJ denotes basal
T10897 26516-26526 NN denotes activation
T10898 26527-26529 IN denotes of
T10899 26530-26533 DT denotes the
T10900 26534-26540 NN denotes HTLV-I
T10901 26541-26544 NN denotes LTR
T10902 26545-26548 CC denotes and
T10903 26549-26562 NN denotes transcription
T10904 26563-26565 IN denotes of
T10905 26566-26567 DT denotes a
T10906 26568-26577 JJ denotes synthetic
T10907 26578-26582 NN denotes CREB
T10908 26583-26591 NN denotes reporter
T10909 26592-26598 NN denotes vector
T10910 26598-26599 -COMMA- denotes ,
T10911 26600-26610 VB denotes suggesting
T10912 26611-26615 IN denotes that
T10913 26616-26621 NN denotes Foxp3
T10914 26622-26636 VB denotes down-regulates
T10915 26637-26643 NN denotes HTLV-I
T10916 26644-26647 NN denotes LTR
T10917 26648-26658 NN denotes activation
T10918 26659-26661 IN denotes by
T10919 26662-26671 VB denotes targeting
T10920 26672-26675 DT denotes the
T10921 26676-26680 NN denotes CREB
T10922 26681-26688 NN denotes pathway
T10923 26690-26698 NN denotes Deletion
T10924 26699-26701 IN denotes of
T10925 26702-26705 DT denotes the
T10926 26706-26709 NN denotes FKH
T10927 26710-26716 NN denotes domain
T10928 26717-26719 IN denotes of
T10929 26720-26725 NN denotes Foxp3
T10930 26726-26734 VB denotes dampened
T10931 26735-26738 DT denotes the
T10932 26739-26750 JJ denotes suppressive
T10933 26751-26757 NN denotes effect
T10934 26758-26760 IN denotes of
T10935 26761-26766 NN denotes Foxp3
T10936 26766-26767 -COMMA- denotes ,
T10937 26768-26771 CC denotes but
T10938 26772-26775 VB denotes did
T10939 26776-26779 RB denotes not
T10940 26780-26790 RB denotes completely
T10941 26791-26799 VB denotes abrogate
T10942 26800-26811 NN denotes suppression
T10943 26811-26812 -COMMA- denotes ,
T10944 26813-26815 IN denotes as
T10945 26816-26818 VB denotes is
T10946 26819-26823 VB denotes seen
T10947 26824-26828 IN denotes with
T10948 26829-26845 JJ denotes NF-κB-responsive
T10949 26846-26855 NN denotes promoters
T10950 26856-26858 IN denotes in
T10951 26859-26862 NN denotes HEK
T10952 26863-26867 NN denotes 293T
T10953 26868-26873 NN denotes cells
T10954 26875-26879 IN denotes Like
T10955 26880-26885 NN denotes NF-κB
T10956 26886-26896 NN denotes activation
T10957 26896-26897 -COMMA- denotes ,
T10958 26898-26902 NN denotes CREB
T10959 26903-26918 JJ denotes transcriptional
T10960 26919-26929 NN denotes activation
T10961 26930-26933 VB denotes was
T10962 26934-26938 RB denotes also
T10963 26939-26949 VB denotes suppressed
T10964 26950-26952 IN denotes by
T10965 26953-26963 NN denotes expression
T10966 26964-26966 IN denotes of
T10967 26967-26972 NN denotes Foxp3
T10968 26972-26973 -COMMA- denotes ,
T10969 26974-26977 CC denotes and
T10970 26978-26980 TO denotes to
T10971 26981-26982 DT denotes a
T10972 26983-26990 JJ denotes similar
T10973 26991-26997 NN denotes extent
T10974 26998-27002 NN denotes ΔFKH
T10975 27002-27003 -COMMA- denotes ,
T10976 27004-27006 IN denotes in
T10977 27007-27014 JJ denotes healthy
T10978 27015-27020 NN denotes donor
T10979 27021-27025 JJ denotes CD4+
T10980 27026-27027 NN denotes T
T10981 27028-27033 NN denotes cells
T10982 27034-27035 -LRB- denotes (
T10983 27035-27041 NN denotes Figure
T10984 27042-27044 NN denotes 6B
T10985 27044-27045 -RRB- denotes )
T10986 27047-27056 RB denotes Similarly
T10987 27056-27057 -COMMA- denotes ,
T10988 27058-27063 NN denotes Foxp3
T10989 27064-27067 CC denotes and
T10990 27068-27072 NN denotes ΔFKH
T10991 27073-27077 RB denotes also
T10992 27078-27087 VB denotes repressed
T10993 27088-27093 JJ denotes basal
T10994 27094-27100 NN denotes HTLV-I
T10995 27101-27104 NN denotes LTR
T10996 27105-27115 NN denotes activation
T10997 27116-27118 IN denotes in
T10998 27119-27126 JJ denotes primary
T10999 27127-27132 JJ denotes human
T11000 27133-27137 JJ denotes CD4+
T11001 27138-27139 NN denotes T
T11002 27140-27145 NN denotes cells
T11003 27146-27147 -LRB- denotes (
T11004 27147-27153 NN denotes Figure
T11005 27154-27156 NN denotes 6C
T11006 27156-27157 -RRB- denotes )
T11007 27159-27161 TO denotes To
T11008 27162-27165 PRP-DOLLAR- denotes our
T11009 27166-27175 NN denotes knowledge
T11010 27175-27176 -COMMA- denotes ,
T11011 27177-27181 DT denotes this
T11012 27182-27184 VB denotes is
T11013 27185-27188 DT denotes the
T11014 27189-27194 JJ denotes first
T11015 27195-27203 NN denotes evidence
T11016 27204-27215 VB denotes implicating
T11017 27216-27220 NN denotes CREB
T11018 27221-27223 IN denotes as
T11019 27224-27225 DT denotes a
T11020 27226-27235 JJ denotes molecular
T11021 27236-27242 NN denotes target
T11022 27243-27245 IN denotes of
T11023 27246-27251 NN denotes Foxp3
T11024 27253-27255 IN denotes As
T11025 27256-27264 VB denotes observed
T11026 27265-27269 IN denotes with
T11027 27270-27275 NN denotes NF-κB
T11028 27276-27286 NN denotes activation
T11029 27286-27287 -COMMA- denotes ,
T11030 27288-27292 NN denotes ΔFKH
T11031 27293-27296 VB denotes was
T11032 27297-27298 DT denotes a
T11033 27299-27303 RB denotes more
T11034 27304-27310 JJ denotes potent
T11035 27311-27320 NN denotes inhibitor
T11036 27321-27323 IN denotes of
T11037 27324-27328 NN denotes CREB
T11038 27329-27339 NN denotes activation
T11039 27340-27342 IN denotes in
T11040 27343-27347 JJ denotes CD4+
T11041 27348-27349 NN denotes T
T11042 27350-27355 NN denotes cells
T11043 27356-27360 IN denotes than
T11044 27361-27363 IN denotes in
T11045 27364-27367 NN denotes HEK
T11046 27368-27372 NN denotes 293T
T11047 27373-27378 NN denotes cells
T11048 27378-27379 -COMMA- denotes ,
T11049 27380-27387 RB denotes further
T11050 27388-27398 VB denotes indicating
T11051 27399-27403 IN denotes that
T11052 27404-27405 DT denotes a
T11053 27406-27410 NN denotes cell
T11054 27411-27424 JJ denotes type-specific
T11055 27425-27434 NN denotes mechanism
T11056 27435-27437 IN denotes of
T11057 27438-27444 NN denotes action
T11058 27445-27448 MD denotes may
T11059 27449-27455 VB denotes govern
T11060 27456-27459 DT denotes the
T11061 27460-27468 NN denotes function
T11062 27469-27471 IN denotes of
T11063 27472-27476 DT denotes this
T11064 27477-27482 NN denotes Foxp3
T11065 27483-27489 NN denotes mutant
T11066 29170-29172 TO denotes To
T11067 29173-29182 VB denotes determine
T11068 29183-29190 IN denotes whether
T11069 29191-29196 CD denotes Foxp3
T11070 29197-29207 VB denotes functioned
T11071 29208-29210 IN denotes by
T11072 29211-29219 RB denotes directly
T11073 29220-29229 VB denotes signaling
T11074 29230-29237 IN denotes through
T11075 29238-29242 NN denotes CREB
T11076 29242-29243 -COMMA- denotes ,
T11077 29244-29246 PRP denotes we
T11078 29247-29255 VB denotes utilized
T11079 29256-29266 NN denotes expression
T11080 29267-29274 NN denotes vectors
T11081 29275-29283 VB denotes encoding
T11082 29284-29290 NN denotes CREB-1
T11083 29291-29293 CC denotes or
T11084 29294-29299 NN denotes c-Jun
T11085 29300-29301 -LRB- denotes (
T11086 29301-29302 DT denotes a
T11087 29303-29309 NN denotes member
T11088 29310-29312 IN denotes of
T11089 29313-29316 DT denotes the
T11090 29317-29326 NN denotes activator
T11091 29327-29334 NN denotes protein
T11092 29335-29336 CD denotes 1
T11093 29337-29343 NN denotes family
T11094 29344-29346 IN denotes of
T11095 29347-29360 NN denotes transcription
T11096 29361-29368 NN denotes factors
T11097 29368-29369 -RRB- denotes )
T11098 29370-29375 VB denotes fused
T11099 29376-29384 JJ denotes in-frame
T11100 29385-29387 TO denotes to
T11101 29388-29391 DT denotes the
T11102 29392-29399 NN denotes Gal4-BD
T11103 29400-29401 -LRB- denotes (
T11104 29401-29415 NN denotes Gal4-BD-CREB-1
T11105 29416-29419 CC denotes and
T11106 29420-29433 NN denotes Gal4-BD-c-Jun
T11107 29433-29434 -RRB- denotes )
T11108 29436-29438 IN denotes As
T11109 29439-29444 VB denotes shown
T11110 29445-29447 IN denotes in
T11111 29448-29454 NN denotes Figure
T11112 29455-29457 NN denotes 6D
T11113 29457-29458 -COMMA- denotes ,
T11114 29459-29469 NN denotes activation
T11115 29470-29472 IN denotes of
T11116 29473-29474 DT denotes a
T11117 29475-29490 JJ denotes Gal4-responsive
T11118 29491-29499 NN denotes reporter
T11119 29500-29506 NN denotes vector
T11120 29507-29509 IN denotes by
T11121 29510-29524 NN denotes Gal4-BD-CREB-1
T11122 29525-29528 VB denotes was
T11123 29529-29543 VB denotes down-regulated
T11124 29544-29546 IN denotes by
T11125 29547-29552 NN denotes Foxp3
T11126 29553-29561 VB denotes compared
T11127 29562-29564 TO denotes to
T11128 29565-29572 NN denotes control
T11129 29573-29579 NN denotes vector
T11130 29580-29581 -LRB- denotes (
T11131 29581-29585 NN denotes EGFP
T11132 29585-29586 -RRB- denotes )
T11133 29586-29587 -COMMA- denotes ,
T11134 29588-29598 VB denotes indicating
T11135 29599-29603 IN denotes that
T11136 29604-29609 CD denotes Foxp3
T11137 29610-29619 NN denotes functions
T11138 29620-29622 IN denotes by
T11139 29623-29631 RB denotes directly
T11140 29632-29634 CC denotes or
T11141 29635-29645 RB denotes indirectly
T11142 29646-29657 VB denotes interacting
T11143 29658-29662 IN denotes with
T11144 29663-29669 NN denotes CREB-1
T11145 29671-29678 RB denotes However
T11146 29678-29679 -COMMA- denotes ,
T11147 29680-29685 NN denotes Foxp3
T11148 29686-29692 VB denotes failed
T11149 29693-29695 TO denotes to
T11150 29696-29704 RB denotes markedly
T11151 29705-29711 VB denotes affect
T11152 29712-29727 JJ denotes transcriptional
T11153 29728-29738 NN denotes activation
T11154 29739-29741 IN denotes of
T11155 29742-29755 NN denotes Gal4-BD-c-Jun
T11156 29756-29757 -LRB- denotes (
T11157 29757-29762 NN denotes c-Jun
T11158 29763-29766 VB denotes has
T11159 29767-29771 RB denotes also
T11160 29772-29776 VB denotes been
T11161 29777-29789 VB denotes demonstrated
T11162 29790-29792 TO denotes to
T11163 29793-29797 VB denotes bind
T11164 29798-29800 TO denotes to
T11165 29801-29804 DT denotes the
T11166 29805-29811 NN denotes HTLV-I
T11167 29812-29815 NN denotes LTR
T11168 29815-29816 -RRB- denotes )
T11169 29817-29820 CC denotes and
T11170 29821-29832 NN denotes Gal4-BD-Tax
T11171 29833-29834 -LRB- denotes (
T11172 29834-29837 VB denotes see
T11173 29838-29844 NNP denotes Figure
T11174 29845-29846 CD denotes 5
T11175 29846-29847 -RRB- denotes )
T11176 29849-29860 RB denotes Importantly
T11177 29860-29861 -COMMA- denotes ,
T11178 29862-29865 DT denotes the
T11179 29866-29875 NN denotes mechanism
T11180 29876-29878 IN denotes of
T11181 29879-29893 JJ denotes Foxp3-mediated
T11182 29894-29904 NN denotes inhibition
T11183 29905-29907 IN denotes of
T11184 29908-29922 JJ denotes CREB-dependent
T11185 29923-29936 NN denotes transcription
T11186 29937-29940 VB denotes was
T11187 29941-29944 RB denotes not
T11188 29945-29948 JJ denotes due
T11189 29949-29951 TO denotes to
T11190 29952-29953 DT denotes a
T11191 29954-29959 NN denotes block
T11192 29960-29962 IN denotes in
T11193 29963-29969 NN denotes CREB-1
T11194 29970-29977 NN denotes protein
T11195 29978-29988 NN denotes expression
T11196 29988-29989 -COMMA- denotes ,
T11197 29990-29992 IN denotes as
T11198 29993-30003 VB denotes determined
T11199 30004-30006 IN denotes by
T11200 30007-30014 JJ denotes Western
T11201 30015-30019 NN denotes blot
T11202 30020-30028 NN denotes analysis
T11203 30029-30030 -LRB- denotes (
T11204 30030-30036 NN denotes Figure
T11205 30037-30039 NN denotes 6E
T11206 30039-30040 -RRB- denotes )
T11207 30042-30050 IN denotes Although
T11208 30051-30056 DT denotes these
T11209 30057-30064 NN denotes results
T11210 30065-30076 VB denotes demonstrate
T11211 30077-30081 IN denotes that
T11212 30082-30087 NN denotes Foxp3
T11213 30088-30097 VB denotes functions
T11214 30098-30100 IN denotes as
T11215 30101-30102 DT denotes a
T11216 30103-30115 NN denotes co-repressor
T11217 30116-30118 IN denotes of
T11218 30119-30123 NN denotes CREB
T11219 30124-30134 NN denotes activation
T11220 30135-30136 -LRB- denotes (
T11221 30136-30138 IN denotes in
T11222 30139-30147 NN denotes addition
T11223 30148-30150 TO denotes to
T11224 30151-30156 NN denotes NF-κB
T11225 30157-30160 CC denotes and
T11226 30161-30166 NN denotes NF-AT
T11227 30166-30167 -RRB- denotes )
T11228 30167-30168 -COMMA- denotes ,
T11229 30169-30171 PRP denotes we
T11230 30172-30176 VB denotes were
T11231 30177-30183 JJ denotes unable
T11232 30184-30186 TO denotes to
T11233 30187-30193 VB denotes detect
T11234 30194-30195 DT denotes a
T11235 30196-30202 JJ denotes direct
T11236 30203-30211 JJ denotes physical
T11237 30212-30223 NN denotes interaction
T11238 30224-30231 IN denotes between
T11239 30232-30238 NN denotes CREB-1
T11240 30239-30242 CC denotes and
T11241 30243-30248 NN denotes Foxp3
T11242 30249-30251 IN denotes by
T11243 30252-30273 NN denotes coimmunoprecipitation
T11244 30274-30276 CC denotes or
T11245 30277-30286 JJ denotes mammalian
T11246 30287-30297 JJ denotes two-hybrid
T11247 30298-30306 NN denotes analysis
T11248 30307-30308 -LRB- denotes (
T11249 30308-30319 JJ denotes unpublished
T11250 30320-30324 NN denotes data
T11251 30324-30325 -RRB- denotes )
T11252 30327-30336 RB denotes Therefore
T11253 30336-30337 -COMMA- denotes ,
T11254 30338-30341 PRP-DOLLAR- denotes our
T11255 30342-30346 NN denotes data
T11256 30347-30354 VB denotes suggest
T11257 30355-30359 IN denotes that
T11258 30360-30365 NN denotes Foxp3
T11259 30366-30369 MD denotes may
T11260 30370-30379 VB denotes interfere
T11261 30380-30384 IN denotes with
T11262 30385-30389 NN denotes CREB
T11263 30390-30399 NN denotes signaling
T11264 30400-30402 IN denotes at
T11265 30403-30405 DT denotes an
T11266 30406-30414 JJ denotes upstream
T11267 30415-30420 NN denotes event
T11268 30420-30421 -COMMA- denotes ,
T11269 30422-30426 JJ denotes such
T11270 30427-30429 IN denotes as
T11271 30430-30445 NN denotes phosphorylation
T11272 30446-30448 IN denotes of
T11273 30449-30453 NN denotes CREB
T11274 30454-30456 CC denotes or
T11275 30457-30477 NN denotes recruitment/function
T11276 30478-30480 IN denotes of
T11277 30481-30492 NN denotes coactivator
T11278 30493-30501 NN denotes proteins
T11279 30502-30514 JJ denotes CREB-binding
T11280 30515-30522 NN denotes protein
T11281 30523-30524 -LRB- denotes (
T11282 30524-30527 NN denotes CBP
T11283 30527-30528 -RRB- denotes )
T11284 30528-30533 CD denotes /p300
T12825 30536-30541 CD denotes Foxp3
T12826 30542-30553 VB denotes Antagonizes
T12827 30554-30558 NN denotes CREB
T12828 30559-30574 JJ denotes Transcriptional
T12829 30575-30585 NN denotes Activation
T12830 30586-30588 IN denotes by
T12831 30589-30599 NNP denotes Disrupting
T12832 30600-30611 NNP denotes Coactivator
T12833 30612-30623 NNP denotes Recruitment
T12834 30624-30635 NN denotes Stimulation
T12835 30636-30638 IN denotes of
T12836 30639-30653 JJ denotes CREB-dependent
T12837 30654-30667 NN denotes transcription
T12838 30668-30670 IN denotes by
T12839 30671-30679 NN denotes reagents
T12840 30680-30684 WDT denotes that
T12841 30685-30693 VB denotes activate
T12842 30694-30703 NN denotes adenylate
T12843 30704-30711 NN denotes cyclase
T12844 30712-30715 CC denotes and
T12845 30716-30724 VB denotes increase
T12846 30725-30729 NN denotes cAMP
T12847 30730-30736 NN denotes levels
T12848 30737-30738 -LRB- denotes (
T12849 30738-30742 FW denotes e.g.
T12850 30742-30743 -COMMA- denotes ,
T12851 30744-30753 NN denotes forskolin
T12852 30753-30754 -RRB- denotes )
T12853 30755-30763 VB denotes increase
T12854 30764-30767 DT denotes the
T12855 30768-30783 NN denotes transactivation
T12856 30784-30793 NN denotes potential
T12857 30794-30796 IN denotes of
T12858 30797-30801 NN denotes CREB
T12859 30802-30809 IN denotes through
T12860 30810-30825 NN denotes phosphorylation
T12861 30826-30828 IN denotes of
T12862 30829-30835 NN denotes serine
T12863 30836-30839 CD denotes 133
T12864 30840-30842 IN denotes by
T12865 30843-30850 NN denotes protein
T12866 30851-30857 NN denotes kinase
T12867 30858-30859 NN denotes A
T12868 30859-30860 -COMMA- denotes ,
T12869 30861-30866 WDT denotes which
T12870 30867-30874 VB denotes permits
T12871 30875-30882 NN denotes binding
T12872 30883-30886 CC denotes and
T12873 30887-30898 NN denotes recruitment
T12874 30899-30901 IN denotes of
T12875 30902-30914 NN denotes coactivators
T12876 30915-30923 NN denotes CBP/p300
T12877 30924-30926 TO denotes to
T12878 30927-30930 DT denotes the
T12879 30931-30939 NN denotes promoter
T12880 30940-30941 -LRB- denotes [
T12881 30941-30946 CD denotes 37,38
T12882 30946-30947 -RRB- denotes ]
T12883 30949-30964 NN denotes Phosphorylation
T12884 30965-30967 IN denotes of
T12885 30968-30974 NN denotes serine
T12886 30975-30978 CD denotes 133
T12887 30979-30983 VB denotes does
T12888 30984-30987 RB denotes not
T12889 30987-30988 -COMMA- denotes ,
T12890 30989-30996 RB denotes however
T12891 30996-30997 -COMMA- denotes ,
T12892 30998-31004 VB denotes affect
T12893 31005-31008 DT denotes the
T12894 31009-31020 JJ denotes DNA-binding
T12895 31021-31029 NN denotes activity
T12896 31030-31032 IN denotes of
T12897 31033-31037 NN denotes CREB
T12898 31038-31040 IN denotes in
T12899 31041-31045 JJ denotes most
T12900 31046-31051 NN denotes cases
T12901 31052-31053 -LRB- denotes [
T12902 31053-31058 CD denotes 39–41
T12903 31058-31059 -RRB- denotes ]
T12904 31061-31069 NN denotes Addition
T12905 31070-31072 IN denotes of
T12906 31073-31082 NN denotes forskolin
T12907 31083-31085 TO denotes to
T12908 31086-31089 NN denotes HEK
T12909 31090-31094 NN denotes 293T
T12910 31095-31100 NN denotes cells
T12911 31101-31111 VB denotes stimulated
T12912 31112-31122 NN denotes activation
T12913 31123-31125 IN denotes of
T12914 31126-31127 DT denotes a
T12915 31128-31132 NN denotes CREB
T12916 31133-31141 NN denotes reporter
T12917 31142-31148 NN denotes vector
T12918 31149-31154 IN denotes about
T12919 31155-31157 CD denotes 65
T12920 31158-31162 JJ denotes fold
T12921 31163-31164 -LRB- denotes (
T12922 31164-31170 NN denotes Figure
T12923 31171-31173 NN denotes 7A
T12924 31173-31174 -RRB- denotes )
T12925 31176-31190 NN denotes Overexpression
T12926 31191-31193 IN denotes of
T12927 31194-31199 NN denotes Foxp3
T12928 31200-31203 VB denotes was
T12929 31204-31211 JJ denotes capable
T12930 31212-31214 IN denotes of
T12931 31215-31230 VB denotes down-regulating
T12932 31231-31248 JJ denotes forskolin-induced
T12933 31249-31253 NN denotes CREB
T12934 31254-31269 JJ denotes transcriptional
T12935 31270-31280 NN denotes activation
T12936 31282-31285 DT denotes The
T12937 31286-31296 JJ denotes functional
T12938 31297-31308 NN denotes interaction
T12939 31309-31316 IN denotes between
T12940 31317-31322 NN denotes Foxp3
T12941 31323-31326 CC denotes and
T12942 31327-31331 NN denotes CREB
T12943 31332-31335 VB denotes did
T12944 31336-31339 RB denotes not
T12945 31340-31346 VB denotes affect
T12946 31347-31350 DT denotes the
T12947 31351-31362 JJ denotes DNA-binding
T12948 31363-31371 NN denotes activity
T12949 31372-31374 IN denotes of
T12950 31375-31381 NN denotes CREB-1
T12951 31381-31382 -COMMA- denotes ,
T12952 31383-31386 CC denotes but
T12953 31387-31390 VB denotes did
T12954 31391-31395 VB denotes show
T12955 31396-31397 DT denotes a
T12956 31398-31404 JJ denotes modest
T12957 31405-31413 NN denotes decrease
T12958 31414-31416 IN denotes in
T12959 31417-31427 VB denotes activating
T12960 31428-31441 NN denotes transcription
T12961 31442-31448 NN denotes factor
T12962 31449-31450 CD denotes 2
T12963 31451-31452 -LRB- denotes (
T12964 31452-31457 NN denotes ATF-2
T12965 31457-31458 -RRB- denotes )
T12966 31459-31470 JJ denotes DNA-binding
T12967 31471-31479 NN denotes activity
T12968 31480-31482 IN denotes in
T12969 31483-31486 DT denotes the
T12970 31487-31495 NN denotes presence
T12971 31496-31498 IN denotes of
T12972 31499-31508 NN denotes forskolin
T12973 31509-31511 IN denotes as
T12974 31512-31522 VB denotes determined
T12975 31523-31525 IN denotes by
T12976 31526-31539 NN denotes transcription
T12977 31540-31546 NN denotes factor
T12978 31547-31552 NN denotes ELISA
T12979 31553-31554 -LRB- denotes (
T12980 31554-31560 NN denotes Figure
T12981 31561-31563 NN denotes 7B
T12982 31563-31564 -RRB- denotes )
T12983 32999-33004 IN denotes While
T12984 33005-33010 NN denotes Foxp3
T12985 33011-33014 VB denotes has
T12986 33015-33019 VB denotes been
T12987 33020-33025 VB denotes shown
T12988 33026-33028 TO denotes to
T12989 33029-33033 VB denotes bind
T12990 33034-33036 TO denotes to
T12991 33037-33040 CC denotes and
T12992 33041-33048 VB denotes repress
T12993 33049-33059 NN denotes activation
T12994 33060-33062 IN denotes of
T12995 33063-33067 CC denotes both
T12996 33068-33073 NN denotes NF-κB
T12997 33074-33077 CC denotes and
T12998 33078-33083 NN denotes NF-AT
T12999 33083-33084 -COMMA- denotes ,
T13000 33085-33092 RB denotes exactly
T13001 33093-33096 WRB denotes how
T13002 33097-33102 NN denotes Foxp3
T13003 33103-33112 NN denotes functions
T13004 33113-33115 TO denotes to
T13005 33116-33121 VB denotes bring
T13006 33122-33127 RP denotes about
T13007 33128-33132 DT denotes this
T13008 33133-33139 NN denotes affect
T13009 33140-33143 VB denotes has
T13010 33144-33147 RB denotes not
T13011 33148-33152 VB denotes been
T13012 33153-33163 VB denotes elucidated
T13013 33165-33167 TO denotes To
T13014 33168-33177 VB denotes determine
T13015 33178-33181 WRB denotes how
T13016 33182-33187 NN denotes Foxp3
T13017 33188-33194 VB denotes blocks
T13018 33195-33209 JJ denotes CREB-dependent
T13019 33210-33223 NN denotes transcription
T13020 33223-33224 -COMMA- denotes ,
T13021 33225-33227 PRP denotes we
T13022 33228-33236 VB denotes examined
T13023 33237-33244 IN denotes whether
T13024 33245-33250 NN denotes Foxp3
T13025 33251-33254 VB denotes was
T13026 33255-33262 JJ denotes capable
T13027 33263-33265 IN denotes of
T13028 33266-33267 -LRB- denotes (
T13029 33267-33268 CD denotes 1
T13030 33268-33269 -RRB- denotes )
T13031 33270-33280 VB denotes disrupting
T13032 33281-33284 DT denotes the
T13033 33285-33296 NN denotes recruitment
T13034 33297-33299 IN denotes of
T13035 33300-33311 NN denotes coactivator
T13036 33312-33320 NN denotes proteins
T13037 33321-33327 CC denotes and/or
T13038 33328-33329 -LRB- denotes (
T13039 33329-33330 LS denotes 2
T13040 33330-33331 -RRB- denotes )
T13041 33332-33342 VB denotes preventing
T13042 33343-33358 NN denotes phosphorylation
T13043 33359-33361 IN denotes of
T13044 33362-33366 NN denotes CREB
T13045 33367-33369 IN denotes at
T13046 33370-33376 NN denotes serine
T13047 33377-33380 CD denotes 133
T13048 33381-33382 -LRB- denotes (
T13049 33382-33387 WDT denotes which
T13050 33388-33390 VB denotes is
T13051 33391-33392 DT denotes a
T13052 33393-33405 NN denotes prerequisite
T13053 33406-33409 IN denotes for
T13054 33410-33421 NN denotes coactivator
T13055 33422-33433 NN denotes recruitment
T13056 33433-33434 -RRB- denotes )
T13057 33436-33441 IN denotes Since
T13058 33442-33446 DT denotes both
T13059 33447-33449 IN denotes of
T13060 33450-33455 DT denotes these
T13061 33456-33462 NN denotes events
T13062 33463-33466 VB denotes are
T13063 33467-33475 VB denotes required
T13064 33476-33479 IN denotes for
T13065 33480-33494 JJ denotes CREB-dependent
T13066 33495-33499 NN denotes gene
T13067 33500-33510 NN denotes expression
T13068 33510-33511 -COMMA- denotes ,
T13069 33512-33514 PRP denotes we
T13070 33515-33527 VB denotes hypothesized
T13071 33528-33532 IN denotes that
T13072 33533-33538 NN denotes Foxp3
T13073 33539-33542 MD denotes may
T13074 33543-33549 VB denotes affect
T13075 33550-33554 NN denotes CREB
T13076 33555-33565 NN denotes activation
T13077 33566-33568 IN denotes at
T13078 33569-33573 DT denotes both
T13079 33574-33579 NN denotes steps
T13080 33581-33583 TO denotes To
T13081 33584-33593 VB denotes determine
T13082 33594-33601 IN denotes whether
T13083 33602-33607 NN denotes Foxp3
T13084 33608-33611 MD denotes can
T13085 33612-33619 VB denotes disrupt
T13086 33620-33623 DT denotes the
T13087 33624-33644 NN denotes function/recruitment
T13088 33645-33647 IN denotes of
T13089 33648-33651 DT denotes the
T13090 33652-33663 NN denotes coactivator
T13091 33664-33671 NN denotes protein
T13092 33672-33676 NN denotes p300
T13093 33676-33677 -COMMA- denotes ,
T13094 33678-33680 PRP denotes we
T13095 33681-33691 VB denotes introduced
T13096 33692-33693 DT denotes a
T13097 33694-33698 NN denotes Gal4
T13098 33699-33707 NN denotes reporter
T13099 33708-33714 NN denotes vector
T13100 33715-33718 CC denotes and
T13101 33719-33720 DT denotes a
T13102 33721-33735 NN denotes Gal4-BD-CREB-1
T13103 33736-33746 NN denotes expression
T13104 33747-33753 NN denotes vector
T13105 33754-33758 IN denotes into
T13106 33759-33762 NN denotes HEK
T13107 33763-33767 NN denotes 293T
T13108 33768-33773 NN denotes cells
T13109 33774-33776 IN denotes in
T13110 33777-33780 DT denotes the
T13111 33781-33788 NN denotes absence
T13112 33789-33791 CC denotes or
T13113 33792-33800 NN denotes presence
T13114 33801-33803 IN denotes of
T13115 33804-33809 NN denotes Foxp3
T13116 33809-33810 -COMMA- denotes ,
T13117 33811-33815 NN denotes p300
T13118 33815-33816 -COMMA- denotes ,
T13119 33817-33823 CC denotes and/or
T13120 33824-33831 NN denotes control
T13121 33832-33842 NN denotes expression
T13122 33843-33850 NN denotes vectors
T13123 33851-33852 -LRB- denotes (
T13124 33852-33858 NN denotes Figure
T13125 33859-33861 NN denotes 7C
T13126 33861-33862 -RRB- denotes )
T13127 33864-33866 IN denotes As
T13128 33867-33875 VB denotes expected
T13129 33875-33876 -COMMA- denotes ,
T13130 33877-33881 NN denotes p300
T13131 33882-33896 NN denotes overexpression
T13132 33897-33907 VB denotes stimulated
T13133 33908-33921 NN denotes transcription
T13134 33922-33924 IN denotes of
T13135 33925-33928 DT denotes the
T13136 33929-33943 NN denotes Gal4-BD-CREB-1
T13137 33944-33950 NN denotes fusion
T13138 33951-33958 NN denotes protein
T13139 33960-33965 CD denotes Foxp3
T13140 33965-33966 -COMMA- denotes ,
T13141 33967-33972 RB denotes again
T13142 33972-33973 -COMMA- denotes ,
T13143 33974-33983 VB denotes repressed
T13144 33984-33989 JJ denotes basal
T13145 33990-33996 NN denotes levels
T13146 33997-33999 IN denotes of
T13147 34000-34014 NN denotes Gal4-BD-CREB-1
T13148 34015-34025 NN denotes activation
T13149 34026-34028 IN denotes by
T13150 34029-34033 JJ denotes more
T13151 34034-34038 IN denotes than
T13152 34039-34045 RB denotes 2-fold
T13153 34045-34046 -COMMA- denotes ,
T13154 34047-34052 IN denotes while
T13155 34053-34064 RB denotes effectively
T13156 34065-34077 VB denotes neutralizing
T13157 34078-34092 NN denotes Gal4-BD-CREB-1
T13158 34093-34103 NN denotes activation
T13159 34104-34106 IN denotes in
T13160 34107-34110 DT denotes the
T13161 34111-34119 NN denotes presence
T13162 34120-34122 IN denotes of
T13163 34123-34127 NN denotes p300
T13164 34129-34131 PRP denotes We
T13165 34132-34136 RB denotes next
T13166 34137-34145 VB denotes analyzed
T13167 34146-34149 DT denotes the
T13168 34150-34156 NN denotes effect
T13169 34157-34159 IN denotes of
T13170 34160-34165 NN denotes Foxp3
T13171 34166-34168 IN denotes on
T13172 34169-34184 NN denotes phosphorylation
T13173 34185-34187 IN denotes of
T13174 34188-34192 NN denotes CREB
T13175 34193-34195 IN denotes at
T13176 34196-34202 NN denotes serine
T13177 34203-34206 CD denotes 133
T13178 34207-34209 IN denotes in
T13179 34210-34227 JJ denotes forskolin-treated
T13180 34228-34231 NN denotes HEK
T13181 34232-34236 NN denotes 293T
T13182 34237-34242 NN denotes cells
T13183 34243-34245 IN denotes by
T13184 34246-34253 JJ denotes Western
T13185 34254-34258 NN denotes blot
T13186 34259-34267 NN denotes analysis
T13187 34269-34283 NN denotes Overexpression
T13188 34284-34286 IN denotes of
T13189 34287-34292 NN denotes Foxp3
T13190 34293-34299 VB denotes failed
T13191 34300-34302 TO denotes to
T13192 34303-34309 VB denotes reduce
T13193 34310-34313 DT denotes the
T13194 34314-34324 JJ denotes detectable
T13195 34325-34331 NN denotes levels
T13196 34332-34334 IN denotes of
T13197 34335-34339 NN denotes CREB
T13198 34340-34355 NN denotes phosphorylation
T13199 34356-34361 VB denotes using
T13200 34362-34363 DT denotes a
T13201 34364-34379 JJ denotes phosphospecific
T13202 34380-34388 NN denotes antibody
T13203 34389-34392 IN denotes for
T13204 34393-34399 NN denotes CREB-1
T13205 34400-34401 -LRB- denotes (
T13206 34401-34412 JJ denotes unpublished
T13207 34413-34417 NN denotes data
T13208 34417-34418 -RRB- denotes )
T13209 34420-34427 RB denotes However
T13210 34427-34428 -COMMA- denotes ,
T13211 34429-34433 WRB denotes when
T13212 34434-34436 PRP denotes we
T13213 34437-34446 VB denotes attempted
T13214 34447-34449 TO denotes to
T13215 34450-34459 VB denotes determine
T13216 34460-34467 IN denotes whether
T13217 34468-34473 NN denotes Foxp3
T13218 34474-34479 MD denotes could
T13219 34480-34490 RB denotes physically
T13220 34491-34499 VB denotes interact
T13221 34500-34504 IN denotes with
T13222 34505-34508 DT denotes the
T13223 34509-34520 NN denotes coactivator
T13224 34521-34528 NN denotes protein
T13225 34529-34533 NN denotes p300
T13226 34533-34534 -COMMA- denotes ,
T13227 34535-34537 PRP denotes we
T13228 34538-34543 VB denotes found
T13229 34544-34548 IN denotes that
T13230 34549-34553 NN denotes p300
T13231 34554-34572 VB denotes immunoprecipitated
T13232 34573-34578 CD denotes Foxp3
T13233 34579-34583 WRB denotes when
T13234 34584-34588 DT denotes both
T13235 34589-34597 NN denotes proteins
T13236 34598-34602 VB denotes were
T13237 34603-34616 VB denotes overexpressed
T13238 34617-34619 IN denotes in
T13239 34620-34623 NN denotes HEK
T13240 34624-34628 NN denotes 293T
T13241 34629-34634 NN denotes cells
T13242 34635-34636 -LRB- denotes (
T13243 34636-34642 NN denotes Figure
T13244 34643-34645 NN denotes 7D
T13245 34645-34646 -RRB- denotes )
T13246 34648-34660 RB denotes Collectively
T13247 34660-34661 -COMMA- denotes ,
T13248 34662-34667 DT denotes these
T13249 34668-34675 NN denotes results
T13250 34676-34683 VB denotes suggest
T13251 34684-34688 IN denotes that
T13252 34689-34694 NN denotes Foxp3
T13253 34695-34706 VB denotes antagonizes
T13254 34707-34721 JJ denotes CREB-dependent
T13255 34722-34726 NN denotes gene
T13256 34727-34737 NN denotes expression
T13257 34738-34740 IN denotes by
T13258 34741-34749 RB denotes directly
T13259 34750-34761 VB denotes interacting
T13260 34762-34766 IN denotes with
T13261 34767-34778 NN denotes coactivator
T13262 34779-34783 NN denotes p300
T13263 34784-34787 CC denotes and
T13264 34788-34799 VB denotes interfering
T13265 34800-34804 IN denotes with
T13266 34805-34808 PRP-DOLLAR- denotes its
T13267 34809-34817 NN denotes function
T13268 34818-34824 CC denotes and/or
T13269 34825-34836 NN denotes recruitment
T13270 34837-34839 TO denotes to
T13271 34840-34855 JJ denotes CREB-responsive
T13272 34856-34864 NN denotes promoter
T13273 34865-34874 NN denotes sequences
T15976 34888-34890 IN denotes In
T15977 34891-34894 DT denotes the
T15978 34895-34902 JJ denotes present
T15979 34903-34908 NN denotes study
T15980 34908-34909 -COMMA- denotes ,
T15981 34910-34912 PRP denotes we
T15982 34913-34917 VB denotes show
T15983 34918-34922 IN denotes that
T15984 34923-34928 NN denotes Foxp3
T15985 34929-34938 VB denotes functions
T15986 34939-34941 IN denotes as
T15987 34942-34943 DT denotes a
T15988 34944-34950 JJ denotes potent
T15989 34951-34960 NN denotes repressor
T15990 34961-34963 IN denotes of
T15991 34964-34970 NN denotes NF-κB-
T15992 34971-34974 CC denotes and
T15993 34975-34989 JJ denotes CREB-dependent
T15994 34990-35005 JJ denotes transcriptional
T15995 35006-35016 NN denotes activation
T15996 35018-35029 RB denotes Furthermore
T15997 35029-35030 -COMMA- denotes ,
T15998 35031-35034 DT denotes the
T15999 35035-35052 JJ denotes carboxyl-terminal
T16000 35053-35056 NN denotes FKH
T16001 35057-35063 NN denotes domain
T16002 35064-35071 VB denotes appears
T16003 35072-35074 TO denotes to
T16004 35075-35077 VB denotes be
T16005 35078-35089 JJ denotes dispensable
T16006 35090-35093 IN denotes for
T16007 35094-35103 VB denotes mediating
T16008 35104-35109 DT denotes these
T16009 35110-35117 NN denotes effects
T16010 35117-35118 -COMMA- denotes ,
T16011 35119-35121 IN denotes at
T16012 35122-35127 JJ denotes least
T16013 35128-35130 IN denotes in
T16014 35131-35132 NN denotes T
T16015 35133-35137 NN denotes cell
T16016 35138-35149 NN denotes populations
T16017 35151-35155 DT denotes This
T16018 35156-35167 NN denotes observation
T16019 35168-35171 MD denotes may
T16020 35172-35178 VB denotes become
T16021 35179-35188 JJ denotes important
T16022 35189-35191 IN denotes in
T16023 35192-35197 NN denotes light
T16024 35198-35200 IN denotes of
T16025 35201-35207 JJ denotes recent
T16026 35208-35215 NN denotes reports
T16027 35216-35226 VB denotes suggesting
T16028 35227-35231 IN denotes that
T16029 35232-35237 NN denotes Foxp3
T16030 35238-35248 NN denotes expression
T16031 35249-35251 IN denotes in
T16032 35252-35258 JJ denotes thymic
T16033 35259-35269 JJ denotes epithelial
T16034 35270-35275 NN denotes cells
T16035 35276-35279 VB denotes was
T16036 35280-35287 JJ denotes crucial
T16037 35288-35291 IN denotes for
T16038 35292-35301 VB denotes directing
T16039 35302-35313 NN denotes development
T16040 35314-35316 IN denotes of
T16041 35317-35318 NN denotes T
T16042 35319-35324 NN denotes cells
T16043 35325-35327 IN denotes in
T16044 35328-35331 DT denotes the
T16045 35332-35338 NN denotes thymus
T16046 35339-35340 -LRB- denotes [
T16047 35340-35342 CD denotes 42
T16048 35342-35343 -RRB- denotes ]
T16049 35345-35358 RB denotes Interestingly
T16050 35358-35359 -COMMA- denotes ,
T16051 35360-35363 DT denotes the
T16052 35364-35372 NN denotes majority
T16053 35373-35375 IN denotes of
T16054 35376-35379 DT denotes the
T16055 35380-35387 JJ denotes genetic
T16056 35388-35397 NN denotes mutations
T16057 35398-35408 VB denotes associated
T16058 35409-35413 IN denotes with
T16059 35414-35418 NN denotes IPEX
T16060 35418-35419 -COMMA- denotes ,
T16061 35420-35421 DT denotes a
T16062 35422-35428 JJ denotes severe
T16063 35429-35439 JJ denotes autoimmune
T16064 35440-35448 NN denotes disorder
T16065 35449-35455 VB denotes caused
T16066 35456-35458 IN denotes by
T16067 35459-35469 JJ denotes functional
T16068 35470-35482 NN denotes inactivation
T16069 35483-35485 IN denotes of
T16070 35486-35491 NN denotes Foxp3
T16071 35491-35492 -COMMA- denotes ,
T16072 35493-35496 NN denotes map
T16073 35497-35499 TO denotes to
T16074 35500-35503 DT denotes the
T16075 35504-35521 JJ denotes carboxyl-terminal
T16076 35522-35525 NN denotes FKH
T16077 35526-35532 NN denotes domain
T16078 35533-35535 CC denotes or
T16079 35536-35539 DT denotes the
T16080 35540-35547 NN denotes leucine
T16081 35548-35554 NN denotes zipper
T16082 35555-35561 NN denotes domain
T16083 35562-35564 IN denotes in
T16084 35565-35568 DT denotes the
T16085 35569-35576 JJ denotes central
T16086 35577-35583 NN denotes region
T16087 35584-35586 IN denotes of
T16088 35587-35590 DT denotes the
T16089 35591-35598 NN denotes protein
T16090 35600-35604 RB denotes Only
T16091 35605-35608 CD denotes one
T16092 35609-35617 NN denotes mutation
T16093 35618-35628 VB denotes associated
T16094 35629-35633 IN denotes with
T16095 35634-35638 NN denotes IPEX
T16096 35639-35641 TO denotes to
T16097 35642-35646 NN denotes date
T16098 35647-35650 VB denotes has
T16099 35651-35655 VB denotes been
T16100 35656-35662 VB denotes mapped
T16101 35663-35665 TO denotes to
T16102 35666-35669 DT denotes the
T16103 35670-35684 JJ denotes amino-terminal
T16104 35685-35697 JJ denotes proline-rich
T16105 35698-35704 NN denotes region
T16106 35705-35706 -LRB- denotes [
T16107 35706-35708 CD denotes 43
T16108 35708-35709 -RRB- denotes ]
T16109 35711-35713 PRP denotes It
T16110 35714-35716 VB denotes is
T16111 35717-35725 JJ denotes possible
T16112 35726-35730 IN denotes that
T16113 35731-35734 DT denotes the
T16114 35735-35738 NN denotes FKH
T16115 35739-35745 NN denotes domain
T16116 35746-35749 VB denotes has
T16117 35750-35751 DT denotes a
T16118 35752-35759 JJ denotes complex
T16119 35760-35768 JJ denotes tertiary
T16120 35769-35778 NN denotes structure
T16121 35779-35783 WDT denotes that
T16122 35784-35786 VB denotes is
T16123 35787-35799 RB denotes particularly
T16124 35800-35809 JJ denotes sensitive
T16125 35810-35812 TO denotes to
T16126 35813-35823 NN denotes misfolding
T16127 35824-35830 VB denotes caused
T16128 35831-35833 IN denotes by
T16129 35834-35841 JJ denotes genetic
T16130 35842-35851 NN denotes mutations
T16131 35852-35855 CC denotes and
T16132 35856-35860 IN denotes that
T16133 35861-35863 DT denotes an
T16134 35864-35870 JJ denotes intact
T16135 35871-35874 NN denotes FKH
T16136 35875-35881 NN denotes domain
T16137 35882-35884 VB denotes is
T16138 35885-35895 RB denotes absolutely
T16139 35896-35904 JJ denotes critical
T16140 35905-35908 IN denotes for
T16141 35909-35918 VB denotes promoting
T16142 35919-35924 NN denotes Foxp3
T16143 35925-35933 NN denotes function
T16144 35934-35936 IN denotes in
T16145 35937-35940 DT denotes the
T16146 35941-35948 NN denotes nucleus
T16147 35948-35949 -COMMA- denotes ,
T16148 35950-35957 IN denotes whereas
T16149 35958-35961 DT denotes the
T16150 35962-35971 NN denotes structure
T16151 35972-35974 IN denotes of
T16152 35975-35978 DT denotes the
T16153 35979-35993 JJ denotes amino-terminal
T16154 35994-36006 JJ denotes proline-rich
T16155 36007-36013 NN denotes region
T16156 36014-36017 MD denotes may
T16157 36018-36026 VB denotes tolerate
T16158 36027-36034 JJ denotes certain
T16159 36035-36044 NN denotes mutations
T16160 36045-36047 RB denotes as
T16161 36048-36052 RB denotes long
T16162 36053-36055 IN denotes as
T16163 36056-36059 DT denotes the
T16164 36060-36071 NN denotes NF-κB/NF-AT
T16165 36072-36079 NN denotes binding
T16166 36080-36085 NN denotes motif
T16167 36086-36093 VB denotes remains
T16168 36094-36103 JJ denotes unaltered
T16169 36105-36109 DT denotes This
T16170 36110-36115 NN denotes motif
T16171 36116-36119 MD denotes may
T16172 36120-36124 RB denotes also
T16173 36125-36132 VB denotes include
T16174 36133-36136 DT denotes the
T16175 36137-36141 NN denotes zinc
T16176 36142-36148 NN denotes finger
T16177 36149-36155 NN denotes domain
T16178 36157-36158 DT denotes A
T16179 36159-36166 JJ denotes logical
T16180 36167-36173 NN denotes region
T16181 36174-36178 WDT denotes that
T16182 36179-36182 MD denotes may
T16183 36183-36185 VB denotes be
T16184 36186-36194 VB denotes targeted
T16185 36195-36197 IN denotes by
T16186 36198-36201 DT denotes the
T16187 36202-36216 JJ denotes amino-terminal
T16188 36217-36229 JJ denotes proline-rich
T16189 36230-36236 NN denotes region
T16190 36237-36239 IN denotes of
T16191 36240-36245 NN denotes Foxp3
T16192 36246-36248 VB denotes is
T16193 36249-36252 DT denotes the
T16194 36253-36256 NN denotes Rel
T16195 36257-36265 NN denotes homology
T16196 36266-36272 NN denotes domain
T16197 36273-36278 VB denotes found
T16198 36279-36281 IN denotes in
T16199 36282-36286 CC denotes both
T16200 36287-36292 NN denotes NF-κB
T16201 36293-36296 CC denotes and
T16202 36297-36302 NN denotes NF-AT
T16203 36303-36309 NN denotes family
T16204 36310-36318 NN denotes proteins
T16205 36320-36321 DT denotes A
T16206 36322-36328 NN denotes region
T16207 36329-36333 WDT denotes that
T16208 36334-36337 MD denotes may
T16209 36338-36342 RB denotes also
T16210 36343-36345 VB denotes be
T16211 36346-36355 JJ denotes important
T16212 36356-36360 IN denotes with
T16213 36361-36368 NN denotes respect
T16214 36369-36371 TO denotes to
T16215 36372-36377 CD denotes Foxp3
T16216 36378-36386 NN denotes function
T16217 36387-36389 VB denotes is
T16218 36390-36393 DT denotes the
T16219 36394-36401 NN denotes leucine
T16220 36402-36408 NN denotes zipper
T16221 36409-36415 NN denotes domain
T16222 36415-36416 -COMMA- denotes ,
T16223 36417-36419 IN denotes as
T16224 36420-36432 VB denotes demonstrated
T16225 36433-36435 IN denotes by
T16226 36436-36439 DT denotes the
T16227 36440-36446 NN denotes number
T16228 36447-36449 IN denotes of
T16229 36450-36459 NN denotes mutations
T16230 36460-36470 VB denotes associated
T16231 36471-36475 IN denotes with
T16232 36476-36480 NN denotes IPEX
T16233 36481-36485 WDT denotes that
T16234 36486-36490 VB denotes have
T16235 36491-36495 VB denotes been
T16236 36496-36502 VB denotes mapped
T16237 36503-36505 IN denotes in
T16238 36506-36510 DT denotes this
T16239 36511-36517 NN denotes region
T16240 36518-36520 IN denotes of
T16241 36521-36526 NN denotes Foxp3
T16242 36528-36531 DT denotes The
T16243 36532-36536 NN denotes role
T16244 36537-36539 IN denotes of
T16245 36540-36544 DT denotes this
T16246 36545-36551 NN denotes domain
T16247 36552-36554 IN denotes in
T16248 36555-36560 NN denotes Foxp3
T16249 36561-36569 NN denotes function
T16250 36570-36577 VB denotes remains
T16251 36578-36593 JJ denotes uncharacterized
T16252 36593-36594 -COMMA- denotes ,
T16253 36595-36598 CC denotes but
T16254 36599-36602 MD denotes may
T16255 36603-36607 VB denotes play
T16256 36608-36609 DT denotes a
T16257 36610-36614 NN denotes role
T16258 36615-36617 IN denotes in
T16259 36618-36623 NN denotes dimer
T16260 36624-36633 NN denotes formation
T16261 36634-36636 IN denotes as
T16262 36637-36639 PRP denotes it
T16263 36640-36644 VB denotes does
T16264 36645-36647 IN denotes in
T16265 36648-36653 JJ denotes other
T16266 36654-36658 NN denotes Foxp
T16267 36659-36665 NN denotes family
T16268 36666-36673 NN denotes members
T16269 36674-36675 -LRB- denotes [
T16270 36675-36677 CD denotes 44
T16271 36677-36678 -RRB- denotes ]
T16272 36680-36687 IN denotes Because
T16273 36688-36691 DT denotes the
T16274 36692-36704 NN denotes pathogenesis
T16275 36705-36707 IN denotes of
T16276 36708-36709 DT denotes a
T16277 36710-36716 NN denotes number
T16278 36717-36719 IN denotes of
T16279 36720-36738 JJ denotes retroviral-induced
T16280 36739-36750 JJ denotes immunologic
T16281 36751-36760 NN denotes disorders
T16282 36761-36765 JJ denotes such
T16283 36766-36768 IN denotes as
T16284 36769-36779 NN denotes HIV-1/AIDS
T16285 36780-36783 CC denotes and
T16286 36784-36798 NN denotes HTLV-I/HAM/TSP
T16287 36799-36803 VB denotes have
T16288 36804-36808 VB denotes been
T16289 36809-36819 VB denotes associated
T16290 36820-36824 IN denotes with
T16291 36825-36838 NN denotes dysregulation
T16292 36839-36841 IN denotes of
T16293 36842-36847 NN denotes Foxp3
T16294 36848-36858 NN denotes expression
T16295 36859-36860 -LRB- denotes [
T16296 36860-36864 CD denotes 8,45
T16297 36864-36865 -RRB- denotes ]
T16298 36865-36866 -COMMA- denotes ,
T16299 36867-36869 PRP denotes we
T16300 36870-36874 RB denotes also
T16301 36875-36883 VB denotes examined
T16302 36884-36887 DT denotes the
T16303 36888-36892 NN denotes role
T16304 36893-36895 IN denotes of
T16305 36896-36901 NN denotes Foxp3
T16306 36902-36904 IN denotes in
T16307 36905-36915 JJ denotes retroviral
T16308 36916-36920 NN denotes gene
T16309 36921-36931 NN denotes expression
T16310 36933-36938 NN denotes HIV-1
T16311 36939-36942 NN denotes LTR
T16312 36943-36953 NN denotes activation
T16313 36954-36956 IN denotes in
T16314 36957-36961 JJ denotes CD4+
T16315 36962-36963 NN denotes T
T16316 36964-36969 NN denotes cells
T16317 36970-36972 VB denotes is
T16318 36973-36983 RB denotes critically
T16319 36984-36993 JJ denotes dependent
T16320 36994-36996 IN denotes on
T16321 36997-37000 CD denotes two
T16322 37001-37007 JJ denotes tandem
T16323 37008-37013 NN denotes NF-κB
T16324 37014-37019 NN denotes sites
T16325 37020-37027 JJ denotes located
T16326 37028-37035 IN denotes between
T16327 37036-37046 NN denotes nucleotide
T16328 37047-37056 NN denotes positions
T16329 37057-37061 CD denotes −102
T16330 37062-37065 CC denotes and
T16331 37066-37069 NN denotes −81
T16332 37070-37076 IN denotes within
T16333 37077-37080 DT denotes the
T16334 37081-37086 NN denotes HIV-1
T16335 37087-37095 NN denotes enhancer
T16336 37096-37102 NN denotes region
T16337 37102-37103 -COMMA- denotes ,
T16338 37104-37111 IN denotes whereas
T16339 37112-37118 NN denotes HTLV-I
T16340 37119-37122 NN denotes LTR
T16341 37123-37133 NN denotes activation
T16342 37134-37136 IN denotes in
T16343 37137-37140 DT denotes the
T16344 37141-37149 NN denotes presence
T16345 37150-37152 CC denotes or
T16346 37153-37160 NN denotes absence
T16347 37161-37163 IN denotes of
T16348 37164-37167 DT denotes the
T16349 37168-37182 JJ denotes HTLV-I-encoded
T16350 37183-37197 NN denotes transactivator
T16351 37198-37205 NN denotes protein
T16352 37206-37209 NN denotes Tax
T16353 37210-37212 VB denotes is
T16354 37213-37224 JJ denotes independent
T16355 37225-37227 IN denotes of
T16356 37228-37233 NN denotes NF-κB
T16357 37234-37235 -LRB- denotes [
T16358 37235-37237 CD denotes 18
T16359 37237-37238 -RRB- denotes ]
T16360 37240-37242 TO denotes To
T16361 37243-37246 PRP-DOLLAR- denotes our
T16362 37247-37256 NN denotes knowledge
T16363 37257-37260 IN denotes for
T16364 37261-37264 DT denotes the
T16365 37265-37270 JJ denotes first
T16366 37271-37275 NN denotes time
T16367 37275-37276 -COMMA- denotes ,
T16368 37277-37282 NN denotes Foxp3
T16369 37283-37286 VB denotes was
T16370 37287-37292 VB denotes shown
T16371 37293-37295 TO denotes to
T16372 37296-37300 VB denotes have
T16373 37301-37302 DT denotes a
T16374 37303-37309 JJ denotes direct
T16375 37310-37316 NN denotes effect
T16376 37317-37319 IN denotes on
T16377 37320-37325 NN denotes HIV-1
T16378 37326-37329 NN denotes LTR
T16379 37330-37343 NN denotes transcription
T16380 37345-37353 NN denotes Deletion
T16381 37354-37356 IN denotes of
T16382 37357-37360 DT denotes the
T16383 37361-37366 NN denotes NF-κB
T16384 37367-37372 NN denotes sites
T16385 37373-37379 IN denotes within
T16386 37380-37383 DT denotes the
T16387 37384-37389 NN denotes HIV-1
T16388 37390-37398 NN denotes enhancer
T16389 37399-37405 NN denotes region
T16390 37406-37413 VB denotes reduced
T16391 37414-37417 DT denotes the
T16392 37418-37432 NN denotes responsiveness
T16393 37433-37435 IN denotes of
T16394 37436-37439 DT denotes the
T16395 37440-37445 NN denotes HIV-1
T16396 37446-37449 NN denotes LTR
T16397 37450-37452 TO denotes to
T16398 37453-37467 JJ denotes Foxp3-mediated
T16399 37468-37479 NN denotes suppression
T16400 37481-37483 IN denotes In
T16401 37484-37492 NN denotes addition
T16402 37492-37493 -COMMA- denotes ,
T16403 37494-37497 DT denotes the
T16404 37498-37501 NN denotes FKH
T16405 37502-37508 NN denotes domain
T16406 37509-37511 IN denotes of
T16407 37512-37517 NN denotes Foxp3
T16408 37518-37521 VB denotes was
T16409 37522-37530 VB denotes required
T16410 37531-37534 IN denotes for
T16411 37535-37539 DT denotes this
T16412 37540-37550 JJ denotes inhibitory
T16413 37551-37557 NN denotes effect
T16414 37558-37560 IN denotes in
T16415 37561-37564 NN denotes HEK
T16416 37565-37569 NN denotes 293T
T16417 37570-37575 NN denotes cells
T16418 37575-37576 -COMMA- denotes ,
T16419 37577-37580 CC denotes but
T16420 37581-37584 RB denotes not
T16421 37585-37587 IN denotes in
T16422 37588-37594 NN denotes Jurkat
T16423 37595-37596 NN denotes T
T16424 37597-37602 NN denotes cells
T16425 37602-37603 -COMMA- denotes ,
T16426 37604-37611 JJ denotes similar
T16427 37612-37614 TO denotes to
T16428 37615-37629 JJ denotes Foxp3-mediated
T16429 37630-37641 NN denotes suppression
T16430 37642-37644 IN denotes of
T16431 37645-37646 DT denotes a
T16432 37647-37656 JJ denotes synthetic
T16433 37657-37662 NN denotes NF-κB
T16434 37663-37671 NN denotes reporter
T16435 37673-37676 DT denotes The
T16436 37677-37683 JJ denotes direct
T16437 37684-37690 NN denotes effect
T16438 37691-37693 IN denotes of
T16439 37694-37699 NN denotes Foxp3
T16440 37700-37715 VB denotes down-regulating
T16441 37716-37721 NN denotes HIV-1
T16442 37722-37726 NN denotes gene
T16443 37727-37737 NN denotes expression
T16444 37738-37748 VB denotes correlates
T16445 37749-37753 RB denotes well
T16446 37754-37758 IN denotes with
T16447 37759-37767 RB denotes recently
T16448 37768-37776 VB denotes reported
T16449 37777-37785 NN denotes evidence
T16450 37786-37796 VB denotes indicating
T16451 37797-37801 IN denotes that
T16452 37802-37808 JJ denotes higher
T16453 37809-37819 JJ denotes regulatory
T16454 37820-37828 NN denotes activity
T16455 37829-37831 IN denotes of
T16456 37832-37841 JJ denotes CD4+CD25+
T16457 37842-37843 NN denotes T
T16458 37844-37849 NN denotes cells
T16459 37850-37854 IN denotes from
T16460 37855-37869 JJ denotes HIV-1-infected
T16461 37870-37878 NN denotes patients
T16462 37879-37882 VB denotes was
T16463 37883-37893 VB denotes associated
T16464 37894-37898 IN denotes with
T16465 37899-37904 JJ denotes lower
T16466 37905-37910 NN denotes HIV-1
T16467 37911-37916 JJ denotes viral
T16468 37917-37922 NN denotes loads
T16469 37923-37925 IN denotes in
T16470 37926-37931 DT denotes these
T16471 37932-37940 NN denotes patients
T16472 37941-37942 -LRB- denotes [
T16473 37942-37944 CD denotes 46
T16474 37944-37945 -RRB- denotes ]
T16475 37947-37952 NN denotes Foxp3
T16476 37953-37957 RB denotes also
T16477 37958-37966 VB denotes affected
T16478 37967-37970 CD denotes two
T16479 37971-37981 JJ denotes well-known
T16480 37982-37991 NN denotes functions
T16481 37992-37994 IN denotes of
T16482 37995-38001 NN denotes HTLV-I
T16483 38002-38005 NN denotes Tax
T16484 38005-38006 -COLON- denotes :
T16485 38007-38022 NN denotes transactivation
T16486 38023-38025 IN denotes of
T16487 38026-38029 DT denotes the
T16488 38030-38035 NN denotes NF-κB
T16489 38036-38043 NN denotes pathway
T16490 38044-38047 CC denotes and
T16491 38047-38048 -COMMA- denotes ,
T16492 38049-38053 RB denotes most
T16493 38054-38066 RB denotes surprisingly
T16494 38066-38067 -COMMA- denotes ,
T16495 38068-38083 NN denotes transactivation
T16496 38084-38086 IN denotes of
T16497 38087-38090 DT denotes the
T16498 38091-38097 NN denotes HTLV-I
T16499 38098-38101 NN denotes LTR
T16500 38103-38118 NN denotes Transactivation
T16501 38119-38121 IN denotes of
T16502 38122-38125 DT denotes the
T16503 38126-38132 NN denotes HTLV-I
T16504 38133-38136 NN denotes LTR
T16505 38137-38139 IN denotes by
T16506 38140-38143 NN denotes Tax
T16507 38144-38152 VB denotes involves
T16508 38153-38156 DT denotes the
T16509 38157-38168 NN denotes interaction
T16510 38169-38171 IN denotes of
T16511 38172-38180 NN denotes ATF/CREB
T16512 38181-38188 NN denotes factors
T16513 38189-38193 IN denotes with
T16514 38194-38197 NN denotes Tax
T16515 38198-38200 IN denotes in
T16516 38201-38204 DT denotes the
T16517 38205-38212 NN denotes nucleus
T16518 38214-38221 NN denotes Binding
T16519 38222-38224 IN denotes of
T16520 38225-38228 NN denotes Tax
T16521 38229-38237 VB denotes enhances
T16522 38238-38246 NN denotes ATF/CREB
T16523 38247-38259 NN denotes dimerization
T16524 38260-38263 CC denotes and
T16525 38264-38272 VB denotes promotes
T16526 38273-38281 NN denotes assembly
T16527 38282-38284 IN denotes of
T16528 38285-38297 NN denotes Tax-ATF/CREB
T16529 38298-38307 NN denotes complexes
T16530 38308-38312 IN denotes onto
T16531 38313-38321 JJ denotes specific
T16532 38322-38331 NN denotes sequences
T16533 38332-38334 IN denotes in
T16534 38335-38338 DT denotes the
T16535 38339-38344 JJ denotes viral
T16536 38345-38353 NN denotes promoter
T16537 38354-38359 VB denotes known
T16538 38360-38362 IN denotes as
T16539 38363-38377 JJ denotes Tax-responsive
T16540 38378-38386 NN denotes elements
T16541 38388-38392 DT denotes This
T16542 38393-38399 NN denotes series
T16543 38400-38402 IN denotes of
T16544 38403-38408 NN denotes steps
T16545 38409-38415 VB denotes allows
T16546 38416-38419 NN denotes Tax
T16547 38420-38422 TO denotes to
T16548 38423-38430 VB denotes recruit
T16549 38431-38442 NN denotes coactivator
T16550 38443-38451 NN denotes proteins
T16551 38452-38460 NN denotes CBP/p300
T16552 38461-38463 TO denotes to
T16553 38464-38467 DT denotes the
T16554 38468-38473 JJ denotes viral
T16555 38474-38482 NN denotes promoter
T16556 38483-38486 CC denotes and
T16557 38487-38497 VB denotes facilitate
T16558 38498-38499 DT denotes a
T16559 38500-38504 JJ denotes high
T16560 38505-38510 NN denotes level
T16561 38511-38513 IN denotes of
T16562 38514-38519 JJ denotes viral
T16563 38520-38524 NN denotes gene
T16564 38525-38535 NN denotes expression
T16565 38536-38537 -LRB- denotes [
T16566 38537-38542 CD denotes 24–26
T16567 38542-38543 -RRB- denotes ]
T16568 38545-38560 NN denotes Transactivation
T16569 38561-38563 IN denotes of
T16570 38564-38567 DT denotes the
T16571 38568-38573 NN denotes NF-κB
T16572 38574-38581 NN denotes pathway
T16573 38582-38584 IN denotes by
T16574 38585-38588 NN denotes Tax
T16575 38589-38592 VB denotes was
T16576 38593-38602 VB denotes inhibited
T16577 38603-38605 IN denotes by
T16578 38606-38620 NN denotes overexpression
T16579 38621-38623 IN denotes of
T16580 38624-38635 JJ denotes full-length
T16581 38636-38641 NN denotes Foxp3
T16582 38641-38642 -COMMA- denotes ,
T16583 38643-38646 CC denotes but
T16584 38647-38650 RB denotes not
T16585 38651-38655 NN denotes ΔFKH
T16586 38655-38656 -COMMA- denotes ,
T16587 38657-38659 IN denotes as
T16588 38660-38664 VB denotes seen
T16589 38665-38669 IN denotes with
T16590 38670-38675 JJ denotes basal
T16591 38676-38686 NN denotes activation
T16592 38687-38689 IN denotes of
T16593 38690-38693 DT denotes the
T16594 38694-38699 NN denotes HIV-1
T16595 38700-38703 NN denotes LTR
T16596 38704-38707 CC denotes and
T16597 38708-38709 DT denotes a
T16598 38710-38719 JJ denotes synthetic
T16599 38720-38725 NN denotes NF-κB
T16600 38726-38734 NN denotes reporter
T16601 38735-38737 IN denotes in
T16602 38738-38741 NN denotes HEK
T16603 38742-38746 NN denotes 293T
T16604 38747-38752 NN denotes cells
T16605 38754-38761 RB denotes However
T16606 38761-38762 -COMMA- denotes ,
T16607 38763-38775 JJ denotes Tax-mediated
T16608 38776-38791 NN denotes transactivation
T16609 38792-38794 IN denotes of
T16610 38795-38798 DT denotes the
T16611 38799-38805 NN denotes HTLV-I
T16612 38806-38809 NN denotes LTR
T16613 38810-38813 VB denotes was
T16614 38814-38823 VB denotes inhibited
T16615 38824-38826 IN denotes by
T16616 38827-38841 NN denotes overexpression
T16617 38842-38844 IN denotes of
T16618 38845-38849 CC denotes both
T16619 38850-38861 JJ denotes full-length
T16620 38862-38867 NN denotes Foxp3
T16621 38868-38870 RB denotes as
T16622 38871-38875 RB denotes well
T16623 38876-38878 IN denotes as
T16624 38879-38883 NN denotes ΔFKH
T16625 38884-38886 IN denotes in
T16626 38887-38891 CC denotes both
T16627 38892-38895 NN denotes HEK
T16628 38896-38900 NN denotes 293T
T16629 38901-38906 NN denotes cells
T16630 38907-38910 CC denotes and
T16631 38911-38915 JJ denotes CD4+
T16632 38916-38917 NN denotes T
T16633 38918-38923 NN denotes cells
T16634 38925-38927 PRP denotes We
T16635 38928-38940 VB denotes demonstrated
T16636 38941-38945 IN denotes that
T16637 38946-38951 NN denotes Foxp3
T16638 38952-38955 VB denotes did
T16639 38956-38959 RB denotes not
T16640 38960-38968 RB denotes directly
T16641 38969-38975 VB denotes affect
T16642 38976-38979 DT denotes the
T16643 38980-38991 NN denotes functioning
T16644 38992-38994 IN denotes of
T16645 38995-38998 NN denotes Tax
T16646 38998-38999 -COMMA- denotes ,
T16647 39000-39003 CC denotes but
T16648 39004-39010 RB denotes rather
T16649 39011-39016 CD denotes Foxp3
T16650 39017-39025 VB denotes targeted
T16651 39026-39029 DT denotes the
T16652 39030-39043 NN denotes transcription
T16653 39044-39051 NN denotes factors
T16654 39052-39060 VB denotes required
T16655 39061-39064 IN denotes for
T16656 39065-39068 NN denotes Tax
T16657 39069-39084 NN denotes transactivation
T16658 39085-39086 -LRB- denotes (
T16659 39086-39090 FW denotes i.e.
