Id |
Subject |
Object |
Predicate |
Lexical cue |
T250 |
0-4 |
NN |
denotes |
Sox6 |
T251 |
5-13 |
NNP |
denotes |
Directly |
T252 |
14-22 |
NNP |
denotes |
Silences |
T253 |
23-30 |
NNP |
denotes |
Epsilon |
T254 |
31-37 |
NNP |
denotes |
Globin |
T255 |
38-48 |
NN |
denotes |
Expression |
T256 |
49-51 |
IN |
denotes |
in |
T257 |
52-62 |
JJ |
denotes |
Definitive |
T258 |
63-77 |
NN |
denotes |
Erythropoiesis |
T259 |
127-131 |
NN |
denotes |
Sox6 |
T260 |
132-134 |
VB |
denotes |
is |
T261 |
135-136 |
DT |
denotes |
a |
T262 |
137-143 |
NN |
denotes |
member |
T263 |
144-146 |
IN |
denotes |
of |
T264 |
147-150 |
DT |
denotes |
the |
T265 |
151-154 |
NN |
denotes |
Sox |
T266 |
155-168 |
NN |
denotes |
transcription |
T267 |
169-175 |
NN |
denotes |
factor |
T268 |
176-182 |
NN |
denotes |
family |
T269 |
183-187 |
WDT |
denotes |
that |
T270 |
188-190 |
VB |
denotes |
is |
T271 |
191-198 |
VB |
denotes |
defined |
T272 |
199-201 |
IN |
denotes |
by |
T273 |
202-205 |
DT |
denotes |
the |
T274 |
206-215 |
VB |
denotes |
conserved |
T275 |
216-220 |
JJ |
denotes |
high |
T276 |
221-229 |
NN |
denotes |
mobility |
T277 |
230-235 |
NN |
denotes |
group |
T278 |
236-237 |
-LRB- |
denotes |
( |
T279 |
237-240 |
NN |
denotes |
HMG |
T280 |
240-241 |
-RRB- |
denotes |
) |
T281 |
242-245 |
NN |
denotes |
DNA |
T282 |
246-253 |
NN |
denotes |
binding |
T283 |
254-260 |
NN |
denotes |
domain |
T284 |
260-261 |
-COMMA- |
denotes |
, |
T285 |
262-267 |
RB |
denotes |
first |
T286 |
268-277 |
VB |
denotes |
described |
T287 |
278-280 |
IN |
denotes |
in |
T288 |
281-284 |
DT |
denotes |
the |
T289 |
285-291 |
NN |
denotes |
testis |
T290 |
292-303 |
VB |
denotes |
determining |
T291 |
304-308 |
NN |
denotes |
gene |
T292 |
308-309 |
-COMMA- |
denotes |
, |
T293 |
310-314 |
NNP |
denotes |
Sry. |
T294 |
315-323 |
NNP |
denotes |
Previous |
T295 |
324-331 |
NN |
denotes |
studies |
T296 |
332-336 |
VB |
denotes |
have |
T297 |
337-346 |
VB |
denotes |
suggested |
T298 |
347-351 |
IN |
denotes |
that |
T299 |
352-356 |
NN |
denotes |
Sox6 |
T300 |
357-362 |
VB |
denotes |
plays |
T301 |
363-364 |
DT |
denotes |
a |
T302 |
365-369 |
NN |
denotes |
role |
T303 |
370-372 |
IN |
denotes |
in |
T304 |
373-376 |
DT |
denotes |
the |
T305 |
377-388 |
NN |
denotes |
development |
T306 |
389-391 |
IN |
denotes |
of |
T307 |
392-395 |
DT |
denotes |
the |
T308 |
396-403 |
JJ |
denotes |
central |
T309 |
404-411 |
JJ |
denotes |
nervous |
T310 |
412-418 |
NN |
denotes |
system |
T311 |
418-419 |
-COMMA- |
denotes |
, |
T312 |
420-429 |
NN |
denotes |
cartilage |
T313 |
429-430 |
-COMMA- |
denotes |
, |
T314 |
431-434 |
CC |
denotes |
and |
T315 |
435-441 |
NN |
denotes |
muscle |
T316 |
443-445 |
IN |
denotes |
In |
T317 |
446-449 |
DT |
denotes |
the |
T318 |
450-464 |
JJ |
denotes |
Sox6-deficient |
T319 |
465-470 |
NN |
denotes |
mouse |
T320 |
470-471 |
-COMMA- |
denotes |
, |
T321 |
472-477 |
NN |
denotes |
p100H |
T322 |
477-478 |
-COMMA- |
denotes |
, |
T323 |
479-481 |
JJ |
denotes |
ɛy |
T324 |
482-488 |
NN |
denotes |
globin |
T325 |
489-491 |
VB |
denotes |
is |
T326 |
492-504 |
RB |
denotes |
persistently |
T327 |
505-514 |
VB |
denotes |
expressed |
T328 |
514-515 |
-COMMA- |
denotes |
, |
T329 |
516-519 |
CC |
denotes |
and |
T330 |
520-529 |
VB |
denotes |
increased |
T331 |
530-537 |
NN |
denotes |
numbers |
T332 |
538-540 |
IN |
denotes |
of |
T333 |
541-550 |
JJ |
denotes |
nucleated |
T334 |
551-554 |
JJ |
denotes |
red |
T335 |
555-560 |
NN |
denotes |
cells |
T336 |
561-564 |
VB |
denotes |
are |
T337 |
565-572 |
JJ |
denotes |
present |
T338 |
573-575 |
IN |
denotes |
in |
T339 |
576-579 |
DT |
denotes |
the |
T340 |
580-585 |
JJ |
denotes |
fetal |
T341 |
586-597 |
NN |
denotes |
circulation |
T342 |
599-611 |
NN |
denotes |
Transfection |
T343 |
612-618 |
NN |
denotes |
assays |
T344 |
619-621 |
IN |
denotes |
in |
T345 |
622-627 |
NN |
denotes |
GM979 |
T346 |
628-629 |
-LRB- |
denotes |
( |
T347 |
629-644 |
JJ |
denotes |
erythroleukemic |
T348 |
644-645 |
-RRB- |
denotes |
) |
T349 |
646-651 |
NN |
denotes |
cells |
T350 |
652-658 |
VB |
denotes |
define |
T351 |
659-660 |
DT |
denotes |
a |
T352 |
661-668 |
NN |
denotes |
36–base |
T353 |
669-673 |
NN |
denotes |
pair |
T354 |
674-680 |
NN |
denotes |
region |
T355 |
681-683 |
IN |
denotes |
of |
T356 |
684-687 |
DT |
denotes |
the |
T357 |
688-690 |
JJ |
denotes |
ɛy |
T358 |
691-699 |
JJ |
denotes |
proximal |
T359 |
700-708 |
NN |
denotes |
promoter |
T360 |
709-713 |
WDT |
denotes |
that |
T361 |
714-716 |
VB |
denotes |
is |
T362 |
717-725 |
JJ |
denotes |
critical |
T363 |
726-729 |
IN |
denotes |
for |
T364 |
730-734 |
NN |
denotes |
Sox6 |
T365 |
735-743 |
VB |
denotes |
mediated |
T366 |
744-754 |
NN |
denotes |
repression |
T367 |
756-771 |
JJ |
denotes |
Electrophoretic |
T368 |
772-780 |
NN |
denotes |
mobility |
T369 |
781-786 |
NN |
denotes |
shift |
T370 |
787-792 |
NN |
denotes |
assay |
T371 |
793-794 |
-LRB- |
denotes |
( |
T372 |
794-798 |
NN |
denotes |
EMSA |
T373 |
798-799 |
-RRB- |
denotes |
) |
T374 |
800-803 |
CC |
denotes |
and |
T375 |
804-813 |
NN |
denotes |
chromatin |
T376 |
814-833 |
NN |
denotes |
immunoprecipitation |
T377 |
834-835 |
-LRB- |
denotes |
( |
T378 |
835-839 |
NN |
denotes |
ChIP |
T379 |
839-840 |
-RRB- |
denotes |
) |
T380 |
841-847 |
NN |
denotes |
assays |
T381 |
848-859 |
VB |
denotes |
demonstrate |
T382 |
860-864 |
IN |
denotes |
that |
T383 |
865-869 |
NN |
denotes |
Sox6 |
T384 |
870-874 |
VB |
denotes |
acts |
T385 |
875-877 |
IN |
denotes |
as |
T386 |
878-879 |
DT |
denotes |
a |
T387 |
880-889 |
NN |
denotes |
repressor |
T388 |
890-892 |
IN |
denotes |
by |
T389 |
893-901 |
RB |
denotes |
directly |
T390 |
902-909 |
VB |
denotes |
binding |
T391 |
910-912 |
TO |
denotes |
to |
T392 |
913-916 |
DT |
denotes |
the |
T393 |
917-919 |
JJ |
denotes |
ɛy |
T394 |
920-928 |
NN |
denotes |
promoter |
T395 |
930-933 |
DT |
denotes |
The |
T396 |
934-940 |
JJ |
denotes |
normal |
T397 |
941-951 |
NN |
denotes |
expression |
T398 |
952-954 |
IN |
denotes |
of |
T399 |
955-959 |
NN |
denotes |
Sox6 |
T400 |
960-962 |
IN |
denotes |
in |
T401 |
963-972 |
JJ |
denotes |
wild-type |
T402 |
973-978 |
JJ |
denotes |
fetal |
T403 |
979-984 |
NN |
denotes |
liver |
T404 |
985-988 |
CC |
denotes |
and |
T405 |
989-992 |
DT |
denotes |
the |
T406 |
993-1000 |
JJ |
denotes |
ectopic |
T407 |
1001-1011 |
NN |
denotes |
expression |
T408 |
1012-1014 |
IN |
denotes |
of |
T409 |
1015-1017 |
NN |
denotes |
ɛy |
T410 |
1018-1020 |
IN |
denotes |
in |
T411 |
1021-1026 |
NN |
denotes |
p100H |
T412 |
1027-1037 |
JJ |
denotes |
homozygous |
T413 |
1038-1043 |
JJ |
denotes |
fetal |
T414 |
1044-1049 |
NN |
denotes |
liver |
T415 |
1050-1061 |
VB |
denotes |
demonstrate |
T416 |
1062-1066 |
IN |
denotes |
that |
T417 |
1067-1071 |
NN |
denotes |
Sox6 |
T418 |
1072-1081 |
NN |
denotes |
functions |
T419 |
1082-1084 |
IN |
denotes |
in |
T420 |
1085-1095 |
JJ |
denotes |
definitive |
T421 |
1096-1110 |
NN |
denotes |
erythropoiesis |
T422 |
1112-1115 |
DT |
denotes |
The |
T423 |
1116-1123 |
JJ |
denotes |
present |
T424 |
1124-1129 |
NN |
denotes |
study |
T425 |
1130-1135 |
VB |
denotes |
shows |
T426 |
1136-1140 |
IN |
denotes |
that |
T427 |
1141-1145 |
NN |
denotes |
Sox6 |
T428 |
1146-1148 |
VB |
denotes |
is |
T429 |
1149-1157 |
VB |
denotes |
required |
T430 |
1158-1161 |
IN |
denotes |
for |
T431 |
1162-1171 |
NN |
denotes |
silencing |
T432 |
1172-1174 |
IN |
denotes |
of |
T433 |
1175-1177 |
JJ |
denotes |
ɛy |
T434 |
1178-1184 |
NN |
denotes |
globin |
T435 |
1185-1187 |
IN |
denotes |
in |
T436 |
1188-1198 |
JJ |
denotes |
definitive |
T437 |
1199-1213 |
NN |
denotes |
erythropoiesis |
T438 |
1214-1217 |
CC |
denotes |
and |
T439 |
1218-1226 |
VB |
denotes |
suggests |
T440 |
1227-1228 |
DT |
denotes |
a |
T441 |
1229-1233 |
NN |
denotes |
role |
T442 |
1234-1237 |
IN |
denotes |
for |
T443 |
1238-1242 |
NN |
denotes |
Sox6 |
T444 |
1243-1245 |
IN |
denotes |
in |
T445 |
1246-1255 |
JJ |
denotes |
erythroid |
T446 |
1256-1260 |
NN |
denotes |
cell |
T447 |
1261-1271 |
NN |
denotes |
maturation |
T448 |
1273-1277 |
RB |
denotes |
Thus |
T449 |
1277-1278 |
-COMMA- |
denotes |
, |
T450 |
1279-1283 |
NN |
denotes |
Sox6 |
T451 |
1284-1294 |
NN |
denotes |
regulation |
T452 |
1295-1297 |
IN |
denotes |
of |
T453 |
1298-1300 |
JJ |
denotes |
ɛy |
T454 |
1301-1307 |
NN |
denotes |
globin |
T455 |
1308-1313 |
MD |
denotes |
might |
T456 |
1314-1321 |
VB |
denotes |
provide |
T457 |
1322-1323 |
DT |
denotes |
a |
T458 |
1324-1329 |
JJ |
denotes |
novel |
T459 |
1330-1343 |
JJ |
denotes |
therapeutical |
T460 |
1344-1350 |
NN |
denotes |
target |
T461 |
1351-1353 |
IN |
denotes |
in |
T462 |
1354-1357 |
DT |
denotes |
the |
T463 |
1358-1367 |
NN |
denotes |
treatment |
T464 |
1368-1370 |
IN |
denotes |
of |
T465 |
1371-1389 |
NN |
denotes |
hemoglobinopathies |
T466 |
1390-1394 |
JJ |
denotes |
such |
T467 |
1395-1397 |
IN |
denotes |
as |
T468 |
1398-1404 |
JJ |
denotes |
sickle |
T469 |
1405-1409 |
NN |
denotes |
cell |
T470 |
1410-1416 |
NN |
denotes |
anemia |
T471 |
1417-1420 |
CC |
denotes |
and |
T472 |
1421-1432 |
NN |
denotes |
thalassemia |
T1696 |
2855-2858 |
NN |
denotes |
Sry |
T1697 |
2859-2863 |
NN |
denotes |
type |
T1698 |
2864-2867 |
NN |
denotes |
HMG |
T1699 |
2868-2871 |
NN |
denotes |
box |
T1700 |
2872-2873 |
-LRB- |
denotes |
( |
T1701 |
2873-2877 |
NN |
denotes |
Sox6 |
T1702 |
2877-2878 |
-RRB- |
denotes |
) |
T1703 |
2879-2881 |
VB |
denotes |
is |
T1704 |
2882-2883 |
DT |
denotes |
a |
T1705 |
2884-2890 |
NN |
denotes |
member |
T1706 |
2891-2893 |
IN |
denotes |
of |
T1707 |
2894-2897 |
DT |
denotes |
the |
T1708 |
2898-2901 |
NN |
denotes |
Sox |
T1709 |
2902-2915 |
NN |
denotes |
transcription |
T1710 |
2916-2922 |
NN |
denotes |
factor |
T1711 |
2923-2929 |
NN |
denotes |
family |
T1712 |
2930-2943 |
VB |
denotes |
characterized |
T1713 |
2944-2946 |
IN |
denotes |
by |
T1714 |
2947-2950 |
DT |
denotes |
the |
T1715 |
2951-2960 |
VB |
denotes |
conserved |
T1716 |
2961-2965 |
JJ |
denotes |
high |
T1717 |
2966-2974 |
NN |
denotes |
mobility |
T1718 |
2975-2980 |
NN |
denotes |
group |
T1719 |
2981-2982 |
-LRB- |
denotes |
( |
T1720 |
2982-2985 |
NN |
denotes |
HMG |
T1721 |
2985-2986 |
-RRB- |
denotes |
) |
T1722 |
2987-2993 |
NN |
denotes |
domain |
T1723 |
2993-2994 |
-COMMA- |
denotes |
, |
T1724 |
2995-3005 |
VB |
denotes |
consisting |
T1725 |
3006-3008 |
IN |
denotes |
of |
T1726 |
3009-3011 |
CD |
denotes |
79 |
T1727 |
3012-3017 |
NN |
denotes |
amino |
T1728 |
3018-3023 |
NN |
denotes |
acids |
T1729 |
3024-3032 |
VB |
denotes |
involved |
T1730 |
3033-3035 |
IN |
denotes |
in |
T1731 |
3036-3039 |
NN |
denotes |
DNA |
T1732 |
3040-3051 |
NN |
denotes |
recognition |
T1733 |
3052-3055 |
CC |
denotes |
and |
T1734 |
3056-3063 |
NN |
denotes |
binding |
T1735 |
3064-3065 |
-LRB- |
denotes |
[ |
T1736 |
3065-3066 |
CD |
denotes |
1 |
T1737 |
3066-3067 |
-RRB- |
denotes |
] |
T1738 |
3069-3072 |
NN |
denotes |
Sox |
T1739 |
3073-3086 |
NN |
denotes |
transcription |
T1740 |
3087-3094 |
NN |
denotes |
factors |
T1741 |
3095-3099 |
VB |
denotes |
bind |
T1742 |
3100-3102 |
TO |
denotes |
to |
T1743 |
3103-3106 |
DT |
denotes |
the |
T1744 |
3107-3112 |
JJ |
denotes |
minor |
T1745 |
3113-3119 |
NN |
denotes |
groove |
T1746 |
3120-3122 |
IN |
denotes |
of |
T1747 |
3123-3126 |
NN |
denotes |
DNA |
T1748 |