T16660 39090-39091 -COMMA- denotes ,
T16661 39092-39097 NN denotes NF-κB
T16662 39098-39101 CC denotes and
T16663 39102-39103 DT denotes a
T16664 39104-39116 JJ denotes then-unknown
T16665 39117-39125 JJ denotes cellular
T16666 39126-39132 NN denotes factor
T16667 39132-39133 -COMMA- denotes ,
T16668 39134-39139 WDT denotes which
T16669 39140-39142 PRP denotes we
T16670 39143-39153 VB denotes identified
T16671 39154-39156 IN denotes in
T16672 39157-39161 DT denotes this
T16673 39162-39167 NN denotes study
T16674 39168-39170 IN denotes as
T16675 39171-39175 NN denotes CREB
T16676 39175-39176 -RRB- denotes )
T16677 39178-39181 DT denotes The
T16678 39182-39190 JJ denotes negative
T16679 39191-39197 NN denotes effect
T16680 39198-39200 IN denotes of
T16681 39201-39206 NN denotes Foxp3
T16682 39207-39209 IN denotes on
T16683 39210-39216 NN denotes HTLV-I
T16684 39217-39221 NN denotes gene
T16685 39222-39232 NN denotes expression
T16686 39233-39236 VB denotes was
T16687 39237-39246 VB denotes confirmed
T16688 39247-39256 VB denotes utilizing
T16689 39257-39259 DT denotes an
T16690 39260-39266 NN denotes HTLV-I
T16691 39267-39277 JJ denotes infectious
T16692 39278-39287 JJ denotes molecular
T16693 39288-39293 NN denotes clone
T16694 39295-39306 RB denotes Importantly
T16695 39306-39307 -COMMA- denotes ,
T16696 39308-39310 PRP denotes we
T16697 39311-39323 VB denotes demonstrated
T16698 39324-39328 IN denotes that
T16699 39329-39344 JJ denotes HTLV-I-infected
T16700 39345-39356 NN denotes individuals
T16701 39357-39361 IN denotes with
T16702 39362-39365 DT denotes the
T16703 39366-39373 JJ denotes highest
T16704 39374-39380 NN denotes levels
T16705 39381-39383 IN denotes of
T16706 39384-39389 NN denotes Foxp3
T16707 39390-39397 NN denotes protein
T16708 39398-39408 NN denotes expression
T16709 39409-39415 IN denotes within
T16710 39416-39419 DT denotes the
T16711 39420-39429 JJ denotes CD4+CD25+
T16712 39430-39431 NN denotes T
T16713 39432-39437 NN denotes cells
T16714 39438-39448 NN denotes population
T16715 39449-39458 VB denotes exhibited
T16716 39459-39464 JJ denotes lower
T16717 39465-39473 JJ denotes proviral
T16718 39474-39479 NN denotes loads
T16719 39480-39484 IN denotes than
T16720 39485-39488 VB denotes did
T16721 39489-39500 NN denotes individuals
T16722 39501-39505 IN denotes with
T16723 39506-39509 DT denotes the
T16724 39510-39516 JJ denotes lowest
T16725 39517-39523 NN denotes levels
T16726 39524-39526 IN denotes of
T16727 39527-39532 NN denotes Foxp3
T16728 39533-39540 NN denotes protein
T16729 39541-39551 NN denotes expression
T16730 39553-39561 JJ denotes Previous
T16731 39562-39569 NN denotes studies
T16732 39570-39574 VB denotes have
T16733 39575-39587 VB denotes demonstrated
T16734 39588-39592 IN denotes that
T16735 39593-39596 DT denotes the
T16736 39597-39603 NN denotes HTLV-I
T16737 39604-39612 JJ denotes proviral
T16738 39613-39617 NN denotes load
T16739 39618-39626 RB denotes directly
T16740 39627-39637 VB denotes correlates
T16741 39638-39642 IN denotes with
T16742 39643-39649 NN denotes HTLV-I
T16743 39650-39653 NN denotes Tax
T16744 39654-39658 NN denotes mRNA
T16745 39659-39663 NN denotes load
T16746 39663-39664 -COMMA- denotes ,
T16747 39665-39668 DT denotes the
T16748 39669-39678 NN denotes frequency
T16749 39679-39681 IN denotes of
T16750 39682-39698 JJ denotes immunopathogenic
T16751 39699-39713 JJ denotes virus-specific
T16752 39714-39718 JJ denotes CD8+
T16753 39719-39720 NN denotes T
T16754 39721-39726 NN denotes cells
T16755 39726-39727 -COMMA- denotes ,
T16756 39728-39731 CC denotes and
T16757 39732-39739 NN denotes disease
T16758 39740-39748 NN denotes severity
T16759 39749-39751 IN denotes in
T16760 39752-39760 NN denotes patients
T16761 39761-39765 IN denotes with
T16762 39766-39773 NN denotes HAM/TSP
T16763 39774-39775 -LRB- denotes [
T16764 39775-39777 CD denotes 47
T16765 39777-39778 -RRB- denotes ]
T16766 39780-39785 DT denotes These
T16767 39786-39793 NN denotes results
T16768 39794-39798 VB denotes have
T16769 39799-39808 JJ denotes important
T16770 39809-39821 NN denotes implications
T16771 39822-39824 IN denotes on
T16772 39825-39828 DT denotes the
T16773 39829-39836 NN denotes utility
T16774 39837-39839 IN denotes of
T16775 39840-39845 NN denotes Foxp3
T16776 39846-39848 IN denotes in
T16777 39849-39860 VB denotes controlling
T16778 39861-39866 JJ denotes viral
T16779 39867-39871 NN denotes gene
T16780 39872-39882 NN denotes expression
T16781 39883-39886 CC denotes and
T16782 39887-39891 RB denotes thus
T16783 39892-39904 NN denotes pathogenesis
T16784 39905-39907 IN denotes of
T16785 39908-39915 NN denotes HAM/TSP
T16786 39917-39926 RB denotes Therefore
T16787 39926-39927 -COMMA- denotes ,
T16788 39928-39933 NN denotes Foxp3
T16789 39934-39941 VB denotes becomes
T16790 39942-39944 DT denotes an
T16791 39945-39955 JJ denotes attractive
T16792 39956-39962 NN denotes target
T16793 39963-39966 IN denotes for
T16794 39967-39970 DT denotes the
T16795 39971-39982 NN denotes development
T16796 39983-39985 IN denotes of
T16797 39986-39991 JJ denotes novel
T16798 39992-40003 JJ denotes therapeutic
T16799 40004-40016 NN denotes applications
T16800 40017-40025 VB denotes directed
T16801 40026-40028 IN denotes at
T16802 40029-40039 VB denotes modulating
T16803 40040-40043 DT denotes the
T16804 40044-40054 NN denotes expression
T16805 40055-40057 IN denotes of
T16806 40058-40062 DT denotes this
T16807 40063-40072 JJ denotes important
T16808 40073-40083 JJ denotes regulatory
T16809 40084-40091 NN denotes protein
T16810 40091-40092 -COMMA- denotes ,
T16811 40093-40103 RB denotes especially
T16812 40104-40106 IN denotes in
T16813 40107-40112 NN denotes light
T16814 40113-40115 IN denotes of
T16815 40116-40122 JJ denotes recent
T16816 40123-40135 NN denotes observations
T16817 40136-40140 IN denotes that
T16818 40141-40144 DT denotes the
T16819 40145-40155 NN denotes expression
T16820 40156-40158 IN denotes of
T16821 40159-40164 NN denotes Foxp3
T16822 40165-40168 MD denotes can
T16823 40169-40173 RB denotes also
T16824 40174-40176 VB denotes be
T16825 40177-40191 VB denotes down-regulated
T16826 40192-40194 IN denotes by
T16827 40195-40201 NN denotes HTLV-I
T16828 40202-40205 NN denotes Tax
T16829 40206-40207 -LRB- denotes [
T16830 40207-40208 CD denotes 8
T16831 40208-40209 -RRB- denotes ]
T16832 40211-40213 IN denotes As
T16833 40214-40217 DT denotes the
T16834 40218-40228 NN denotes activation
T16835 40229-40231 IN denotes of
T16836 40232-40235 DT denotes the
T16837 40236-40242 NN denotes HTLV-I
T16838 40243-40246 NN denotes LTR
T16839 40247-40254 VB denotes depends
T16840 40255-40264 RB denotes primarily
T16841 40265-40267 IN denotes on
T16842 40268-40276 NN denotes ATF/CREB
T16843 40277-40285 NN denotes proteins
T16844 40286-40287 -LRB- denotes (
T16845 40287-40294 IN denotes whether
T16846 40295-40297 IN denotes in
T16847 40298-40301 DT denotes the
T16848 40302-40310 NN denotes presence
T16849 40311-40313 CC denotes or
T16850 40314-40317 DT denotes the
T16851 40318-40325 NN denotes absence
T16852 40326-40328 IN denotes of
T16853 40329-40332 NN denotes Tax
T16854 40332-40333 -RRB- denotes )
T16855 40333-40334 -COMMA- denotes ,
T16856 40335-40337 PRP denotes we
T16857 40338-40350 VB denotes investigated
T16858 40351-40358 IN denotes whether
T16859 40359-40364 NN denotes Foxp3
T16860 40365-40370 MD denotes could
T16861 40371-40379 VB denotes interact
T16862 40380-40384 IN denotes with
T16863 40385-40389 DT denotes this
T16864 40390-40400 JJ denotes additional
T16865 40401-40409 JJ denotes cellular
T16866 40410-40419 NN denotes signaling
T16867 40420-40427 NN denotes pathway
T16868 40429-40434 IN denotes While
T16869 40435-40438 DT denotes the
T16870 40439-40450 JJ denotes DNA-binding
T16871 40451-40459 NN denotes activity
T16872 40460-40462 IN denotes of
T16873 40463-40467 NN denotes CREB
T16874 40468-40470 VB denotes is
T16875 40470-40471 -COMMA- denotes ,
T16876 40472-40474 IN denotes in
T16877 40475-40479 JJ denotes most
T16878 40480-40485 NN denotes cases
T16879 40485-40486 -COMMA- denotes ,
T16880 40487-40499 JJ denotes constitutive
T16881 40499-40500 -COMMA- denotes ,
T16882 40501-40504 DT denotes the
T16883 40505-40520 NN denotes transactivation
T16884 40521-40530 NN denotes potential
T16885 40531-40533 IN denotes of
T16886 40534-40538 NN denotes CREB
T16887 40539-40541 VB denotes is
T16888 40542-40551 VB denotes regulated
T16889 40552-40554 IN denotes by
T16890 40555-40558 DT denotes the
T16891 40559-40574 NN denotes phosphorylation
T16892 40575-40577 IN denotes of
T16893 40578-40582 NN denotes CREB
T16894 40583-40586 CC denotes and
T16895 40587-40598 NN denotes recruitment
T16896 40599-40601 IN denotes of
T16897 40602-40610 NN denotes CBP/p300
T16898 40611-40612 -LRB- denotes [
T16899 40612-40614 CD denotes 48
T16900 40614-40615 -RRB- denotes ]
T16901 40617-40620 PRP-DOLLAR- denotes Our
T16902 40621-40625 NN denotes data
T16903 40626-40637 VB denotes demonstrate
T16904 40638-40642 IN denotes that
T16905 40643-40648 NN denotes Foxp3
T16906 40649-40659 VB denotes interferes
T16907 40660-40664 IN denotes with
T16908 40665-40668 DT denotes the
T16909 40669-40675 JJ denotes latter
T16910 40676-40678 IN denotes of
T16911 40679-40684 DT denotes these
T16912 40685-40688 CD denotes two
T16913 40689-40698 NN denotes processes
T16914 40699-40702 CC denotes and
T16915 40703-40707 IN denotes that
T16916 40708-40711 DT denotes the
T16917 40712-40723 NN denotes recruitment
T16918 40724-40726 IN denotes of
T16919 40727-40730 DT denotes the
T16920 40731-40742 NN denotes coactivator
T16921 40743-40750 NN denotes protein
T16922 40751-40755 NN denotes p300
T16923 40755-40756 -COMMA- denotes ,
T16924 40757-40760 CC denotes and
T16925 40761-40770 VB denotes resulting
T16926 40771-40786 JJ denotes transcriptional
T16927 40787-40797 NN denotes activation
T16928 40798-40801 VB denotes are
T16929 40802-40809 VB denotes blocked
T16930 40810-40812 IN denotes by
T16931 40813-40818 NN denotes Foxp3
T16932 40820-40824 DT denotes This
T16933 40825-40828 MD denotes may
T16934 40829-40831 VB denotes be
T16935 40832-40835 DT denotes the
T16936 40836-40842 NN denotes result
T16937 40843-40845 IN denotes of
T16938 40846-40849 DT denotes the
T16939 40850-40858 JJ denotes physical
T16940 40859-40870 NN denotes interaction
T16941 40871-40873 PRP denotes we
T16942 40874-40882 VB denotes detected
T16943 40883-40890 IN denotes between
T16944 40891-40896 NN denotes Foxp3
T16945 40897-40900 CC denotes and
T16946 40901-40905 NN denotes p300
T16947 40907-40911 IN denotes With
T16948 40912-40919 NN denotes respect
T16949 40920-40922 TO denotes to
T16950 40923-40929 NN denotes HTLV-I
T16951 40930-40933 NN denotes LTR
T16952 40934-40942 NN denotes activity
T16953 40942-40943 -COMMA- denotes ,
T16954 40944-40949 IN denotes while
T16955 40950-40961 JJ denotes full-length
T16956 40962-40967 NN denotes Foxp3
T16957 40968-40977 VB denotes inhibited
T16958 40978-40982 CC denotes both
T16959 40983-40988 JJ denotes basal
T16960 40989-40992 CC denotes and
T16961 40993-41006 JJ denotes Tax-dependent
T16962 41007-41020 NN denotes transcription
T16963 41021-41023 IN denotes by
T16964 41024-41027 CD denotes ~50
T16965 41027-41028 NN denotes %
T16966 41028-41029 -COMMA- denotes ,
T16967 41030-41034 NN denotes ΔFKH
T16968 41035-41043 VB denotes appeared
T16969 41044-41048 RB denotes less
T16970 41049-41058 JJ denotes effective
T16971 41059-41061 IN denotes in
T16972 41062-41073 VB denotes suppressing
T16973 41074-41079 JJ denotes basal
T16974 41080-41090 NN denotes activation
T16975 41091-41092 -LRB- denotes (
T16976 41092-41095 CD denotes ~25
T16977 41095-41096 NN denotes %
T16978 41097-41107 NN denotes inhibition
T16979 41107-41108 -RRB- denotes )
T16980 41109-41117 VB denotes compared
T16981 41118-41120 TO denotes to
T16982 41121-41134 JJ denotes Tax-dependent
T16983 41135-41145 NN denotes activation
T16984 41146-41147 -LRB- denotes (
T16985 41147-41150 CD denotes ~50
T16986 41150-41151 NN denotes %
T16987 41152-41162 NN denotes inhibition
T16988 41162-41163 -RRB- denotes )
T16989 41165-41168 DT denotes The
T16990 41169-41175 NN denotes effect
T16991 41176-41178 IN denotes of
T16992 41179-41183 NN denotes ΔFKH
T16993 41184-41186 IN denotes on
T16994 41187-41192 JJ denotes basal
T16995 41193-41203 NN denotes activation
T16996 41204-41206 IN denotes of
T16997 41207-41210 DT denotes the
T16998 41211-41217 NN denotes HTLV-I
T16999 41218-41221 NN denotes LTR
T17000 41222-41224 IN denotes in
T17001 41225-41228 NN denotes HEK
T17002 41229-41233 NN denotes 293T
T17003 41234-41239 NN denotes cells
T17004 41240-41243 VB denotes was
T17005 41244-41248 RB denotes very
T17006 41249-41256 JJ denotes similar
T17007 41257-41259 TO denotes to
T17008 41260-41264 DT denotes that
T17009 41265-41270 VB denotes shown
T17010 41271-41274 IN denotes for
T17011 41275-41276 DT denotes a
T17012 41277-41286 JJ denotes synthetic
T17013 41287-41291 NN denotes CREB
T17014 41292-41300 NN denotes reporter
T17015 41300-41301 -COMMA- denotes ,
T17016 41302-41312 VB denotes suggesting
T17017 41313-41317 IN denotes that
T17018 41318-41321 DT denotes the
T17019 41322-41325 NN denotes FKH
T17020 41326-41332 NN denotes domain
T17021 41333-41335 IN denotes of
T17022 41336-41341 NN denotes Foxp3
T17023 41342-41344 VB denotes is
T17024 41345-41354 JJ denotes important
T17025 41355-41357 IN denotes at
T17026 41358-41362 DT denotes some
T17027 41363-41368 NN denotes level
T17028 41370-41372 IN denotes As
T17029 41373-41381 VB denotes observed
T17030 41382-41386 IN denotes with
T17031 41387-41392 NN denotes NF-κB
T17032 41393-41403 NN denotes activation
T17033 41403-41404 -COMMA- denotes ,
T17034 41405-41408 DT denotes the
T17035 41409-41414 NN denotes Foxp3
T17036 41415-41421 NN denotes mutant
T17037 41422-41429 VB denotes lacking
T17038 41430-41433 DT denotes the
T17039 41434-41437 NN denotes FKH
T17040 41438-41444 NN denotes domain
T17041 41445-41448 VB denotes was
T17042 41449-41450 DT denotes a
T17043 41451-41459 JJ denotes stronger
T17044 41460-41469 NN denotes inhibitor
T17045 41470-41472 IN denotes of
T17046 41473-41477 NN denotes CREB
T17047 41478-41488 NN denotes activation
T17048 41489-41491 IN denotes in
T17049 41492-41496 JJ denotes CD4+
T17050 41497-41498 NN denotes T
T17051 41499-41504 NN denotes cells
T17052 41505-41509 IN denotes than
T17053 41510-41512 IN denotes in
T17054 41513-41516 NN denotes HEK
T17055 41517-41521 NN denotes 293T
T17056 41522-41532 JJ denotes epithelial
T17057 41533-41538 NN denotes cells
T17058 41540-41549 RB denotes Therefore
T17059 41549-41550 -COMMA- denotes ,
T17060 41551-41553 PRP denotes it
T17061 41554-41561 VB denotes appears
T17062 41562-41566 IN denotes that
T17063 41567-41569 IN denotes in
T17064 41570-41574 JJ denotes CD4+
T17065 41575-41576 NN denotes T
T17066 41577-41582 NN denotes cells
T17067 41582-41583 -COMMA- denotes ,
T17068 41584-41587 DT denotes the
T17069 41588-41591 NN denotes FKH
T17070 41592-41598 NN denotes domain
T17071 41599-41601 VB denotes is
T17072 41602-41613 JJ denotes dispensable
T17073 41614-41617 IN denotes for
T17074 41618-41621 DT denotes the
T17075 41622-41628 JJ denotes proper
T17076 41629-41640 NN denotes functioning
T17077 41641-41643 IN denotes of
T17078 41644-41649 NN denotes Foxp3
T17079 41650-41654 IN denotes with
T17080 41655-41662 NN denotes respect
T17081 41663-41665 TO denotes to
T17082 41666-41670 CC denotes both
T17083 41671-41676 NN denotes NF-κB
T17084 41677-41680 CC denotes and
T17085 41681-41685 NN denotes CREB
T17086 41686-41696 NN denotes activation
T17087 41698-41700 IN denotes In
T17088 41701-41708 NN denotes summary
T17089 41708-41709 -COMMA- denotes ,
T17090 41710-41714 DT denotes this
T17091 41715-41717 VB denotes is
T17092 41717-41718 -COMMA- denotes ,
T17093 41719-41721 TO denotes to
T17094 41722-41725 PRP-DOLLAR- denotes our
T17095 41726-41735 NN denotes knowledge
T17096 41735-41736 -COMMA- denotes ,
T17097 41737-41740 DT denotes the
T17098 41741-41746 JJ denotes first
T17099 41747-41753 JJ denotes direct
T17100 41754-41762 NN denotes evidence
T17101 41763-41774 VB denotes implicating
T17102 41775-41776 DT denotes a
T17103 41777-41781 NN denotes role
T17104 41782-41785 IN denotes for
T17105 41786-41789 DT denotes the
T17106 41790-41803 JJ denotes Treg-specific
T17107 41804-41817 NN denotes transcription
T17108 41818-41824 NN denotes factor
T17109 41825-41830 NN denotes Foxp3
T17110 41831-41833 IN denotes in
T17111 41834-41844 VB denotes regulating
T17112 41845-41855 JJ denotes retroviral
T17113 41856-41860 NN denotes gene
T17114 41861-41871 NN denotes expression
T17115 41873-41875 IN denotes In
T17116 41876-41884 NN denotes addition
T17117 41884-41885 -COMMA- denotes ,
T17118 41886-41888 PRP denotes we
T17119 41889-41897 VB denotes identify
T17120 41898-41901 DT denotes the
T17121 41902-41906 NN denotes CREB
T17122 41907-41914 NN denotes pathway
T17123 41915-41917 IN denotes as
T17124 41918-41919 DT denotes a
T17125 41920-41929 JJ denotes molecular
T17126 41930-41936 NN denotes target
T17127 41937-41939 IN denotes of
T17128 41940-41945 NN denotes Foxp3
T17129 41947-41952 IN denotes Since
T17130 41953-41957 NN denotes CREB
T17131 41958-41961 VB denotes has
T17132 41962-41966 VB denotes been
T17133 41967-41972 VB denotes shown
T17134 41973-41975 TO denotes to
T17135 41976-41984 VB denotes regulate
T17136 41985-41993 JJ denotes multiple
T17137 41994-41999 NN denotes genes
T17138 42000-42008 VB denotes involved
T17139 42009-42011 IN denotes in
T17140 42012-42025 NN denotes transcription
T17141 42026-42027 -LRB- denotes (
T17142 42027-42031 FW denotes e.g.
T17143 42031-42032 -COMMA- denotes ,
T17144 42033-42037 NN denotes JunD
T17145 42037-42038 -COMMA- denotes ,
T17146 42039-42044 NN denotes c-Fos
T17147 42044-42045 -COMMA- denotes ,
T17148 42046-42052 NN denotes signal
T17149 42053-42063 NN denotes transducer
T17150 42064-42066 IN denotes of
T17151 42067-42076 VB denotes activated
T17152 42077-42078 NN denotes T
T17153 42079-42084 NN denotes cells
T17154 42085-42086 CD denotes 3
T17155 42087-42088 -LRB- denotes [
T17156 42088-42093 NN denotes STAT3
T17157 42093-42094 -RRB- denotes ]
T17158 42094-42095 -RRB- denotes )
T17159 42095-42096 -COMMA- denotes ,
T17160 42097-42101 NN denotes cell
T17161 42102-42107 NN denotes cycle
T17162 42108-42109 -LRB- denotes (
T17163 42109-42113 FW denotes e.g.
T17164 42113-42114 -COMMA- denotes ,
T17165 42115-42123 NN denotes p15INK4b
T17166 42123-42124 -COMMA- denotes ,
T17167 42125-42131 NN denotes cyclin
T17168 42132-42133 NN denotes A
T17169 42133-42134 -COMMA- denotes ,
T17170 42135-42141 NN denotes cyclin
T17171 42142-42144 NN denotes D1
T17172 42144-42145 -RRB- denotes )
T17173 42145-42146 -COMMA- denotes ,
T17174 42147-42150 CC denotes and
T17175 42151-42157 JJ denotes immune
T17176 42158-42168 NN denotes regulation
T17177 42169-42170 -LRB- denotes (
T17178 42170-42174 FW denotes e.g.
T17179 42174-42175 -COMMA- denotes ,
T17180 42176-42180 NN denotes IL-2
T17181 42180-42181 -COMMA- denotes ,
T17182 42182-42186 NN denotes IL-6
T17183 42186-42187 -COMMA- denotes ,
T17184 42188-42194 NN denotes T-cell
T17185 42195-42203 NN denotes receptor
T17186 42204-42205 NN denotes α
T17187 42205-42206 -RRB- denotes )
T17188 42207-42208 -LRB- denotes (
T17189 42208-42216 VB denotes reviewed
T17190 42217-42219 IN denotes in
T17191 42220-42221 -LRB- denotes [
T17192 42221-42223 CD denotes 48
T17193 42223-42224 -RRB- denotes ]
T17194 42224-42225 -RRB- denotes )
T17195 42225-42226 -COMMA- denotes ,
T17196 42227-42230 DT denotes the
T17197 42231-42239 NN denotes findings
T17198 42240-42249 VB denotes presented
T17199 42250-42252 IN denotes in
T17200 42253-42257 DT denotes this
T17201 42258-42264 NN denotes report
T17202 42265-42272 NN denotes broaden
T17203 42273-42276 DT denotes the
T17204 42277-42286 JJ denotes potential
T17205 42287-42292 NN denotes range
T17206 42293-42295 IN denotes of
T17207 42296-42305 NN denotes signaling
T17208 42306-42314 NN denotes pathways
T17209 42315-42320 IN denotes under
T17210 42321-42324 DT denotes the
T17211 42325-42332 NN denotes control
T17212 42333-42335 IN denotes of
T17213 42336-42339 DT denotes the
T17214 42340-42350 JJ denotes regulatory
T17215 42351-42358 NN denotes protein
T17216 42359-42364 NN denotes Foxp3
T17217 42366-42369 PRP-DOLLAR- denotes Our
T17218 42370-42378 NN denotes evidence
T17219 42379-42387 VB denotes stresses
T17220 42388-42391 DT denotes the
T17221 42392-42402 NN denotes importance
T17222 42403-42405 IN denotes of
T17223 42406-42411 NN denotes Foxp3
T17224 42412-42422 NN denotes expression
T17225 42423-42426 CC denotes and
T17226 42427-42431 NN denotes Treg
T17227 42432-42440 NN denotes function
T17228 42441-42443 IN denotes in
T17229 42444-42447 DT denotes the
T17230 42448-42459 NN denotes development
T17231 42460-42463 CC denotes and
T17232 42464-42475 NN denotes maintenance
T17233 42476-42478 IN denotes of
T17234 42479-42489 JJ denotes protective
T17235 42490-42498 NN denotes immunity
T17236 42499-42506 IN denotes against
T17237 42507-42512 NN denotes HIV-1
T17238 42513-42516 CC denotes and
T17239 42517-42524 NN denotes HTLV-I.
T17240 42525-42530 VB denotes Based
T17241 42531-42533 IN denotes on
T17242 42534-42540 JJ denotes recent
T17243 42541-42549 NN denotes findings
T17244 42549-42550 -COMMA- denotes ,
T17245 42551-42556 NN denotes Foxp3
T17246 42557-42560 MD denotes may
T17247 42561-42566 VB denotes limit
T17248 42567-42572 NN denotes HIV-1
T17249 42573-42576 CC denotes and
T17250 42577-42583 NN denotes HTLV-I
T17251 42584-42597 NN denotes transcription
T17252 42598-42600 IN denotes by
T17253 42601-42612 VB denotes interfering
T17254 42613-42617 IN denotes with
T17255 42618-42628 NN denotes activation
T17256 42629-42631 IN denotes of
T17257 42632-42637 NN denotes NF-κB
T17258 42638-42641 CC denotes and
T17259 42642-42646 NN denotes CREB
T17260 42647-42655 NN denotes pathways
T17261 42657-42664 RB denotes However
T17262 42664-42665 -COMMA- denotes ,
T17263 42666-42675 VB denotes observing
T17264 42676-42680 IN denotes that
T17265 42681-42685 DT denotes this
T17266 42686-42696 JJ denotes inhibitory
T17267 42697-42703 NN denotes effect
T17268 42704-42706 VB denotes is
T17269 42707-42710 RB denotes not
T17270 42711-42719 JJ denotes absolute
T17271 42719-42720 -COMMA- denotes ,
T17272 42721-42722 DT denotes a
T17273 42723-42726 JJ denotes low
T17274 42727-42732 NN denotes level
T17275 42733-42735 IN denotes of
T17276 42736-42741 JJ denotes viral
T17277 42742-42746 NN denotes gene
T17278 42747-42757 NN denotes expression
T17279 42758-42761 MD denotes may
T17280 42762-42769 VB denotes persist
T17281 42770-42772 IN denotes in
T17282 42773-42777 JJ denotes CD4+
T17283 42778-42779 NN denotes T
T17284 42780-42785 NN denotes cells
T17285 42786-42787 -LRB- denotes (
T17286 42787-42789 IN denotes in
T17287 42790-42800 JJ denotes particular
T17288 42801-42811 JJ denotes regulatory
T17289 42812-42813 NN denotes T
T17290 42814-42819 NN denotes cells
T17291 42819-42820 -COMMA- denotes ,
T17292 42821-42826 WDT denotes which
T17293 42827-42830 VB denotes are
T17294 42831-42836 VB denotes known
T17295 42837-42847 NN denotes reservoirs
T17296 42848-42850 IN denotes of
T17297 42851-42856 NN denotes HIV-1
T17298 42857-42860 CC denotes and
T17299 42861-42867 NN denotes HTLV-I
T17300 42867-42868 -RRB- denotes )
T17301 42869-42872 CC denotes and
T17302 42873-42879 VB denotes result
T17303 42880-42882 IN denotes in
T17304 42883-42886 DT denotes the
T17305 42887-42899 NN denotes accumulation
T17306 42900-42902 IN denotes of
T17307 42903-42908 JJ denotes viral
T17308 42909-42917 NN denotes proteins
T17309 42918-42922 WDT denotes that
T17310 42923-42929 CC denotes either
T17311 42930-42939 VB denotes stimulate
T17312 42940-42945 NN denotes NF-κB
T17313 42946-42952 CC denotes and/or
T17314 42953-42957 NN denotes CREB
T17315 42958-42968 NN denotes activation
T17316 42969-42971 CC denotes or
T17317 42972-42980 RB denotes directly
T17318 42981-42988 VB denotes inhibit
T17319 42989-42994 NN denotes Foxp3
T17320 42995-43005 NN denotes expression
T17321 43006-43008 CC denotes or
T17322 43009-43017 NN denotes function
T17323 43019-43022 DT denotes The
T17324 43023-43032 NN denotes imbalance
T17325 43033-43035 IN denotes of
T17326 43036-43041 NN denotes NF-κB
T17327 43042-43045 CC denotes and
T17328 43046-43050 NN denotes CREB
T17329 43051-43061 NN denotes activation
T17330 43062-43068 VB denotes caused
T17331 43069-43071 IN denotes by
T17332 43072-43077 DT denotes these
T17333 43078-43083 JJ denotes viral
T17334 43084-43088 NN denotes gene
T17335 43089-43097 NN denotes products
T17336 43098-43101 MD denotes may
T17337 43102-43104 VB denotes be
T17338 43105-43106 DT denotes a
T17339 43107-43114 JJ denotes crucial
T17340 43115-43119 NN denotes step
T17341 43120-43122 IN denotes in
T17342 43123-43126 DT denotes the
T17343 43127-43139 NN denotes pathogenesis
T17344 43140-43142 IN denotes of
T17345 43143-43156 JJ denotes virus-induced
T17346 43157-43170 JJ denotes immunological
T17347 43171-43180 NN denotes disorders
T17348 43181-43185 JJ denotes such
T17349 43186-43188 IN denotes as
T17350 43189-43193 NN denotes AIDS
T17351 43194-43197 CC denotes and
T17352 43198-43205 NN denotes HAM/TSP
T17353 43207-43213 JJ denotes Future
T17354 43214-43221 NN denotes studies
T17355 43222-43226 MD denotes will
T17356 43227-43229 VB denotes be
T17357 43230-43238 VB denotes directed
T17358 43239-43241 IN denotes at
T17359 43242-43253 VB denotes identifying
T17360 43254-43257 CC denotes and
T17361 43258-43272 VB denotes characterizing
T17362 43273-43281 JJ denotes cellular
T17363 43282-43290 NN denotes proteins
T17364 43291-43295 WDT denotes that
T17365 43296-43304 VB denotes interact
T17366 43305-43309 IN denotes with
T17367 43310-43315 NN denotes Foxp3
T17368 43316-43320 CC denotes both
T17369 43321-43323 IN denotes in
T17370 43324-43327 DT denotes the
T17371 43328-43335 NN denotes nucleus
T17372 43336-43339 CC denotes and
T17373 43340-43349 NN denotes cytoplasm
T17374 43349-43350 -COMMA- denotes ,
T17375 43351-43353 IN denotes in
T17376 43354-43359 NN denotes order
T17377 43360-43362 TO denotes to
T17378 43363-43369 RB denotes better
T17379 43370-43377 VB denotes address
T17380 43378-43381 WRB denotes how
T17381 43382-43387 NN denotes Foxp3
T17382 43388-43397 NN denotes functions
T17383 43398-43400 TO denotes to
T17384 43401-43406 VB denotes guide
T17385 43407-43410 DT denotes the
T17386 43411-43422 NN denotes development
T17387 43423-43426 CC denotes and
T17388 43427-43435 NN denotes function
T17389 43436-43438 IN denotes of
T17390 43439-43449 JJ denotes regulatory
T17391 43450-43451 NN denotes T
T17392 43452-43457 NN denotes cells
T17393 43458-43460 IN denotes in
T17394 43461-43467 NN denotes health
T17395 43468-43471 CC denotes and
T17396 43472-43479 NN denotes disease
T18818 43505-43509 NN denotes Cell
T18819 43510-43517 NN denotes culture
T18820 43519-43522 NN denotes HEK
T18821 43523-43527 NN denotes 293T
T18822 43528-43533 NN denotes cells
T18823 43534-43538 VB denotes were
T18824 43539-43547 VB denotes cultured
T18825 43548-43550 IN denotes in
T18826 43551-43559 NNP denotes Dulbecco
T18827 43559-43561 POS denotes 's
T18828 43562-43570 JJ denotes modified
T18829 43571-43576 NNP denotes Eagle
T18830 43577-43583 NN denotes medium
T18831 43584-43585 -LRB- denotes (
T18832 43585-43595 NN denotes Invitrogen
T18833 43595-43596 -COMMA- denotes ,
T18834 43597-43605 NNP denotes Carlsbad
T18835 43605-43606 -COMMA- denotes ,
T18836 43607-43617 NNP denotes California
T18837 43617-43618 -COMMA- denotes ,
T18838 43619-43625 NNP denotes United
T18839 43626-43632 NNP denotes States
T18840 43632-43633 -RRB- denotes )
T18841 43635-43641 NN denotes Jurkat
T18842 43642-43643 NN denotes T
T18843 43644-43649 NN denotes cells
T18844 43650-43653 CC denotes and
T18845 43654-43661 JJ denotes primary
T18846 43662-43667 JJ denotes human
T18847 43668-43672 JJ denotes CD4+
T18848 43673-43674 NN denotes T
T18849 43675-43680 NN denotes cells
T18850 43681-43685 VB denotes were
T18851 43686-43694 VB denotes cultured
T18852 43695-43697 IN denotes in
T18853 43698-43707 NN denotes RPMI-1640
T18854 43708-43714 NN denotes medium
T18855 43715-43716 -LRB- denotes (
T18856 43716-43726 NN denotes Invitrogen
T18857 43726-43727 -RRB- denotes )
T18858 43729-43734 NN denotes Media
T18859 43735-43739 VB denotes were
T18860 43740-43752 VB denotes supplemented
T18861 43753-43757 IN denotes with
T18862 43758-43759 CD denotes 2
T18863 43760-43762 NN denotes mM
T18864 43763-43774 NN denotes L-glutamine
T18865 43774-43775 -COMMA- denotes ,
T18866 43776-43779 CD denotes 100
T18867 43780-43784 NN denotes U/ml
T18868 43785-43795 NN denotes penicillin
T18869 43795-43796 -COMMA- denotes ,
T18870 43797-43800 CD denotes 100
T18871 43801-43806 NN denotes μg/ml
T18872 43807-43819 NN denotes streptomycin
T18873 43820-43821 -LRB- denotes (
T18874 43821-43828 NNP denotes Cambrex
T18875 43828-43829 -COMMA- denotes ,
T18876 43830-43834 NNP denotes East
T18877 43835-43845 NNP denotes Rutherford
T18878 43845-43846 -COMMA- denotes ,
T18879 43847-43850 NNP denotes New
T18880 43851-43857 NNP denotes Jersey
T18881 43857-43858 -COMMA- denotes ,
T18882 43859-43865 NNP denotes United
T18883 43866-43872 NNP denotes States
T18884 43872-43873 -RRB- denotes )
T18885 43873-43874 -COMMA- denotes ,
T18886 43875-43878 CC denotes and
T18887 43879-43881 CD denotes 10
T18888 43881-43882 NN denotes %
T18889 43883-43888 JJ denotes fetal
T18890 43889-43895 JJ denotes bovine
T18891 43896-43901 NN denotes serum
T18892 43902-43903 -LRB- denotes (
T18893 43903-43910 NNP denotes Atlanta
T18894 43911-43922 NNP denotes Biologicals
T18895 43922-43923 -COMMA- denotes ,
T18896 43924-43932 NNP denotes Norcross
T18897 43932-43933 -COMMA- denotes ,
T18898 43934-43941 NNP denotes Georgia
T18899 43941-43942 -COMMA- denotes ,
T18900 43943-43949 NNP denotes United
T18901 43950-43956 NNP denotes States
T18902 43956-43957 -RRB- denotes )
T19040 43960-43968 NN denotes Patients
T19041 43969-43972 CC denotes and
T19042 43973-43977 NN denotes cell
T19043 43978-43989 NN denotes preparation
T19044 43991-43996 NN denotes PBMCs
T19045 43997-44001 VB denotes were
T19046 44002-44010 VB denotes prepared
T19047 44011-44013 IN denotes by
T19048 44014-44028 NN denotes centrifugation
T19049 44029-44033 IN denotes over
T19050 44034-44048 JJ denotes Ficoll-Hypaque
T19051 44049-44058 NN denotes gradients
T19052 44059-44060 -LRB- denotes (
T19053 44060-44072 NNP denotes BioWhittaker
T19054 44072-44073 -COMMA- denotes ,
T19055 44074-44086 NNP denotes Walkersville
T19056 44086-44087 -COMMA- denotes ,
T19057 44088-44096 NNP denotes Maryland
T19058 44096-44097 -COMMA- denotes ,
T19059 44098-44104 NNP denotes United
T19060 44105-44111 NNP denotes States
T19061 44111-44112 -RRB- denotes )
T19062 44113-44117 IN denotes from
T19063 44118-44123 CD denotes eight
T19064 44124-44131 NN denotes HAM/TSP
T19065 44132-44140 NN denotes patients
T19066 44141-44144 CC denotes and
T19067 44145-44150 CD denotes eight
T19068 44151-44154 NN denotes ACs
T19069 44154-44155 -COMMA- denotes ,
T19070 44156-44159 CC denotes and
T19071 44160-44163 DT denotes the
T19072 44164-44169 NN denotes cells
T19073 44170-44174 VB denotes were
T19074 44175-44181 RB denotes viably
T19075 44182-44195 VB denotes cryopreserved
T19076 44196-44198 IN denotes in
T19077 44199-44205 JJ denotes liquid
T19078 44206-44214 NN denotes nitrogen
T19079 44215-44220 IN denotes until
T19080 44221-44227 VB denotes tested
T19081 44229-44236 NN denotes HAM/TSP
T19082 44237-44240 VB denotes was
T19083 44241-44250 VB denotes diagnosed
T19084 44251-44260 VB denotes according
T19085 44261-44263 TO denotes to
T19086 44264-44267 NN denotes WHO
T19087 44268-44278 NN denotes guidelines
T19088 44279-44280 -LRB- denotes [
T19089 44280-44282 CD denotes 49
T19090 44282-44283 -RRB- denotes ]
T19091 44285-44291 NN denotes HTLV-I
T19092 44292-44306 NN denotes seropositivity
T19093 44307-44310 VB denotes was
T19094 44311-44321 VB denotes determined
T19095 44322-44324 IN denotes by
T19096 44325-44330 NN denotes ELISA
T19097 44331-44332 -LRB- denotes (
T19098 44332-44338 NNP denotes Abbott
T19099 44339-44351 NNP denotes Laboratories
T19100 44351-44352 -COMMA- denotes ,
T19101 44353-44359 NNP denotes Abbott
T19102 44360-44364 NNP denotes Park
T19103 44364-44365 -COMMA- denotes ,
T19104 44366-44374 NNP denotes Illinois
T19105 44374-44375 -COMMA- denotes ,
T19106 44376-44382 NNP denotes United
T19107 44383-44389 NNP denotes States
T19108 44389-44390 -RRB- denotes )
T19109 44390-44391 -COMMA- denotes ,
T19110 44392-44396 IN denotes with
T19111 44397-44409 NN denotes confirmation
T19112 44410-44412 IN denotes by
T19113 44413-44420 JJ denotes Western
T19114 44421-44425 NN denotes blot
T19115 44426-44434 NN denotes analysis
T19116 44435-44436 -LRB- denotes (
T19117 44436-44444 NNP denotes Genelabs
T19118 44445-44457 NNP denotes Technologies
T19119 44457-44458 -COMMA- denotes ,
T19120 44459-44466 NNP denotes Redwood
T19121 44467-44471 NNP denotes City
T19122 44471-44472 -COMMA- denotes ,
T19123 44473-44483 NNP denotes California
T19124 44483-44484 -COMMA- denotes ,
T19125 44485-44491 NNP denotes United
T19126 44492-44498 NNP denotes States
T19127 44498-44499 -RRB- denotes )
T19128 44501-44506 NN denotes Blood
T19129 44507-44514 NN denotes samples
T19130 44515-44519 VB denotes were
T19131 44520-44528 VB denotes obtained
T19132 44529-44534 IN denotes after
T19133 44535-44543 VB denotes informed
T19134 44544-44551 NN denotes consent
T19135 44552-44554 IN denotes as
T19136 44555-44559 NN denotes part
T19137 44560-44562 IN denotes of
T19138 44563-44564 DT denotes a
T19139 44565-44573 JJ denotes clinical
T19140 44574-44582 NN denotes protocol
T19141 44583-44591 VB denotes reviewed
T19142 44592-44595 CC denotes and
T19143 44596-44604 VB denotes approved
T19144 44605-44607 IN denotes by
T19145 44608-44611 DT denotes the
T19146 44612-44615 NNP denotes NIH
T19147 44616-44629 JJ denotes institutional
T19148 44630-44636 NN denotes review
T19149 44637-44642 NN denotes panel
T19777 46137-46146 NN denotes Isolation
T19778 46147-46149 IN denotes of
T19779 46150-46157 JJ denotes primary
T19780 46158-46163 JJ denotes human
T19781 46164-46168 JJ denotes CD4+
T19782 46169-46170 NN denotes T
T19783 46171-46176 NN denotes cells
T19784 46178-46182 JJ denotes CD4+
T19785 46183-46184 NN denotes T
T19786 46185-46190 NN denotes cells
T19787 46191-46195 VB denotes were
T19788 46196-46204 VB denotes isolated
T19789 46205-46209 IN denotes from
T19790 46210-46223 VB denotes cryopreserved
T19791 46224-46231 JJ denotes healthy
T19792 46232-46237 NN denotes donor
T19793 46238-46243 NN denotes PBMCs
T19794 46244-46246 IN denotes by
T19795 46247-46255 JJ denotes negative
T19796 46256-46265 NN denotes selection
T19797 46266-46270 IN denotes with
T19798 46271-46274 DT denotes the
T19799 46275-46279 JJ denotes CD4+
T19800 46280-46281 NN denotes T
T19801 46282-46286 NN denotes Cell
T19802 46287-46296 NN denotes Isolation
T19803 46297-46300 NN denotes Kit
T19804 46301-46303 CD denotes II
T19805 46304-46305 -LRB- denotes (
T19806 46305-46313 NNP denotes Miltenyi
T19807 46314-46321 NNP denotes Biotech
T19808 46321-46322 -COMMA- denotes ,
T19809 46323-46331 NNP denotes Bergisch
T19810 46332-46340 NNP denotes Gladbach
T19811 46340-46341 -COMMA- denotes ,
T19812 46342-46349 NNP denotes Germany
T19813 46349-46350 -RRB- denotes )
T19814 46351-46360 VB denotes according
T19815 46361-46363 TO denotes to
T19816 46364-46376 NN denotes manufacturer
T19817 46376-46378 POS denotes 's
T19818 46379-46389 NN denotes guidelines
T19819 46391-46397 NN denotes Purity
T19820 46398-46400 IN denotes of
T19821 46401-46411 RB denotes negatively
T19822 46412-46420 VB denotes selected
T19823 46421-46425 JJ denotes CD4+
T19824 46426-46427 NN denotes T
T19825 46428-46433 NN denotes cells
T19826 46434-46437 VB denotes was
T19827 46438-46450 RB denotes consistently
T19828 46451-46457 JJ denotes higher
T19829 46458-46462 IN denotes than
T19830 46463-46465 CD denotes 96
T19831 46465-46466 NN denotes %
T19832 46467-46469 IN denotes as
T19833 46470-46480 VB denotes determined
T19834 46481-46483 IN denotes by
T19835 46484-46488 NN denotes flow
T19836 46489-46498 NN denotes cytometry
T20207 46501-46510 JJ denotes Transient
T20208 46511-46521 NN denotes expression
T20209 46522-46525 CC denotes and
T20210 46526-46536 NN denotes luciferase
T20211 46537-46543 NN denotes assays
T20212 46545-46548 NN denotes HEK
T20213 46549-46553 NN denotes 293T
T20214 46554-46559 NN denotes cells
T20215 46560-46564 VB denotes were
T20216 46565-46571 VB denotes plated
T20217 46572-46574 IN denotes at
T20218 46575-46576 DT denotes a
T20219 46577-46584 NN denotes density
T20220 46585-46587 IN denotes of
T20221 46588-46589 CD denotes 5
T20222 46590-46591 IN denotes ×
T20223 46592-46595 CD denotes 105
T20224 46596-46606 NN denotes cells/well
T20225 46607-46609 IN denotes in
T20226 46610-46618 JJ denotes six-well
T20227 46619-46626 NN denotes culture
T20228 46627-46633 NN denotes plates
T20229 46634-46635 -LRB- denotes (
T20230 46635-46637 NN denotes BD
T20231 46638-46649 NNP denotes Biosciences
T20232 46649-46650 -COMMA- denotes ,
T20233 46651-46654 NNP denotes San
T20234 46655-46660 NNP denotes Diego
T20235 46660-46661 -COMMA- denotes ,
T20236 46662-46672 NNP denotes California
T20237 46672-46673 -COMMA- denotes ,
T20238 46674-46680 NNP denotes United
T20239 46681-46687 NNP denotes States
T20240 46687-46688 -RRB- denotes )
T20241 46689-46690 CD denotes 1
T20242 46691-46692 NN denotes d
T20243 46693-46698 JJ denotes prior
T20244 46699-46701 TO denotes to
T20245 46702-46714 NN denotes transfection
T20246 46715-46719 IN denotes with
T20247 46720-46723 DT denotes the
T20248 46724-46735 JJ denotes appropriate
T20249 46736-46743 NN denotes plasmid
T20250 46744-46747 NN denotes DNA
T20251 46748-46749 -LRB- denotes (
T20252 46749-46751 CD denotes ~2
T20253 46752-46754 NN denotes μg
T20254 46755-46760 NN denotes total
T20255 46760-46761 -RRB- denotes )
T20256 46762-46767 VB denotes using
T20257 46768-46774 NN denotes FuGene
T20258 46775-46776 CD denotes 6
T20259 46777-46789 NN denotes transfection
T20260 46790-46797 NN denotes reagent
T20261 46798-46799 -LRB- denotes (
T20262 46799-46804 NNP denotes Roche
T20263 46804-46805 -COMMA- denotes ,
T20264 46806-46811 NNP denotes Basel
T20265 46811-46812 -COMMA- denotes ,
T20266 46813-46824 NNP denotes Switzerland
T20267 46824-46825 -RRB- denotes )
T20268 46827-46833 NN denotes Jurkat
T20269 46834-46835 NN denotes T
T20270 46836-46841 NN denotes cells
T20271 46842-46846 VB denotes were
T20272 46847-46853 VB denotes plated
T20273 46854-46856 IN denotes at
T20274 46857-46858 CD denotes 1
T20275 46859-46860 NN denotes ×
T20276 46861-46864 CD denotes 106
T20277 46865-46875 NN denotes cells/well
T20278 46876-46878 IN denotes in
T20279 46879-46887 JJ denotes six-well
T20280 46888-46895 NN denotes culture
T20281 46896-46902 VB denotes plates
T20282 46903-46906 DT denotes the
T20283 46907-46910 NN denotes day
T20284 46911-46913 IN denotes of
T20285 46914-46926 NN denotes transfection
T20286 46927-46931 IN denotes with
T20287 46932-46935 DT denotes the
T20288 46936-46947 JJ denotes appropriate
T20289 46948-46955 NN denotes plasmid
T20290 46956-46959 NN denotes DNA
T20291 46960-46961 -LRB- denotes (
T20292 46961-46963 CD denotes ~2
T20293 46964-46966 NN denotes μg
T20294 46967-46972 NN denotes total
T20295 46972-46973 -RRB- denotes )
T20296 46974-46979 VB denotes using
T20297 46980-46986 NN denotes FuGene
T20298 46987-46988 CD denotes 6
T20299 46989-47001 NN denotes transfection
T20300 47002-47009 NN denotes reagent
T20301 47011-47018 JJ denotes Primary
T20302 47019-47024 JJ denotes human
T20303 47025-47029 JJ denotes CD4+
T20304 47030-47031 NN denotes T
T20305 47032-47037 NN denotes cells
T20306 47038-47039 -LRB- denotes (
T20307 47039-47040 CD denotes 2
T20308 47041-47042 CC denotes ×
T20309 47043-47046 CD denotes 106
T20310 47046-47047 -RRB- denotes )
T20311 47048-47052 VB denotes were
T20312 47053-47065 VB denotes nucleofected
T20313 47066-47070 IN denotes with
T20314 47071-47074 DT denotes the
T20315 47075-47084 VB denotes specified
T20316 47085-47092 NN denotes plasmid
T20317 47093-47096 NN denotes DNA
T20318 47097-47098 -LRB- denotes (
T20319 47098-47099 CD denotes 5
T20320 47100-47102 NN denotes μg
T20321 47103-47108 NN denotes total
T20322 47108-47109 -RRB- denotes )
T20323 47110-47115 VB denotes using
T20324 47116-47119 DT denotes the
T20325 47120-47125 JJ denotes Human
T20326 47126-47127 NN denotes T
T20327 47128-47132 NN denotes Cell
T20328 47133-47146 NN denotes Nucleofection
T20329 47147-47150 NN denotes Kit
T20330 47151-47152 -LRB- denotes (
T20331 47152-47157 NNP denotes Amaxa
T20332 47157-47158 -COMMA- denotes ,
T20333 47159-47171 NNP denotes Gaithersburg
T20334 47171-47172 -COMMA- denotes ,
T20335 47173-47181 NNP denotes Maryland
T20336 47181-47182 -COMMA- denotes ,
T20337 47183-47189 NNP denotes United
T20338 47190-47196 NNP denotes States
T20339 47196-47197 -RRB- denotes )
T20340 47199-47208 NN denotes Forskolin
T20341 47209-47210 -LRB- denotes (
T20342 47210-47212 CD denotes 10
T20343 47213-47215 NN denotes μM
T20344 47215-47216 -COLON- denotes ;
T20345 47217-47227 NNP denotes Calbiochem
T20346 47227-47228 -COMMA- denotes ,
T20347 47229-47232 NNP denotes San
T20348 47233-47238 NNP denotes Diego
T20349 47238-47239 -COMMA- denotes ,
T20350 47240-47250 NNP denotes California
T20351 47250-47251 -COMMA- denotes ,
T20352 47252-47258 NNP denotes United
T20353 47259-47265 NNP denotes States
T20354 47265-47266 -RRB- denotes )
T20355 47267-47270 VB denotes was
T20356 47271-47276 VB denotes added
T20357 47277-47279 IN denotes in
T20358 47280-47284 DT denotes some
T20359 47285-47296 NN denotes experiments
T20360 47297-47299 CD denotes 20
T20361 47300-47301 NN denotes h
T20362 47302-47318 NN denotes posttransfection
T20363 47320-47325 NN denotes Cells
T20364 47326-47330 VB denotes were
T20365 47331-47340 VB denotes harvested
T20366 47341-47343 CD denotes 24
T20367 47344-47345 NN denotes h
T20368 47346-47362 NN denotes posttransfection
T20369 47363-47366 CC denotes and
T20370 47367-47377 NN denotes luciferase
T20371 47378-47386 NN denotes activity
T20372 47387-47390 VB denotes was
T20373 47391-47399 VB denotes analyzed
T20374 47400-47405 VB denotes using
T20375 47406-47409 DT denotes the
T20376 47410-47425 NNP denotes Dual-luciferase
T20377 47426-47434 NNP denotes Reporter
T20378 47435-47440 NNP denotes Assay
T20379 47441-47447 NNP denotes System
T20380 47448-47449 -LRB- denotes (
T20381 47449-47456 NNP denotes Promega
T20382 47456-47457 -RRB- denotes )
T20383 47458-47461 CC denotes and
T20384 47462-47463 DT denotes a
T20385 47464-47473 NNP denotes Monolight
T20386 47474-47478 CD denotes 2010
T20387 47479-47490 NN denotes luminometer
T20388 47491-47492 -LRB- denotes (
T20389 47492-47502 NNP denotes Analytical
T20390 47503-47515 NNP denotes Luminescence
T20391 47516-47526 NNP denotes Laboratory
T20392 47526-47527 -COMMA- denotes ,
T20393 47528-47531 NNP denotes San
T20394 47532-47537 NNP denotes Diego
T20395 47537-47538 -COMMA- denotes ,
T20396 47539-47549 NNP denotes California
T20397 47549-47550 -COMMA- denotes ,
T20398 47551-47557 NNP denotes United
T20399 47558-47564 NNP denotes States
T20400 47564-47565 -RRB- denotes )
T20401 47566-47575 VB denotes according
T20402 47576-47578 TO denotes to
T20403 47579-47591 NN denotes manufacturer
T20404 47591-47593 POS denotes 's
T20405 47594-47605 NN denotes guidelines.
T20406 47606-47619 NN denotes pGL4-TKhRluc2
T20407 47620-47623 VB denotes was
T20408 47624-47628 VB denotes used
T20409 47629-47631 IN denotes as
T20410 47632-47634 DT denotes an
T20411 47635-47643 JJ denotes internal
T20412 47644-47651 NN denotes control
T20413 47652-47654 TO denotes to
T20414 47655-47664 VB denotes normalize
T20415 47665-47668 IN denotes for
T20416 47669-47681 NN denotes transfection
T20417 47682-47692 NN denotes efficiency
T20418 47694-47706 VB denotes Nucleofected
T20419 47707-47711 JJ denotes CD4+
T20420 47712-47713 NN denotes T
T20421 47714-47719 NN denotes cells
T20422 47720-47724 VB denotes were
T20423 47725-47729 RB denotes also
T20424 47730-47739 VB denotes monitored
T20425 47740-47743 IN denotes for
T20426 47744-47756 NN denotes transfection
T20427 47757-47767 NN denotes efficiency
T20428 47768-47771 CC denotes and
T20429 47772-47776 NN denotes cell
T20430 47777-47786 NN denotes viability
T20431 47787-47789 CD denotes 24
T20432 47790-47791 NN denotes h
T20433 47792-47808 NN denotes posttransfection
T20434 47809-47811 IN denotes as
T20435 47812-47819 VB denotes follows
T20436 47821-47833 NN denotes Transfection
T20437 47834-47844 NN denotes efficiency
T20438 47845-47848 VB denotes was
T20439 47849-47858 RB denotes routinely
T20440 47859-47862 CD denotes ~30
T20441 47862-47863 NN denotes %
T20442 47864-47866 IN denotes as
T20443 47867-47877 VB denotes determined
T20444 47878-47880 IN denotes by
T20445 47881-47885 NN denotes flow
T20446 47886-47896 JJ denotes cytometric
T20447 47897-47905 NN denotes analysis
T20448 47906-47908 IN denotes of
T20449 47909-47913 NN denotes EGFP
T20450 47914-47924 NN denotes expression
T20451 47926-47930 NN denotes Cell
T20452 47931-47940 NN denotes viability
T20453 47940-47941 -COMMA- denotes ,
T20454 47942-47952 VB denotes determined
T20455 47953-47955 IN denotes by
T20456 47956-47964 VB denotes staining
T20457 47965-47969 IN denotes with
T20458 47970-47989 NN denotes 7-amino-actinomycin
T20459 47990-47991 NN denotes D
T20460 47992-47993 -LRB- denotes (
T20461 47993-47998 NN denotes 7-AAD
T20462 47998-47999 -COLON- denotes ;
T20463 48000-48002 NNP denotes BD
T20464 48003-48014 NNP denotes Biosciences
T20465 48014-48015 -RRB- denotes )
T20466 48015-48016 -COMMA- denotes ,
T20467 48017-48020 VB denotes was
T20468 48021-48030 RB denotes routinely
T20469 48031-48034 CD denotes ~70
T20470 48034-48035 NN denotes %
T20471 48037-48041 CC denotes Both
T20472 48042-48054 NN denotes transfection
T20473 48055-48065 NN denotes efficiency
T20474 48066-48069 CC denotes and
T20475 48070-48074 NN denotes cell
T20476 48075-48084 NN denotes viability
T20477 48085-48087 IN denotes in
T20478 48088-48100 VB denotes nucleofected
T20479 48101-48105 JJ denotes CD4+
T20480 48106-48107 NN denotes T
T20481 48108-48113 NN denotes cells
T20482 48114-48117 VB denotes was
T20483 48118-48129 JJ denotes independent
T20484 48130-48132 IN denotes of
T20485 48133-48136 DT denotes the
T20486 48137-48145 NN denotes plasmids
T20487 48146-48150 VB denotes used
T20807 48153-48158 NN denotes Foxp3
T20808 48159-48162 CC denotes and
T20809 48163-48169 NN denotes HTLV-I
T20810 48170-48173 NN denotes Tax
T20811 48174-48184 NN denotes expression
T20812 48185-48193 NN denotes analysis
T20813 48194-48196 IN denotes by
T20814 48197-48206 JJ denotes real-time
T20815 48207-48213 NN denotes RT-PCR
T20816 48215-48224 JJ denotes Real-time
T20817 48225-48231 NN denotes RT-PCR
T20818 48232-48240 NN denotes analysis
T20819 48241-48243 IN denotes of
T20820 48244-48249 NN denotes Foxp3
T20821 48250-48253 CC denotes and
T20822 48254-48260 NN denotes HTLV-I
T20823 48261-48264 NN denotes Tax
T20824 48265-48275 NN denotes expression
T20825 48276-48279 VB denotes was
T20826 48280-48289 VB denotes performed
T20827 48290-48292 IN denotes as
T20828 48293-48303 RB denotes previously
T20829 48304-48313 VB denotes described
T20830 48314-48315 -LRB- denotes [
T20831 48315-48319 CD denotes 8,47
T20832 48319-48320 -RRB- denotes ]
T20833 48322-48329 RB denotes Briefly
T20834 48329-48330 -COMMA- denotes ,
T20835 48331-48336 JJ denotes total
T20836 48337-48340 NN denotes RNA
T20837 48341-48344 VB denotes was
T20838 48345-48354 VB denotes extracted
T20839 48355-48360 VB denotes using
T20840 48361-48364 DT denotes the
T20841 48365-48371 NNP denotes RNeasy
T20842 48372-48376 NNP denotes Mini
T20843 48377-48380 NNP denotes Kit
T20844 48381-48382 -LRB- denotes (
T20845 48382-48388 NNP denotes Qiagen
T20846 48388-48389 -COMMA- denotes ,
T20847 48390-48398 NNP denotes Valencia
T20848 48398-48399 -COMMA- denotes ,
T20849 48400-48410 NNP denotes California
T20850 48410-48411 -COMMA- denotes ,
T20851 48412-48418 NNP denotes United
T20852 48419-48425 NNP denotes States
T20853 48425-48426 -RRB- denotes )
T20854 48427-48436 VB denotes according
T20855 48437-48439 TO denotes to
T20856 48440-48452 NN denotes manufacturer
T20857 48452-48454 POS denotes 's
T20858 48455-48465 NN denotes guidelines
T20859 48465-48466 -COMMA- denotes ,
T20860 48467-48470 CC denotes and
T20861 48471-48475 NN denotes cDNA
T20862 48476-48479 VB denotes was
T20863 48480-48491 VB denotes synthesized
T20864 48492-48494 IN denotes by
T20865 48495-48502 JJ denotes reverse
T20866 48503-48516 NN denotes transcription
T20867 48517-48522 VB denotes using
T20868 48523-48529 NNP denotes TaqMan
T20869 48530-48534 NNP denotes Gold
T20870 48535-48541 NN denotes RT-PCR
T20871 48542-48545 NN denotes Kit
T20872 48546-48551 VB denotes using
T20873 48552-48558 JJ denotes random
T20874 48559-48566 NN denotes hexamer
T20875 48567-48574 NN denotes primers
T20876 48575-48576 -LRB- denotes (
T20877 48576-48583 NNP denotes Applied
T20878 48584-48594 NNP denotes Biosystems
T20879 48594-48595 -COMMA- denotes ,
T20880 48596-48602 NNP denotes Foster
T20881 48603-48607 NNP denotes City
T20882 48607-48608 -COMMA- denotes ,
T20883 48609-48619 NNP denotes California
T20884 48619-48620 -COMMA- denotes ,
T20885 48621-48627 NNP denotes United
T20886 48628-48634 NNP denotes States
T20887 48634-48635 -RRB- denotes )
T20888 48637-48642 NN denotes Foxp3
T20889 48643-48646 CC denotes and
T20890 48647-48653 NN denotes HTLV-I
T20891 48654-48657 NN denotes Tax
T20892 48658-48662 NN denotes mRNA
T20893 48663-48673 NN denotes expression
T20894 48674-48677 VB denotes was
T20895 48678-48688 VB denotes quantified
T20896 48689-48691 IN denotes by
T20897 48692-48701 JJ denotes real-time
T20898 48702-48705 NN denotes PCR
T20899 48706-48711 VB denotes using
T20900 48712-48715 NNP denotes ABI
T20901 48716-48721 NNP denotes PRISM
T20902 48722-48726 CD denotes 7700
T20903 48727-48735 NNP denotes Sequence
T20904 48736-48745 NN denotes Detection
T20905 48746-48752 NN denotes System
T20906 48753-48754 -LRB- denotes (
T20907 48754-48761 NNP denotes Applied
T20908 48762-48772 NNP denotes Biosystems
T20909 48772-48773 -RRB- denotes )
T20910 48775-48778 DT denotes The
T20911 48779-48789 JJ denotes normalized
T20912 48790-48796 NN denotes values
T20913 48797-48799 IN denotes in
T20914 48800-48804 DT denotes each
T20915 48805-48811 NN denotes sample
T20916 48812-48816 VB denotes were
T20917 48817-48827 VB denotes calculated
T20918 48828-48830 IN denotes as
T20919 48831-48834 DT denotes the
T20920 48835-48843 JJ denotes relative
T20921 48844-48852 NN denotes quantity
T20922 48853-48855 IN denotes of
T20923 48856-48861 NN denotes Foxp3
T20924 48862-48864 CC denotes or
T20925 48865-48871 NN denotes HTLV-I
T20926 48872-48875 NN denotes Tax
T20927 48876-48880 NN denotes mRNA
T20928 48881-48891 NN denotes expression
T20929 48892-48899 VB denotes divided
T20930 48900-48902 IN denotes by
T20931 48903-48906 DT denotes the
T20932 48907-48915 JJ denotes relative
T20933 48916-48924 NN denotes quantity
T20934 48925-48927 IN denotes of
T20935 48928-48932 NN denotes HPRT
T20936 48933-48937 NN denotes mRNA
T20937 48938-48948 NN denotes expression
T20938 48950-48953 DT denotes The
T20939 48954-48960 NN denotes values
T20940 48961-48965 VB denotes were
T20941 48966-48976 VB denotes calculated
T20942 48977-48979 IN denotes by
T20943 48980-48983 DT denotes the
T20944 48984-48993 VB denotes following
T20945 48994-49001 NN denotes formula
T20946 49001-49002 -COLON- denotes :
T20947 49003-49013 VB denotes normalized
T20948 49014-49019 NN denotes Foxp3
T20949 49020-49022 CC denotes or
T20950 49023-49029 NN denotes HTLV-I
T20951 49030-49033 NN denotes Tax
T20952 49034-49044 NN denotes expression
T20953 49045-49046 SYM denotes =
T20954 49047-49050 NN denotes 2Ct
T20955 49051-49056 NN denotes value
T20956 49057-49059 IN denotes of
T20957 49060-49064 NN denotes HPRT
T20958 49065-49066 CC denotes –
T20959 49067-49069 NN denotes Ct
T20960 49070-49075 NN denotes value
T20961 49076-49078 IN denotes of
T20962 49079-49084 NN denotes Foxp3
T20963 49085-49087 CC denotes or
T20964 49088-49094 NN denotes HTLV-I
T20965 49095-49098 NN denotes Tax
T21268 49101-49110 JJ denotes Real-time
T21269 49111-49114 NN denotes PCR
T21270 49116-49125 JJ denotes Real-time
T21271 49126-49129 NN denotes PCR
T21272 49130-49138 NN denotes analysis
T21273 49139-49141 IN denotes of
T21274 49142-49148 NN denotes HTLV-I
T21275 49149-49150 -LRB- denotes (
T21276 49150-49153 NN denotes Tax
T21277 49153-49154 -RRB- denotes )
T21278 49155-49163 JJ denotes proviral
T21279 49164-49168 NN denotes load
T21280 49169-49172 VB denotes was
T21281 49173-49182 VB denotes performed
T21282 49183-49185 IN denotes as
T21283 49186-49196 RB denotes previously
T21284 49197-49206 VB denotes described
T21285 49207-49208 -LRB- denotes [
T21286 49208-49213 CD denotes 47,50
T21287 49213-49214 -RRB- denotes ]
T21288 49216-49219 NN denotes DNA
T21289 49220-49223 VB denotes was
T21290 49224-49233 VB denotes extracted
T21291 49234-49238 IN denotes from
T21292 49239-49240 CD denotes 1
T21293 49241-49242 NN denotes ×
T21294 49243-49246 CD denotes 106
T21295 49247-49252 NN denotes cells
T21296 49253-49258 VB denotes using
T21297 49259-49267 NN denotes Puregene
T21298 49268-49271 NN denotes DNA
T21299 49272-49281 NN denotes Isolation
T21300 49282-49285 NN denotes Kit
T21301 49286-49287 -LRB- denotes (
T21302 49287-49293 NNP denotes Gentra
T21303 49293-49294 -COMMA- denotes ,
T21304 49295-49306 NNP denotes Minneapolis
T21305 49306-49307 -COMMA- denotes ,
T21306 49308-49317 NNP denotes Minnesota
T21307 49317-49318 -COMMA- denotes ,
T21308 49319-49325 NNP denotes United
T21309 49326-49332 NNP denotes States
T21310 49332-49333 -RRB- denotes )
T21311 49333-49334 -COMMA- denotes ,
T21312 49335-49338 CC denotes and
T21313 49339-49342 CD denotes 100
T21314 49343-49345 NN denotes ng
T21315 49346-49348 IN denotes of
T21316 49349-49352 DT denotes the
T21317 49353-49359 NN denotes sample
T21318 49360-49363 NN denotes DNA
T21319 49364-49372 NN denotes solution
T21320 49373-49376 VB denotes was
T21321 49377-49385 VB denotes analyzed
T21322 49386-49388 IN denotes by
T21323 49389-49393 DT denotes this
T21324 49394-49400 NN denotes system
T21325 49402-49405 DT denotes The
T21326 49406-49412 NN denotes HTLV-I
T21327 49413-49421 JJ denotes proviral
T21328 49422-49425 NN denotes DNA
T21329 49426-49430 NN denotes load
T21330 49431-49434 VB denotes was
T21331 49435-49445 VB denotes calculated
T21332 49446-49448 IN denotes by
T21333 49449-49452 DT denotes the
T21334 49453-49462 VB denotes following
T21335 49463-49470 NN denotes formula
T21336 49470-49471 -COLON- denotes :
T21337 49472-49476 NN denotes copy
T21338 49477-49483 NN denotes number
T21339 49484-49486 IN denotes of
T21340 49487-49493 NN denotes HTLV-I
T21341 49494-49495 -LRB- denotes (
T21342 49495-49497 NN denotes pX
T21343 49497-49498 -RRB- denotes )
T21344 49499-49502 IN denotes per
T21345 49503-49506 CD denotes 100
T21346 49507-49512 NN denotes cells
T21347 49513-49514 SYM denotes =
T21348 49515-49516 -LRB- denotes (
T21349 49516-49520 NN denotes copy
T21350 49521-49527 NN denotes number
T21351 49528-49530 IN denotes of
T21352 49531-49533 NN denotes pX
T21353 49533-49534 -RRB- denotes )
T21354 49534-49535 SYM denotes /
T21355 49535-49536 -LRB- denotes (
T21356 49536-49540 NN denotes copy
T21357 49541-49547 NN denotes number
T21358 49548-49550 IN denotes of
T21359 49551-49560 CD denotes β-actin/2
T21360 49560-49561 -RRB- denotes )
T21361 49562-49563 VB denotes ×
T21362 49564-49567 CD denotes 100
T21783 49570-49577 NN denotes Western
T21784 49578-49582 NN denotes blot
T21785 49583-49591 NN denotes analysis
T21786 49593-49596 NN denotes HEK
T21787 49597-49601 NN denotes 293T
T21788 49602-49607 NN denotes cells
T21789 49608-49612 VB denotes were
T21790 49613-49619 VB denotes plated
T21791 49620-49622 IN denotes at
T21792 49623-49624 DT denotes a
T21793 49625-49632 NN denotes density
T21794 49633-49635 IN denotes of
T21795 49636-49637 CD denotes 5
T21796 49638-49639 IN denotes ×
T21797 49640-49643 CD denotes 105
T21798 49644-49654 NN denotes cells/well
T21799 49655-49657 IN denotes in
T21800 49658-49666 JJ denotes six-well
T21801 49667-49674 NN denotes culture
T21802 49675-49681 NN denotes plates
T21803 49682-49683 -LRB- denotes (
T21804 49683-49685 NN denotes BD
T21805 49686-49697 NNP denotes Biosciences
T21806 49697-49698 -RRB- denotes )
T21807 49699-49700 CD denotes 1
T21808 49701-49702 NN denotes d
T21809 49703-49708 JJ denotes prior
T21810 49709-49711 TO denotes to
T21811 49712-49724 NN denotes transfection
T21812 49725-49729 IN denotes with
T21813 49730-49733 DT denotes the
T21814 49734-49745 JJ denotes appropriate
T21815 49746-49753 NN denotes plasmid
T21816 49754-49757 NN denotes DNA
T21817 49758-49759 -LRB- denotes (
T21818 49759-49760 CD denotes 2
T21819 49761-49763 NN denotes μg
T21820 49764-49769 NN denotes total
T21821 49769-49770 -RRB- denotes )
T21822 49771-49776 VB denotes using
T21823 49777-49783 NN denotes FuGene
T21824 49784-49785 CD denotes 6
T21825 49786-49798 NN denotes transfection
T21826 49799-49806 NN denotes reagent
T21827 49807-49808 -LRB- denotes (
T21828 49808-49813 NN denotes Roche
T21829 49813-49814 -RRB- denotes )
T21830 49816-49821 NN denotes Cells
T21831 49822-49826 VB denotes were
T21832 49827-49836 VB denotes harvested
T21833 49837-49839 CD denotes 24
T21834 49840-49841 NN denotes h
T21835 49842-49858 NN denotes posttransfection
T21836 49859-49862 IN denotes for
T21837 49863-49873 JJ denotes whole-cell
T21838 49874-49881 NN denotes lysates
T21839 49882-49884 IN denotes in
T21840 49885-49889 NN denotes RIPA
T21841 49890-49896 NN denotes buffer
T21842 49897-49898 -LRB- denotes (
T21843 49898-49900 CD denotes 50
T21844 49901-49903 NN denotes mM
T21845 49904-49912 NN denotes Tris-HCl
T21846 49913-49914 -LRB- denotes [
T21847 49914-49916 NN denotes pH
T21848 49917-49920 CD denotes 7.4
T21849 49920-49921 -RRB- denotes ]
T21850 49921-49922 -COMMA- denotes ,
T21851 49923-49926 CD denotes 150
T21852 49927-49929 NN denotes mM
T21853 49930-49934 NN denotes NaCl
T21854 49934-49935 -COMMA- denotes ,
T21855 49936-49937 CD denotes 1
T21856 49937-49938 NN denotes %
T21857 49939-49945 NN denotes Igepal
T21858 49946-49947 -LRB- denotes (
T21859 49947-49952 NN denotes NP-40
T21860 49952-49953 -RRB- denotes )
T21861 49953-49954 -COMMA- denotes ,
T21862 49955-49958 CD denotes 0.5
T21863 49958-49959 NN denotes %
T21864 49960-49966 NN denotes sodium
T21865 49967-49979 NN denotes deoxycholate
T21866 49979-49980 -COMMA- denotes ,
T21867 49981-49982 CD denotes 1
T21868 49983-49985 NN denotes mM
T21869 49986-49990 NN denotes EDTA
T21870 49990-49991 -COMMA- denotes ,
T21871 49992-49993 CD denotes 1
T21872 49994-49996 NN denotes mM
T21873 49997-50000 NN denotes DTT
T21874 50000-50001 -COMMA- denotes ,
T21875 50002-50003 CD denotes 1
T21876 50004-50006 NN denotes mM
T21877 50007-50011 NN denotes PMSF
T21878 50011-50012 -COMMA- denotes ,
T21879 50013-50016 CC denotes and
T21880 50017-50019 CD denotes 1×
T21881 50020-50028 NNP denotes Complete
T21882 50029-50033 NNP denotes Mini
T21883 50034-50042 NNP denotes Protease
T21884 50043-50052 NNP denotes Inhibitor
T21885 50053-50054 -LRB- denotes [
T21886 50054-50059 NNP denotes Roche
T21887 50059-50060 -RRB- denotes ]
T21888 50060-50061 -RRB- denotes )
T21889 50063-50070 NN denotes Protein
T21890 50071-50084 NN denotes concentration
T21891 50085-50088 VB denotes was
T21892 50089-50099 VB denotes determined
T21893 50100-50102 IN denotes by
T21894 50103-50108 NN denotes Lowry
T21895 50109-50114 NN denotes assay
T21896 50115-50116 -LRB- denotes (
T21897 50116-50123 NNP denotes Bio-Rad
T21898 50123-50124 -COMMA- denotes ,
T21899 50125-50133 NNP denotes Hercules
T21900 50133-50134 -COMMA- denotes ,
T21901 50135-50145 NNP denotes California
T21902 50145-50146 -COMMA- denotes ,
T21903 50147-50153 NNP denotes United
T21904 50154-50160 NNP denotes States
T21905 50160-50161 -RRB- denotes )
T21906 50162-50165 CC denotes and
T21907 50166-50178 JJ denotes colorimetric
T21908 50179-50188 NN denotes reactions
T21909 50189-50193 VB denotes were
T21910 50194-50198 VB denotes read
T21911 50199-50204 VB denotes using
T21912 50205-50206 DT denotes a
T21913 50207-50215 NN denotes VersaMax
T21914 50216-50226 NN denotes microplate
T21915 50227-50233 NN denotes reader
T21916 50234-50235 -LRB- denotes (
T21917 50235-50244 NNP denotes Molecular
T21918 50245-50252 NNP denotes Devices
T21919 50252-50253 -COMMA- denotes ,
T21920 50254-50263 NNP denotes Sunnyvale
T21921 50263-50264 -COMMA- denotes ,
T21922 50265-50275 NNP denotes California
T21923 50275-50276 -COMMA- denotes ,
T21924 50277-50283 NNP denotes United
T21925 50284-50290 NNP denotes States
T21926 50290-50291 -RRB- denotes )
T21927 50292-50294 IN denotes at
T21928 50295-50297 DT denotes an
T21929 50298-50308 NN denotes absorbance
T21930 50309-50311 IN denotes of
T21931 50312-50315 CD denotes 750
T21932 50316-50318 NN denotes nm
T21933 50320-50324 NN denotes Size
T21934 50325-50338 NN denotes fractionation
T21935 50339-50342 VB denotes was
T21936 50343-50352 VB denotes performed
T21937 50353-50355 IN denotes on
T21938 50356-50358 CD denotes 20
T21939 50359-50361 NN denotes μg
T21940 50362-50364 IN denotes of
T21941 50365-50379 NN denotes protein/sample
T21942 50380-50382 IN denotes by
T21943 50383-50391 NN denotes SDS-PAGE
T21944 50391-50392 -COMMA- denotes ,
T21945 50393-50396 CC denotes and
T21946 50397-50400 DT denotes the
T21947 50401-50408 NN denotes protein
T21948 50409-50412 VB denotes was
T21949 50413-50424 VB denotes transferred
T21950 50425-50427 TO denotes to
T21951 50428-50442 NN denotes nitrocellulose
T21952 50443-50445 CC denotes or
T21953 50446-50450 NN denotes PVDF
T21954 50451-50460 NN denotes membranes
T21955 50461-50464 CC denotes and
T21956 50465-50474 VB denotes subjected
T21957 50475-50477 TO denotes to
T21958 50478-50492 NN denotes immunoblotting
T21959 50493-50498 VB denotes using
T21960 50499-50502 DT denotes the
T21961 50503-50512 JJ denotes indicated
T21962 50513-50523 NN denotes antibodies
T21963 50525-50530 NN denotes Foxp3
T21964 50531-50534 VB denotes was
T21965 50535-50543 VB denotes detected
T21966 50544-50549 VB denotes using
T21967 50550-50556 NN denotes rabbit
T21968 50557-50567 JJ denotes anti-human
T21969 50568-50573 NN denotes Foxp3
T21970 50574-50584 JJ denotes polyclonal
T21971 50585-50593 NN denotes antibody
T21972 50594-50595 -LRB- denotes (
T21973 50595-50601 NN denotes ab4728
T21974 50602-50604 CC denotes or
T21975 50605-50612 NN denotes ab10563
T21976 50612-50613 -COLON- denotes ;
T21977 50614-50619 NNP denotes Abcam
T21978 50619-50620 -COMMA- denotes ,
T21979 50621-50630 NNP denotes Cambridge
T21980 50630-50631 -COMMA- denotes ,
T21981 50632-50638 NNP denotes United
T21982 50639-50646 NNP denotes Kingdom
T21983 50646-50647 -RRB- denotes )
T21984 50648-50651 CC denotes and
T21985 50652-50663 JJ denotes anti-rabbit
T21986 50664-50671 NN denotes IgG-HRP
T21987 50672-50681 JJ denotes secondary
T21988 50682-50690 NN denotes antibody
T21989 50691-50692 -LRB- denotes (
T21990 50692-50696 NNP denotes Cell
T21991 50697-50706 NNP denotes Signaling
T21992 50707-50717 NNP denotes Technology
T21993 50717-50718 -COMMA- denotes ,
T21994 50719-50726 NNP denotes Beverly
T21995 50726-50727 -COMMA- denotes ,
T21996 50728-50741 NNP denotes Massachusetts
T21997 50741-50742 -COMMA- denotes ,
T21998 50743-50749 NNP denotes United
T21999 50750-50756 NNP denotes States
T22000 50756-50757 -RRB- denotes )
T22001 50759-50764 NN denotes NF-κB
T22002 50765-50768 NN denotes p65
T22003 50769-50772 CC denotes and
T22004 50773-50779 NN denotes CREB-1
T22005 50780-50784 VB denotes were
T22006 50785-50793 VB denotes detected
T22007 50794-50799 VB denotes using
T22008 50800-50806 NN denotes rabbit
T22009 50807-50817 JJ denotes anti-human
T22010 50818-50828 JJ denotes polyclonal
T22011 50829-50830 -LRB- denotes (
T22012 50830-50833 NN denotes p65
T22013 50833-50834 -RRB- denotes )
T22014 50835-50837 CC denotes or
T22015 50838-50848 JJ denotes monoclonal
T22016 50849-50857 NN denotes antibody
T22017 50858-50859 -LRB- denotes (
T22018 50859-50865 NN denotes CREB-1
T22019 50865-50866 -COLON- denotes ;
T22020 50867-50871 NN denotes 48H2
T22021 50871-50872 -RRB- denotes )
T22022 50873-50874 -LRB- denotes (
T22023 50874-50878 NNP denotes Cell
T22024 50879-50888 NNP denotes Signaling
T22025 50889-50899 NNP denotes Technology
T22026 50899-50900 -RRB- denotes )
T22027 50902-50912 NN denotes Beta-actin
T22028 50913-50916 VB denotes was
T22029 50917-50925 VB denotes detected
T22030 50926-50931 VB denotes using
T22031 50932-50933 DT denotes a
T22032 50934-50939 NN denotes mouse
T22033 50940-50950 JJ denotes monoclonal
T22034 50951-50959 NN denotes antibody
T22035 50960-50961 -LRB- denotes (
T22036 50961-50966 NN denotes AC-15
T22037 50966-50967 -COLON- denotes ;
T22038 50968-50973 NNP denotes Sigma
T22039 50973-50974 -COMMA- denotes ,
T22040 50975-50978 NNP denotes St.
T22041 50979-50984 NNP denotes Louis
T22042 50984-50985 -COMMA- denotes ,
T22043 50986-50994 NNP denotes Missouri
T22044 50994-50995 -COMMA- denotes ,
T22045 50996-51002 NNP denotes United
T22046 51003-51009 NNP denotes States
T22047 51009-51010 -RRB- denotes )
T22048 51012-51015 IN denotes For
T22049 51016-51037 NN denotes coimmunoprecipitation
T22050 51038-51046 NN denotes analysis
T22051 51046-51047 -COMMA- denotes ,
T22052 51048-51052 NN denotes cell
T22053 51053-51060 NN denotes lysates
T22054 51061-51065 VB denotes were
T22055 51066-51076 VB denotes precleared
T22056 51077-51081 IN denotes with
T22057 51082-51084 CD denotes 30
T22058 51085-51087 NN denotes μl
T22059 51088-51090 IN denotes of
T22060 51091-51098 NN denotes protein
T22061 51099-51102 NN denotes A/G
T22062 51103-51115 JJ denotes plus-agarose
T22063 51116-51121 NN denotes beads
T22064 51122-51123 -LRB- denotes (
T22065 51123-51128 NNP denotes Santa
T22066 51129-51133 NNP denotes Cruz
T22067 51134-51147 NNP denotes Biotechnology
T22068 51147-51148 -COMMA- denotes ,
T22069 51149-51154 NNP denotes Santa
T22070 51155-51159 NNP denotes Cruz
T22071 51159-51160 -COMMA- denotes ,
T22072 51161-51171 NNP denotes California
T22073 51171-51172 -COMMA- denotes ,
T22074 51173-51179 NNP denotes United
T22075 51180-51186 NNP denotes States
T22076 51186-51187 -RRB- denotes )
T22077 51188-51191 CC denotes and
T22078 51192-51196 RB denotes then
T22079 51197-51206 VB denotes incubated
T22080 51207-51211 IN denotes with
T22081 51212-51217 NN denotes mouse
T22082 51218-51228 JJ denotes monoclonal
T22083 51229-51236 JJ denotes anti-HA
T22084 51237-51245 NN denotes antibody
T22085 51246-51247 -LRB- denotes (
T22086 51247-51250 NN denotes 6E2
T22087 51250-51251 -COLON- denotes ;
T22088 51252-51253 CD denotes 1
T22089 51253-51254 -COLON- denotes :
T22090 51254-51257 CD denotes 100
T22091 51257-51258 -COLON- denotes ;
T22092 51259-51263 NNP denotes Cell
T22093 51264-51273 NNP denotes Signaling
T22094 51274-51284 NNP denotes Technology
T22095 51284-51285 -RRB- denotes )
T22096 51286-51289 CC denotes and
T22097 51290-51292 CD denotes 30
T22098 51293-51295 NN denotes μl
T22099 51296-51298 IN denotes of
T22100 51299-51306 NN denotes protein
T22101 51307-51310 NN denotes A/G
T22102 51311-51323 JJ denotes plus-agarose
T22103 51324-51329 NN denotes beads
T22104 51330-51339 RB denotes overnight
T22105 51341-51344 DT denotes The
T22106 51345-51363 NN denotes immunoprecipitates
T22107 51364-51368 VB denotes were
T22108 51369-51375 VB denotes washed
T22109 51376-51380 CD denotes four
T22110 51381-51386 NN denotes times
T22111 51387-51391 IN denotes with
T22112 51392-51396 NN denotes RIPA
T22113 51397-51403 NN denotes buffer
T22114 51403-51404 -COMMA- denotes ,
T22115 51405-51416 VB denotes resuspended
T22116 51417-51419 IN denotes in
T22117 51420-51423 NN denotes SDS
T22118 51424-51430 NN denotes sample
T22119 51431-51437 NN denotes buffer
T22120 51437-51438 -COMMA- denotes ,
T22121 51439-51442 CC denotes and
T22122 51443-51449 VB denotes heated
T22123 51450-51452 IN denotes at
T22124 51453-51455 CD denotes 95
T22125 51456-51458 NN denotes °C
T22126 51459-51462 IN denotes for
T22127 51463-51464 CD denotes 5
T22128 51465-51468 NN denotes min
T22129 51470-51478 NN denotes Proteins
T22130 51479-51483 VB denotes were
T22131 51484-51488 RB denotes then
T22132 51489-51496 VB denotes treated
T22133 51497-51499 IN denotes as
T22134 51500-51509 VB denotes described
T22135 51510-51513 IN denotes for
T22136 51514-51521 JJ denotes Western
T22137 51522-51526 NN denotes blot
T22138 51527-51535 NN denotes analysis
T22446 51538-51551 NN denotes Transcription
T22447 51552-51558 NN denotes factor
T22448 51559-51570 JJ denotes DNA-binding
T22449 51571-51579 NN denotes analysis
T22450 51580-51581 -LRB- denotes (
T22451 51581-51589 NN denotes TF-ELISA
T22452 51589-51590 -RRB- denotes )
T22453 51592-51598 NN denotes CREB-1
T22454 51599-51602 CC denotes and
T22455 51603-51608 NN denotes ATF-2
T22456 51609-51620 JJ denotes DNA-binding
T22457 51621-51629 NN denotes activity
T22458 51630-51633 VB denotes was
T22459 51634-51642 VB denotes analyzed
T22460 51643-51647 IN denotes with
T22461 51648-51651 DT denotes the
T22462 51652-51663 NN denotes TransFactor
T22463 51664-51673 NN denotes Profiling
T22464 51674-51675 -LRB- denotes (
T22465 51675-51687 NN denotes Inflammation
T22466 51688-51689 CD denotes 1
T22467 51689-51690 -RRB- denotes )
T22468 51691-51694 NN denotes Kit
T22469 51695-51696 -LRB- denotes (
T22470 51696-51698 NN denotes BD
T22471 51699-51710 NNP denotes Biosciences
T22472 51710-51711 -RRB- denotes )
T22473 51712-51721 VB denotes according
T22474 51722-51724 TO denotes to
T22475 51725-51728 DT denotes the
T22476 51729-51741 NN denotes manufacturer
T22477 51741-51743 POS denotes 's
T22478 51744-51752 NN denotes protocol
T22479 51754-51761 JJ denotes Nuclear
T22480 51762-51770 NN denotes extracts
T22481 51771-51775 VB denotes were
T22482 51776-51784 VB denotes prepared
T22483 51785-51789 IN denotes from
T22484 51790-51793 NN denotes HEK
T22485 51794-51798 NN denotes 293T
T22486 51799-51804 NN denotes cells
T22487 51805-51816 VB denotes transfected
T22488 51817-51821 IN denotes with
T22489 51822-51823 DT denotes a
T22490 51824-51831 NN denotes control
T22491 51832-51838 NN denotes vector
T22492 51839-51840 -LRB- denotes (
T22493 51840-51844 NN denotes EGFP
T22494 51844-51845 -RRB- denotes )
T22495 51846-51848 CC denotes or
T22496 51849-51854 NN denotes Foxp3
T22497 51855-51865 NN denotes expression
T22498 51866-51872 NN denotes vector
T22499 51873-51874 -LRB- denotes (
T22500 51874-51879 CD denotes 1,000
T22501 51880-51882 NN denotes ng
T22502 51882-51883 -RRB- denotes )
T22503 51884-51886 IN denotes in
T22504 51887-51890 DT denotes the
T22505 51891-51899 NN denotes presence
T22506 51900-51902 CC denotes or
T22507 51903-51910 NN denotes absence
T22508 51911-51913 IN denotes of
T22509 51914-51923 NN denotes forskolin
T22510 51924-51925 -LRB- denotes (
T22511 51925-51927 CD denotes 10
T22512 51928-51930 NN denotes μM
T22513 51931-51934 IN denotes for
T22514 51935-51936 CD denotes 4
T22515 51937-51938 NN denotes h
T22516 51938-51939 -RRB- denotes )
T22517 51940-51945 VB denotes using
T22518 51946-51949 DT denotes the
T22519 51950-51961 NNP denotes TransFactor
T22520 51962-51972 NN denotes Extraction
T22521 51973-51976 NN denotes Kit
T22522 51977-51978 -LRB- denotes (
T22523 51978-51980 NN denotes BD
T22524 51981-51992 NNP denotes Biosciences
T22525 51992-51993 -RRB- denotes )
T22526 51995-52002 NN denotes Protein
T22527 52003-52016 NN denotes concentration
T22528 52017-52020 VB denotes was
T22529 52021-52031 VB denotes determined
T22530 52032-52037 VB denotes using
T22531 52038-52039 DT denotes a
T22532 52040-52053 NNP denotes Biophotometer
T22533 52054-52055 -LRB- denotes (
T22534 52055-52064 NNP denotes Eppendorf
T22535 52064-52065 -COMMA- denotes ,
T22536 52066-52073 NNP denotes Hamburg
T22537 52073-52074 -COMMA- denotes ,
T22538 52075-52082 NNP denotes Germany
T22539 52082-52083 -RRB- denotes )
T22540 52085-52092 JJ denotes Nuclear
T22541 52093-52101 NN denotes extracts
T22542 52102-52103 -LRB- denotes (
T22543 52103-52105 CD denotes 20
T22544 52106-52108 NN denotes μg
T22545 52108-52109 -RRB- denotes )
T22546 52110-52114 VB denotes were
T22547 52115-52124 VB denotes incubated
T22548 52125-52127 IN denotes in
T22549 52128-52138 VB denotes preblocked
T22550 52139-52144 NN denotes wells
T22551 52145-52155 VB denotes containing
T22552 52156-52167 JJ denotes plate-bound
T22553 52168-52183 JJ denotes double-stranded
T22554 52184-52200 NN denotes oligonucleotides
T22555 52201-52214 VB denotes corresponding
T22556 52215-52217 TO denotes to
T22557 52218-52220 DT denotes an
T22558 52221-52229 NN denotes ATF/CREB
T22559 52230-52239 NN denotes consensus
T22560 52240-52248 NN denotes sequence
T22561 52249-52250 -LRB- denotes (
T22562 52250-52260 NN denotes …TGACATCA…
T22563 52260-52261 -RRB- denotes )
T22564 52263-52268 NN denotes Wells
T22565 52269-52273 VB denotes were
T22566 52274-52280 VB denotes washed
T22567 52280-52281 -COMMA- denotes ,
T22568 52282-52291 VB denotes incubated
T22569 52292-52296 IN denotes with
T22570 52297-52300 DT denotes the
T22571 52301-52312 JJ denotes appropriate
T22572 52313-52320 JJ denotes primary
T22573 52321-52329 NN denotes antibody
T22574 52329-52330 -COMMA- denotes ,
T22575 52331-52337 VB denotes washed
T22576 52337-52338 -COMMA- denotes ,
T22577 52339-52348 VB denotes incubated
T22578 52349-52353 IN denotes with
T22579 52354-52363 JJ denotes secondary
T22580 52364-52372 NN denotes antibody
T22581 52373-52374 -LRB- denotes (
T22582 52374-52385 JJ denotes HRP-labeled
T22583 52385-52386 -RRB- denotes )
T22584 52386-52387 -COMMA- denotes ,
T22585 52388-52394 VB denotes washed
T22586 52395-52400 RB denotes again
T22587 52400-52401 -COMMA- denotes ,
T22588 52402-52405 CC denotes and
T22589 52406-52413 RB denotes finally
T22590 52414-52423 VB denotes developed
T22591 52424-52428 IN denotes with
T22592 52429-52432 NN denotes TMB
T22593 52433-52442 NN denotes substrate
T22594 52444-52456 JJ denotes Colorimetric
T22595 52457-52466 NN denotes reactions
T22596 52467-52471 VB denotes were
T22597 52472-52476 VB denotes read
T22598 52477-52482 VB denotes using
T22599 52483-52484 DT denotes a
T22600 52485-52493 NN denotes VersaMax
T22601 52494-52504 NN denotes microplate
T22602 52505-52511 NN denotes reader
T22603 52512-52513 -LRB- denotes (
T22604 52513-52522 NNP denotes Molecular
T22605 52523-52530 NNP denotes Devices
T22606 52530-52531 -RRB- denotes )
T22607 52532-52534 IN denotes at
T22608 52535-52537 DT denotes an
T22609 52538-52548 NN denotes absorbance
T22610 52549-52551 IN denotes of
T22611 52552-52555 CD denotes 655
T22612 52556-52558 NN denotes nm
T22962 52561-52565 NN denotes Flow
T22963 52566-52576 JJ denotes cytometric
T22964 52577-52585 NN denotes analysis
T22965 52586-52588 IN denotes of
T22966 52589-52594 NN denotes Foxp3
T22967 52595-52602 NN denotes protein
T22968 52603-52613 NN denotes expression
T22969 52615-52628 VB denotes Cryopreserved
T22970 52629-52634 NN denotes PBMCs
T22971 52635-52639 IN denotes from
T22972 52640-52647 NN denotes HAM/TSP
T22973 52648-52656 NN denotes patients
T22974 52657-52659 CC denotes or
T22975 52660-52675 JJ denotes HTLV-I-infected
T22976 52676-52679 NN denotes ACs
T22977 52680-52684 VB denotes were
T22978 52685-52691 VB denotes thawed
T22979 52692-52695 CC denotes and
T22980 52696-52702 VB denotes washed
T22981 52703-52707 IN denotes with
T22982 52708-52712 NN denotes FACS
T22983 52713-52719 NN denotes buffer
T22984 52720-52721 -LRB- denotes (
T22985 52721-52723 CD denotes 1×
T22986 52724-52727 NNP denotes PBS
T22987 52727-52728 -COMMA- denotes ,
T22988 52729-52732 CD denotes 0.1
T22989 52732-52733 NN denotes %
T22990 52734-52738 NN denotes NaN3
T22991 52738-52739 -COMMA- denotes ,
T22992 52740-52741 CD denotes 5
T22993 52741-52742 NN denotes %
T22994 52743-52746 NN denotes FBS
T22995 52746-52747 -RRB- denotes )
T22996 52749-52754 NN denotes Cells
T22997 52755-52756 -LRB- denotes (
T22998 52756-52759 CD denotes 1.5
T22999 52760-52761 CC denotes ×
T23000 52762-52765 CD denotes 106
T23001 52765-52766 -RRB- denotes )
T23002 52767-52771 VB denotes were
T23003 52772-52777 VB denotes fixed
T23004 52778-52780 IN denotes by
T23005 52781-52791 JJ denotes sequential
T23006 52792-52813 NN denotes formaldehyde/methanol
T23007 52814-52822 NN denotes fixation
T23008 52823-52825 IN denotes as
T23009 52826-52833 VB denotes follows
T23010 52835-52840 NN denotes Cells
T23011 52841-52845 VB denotes were
T23012 52846-52855 RB denotes carefully
T23013 52856-52867 VB denotes resuspended
T23014 52868-52870 IN denotes in
T23015 52871-52875 NN denotes FACS
T23016 52876-52882 NN denotes buffer
T23017 52883-52886 CC denotes and
T23018 52887-52892 VB denotes fixed
T23019 52893-52897 IN denotes with
T23020 52898-52901 CD denotes 100
T23021 52902-52904 NN denotes μl
T23022 52905-52907 IN denotes of
T23023 52908-52915 NN denotes reagent
T23024 52916-52917 NN denotes A
T23025 52918-52919 -LRB- denotes (
T23026 52919-52922 NNP denotes Fix
T23027 52923-52924 CC denotes &
T23028 52925-52929 NNP denotes Perm
T23029 52930-52933 NN denotes kit
T23030 52933-52934 -COLON- denotes ;
T23031 52935-52941 NNP denotes Caltag
T23032 52942-52954 NNP denotes Laboratories
T23033 52954-52955 -COMMA- denotes ,
T23034 52956-52966 NNP denotes Burlingame
T23035 52966-52967 -COMMA- denotes ,
T23036 52968-52978 NNP denotes California
T23037 52978-52979 -COMMA- denotes ,
T23038 52980-52986 NNP denotes United
T23039 52987-52993 NNP denotes States
T23040 52993-52994 -RRB- denotes )
T23041 52995-52997 IN denotes at
T23042 52998-53002 NN denotes room
T23043 53003-53014 NN denotes temperature
T23044 53015-53018 IN denotes for
T23045 53019-53020 CD denotes 3
T23046 53021-53024 NN denotes min
T23047 53025-53033 VB denotes followed
T23048 53034-53036 IN denotes by
T23049 53037-53038 CD denotes 2
T23050 53039-53041 NN denotes ml
T23051 53042-53044 IN denotes of
T23052 53045-53047 CD denotes 70
T23053 53047-53048 NN denotes %
T23054 53049-53057 NN denotes methanol
T23055 53058-53061 IN denotes for
T23056 53062-53063 CD denotes 5
T23057 53064-53067 NN denotes min
T23058 53068-53070 IN denotes at
T23059 53071-53072 CD denotes 4
T23060 53073-53076 NNP denotes °C.
T23061 53077-53082 NNP denotes Cells
T23062 53083-53087 VB denotes were
T23063 53088-53094 VB denotes washed
T23064 53095-53100 RB denotes twice
T23065 53101-53104 CC denotes and
T23066 53105-53118 VB denotes permeabilized
T23067 53119-53123 IN denotes with
T23068 53124-53127 CD denotes 100
T23069 53128-53130 NN denotes μl
T23070 53131-53133 IN denotes of
T23071 53134-53141 NN denotes reagent
T23072 53142-53143 NN denotes B
T23073 53144-53145 -LRB- denotes (
T23074 53145-53148 NNP denotes Fix
T23075 53149-53150 CC denotes &
T23076 53151-53155 NNP denotes Perm
T23077 53156-53159 NN denotes kit
T23078 53159-53160 -RRB- denotes )
T23079 53161-53164 CC denotes and
T23080 53165-53172 VB denotes stained
T23081 53173-53176 IN denotes for
T23082 53177-53190 JJ denotes intracellular
T23083 53191-53196 NN denotes Foxp3
T23084 53197-53201 IN denotes with
T23085 53202-53207 NN denotes mouse
T23086 53208-53218 JJ denotes anti-human
T23087 53219-53224 NN denotes Foxp3
T23088 53225-53235 JJ denotes monoclonal
T23089 53236-53244 NN denotes antibody
T23090 53245-53246 -LRB- denotes (
T23091 53246-53249 CD denotes 0.5
T23092 53250-53252 NN denotes μg
T23093 53253-53255 IN denotes of
T23094 53256-53263 NN denotes ab22510
T23095 53263-53264 -COLON- denotes ;
T23096 53265-53270 NN denotes Abcam
T23097 53270-53271 -RRB- denotes )
T23098 53272-53274 CC denotes or
T23099 53275-53278 DT denotes the
T23100 53279-53290 JJ denotes appropriate
T23101 53291-53298 NN denotes isotype
T23102 53299-53306 NN denotes control
T23103 53307-53310 IN denotes for
T23104 53311-53313 CD denotes 30
T23105 53314-53317 NN denotes min
T23106 53319-53324 NN denotes Cells
T23107 53325-53329 VB denotes were
T23108 53330-53336 VB denotes washed
T23109 53337-53342 RB denotes twice
T23110 53343-53346 CC denotes and
T23111 53347-53354 VB denotes stained
T23112 53355-53359 IN denotes with
T23113 53360-53374 JJ denotes Cy5-conjugated
T23114 53375-53379 NN denotes goat
T23115 53380-53390 JJ denotes anti-mouse
T23116 53391-53405 NN denotes immunoglobulin
T23117 53406-53407 NN denotes F
T23118 53407-53408 -LRB- denotes (
T23119 53408-53411 NN denotes ab′
T23120 53411-53412 -RRB- denotes )
T23121 53412-53413 CD denotes 2
T23122 53414-53423 JJ denotes secondary
T23123 53424-53432 NN denotes antibody
T23124 53433-53434 -LRB- denotes (
T23125 53434-53440 NNP denotes Caltag
T23126 53441-53453 NNP denotes Laboratories
T23127 53453-53454 -RRB- denotes )
T23128 53455-53458 IN denotes for
T23129 53459-53461 DT denotes an
T23130 53462-53472 JJ denotes additional
T23131 53473-53475 CD denotes 30
T23132 53476-53479 NN denotes min
T23133 53481-53486 NN denotes Cells
T23134 53487-53491 VB denotes were
T23135 53492-53498 VB denotes washed
T23136 53499-53504 RB denotes twice
T23137 53505-53508 CC denotes and
T23138 53509-53516 VB denotes stained
T23139 53517-53520 IN denotes for
T23140 53521-53528 NN denotes surface
T23141 53529-53532 NN denotes CD4
T23142 53533-53543 NN denotes expression
T23143 53544-53548 IN denotes with
T23144 53549-53559 JJ denotes PE-labeled
T23145 53560-53568 NN denotes anti-CD4
T23146 53569-53570 -LRB- denotes (
T23147 53570-53572 NN denotes BD
T23148 53572-53573 -RRB- denotes )
T23149 53574-53577 CC denotes and
T23150 53578-53582 NN denotes CD25
T23151 53583-53593 NN denotes expression
T23152 53594-53598 IN denotes with
T23153 53599-53611 JJ denotes FITC-labeled
T23154 53612-53621 NN denotes anti-CD25
T23155 53622-53623 -LRB- denotes (
T23156 53623-53625 NN denotes BD
T23157 53625-53626 -RRB- denotes )
T23158 53628-53633 NN denotes Cells
T23159 53634-53638 VB denotes were
T23160 53639-53645 VB denotes washed
T23161 53646-53651 RB denotes twice
T23162 53652-53655 CC denotes and
T23163 53656-53664 VB denotes analyzed
T23164 53665-53667 IN denotes on
T23165 53668-53669 DT denotes a
T23166 53670-53681 NNP denotes FACSCalibur
T23167 53682-53683 -LRB- denotes (
T23168 53683-53685 NN denotes BD
T23169 53685-53686 -RRB- denotes )
T23170 53688-53692 NN denotes Data
T23171 53693-53701 NN denotes analysis
T23172 53702-53705 VB denotes was
T23173 53706-53715 VB denotes performed
T23174 53716-53721 VB denotes using
T23175 53722-53728 NNP denotes FlowJo
T23176 53729-53730 -LRB- denotes (
T23177 53730-53734 NNP denotes Tree
T23178 53735-53739 NNP denotes Star
T23179 53739-53740 -COMMA- denotes ,
T23180 53741-53748 NNP denotes Ashland
T23181 53748-53749 -COMMA- denotes ,
T23182 53750-53756 NNP denotes Oregon
T23183 53756-53757 -COMMA- denotes ,
T23184 53758-53764 NNP denotes United
T23185 53765-53771 NNP denotes States
T23186 53771-53772 -RRB- denotes )
T23298 53775-53786 JJ denotes Statistical
T23299 53787-53795 NN denotes analyses
T23300 53797-53800 DT denotes The
T23301 53801-53813 NNP denotes Mann-Whitney
T23302 53814-53815 NNP denotes U
T23303 53816-53820 NN denotes test
T23304 53821-53824 VB denotes was
T23305 53825-53829 VB denotes used
T23306 53830-53832 TO denotes to
T23307 53833-53840 VB denotes compare
T23308 53841-53844 DT denotes the
T23309 53845-53849 NN denotes data
T23310 53850-53857 IN denotes between
T23311 53858-53866 NN denotes patients
T23312 53867-53871 IN denotes with
T23313 53872-53879 NN denotes HAM/TSP
T23314 53880-53883 CC denotes and
T23315 53884-53886 NN denotes AC
R10000 T13133 T13134 arg1Of transcription,of
R10001 T13138 T13134 arg2Of protein,of
R10002 T13138 T13135 arg1Of protein,the
R10003 T13138 T13136 arg1Of protein,Gal4-BD-CREB-1
R10004 T13138 T13137 arg1Of protein,fusion
R10005 T13139 T13143 arg1Of Foxp3,repressed
R10006 T13139 T13156 arg1Of Foxp3,neutralizing
R10007 T13143 T13140 arg1Of repressed,","
R10008 T13143 T13141 arg1Of repressed,again
R10009 T13143 T13142 arg1Of repressed,","
R10010 T13143 T13149 arg1Of repressed,by
R10011 T13143 T13153 arg1Of repressed,","
R10012 T13143 T13154 arg1Of repressed,while
R10013 T13145 T13143 arg2Of levels,repressed
R10014 T13145 T13144 arg1Of levels,basal
R10015 T13145 T13146 arg1Of levels,of
R10016 T13148 T13146 arg2Of activation,of
R10017 T13148 T13147 arg1Of activation,Gal4-BD-CREB-1
R10018 T13150 T13149 arg2Of more,by
R10019 T13150 T13151 arg1Of more,than
R10020 T13152 T13151 arg2Of 2-fold,than
R10021 T13156 T13154 arg2Of neutralizing,while
R10022 T13156 T13155 arg1Of neutralizing,effectively
R10023 T13158 T13156 arg2Of activation,neutralizing
R10024 T13158 T13157 arg1Of activation,Gal4-BD-CREB-1
R10025 T13158 T13159 arg1Of activation,in
R10026 T13161 T13159 arg2Of presence,in
R10027 T13161 T13160 arg1Of presence,the
R10028 T13161 T13162 arg1Of presence,of
R10029 T13163 T13162 arg2Of p300,of
R10030 T13164 T13166 arg1Of We,analyzed
R10031 T13166 T13165 arg1Of analyzed,next
R10032 T13168 T13166 arg2Of effect,analyzed
R10033 T13168 T13167 arg1Of effect,the
R10034 T13168 T13169 arg1Of effect,of
R10035 T13168 T13171 arg1Of effect,on
R10036 T13170 T13169 arg2Of Foxp3,of
R10037 T13172 T13171 arg2Of phosphorylation,on
R10038 T13172 T13173 arg1Of phosphorylation,of
R10039 T13172 T13175 arg1Of phosphorylation,at
R10040 T13172 T13183 arg1Of phosphorylation,by
R10041 T13174 T13173 arg2Of CREB,of
R10042 T13176 T13175 arg2Of serine,at
R10043 T13176 T13177 arg1Of serine,133
R10044 T13176 T13178 arg1Of serine,in
R10045 T13182 T13178 arg2Of cells,in
R10046 T13182 T13179 arg1Of cells,forskolin-treated
R10047 T13182 T13180 arg1Of cells,HEK
R10048 T13182 T13181 arg1Of cells,293T
R10049 T13186 T13183 arg2Of analysis,by
R10050 T13186 T13184 arg1Of analysis,Western
R10051 T13186 T13185 arg1Of analysis,blot
R10052 T13187 T13188 arg1Of Overexpression,of
R10053 T13187 T13190 arg1Of Overexpression,failed
R10054 T13187 T13192 arg1Of Overexpression,reduce
R10055 T13189 T13188 arg2Of Foxp3,of
R10056 T13192 T13190 arg2Of reduce,failed
R10057 T13192 T13191 arg1Of reduce,to
R10058 T13195 T13192 arg2Of levels,reduce
R10059 T13195 T13193 arg1Of levels,the
R10060 T13195 T13194 arg1Of levels,detectable
R10061 T13195 T13196 arg1Of levels,of
R10062 T13195 T13199 arg1Of levels,using
R10063 T13198 T13196 arg2Of phosphorylation,of
R10064 T13198 T13197 arg1Of phosphorylation,CREB
R10065 T13202 T13199 arg2Of antibody,using
R10066 T13202 T13200 arg1Of antibody,a
R10067 T13202 T13201 arg1Of antibody,phosphospecific
R10068 T13202 T13203 arg1Of antibody,for
R10069 T13204 T13203 arg2Of CREB-1,for
R10070 T13204 T13205 arg1Of CREB-1,(
R10071 T13207 T13205 arg2Of data,(
R10072 T13207 T13206 arg1Of data,unpublished
R10073 T13208 T13205 arg3Of ),(
R10074 T13212 T13213 arg1Of we,attempted
R10075 T13212 T13215 arg1Of we,determine
R10076 T13213 T13211 arg2Of attempted,when
R10077 T13215 T13213 arg2Of determine,attempted
R10078 T13215 T13214 arg1Of determine,to
R10079 T13217 T13218 arg1Of Foxp3,could
R10080 T13217 T13220 arg1Of Foxp3,interact
R10081 T13220 T13215 arg2Of interact,determine
R10082 T13220 T13216 arg1Of interact,whether
R10083 T13220 T13218 arg2Of interact,could
R10084 T13220 T13219 arg1Of interact,physically
R10085 T13220 T13221 arg1Of interact,with
R10086 T13225 T13221 arg2Of p300,with
R10087 T13225 T13222 arg1Of p300,the
R10088 T13225 T13223 arg1Of p300,coactivator
R10089 T13225 T13224 arg1Of p300,protein
R10090 T13227 T13228 arg1Of we,found
R10091 T13228 T13209 arg1Of found,However
R10092 T13228 T13210 arg1Of found,","
R10093 T13228 T13211 arg1Of found,when
R10094 T13228 T13226 arg1Of found,","
R10095 T13230 T13231 arg1Of p300,immunoprecipitated
R10096 T13231 T13228 arg2Of immunoprecipitated,found
R10097 T13231 T13229 arg1Of immunoprecipitated,that
R10098 T13231 T13233 arg1Of immunoprecipitated,when
R10099 T13232 T13231 arg2Of Foxp3,immunoprecipitated
R10100 T13235 T13234 arg1Of proteins,both
R10101 T13235 T13236 arg1Of proteins,were
R10102 T13235 T13237 arg2Of proteins,overexpressed
R10103 T13237 T13233 arg2Of overexpressed,when
R10104 T13237 T13236 arg2Of overexpressed,were
R10105 T13237 T13238 arg1Of overexpressed,in
R10106 T13241 T13238 arg2Of cells,in
R10107 T13241 T13239 arg1Of cells,HEK
R10108 T13241 T13240 arg1Of cells,293T
R10109 T13241 T13242 arg1Of cells,(
R10110 T13244 T13242 arg2Of 7D,(
R10111 T13244 T13243 arg1Of 7D,Figure
R10112 T13245 T13242 arg3Of ),(
R10113 T13249 T13248 arg1Of results,these
R10114 T13249 T13250 arg1Of results,suggest
R10115 T13250 T13246 arg1Of suggest,Collectively
R10116 T13250 T13247 arg1Of suggest,","
R10117 T13252 T13253 arg1Of Foxp3,antagonizes
R10118 T13253 T13250 arg2Of antagonizes,suggest
R10119 T13253 T13251 arg1Of antagonizes,that
R10120 T13253 T13257 arg1Of antagonizes,by
R10121 T13256 T13253 arg2Of expression,antagonizes
R10122 T13256 T13254 arg1Of expression,CREB-dependent
R10123 T13256 T13255 arg1Of expression,gene
R10124 T13259 T13260 arg1Of interacting,with
R10125 T13259 T13263 arg1Of interacting,and
R10126 T13262 T13260 arg2Of p300,with
R10127 T13262 T13261 arg1Of p300,coactivator
R10128 T13263 T13257 arg2Of and,by
R10129 T13263 T13258 arg1Of and,directly
R10130 T13264 T13263 arg2Of interfering,and
R10131 T13264 T13265 arg1Of interfering,with
R10132 T13267 T13268 arg1Of function,and/or
R10133 T13268 T13265 arg2Of and/or,with
R10134 T13268 T13266 arg1Of and/or,its
R10135 T13268 T13270 arg1Of and/or,to
R10136 T13269 T13268 arg2Of recruitment,and/or
R10137 T13273 T13270 arg2Of sequences,to
R10138 T13273 T13271 arg1Of sequences,CREB-responsive
R10139 T13273 T13272 arg1Of sequences,promoter
R12137 T15979 T15976 arg2Of study,In
R12138 T15979 T15977 arg1Of study,the
R12139 T15979 T15978 arg1Of study,present
R12140 T15981 T15982 arg1Of we,show
R12141 T15982 T15976 arg1Of show,In
R12142 T15982 T15980 arg1Of show,","
R12143 T15984 T15985 arg1Of Foxp3,functions
R12144 T15985 T15982 arg2Of functions,show
R12145 T15985 T15983 arg1Of functions,that
R12146 T15985 T15986 arg1Of functions,as
R12147 T15989 T15986 arg2Of repressor,as
R12148 T15989 T15987 arg1Of repressor,a
R12149 T15989 T15988 arg1Of repressor,potent
R12150 T15989 T15990 arg1Of repressor,of
R12151 T15991 T15992 arg1Of NF-κB-,and
R12152 T15992 T15990 arg2Of and,of
R12153 T15995 T15992 arg2Of activation,and
R12154 T15995 T15993 arg1Of activation,CREB-dependent
R12155 T15995 T15994 arg1Of activation,transcriptional
R12156 T16001 T15998 arg1Of domain,the
R12157 T16001 T15999 arg1Of domain,carboxyl-terminal
R12158 T16001 T16000 arg1Of domain,FKH
R12159 T16001 T16002 arg1Of domain,appears
R12160 T16001 T16004 arg1Of domain,be
R12161 T16001 T16005 arg1Of domain,dispensable
R12162 T16002 T15996 arg1Of appears,Furthermore
R12163 T16002 T15997 arg1Of appears,","
R12164 T16004 T16002 arg2Of be,appears
R12165 T16004 T16003 arg1Of be,to
R12166 T16005 T16004 arg2Of dispensable,be
R12167 T16005 T16006 arg1Of dispensable,for
R12168 T16007 T16006 arg2Of mediating,for
R12169 T16007 T16010 arg1Of mediating,","
R12170 T16007 T16013 arg1Of mediating,in
R12171 T16009 T16007 arg2Of effects,mediating
R12172 T16009 T16008 arg1Of effects,these
R12173 T16012 T16011 arg1Of least,at
R12174 T16013 T16012 arg1Of in,least
R12175 T16016 T16013 arg2Of populations,in
R12176 T16016 T16014 arg1Of populations,T
R12177 T16016 T16015 arg1Of populations,cell
R12178 T16018 T16017 arg1Of observation,This
R12179 T16018 T16019 arg1Of observation,may
R12180 T16018 T16020 arg1Of observation,become
R12181 T16018 T16021 arg1Of observation,important
R12182 T16020 T16019 arg2Of become,may
R12183 T16020 T16022 arg1Of become,in
R12184 T16021 T16020 arg2Of important,become
R12185 T16023 T16022 arg2Of light,in
R12186 T16023 T16024 arg1Of light,of
R12187 T16026 T16024 arg2Of reports,of
R12188 T16026 T16025 arg1Of reports,recent
R12189 T16026 T16027 arg1Of reports,suggesting
R12190 T16030 T16029 arg1Of expression,Foxp3
R12191 T16030 T16031 arg1Of expression,in
R12192 T16030 T16035 arg1Of expression,was
R12193 T16030 T16036 arg1Of expression,crucial
R12194 T16030 T16038 arg1Of expression,directing
R12195 T16034 T16031 arg2Of cells,in
R12196 T16034 T16032 arg1Of cells,thymic
R12197 T16034 T16033 arg1Of cells,epithelial
R12198 T16035 T16027 arg2Of was,suggesting
R12199 T16035 T16028 arg1Of was,that
R12200 T16036 T16035 arg2Of crucial,was
R12201 T16036 T16037 arg1Of crucial,for
R12202 T16038 T16037 arg2Of directing,for
R12203 T16038 T16046 arg1Of directing,[
R12204 T16039 T16038 arg2Of development,directing
R12205 T16039 T16040 arg1Of development,of
R12206 T16039 T16043 arg1Of development,in
R12207 T16042 T16040 arg2Of cells,of
R12208 T16042 T16041 arg1Of cells,T
R12209 T16045 T16043 arg2Of thymus,in
R12210 T16045 T16044 arg1Of thymus,the
R12211 T16047 T16046 arg2Of 42,[
R12212 T16048 T16046 arg3Of ],[
R12213 T16052 T16051 arg1Of majority,the
R12214 T16052 T16053 arg1Of majority,of
R12215 T16052 T16072 arg1Of majority,map
R12216 T16056 T16053 arg2Of mutations,of
R12217 T16056 T16054 arg1Of mutations,the
R12218 T16056 T16055 arg1Of mutations,genetic
R12219 T16056 T16057 arg2Of mutations,associated
R12220 T16057 T16058 arg1Of associated,with
R12221 T16059 T16058 arg2Of IPEX,with
R12222 T16059 T16060 arg1Of IPEX,","
R12223 T16064 T16060 arg2Of disorder,","
R12224 T16064 T16061 arg1Of disorder,a
R12225 T16064 T16062 arg1Of disorder,severe
R12226 T16064 T16063 arg1Of disorder,autoimmune
R12227 T16064 T16065 arg2Of disorder,caused
R12228 T16068 T16065 arg1Of inactivation,caused
R12229 T16068 T16066 arg2Of inactivation,by
R12230 T16068 T16067 arg1Of inactivation,functional
R12231 T16068 T16069 arg1Of inactivation,of
R12232 T16070 T16069 arg2Of Foxp3,of
R12233 T16072 T16049 arg1Of map,Interestingly
R12234 T16072 T16050 arg1Of map,","
R12235 T16072 T16071 arg1Of map,","
R12236 T16072 T16073 arg1Of map,to
R12237 T16072 T16083 arg1Of map,in
R12238 T16077 T16074 arg1Of domain,the
R12239 T16077 T16075 arg1Of domain,carboxyl-terminal
R12240 T16077 T16076 arg1Of domain,FKH
R12241 T16077 T16078 arg1Of domain,or
R12242 T16078 T16073 arg2Of or,to
R12243 T16082 T16078 arg2Of domain,or
R12244 T16082 T16079 arg1Of domain,the
R12245 T16082 T16080 arg1Of domain,leucine
R12246 T16082 T16081 arg1Of domain,zipper
R12247 T16086 T16083 arg2Of region,in
R12248 T16086 T16084 arg1Of region,the
R12249 T16086 T16085 arg1Of region,central
R12250 T16086 T16087 arg1Of region,of
R12251 T16089 T16087 arg2Of protein,of
R12252 T16089 T16088 arg1Of protein,the
R12253 T16091 T16090 arg1Of one,Only
R12254 T16092 T16091 arg1Of mutation,one
R12255 T16092 T16093 arg2Of mutation,associated
R12256 T16092 T16098 arg1Of mutation,has
R12257 T16092 T16099 arg1Of mutation,been
R12258 T16092 T16100 arg2Of mutation,mapped
R12259 T16093 T16094 arg1Of associated,with
R12260 T16095 T16094 arg2Of IPEX,with
R12261 T16095 T16096 arg1Of IPEX,to
R12262 T16097 T16096 arg2Of date,to
R12263 T16100 T16098 arg2Of mapped,has
R12264 T16100 T16099 arg2Of mapped,been
R12265 T16100 T16101 arg1Of mapped,to
R12266 T16105 T16101 arg2Of region,to
R12267 T16105 T16102 arg1Of region,the
R12268 T16105 T16103 arg1Of region,amino-terminal
R12269 T16105 T16104 arg1Of region,proline-rich
R12270 T16105 T16106 arg1Of region,[
R12271 T16107 T16106 arg2Of 43,[
R12272 T16108 T16106 arg3Of ],[
R12273 T16110 T16148 arg1Of is,whereas
R12274 T16111 T16110 arg2Of possible,is
R12275 T16115 T16113 arg1Of domain,the
R12276 T16115 T16114 arg1Of domain,FKH
R12277 T16115 T16116 arg1Of domain,has
R12278 T16116 T16112 arg1Of has,that
R12279 T16116 T16131 arg1Of has,and
R12280 T16120 T16116 arg2Of structure,has
R12281 T16120 T16117 arg1Of structure,a
R12282 T16120 T16118 arg1Of structure,complex
R12283 T16120 T16119 arg1Of structure,tertiary
R12284 T16120 T16121 arg1Of structure,that
R12285 T16120 T16122 arg1Of structure,is
R12286 T16120 T16124 arg1Of structure,sensitive
R12287 T16124 T16122 arg2Of sensitive,is
R12288 T16124 T16123 arg1Of sensitive,particularly
R12289 T16124 T16125 arg1Of sensitive,to
R12290 T16126 T16125 arg2Of misfolding,to
R12291 T16126 T16127 arg2Of misfolding,caused
R12292 T16130 T16127 arg1Of mutations,caused
R12293 T16130 T16128 arg2Of mutations,by
R12294 T16130 T16129 arg1Of mutations,genetic
R12295 T16131 T16109 arg1Of and,It
R12296 T16131 T16110 arg1Of and,is
R12297 T16131 T16111 arg1Of and,possible
R12298 T16132 T16131 arg2Of that,and
R12299 T16136 T16133 arg1Of domain,an
R12300 T16136 T16134 arg1Of domain,intact
R12301 T16136 T16135 arg1Of domain,FKH
R12302 T16136 T16137 arg1Of domain,is
R12303 T16136 T16139 arg1Of domain,critical
R12304 T16137 T16132 arg2Of is,that
R12305 T16139 T16137 arg2Of critical,is
R12306 T16139 T16138 arg1Of critical,absolutely
R12307 T16139 T16140 arg1Of critical,for
R12308 T16141 T16140 arg2Of promoting,for
R12309 T16141 T16144 arg1Of promoting,in
R12310 T16143 T16141 arg2Of function,promoting
R12311 T16143 T16142 arg1Of function,Foxp3
R12312 T16146 T16144 arg2Of nucleus,in
R12313 T16146 T16145 arg1Of nucleus,the
R12314 T16148 T16147 arg1Of whereas,","
R12315 T16150 T16149 arg1Of structure,the
R12316 T16150 T16151 arg1Of structure,of
R12317 T16150 T16156 arg1Of structure,may
R12318 T16150 T16157 arg1Of structure,tolerate
R12319 T16155 T16151 arg2Of region,of
R12320 T16155 T16152 arg1Of region,the
R12321 T16155 T16153 arg1Of region,amino-terminal
R12322 T16155 T16154 arg1Of region,proline-rich
R12323 T16157 T16148 arg2Of tolerate,whereas
R12324 T16157 T16156 arg2Of tolerate,may
R12325 T16157 T16161 arg1Of tolerate,long
R12326 T16159 T16157 arg2Of mutations,tolerate
R12327 T16159 T16158 arg1Of mutations,certain
R12328 T16161 T16160 arg1Of long,as
R12329 T16162 T16161 arg2Of as,long
R12330 T16166 T16163 arg1Of motif,the
R12331 T16166 T16164 arg1Of motif,NF-κB/NF-AT
R12332 T16166 T16165 arg1Of motif,binding
R12333 T16166 T16167 arg1Of motif,remains
R12334 T16166 T16168 arg1Of motif,unaltered
R12335 T16167 T16162 arg2Of remains,as
R12336 T16168 T16167 arg2Of unaltered,remains
R12337 T16170 T16169 arg1Of motif,This
R12338 T16170 T16171 arg1Of motif,may
R12339 T16170 T16173 arg1Of motif,include
R12340 T16173 T16171 arg2Of include,may
R12341 T16173 T16172 arg1Of include,also
R12342 T16177 T16173 arg2Of domain,include
R12343 T16177 T16174 arg1Of domain,the
R12344 T16177 T16175 arg1Of domain,zinc
R12345 T16177 T16176 arg1Of domain,finger
R12346 T16180 T16178 arg1Of region,A
R12347 T16180 T16179 arg1Of region,logical
R12348 T16180 T16181 arg1Of region,that
R12349 T16180 T16182 arg1Of region,may
R12350 T16180 T16183 arg1Of region,be
R12351 T16180 T16184 arg2Of region,targeted
R12352 T16180 T16192 arg1Of region,is
R12353 T16184 T16182 arg2Of targeted,may
R12354 T16184 T16183 arg2Of targeted,be
R12355 T16189 T16184 arg1Of region,targeted
R12356 T16189 T16185 arg2Of region,by
R12357 T16189 T16186 arg1Of region,the
R12358 T16189 T16187 arg1Of region,amino-terminal
R12359 T16189 T16188 arg1Of region,proline-rich
R12360 T16189 T16190 arg1Of region,of
R12361 T16191 T16190 arg2Of Foxp3,of
R12362 T16196 T16192 arg2Of domain,is
R12363 T16196 T16193 arg1Of domain,the
R12364 T16196 T16194 arg1Of domain,Rel
R12365 T16196 T16195 arg1Of domain,homology
R12366 T16196 T16197 arg2Of domain,found
R12367 T16197 T16198 arg1Of found,in
R12368 T16200 T16201 arg1Of NF-κB,and
R12369 T16202 T16201 arg2Of NF-AT,and
R12370 T16204 T16198 arg2Of proteins,in
R12371 T16204 T16199 arg1Of proteins,both
R12372 T16204 T16200 arg1Of proteins,NF-κB
R12373 T16204 T16202 arg1Of proteins,NF-AT
R12374 T16204 T16203 arg1Of proteins,family
R12375 T16206 T16205 arg1Of region,A
R12376 T16206 T16207 arg1Of region,that
R12377 T16206 T16208 arg1Of region,may
R12378 T16206 T16210 arg1Of region,be
R12379 T16206 T16211 arg1Of region,important
R12380 T16206 T16217 arg1Of region,is
R12381 T16210 T16208 arg2Of be,may
R12382 T16210 T16209 arg1Of be,also
R12383 T16211 T16210 arg2Of important,be
R12384 T16211 T16212 arg1Of important,with
R12385 T16211 T16214 arg1Of important,to
R12386 T16213 T16212 arg2Of respect,with
R12387 T16216 T16214 arg2Of function,to
R12388 T16216 T16215 arg1Of function,Foxp3
R12389 T16217 T16222 arg1Of is,","
R12390 T16217 T16223 arg1Of is,as
R12391 T16221 T16217 arg2Of domain,is
R12392 T16221 T16218 arg1Of domain,the
R12393 T16221 T16219 arg1Of domain,leucine
R12394 T16221 T16220 arg1Of domain,zipper
R12395 T16224 T16223 arg2Of demonstrated,as
R12396 T16227 T16224 arg1Of number,demonstrated
R12397 T16227 T16225 arg2Of number,by
R12398 T16227 T16226 arg1Of number,the
R12399 T16227 T16228 arg1Of number,of
R12400 T16229 T16228 arg2Of mutations,of
R12401 T16229 T16230 arg2Of mutations,associated
R12402 T16230 T16231 arg1Of associated,with
R12403 T16232 T16231 arg2Of IPEX,with
R12404 T16232 T16233 arg1Of IPEX,that
R12405 T16232 T16234 arg1Of IPEX,have
R12406 T16232 T16235 arg1Of IPEX,been
R12407 T16232 T16236 arg2Of IPEX,mapped
R12408 T16236 T16234 arg2Of mapped,have
R12409 T16236 T16235 arg2Of mapped,been
R12410 T16236 T16237 arg1Of mapped,in
R12411 T16239 T16237 arg2Of region,in
R12412 T16239 T16238 arg1Of region,this
R12413 T16239 T16240 arg1Of region,of
R12414 T16241 T16240 arg2Of Foxp3,of
R12415 T16243 T16242 arg1Of role,The
R12416 T16243 T16244 arg1Of role,of
R12417 T16243 T16247 arg1Of role,in
R12418 T16243 T16250 arg1Of role,remains
R12419 T16243 T16251 arg1Of role,uncharacterized
R12420 T16243 T16254 arg1Of role,may
R12421 T16243 T16255 arg1Of role,play
R12422 T16246 T16244 arg2Of domain,of
R12423 T16246 T16245 arg1Of domain,this
R12424 T16249 T16247 arg2Of function,in
R12425 T16249 T16248 arg1Of function,Foxp3
R12426 T16250 T16253 arg1Of remains,but
R12427 T16251 T16250 arg2Of uncharacterized,remains
R12428 T16253 T16252 arg1Of but,","
R12429 T16255 T16253 arg2Of play,but
R12430 T16255 T16254 arg2Of play,may
R12431 T16255 T16258 arg1Of play,in
R12432 T16255 T16261 arg1Of play,as
R12433 T16257 T16255 arg2Of role,play
R12434 T16257 T16256 arg1Of role,a
R12435 T16260 T16258 arg2Of formation,in
R12436 T16260 T16259 arg1Of formation,dimer
R12437 T16262 T16263 arg1Of it,does
R12438 T16263 T16261 arg2Of does,as
R12439 T16263 T16264 arg1Of does,in
R12440 T16263 T16269 arg1Of does,[
R12441 T16268 T16264 arg2Of members,in
R12442 T16268 T16265 arg1Of members,other
R12443 T16268 T16266 arg1Of members,Foxp
R12444 T16268 T16267 arg1Of members,family
R12445 T16270 T16269 arg2Of 44,[
R12446 T16271 T16269 arg3Of ],[
R12447 T16274 T16273 arg1Of pathogenesis,the
R12448 T16274 T16275 arg1Of pathogenesis,of
R12449 T16274 T16287 arg1Of pathogenesis,have
R12450 T16274 T16288 arg1Of pathogenesis,been
R12451 T16274 T16289 arg2Of pathogenesis,associated
R12452 T16277 T16275 arg2Of number,of
R12453 T16277 T16276 arg1Of number,a
R12454 T16277 T16278 arg1Of number,of
R12455 T16281 T16278 arg2Of disorders,of
R12456 T16281 T16279 arg1Of disorders,retroviral-induced
R12457 T16281 T16280 arg1Of disorders,immunologic
R12458 T16281 T16283 arg1Of disorders,as
R12459 T16283 T16282 arg1Of as,such
R12460 T16284 T16285 arg1Of HIV-1/AIDS,and
R12461 T16285 T16283 arg2Of and,as
R12462 T16286 T16285 arg2Of HTLV-I/HAM/TSP,and
R12463 T16289 T16272 arg2Of associated,Because
R12464 T16289 T16287 arg2Of associated,have
R12465 T16289 T16288 arg2Of associated,been
R12466 T16289 T16290 arg1Of associated,with
R12467 T16291 T16290 arg2Of dysregulation,with
R12468 T16291 T16292 arg1Of dysregulation,of
R12469 T16294 T16292 arg2Of expression,of
R12470 T16294 T16293 arg1Of expression,Foxp3
R12471 T16294 T16295 arg1Of expression,[
R12472 T16296 T16295 arg2Of "8,45",[
R12473 T16297 T16295 arg3Of ],[
R12474 T16299 T16301 arg1Of we,examined
R12475 T16301 T16272 arg1Of examined,Because
R12476 T16301 T16298 arg1Of examined,","
R12477 T16301 T16300 arg1Of examined,also
R12478 T16303 T16301 arg2Of role,examined
R12479 T16303 T16302 arg1Of role,the
R12480 T16303 T16304 arg1Of role,of
R12481 T16303 T16306 arg1Of role,in
R12482 T16305 T16304 arg2Of Foxp3,of
R12483 T16309 T16306 arg2Of expression,in
R12484 T16309 T16307 arg1Of expression,retroviral
R12485 T16309 T16308 arg1Of expression,gene
R12486 T16312 T16310 arg1Of activation,HIV-1
R12487 T16312 T16311 arg1Of activation,LTR
R12488 T16312 T16313 arg1Of activation,in
R12489 T16312 T16317 arg1Of activation,is
R12490 T16312 T16319 arg1Of activation,dependent
R12491 T16316 T16313 arg2Of cells,in
R12492 T16316 T16314 arg1Of cells,CD4+
R12493 T16316 T16315 arg1Of cells,T
R12494 T16317 T16338 arg1Of is,whereas
R12495 T16319 T16317 arg2Of dependent,is
R12496 T16319 T16318 arg1Of dependent,critically
R12497 T16319 T16320 arg1Of dependent,on
R12498 T16324 T16320 arg2Of sites,on
R12499 T16324 T16321 arg1Of sites,two
R12500 T16324 T16322 arg1Of sites,tandem
R12501 T16324 T16323 arg1Of sites,NF-κB
R12502 T16324 T16325 arg1Of sites,located
R12503 T16325 T16326 arg1Of located,between
R12504 T16329 T16330 arg1Of −102,and
R12505 T16330 T16326 arg2Of and,between
R12506 T16330 T16327 arg1Of and,nucleotide
R12507 T16330 T16328 arg1Of and,positions
R12508 T16330 T16332 arg1Of and,within
R12509 T16331 T16330 arg2Of −81,and
R12510 T16336 T16332 arg2Of region,within
R12511 T16336 T16333 arg1Of region,the
R12512 T16336 T16334 arg1Of region,HIV-1
R12513 T16336 T16335 arg1Of region,enhancer
R12514 T16338 T16337 arg1Of whereas,","
R12515 T16338 T16357 arg1Of whereas,[
R12516 T16341 T16339 arg1Of activation,HTLV-I
R12517 T16341 T16340 arg1Of activation,LTR
R12518 T16341 T16342 arg1Of activation,in
R12519 T16341 T16353 arg1Of activation,is
R12520 T16341 T16354 arg1Of activation,independent
R12521 T16344 T16345 arg1Of presence,or
R12522 T16345 T16342 arg2Of or,in
R12523 T16345 T16343 arg1Of or,the
R12524 T16345 T16347 arg1Of or,of
R12525 T16346 T16345 arg2Of absence,or
R12526 T16352 T16347 arg2Of Tax,of
R12527 T16352 T16348 arg1Of Tax,the
R12528 T16352 T16349 arg1Of Tax,HTLV-I-encoded
R12529 T16352 T16350 arg1Of Tax,transactivator
R12530 T16352 T16351 arg1Of Tax,protein
R12531 T16353 T16338 arg2Of is,whereas
R12532 T16354 T16353 arg2Of independent,is
R12533 T16354 T16355 arg1Of independent,of
R12534 T16356 T16355 arg2Of NF-κB,of
R12535 T16358 T16357 arg2Of 18,[
R12536 T16359 T16357 arg3Of ],[
R12537 T16362 T16360 arg2Of knowledge,To
R12538 T16362 T16361 arg1Of knowledge,our
R12539 T16362 T16363 arg1Of knowledge,for
R12540 T16366 T16363 arg2Of time,for
R12541 T16366 T16364 arg1Of time,the
R12542 T16366 T16365 arg1Of time,first
R12543 T16368 T16369 arg1Of Foxp3,was
R12544 T16368 T16370 arg2Of Foxp3,shown
R12545 T16368 T16372 arg1Of Foxp3,have
R12546 T16370 T16360 arg1Of shown,To
R12547 T16370 T16367 arg1Of shown,","
R12548 T16370 T16369 arg2Of shown,was
R12549 T16372 T16370 arg3Of have,shown
R12550 T16372 T16371 arg1Of have,to
R12551 T16372 T16376 arg1Of have,on
R12552 T16375 T16372 arg2Of effect,have
R12553 T16375 T16373 arg1Of effect,a
R12554 T16375 T16374 arg1Of effect,direct
R12555 T16379 T16376 arg2Of transcription,on
R12556 T16379 T16377 arg1Of transcription,HIV-1
R12557 T16379 T16378 arg1Of transcription,LTR
R12558 T16380 T16381 arg1Of Deletion,of
R12559 T16380 T16390 arg1Of Deletion,reduced
R12560 T16384 T16381 arg2Of sites,of
R12561 T16384 T16382 arg1Of sites,the
R12562 T16384 T16383 arg1Of sites,NF-κB
R12563 T16384 T16385 arg1Of sites,within
R12564 T16389 T16385 arg2Of region,within
R12565 T16389 T16386 arg1Of region,the
R12566 T16389 T16387 arg1Of region,HIV-1
R12567 T16389 T16388 arg1Of region,enhancer
R12568 T16392 T16390 arg2Of responsiveness,reduced
R12569 T16392 T16391 arg1Of responsiveness,the
R12570 T16392 T16393 arg1Of responsiveness,of
R12571 T16392 T16397 arg1Of responsiveness,to
R12572 T16396 T16393 arg2Of LTR,of
R12573 T16396 T16394 arg1Of LTR,the
R12574 T16396 T16395 arg1Of LTR,HIV-1
R12575 T16399 T16397 arg2Of suppression,to
R12576 T16399 T16398 arg1Of suppression,Foxp3-mediated
R12577 T16401 T16400 arg2Of addition,In
R12578 T16405 T16403 arg1Of domain,the
R12579 T16405 T16404 arg1Of domain,FKH
R12580 T16405 T16406 arg1Of domain,of
R12581 T16405 T16408 arg1Of domain,was
R12582 T16405 T16409 arg2Of domain,required
R12583 T16407 T16406 arg2Of Foxp3,of
R12584 T16409 T16400 arg1Of required,In
R12585 T16409 T16402 arg1Of required,","
R12586 T16409 T16408 arg2Of required,was
R12587 T16409 T16410 arg1Of required,for
R12588 T16409 T16421 arg1Of required,in
R12589 T16410 T16419 arg1Of for,but
R12590 T16413 T16410 arg2Of effect,for
R12591 T16413 T16411 arg1Of effect,this
R12592 T16413 T16412 arg1Of effect,inhibitory
R12593 T16413 T16414 arg1Of effect,in
R12594 T16417 T16414 arg2Of cells,in
R12595 T16417 T16415 arg1Of cells,HEK
R12596 T16417 T16416 arg1Of cells,293T
R12597 T16419 T16418 arg1Of but,","
R12598 T16421 T16419 arg2Of in,but
R12599 T16421 T16420 arg1Of in,not
R12600 T16424 T16421 arg2Of cells,in
R12601 T16424 T16422 arg1Of cells,Jurkat
R12602 T16424 T16423 arg1Of cells,T
R12603 T16424 T16425 arg1Of cells,","
R12604 T16424 T16426 arg1Of cells,similar
R12605 T16426 T16427 arg1Of similar,to
R12606 T16429 T16427 arg2Of suppression,to
R12607 T16429 T16428 arg1Of suppression,Foxp3-mediated
R12608 T16429 T16430 arg1Of suppression,of
R12609 T16434 T16430 arg2Of reporter,of
R12610 T16434 T16431 arg1Of reporter,a
R12611 T16434 T16432 arg1Of reporter,synthetic
R12612 T16434 T16433 arg1Of reporter,NF-κB
R12613 T16437 T16435 arg1Of effect,The
R12614 T16437 T16436 arg1Of effect,direct
R12615 T16437 T16438 arg1Of effect,of
R12616 T16437 T16444 arg1Of effect,correlates
R12617 T16443 T16438 arg2Of expression,of
R12618 T16443 T16439 arg1Of expression,Foxp3
R12619 T16443 T16440 arg1Of expression,down-regulating
R12620 T16443 T16441 arg1Of expression,HIV-1
R12621 T16443 T16442 arg1Of expression,gene
R12622 T16444 T16445 arg1Of correlates,well
R12623 T16444 T16446 arg1Of correlates,with
R12624 T16448 T16447 arg1Of reported,recently
R12625 T16449 T16446 arg2Of evidence,with
R12626 T16449 T16448 arg1Of evidence,reported
R12627 T16449 T16450 arg1Of evidence,indicating
R12628 T16453 T16452 arg1Of regulatory,higher
R12629 T16454 T16453 arg1Of activity,regulatory
R12630 T16454 T16455 arg1Of activity,of
R12631 T16454 T16462 arg1Of activity,was
R12632 T16454 T16463 arg2Of activity,associated
R12633 T16458 T16455 arg2Of cells,of
R12634 T16458 T16456 arg1Of cells,CD4+CD25+
R12635 T16458 T16457 arg1Of cells,T
R12636 T16458 T16459 arg1Of cells,from
R12637 T16461 T16459 arg2Of patients,from
R12638 T16461 T16460 arg1Of patients,HIV-1-infected
R12639 T16463 T16450 arg2Of associated,indicating
R12640 T16463 T16451 arg1Of associated,that
R12641 T16463 T16462 arg2Of associated,was
R12642 T16463 T16464 arg1Of associated,with
R12643 T16463 T16472 arg1Of associated,[
R12644 T16468 T16464 arg2Of loads,with
R12645 T16468 T16465 arg1Of loads,lower
R12646 T16468 T16466 arg1Of loads,HIV-1
R12647 T16468 T16467 arg1Of loads,viral
R12648 T16468 T16469 arg1Of loads,in
R12649 T16471 T16469 arg2Of patients,in
R12650 T16471 T16470 arg1Of patients,these
R12651 T16473 T16472 arg2Of 46,[
R12652 T16474 T16472 arg3Of ],[
R12653 T16475 T16477 arg1Of Foxp3,affected
R12654 T16477 T16476 arg1Of affected,also
R12655 T16477 T16484 arg1Of affected,:
R12656 T16542 T16541 arg1Of series,This
R12657 T16542 T16543 arg1Of series,of
R12658 T16542 T16545 arg1Of series,allows
R12659 T16480 T16477 arg2Of functions,affected
R12660 T16544 T16543 arg2Of steps,of
R12661 T16480 T16478 arg1Of functions,two
R12662 T16546 T16545 arg2Of Tax,allows
R12663 T16546 T16548 arg1Of Tax,recruit
R12664 T16546 T16557 arg1Of Tax,facilitate
R12665 T16480 T16479 arg1Of functions,well-known
R12666 T16548 T16552 arg1Of recruit,to
R12667 T16548 T16556 arg1Of recruit,and
R12668 T16480 T16481 arg1Of functions,of
R12669 T16483 T16481 arg2Of Tax,of
R12670 T16551 T16548 arg2Of CBP/p300,recruit
R12671 T16551 T16549 arg1Of CBP/p300,coactivator
R12672 T16551 T16550 arg1Of CBP/p300,proteins
R12673 T16555 T16552 arg2Of promoter,to
R12674 T16555 T16553 arg1Of promoter,the
R12675 T16555 T16554 arg1Of promoter,viral
R12676 T16556 T16545 arg3Of and,allows
R12677 T16556 T16547 arg1Of and,to
R12678 T16483 T16482 arg1Of Tax,HTLV-I
R12679 T16557 T16556 arg2Of facilitate,and
R12680 T16557 T16565 arg1Of facilitate,[
R12681 T16485 T16486 arg1Of transactivation,of
R12682 T16560 T16557 arg2Of level,facilitate
R12683 T16560 T16558 arg1Of level,a
R12684 T16560 T16559 arg1Of level,high
R12685 T16560 T16561 arg1Of level,of
R12686 T16485 T16490 arg1Of transactivation,and
R12687 T16485 T16491 arg1Of transactivation,","
R12688 T16564 T16561 arg2Of expression,of
R12689 T16564 T16562 arg1Of expression,viral
R12690 T16564 T16563 arg1Of expression,gene
R12691 T16485 T16493 arg1Of transactivation,surprisingly
R12692 T16566 T16565 arg2Of 24–26,[
R12693 T16485 T16494 arg1Of transactivation,","
R12694 T16567 T16565 arg3Of ],[
R12695 T16568 T16569 arg1Of Transactivation,of
R12696 T16568 T16573 arg1Of Transactivation,by
R12697 T16568 T16575 arg1Of Transactivation,was
R12698 T16568 T16576 arg2Of Transactivation,inhibited
R12699 T16572 T16569 arg2Of pathway,of
R12700 T16572 T16570 arg1Of pathway,the
R12701 T16572 T16571 arg1Of pathway,NF-κB
R12702 T16489 T16486 arg2Of pathway,of
R12703 T16574 T16573 arg2Of Tax,by
R12704 T16576 T16575 arg2Of inhibited,was
R12705 T16576 T16586 arg1Of inhibited,","
R12706 T16576 T16587 arg1Of inhibited,as
R12707 T16578 T16579 arg1Of overexpression,of
R12708 T16578 T16583 arg1Of overexpression,but
R12709 T16489 T16487 arg1Of pathway,the
R12710 T16581 T16579 arg2Of Foxp3,of
R12711 T16581 T16580 arg1Of Foxp3,full-length
R12712 T16489 T16488 arg1Of pathway,NF-κB
R12713 T16583 T16576 arg1Of but,inhibited
R12714 T16583 T16577 arg2Of but,by
R12715 T16583 T16582 arg1Of but,","
R12716 T16583 T16584 arg1Of but,not
R12717 T16493 T16492 arg1Of surprisingly,most
R12718 T16585 T16583 arg2Of ΔFKH,but
R12719 T16588 T16587 arg2Of seen,as
R12720 T16588 T16589 arg1Of seen,with
R12721 T16591 T16590 arg1Of activation,basal
R12722 T16591 T16592 arg1Of activation,of
R12723 T16591 T16596 arg1Of activation,and
R12724 T16494 T16477 arg3Of ",",affected
R12725 T16495 T16494 arg2Of transactivation,","
R12726 T16595 T16592 arg2Of LTR,of
R12727 T16595 T16593 arg1Of LTR,the
R12728 T16595 T16594 arg1Of LTR,HIV-1
R12729 T16596 T16589 arg2Of and,with
R12730 T16495 T16496 arg1Of transactivation,of
R12731 T16499 T16496 arg2Of LTR,of
R12732 T16600 T16596 arg2Of reporter,and
R12733 T16600 T16597 arg1Of reporter,a
R12734 T16600 T16598 arg1Of reporter,synthetic
R12735 T16600 T16599 arg1Of reporter,NF-κB
R12736 T16600 T16601 arg1Of reporter,in
R12737 T16604 T16601 arg2Of cells,in
R12738 T16604 T16602 arg1Of cells,HEK
R12739 T16604 T16603 arg1Of cells,293T
R12740 T16499 T16497 arg1Of LTR,the
R12741 T16499 T16498 arg1Of LTR,HTLV-I
R12742 T16500 T16501 arg1Of Transactivation,of
R12743 T16608 T16607 arg1Of transactivation,Tax-mediated
R12744 T16608 T16609 arg1Of transactivation,of
R12745 T16608 T16613 arg1Of transactivation,was
R12746 T16608 T16614 arg2Of transactivation,inhibited
R12747 T16612 T16609 arg2Of LTR,of
R12748 T16612 T16610 arg1Of LTR,the
R12749 T16612 T16611 arg1Of LTR,HTLV-I
R12750 T16500 T16505 arg1Of Transactivation,by
R12751 T16614 T16605 arg1Of inhibited,However
R12752 T16614 T16606 arg1Of inhibited,","
R12753 T16500 T16507 arg1Of Transactivation,involves
R12754 T16504 T16501 arg2Of LTR,of
R12755 T16614 T16613 arg2Of inhibited,was
R12756 T16614 T16625 arg1Of inhibited,in
R12757 T16616 T16614 arg1Of overexpression,inhibited
R12758 T16616 T16615 arg2Of overexpression,by
R12759 T16616 T16617 arg1Of overexpression,of
R12760 T16504 T16502 arg1Of LTR,the
R12761 T16620 T16619 arg1Of Foxp3,full-length
R12762 T16620 T16623 arg1Of Foxp3,as
R12763 T16504 T16503 arg1Of LTR,HTLV-I
R12764 T16506 T16505 arg2Of Tax,by
R12765 T16623 T16617 arg2Of as,of
R12766 T16623 T16618 arg1Of as,both
R12767 T16623 T16621 arg1Of as,as
R12768 T16623 T16622 arg1Of as,well
R12769 T16624 T16623 arg2Of ΔFKH,as
R12770 T16509 T16507 arg2Of interaction,involves
R12771 T16629 T16627 arg1Of cells,HEK
R12772 T16629 T16628 arg1Of cells,293T
R12773 T16629 T16630 arg1Of cells,and
R12774 T16630 T16625 arg2Of and,in
R12775 T16630 T16626 arg1Of and,both
R12776 T16633 T16630 arg2Of cells,and
R12777 T16633 T16631 arg1Of cells,CD4+
R12778 T16633 T16632 arg1Of cells,T
R12779 T16509 T16508 arg1Of interaction,the
R12780 T16634 T16635 arg1Of We,demonstrated
R12781 T16509 T16510 arg1Of interaction,of
R12782 T16509 T16513 arg1Of interaction,with
R12783 T16509 T16515 arg1Of interaction,in
R12784 T16637 T16638 arg1Of Foxp3,did
R12785 T16637 T16641 arg1Of Foxp3,affect
R12786 T16512 T16510 arg2Of factors,of
R12787 T16512 T16511 arg1Of factors,ATF/CREB
R12788 T16514 T16513 arg2Of Tax,with
R12789 T16517 T16515 arg2Of nucleus,in
R12790 T16641 T16638 arg2Of affect,did
R12791 T16641 T16639 arg1Of affect,not
R12792 T16641 T16640 arg1Of affect,directly
R12793 T16641 T16647 arg1Of affect,but
R12794 T16643 T16641 arg2Of functioning,affect
R12795 T16643 T16642 arg1Of functioning,the
R12796 T16643 T16644 arg1Of functioning,of
R12797 T16645 T16644 arg2Of Tax,of
R12798 T16647 T16635 arg2Of but,demonstrated
R12799 T16647 T16636 arg1Of but,that
R12800 T16647 T16646 arg1Of but,","
R12801 T16517 T16516 arg1Of nucleus,the
R12802 T16649 T16648 arg1Of Foxp3,rather
R12803 T16649 T16650 arg1Of Foxp3,targeted
R12804 T16518 T16519 arg1Of Binding,of
R12805 T16650 T16647 arg2Of targeted,but
R12806 T16518 T16521 arg1Of Binding,enhances
R12807 T16653 T16650 arg2Of factors,targeted
R12808 T16653 T16651 arg1Of factors,the
R12809 T16653 T16652 arg1Of factors,transcription
R12810 T16653 T16654 arg2Of factors,required
R12811 T16653 T16658 arg1Of factors,(
R12812 T16654 T16655 arg1Of required,for
R12813 T16518 T16525 arg1Of Binding,promotes
R12814 T16520 T16519 arg2Of Tax,of
R12815 T16657 T16655 arg2Of transactivation,for
R12816 T16657 T16656 arg1Of transactivation,Tax
R12817 T16521 T16524 arg1Of enhances,and
R12818 T16661 T16659 arg1Of NF-κB,i.e.