3127-3130 |
CC |
denotes |
and |
T1749 |
3131-3136 |
VB |
denotes |
cause |
T1750 |
3137-3138 |
DT |
denotes |
a |
T1751 |
3139-3146 |
JJ |
denotes |
70°–85° |
T1752 |
3147-3151 |
NN |
denotes |
bend |
T1753 |
3152-3154 |
IN |
denotes |
of |
T1754 |
3155-3158 |
DT |
denotes |
the |
T1755 |
3159-3162 |
NN |
denotes |
DNA |
T1756 |
3163-3167 |
WDT |
denotes |
that |
T1757 |
3168-3173 |
VB |
denotes |
leads |
T1758 |
3174-3176 |
TO |
denotes |
to |
T1759 |
3177-3182 |
JJ |
denotes |
local |
T1760 |
3183-3197 |
JJ |
denotes |
conformational |
T1761 |
3198-3205 |
NN |
denotes |
changes |
T1762 |
3206-3207 |
-LRB- |
denotes |
[ |
T1763 |
3207-3210 |
CD |
denotes |
2,3 |
T1764 |
3210-3211 |
-RRB- |
denotes |
] |
T1765 |
3211-3212 |
-COMMA- |
denotes |
, |
T1766 |
3213-3218 |
IN |
denotes |
while |
T1767 |
3219-3223 |
JJ |
denotes |
most |
T1768 |
3224-3229 |
JJ |
denotes |
other |
T1769 |
3230-3243 |
NN |
denotes |
transcription |
T1770 |
3244-3251 |
NN |
denotes |
factors |
T1771 |
3252-3258 |
VB |
denotes |
target |
T1772 |
3259-3262 |
DT |
denotes |
the |
T1773 |
3263-3268 |
JJ |
denotes |
major |
T1774 |
3269-3275 |
NN |
denotes |
groove |
T1775 |
3276-3278 |
IN |
denotes |
of |
T1776 |
3279-3282 |
NN |
denotes |
DNA |
T1777 |
3283-3284 |
-LRB- |
denotes |
[ |
T1778 |
3284-3285 |
CD |
denotes |
4 |
T1779 |
3285-3286 |
-RRB- |
denotes |
] |
T1780 |
3288-3297 |
RB |
denotes |
Therefore |
T1781 |
3297-3298 |
-COMMA- |
denotes |
, |
T1782 |
3299-3302 |
NN |
denotes |
Sox |
T1783 |
3303-3311 |
NN |
denotes |
proteins |
T1784 |
3312-3315 |
MD |
denotes |
may |
T1785 |
3316-3323 |
VB |
denotes |
perform |
T1786 |
3324-3328 |
NN |
denotes |
part |
T1787 |
3329-3331 |
IN |
denotes |
of |
T1788 |
3332-3337 |
PRP-DOLLAR- |
denotes |
their |
T1789 |
3338-3346 |
NN |
denotes |
function |
T1790 |
3347-3349 |
IN |
denotes |
as |
T1791 |
3350-3363 |
JJ |
denotes |
architectural |
T1792 |
3364-3372 |
NN |
denotes |
proteins |
T1793 |
3373-3375 |
IN |
denotes |
by |
T1794 |
3376-3386 |
VB |
denotes |
organizing |
T1795 |
3387-3392 |
JJ |
denotes |
local |
T1796 |
3393-3402 |
NN |
denotes |
chromatin |
T1797 |
3403-3412 |
NN |
denotes |
structure |
T1798 |
3413-3416 |
CC |
denotes |
and |
T1799 |
3417-3427 |
VB |
denotes |
assembling |
T1800 |
3428-3433 |
JJ |
denotes |
other |
T1801 |
3434-3443 |
JJ |
denotes |
DNA-bound |
T1802 |
3444-3457 |
NN |
denotes |
transcription |
T1803 |
3458-3465 |
NN |
denotes |
factors |
T1804 |
3466-3470 |
IN |
denotes |
into |
T1805 |
3471-3483 |
RB |
denotes |
biologically |
T1806 |
3484-3490 |
JJ |
denotes |
active |
T1807 |
3490-3491 |
-COMMA- |
denotes |
, |
T1808 |
3492-3502 |
RB |
denotes |
sterically |
T1809 |
3503-3510 |
VB |
denotes |
defined |
T1810 |
3511-3523 |
NN |
denotes |
multiprotein |
T1811 |
3524-3533 |
NN |
denotes |
complexes |
T1812 |
3535-3539 |
NN |
denotes |
Sox6 |
T1813 |
3540-3543 |
VB |
denotes |
has |
T1814 |
3544-3548 |
VB |
denotes |
been |
T1815 |
3549-3557 |
VB |
denotes |
reported |
T1816 |
3558-3560 |
TO |
denotes |
to |
T1817 |
3561-3563 |
VB |
denotes |
be |
T1818 |
3564-3568 |
JJ |
denotes |
able |
T1819 |
3569-3571 |
TO |
denotes |
to |
T1820 |
3572-3575 |
VB |
denotes |
act |
T1821 |
3576-3578 |
IN |
denotes |
as |
T1822 |
3579-3585 |
CC |
denotes |
either |
T1823 |
3586-3588 |
DT |
denotes |
an |
T1824 |
3589-3598 |
NN |
denotes |
activator |
T1825 |
3599-3601 |
CC |
denotes |
or |
T1826 |
3602-3603 |
DT |
denotes |
a |
T1827 |
3604-3613 |
NN |
denotes |
repressor |
T1828 |
3613-3614 |
-COMMA- |
denotes |
, |
T1829 |
3615-3624 |
VB |
denotes |
depending |
T1830 |
3625-3627 |
IN |
denotes |
on |
T1831 |
3628-3631 |
PRP-DOLLAR- |
denotes |
its |
T1832 |
3632-3643 |
NN |
denotes |
interactors |
T1833 |
3644-3647 |
CC |
denotes |
and |
T1834 |
3648-3651 |
PRP-DOLLAR- |
denotes |
its |
T1835 |
3652-3658 |
NN |
denotes |
target |
T1836 |
3659-3667 |
NN |
denotes |
promoter |
T1837 |
3668-3675 |
NN |
denotes |
context |
T1838 |
3676-3677 |
-LRB- |
denotes |
[ |
T1839 |
3677-3680 |
CD |
denotes |
5,6 |
T1840 |
3680-3681 |
-RRB- |
denotes |
] |
T1841 |
3683-3695 |
RB |
denotes |
Intriguingly |
T1842 |
3695-3696 |
-COMMA- |
denotes |
, |
T1843 |
3697-3701 |
NN |
denotes |
Sox6 |
T1844 |
3702-3705 |
VB |
denotes |
has |
T1845 |
3706-3710 |
RB |
denotes |
also |
T1846 |
3711-3715 |
VB |
denotes |
been |
T1847 |
3716-3721 |
VB |
denotes |
shown |
T1848 |
3722-3724 |
TO |
denotes |
to |
T1849 |
3725-3728 |
VB |
denotes |
act |
T1850 |
3729-3731 |
IN |
denotes |
as |
T1851 |
3732-3733 |
DT |
denotes |
a |
T1852 |
3734-3741 |
JJ |
denotes |
general |
T1853 |
3742-3750 |
NN |
denotes |
splicing |
T1854 |
3751-3757 |
NN |
denotes |
factor |
T1855 |
3758-3762 |
WDT |
denotes |
that |
T1856 |
3763-3775 |
VB |
denotes |
participates |
T1857 |
3776-3778 |
IN |
denotes |
in |
T1858 |
3779-3787 |
JJ |
denotes |
pre-mRNA |
T1859 |
3788-3796 |
NN |
denotes |
splicing |
T1860 |
3797-3798 |
-LRB- |
denotes |
[ |
T1861 |
3798-3799 |
CD |
denotes |
7 |
T1862 |
3799-3800 |
-RRB- |
denotes |
] |
T1863 |
3802-3811 |
NN |
denotes |
Depletion |
T1864 |
3812-3814 |
IN |
denotes |
of |
T1865 |
3815-3819 |
NN |
denotes |
Sox6 |
T1866 |
3820-3822 |
IN |
denotes |
in |
T1867 |
3823-3827 |
NN |
denotes |
HeLa |
T1868 |
3828-3832 |
NN |
denotes |
cell |
T1869 |
3833-3841 |
NN |
denotes |
extracts |
T1870 |
3842-3849 |
VB |
denotes |
blocked |
T1871 |
3850-3858 |
NN |
denotes |
splicing |
T1872 |
3859-3861 |
IN |
denotes |
of |
T1873 |
3862-3870 |
JJ |
denotes |
multiple |
T1874 |
3871-3881 |
NN |
denotes |
substrates |
T1875 |
3881-3882 |
-COMMA- |
denotes |
, |
T1876 |
3883-3886 |
CC |
denotes |
and |
T1877 |
3887-3897 |
NN |
denotes |
expression |
T1878 |
3898-3900 |
IN |
denotes |
of |
T1879 |
3901-3904 |
DT |
denotes |
the |
T1880 |
3905-3908 |
NN |
denotes |
HMG |
T1881 |
3909-3915 |
NN |
denotes |
domain |
T1882 |
3916-3918 |
IN |
denotes |
of |
T1883 |
3919-3925 |
DT |
denotes |
either |
T1884 |
3926-3930 |
NN |
denotes |
Sox6 |
T1885 |
3930-3931 |
-COMMA- |
denotes |
, |
T1886 |
3932-3936 |
NN |
denotes |
Sox9 |
T1887 |
3936-3937 |
-COMMA- |
denotes |
, |
T1888 |
3938-3940 |
CC |
denotes |
or |
T1889 |
3941-3944 |
NN |
denotes |
Sry |
T1890 |
3945-3947 |
IN |
denotes |
in |
T1891 |
3948-3951 |
DT |
denotes |
the |
T1892 |
3952-3960 |
NN |
denotes |
extracts |
T1893 |
3961-3969 |
VB |
denotes |
restored |
T1894 |
3970-3978 |
NN |
denotes |
splicing |
T1895 |
3978-3979 |
-COMMA- |
denotes |
, |
T1896 |
3980-3990 |
VB |
denotes |
indicating |
T1897 |
3991-4001 |
JJ |
denotes |
functional |
T1898 |
4002-4009 |
NN |
denotes |
overlap |
T1899 |
4010-4012 |
IN |
denotes |
of |
T1900 |
4013-4018 |
DT |
denotes |
these |
T1901 |
4019-4027 |
NN |
denotes |
proteins |
T1902 |
4028-4029 |
-LRB- |
denotes |
[ |
T1903 |
4029-4030 |
CD |
denotes |
7 |
T1904 |
4030-4031 |
-RRB- |
denotes |
] |
T1905 |
4033-4043 |
RB |
denotes |
Regardless |
T1906 |
4044-4046 |
IN |
denotes |
of |
T1907 |
4047-4050 |
WRB |
denotes |
how |
T1908 |
4051-4055 |
NN |
denotes |
Sox6 |
T1909 |
4056-4065 |
NN |
denotes |
functions |
T1910 |
4066-4068 |
IN |
denotes |
in |
T1911 |
4069-4079 |
VB |
denotes |
regulating |
T1912 |
4080-4084 |
NN |
denotes |
gene |
T1913 |
4085-4095 |
NN |
denotes |
expression |
T1914 |
4095-4096 |
-COMMA- |
denotes |
, |
T1915 |
4097-4105 |
JJ |
denotes |
previous |
T1916 |
4106-4113 |
NN |
denotes |
studies |
T1917 |
4114-4118 |
VB |
denotes |
have |
T1918 |
4119-4131 |
VB |
denotes |
demonstrated |
T1919 |
4132-4136 |
IN |
denotes |
that |
T1920 |
4137-4141 |
NN |
denotes |
Sox6 |
T1921 |
4142-4144 |
VB |
denotes |
is |
T1922 |
4145-4147 |
DT |
denotes |
an |
T1923 |
4148-4157 |
JJ |
denotes |
important |
T1924 |
4158-4168 |
JJ |
denotes |
regulatory |
T1925 |
4169-4177 |
NN |
denotes |
molecule |
T1926 |
4178-4182 |
WDT |
denotes |
that |
T1927 |
4183-4188 |
VB |
denotes |
plays |
T1928 |
4189-4190 |
DT |
denotes |
a |
T1929 |
4191-4195 |
NN |
denotes |
role |
T1930 |
4196-4198 |
IN |
denotes |
in |
T1931 |
4199-4202 |
DT |
denotes |
the |
T1932 |
4203-4214 |
NN |
denotes |
development |
T1933 |
4215-4217 |
IN |
denotes |
of |
T1934 |
4218-4221 |
DT |
denotes |
the |
T1935 |
4222-4229 |
JJ |
denotes |
central |
T1936 |
4230-4237 |
JJ |
denotes |
nervous |
T1937 |
4238-4244 |
NN |
denotes |
system |
T1938 |
4245-4246 |
-LRB- |
denotes |
[ |
T1939 |
4246-4250 |
CD |
denotes |
8–11 |
T1940 |
4250-4251 |
-RRB- |
denotes |
] |
T1941 |
4251-4252 |
-COMMA- |
denotes |
, |
T1942 |
4253-4262 |
NN |
denotes |
cartilage |
T1943 |
4263-4264 |
-LRB- |
denotes |
[ |
T1944 |
4264-4271 |
CD |
denotes |
6,12,13 |
T1945 |
4271-4272 |
-RRB- |
denotes |
] |
T1946 |
4272-4273 |
-COMMA- |
denotes |
, |
T1947 |
4274-4277 |
CC |
denotes |
and |
T1948 |
4278-4284 |
NN |
denotes |
muscle |
T1949 |
4285-4286 |
-LRB- |
denotes |
[ |
T1950 |
4286-4291 |
CD |
denotes |
14,15 |
T1951 |
4291-4292 |
-RRB- |
denotes |
] |
T1952 |
4294-4295 |
DT |
denotes |
A |
T1953 |
4296-4305 |
JJ |
denotes |
Sox6-null |
T1954 |
4306-4312 |
JJ |
denotes |
mutant |
T1955 |
4313-4318 |
NN |
denotes |
mouse |
T1956 |
4319-4320 |
-LRB- |
denotes |
( |
T1957 |
4320-4325 |
NN |
denotes |
p100H |
T1958 |
4325-4326 |
-RRB- |
denotes |
) |
T1959 |
4327-4330 |
VB |
denotes |
has |
T1960 |
4331-4341 |
RB |
denotes |
previously |
T1961 |
4342-4346 |
VB |
denotes |
been |
T1962 |
4347-4357 |
VB |
denotes |
identified |
T1963 |
4358-4360 |
IN |
denotes |
in |
T1964 |
4361-4364 |
PRP-DOLLAR- |
denotes |
our |
T1965 |
4365-4375 |
NN |
denotes |
laboratory |
T1966 |
4376-4377 |
-LRB- |
denotes |
[ |
T1967 |
4377-4379 |
CD |
denotes |
14 |
T1968 |
4379-4380 |
-RRB- |
denotes |
] |
T1969 |
4382-4386 |
NN |
denotes |
Mice |
T1970 |
4387-4397 |
JJ |
denotes |
homozygous |
T1971 |
4398-4401 |
IN |
denotes |
for |
T1972 |
4402-4407 |
NN |
denotes |
p100H |
T1973 |
4408-4412 |
VB |
denotes |
show |
T1974 |
4413-4420 |
VB |
denotes |
delayed |
T1975 |
4421-4427 |
NN |
denotes |
growth |
T1976 |
4427-4428 |
-COMMA- |
denotes |
, |
T1977 |
4429-4436 |
VB |
denotes |
develop |
T1978 |
4437-4445 |
NN |
denotes |
myopathy |
T1979 |
4446-4449 |
CC |
denotes |
and |
T1980 |
4450-4468 |
JJ |
denotes |
arterioventricular |
T1981 |
4469-4474 |
NN |
denotes |
heart |
T1982 |
4475-4480 |
NN |
denotes |
block |
T1983 |
4480-4481 |
-COMMA- |
denotes |
, |
T1984 |
4482-4485 |
CC |
denotes |
and |
T1985 |
4486-4489 |
VB |
denotes |
die |
T1986 |
4490-4496 |
IN |
denotes |
within |
T1987 |
4497-4498 |
CD |
denotes |
2 |
T1988 |
4499-4501 |
NN |
denotes |
wk |
T1989 |
4502-4507 |
IN |
denotes |
after |
T1990 |
4508-4513 |
NN |
denotes |
birth |
T1991 |
4514-4515 |
-LRB- |
denotes |
[ |
T1992 |
4515-4517 |
CD |
denotes |
14 |
T1993 |
4517-4518 |
-RRB- |
denotes |
] |
T1994 |
4520-4523 |
DT |
denotes |
The |
T1995 |
4524-4529 |
NN |
denotes |
p100H |
T1996 |
4530-4536 |
JJ |
denotes |
mutant |
T1997 |
4537-4543 |
NN |
denotes |
allele |
T1998 |
4544-4546 |
VB |
denotes |
is |
T1999 |
4547-4557 |
VB |
denotes |
associated |
T2000 |
4558-4562 |
IN |
denotes |
with |
T2001 |
4563-4564 |
DT |
denotes |
a |
T2002 |
4565-4575 |
NN |
denotes |
Chromosome |
T2003 |
4576-4577 |
CD |
denotes |
7 |
T2004 |
4578-4587 |
NN |
denotes |
inversion |
T2005 |
4588-4592 |
WDT |
denotes |
that |
T2006 |
4593-4601 |
VB |
denotes |
disrupts |
T2007 |
4602-4606 |
CC |
denotes |
both |
T2008 |
4607-4610 |
DT |
denotes |
the |
T2009 |
4611-4612 |
NN |
denotes |
p |
T2010 |
4613-4617 |
NN |
denotes |
gene |
T2011 |
4618-4621 |
CC |