R12819 T16661 T16660 arg1Of NF-κB,","
R12820 T16661 T16662 arg1Of NF-κB,and
R12821 T16662 T16658 arg2Of and,(
R12822 T16523 T16521 arg2Of dimerization,enhances
R12823 T16666 T16662 arg2Of factor,and
R12824 T16666 T16663 arg1Of factor,a
R12825 T16666 T16664 arg1Of factor,then-unknown
R12826 T16666 T16665 arg1Of factor,cellular
R12827 T16666 T16667 arg1Of factor,","
R12828 T16666 T16668 arg1Of factor,which
R12829 T16666 T16670 arg2Of factor,identified
R12830 T16523 T16522 arg1Of dimerization,ATF/CREB
R12831 T16669 T16670 arg1Of we,identified
R12832 T16525 T16524 arg2Of promotes,and
R12833 T16670 T16671 arg1Of identified,in
R12834 T16526 T16525 arg2Of assembly,promotes
R12835 T16673 T16671 arg2Of study,in
R12836 T16673 T16672 arg1Of study,this
R12837 T16673 T16674 arg1Of study,as
R12838 T16675 T16674 arg2Of CREB,as
R12839 T16526 T16527 arg1Of assembly,of
R12840 T16676 T16658 arg3Of ),(
R12841 T16526 T16530 arg1Of assembly,onto
R12842 T16526 T16533 arg1Of assembly,in
R12843 T16679 T16677 arg1Of effect,The
R12844 T16529 T16527 arg2Of complexes,of
R12845 T16679 T16678 arg1Of effect,negative
R12846 T16679 T16680 arg1Of effect,of
R12847 T16679 T16682 arg1Of effect,on
R12848 T16679 T16686 arg1Of effect,was
R12849 T16679 T16687 arg2Of effect,confirmed
R12850 T16681 T16680 arg2Of Foxp3,of
R12851 T16529 T16528 arg1Of complexes,Tax-ATF/CREB
R12852 T16532 T16530 arg2Of sequences,onto
R12853 T16685 T16682 arg2Of expression,on
R12854 T16685 T16683 arg1Of expression,HTLV-I
R12855 T16685 T16684 arg1Of expression,gene
R12856 T16687 T16686 arg2Of confirmed,was
R12857 T16688 T16687 arg3Of utilizing,confirmed
R12858 T16532 T16531 arg1Of sequences,specific
R12859 T16536 T16533 arg2Of promoter,in
R12860 T16693 T16688 arg2Of clone,utilizing
R12861 T16693 T16689 arg1Of clone,an
R12862 T16693 T16690 arg1Of clone,HTLV-I
R12863 T16693 T16691 arg1Of clone,infectious
R12864 T16693 T16692 arg1Of clone,molecular
R12865 T16696 T16697 arg1Of we,demonstrated
R12866 T16536 T16534 arg1Of promoter,the
R12867 T16697 T16694 arg1Of demonstrated,Importantly
R12868 T16697 T16695 arg1Of demonstrated,","
R12869 T16536 T16535 arg1Of promoter,viral
R12870 T16536 T16537 arg2Of promoter,known
R12871 T16537 T16538 arg1Of known,as
R12872 T16700 T16699 arg1Of individuals,HTLV-I-infected
R12873 T16700 T16701 arg1Of individuals,with
R12874 T16700 T16715 arg1Of individuals,exhibited
R12875 T16540 T16538 arg2Of elements,as
R12876 T16704 T16701 arg2Of levels,with
R12877 T16704 T16702 arg1Of levels,the
R12878 T16704 T16703 arg1Of levels,highest
R12879 T16704 T16705 arg1Of levels,of
R12880 T16704 T16709 arg1Of levels,within
R12881 T16708 T16705 arg2Of expression,of
R12882 T16708 T16706 arg1Of expression,Foxp3
R12883 T16708 T16707 arg1Of expression,protein
R12884 T16540 T16539 arg1Of elements,Tax-responsive
R12885 T16738 T16735 arg1Of load,the
R12886 T16714 T16709 arg2Of population,within
R12887 T16714 T16710 arg1Of population,the
R12888 T16714 T16711 arg1Of population,CD4+CD25+
R12889 T16714 T16712 arg1Of population,T
R12890 T16714 T16713 arg1Of population,cells
R12891 T16715 T16697 arg2Of exhibited,demonstrated
R12892 T16715 T16698 arg1Of exhibited,that
R12893 T16715 T16722 arg1Of exhibited,with
R12894 T16718 T16715 arg2Of loads,exhibited
R12895 T16718 T16716 arg1Of loads,lower
R12896 T16718 T16717 arg1Of loads,proviral
R12897 T16718 T16719 arg1Of loads,than
R12898 T16720 T16719 arg2Of did,than
R12899 T16721 T16720 arg1Of individuals,did
R12900 T16738 T16736 arg1Of load,HTLV-I
R12901 T16725 T16722 arg2Of levels,with
R12902 T16725 T16723 arg1Of levels,the
R12903 T16725 T16724 arg1Of levels,lowest
R12904 T16725 T16726 arg1Of levels,of
R12905 T16738 T16737 arg1Of load,proviral
R12906 T16738 T16740 arg1Of load,correlates
R12907 T16740 T16733 arg2Of correlates,demonstrated
R12908 T16729 T16726 arg2Of expression,of
R12909 T16729 T16727 arg1Of expression,Foxp3
R12910 T16729 T16728 arg1Of expression,protein
R12911 T16731 T16730 arg1Of studies,Previous
R12912 T16731 T16732 arg1Of studies,have
R12913 T16731 T16733 arg1Of studies,demonstrated
R12914 T16740 T16734 arg1Of correlates,that
R12915 T16733 T16732 arg2Of demonstrated,have
R12916 T16740 T16739 arg1Of correlates,directly
R12917 T16740 T16741 arg1Of correlates,with
R12918 T16740 T16763 arg1Of correlates,[
R12919 T16745 T16742 arg1Of load,HTLV-I
R12920 T16745 T16743 arg1Of load,Tax
R12921 T16745 T16744 arg1Of load,mRNA
R12922 T16834 T16833 arg1Of activation,the
R12923 T16834 T16835 arg1Of activation,of
R12924 T16834 T16839 arg1Of activation,depends
R12925 T16745 T16746 arg1Of load,","
R12926 T16745 T16756 arg1Of load,and
R12927 T16748 T16746 arg2Of frequency,","
R12928 T16838 T16835 arg2Of LTR,of
R12929 T16838 T16836 arg1Of LTR,the
R12930 T16838 T16837 arg1Of LTR,HTLV-I
R12931 T16839 T16832 arg2Of depends,As
R12932 T16839 T16841 arg1Of depends,on
R12933 T16839 T16844 arg1Of depends,(
R12934 T16841 T16840 arg1Of on,primarily
R12935 T16748 T16747 arg1Of frequency,the
R12936 T16843 T16841 arg2Of proteins,on
R12937 T16843 T16842 arg1Of proteins,ATF/CREB
R12938 T16748 T16749 arg1Of frequency,of
R12939 T16754 T16749 arg2Of cells,of
R12940 T16846 T16844 arg2Of in,(
R12941 T16846 T16845 arg1Of in,whether
R12942 T16848 T16847 arg1Of presence,the
R12943 T16848 T16849 arg1Of presence,or
R12944 T16849 T16846 arg2Of or,in
R12945 T16851 T16849 arg2Of absence,or
R12946 T16851 T16850 arg1Of absence,the
R12947 T16851 T16852 arg1Of absence,of
R12948 T16853 T16852 arg2Of Tax,of
R12949 T16854 T16844 arg3Of ),(
R12950 T16856 T16857 arg1Of we,investigated
R12951 T16754 T16750 arg1Of cells,immunopathogenic
R12952 T16754 T16751 arg1Of cells,virus-specific
R12953 T16857 T16832 arg1Of investigated,As
R12954 T16857 T16855 arg1Of investigated,","
R12955 T16754 T16752 arg1Of cells,CD8+
R12956 T16754 T16753 arg1Of cells,T
R12957 T16859 T16860 arg1Of Foxp3,could
R12958 T16859 T16861 arg1Of Foxp3,interact
R12959 T16756 T16741 arg2Of and,with
R12960 T16861 T16857 arg2Of interact,investigated
R12961 T16861 T16858 arg1Of interact,whether
R12962 T16861 T16860 arg2Of interact,could
R12963 T16861 T16862 arg1Of interact,with
R12964 T16756 T16755 arg1Of and,","
R12965 T16758 T16756 arg2Of severity,and
R12966 T16867 T16862 arg2Of pathway,with
R12967 T16867 T16863 arg1Of pathway,this
R12968 T16867 T16864 arg1Of pathway,additional
R12969 T16867 T16865 arg1Of pathway,cellular
R12970 T16867 T16866 arg1Of pathway,signaling
R12971 T16758 T16757 arg1Of severity,disease
R12972 T16871 T16869 arg1Of activity,the
R12973 T16871 T16870 arg1Of activity,DNA-binding
R12974 T16871 T16872 arg1Of activity,of
R12975 T16871 T16874 arg1Of activity,is
R12976 T16873 T16872 arg2Of CREB,of
R12977 T16758 T16759 arg1Of severity,in
R12978 T16874 T16868 arg2Of is,While
R12979 T16874 T16875 arg1Of is,","
R12980 T16874 T16876 arg1Of is,in
R12981 T16874 T16879 arg1Of is,","
R12982 T16760 T16759 arg2Of patients,in
R12983 T16878 T16876 arg2Of cases,in
R12984 T16878 T16877 arg1Of cases,most
R12985 T16880 T16874 arg2Of constitutive,is
R12986 T16760 T16761 arg1Of patients,with
R12987 T16762 T16761 arg2Of HAM/TSP,with
R12988 T16884 T16882 arg1Of potential,the
R12989 T16884 T16883 arg1Of potential,transactivation
R12990 T16884 T16885 arg1Of potential,of
R12991 T16884 T16887 arg1Of potential,is
R12992 T16884 T16888 arg2Of potential,regulated
R12993 T16886 T16885 arg2Of CREB,of
R12994 T16764 T16763 arg2Of 47,[
R12995 T16888 T16868 arg1Of regulated,While
R12996 T16888 T16881 arg1Of regulated,","
R12997 T16888 T16887 arg2Of regulated,is
R12998 T16891 T16888 arg1Of phosphorylation,regulated
R12999 T16891 T16889 arg2Of phosphorylation,by
R13000 T16891 T16890 arg1Of phosphorylation,the
R13001 T16891 T16892 arg1Of phosphorylation,of
R13002 T16893 T16894 arg1Of CREB,and
R13003 T16894 T16892 arg2Of and,of
R13004 T16894 T16896 arg1Of and,of
R13005 T16895 T16894 arg2Of recruitment,and
R13006 T16765 T16763 arg3Of ],[
R13007 T16897 T16896 arg2Of CBP/p300,of
R13008 T16897 T16898 arg1Of CBP/p300,[
R13009 T16899 T16898 arg2Of 48,[
R13010 T16767 T16766 arg1Of results,These
R13011 T16900 T16898 arg3Of ],[
R13012 T16902 T16901 arg1Of data,Our
R13013 T16902 T16903 arg1Of data,demonstrate
R13014 T16767 T16768 arg1Of results,have
R13015 T16905 T16906 arg1Of Foxp3,interferes
R13016 T16770 T16768 arg2Of implications,have
R13017 T16906 T16904 arg1Of interferes,that
R13018 T16906 T16907 arg1Of interferes,with
R13019 T16906 T16914 arg1Of interferes,and
R13020 T16770 T16769 arg1Of implications,important
R13021 T16770 T16771 arg1Of implications,on
R13022 T16773 T16771 arg2Of utility,on
R13023 T16909 T16907 arg2Of latter,with
R13024 T16909 T16908 arg1Of latter,the
R13025 T16909 T16910 arg1Of latter,of
R13026 T16913 T16910 arg2Of processes,of
R13027 T16913 T16911 arg1Of processes,these
R13028 T16913 T16912 arg1Of processes,two
R13029 T16914 T16903 arg2Of and,demonstrate
R13030 T16773 T16772 arg1Of utility,the
R13031 T16915 T16914 arg2Of that,and
R13032 T16773 T16774 arg1Of utility,of
R13033 T16773 T16776 arg1Of utility,in
R13034 T16916 T16925 arg1Of the,resulting
R13035 T16917 T16918 arg1Of recruitment,of
R13036 T16917 T16924 arg1Of recruitment,and
R13037 T16775 T16774 arg2Of Foxp3,of
R13038 T16777 T16776 arg2Of controlling,in
R13039 T16922 T16918 arg2Of p300,of
R13040 T16922 T16919 arg1Of p300,the
R13041 T16922 T16920 arg1Of p300,coactivator
R13042 T16922 T16921 arg1Of p300,protein
R13043 T16924 T16916 arg1Of and,the
R13044 T16924 T16923 arg1Of and,","
R13045 T16924 T16928 arg1Of and,are
R13046 T16924 T16929 arg2Of and,blocked
R13047 T16925 T16924 arg2Of resulting,and
R13048 T16927 T16925 arg2Of activation,resulting
R13049 T16927 T16926 arg1Of activation,transcriptional
R13050 T16929 T16915 arg2Of blocked,that
R13051 T16929 T16928 arg2Of blocked,are
R13052 T16780 T16778 arg1Of expression,viral
R13053 T16780 T16779 arg1Of expression,gene
R13054 T16780 T16781 arg1Of expression,and
R13055 T16781 T16777 arg2Of and,controlling
R13056 T16931 T16929 arg1Of Foxp3,blocked
R13057 T16931 T16930 arg2Of Foxp3,by
R13058 T16932 T16933 arg1Of This,may
R13059 T16932 T16934 arg1Of This,be
R13060 T16783 T16781 arg2Of pathogenesis,and
R13061 T16934 T16933 arg2Of be,may
R13062 T16936 T16934 arg2Of result,be
R13063 T16936 T16935 arg1Of result,the
R13064 T16936 T16937 arg1Of result,of
R13065 T16783 T16782 arg1Of pathogenesis,thus
R13066 T16783 T16784 arg1Of pathogenesis,of
R13067 T16785 T16784 arg2Of HAM/TSP,of
R13068 T16940 T16937 arg2Of interaction,of
R13069 T16940 T16938 arg1Of interaction,the
R13070 T16940 T16939 arg1Of interaction,physical
R13071 T16940 T16942 arg2Of interaction,detected
R13072 T16941 T16942 arg1Of we,detected
R13073 T16942 T16943 arg1Of detected,between
R13074 T16944 T16945 arg1Of Foxp3,and
R13075 T16788 T16789 arg1Of Foxp3,becomes
R13076 T16945 T16943 arg2Of and,between
R13077 T16946 T16945 arg2Of p300,and
R13078 T16947 T16949 arg1Of With,to
R13079 T16947 T16953 arg1Of With,","
R13080 T16948 T16947 arg2Of respect,With
R13081 T16789 T16786 arg1Of becomes,Therefore
R13082 T16952 T16947 arg3Of activity,With
R13083 T16952 T16950 arg1Of activity,HTLV-I
R13084 T16952 T16951 arg1Of activity,LTR
R13085 T16789 T16787 arg1Of becomes,","
R13086 T16954 T16953 arg2Of while,","
R13087 T16789 T16810 arg1Of becomes,","
R13088 T16789 T16812 arg1Of becomes,in
R13089 T16956 T16955 arg1Of Foxp3,full-length
R13090 T16956 T16957 arg1Of Foxp3,inhibited
R13091 T16957 T16954 arg2Of inhibited,while
R13092 T16957 T16963 arg1Of inhibited,by
R13093 T16792 T16789 arg2Of target,becomes
R13094 T16959 T16960 arg1Of basal,and
R13095 T16960 T16958 arg1Of and,both
R13096 T16961 T16960 arg2Of Tax-dependent,and
R13097 T16962 T16957 arg2Of transcription,inhibited
R13098 T16962 T16959 arg1Of transcription,basal
R13099 T16962 T16961 arg1Of transcription,Tax-dependent
R13100 T16965 T16963 arg2Of %,by
R13101 T16965 T16964 arg1Of %,~50
R13102 T16792 T16790 arg1Of target,an
R13103 T16967 T16968 arg1Of ΔFKH,appeared
R13104 T16967 T16970 arg1Of ΔFKH,effective
R13105 T16967 T16972 arg1Of ΔFKH,suppressing
R13106 T16968 T16947 arg1Of appeared,With
R13107 T16968 T16954 arg1Of appeared,while
R13108 T16968 T16966 arg1Of appeared,","
R13109 T16968 T16971 arg1Of appeared,in
R13110 T16792 T16791 arg1Of target,attractive
R13111 T16970 T16968 arg2Of effective,appeared
R13112 T16970 T16969 arg1Of effective,less
R13113 T16792 T16793 arg1Of target,for
R13114 T16972 T16971 arg2Of suppressing,in
R13115 T16795 T16793 arg2Of development,for
R13116 T16972 T16980 arg1Of suppressing,compared
R13117 T16974 T16972 arg2Of activation,suppressing
R13118 T16974 T16973 arg1Of activation,basal
R13119 T16974 T16975 arg1Of activation,(
R13120 T16795 T16794 arg1Of development,the
R13121 T16795 T16796 arg1Of development,of
R13122 T16799 T16796 arg2Of applications,of
R13123 T16976 T16977 arg1Of ~25,%
R13124 T16978 T16975 arg2Of inhibition,(
R13125 T16978 T16976 arg1Of inhibition,~25
R13126 T16979 T16975 arg3Of ),(
R13127 T16799 T16797 arg1Of applications,novel
R13128 T16799 T16798 arg1Of applications,therapeutic
R13129 T16981 T16980 arg2Of to,compared
R13130 T16799 T16800 arg2Of applications,directed
R13131 T16800 T16801 arg1Of directed,at
R13132 T16983 T16981 arg2Of activation,to
R13133 T16983 T16982 arg1Of activation,Tax-dependent
R13134 T16983 T16984 arg1Of activation,(
R13135 T16985 T16986 arg1Of ~50,%
R13136 T16802 T16801 arg2Of modulating,at
R13137 T16987 T16984 arg2Of inhibition,(
R13138 T16987 T16985 arg1Of inhibition,~50
R13139 T16988 T16984 arg3Of ),(
R13140 T16804 T16802 arg2Of expression,modulating
R13141 T16990 T16989 arg1Of effect,The
R13142 T16990 T16991 arg1Of effect,of
R13143 T16990 T16993 arg1Of effect,on
R13144 T16990 T17000 arg1Of effect,in
R13145 T16990 T17004 arg1Of effect,was
R13146 T16990 T17006 arg1Of effect,similar
R13147 T16992 T16991 arg2Of ΔFKH,of
R13148 T16995 T16993 arg2Of activation,on
R13149 T16995 T16994 arg1Of activation,basal
R13150 T16995 T16996 arg1Of activation,of
R13151 T16804 T16803 arg1Of expression,the
R13152 T16999 T16996 arg2Of LTR,of
R13153 T16999 T16997 arg1Of LTR,the
R13154 T16999 T16998 arg1Of LTR,HTLV-I
R13155 T16804 T16805 arg1Of expression,of
R13156 T16809 T16805 arg2Of protein,of
R13157 T17003 T17000 arg2Of cells,in
R13158 T17003 T17001 arg1Of cells,HEK
R13159 T17003 T17002 arg1Of cells,293T
R13160 T17006 T17004 arg2Of similar,was
R13161 T17006 T17005 arg1Of similar,very
R13162 T17006 T17007 arg1Of similar,to
R13163 T17008 T17007 arg2Of that,to
R13164 T17008 T17009 arg2Of that,shown
R13165 T17009 T17010 arg1Of shown,for
R13166 T17009 T17015 arg1Of shown,","
R13167 T16809 T16806 arg1Of protein,this
R13168 T16809 T16807 arg1Of protein,important
R13169 T16809 T16808 arg1Of protein,regulatory
R13170 T17014 T17010 arg2Of reporter,for
R13171 T17014 T17011 arg1Of reporter,a
R13172 T17014 T17012 arg1Of reporter,synthetic
R13173 T17014 T17013 arg1Of reporter,CREB
R13174 T16812 T16811 arg1Of in,especially
R13175 T17016 T17009 arg3Of suggesting,shown
R13176 T16813 T16812 arg2Of light,in
R13177 T17020 T17018 arg1Of domain,the
R13178 T17020 T17019 arg1Of domain,FKH
R13179 T17020 T17021 arg1Of domain,of
R13180 T17020 T17023 arg1Of domain,is
R13181 T17020 T17024 arg1Of domain,important
R13182 T17022 T17021 arg2Of Foxp3,of
R13183 T17023 T17016 arg2Of is,suggesting
R13184 T17023 T17017 arg1Of is,that
R13185 T17024 T17023 arg2Of important,is
R13186 T17024 T17025 arg1Of important,at
R13187 T16813 T16814 arg1Of light,of
R13188 T16816 T16814 arg2Of observations,of
R13189 T16816 T16815 arg1Of observations,recent
R13190 T16819 T16818 arg1Of expression,the
R13191 T17027 T17025 arg2Of level,at
R13192 T17027 T17026 arg1Of level,some
R13193 T16819 T16820 arg1Of expression,of
R13194 T16819 T16822 arg1Of expression,can
R13195 T17029 T17028 arg2Of observed,As
R13196 T17029 T17030 arg1Of observed,with
R13197 T16819 T16824 arg1Of expression,be
R13198 T17032 T17030 arg2Of activation,with
R13199 T17032 T17031 arg1Of activation,NF-κB
R13200 T16819 T16825 arg2Of expression,down-regulated
R13201 T17036 T17034 arg1Of mutant,the
R13202 T17036 T17035 arg1Of mutant,Foxp3
R13203 T17036 T17037 arg1Of mutant,lacking
R13204 T17036 T17041 arg1Of mutant,was
R13205 T16821 T16820 arg2Of Foxp3,of
R13206 T17040 T17037 arg2Of domain,lacking
R13207 T17040 T17038 arg1Of domain,the
R13208 T17040 T17039 arg1Of domain,FKH
R13209 T17041 T17028 arg1Of was,As
R13210 T17041 T17033 arg1Of was,","
R13211 T17041 T17052 arg1Of was,than
R13212 T16825 T16816 arg2Of down-regulated,observations
R13213 T17044 T17041 arg2Of inhibitor,was
R13214 T17044 T17042 arg1Of inhibitor,a
R13215 T17044 T17043 arg1Of inhibitor,stronger
R13216 T17044 T17045 arg1Of inhibitor,of
R13217 T17047 T17045 arg2Of activation,of
R13218 T17047 T17046 arg1Of activation,CREB
R13219 T17047 T17048 arg1Of activation,in
R13220 T17051 T17048 arg2Of cells,in
R13221 T17051 T17049 arg1Of cells,CD4+
R13222 T17051 T17050 arg1Of cells,T
R13223 T16825 T16817 arg1Of down-regulated,that
R13224 T17053 T17052 arg2Of in,than
R13225 T16825 T16822 arg2Of down-regulated,can
R13226 T16825 T16823 arg1Of down-regulated,also
R13227 T16825 T16824 arg2Of down-regulated,be
R13228 T16825 T16829 arg1Of down-regulated,[
R13229 T16828 T16825 arg1Of Tax,down-regulated
R13230 T17057 T17053 arg2Of cells,in
R13231 T17057 T17054 arg1Of cells,HEK
R13232 T17057 T17055 arg1Of cells,293T
R13233 T17057 T17056 arg1Of cells,epithelial
R13234 T16828 T16826 arg2Of Tax,by
R13235 T17060 T17061 arg1Of it,appears
R13236 T16828 T16827 arg1Of Tax,HTLV-I
R13237 T17061 T17058 arg1Of appears,Therefore
R13238 T17061 T17059 arg1Of appears,","
R13239 T16830 T16829 arg2Of 8,[
R13240 T16831 T16829 arg3Of ],[
R13241 T17066 T17063 arg2Of cells,in
R13242 T17066 T17064 arg1Of cells,CD4+
R13243 T17066 T17065 arg1Of cells,T
R13244 T17126 T17123 arg2Of target,as
R13245 T17070 T17068 arg1Of domain,the
R13246 T17070 T17069 arg1Of domain,FKH
R13247 T17070 T17071 arg1Of domain,is
R13248 T17070 T17072 arg1Of domain,dispensable
R13249 T17071 T17061 arg2Of is,appears
R13250 T17071 T17062 arg1Of is,that
R13251 T17071 T17063 arg1Of is,in
R13252 T17071 T17067 arg1Of is,","
R13253 T17072 T17071 arg2Of dispensable,is
R13254 T17072 T17073 arg1Of dispensable,for
R13255 T17072 T17079 arg1Of dispensable,with
R13256 T17076 T17073 arg2Of functioning,for
R13257 T17076 T17074 arg1Of functioning,the
R13258 T17076 T17075 arg1Of functioning,proper
R13259 T17076 T17077 arg1Of functioning,of
R13260 T17078 T17077 arg2Of Foxp3,of
R13261 T17080 T17079 arg2Of respect,with
R13262 T17080 T17081 arg1Of respect,to
R13263 T17083 T17084 arg1Of NF-κB,and
R13264 T17084 T17081 arg2Of and,to
R13265 T17084 T17082 arg1Of and,both
R13266 T17086 T17084 arg2Of activation,and
R13267 T17086 T17085 arg1Of activation,CREB
R13268 T17126 T17124 arg1Of target,a
R13269 T17088 T17087 arg2Of summary,In
R13270 T17126 T17125 arg1Of target,molecular
R13271 T17126 T17127 arg1Of target,of
R13272 T17090 T17091 arg1Of this,is
R13273 T17128 T17127 arg2Of Foxp3,of
R13274 T17091 T17087 arg1Of is,In
R13275 T17091 T17089 arg1Of is,","
R13276 T17091 T17092 arg1Of is,","
R13277 T17091 T17093 arg1Of is,to
R13278 T17091 T17096 arg1Of is,","
R13279 T17095 T17093 arg2Of knowledge,to
R13280 T17095 T17094 arg1Of knowledge,our
R13281 T17130 T17131 arg1Of CREB,has
R13282 T17100 T17091 arg2Of evidence,is
R13283 T17100 T17097 arg1Of evidence,the
R13284 T17100 T17098 arg1Of evidence,first
R13285 T17100 T17099 arg1Of evidence,direct
R13286 T17100 T17101 arg1Of evidence,implicating
R13287 T17103 T17101 arg2Of role,implicating
R13288 T17103 T17102 arg1Of role,a
R13289 T17103 T17104 arg1Of role,for
R13290 T17103 T17110 arg1Of role,in
R13291 T17130 T17132 arg1Of CREB,been
R13292 T17130 T17133 arg2Of CREB,shown
R13293 T17130 T17135 arg1Of CREB,regulate
R13294 T17109 T17104 arg2Of Foxp3,for
R13295 T17109 T17105 arg1Of Foxp3,the
R13296 T17109 T17106 arg1Of Foxp3,Treg-specific
R13297 T17109 T17107 arg1Of Foxp3,transcription
R13298 T17109 T17108 arg1Of Foxp3,factor
R13299 T17111 T17110 arg2Of regulating,in
R13300 T17133 T17129 arg2Of shown,Since
R13301 T17114 T17111 arg2Of expression,regulating
R13302 T17114 T17112 arg1Of expression,retroviral
R13303 T17114 T17113 arg1Of expression,gene
R13304 T17116 T17115 arg2Of addition,In
R13305 T17118 T17119 arg1Of we,identify
R13306 T17119 T17115 arg1Of identify,In
R13307 T17119 T17117 arg1Of identify,","
R13308 T17119 T17123 arg1Of identify,as
R13309 T17133 T17131 arg2Of shown,has
R13310 T17122 T17119 arg2Of pathway,identify
R13311 T17122 T17120 arg1Of pathway,the
R13312 T17122 T17121 arg1Of pathway,CREB
R13313 T17133 T17132 arg2Of shown,been
R13314 T17135 T17133 arg3Of regulate,shown
R13315 T17135 T17134 arg1Of regulate,to
R13316 T17137 T17136 arg1Of genes,multiple
R13317 T17137 T17138 arg2Of genes,involved
R13318 T17137 T17141 arg1Of genes,(
R13319 T17137 T17159 arg1Of genes,","
R13320 T17138 T17139 arg1Of involved,in
R13321 T17221 T17220 arg1Of importance,the
R13322 T17221 T17222 arg1Of importance,of
R13323 T17221 T17244 arg1Of importance,","
R13324 T17221 T17246 arg1Of importance,may
R13325 T17221 T17247 arg1Of importance,limit
R13326 T17221 T17253 arg1Of importance,interfering
R13327 T17224 T17223 arg1Of expression,Foxp3
R13328 T17224 T17225 arg1Of expression,and
R13329 T17140 T17139 arg2Of transcription,in
R13330 T17225 T17222 arg2Of and,of
R13331 T17225 T17228 arg1Of and,in
R13332 T17227 T17225 arg2Of function,and
R13333 T17227 T17226 arg1Of function,Treg
R13334 T17144 T17145 arg1Of JunD,","
R13335 T17230 T17231 arg1Of development,and
R13336 T17231 T17228 arg2Of and,in
R13337 T17231 T17229 arg1Of and,the
R13338 T17231 T17233 arg1Of and,of
R13339 T17232 T17231 arg2Of maintenance,and
R13340 T17235 T17233 arg2Of immunity,of
R13341 T17235 T17234 arg1Of immunity,protective
R13342 T17235 T17236 arg1Of immunity,against
R13343 T17235 T17240 arg1Of immunity,Based
R13344 T17237 T17238 arg1Of HIV-1,and
R13345 T17145 T17147 arg1Of ",",","
R13346 T17238 T17236 arg2Of and,against
R13347 T17239 T17238 arg2Of HTLV-I.,and
R13348 T17241 T17240 arg2Of on,Based
R13349 T17146 T17145 arg2Of c-Fos,","
R13350 T17243 T17241 arg2Of findings,on
R13351 T17243 T17242 arg1Of findings,recent
R13352 T17245 T17244 arg2Of Foxp3,","
R13353 T17148 T17147 arg2Of signal,","
R13354 T17247 T17219 arg2Of limit,stresses
R13355 T17247 T17246 arg2Of limit,may
R13356 T17247 T17252 arg1Of limit,by
R13357 T17248 T17249 arg1Of HIV-1,and
R13358 T17250 T17249 arg2Of HTLV-I,and
R13359 T17149 T17141 arg2Of transducer,(
R13360 T17251 T17247 arg2Of transcription,limit
R13361 T17251 T17248 arg1Of transcription,HIV-1
R13362 T17251 T17250 arg1Of transcription,HTLV-I
R13363 T17253 T17252 arg2Of interfering,by
R13364 T17253 T17254 arg1Of interfering,with
R13365 T17149 T17142 arg1Of transducer,e.g.
R13366 T17149 T17143 arg1Of transducer,","
R13367 T17255 T17254 arg2Of activation,with
R13368 T17255 T17256 arg1Of activation,of
R13369 T17149 T17144 arg1Of transducer,JunD
R13370 T17257 T17258 arg1Of NF-κB,and
R13371 T17149 T17146 arg1Of transducer,c-Fos
R13372 T17149 T17148 arg1Of transducer,signal
R13373 T17259 T17258 arg2Of CREB,and
R13374 T17149 T17150 arg1Of transducer,of
R13375 T17260 T17256 arg2Of pathways,of
R13376 T17260 T17257 arg1Of pathways,NF-κB
R13377 T17260 T17259 arg1Of pathways,CREB
R13378 T17149 T17154 arg1Of transducer,3
R13379 T17149 T17155 arg1Of transducer,[
R13380 T17153 T17150 arg2Of cells,of
R13381 T17267 T17265 arg1Of effect,this
R13382 T17267 T17266 arg1Of effect,inhibitory
R13383 T17267 T17268 arg1Of effect,is
R13384 T17267 T17270 arg1Of effect,absolute
R13385 T17268 T17263 arg2Of is,observing
R13386 T17268 T17264 arg1Of is,that
R13387 T17268 T17269 arg1Of is,not
R13388 T17270 T17268 arg2Of absolute,is
R13389 T17153 T17151 arg2Of cells,activated
R13390 T17153 T17152 arg1Of cells,T
R13391 T17156 T17155 arg2Of STAT3,[
R13392 T17274 T17263 arg1Of level,observing
R13393 T17274 T17272 arg1Of level,a
R13394 T17274 T17273 arg1Of level,low
R13395 T17274 T17275 arg1Of level,of
R13396 T17274 T17279 arg1Of level,may
R13397 T17274 T17280 arg1Of level,persist
R13398 T17274 T17302 arg1Of level,result
R13399 T17157 T17155 arg3Of ],[
R13400 T17278 T17275 arg2Of expression,of
R13401 T17278 T17276 arg1Of expression,viral
R13402 T17278 T17277 arg1Of expression,gene
R13403 T17280 T17279 arg2Of persist,may
R13404 T17280 T17281 arg1Of persist,in
R13405 T17280 T17301 arg1Of persist,and
R13406 T17158 T17141 arg3Of ),(
R13407 T17159 T17162 arg1Of ",",(
R13408 T17284 T17281 arg2Of cells,in
R13409 T17284 T17282 arg1Of cells,CD4+
R13410 T17284 T17283 arg1Of cells,T
R13411 T17284 T17285 arg1Of cells,(
R13412 T17159 T17174 arg1Of ",",and
R13413 T17287 T17286 arg2Of particular,in
R13414 T17161 T17159 arg2Of cycle,","
R13415 T17290 T17285 arg2Of cells,(
R13416 T17290 T17286 arg1Of cells,in
R13417 T17290 T17288 arg1Of cells,regulatory
R13418 T17290 T17289 arg1Of cells,T
R13419 T17290 T17291 arg1Of cells,","
R13420 T17290 T17292 arg1Of cells,which
R13421 T17290 T17293 arg1Of cells,are
R13422 T17161 T17160 arg1Of cycle,cell
R13423 T17165 T17166 arg1Of p15INK4b,","
R13424 T17295 T17293 arg2Of reservoirs,are
R13425 T17295 T17294 arg2Of reservoirs,known
R13426 T17295 T17296 arg1Of reservoirs,of
R13427 T17297 T17298 arg1Of HIV-1,and
R13428 T17298 T17296 arg2Of and,of
R13429 T17299 T17298 arg2Of HTLV-I,and
R13430 T17300 T17285 arg3Of ),(
R13431 T17301 T17261 arg1Of and,However
R13432 T17301 T17262 arg1Of and,","
R13433 T17301 T17263 modOf and,observing
R13434 T17301 T17271 arg1Of and,","
R13435 T17302 T17301 arg2Of result,and
R13436 T17302 T17303 arg1Of result,in
R13437 T17166 T17162 arg2Of ",",(
R13438 T17305 T17303 arg2Of accumulation,in
R13439 T17305 T17304 arg1Of accumulation,the
R13440 T17305 T17306 arg1Of accumulation,of
R13441 T17166 T17163 arg1Of ",",e.g.
R13442 T17166 T17164 arg1Of ",",","
R13443 T17308 T17306 arg2Of proteins,of
R13444 T17308 T17307 arg1Of proteins,viral
R13445 T17308 T17309 arg1Of proteins,that
R13446 T17308 T17311 arg1Of proteins,stimulate
R13447 T17308 T17318 arg1Of proteins,inhibit
R13448 T17311 T17316 arg1Of stimulate,or
R13449 T17312 T17313 arg1Of NF-κB,and/or
R13450 T17166 T17169 arg1Of ",",","
R13451 T17168 T17166 arg2Of A,","
R13452 T17314 T17313 arg2Of CREB,and/or
R13453 T17315 T17311 arg2Of activation,stimulate
R13454 T17315 T17312 arg1Of activation,NF-κB
R13455 T17315 T17314 arg1Of activation,CREB
R13456 T17316 T17310 arg1Of or,either
R13457 T17168 T17167 arg1Of A,cyclin
R13458 T17171 T17169 arg2Of D1,","
R13459 T17318 T17316 arg2Of inhibit,or
R13460 T17318 T17317 arg1Of inhibit,directly
R13461 T17171 T17170 arg1Of D1,cyclin
R13462 T17172 T17162 arg3Of ),(
R13463 T17320 T17321 arg1Of expression,or
R13464 T17321 T17318 arg2Of or,inhibit
R13465 T17321 T17319 arg1Of or,Foxp3
R13466 T17322 T17321 arg2Of function,or
R13467 T17174 T17135 arg2Of and,regulate
R13468 T17324 T17323 arg1Of imbalance,The
R13469 T17324 T17325 arg1Of imbalance,of
R13470 T17324 T17336 arg1Of imbalance,may
R13471 T17324 T17337 arg1Of imbalance,be
R13472 T17326 T17327 arg1Of NF-κB,and
R13473 T17174 T17173 arg1Of and,","
R13474 T17328 T17327 arg2Of CREB,and
R13475 T17176 T17174 arg2Of regulation,and
R13476 T17329 T17325 arg2Of activation,of
R13477 T17329 T17326 arg1Of activation,NF-κB
R13478 T17329 T17328 arg1Of activation,CREB
R13479 T17329 T17330 arg2Of activation,caused
R13480 T17176 T17175 arg1Of regulation,immune
R13481 T17176 T17177 arg1Of regulation,(
R13482 T17176 T17188 arg1Of regulation,(
R13483 T17180 T17181 arg1Of IL-2,","
R13484 T17335 T17330 arg1Of products,caused
R13485 T17335 T17331 arg2Of products,by
R13486 T17335 T17332 arg1Of products,these
R13487 T17335 T17333 arg1Of products,viral
R13488 T17335 T17334 arg1Of products,gene
R13489 T17181 T17178 arg1Of ",",e.g.
R13490 T17337 T17336 arg2Of be,may
R13491 T17181 T17179 arg1Of ",",","
R13492 T17340 T17337 arg2Of step,be
R13493 T17340 T17338 arg1Of step,a
R13494 T17340 T17339 arg1Of step,crucial
R13495 T17340 T17341 arg1Of step,in
R13496 T17181 T17183 arg1Of ",",","
R13497 T17182 T17181 arg2Of IL-6,","
R13498 T17343 T17341 arg2Of pathogenesis,in
R13499 T17343 T17342 arg1Of pathogenesis,the
R13500 T17343 T17344 arg1Of pathogenesis,of
R13501 T17183 T17177 arg2Of ",",(
R13502 T17347 T17344 arg2Of disorders,of
R13503 T17347 T17345 arg1Of disorders,virus-induced
R13504 T17347 T17346 arg1Of disorders,immunological
R13505 T17347 T17349 arg1Of disorders,as
R13506 T17186 T17183 arg2Of α,","
R13507 T17349 T17348 arg1Of as,such
R13508 T17350 T17351 arg1Of AIDS,and
R13509 T17351 T17349 arg2Of and,as
R13510 T17352 T17351 arg2Of HAM/TSP,and
R13511 T17186 T17184 arg1Of α,T-cell
R13512 T17186 T17185 arg1Of α,receptor
R13513 T17354 T17353 arg1Of studies,Future
R13514 T17354 T17355 arg1Of studies,will
R13515 T17354 T17356 arg1Of studies,be
R13516 T17354 T17357 arg2Of studies,directed
R13517 T17354 T17379 arg1Of studies,address
R13518 T17354 T17384 arg1Of studies,guide
R13519 T17187 T17177 arg3Of ),(
R13520 T17357 T17355 arg2Of directed,will
R13521 T17357 T17356 arg2Of directed,be
R13522 T17357 T17358 arg1Of directed,at
R13523 T17357 T17374 arg1Of directed,","
R13524 T17357 T17375 arg1Of directed,in
R13525 T17359 T17360 arg1Of identifying,and
R13526 T17360 T17358 arg2Of and,at
R13527 T17361 T17360 arg2Of characterizing,and
R13528 T17189 T17188 arg2Of reviewed,(
R13529 T17363 T17359 arg2Of proteins,identifying
R13530 T17363 T17361 arg2Of proteins,characterizing
R13531 T17363 T17362 arg1Of proteins,cellular
R13532 T17363 T17364 arg1Of proteins,that
R13533 T17363 T17365 arg1Of proteins,interact
R13534 T17365 T17366 arg1Of interact,with
R13535 T17365 T17369 arg1Of interact,in
R13536 T17189 T17190 arg1Of reviewed,in
R13537 T17367 T17366 arg2Of Foxp3,with
R13538 T17189 T17191 arg1Of reviewed,[
R13539 T17192 T17191 arg2Of 48,[
R13540 T17369 T17368 arg1Of in,both
R13541 T17371 T17372 arg1Of nucleus,and
R13542 T17372 T17369 arg2Of and,in
R13543 T17372 T17370 arg1Of and,the
R13544 T17373 T17372 arg2Of cytoplasm,and
R13545 T17193 T17191 arg3Of ],[
R13546 T17376 T17375 arg2Of order,in
R13547 T17194 T17188 arg3Of ),(
R13548 T17379 T17375 arg3Of address,in
R13549 T17379 T17377 arg1Of address,to
R13550 T17379 T17378 arg1Of address,better
R13551 T17379 T17383 modOf address,to
R13552 T17382 T17379 arg2Of functions,address
R13553 T17382 T17380 arg1Of functions,how
R13554 T17382 T17381 arg1Of functions,Foxp3
R13555 T17197 T17196 arg1Of findings,the
R13556 T17384 T17383 arg1Of guide,to
R13557 T17386 T17387 arg1Of development,and
R13558 T17387 T17384 arg2Of and,guide
R13559 T17387 T17385 arg1Of and,the
R13560 T17387 T17389 arg1Of and,of
R13561 T17388 T17387 arg2Of function,and
R13562 T17197 T17198 arg2Of findings,presented
R13563 T17197 T17202 arg1Of findings,broaden
R13564 T17392 T17389 arg2Of cells,of
R13565 T17392 T17390 arg1Of cells,regulatory
R13566 T17392 T17391 arg1Of cells,T
R13567 T17392 T17393 arg1Of cells,in
R13568 T17198 T17199 arg1Of presented,in
R13569 T17394 T17395 arg1Of health,and
R13570 T17395 T17393 arg2Of and,in
R13571 T17201 T17199 arg2Of report,in
R13572 T17396 T17395 arg2Of disease,and
R13573 T17201 T17200 arg1Of report,this
R13574 T17202 T17129 arg1Of broaden,Since
R13575 T17202 T17195 arg1Of broaden,","
R13576 T17202 T17209 arg1Of broaden,under
R13577 T17205 T17202 arg2Of range,broaden
R13578 T17205 T17203 arg1Of range,the
R13579 T17205 T17204 arg1Of range,potential
R13580 T17205 T17206 arg1Of range,of
R13581 T17208 T17206 arg2Of pathways,of
R13584 T17208 T17207 arg1Of pathways,signaling
R13586 T17211 T17209 arg2Of control,under
R13597 T17211 T17210 arg1Of control,the
R13598 T17211 T17212 arg1Of control,of
R13599 T17216 T17212 arg2Of Foxp3,of
R13600 T17216 T17213 arg1Of Foxp3,the
R13601 T17216 T17214 arg1Of Foxp3,regulatory
R13602 T17216 T17215 arg1Of Foxp3,protein
R13603 T17218 T17217 arg1Of evidence,Our
R13604 T17218 T17219 arg1Of evidence,stresses
R14184 T18819 T18818 arg1Of culture,Cell
R14185 T18822 T18820 arg1Of cells,HEK
R14186 T18822 T18821 arg1Of cells,293T
R14187 T18822 T18823 arg1Of cells,were
R14188 T18822 T18824 arg2Of cells,cultured
R14189 T18824 T18823 arg2Of cultured,were
R14190 T18824 T18825 arg1Of cultured,in
R14191 T18826 T18827 arg2Of Dulbecco,'s
R14192 T18830 T18825 arg2Of medium,in
R14193 T18830 T18827 arg1Of medium,'s
R14194 T18830 T18828 arg1Of medium,modified
R14195 T18830 T18829 arg1Of medium,Eagle
R14196 T18830 T18831 arg1Of medium,(
R14197 T18832 T18831 arg2Of Invitrogen,(
R14198 T18832 T18833 arg1Of Invitrogen,","
R14199 T18832 T18837 arg1Of Invitrogen,","
R14200 T18834 T18835 arg1Of Carlsbad,","
R14201 T18835 T18833 arg2Of ",",","
R14202 T18836 T18835 arg2Of California,","
R14203 T18839 T18837 arg2Of States,","
R14204 T18839 T18838 arg1Of States,United
R14205 T18840 T18831 arg3Of ),(
R14206 T18843 T18841 arg1Of cells,Jurkat
R14207 T18843 T18842 arg1Of cells,T
R14208 T18843 T18844 arg1Of cells,and
R14209 T18844 T18850 arg1Of and,were
R14210 T18844 T18851 arg2Of and,cultured
R14211 T18849 T18844 arg2Of cells,and
R14212 T18849 T18845 arg1Of cells,primary
R14213 T18849 T18846 arg1Of cells,human
R14214 T18849 T18847 arg1Of cells,CD4+
R14215 T18849 T18848 arg1Of cells,T
R14216 T18851 T18850 arg2Of cultured,were
R14217 T18851 T18852 arg1Of cultured,in
R14218 T18854 T18852 arg2Of medium,in
R14219 T18854 T18853 arg1Of medium,RPMI-1640
R14220 T18854 T18855 arg1Of medium,(
R14221 T18856 T18855 arg2Of Invitrogen,(
R14222 T18857 T18855 arg3Of ),(
R14223 T18858 T18859 arg1Of Media,were
R14224 T18858 T18860 arg2Of Media,supplemented
R14225 T18860 T18859 arg2Of supplemented,were
R14226 T18860 T18861 arg1Of supplemented,with
R14227 T18862 T18863 arg1Of 2,mM
R14228 T18864 T18862 arg1Of L-glutamine,2
R14229 T18864 T18865 arg1Of L-glutamine,","
R14230 T18865 T18869 arg1Of ",",","
R14231 T18868 T18865 arg2Of penicillin,","
R14232 T18868 T18866 arg1Of penicillin,100
R14233 T18868 T18867 arg1Of penicillin,U/ml
R14234 T18869 T18873 arg1Of ",",(
R14235 T18869 T18886 arg1Of ",",and
R14236 T18872 T18869 arg2Of streptomycin,","
R14237 T18872 T18870 arg1Of streptomycin,100
R14238 T18872 T18871 arg1Of streptomycin,μg/ml
R14239 T18874 T18875 arg1Of Cambrex,","
R14240 T18875 T18878 arg1Of ",",","
R14241 T18877 T18875 arg2Of Rutherford,","
R14242 T18877 T18876 arg1Of Rutherford,East
R14243 T18878 T18881 arg1Of ",",","
R14244 T18880 T18878 arg2Of Jersey,","
R14245 T18880 T18879 arg1Of Jersey,New
R14246 T18881 T18873 arg2Of ",",(
R14247 T18883 T18881 arg2Of States,","
R14248 T18883 T18882 arg1Of States,United
R14249 T18884 T18873 arg3Of ),(
R14250 T18886 T18861 arg2Of and,with
R14251 T18886 T18885 arg1Of and,","
R14252 T18886 T18892 arg1Of and,(
R14253 T18887 T18888 arg1Of 10,%
R14254 T18891 T18886 arg2Of serum,and
R14255 T18891 T18887 arg1Of serum,10
R14256 T18891 T18889 arg1Of serum,fetal
R14257 T18891 T18890 arg1Of serum,bovine
R14258 T18894 T18893 arg1Of Biologicals,Atlanta
R14259 T18894 T18895 arg1Of Biologicals,","
R14260 T18895 T18897 arg1Of ",",","
R14261 T18896 T18895 arg2Of Norcross,","
R14262 T18897 T18899 arg1Of ",",","
R14263 T18898 T18897 arg2Of Georgia,","
R14264 T18899 T18892 arg2Of ",",(
R14265 T18901 T18899 arg2Of States,","
R14266 T18901 T18900 arg1Of States,United
R14267 T18902 T18892 arg3Of ),(
R14383 T19040 T19041 arg1Of Patients,and
R14384 T19043 T19041 arg2Of preparation,and
R14385 T19043 T19042 arg1Of preparation,cell
R14386 T19044 T19045 arg1Of PBMCs,were
R14387 T19044 T19046 arg2Of PBMCs,prepared
R14388 T19046 T19045 arg2Of prepared,were
R14389 T19046 T19070 arg1Of prepared,and
R14390 T19048 T19046 arg1Of centrifugation,prepared
R14391 T19048 T19047 arg2Of centrifugation,by
R14392 T19048 T19049 arg1Of centrifugation,over
R14393 T19051 T19049 arg2Of gradients,over
R14394 T19051 T19050 arg1Of gradients,Ficoll-Hypaque
R14395 T19051 T19052 arg1Of gradients,(
R14396 T19051 T19062 arg1Of gradients,from
R14397 T19053 T19054 arg1Of BioWhittaker,","
R14398 T19054 T19056 arg1Of ",",","
R14399 T19055 T19054 arg2Of Walkersville,","
R14400 T19056 T19058 arg1Of ",",","
R14401 T19057 T19056 arg2Of Maryland,","
R14402 T19059 T19058 arg2Of United,","
R14403 T19060 T19052 arg2Of States,(
R14404 T19060 T19053 arg1Of States,BioWhittaker
R14405 T19060 T19055 arg1Of States,Walkersville
R14406 T19060 T19057 arg1Of States,Maryland
R14407 T19060 T19059 arg1Of States,United
R14408 T19061 T19052 arg3Of ),(
R14409 T19065 T19063 arg1Of patients,eight
R14410 T19065 T19064 arg1Of patients,HAM/TSP
R14411 T19065 T19066 arg1Of patients,and
R14412 T19066 T19062 arg2Of and,from
R14413 T19068 T19066 arg2Of ACs,and
R14414 T19068 T19067 arg1Of ACs,eight
R14415 T19070 T19069 arg1Of and,","
R14416 T19072 T19071 arg1Of cells,the
R14417 T19072 T19073 arg1Of cells,were
R14418 T19072 T19075 arg2Of cells,cryopreserved
R14419 T19075 T19070 arg2Of cryopreserved,and
R14420 T19075 T19073 arg2Of cryopreserved,were
R14421 T19075 T19074 arg1Of cryopreserved,viably
R14422 T19075 T19076 arg1Of cryopreserved,in
R14423 T19075 T19079 arg1Of cryopreserved,until
R14424 T19078 T19076 arg2Of nitrogen,in
R14425 T19078 T19077 arg1Of nitrogen,liquid
R14426 T19080 T19079 arg2Of tested,until
R14427 T19081 T19082 arg1Of HAM/TSP,was
R14428 T19081 T19083 arg2Of HAM/TSP,diagnosed
R14429 T19083 T19082 arg2Of diagnosed,was
R14430 T19083 T19084 arg1Of diagnosed,according
R14431 T19085 T19084 arg2Of to,according
R14432 T19087 T19085 arg2Of guidelines,to
R14433 T19087 T19086 arg1Of guidelines,WHO
R14434 T19087 T19088 arg1Of guidelines,[
R14435 T19089 T19088 arg2Of 49,[
R14436 T19090 T19088 arg3Of ],[
R14437 T19092 T19091 arg1Of seropositivity,HTLV-I
R14438 T19092 T19093 arg1Of seropositivity,was
R14439 T19092 T19094 arg2Of seropositivity,determined
R14440 T19094 T19093 arg2Of determined,was
R14441 T19094 T19097 arg1Of determined,(
R14442 T19094 T19109 arg1Of determined,","
R14443 T19094 T19110 arg1Of determined,with
R14444 T19096 T19094 arg1Of ELISA,determined
R14445 T19096 T19095 arg2Of ELISA,by
R14446 T19099 T19098 arg1Of Laboratories,Abbott
R14447 T19099 T19100 arg1Of Laboratories,","
R14448 T19100 T19103 arg1Of ",",","
R14449 T19102 T19100 arg2Of Park,","
R14450 T19102 T19101 arg1Of Park,Abbott
R14451 T19103 T19105 arg1Of ",",","
R14452 T19104 T19103 arg2Of Illinois,","
R14453 T19105 T19097 arg2Of ",",(
R14454 T19107 T19105 arg2Of States,","
R14455 T19107 T19106 arg1Of States,United
R14456 T19108 T19097 arg3Of ),(
R14457 T19111 T19110 arg2Of confirmation,with
R14458 T19111 T19112 arg1Of confirmation,by
R14459 T19115 T19112 arg2Of analysis,by
R14460 T19115 T19113 arg1Of analysis,Western
R14461 T19115 T19114 arg1Of analysis,blot
R14462 T19115 T19116 arg1Of analysis,(
R14463 T19118 T19116 arg2Of Technologies,(
R14464 T19118 T19117 arg1Of Technologies,Genelabs
R14465 T19118 T19119 arg1Of Technologies,","
R14466 T19118 T19124 arg1Of Technologies,","
R14467 T19121 T19119 arg2Of City,","
R14468 T19121 T19120 arg1Of City,Redwood
R14469 T19121 T19122 arg1Of City,","
R14470 T19123 T19122 arg2Of California,","
R14471 T19126 T19124 arg2Of States,","
R14472 T19126 T19125 arg1Of States,United
R14473 T19127 T19116 arg3Of ),(
R14474 T19129 T19128 arg1Of samples,Blood
R14475 T19129 T19130 arg1Of samples,were
R14476 T19129 T19131 arg2Of samples,obtained
R14477 T19129 T19143 arg2Of samples,approved
R14478 T19131 T19132 arg1Of obtained,after
R14479 T19131 T19135 arg1Of obtained,as
R14480 T19131 T19142 arg1Of obtained,and
R14481 T19134 T19132 arg2Of consent,after
R14482 T19134 T19133 arg2Of consent,informed
R14483 T19136 T19135 arg2Of part,as
R14484 T19136 T19137 arg1Of part,of
R14485 T19140 T19137 arg2Of protocol,of
R14486 T19140 T19138 arg1Of protocol,a
R14487 T19140 T19139 arg1Of protocol,clinical
R14488 T19140 T19141 arg2Of protocol,reviewed
R14489 T19142 T19130 arg2Of and,were
R14490 T19143 T19142 arg2Of approved,and
R14491 T19149 T19143 arg1Of panel,approved
R14492 T19149 T19144 arg2Of panel,by
R14493 T19149 T19145 arg1Of panel,the
R14494 T19149 T19146 arg1Of panel,NIH
R14495 T19149 T19147 arg1Of panel,institutional
R14496 T19149 T19148 arg1Of panel,review
R1466 T1833 T1832 arg1Of tolerance,Immunological
R1467 T1833 T1834 arg1Of tolerance,to
R1468 T1833 T1836 arg1Of tolerance,is
R1469 T1835 T1834 arg2Of self-antigens,to
R1470 T1836 T1870 arg1Of is,[
R1471 T1838 T1837 arg1Of result,the
R1472 T1838 T1839 arg1Of result,of
R1473 T1838 T1853 arg1Of result,and
R1474 T1841 T1839 arg2Of deletion,of
R1475 T1841 T1840 arg1Of deletion,the
R1476 T1841 T1842 arg1Of deletion,of
R1477 T1845 T1842 arg2Of lymphocytes,of
R1478 T1845 T1843 arg1Of lymphocytes,self-reactive
R1479 T1845 T1844 arg1Of lymphocytes,T
R1480 T1845 T1846 arg1Of lymphocytes,in
R1481 T1848 T1846 arg2Of thymus,in
R1482 T1848 T1847 arg1Of thymus,the
R1483 T1848 T1849 arg1Of thymus,(
R1484 T1851 T1849 arg2Of tolerance,(
R1485 T1851 T1850 arg1Of tolerance,central
R1486 T1852 T1849 arg3Of ),(
R1487 T1853 T1836 arg2Of and,is
R1488 T1854 T1853 arg2Of suppression,and
R14881 T19777 T19778 arg1Of Isolation,of
R14882 T19783 T19778 arg2Of cells,of
R14883 T19783 T19779 arg1Of cells,primary
R14884 T19783 T19780 arg1Of cells,human
R14885 T19783 T19781 arg1Of cells,CD4+
R14886 T19783 T19782 arg1Of cells,T
R14887 T19786 T19784 arg1Of cells,CD4+
R14888 T19786 T19785 arg1Of cells,T
R14889 T19786 T19787 arg1Of cells,were
R1489 T1854 T1855 arg1Of suppression,of
R14890 T19786 T19788 arg2Of cells,isolated
R14891 T19788 T19787 arg2Of isolated,were
R14892 T19788 T19789 arg1Of isolated,from
R14893 T19788 T19794 arg1Of isolated,by
R14894 T19788 T19797 arg1Of isolated,with
R14895 T19788 T19814 arg1Of isolated,according
R14896 T19793 T19789 arg2Of PBMCs,from
R14897 T19793 T19790 arg2Of PBMCs,cryopreserved
R14898 T19793 T19791 arg1Of PBMCs,healthy
R14899 T19793 T19792 arg1Of PBMCs,donor
R1490 T1857 T1855 arg2Of activation,of
R14900 T19796 T19794 arg2Of selection,by
R14901 T19796 T19795 arg1Of selection,negative
R14902 T19803 T19797 arg2Of Kit,with
R14903 T19803 T19798 arg1Of Kit,the
R14904 T19803 T19799 arg1Of Kit,CD4+
R14905 T19803 T19800 arg1Of Kit,T
R14906 T19803 T19801 arg1Of Kit,Cell
R14907 T19803 T19802 arg1Of Kit,Isolation
R14908 T19803 T19804 arg1Of Kit,II
R14909 T19803 T19805 arg1Of Kit,(
R1491 T1857 T1856 arg1Of activation,the
R14910 T19807 T19805 arg2Of Biotech,(
R14911 T19807 T19806 arg1Of Biotech,Miltenyi
R14912 T19807 T19808 arg1Of Biotech,","
R14913 T19810 T19808 arg2Of Gladbach,","
R14914 T19810 T19809 arg1Of Gladbach,Bergisch
R14915 T19810 T19811 arg1Of Gladbach,","
R14916 T19812 T19811 arg2Of Germany,","
R14917 T19813 T19805 arg3Of ),(
R14918 T19815 T19814 arg2Of to,according
R14919 T19816 T19817 arg2Of manufacturer,'s
R1492 T1857 T1858 arg1Of activation,of
R14920 T19818 T19815 arg2Of guidelines,to
R14921 T19818 T19817 arg1Of guidelines,'s
R14922 T19819 T19820 arg1Of Purity,of
R14923 T19819 T19826 arg1Of Purity,was
R14924 T19819 T19828 arg1Of Purity,higher
R14925 T19822 T19821 arg1Of selected,negatively
R14926 T19825 T19820 arg2Of cells,of
R14927 T19825 T19822 arg1Of cells,selected
R14928 T19825 T19823 arg1Of cells,CD4+
R14929 T19825 T19824 arg1Of cells,T
R1493 T1857 T1863 arg1Of activation,in
R14930 T19826 T19832 arg1Of was,as
R14931 T19828 T19826 arg2Of higher,was
R14932 T19828 T19827 arg1Of higher,consistently
R14933 T19828 T19829 arg1Of higher,than
R14934 T19831 T19829 arg2Of %,than
R14935 T19831 T19830 arg1Of %,96
R14936 T19833 T19832 arg2Of determined,as
R14937 T19836 T19833 arg1Of cytometry,determined
R14938 T19836 T19834 arg2Of cytometry,by
R14939 T19836 T19835 arg1Of cytometry,flow
R1494 T1860 T1859 arg1Of self-reactive,potentially
R1495 T1862 T1858 arg2Of lymphocytes,of
R1496 T1862 T1860 arg1Of lymphocytes,self-reactive
R1497 T1862 T1861 arg1Of lymphocytes,T
R1498 T1865 T1863 arg2Of periphery,in
R1499 T1865 T1864 arg1Of periphery,the
R1500 T1865 T1866 arg1Of periphery,(
R1501 T1868 T1866 arg2Of tolerance,(
R1502 T1868 T1867 arg1Of tolerance,peripheral
R1503 T1869 T1866 arg3Of ),(
R1504 T1871 T1870 arg2Of 1,[
R1505 T1872 T1870 arg3Of ],[
R1506 T1873 T1874 arg1Of Suppression,of
R1507 T1873 T1879 arg1Of Suppression,is
R1508 T1873 T1880 arg2Of Suppression,mediated
R1509 T1878 T1874 arg2Of responses,of
R1510 T1878 T1875 arg1Of responses,pathogenic
R1511 T1878 T1876 arg1Of responses,T
R1512 T1878 T1877 arg1Of responses,cell
R1513 T1880 T1879 arg2Of mediated,is
R1514 T1880 T1891 arg1Of mediated,[
R1515 T1883 T1882 arg1Of arising,naturally
R1516 T1887 T1880 arg1Of cells,mediated
R1517 T1887 T1881 arg2Of cells,by
R1518 T1887 T1883 arg1Of cells,arising
R1519 T1887 T1884 arg1Of cells,CD4+CD25+
R1520 T1887 T1885 arg1Of cells,T
R1521 T1887 T1886 arg1Of cells,regulatory
R1522 T1887 T1888 arg1Of cells,(
R1523 T1889 T1888 arg2Of Tregs,(
R15239 T20208 T20209 arg1Of expression,and
R1524 T1890 T1888 arg3Of ),(
R15240 T20210 T20209 arg2Of luciferase,and
R15241 T20211 T20207 arg1Of assays,Transient
R15242 T20211 T20208 arg1Of assays,expression
R15243 T20211 T20210 arg1Of assays,luciferase
R15244 T20214 T20212 arg1Of cells,HEK
R15245 T20214 T20213 arg1Of cells,293T
R15246 T20214 T20215 arg1Of cells,were
R15247 T20214 T20216 arg2Of cells,plated
R15248 T20216 T20215 arg2Of plated,were
R15249 T20216 T20217 arg1Of plated,at
R1525 T1892 T1891 arg2Of "2,3",[
R15250 T20219 T20217 arg2Of density,at
R15251 T20219 T20218 arg1Of density,a
R15252 T20219 T20220 arg1Of density,of
R15253 T20219 T20225 arg1Of density,in
R15254 T20223 T20222 arg1Of 105,×
R15255 T20224 T20220 arg2Of cells/well,of
R15256 T20224 T20221 arg1Of cells/well,5
R15257 T20224 T20223 arg1Of cells/well,105
R15258 T20228 T20225 arg2Of plates,in
R15259 T20228 T20226 arg1Of plates,six-well
R1526 T1893 T1891 arg3Of ],[
R15260 T20228 T20227 arg1Of plates,culture
R15261 T20228 T20229 arg1Of plates,(
R15262 T20231 T20232 arg1Of Biosciences,","
R15263 T20232 T20235 arg1Of ",",","
R15264 T20234 T20232 arg2Of Diego,","
R15265 T20234 T20233 arg1Of Diego,San
R15266 T20235 T20230 arg1Of ",",BD
R15267 T20235 T20237 arg1Of ",",","
R15268 T20236 T20235 arg2Of California,","
R15269 T20237 T20229 arg2Of ",",(
R1527 T1894 T1895 arg1Of Deficiencies,in
R15270 T20239 T20237 arg2Of States,","
R15271 T20239 T20238 arg1Of States,United
R15272 T20240 T20229 arg3Of ),(
R15273 T20242 T20217 arg3Of d,at
R15274 T20242 T20241 arg1Of d,1
R15275 T20242 T20243 arg1Of d,prior
R15276 T20243 T20244 arg1Of prior,to
R15277 T20245 T20244 arg2Of transfection,to
R15278 T20245 T20246 arg1Of transfection,with
R15279 T20250 T20246 arg2Of DNA,with
R1528 T1894 T1900 arg1Of Deficiencies,have
R15280 T20250 T20247 arg1Of DNA,the
R15281 T20250 T20248 arg1Of DNA,appropriate
R15282 T20250 T20249 arg1Of DNA,plasmid
R15283 T20250 T20251 arg1Of DNA,(
R15284 T20250 T20256 arg1Of DNA,using
R15285 T20254 T20251 arg2Of total,(
R15286 T20254 T20252 arg1Of total,~2
R15287 T20254 T20253 arg1Of total,μg
R15288 T20255 T20251 arg3Of ),(
R15289 T20256 T20261 arg1Of using,(
R1529 T1894 T1901 arg1Of Deficiencies,been
R15290 T20260 T20256 arg2Of reagent,using
R15291 T20260 T20257 arg1Of reagent,FuGene
R15292 T20260 T20258 arg1Of reagent,6
R15293 T20260 T20259 arg1Of reagent,transfection
R15294 T20262 T20263 arg1Of Roche,","
R15295 T20263 T20261 arg2Of ",",(
R15296 T20263 T20265 arg1Of ",",","
R15297 T20264 T20263 arg2Of Basel,","
R15298 T20266 T20265 arg2Of Switzerland,","
R15299 T20267 T20261 arg3Of ),(
R1530 T1894 T1902 arg2Of Deficiencies,linked
R15300 T20270 T20268 arg1Of cells,Jurkat
R15301 T20270 T20269 arg1Of cells,T
R15302 T20270 T20271 arg1Of cells,were
R15303 T20270 T20272 arg2Of cells,plated
R15304 T20270 T20296 arg1Of cells,using
R15305 T20272 T20271 arg2Of plated,were
R15306 T20272 T20273 arg1Of plated,at
R15307 T20272 T20283 arg1Of plated,day
R15308 T20272 T20296 modOf plated,using
R15309 T20277 T20273 arg2Of cells/well,at
R1531 T1897 T1898 arg1Of development,and
R15310 T20277 T20274 arg1Of cells/well,1
R15311 T20277 T20275 arg1Of cells/well,×
R15312 T20277 T20276 arg1Of cells/well,106
R15313 T20277 T20278 arg1Of cells/well,in
R15314 T20281 T20278 arg2Of plates,in
R15315 T20281 T20279 arg1Of plates,six-well
R15316 T20281 T20280 arg1Of plates,culture
R15317 T20283 T20282 arg1Of day,the
R15318 T20283 T20284 arg1Of day,of
R15319 T20283 T20286 arg1Of day,with
R1532 T1898 T1895 arg2Of and,in
R15320 T20285 T20284 arg2Of transfection,of
R15321 T20290 T20286 arg2Of DNA,with
R15322 T20290 T20287 arg1Of DNA,the
R15323 T20290 T20288 arg1Of DNA,appropriate
R15324 T20290 T20289 arg1Of DNA,plasmid
R15325 T20290 T20291 arg1Of DNA,(
R15326 T20294 T20291 arg2Of total,(
R15327 T20294 T20292 arg1Of total,~2
R15328 T20294 T20293 arg1Of total,μg
R15329 T20295 T20291 arg3Of ),(
R1533 T1898 T1896 arg1Of and,Treg
R15330 T20300 T20296 arg2Of reagent,using
R15331 T20300 T20297 arg1Of reagent,FuGene
R15332 T20300 T20298 arg1Of reagent,6
R15333 T20300 T20299 arg1Of reagent,transfection
R15334 T20305 T20301 arg1Of cells,Primary
R15335 T20305 T20302 arg1Of cells,human
R15336 T20305 T20303 arg1Of cells,CD4+
R15337 T20305 T20304 arg1Of cells,T
R15338 T20305 T20306 arg1Of cells,(
R15339 T20305 T20311 arg1Of cells,were
R1534 T1899 T1898 arg2Of function,and
R15340 T20305 T20312 arg2Of cells,nucleofected
R15341 T20305 T20323 arg1Of cells,using
R15342 T20307 T20308 arg1Of 2,×
R15343 T20308 T20306 arg2Of ×,(
R15344 T20309 T20308 arg2Of 106,×
R15345 T20310 T20306 arg3Of ),(
R15346 T20312 T20311 arg2Of nucleofected,were
R15347 T20312 T20313 arg1Of nucleofected,with
R15348 T20312 T20323 modOf nucleofected,using
R15349 T20317 T20313 arg2Of DNA,with
R1535 T1902 T1900 arg2Of linked,have
R15350 T20317 T20314 arg1Of DNA,the
R15351 T20317 T20315 arg2Of DNA,specified
R15352 T20317 T20316 arg1Of DNA,plasmid
R15353 T20317 T20318 arg1Of DNA,(
R15354 T20321 T20318 arg2Of total,(
R15355 T20321 T20319 arg1Of total,5
R15356 T20321 T20320 arg1Of total,μg
R15357 T20322 T20318 arg3Of ),(
R15358 T20323 T20330 arg1Of using,(
R15359 T20329 T20323 arg2Of Kit,using
R1536 T1902 T1901 arg2Of linked,been
R15360 T20329 T20324 arg1Of Kit,the
R15361 T20329 T20325 arg1Of Kit,Human
R15362 T20329 T20326 arg1Of Kit,T
R15363 T20329 T20327 arg1Of Kit,Cell
R15364 T20329 T20328 arg1Of Kit,Nucleofection
R15365 T20331 T20332 arg1Of Amaxa,","
R15366 T20332 T20334 arg1Of ",",","
R15367 T20333 T20332 arg2Of Gaithersburg,","
R15368 T20334 T20336 arg1Of ",",","
R15369 T20335 T20334 arg2Of Maryland,","
R1537 T1902 T1903 arg1Of linked,to
R15370 T20337 T20336 arg2Of United,","
R15371 T20338 T20330 arg2Of States,(
R15372 T20338 T20331 arg1Of States,Amaxa
R15373 T20338 T20333 arg1Of States,Gaithersburg
R15374 T20338 T20335 arg1Of States,Maryland
R15375 T20338 T20337 arg1Of States,United
R15376 T20339 T20330 arg3Of ),(
R15377 T20340 T20341 arg1Of Forskolin,(
R15378 T20340 T20355 arg1Of Forskolin,was
R15379 T20340 T20356 arg2Of Forskolin,added
R1538 T1906 T1905 arg1Of autoimmune,severe
R15380 T20343 T20341 arg2Of μM,(
R15381 T20343 T20342 arg1Of μM,10
R15382 T20343 T20344 arg1Of μM,;
R15383 T20343 T20351 arg1Of μM,","
R15384 T20345 T20346 arg1Of Calbiochem,","
R15385 T20345 T20349 arg1Of Calbiochem,","
R15386 T20348 T20346 arg2Of Diego,","
R15387 T20348 T20347 arg1Of Diego,San
R15388 T20349 T20344 arg2Of ",",;
R15389 T20350 T20349 arg2Of California,","
R1539 T1907 T1903 arg2Of disorder,to
R15390 T20353 T20351 arg2Of States,","
R15391 T20353 T20352 arg1Of States,United
R15392 T20354 T20341 arg3Of ),(
R15393 T20356 T20355 arg2Of added,was
R15394 T20356 T20357 arg1Of added,in
R15395 T20362 T20357 arg2Of posttransfection,in
R15396 T20362 T20358 arg1Of posttransfection,some
R15397 T20362 T20359 arg1Of posttransfection,experiments
R15398 T20362 T20360 arg1Of posttransfection,20
R15399 T20362 T20361 arg1Of posttransfection,h
R1540 T1907 T1904 arg1Of disorder,the
R15400 T20363 T20364 arg1Of Cells,were
R15401 T20363 T20365 arg2Of Cells,harvested
R15402 T20365 T20364 arg2Of harvested,were
R15403 T20365 T20369 arg1Of harvested,and
R15404 T20368 T20365 arg3Of posttransfection,harvested
R15405 T20368 T20366 arg1Of posttransfection,24
R15406 T20368 T20367 arg1Of posttransfection,h
R15407 T20369 T20383 arg1Of and,and
R15408 T20371 T20370 arg1Of activity,luciferase
R15409 T20371 T20372 arg1Of activity,was
R1541 T1907 T1906 arg1Of disorder,autoimmune
R15410 T20371 T20373 arg2Of activity,analyzed
R15411 T20373 T20369 arg2Of analyzed,and
R15412 T20373 T20372 arg2Of analyzed,was
R15413 T20374 T20373 arg3Of using,analyzed
R15414 T20379 T20374 arg2Of System,using
R15415 T20379 T20375 arg1Of System,the
R15416 T20379 T20376 arg1Of System,Dual-luciferase
R15417 T20379 T20377 arg1Of System,Reporter
R15418 T20379 T20378 arg1Of System,Assay
R15419 T20379 T20380 arg1Of System,(
R1542 T1907 T1908 arg2Of disorder,known
R15420 T20381 T20380 arg2Of Promega,(
R15421 T20382 T20380 arg3Of ),(
R15422 T20385 T20386 arg1Of Monolight,2010
R15423 T20387 T20384 arg1Of luminometer,a
R15424 T20387 T20385 arg1Of luminometer,Monolight
R15425 T20387 T20388 arg1Of luminometer,(
R15426 T20387 T20407 arg1Of luminometer,was
R15427 T20387 T20408 arg2Of luminometer,used
R15428 T20387 T20414 arg1Of luminometer,normalize
R15429 T20391 T20389 arg1Of Laboratory,Analytical
R1543 T1908 T1909 arg1Of known,as
R15430 T20391 T20390 arg1Of Laboratory,Luminescence
R15431 T20391 T20392 arg1Of Laboratory,","
R15432 T20392 T20395 arg1Of ",",","
R15433 T20394 T20392 arg2Of Diego,","
R15434 T20394 T20393 arg1Of Diego,San
R15435 T20395 T20397 arg1Of ",",","
R15436 T20396 T20395 arg2Of California,","
R15437 T20397 T20388 arg2Of ",",(
R15438 T20399 T20397 arg2Of States,","
R15439 T20399 T20398 arg1Of States,United
R1544 T1908 T1922 arg1Of known,[
R15440 T20400 T20388 arg3Of ),(
R15441 T20402 T20401 arg2Of to,according
R15442 T20403 T20404 arg2Of manufacturer,'s
R15443 T20406 T20402 arg2Of pGL4-TKhRluc2,to
R15444 T20406 T20404 arg1Of pGL4-TKhRluc2,'s
R15445 T20406 T20405 arg1Of pGL4-TKhRluc2,guidelines.