denotes |
and |
T2012 |
4622-4625 |
DT |
denotes |
the |
T2013 |
4626-4630 |
NN |
denotes |
Sox6 |
T2014 |
4631-4635 |
NN |
denotes |
gene |
T2015 |
4636-4637 |
-LRB- |
denotes |
( |
T2016 |
4637-4640 |
CC |
denotes |
and |
T2017 |
4641-4643 |
DT |
denotes |
no |
T2018 |
4644-4649 |
JJ |
denotes |
other |
T2019 |
4650-4654 |
NN |
denotes |
gene |
T2020 |
4655-4661 |
IN |
denotes |
within |
T2021 |
4662-4668 |
CD |
denotes |
50,000 |
T2022 |
4669-4680 |
NN |
denotes |
nucleotides |
T2023 |
4681-4683 |
IN |
denotes |
of |
T2024 |
4684-4687 |
DT |
denotes |
the |
T2025 |
4688-4699 |
JJ |
denotes |
chromosomal |
T2026 |
4700-4711 |
NN |
denotes |
breakpoints |
T2027 |
4711-4712 |
-RRB- |
denotes |
) |
T2028 |
4713-4714 |
-LRB- |
denotes |
[ |
T2029 |
4714-4716 |
CD |
denotes |
14 |
T2030 |
4716-4717 |
-RRB- |
denotes |
] |
T2031 |
4719-4726 |
IN |
denotes |
Because |
T2032 |
4727-4730 |
DT |
denotes |
the |
T2033 |
4731-4732 |
NN |
denotes |
p |
T2034 |
4733-4737 |
NN |
denotes |
gene |
T2035 |
4738-4747 |
VB |
denotes |
functions |
T2036 |
4748-4754 |
RB |
denotes |
solely |
T2037 |
4755-4757 |
IN |
denotes |
in |
T2038 |
4758-4770 |
NN |
denotes |
pigmentation |
T2039 |
4771-4772 |
-LRB- |
denotes |
[ |
T2040 |
4772-4774 |
CD |
denotes |
16 |
T2041 |
4774-4775 |
-RRB- |
denotes |
] |
T2042 |
4775-4776 |
-COMMA- |
denotes |
, |
T2043 |
4777-4780 |
DT |
denotes |
the |
T2044 |
4781-4785 |
NN |
denotes |
Sox6 |
T2045 |
4786-4799 |
NN |
denotes |
transcription |
T2046 |
4800-4806 |
NN |
denotes |
factor |
T2047 |
4807-4809 |
VB |
denotes |
is |
T2048 |
4810-4820 |
VB |
denotes |
implicated |
T2049 |
4821-4823 |
IN |
denotes |
in |
T2050 |
4824-4827 |
DT |
denotes |
all |
T2051 |
4828-4833 |
JJ |
denotes |
other |
T2052 |
4834-4844 |
NN |
denotes |
phenotypes |
T2053 |
4846-4851 |
IN |
denotes |
Among |
T2054 |
4852-4855 |
DT |
denotes |
the |
T2055 |
4856-4859 |
NN |
denotes |
HMG |
T2056 |
4860-4863 |
NN |
denotes |
box |
T2057 |
4864-4872 |
NN |
denotes |
proteins |
T2058 |
4873-4882 |
RB |
denotes |
distantly |
T2059 |
4883-4890 |
VB |
denotes |
related |
T2060 |
4891-4893 |
TO |
denotes |
to |
T2061 |
4894-4897 |
NN |
denotes |
Sry |
T2062 |
4898-4899 |
-LRB- |
denotes |
( |
T2063 |
4899-4902 |
DT |
denotes |
the |
T2064 |
4903-4908 |
JJ |
denotes |
first |
T2065 |
4909-4915 |
NN |
denotes |
member |
T2066 |
4916-4926 |
VB |
denotes |
identified |
T2067 |
4927-4929 |
IN |
denotes |
of |
T2068 |
4930-4933 |
DT |
denotes |
the |
T2069 |
4934-4937 |
NN |
denotes |
Sox |
T2070 |
4938-4951 |
NN |
denotes |
transcription |
T2071 |
4952-4958 |
NN |
denotes |
factor |
T2072 |
4959-4965 |
NN |
denotes |
family |
T2073 |
4965-4966 |
-RRB- |
denotes |
) |
T2074 |
4967-4971 |
WDT |
denotes |
that |
T2075 |
4972-4981 |
RB |
denotes |
similarly |
T2076 |
4982-4986 |
VB |
denotes |
bind |
T2077 |
4987-4989 |
TO |
denotes |
to |
T2078 |
4990-4993 |
DT |
denotes |
the |
T2079 |
4994-4999 |
JJ |
denotes |
minor |
T2080 |
5000-5006 |
NN |
denotes |
groove |
T2081 |
5007-5010 |
CC |
denotes |
and |
T2082 |
5011-5015 |
NN |
denotes |
bend |
T2083 |
5016-5019 |
NN |
denotes |
DNA |
T2084 |
5019-5020 |
-COMMA- |
denotes |
, |
T2085 |
5021-5024 |
CC |
denotes |
but |
T2086 |
5025-5032 |
IN |
denotes |
without |
T2087 |
5033-5041 |
NN |
denotes |
sequence |
T2088 |
5042-5053 |
NN |
denotes |
specificity |
T2089 |
5053-5054 |
-COMMA- |
denotes |
, |
T2090 |
5055-5058 |
VB |
denotes |
are |
T2091 |
5059-5062 |
DT |
denotes |
the |
T2092 |
5063-5075 |
RB |
denotes |
ubiquitously |
T2093 |
5076-5085 |
VB |
denotes |
expressed |
T2094 |
5086-5090 |
NN |
denotes |
HMG1 |
T2095 |
5091-5094 |
CC |
denotes |
and |
T2096 |
5095-5099 |
NN |
denotes |
HMG2 |
T2097 |
5100-5108 |
NN |
denotes |
proteins |
T2098 |
5109-5110 |
-LRB- |
denotes |
[ |
T2099 |
5110-5112 |
CD |
denotes |
17 |
T2100 |
5112-5113 |
-RRB- |
denotes |
] |
T2101 |
5115-5125 |
NN |
denotes |
Modulation |
T2102 |
5126-5128 |
IN |
denotes |
of |
T2103 |
5129-5132 |
NN |
denotes |
DNA |
T2104 |
5133-5142 |
NN |
denotes |
structure |
T2105 |
5143-5145 |
IN |
denotes |
by |
T2106 |
5146-5151 |
DT |
denotes |
these |
T2107 |
5152-5155 |
CC |
denotes |
and |
T2108 |
5156-5161 |
JJ |
denotes |
other |
T2109 |
5162-5165 |
NN |
denotes |
HMG |
T2110 |
5166-5174 |
NN |
denotes |
proteins |
T2111 |
5175-5178 |
MD |
denotes |
can |
T2112 |
5179-5186 |
VB |
denotes |
mediate |
T2113 |
5187-5197 |
JJ |
denotes |
long-range |
T2114 |
5198-5206 |
NN |
denotes |
enhancer |
T2115 |
5207-5215 |
NN |
denotes |
function |
T2116 |
5216-5218 |
IN |
denotes |
on |
T2117 |
5219-5223 |
CC |
denotes |
both |
T2118 |
5224-5227 |
NN |
denotes |
DNA |
T2119 |
5228-5231 |
CC |
denotes |
and |
T2120 |
5232-5251 |
JJ |
denotes |
chromatin-assembled |
T2121 |
5252-5257 |
NN |
denotes |
genes |
T2122 |
5258-5260 |
IN |
denotes |
by |
T2123 |
5261-5269 |
VB |
denotes |
bringing |
T2124 |
5270-5278 |
RB |
denotes |
together |
T2125 |
5279-5286 |
JJ |
denotes |
distant |
T2126 |
5287-5294 |
NN |
denotes |
regions |
T2127 |
5295-5297 |
IN |
denotes |
of |
T2128 |
5298-5301 |
NN |
denotes |
DNA |
T2129 |
5302-5305 |
CC |
denotes |
and |
T2130 |
5306-5316 |
VB |
denotes |
associated |
T2131 |
5317-5324 |
NN |
denotes |
factors |
T2132 |
5326-5338 |
RB |
denotes |
Specifically |
T2133 |
5338-5339 |
-COMMA- |
denotes |
, |
T2134 |
5340-5343 |
NN |
denotes |
HMG |
T2135 |
5344-5352 |
NN |
denotes |
proteins |
T2136 |
5353-5357 |
VB |
denotes |
have |
T2137 |
5358-5362 |
VB |
denotes |
been |
T2138 |
5363-5368 |
VB |
denotes |
shown |
T2139 |
5369-5371 |
TO |
denotes |
to |
T2140 |
5372-5380 |
VB |
denotes |
modulate |
T2141 |
5381-5389 |
JJ |
denotes |
β-globin |
T2142 |
5390-5395 |
NN |
denotes |
genes |
T2143 |
5396-5397 |
-LRB- |
denotes |
[ |
T2144 |
5397-5402 |
CD |
denotes |
18–21 |
T2145 |
5402-5403 |
-RRB- |
denotes |
] |
T2146 |
5405-5408 |
DT |
denotes |
The |
T2147 |
5409-5414 |
NN |
denotes |
mouse |
T2148 |
5415-5423 |
NN |
denotes |
β-globin |
T2149 |
5424-5429 |
NN |
denotes |
genes |
T2150 |
5430-5431 |
-LRB- |
denotes |
{ |
T2151 |
5431-5433 |
NN |
denotes |
ɛy |
T2152 |
5433-5434 |
-COMMA- |
denotes |
, |
T2153 |
5435-5438 |
NN |
denotes |
βh1 |
T2154 |
5438-5439 |
-COMMA- |
denotes |
, |
T2155 |
5440-5447 |
JJ |
denotes |
β-major |
T2156 |
5447-5448 |
-COMMA- |
denotes |
, |
T2157 |
5449-5452 |
CC |
denotes |
and |
T2158 |
5453-5460 |
JJ |
denotes |
β-minor |
T2159 |
5460-5461 |
-RRB- |
denotes |
} |
T2160 |
5462-5465 |
VB |
denotes |
are |
T2161 |
5466-5475 |
VB |
denotes |
clustered |
T2162 |
5476-5478 |
IN |
denotes |
on |
T2163 |
5479-5489 |
NN |
denotes |
Chromosome |
T2164 |
5490-5491 |
CD |
denotes |
7 |
T2165 |
5492-5495 |
CC |
denotes |
and |
T2166 |
5496-5500 |
PRP |
denotes |
they |
T2167 |
5501-5504 |
VB |
denotes |
are |
T2168 |
5505-5511 |
RB |
denotes |
highly |
T2169 |
5512-5522 |
JJ |
denotes |
homologous |
T2170 |
5523-5525 |
TO |
denotes |
to |
T2171 |
5526-5531 |
PRP-DOLLAR- |
denotes |
their |
T2172 |
5532-5537 |
JJ |
denotes |
human |
T2173 |
5538-5550 |
NN |
denotes |
counterparts |
T2174 |
5551-5553 |
IN |
denotes |
in |
T2175 |
5554-5568 |
JJ |
denotes |
organizational |
T2176 |
5569-5578 |
NN |
denotes |
structure |
T2177 |
5579-5582 |
CC |
denotes |
and |
T2178 |
5583-5591 |
NN |
denotes |
function |
T2179 |
5592-5593 |
-LRB- |
denotes |
[ |
T2180 |
5593-5595 |
CD |
denotes |
22 |
T2181 |
5595-5596 |
-RRB- |
denotes |
] |
T2182 |
5598-5608 |
JJ |
denotes |
High-level |
T2183 |
5609-5619 |
NN |
denotes |
expression |
T2184 |
5620-5622 |
IN |
denotes |
of |
T2185 |
5623-5628 |
DT |
denotes |
these |
T2186 |
5629-5634 |
NN |
denotes |
genes |
T2187 |
5635-5643 |
VB |
denotes |
requires |
T2188 |
5644-5645 |
DT |
denotes |
a |
T2189 |
5646-5656 |
JJ |
denotes |
regulatory |
T2190 |
5657-5664 |
NN |
denotes |
element |
T2191 |
5664-5665 |
-COMMA- |
denotes |
, |
T2192 |
5666-5669 |
DT |
denotes |
the |
T2193 |
5670-5675 |
NN |
denotes |
locus |
T2194 |
5676-5683 |
NN |
denotes |
control |
T2195 |
5684-5690 |
NN |
denotes |
region |
T2196 |
5691-5695 |
WDT |
denotes |
that |
T2197 |
5696-5698 |
VB |
denotes |
is |
T2198 |
5699-5712 |
VB |
denotes |
characterized |
T2199 |
5713-5715 |
IN |
denotes |
by |
T2200 |
5716-5717 |
DT |
denotes |
a |
T2201 |
5718-5721 |
NN |
denotes |
set |
T2202 |
5722-5724 |
IN |
denotes |
of |
T2203 |
5725-5733 |
NN |
denotes |
nuclease |
T2204 |
5734-5748 |
JJ |
denotes |
hypersensitive |
T2205 |
5749-5754 |
NN |
denotes |
sites |
T2206 |
5755-5761 |
VB |
denotes |
spread |
T2207 |
5762-5766 |
IN |
denotes |
over |
T2208 |
5767-5769 |
CD |
denotes |
25 |
T2209 |
5770-5772 |
NN |
denotes |
kb |
T2210 |
5773-5780 |
JJ |
denotes |
located |
T2211 |
5781-5783 |
NN |
denotes |
5′ |
T2212 |
5784-5786 |
IN |
denotes |
of |
T2213 |
5787-5790 |
DT |
denotes |
the |
T2214 |
5791-5793 |
JJ |
denotes |
ɛy |
T2215 |
5794-5798 |
NN |
denotes |
gene |
T2216 |
5799-5800 |
-LRB- |
denotes |
[ |
T2217 |
5800-5802 |
CD |
denotes |
23 |
T2218 |
5802-5803 |
-RRB- |
denotes |
] |
T2219 |
5805-5808 |
DT |
denotes |
The |
T2220 |
5809-5817 |
JJ |
denotes |
β-globin |
T2221 |
5818-5823 |
NN |
denotes |
genes |
T2222 |
5824-5827 |
VB |
denotes |
are |
T2223 |
5828-5837 |
VB |
denotes |
expressed |
T2224 |
5838-5840 |
IN |
denotes |
in |
T2225 |
5841-5842 |
DT |
denotes |
a |
T2226 |
5843-5850 |
NN |
denotes |
tissue- |
T2227 |
5851-5854 |
CC |
denotes |
and |
T2228 |
5855-5875 |
JJ |
denotes |
development-specific |
T2229 |
5876-5883 |
NN |
denotes |
fashion |
T2230 |
5885-5887 |
IN |
denotes |
In |
T2231 |
5888-5892 |
NN |
denotes |
mice |
T2232 |
5892-5893 |
-COMMA- |
denotes |
, |
T2233 |
5894-5908 |
NN |
denotes |
erythropoiesis |
T2234 |
5909-5919 |
VB |
denotes |
originates |
T2235 |
5920-5922 |
IN |
denotes |
in |
T2236 |
5923-5926 |
DT |
denotes |
the |
T2237 |
5927-5936 |
JJ |
denotes |
embryonic |
T2238 |
5937-5941 |
NN |
denotes |
yolk |
T2239 |
5942-5945 |
NN |
denotes |
sac |
T2240 |
5946-5951 |
WRB |
denotes |
where |
T2241 |
5952-5961 |
JJ |
denotes |
primitive |
T2242 |
5962-5971 |
JJ |
denotes |
erythroid |
T2243 |
5972-5977 |
NN |
denotes |
cells |
T2244 |
5978-5985 |
VB |
denotes |
express |
T2245 |
5986-5988 |
JJ |
denotes |
ɛy |
T2246 |
5989-5992 |
CC |
denotes |
and |
T2247 |
5993-5997 |
NN |
denotes |
βh-1 |
T2248 |
5998-6005 |
NN |
denotes |
globins |
T2249 |
6006-6007 |
-LRB- |
denotes |
[ |
T2250 |
6007-6009 |
CD |
denotes |
22 |
T2251 |
6009-6010 |
-RRB- |
denotes |
] |
T2252 |
6012-6014 |
IN |
denotes |
At |
T2253 |
6015-6019 |
CD |
denotes |
11.5 |
T2254 |
6020-6021 |
NN |
denotes |
d |
T2255 |
6022-6026 |
NN |
denotes |
post |
T2256 |
6027-6033 |
NN |
denotes |
coitus |
T2257 |
6034-6035 |
-LRB- |
denotes |
( |
T2258 |
6035-6038 |
NN |
denotes |
dpc |
T2259 |
6038-6039 |
-RRB- |
denotes |
) |
T2260 |
6039-6040 |
-COMMA- |
denotes |
, |
T2261 |
6041-6055 |
NN |
denotes |
erythropoiesis |
T2262 |
6056-6062 |
NN |
denotes |
shifts |
T2263 |
6063-6065 |
TO |
denotes |
to |
T2264 |
6066-6069 |
DT |
denotes |
the |
T2265 |
6070-6075 |
JJ |
denotes |
fetal |
T2266 |
6076-6081 |
NN |
denotes |
liver |
T2267 |
6082-6087 |
WRB |
denotes |
where |
T2268 |
6088-6098 |
JJ |
denotes |
definitive |
T2269 |
6099-6108 |
JJ |
denotes |
erythroid |
T2270 |
6109-6114 |
NN |
denotes |
cells |
T2271 |
6115-6122 |
VB |
denotes |
express |
T2272 |
6123-6128 |
JJ |
denotes |
adult |
T2273 |
6129-6130 |
JJ |
denotes |
β |
T2274 |
6131-6138 |
NN |
denotes |
globins |
T2275 |
6139-6140 |
-LRB- |