R15446 T20408 T20383 arg2Of used,and
R15447 T20408 T20401 arg1Of used,according
R15448 T20408 T20407 arg2Of used,was
R15449 T20408 T20409 arg1Of used,as
R1545 T1911 T1910 arg1Of dysregulation,immune
R15450 T20408 T20413 modOf used,to
R15451 T20412 T20409 arg2Of control,as
R15452 T20412 T20410 arg1Of control,an
R15453 T20412 T20411 arg1Of control,internal
R15454 T20414 T20413 arg1Of normalize,to
R15455 T20414 T20415 arg1Of normalize,for
R15456 T20417 T20415 arg2Of efficiency,for
R15457 T20417 T20416 arg1Of efficiency,transfection
R15458 T20421 T20418 arg2Of cells,Nucleofected
R15459 T20421 T20419 arg1Of cells,CD4+
R1546 T1911 T1912 arg1Of dysregulation,","
R15460 T20421 T20420 arg1Of cells,T
R15461 T20421 T20422 arg1Of cells,were
R15462 T20421 T20424 arg2Of cells,monitored
R15463 T20424 T20422 arg2Of monitored,were
R15464 T20424 T20423 arg1Of monitored,also
R15465 T20424 T20425 arg1Of monitored,for
R15466 T20427 T20426 arg1Of efficiency,transfection
R15467 T20427 T20428 arg1Of efficiency,and
R15468 T20428 T20425 arg2Of and,for
R15469 T20428 T20434 arg1Of and,as
R1547 T1912 T1914 arg1Of ",",","
R15470 T20433 T20428 arg2Of posttransfection,and
R15471 T20433 T20429 arg1Of posttransfection,cell
R15472 T20433 T20430 arg1Of posttransfection,viability
R15473 T20433 T20431 arg1Of posttransfection,24
R15474 T20433 T20432 arg1Of posttransfection,h
R15475 T20435 T20434 arg2Of follows,as
R15476 T20437 T20436 arg1Of efficiency,Transfection
R15477 T20437 T20438 arg1Of efficiency,was
R15478 T20438 T20442 arg1Of was,as
R15479 T20440 T20439 arg1Of ~30,routinely
R1548 T1913 T1912 arg2Of polyendocrinopathy,","
R15480 T20441 T20438 arg2Of %,was
R15481 T20441 T20440 arg1Of %,~30
R15482 T20443 T20442 arg2Of determined,as
R15483 T20447 T20443 arg1Of analysis,determined
R15484 T20447 T20444 arg2Of analysis,by
R15485 T20447 T20445 arg1Of analysis,flow
R15486 T20447 T20446 arg1Of analysis,cytometric
R15487 T20447 T20448 arg1Of analysis,of
R15488 T20450 T20448 arg2Of expression,of
R15489 T20450 T20449 arg1Of expression,EGFP
R1549 T1914 T1916 arg1Of ",",","
R15490 T20452 T20451 arg1Of viability,Cell
R15491 T20452 T20453 arg1Of viability,","
R15492 T20452 T20454 arg2Of viability,determined
R15493 T20452 T20467 arg1Of viability,was
R15494 T20454 T20455 arg1Of determined,by
R15495 T20456 T20455 arg2Of staining,by
R15496 T20456 T20457 arg1Of staining,with
R15497 T20459 T20457 arg2Of D,with
R15498 T20459 T20458 arg1Of D,7-amino-actinomycin
R15499 T20459 T20460 arg1Of D,(
R1550 T1915 T1914 arg2Of enteropathy,","
R15500 T20461 T20460 arg2Of 7-AAD,(
R15501 T20461 T20462 arg1Of 7-AAD,;
R15502 T20464 T20462 arg2Of Biosciences,;
R15503 T20464 T20463 arg1Of Biosciences,BD
R15504 T20465 T20460 arg3Of ),(
R15505 T20467 T20466 arg1Of was,","
R15506 T20469 T20468 arg1Of ~70,routinely
R15507 T20470 T20467 arg2Of %,was
R15508 T20470 T20469 arg1Of %,~70
R15509 T20473 T20472 arg1Of efficiency,transfection
R1551 T1916 T1909 arg2Of ",",as
R15510 T20473 T20474 arg1Of efficiency,and
R15511 T20474 T20471 arg1Of and,Both
R15512 T20474 T20477 arg1Of and,in
R15513 T20474 T20482 arg1Of and,was
R15514 T20474 T20483 arg1Of and,independent
R15515 T20476 T20474 arg2Of viability,and
R15516 T20476 T20475 arg1Of viability,cell
R15517 T20481 T20477 arg2Of cells,in
R15518 T20481 T20478 arg2Of cells,nucleofected
R15519 T20481 T20479 arg1Of cells,CD4+
R1552 T1918 T1916 arg2Of syndrome,","
R15520 T20481 T20480 arg1Of cells,T
R15521 T20483 T20482 arg2Of independent,was
R15522 T20483 T20484 arg1Of independent,of
R15523 T20486 T20484 arg2Of plasmids,of
R15524 T20486 T20485 arg1Of plasmids,the
R15525 T20486 T20487 arg2Of plasmids,used
R1553 T1918 T1917 arg1Of syndrome,X-linked
R1554 T1918 T1919 arg1Of syndrome,(
R1555 T1920 T1919 arg2Of IPEX,(
R1556 T1921 T1919 arg3Of ),(
R1557 T1923 T1922 arg2Of 4,[
R1558 T1924 T1922 arg3Of ],[
R1559 T1926 T1925 arg2Of addition,In
R1560 T1929 T1928 arg1Of studies,recent
R1561 T1929 T1930 arg1Of studies,have
R1562 T1929 T1931 arg1Of studies,provided
R1563 T1931 T1925 arg1Of provided,In
R1564 T1931 T1927 arg1Of provided,","
R1565 T1931 T1930 arg2Of provided,have
R1566 T1933 T1931 arg2Of evidence,provided
R1567 T1933 T1932 arg1Of evidence,strong
R1568 T1935 T1936 arg1Of dysregulation,of
R1569 T1935 T1941 arg1Of dysregulation,may
R1570 T1935 T1942 arg1Of dysregulation,be
R1571 T1938 T1937 arg1Of development,Treg
R1572 T1938 T1939 arg1Of development,and/or
R15725 T20807 T20808 arg1Of Foxp3,and
R15726 T20808 T20813 arg1Of and,by
R15727 T20812 T20808 arg2Of analysis,and
R15728 T20812 T20809 arg1Of analysis,HTLV-I
R15729 T20812 T20810 arg1Of analysis,Tax
R1573 T1939 T1936 arg2Of and/or,of
R15730 T20812 T20811 arg1Of analysis,expression
R15731 T20815 T20813 arg2Of RT-PCR,by
R15732 T20815 T20814 arg1Of RT-PCR,real-time
R15733 T20818 T20816 arg1Of analysis,Real-time
R15734 T20818 T20817 arg1Of analysis,RT-PCR
R15735 T20818 T20819 arg1Of analysis,of
R15736 T20818 T20825 arg1Of analysis,was
R15737 T20818 T20826 arg2Of analysis,performed
R15738 T20820 T20821 arg1Of Foxp3,and
R15739 T20822 T20821 arg2Of HTLV-I,and
R1574 T1940 T1939 arg2Of function,and/or
R15740 T20824 T20819 arg2Of expression,of
R15741 T20824 T20820 arg1Of expression,Foxp3
R15742 T20824 T20822 arg1Of expression,HTLV-I
R15743 T20824 T20823 arg1Of expression,Tax
R15744 T20826 T20825 arg2Of performed,was
R15745 T20826 T20827 arg1Of performed,as
R15746 T20829 T20828 arg1Of described,previously
R15747 T20831 T20827 arg2Of "8,47",as
R15748 T20831 T20829 arg1Of "8,47",described
R15749 T20831 T20830 arg2Of "8,47",[
R1575 T1942 T1933 arg2Of be,evidence
R15750 T20832 T20830 arg3Of ],[
R15751 T20836 T20835 arg1Of RNA,total
R15752 T20836 T20837 arg1Of RNA,was
R15753 T20836 T20838 arg2Of RNA,extracted
R15754 T20838 T20837 arg2Of extracted,was
R15755 T20838 T20839 modOf extracted,using
R15756 T20838 T20860 arg1Of extracted,and
R15757 T20839 T20854 arg1Of using,according
R15758 T20843 T20839 arg2Of Kit,using
R15759 T20843 T20840 arg1Of Kit,the
R1576 T1942 T1934 arg1Of be,that
R15760 T20843 T20841 arg1Of Kit,RNeasy
R15761 T20843 T20842 arg1Of Kit,Mini
R15762 T20843 T20844 arg1Of Kit,(
R15763 T20845 T20846 arg1Of Qiagen,","
R15764 T20846 T20848 arg1Of ",",","
R15765 T20847 T20846 arg2Of Valencia,","
R15766 T20848 T20850 arg1Of ",",","
R15767 T20849 T20848 arg2Of California,","
R15768 T20851 T20850 arg2Of United,","
R15769 T20852 T20844 arg2Of States,(
R1577 T1942 T1941 arg2Of be,may
R15770 T20852 T20845 arg1Of States,Qiagen
R15771 T20852 T20847 arg1Of States,Valencia
R15772 T20852 T20849 arg1Of States,California
R15773 T20852 T20851 arg1Of States,United
R15774 T20853 T20844 arg3Of ),(
R15775 T20855 T20854 arg2Of to,according
R15776 T20856 T20857 arg2Of manufacturer,'s
R15777 T20858 T20855 arg2Of guidelines,to
R15778 T20858 T20857 arg1Of guidelines,'s
R15779 T20860 T20833 arg1Of and,Briefly
R1578 T1945 T1942 arg2Of factor,be
R15780 T20860 T20834 arg1Of and,","
R15781 T20860 T20859 arg1Of and,","
R15782 T20861 T20862 arg1Of cDNA,was
R15783 T20861 T20863 arg2Of cDNA,synthesized
R15784 T20863 T20860 arg2Of synthesized,and
R15785 T20863 T20862 arg2Of synthesized,was
R15786 T20866 T20863 arg1Of transcription,synthesized
R15787 T20866 T20864 arg2Of transcription,by
R15788 T20866 T20865 arg1Of transcription,reverse
R15789 T20866 T20867 arg1Of transcription,using
R1579 T1945 T1943 arg1Of factor,a
R15790 T20869 T20868 arg1Of Gold,TaqMan
R15791 T20871 T20867 arg2Of Kit,using
R15792 T20871 T20869 arg1Of Kit,Gold
R15793 T20871 T20870 arg1Of Kit,RT-PCR
R15794 T20871 T20872 arg1Of Kit,using
R15795 T20875 T20872 arg2Of primers,using
R15796 T20875 T20873 arg1Of primers,random
R15797 T20875 T20874 arg1Of primers,hexamer
R15798 T20875 T20876 arg1Of primers,(
R15799 T20878 T20877 arg1Of Biosystems,Applied
R1580 T1945 T1944 arg1Of factor,significant
R15800 T20878 T20879 arg1Of Biosystems,","
R15801 T20879 T20882 arg1Of ",",","
R15802 T20881 T20879 arg2Of City,","
R15803 T20881 T20880 arg1Of City,Foster
R15804 T20882 T20884 arg1Of ",",","
R15805 T20883 T20882 arg2Of California,","
R15806 T20884 T20876 arg2Of ",",(
R15807 T20886 T20884 arg2Of States,","
R15808 T20886 T20885 arg1Of States,United
R15809 T20887 T20876 arg3Of ),(
R1581 T1945 T1946 arg1Of factor,in
R15810 T20888 T20889 arg1Of Foxp3,and
R15811 T20890 T20889 arg2Of HTLV-I,and
R15812 T20893 T20888 arg1Of expression,Foxp3
R15813 T20893 T20890 arg1Of expression,HTLV-I
R15814 T20893 T20891 arg1Of expression,Tax
R15815 T20893 T20892 arg1Of expression,mRNA
R15816 T20893 T20894 arg1Of expression,was
R15817 T20893 T20895 arg2Of expression,quantified
R15818 T20895 T20894 arg2Of quantified,was
R15819 T20898 T20895 arg1Of PCR,quantified
R1582 T1948 T1946 arg2Of pathogenesis,in
R15820 T20898 T20896 arg2Of PCR,by
R15821 T20898 T20897 arg1Of PCR,real-time
R15822 T20898 T20899 arg1Of PCR,using
R15823 T20903 T20900 arg1Of Sequence,ABI
R15824 T20903 T20901 arg1Of Sequence,PRISM
R15825 T20903 T20902 arg1Of Sequence,7700
R15826 T20905 T20899 arg2Of System,using
R15827 T20905 T20903 arg1Of System,Sequence
R15828 T20905 T20904 arg1Of System,Detection
R15829 T20905 T20906 arg1Of System,(
R1583 T1948 T1947 arg1Of pathogenesis,the
R15830 T20908 T20906 arg2Of Biosystems,(
R15831 T20908 T20907 arg1Of Biosystems,Applied
R15832 T20909 T20906 arg3Of ),(
R15833 T20912 T20910 arg1Of values,The
R15834 T20912 T20911 arg1Of values,normalized
R15835 T20912 T20913 arg1Of values,in
R15836 T20912 T20916 arg1Of values,were
R15837 T20912 T20917 arg2Of values,calculated
R15838 T20915 T20913 arg2Of sample,in
R15839 T20915 T20914 arg1Of sample,each
R1584 T1948 T1949 arg1Of pathogenesis,of
R15840 T20917 T20916 arg2Of calculated,were
R15841 T20917 T20918 arg1Of calculated,as
R15842 T20921 T20918 arg2Of quantity,as
R15843 T20921 T20919 arg1Of quantity,the
R15844 T20921 T20920 arg1Of quantity,relative
R15845 T20921 T20922 arg1Of quantity,of
R15846 T20923 T20924 arg1Of Foxp3,or
R15847 T20925 T20924 arg2Of HTLV-I,or
R15848 T20928 T20922 arg2Of expression,of
R15849 T20928 T20923 arg1Of expression,Foxp3
R1585 T1952 T1950 arg1Of disorders,several
R15850 T20928 T20925 arg1Of expression,HTLV-I
R15851 T20928 T20926 arg1Of expression,Tax
R15852 T20928 T20927 arg1Of expression,mRNA
R15853 T20928 T20929 arg2Of expression,divided
R15854 T20933 T20929 arg1Of quantity,divided
R15855 T20933 T20930 arg2Of quantity,by
R15856 T20933 T20931 arg1Of quantity,the
R15857 T20933 T20932 arg1Of quantity,relative
R15858 T20933 T20934 arg1Of quantity,of
R15859 T20937 T20934 arg2Of expression,of
R1586 T1952 T1951 arg1Of disorders,autoimmune
R15860 T20937 T20935 arg1Of expression,HPRT
R15861 T20937 T20936 arg1Of expression,mRNA
R15862 T20939 T20938 arg1Of values,The
R15863 T20939 T20940 arg1Of values,were
R15864 T20939 T20941 arg2Of values,calculated
R15865 T20941 T20940 arg2Of calculated,were
R15866 T20945 T20943 arg1Of formula,the
R15867 T20945 T20944 arg1Of formula,following
R15868 T20945 T20946 arg1Of formula,:
R15869 T20948 T20947 arg2Of Foxp3,normalized
R1587 T1952 T1953 arg1Of disorders,(
R15870 T20948 T20949 arg1Of Foxp3,or
R15871 T20949 T20946 arg2Of or,:
R15872 T20952 T20949 arg2Of expression,or
R15873 T20952 T20950 arg1Of expression,HTLV-I
R15874 T20952 T20951 arg1Of expression,Tax
R15875 T20955 T20941 arg1Of value,calculated
R15876 T20955 T20942 arg2Of value,by
R15877 T20955 T20945 arg1Of value,formula
R15878 T20955 T20953 arg1Of value,=
R15879 T20955 T20954 arg1Of value,2Ct
R1588 T1952 T1976 arg1Of disorders,and
R15880 T20955 T20956 arg1Of value,of
R15881 T20957 T20958 arg1Of HPRT,–
R15882 T20959 T20958 arg2Of Ct,–
R15883 T20960 T20956 arg2Of value,of
R15884 T20960 T20957 arg1Of value,HPRT
R15885 T20960 T20959 arg1Of value,Ct
R15886 T20960 T20961 arg1Of value,of
R15887 T20962 T20963 arg1Of Foxp3,or
R15888 T20963 T20961 arg2Of or,of
R15889 T20965 T20963 arg2Of Tax,or
R1589 T1957 T1954 arg1Of sclerosis,e.g.
R15890 T20965 T20964 arg1Of Tax,HTLV-I
R1590 T2018 T2011 arg2Of protein,is
R1591 T2018 T2012 arg1Of protein,a
R1592 T2018 T2013 arg1Of protein,431-amino
R1593 T2018 T2014 arg1Of protein,acid
R1594 T2018 T2015 arg1Of protein,(
R1595 T2018 T2016 arg1Of protein,48-kDa
R1596 T2018 T2017 arg1Of protein,)
R1597 T2018 T2019 arg2Of protein,expressed
R1598 T2019 T2020 arg1Of expressed,at
R1599 T2019 T2024 arg1Of expressed,in
R1600 T2022 T2021 arg1Of high,very
R1601 T1957 T1955 arg1Of sclerosis,","
R1602 T2023 T2020 arg2Of levels,at
R1603 T2023 T2022 arg1Of levels,high
R1604 T1957 T1956 arg1Of sclerosis,multiple
R1605 T1957 T1958 arg1Of sclerosis,[
R1606 T1957 T1961 arg1Of sclerosis,","
R16068 T21269 T21268 arg1Of PCR,Real-time
R16069 T21272 T21270 arg1Of analysis,Real-time
R1607 T2027 T2024 arg2Of cells,in
R16070 T21272 T21271 arg1Of analysis,PCR
R16071 T21272 T21273 arg1Of analysis,of
R16072 T21272 T21280 arg1Of analysis,was
R16073 T21272 T21281 arg2Of analysis,performed
R16074 T21276 T21275 arg2Of Tax,(
R16075 T21277 T21275 arg3Of ),(
R16076 T21279 T21273 arg2Of load,of
R16077 T21279 T21274 arg1Of load,HTLV-I
R16078 T21279 T21275 arg1Of load,(
R16079 T21279 T21278 arg1Of load,proviral
R1608 T2027 T2025 arg1Of cells,CD4+CD25hi
R16080 T21281 T21280 arg2Of performed,was
R16081 T21281 T21282 arg1Of performed,as
R16082 T21284 T21283 arg1Of described,previously
R16083 T21286 T21282 arg2Of "47,50",as
R16084 T21286 T21284 arg1Of "47,50",described
R16085 T21286 T21285 arg2Of "47,50",[
R16086 T21287 T21285 arg3Of ],[
R16087 T21288 T21289 arg1Of DNA,was
R16088 T21288 T21290 arg2Of DNA,extracted
R16089 T21290 T21289 arg2Of extracted,was
R1609 T2027 T2026 arg1Of cells,T
R16090 T21290 T21291 arg1Of extracted,from
R16091 T21290 T21296 modOf extracted,using
R16092 T21290 T21312 arg1Of extracted,and
R16093 T21295 T21291 arg2Of cells,from
R16094 T21295 T21292 arg1Of cells,1
R16095 T21295 T21293 arg1Of cells,×
R16096 T21295 T21294 arg1Of cells,106
R16097 T21296 T21301 arg1Of using,(
R16098 T21300 T21296 arg2Of Kit,using
R16099 T21300 T21297 arg1Of Kit,Puregene
R1610 T1959 T1958 arg2Of 5,[
R16100 T21300 T21298 arg1Of Kit,DNA
R16101 T21300 T21299 arg1Of Kit,Isolation
R16102 T21302 T21303 arg1Of Gentra,","
R16103 T21303 T21305 arg1Of ",",","
R16104 T21304 T21303 arg2Of Minneapolis,","
R16105 T21305 T21307 arg1Of ",",","
R16106 T21306 T21305 arg2Of Minnesota,","
R16107 T21308 T21307 arg2Of United,","
R16108 T21309 T21301 arg2Of States,(
R16109 T21309 T21302 arg1Of States,Gentra
R1611 T2032 T2028 arg2Of shown,and
R16110 T21309 T21304 arg1Of States,Minneapolis
R16111 T21309 T21306 arg1Of States,Minnesota
R16112 T21309 T21308 arg1Of States,United
R16113 T21310 T21301 arg3Of ),(
R16114 T21312 T21311 arg1Of and,","
R16115 T21314 T21313 arg1Of ng,100
R16116 T21314 T21315 arg1Of ng,of
R16117 T21314 T21320 arg1Of ng,was
R16118 T21314 T21321 arg2Of ng,analyzed
R16119 T21319 T21315 arg2Of solution,of
R1612 T2032 T2029 arg2Of shown,has
R16120 T21319 T21316 arg1Of solution,the
R16121 T21319 T21317 arg1Of solution,sample
R16122 T21319 T21318 arg1Of solution,DNA
R16123 T21321 T21312 arg2Of analyzed,and
R16124 T21321 T21320 arg2Of analyzed,was
R16125 T21324 T21321 arg1Of system,analyzed
R16126 T21324 T21322 arg2Of system,by
R16127 T21324 T21323 arg1Of system,this
R16128 T21329 T21325 arg1Of load,The
R16129 T21329 T21326 arg1Of load,HTLV-I
R1613 T2032 T2030 arg1Of shown,previously
R16130 T21329 T21327 arg1Of load,proviral
R16131 T21329 T21328 arg1Of load,DNA
R16132 T21329 T21330 arg1Of load,was
R16133 T21329 T21331 arg2Of load,calculated
R16134 T21331 T21330 arg2Of calculated,was
R16135 T21331 T21336 arg1Of calculated,:
R16136 T21335 T21331 arg1Of formula,calculated
R16137 T21335 T21332 arg2Of formula,by
R16138 T21335 T21333 arg1Of formula,the
R16139 T21335 T21334 arg1Of formula,following
R1614 T2032 T2031 arg2Of shown,been
R16140 T21338 T21337 arg1Of number,copy
R16141 T21338 T21339 arg1Of number,of
R16142 T21338 T21344 arg1Of number,per
R16143 T21338 T21354 arg1Of number,/
R16144 T21338 T21361 arg1Of number,×
R16145 T21340 T21339 arg2Of HTLV-I,of
R16146 T21340 T21341 arg1Of HTLV-I,(
R16147 T21342 T21341 arg2Of pX,(
R16148 T21343 T21341 arg3Of ),(
R16149 T21346 T21344 arg2Of cells,per
R1615 T1960 T1958 arg3Of ],[
R16150 T21346 T21345 arg1Of cells,100
R16151 T21346 T21347 arg1Of cells,=
R16152 T21346 T21348 arg1Of cells,(
R16153 T21350 T21348 arg2Of number,(
R16154 T21350 T21349 arg1Of number,copy
R16155 T21350 T21351 arg1Of number,of
R16156 T21352 T21351 arg2Of pX,of
R16157 T21353 T21348 arg3Of ),(
R16158 T21354 T21355 arg1Of /,(
R16159 T21357 T21355 arg2Of number,(
R1616 T2034 T2032 arg3Of be,shown
R16160 T21357 T21356 arg1Of number,copy
R16161 T21357 T21358 arg1Of number,of
R16162 T21359 T21358 arg2Of β-actin/2,of
R16163 T21360 T21355 arg3Of ),(
R16164 T21361 T21336 arg2Of ×,:
R16165 T21362 T21361 arg2Of 100,×
R1617 T2034 T2033 arg1Of be,to
R1618 T2036 T2034 arg2Of critical,be
R1619 T2036 T2035 arg1Of critical,absolutely
R1620 T2036 T2037 arg1Of critical,for
R1621 T1961 T1968 arg1Of ",",and
R1622 T2039 T2038 arg1Of development,Treg
R1623 T2039 T2040 arg1Of development,and
R1624 T1963 T1961 arg2Of gravis,","
R1625 T2040 T2037 arg2Of and,for
R1626 T2041 T2040 arg2Of function,and
R1627 T2041 T2042 arg1Of function,[
R1628 T2043 T2042 arg2Of 11–14,[
R1629 T1963 T1962 arg1Of gravis,myasthenia
R1630 T2044 T2042 arg3Of ],[
R1631 T1963 T1964 arg1Of gravis,[
R1632 T2045 T2046 arg1Of Foxp3,contains
R1633 T1965 T1964 arg2Of 6,[
R1634 T1966 T1964 arg3Of ],[
R1635 T2050 T2046 arg2Of domain,contains
R1636 T2050 T2047 arg1Of domain,a
R1637 T2050 T2048 arg1Of domain,proline-rich
R1638 T2050 T2049 arg1Of domain,amino-terminal
R1639 T2050 T2051 arg2Of domain,reported
R1640 T2050 T2053 arg1Of domain,function
R1641 T2053 T2051 arg3Of function,reported
R1642 T2053 T2052 arg1Of function,to
R1643 T2053 T2054 arg1Of function,as
R1644 T1968 T1953 arg2Of and,(
R1645 T2061 T2055 arg1Of cells,a
R1646 T2061 T2056 arg1Of cells,nuclear
R1647 T2061 T2057 arg1Of cells,factor
R1648 T2061 T2058 arg1Of cells,of
R1649 T2061 T2059 arg2Of cells,activated
R1650 T2061 T2060 arg1Of cells,T
R1651 T2061 T2062 arg1Of cells,(
R1652 T2061 T2065 arg1Of cells,and
R1653 T2063 T2062 arg2Of NF-AT,(
R16533 T21785 T21783 arg1Of analysis,Western
R16534 T21785 T21784 arg1Of analysis,blot
R16535 T21788 T21786 arg1Of cells,HEK
R16536 T21788 T21787 arg1Of cells,293T
R16537 T21788 T21789 arg1Of cells,were
R16538 T21788 T21790 arg2Of cells,plated
R16539 T21788 T21822 arg1Of cells,using
R1654 T2064 T2062 arg3Of ),(
R16540 T21790 T21789 arg2Of plated,were
R16541 T21790 T21791 arg1Of plated,at
R16542 T21790 T21822 modOf plated,using
R16543 T21793 T21791 arg2Of density,at
R16544 T21793 T21792 arg1Of density,a
R16545 T21793 T21794 arg1Of density,of
R16546 T21793 T21799 arg1Of density,in
R16547 T21797 T21796 arg1Of 105,×
R16548 T21798 T21794 arg2Of cells/well,of
R16549 T21798 T21795 arg1Of cells/well,5
R1655 T1968 T1967 arg1Of and,","
R16550 T21798 T21797 arg1Of cells/well,105
R16551 T21802 T21799 arg2Of plates,in
R16552 T21802 T21800 arg1Of plates,six-well
R16553 T21802 T21801 arg1Of plates,culture
R16554 T21802 T21803 arg1Of plates,(
R16555 T21805 T21803 arg2Of Biosciences,(
R16556 T21805 T21804 arg1Of Biosciences,BD
R16557 T21806 T21803 arg3Of ),(
R16558 T21808 T21791 arg3Of d,at
R16559 T21808 T21807 arg1Of d,1
R1656 T1971 T1968 arg2Of diabetes,and
R16560 T21808 T21809 arg1Of d,prior
R16561 T21808 T21812 arg1Of d,with
R16562 T21809 T21810 arg1Of prior,to
R16563 T21811 T21810 arg2Of transfection,to
R16564 T21816 T21812 arg2Of DNA,with
R16565 T21816 T21813 arg1Of DNA,the
R16566 T21816 T21814 arg1Of DNA,appropriate
R16567 T21816 T21815 arg1Of DNA,plasmid
R16568 T21816 T21817 arg1Of DNA,(
R16569 T21820 T21817 arg2Of total,(
R1657 T2065 T2090 arg1Of and,and
R16570 T21820 T21818 arg1Of total,2
R16571 T21820 T21819 arg1Of total,μg
R16572 T21821 T21817 arg3Of ),(
R16573 T21826 T21822 arg2Of reagent,using
R16574 T21826 T21823 arg1Of reagent,FuGene
R16575 T21826 T21824 arg1Of reagent,6
R16576 T21826 T21825 arg1Of reagent,transfection
R16577 T21826 T21827 arg1Of reagent,(
R16578 T21828 T21827 arg2Of Roche,(
R16579 T21829 T21827 arg3Of ),(
R1658 T1971 T1969 arg1Of diabetes,type
R16580 T21830 T21831 arg1Of Cells,were
R16581 T21830 T21832 arg2Of Cells,harvested
R16582 T21832 T21831 arg2Of harvested,were
R16583 T21835 T21832 arg3Of posttransfection,harvested
R16584 T21835 T21833 arg1Of posttransfection,24
R16585 T21835 T21834 arg1Of posttransfection,h
R16586 T21835 T21836 arg1Of posttransfection,for
R16587 T21835 T21839 arg1Of posttransfection,in
R16588 T21835 T21842 arg1Of posttransfection,(
R16589 T21838 T21836 arg2Of lysates,for
R1659 T1971 T1970 arg1Of diabetes,1
R16590 T21838 T21837 arg1Of lysates,whole-cell
R16591 T21841 T21839 arg2Of buffer,in
R16592 T21841 T21840 arg1Of buffer,RIPA
R16593 T21843 T21844 arg1Of 50,mM
R16594 T21845 T21843 arg1Of Tris-HCl,50
R16595 T21845 T21846 arg1Of Tris-HCl,[
R16596 T21845 T21850 arg1Of Tris-HCl,","
R16597 T21847 T21846 arg2Of pH,[
R16598 T21847 T21848 arg1Of pH,7.4
R16599 T21849 T21846 arg3Of ],[
R1660 T2067 T2066 arg1Of factor-κB,nuclear
R16600 T21850 T21854 arg1Of ",",","
R16601 T21851 T21852 arg1Of 150,mM
R16602 T21853 T21850 arg2Of NaCl,","
R16603 T21853 T21851 arg1Of NaCl,150
R16604 T21854 T21861 arg1Of ",",","
R16605 T21855 T21856 arg1Of 1,%
R16606 T21857 T21854 arg2Of Igepal,","
R16607 T21857 T21855 arg1Of Igepal,1
R16608 T21857 T21858 arg1Of Igepal,(
R16609 T21859 T21858 arg2Of NP-40,(
R1661 T2067 T2068 arg1Of factor-κB,(
R16610 T21860 T21858 arg3Of ),(
R16611 T21861 T21842 arg2Of ",",(
R16612 T21861 T21866 arg1Of ",",","
R16613 T21862 T21863 arg1Of 0.5,%
R16614 T21865 T21861 arg2Of deoxycholate,","
R16615 T21865 T21862 arg1Of deoxycholate,0.5
R16616 T21865 T21864 arg1Of deoxycholate,sodium
R16617 T21867 T21868 arg1Of 1,mM
R16618 T21869 T21867 arg1Of EDTA,1
R16619 T21869 T21870 arg1Of EDTA,","
R1662 T1971 T1972 arg1Of diabetes,[
R16620 T21870 T21874 arg1Of ",",","
R16621 T21871 T21872 arg1Of 1,mM
R16622 T21873 T21870 arg2Of DTT,","
R16623 T21873 T21871 arg1Of DTT,1
R16624 T21874 T21879 arg1Of ",",and
R16625 T21875 T21876 arg1Of 1,mM
R16626 T21877 T21874 arg2Of PMSF,","
R16627 T21877 T21875 arg1Of PMSF,1
R16628 T21879 T21866 arg2Of and,","
R16629 T21879 T21878 arg1Of and,","
R1663 T2069 T2068 arg2Of NF-κB,(
R16630 T21884 T21879 arg2Of Inhibitor,and
R16631 T21884 T21880 arg1Of Inhibitor,1×
R16632 T21884 T21881 arg1Of Inhibitor,Complete
R16633 T21884 T21882 arg1Of Inhibitor,Mini
R16634 T21884 T21883 arg1Of Inhibitor,Protease
R16635 T21884 T21885 arg1Of Inhibitor,[
R16636 T21886 T21885 arg2Of Roche,[
R16637 T21887 T21885 arg3Of ],[
R16638 T21888 T21842 arg3Of ),(
R16639 T21890 T21889 arg1Of concentration,Protein
R1664 T1973 T1972 arg2Of 7,[
R16640 T21890 T21891 arg1Of concentration,was
R16641 T21890 T21892 arg2Of concentration,determined
R16642 T21892 T21891 arg2Of determined,was
R16643 T21892 T21896 arg1Of determined,(
R16644 T21892 T21906 arg1Of determined,and
R16645 T21895 T21892 arg1Of assay,determined
R16646 T21895 T21893 arg2Of assay,by
R16647 T21895 T21894 arg1Of assay,Lowry
R16648 T21897 T21898 arg1Of Bio-Rad,","
R16649 T21898 T21900 arg1Of ",",","
R1665 T2070 T2068 arg3Of ),(
R16650 T21899 T21898 arg2Of Hercules,","
R16651 T21900 T21902 arg1Of ",",","
R16652 T21901 T21900 arg2Of California,","
R16653 T21902 T21896 arg2Of ",",(
R16654 T21904 T21902 arg2Of States,","
R16655 T21904 T21903 arg1Of States,United
R16656 T21905 T21896 arg3Of ),(
R16657 T21906 T21911 modOf and,using
R16658 T21908 T21907 arg1Of reactions,colorimetric
R16659 T21908 T21909 arg1Of reactions,were
R1666 T2072 T2065 arg2Of domain,and
R16660 T21908 T21910 arg2Of reactions,read
R16661 T21910 T21906 arg2Of read,and
R16662 T21910 T21909 arg2Of read,were
R16663 T21911 T21927 arg1Of using,at
R16664 T21915 T21911 arg2Of reader,using
R16665 T21915 T21912 arg1Of reader,a
R16666 T21915 T21913 arg1Of reader,VersaMax
R16667 T21915 T21914 arg1Of reader,microplate
R16668 T21915 T21916 arg1Of reader,(
R16669 T21918 T21917 arg1Of Devices,Molecular
R1667 T2072 T2067 arg1Of domain,factor-κB
R16670 T21918 T21919 arg1Of Devices,","
R16671 T21919 T21921 arg1Of ",",","
R16672 T21920 T21919 arg2Of Sunnyvale,","
R16673 T21921 T21923 arg1Of ",",","
R16674 T21922 T21921 arg2Of California,","
R16675 T21923 T21916 arg2Of ",",(
R16676 T21925 T21923 arg2Of States,","
R16677 T21925 T21924 arg1Of States,United
R16678 T21926 T21916 arg3Of ),(
R16679 T21929 T21927 arg2Of absorbance,at
R1668 T2072 T2071 arg1Of domain,binding
R16680 T21929 T21928 arg1Of absorbance,an
R16681 T21929 T21930 arg1Of absorbance,of
R16682 T21932 T21930 arg2Of nm,of
R16683 T21932 T21931 arg1Of nm,750
R16684 T21934 T21933 arg1Of fractionation,Size
R16685 T21934 T21935 arg1Of fractionation,was
R16686 T21934 T21936 arg2Of fractionation,performed
R16687 T21936 T21935 arg2Of performed,was
R16688 T21936 T21937 arg1Of performed,on
R16689 T21936 T21945 arg1Of performed,and
R1669 T2072 T2073 arg1Of domain,","
R16690 T21939 T21937 arg2Of μg,on
R16691 T21939 T21938 arg1Of μg,20
R16692 T21939 T21940 arg1Of μg,of
R16693 T21939 T21942 arg1Of μg,by
R16694 T21941 T21940 arg2Of protein/sample,of
R16695 T21943 T21942 arg2Of SDS-PAGE,by
R16696 T21945 T21944 arg1Of and,","
R16697 T21947 T21946 arg1Of protein,the
R16698 T21947 T21948 arg1Of protein,was
R16699 T21947 T21949 arg2Of protein,transferred
R1670 T1974 T1972 arg3Of ],[
R16700 T21947 T21956 arg2Of protein,subjected
R16701 T21949 T21950 arg1Of transferred,to
R16702 T21949 T21955 arg1Of transferred,and
R16703 T21951 T21952 arg1Of nitrocellulose,or
R16704 T21953 T21952 arg2Of PVDF,or
R16705 T21954 T21950 arg2Of membranes,to
R16706 T21954 T21951 arg1Of membranes,nitrocellulose
R16707 T21954 T21953 arg1Of membranes,PVDF
R16708 T21955 T21945 arg2Of and,and
R16709 T21955 T21948 arg2Of and,was
R1671 T2076 T2073 arg2Of region,","
R16710 T21956 T21955 arg2Of subjected,and
R16711 T21956 T21957 arg1Of subjected,to
R16712 T21956 T21959 modOf subjected,using
R16713 T21958 T21957 arg2Of immunoblotting,to
R16714 T21962 T21959 arg2Of antibodies,using
R16715 T21962 T21960 arg1Of antibodies,the
R16716 T21962 T21961 arg1Of antibodies,indicated
R16717 T21963 T21964 arg1Of Foxp3,was
R16718 T21963 T21965 arg2Of Foxp3,detected
R16719 T21965 T21964 arg2Of detected,was
R1672 T2076 T2074 arg1Of region,a
R16720 T21966 T21965 arg3Of using,detected
R16721 T21968 T21967 arg1Of anti-human,rabbit
R16722 T21971 T21968 arg1Of antibody,anti-human
R16723 T21971 T21969 arg1Of antibody,Foxp3
R16724 T21971 T21970 arg1Of antibody,polyclonal
R16725 T21971 T21972 arg1Of antibody,(
R16726 T21971 T21984 arg1Of antibody,and
R16727 T21973 T21974 arg1Of ab4728,or
R16728 T21974 T21972 arg2Of or,(
R16729 T21974 T21976 arg1Of or,;
R1673 T2076 T2075 arg1Of region,central
R16730 T21975 T21974 arg2Of ab10563,or
R16731 T21977 T21976 arg2Of Abcam,;
R16732 T21977 T21978 arg1Of Abcam,","
R16733 T21977 T21980 arg1Of Abcam,","
R16734 T21979 T21978 arg2Of Cambridge,","
R16735 T21982 T21980 arg2Of Kingdom,","
R16736 T21982 T21981 arg1Of Kingdom,United
R16737 T21983 T21972 arg3Of ),(
R16738 T21984 T21966 arg2Of and,using
R16739 T21984 T21989 arg1Of and,(
R1674 T1975 T1953 arg3Of ),(
R16740 T21988 T21984 arg2Of antibody,and
R16741 T21988 T21985 arg1Of antibody,anti-rabbit
R16742 T21988 T21986 arg1Of antibody,IgG-HRP
R16743 T21988 T21987 arg1Of antibody,secondary
R16744 T21992 T21990 arg1Of Technology,Cell
R16745 T21992 T21991 arg1Of Technology,Signaling
R16746 T21992 T21993 arg1Of Technology,","
R16747 T21993 T21995 arg1Of ",",","
R16748 T21994 T21993 arg2Of Beverly,","
R16749 T21995 T21997 arg1Of ",",","
R1675 T2076 T2077 arg1Of region,containing
R16750 T21996 T21995 arg2Of Massachusetts,","
R16751 T21998 T21997 arg2Of United,","
R16752 T21999 T21989 arg2Of States,(
R16753 T21999 T21992 arg1Of States,Technology
R16754 T21999 T21994 arg1Of States,Beverly
R16755 T21999 T21996 arg1Of States,Massachusetts
R16756 T21999 T21998 arg1Of States,United
R16757 T22000 T21989 arg3Of ),(
R16758 T22002 T22003 arg1Of p65,and
R16759 T22003 T22001 arg1Of and,NF-κB
R1676 T1976 T1949 arg2Of and,of
R16760 T22003 T22005 arg1Of and,were
R16761 T22003 T22006 arg2Of and,detected
R16762 T22004 T22003 arg2Of CREB-1,and
R16763 T22006 T22005 arg2Of detected,were
R16764 T22007 T22006 arg3Of using,detected
R16765 T22010 T22008 arg1Of polyclonal,rabbit
R16766 T22010 T22009 arg1Of polyclonal,anti-human
R16767 T22012 T22010 arg1Of p65,polyclonal
R16768 T22012 T22011 arg2Of p65,(
R16769 T22012 T22014 arg1Of p65,or
R1677 T2080 T2081 arg1Of finger,and
R16770 T22013 T22011 arg3Of ),(
R16771 T22014 T22007 arg2Of or,using
R16772 T22014 T22022 arg1Of or,(
R16773 T22016 T22014 arg2Of antibody,or
R16774 T22016 T22015 arg1Of antibody,monoclonal
R16775 T22016 T22017 arg1Of antibody,(
R16776 T22018 T22017 arg2Of CREB-1,(
R16777 T22018 T22019 arg1Of CREB-1,;
R16778 T22020 T22019 arg2Of 48H2,;
R16779 T22021 T22017 arg3Of ),(
R1678 T1979 T1976 arg2Of disorders,and
R16780 T22025 T22022 arg2Of Technology,(
R16781 T22025 T22023 arg1Of Technology,Cell
R16782 T22025 T22024 arg1Of Technology,Signaling
R16783 T22026 T22022 arg3Of ),(
R16784 T22027 T22028 arg1Of Beta-actin,was
R16785 T22027 T22029 arg2Of Beta-actin,detected
R16786 T22027 T22030 arg1Of Beta-actin,using
R16787 T22029 T22028 arg2Of detected,was
R16788 T22030 T22029 arg3Of using,detected
R16789 T22034 T22030 arg2Of antibody,using
R1679 T2082 T2081 arg2Of leucine,and
R16790 T22034 T22031 arg1Of antibody,a
R16791 T22034 T22032 arg1Of antibody,mouse
R16792 T22034 T22033 arg1Of antibody,monoclonal
R16793 T22034 T22035 arg1Of antibody,(
R16794 T22036 T22035 arg2Of AC-15,(
R16795 T22036 T22037 arg1Of AC-15,;
R16796 T22038 T22039 arg1Of Sigma,","
R16797 T22039 T22042 arg1Of ",",","
R16798 T22041 T22039 arg2Of Louis,","
R16799 T22041 T22040 arg1Of Louis,St.
R1680 T2083 T2077 arg2Of zipper,containing
R16800 T22042 T22044 arg1Of ",",","
R16801 T22043 T22042 arg2Of Missouri,","
R16802 T22044 T22037 arg2Of ",",;
R16803 T22046 T22044 arg2Of States,","
R16804 T22046 T22045 arg1Of States,United
R16805 T22047 T22035 arg3Of ),(
R16806 T22050 T22048 arg2Of analysis,For
R16807 T22050 T22049 arg1Of analysis,coimmunoprecipitation
R16808 T22053 T22052 arg1Of lysates,cell
R16809 T22053 T22054 arg1Of lysates,were
R1681 T2083 T2078 arg1Of zipper,a
R16810 T22053 T22055 arg2Of lysates,precleared
R16811 T22053 T22079 arg2Of lysates,incubated
R16812 T22055 T22056 arg1Of precleared,with
R16813 T22055 T22077 arg1Of precleared,and
R16814 T22058 T22056 arg2Of μl,with
R16815 T22058 T22057 arg1Of μl,30
R16816 T22058 T22059 arg1Of μl,of
R16817 T22063 T22059 arg2Of beads,of
R16818 T22063 T22060 arg1Of beads,protein
R16819 T22063 T22061 arg1Of beads,A/G
R1682 T2083 T2079 arg1Of zipper,zinc
R16820 T22063 T22062 arg1Of beads,plus-agarose
R16821 T22063 T22064 arg1Of beads,(
R16822 T22067 T22065 arg1Of Biotechnology,Santa
R16823 T22067 T22066 arg1Of Biotechnology,Cruz
R16824 T22067 T22068 arg1Of Biotechnology,","
R16825 T22068 T22071 arg1Of ",",","
R16826 T22070 T22068 arg2Of Cruz,","
R16827 T22070 T22069 arg1Of Cruz,Santa
R16828 T22071 T22064 arg2Of ",",(
R16829 T22071 T22073 arg1Of ",",","
R1683 T2083 T2080 arg1Of zipper,finger
R16830 T22072 T22071 arg2Of California,","
R16831 T22075 T22073 arg2Of States,","
R16832 T22075 T22074 arg1Of States,United
R16833 T22076 T22064 arg3Of ),(
R16834 T22077 T22048 arg1Of and,For
R16835 T22077 T22051 arg1Of and,","
R16836 T22077 T22054 arg2Of and,were
R16837 T22079 T22077 arg2Of incubated,and
R16838 T22079 T22078 arg1Of incubated,then
R16839 T22079 T22080 arg1Of incubated,with
R1684 T2083 T2082 arg1Of zipper,leucine
R16840 T22084 T22081 arg1Of antibody,mouse
R16841 T22084 T22082 arg1Of antibody,monoclonal
R16842 T22084 T22083 arg1Of antibody,anti-HA
R16843 T22084 T22085 arg1Of antibody,(
R16844 T22084 T22096 arg1Of antibody,and
R16845 T22086 T22087 arg1Of 6E2,;
R16846 T22087 T22085 arg2Of ;,(
R16847 T22087 T22089 arg1Of ;,:
R16848 T22088 T22087 arg2Of 1,;
R16849 T22090 T22091 arg1Of 100,;
R1685 T2083 T2085 arg1Of zipper,important
R16850 T22091 T22089 arg2Of ;,:
R16851 T22094 T22091 arg2Of Technology,;
R16852 T22094 T22092 arg1Of Technology,Cell
R16853 T22094 T22093 arg1Of Technology,Signaling
R16854 T22095 T22085 arg3Of ),(
R16855 T22096 T22080 arg2Of and,with
R16856 T22098 T22096 arg2Of μl,and
R16857 T22098 T22097 arg1Of μl,30
R16858 T22098 T22099 arg1Of μl,of
R16859 T22103 T22099 arg2Of beads,of
R1686 T2085 T2084 arg1Of important,potentially
R16860 T22103 T22100 arg1Of beads,protein
R16861 T22103 T22101 arg1Of beads,A/G
R16862 T22103 T22102 arg1Of beads,plus-agarose
R16863 T22103 T22104 arg1Of beads,overnight
R16864 T22106 T22105 arg1Of immunoprecipitates,The
R16865 T22106 T22107 arg1Of immunoprecipitates,were
R16866 T22106 T22108 arg2Of immunoprecipitates,washed
R16867 T22106 T22122 arg2Of immunoprecipitates,heated
R16868 T22108 T22121 arg1Of washed,and
R16869 T22110 T22108 arg3Of times,washed
R1687 T2085 T2086 arg1Of important,for
R16870 T22110 T22109 arg1Of times,four
R16871 T22110 T22111 arg1Of times,with
R16872 T22110 T22115 arg2Of times,resuspended
R16873 T22113 T22111 arg2Of buffer,with
R16874 T22113 T22112 arg1Of buffer,RIPA
R16875 T22115 T22114 arg1Of resuspended,","
R16876 T22115 T22116 arg1Of resuspended,in
R16877 T22119 T22116 arg2Of buffer,in
R16878 T22119 T22117 arg1Of buffer,SDS
R16879 T22119 T22118 arg1Of buffer,sample
R1688 T2088 T2086 arg2Of interactions,for
R16880 T22121 T22107 arg2Of and,were
R16881 T22121 T22120 arg1Of and,","
R16882 T22122 T22121 arg2Of heated,and
R16883 T22122 T22123 arg1Of heated,at
R16884 T22122 T22126 arg1Of heated,for
R16885 T22125 T22123 arg2Of °C,at
R16886 T22125 T22124 arg1Of °C,95
R16887 T22128 T22126 arg2Of min,for
R16888 T22128 T22127 arg1Of min,5
R16889 T22129 T22130 arg1Of Proteins,were
R1689 T2088 T2087 arg1Of interactions,protein-protein
R16890 T22129 T22132 arg2Of Proteins,treated
R16891 T22132 T22130 arg2Of treated,were
R16892 T22132 T22131 arg1Of treated,then
R16893 T22132 T22133 arg1Of treated,as
R16894 T22134 T22133 arg2Of described,as
R16895 T22134 T22135 arg1Of described,for
R16896 T22138 T22135 arg2Of analysis,for
R16897 T22138 T22136 arg1Of analysis,Western
R16898 T22138 T22137 arg1Of analysis,blot
R1690 T1979 T1977 arg1Of disorders,virus-induced
R1691 T2090 T2054 arg2Of and,as
R1692 T2090 T2089 arg1Of and,","
R1693 T1979 T1978 arg1Of disorders,immunologic
R1694 T1979 T1980 arg1Of disorders,(
R1695 T2095 T2094 arg2Of FKH,(
R1696 T1987 T1981 arg1Of type,e.g.
R1697 T2096 T2094 arg3Of ),(
R1698 T2097 T2090 arg2Of domain,and
R1699 T2097 T2091 arg1Of domain,a
R1700 T2097 T2092 arg1Of domain,carboxyl-terminal
R1701 T2097 T2093 arg1Of domain,forkhead
R1702 T2097 T2094 arg1Of domain,(
R1703 T2097 T2098 arg2Of domain,required
R1704 T2098 T2099 arg1Of required,for
R1705 T2101 T2100 arg1Of localization,nuclear
R1706 T2101 T2102 arg1Of localization,and
R1707 T2102 T2099 arg2Of and,for
R1708 T2104 T2102 arg2Of activity,and
R17082 T22449 T22446 arg1Of analysis,Transcription
R17083 T22449 T22447 arg1Of analysis,factor
R17084 T22449 T22448 arg1Of analysis,DNA-binding
R17085 T22449 T22450 arg1Of analysis,(
R17086 T22451 T22450 arg2Of TF-ELISA,(
R17087 T22452 T22450 arg3Of ),(
R17088 T22453 T22454 arg1Of CREB-1,and
R17089 T22455 T22454 arg2Of ATF-2,and
R1709 T2104 T2103 arg1Of activity,DNA-binding
R17090 T22457 T22453 arg1Of activity,CREB-1
R17091 T22457 T22455 arg1Of activity,ATF-2
R17092 T22457 T22456 arg1Of activity,DNA-binding
R17093 T22457 T22458 arg1Of activity,was
R17094 T22457 T22459 arg2Of activity,analyzed
R17095 T22459 T22458 arg2Of analyzed,was
R17096 T22459 T22460 arg1Of analyzed,with
R17097 T22459 T22473 arg1Of analyzed,according
R17098 T22465 T22464 arg2Of Inflammation,(
R17099 T22465 T22466 arg1Of Inflammation,1
R1710 T2104 T2105 arg1Of activity,[
R17100 T22467 T22464 arg3Of ),(
R17101 T22468 T22460 arg2Of Kit,with
R17102 T22468 T22461 arg1Of Kit,the
R17103 T22468 T22462 arg1Of Kit,TransFactor
R17104 T22468 T22463 arg1Of Kit,Profiling
R17105 T22468 T22464 arg1Of Kit,(
R17106 T22468 T22469 arg1Of Kit,(
R17107 T22470 T22469 arg2Of BD,(
R17108 T22470 T22471 arg1Of BD,Biosciences
R17109 T22472 T22469 arg3Of ),(
R1711 T2106 T2105 arg2Of 14–16,[
R17110 T22474 T22473 arg2Of to,according
R17111 T22476 T22475 arg1Of manufacturer,the
R17112 T22476 T22477 arg2Of manufacturer,'s
R17113 T22478 T22474 arg2Of protocol,to
R17114 T22478 T22477 arg1Of protocol,'s
R17115 T22480 T22479 arg1Of extracts,Nuclear
R17116 T22480 T22481 arg1Of extracts,were
R17117 T22480 T22482 arg2Of extracts,prepared
R17118 T22480 T22517 arg1Of extracts,using
R17119 T22482 T22481 arg2Of prepared,were
R1712 T2107 T2105 arg3Of ],[
R17120 T22482 T22483 arg1Of prepared,from
R17121 T22482 T22517 modOf prepared,using
R17122 T22486 T22484 arg1Of cells,HEK
R17123 T22486 T22485 arg1Of cells,293T
R17124 T22486 T22487 arg2Of cells,transfected
R17125 T22486 T22495 arg1Of cells,or
R17126 T22487 T22488 arg1Of transfected,with
R17127 T22491 T22488 arg2Of vector,with
R17128 T22491 T22489 arg1Of vector,a
R17129 T22491 T22490 arg1Of vector,control
R1713 T2109 T2108 arg1Of inactivation,Functional
R17130 T22491 T22492 arg1Of vector,(
R17131 T22493 T22492 arg2Of EGFP,(
R17132 T22494 T22492 arg3Of ),(
R17133 T22495 T22483 arg2Of or,from
R17134 T22495 T22503 arg1Of or,in
R17135 T22495 T22510 arg1Of or,(
R17136 T22498 T22495 arg2Of vector,or
R17137 T22498 T22496 arg1Of vector,Foxp3
R17138 T22498 T22497 arg1Of vector,expression
R17139 T22498 T22499 arg1Of vector,(
R1714 T2109 T2110 arg1Of inactivation,of
R17140 T22501 T22499 arg2Of ng,(
R17141 T22501 T22500 arg1Of ng,"1,000"
R17142 T22502 T22499 arg3Of ),(
R17143 T22505 T22506 arg1Of presence,or
R17144 T22506 T22503 arg2Of or,in
R17145 T22506 T22504 arg1Of or,the
R17146 T22506 T22508 arg1Of or,of
R17147 T22507 T22506 arg2Of absence,or
R17148 T22509 T22508 arg2Of forskolin,of
R17149 T22512 T22510 arg2Of μM,(
R1715 T2109 T2140 arg2Of inactivation,reported
R17150 T22512 T22511 arg1Of μM,10
R17151 T22512 T22513 arg1Of μM,for
R17152 T22515 T22513 arg2Of h,for
R17153 T22515 T22514 arg1Of h,4
R17154 T22516 T22510 arg3Of ),(
R17155 T22521 T22517 arg2Of Kit,using
R17156 T22521 T22518 arg1Of Kit,the
R17157 T22521 T22519 arg1Of Kit,TransFactor
R17158 T22521 T22520 arg1Of Kit,Extraction
R17159 T22521 T22522 arg1Of Kit,(
R1716 T2109 T2146 arg1Of inactivation,results
R17160 T22524 T22522 arg2Of Biosciences,(
R17161 T22524 T22523 arg1Of Biosciences,BD
R17162 T22525 T22522 arg3Of ),(
R17163 T22527 T22526 arg1Of concentration,Protein
R17164 T22527 T22528 arg1Of concentration,was
R17165 T22527 T22529 arg2Of concentration,determined
R17166 T22529 T22528 arg2Of determined,was
R17167 T22530 T22529 arg3Of using,determined
R17168 T22532 T22530 arg2Of Biophotometer,using
R17169 T22532 T22531 arg1Of Biophotometer,a
R1717 T1987 T1982 arg1Of type,","
R17170 T22532 T22533 arg1Of Biophotometer,(
R17171 T22534 T22535 arg1Of Eppendorf,","
R17172 T22535 T22533 arg2Of ",",(
R17173 T22535 T22537 arg1Of ",",","
R17174 T22536 T22535 arg2Of Hamburg,","
R17175 T22538 T22537 arg2Of Germany,","
R17176 T22539 T22533 arg3Of ),(
R17177 T22541 T22540 arg1Of extracts,Nuclear
R17178 T22541 T22542 arg1Of extracts,(
R17179 T22541 T22546 arg1Of extracts,were
R1718 T1987 T1983 arg1Of type,human
R17180 T22541 T22547 arg2Of extracts,incubated
R17181 T22544 T22542 arg2Of μg,(
R17182 T22544 T22543 arg1Of μg,20
R17183 T22545 T22542 arg3Of ),(
R17184 T22547 T22546 arg2Of incubated,were
R17185 T22547 T22548 arg1Of incubated,in
R17186 T22550 T22548 arg2Of wells,in
R17187 T22550 T22549 arg2Of wells,preblocked
R17188 T22550 T22551 arg1Of wells,containing
R17189 T22554 T22551 arg2Of oligonucleotides,containing
R1719 T1987 T1984 arg1Of type,T
R17190 T22554 T22552 arg1Of oligonucleotides,plate-bound
R17191 T22554 T22553 arg1Of oligonucleotides,double-stranded
R17192 T22554 T22555 arg1Of oligonucleotides,corresponding
R17193 T22555 T22556 arg1Of corresponding,to
R17194 T22560 T22556 arg2Of sequence,to
R17195 T22560 T22557 arg1Of sequence,an
R17196 T22560 T22558 arg1Of sequence,ATF/CREB
R17197 T22560 T22559 arg1Of sequence,consensus
R17198 T22560 T22561 arg1Of sequence,(
R17199 T22562 T22561 arg2Of …TGACATCA…,(
R1720 T1987 T1985 arg1Of type,lymphotropic
R17200 T22563 T22561 arg3Of ),(
R17201 T22564 T22565 arg1Of Wells,were
R17202 T22564 T22566 arg2Of Wells,washed
R17203 T22564 T22568 arg2Of Wells,incubated
R17204 T22564 T22577 arg2Of Wells,incubated
R17205 T22564 T22585 arg1Of Wells,washed
R17206 T22564 T22590 arg2Of Wells,developed
R17207 T22566 T22567 arg1Of washed,","
R17208 T22567 T22576 arg1Of ",",","
R17209 T22568 T22567 arg2Of incubated,","
R1721 T1987 T1986 arg1Of type,virus
R17210 T22568 T22569 arg1Of incubated,with
R17211 T22573 T22569 arg2Of antibody,with
R17212 T22573 T22570 arg1Of antibody,the
R17213 T22573 T22571 arg1Of antibody,appropriate
R17214 T22573 T22572 arg1Of antibody,primary
R17215 T22573 T22574 arg1Of antibody,","
R17216 T22573 T22575 arg2Of antibody,washed
R17217 T22576 T22565 arg2Of ",",were
R17218 T22576 T22584 arg1Of ",",","
R17219 T22577 T22576 arg2Of incubated,","
R1722 T1987 T1988 arg1Of type,I
R17220 T22577 T22578 arg1Of incubated,with
R17221 T22580 T22578 arg2Of antibody,with
R17222 T22580 T22579 arg1Of antibody,secondary
R17223 T22580 T22581 arg1Of antibody,(
R17224 T22582 T22581 arg2Of HRP-labeled,(
R17225 T22583 T22581 arg3Of ),(
R17226 T22584 T22587 arg1Of ",",","
R17227 T22584 T22588 arg1Of ",",and
R17228 T22585 T22584 arg2Of washed,","
R17229 T22585 T22586 arg1Of washed,again
R1723 T1990 T1989 arg2Of HTLV-I,[
R17230 T22590 T22588 arg2Of developed,and
R17231 T22590 T22589 arg1Of developed,finally
R17232 T22590 T22591 arg1Of developed,with
R17233 T22593 T22591 arg2Of substrate,with
R17234 T22593 T22592 arg1Of substrate,TMB
R17235 T22595 T22594 arg1Of reactions,Colorimetric
R17236 T22595 T22596 arg1Of reactions,were
R17237 T22595 T22597 arg2Of reactions,read
R17238 T22597 T22596 arg2Of read,were
R17239 T22597 T22598 modOf read,using
R1724 T2111 T2112 arg1Of Foxp3,by
R17240 T22598 T22607 arg1Of using,at
R17241 T22602 T22598 arg2Of reader,using
R17242 T22602 T22599 arg1Of reader,a
R17243 T22602 T22600 arg1Of reader,VersaMax
R17244 T22602 T22601 arg1Of reader,microplate
R17245 T22602 T22603 arg1Of reader,(
R17246 T22605 T22603 arg2Of Devices,(
R17247 T22605 T22604 arg1Of Devices,Molecular
R17248 T22606 T22603 arg3Of ),(
R17249 T22609 T22607 arg2Of absorbance,at
R1725 T2111 T2126 arg1Of Foxp3,or
R17250 T22609 T22608 arg1Of absorbance,an
R17251 T22609 T22610 arg1Of absorbance,of
R17252 T22612 T22610 arg2Of nm,of
R17253 T22612 T22611 arg1Of nm,655
R1726 T1991 T1989 arg3Of ],[
R1727 T2114 T2112 arg2Of mutations,by
R1728 T2114 T2113 arg1Of mutations,genetic
R1729 T2114 T2115 arg1Of mutations,affecting
R1730 T2115 T2120 arg1Of affecting,","
R1731 T2115 T2121 arg1Of affecting,as
R1732 T1995 T1987 arg1Of paraparesis,type
R1733 T2119 T2115 arg2Of region,affecting
R1734 T2119 T2116 arg1Of region,the
R1735 T2119 T2117 arg1Of region,Foxp3
R1736 T2119 T2118 arg1Of region,coding
R1737 T2122 T2121 arg2Of demonstrated,as
R1738 T2122 T2123 arg1Of demonstrated,in
R1739 T1995 T1989 arg1Of paraparesis,[
R1740 T2124 T2123 arg2Of IPEX,in
R1741 T1995 T1992 arg1Of paraparesis,-associated
R1742 T1995 T1993 arg1Of paraparesis,myelopathy/tropical
R1743 T2126 T2110 arg2Of or,of
R1744 T2126 T2125 arg1Of or,","
R1745 T2127 T2126 arg2Of repression,or
R1746 T2127 T2128 arg1Of repression,of
R1747 T2127 T2131 arg1Of repression,by
R1748 T2130 T2128 arg2Of expression,of
R1749 T2130 T2129 arg1Of expression,Foxp3
R1750 T1995 T1994 arg1Of paraparesis,spastic
R1751 T1995 T1996 arg1Of paraparesis,[
R1752 T1995 T2000 arg1Of paraparesis,and
R17520 T22964 T22962 arg1Of analysis,Flow
R17521 T22964 T22963 arg1Of analysis,cytometric
R17522 T22964 T22965 arg1Of analysis,of
R17523 T22968 T22967 arg1Of expression,protein
R17524 T22968 T22965 arg2Of expression,of
R17525 T22968 T22966 arg1Of expression,Foxp3
R17526 T22970 T22969 arg2Of PBMCs,Cryopreserved
R17527 T22970 T22971 arg1Of PBMCs,from
R17528 T22970 T22977 arg1Of PBMCs,were
R17529 T22970 T22978 arg2Of PBMCs,thawed
R1753 T1997 T1996 arg2Of HAM/TSP,[
R17530 T22970 T22980 arg2Of PBMCs,washed
R17531 T22973 T22972 arg1Of patients,HAM/TSP
R17532 T22973 T22974 arg1Of patients,or
R17533 T22974 T22971 arg2Of or,from
R17534 T22976 T22974 arg2Of ACs,or
R17535 T22976 T22975 arg1Of ACs,HTLV-I-infected
R17536 T22978 T22979 arg1Of thawed,and
R17537 T22979 T22977 arg2Of and,were
R17538 T22979 T22981 arg1Of and,with
R17539 T22980 T22979 arg2Of washed,and
R1754 T2136 T2131 arg2Of Tax,by
R17540 T22983 T22981 arg2Of buffer,with
R17541 T22983 T22982 arg1Of buffer,FACS
R17542 T22983 T22984 arg1Of buffer,(
R17543 T22986 T22984 arg2Of PBS,(
R17544 T22986 T22985 arg1Of PBS,1×
R17545 T22986 T22987 arg1Of PBS,","
R17546 T22986 T22991 arg1Of PBS,","
R17547 T22988 T22989 arg1Of 0.1,%
R17548 T22990 T22987 arg2Of NaN3,","
R17549 T22990 T22988 arg1Of NaN3,0.1
R1755 T2136 T2132 arg1Of Tax,the
R17550 T22992 T22993 arg1Of 5,%
R17551 T22994 T22991 arg2Of FBS,","
R17552 T22994 T22992 arg1Of FBS,5
R17553 T22995 T22984 arg3Of ),(
R17554 T22996 T22997 arg1Of Cells,(
R17555 T22996 T23002 arg1Of Cells,were
R17556 T22996 T23003 arg2Of Cells,fixed
R17557 T22998 T22999 arg1Of 1.5,×
R17558 T22999 T22997 arg2Of ×,(
R17559 T23000 T22999 arg2Of 106,×
R1756 T2136 T2133 arg1Of Tax,HTLV-I-encoded
R17560 T23001 T22997 arg3Of ),(
R17561 T23003 T23002 arg2Of fixed,were
R17562 T23007 T23003 arg1Of fixation,fixed
R17563 T23007 T23004 arg2Of fixation,by
R17564 T23007 T23005 arg1Of fixation,sequential
R17565 T23007 T23006 arg1Of fixation,formaldehyde/methanol
R17566 T23007 T23008 arg1Of fixation,as
R17567 T23009 T23008 arg2Of follows,as
R17568 T23010 T23011 arg1Of Cells,were
R17569 T23010 T23013 arg2Of Cells,resuspended
R1757 T2136 T2134 arg1Of Tax,transactivator
R17570 T23010 T23018 arg2Of Cells,fixed
R17571 T23013 T23014 arg1Of resuspended,in
R17572 T23013 T23017 arg1Of resuspended,and
R17573 T23016 T23014 arg2Of buffer,in
R17574 T23016 T23015 arg1Of buffer,FACS
R17575 T23017 T23011 arg2Of and,were
R17576 T23017 T23012 arg1Of and,carefully
R17577 T23018 T23017 arg2Of fixed,and
R17578 T23018 T23019 arg1Of fixed,with
R17579 T23021 T23019 arg2Of μl,with
R1758 T2136 T2135 arg1Of Tax,protein
R17580 T23021 T23020 arg1Of μl,100
R17581 T23021 T23022 arg1Of μl,of
R17582 T23024 T23022 arg2Of A,of
R17583 T23024 T23023 arg1Of A,reagent
R17584 T23028 T23026 arg1Of Perm,Fix
R17585 T23028 T23027 arg1Of Perm,&
R17586 T23029 T23018 arg3Of kit,fixed
R17587 T23029 T23025 arg1Of kit,(
R17588 T23029 T23028 arg1Of kit,Perm
R17589 T23029 T23030 arg1Of kit,;
R1759 T2140 T2138 arg2Of reported,as
R17590 T23032 T23031 arg1Of Laboratories,Caltag
R17591 T23032 T23033 arg1Of Laboratories,","
R17592 T23033 T23035 arg1Of ",",","
R17593 T23034 T23033 arg2Of Burlingame,","
R17594 T23035 T23037 arg1Of ",",","
R17595 T23036 T23035 arg2Of California,","
R17596 T23037 T23040 arg1Of ",",)
R17597 T23037 T23041 arg1Of ",",at
R17598 T23037 T23062 arg1Of ",",were
R17599 T23037 T23063 arg2Of ",",washed
R1760 T2140 T2139 arg1Of reported,recently
R17600 T23037 T23066 arg2Of ",",permeabilized
R17601 T23037 T23080 arg2Of ",",stained
R17602 T23039 T23037 arg2Of States,","
R17603 T23039 T23038 arg1Of States,United
R17604 T23043 T23041 arg2Of temperature,at
R17605 T23043 T23042 arg1Of temperature,room
R17606 T23043 T23044 arg1Of temperature,for
R17607 T23046 T23044 arg2Of min,for
R17608 T23046 T23045 arg1Of min,3
R17609 T23046 T23047 arg2Of min,followed
R1761 T2140 T2141 arg1Of reported,in
R17610 T23047 T23048 arg1Of followed,by
R17611 T23047 T23055 arg1Of followed,for
R17612 T23050 T23048 arg2Of ml,by
R17613 T23050 T23049 arg1Of ml,2
R17614 T23050 T23051 arg1Of ml,of
R17615 T23052 T23053 arg1Of 70,%
R17616 T23054 T23051 arg2Of methanol,of
R17617 T23054 T23052 arg1Of methanol,70
R17618 T23057 T23055 arg2Of min,for
R17619 T23057 T23056 arg1Of min,5
R1762 T1998 T1996 arg3Of ],[
R17620 T23057 T23058 arg1Of min,at
R17621 T23061 T23058 arg2Of Cells,at
R17622 T23061 T23059 arg1Of Cells,4
R17623 T23061 T23060 arg1Of Cells,°C.
R17624 T23063 T23064 arg1Of washed,twice
R17625 T23063 T23065 arg1Of washed,and
R17626 T23065 T23030 arg2Of and,;
R17627 T23065 T23062 arg2Of and,were
R17628 T23066 T23067 arg1Of permeabilized,with
R17629 T23066 T23073 arg1Of permeabilized,(
R1763 T2142 T2141 arg2Of patients,in
R17630 T23066 T23079 arg1Of permeabilized,and
R17631 T23069 T23067 arg2Of μl,with
R17632 T23069 T23068 arg1Of μl,100
R17633 T23069 T23070 arg1Of μl,of
R17634 T23072 T23070 arg2Of B,of
R17635 T23072 T23071 arg1Of B,reagent
R17636 T23076 T23074 arg1Of Perm,Fix
R17637 T23076 T23075 arg1Of Perm,&
R17638 T23077 T23073 arg2Of kit,(
R17639 T23077 T23076 arg1Of kit,Perm
R1764 T2142 T2143 arg1Of patients,with
R17640 T23078 T23073 arg3Of ),(
R17641 T23079 T23065 arg2Of and,and
R17642 T23080 T23079 arg2Of stained,and
R17643 T23080 T23081 arg1Of stained,for
R17644 T23080 T23103 arg1Of stained,for
R17645 T23083 T23081 arg2Of Foxp3,for
R17646 T23083 T23082 arg1Of Foxp3,intracellular
R17647 T23083 T23084 arg1Of Foxp3,with
R17648 T23089 T23085 arg1Of antibody,mouse
R17649 T23089 T23086 arg1Of antibody,anti-human
R1765 T2000 T1980 arg2Of and,(
R17650 T23089 T23087 arg1Of antibody,Foxp3
R17651 T23089 T23088 arg1Of antibody,monoclonal
R17652 T23089 T23090 arg1Of antibody,(
R17653 T23089 T23098 arg1Of antibody,or
R17654 T23092 T23090 arg2Of μg,(
R17655 T23092 T23091 arg1Of μg,0.5
R17656 T23092 T23093 arg1Of μg,of
R17657 T23092 T23095 arg1Of μg,;
R17658 T23094 T23093 arg2Of ab22510,of
R17659 T23096 T23095 arg2Of Abcam,;
R1766 T2144 T2143 arg2Of HAM/TSP,with
R17660 T23097 T23090 arg3Of ),(
R17661 T23098 T23084 arg2Of or,with
R17662 T23102 T23098 arg2Of control,or
R17663 T23102 T23099 arg1Of control,the
R17664 T23102 T23100 arg1Of control,appropriate
R17665 T23102 T23101 arg1Of control,isotype
R17666 T23105 T23103 arg2Of min,for
R17667 T23105 T23104 arg1Of min,30
R17668 T23106 T23107 arg1Of Cells,were
R17669 T23106 T23108 arg2Of Cells,washed
R1767 T2146 T2137 arg1Of results,","
R17670 T23106 T23111 arg2Of Cells,stained
R17671 T23108 T23109 arg1Of washed,twice
R17672 T23108 T23110 arg1Of washed,and
R17673 T23110 T23107 arg2Of and,were
R17674 T23111 T23110 arg2Of stained,and
R17675 T23111 T23112 arg1Of stained,with
R17676 T23111 T23128 arg1Of stained,for
R17677 T23117 T23113 arg1Of F,Cy5-conjugated
R17678 T23117 T23114 arg1Of F,goat
R17679 T23117 T23115 arg1Of F,anti-mouse
R1768 T2146 T2138 arg1Of results,as
R17680 T23117 T23116 arg1Of F,immunoglobulin
R17681 T23117 T23118 arg1Of F,(
R17682 T23119 T23118 arg2Of ab′,(
R17683 T23120 T23118 arg3Of ),(
R17684 T23123 T23112 arg2Of antibody,with
R17685 T23123 T23117 arg1Of antibody,F
R17686 T23123 T23121 arg1Of antibody,2
R17687 T23123 T23122 arg1Of antibody,secondary
R17688 T23123 T23124 arg1Of antibody,(
R17689 T23126 T23124 arg2Of Laboratories,(
R1769 T2146 T2145 arg1Of results,","
R17690 T23126 T23125 arg1Of Laboratories,Caltag
R17691 T23127 T23124 arg3Of ),(
R17692 T23132 T23128 arg2Of min,for
R17693 T23132 T23129 arg1Of min,an
R17694 T23132 T23130 arg1Of min,additional
R17695 T23132 T23131 arg1Of min,30
R17696 T23133 T23134 arg1Of Cells,were
R17697 T23133 T23135 arg2Of Cells,washed
R17698 T23133 T23138 arg2Of Cells,stained
R17699 T23135 T23136 arg1Of washed,twice
R1770 T2146 T2147 arg1Of results,in
R17700 T23135 T23137 arg1Of washed,and
R17701 T23137 T23134 arg2Of and,were
R17702 T23138 T23137 arg2Of stained,and
R17703 T23138 T23139 arg1Of stained,for
R17704 T23142 T23139 arg2Of expression,for
R17705 T23142 T23140 arg1Of expression,surface
R17706 T23142 T23141 arg1Of expression,CD4
R17707 T23142 T23143 arg1Of expression,with
R17708 T23145 T23144 arg1Of anti-CD4,PE-labeled
R17709 T23145 T23146 arg1Of anti-CD4,(
R1771 T2148 T2147 arg2Of loss,in
R17710 T23145 T23149 arg1Of anti-CD4,and
R17711 T23147 T23146 arg2Of BD,(
R17712 T23148 T23146 arg3Of ),(
R17713 T23149 T23143 arg2Of and,with
R17714 T23151 T23149 arg2Of expression,and
R17715 T23151 T23150 arg1Of expression,CD25
R17716 T23151 T23152 arg1Of expression,with
R17717 T23154 T23152 arg2Of anti-CD25,with
R17718 T23154 T23153 arg1Of anti-CD25,FITC-labeled
R17719 T23154 T23155 arg1Of anti-CD25,(
R1772 T2148 T2149 arg1Of loss,of
R17720 T23156 T23155 arg2Of BD,(
R17721 T23157 T23155 arg3Of ),(
R17722 T23158 T23159 arg1Of Cells,were
R17723 T23158 T23160 arg2Of Cells,washed
R17724 T23158 T23163 arg2Of Cells,analyzed
R17725 T23160 T23161 arg1Of washed,twice
R17726 T23160 T23162 arg1Of washed,and
R17727 T23162 T23159 arg2Of and,were
R17728 T23163 T23162 arg2Of analyzed,and
R17729 T23163 T23164 arg1Of analyzed,on
R1773 T2148 T2152 arg1Of loss,in
R17730 T23166 T23164 arg2Of FACSCalibur,on
R17731 T23166 T23165 arg1Of FACSCalibur,a
R17732 T23166 T23167 arg1Of FACSCalibur,(
R17733 T23168 T23167 arg2Of BD,(
R17734 T23169 T23167 arg3Of ),(
R17735 T23171 T23170 arg1Of analysis,Data
R17736 T23171 T23172 arg1Of analysis,was
R17737 T23171 T23173 arg2Of analysis,performed
R17738 T23173 T23172 arg2Of performed,was
R17739 T23174 T23173 arg3Of using,performed
R1774 T2000 T1999 arg1Of and,","
R17740 T23175 T23174 arg2Of FlowJo,using
R17741 T23175 T23176 arg1Of FlowJo,(
R17742 T23178 T23177 arg1Of Star,Tree
R17743 T23178 T23179 arg1Of Star,","
R17744 T23179 T23181 arg1Of ",",","
R17745 T23180 T23179 arg2Of Ashland,","
R17746 T23181 T23183 arg1Of ",",","
R17747 T23182 T23181 arg2Of Oregon,","
R17748 T23183 T23176 arg2Of ",",(
R17749 T23185 T23183 arg2Of States,","
R1775 T2002 T2000 arg2Of AIDS,and
R17750 T23185 T23184 arg1Of States,United
R17751 T23186 T23176 arg3Of ),(
R1776 T2151 T2149 arg2Of activity,of
R1777 T2151 T2150 arg1Of activity,regulatory
R1778 T2002 T2001 arg1Of AIDS,HIV-induced
R1779 T2155 T2152 arg2Of cells,in
R17791 T23299 T23298 arg1Of analyses,Statistical
R17792 T23302 T23301 arg1Of U,Mann-Whitney
R17793 T23303 T23300 arg1Of test,The
R17794 T23303 T23302 arg1Of test,U
R17795 T23303 T23304 arg1Of test,was
R17796 T23303 T23305 arg2Of test,used
R17797 T23305 T23304 arg2Of used,was
R17798 T23307 T23305 arg3Of compare,used
R17799 T23307 T23306 arg1Of compare,to
R1780 T2155 T2153 arg1Of cells,CD4+CD25hi
R17800 T23309 T23307 arg2Of data,compare
R17801 T23309 T23308 arg1Of data,the
R17802 T23309 T23310 arg1Of data,between
R17803 T23311 T23310 arg2Of patients,between
R17804 T23311 T23312 arg1Of patients,with
R17805 T23313 T23314 arg1Of HAM/TSP,and
R17806 T23314 T23312 arg2Of and,with
R17807 T23315 T23314 arg2Of AC,and
R1781 T2002 T2003 arg1Of AIDS,[
R1782 T2004 T2003 arg2Of 8–10,[
R1783 T2155 T2154 arg1Of cells,T
R1784 T2155 T2156 arg1Of cells,[
R1785 T2157 T2156 arg2Of "4,8,17",[
R1786 T2158 T2156 arg3Of ],[
R1787 T2005 T2003 arg3Of ],[
R1788 T2006 T1980 arg3Of ),(
R1789 T2161 T2159 arg2Of is,Although
R1790 T2162 T2161 arg2Of clear,is
R1791 T2010 T2007 arg1Of Foxp3,The
R1792 T2164 T2165 arg1Of Foxp3,regulates
R1793 T2165 T2160 arg1Of regulates,it
R1794 T2165 T2161 arg1Of regulates,is
R1795 T2165 T2162 arg1Of regulates,clear
R1796 T2165 T2163 arg1Of regulates,that
R1797 T2168 T2166 arg1Of proliferation,T
R1798 T2168 T2167 arg1Of proliferation,cell
R1799 T2168 T2169 arg1Of proliferation,and
R1800 T2169 T2165 arg2Of and,regulates
R1801 T2171 T2169 arg2Of production,and
R1802 T2171 T2170 arg1Of production,cytokine
R1803 T2174 T2173 arg1Of little,very
R1804 T2174 T2175 arg1Of little,is
R1805 T2174 T2176 arg2Of little,known
R1806 T2010 T2008 arg1Of Foxp3,transcription
R1807 T2010 T2009 arg1Of Foxp3,factor
R1808 T2176 T2159 arg1Of known,Although
R1809 T2176 T2172 arg1Of known,","
R1810 T2176 T2175 arg2Of known,is
R1811 T2176 T2177 arg1Of known,concerning
R1812 T2010 T2011 arg1Of Foxp3,is
R1813 T2180 T2177 arg2Of mechanisms,concerning
R1814 T2180 T2178 arg1Of mechanisms,the
R1815 T2180 T2179 arg1Of mechanisms,molecular
R1816 T2180 T2181 arg1Of mechanisms,of
R1817 T2010 T2029 arg1Of Foxp3,has
R1818 T2010 T2031 arg1Of Foxp3,been
R1819 T2183 T2181 arg2Of function,of
R1820 T2183 T2182 arg1Of function,Foxp3
R1821 T2010 T2032 arg2Of Foxp3,shown
R1822 T2010 T2034 arg1Of Foxp3,be
R1823 T2186 T2184 arg1Of evidence,The
R1824 T2010 T2036 arg1Of Foxp3,critical
R1825 T2186 T2185 arg1Of evidence,first
R1826 T2186 T2187 modOf evidence,to
R1827 T2186 T2200 arg1Of evidence,came
R1828 T2011 T2028 arg1Of is,and
R1829 T2188 T2187 arg1Of indicate,to
R1830 T2189 T2188 arg2Of how,indicate
R1831 T2190 T2191 arg1Of Foxp3,promotes
R1832 T2191 T2189 arg1Of promotes,how
R1833 T2207 T2206 arg2Of colleagues,and
R1834 T2193 T2194 arg1Of development,and
R1835 T2194 T2191 arg2Of and,promotes
R1836 T2194 T2192 arg1Of and,the
R1837 T2194 T2196 arg1Of and,of
R1838 T2195 T2194 arg2Of function,and
R1839 T2199 T2196 arg2Of cells,of
R1840 T2199 T2197 arg1Of cells,regulatory
R1841 T2199 T2198 arg1Of cells,T
R1842 T2200 T2201 arg1Of came,from
R1843 T2200 T2211 arg1Of came,","
R1844 T2200 T2212 arg1Of came,which
R1845 T2200 T2213 arg1Of came,suggested
R1846 T2203 T2201 arg2Of report,from
R1847 T2203 T2202 arg1Of report,a
R1848 T2203 T2204 arg1Of report,by
R1849 T2205 T2206 arg1Of Ziegler,and
R1850 T2207 T2208 arg1Of colleagues,[
R1851 T2206 T2204 arg2Of and,by
R1852 T2209 T2208 arg2Of 16,[
R1853 T2210 T2208 arg3Of ],[
R1854 T2215 T2216 arg1Of Foxp3,could
R1855 T2304 T2303 arg2Of colleagues,and
R1856 T2215 T2217 arg1Of Foxp3,inhibit
R1857 T2217 T2213 arg2Of inhibit,suggested
R1858 T2304 T2305 arg1Of colleagues,[
R1859 T2306 T2305 arg2Of 15,[
R1860 T2217 T2214 arg1Of inhibit,that
R1861 T2307 T2305 arg3Of ],[
R1862 T2217 T2216 arg2Of inhibit,could
R1863 T2217 T2220 arg1Of inhibit,by
R1864 T2309 T2308 arg1Of demonstrated,further
R1865 T2219 T2217 arg2Of activation,inhibit
R1866 T2311 T2312 arg1Of Foxp3,could
R1867 T2311 T2313 arg1Of Foxp3,inhibit
R1868 T2313 T2309 arg2Of inhibit,demonstrated
R1869 T2313 T2310 arg1Of inhibit,that
R1870 T2313 T2312 arg2Of inhibit,could
R1871 T2313 T2320 arg1Of inhibit,","
R1872 T2313 T2321 arg1Of inhibit,although
R1873 T2314 T2317 arg1Of NF-AT,as
R1874 T2219 T2218 arg1Of activation,transcriptional
R1875 T2222 T2220 arg2Of interacting,by
R1876 T2317 T2315 arg1Of as,as
R1877 T2317 T2316 arg1Of as,well
R1878 T2318 T2317 arg2Of NF-κB,as
R1879 T2319 T2313 arg2Of activation,inhibit
R1880 T2319 T2314 arg1Of activation,NF-AT
R1881 T2319 T2318 arg1Of activation,NF-κB
R1882 T2222 T2221 arg1Of interacting,physically
R1883 T2222 T2223 arg1Of interacting,with
R1884 T2323 T2322 arg1Of mechanism,the
R1885 T2323 T2324 arg1Of mechanism,of
R1886 T2323 T2326 arg1Of mechanism,was
R1887 T2323 T2327 arg2Of mechanism,shown
R1888 T2323 T2329 arg1Of mechanism,involve
R1889 T2226 T2223 arg2Of sites,with
R1890 T2325 T2324 arg2Of suppression,of
R1891 T2327 T2321 arg2Of shown,although
R1892 T2327 T2326 arg2Of shown,was
R1893 T2329 T2327 arg3Of involve,shown
R1894 T2329 T2328 arg1Of involve,to
R1895 T2331 T2330 arg1Of protein-protein,direct
R1896 T2332 T2329 arg2Of interactions,involve
R1897 T2332 T2331 arg1Of interactions,protein-protein
R1898 T2332 T2333 arg1Of interactions,between
R1899 T2332 T2347 arg1Of interactions,adjacent
R1900 T2334 T2335 arg1Of NF-AT,or
R1901 T2335 T2340 arg1Of or,than
R1902 T2336 T2337 arg1Of NF-κB,and
R1903 T2226 T2224 arg1Of sites,forkhead
R1904 T2337 T2335 arg2Of and,or
R1905 T2226 T2225 arg1Of sites,binding
R1906 T2338 T2337 arg2Of Foxp3,and
R1907 T2226 T2227 arg1Of sites,located
R1908 T2226 T2229 arg1Of sites,adjacent
R1909 T2340 T2333 arg2Of than,between
R1910 T2340 T2339 arg1Of than,rather
R1911 T2341 T2340 arg2Of binding,than
R1912 T2341 T2342 arg1Of binding,of
R1913 T2341 T2344 arg1Of binding,to
R1914 T2229 T2228 arg1Of adjacent,immediately
R1915 T2343 T2342 arg2Of Foxp3,of
R1916 T2346 T2344 arg2Of elements,to
R1917 T2346 T2345 arg1Of elements,promoter
R1918 T2347 T2348 arg1Of adjacent,to
R1919 T2229 T2230 arg1Of adjacent,to
R1920 T2350 T2351 arg1Of NF-AT,or
R1921 T2235 T2230 arg2Of sites,to
R1922 T2352 T2351 arg2Of NF-κB,or
R1923 T2353 T2348 arg2Of sites,to
R1924 T2353 T2349 arg1Of sites,cis-acting
R1925 T2353 T2350 arg1Of sites,NF-AT
R1926 T2353 T2352 arg1Of sites,NF-κB
R1927 T2357 T2356 arg1Of data,these
R1928 T2357 T2358 arg1Of data,suggested
R1929 T2358 T2354 arg1Of suggested,Collectively
R1930 T2358 T2355 arg1Of suggested,","
R1931 T2360 T2361 arg1Of Foxp3,may
R1932 T2360 T2362 arg1Of Foxp3,function
R1933 T2235 T2231 arg1Of sites,critical
R1934 T2362 T2358 arg2Of function,suggested
R1935 T2362 T2359 arg1Of function,that
R1936 T2362 T2361 arg2Of function,may
R1937 T2362 T2363 arg1Of function,as
R1938 T2362 T2367 arg1Of function,","
R1939 T2362 T2368 arg1Of function,potentially
R1940 T2362 T2369 arg1Of function,through
R1941 T2235 T2232 arg1Of sites,cis-acting
R1942 T2235 T2233 arg1Of sites,NF-AT
R1943 T2366 T2363 arg2Of repressor,as
R1944 T2366 T2364 arg1Of repressor,a
R1945 T2366 T2365 arg1Of repressor,transcriptional
R1946 T2235 T2234 arg1Of sites,binding
R1947 T2371 T2369 arg2Of formation,through
R1948 T2371 T2370 arg1Of formation,the
R1949 T2371 T2372 arg1Of formation,of
R1950 T2235 T2236 arg2Of sites,found
R1951 T2235 T2241 arg1Of sites,(
R1952 T2236 T2237 arg1Of found,in
R1953 T2240 T2237 arg2Of promoters,in
R1954 T2374 T2375 arg1Of DNA-protein,and
R1955 T2375 T2373 arg1Of and,both
R1956 T2376 T2375 arg2Of protein-protein,and
R1957 T2377 T2372 arg2Of interactions,of
R1958 T2377 T2374 arg1Of interactions,DNA-protein
R1959 T2377 T2376 arg1Of interactions,protein-protein
R1960 T2240 T2238 arg1Of promoters,various
R1961 T2240 T2239 arg1Of promoters,cytokine
R1962 T2245 T2241 arg2Of promoter,(
R1963 T2381 T2378 arg2Of study,In
R1964 T2381 T2379 arg1Of study,the
R1965 T2381 T2380 arg1Of study,present
R1966 T2383 T2384 arg1Of we,expanded
R1967 T2383 T2389 arg1Of we,defining
R1968 T2383 T2400 arg1Of we,investigated
R1969 T2384 T2385 arg1Of expanded,upon
R1970 T2384 T2388 arg1Of expanded,by
R1971 T2384 T2399 arg1Of expanded,and
R1972 T2387 T2385 arg2Of observations,upon
R1973 T2387 T2386 arg1Of observations,these
R1974 T2245 T2242 arg1Of promoter,e.g.
R1975 T2389 T2388 arg2Of defining,by
R1976 T2245 T2243 arg1Of promoter,","
R1977 T2245 T2244 arg1Of promoter,IL-2
R1978 T2391 T2389 arg2Of requirements,defining
R1979 T2391 T2390 arg1Of requirements,additional
R1980 T2391 T2392 arg1Of requirements,of
R1981 T2246 T2241 arg3Of ),(
R1982 T2394 T2392 arg2Of repression,of
R1983 T2394 T2393 arg1Of repression,Foxp3-mediated
R1984 T2394 T2395 arg1Of repression,of
R1985 T2248 T2247 arg1Of study,That
R1986 T2397 T2395 arg2Of activation,of
R1987 T2397 T2396 arg1Of activation,NF-κB
R1988 T2399 T2378 arg1Of and,In
R1989 T2399 T2382 arg1Of and,","
R1990 T2399 T2398 arg1Of and,","
R1991 T2400 T2399 arg2Of investigated,and
R1992 T2248 T2250 arg1Of study,demonstrated
R1993 T2250 T2249 arg1Of demonstrated,also
R1994 T2252 T2253 arg1Of Foxp3,could
R1995 T2402 T2403 arg1Of Foxp3,could
R1996 T2402 T2404 arg1Of Foxp3,target
R1997 T2404 T2400 arg2Of target,investigated
R1998 T2404 T2401 arg1Of target,whether
R1999 T2404 T2403 arg2Of target,could
R2000 T2404 T2408 arg1Of target,by
R2001 T2407 T2404 arg2Of pathways,target
R2002 T2407 T2405 arg1Of pathways,additional
R2003 T2407 T2406 arg1Of pathways,signaling
R2004 T2252 T2254 arg1Of Foxp3,repress
R2005 T2409 T2408 arg2Of examining,by
R2006 T2254 T2250 arg2Of repress,demonstrated
R2007 T2411 T2409 arg2Of activation,examining
R2008 T2411 T2410 arg1Of activation,transcriptional
R2009 T2411 T2412 arg1Of activation,of
R2010 T2413 T2414 arg1Of NF-κB-dependent,and
R2011 T2254 T2251 arg1Of repress,that
R2012 T2254 T2253 arg2Of repress,could
R2013 T2415 T2414 arg2Of NF-κB-independent,and
R2014 T2255 T2254 arg2Of activation,repress
R2015 T2417 T2412 arg2Of pathogens,of
R2016 T2417 T2413 arg1Of pathogens,NF-κB-dependent
R2017 T2417 T2415 arg1Of pathogens,NF-κB-independent
R2018 T2417 T2416 arg1Of pathogens,retroviral
R2019 T2255 T2256 arg1Of activation,of
R2020 T2419 T2418 arg1Of characterization,The
R2021 T2419 T2420 arg1Of characterization,of
R2022 T2419 T2426 arg1Of characterization,and
R2023 T2260 T2256 arg2Of vector,of
R2024 T2423 T2420 arg2Of targets,of
R2025 T2423 T2421 arg1Of targets,the
R2026 T2423 T2422 arg1Of targets,molecular
R2027 T2423 T2424 arg1Of targets,of
R2028 T2425 T2424 arg2Of Foxp3,of
R2029 T2426 T2432 arg2Of and,utilized
R2030 T2426 T2449 arg1Of and,Tregs
R2031 T2260 T2257 arg1Of vector,a
R2032 T2260 T2258 arg1Of vector,synthetic
R2033 T2428 T2426 arg2Of mechanism,and
R2034 T2428 T2427 arg1Of mechanism,the
R2035 T2428 T2429 arg1Of mechanism,(
R2036 T2260 T2259 arg1Of vector,reporter
R2037 T2430 T2429 arg2Of s,(
R2038 T2260 T2261 arg1Of vector,containing
R2039 T2431 T2429 arg3Of ),(
R2040 T2264 T2263 arg1Of promoter,SV40
R2041 T2434 T2432 arg1Of Foxp3,utilized
R2042 T2434 T2433 arg2Of Foxp3,by
R2043 T2434 T2442 arg2Of Foxp3,aid
R2044 T2436 T2435 arg1Of support,to
R2045 T2436 T2441 arg1Of support,will
R2046 T2436 T2442 arg1Of support,aid
R2047 T2438 T2439 arg1Of development,and
R2048 T2439 T2436 arg2Of and,support
R2049 T2439 T2437 arg1Of and,Treg
R2050 T2440 T2439 arg2Of function,and
R2051 T2442 T2441 arg2Of aid,will
R2052 T2442 T2443 arg1Of aid,in
R2053 T2264 T2265 arg1Of promoter,and
R2054 T2265 T2261 arg2Of and,containing
R2055 T2445 T2443 arg2Of understanding,in
R2056 T2445 T2444 arg1Of understanding,our
R2057 T2445 T2446 arg1Of understanding,of
R2058 T2265 T2262 arg1Of and,an
R2059 T2448 T2446 arg2Of role,of
R2060 T2448 T2447 arg1Of role,the
R2061 T2449 T2451 arg1Of Tregs,in
R2062 T2265 T2269 arg1Of and,of
R2063 T2450 T2449 arg2Of play,Tregs
R2064 T2268 T2265 arg2Of copies,and
R2065 T2453 T2451 arg2Of pathogenesis,in
R2066 T2453 T2452 arg1Of pathogenesis,the
R2067 T2453 T2454 arg1Of pathogenesis,of
R2068 T2268 T2266 arg1Of copies,three
R2069 T2268 T2267 arg1Of copies,tandem
R2070 T2273 T2269 arg2Of site,of
R2071 T2457 T2454 arg2Of disease,of
R2072 T2457 T2455 arg1Of disease,human
R2073 T2457 T2456 arg1Of disease,autoimmune
R2074 T2273 T2270 arg1Of site,a
R2075 T2273 T2271 arg1Of site,forkhead
R2076 T2273 T2272 arg1Of site,binding
R2077 T2275 T2274 arg1Of results,These
R2079 T2275 T2276 arg1Of results,provided
R2080 T2276 T2279 modOf provided,suggesting
R2082 T2278 T2276 arg2Of evidence,provided
R2083 T2278 T2277 arg1Of evidence,additional
R2084 T2283 T2281 arg1Of repression,Foxp3
R2085 T2283 T2282 arg1Of repression,transcriptional
R2086 T2283 T2284 arg1Of repression,was
R2087 T2283 T2285 arg2Of repression,mediated
R2088 T2285 T2279 arg2Of mediated,suggesting
R2089 T2285 T2280 arg1Of mediated,that
R2090 T2285 T2284 arg2Of mediated,was
R2091 T2285 T2288 arg1Of mediated,in
R2092 T2285 T2292 arg1Of mediated,to
R2093 T2287 T2285 arg1Of binding,mediated
R2094 T2287 T2286 arg2Of binding,by
R2095 T2291 T2288 arg2Of manner,in
R2096 T2291 T2289 arg1Of manner,a
R2097 T2291 T2290 arg1Of manner,sequence-specific
R2098 T2293 T2292 arg2Of promoters,to
R2099 T2293 T2294 arg1Of promoters,containing
R2100 T2297 T2294 arg2Of sites,containing
R2101 T2297 T2295 arg1Of sites,forkhead
R2102 T2297 T2296 arg1Of sites,binding
R2103 T2300 T2298 arg1Of study,A
R2104 T2300 T2299 arg1Of study,recent
R2105 T2300 T2301 arg1Of study,by
R2106 T2300 T2309 arg1Of study,demonstrated
R2107 T2302 T2303 arg1Of Bettelli,and
R2108 T2303 T2301 arg2Of and,by
R2738 T3430 T3431 arg1Of Foxp3,Suppresses
R2739 T3435 T3431 arg2Of Activation,Suppresses
R2740 T3435 T3432 arg1Of Activation,NF-κB
R2741 T3435 T3433 arg1Of Activation,Dependent
R2742 T3435 T3434 arg1Of Activation,Transcriptional
R2743 T3437 T3436 arg1Of ascertain,To
R2744 T3440 T3437 arg2Of mechanisms,ascertain
R2745 T3440 T3438 arg1Of mechanisms,the
R2746 T3440 T3439 arg1Of mechanisms,molecular
R2747 T3444 T3441 arg2Of functions,by
R2748 T3444 T3442 arg1Of functions,which
R2749 T3444 T3443 arg1Of functions,Foxp3
R2750 T3444 T3445 modOf functions,to
R2751 T3446 T3445 arg1Of promote,to
R2752 T3449 T3446 arg2Of function,promote
R2753 T3449 T3447 arg1Of function,the
R2754 T3449 T3448 arg1Of function,regulatory
R2755 T3449 T3450 arg1Of function,of
R2756 T3453 T3450 arg2Of cells,of
R2757 T3453 T3451 arg1Of cells,CD4+CD25hi
R2758 T3453 T3452 arg1Of cells,T
R2759 T3455 T3437 arg1Of we,ascertain
R2760 T3455 T3457 arg1Of we,confirmed
R2761 T3457 T3436 modOf confirmed,To
R2762 T3457 T3441 arg1Of confirmed,by
R2763 T3457 T3454 arg1Of confirmed,","
R2764 T3457 T3456 arg1Of confirmed,first
R2765 T3457 T3462 arg1Of confirmed,as
R2766 T3459 T3457 arg2Of function,confirmed
R2767 T3459 T3458 arg1Of function,the
R2768 T3459 T3460 arg1Of function,of
R2769 T3461 T3460 arg2Of Foxp3,of
R2770 T3464 T3462 arg2Of repressor,as
R2771 T3464 T3463 arg1Of repressor,a
R2772 T3464 T3465 arg1Of repressor,of
R2773 T3464 T3469 arg1Of repressor,","
R2774 T3464 T3471 arg2Of repressor,implicated
R2775 T3466 T3465 arg2Of activation,of
R2776 T3466 T3467 arg1Of activation,of
R2777 T3468 T3467 arg2Of NF-κB,of
R2778 T3471 T3470 arg1Of implicated,previously
R2779 T3471 T3472 arg1Of implicated,as
R2780 T3471 T3488 arg1Of implicated,[
R2781 T3474 T3472 arg2Of target,as
R2782 T3474 T3473 arg1Of target,a
R2783 T3474 T3475 arg1Of target,of
R2784 T3480 T3475 arg2Of factors,of
R2785 T3480 T3476 arg1Of factors,other
R2786 T3480 T3477 arg1Of factors,forkhead/winged-helix
R2787 T3480 T3478 arg1Of factors,family
R2788 T3480 T3479 arg1Of factors,transcription
R2789 T3480 T3481 arg1Of factors,(
R2790 T3484 T3485 arg1Of Foxj1,and
R2791 T3485 T3481 arg2Of and,(
R2792 T3485 T3482 arg1Of and,e.g.
R2793 T3485 T3483 arg1Of and,","
R2794 T3486 T3485 arg2Of Foxo3a,and
R2795 T3487 T3481 arg3Of ),(
R2796 T3489 T3488 arg2Of "19,20",[
R2797 T3490 T3488 arg3Of ],[
R2798 T3491 T3492 arg1Of We,analyzed
R2799 T3494 T3492 arg2Of effect,analyzed
R2800 T3494 T3493 arg1Of effect,the
R2801 T3494 T3495 arg1Of effect,of
R2802 T3494 T3498 arg1Of effect,on
R2803 T3497 T3495 arg2Of overexpression,of
R2804 T3497 T3496 arg1Of overexpression,Foxp3
R2805 T3500 T3498 arg2Of activation,on
R2806 T3500 T3499 arg1Of activation,NF-κB
R2807 T3500 T3501 arg1Of activation,in
R2808 T3500 T3505 arg1Of activation,in
R2809 T3504 T3501 arg2Of cells,in
R2810 T3504 T3502 arg1Of cells,HEK
R2811 T3504 T3503 arg1Of cells,293T
R2812 T3506 T3507 arg1Of dose-response,and
R2813 T3508 T3507 arg2Of time,and
R2814 T3510 T3505 arg2Of analyses,in
R2815 T3510 T3506 arg1Of analyses,dose-response
R2816 T3510 T3508 arg1Of analyses,time
R2817 T3510 T3509 arg1Of analyses,course
R2818 T3511 T3512 arg1Of Transfection,of
R2819 T3511 T3516 arg1Of Transfection,with
R2820 T3511 T3522 arg1Of Transfection,in
R2821 T3511 T3535 arg1Of Transfection,or
R2822 T3515 T3512 arg2Of cells,of
R2823 T3515 T3513 arg1Of cells,HEK
R2824 T3515 T3514 arg1Of cells,293T
R2825 T3521 T3516 arg2Of vector,with
R2826 T3521 T3517 arg1Of vector,an
R2827 T3521 T3518 arg1Of vector,NF-κB
R2828 T3521 T3519 arg1Of vector,luciferase
R2829 T3521 T3520 arg1Of vector,reporter
R2830 T3524 T3525 arg1Of presence,or
R2831 T3525 T3522 arg2Of or,in
R2832 T3525 T3523 arg1Of or,the
R2833 T3525 T3527 arg1Of or,of
R2834 T3526 T3525 arg2Of absence,or
R2835 T3529 T3527 arg2Of concentrations,of
R2836 T3529 T3528 arg1Of concentrations,increasing
R2837 T3529 T3530 arg1Of concentrations,of
R2838 T3534 T3530 arg2Of vector,of
R2839 T3534 T3531 arg1Of vector,a
R2840 T3534 T3532 arg1Of vector,Foxp3
R2841 T3534 T3533 arg1Of vector,expression
R2842 T3535 T3548 arg1Of or,was
R2843 T3535 T3549 arg2Of or,performed
R2844 T3538 T3535 arg2Of vector,or
R2845 T3538 T3536 arg1Of vector,a
R2846 T3538 T3537 arg1Of vector,control
R2847 T3538 T3539 arg1Of vector,(
R2848 T3543 T3539 arg2Of protein,(
R2849 T3543 T3540 arg2Of protein,enhanced
R2850 T3543 T3541 arg1Of protein,green
R2851 T3543 T3542 arg1Of protein,fluorescent
R2852 T3543 T3544 arg1Of protein,[
R2853 T3545 T3544 arg2Of EGFP,[
R2854 T3546 T3544 arg3Of ],[
R2855 T3547 T3539 arg3Of ),(
R2856 T3549 T3548 arg2Of performed,was
R2857 T3549 T3551 arg1Of performed,and
R2858 T3551 T3550 arg1Of and,","
R2859 T3552 T3553 arg1Of cells,were
R2860 T3552 T3554 arg2Of cells,harvested
R2861 T3554 T3551 arg2Of harvested,and
R2862 T3554 T3553 arg2Of harvested,were
R2863 T3554 T3555 arg1Of harvested,after
R2864 T3554 T3558 modOf harvested,to
R2865 T3557 T3555 arg2Of h,after
R2866 T3557 T3556 arg1Of h,24
R2867 T3559 T3558 arg1Of assay,to
R2868 T3559 T3560 arg1Of assay,for
R2869 T3562 T3561 arg1Of activity,luciferase
R2870 T3562 T3563 arg1Of activity,and
R2871 T3563 T3560 arg2Of and,for
R2872 T3566 T3563 arg2Of expression,and
R2873 T3566 T3564 arg1Of expression,Foxp3
R2874 T3566 T3565 arg1Of expression,mRNA
R2875 T3567 T3568 arg1Of Results,indicated
R2876 T3572 T3571 arg1Of concentration,the
R2877 T3572 T3573 arg1Of concentration,of
R2878 T3572 T3578 arg1Of concentration,increases
R2879 T3574 T3573 arg2Of Foxp3,of
R2880 T3574 T3575 arg2Of Foxp3,transfected
R2881 T3575 T3576 arg1Of transfected,into
R2882 T3577 T3576 arg2Of cells,into
R2883 T3578 T3570 arg2Of increases,as
R2884 T3578 T3579 arg1Of increases,(
R2885 T3580 T3579 arg2Of from,(
R2886 T3581 T3582 arg1Of 50,to
R2887 T3583 T3582 arg2Of "2,400",to
R2888 T3584 T3580 arg2Of ng,from
R2889 T3584 T3581 arg1Of ng,50
R2890 T3585 T3579 arg3Of ),(
R2891 T3588 T3587 arg1Of level,the
R2892 T3588 T3589 arg1Of level,of
R2893 T3588 T3592 arg1Of level,decreases
R2894 T3591 T3589 arg2Of activation,of
R2895 T3591 T3590 arg1Of activation,NF-κB
R2896 T3592 T3568 arg2Of decreases,indicated
R2897 T3592 T3569 arg1Of decreases,that
R2898 T3592 T3570 arg1Of decreases,as
R2899 T3592 T3586 arg1Of decreases,","
R2900 T3593 T3592 arg2Of proportionally,decreases
R2901 T3593 T3594 arg1Of proportionally,(
R2902 T3596 T3594 arg2Of 1A,(
R2903 T3596 T3595 arg1Of 1A,Figure
R2904 T3597 T3594 arg3Of ),(
R2905 T3599 T3598 arg1Of mRNA,Foxp3
R2906 T3599 T3600 arg1Of mRNA,was
R2907 T3599 T3602 arg2Of mRNA,assayed
R2908 T3602 T3600 arg2Of assayed,was
R2909 T3602 T3601 arg1Of assayed,also
R2910 T3602 T3603 modOf assayed,to
R2911 T3604 T3603 arg1Of monitor,to
R2912 T3605 T3604 arg2Of activity,monitor
R2913 T3605 T3606 arg1Of activity,of
R2914 T3610 T3606 arg2Of vector,of
R2915 T3610 T3607 arg1Of vector,the
R2916 T3610 T3608 arg1Of vector,Foxp3
R2917 T3610 T3609 arg1Of vector,expression
R2918 T3610 T3611 arg1Of vector,(
R2919 T3613 T3611 arg2Of 1B,(
R2920 T3613 T3612 arg1Of 1B,Figure
R2921 T3614 T3611 arg3Of ),(
R2922 T3617 T3616 arg1Of activation,NF-κB
R2923 T3617 T3618 arg1Of activation,was
R2924 T3617 T3620 arg2Of activation,affected
R2925 T3620 T3615 arg2Of affected,Since
R2926 T3620 T3618 arg2Of affected,was
R2927 T3620 T3619 arg1Of affected,partially
R2928 T3622 T3620 arg1Of transfection,affected
R2929 T3622 T3621 arg2Of transfection,by
R2930 T3622 T3623 arg1Of transfection,of
R2931 T3625 T3623 arg2Of concentrations,of
R2932 T3625 T3624 arg1Of concentrations,high
R2933 T3625 T3626 arg1Of concentrations,of
R2934 T3629 T3626 arg2Of vector,of
R2935 T3629 T3627 arg1Of vector,the
R2936 T3629 T3628 arg1Of vector,control
R2937 T3631 T3632 arg1Of we,determined
R2938 T3632 T3615 arg1Of determined,Since
R2939 T3632 T3630 arg1Of determined,","
R2940 T3632 T3641 arg1Of determined,compared
R2941 T3635 T3632 arg2Of inhibition,determined
R2942 T3635 T3633 arg1Of inhibition,the
R2943 T3635 T3634 arg1Of inhibition,fold
R2944 T3635 T3636 arg1Of inhibition,of
R2945 T3635 T3639 arg1Of inhibition,by
R2946 T3638 T3636 arg2Of activation,of
R2947 T3638 T3637 arg1Of activation,NF-κB
R2948 T3640 T3639 arg2Of Foxp3,by
R2949 T3642 T3641 arg2Of to,compared
R2950 T3645 T3642 arg2Of vector,to
R2951 T3645 T3643 arg1Of vector,the
R2952 T3645 T3644 arg1Of vector,control
R2953 T3645 T3646 arg1Of vector,at
R2954 T3645 T3649 arg1Of vector,(
R2955 T3648 T3646 arg2Of concentration,at
R2956 T3648 T3647 arg1Of concentration,each
R2957 T3651 T3649 arg2Of 1A,(
R2958 T3651 T3650 arg1Of 1A,Figure
R2959 T3652 T3649 arg3Of ),(
R2960 T3654 T3653 arg1Of inhibition,Fold
R2961 T3654 T3655 arg1Of inhibition,of
R2962 T3654 T3658 arg1Of inhibition,was
R2963 T3654 T3660 arg1Of inhibition,proportional
R2964 T3657 T3655 arg2Of activation,of
R2965 T3657 T3656 arg1Of activation,NF-κB
R2966 T3660 T3658 arg2Of proportional,was
R2967 T3660 T3659 arg1Of proportional,directly
R2968 T3660 T3661 arg1Of proportional,to
R2969 T3663 T3661 arg2Of level,to
R2970 T3663 T3662 arg1Of level,the
R2971 T3663 T3664 arg1Of level,of
R2972 T3667 T3664 arg2Of expression,of
R2973 T3667 T3665 arg1Of expression,Foxp3
R2974 T3667 T3666 arg1Of expression,mRNA
R2975 T3667 T3668 arg2Of expression,detected
R2976 T3671 T3668 arg1Of RT-PCR,detected
R2977 T3671 T3669 arg2Of RT-PCR,by
R2978 T3671 T3670 arg1Of RT-PCR,real-time
R2979 T3673 T3672 arg1Of determine,To
R2980 T3673 T3682 arg1Of determine,over
R2981 T3675 T3673 arg2Of level,determine
R2982 T3675 T3674 arg1Of level,the
R2983 T3675 T3676 arg1Of level,of
R2984 T3678 T3676 arg2Of suppression,of
R2985 T3678 T3677 arg1Of suppression,Foxp3-mediated
R2986 T3678 T3679 arg1Of suppression,of
R2987 T3681 T3679 arg2Of activation,of
R2988 T3681 T3680 arg1Of activation,NF-κB
R2989 T3683 T3682 arg2Of time,over
R2990 T3687 T3685 arg1Of cells,HEK
R2991 T3687 T3686 arg1Of cells,293T
R2992 T3687 T3688 arg1Of cells,were
R2993 T3687 T3689 arg2Of cells,transfected
R2994 T3687 T3709 arg2Of cells,harvested
R2995 T3689 T3690 arg1Of transfected,with
R2996 T3689 T3708 arg1Of transfected,and
R2997 T3695 T3691 arg1Of vector,an
R2998 T3695 T3692 arg1Of vector,NF-κB
R2999 T3695 T3693 arg1Of vector,luciferase
R3000 T3695 T3694 arg1Of vector,reporter
R3001 T3695 T3696 arg1Of vector,and
R3002 T3696 T3690 arg2Of and,with
R3003 T3699 T3696 arg2Of vector,and
R3004 T3699 T3697 arg1Of vector,an
R3005 T3699 T3698 arg1Of vector,expression
R3006 T3699 T3700 arg1Of vector,encoding
R3007 T3701 T3702 arg1Of Foxp3,or
R3008 T3702 T3700 arg2Of or,encoding
R3009 T3702 T3704 arg1Of or,(
R3010 T3703 T3702 arg2Of EGFP,or
R3011 T3706 T3704 arg2Of vector,(
R3012 T3706 T3705 arg1Of vector,control
R3013 T3707 T3704 arg3Of ),(
R3014 T3708 T3672 modOf and,To
R3015 T3708 T3684 arg1Of and,","
R3016 T3708 T3688 arg2Of and,were
R3017 T3709 T3708 arg2Of harvested,and
R3018 T3709 T3710 arg1Of harvested,over
R3019 T3712 T3710 arg2Of d,over
R3020 T3712 T3711 arg1Of d,4
R3021 T3714 T3713 arg2Of shown,As
R3022 T3714 T3715 arg1Of shown,in
R3023 T3717 T3715 arg2Of 1C,in
R3024 T3717 T3716 arg1Of 1C,Figure
R3025 T3720 T3719 arg1Of activation,NF-κB
R3026 T3720 T3721 arg1Of activation,was
R3027 T3720 T3722 arg2Of activation,suppressed
R3028 T3722 T3713 arg1Of suppressed,As
R3029 T3722 T3718 arg1Of suppressed,","
R3030 T3722 T3721 arg2Of suppressed,was
R3031 T3724 T3722 arg1Of overexpression,suppressed
R3032 T3724 T3723 arg2Of overexpression,by
R3033 T3724 T3725 arg1Of overexpression,of
R3034 T3724 T3727 arg1Of overexpression,at
R3035 T3726 T3725 arg2Of Foxp3,of
R3036 T3730 T3727 arg2Of points,at
R3037 T3730 T3728 arg1Of points,all
R3038 T3730 T3729 arg1Of points,time
R3039 T3733 T3731 arg2Of results,Extending
R304 T383 T384 arg1Of Foxp3,Represses
R3040 T3733 T3732 arg1Of results,these
R3041 T3733 T3734 arg1Of results,from
R3042 T3735 T3736 arg1Of established,","
R3043 T3738 T3736 arg2Of vitro,","
R3044 T3738 T3737 arg1Of vitro,in
R3045 T3741 T3734 arg2Of lines,from
R3046 T3741 T3735 arg1Of lines,established
R3047 T3741 T3738 arg1Of lines,vitro
R3048 T3741 T3739 arg1Of lines,HEK
R3049 T3741 T3740 arg1Of lines,cell
R305 T383 T388 arg1Of Foxp3,Targeting
R3050 T3741 T3742 arg1Of lines,to
R3051 T3745 T3742 arg2Of lymphocytes,to
R3052 T3745 T3743 arg1Of lymphocytes,primary
R3053 T3745 T3744 arg1Of lymphocytes,human
R3054 T3747 T3731 arg1Of overexpression,Extending
R3055 T3747 T3748 arg1Of overexpression,of
R3056 T3747 T3750 arg1Of overexpression,in
R3057 T3747 T3760 arg1Of overexpression,down-regulated
R3058 T3749 T3748 arg2Of Foxp3,of
R3059 T3754 T3750 arg2Of cells,in
R306 T384 T387 arg1Of Represses,by
R3060 T3754 T3751 arg2Of cells,purified
R3061 T3754 T3752 arg1Of cells,CD4+
R3062 T3754 T3753 arg1Of cells,T
R3063 T3754 T3755 arg1Of cells,from
R3064 T3758 T3755 arg2Of donors,from
R3065 T3758 T3756 arg1Of donors,three
R3066 T3758 T3757 arg1Of donors,healthy
R3067 T3760 T3731 modOf down-regulated,Extending
R3068 T3760 T3746 arg1Of down-regulated,","
R3069 T3760 T3759 arg1Of down-regulated,also
R307 T397 T396 arg2Of Fox,(
R3070 T3763 T3760 arg2Of level,down-regulated
R3071 T3763 T3761 arg1Of level,the
R3072 T3763 T3762 arg1Of level,steady-state
R3073 T3763 T3764 arg1Of level,of
R3074 T3766 T3764 arg2Of activation,of
R3075 T3766 T3765 arg1Of activation,NF-κB
R3076 T3766 T3767 arg1Of activation,(
R3077 T3769 T3767 arg2Of 1D,(
R3078 T3769 T3768 arg1Of 1D,Figure
R3079 T3770 T3767 arg3Of ),(
R308 T386 T384 arg2Of Transcription,Represses
R3080 T3772 T3771 arg1Of results,These
R3081 T3772 T3773 arg1Of results,recapitulate
R3082 T3773 T3786 arg1Of recapitulate,","
R3083 T3773 T3787 arg1Of recapitulate,in
R3084 T3773 T3789 arg1Of recapitulate,","
R3085 T3773 T3790 modOf recapitulate,to
R3086 T3774 T3775 arg1Of those,from
R3087 T3774 T3777 arg1Of those,and
R3088 T3776 T3775 arg2Of Bettelli,from
R3089 T3777 T3773 arg2Of and,recapitulate
R309 T398 T396 arg3Of ),(
R3090 T3778 T3777 arg2Of colleagues,and
R3091 T3778 T3779 arg1Of colleagues,[
R3092 T3778 T3782 arg1Of colleagues,demonstrating
R3093 T3780 T3779 arg2Of 15,[
R3094 T3781 T3779 arg3Of ],[
R3095 T3785 T3782 arg2Of functions,demonstrating
R3096 T3785 T3783 arg1Of functions,that
R3097 T3785 T3784 arg1Of functions,Foxp3
R3098 T3788 T3787 arg2Of part,in
R3099 T3791 T3790 arg1Of block,to
R310 T386 T385 arg1Of Transcription,Retroviral
R3100 T3793 T3791 arg2Of transcription,block
R3101 T3793 T3792 arg1Of transcription,NF-κB-dependent
R3102 T3793 T3794 arg1Of transcription,in
R3103 T3793 T3801 arg1Of transcription,in
R3104 T3794 T3800 arg1Of in,as
R3105 T3797 T3794 arg2Of lines,in
R3106 T3797 T3795 arg1Of lines,human
R3107 T3797 T3796 arg1Of lines,cell
R3108 T3800 T3798 arg1Of as,as
R3109 T3800 T3799 arg1Of as,well
R311 T401 T394 arg1Of factors,Forkhead
R3110 T3801 T3800 arg2Of in,as
R3111 T3806 T3801 arg2Of cells,in
R3112 T3806 T3802 arg1Of cells,primary
R3113 T3806 T3803 arg1Of cells,human
R3114 T3806 T3804 arg1Of cells,CD4+
R3115 T3806 T3805 arg1Of cells,T
R312 T401 T395 arg1Of factors,box
R313 T401 T396 arg1Of factors,(
R314 T401 T399 arg1Of factors,/winged-helix
R315 T401 T400 arg1Of factors,transcription
R316 T401 T402 arg1Of factors,regulate
R317 T402 T408 arg1Of regulate,and
R318 T388 T387 arg2Of Targeting,by
R319 T404 T402 arg2Of aspects,regulate
R320 T404 T403 arg1Of aspects,multiple
R321 T404 T405 arg1Of aspects,of
R322 T407 T405 arg2Of responsiveness,of
R323 T407 T406 arg1Of responsiveness,immune
R324 T390 T391 arg1Of NF-κB,and
R325 T409 T410 arg1Of Foxp3,is
R326 T409 T411 arg2Of Foxp3,recognized
R327 T411 T408 arg2Of recognized,and
R328 T411 T410 arg2Of recognized,is
R329 T411 T412 arg1Of recognized,as
R330 T391 T388 arg2Of and,Targeting
R331 T391 T389 arg1Of and,Both
R332 T416 T412 arg2Of marker,as
R333 T416 T413 arg1Of marker,an
R334 T416 T414 arg1Of marker,essential
R335 T416 T415 arg1Of marker,functional
R336 T416 T417 arg1Of marker,of
R337 T393 T391 arg2Of Pathways,and
R338 T420 T417 arg2Of cells,of
R339 T420 T418 arg1Of cells,regulatory
R340 T420 T419 arg1Of cells,T
R341 T422 T423 arg1Of we,describe
R342 T393 T392 arg1Of Pathways,CREB
R343 T505 T500 arg2Of cells,or
R344 T423 T421 arg1Of describe,Herein
R345 T426 T423 arg2Of pathways,describe
R346 T426 T424 arg1Of pathways,downstream
R347 T426 T425 arg1Of pathways,signaling
R348 T426 T427 arg2Of pathways,targeted
R349 T429 T427 arg1Of Foxp3,targeted
R350 T429 T428 arg2Of Foxp3,by
R351 T429 T430 arg1Of Foxp3,that
R352 T429 T431 arg1Of Foxp3,may
R353 T429 T433 arg1Of Foxp3,impact
R354 T433 T431 arg2Of impact,may
R355 T433 T432 arg1Of impact,negatively
R356 T435 T433 arg2Of pathogenesis,impact
R357 T435 T434 arg1Of pathogenesis,retroviral
R358 T436 T437 arg1Of Overexpression,of
R359 T436 T439 arg1Of Overexpression,in
R360 T436 T447 arg1Of Overexpression,resulted
R361 T438 T437 arg2Of Foxp3,of
R362 T505 T501 arg1Of cells,primary
R363 T441 T440 arg1Of 293T,HEK
R364 T441 T442 arg1Of 293T,and
R365 T505 T502 arg1Of cells,human
R366 T442 T439 arg2Of and,in
R367 T505 T503 arg1Of cells,CD4+
R368 T505 T504 arg1Of cells,T
R369 T506 T508 arg1Of We,demonstrate
R370 T446 T442 arg2Of cells,and
R3701 T4735 T4732 arg1Of Domain,The
R3702 T4735 T4733 arg1Of Domain,Carboxyl-Terminal
R3703 T4735 T4734 arg1Of Domain,FKH
R3704 T4735 T4736 arg1Of Domain,Is
R3705 T4735 T4738 arg2Of Domain,Required
R3706 T4738 T4736 arg2Of Required,Is
R3707 T4738 T4737 arg1Of Required,Not
R3708 T4738 T4739 arg1Of Required,for
R3709 T4740 T4739 arg2Of Suppression,for
R371 T446 T443 arg2Of cells,purified
R3710 T4740 T4741 arg1Of Suppression,of
R3711 T4743 T4741 arg2Of Activation,of
R3712 T4743 T4742 arg1Of Activation,NF-κB
R3713 T4743 T4744 arg1Of Activation,in
R3714 T4746 T4744 arg2Of Cells,in
R3715 T4746 T4745 arg1Of Cells,T
R3716 T4748 T4747 arg1Of define,To
R3717 T4748 T4753 arg1Of define,with
R3718 T4750 T4748 arg2Of requirements,define
R3719 T4750 T4749 arg1Of requirements,the
R372 T446 T444 arg1Of cells,CD4+
R3720 T4750 T4751 arg1Of requirements,of
R3721 T4752 T4751 arg2Of Foxp3,of
R3722 T4754 T4753 arg2Of respect,with
R3723 T4754 T4755 arg1Of respect,to
R3724 T4756 T4755 arg2Of inhibition,to
R3725 T4756 T4757 arg1Of inhibition,of
R3726 T4759 T4757 arg2Of transcription,of
R3727 T4759 T4758 arg1Of transcription,NF-κB-dependent
R3728 T4761 T4748 arg1Of we,define
R3729 T4761 T4762 arg1Of we,utilized
R373 T446 T445 arg1Of cells,T
R3730 T4762 T4747 modOf utilized,To
R3731 T4762 T4760 arg1Of utilized,","
R3732 T4762 T4798 arg1Of utilized,[
R3733 T4764 T4763 arg1Of mutant,a
R3734 T4764 T4765 arg1Of mutant,of
R3735 T4764 T4788 arg1Of mutant,and
R3736 T4766 T4765 arg2Of Foxp3,of
R3737 T4766 T4767 arg1Of Foxp3,lacking
R3738 T4766 T4778 arg1Of Foxp3,","
R3739 T4766 T4779 arg1Of Foxp3,similar
R374 T447 T448 arg1Of resulted,in
R3740 T4767 T4775 arg1Of lacking,[
R3741 T4770 T4767 arg2Of domain,lacking
R3742 T4770 T4768 arg1Of domain,the
R3743 T4770 T4769 arg1Of domain,FKH
R3744 T4770 T4771 arg1Of domain,(
R3745 T4773 T4771 arg2Of 2A,(
R3746 T4773 T4772 arg1Of 2A,Figure
R3747 T4774 T4771 arg3Of ),(
R3748 T4776 T4775 arg2Of 16,[
R3749 T4777 T4775 arg3Of ],[
R375 T508 T507 arg1Of demonstrate,further
R3750 T4779 T4780 arg1Of similar,to
R3751 T4784 T4780 arg2Of Foxp3,to
R3752 T4784 T4781 arg1Of Foxp3,the
R3753 T4784 T4782 arg1Of Foxp3,scurfy
R3754 T4784 T4783 arg1Of Foxp3,mutant
R3755 T4784 T4785 arg1Of Foxp3,of
R3756 T4786 T4785 arg2Of mice,of
R3757 T4788 T4762 arg2Of and,utilized
R3758 T4788 T4787 arg1Of and,","
R3759 T4792 T4788 arg2Of protein,and
R376 T510 T511 arg1Of Foxp3,suppressed
R3760 T4792 T4789 arg1Of protein,a
R3761 T4792 T4790 arg1Of protein,mutant
R3762 T4792 T4791 arg1Of protein,Foxp3
R3763 T4792 T4793 arg1Of protein,from
R3764 T4795 T4793 arg2Of patient,from
R3765 T4795 T4794 arg1Of patient,a
R3766 T4795 T4796 arg1Of patient,with
R3767 T4797 T4796 arg2Of IPEX,with
R3768 T4799 T4798 arg2Of "4,11,14,17",[
R3769 T4800 T4798 arg3Of ],[
R377 T450 T451 arg1Of dose-dependent,and
R3770 T4803 T4801 arg2Of Foxp3,Unlike
R3771 T4803 T4802 arg1Of Foxp3,full-length
R3772 T4803 T4804 arg1Of Foxp3,","
R3773 T4803 T4805 arg1Of Foxp3,which
R3774 T4803 T4806 arg1Of Foxp3,localizes
R3775 T4803 T4813 arg1Of Foxp3,can
R3776 T4803 T4814 arg1Of Foxp3,bind
R3777 T4806 T4808 arg1Of localizes,exclusively
R3778 T4806 T4809 arg1Of localizes,to
R3779 T4806 T4812 arg1Of localizes,and
R378 T511 T508 arg2Of suppressed,demonstrate
R3780 T4808 T4807 arg1Of exclusively,almost
R3781 T4811 T4809 arg2Of nucleus,to
R3782 T4811 T4810 arg1Of nucleus,the
R3783 T4814 T4812 arg2Of bind,and
R3784 T4814 T4813 arg2Of bind,can
R3785 T4814 T4815 arg1Of bind,in
R3786 T4814 T4819 modOf bind,to
R3787 T4818 T4815 arg2Of manner,in
R3788 T4818 T4816 arg1Of manner,a
R3789 T4818 T4817 arg1Of manner,sequence-specific
R379 T452 T451 arg2Of time-dependent,and
R3790 T4820 T4819 arg1Of forkhead,to
R3791 T4822 T4820 arg2Of sites,forkhead
R3792 T4822 T4821 arg1Of sites,binding
R3793 T4826 T4824 arg1Of mutant,the
R3794 T4826 T4825 arg1Of mutant,ΔFKH
R3795 T4826 T4827 arg1Of mutant,fails
R3796 T4826 T4829 arg1Of mutant,localize
R3797 T4826 T4835 arg1Of mutant,can
R3798 T4826 T4837 arg1Of mutant,interact
R3799 T4827 T4833 arg1Of fails,and
R380 T511 T509 arg1Of suppressed,that
R3800 T4829 T4827 arg2Of localize,fails
R3801 T4829 T4828 arg1Of localize,to
R3802 T4829 T4830 arg1Of localize,to
R3803 T4832 T4830 arg2Of nucleus,to
R3804 T4832 T4831 arg1Of nucleus,the
R3805 T4833 T4801 arg1Of and,Unlike
R3806 T4833 T4823 arg1Of and,","
R3807 T4837 T4833 arg2Of interact,and
R3808 T4837 T4834 arg1Of interact,thus
R3809 T4837 T4835 arg2Of interact,can
R381 T453 T448 arg2Of decrease,in
R3810 T4837 T4836 arg1Of interact,not
R3811 T4837 T4838 arg1Of interact,with
R3812 T4840 T4839 arg1Of elements,promoter
R3813 T4840 T4841 arg1Of elements,or
R3814 T4841 T4838 arg2Of or,with
R3815 T4843 T4841 arg2Of proteins,or
R3816 T4843 T4842 arg1Of proteins,nuclear
R3817 T4843 T4844 arg1Of proteins,[
R3818 T4845 T4844 arg2Of 16,[
R3819 T4846 T4844 arg3Of ],[
R382 T453 T449 arg1Of decrease,a
R3820 T4849 T4850 arg1Of we,utilized
R3821 T4849 T4855 arg1Of we,determine
R3822 T4850 T4847 arg1Of utilized,Therefore
R3823 T4850 T4848 arg1Of utilized,","
R3824 T4850 T4854 modOf utilized,to
R3825 T4853 T4850 arg2Of mutant,utilized
R3826 T4853 T4851 arg1Of mutant,the
R3827 T4853 T4852 arg1Of mutant,ΔFKH
R3828 T4855 T4854 arg1Of determine,to
R3829 T4858 T4857 arg1Of localization,nuclear
R383 T453 T450 arg1Of decrease,dose-dependent
R3830 T4858 T4859 arg1Of localization,(
R3831 T4858 T4869 arg1Of localization,of
R3832 T4858 T4871 arg1Of localization,was
R3833 T4862 T4859 arg2Of function,(
R3834 T4862 T4860 arg1Of function,or
R3835 T4862 T4861 arg1Of function,other
R3836 T4862 T4863 arg2Of function,associated
R3837 T4863 T4864 arg1Of associated,with
R3838 T4867 T4864 arg2Of domain,with
R3839 T4867 T4865 arg1Of domain,the
R384 T453 T452 arg1Of decrease,time-dependent
R3840 T4867 T4866 arg1Of domain,FKH
R3841 T4868 T4859 arg3Of ),(
R3842 T4870 T4869 arg2Of Foxp3,of
R3843 T4871 T4855 arg2Of was,determine
R3844 T4871 T4856 arg1Of was,whether
R3845 T4873 T4871 arg2Of prerequisite,was
R3846 T4873 T4872 arg1Of prerequisite,a
R3847 T4873 T4874 arg1Of prerequisite,for
R3848 T4875 T4874 arg2Of inhibition,for
R3849 T4875 T4876 arg1Of inhibition,of
R385 T453 T454 arg1Of decrease,in
R3850 T4878 T4876 arg2Of activation,of
R3851 T4878 T4877 arg1Of activation,NF-κB
R3852 T4881 T4880 arg1Of interaction,Foxp3
R3853 T4881 T4882 arg1Of interaction,with
R3854 T4881 T4885 arg1Of interaction,takes
R3855 T4883 T4882 arg2Of NF-κB,with
R3856 T4885 T4879 arg2Of takes,Although
R3857 T4885 T4884 arg1Of takes,presumably
R3858 T4885 T4887 arg1Of takes,in
R3859 T4886 T4885 arg2Of place,takes
R386 T513 T511 arg2Of transcription,suppressed
R3860 T4889 T4887 arg2Of nucleus,in
R3861 T4889 T4888 arg1Of nucleus,the
R3862 T4894 T4879 arg1Of be,Although
R3863 T4894 T4890 arg1Of be,","
R3864 T4894 T4892 arg2Of be,may
R3865 T4894 T4893 arg1Of be,also
R3866 T4895 T4894 arg2Of possible,be
R3867 T4900 T4896 arg1Of protein,for
R3868 T4900 T4897 arg1Of protein,a
R3869 T4900 T4898 arg1Of protein,cytoplasmic
R387 T456 T454 arg2Of levels,in
R3870 T4900 T4899 arg1Of protein,Foxp3
R3871 T4900 T4902 arg1Of protein,bind
R3872 T4900 T4909 arg1Of protein,prevent
R3873 T4902 T4903 arg1Of bind,to
R3874 T4902 T4905 arg1Of bind,in
R3875 T4902 T4908 arg1Of bind,and
R3876 T4904 T4903 arg2Of NF-κB,to
R3877 T4907 T4905 arg2Of cytoplasm,in
R3878 T4907 T4906 arg1Of cytoplasm,the
R3879 T4908 T4891 arg1Of and,it
R388 T456 T455 arg1Of levels,basal
R3880 T4908 T4892 arg1Of and,may
R3881 T4908 T4894 arg1Of and,be
R3882 T4908 T4895 arg1Of and,possible
R3883 T4908 T4896 arg2Of and,for
R3884 T4908 T4901 arg1Of and,to
R3885 T4909 T4908 arg2Of prevent,and
R3886 T4909 T4911 arg1Of prevent,to
R3887 T4909 T4914 arg1Of prevent,following
R3888 T4910 T4909 arg2Of localization,prevent
R3889 T4913 T4911 arg2Of nucleus,to
R389 T456 T457 arg1Of levels,of
R3890 T4913 T4912 arg1Of nucleus,the
R3891 T4917 T4914 arg2Of stimulus,following
R3892 T4917 T4915 arg1Of stimulus,an
R3893 T4917 T4916 arg1Of stimulus,activation
R3894 T4918 T4919 arg1Of Overexpression,of
R3895 T4918 T4925 arg1Of Overexpression,of
R3896 T4918 T4928 arg1Of Overexpression,was
R3897 T4918 T4929 arg1Of Overexpression,able
R3898 T4918 T4931 arg1Of Overexpression,suppress
R3899 T4919 T4923 arg1Of of,but
R390 T513 T512 arg1Of transcription,the
R3900 T4921 T4919 arg2Of Foxp3,of
R3901 T4921 T4920 arg1Of Foxp3,full-length
R3902 T4923 T4922 arg1Of but,","
R3903 T4925 T4923 arg2Of of,but
R3904 T4925 T4924 arg1Of of,not
R3905 T4926 T4925 arg2Of ΔFKH,of
R3906 T4928 T4927 arg1Of was,","
R3907 T4929 T4928 arg2Of able,was
R3908 T4931 T4929 arg2Of suppress,able
R3909 T4931 T4930 arg1Of suppress,to
R391 T513 T514 arg1Of transcription,of
R3910 T4932 T4931 arg2Of activation,suppress
R3911 T4932 T4933 arg1Of activation,of
R3912 T4932 T4939 arg1Of activation,in
R3913 T4938 T4933 arg2Of vector,of
R3914 T4938 T4934 arg1Of vector,a
R3915 T4938 T4935 arg2Of vector,cotransfected
R3916 T4938 T4936 arg1Of vector,NF-κB
R3917 T4938 T4937 arg1Of vector,reporter
R3918 T4942 T4939 arg2Of cells,in
R3919 T4942 T4940 arg1Of cells,HEK
R392 T518 T514 arg2Of promoters,of
R3920 T4942 T4941 arg1Of cells,293T
R3921 T4942 T4943 arg1Of cells,(
R3922 T4945 T4943 arg2Of 2B,(
R3923 T4945 T4944 arg1Of 2B,Figure
R3924 T4946 T4943 arg3Of ),(
R3925 T4948 T4949 arg1Of Foxp3,and
R3926 T4949 T4947 arg1Of and,Both
R3927 T4949 T4951 arg1Of and,were
R3928 T4949 T4952 arg2Of and,expressed
R3929 T4950 T4949 arg2Of ΔFKH,and
R393 T461 T460 arg2Of NF-κB,(
R3930 T4952 T4951 arg2Of expressed,were
R3931 T4952 T4953 arg1Of expressed,at
R3932 T4952 T4957 arg1Of expressed,following
R3933 T4952 T4959 arg1Of expressed,as
R3934 T4955 T4954 arg1Of high,very
R3935 T4956 T4953 arg2Of levels,at
R3936 T4956 T4955 arg1Of levels,high
R3937 T4958 T4957 arg2Of transfection,following
R3938 T4960 T4959 arg2Of detected,as
R3939 T4963 T4960 arg1Of RT-PCR,detected
R394 T462 T460 arg3Of ),(
R3940 T4963 T4961 arg2Of RT-PCR,by
R3941 T4963 T4962 arg1Of RT-PCR,real-time
R3942 T4963 T4964 arg1Of RT-PCR,(
R3943 T4966 T4964 arg2Of data,(
R3944 T4966 T4965 arg1Of data,unpublished
R3945 T4967 T4964 arg3Of ),(
R3946 T4969 T4968 arg1Of data,These
R3947 T4969 T4970 arg1Of data,appear
R3948 T4969 T4972 arg1Of data,suggest
R3949 T4972 T4970 arg2Of suggest,appear
R395 T463 T457 arg2Of activation,of
R3950 T4972 T4971 arg1Of suggest,to
R3951 T4977 T4974 arg1Of domain,the
R3952 T4977 T4975 arg1Of domain,carboxyl-terminal
R3953 T4977 T4976 arg1Of domain,FKH
R3954 T4977 T4978 arg1Of domain,is
R3955 T4977 T4980 arg1Of domain,important
R3956 T4978 T4972 arg2Of is,suggest
R3957 T4978 T4973 arg1Of is,that
R3958 T4978 T4979 arg1Of is,critically
R3959 T4978 T4983 modOf is,to
R396 T463 T458 arg1Of activation,nuclear
R3960 T4980 T4978 arg2Of important,is
R3961 T4980 T4981 arg1Of important,for
R3962 T4982 T4981 arg2Of Foxp3,for