denotes |
( |
T2276 |
6140-6141 |
VB |
denotes |
β |
T2277 |
6142-6147 |
JJ |
denotes |
major |
T2278 |
6148-6151 |
CC |
denotes |
and |
T2279 |
6152-6157 |
JJ |
denotes |
minor |
T2280 |
6157-6158 |
-RRB- |
denotes |
) |
T2281 |
6159-6160 |
-LRB- |
denotes |
[ |
T2282 |
6160-6162 |
CD |
denotes |
22 |
T2283 |
6162-6163 |
-RRB- |
denotes |
] |
T2284 |
6165-6168 |
DT |
denotes |
The |
T2285 |
6169-6171 |
JJ |
denotes |
ɛy |
T2286 |
6172-6176 |
NN |
denotes |
gene |
T2287 |
6177-6179 |
VB |
denotes |
is |
T2288 |
6180-6188 |
VB |
denotes |
silenced |
T2289 |
6189-6191 |
IN |
denotes |
in |
T2290 |
6192-6202 |
JJ |
denotes |
definitive |
T2291 |
6203-6212 |
JJ |
denotes |
erythroid |
T2292 |
6213-6218 |
NN |
denotes |
cells |
T2293 |
6220-6223 |
DT |
denotes |
The |
T2294 |
6224-6233 |
NN |
denotes |
mechanism |
T2295 |
6234-6236 |
IN |
denotes |
of |
T2296 |
6237-6246 |
NN |
denotes |
silencing |
T2297 |
6247-6249 |
IN |
denotes |
of |
T2298 |
6250-6253 |
PRP-DOLLAR- |
denotes |
its |
T2299 |
6254-6259 |
JJ |
denotes |
human |
T2300 |
6260-6271 |
NN |
denotes |
counterpart |
T2301 |
6271-6272 |
-COMMA- |
denotes |
, |
T2302 |
6273-6274 |
NN |
denotes |
ɛ |
T2303 |
6275-6281 |
NN |
denotes |
globin |
T2304 |
6281-6282 |
-COMMA- |
denotes |
, |
T2305 |
6283-6286 |
VB |
denotes |
has |
T2306 |
6287-6291 |
VB |
denotes |
been |
T2307 |
6292-6299 |
VB |
denotes |
studied |
T2308 |
6300-6311 |
RB |
denotes |
extensively |
T2309 |
6313-6315 |
IN |
denotes |
In |
T2310 |
6316-6326 |
JJ |
denotes |
definitive |
T2311 |
6327-6341 |
NN |
denotes |
erythropoiesis |
T2312 |
6341-6342 |
-COMMA- |
denotes |
, |
T2313 |
6343-6344 |
NN |
denotes |
ɛ |
T2314 |
6345-6347 |
VB |
denotes |
is |
T2315 |
6348-6357 |
VB |
denotes |
activated |
T2316 |
6358-6361 |
CC |
denotes |
and |
T2317 |
6362-6370 |
VB |
denotes |
silenced |
T2318 |
6371-6383 |
RB |
denotes |
autonomously |
T2319 |
6384-6385 |
-LRB- |
denotes |
[ |
T2320 |
6385-6390 |
CD |
denotes |
24,25 |
T2321 |
6390-6391 |
-RRB- |
denotes |
] |
T2322 |
6391-6392 |
-COMMA- |
denotes |
, |
T2323 |
6393-6401 |
IN |
denotes |
although |
T2324 |
6402-6404 |
IN |
denotes |
in |
T2325 |
6405-6414 |
JJ |
denotes |
primitive |
T2326 |
6415-6429 |
NN |
denotes |
erythropoiesis |
T2327 |
6430-6431 |
NN |
denotes |
ɛ |
T2328 |
6432-6436 |
RB |
denotes |
also |
T2329 |
6437-6444 |
VB |
denotes |
appears |
T2330 |
6445-6447 |
TO |
denotes |
to |
T2331 |
6448-6450 |
VB |
denotes |
be |
T2332 |
6451-6460 |
VB |
denotes |
regulated |
T2333 |
6461-6474 |
RB |
denotes |
competitively |
T2334 |
6475-6476 |
-LRB- |
denotes |
[ |
T2335 |
6476-6478 |
CD |
denotes |
26 |
T2336 |
6478-6479 |
-RRB- |
denotes |
] |
T2337 |
6481-6484 |
DT |
denotes |
The |
T2338 |
6485-6493 |
NN |
denotes |
γ-globin |
T2339 |
6494-6496 |
TO |
denotes |
to |
T2340 |
6497-6502 |
JJ |
denotes |
adult |
T2341 |
6503-6511 |
JJ |
denotes |
β-globin |
T2342 |
6512-6518 |
NN |
denotes |
switch |
T2343 |
6519-6521 |
VB |
denotes |
is |
T2344 |
6522-6532 |
VB |
denotes |
controlled |
T2345 |
6533-6535 |
IN |
denotes |
by |
T2346 |
6536-6544 |
NN |
denotes |
promoter |
T2347 |
6545-6556 |
NN |
denotes |
competition |
T2348 |
6557-6560 |
IN |
denotes |
for |
T2349 |
6561-6564 |
DT |
denotes |
the |
T2350 |
6565-6568 |
NN |
denotes |
LCR |
T2351 |
6569-6570 |
-LRB- |
denotes |
[ |
T2352 |
6570-6575 |
CD |
denotes |
24,25 |
T2353 |
6575-6576 |
-RRB- |
denotes |
] |
T2354 |
6578-6581 |
PDT |
denotes |
All |
T2355 |
6582-6585 |
DT |
denotes |
the |
T2356 |
6586-6594 |
NN |
denotes |
elements |
T2357 |
6595-6606 |
JJ |
denotes |
responsible |
T2358 |
6607-6610 |
IN |
denotes |
for |
T2359 |
6611-6620 |
VB |
denotes |
silencing |
T2360 |
6621-6624 |
DT |
denotes |
the |
T2361 |
6625-6626 |
NN |
denotes |
ɛ |
T2362 |
6627-6633 |
NN |
denotes |
globin |
T2363 |
6634-6638 |
NN |
denotes |
gene |
T2364 |
6639-6642 |
VB |
denotes |
are |
T2365 |
6643-6649 |
IN |
denotes |
within |
T2366 |
6650-6653 |
DT |
denotes |
the |
T2367 |
6654-6655 |
NN |
denotes |
ɛ |
T2368 |
6656-6660 |
NN |
denotes |
gene |
T2369 |
6661-6663 |
CC |
denotes |
or |
T2370 |
6664-6666 |
IN |
denotes |
in |
T2371 |
6667-6675 |
JJ |
denotes |
adjacent |
T2372 |
6676-6685 |
NN |
denotes |
sequences |
T2373 |
6686-6687 |
-LRB- |
denotes |
[ |
T2374 |
6687-6689 |
CD |
denotes |
27 |
T2375 |
6689-6690 |
-RRB- |
denotes |
] |
T2376 |
6690-6691 |
-COMMA- |
denotes |
, |
T2377 |
6692-6702 |
VB |
denotes |
suggesting |
T2378 |
6703-6707 |
IN |
denotes |
that |
T2379 |
6708-6717 |
NN |
denotes |
silencing |
T2380 |
6718-6720 |
VB |
denotes |
is |
T2381 |
6721-6730 |
RB |
denotes |
primarily |
T2382 |
6731-6735 |
NN |
denotes |
gene |
T2383 |
6736-6746 |
JJ |
denotes |
autonomous |
T2384 |
6748-6753 |
VB |
denotes |
Using |
T2385 |
6754-6762 |
NN |
denotes |
promoter |
T2386 |
6763-6771 |
NN |
denotes |
deletion |
T2387 |
6772-6780 |
NN |
denotes |
analyses |
T2388 |
6781-6783 |
IN |
denotes |
in |
T2389 |
6784-6794 |
JJ |
denotes |
transgenic |
T2390 |
6795-6800 |
NN |
denotes |
mouse |
T2391 |
6801-6807 |
NN |
denotes |
models |
T2392 |
6808-6811 |
CC |
denotes |
and |
T2393 |
6812-6816 |
NN |
denotes |
cell |
T2394 |
6817-6829 |
NN |
denotes |
transfection |
T2395 |
6830-6836 |
NN |
denotes |
assays |
T2396 |
6836-6837 |
-COMMA- |
denotes |
, |
T2397 |
6838-6846 |
JJ |
denotes |
multiple |
T2398 |
6847-6850 |
NN |
denotes |
DNA |
T2399 |
6851-6859 |
NN |
denotes |
elements |
T2400 |
6860-6869 |
JJ |
denotes |
important |
T2401 |
6870-6872 |
TO |
denotes |
to |
T2402 |
6873-6876 |
DT |
denotes |
the |
T2403 |
6877-6886 |
NN |
denotes |
silencing |
T2404 |
6887-6894 |
NN |
denotes |
process |
T2405 |
6895-6899 |
VB |
denotes |
have |
T2406 |
6900-6904 |
VB |
denotes |
been |
T2407 |
6905-6915 |
RB |
denotes |
previously |
T2408 |
6916-6926 |
VB |
denotes |
identified |
T2409 |
6927-6929 |
IN |
denotes |
in |
T2410 |
6930-6934 |
CC |
denotes |
both |
T2411 |
6935-6938 |
DT |
denotes |
the |
T2412 |
6939-6947 |
JJ |
denotes |
proximal |
T2413 |
6948-6951 |
CC |
denotes |
and |
T2414 |
6952-6955 |
DT |
denotes |
the |
T2415 |
6956-6962 |
JJ |
denotes |
distal |
T2416 |
6963-6964 |
NN |
denotes |
ɛ |
T2417 |
6965-6969 |
NN |
denotes |
gene |
T2418 |
6970-6978 |
NN |
denotes |
promoter |
T2419 |
6979-6980 |
-LRB- |
denotes |
[ |
T2420 |
6980-6982 |
CD |
denotes |
27 |
T2421 |
6982-6983 |
-RRB- |
denotes |
] |
T2422 |
6985-6990 |
PRP-DOLLAR- |
denotes |
Their |
T2423 |
6991-7004 |
JJ |
denotes |
corresponding |
T2424 |
7005-7018 |
NN |
denotes |
transcription |
T2425 |
7019-7026 |
NN |
denotes |
factors |
T2426 |
7026-7027 |
-COMMA- |
denotes |
, |
T2427 |
7028-7032 |
JJ |
denotes |
such |
T2428 |
7033-7035 |
IN |
denotes |
as |
T2429 |
7036-7042 |
NN |
denotes |
GATA-1 |
T2430 |
7042-7043 |
-COMMA- |
denotes |
, |
T2431 |
7044-7048 |
NN |
denotes |
YY-1 |
T2432 |
7048-7049 |
-COMMA- |
denotes |
, |
T2433 |
7050-7057 |
NN |
denotes |
COUP-TF |
T2434 |
7057-7058 |
-COMMA- |
denotes |
, |
T2435 |
7059-7062 |
CC |
denotes |
and |
T2436 |
7063-7067 |
NNP |
denotes |
DRED |
T2437 |
7068-7072 |
VB |
denotes |
have |
T2438 |
7073-7077 |
VB |
denotes |
been |
T2439 |
7078-7088 |
VB |
denotes |
identified |
T2440 |
7089-7092 |
CC |
denotes |
and |
T2441 |
7093-7098 |
VB |
denotes |
shown |
T2442 |
7099-7101 |
TO |
denotes |
to |
T2443 |
7102-7110 |
RB |
denotes |
directly |
T2444 |
7111-7115 |
VB |
denotes |
bind |
T2445 |
7116-7118 |
TO |
denotes |
to |
T2446 |
7119-7124 |
DT |
denotes |
these |
T2447 |
7125-7128 |
NN |
denotes |
DNA |
T2448 |
7129-7137 |
NN |
denotes |
elements |
T2449 |
7138-7139 |
-LRB- |
denotes |
( |
T2450 |
7139-7141 |
IN |
denotes |
as |
T2451 |
7142-7146 |
NN |
denotes |
part |
T2452 |
7147-7149 |
IN |
denotes |
of |
T2453 |
7150-7157 |
NN |
denotes |
protein |
T2454 |
7158-7167 |
NN |
denotes |
complexes |
T2455 |
7167-7168 |
-RRB- |
denotes |
) |
T2456 |
7169-7171 |
TO |
denotes |
to |
T2457 |
7172-7180 |
VB |
denotes |
regulate |
T2458 |
7181-7182 |
RB |
denotes |
ɛ |
T2459 |
7183-7192 |
VB |
denotes |
silencing |
T2460 |
7193-7194 |
-LRB- |
denotes |
[ |
T2461 |
7194-7196 |
CD |
denotes |
27 |
T2462 |
7196-7197 |
-RRB- |
denotes |
] |
T2463 |
7199-7203 |
RB |
denotes |
Thus |
T2464 |
7203-7204 |
-COMMA- |
denotes |
, |
T2465 |
7205-7207 |
PRP |
denotes |
it |
T2466 |
7208-7215 |
VB |
denotes |
appears |
T2467 |
7216-7220 |
IN |
denotes |
that |
T2468 |
7221-7224 |
DT |
denotes |
the |
T2469 |
7225-7234 |
NN |
denotes |
silencing |
T2470 |
7235-7237 |
IN |
denotes |
of |
T2471 |
7238-7241 |
DT |
denotes |
the |
T2472 |
7242-7243 |
NN |
denotes |
ɛ |
T2473 |
7244-7248 |
NN |
denotes |
gene |
T2474 |
7249-7257 |
VB |
denotes |
involves |
T2475 |
7258-7259 |
DT |
denotes |
a |
T2476 |
7260-7271 |
JJ |
denotes |
complicated |
T2477 |
7272-7279 |
NN |
denotes |
network |
T2478 |
7280-7282 |
IN |
denotes |
of |
T2479 |
7283-7291 |
JJ |
denotes |
multiple |
T2480 |
7292-7295 |
NN |
denotes |
cis |
T2481 |
7296-7304 |
NN |
denotes |
elements |
T2482 |
7305-7308 |
CC |
denotes |
and |
T2483 |
7309-7320 |
VB |
denotes |
transacting |
T2484 |
7321-7329 |
NN |
denotes |
proteins |
T2485 |
7331-7333 |
IN |
denotes |
In |
T2486 |
7334-7342 |
NN |
denotes |
addition |
T2487 |
7343-7345 |
TO |
denotes |
to |
T2488 |
7346-7353 |
VB |
denotes |
playing |
T2489 |
7354-7356 |
DT |
denotes |
an |
T2490 |
7357-7366 |
JJ |
denotes |
important |
T2491 |
7367-7371 |
NN |
denotes |
role |
T2492 |
7372-7374 |
IN |
denotes |
in |
T2493 |
7375-7378 |
DT |
denotes |
the |
T2494 |
7379-7390 |
NN |
denotes |
development |
T2495 |
7391-7393 |
IN |
denotes |
of |
T2496 |
7394-7397 |
DT |
denotes |
the |
T2497 |
7398-7405 |
JJ |
denotes |
central |
T2498 |
7406-7413 |
JJ |
denotes |
nervous |
T2499 |
7414-7420 |
NN |
denotes |
system |
T2500 |
7421-7422 |
-LRB- |
denotes |
[ |
T2501 |
7422-7426 |
CD |
denotes |
8–11 |
T2502 |
7426-7427 |
-RRB- |
denotes |
] |
T2503 |
7427-7428 |
-COMMA- |
denotes |
, |
T2504 |
7429-7438 |
NN |
denotes |
cartilage |
T2505 |
7439-7440 |
-LRB- |
denotes |
[ |
T2506 |
7440-7447 |
CD |
denotes |
6,12,13 |
T2507 |
7447-7448 |
-RRB- |
denotes |
] |
T2508 |
7448-7449 |
-COMMA- |
denotes |
, |
T2509 |
7450-7453 |
CC |
denotes |
and |
T2510 |
7454-7460 |
NN |
denotes |
muscle |
T2511 |
7461-7462 |
-LRB- |
denotes |
[ |
T2512 |
7462-7467 |
CD |
denotes |
14,15 |
T2513 |
7467-7468 |
-RRB- |
denotes |
] |
T2514 |
7468-7469 |
-COMMA- |
denotes |
, |
T2515 |
7470-7472 |
PRP |
denotes |
it |
T2516 |
7473-7476 |
VB |
denotes |
was |
T2517 |
7477-7482 |
VB |
denotes |
shown |
T2518 |
7483-7487 |
IN |
denotes |
that |
T2519 |
7488-7492 |
NN |
denotes |
Sox6 |
T2520 |
7493-7495 |
VB |
denotes |
is |
T2521 |
7496-7507 |
VB |
denotes |
upregulated |
T2522 |
7508-7510 |
IN |
denotes |
in |
T2523 |
7511-7520 |
JJ |
denotes |
long-term |
T2524 |
7521-7534 |
NN |
denotes |
hematopoiesis |
T2525 |
7535-7539 |
NN |
denotes |
stem |
T2526 |
7540-7545 |
NN |
denotes |
cells |
T2527 |
7546-7547 |
-LRB- |
denotes |
( |
T2528 |
7547-7553 |
NN |
denotes |
LT-HSC |
T2529 |
7553-7554 |
-RRB- |
denotes |
) |
T2530 |
7555-7563 |
VB |
denotes |
compared |
T2531 |
7564-7568 |
IN |
denotes |
with |
T2532 |
7569-7580 |
JJ |
denotes |
multipotent |
T2533 |
7581-7592 |
NN |
denotes |
progenitors |
T2534 |
7593-7595 |
IN |
denotes |
of |
T2535 |
7596-7601 |
JJ |
denotes |
adult |
T2536 |
7602-7607 |
NN |
denotes |
mouse |
T2537 |
7608-7612 |
NN |
denotes |
bone |
T2538 |
7613-7619 |
NN |
denotes |
marrow |
T2539 |
7620-7627 |
NN |
denotes |
lineage |
T2540 |
7628-7629 |
-LRB- |
denotes |
[ |
T2541 |
7629-7631 |
CD |
denotes |
28 |
T2542 |
7631-7632 |
-RRB- |
denotes |
] |
T2543 |
7634-7636 |
IN |
denotes |
In |
T2544 |
7637-7641 |
DT |
denotes |
this |
T2545 |
7642-7647 |
NN |
denotes |
study |
T2546 |
7647-7648 |
-COMMA- |
denotes |
, |
T2547 |
7649-7651 |
PRP |
denotes |
we |
T2548 |
7652-7660 |
VB |
denotes |
describe |
T2549 |
7661-7665 |
IN |
denotes |
that |
T2550 |
7666-7670 |
NN |
denotes |
Sox6 |
T2551 |
7671-7675 |
RB |
denotes |
also |
T2552 |
7676-7682 |
VB |
denotes |
exerts |
T2553 |
7683-7694 |
JJ |
denotes |
pleiotropic |
T2554 |
7695-7702 |
NN |
denotes |
effects |
T2555 |
7703-7705 |
IN |
denotes |
on |
T2556 |
7706-7720 |
NN |
denotes |
erythropoiesis |
T2557 |
7722-7727 |
DT |
denotes |
These |
T2558 |
7728-7735 |
NN |
denotes |
effects |
T2559 |
7736-7743 |
VB |
denotes |
include |
T2560 |
7744-7751 |
VB |
denotes |
delayed |
T2561 |
7752-7762 |
NN |
denotes |
maturation |
T2562 |
7763-7765 |
IN |
denotes |
of |
T2563 |
7766-7778 |
NN |
denotes |
erythrocytes |
T2564 |
7779-7780 |
-LRB- |
denotes |
( |
T2565 |
7780-7784 |
IN |
denotes |
that |
T2566 |
7785-7793 |
RB |
denotes |
normally |
T2567 |
7794-7803 |
VB |
denotes |
enucleate |
T2568 |
7804-7809 |
JJ |
denotes |
prior |
T2569 |
7810-7812 |
TO |
denotes |
to |
T2570 |
7813-7821 |
VB |
denotes |
entering |
T2571 |
7822-7825 |
DT |
denotes |
the |
T2572 |
7826-7837 |
NN |
denotes |
bloodstream |
T2573 |
7838-7839 |
-LRB- |
denotes |
[ |
T2574 |
7839-7841 |
CD |
denotes |
27 |
T2575 |
7841-7842 |
-RRB- |
denotes |
] |
T2576 |
7842-7843 |
-RRB- |
denotes |
) |
T2577 |
7844-7847 |
CC |
denotes |
and |
T2578 |
7848-7854 |
JJ |
denotes |
higher |
T2579 |
7855-7865 |
NN |
denotes |
expression |
T2580 |
7866-7868 |
IN |
denotes |
of |
T2581 |
7869-7878 |
JJ |
denotes |
embryonic |
T2582 |
7879-7885 |
NN |
denotes |
globin |
T2583 |
7886-7891 |
NN |
denotes |
genes |
T2584 |
7893-7896 |
DT |
denotes |
The |
T2585 |
7897-7901 |
RB |
denotes |
most |
T2586 |
7902-7909 |
JJ |
denotes |
extreme |
T2587 |
7910-7916 |
NN |
denotes |
effect |
T2588 |
7917-7919 |
VB |
denotes |
is |
T2589 |
7920-7923 |
DT |
denotes |
the |
T2590 |
7924-7935 |
NN |
denotes |
persistence |
T2591 |
7936-7938 |
IN |
denotes |
of |
T2592 |
7939-7943 |
JJ |
denotes |
high |
T2593 |
7944-7954 |
NN |
denotes |
expression |
T2594 |
7955-7957 |
IN |
denotes |
of |
T2595 |
7958-7961 |
DT |
denotes |
the |
T2596 |
7962-7971 |
JJ |
denotes |
embryonic |
T2597 |
7972-7974 |
JJ |
denotes |
ɛy |
T2598 |
7975-7981 |
NN |
denotes |
globin |
T2599 |
7982-7986 |
NN |
denotes |
gene |
T2600 |
7988-7992 |
RB |
denotes |
Here |
T2601 |
7993-7995 |
PRP |
denotes |
we |
T2602 |
7996-8004 |
VB |
denotes |
describe |
T2603 |
8005-8008 |
CC |
denotes |
and |
T2604 |
8009-8021 |
VB |
denotes |
characterize |
T2605 |
8022-8025 |
DT |
denotes |
the |
T2606 |
8026-8033 |
NN |
denotes |
effects |
T2607 |
8034-8036 |
IN |
denotes |
of |
T2608 |
8037-8041 |
NN |
denotes |
Sox6 |
T2609 |
8042-8044 |
IN |
denotes |
on |
T2610 |
8045-8048 |
DT |
denotes |
the |
T2611 |
8049-8051 |
JJ |
denotes |
ɛy |
T2612 |
8052-8058 |
NN |
denotes |
globin |
T2613 |
8059-8063 |
NN |
denotes |
gene |
T2614 |
8065-8067 |
PRP |
denotes |
We |
T2615 |
8068-8072 |
VB |
denotes |
show |
T2616 |
8073-8077 |
IN |
denotes |
that |
T2617 |
8078-8082 |
NN |
denotes |
Sox6 |
T2618 |
8083-8088 |
VB |
denotes |
binds |
T2619 |
8089-8091 |
TO |
denotes |
to |
T2620 |
8092-8095 |
DT |
denotes |
the |
T2621 |
8096-8104 |
JJ |
denotes |
proximal |
T2622 |
8105-8113 |
NN |
denotes |
promoter |
T2623 |
8114-8116 |
IN |
denotes |
of |
T2624 |
8117-8119 |
JJ |
denotes |
ɛy |
T2625 |
8120-8126 |
NN |
denotes |
globin |
T2626 |
8127-8130 |
CC |
denotes |
and |
T2627 |
8131-8140 |
VB |
denotes |
represses |
T2628 |
8141-8144 |
PRP-DOLLAR- |
denotes |
its |
T2629 |
8145-8158 |
NN |
denotes |
transcription |
T2630 |
8160-8162 |
IN |
denotes |
In |
T2631 |
8163-8172 |
JJ |
denotes |
wild-type |
T2632 |
8173-8174 |
-LRB- |
denotes |
( |
T2633 |
8174-8176 |
JJ |
denotes |
WT |
T2634 |
8176-8177 |
-RRB- |
denotes |
) |
T2635 |
8178-8182 |
NN |
denotes |
mice |
T2636 |
8182-8183 |
-COMMA- |
denotes |
, |
T2637 |
8184-8188 |
NN |
denotes |
Sox6 |
T2638 |
8189-8191 |
VB |
denotes |
is |
T2639 |
8192-8195 |
RB |
denotes |
not |
T2640 |
8196-8205 |
VB |
denotes |
expressed |
T2641 |
8206-8208 |
IN |
denotes |
in |
T2642 |
8209-8213 |
NN |
denotes |
yolk |
T2643 |
8214-8217 |
NN |
denotes |
sac |
T2644 |
8218-8223 |
NN |
denotes |
blood |
T2645 |
8224-8231 |
NN |
denotes |
islands |
T2646 |
8231-8232 |
-COMMA- |
denotes |
, |
T2647 |
8233-8236 |
CC |
denotes |
but |
T2648 |
8237-8239 |
VB |
denotes |
is |
T2649 |
8240-8249 |
VB |
denotes |
expressed |
T2650 |
8250-8252 |
IN |
denotes |
in |
T2651 |
8253-8258 |
JJ |
denotes |
fetal |
T2652 |
8259-8264 |
NN |
denotes |
liver |
T2653 |
8264-8265 |
-COMMA- |
denotes |
, |
T2654 |
8266-8269 |
DT |
denotes |
the |
T2655 |
8270-8278 |
JJ |
denotes |
opposite |
T2656 |
8279-8289 |
NN |
denotes |
expression |
T2657 |
8290-8297 |
NN |
denotes |
pattern |
T2658 |
8298-8300 |
IN |
denotes |
of |
T2659 |
8301-8303 |
JJ |
denotes |
ɛy |
T2660 |
8304-8310 |
NN |
denotes |
globin |
T2661 |
8312-8314 |
IN |
denotes |
In |
T2662 |
8315-8318 |
DT |
denotes |
the |
T2663 |
8319-8326 |
NN |
denotes |
absence |
T2664 |
8327-8329 |
IN |
denotes |
of |
T2665 |
8330-8334 |
NN |
denotes |
Sox6 |
T2666 |
8334-8335 |
-COMMA- |
denotes |
, |
T2667 |
8336-8338 |
JJ |
denotes |
ɛy |
T2668 |
8339-8345 |
NN |
denotes |
globin |
T2669 |
8346-8348 |
VB |
denotes |
is |
T2670 |
8349-8360 |
RB |
denotes |
ectopically |
T2671 |
8361-8370 |
VB |
denotes |
expressed |
T2672 |
8371-8373 |
IN |
denotes |
in |
T2673 |
8374-8377 |
DT |
denotes |
the |
T2674 |
8378-8383 |
JJ |
denotes |
fetal |
T2675 |
8384-8389 |
NN |
denotes |
liver |
T2676 |
8389-8390 |
-COMMA- |
denotes |
, |
T2677 |
8391-8404 |
VB |
denotes |
demonstrating |
T2678 |
8405-8409 |
IN |
denotes |
that |
T2679 |
8410-8414 |
NN |
denotes |
Sox6 |
T2680 |
8415-8424 |
NN |
denotes |
functions |
T2681 |
8425-8427 |
IN |
denotes |
in |
T2682 |
8428-8438 |
JJ |
denotes |
definitive |
T2683 |
8439-8453 |
NN |
denotes |
erythropoiesis |
T4527 |
8465-8475 |
JJ |
denotes |
Persistent |
T4528 |
8476-8486 |
NN |
denotes |
Expression |
T4529 |
8487-8489 |
IN |
denotes |
of |
T4530 |
8490-8493 |
DT |
denotes |
the |
T4531 |
8494-8503 |
NNP |
denotes |
Embryonic |
T4532 |
8504-8510 |
NNP |
denotes |
Globin |
T4533 |
8510-8511 |
-COMMA- |
denotes |
, |
T4534 |
8512-8514 |
NNP |
denotes |
ɛy |
T4535 |
8514-8515 |
-COMMA- |
denotes |
, |
T4536 |
8516-8518 |
IN |
denotes |
in |
T4537 |
8519-8533 |
JJ |
denotes |
Sox6-Deficient |
T4538 |
8534-8538 |
NN |
denotes |
Mice |
T4539 |
8539-8542 |
DT |
denotes |
The |
T4540 |
8543-8545 |
JJ |
denotes |
ɛy |
T4541 |
8546-8552 |
NN |
denotes |
globin |
T4542 |
8553-8557 |
NN |
denotes |
gene |
T4543 |
8558-8561 |
VB |
denotes |
was |
T4544 |
8562-8571 |
RB |
denotes |
initially |
T4545 |
8572-8582 |
VB |
denotes |
identified |
T4546 |
8583-8585 |
IN |
denotes |
as |
T4547 |
8586-8588 |
DT |
denotes |
an |
T4548 |
8589-8600 |
VB |
denotes |
upregulated |
T4549 |
8601-8611 |
NN |
denotes |
transcript |
T4550 |
8612-8614 |
IN |
denotes |
in |
T4551 |
8615-8618 |
DT |
denotes |
the |
T4552 |
8619-8625 |
NN |
denotes |
p 100H |
T4553 |
8626-8631 |
NN |
denotes |
mouse |
T4554 |
8632-8637 |
VB |
denotes |
using |
T4555 |
8638-8649 |
JJ |
denotes |
subtractive |
T4556 |
8650-8663 |
NN |
denotes |
hybridization |
T4557 |
8664-8666 |
TO |
denotes |
to |
T4558 |
8667-8675 |
VB |
denotes |
identify |
T4559 |
8676-8680 |
NN |
denotes |
Sox6 |
T4560 |
8681-8691 |
JJ |
denotes |
downstream |
T4561 |
8692-8699 |
NN |
denotes |
targets |
T4562 |
8701-8705 |
DT |
denotes |
This |
T4563 |
8706-8713 |
JJ |
denotes |
initial |
T4564 |
8714-8725 |
NN |
denotes |
observation |
T4565 |
8726-8729 |
VB |
denotes |
was |
T4566 |
8730-8739 |
VB |
denotes |
confirmed |
T4567 |
8740-8742 |
IN |
denotes |
in |
T4568 |
8743-8745 |
DT |
denotes |
an |
T4569 |
8746-8757 |
JJ |
denotes |
independent |
T4570 |
8758-8767 |
JJ |
denotes |
knock-out |
T4571 |
8768-8774 |
NN |
denotes |
allele |
T4572 |
8775-8777 |
IN |
denotes |
of |
T4573 |
8778-8782 |
NN |
denotes |
Sox6 |
T4574 |
8783-8784 |
-LRB- |
denotes |
[ |
T4575 |
8784-8786 |
CD |
denotes |
13 |
T4576 |
8786-8787 |
-RRB- |
denotes |
] |
T4577 |
8788-8793 |
VB |
denotes |
using |
T4578 |
8794-8803 |
JJ |
denotes |
real-time |
T4579 |
8804-8814 |
NN |
denotes |
polymerase |
T4580 |
8815-8820 |
NN |
denotes |
chain |
T4581 |
8821-8829 |
NN |
denotes |
reaction |
T4582 |
8830-8831 |
-LRB- |
denotes |
( |
T4583 |
8831-8834 |
NN |
denotes |
PCR |
T4584 |
8834-8835 |
-RRB- |
denotes |
) |
T4585 |
8836-8837 |
-LRB- |
denotes |
( |
T4586 |
8837-8848 |
JJ |
denotes |
unpublished |
T4587 |
8849-8853 |
NN |
denotes |
data |
T4588 |
8853-8854 |
-RRB- |
denotes |
) |
T4589 |
8856-8865 |
JJ |
denotes |
Real-time |
T4590 |
8866-8869 |
NN |
denotes |
PCR |
T4591 |
8870-8873 |
VB |
denotes |
was |
T4592 |
8874-8878 |
VB |
denotes |
used |
T4593 |
8879-8881 |
TO |
denotes |
to |
T4594 |
8882-8892 |
VB |
denotes |
quantitate |
T4595 |
8893-8896 |
DT |
denotes |
the |
T4596 |
8897-8907 |
NN |
denotes |
expression |
T4597 |
8908-8914 |
NN |
denotes |
levels |
T4598 |
8915-8917 |
IN |
denotes |
of |
T4599 |
8918-8923 |
JJ |
denotes |
other |
T4600 |
8924-8930 |
NN |
denotes |
globin |
T4601 |
8931-8936 |
NN |
denotes |
genes |
T4602 |
8937-8939 |
IN |
denotes |
in |
T4603 |
8940-8945 |
NN |
denotes |
p100H |
T4604 |
8946-8952 |
NN |
denotes |
mutant |
T4605 |
8953-8956 |
CC |
denotes |
and |
T4606 |
8957-8959 |
JJ |
denotes |
WT |
T4607 |
8960-8965 |
NN |
denotes |
mouse |
T4608 |
8966-8972 |
NN |
denotes |
livers |
T4609 |
8973-8975 |
IN |
denotes |
at |
T4610 |
8976-8979 |
CD |
denotes |
two |
T4611 |
8980-8993 |
JJ |
denotes |
developmental |
T4612 |
8994-9000 |
NN |
denotes |
stages |
T4613 |
9000-9001 |
-COMMA- |
denotes |
, |
T4614 |
9002-9006 |
CD |
denotes |
15.5 |
T4615 |
9007-9010 |
NN |
denotes |
dpc |
T4616 |
9011-9014 |
CC |
denotes |
and |
T4617 |
9015-9019 |
CD |
denotes |
18.5 |
T4618 |
9020-9023 |
NN |
denotes |
dpc |
T4619 |
9025-9027 |
IN |
denotes |
As |
T4620 |
9028-9033 |
VB |
denotes |
shown |
T4621 |
9034-9036 |
IN |
denotes |
in |
T4622 |
9037-9043 |
NN |
denotes |
Figure |
T4623 |
9044-9045 |
CD |
denotes |
1 |
T4624 |
9045-9046 |
-COMMA- |
denotes |
, |
T4625 |
9047-9050 |
DT |
denotes |
the |
T4626 |
9051-9053 |
JJ |
denotes |
ɛy |
T4627 |
9054-9058 |
NN |
denotes |
gene |
T4628 |
9059-9061 |
VB |
denotes |
is |
T4629 |
9062-9071 |
VB |
denotes |
expressed |
T4630 |
9072-9074 |
IN |
denotes |
at |
T4631 |
9075-9079 |
JJ |
denotes |
high |
T4632 |
9080-9086 |
NN |
denotes |
levels |
T4633 |
9087-9089 |
IN |
denotes |
at |
T4634 |
9090-9094 |
DT |
denotes |
both |
T4635 |
9095-9099 |
NN |
denotes |
time |
T4636 |
9100-9106 |
NN |
denotes |
points |
T4637 |
9107-9109 |
IN |
denotes |
in |
T4638 |
9110-9116 |
JJ |
denotes |
mutant |
T4639 |
9117-9121 |
NN |
denotes |
mice |
T4640 |
9121-9122 |
-COMMA- |
denotes |
, |
T4641 |
9123-9125 |
IN |
denotes |
in |
T4642 |
9126-9134 |
NN |
denotes |
contrast |
T4643 |
9135-9137 |
TO |
denotes |
to |
T4644 |
9138-9141 |
DT |
denotes |
the |
T4645 |
9142-9149 |
NN |
denotes |
decline |
T4646 |
9150-9152 |
IN |
denotes |
in |
T4647 |