R3963 T4984 T4983 arg1Of down-regulate,to
R3964 T4986 T4984 arg2Of transcription,down-regulate
R3965 T4986 T4985 arg1Of transcription,NF-κB-dependent
R3966 T4990 T4989 arg1Of activation,NF-κB
R3967 T4990 T4991 arg1Of activation,was
R3968 T4990 T4992 arg2Of activation,blocked
R3969 T4992 T4987 arg1Of blocked,However
R397 T463 T459 arg1Of activation,factor-κB
R3970 T4992 T4988 arg1Of blocked,","
R3971 T4992 T4991 arg2Of blocked,was
R3972 T4992 T4993 arg1Of blocked,to
R3973 T4996 T4993 arg2Of extent,to
R3974 T4996 T4994 arg1Of extent,a
R3975 T4996 T4995 arg1Of extent,similar
R3976 T5000 T4999 arg1Of Foxp3,full-length
R3977 T5000 T5001 arg1Of Foxp3,and
R3978 T5001 T4992 arg1Of and,blocked
R3979 T5001 T4997 arg2Of and,by
R398 T463 T460 arg1Of activation,(
R3980 T5001 T4998 arg1Of and,both
R3981 T5001 T5003 arg1Of and,in
R3982 T5002 T5001 arg2Of ΔFKH,and
R3983 T5006 T5004 arg1Of cells,Jurkat
R3984 T5006 T5005 arg1Of cells,T
R3985 T5006 T5007 arg1Of cells,(
R3986 T5006 T5011 arg1Of cells,and
R3987 T5009 T5007 arg2Of 2C,(
R3988 T5009 T5008 arg1Of 2C,Figure
R3989 T5010 T5007 arg3Of ),(
R399 T464 T465 arg1Of Deletion,of
R3990 T5011 T5003 arg2Of and,in
R3991 T5016 T5011 arg2Of cells,and
R3992 T5016 T5012 arg1Of cells,primary
R3993 T5016 T5013 arg1Of cells,human
R3994 T5016 T5014 arg1Of cells,CD4+
R3995 T5016 T5015 arg1Of cells,T
R3996 T5016 T5017 arg1Of cells,(
R3997 T5019 T5017 arg2Of 2D,(
R3998 T5019 T5018 arg1Of 2D,Figure
R3999 T5020 T5017 arg3Of ),(
R400 T464 T482 arg1Of Deletion,abrogated
R4000 T5023 T5021 arg1Of analysis,Western
R4001 T5023 T5022 arg1Of analysis,blot
R4002 T5023 T5024 arg1Of analysis,of
R4003 T5023 T5028 arg1Of analysis,demonstrated
R4004 T5027 T5024 arg2Of expression,of
R4005 T5027 T5025 arg1Of expression,NF-κB
R4006 T5027 T5026 arg1Of expression,p65
R4007 T5030 T5031 arg1Of Foxp3,and
R4008 T5031 T5033 arg1Of and,does
R4009 T5031 T5035 arg1Of and,block
R401 T518 T515 arg1Of promoters,two
R4010 T5032 T5031 arg2Of ΔFKH,and
R4011 T5035 T5028 arg2Of block,demonstrated
R4012 T5035 T5029 arg1Of block,that
R4013 T5035 T5033 arg2Of block,does
R4014 T5035 T5034 arg1Of block,not
R4015 T5035 T5038 arg1Of block,at
R4016 T5037 T5035 arg2Of activation,block
R4017 T5037 T5036 arg1Of activation,NF-κB
R4018 T5040 T5038 arg2Of level,at
R4019 T5040 T5039 arg1Of level,the
R402 T470 T469 arg2Of FKH,(
R4020 T5040 T5041 arg1Of level,of
R4021 T5044 T5041 arg2Of expression,of
R4022 T5044 T5042 arg1Of expression,p65
R4023 T5044 T5043 arg1Of expression,protein
R4024 T5044 T5045 arg1Of expression,(
R4025 T5047 T5045 arg2Of 2E,(
R4026 T5047 T5046 arg1Of 2E,Figure
R4027 T5048 T5045 arg3Of ),(
R4028 T5050 T5049 arg1Of results,These
R4029 T5050 T5051 arg1Of results,are
R403 T471 T469 arg3Of ),(
R4030 T5050 T5053 arg1Of results,interesting
R4031 T5051 T5059 arg1Of are,","
R4032 T5051 T5060 arg1Of are,because
R4033 T5053 T5051 arg2Of interesting,are
R4034 T5053 T5052 arg1Of interesting,very
R4035 T5053 T5054 arg1Of interesting,with
R4036 T5055 T5054 arg2Of respect,with
R4037 T5055 T5056 arg1Of respect,to
R4038 T5058 T5056 arg2Of function,to
R4039 T5058 T5057 arg1Of function,Foxp3
R404 T472 T465 arg2Of domain,of
R4040 T5061 T5062 arg1Of they,suggest
R4041 T5062 T5060 arg2Of suggest,because
R4042 T5067 T5065 arg1Of domain,carboxyl-terminal
R4043 T5067 T5066 arg1Of domain,FKH
R4044 T5067 T5069 arg1Of domain,and
R4045 T5069 T5064 arg1Of and,the
R4046 T5069 T5068 arg1Of and,","
R4047 T5069 T5074 arg1Of and,are
R4048 T5069 T5075 arg1Of and,dispensable
R4049 T5072 T5069 arg2Of localization,and
R405 T472 T466 arg1Of domain,the
R4050 T5072 T5070 arg1Of localization,possibly
R4051 T5072 T5071 arg1Of localization,nuclear
R4052 T5074 T5062 arg2Of are,suggest
R4053 T5074 T5063 arg1Of are,that
R4054 T5074 T5073 arg1Of are,","
R4055 T5075 T5074 arg2Of dispensable,are
R4056 T5075 T5076 arg1Of dispensable,for
R4057 T5078 T5076 arg2Of function,for
R4058 T5078 T5077 arg1Of function,Foxp3
R4059 T5078 T5079 arg1Of function,in
R406 T472 T467 arg1Of domain,carboxyl-terminal
R4060 T5082 T5079 arg2Of populations,in
R4061 T5082 T5080 arg1Of populations,T
R4062 T5082 T5081 arg1Of populations,cell
R4063 T5084 T5083 arg1Of interpretations,Alternative
R4064 T5084 T5085 arg1Of interpretations,may
R4065 T5084 T5086 arg1Of interpretations,include
R4066 T5086 T5085 arg2Of include,may
R4067 T5088 T5086 arg2Of possibility,include
R4068 T5088 T5087 arg1Of possibility,the
R4069 T5091 T5090 arg1Of localization,the
R407 T472 T468 arg1Of domain,forkhead
R4070 T5091 T5092 arg1Of localization,of
R4071 T5091 T5094 arg1Of localization,differ
R4072 T5093 T5092 arg2Of ΔFKH,of
R4073 T5094 T5088 arg2Of differ,possibility
R4074 T5094 T5089 arg1Of differ,that
R4075 T5094 T5095 arg1Of differ,between
R4076 T5097 T5096 arg1Of cells,epithelial
R4077 T5097 T5098 arg1Of cells,and
R4078 T5098 T5095 arg2Of and,between
R4079 T5100 T5098 arg2Of cells,and
R408 T472 T469 arg1Of domain,(
R4080 T5100 T5099 arg1Of cells,T
R4081 T5103 T5101 arg2Of case,In
R4082 T5103 T5102 arg1Of case,either
R4083 T5106 T5105 arg1Of results,these
R4084 T5106 T5107 arg1Of results,suggest
R4085 T5107 T5101 arg1Of suggest,In
R4086 T5107 T5104 arg1Of suggest,","
R4087 T5111 T5107 arg2Of mechanism,suggest
R4088 T5111 T5108 arg1Of mechanism,a
R4089 T5111 T5109 arg1Of mechanism,cell
R409 T472 T473 arg1Of domain,","
R4090 T5111 T5110 arg1Of mechanism,type-specific
R4091 T5111 T5112 arg1Of mechanism,of
R4092 T5111 T5114 arg1Of mechanism,for
R4093 T5113 T5112 arg2Of action,of
R4094 T5117 T5114 arg2Of mutant,for
R4095 T5117 T5115 arg1Of mutant,this
R4096 T5117 T5116 arg1Of mutant,Foxp3
R410 T472 T474 arg1Of domain,critical
R411 T474 T475 arg1Of critical,for
R412 T477 T476 arg1Of localization,nuclear
R413 T477 T478 arg1Of localization,and
R414 T518 T516 arg1Of promoters,human
R415 T478 T475 arg2Of and,for
R416 T518 T517 arg1Of promoters,retroviral
R417 T480 T478 arg2Of activity,and
R418 T480 T479 arg1Of activity,DNA-binding
R419 T518 T519 arg1Of promoters,(
R420 T518 T533 arg1Of promoters,utilizing
R421 T482 T481 arg1Of abrogated,","
R422 T484 T482 arg2Of ability,abrogated
R423 T484 T483 arg1Of ability,the
R424 T484 T485 arg1Of ability,of
R425 T520 T521 arg1Of HIV-1,and
R426 T486 T485 arg2Of Foxp3,of
R427 T486 T487 modOf Foxp3,to
R428 T488 T487 arg1Of suppress,to
R429 T488 T491 arg1Of suppress,in
R430 T488 T498 arg1Of suppress,in
R431 T490 T488 arg2Of activity,suppress
R432 T490 T489 arg1Of activity,NF-κB
R433 T491 T496 arg1Of in,but
R434 T521 T519 arg2Of and,(
R435 T527 T521 arg2Of type,and
R436 T494 T491 arg2Of cells,in
R437 T494 T492 arg1Of cells,HEK
R438 T494 T493 arg1Of cells,293T
R439 T496 T495 arg1Of but,","
R440 T498 T496 arg2Of in,but
R441 T498 T497 arg1Of in,not
R442 T499 T500 arg1Of Jurkat,or
R443 T500 T498 arg2Of or,in
R444 T527 T522 arg1Of type,human
R445 T527 T523 arg1Of type,T
R446 T527 T524 arg1Of type,cell
R447 T527 T525 arg1Of type,lymphotropic
R448 T527 T526 arg1Of type,virus
R449 T527 T528 arg1Of type,I
R450 T527 T529 arg1Of type,[
R451 T530 T529 arg2Of HTLV-I,[
R452 T531 T529 arg3Of ],[
R453 T532 T519 arg3Of ),(
R454 T610 T611 arg1Of cellular,and
R455 T534 T535 arg1Of NF-κB-dependent,and
R456 T612 T611 arg2Of viral,and
R457 T614 T606 arg2Of expression,regulating
R458 T614 T607 arg1Of expression,NF-κB-
R459 T614 T608 arg1Of expression,and
R460 T614 T609 arg1Of expression,CREB-dependent
R461 T614 T610 arg1Of expression,cellular
R462 T614 T612 arg1Of expression,viral
R463 T614 T613 arg1Of expression,gene
R464 T536 T535 arg2Of NF-κB-independent,and
R465 T537 T533 arg2Of mechanisms,utilizing
R466 T537 T534 arg1Of mechanisms,NF-κB-dependent
R467 T537 T536 arg1Of mechanisms,NF-κB-independent
R468 T538 T539 arg1Of Examination,of
R469 T538 T542 arg1Of Examination,identified
R4690 T6003 T6004 arg1Of Foxp3,Suppresses
R4691 T6004 T6008 arg1Of Suppresses,in
R4692 T6004 T6010 arg1Of Suppresses,through
R4693 T6007 T6004 arg2Of Expression,Suppresses
R4694 T6007 T6005 arg1Of Expression,HIV-1
R4695 T6007 T6006 arg1Of Expression,Gene
R4696 T6009 T6008 arg2Of Part,in
R4697 T6011 T6010 arg2Of Blocking,through
R4698 T6012 T6011 arg2Of Activation,Blocking
R4699 T6012 T6013 arg1Of Activation,of
R470 T541 T539 arg2Of latter,of
R4700 T6014 T6013 arg2Of NF-κB,of
R4701 T6016 T6017 arg1Of Foxp3,functions
R4702 T6017 T6015 arg2Of functions,If
R4703 T6017 T6018 arg1Of functions,as
R4704 T6020 T6018 arg2Of repressor,as
R4705 T6020 T6019 arg1Of repressor,a
R4706 T6020 T6021 arg1Of repressor,of
R4707 T6024 T6021 arg2Of expression,of
R4708 T6024 T6022 arg1Of expression,NF-κB-dependent
R4709 T6024 T6023 arg1Of expression,gene
R471 T541 T540 arg1Of latter,the
R4710 T6027 T6028 arg1Of we,hypothesized
R4711 T6028 T6015 arg1Of hypothesized,If
R4712 T6028 T6025 arg1Of hypothesized,","
R4713 T6028 T6026 arg1Of hypothesized,then
R4714 T6031 T6030 arg1Of overexpression,Foxp3
R4715 T6031 T6032 arg1Of overexpression,could
R4716 T6031 T6034 arg1Of overexpression,down-regulate
R4717 T6034 T6028 arg2Of down-regulate,hypothesized
R4718 T6034 T6029 arg1Of down-regulate,that
R4719 T6034 T6032 arg2Of down-regulate,could
R472 T542 T552 arg1Of identified,as
R4720 T6034 T6033 arg1Of down-regulate,selectively
R4721 T6035 T6034 arg2Of transcription,down-regulate
R4722 T6035 T6036 arg1Of transcription,from
R4723 T6037 T6036 arg2Of promoters,from
R4724 T6037 T6039 arg2Of promoters,shown
R4725 T6037 T6041 arg1Of promoters,be
R4726 T6037 T6042 arg1Of promoters,responsive
R4727 T6039 T6038 arg1Of shown,previously
R4728 T6041 T6039 arg3Of be,shown
R4729 T6041 T6040 arg1Of be,to
R473 T549 T548 arg2Of CREB,(
R4730 T6042 T6041 arg2Of responsive,be
R4731 T6042 T6043 arg1Of responsive,to
R4732 T6044 T6043 arg2Of NF-κB,to
R4733 T6046 T6045 arg1Of address,To
R4734 T6048 T6046 arg2Of question,address
R4735 T6048 T6047 arg1Of question,this
R4736 T6050 T6046 arg1Of we,address
R4737 T6050 T6051 arg1Of we,examined
R4738 T6051 T6045 modOf examined,To
R4739 T6051 T6049 arg1Of examined,","
R474 T550 T548 arg3Of ),(
R4740 T6054 T6051 arg2Of activation,examined
R4741 T6054 T6052 arg1Of activation,the
R4742 T6054 T6053 arg1Of activation,transcriptional
R4743 T6054 T6055 arg1Of activation,of
R4744 T6054 T6059 arg1Of activation,","
R4745 T6054 T6060 arg1Of activation,which
R4746 T6054 T6061 arg1Of activation,contains
R4747 T6058 T6055 arg2Of LTR,of
R4748 T6058 T6056 arg1Of LTR,the
R4749 T6058 T6057 arg1Of LTR,HIV-1
R475 T551 T542 arg2Of pathway,identified
R4750 T6061 T6074 arg1Of contains,with
R4751 T6061 T6081 arg1Of contains,[
R4752 T6067 T6061 arg2Of sites,contains
R4753 T6067 T6062 arg1Of sites,two
R4754 T6067 T6063 arg1Of sites,tandem
R4755 T6067 T6064 arg1Of sites,cis-acting
R4756 T6067 T6065 arg1Of sites,NF-κB
R4757 T6067 T6066 arg1Of sites,binding
R4758 T6067 T6068 arg1Of sites,located
R4759 T6068 T6069 arg1Of located,between
R476 T551 T543 arg1Of pathway,the
R4760 T6071 T6072 arg1Of −102,and
R4761 T6072 T6069 arg2Of and,between
R4762 T6072 T6070 arg1Of and,positions
R4763 T6073 T6072 arg2Of −81,and
R4764 T6074 T6076 arg1Of with,to
R4765 T6075 T6074 arg2Of respect,with
R4766 T6080 T6074 arg3Of site,with
R4767 T6080 T6077 arg1Of site,the
R4768 T6080 T6078 arg1Of site,transcription
R4769 T6080 T6079 arg1Of site,initiation
R477 T551 T544 arg1Of pathway,cAMP-responsive
R4770 T6082 T6081 arg2Of 21,[
R4771 T6083 T6081 arg3Of ],[
R4772 T6084 T6085 arg1Of NF-κB,plays
R4773 T6085 T6089 arg1Of plays,in
R4774 T6088 T6085 arg2Of role,plays
R4775 T6088 T6086 arg1Of role,a
R4776 T6088 T6087 arg1Of role,crucial
R4777 T6090 T6089 arg2Of regulating,in
R4778 T6092 T6090 arg2Of expression,regulating
R4779 T6092 T6091 arg1Of expression,gene
R478 T551 T545 arg1Of pathway,element
R4780 T6092 T6093 arg2Of expression,directed
R4781 T6093 T6094 arg1Of directed,from
R4782 T6093 T6098 arg1Of directed,in
R4783 T6093 T6102 arg1Of directed,[
R4784 T6097 T6094 arg2Of LTR,from
R4785 T6097 T6095 arg1Of LTR,the
R4786 T6097 T6096 arg1Of LTR,HIV-1
R4787 T6101 T6098 arg2Of cells,in
R4788 T6101 T6099 arg1Of cells,CD4+
R4789 T6101 T6100 arg1Of cells,T
R479 T551 T546 arg1Of pathway,binding
R4790 T6103 T6102 arg2Of 21,[
R4791 T6104 T6102 arg3Of ],[
R4792 T6105 T6106 arg1Of Overexpression,of
R4793 T6105 T6113 arg1Of Overexpression,","
R4794 T6105 T6114 arg1Of Overexpression,in
R4795 T6105 T6118 arg1Of Overexpression,was
R4796 T6105 T6119 arg1Of Overexpression,able
R4797 T6105 T6121 arg1Of Overexpression,inhibit
R4798 T6108 T6107 arg1Of Foxp3,full-length
R4799 T6108 T6110 arg1Of Foxp3,but
R480 T551 T547 arg1Of pathway,protein
R4800 T6110 T6106 arg2Of but,of
R4801 T6110 T6109 arg1Of but,","
R4802 T6110 T6111 arg1Of but,not
R4803 T6112 T6110 arg2Of ΔFKH,but
R4804 T6117 T6114 arg2Of cells,in
R4805 T6117 T6115 arg1Of cells,HEK
R4806 T6117 T6116 arg1Of cells,293T
R4807 T6119 T6118 arg2Of able,was
R4808 T6121 T6119 arg2Of inhibit,able
R4809 T6121 T6120 arg1Of inhibit,to
R481 T551 T548 arg1Of pathway,(
R4810 T6123 T6121 arg2Of activation,inhibit
R4811 T6123 T6122 arg1Of activation,basal
R4812 T6123 T6124 arg1Of activation,of
R4813 T6127 T6124 arg2Of LTR,of
R4814 T6127 T6125 arg1Of LTR,the
R4815 T6127 T6126 arg1Of LTR,HIV-1
R4816 T6127 T6128 arg1Of LTR,(
R4817 T6127 T6132 arg1Of LTR,","
R4818 T6127 T6133 arg1Of LTR,similar
R4819 T6130 T6128 arg2Of 3A,(
R482 T554 T552 arg2Of target,as
R4820 T6130 T6129 arg1Of 3A,Figure
R4821 T6131 T6128 arg3Of ),(
R4822 T6133 T6134 arg1Of similar,to
R4823 T6135 T6134 arg2Of what,to
R4824 T6135 T6136 arg1Of what,was
R4825 T6135 T6138 arg2Of what,demonstrated
R4826 T6138 T6136 arg2Of demonstrated,was
R4827 T6138 T6137 arg1Of demonstrated,previously
R4828 T6138 T6139 arg1Of demonstrated,with
R4829 T6144 T6139 arg2Of vector,with
R483 T554 T553 arg1Of target,a
R4830 T6144 T6140 arg1Of vector,the
R4831 T6144 T6141 arg1Of vector,synthetic
R4832 T6144 T6142 arg1Of vector,NF-κB
R4833 T6144 T6143 arg1Of vector,reporter
R4834 T6144 T6145 arg1Of vector,(
R4835 T6147 T6145 arg2Of 2B,(
R4836 T6147 T6146 arg1Of 2B,Figure
R4837 T6148 T6145 arg3Of ),(
R4838 T6153 T6151 arg1Of activation,HIV-1
R4839 T6153 T6152 arg1Of activation,LTR
R484 T554 T555 arg1Of target,of
R4840 T6153 T6154 arg1Of activation,was
R4841 T6153 T6155 arg2Of activation,suppressed
R4842 T6155 T6149 arg1Of suppressed,Furthermore
R4843 T6155 T6150 arg1Of suppressed,","
R4844 T6155 T6154 arg2Of suppressed,was
R4845 T6158 T6159 arg1Of Foxp3,and
R4846 T6159 T6155 arg1Of and,suppressed
R4847 T6159 T6156 arg2Of and,by
R4848 T6159 T6157 arg1Of and,full-length
R4849 T6159 T6161 arg1Of and,in
R485 T556 T555 arg2Of Foxp3,of
R4850 T6160 T6159 arg2Of ΔFKH,and
R4851 T6164 T6161 arg2Of cells,in
R4852 T6164 T6162 arg1Of cells,Jurkat
R4853 T6164 T6163 arg1Of cells,T
R4854 T6164 T6165 arg1Of cells,(
R4855 T6167 T6165 arg2Of 3B,(
R4856 T6167 T6166 arg1Of 3B,Figure
R4857 T6168 T6165 arg3Of ),(
R4858 T6170 T6169 arg1Of demonstrate,To
R4859 T6175 T6172 arg1Of repression,Foxp3-mediated
R486 T559 T560 arg1Of comparison,of
R4860 T6175 T6173 arg1Of repression,HIV-1
R4861 T6175 T6174 arg1Of repression,LTR
R4862 T6175 T6176 arg1Of repression,was
R4863 T6175 T6177 arg2Of repression,associated
R4864 T6177 T6170 arg2Of associated,demonstrate
R4865 T6177 T6171 arg1Of associated,that
R4866 T6177 T6176 arg2Of associated,was
R4867 T6177 T6178 arg1Of associated,with
R4868 T6177 T6183 arg1Of associated,to
R4869 T6179 T6178 arg2Of interactions,with
R487 T559 T566 arg1Of comparison,to
R4870 T6179 T6180 arg1Of interactions,with
R4871 T6179 T6182 arg2Of interactions,bound
R4872 T6181 T6180 arg2Of NF-κB,with
R4873 T6186 T6183 arg2Of LTR,to
R4874 T6186 T6184 arg1Of LTR,the
R4875 T6186 T6185 arg1Of LTR,HIV-1
R4876 T6188 T6170 arg1Of we,demonstrate
R4877 T6188 T6189 arg1Of we,compared
R4878 T6189 T6169 modOf compared,To
R4879 T6189 T6187 arg1Of compared,","
R488 T559 T571 arg1Of comparison,in
R4880 T6191 T6190 arg1Of activation,basal
R4881 T6191 T6192 arg1Of activation,of
R4882 T6191 T6196 arg1Of activation,or
R4883 T6195 T6192 arg2Of LTR,of
R4884 T6195 T6193 arg1Of LTR,the
R4885 T6195 T6194 arg1Of LTR,HIV-1
R4886 T6196 T6189 arg2Of or,compared
R4887 T6200 T6196 arg2Of LTR,or
R4888 T6200 T6197 arg1Of LTR,an
R4889 T6200 T6198 arg1Of LTR,identical
R489 T559 T582 arg1Of comparison,suggested
R4890 T6200 T6199 arg1Of LTR,HIV-1
R4891 T6200 T6201 arg1Of LTR,lacking
R4892 T6204 T6201 arg2Of sites,lacking
R4893 T6204 T6202 arg1Of sites,the
R4894 T6204 T6203 arg1Of sites,NF-κB
R4895 T6204 T6205 arg1Of sites,located
R4896 T6205 T6206 arg1Of located,between
R4897 T6207 T6208 arg1Of −102,and
R4898 T6208 T6206 arg2Of and,between
R4899 T6208 T6210 arg1Of and,(
R490 T565 T560 arg2Of cells,of
R4900 T6208 T6215 arg1Of and,(
R4901 T6209 T6208 arg2Of −81,and
R4902 T6213 T6210 arg2Of LTR,(
R4903 T6213 T6211 arg1Of LTR,HIV-1
R4904 T6213 T6212 arg1Of LTR,Δ-κB
R4905 T6214 T6210 arg3Of ),(
R4906 T6217 T6215 arg2Of 3C,(
R4907 T6217 T6216 arg1Of 3C,Figure
R4908 T6218 T6215 arg3Of ),(
R4909 T6223 T6219 arg1Of construct,This
R491 T565 T561 arg1Of cells,the
R4910 T6223 T6220 arg1Of construct,mutant
R4911 T6223 T6221 arg1Of construct,HIV-1
R4912 T6223 T6222 arg1Of construct,LTR
R4913 T6223 T6224 arg1Of construct,exhibited
R4914 T6224 T6229 arg1Of exhibited,compared
R4915 T6226 T6224 arg2Of levels,exhibited
R4916 T6226 T6225 arg2Of levels,reduced
R4917 T6226 T6227 arg1Of levels,of
R4918 T6228 T6227 arg2Of transcription,of
R4919 T6230 T6229 arg2Of to,compared
R492 T565 T562 arg1Of cells,percent
R4920 T6234 T6230 arg2Of LTR,to
R4921 T6234 T6231 arg1Of LTR,the
R4922 T6234 T6232 arg1Of LTR,parental
R4923 T6234 T6233 arg1Of LTR,HIV-1
R4924 T6234 T6235 arg1Of LTR,in
R4925 T6241 T6235 arg2Of cells,in
R4926 T6241 T6236 arg2Of cells,purified
R4927 T6241 T6237 arg1Of cells,healthy
R4928 T6241 T6238 arg1Of cells,donor
R4929 T6241 T6239 arg1Of cells,CD4+
R4930 T6241 T6240 arg1Of cells,T
R4931 T6241 T6242 arg1Of cells,(
R4932 T6244 T6242 arg2Of data,(
R4933 T6244 T6243 arg1Of data,unpublished
R4934 T6245 T6242 arg3Of ),(
R4935 T6249 T6263 arg1Of comparing,demonstrated
R4936 T6251 T6249 arg2Of effect,comparing
R4937 T6251 T6250 arg1Of effect,the
R4938 T6251 T6252 arg1Of effect,of
R4939 T6251 T6255 arg1Of effect,on
R4940 T6254 T6252 arg2Of overexpression,of
R4941 T6254 T6253 arg1Of overexpression,Foxp3
R4942 T6257 T6255 arg2Of activation,on
R4943 T6257 T6256 arg1Of activation,the
R4944 T6257 T6258 arg1Of activation,of
R4945 T6262 T6258 arg2Of promoters,of
R4946 T6262 T6259 arg1Of promoters,these
R4947 T6262 T6260 arg1Of promoters,two
R4948 T6262 T6261 arg1Of promoters,viral
R4949 T6263 T6246 arg1Of demonstrated,However
R495 T565 T563 arg1Of cells,Foxp3+CD4+CD25+
R4950 T6263 T6247 arg1Of demonstrated,","
R4951 T6263 T6248 arg1Of demonstrated,directly
R4952 T6265 T6266 arg1Of Foxp3,was
R4953 T6265 T6268 arg1Of Foxp3,capable
R4954 T6265 T6270 arg1Of Foxp3,suppressing
R4955 T6266 T6263 arg2Of was,demonstrated
R4956 T6266 T6264 arg1Of was,that
R4957 T6268 T6266 arg2Of capable,was
R4958 T6268 T6267 arg1Of capable,more
R4959 T6268 T6269 arg1Of capable,of
R496 T565 T564 arg1Of cells,T
R4960 T6270 T6269 arg2Of suppressing,of
R4961 T6270 T6281 arg1Of suppressing,compared
R4962 T6272 T6270 arg2Of activation,suppressing
R4963 T6272 T6271 arg1Of activation,transcriptional
R4964 T6272 T6273 arg1Of activation,of
R4965 T6276 T6273 arg2Of LTR,of
R4966 T6276 T6274 arg1Of LTR,the
R4967 T6276 T6275 arg1Of LTR,HIV-1
R4968 T6276 T6277 arg1Of LTR,(
R4969 T6279 T6277 arg2Of 3D,(
R497 T570 T566 arg2Of load,to
R4970 T6279 T6278 arg1Of 3D,Figure
R4971 T6280 T6277 arg3Of ),(
R4972 T6282 T6281 arg2Of to,compared
R4973 T6286 T6282 arg2Of LTR,to
R4974 T6286 T6283 arg1Of LTR,the
R4975 T6286 T6284 arg2Of LTR,mutated
R4976 T6286 T6285 arg1Of LTR,HIV-1
R4977 T6286 T6287 arg1Of LTR,(
R4978 T6289 T6287 arg2Of 3E,(
R4979 T6289 T6288 arg1Of 3E,Figure
R4980 T6290 T6287 arg3Of ),(
R4981 T6292 T6291 arg1Of results,These
R4982 T6292 T6293 arg1Of results,suggest
R4983 T6296 T6295 arg1Of down-regulation,Foxp3
R4984 T6296 T6297 arg1Of down-regulation,of
R4985 T6296 T6301 arg1Of down-regulation,was
R4986 T6296 T6302 arg2Of down-regulation,mediated
R4987 T6300 T6297 arg2Of activation,of
R4988 T6300 T6298 arg1Of activation,HIV-1
R4989 T6300 T6299 arg1Of activation,LTR
R4990 T6302 T6293 arg2Of mediated,suggest
R4991 T6302 T6294 arg1Of mediated,that
R4992 T6302 T6301 arg2Of mediated,was
R4993 T6302 T6305 arg1Of mediated,in
R4994 T6304 T6303 arg1Of least,at
R4995 T6305 T6304 arg1Of in,least
R4996 T6306 T6305 arg2Of part,in
R4997 T6311 T6302 arg1Of sites,mediated
R4998 T6311 T6307 arg2Of sites,by
R4999 T6311 T6308 arg1Of sites,cis-acting
R500 T570 T567 arg1Of load,the
R5000 T6311 T6309 arg1Of sites,NF-κB
R5001 T6311 T6310 arg1Of sites,binding
R5002 T6313 T6312 arg1Of levels,Residual
R5003 T6313 T6314 arg1Of levels,of
R5004 T6313 T6323 arg1Of levels,may
R5005 T6313 T6324 arg1Of levels,be
R5006 T6313 T6325 arg1Of levels,due
R5007 T6315 T6314 arg2Of inhibition,of
R5008 T6315 T6316 arg1Of inhibition,of
R5009 T6315 T6321 arg1Of inhibition,by
R501 T570 T568 arg1Of load,HTLV-I
R5010 T6320 T6316 arg2Of LTR,of
R5011 T6320 T6317 arg1Of LTR,the
R5012 T6320 T6318 arg1Of LTR,HIV-1
R5013 T6320 T6319 arg1Of LTR,Δ-κB
R5014 T6322 T6321 arg2Of Foxp3,by
R5015 T6324 T6323 arg2Of be,may
R5016 T6324 T6340 arg1Of be,[
R5017 T6325 T6324 arg2Of due,be
R5018 T6325 T6326 arg1Of due,to
R5019 T6325 T6331 arg1Of due,upstream
R502 T570 T569 arg1Of load,proviral
R5020 T6329 T6326 arg2Of sites,to
R5021 T6329 T6327 arg1Of sites,NF-AT
R5022 T6329 T6328 arg1Of sites,binding
R5023 T6329 T6330 arg1Of sites,located
R5024 T6331 T6332 arg1Of upstream,of
R5025 T6335 T6332 arg2Of sites,of
R5026 T6335 T6333 arg1Of sites,the
R5027 T6335 T6334 arg1Of sites,NF-κB
R5028 T6335 T6336 arg1Of sites,within
R5029 T6339 T6336 arg2Of LTR,within
R503 T574 T572 arg1Of carriers,HTLV-I-infected
R5030 T6339 T6337 arg1Of LTR,the
R5031 T6339 T6338 arg1Of LTR,HIV-1
R5032 T6341 T6340 arg2Of "22,23",[
R5033 T6342 T6340 arg3Of ],[
R505 T574 T573 arg1Of carriers,asymptomatic
R507 T574 T575 arg1Of carriers,and
R515 T575 T571 arg2Of and,in
R518 T576 T575 arg2Of patients,and
R521 T576 T577 arg1Of patients,with
R522 T580 T578 arg1Of spastic,HTLV-I-associated
R528 T580 T579 arg1Of spastic,myelopathy/tropical
R530 T581 T577 arg2Of paraparesis,with
R532 T581 T580 arg1Of paraparesis,spastic
R534 T582 T557 arg1Of suggested,Finally
R535 T582 T558 arg1Of suggested,","
R536 T586 T584 arg1Of expression,high
R542 T586 T585 arg1Of expression,Foxp3
R544 T586 T587 arg1Of expression,is
R545 T586 T588 arg2Of expression,associated
R546 T588 T582 arg2Of associated,suggested
R547 T588 T583 arg1Of associated,that
R548 T588 T587 arg2Of associated,is
R549 T588 T589 arg1Of associated,with
R550 T592 T590 arg1Of load,low
R553 T592 T591 arg1Of load,proviral
R555 T592 T593 arg1Of load,and
R556 T593 T589 arg2Of and,with
R557 T594 T593 arg2Of absence,and
R559 T594 T595 arg1Of absence,of
R560 T596 T595 arg2Of disease,of
R561 T598 T597 arg1Of results,These
R562 T598 T599 arg1Of results,suggest
R563 T602 T599 arg2Of role,suggest
R571 T602 T600 arg1Of role,an
R573 T602 T601 arg2Of role,expanded
R576 T602 T603 arg1Of role,for
R578 T602 T605 arg1Of role,in
R579 T606 T605 arg2Of regulating,in
R5888 T7544 T7548 arg1Of Functions,Are
R5889 T7544 T7549 arg2Of Functions,Suppressed
R5890 T7544 T7542 arg1Of Functions,The
R5891 T7544 T7543 arg1Of Functions,Transactivation
R5892 T7544 T7545 arg1Of Functions,of
R5893 T7547 T7545 arg2Of Tax,of
R5894 T7547 T7546 arg1Of Tax,HTLV-I
R5895 T7549 T7548 arg2Of Suppressed,Are
R5896 T7551 T7549 arg1Of Foxp3,Suppressed
R5897 T7551 T7550 arg2Of Foxp3,by
R5898 T7553 T7552 arg1Of studies,Previous
R5899 T7553 T7554 arg1Of studies,by
R5900 T7553 T7558 arg1Of studies,have
R5901 T7553 T7559 arg1Of studies,demonstrated
R5902 T7555 T7556 arg1Of Bettelli,and
R5903 T7556 T7554 arg2Of and,by
R5904 T7557 T7556 arg2Of colleagues,and
R5905 T7559 T7558 arg2Of demonstrated,have
R5906 T7561 T7562 arg1Of Foxp3,can
R5907 T7561 T7563 arg1Of Foxp3,repress
R5908 T7563 T7559 arg2Of repress,demonstrated
R5909 T7563 T7560 arg1Of repress,that
R5910 T7563 T7562 arg2Of repress,can
R5911 T7563 T7579 arg1Of repress,[
R5912 T7567 T7566 arg1Of levels,basal
R5913 T7567 T7568 arg1Of levels,of
R5914 T7567 T7573 arg1Of levels,as
R5915 T7570 T7568 arg2Of activation,of
R5916 T7570 T7569 arg1Of activation,NF-κB
R5917 T7573 T7563 arg2Of as,repress
R5918 T7573 T7564 arg1Of as,both
R5919 T7573 T7565 arg1Of as,the
R5920 T7573 T7571 arg1Of as,as
R5921 T7573 T7572 arg1Of as,well
R5922 T7576 T7574 arg1Of factor-α-stimulated,tumor
R5923 T7576 T7575 arg1Of factor-α-stimulated,necrosis
R5924 T7578 T7573 arg2Of activation,as
R5925 T7578 T7576 arg1Of activation,factor-α-stimulated
R5926 T7578 T7577 arg1Of activation,NF-κB
R5927 T7580 T7579 arg2Of 15,[
R5928 T7581 T7579 arg3Of ],[
R5929 T7584 T7582 arg1Of step,Our
R5930 T7584 T7583 arg1Of step,next
R5931 T7584 T7585 arg1Of step,was
R5932 T7587 T7585 arg2Of determine,was
R5933 T7587 T7586 arg1Of determine,to
R5934 T7589 T7590 arg1Of Foxp3,could
R5935 T7589 T7592 arg1Of Foxp3,suppress
R5936 T7592 T7587 arg2Of suppress,determine
R5937 T7592 T7588 arg1Of suppress,whether
R5938 T7592 T7590 arg2Of suppress,could
R5939 T7592 T7591 arg1Of suppress,also
R5940 T7594 T7592 arg2Of activation,suppress
R5941 T7594 T7593 arg1Of activation,the
R5942 T7594 T7595 arg1Of activation,of
R5943 T7596 T7595 arg2Of NF-κB,of
R5944 T7596 T7597 arg2Of NF-κB,caused
R5945 T7603 T7597 arg1Of protein,caused
R5946 T7603 T7598 arg2Of protein,by
R5947 T7603 T7599 arg1Of protein,a
R5948 T7603 T7600 arg1Of protein,strong
R5949 T7603 T7601 arg1Of protein,viral
R5950 T7603 T7602 arg1Of protein,transactivator
R5951 T7604 T7605 arg1Of HTLV-I,encodes
R5952 T7609 T7605 arg2Of protein,encodes
R5953 T7609 T7606 arg1Of protein,a
R5954 T7609 T7607 arg1Of protein,multifunctional
R5955 T7609 T7608 arg1Of protein,transactivator
R5956 T7609 T7610 arg1Of protein,","
R5957 T7609 T7612 arg1Of protein,","
R5958 T7609 T7613 arg1Of protein,capable
R5959 T7611 T7610 arg2Of Tax,","
R5960 T7613 T7614 arg1Of capable,of
R5961 T7615 T7614 arg2Of activating,of
R5962 T7618 T7619 arg1Of NF-κB,and
R5963 T7620 T7619 arg2Of CREB,and
R5964 T7621 T7615 arg2Of pathways,activating
R5965 T7621 T7616 arg1Of pathways,both
R5966 T7621 T7617 arg1Of pathways,the
R5967 T7621 T7618 arg1Of pathways,NF-κB
R5968 T7621 T7620 arg1Of pathways,CREB
R5969 T7621 T7622 arg1Of pathways,[
R5970 T7623 T7622 arg2Of 24–29,[
R5971 T7624 T7622 arg3Of ],[
R5972 T7629 T7626 arg1Of protein,the
R5973 T7629 T7627 arg1Of protein,HTLV-I
R5974 T7629 T7628 arg1Of protein,Tax
R5975 T7629 T7630 arg1Of protein,can
R5976 T7629 T7631 arg1Of protein,function
R5977 T7631 T7625 arg2Of function,Since
R5978 T7631 T7630 arg2Of function,can
R5979 T7631 T7632 arg1Of function,at
R5980 T7631 T7635 arg1Of function,in
R5981 T7631 T7642 modOf function,to
R5982 T7634 T7632 arg2Of levels,at
R5983 T7634 T7633 arg1Of levels,multiple
R5984 T7638 T7637 arg1Of cytoplasm,the
R5985 T7638 T7639 arg1Of cytoplasm,and
R5986 T7639 T7635 arg2Of and,in
R5987 T7639 T7636 arg1Of and,both
R5988 T7641 T7639 arg2Of nucleus,and
R5989 T7641 T7640 arg1Of nucleus,the
R5990 T7643 T7642 arg1Of stimulate,to
R5991 T7643 T7647 arg1Of stimulate,[
R5992 T7644 T7643 arg2Of activation,stimulate
R5993 T7644 T7645 arg1Of activation,of
R5994 T7646 T7645 arg2Of NF-κB,of
R5995 T7648 T7647 arg2Of "28,29",[
R5996 T7649 T7647 arg3Of ],[
R5997 T7651 T7652 arg1Of we,hypothesized
R5998 T7652 T7625 arg1Of hypothesized,Since
R5999 T7652 T7650 arg1Of hypothesized,","
R6000 T7654 T7655 arg1Of overexpression,of
R6001 T7654 T7657 arg1Of overexpression,may
R6002 T7654 T7658 arg1Of overexpression,interfere
R6003 T7656 T7655 arg2Of Foxp3,of
R6004 T7658 T7652 arg2Of interfere,hypothesized
R6005 T7658 T7653 arg1Of interfere,that
R6006 T7658 T7657 arg2Of interfere,may
R6007 T7658 T7659 arg1Of interfere,with
R6008 T7661 T7659 arg2Of process,with
R6009 T7661 T7660 arg1Of process,this
R6010 T7668 T7665 arg1Of expression,Tax-dependent
R6011 T7668 T7666 arg1Of expression,HTLV-I
R6012 T7668 T7667 arg1Of expression,gene
R6013 T7668 T7669 arg1Of expression,is
R6014 T7668 T7670 arg1Of expression,independent
R6015 T7669 T7664 arg2Of is,since
R6016 T7669 T7673 arg1Of is,[
R6017 T7670 T7669 arg2Of independent,is
R6018 T7670 T7671 arg1Of independent,of
R6019 T7672 T7671 arg2Of NF-κB,of
R6020 T7674 T7673 arg2Of 18,[
R6021 T7675 T7673 arg3Of ],[
R6022 T7677 T7679 arg1Of we,hypothesized
R6023 T7679 T7662 arg1Of hypothesized,However
R6024 T7679 T7663 arg1Of hypothesized,","
R6025 T7679 T7664 arg1Of hypothesized,since
R6026 T7679 T7676 arg1Of hypothesized,","
R6027 T7679 T7678 arg1Of hypothesized,also
R6028 T7681 T7682 arg1Of Foxp3,would
R6029 T7681 T7684 arg1Of Foxp3,affect
R6030 T7684 T7679 arg2Of affect,hypothesized
R6031 T7684 T7680 arg1Of affect,that
R6032 T7684 T7682 arg2Of affect,would
R6033 T7684 T7683 arg1Of affect,not
R6034 T7686 T7684 arg2Of activation,affect
R6035 T7686 T7685 arg1Of activation,Tax-dependent
R6036 T7686 T7687 arg1Of activation,of
R6037 T7690 T7687 arg2Of LTR,of
R6038 T7690 T7688 arg1Of LTR,the
R6039 T7690 T7689 arg1Of LTR,HTLV-I
R6040 T7692 T7691 arg1Of test,To
R6041 T7694 T7692 arg2Of hypotheses,test
R6042 T7694 T7693 arg1Of hypotheses,these
R6043 T7696 T7692 arg1Of we,test
R6044 T7696 T7697 arg1Of we,overexpressed
R6045 T7697 T7691 modOf overexpressed,To
R6046 T7697 T7695 arg1Of overexpressed,","
R6047 T7699 T7698 arg1Of Tax,HTLV-I
R6048 T7699 T7700 arg1Of Tax,","
R6049 T7700 T7704 arg1Of ",",and/or
R6050 T7702 T7700 arg2Of Foxp3,","
R6051 T7702 T7701 arg1Of Foxp3,full-length
R6052 T7704 T7697 arg2Of and/or,overexpressed
R6053 T7704 T7703 arg1Of and/or,","
R6054 T7704 T7706 arg1Of and/or,in
R6055 T7705 T7704 arg2Of ΔFKH,and/or
R6056 T7709 T7706 arg2Of cells,in
R6057 T7709 T7707 arg1Of cells,HEK
R6058 T7709 T7708 arg1Of cells,293T
R6059 T7709 T7710 arg2Of cells,cotransfected
R6060 T7710 T7711 arg1Of cotransfected,with
R6061 T7714 T7715 arg1Of LTR,or
R6062 T7716 T7715 arg2Of NF-κB,or
R6063 T7718 T7711 arg2Of vector,with
R6064 T7718 T7712 arg1Of vector,an
R6065 T7718 T7713 arg1Of vector,HTLV-I
R6066 T7718 T7714 arg1Of vector,LTR
R6067 T7718 T7716 arg1Of vector,NF-κB
R6068 T7718 T7717 arg1Of vector,reporter
R6069 T7720 T7719 arg2Of shown,As
R6070 T7720 T7721 arg1Of shown,in
R6071 T7723 T7721 arg2Of 4A,in
R6072 T7723 T7722 arg1Of 4A,Figure
R6073 T7726 T7725 arg1Of Tax,HTLV-I
R6074 T7726 T7728 arg1Of Tax,up-regulated
R6075 T7728 T7719 arg1Of up-regulated,As
R6076 T7728 T7724 arg1Of up-regulated,","
R6077 T7728 T7727 arg1Of up-regulated,strongly
R6078 T7731 T7728 arg2Of activation,up-regulated
R6079 T7731 T7729 arg1Of activation,NF-κB-dependent
R6080 T7731 T7730 arg1Of activation,transcriptional
R6081 T7731 T7732 arg1Of activation,(
R6082 T7733 T7732 arg2Of ~60-fold,(
R6083 T7734 T7732 arg3Of ),(
R6084 T7737 T7738 arg1Of overexpression,of
R6085 T7737 T7745 arg1Of overexpression,suppressed
R6086 T7739 T7741 arg1Of Foxp3,but
R6087 T7741 T7738 arg2Of but,of
R6088 T7741 T7740 arg1Of but,","
R6089 T7741 T7742 arg1Of but,not
R6090 T7743 T7741 arg2Of ΔFKH,but
R6091 T7745 T7735 arg1Of suppressed,Interestingly
R6092 T7745 T7736 arg1Of suppressed,","
R6093 T7745 T7744 arg1Of suppressed,","
R6094 T7747 T7745 arg2Of activation,suppressed
R6095 T7747 T7746 arg1Of activation,Tax-mediated
R6096 T7747 T7748 arg1Of activation,of
R6097 T7750 T7748 arg2Of transcription,of
R6098 T7750 T7749 arg1Of transcription,NF-κB-dependent
R6099 T7752 T7751 arg1Of observations,These
R6100 T7752 T7754 arg1Of observations,suggest
R6101 T7754 T7753 arg1Of suggest,further
R6102 T7759 T7756 arg1Of domain,the
R6103 T7759 T7757 arg1Of domain,carboxyl-terminal
R6104 T7759 T7758 arg1Of domain,FKH
R6105 T7759 T7760 arg1Of domain,is
R6106 T7759 T7761 arg2Of domain,required
R6107 T7761 T7754 arg2Of required,suggest
R6108 T7761 T7755 arg1Of required,that
R6109 T7761 T7760 arg2Of required,is
R6110 T7761 T7762 arg1Of required,for
R6111 T7763 T7762 arg2Of inhibiting,for
R6112 T7764 T7763 arg2Of activation,inhibiting
R6113 T7764 T7765 arg1Of activation,of
R6114 T7766 T7765 arg2Of NF-κB,of
R6115 T7766 T7767 arg1Of NF-κB,in
R6116 T7769 T7767 arg2Of presence,in
R6117 T7769 T7768 arg1Of presence,the
R6118 T7769 T7770 arg1Of presence,of
R6119 T7769 T7772 arg1Of presence,in
R6120 T7769 T7776 arg1Of presence,","
R6121 T7769 T7778 arg1Of presence,similar
R6122 T7771 T7770 arg2Of Tax,of
R6123 T7775 T7772 arg2Of cells,in
R6124 T7775 T7773 arg1Of cells,HEK
R6125 T7775 T7774 arg1Of cells,293T
R6126 T7778 T7777 arg1Of similar,strikingly
R6127 T7778 T7779 arg1Of similar,to
R6128 T7781 T7779 arg2Of requirements,to
R6129 T7781 T7780 arg1Of requirements,the
R6130 T7781 T7782 arg1Of requirements,of
R6131 T7784 T7782 arg2Of inhibition,of
R6132 T7784 T7783 arg1Of inhibition,Foxp3
R6133 T7784 T7785 arg1Of inhibition,of
R6134 T7788 T7785 arg2Of activation,of
R6135 T7788 T7786 arg1Of activation,basal
R6136 T7788 T7787 arg1Of activation,NF-κB
R6137 T7788 T7789 arg2Of activation,shown
R6138 T7789 T7790 arg1Of shown,in
R6139 T7792 T7790 arg2Of 2B,in
R6140 T7792 T7791 arg1Of 2B,Figure
R6141 T7793 T7794 arg1Of Transactivation,of
R6142 T7793 T7798 arg1Of Transactivation,was
R6143 T7793 T7799 arg2Of Transactivation,stimulated
R6144 T7797 T7794 arg2Of LTR,of
R6145 T7797 T7795 arg1Of LTR,the
R6146 T7797 T7796 arg1Of LTR,HTLV-I
R6147 T7799 T7798 arg2Of stimulated,was
R6148 T7799 T7800 arg1Of stimulated,about
R6149 T7799 T7802 arg1Of stimulated,by
R6150 T7799 T7810 arg1Of stimulated,","
R6151 T7799 T7811 arg1Of stimulated,while
R6152 T7801 T7800 arg2Of 55-fold,about
R6153 T7803 T7802 arg2Of overexpression,by
R6154 T7803 T7804 arg1Of overexpression,of
R6155 T7805 T7804 arg2Of Tax,of
R6156 T7805 T7806 arg1Of Tax,(
R6157 T7808 T7806 arg2Of 4B,(
R6158 T7808 T7807 arg1Of 4B,Figure
R6159 T7809 T7806 arg3Of ),(
R6160 T7812 T7813 arg1Of transfection,of
R6161 T7812 T7815 arg1Of transfection,suppressed
R6162 T7814 T7813 arg2Of Foxp3,of
R6163 T7815 T7811 arg2Of suppressed,while
R6164 T7815 T7820 arg1Of suppressed,","
R6165 T7815 T7821 arg1Of suppressed,although
R6166 T7819 T7815 arg2Of activation,suppressed
R6167 T7819 T7816 arg1Of activation,Tax-dependent
R6168 T7819 T7817 arg1Of activation,HTLV-I
R6169 T7819 T7818 arg1Of activation,LTR
R6170 T7824 T7822 arg1Of activation,HTLV-I
R6171 T7824 T7823 arg1Of activation,LTR
R6172 T7824 T7825 arg1Of activation,in
R6173 T7824 T7832 arg1Of activation,is
R6174 T7824 T7833 arg1Of activation,independent
R6175 T7827 T7828 arg1Of presence,or
R6176 T7828 T7825 arg2Of or,in
R6177 T7828 T7826 arg1Of or,the
R6178 T7828 T7830 arg1Of or,of
R6179 T7829 T7828 arg2Of absence,or
R6180 T7831 T7830 arg2Of Tax,of
R6181 T7832 T7821 arg2Of is,although
R6182 T7833 T7832 arg2Of independent,is
R6183 T7833 T7834 arg1Of independent,of
R6184 T7835 T7836 arg1Of NF-κB,or
R6185 T7836 T7834 arg2Of or,of
R6186 T7837 T7836 arg2Of NF-AT,or
R6187 T7837 T7838 arg1Of NF-AT,(
R6188 T7841 T7838 arg2Of activator,(
R6189 T7841 T7839 arg1Of activator,another
R6190 T7841 T7840 arg1Of activator,transcriptional
R6191 T7841 T7842 arg2Of activator,known
R6192 T7841 T7844 arg1Of activator,interact
R6193 T7844 T7842 arg3Of interact,known
R6194 T7844 T7843 arg1Of interact,to
R6195 T7844 T7845 arg1Of interact,with
R6196 T7846 T7845 arg2Of Foxp3,with
R6197 T7847 T7838 arg3Of ),(
R6198 T7850 T7851 arg1Of overexpression,of
R6199 T7850 T7854 arg1Of overexpression,led
R6200 T7852 T7851 arg2Of ΔFKH,of
R6201 T7854 T7848 arg1Of led,Furthermore
R6202 T7854 T7849 arg1Of led,","
R6203 T7854 T7853 arg1Of led,also
R6204 T7854 T7855 arg1Of led,to
R6205 T7854 T7862 arg1Of led,to
R6206 T7854 T7866 arg1Of led,as
R6207 T7856 T7855 arg2Of suppression,to
R6208 T7856 T7857 arg1Of suppression,of
R6209 T7859 T7857 arg2Of transactivation,of
R6210 T7859 T7858 arg1Of transactivation,HTLV-I
R6211 T7859 T7860 arg1Of transactivation,by
R6212 T7861 T7860 arg2Of Tax,by
R6213 T7865 T7862 arg2Of extent,to
R6214 T7865 T7863 arg1Of extent,a
R6215 T7865 T7864 arg1Of extent,similar
R6216 T7868 T7866 arg2Of Foxp3,as
R6217 T7868 T7867 arg1Of Foxp3,full-length
R6218 T7868 T7869 arg1Of Foxp3,(
R6219 T7871 T7869 arg2Of 4B,(
R6220 T7871 T7870 arg1Of 4B,Figure
R6221 T7872 T7869 arg3Of ),(
R6222 T7875 T7873 arg1Of effects,The
R6223 T7875 T7874 arg1Of effects,suppressive
R6224 T7875 T7876 arg2Of effects,shown
R6225 T7875 T7882 arg1Of effects,were
R6226 T7876 T7877 arg1Of shown,in
R6227 T7879 T7878 arg1Of 4A,Figure
R6228 T7879 T7880 arg1Of 4A,and
R6229 T7880 T7877 arg2Of and,in
R6230 T7881 T7880 arg2Of 4B,and
R6231 T7882 T7883 arg1Of were,not
R6232 T7885 T7882 arg2Of result,were
R6233 T7885 T7884 arg1Of result,the
R6234 T7885 T7886 arg1Of result,of
R6235 T7887 T7886 arg2Of Foxp3,of
R6236 T7887 T7888 arg1Of Foxp3,down-regulating
R6237 T7888 T7896 arg1Of down-regulating,as
R6238 T7890 T7888 arg2Of expression,down-regulating
R6239 T7890 T7889 arg1Of expression,the
R6240 T7890 T7891 arg1Of expression,of
R6241 T7895 T7891 arg2Of plasmid,of
R6242 T7895 T7892 arg1Of plasmid,the
R6243 T7895 T7893 arg2Of plasmid,transfected
R6244 T7895 T7894 arg1Of plasmid,Tax
R6245 T7897 T7896 arg2Of determined,as
R6246 T7900 T7897 arg1Of RT-PCR,determined
R6247 T7900 T7898 arg2Of RT-PCR,by
R6248 T7900 T7899 arg1Of RT-PCR,real-time
R6249 T7900 T7901 arg1Of RT-PCR,(
R6250 T7903 T7901 arg2Of 4C,(
R6251 T7903 T7902 arg1Of 4C,Figure
R6252 T7904 T7901 arg3Of ),(
R6253 T7906 T7905 arg1Of results,These
R6254 T7906 T7908 arg1Of results,suggest
R6255 T7908 T7907 arg1Of suggest,strongly
R6256 T7910 T7911 arg1Of Foxp3,interacts
R6257 T7911 T7909 arg1Of interacts,that
R6258 T7911 T7912 arg1Of interacts,with
R6259 T7911 T7915 arg1Of interacts,in
R6260 T7911 T7922 arg1Of interacts,and
R6261 T7914 T7912 arg2Of regulators,with
R6262 T7914 T7913 arg1Of regulators,transcriptional
R6263 T7916 T7915 arg2Of addition,in
R6264 T7916 T7917 arg1Of addition,to
R6265 T7918 T7919 arg1Of NF-κB,and
R6266 T7919 T7917 arg2Of and,to
R6267 T7920 T7919 arg2Of NF-AT,and
R6268 T7922 T7908 arg2Of and,suggest
R6269 T7922 T7921 arg1Of and,","
R6270 T7923 T7922 arg2Of that,and
R6271 T7927 T7924 arg1Of domain,the
R6272 T7927 T7925 arg1Of domain,carboxyl-terminal
R6273 T7927 T7926 arg1Of domain,FKH
R6274 T7927 T7929 arg1Of domain,and
R6275 T7929 T7928 arg1Of and,","
R6276 T7929 T7936 arg1Of and,are
R6277 T7929 T7938 arg2Of and,required
R6278 T7931 T7929 arg2Of localization,and
R6279 T7931 T7930 arg1Of localization,therefore
R6280 T7931 T7932 arg1Of localization,to
R6281 T7934 T7932 arg2Of nucleus,to
R6282 T7934 T7933 arg1Of nucleus,the
R6283 T7938 T7923 arg2Of required,that
R6284 T7938 T7935 arg1Of required,","
R6285 T7938 T7936 arg2Of required,are
R6286 T7938 T7937 arg1Of required,not
R6287 T7938 T7939 arg1Of required,for
R6288 T7940 T7939 arg2Of inhibition,for
R6289 T7940 T7941 arg1Of inhibition,of
R6290 T7945 T7941 arg2Of activation,of
R6291 T7945 T7942 arg1Of activation,Tax-mediated
R6292 T7945 T7943 arg1Of activation,HTLV-I
R6293 T7945 T7944 arg1Of activation,LTR
R6294 T7945 T7946 arg1Of activation,(
R6295 T7948 T7946 arg2Of in,(
R6296 T7948 T7947 arg1Of in,even
R6297 T7951 T7948 arg2Of cells,in
R6298 T7951 T7949 arg1Of cells,HEK
R6299 T7951 T7950 arg1Of cells,293T
R6300 T7952 T7946 arg3Of ),(
R6301 T7954 T7953 arg1Of determine,To
R6302 T7956 T7957 arg1Of Foxp3,inhibited
R6303 T7957 T7954 arg2Of inhibited,determine
R6304 T7957 T7955 arg1Of inhibited,whether
R6305 T7957 T7963 arg1Of inhibited,by
R6306 T7960 T7957 arg2Of functions,inhibited
R6307 T7960 T7958 arg1Of functions,the
R6308 T7960 T7959 arg1Of functions,transactivation
R6309 T7960 T7961 arg1Of functions,of
R6310 T7962 T7961 arg2Of Tax,of
R6311 T7965 T7963 arg2Of associating,by
R6312 T7965 T7964 arg1Of associating,directly
R6313 T7965 T7966 arg1Of associating,with
R6314 T7969 T7966 arg2Of protein,with
R6315 T7969 T7967 arg1Of protein,this
R6316 T7969 T7968 arg1Of protein,viral
R6317 T7971 T7954 arg1Of we,determine
R6318 T7971 T7972 arg1Of we,generated
R6319 T7972 T7953 modOf generated,To
R6320 T7972 T7970 arg1Of generated,","
R6321 T7975 T7972 arg2Of vector,generated
R6322 T7975 T7973 arg1Of vector,an
R6323 T7975 T7974 arg1Of vector,expression
R6324 T7975 T7976 arg2Of vector,in
R6325 T7975 T7977 arg1Of vector,which
R6326 T7979 T7978 arg1Of Tax,HTLV-I
R6327 T7979 T7980 arg1Of Tax,was
R6328 T7979 T7981 arg2Of Tax,fused
R6329 T7981 T7976 arg1Of fused,in
R6330 T7981 T7980 arg2Of fused,was
R6331 T7981 T7983 arg1Of fused,to
R6332 T7983 T7982 arg1Of to,in-frame
R6333 T7986 T7983 arg2Of terminus,to
R6334 T7986 T7984 arg1Of terminus,the
R6335 T7986 T7985 arg1Of terminus,carboxyl
R6336 T7986 T7987 arg1Of terminus,of
R6337 T7991 T7987 arg2Of domain,of
R6338 T7991 T7988 arg1Of domain,the
R6339 T7991 T7989 arg1Of domain,Gal4
R6340 T7991 T7990 arg1Of domain,DNA-binding
R6341 T7991 T7992 arg1Of domain,(
R6342 T7993 T7992 arg2Of Gal4-BD,(
R6343 T7994 T7992 arg3Of ),(
R6344 T7998 T7995 arg1Of protein,This
R6345 T7998 T7996 arg1Of protein,Gal4-BD-Tax
R6346 T7998 T7997 arg1Of protein,fusion
R6347 T7998 T7999 arg1Of protein,activated
R6348 T7999 T8010 arg1Of activated,","
R6349 T7999 T8011 arg1Of activated,while
R6350 T8000 T7999 arg2Of transcription,activated
R6351 T8000 T8001 arg1Of transcription,of
R6352 T8004 T8001 arg2Of promoter,of
R6353 T8004 T8002 arg1Of promoter,a
R6354 T8004 T8003 arg1Of promoter,synthetic
R6355 T8004 T8005 arg1Of promoter,containing
R6356 T8009 T8005 arg2Of sites,containing
R6357 T8009 T8006 arg1Of sites,five
R6358 T8009 T8007 arg1Of sites,Gal4
R6359 T8009 T8008 arg1Of sites,binding
R6360 T8012 T8013 arg1Of Gal4-BD,was
R6361 T8012 T8014 arg1Of Gal4-BD,insufficient
R6362 T8012 T8016 arg1Of Gal4-BD,stimulate
R6363 T8013 T8011 arg2Of was,while
R6364 T8014 T8013 arg2Of insufficient,was
R6365 T8016 T8014 arg2Of stimulate,insufficient
R6366 T8016 T8015 arg1Of stimulate,to
R6367 T8016 T8018 arg1Of stimulate,by
R6368 T8017 T8016 arg2Of transcription,stimulate
R6369 T8019 T8018 arg2Of itself,by
R6370 T8019 T8020 arg1Of itself,(
R6371 T8022 T8020 arg2Of 4D,(
R6372 T8022 T8021 arg1Of 4D,Figure
R6373 T8023 T8020 arg3Of ),(
R6374 T8024 T8025 arg1Of Transactivation,of
R6375 T8024 T8029 arg1Of Transactivation,by
R6376 T8024 T8031 arg1Of Transactivation,remained
R6377 T8024 T8033 arg1Of Transactivation,unaffected
R6378 T8028 T8025 arg2Of promoter,of
R6379 T8028 T8026 arg1Of promoter,the
R6380 T8028 T8027 arg1Of promoter,Gal4-resposive
R6381 T8030 T8029 arg2Of Gal4-BD-Tax,by
R6382 T8031 T8047 arg1Of remained,","
R6383 T8031 T8048 modOf remained,suggesting
R6384 T8033 T8031 arg2Of unaffected,remained
R6385 T8033 T8032 arg1Of unaffected,relatively
R6386 T8033 T8034 arg1Of unaffected,by
R6387 T8035 T8034 arg2Of overexpression,by
R6388 T8035 T8036 arg1Of overexpression,of
R6389 T8038 T8039 arg1Of EGFP,(
R6390 T8038 T8042 arg1Of EGFP,","
R6391 T8040 T8039 arg2Of control,(
R6392 T8041 T8039 arg3Of ),(
R6393 T8042 T8037 arg1Of ",",either
R6394 T8113 T8111 arg3Of direct,shown
R6395 T8113 T8112 arg1Of direct,to
R6396 T8042 T8045 arg1Of ",",or
R6397 T8115 T8113 arg2Of expression,direct
R6398 T8115 T8114 arg1Of expression,the
R6399 T8115 T8116 arg1Of expression,of
R6400 T8043 T8042 arg2Of Foxp3,","
R6401 T8118 T8116 arg2Of antigens,of
R6402 T8118 T8117 arg1Of antigens,viral
R6403 T8119 T8124 arg1Of ",",and
R6404 T8120 T8119 arg2Of produce,","
R6405 T8045 T8036 arg2Of or,of
R6406 T8122 T8120 arg2Of virus,produce
R6407 T8122 T8121 arg1Of virus,infectious
R6408 T8124 T8123 arg1Of and,","
R6409 T8124 T8135 arg1Of and,[
R6410 T8045 T8044 arg1Of or,","
R6411 T8125 T8124 arg2Of transform,and
R6412 T8046 T8045 arg2Of ΔFKH,or
R6413 T8128 T8125 arg2Of cells,transform
R6414 T8128 T8126 arg1Of cells,CD4+
R6415 T8128 T8127 arg1Of cells,T
R6416 T8128 T8131 arg1Of cells,vitro
R6417 T8128 T8134 arg1Of cells,vivo
R6418 T8050 T8051 arg1Of Foxp3,does
R6419 T8131 T8130 arg1Of vitro,in
R6420 T8131 T8132 arg1Of vitro,and
R6421 T8132 T8129 arg1Of and,both
R6422 T8134 T8132 arg2Of vivo,and
R6423 T8134 T8133 arg1Of vivo,in
R6424 T8136 T8135 arg2Of "31,32",[
R6425 T8050 T8053 arg1Of Foxp3,repress
R6426 T8137 T8135 arg3Of ],[
R6427 T8053 T8048 arg2Of repress,suggesting
R6428 T8140 T8138 arg2Of h,After
R6429 T8140 T8139 arg1Of h,24
R6430 T8053 T8049 arg1Of repress,that
R6431 T8053 T8051 arg2Of repress,does
R6432 T8143 T8142 arg1Of amount,the
R6433 T8143 T8144 arg1Of amount,of
R6434 T8143 T8155 arg1Of amount,was
R6435 T8143 T8156 arg2Of amount,detected
R6436 T8053 T8052 arg1Of repress,not
R6437 T8053 T8056 arg1Of repress,by
R6438 T8055 T8053 arg2Of transactivation,repress
R6439 T8147 T8144 arg2Of expression,of
R6440 T8147 T8145 arg1Of expression,viral
R6441 T8147 T8146 arg1Of expression,antigen
R6442 T8055 T8054 arg1Of transactivation,Tax
R6443 T8058 T8056 arg2Of interfacing,by
R6444 T8153 T8149 arg2Of mRNA,in
R6445 T8153 T8150 arg1Of mRNA,this
R6446 T8153 T8151 arg1Of mRNA,case
R6447 T8153 T8152 arg1Of mRNA,Tax
R6448 T8156 T8138 arg1Of detected,After
R6449 T8156 T8141 arg1Of detected,","
R6450 T8156 T8148 arg1Of detected,","
R6451 T8156 T8149 arg1Of detected,in
R6452 T8156 T8154 arg1Of detected,","
R6453 T8156 T8155 arg2Of detected,was
R6454 T8058 T8057 arg1Of interfacing,directly
R6455 T8162 T8156 arg1Of assay,detected
R6456 T8162 T8157 arg2Of assay,by
R6457 T8162 T8158 arg1Of assay,a
R6458 T8162 T8159 arg1Of assay,sensitive
R6459 T8162 T8160 arg1Of assay,real-time
R6460 T8162 T8161 arg1Of assay,RT-PCR
R6461 T8058 T8059 arg1Of interfacing,with
R6462 T8063 T8059 arg2Of protein,with
R6463 T8164 T8163 arg2Of illustrated,As
R6464 T8164 T8165 arg1Of illustrated,in
R6465 T8166 T8165 arg2Of Figure,in
R6466 T8166 T8167 arg1Of Figure,5
R6467 T8170 T8169 arg1Of level,the
R6468 T8170 T8171 arg1Of level,of
R6469 T8170 T8177 arg1Of level,was
R6470 T8170 T8178 arg2Of level,down-regulated
R6471 T8063 T8060 arg1Of protein,the
R6472 T8173 T8171 arg2Of mRNA,of
R6473 T8173 T8172 arg1Of mRNA,Tax
R6474 T8173 T8174 arg2Of mRNA,synthesized
R6475 T8174 T8175 arg1Of synthesized,from
R6476 T8063 T8061 arg1Of protein,HTLV-I
R6477 T8063 T8062 arg1Of protein,Tax
R6478 T8176 T8175 arg2Of ACH,from
R6479 T8065 T8064 arg1Of confirm,To
R6480 T8178 T8163 arg1Of down-regulated,As
R6481 T8178 T8168 arg1Of down-regulated,","
R6482 T8178 T8177 arg2Of down-regulated,was
R6483 T8178 T8179 arg1Of down-regulated,in
R6484 T8178 T8184 arg1Of down-regulated,compared
R6485 T8181 T8179 arg2Of presence,in
R6486 T8181 T8180 arg1Of presence,the
R6487 T8181 T8182 arg1Of presence,of
R6488 T8067 T8068 arg1Of Foxp3,had
R6489 T8183 T8182 arg2Of Foxp3,of
R6490 T8185 T8184 arg2Of to,compared
R6491 T8185 T8192 arg1Of to,of
R6492 T8187 T8185 arg2Of level,to
R6493 T8187 T8186 arg1Of level,the
R6494 T8187 T8188 arg2Of level,produced
R6495 T8188 T8189 arg1Of produced,in
R6496 T8068 T8065 arg2Of had,confirm
R6497 T8189 T8190 arg1Of in,the
R6498 T8191 T8189 arg2Of presence,in
R6499 T8068 T8066 arg1Of had,that
R6500 T8068 T8072 arg1Of had,on
R6501 T8196 T8193 arg1Of ΔFKH,the
R6502 T8196 T8194 arg1Of ΔFKH,control
R6503 T8196 T8195 arg1Of ΔFKH,vector.