9153-9163 |
NN |
denotes |
expression |
T4648 |
9164-9172 |
VB |
denotes |
observed |
T4649 |
9173-9175 |
IN |
denotes |
in |
T4650 |
9176-9178 |
JJ |
denotes |
WT |
T4651 |
9179-9183 |
NN |
denotes |
mice |
T4652 |
9185-9187 |
DT |
denotes |
No |
T4653 |
9188-9198 |
NN |
denotes |
difference |
T4654 |
9199-9202 |
VB |
denotes |
was |
T4655 |
9203-9207 |
VB |
denotes |
seen |
T4656 |
9208-9215 |
IN |
denotes |
between |
T4657 |
9216-9218 |
NN |
denotes |
WT |
T4658 |
9219-9222 |
CC |
denotes |
and |
T4659 |
9223-9235 |
JJ |
denotes |
heterozygous |
T4660 |
9236-9240 |
NN |
denotes |
mice |
T4661 |
9241-9242 |
-LRB- |
denotes |
( |
T4662 |
9242-9253 |
JJ |
denotes |
unpublished |
T4663 |
9254-9258 |
NN |
denotes |
data |
T4664 |
9258-9259 |
-RRB- |
denotes |
) |
T4665 |
9261-9274 |
RB |
denotes |
Interestingly |
T4666 |
9274-9275 |
-COMMA- |
denotes |
, |
T4667 |
9276-9279 |
DT |
denotes |
the |
T4668 |
9280-9290 |
NN |
denotes |
expression |
T4669 |
9291-9297 |
NN |
denotes |
levels |
T4670 |
9298-9300 |
IN |
denotes |
of |
T4671 |
9301-9304 |
DT |
denotes |
the |
T4672 |
9305-9310 |
JJ |
denotes |
other |
T4673 |
9311-9314 |
CD |
denotes |
two |
T4674 |
9315-9324 |
JJ |
denotes |
embryonic |
T4675 |
9325-9331 |
NN |
denotes |
globin |
T4676 |
9332-9337 |
NN |
denotes |
genes |
T4677 |
9338-9339 |
-LRB- |
denotes |
( |
T4678 |
9339-9340 |
NN |
denotes |
ζ |
T4679 |
9341-9344 |
CC |
denotes |
and |
T4680 |
9345-9348 |
NN |
denotes |
βh1 |
T4681 |
9348-9349 |
-RRB- |
denotes |
) |
T4682 |
9350-9353 |
VB |
denotes |
are |
T4683 |
9354-9358 |
RB |
denotes |
also |
T4684 |
9359-9365 |
JJ |
denotes |
higher |
T4685 |
9366-9368 |
IN |
denotes |
in |
T4686 |
9369-9374 |
NN |
denotes |
p100H |
T4687 |
9375-9385 |
JJ |
denotes |
homozygous |
T4688 |
9386-9390 |
NN |
denotes |
mice |
T4689 |
9390-9391 |
-COMMA- |
denotes |
, |
T4690 |
9392-9400 |
VB |
denotes |
compared |
T4691 |
9401-9405 |
IN |
denotes |
with |
T4692 |
9406-9408 |
JJ |
denotes |
WT |
T4693 |
9409-9413 |
NN |
denotes |
mice |
T4694 |
9413-9414 |
-COMMA- |
denotes |
, |
T4695 |
9415-9418 |
CC |
denotes |
but |
T4696 |
9419-9421 |
TO |
denotes |
to |
T4697 |
9422-9423 |
DT |
denotes |
a |
T4698 |
9424-9428 |
RB |
denotes |
much |
T4699 |
9429-9435 |
JJ |
denotes |
lesser |
T4700 |
9436-9442 |
NN |
denotes |
extent |
T4701 |
9443-9447 |
IN |
denotes |
than |
T4702 |
9448-9452 |
VB |
denotes |
seen |
T4703 |
9453-9456 |
IN |
denotes |
for |
T4704 |
9457-9459 |
JJ |
denotes |
ɛy |
T4705 |
9460-9466 |
NN |
denotes |
globin |
T4706 |
9467-9469 |
IN |
denotes |
at |
T4707 |
9470-9474 |
CD |
denotes |
18.5 |
T4708 |
9475-9478 |
NN |
denotes |
dpc |
T4709 |
9479-9480 |
-LRB- |
denotes |
( |
T4710 |
9480-9486 |
NN |
denotes |
Figure |
T4711 |
9487-9488 |
CD |
denotes |
1 |
T4712 |
9488-9489 |
-RRB- |
denotes |
) |
T4713 |
9491-9499 |
RB |
denotes |
Moreover |
T4714 |
9499-9500 |
-COMMA- |
denotes |
, |
T4715 |
9501-9504 |
DT |
denotes |
the |
T4716 |
9505-9515 |
NN |
denotes |
expression |
T4717 |
9516-9521 |
NN |
denotes |
level |
T4718 |
9522-9524 |
IN |
denotes |
of |
T4719 |
9525-9530 |
JJ |
denotes |
adult |
T4720 |
9531-9532 |
NN |
denotes |
β |
T4721 |
9533-9539 |
NN |
denotes |
globin |
T4722 |
9540-9542 |
VB |
denotes |
is |
T4723 |
9543-9547 |
RB |
denotes |
also |
T4724 |
9548-9556 |
RB |
denotes |
somewhat |
T4725 |
9557-9563 |
JJ |
denotes |
higher |
T4726 |
9564-9566 |
IN |
denotes |
in |
T4727 |
9567-9572 |
NN |
denotes |
p100H |
T4728 |
9573-9583 |
JJ |
denotes |
homozygous |
T4729 |
9584-9588 |
NN |
denotes |
mice |
T4730 |
9589-9593 |
IN |
denotes |
than |
T4731 |
9594-9596 |
IN |
denotes |
in |
T4732 |
9597-9599 |
JJ |
denotes |
WT |
T4733 |
9600-9604 |
NN |
denotes |
mice |
T4734 |
9605-9607 |
IN |
denotes |
at |
T4735 |
9608-9612 |
CD |
denotes |
18.5 |
T4736 |
9613-9616 |
NN |
denotes |
dpc |
T4737 |
9617-9618 |
-LRB- |
denotes |
( |
T4738 |
9618-9624 |
NN |
denotes |
Figure |
T4739 |
9625-9626 |
CD |
denotes |
1 |
T4740 |
9626-9627 |
-RRB- |
denotes |
) |
T4741 |
9629-9638 |
JJ |
denotes |
Perinatal |
T4742 |
9639-9648 |
NN |
denotes |
lethality |
T4743 |
9649-9651 |
IN |
denotes |
of |
T4744 |
9652-9658 |
JJ |
denotes |
mutant |
T4745 |
9659-9663 |
NN |
denotes |
mice |
T4746 |
9664-9665 |
-LRB- |
denotes |
( |
T4747 |
9665-9675 |
RB |
denotes |
presumably |
T4748 |
9676-9680 |
IN |
denotes |
from |
T4749 |
9681-9684 |
DT |
denotes |
the |
T4750 |
9685-9690 |
NN |
denotes |
heart |
T4751 |
9691-9697 |
NN |
denotes |
defect |
T4752 |
9698-9699 |
-LRB- |
denotes |
[ |
T4753 |
9699-9701 |
CD |
denotes |
14 |
T4754 |
9701-9702 |
-RRB- |
denotes |
] |
T4755 |
9702-9703 |
-RRB- |
denotes |
) |
T4756 |
9704-9713 |
VB |
denotes |
precludes |
T4757 |
9714-9716 |
PRP |
denotes |
us |
T4758 |
9717-9721 |
IN |
denotes |
from |
T4759 |
9722-9732 |
VB |
denotes |
evaluating |
T4760 |
9733-9742 |
JJ |
denotes |
postnatal |
T4761 |
9743-9749 |
NN |
denotes |
globin |
T4762 |
9750-9760 |
NN |
denotes |
expression |
T4763 |
9762-9765 |
DT |
denotes |
The |
T4764 |
9766-9772 |
NN |
denotes |
graphs |
T4765 |
9773-9775 |
IN |
denotes |
in |
T4766 |
9776-9782 |
NN |
denotes |
Figure |
T4767 |
9783-9784 |
CD |
denotes |
1 |
T4768 |
9785-9795 |
NN |
denotes |
illustrate |
T4769 |
9796-9800 |
JJ |
denotes |
real |
T4770 |
9801-9805 |
NN |
denotes |
time |
T4771 |
9806-9809 |
NN |
denotes |
PCR |
T4772 |
9810-9817 |
NN |
denotes |
results |
T4773 |
9818-9822 |
WDT |
denotes |
that |
T4774 |
9823-9827 |
VB |
denotes |
were |
T4775 |
9828-9837 |
VB |
denotes |
performed |
T4776 |
9838-9840 |
IN |
denotes |
in |
T4777 |
9841-9851 |
NN |
denotes |
triplicate |
T4778 |
9852-9853 |
-LRB- |
denotes |
( |
T4779 |
9853-9861 |
JJ |
denotes |
standard |
T4780 |
9862-9871 |
NN |
denotes |
deviation |
T4781 |
9872-9874 |
IN |
denotes |
of |
T4782 |
9875-9878 |
DT |
denotes |
the |
T4783 |
9879-9883 |
NN |
denotes |
data |
T4784 |
9884-9886 |
VB |
denotes |
is |
T4785 |
9887-9892 |
VB |
denotes |
shown |
T4786 |
9893-9895 |
IN |
denotes |
by |
T4787 |
9896-9901 |
NN |
denotes |
error |
T4788 |
9902-9906 |
NN |
denotes |
bars |
T4789 |
9906-9907 |
-RRB- |
denotes |
) |
T4790 |
9909-9916 |
IN |
denotes |
Because |
T4791 |
9917-9920 |
DT |
denotes |
all |
T4792 |
9921-9923 |
IN |
denotes |
of |
T4793 |
9924-9927 |
DT |
denotes |
the |
T4794 |
9928-9934 |
NN |
denotes |
assays |
T4795 |
9935-9939 |
VB |
denotes |
were |
T4796 |
9940-9949 |
VB |
denotes |
performed |
T4797 |
9950-9952 |
IN |
denotes |
at |
T4798 |
9953-9956 |
DT |
denotes |
the |
T4799 |
9957-9961 |
JJ |
denotes |
same |
T4800 |
9962-9966 |
NN |
denotes |
time |
T4801 |
9967-9971 |
IN |
denotes |
with |
T4802 |
9972-9975 |
DT |
denotes |
the |
T4803 |
9976-9980 |
JJ |
denotes |
same |
T4804 |
9981-9989 |
JJ |
denotes |
internal |
T4805 |
9990-9997 |
NN |
denotes |
control |
T4806 |
9997-9998 |
-COMMA- |
denotes |
, |
T4807 |
9999-10002 |
DT |
denotes |
the |
T4808 |
10003-10009 |
NN |
denotes |
levels |
T4809 |
10010-10015 |
VB |
denotes |
shown |
T4810 |
10016-10019 |
VB |
denotes |
are |
T4811 |
10020-10028 |
JJ |
denotes |
relative |
T4812 |
10029-10035 |
NN |
denotes |
levels |
T4813 |
10036-10039 |
CC |
denotes |
and |
T4814 |
10040-10043 |
VB |
denotes |
are |
T4815 |
10044-10048 |
RB |
denotes |
thus |
T4816 |
10049-10059 |
JJ |
denotes |
comparable |
T4817 |
10060-10066 |
IN |
denotes |
across |
T4818 |
10067-10070 |
DT |
denotes |
all |
T4819 |
10071-10078 |
NN |
denotes |
samples |
T4820 |
10079-10082 |
CC |
denotes |
and |
T4821 |
10083-10086 |
VB |
denotes |
are |
T4822 |
10087-10089 |
IN |
denotes |
in |
T4823 |
10090-10099 |
NN |
denotes |
agreement |
T4824 |
10100-10104 |
IN |
denotes |
with |
T4825 |
10105-10115 |
RB |
denotes |
previously |
T4826 |
10116-10125 |
VB |
denotes |
published |
T4827 |
10126-10133 |
NN |
denotes |
results |
T4828 |
10134-10137 |
IN |
denotes |
for |
T4829 |
10138-10140 |
JJ |
denotes |
WT |
T4830 |
10141-10146 |
JJ |
denotes |
fetal |
T4831 |
10147-10151 |
NN |
denotes |
mice |
T4832 |
10152-10153 |
-LRB- |
denotes |
[ |
T4833 |
10153-10155 |
CD |
denotes |
29 |
T4834 |
10155-10156 |
-RRB- |
denotes |
] |
T4835 |
10158-10160 |
PRP |
denotes |
We |
T4836 |
10161-10165 |
VB |
denotes |
note |
T4837 |
10166-10170 |
IN |
denotes |
that |
T4838 |
10171-10174 |
DT |
denotes |
the |
T4839 |
10175-10180 |
NN |
denotes |
level |
T4840 |
10181-10183 |
IN |
denotes |
of |
T4841 |
10184-10186 |
JJ |
denotes |
ɛy |
T4842 |
10187-10197 |
NN |
denotes |
expression |
T4843 |
10198-10200 |
IN |
denotes |
in |
T4844 |
10201-10204 |
DT |
denotes |
the |
T4845 |
10205-10211 |
NN |
denotes |
livers |
T4846 |
10212-10214 |
IN |
denotes |
of |
T4847 |
10215-10219 |
CD |
denotes |
15.5 |
T4848 |
10220-10223 |
NN |
denotes |
dpc |
T4849 |
10224-10227 |
CC |
denotes |
and |
T4850 |
10228-10232 |
CD |
denotes |
18.5 |
T4851 |
10233-10236 |
NN |
denotes |
dpc |
T4852 |
10237-10247 |
JJ |
denotes |
homozygous |
T4853 |
10248-10254 |
JJ |
denotes |
mutant |
T4854 |
10255-10259 |
NN |
denotes |
mice |
T4855 |
10260-10262 |
VB |
denotes |
is |
T4856 |
10263-10276 |
RB |
denotes |
statistically |
T4857 |
10277-10287 |
JJ |
denotes |
equivalent |
T4858 |
10288-10290 |
TO |
denotes |
to |
T4859 |
10291-10294 |
DT |
denotes |
the |
T4860 |
10295-10300 |
NN |
denotes |
level |
T4861 |
10301-10303 |
IN |
denotes |
of |
T4862 |
10304-10312 |
NN |
denotes |
βmaj/min |
T4863 |
10313-10323 |
NN |
denotes |
expression |
T4864 |
10324-10326 |
IN |
denotes |
in |
T4865 |
10327-10330 |
DT |
denotes |
the |
T4866 |
10331-10337 |
NN |
denotes |
livers |
T4867 |
10338-10340 |
IN |
denotes |
of |
T4868 |
10341-10345 |
CD |
denotes |
15.5 |
T4869 |
10346-10349 |
NN |
denotes |
dpc |
T4870 |
10350-10353 |
CC |
denotes |
and |
T4871 |
10354-10358 |
CD |
denotes |
18.5 |
T4872 |
10359-10362 |
NN |
denotes |
dpc |
T4873 |
10363-10373 |
JJ |
denotes |
homozygous |
T4874 |
10374-10376 |
JJ |
denotes |
WT |
T4875 |
10377-10381 |
NN |
denotes |
mice |
T5816 |
10796-10808 |
NN |
denotes |
Transfection |
T5817 |
10809-10816 |
NN |
denotes |
Studies |
T5818 |
10817-10822 |
VB |
denotes |
Using |
T5819 |
10823-10828 |
NN |
denotes |
GM979 |
T5820 |
10829-10834 |
NNP |
denotes |
Cells |
T5821 |
10835-10843 |
NNP |
denotes |
Indicate |
T5822 |
10844-10848 |
DT |
denotes |
That |
T5823 |
10849-10853 |
NN |
denotes |
Sox6 |
T5824 |
10854-10862 |
RB |
denotes |
Directly |
T5825 |
10863-10872 |
VB |
denotes |
Represses |
T5826 |
10873-10876 |
DT |
denotes |
the |
T5827 |
10877-10879 |
JJ |
denotes |
ɛy |
T5828 |
10880-10884 |
NN |
denotes |
Gene |
T5829 |
10885-10893 |
NN |
denotes |
Promoter |
T5830 |
10894-10896 |
IN |
denotes |
at |
T5831 |
10897-10900 |
DT |
denotes |
the |
T5832 |
10901-10916 |
NNP |
denotes |
Transcriptional |
T5833 |
10917-10922 |
NNP |
denotes |
Level |
T5834 |
10923-10932 |
JJ |
denotes |
Real-time |
T5835 |
10933-10936 |
NN |
denotes |
PCR |
T5836 |
10937-10943 |
NN |
denotes |
assays |
T5837 |
10944-10945 |
-LRB- |
denotes |
( |
T5838 |
10945-10951 |
NN |
denotes |
Figure |
T5839 |
10952-10953 |
CD |
denotes |
1 |
T5840 |
10953-10954 |
-RRB- |
denotes |
) |
T5841 |
10955-10962 |
NN |
denotes |
measure |
T5842 |
10963-10975 |
JJ |
denotes |
steady-state |
T5843 |
10976-10982 |
NN |
denotes |
levels |
T5844 |
10983-10985 |
IN |
denotes |
of |
T5845 |
10986-10988 |
JJ |
denotes |
ɛy |
T5846 |
10989-10993 |
NN |
denotes |
mRNA |
T5847 |
10993-10994 |
-COMMA- |
denotes |
, |
T5848 |
10995-10998 |
RB |
denotes |
not |
T5849 |
10999-11014 |
JJ |
denotes |
transcriptional |
T5850 |
11015-11023 |
NN |
denotes |
activity |
T5851 |
11024-11026 |
IN |
denotes |
of |
T5852 |
11027-11030 |
DT |
denotes |
the |
T5853 |
11031-11033 |
JJ |
denotes |
ɛy |
T5854 |
11034-11042 |
NN |
denotes |
promoter |
T5855 |
11044-11046 |
TO |
denotes |
To |
T5856 |
11047-11058 |
VB |
denotes |
investigate |
T5857 |
11059-11066 |
IN |
denotes |
whether |
T5858 |
11067-11071 |
NN |
denotes |
Sox6 |
T5859 |
11072-11080 |
RB |
denotes |
directly |
T5860 |
11081-11085 |
VB |
denotes |
acts |
T5861 |
11086-11088 |
IN |
denotes |
on |
T5862 |
11089-11092 |
DT |
denotes |
the |
T5863 |
11093-11095 |
JJ |
denotes |
ɛy |
T5864 |
11096-11100 |
NN |
denotes |
gene |
T5865 |
11101-11109 |
NN |
denotes |
promoter |
T5866 |
11110-11112 |
IN |
denotes |
at |
T5867 |
11113-11116 |
DT |
denotes |
the |
T5868 |
11117-11132 |
JJ |
denotes |
transcriptional |
T5869 |
11133-11138 |
NN |
denotes |
level |
T5870 |
11138-11139 |
-COMMA- |
denotes |
, |
T5871 |
11140-11142 |
PRP |
denotes |
we |
T5872 |
11143-11147 |
VB |
denotes |
used |
T5873 |
11148-11150 |
DT |
denotes |
an |
T5874 |
11151-11153 |
FW |
denotes |
in |
T5875 |
11154-11159 |
FW |
denotes |
vitro |
T5876 |
11160-11169 |
JJ |
denotes |
transient |
T5877 |
11170-11182 |
NN |
denotes |
transfection |
T5878 |
11183-11188 |
NN |
denotes |
assay |
T5879 |
11189-11192 |
CC |
denotes |
and |
T5880 |
11193-11198 |
NN |
denotes |
GM979 |
T5881 |
11199-11204 |
NN |
denotes |
cells |
T5882 |
11204-11205 |
-COMMA- |
denotes |
, |
T5883 |
11206-11207 |
DT |
denotes |
a |
T5884 |
11208-11214 |
JJ |
denotes |
murine |
T5885 |
11215-11230 |
JJ |
denotes |
erythroleukemic |
T5886 |
11231-11235 |
NN |
denotes |
cell |
T5887 |
11236-11240 |
NN |
denotes |
line |
T5888 |
11241-11245 |
WDT |
denotes |
that |
T5889 |
11246-11255 |
VB |
denotes |
expresses |
T5890 |
11256-11260 |
CC |
denotes |
both |
T5891 |
11261-11263 |
JJ |
denotes |
ɛy |
T5892 |
11264-11267 |
CC |
denotes |
and |
T5893 |
11268-11273 |
JJ |
denotes |
adult |
T5894 |
11274-11278 |
NN |
denotes |
beta |
T5895 |
11279-11286 |
NN |
denotes |
globins |
T5896 |
11287-11288 |
-LRB- |
denotes |
[ |
T5897 |
11288-11290 |
CD |
denotes |
30 |
T5898 |
11290-11291 |
-RRB- |
denotes |
] |
T5899 |
11293-11295 |
PRP |
denotes |
We |
T5900 |
11296-11305 |
VB |
denotes |
generated |
T5901 |
11306-11308 |
DT |
denotes |
an |
T5902 |
11309-11311 |
JJ |
denotes |
ɛy |
T5903 |
11312-11320 |
NN |
denotes |
promoter |
T5904 |
11321-11329 |
NN |
denotes |
reporter |
T5905 |
11330-11339 |
NN |
denotes |
construct |
T5906 |
11340-11341 |
-LRB- |
denotes |
( |
T5907 |
11341-11346 |
NN |
denotes |
E-Luc |
T5908 |
11346-11347 |
-RRB- |
denotes |
) |
T5909 |
11348-11350 |
IN |
denotes |
by |
T5910 |
11351-11357 |
VB |
denotes |
fusing |
T5911 |
11358-11359 |
DT |
denotes |
a |
T5912 |
11360-11369 |
NN |
denotes |
micro-LCR |
T5913 |
11370-11371 |
-LRB- |
denotes |
( |
T5914 |
11371-11375 |
NN |
denotes |
μLCR |
T5915 |
11375-11376 |
-RRB- |
denotes |
) |
T5916 |
11377-11384 |
NN |
denotes |
element |
T5917 |
11385-11386 |
-LRB- |
denotes |
( |
T5918 |
11386-11389 |
CD |
denotes |
2.5 |
T5919 |
11390-11392 |
NN |
denotes |
kb |
T5920 |
11392-11393 |
-RRB- |
denotes |
) |
T5921 |
11394-11395 |
-LRB- |
denotes |
[ |
T5922 |
11395-11397 |
CD |
denotes |
31 |
T5923 |
11397-11398 |
-RRB- |
denotes |
] |
T5924 |
11399-11401 |
TO |
denotes |
to |
T5925 |
11402-11405 |
DT |
denotes |
the |
T5926 |
11406-11408 |
JJ |
denotes |
ɛy |
T5927 |
11409-11417 |
JJ |
denotes |
proximal |
T5928 |
11418-11426 |
NN |
denotes |
promoter |
T5929 |
11427-11428 |
-LRB- |
denotes |
( |
T5930 |
11428-11431 |
CD |
denotes |
2.2 |
T5931 |
11432-11434 |
NN |
denotes |
kb |
T5932 |
11434-11435 |
-RRB- |
denotes |
) |
T5933 |
11435-11436 |
-COMMA- |
denotes |
, |
T5934 |
11437-11445 |
VB |
denotes |
followed |
T5935 |
11446-11448 |
IN |
denotes |
by |
T5936 |
11449-11452 |
DT |
denotes |
the |
T5937 |
11453-11463 |
NN |
denotes |
luciferase |
T5938 |
11464-11472 |
NN |
denotes |
reporter |
T5939 |
11473-11477 |
NN |
denotes |
gene |
T5940 |
11477-11478 |
-COMMA- |
denotes |
, |
T5941 |
11479-11481 |
IN |
denotes |
as |
T5942 |
11482-11487 |
VB |
denotes |
shown |
T5943 |
11488-11490 |
IN |
denotes |
in |
T5944 |
11491-11497 |
NN |
denotes |
Figure |
T5945 |
11498-11500 |
NN |
denotes |
2A |
T5946 |
11501-11502 |
-LRB- |
denotes |
( |
T5947 |
11502-11510 |
VB |
denotes |
detailed |
T5948 |
11511-11513 |
IN |
denotes |
in |
T5949 |
11514-11523 |
NNP |
denotes |
Materials |
T5950 |
11524-11527 |
CC |
denotes |
and |
T5951 |
11528-11535 |
NNP |
denotes |
Methods |
T5952 |
11535-11536 |
-RRB- |
denotes |
) |
T5953 |
11538-11552 |
NN |
denotes |
Overexpression |
T5954 |
11553-11555 |
IN |
denotes |
of |
T5955 |
11556-11560 |
NN |
denotes |
Sox6 |
T5956 |
11561-11563 |
IN |
denotes |
in |
T5957 |
11564-11569 |
NN |
denotes |
GM979 |
T5958 |
11570-11575 |
NN |
denotes |
cells |
T5959 |
11576-11578 |
IN |
denotes |
by |
T5960 |
11579-11588 |
JJ |
denotes |
transient |
T5961 |
11589-11601 |
NN |
denotes |
transfection |
T5962 |
11602-11607 |
VB |
denotes |
leads |
T5963 |
11608-11610 |
TO |
denotes |
to |
T5964 |
11611-11612 |
DT |
denotes |
a |
T5965 |
11613-11629 |
JJ |
denotes |
dosage-dependent |
T5966 |
11630-11640 |
NN |
denotes |
repression |
T5967 |
11641-11643 |
IN |
denotes |
of |
T5968 |
11644-11649 |
NN |
denotes |
E-Luc |
T5969 |
11650-11658 |
NN |
denotes |
reporter |
T5970 |
11659-11667 |
NN |
denotes |
activity |
T5971 |
11668-11669 |
-LRB- |
denotes |
( |
T5972 |
11669-11675 |
NN |
denotes |
Figure |
T5973 |
11676-11678 |
NN |
denotes |
2B |
T5974 |
11678-11679 |
-RRB- |
denotes |
) |
T5975 |
11681-11683 |
IN |
denotes |
In |
T5976 |
11684-11692 |
NN |
denotes |
contrast |
T5977 |
11692-11693 |
-COMMA- |
denotes |
, |
T5978 |
11694-11708 |
NN |
denotes |
overexpression |
T5979 |
11709-11711 |
IN |
denotes |
of |
T5980 |
11712-11713 |
DT |
denotes |
a |
T5981 |
11714-11723 |
VB |
denotes |
truncated |
T5982 |
11724-11728 |
NN |
denotes |
Sox6 |
T5983 |
11729-11736 |
NN |
denotes |
protein |
T5984 |
11737-11741 |
WDT |
denotes |
that |
T5985 |
11742-11747 |
VB |
denotes |
lacks |
T5986 |
11748-11751 |
PRP-DOLLAR- |
denotes |
its |
T5987 |
11752-11755 |
NN |
denotes |
HMG |
T5988 |
11756-11762 |
NN |
denotes |
domain |
T5989 |
11763-11764 |
-LRB- |
denotes |
[ |
T5990 |
11764-11766 |
CD |
denotes |
32 |
T5991 |
11766-11767 |
-RRB- |
denotes |
] |
T5992 |
11768-11769 |
-LRB- |
denotes |
( |
T5993 |
11769-11776 |
JJ |
denotes |
similar |
T5994 |
11777-11779 |
TO |
denotes |
to |
T5995 |
11780-11783 |
DT |
denotes |
the |
T5996 |
11784-11790 |
NN |
denotes |
p 100H |
T5997 |
11791-11796 |
NN |
denotes |
mouse |
T5998 |
11797-11803 |
NN |
denotes |
allele |
T5999 |
11803-11804 |
-RRB- |
denotes |
) |
T6000 |
11805-11810 |
VB |
denotes |
fails |
T6001 |
11811-11813 |
TO |
denotes |
to |
T6002 |
11814-11821 |
VB |
denotes |
repress |
T6003 |
11822-11827 |
NN |
denotes |
E-Luc |
T6004 |
11828-11836 |
NN |
denotes |
activity |
T6005 |
11837-11838 |
-LRB- |
denotes |
( |
T6006 |
11838-11844 |
NN |
denotes |
Figure |
T6007 |
11845-11847 |
NN |
denotes |
2B |
T6008 |
11847-11848 |
-RRB- |
denotes |
) |
T6009 |
11850-11855 |
DT |
denotes |
These |
T6010 |
11856-11860 |
NN |
denotes |
data |
T6011 |
11861-11869 |
VB |
denotes |
indicate |
T6012 |
11870-11874 |
IN |
denotes |
that |
T6013 |
11875-11879 |
NN |
denotes |
Sox6 |
T6014 |
11880-11884 |
VB |
denotes |
acts |
T6015 |
11885-11887 |
TO |
denotes |
to |
T6016 |
11888-11895 |
VB |
denotes |
repress |
T6017 |
11896-11899 |
DT |
denotes |
the |
T6018 |
11900-11902 |
JJ |
denotes |
ɛy |
T6019 |
11903-11911 |
NN |
denotes |
promoter |
T6020 |
11912-11914 |
IN |
denotes |
at |
T6021 |
11915-11918 |
DT |
denotes |
the |
T6022 |
11919-11934 |
JJ |
denotes |
transcriptional |
T6023 |
11935-11940 |
NN |
denotes |
level |
T6024 |
13323-13327 |
NN |
denotes |
Sox6 |
T6025 |
13328-13331 |
VB |
denotes |
has |
T6026 |
13332-13336 |
VB |
denotes |
been |
T6027 |
13337-13342 |
VB |
denotes |
shown |
T6028 |
13343-13345 |
TO |
denotes |
to |
T6029 |
13346-13349 |
VB |
denotes |
act |
T6030 |
13350-13352 |
IN |
denotes |
as |
T6031 |
13353-13354 |
DT |
denotes |
a |
T6032 |
13355-13364 |
NN |
denotes |
repressor |
T6033 |
13365-13368 |
CC |
denotes |
and |
T6034 |
13369-13371 |
TO |
denotes |
to |
T6035 |
13372-13380 |
VB |
denotes |
interact |
T6036 |
13381-13385 |
IN |
denotes |
with |
T6037 |
13386-13387 |
DT |
denotes |
a |
T6038 |
13388-13394 |
RB |
denotes |
widely |
T6039 |
13395-13404 |
VB |
denotes |
expressed |
T6040 |
13405-13417 |
NN |
denotes |
co-repressor |
T6041 |
13417-13418 |
-COMMA- |
denotes |
, |
T6042 |
13419-13424 |
NN |
denotes |
CtBP2 |
T6043 |
13424-13425 |
-COMMA- |
denotes |
, |
T6044 |
13426-13428 |
IN |
denotes |
on |
T6045 |
13429-13432 |
DT |
denotes |
the |
T6046 |
13433-13438 |
NN |
denotes |
fgf-3 |
T6047 |
13439-13447 |
NN |
denotes |
promoter |
T6048 |
13448-13449 |
-LRB- |
denotes |
[ |
T6049 |
13449-13450 |
CD |
denotes |
5 |
T6050 |
13450-13451 |
-RRB- |
denotes |
] |
T6051 |
13453-13458 |
NN |
denotes |
CtBP2 |
T6052 |
13459-13461 |
VB |
denotes |
is |
T6053 |
13462-13471 |
VB |
denotes |
expressed |
T6054 |
13472-13474 |
IN |
denotes |
in |
T6055 |
13475-13480 |
NN |
denotes |
GM979 |
T6056 |
13481-13486 |
NN |
denotes |
cells |
T6057 |
13487-13488 |
-LRB- |
denotes |
( |
T6058 |
13488-13499 |
JJ |
denotes |
unpublished |
T6059 |
13500-13504 |
NN |
denotes |
data |
T6060 |
13504-13505 |
-RRB- |
denotes |
) |
T6061 |
13507-13509 |
TO |
denotes |
To |
T6062 |
13510-13521 |
VB |
denotes |
investigate |
T6063 |
13522-13529 |
IN |
denotes |
whether |
T6064 |
13530-13533 |
DT |
denotes |
the |
T6065 |
13534-13545 |
NN |
denotes |
interaction |
T6066 |
13546-13550 |
IN |
denotes |
with |
T6067 |
13551-13556 |
NN |
denotes |
CtBP2 |
T6068 |
13557-13559 |
VB |
denotes |
is |
T6069 |
13560-13568 |
VB |
denotes |
required |
T6070 |
13569-13572 |
IN |
denotes |
for |
T6071 |
13573-13577 |
NN |
denotes |
Sox6 |
T6072 |
13578-13588 |
NN |
denotes |
repression |
T6073 |
13589-13591 |
IN |
denotes |
of |
T6074 |
13592-13595 |
DT |
denotes |
the |
T6075 |
13596-13598 |
JJ |
denotes |
ɛy |
T6076 |
13599-13607 |
NN |
denotes |
promoter |
T6077 |
13607-13608 |
-COMMA- |
denotes |
, |
T6078 |
13609-13611 |
PRP |
denotes |
we |
T6079 |
13612-13622 |
VB |
denotes |
introduced |
T6080 |
13623-13624 |
DT |
denotes |
a |
T6081 |
13625-13630 |
NN |
denotes |
point |
T6082 |
13631-13639 |
NN |
denotes |
mutation |
T6083 |
13640-13641 |
-LRB- |
denotes |
( |
T6084 |
13641-13646 |
NN |
denotes |
L386H |
T6085 |
13646-13647 |
-RRB- |
denotes |
) |
T6086 |
13648-13650 |
IN |
denotes |
in |
T6087 |
13651-13654 |
DT |
denotes |
the |
T6088 |
13655-13659 |
NN |
denotes |
Sox6 |
T6089 |
13660-13667 |
NN |
denotes |
protein |
T6090 |
13668-13672 |
WDT |
denotes |
that |
T6091 |
13673-13676 |
VB |
denotes |
has |
T6092 |
13677-13681 |
VB |
denotes |
been |
T6093 |
13682-13692 |
RB |
denotes |
previously |
T6094 |
13693-13701 |
VB |
denotes |
reported |
T6095 |
13702-13704 |
TO |
denotes |
to |
T6096 |
13705-13707 |
VB |
denotes |
be |
T6097 |
13708-13718 |
JJ |
denotes |
sufficient |
T6098 |
13719-13721 |
TO |
denotes |
to |
T6099 |
13722-13729 |
VB |
denotes |
abolish |
T6100 |
13730-13740 |
JJ |
denotes |
Sox6-CtBP2 |
T6101 |
13741-13752 |
NN |
denotes |
interaction |
T6102 |
13753-13754 |
-LRB- |
denotes |
[ |