R6504 T8196 T8197 arg1Of ΔFKH,did
R6505 T8196 T8199 arg1Of ΔFKH,have
R6506 T8071 T8068 arg2Of effect,had
R6507 T8199 T8177 modOf have,was
R6508 T8199 T8197 arg2Of have,did
R6509 T8199 T8198 arg1Of have,not
R6510 T8202 T8199 arg2Of affect,have
R6511 T8202 T8200 arg1Of affect,a
R6512 T8202 T8201 arg1Of affect,discernable
R6513 T8202 T8203 arg1Of affect,on
R6514 T8071 T8069 arg1Of effect,a
R6515 T8205 T8203 arg2Of expression,on
R6516 T8205 T8204 arg1Of expression,Tax
R6517 T8071 T8070 arg1Of effect,direct
R6518 T8207 T8206 arg1Of data,These
R6519 T8207 T8208 arg1Of data,indicate
R6520 T8074 T8072 arg2Of replication,on
R6521 T8074 T8073 arg1Of replication,HTLV-I
R6522 T8210 T8211 arg1Of Foxp3,is
R6523 T8210 T8212 arg1Of Foxp3,capable
R6524 T8210 T8214 arg1Of Foxp3,repressing
R6525 T8076 T8065 arg1Of we,confirm
R6526 T8211 T8208 arg2Of is,indicate
R6527 T8211 T8209 arg1Of is,that
R6528 T8212 T8211 arg2Of capable,is
R6529 T8212 T8213 arg1Of capable,of
R6530 T8214 T8213 arg2Of repressing,of
R6531 T8076 T8077 arg1Of we,transfected
R6532 T8216 T8214 arg2Of expression,repressing
R6533 T8216 T8215 arg1Of expression,the
R6534 T8216 T8217 arg1Of expression,of
R6535 T8077 T8064 modOf transfected,To
R6536 T8218 T8217 arg2Of Tax,of
R6537 T8218 T8219 arg1Of Tax,from
R6538 T8077 T8075 arg1Of transfected,","
R6539 T8077 T8081 arg1Of transfected,with
R6540 T8077 T8092 arg1Of transfected,[
R6541 T8077 T8095 arg1Of transfected,in
R6542 T8224 T8219 arg2Of clone,from
R6543 T8224 T8220 arg1Of clone,an
R6544 T8224 T8221 arg1Of clone,infectious
R6545 T8224 T8222 arg1Of clone,HTLV-I
R6546 T8224 T8223 arg1Of clone,molecular
R6547 T8080 T8077 arg2Of cells,transfected
R6548 T8080 T8078 arg1Of cells,HEK
R6549 T8080 T8079 arg1Of cells,293T
R6550 T8087 T8081 arg2Of clone,with
R6552 T8087 T8082 arg1Of clone,a
R6554 T8087 T8083 arg1Of clone,well-characterized
R6555 T8087 T8084 arg1Of clone,HTLV-I
R6556 T8087 T8085 arg1Of clone,infectious
R6557 T8087 T8086 arg1Of clone,molecular
R6558 T8087 T8088 arg1Of clone,(
R6559 T8089 T8088 arg2Of termed,(
R6560 T8090 T8089 arg3Of ACH,termed
R6561 T8091 T8088 arg3Of ),(
R6562 T8093 T8092 arg2Of 30,[
R6563 T8094 T8092 arg3Of ],[
R6564 T8097 T8095 arg2Of presence,in
R6565 T8097 T8096 arg1Of presence,the
R6566 T8097 T8098 arg1Of presence,of
R6567 T8100 T8099 arg1Of Foxp3,full-length
R6568 T8100 T8101 arg1Of Foxp3,","
R6569 T8101 T8104 arg1Of ",",or
R6570 T8102 T8101 arg2Of ΔFKH,","
R6571 T8104 T8098 arg2Of or,of
R6572 T8104 T8103 arg1Of or,","
R6573 T8106 T8104 arg2Of vector,or
R6574 T8106 T8105 arg1Of vector,control
R6575 T8107 T8108 arg1Of ACH,has
R6576 T8107 T8109 arg1Of ACH,been
R6577 T8107 T8111 arg2Of ACH,shown
R6578 T8107 T8113 arg1Of ACH,direct
R6579 T8107 T8120 arg1Of ACH,produce
R6580 T8107 T8125 arg1Of ACH,transform
R6581 T8111 T8108 arg2Of shown,has
R6582 T8111 T8109 arg2Of shown,been
R6583 T8111 T8110 arg1Of shown,previously
R6584 T8111 T8119 arg1Of shown,","
R687 T604 T603 arg2Of Foxp3,for
R7114 T9288 T9285 arg2Of Expression,Increased
R7115 T9288 T9286 arg1Of Expression,Foxp3
R7116 T9288 T9287 arg1Of Expression,Protein
R7117 T9288 T9289 arg1Of Expression,Is
R7118 T9288 T9290 arg2Of Expression,Associated
R7119 T9290 T9289 arg2Of Associated,Is
R7120 T9290 T9291 arg1Of Associated,with
R7121 T9295 T9291 arg2Of Load,with
R7122 T9295 T9292 arg1Of Load,Low
R7123 T9295 T9293 arg1Of Load,HTLV-I
R7124 T9295 T9294 arg1Of Load,Proviral
R7125 T9297 T9298 arg1Of Foxp3,is
R7126 T9297 T9299 arg2Of Foxp3,expressed
R7127 T9299 T9296 arg2Of expressed,Since
R7128 T9299 T9298 arg2Of expressed,is
R7129 T9299 T9301 arg1Of expressed,exclusively
R7130 T9299 T9302 arg1Of expressed,within
R7131 T9299 T9313 arg1Of expressed,[
R7132 T9301 T9300 arg1Of exclusively,almost
R7133 T9305 T9302 arg2Of cells,within
R7134 T9305 T9303 arg1Of cells,CD4+CD25+
R7135 T9305 T9304 arg1Of cells,T
R7136 T9305 T9306 arg1Of cells,","
R7137 T9310 T9306 arg2Of reservoir,","
R7138 T9310 T9307 arg1Of reservoir,a
R7139 T9310 T9308 arg1Of reservoir,major
R7140 T9310 T9309 arg1Of reservoir,viral
R7141 T9310 T9311 arg1Of reservoir,for
R7142 T9312 T9311 arg2Of HTLV-I,for
R7143 T9314 T9313 arg2Of 33,[
R7144 T9315 T9313 arg3Of ],[
R7145 T9318 T9296 arg1Of was,Since
R7146 T9318 T9316 arg1Of was,","
R7147 T9319 T9318 arg2Of important,was
R7148 T9321 T9317 arg1Of determine,it
R7149 T9321 T9318 arg1Of determine,was
R7150 T9321 T9319 arg1Of determine,important
R7151 T9321 T9320 arg1Of determine,to
R7152 T9323 T9324 arg1Of there,was
R7153 T9324 T9321 arg2Of was,determine
R7154 T9324 T9322 arg1Of was,whether
R7155 T9326 T9324 arg2Of association,was
R7156 T9326 T9325 arg1Of association,an
R7157 T9326 T9327 arg1Of association,between
R7158 T9328 T9329 arg1Of Foxp3,and
R7159 T9330 T9329 arg2Of HTLV-I,and
R7160 T9331 T9327 arg2Of replication,between
R7161 T9331 T9328 arg1Of replication,Foxp3
R7162 T9331 T9330 arg1Of replication,HTLV-I
R7163 T9331 T9332 arg1Of replication,in
R7164 T9334 T9332 arg2Of patients,in
R7165 T9334 T9333 arg1Of patients,infected
R7166 T9335 T9337 arg1Of We,quantitated
R7167 T9337 T9336 arg1Of quantitated,therefore
R7168 T9337 T9362 arg1Of quantitated,by
R7169 T9341 T9338 arg1Of expression,the
R7170 T9341 T9339 arg1Of expression,Foxp3
R7171 T9341 T9340 arg1Of expression,protein
R7172 T9341 T9342 arg1Of expression,in
R7173 T9341 T9346 arg1Of expression,by
R7174 T9341 T9349 arg1Of expression,and
R7175 T9345 T9342 arg2Of cells,in
R7176 T9345 T9343 arg1Of cells,CD4+CD25+
R7177 T9345 T9344 arg1Of cells,T
R7178 T9348 T9346 arg2Of cytometry,by
R7179 T9348 T9347 arg1Of cytometry,flow
R7180 T9349 T9337 arg2Of and,quantitated
R7181 T9353 T9349 arg2Of load,and
R7182 T9353 T9350 arg1Of load,the
R7183 T9353 T9351 arg1Of load,HTLV-I
R7184 T9353 T9352 arg1Of load,proviral
R7185 T9353 T9354 arg1Of load,(
R7186 T9357 T9354 arg2Of marker,(
R7187 T9357 T9355 arg1Of marker,a
R7188 T9357 T9356 arg1Of marker,surrogate
R7189 T9357 T9358 arg1Of marker,of
R7190 T9360 T9358 arg2Of replication,of
R7191 T9360 T9359 arg1Of replication,viral
R7192 T9361 T9354 arg3Of ),(
R7193 T9364 T9362 arg2Of PCR,by
R7194 T9364 T9363 arg1Of PCR,real-time
R7195 T9364 T9365 arg1Of PCR,from
R7196 T9367 T9366 arg1Of patients,eight
R7197 T9367 T9368 arg1Of patients,with
R7198 T9367 T9370 arg1Of patients,and
R7199 T9369 T9368 arg2Of HAM/TSP,with
R7200 T9370 T9365 arg2Of and,from
R7201 T9373 T9370 arg2Of carriers,and
R7202 T9373 T9371 arg1Of carriers,eight
R7203 T9373 T9372 arg1Of carriers,asymptomatic
R7204 T9373 T9374 arg1Of carriers,(
R7205 T9375 T9374 arg2Of ACs,(
R7206 T9376 T9374 arg3Of ),(
R7207 T9378 T9377 arg1Of data,The
R7208 T9378 T9379 arg1Of data,from
R7209 T9378 T9382 arg1Of data,is
R7210 T9378 T9383 arg2Of data,summarized
R7211 T9381 T9379 arg2Of analysis,from
R7212 T9381 T9380 arg1Of analysis,this
R7213 T9383 T9382 arg2Of summarized,is
R7214 T9383 T9384 arg1Of summarized,in
R7215 T9386 T9384 arg2Of 1,in
R7216 T9386 T9385 arg1Of 1,Table
R7217 T9388 T9387 arg2Of expected,As
R7218 T9390 T9391 arg1Of patients,with
R7219 T9390 T9393 arg1Of patients,exhibited
R7220 T9392 T9391 arg2Of HAM/TSP,with
R7221 T9393 T9387 arg1Of exhibited,As
R7222 T9393 T9389 arg1Of exhibited,","
R7223 T9393 T9412 arg1Of exhibited,compared
R7224 T9395 T9394 arg1Of higher,significantly
R7225 T9397 T9393 arg2Of loads,exhibited
R7226 T9397 T9395 arg1Of loads,higher
R7227 T9397 T9396 arg1Of loads,proviral
R7228 T9397 T9398 arg1Of loads,(
R7229 T9397 T9407 arg1Of loads,(
R7230 T9399 T9398 arg2Of indicated,(
R7231 T9399 T9400 arg1Of indicated,as
R7232 T9405 T9400 arg2Of cells,as
R7233 T9405 T9401 arg1Of cells,HTLV-I
R7234 T9405 T9402 arg1Of cells,proviral
R7235 T9405 T9403 arg1Of cells,DNA
R7236 T9405 T9404 arg1Of cells,copies/100
R7237 T9406 T9398 arg3Of ),(
R7238 T9408 T9409 arg1Of 34.68,±
R7239 T9409 T9407 arg2Of ±,(
R7240 T9410 T9409 arg2Of 23.19,±
R7241 T9411 T9407 arg3Of ),(
R7242 T9413 T9412 arg2Of to,compared
R7243 T9414 T9413 arg2Of ACs,to
R7244 T9414 T9415 arg1Of ACs,(
R7245 T9414 T9420 arg1Of ACs,(
R7246 T9416 T9417 arg1Of 4.75,±
R7247 T9417 T9415 arg2Of ±,(
R7248 T9418 T9417 arg2Of 5.47,±
R7249 T9419 T9415 arg3Of ),(
R7250 T9421 T9420 arg2Of p,(
R7251 T9421 T9422 arg1Of p,=
R7252 T9421 T9423 arg1Of p,0.0008
R7253 T9424 T9420 arg3Of ),(
R7254 T9426 T9425 arg1Of percentage,The
R7255 T9426 T9427 arg1Of percentage,of
R7256 T9426 T9430 arg1Of percentage,within
R7257 T9426 T9436 arg1Of percentage,was
R7258 T9426 T9438 arg1Of percentage,greater
R7259 T9429 T9427 arg2Of cells,of
R7260 T9429 T9428 arg1Of cells,Foxp3+
R7261 T9435 T9430 arg2Of population,within
R7262 T9435 T9431 arg1Of population,the
R7263 T9435 T9432 arg1Of population,CD4+CD25+
R7264 T9435 T9433 arg1Of population,T
R7265 T9435 T9434 arg1Of population,cell
R7266 T9436 T9439 arg1Of was,in
R7267 T9436 T9446 arg1Of was,than
R7268 T9438 T9436 arg2Of greater,was
R7269 T9438 T9437 arg1Of greater,significantly
R7270 T9440 T9439 arg2Of ACs,in
R7271 T9440 T9441 arg1Of ACs,(
R7272 T9442 T9443 arg1Of 43.23,±
R7273 T9443 T9441 arg2Of ±,(
R7274 T9444 T9443 arg2Of 12.95,±
R7275 T9445 T9441 arg3Of ),(
R7276 T9447 T9446 arg2Of in,than
R7277 T9449 T9447 arg2Of patients,in
R7278 T9449 T9448 arg1Of patients,HAM/TSP
R7279 T9449 T9450 arg1Of patients,(
R7280 T9449 T9455 arg1Of patients,(
R7281 T9451 T9452 arg1Of 18.59,±
R7282 T9452 T9450 arg2Of ±,(
R7283 T9453 T9452 arg2Of 5.77,±
R7284 T9454 T9450 arg3Of ),(
R7285 T9456 T9455 arg2Of p,(
R7286 T9456 T9457 arg1Of p,=
R7287 T9456 T9458 arg1Of p,0.0033
R7288 T9459 T9455 arg3Of ),(
R7289 T9461 T9460 arg1Of data,These
R7290 T9461 T9462 arg1Of data,suggest
R7291 T9465 T9464 arg1Of levels,high
R7292 T9465 T9466 arg1Of levels,of
R7293 T9465 T9470 arg1Of levels,are
R7294 T9465 T9471 arg2Of levels,associated
R7295 T9469 T9466 arg2Of expression,of
R7296 T9469 T9467 arg1Of expression,Foxp3
R7297 T9469 T9468 arg1Of expression,protein
R7298 T9471 T9462 arg2Of associated,suggest
R7299 T9471 T9463 arg1Of associated,that
R7300 T9471 T9470 arg2Of associated,are
R7301 T9471 T9472 arg1Of associated,with
R7302 T9471 T9477 arg1Of associated,vivo
R7303 T9475 T9472 arg2Of replication,with
R7304 T9475 T9473 arg2Of replication,reduced
R7305 T9475 T9474 arg1Of replication,HTLV-I
R7306 T9477 T9476 arg1Of vivo,in
R7307 T9478 T9480 arg1Of They,support
R7308 T9480 T9479 arg1Of support,also
R7309 T9483 T9480 arg2Of reports,support
R7310 T9483 T9481 arg1Of reports,our
R7311 T9483 T9482 arg1Of reports,recent
R7312 T9487 T9485 arg1Of loads,high
R7313 T9487 T9486 arg1Of loads,proviral
R7314 T9487 T9488 arg1Of loads,","
R7315 T9487 T9489 arg1Of loads,which
R7316 T9487 T9490 arg1Of loads,have
R7317 T9487 T9491 arg1Of loads,been
R7318 T9487 T9492 arg2Of loads,shown
R7319 T9487 T9494 arg1Of loads,correlate
R7320 T9487 T9503 arg1Of loads,are
R7321 T9487 T9504 arg2Of loads,associated
R7322 T9492 T9490 arg2Of shown,have
R7323 T9492 T9491 arg2Of shown,been
R7324 T9494 T9492 arg3Of correlate,shown
R7325 T9494 T9493 arg1Of correlate,to
R7326 T9494 T9495 arg1Of correlate,with
R7327 T9494 T9499 arg1Of correlate,in
R7328 T9498 T9495 arg2Of mRNA,with
R7329 T9498 T9496 arg1Of mRNA,high
R7330 T9498 T9497 arg1Of mRNA,Tax
R7331 T9501 T9499 arg2Of patients,in
R7332 T9501 T9500 arg1Of patients,HTLV-I-infected
R7333 T9504 T9483 arg2Of associated,reports
R7334 T9504 T9484 arg1Of associated,that
R7335 T9504 T9502 arg1Of associated,","
R7336 T9504 T9503 arg2Of associated,are
R7337 T9504 T9505 arg1Of associated,with
R7338 T9504 T9509 arg1Of associated,[
R7339 T9508 T9505 arg2Of expression,with
R7340 T9508 T9506 arg2Of expression,reduced
R7341 T9508 T9507 arg1Of expression,Foxp3
R7342 T9510 T9509 arg2Of "8,34",[
R7343 T9511 T9509 arg3Of ],[
R8177 T10638 T10639 arg1Of CREB,Is
R8178 T10641 T10639 arg2Of Target,Is
R8179 T10641 T10640 arg1Of Target,a
R8180 T10641 T10642 arg1Of Target,for
R8181 T10644 T10642 arg2Of Repression,for
R8182 T10644 T10643 arg1Of Repression,Transcriptional
R8183 T10644 T10645 arg1Of Repression,by
R8184 T10646 T10645 arg2Of Foxp3,by
R8185 T10648 T10649 arg1Of Foxp3,could
R8186 T10648 T10650 arg1Of Foxp3,down-regulate
R8187 T10648 T10662 arg1Of Foxp3,inhibit
R8188 T10650 T10649 arg2Of down-regulate,could
R8189 T10650 T10661 arg1Of down-regulate,and
R8190 T10652 T10650 arg2Of transactivation,down-regulate
R8191 T10652 T10651 arg1Of transactivation,Tax-dependent
R8192 T10652 T10653 arg1Of transactivation,of
R8193 T10656 T10653 arg2Of LTR,of
R8194 T10656 T10654 arg1Of LTR,the
R8195 T10656 T10655 arg1Of LTR,HTLV-I
R8196 T10656 T10657 arg1Of LTR,(
R8197 T10659 T10657 arg2Of 4B,(
R8198 T10659 T10658 arg1Of 4B,Figure
R8199 T10660 T10657 arg3Of ),(
R8200 T10661 T10647 arg2Of and,Although
R8201 T10662 T10661 arg2Of inhibit,and
R8202 T10664 T10662 arg2Of expression,inhibit
R8203 T10664 T10663 arg1Of expression,Tax
R8204 T10664 T10665 arg1Of expression,from
R8205 T10669 T10665 arg2Of clone,from
R8206 T10669 T10666 arg1Of clone,an
R8207 T10669 T10667 arg1Of clone,infectious
R8208 T10669 T10668 arg1Of clone,molecular
R8209 T10669 T10670 arg1Of clone,(
R8210 T10671 T10670 arg2Of Figure,(
R8211 T10671 T10672 arg1Of Figure,5
R8212 T10673 T10670 arg3Of ),(
R8213 T10675 T10676 arg1Of Foxp3,failed
R8214 T10675 T10678 arg1Of Foxp3,modulate
R8215 T10676 T10647 arg1Of failed,Although
R8216 T10676 T10674 arg1Of failed,","
R8217 T10678 T10676 arg2Of modulate,failed
R8218 T10678 T10677 arg1Of modulate,to
R8219 T10678 T10681 arg1Of modulate,in
R8220 T10680 T10678 arg2Of function,modulate
R8221 T10680 T10679 arg1Of function,Tax
R8222 T10681 T10682 arg1Of in,the
R8223 T10681 T10684 arg1Of in,of
R8224 T10683 T10681 arg2Of absence,in
R8225 T10687 T10681 arg3Of promoter,in
R8226 T10687 T10685 arg1Of promoter,the
R8227 T10687 T10686 arg1Of promoter,viral
R8228 T10687 T10688 arg1Of promoter,(
R8229 T10690 T10688 arg2Of 4D,(
R8230 T10690 T10689 arg1Of 4D,Figure
R8231 T10691 T10688 arg3Of ),(
R8232 T10693 T10692 arg1Of results,These
R8233 T10693 T10694 arg1Of results,led
R8234 T10695 T10694 arg2Of us,led
R8235 T10695 T10697 arg1Of us,hypothesize
R8236 T10697 T10694 arg3Of hypothesize,led
R8237 T10697 T10696 arg1Of hypothesize,to
R8238 T10699 T10700 arg1Of Foxp3,acts
R8239 T10699 T10706 arg1Of Foxp3,interacting
R8240 T10700 T10697 arg2Of acts,hypothesize
R8241 T10700 T10698 arg1Of acts,that
R8242 T10700 T10701 arg1Of acts,on
R8243 T10700 T10705 arg1Of acts,by
R8244 T10704 T10701 arg2Of expression,on
R8245 T10704 T10702 arg1Of expression,HTLV-I
R8246 T10704 T10703 arg1Of expression,gene
R8247 T10706 T10705 arg2Of interacting,by
R8248 T10706 T10707 arg1Of interacting,with
R8249 T10708 T10707 arg2Of proteins,with
R8250 T10708 T10709 arg1Of proteins,important
R8251 T10709 T10710 arg1Of important,for
R8252 T10711 T10710 arg2Of driving,for
R8253 T10711 T10716 arg1Of driving,vivo
R8254 T10714 T10711 arg2Of activity,driving
R8255 T10714 T10712 arg1Of activity,HTLV-I
R8256 T10714 T10713 arg1Of activity,LTR
R8257 T10716 T10715 arg1Of vivo,in
R8258 T10718 T10717 arg1Of studies,Previous
R8259 T10718 T10719 arg1Of studies,have
R8260 T10718 T10720 arg1Of studies,demonstrated
R8261 T10720 T10719 arg2Of demonstrated,have
R8262 T10724 T10722 arg1Of elements,the
R8263 T10724 T10723 arg1Of elements,Tax-responsive
R8264 T10724 T10725 arg1Of elements,within
R8265 T10724 T10729 arg1Of elements,play
R8266 T10728 T10725 arg2Of LTR,within
R8267 T10728 T10726 arg1Of LTR,the
R8268 T10728 T10727 arg1Of LTR,HTLV-I
R8269 T10729 T10720 arg2Of play,demonstrated
R8270 T10729 T10721 arg1Of play,that
R8271 T10729 T10733 arg1Of play,in
R8272 T10732 T10729 arg2Of role,play
R8273 T10732 T10730 arg1Of role,a
R8274 T10732 T10731 arg1Of role,crucial
R8275 T10734 T10733 arg2Of driving,in
R8276 T10734 T10741 arg1Of driving,[
R8277 T10736 T10734 arg2Of transactivation,driving
R8278 T10736 T10735 arg1Of transactivation,Tax-mediated
R8279 T10736 T10737 arg1Of transactivation,of
R8280 T10740 T10737 arg2Of LTR,of
R8281 T10740 T10738 arg1Of LTR,the
R8282 T10740 T10739 arg1Of LTR,HTLV-I
R8283 T10742 T10741 arg2Of 18,[
R8284 T10743 T10741 arg3Of ],[
R8285 T10746 T10744 arg1Of elements,The
R8286 T10746 T10745 arg1Of elements,Tax-responsive
R8287 T10746 T10747 arg1Of elements,have
R8288 T10746 T10748 arg1Of elements,been
R8289 T10746 T10749 arg2Of elements,shown
R8290 T10746 T10751 arg1Of elements,resemble
R8291 T10746 T10756 arg1Of elements,bind
R8292 T10746 T10765 arg1Of elements,facilitate
R8293 T10749 T10747 arg2Of shown,have
R8294 T10749 T10748 arg2Of shown,been
R8295 T10749 T10755 arg1Of shown,","
R8296 T10751 T10749 arg3Of resemble,shown
R8297 T10751 T10750 arg1Of resemble,to
R8298 T10754 T10751 arg2Of sites,resemble
R8299 T10754 T10752 arg1Of sites,CREB
R8300 T10754 T10753 arg1Of sites,binding
R8301 T10755 T10764 arg1Of ",",and
R8302 T10756 T10755 arg2Of bind,","
R8303 T10756 T10759 arg1Of bind,vitro
R8304 T10756 T10762 arg1Of bind,vivo
R8305 T10757 T10756 arg2Of CREB,bind
R8306 T10759 T10758 arg1Of vitro,in
R8307 T10759 T10760 arg1Of vitro,and
R8308 T10762 T10760 arg2Of vivo,and
R8309 T10762 T10761 arg1Of vivo,in
R8310 T10764 T10763 arg1Of and,","
R8311 T10764 T10779 arg1Of and,[
R8312 T10765 T10764 arg2Of facilitate,and
R8313 T10765 T10770 arg1Of facilitate,in
R8314 T10765 T10774 arg1Of facilitate,in
R8315 T10768 T10765 arg2Of activation,facilitate
R8316 T10768 T10766 arg1Of activation,HTLV-I
R8317 T10768 T10767 arg1Of activation,LTR
R8318 T10770 T10773 arg1Of in,and
R8319 T10772 T10770 arg2Of presence,in
R8320 T10772 T10771 arg1Of presence,the
R8321 T10773 T10769 arg1Of and,both
R8322 T10774 T10773 arg2Of in,and
R8323 T10776 T10774 arg2Of absence,in
R8324 T10776 T10775 arg1Of absence,the
R8325 T10776 T10777 arg1Of absence,of
R8326 T10778 T10777 arg2Of Tax,of
R8327 T10780 T10779 arg2Of "35,36",[
R8328 T10781 T10779 arg3Of ],[
R8329 T10782 T10783 arg1Of Ching,and
R8330 T10783 T10788 arg1Of and,demonstrated
R8331 T10784 T10783 arg2Of colleagues,and
R8332 T10784 T10785 arg1Of colleagues,[
R8333 T10786 T10785 arg2Of 18,[
R8334 T10787 T10785 arg3Of ],[
R8335 T10790 T10791 arg1Of addition,of
R8336 T10790 T10797 arg1Of addition,resulted
R8337 T10796 T10791 arg2Of vector,of
R8338 T10796 T10792 arg1Of vector,a
R8339 T10796 T10793 arg1Of vector,dominant-negative
R8340 T10796 T10794 arg1Of vector,CREB
R8341 T10796 T10795 arg1Of vector,expression
R8342 T10797 T10788 arg2Of resulted,demonstrated
R8343 T10797 T10789 arg1Of resulted,that
R8344 T10797 T10798 arg1Of resulted,in
R8345 T10797 T10809 arg1Of resulted,","
R8346 T10797 T10810 arg1Of resulted,while
R8347 T10800 T10799 arg1Of complete,nearly
R8348 T10801 T10798 arg2Of inhibition,in
R8349 T10801 T10800 arg1Of inhibition,complete
R8350 T10801 T10802 arg1Of inhibition,of
R8351 T10804 T10802 arg2Of activation,of
R8352 T10804 T10803 arg1Of activation,Tax-mediated
R8353 T10804 T10805 arg1Of activation,of
R8354 T10808 T10805 arg2Of LTR,of
R8355 T10808 T10806 arg1Of LTR,the
R8356 T10808 T10807 arg1Of LTR,HTLV-I
R8357 T10813 T10811 arg1Of activation,blocking
R8358 T10813 T10812 arg1Of activation,NF-κB
R8359 T10813 T10814 arg1Of activation,by
R8360 T10813 T10822 arg1Of activation,had
R8361 T10815 T10814 arg2Of addition,by
R8362 T10815 T10816 arg1Of addition,of
R8363 T10821 T10816 arg2Of vector,of
R8364 T10821 T10817 arg1Of vector,a
R8365 T10821 T10818 arg1Of vector,dominant-negative
R8366 T10821 T10819 arg1Of vector,IKKβ
R8367 T10821 T10820 arg1Of vector,expression
R8368 T10822 T10810 arg2Of had,while
R8369 T10822 T10825 arg1Of had,on
R8370 T10824 T10822 arg2Of effect,had
R8371 T10824 T10823 arg1Of effect,no
R8372 T10827 T10825 arg2Of transactivation,on
R8373 T10827 T10826 arg1Of transactivation,Tax
R8374 T10827 T10828 arg1Of transactivation,of
R8375 T10831 T10828 arg2Of LTR,of
R8376 T10831 T10829 arg1Of LTR,the
R8377 T10831 T10830 arg1Of LTR,HTLV-I
R8378 T10834 T10835 arg1Of we,hypothesized
R8379 T10835 T10832 arg1Of hypothesized,Therefore
R8380 T10835 T10833 arg1Of hypothesized,","
R8381 T10837 T10838 arg1Of Foxp3,may
R8382 T10837 T10839 arg1Of Foxp3,inhibit
R8383 T10839 T10835 arg2Of inhibit,hypothesized
R8384 T10839 T10836 arg1Of inhibit,that
R8385 T10839 T10838 arg2Of inhibit,may
R8386 T10839 T10846 arg1Of inhibit,via
R8387 T10841 T10839 arg2Of transactivation,inhibit
R8388 T10841 T10840 arg1Of transactivation,Tax
R8389 T10841 T10842 arg1Of transactivation,of
R8390 T10845 T10842 arg2Of LTR,of
R8391 T10845 T10843 arg1Of LTR,the
R8392 T10845 T10844 arg1Of LTR,HTLV-I
R8393 T10847 T10846 arg2Of disruption,via
R8394 T10847 T10848 arg1Of disruption,of
R8395 T10852 T10848 arg2Of pathway,of
R8396 T10852 T10849 arg1Of pathway,the
R8397 T10852 T10850 arg1Of pathway,CREB
R8398 T10852 T10851 arg1Of pathway,signaling
R8399 T10854 T10853 arg1Of test,To
R8400 T10856 T10854 arg2Of possibility,test
R8401 T10856 T10855 arg1Of possibility,this
R8402 T10860 T10854 arg1Of cells,test
R8403 T10860 T10858 arg1Of cells,HEK
R8404 T10860 T10859 arg1Of cells,293T
R8405 T10860 T10861 arg1Of cells,were
R8406 T10860 T10862 arg2Of cells,transfected
R8407 T10862 T10853 modOf transfected,To
R8408 T10862 T10857 arg1Of transfected,","
R8409 T10862 T10861 arg2Of transfected,were
R8410 T10862 T10863 arg1Of transfected,with
R8411 T10862 T10873 arg1Of transfected,with
R8412 T10866 T10864 arg1Of LTR,an
R8413 T10866 T10865 arg1Of LTR,HTLV-I
R8414 T10866 T10867 arg1Of LTR,or
R8415 T10867 T10863 arg2Of or,with
R8416 T10871 T10867 arg2Of vector,or
R8417 T10871 T10868 arg1Of vector,synthetic
R8418 T10871 T10869 arg1Of vector,CREB
R8419 T10871 T10870 arg1Of vector,reporter
R8420 T10873 T10872 arg1Of with,along
R8421 T10877 T10874 arg1Of vector,a
R8422 T10877 T10875 arg1Of vector,control
R8423 T10877 T10876 arg1Of vector,expression
R8424 T10877 T10878 arg1Of vector,(
R8425 T10877 T10881 arg1Of vector,or
R8426 T10879 T10878 arg2Of EGFP,(
R8427 T10880 T10878 arg3Of ),(
R8428 T10881 T10873 arg2Of or,with
R8429 T10883 T10881 arg2Of vectors,or
R8430 T10883 T10882 arg1Of vectors,expression
R8431 T10883 T10884 arg1Of vectors,encoding
R8432 T10885 T10886 arg1Of Foxp3,or
R8433 T10886 T10884 arg2Of or,encoding
R8434 T10887 T10886 arg2Of ΔFKH,or
R8435 T10889 T10888 arg2Of shown,As
R8436 T10889 T10890 arg1Of shown,in
R8437 T10892 T10890 arg2Of 6A,in
R8438 T10892 T10891 arg1Of 6A,Figure
R8439 T10894 T10895 arg1Of Foxp3,down-regulated
R8440 T10895 T10888 arg1Of down-regulated,As
R8441 T10895 T10893 arg1Of down-regulated,","
R8442 T10895 T10910 arg1Of down-regulated,","
R8443 T10895 T10911 modOf down-regulated,suggesting
R8444 T10897 T10896 arg1Of activation,basal
R8445 T10897 T10898 arg1Of activation,of
R8446 T10897 T10902 arg1Of activation,and
R8447 T10901 T10898 arg2Of LTR,of
R8448 T10901 T10899 arg1Of LTR,the
R8449 T10901 T10900 arg1Of LTR,HTLV-I
R8450 T10902 T10895 arg2Of and,down-regulated
R8451 T10903 T10902 arg2Of transcription,and
R8452 T10903 T10904 arg1Of transcription,of
R8453 T10909 T10904 arg2Of vector,of
R8454 T10909 T10905 arg1Of vector,a
R8455 T10909 T10906 arg1Of vector,synthetic
R8456 T10909 T10907 arg1Of vector,CREB
R8457 T10909 T10908 arg1Of vector,reporter
R8458 T10913 T10914 arg1Of Foxp3,down-regulates
R8459 T10913 T10919 arg1Of Foxp3,targeting
R8460 T10914 T10911 arg2Of down-regulates,suggesting
R8461 T10914 T10912 arg1Of down-regulates,that
R8462 T10914 T10918 arg1Of down-regulates,by
R8463 T10917 T10914 arg2Of activation,down-regulates
R8464 T10917 T10915 arg1Of activation,HTLV-I
R8465 T10917 T10916 arg1Of activation,LTR
R8466 T10919 T10918 arg2Of targeting,by
R8467 T10922 T10919 arg2Of pathway,targeting
R8468 T10922 T10920 arg1Of pathway,the
R8469 T10922 T10921 arg1Of pathway,CREB
R8470 T10923 T10924 arg1Of Deletion,of
R8471 T10923 T10930 arg1Of Deletion,dampened
R8472 T10923 T10938 arg1Of Deletion,did
R8473 T10923 T10941 arg1Of Deletion,abrogate
R8474 T10927 T10924 arg2Of domain,of
R8475 T10927 T10925 arg1Of domain,the
R8476 T10927 T10926 arg1Of domain,FKH
R8477 T10927 T10928 arg1Of domain,of
R8478 T10929 T10928 arg2Of Foxp3,of
R8479 T10930 T10937 arg1Of dampened,but
R8480 T10933 T10930 arg2Of effect,dampened
R8481 T10933 T10931 arg1Of effect,the
R8482 T10933 T10932 arg1Of effect,suppressive
R8483 T10933 T10934 arg1Of effect,of
R8484 T10935 T10934 arg2Of Foxp3,of
R8485 T10937 T10936 arg1Of but,","
R8486 T10937 T10943 arg1Of but,","
R8487 T10937 T10944 arg1Of but,as
R8488 T10941 T10937 arg2Of abrogate,but
R8489 T10941 T10938 arg2Of abrogate,did
R8490 T10941 T10939 arg1Of abrogate,not
R8491 T10941 T10940 arg1Of abrogate,completely
R8492 T10942 T10941 arg2Of suppression,abrogate
R8493 T10946 T10944 arg2Of seen,as
R8494 T10946 T10945 arg2Of seen,is
R8495 T10946 T10947 arg1Of seen,with
R8496 T10949 T10947 arg2Of promoters,with
R8497 T10949 T10948 arg1Of promoters,NF-κB-responsive
R8498 T10949 T10950 arg1Of promoters,in
R8499 T10953 T10950 arg2Of cells,in
R8500 T10953 T10951 arg1Of cells,HEK
R8501 T10953 T10952 arg1Of cells,293T
R8502 T10956 T10954 arg2Of activation,Like
R8503 T10956 T10955 arg1Of activation,NF-κB
R8504 T10960 T10958 arg1Of activation,CREB
R8505 T10960 T10959 arg1Of activation,transcriptional
R8506 T10960 T10961 arg1Of activation,was
R8507 T10960 T10963 arg2Of activation,suppressed
R8508 T10963 T10954 arg1Of suppressed,Like
R8509 T10963 T10957 arg1Of suppressed,","
R8510 T10963 T10961 arg2Of suppressed,was
R8511 T10963 T10962 arg1Of suppressed,also
R8512 T10963 T10975 arg1Of suppressed,","
R8513 T10963 T10976 arg1Of suppressed,in
R8514 T10965 T10963 arg1Of expression,suppressed
R8515 T10965 T10964 arg2Of expression,by
R8516 T10965 T10966 arg1Of expression,of
R8517 T10965 T10970 arg1Of expression,to
R8518 T10966 T10969 arg1Of of,and
R8519 T10967 T10966 arg2Of Foxp3,of
R8520 T10969 T10968 arg1Of and,","
R8521 T10970 T10969 arg2Of to,and
R8522 T10974 T10970 arg2Of ΔFKH,to
R8523 T10974 T10971 arg1Of ΔFKH,a
R8524 T10974 T10972 arg1Of ΔFKH,similar
R8525 T10974 T10973 arg1Of ΔFKH,extent
R8526 T10981 T10976 arg2Of cells,in
R8527 T10981 T10977 arg1Of cells,healthy
R8528 T10981 T10978 arg1Of cells,donor
R8529 T10981 T10979 arg1Of cells,CD4+
R8530 T10981 T10980 arg1Of cells,T
R8531 T10981 T10982 arg1Of cells,(
R8532 T10984 T10982 arg2Of 6B,(
R8533 T10984 T10983 arg1Of 6B,Figure
R8534 T10985 T10982 arg3Of ),(
R8535 T10988 T10989 arg1Of Foxp3,and
R8536 T10989 T10992 arg1Of and,repressed
R8537 T10990 T10989 arg2Of ΔFKH,and
R8538 T10992 T10986 arg1Of repressed,Similarly
R8539 T10992 T10987 arg1Of repressed,","
R8540 T10992 T10991 arg1Of repressed,also
R8541 T10996 T10992 arg2Of activation,repressed
R8542 T10996 T10993 arg1Of activation,basal
R8543 T10996 T10994 arg1Of activation,HTLV-I
R8544 T10996 T10995 arg1Of activation,LTR
R8545 T10996 T10997 arg1Of activation,in
R8546 T11002 T10997 arg2Of cells,in
R8547 T11002 T10998 arg1Of cells,primary
R8548 T11002 T10999 arg1Of cells,human
R8549 T11002 T11000 arg1Of cells,CD4+
R8550 T11002 T11001 arg1Of cells,T
R8551 T11002 T11003 arg1Of cells,(
R8552 T11005 T11003 arg2Of 6C,(
R8553 T11005 T11004 arg1Of 6C,Figure
R8554 T11006 T11003 arg3Of ),(
R8555 T11009 T11007 arg2Of knowledge,To
R8556 T11009 T11008 arg1Of knowledge,our
R8557 T11011 T11012 arg1Of this,is
R8558 T11012 T11007 arg1Of is,To
R8559 T11012 T11010 arg1Of is,","
R8560 T11015 T11012 arg2Of evidence,is
R8561 T11015 T11013 arg1Of evidence,the
R8562 T11015 T11014 arg1Of evidence,first
R8563 T11015 T11016 arg1Of evidence,implicating
R8564 T11016 T11018 arg1Of implicating,as
R8565 T11017 T11016 arg2Of CREB,implicating
R8566 T11021 T11018 arg2Of target,as
R8567 T11021 T11019 arg1Of target,a
R8568 T11021 T11020 arg1Of target,molecular
R8569 T11021 T11022 arg1Of target,of
R8570 T11023 T11022 arg2Of Foxp3,of
R8571 T11025 T11024 arg2Of observed,As
R8572 T11025 T11026 arg1Of observed,with
R8573 T11028 T11026 arg2Of activation,with
R8574 T11028 T11027 arg1Of activation,NF-κB
R8575 T11030 T11031 arg1Of ΔFKH,was
R8576 T11031 T11024 arg1Of was,As
R8577 T11031 T11029 arg1Of was,","
R8578 T11031 T11043 arg1Of was,than
R8579 T11031 T11048 arg1Of was,","
R8580 T11031 T11050 modOf was,indicating
R8581 T11034 T11033 arg1Of potent,more
R8582 T11035 T11031 arg2Of inhibitor,was
R8583 T11035 T11032 arg1Of inhibitor,a
R8584 T11035 T11034 arg1Of inhibitor,potent
R8585 T11035 T11036 arg1Of inhibitor,of
R8586 T11038 T11036 arg2Of activation,of
R8587 T11038 T11037 arg1Of activation,CREB
R8588 T11038 T11039 arg1Of activation,in
R8589 T11042 T11039 arg2Of cells,in
R8590 T11042 T11040 arg1Of cells,CD4+
R8591 T11042 T11041 arg1Of cells,T
R8592 T11044 T11043 arg2Of in,than
R8593 T11047 T11044 arg2Of cells,in
R8594 T11047 T11045 arg1Of cells,HEK
R8595 T11047 T11046 arg1Of cells,293T
R8596 T11050 T11049 arg1Of indicating,further
R8597 T11054 T11053 arg1Of type-specific,cell
R8598 T11055 T11052 arg1Of mechanism,a
R8599 T11055 T11054 arg1Of mechanism,type-specific
R8600 T11055 T11056 arg1Of mechanism,of
R8601 T11055 T11058 arg1Of mechanism,may
R8602 T11055 T11059 arg1Of mechanism,govern
R8603 T11057 T11056 arg2Of action,of
R8604 T11059 T11050 arg2Of govern,indicating
R8605 T11059 T11051 arg1Of govern,that
R8606 T11059 T11058 arg2Of govern,may
R8607 T11061 T11059 arg2Of function,govern
R8608 T11061 T11060 arg1Of function,the
R8609 T11061 T11062 arg1Of function,of
R8610 T11065 T11062 arg2Of mutant,of
R8611 T11065 T11063 arg1Of mutant,this
R8612 T11065 T11064 arg1Of mutant,Foxp3
R8613 T11067 T11066 arg1Of determine,To
R8614 T11067 T11069 arg1Of determine,Foxp3
R8615 T11067 T11070 arg1Of determine,functioned
R8616 T11069 T11068 arg2Of Foxp3,whether
R8617 T11070 T11068 arg1Of functioned,whether
R8618 T11070 T11071 arg1Of functioned,by
R8619 T11073 T11071 arg2Of signaling,by
R8620 T11073 T11072 arg1Of signaling,directly
R8621 T11073 T11074 arg1Of signaling,through
R8622 T11075 T11074 arg2Of CREB,through
R8623 T11077 T11078 arg1Of we,utilized
R8624 T11078 T11070 arg2Of utilized,functioned
R8625 T11078 T11076 arg1Of utilized,","
R8626 T11080 T11078 arg2Of vectors,utilized
R8627 T11080 T11079 arg1Of vectors,expression
R8628 T11080 T11081 arg1Of vectors,encoding
R8629 T11082 T11083 arg1Of CREB-1,or
R8630 T11083 T11081 arg2Of or,encoding
R8631 T11083 T11085 arg1Of or,(
R8632 T11083 T11098 arg2Of or,fused
R8633 T11084 T11083 arg2Of c-Jun,or
R8634 T11087 T11085 arg2Of member,(
R8635 T11087 T11086 arg1Of member,a
R8636 T11087 T11088 arg1Of member,of
R8637 T11093 T11088 arg2Of family,of
R8638 T11093 T11089 arg1Of family,the
R8639 T11093 T11090 arg1Of family,activator
R8640 T11093 T11091 arg1Of family,protein
R8641 T11093 T11092 arg1Of family,1
R8642 T11093 T11094 arg1Of family,of
R8643 T11096 T11094 arg2Of factors,of
R8644 T11096 T11095 arg1Of factors,transcription
R8645 T11097 T11085 arg3Of ),(
R8646 T11098 T11100 arg1Of fused,to
R8647 T11100 T11099 arg1Of to,in-frame
R8648 T11102 T11100 arg2Of Gal4-BD,to
R8649 T11102 T11101 arg1Of Gal4-BD,the
R8650 T11102 T11103 arg1Of Gal4-BD,(
R8651 T11104 T11105 arg1Of Gal4-BD-CREB-1,and
R8652 T11105 T11103 arg2Of and,(
R8653 T11106 T11105 arg2Of Gal4-BD-c-Jun,and
R8654 T11107 T11103 arg3Of ),(
R8655 T11109 T11108 arg2Of shown,As
R8656 T11109 T11110 arg1Of shown,in
R8657 T11112 T11110 arg2Of 6D,in
R8658 T11112 T11111 arg1Of 6D,Figure
R8659 T11114 T11115 arg1Of activation,of
R8660 T11114 T11120 arg1Of activation,by
R8661 T11114 T11122 arg1Of activation,was
R8662 T11114 T11123 arg2Of activation,down-regulated
R8663 T11114 T11134 arg1Of activation,indicating
R8664 T11114 T11142 arg1Of activation,interacting
R8665 T11119 T11115 arg2Of vector,of
R8666 T11119 T11116 arg1Of vector,a
R8667 T11119 T11117 arg1Of vector,Gal4-responsive
R8668 T11119 T11118 arg1Of vector,reporter
R8669 T11121 T11120 arg2Of Gal4-BD-CREB-1,by
R8670 T11123 T11108 arg1Of down-regulated,As
R8671 T11123 T11113 arg1Of down-regulated,","
R8672 T11123 T11122 arg2Of down-regulated,was
R8673 T11123 T11126 arg1Of down-regulated,compared
R8674 T11123 T11133 arg1Of down-regulated,","
R8675 T11123 T11134 modOf down-regulated,indicating
R8676 T11123 T11142 modOf down-regulated,interacting
R8677 T11125 T11123 arg1Of Foxp3,down-regulated
R8678 T11125 T11124 arg2Of Foxp3,by
R8679 T11127 T11126 arg2Of to,compared
R8680 T11129 T11127 arg2Of vector,to
R8681 T11129 T11128 arg1Of vector,control
R8682 T11129 T11130 arg1Of vector,(
R8683 T11131 T11130 arg2Of EGFP,(
R8684 T11132 T11130 arg3Of ),(
R8685 T11134 T11138 arg1Of indicating,by
R8686 T11134 T11140 arg1Of indicating,or
R8687 T11137 T11134 arg2Of functions,indicating
R8688 T11137 T11135 arg1Of functions,that
R8689 T11137 T11136 arg1Of functions,Foxp3
R8690 T11139 T11138 arg2Of directly,by
R8691 T11142 T11140 arg2Of interacting,or
R8692 T11142 T11141 arg1Of interacting,indirectly
R8693 T11142 T11143 arg1Of interacting,with
R8694 T11144 T11143 arg2Of CREB-1,with
R8695 T11147 T11148 arg1Of Foxp3,failed
R8696 T11147 T11151 arg1Of Foxp3,affect
R8697 T11148 T11145 arg1Of failed,However
R8698 T11148 T11146 arg1Of failed,","
R8699 T11151 T11148 arg2Of affect,failed
R8700 T11151 T11149 arg1Of affect,to
R8701 T11151 T11150 arg1Of affect,markedly
R8702 T11151 T11171 arg1Of affect,(
R8703 T11153 T11152 arg1Of activation,transcriptional
R8704 T11153 T11154 arg1Of activation,of
R8705 T11153 T11156 arg1Of activation,(
R8706 T11153 T11169 arg1Of activation,and
R8707 T11155 T11154 arg2Of Gal4-BD-c-Jun,of
R8708 T11157 T11158 arg1Of c-Jun,has
R8709 T11157 T11160 arg1Of c-Jun,been
R8710 T11157 T11161 arg2Of c-Jun,demonstrated
R8711 T11157 T11163 arg1Of c-Jun,bind
R8712 T11161 T11156 arg2Of demonstrated,(
R8713 T11161 T11158 arg2Of demonstrated,has
R8714 T11161 T11159 arg1Of demonstrated,also
R8715 T11161 T11160 arg2Of demonstrated,been
R8716 T11163 T11161 arg3Of bind,demonstrated
R8717 T11163 T11162 arg1Of bind,to
R8718 T11163 T11164 arg1Of bind,to
R8719 T11167 T11164 arg2Of LTR,to
R8720 T11167 T11165 arg1Of LTR,the
R8721 T11167 T11166 arg1Of LTR,HTLV-I
R8722 T11168 T11156 arg3Of ),(
R8723 T11169 T11151 arg2Of and,affect
R8724 T11170 T11169 arg2Of Gal4-BD-Tax,and
R8725 T11172 T11171 arg2Of see,(
R8726 T11173 T11172 arg2Of Figure,see
R8727 T11173 T11174 arg1Of Figure,5
R8728 T11175 T11171 arg3Of ),(
R8729 T11179 T11178 arg1Of mechanism,the
R8730 T11179 T11180 arg1Of mechanism,of
R8731 T11179 T11186 arg1Of mechanism,was
R8732 T11179 T11188 arg1Of mechanism,due
R8733 T11182 T11180 arg2Of inhibition,of
R8734 T11182 T11181 arg1Of inhibition,Foxp3-mediated
R8735 T11182 T11183 arg1Of inhibition,of
R8736 T11185 T11183 arg2Of transcription,of
R8737 T11185 T11184 arg1Of transcription,CREB-dependent
R8738 T11186 T11176 arg1Of was,Importantly
R8739 T11186 T11177 arg1Of was,","
R8740 T11186 T11187 arg1Of was,not
R8741 T11186 T11196 arg1Of was,","
R8742 T11188 T11186 arg2Of due,was
R8743 T11188 T11189 arg1Of due,to
R8744 T11191 T11189 arg2Of block,to
R8745 T11191 T11190 arg1Of block,a
R8746 T11191 T11192 arg1Of block,in
R8747 T11195 T11192 arg2Of expression,in
R8748 T11195 T11193 arg1Of expression,CREB-1
R8749 T11195 T11194 arg1Of expression,protein
R8750 T11197 T11186 arg3Of as,was
R8751 T11198 T11197 arg2Of determined,as
R8752 T11198 T11199 arg1Of determined,by
R8753 T11202 T11199 arg2Of analysis,by
R8754 T11202 T11200 arg1Of analysis,Western
R8755 T11202 T11201 arg1Of analysis,blot
R8756 T11202 T11203 arg1Of analysis,(
R8757 T11205 T11203 arg2Of 6E,(
R8758 T11205 T11204 arg1Of 6E,Figure
R8759 T11206 T11203 arg3Of ),(
R8760 T11209 T11208 arg1Of results,these
R8761 T11209 T11210 arg1Of results,demonstrate
R8762 T11210 T11207 arg2Of demonstrate,Although
R8763 T11212 T11213 arg1Of Foxp3,functions
R8764 T11213 T11210 arg2Of functions,demonstrate
R8765 T11213 T11211 arg1Of functions,that
R8766 T11213 T11214 arg1Of functions,as
R8767 T11216 T11214 arg2Of co-repressor,as
R8768 T11216 T11215 arg1Of co-repressor,a
R8769 T11216 T11217 arg1Of co-repressor,of
R8770 T11219 T11217 arg2Of activation,of
R8771 T11219 T11218 arg1Of activation,CREB
R8772 T11219 T11220 arg1Of activation,(
R8773 T11221 T11220 arg2Of in,(
R8774 T11222 T11221 arg2Of addition,in
R8775 T11222 T11223 arg1Of addition,to
R8776 T11224 T11225 arg1Of NF-κB,and
R8777 T11225 T11223 arg2Of and,to
R8778 T11226 T11225 arg2Of NF-AT,and
R8779 T11227 T11220 arg3Of ),(
R8780 T11229 T11230 arg1Of we,were
R8781 T11229 T11231 arg1Of we,unable
R8782 T11229 T11233 arg1Of we,detect
R8783 T11230 T11207 arg1Of were,Although
R8784 T11230 T11228 arg1Of were,","
R8785 T11231 T11230 arg2Of unable,were
R8786 T11233 T11231 arg2Of detect,unable
R8787 T11233 T11232 arg1Of detect,to
R8788 T11237 T11233 arg2Of interaction,detect
R8789 T11237 T11234 arg1Of interaction,a
R8790 T11237 T11235 arg1Of interaction,direct
R8791 T11237 T11236 arg1Of interaction,physical
R8792 T11237 T11238 arg1Of interaction,between
R8793 T11239 T11240 arg1Of CREB-1,and
R8794 T11240 T11242 arg1Of and,by
R8795 T11240 T11244 arg1Of and,or
R8796 T11241 T11240 arg2Of Foxp3,and
R8797 T11243 T11242 arg2Of coimmunoprecipitation,by
R8798 T11244 T11238 arg2Of or,between
R8799 T11247 T11244 arg2Of analysis,or
R8800 T11247 T11245 arg1Of analysis,mammalian
R8801 T11247 T11246 arg1Of analysis,two-hybrid
R8802 T11247 T11248 arg1Of analysis,(
R8803 T11250 T11248 arg2Of data,(
R8804 T11250 T11249 arg1Of data,unpublished
R8805 T11251 T11248 arg3Of ),(
R8806 T11255 T11254 arg1Of data,our
R8807 T11255 T11256 arg1Of data,suggest
R8808 T11256 T11252 arg1Of suggest,Therefore
R8809 T11256 T11253 arg1Of suggest,","
R8810 T11258 T11259 arg1Of Foxp3,may
R8811 T11258 T11260 arg1Of Foxp3,interfere
R8812 T11260 T11256 arg2Of interfere,suggest
R8813 T11260 T11257 arg1Of interfere,that
R8814 T11260 T11259 arg2Of interfere,may
R8815 T11260 T11261 arg1Of interfere,with
R8816 T11263 T11261 arg2Of signaling,with
R8817 T11263 T11262 arg1Of signaling,CREB
R8818 T11263 T11264 arg1Of signaling,at
R8819 T11263 T11268 arg1Of signaling,","
R8820 T11263 T11270 arg1Of signaling,as
R8821 T11267 T11264 arg2Of event,at
R8822 T11267 T11265 arg1Of event,an
R8823 T11267 T11266 arg1Of event,upstream
R8824 T11270 T11269 arg1Of as,such
R8825 T11271 T11270 arg2Of phosphorylation,as
R8826 T11271 T11272 arg1Of phosphorylation,of
R8827 T11273 T11274 arg1Of CREB,or
R8828 T11274 T11272 arg2Of or,of
R8829 T11274 T11276 arg1Of or,of
R8830 T11274 T11284 arg1Of or,/p300
R8831 T11275 T11274 arg2Of recruitment/function,or
R8832 T11280 T11276 arg2Of protein,of
R8833 T11280 T11277 arg1Of protein,coactivator
R8834 T11280 T11278 arg1Of protein,proteins
R8835 T11280 T11279 arg1Of protein,CREB-binding
R8836 T11280 T11281 arg1Of protein,(
R8837 T11282 T11281 arg2Of CBP,(
R8838 T11283 T11281 arg3Of ),(
R9683 T12825 T12826 arg1Of Foxp3,Antagonizes
R9684 T12829 T12828 arg1Of Activation,Transcriptional
R9685 T12829 T12826 arg2Of Activation,Antagonizes
R9686 T12829 T12827 arg1Of Activation,CREB
R9687 T12829 T12830 arg1Of Activation,by
R9688 T12833 T12830 arg2Of Recruitment,by
R9689 T12833 T12831 arg1Of Recruitment,Disrupting
R9690 T12833 T12832 arg1Of Recruitment,Coactivator
R9691 T12834 T12835 arg1Of Stimulation,of
R9692 T12834 T12838 arg1Of Stimulation,by
R9693 T12834 T12853 arg1Of Stimulation,increase
R9694 T12837 T12835 arg2Of transcription,of
R9695 T12837 T12836 arg1Of transcription,CREB-dependent
R9696 T12839 T12838 arg2Of reagents,by
R9697 T12839 T12840 arg1Of reagents,that
R9698 T12839 T12841 arg1Of reagents,activate
R9699 T12839 T12845 arg1Of reagents,increase
R9700 T12841 T12844 arg1Of activate,and
R9701 T12843 T12841 arg2Of cyclase,activate
R9702 T12843 T12842 arg1Of cyclase,adenylate
R9703 T12845 T12844 arg2Of increase,and
R9704 T12847 T12845 arg2Of levels,increase
R9705 T12847 T12846 arg1Of levels,cAMP
R9706 T12847 T12848 arg1Of levels,(
R9707 T12851 T12848 arg2Of forskolin,(
R9708 T12851 T12849 arg1Of forskolin,e.g.
R9709 T12851 T12850 arg1Of forskolin,","
R9710 T12852 T12848 arg3Of ),(
R9711 T12853 T12859 arg1Of increase,through
R9712 T12856 T12853 arg2Of potential,increase
R9713 T12856 T12854 arg1Of potential,the
R9714 T12856 T12855 arg1Of potential,transactivation
R9715 T12856 T12857 arg1Of potential,of
R9716 T12858 T12857 arg2Of CREB,of
R9717 T12860 T12859 arg2Of phosphorylation,through
R9718 T12860 T12861 arg1Of phosphorylation,of
R9719 T12862 T12861 arg2Of serine,of
R9720 T12862 T12863 arg1Of serine,133
R9721 T12862 T12864 arg1Of serine,by
R9722 T12862 T12868 arg1Of serine,","
R9723 T12862 T12869 arg1Of serine,which
R9724 T12862 T12870 arg1Of serine,permits
R9725 T12867 T12864 arg2Of A,by
R9726 T12867 T12865 arg1Of A,protein
R9727 T12867 T12866 arg1Of A,kinase
R9728 T12870 T12880 arg1Of permits,[
R9729 T12871 T12872 arg1Of binding,and
R9730 T12872 T12870 arg2Of and,permits
R9731 T12872 T12874 arg1Of and,of
R9732 T12872 T12877 arg1Of and,to
R9733 T12873 T12872 arg2Of recruitment,and
R9734 T12876 T12874 arg2Of CBP/p300,of
R9735 T12876 T12875 arg1Of CBP/p300,coactivators
R9736 T12879 T12877 arg2Of promoter,to
R9737 T12879 T12878 arg1Of promoter,the
R9738 T12881 T12880 arg2Of "37,38",[
R9739 T12882 T12880 arg3Of ],[
R9740 T12883 T12884 arg1Of Phosphorylation,of
R9741 T12883 T12887 arg1Of Phosphorylation,does
R9742 T12883 T12892 arg1Of Phosphorylation,affect
R9743 T12885 T12884 arg2Of serine,of
R9744 T12885 T12886 arg1Of serine,133
R9745 T12892 T12887 arg2Of affect,does
R9746 T12892 T12888 arg1Of affect,not
R9747 T12892 T12889 arg1Of affect,","
R9748 T12892 T12890 arg1Of affect,however
R9749 T12892 T12891 arg1Of affect,","
R9750 T12892 T12898 arg1Of affect,in
R9751 T12895 T12892 arg2Of activity,affect
R9752 T12895 T12893 arg1Of activity,the
R9753 T12895 T12894 arg1Of activity,DNA-binding
R9754 T12895 T12896 arg1Of activity,of
R9755 T12897 T12896 arg2Of CREB,of
R9756 T12900 T12898 arg2Of cases,in
R9757 T12900 T12899 arg1Of cases,most
R9758 T12900 T12901 arg1Of cases,[
R9759 T12902 T12901 arg2Of 39–41,[
R9760 T12903 T12901 arg3Of ],[
R9761 T12904 T12905 arg1Of Addition,of
R9762 T12904 T12907 arg1Of Addition,to
R9763 T12904 T12911 arg1Of Addition,stimulated
R9764 T12906 T12905 arg2Of forskolin,of
R9765 T12910 T12907 arg2Of cells,to
R9766 T12910 T12908 arg1Of cells,HEK
R9767 T12910 T12909 arg1Of cells,293T
R9768 T12912 T12911 arg2Of activation,stimulated
R9769 T12912 T12913 arg1Of activation,of
R9770 T12919 T12918 arg1Of 65,about
R9771 T12920 T12913 arg2Of fold,of
R9772 T12920 T12914 arg1Of fold,a
R9773 T12920 T12915 arg1Of fold,CREB
R9774 T12920 T12916 arg1Of fold,reporter
R9775 T12920 T12917 arg1Of fold,vector
R9776 T12920 T12919 arg1Of fold,65
R9777 T12920 T12921 arg1Of fold,(
R9778 T12923 T12921 arg2Of 7A,(
R9779 T12923 T12922 arg1Of 7A,Figure
R9780 T12924 T12921 arg3Of ),(
R9781 T12925 T12926 arg1Of Overexpression,of
R9782 T12925 T12928 arg1Of Overexpression,was
R9783 T12925 T12929 arg1Of Overexpression,capable
R9784 T12925 T12931 arg1Of Overexpression,down-regulating
R9785 T12927 T12926 arg2Of Foxp3,of
R9786 T12929 T12928 arg2Of capable,was
R9787 T12929 T12930 arg1Of capable,of
R9788 T12931 T12930 arg2Of down-regulating,of
R9789 T12935 T12931 arg2Of activation,down-regulating
R9790 T12935 T12932 arg1Of activation,forskolin-induced
R9791 T12935 T12933 arg1Of activation,CREB
R9792 T12935 T12934 arg1Of activation,transcriptional
R9793 T12938 T12936 arg1Of interaction,The
R9794 T12938 T12937 arg1Of interaction,functional
R9795 T12938 T12939 arg1Of interaction,between
R9796 T12938 T12943 arg1Of interaction,did
R9797 T12938 T12945 arg1Of interaction,affect
R9798 T12938 T12953 arg1Of interaction,did
R9799 T12938 T12954 arg1Of interaction,show
R9800 T12940 T12941 arg1Of Foxp3,and
R9801 T12941 T12939 arg2Of and,between
R9802 T12942 T12941 arg2Of CREB,and
R9803 T12945 T12943 arg2Of affect,did
R9804 T12945 T12944 arg1Of affect,not
R9805 T12945 T12952 arg1Of affect,but
R9806 T12948 T12945 arg2Of activity,affect
R9807 T12948 T12946 arg1Of activity,the
R9808 T12948 T12947 arg1Of activity,DNA-binding
R9809 T12948 T12949 arg1Of activity,of
R9810 T12950 T12949 arg2Of CREB-1,of
R9811 T12952 T12951 arg1Of but,","
R9812 T12954 T12952 arg2Of show,but
R9813 T12954 T12953 arg2Of show,did
R9814 T12954 T12958 arg1Of show,in
R9815 T12957 T12954 arg2Of decrease,show
R9816 T12957 T12955 arg1Of decrease,a
R9817 T12957 T12956 arg1Of decrease,modest
R9818 T12959 T12958 arg2Of activating,in
R9819 T12959 T12968 arg1Of activating,in
R9820 T12959 T12973 arg1Of activating,as
R9821 T12964 T12963 arg2Of ATF-2,(
R9822 T12965 T12963 arg3Of ),(
R9823 T12967 T12959 arg2Of activity,activating
R9824 T12967 T12960 arg1Of activity,transcription
R9825 T12967 T12961 arg1Of activity,factor
R9826 T12967 T12962 arg1Of activity,2
R9827 T12967 T12963 arg1Of activity,(
R9828 T12967 T12966 arg1Of activity,DNA-binding
R9829 T12970 T12968 arg2Of presence,in
R9830 T12970 T12969 arg1Of presence,the
R9831 T12970 T12971 arg1Of presence,of
R9832 T12972 T12971 arg2Of forskolin,of
R9833 T12974 T12973 arg2Of determined,as
R9834 T12978 T12974 arg1Of ELISA,determined
R9835 T12978 T12975 arg2Of ELISA,by
R9836 T12978 T12976 arg1Of ELISA,transcription
R9837 T12978 T12977 arg1Of ELISA,factor
R9838 T12978 T12979 arg1Of ELISA,(
R9839 T12981 T12979 arg2Of 7B,(
R9840 T12981 T12980 arg1Of 7B,Figure
R9841 T12982 T12979 arg3Of ),(
R9842 T12984 T12985 arg1Of Foxp3,has
R9843 T12984 T12986 arg1Of Foxp3,been
R9844 T12984 T12987 arg2Of Foxp3,shown
R9845 T12984 T12989 arg1Of Foxp3,bind
R9846 T12984 T12992 arg1Of Foxp3,repress
R9847 T12987 T12983 arg2Of shown,While
R9848 T12987 T12985 arg2Of shown,has
R9849 T12987 T12986 arg2Of shown,been
R9850 T12989 T12990 arg1Of bind,to
R9851 T12989 T12991 arg1Of bind,and
R9852 T12991 T12987 arg3Of and,shown
R9853 T12991 T12988 arg1Of and,to
R9854 T12992 T12991 arg2Of repress,and
R9855 T12993 T12992 arg2Of activation,repress
R9856 T12993 T12994 arg1Of activation,of
R9857 T12996 T12997 arg1Of NF-κB,and
R9858 T12997 T12994 arg2Of and,of
R9859 T12997 T12995 arg1Of and,both
R9860 T12998 T12997 arg2Of NF-AT,and
R9861 T13003 T13002 arg1Of functions,Foxp3
R9862 T13003 T13004 modOf functions,to
R9863 T13003 T13009 arg1Of functions,has
R9864 T13003 T13011 arg1Of functions,been
R9865 T13003 T13012 arg2Of functions,elucidated
R9866 T13005 T13004 arg1Of bring,to
R9867 T13005 T13006 arg1Of bring,about
R9868 T13008 T13005 arg2Of affect,bring
R9869 T13008 T13007 arg1Of affect,this
R9870 T13012 T12983 arg1Of elucidated,While
R9871 T13012 T12999 arg1Of elucidated,","
R9872 T13012 T13000 arg1Of elucidated,exactly
R9873 T13012 T13001 arg1Of elucidated,how
R9874 T13012 T13009 arg2Of elucidated,has
R9875 T13012 T13010 arg1Of elucidated,not
R9876 T13012 T13011 arg2Of elucidated,been
R9877 T13014 T13013 arg1Of determine,To
R9878 T13015 T13014 arg2Of how,determine
R9879 T13016 T13017 arg1Of Foxp3,blocks
R9880 T13017 T13015 arg1Of blocks,how
R9881 T13019 T13017 arg2Of transcription,blocks
R9882 T13019 T13018 arg1Of transcription,CREB-dependent
R9883 T13021 T13022 arg1Of we,examined
R9884 T13022 T13013 modOf examined,To
R9885 T13022 T13020 arg1Of examined,","
R9886 T13024 T13025 arg1Of Foxp3,was
R9887 T13024 T13026 arg1Of Foxp3,capable
R9888 T13024 T13031 arg1Of Foxp3,disrupting
R9889 T13025 T13022 arg2Of was,examined
R9890 T13025 T13023 arg1Of was,whether
R9891 T13026 T13025 arg2Of capable,was
R9892 T13026 T13027 arg1Of capable,of
R9893 T13027 T13028 arg1Of of,(
R9894 T13029 T13028 arg2Of 1,(
R9895 T13030 T13028 arg3Of ),(
R9896 T13031 T13027 arg2Of disrupting,of
R9897 T13033 T13032 arg1Of recruitment,the
R9898 T13033 T13034 arg1Of recruitment,of
R9899 T13033 T13037 arg1Of recruitment,and/or
R9900 T13036 T13034 arg2Of proteins,of
R9901 T13036 T13035 arg1Of proteins,coactivator
R9902 T13037 T13031 arg2Of and/or,disrupting
R9903 T13039 T13038 arg1Of 2,(
R9904 T13039 T13040 arg1Of 2,)
R9905 T13041 T13039 arg1Of preventing,2
R9906 T13042 T13037 arg2Of phosphorylation,and/or
R9907 T13042 T13041 arg1Of phosphorylation,preventing
R9908 T13042 T13043 arg1Of phosphorylation,of
R9909 T13042 T13045 arg1Of phosphorylation,at
R9910 T13042 T13048 arg1Of phosphorylation,(
R9911 T13044 T13043 arg2Of CREB,of
R9912 T13046 T13045 arg2Of serine,at
R9913 T13046 T13047 arg1Of serine,133
R9914 T13049 T13048 arg2Of which,(
R9915 T13049 T13050 arg1Of which,is
R9916 T13052 T13050 arg2Of prerequisite,is
R9917 T13052 T13051 arg1Of prerequisite,a
R9918 T13052 T13053 arg1Of prerequisite,for
R9919 T13055 T13053 arg2Of recruitment,for
R9920 T13055 T13054 arg1Of recruitment,coactivator
R9921 T13056 T13048 arg3Of ),(
R9922 T13058 T13059 arg1Of both,of
R9923 T13058 T13062 arg1Of both,are
R9924 T13058 T13063 arg2Of both,required
R9925 T13061 T13059 arg2Of events,of
R9926 T13061 T13060 arg1Of events,these
R9927 T13063 T13057 arg2Of required,Since
R9928 T13063 T13062 arg2Of required,are
R9929 T13063 T13064 arg1Of required,for
R9930 T13067 T13064 arg2Of expression,for
R9931 T13067 T13065 arg1Of expression,CREB-dependent
R9932 T13067 T13066 arg1Of expression,gene
R9933 T13069 T13070 arg1Of we,hypothesized
R9934 T13070 T13057 arg1Of hypothesized,Since
R9935 T13070 T13068 arg1Of hypothesized,","
R9936 T13072 T13073 arg1Of Foxp3,may
R9937 T13072 T13074 arg1Of Foxp3,affect
R9938 T13074 T13070 arg2Of affect,hypothesized
R9939 T13074 T13071 arg1Of affect,that
R9940 T13074 T13073 arg2Of affect,may
R9941 T13074 T13077 arg1Of affect,at
R9942 T13076 T13074 arg2Of activation,affect
R9943 T13076 T13075 arg1Of activation,CREB
R9944 T13079 T13077 arg2Of steps,at
R9945 T13079 T13078 arg1Of steps,both
R9946 T13081 T13080 arg1Of determine,To
R9947 T13083 T13084 arg1Of Foxp3,can
R9948 T13083 T13085 arg1Of Foxp3,disrupt
R9949 T13085 T13081 arg2Of disrupt,determine
R9950 T13085 T13082 arg1Of disrupt,whether
R9951 T13085 T13084 arg2Of disrupt,can
R9952 T13087 T13085 arg2Of function/recruitment,disrupt
R9953 T13087 T13086 arg1Of function/recruitment,the
R9954 T13087 T13088 arg1Of function/recruitment,of
R9955 T13092 T13088 arg2Of p300,of
R9956 T13092 T13089 arg1Of p300,the
R9957 T13092 T13090 arg1Of p300,coactivator
R9958 T13092 T13091 arg1Of p300,protein
R9959 T13094 T13081 arg1Of we,determine
R9960 T13094 T13095 arg1Of we,introduced
R9961 T13095 T13080 modOf introduced,To
R9962 T13095 T13093 arg1Of introduced,","
R9963 T13095 T13105 arg1Of introduced,into
R9964 T13099 T13096 arg1Of vector,a
R9965 T13099 T13097 arg1Of vector,Gal4
R9966 T13099 T13098 arg1Of vector,reporter
R9967 T13099 T13100 arg1Of vector,and
R9968 T13100 T13095 arg2Of and,introduced
R9969 T13104 T13100 arg2Of vector,and
R9970 T13104 T13101 arg1Of vector,a
R9971 T13104 T13102 arg1Of vector,Gal4-BD-CREB-1
R9972 T13104 T13103 arg1Of vector,expression
R9973 T13108 T13105 arg2Of cells,into
R9974 T13108 T13106 arg1Of cells,HEK
R9975 T13108 T13107 arg1Of cells,293T
R9976 T13108 T13109 arg1Of cells,in
R9977 T13111 T13112 arg1Of absence,or
R9978 T13112 T13109 arg2Of or,in
R9979 T13112 T13110 arg1Of or,the
R9980 T13112 T13114 arg1Of or,of
R9981 T13113 T13112 arg2Of presence,or
R9982 T13115 T13116 arg1Of Foxp3,","
R9983 T13116 T13119 arg1Of ",",and/or
R9984 T13117 T13116 arg2Of p300,","
R9985 T13119 T13114 arg2Of and/or,of
R9986 T13119 T13118 arg1Of and/or,","
R9987 T13122 T13119 arg2Of vectors,and/or
R9988 T13122 T13120 arg1Of vectors,control
R9989 T13122 T13121 arg1Of vectors,expression
R9990 T13122 T13123 arg1Of vectors,(
R9991 T13125 T13123 arg2Of 7C,(
R9992 T13125 T13124 arg1Of 7C,Figure
R9993 T13126 T13123 arg3Of ),(
R9994 T13128 T13127 arg2Of expected,As
R9995 T13131 T13130 arg1Of overexpression,p300
R9996 T13131 T13132 arg1Of overexpression,stimulated
R9997 T13132 T13127 arg1Of stimulated,As
R9998 T13132 T13129 arg1Of stimulated,","
R9999 T13133 T13132 arg2Of transcription,stimulated