T6103 |
13754-13755 |
CD |
denotes |
5 |
T6104 |
13755-13756 |
-RRB- |
denotes |
] |
T6105 |
13758-13762 |
DT |
denotes |
This |
T6106 |
13763-13768 |
JJ |
denotes |
amino |
T6107 |
13769-13773 |
NN |
denotes |
acid |
T6108 |
13774-13780 |
NN |
denotes |
change |
T6109 |
13781-13783 |
VB |
denotes |
is |
T6110 |
13784-13787 |
RB |
denotes |
not |
T6111 |
13788-13790 |
IN |
denotes |
in |
T6112 |
13791-13794 |
DT |
denotes |
the |
T6113 |
13795-13798 |
NN |
denotes |
HMG |
T6114 |
13799-13802 |
NN |
denotes |
DNA |
T6115 |
13803-13810 |
NN |
denotes |
binding |
T6116 |
13811-13817 |
NN |
denotes |
domain |
T6117 |
13819-13826 |
RB |
denotes |
However |
T6118 |
13826-13827 |
-COMMA- |
denotes |
, |
T6119 |
13828-13832 |
DT |
denotes |
this |
T6120 |
13833-13839 |
JJ |
denotes |
mutant |
T6121 |
13840-13847 |
NN |
denotes |
version |
T6122 |
13848-13850 |
IN |
denotes |
of |
T6123 |
13851-13855 |
NN |
denotes |
Sox6 |
T6124 |
13856-13863 |
VB |
denotes |
retains |
T6125 |
13864-13867 |
DT |
denotes |
the |
T6126 |
13868-13875 |
NN |
denotes |
ability |
T6127 |
13876-13878 |
TO |
denotes |
to |
T6128 |
13879-13886 |
VB |
denotes |
repress |
T6129 |
13887-13890 |
DT |
denotes |
the |
T6130 |
13891-13893 |
JJ |
denotes |
ɛy |
T6131 |
13894-13902 |
NN |
denotes |
promoter |
T6132 |
13903-13905 |
IN |
denotes |
in |
T6133 |
13906-13909 |
DT |
denotes |
the |
T6134 |
13910-13922 |
NN |
denotes |
transfection |
T6135 |
13923-13928 |
NN |
denotes |
assay |
T6136 |
13929-13930 |
-LRB- |
denotes |
( |
T6137 |
13930-13936 |
NN |
denotes |
Figure |
T6138 |
13937-13939 |
NN |
denotes |
2B |
T6139 |
13939-13940 |
-RRB- |
denotes |
) |
T6140 |
13940-13941 |
-COMMA- |
denotes |
, |
T6141 |
13942-13952 |
VB |
denotes |
indicating |
T6142 |
13953-13957 |
IN |
denotes |
that |
T6143 |
13958-13962 |
NN |
denotes |
Sox6 |
T6144 |
13963-13972 |
VB |
denotes |
represses |
T6145 |
13973-13976 |
DT |
denotes |
the |
T6146 |
13977-13979 |
JJ |
denotes |
ɛy |
T6147 |
13980-13988 |
NN |
denotes |
promoter |
T6148 |
13989-13991 |
IN |
denotes |
in |
T6149 |
13992-13993 |
DT |
denotes |
a |
T6150 |
13994-14011 |
JJ |
denotes |
CtBP2-independent |
T6151 |
14012-14018 |
NN |
denotes |
manner |
T6152 |
14020-14028 |
NN |
denotes |
Deletion |
T6153 |
14029-14037 |
NN |
denotes |
analysis |
T6154 |
14038-14040 |
IN |
denotes |
of |
T6155 |
14041-14044 |
DT |
denotes |
the |
T6156 |
14045-14047 |
JJ |
denotes |
ɛy |
T6157 |
14048-14056 |
NN |
denotes |
promoter |
T6158 |
14056-14057 |
-COMMA- |
denotes |
, |
T6159 |
14058-14060 |
IN |
denotes |
as |
T6160 |
14061-14066 |
VB |
denotes |
shown |
T6161 |
14067-14069 |
IN |
denotes |
in |
T6162 |
14070-14076 |
NN |
denotes |
Figure |
T6163 |
14077-14079 |
NN |
denotes |
2C |
T6164 |
14079-14080 |
-COMMA- |
denotes |
, |
T6165 |
14081-14088 |
VB |
denotes |
defined |
T6166 |
14089-14090 |
DT |
denotes |
a |
T6167 |
14091-14097 |
NN |
denotes |
region |
T6168 |
14098-14099 |
-LRB- |
denotes |
( |
T6169 |
14099-14102 |
CD |
denotes |
−63 |
T6170 |
14103-14105 |
TO |
denotes |
to |
T6171 |
14106-14109 |
CD |
denotes |
−37 |
T6172 |
14109-14110 |
-RRB- |
denotes |
) |
T6173 |
14111-14117 |
IN |
denotes |
within |
T6174 |
14118-14121 |
DT |
denotes |
the |
T6175 |
14122-14124 |
JJ |
denotes |
ɛy |
T6176 |
14125-14133 |
JJ |
denotes |
proximal |
T6177 |
14134-14142 |
NN |
denotes |
promoter |
T6178 |
14143-14147 |
WDT |
denotes |
that |
T6179 |
14148-14150 |
VB |
denotes |
is |
T6180 |
14151-14159 |
JJ |
denotes |
critical |
T6181 |
14160-14163 |
IN |
denotes |
for |
T6182 |
14164-14168 |
NN |
denotes |
Sox6 |
T6183 |
14169-14179 |
NN |
denotes |
repression |
T6184 |
14181-14189 |
NN |
denotes |
Analysis |
T6185 |
14190-14192 |
IN |
denotes |
of |
T6186 |
14193-14197 |
DT |
denotes |
this |
T6187 |
14198-14203 |
JJ |
denotes |
short |
T6188 |
14204-14210 |
NN |
denotes |
region |
T6189 |
14211-14218 |
VB |
denotes |
reveals |
T6190 |
14219-14222 |
CD |
denotes |
two |
T6191 |
14223-14231 |
NN |
denotes |
Sox/Sox6 |
T6192 |
14232-14241 |
NN |
denotes |
consensus |
T6193 |
14242-14249 |
NN |
denotes |
binding |
T6194 |
14250-14255 |
NN |
denotes |
sites |
T6195 |
14256-14257 |
-LRB- |
denotes |
[ |
T6196 |
14257-14258 |
CD |
denotes |
5 |
T6197 |
14258-14259 |
-RRB- |
denotes |
] |
T6198 |
14260-14261 |
-LRB- |
denotes |
( |
T6199 |
14261-14267 |
NN |
denotes |
Figure |
T6200 |
14268-14270 |
NN |
denotes |
3A |
T6201 |
14270-14271 |
-RRB- |
denotes |
) |
T7433 |
16841-16845 |
NN |
denotes |
EMSA |
T7434 |
16846-16849 |
CC |
denotes |
and |
T7435 |
16850-16854 |
NNP |
denotes |
ChIP |
T7436 |
16855-16861 |
NNP |
denotes |
Assays |
T7437 |
16862-16866 |
NNP |
denotes |
Show |
T7438 |
16867-16871 |
IN |
denotes |
that |
T7439 |
16872-16876 |
NN |
denotes |
Sox6 |
T7440 |
16877-16885 |
RB |
denotes |
Directly |
T7441 |
16886-16891 |
VB |
denotes |
Binds |
T7442 |
16892-16894 |
TO |
denotes |
to |
T7443 |
16895-16898 |
DT |
denotes |
the |
T7444 |
16899-16901 |
JJ |
denotes |
ɛy |
T7445 |
16902-16910 |
NN |
denotes |
Promoter |
T7446 |
16911-16915 |
NN |
denotes |
Sox6 |
T7447 |
16916-16921 |
MD |
denotes |
might |
T7448 |
16922-16929 |
VB |
denotes |
repress |
T7449 |
16930-16933 |
DT |
denotes |
the |
T7450 |
16934-16936 |
JJ |
denotes |
ɛy |
T7451 |
16937-16945 |
NN |
denotes |
promoter |
T7452 |
16945-16946 |
-COMMA- |
denotes |
, |
T7453 |
16947-16953 |
CC |
denotes |
either |
T7454 |
16954-16961 |
IN |
denotes |
through |
T7455 |
16962-16968 |
JJ |
denotes |
direct |
T7456 |
16969-16977 |
JJ |
denotes |
physical |
T7457 |
16978-16985 |
NN |
denotes |
contact |
T7458 |
16986-16990 |
IN |
denotes |
with |
T7459 |
16991-16994 |
DT |
denotes |
the |
T7460 |
16995-17003 |
NN |
denotes |
promoter |
T7461 |
17004-17006 |
CC |
denotes |
or |
T7462 |
17007-17009 |
IN |
denotes |
by |
T7463 |
17010-17020 |
VB |
denotes |
regulating |
T7464 |
17021-17034 |
NN |
denotes |
intermediates |
T7465 |
17035-17044 |
VB |
denotes |
affecting |
T7466 |
17045-17048 |
DT |
denotes |
the |
T7467 |
17049-17051 |
JJ |
denotes |
ɛy |
T7468 |
17052-17060 |
NN |
denotes |
promoter |
T7469 |
17062-17064 |
TO |
denotes |
To |
T7470 |
17065-17076 |
VB |
denotes |
investigate |
T7471 |
17077-17084 |
IN |
denotes |
whether |
T7472 |
17085-17089 |
NN |
denotes |
Sox6 |
T7473 |
17090-17092 |
VB |
denotes |
is |
T7474 |
17093-17101 |
RB |
denotes |
directly |
T7475 |
17102-17112 |
VB |
denotes |
associated |
T7476 |
17113-17117 |
IN |
denotes |
with |
T7477 |
17118-17121 |
DT |
denotes |
the |
T7478 |
17122-17124 |
JJ |
denotes |
ɛy |
T7479 |
17125-17133 |
NN |
denotes |
promoter |
T7480 |
17133-17134 |
-COMMA- |
denotes |
, |
T7481 |
17135-17137 |
PRP |
denotes |
we |
T7482 |
17138-17143 |
RB |
denotes |
first |
T7483 |
17144-17153 |
VB |
denotes |
performed |
T7484 |
17154-17169 |
JJ |
denotes |
electrophoretic |
T7485 |
17170-17178 |
NN |
denotes |
mobility |
T7486 |
17179-17184 |
NN |
denotes |
shift |
T7487 |
17185-17191 |
NN |
denotes |
assays |
T7488 |
17192-17193 |
-LRB- |
denotes |
( |
T7489 |
17193-17197 |
NN |
denotes |
EMSA |
T7490 |
17197-17198 |
-RRB- |
denotes |
) |
T7491 |
17199-17204 |
VB |
denotes |
using |
T7492 |
17205-17206 |
DT |
denotes |
a |
T7493 |
17207-17219 |
JJ |
denotes |
c-Myc-tagged |
T7494 |
17220-17224 |
NN |
denotes |
Sox6 |
T7495 |
17225-17227 |
IN |
denotes |
in |
T7496 |
17228-17229 |
DT |
denotes |
a |
T7497 |
17230-17242 |
NN |
denotes |
reticulocyte |
T7498 |
17243-17255 |
JJ |
denotes |
lysate-based |
T7499 |
17256-17281 |
NN |
denotes |
transcription/translation |
T7500 |
17282-17284 |
FW |
denotes |
in |
T7501 |
17285-17290 |
FW |
denotes |
vitro |
T7502 |
17291-17297 |
NN |
denotes |
system |
T7503 |
17299-17302 |
DT |
denotes |
The |
T7504 |
17303-17309 |
NN |
denotes |
probes |
T7505 |
17310-17314 |
VB |
denotes |
used |
T7506 |
17315-17318 |
VB |
denotes |
are |
T7507 |
17319-17325 |
VB |
denotes |
listed |
T7508 |
17326-17328 |
IN |
denotes |
in |
T7509 |
17329-17335 |
NN |
denotes |
Figure |
T7510 |
17336-17338 |
NN |
denotes |
3A |
T7511 |
17340-17343 |
DT |
denotes |
The |
T7512 |
17344-17351 |
NN |
denotes |
36–base |
T7513 |
17352-17356 |
NN |
denotes |
pair |
T7514 |
17357-17358 |
-LRB- |
denotes |
( |
T7515 |
17358-17360 |
NN |
denotes |
bp |
T7516 |
17360-17361 |
-RRB- |
denotes |
) |
T7517 |
17362-17364 |
NN |
denotes |
WT |
T7518 |
17365-17370 |
NN |
denotes |
probe |
T7519 |
17371-17382 |
VB |
denotes |
corresponds |
T7520 |
17383-17385 |
TO |
denotes |
to |
T7521 |
17386-17389 |
DT |
denotes |
the |
T7522 |
17390-17398 |
JJ |
denotes |
critical |
T7523 |
17399-17405 |
NN |
denotes |
region |
T7524 |
17406-17408 |
IN |
denotes |
of |
T7525 |
17409-17412 |
DT |
denotes |
the |
T7526 |
17413-17415 |
JJ |
denotes |
ɛy |
T7527 |
17416-17424 |
NN |
denotes |
promoter |
T7528 |
17425-17432 |
VB |
denotes |
defined |
T7529 |
17433-17435 |
IN |
denotes |
in |
T7530 |
17436-17439 |
PRP-DOLLAR- |
denotes |
our |
T7531 |
17440-17448 |
NN |
denotes |
promoter |
T7532 |
17449-17457 |
NN |
denotes |
deletion |
T7533 |
17458-17466 |
NN |
denotes |
analyses |
T7534 |
17468-17472 |
DT |
denotes |
This |
T7535 |
17473-17478 |
NN |
denotes |
probe |
T7536 |
17479-17487 |
VB |
denotes |
contains |
T7537 |
17488-17491 |
CD |
denotes |
two |
T7538 |
17492-17501 |
NN |
denotes |
consensus |
T7539 |
17502-17510 |
NN |
denotes |
Sox/Sox6 |
T7540 |
17511-17518 |
NN |
denotes |
binding |
T7541 |
17519-17524 |
NN |
denotes |
sites |
T7542 |
17526-17530 |
RB |
denotes |
Also |
T7543 |
17531-17539 |
VB |
denotes |
included |
T7544 |
17540-17542 |
IN |
denotes |
in |
T7545 |
17543-17546 |
PRP-DOLLAR- |
denotes |
our |
T7546 |
17547-17551 |
NN |
denotes |
EMSA |
T7547 |
17552-17555 |
VB |
denotes |
are |
T7548 |
17556-17561 |
CD |
denotes |
three |
T7549 |
17562-17569 |
VB |
denotes |
mutated |
T7550 |
17570-17576 |
NN |
denotes |
probes |
T7551 |
17577-17581 |
WDT |
denotes |
that |
T7552 |
17582-17585 |
VB |
denotes |
are |
T7553 |
17585-17586 |
-COMMA- |
denotes |
, |
T7554 |
17587-17593 |
CC |
denotes |
either |
T7555 |
17594-17603 |
VB |
denotes |
truncated |
T7556 |
17604-17605 |
-LRB- |
denotes |
( |
T7557 |
17605-17607 |
NN |
denotes |
M1 |
T7558 |
17607-17608 |
-RRB- |
denotes |
) |
T7559 |
17608-17609 |
-COMMA- |
denotes |
, |
T7560 |
17610-17612 |
CC |
denotes |
or |
T7561 |
17613-17620 |
VB |
denotes |
mutated |
T7562 |
17621-17622 |
-LRB- |
denotes |
( |
T7563 |
17622-17624 |
NN |
denotes |
M2 |
T7564 |
17625-17628 |
CC |
denotes |
and |
T7565 |
17629-17631 |
NN |
denotes |
M3 |
T7566 |
17631-17632 |
-RRB- |
denotes |
) |
T7567 |
17633-17635 |
IN |
denotes |
in |
T7568 |
17636-17644 |
NN |
denotes |
Sox/Sox6 |
T7569 |
17645-17652 |
NN |
denotes |
binding |
T7570 |
17653-17658 |
NN |
denotes |
sites |
T7571 |
17659-17660 |
-LRB- |
denotes |
( |
T7572 |
17660-17666 |
NN |
denotes |
Figure |
T7573 |
17667-17669 |
NN |
denotes |
3A |
T7574 |
17669-17670 |
-RRB- |
denotes |
) |
T7575 |
17672-17676 |
NN |
denotes |
Sox6 |
T7576 |
17677-17679 |
VB |
denotes |
is |
T7577 |
17680-17684 |
JJ |
denotes |
able |
T7578 |
17685-17687 |
TO |
denotes |
to |
T7579 |
17688-17698 |
RB |
denotes |
physically |
T7580 |
17699-17708 |
VB |
denotes |
associate |
T7581 |
17709-17713 |
IN |
denotes |
with |
T7582 |
17714-17717 |
DT |
denotes |
the |
T7583 |
17718-17723 |
JJ |
denotes |
36-bp |
T7584 |
17724-17730 |
NN |
denotes |
region |
T7585 |
17731-17732 |
-LRB- |
denotes |
( |
T7586 |
17732-17738 |
NN |
denotes |
Figure |
T7587 |
17739-17741 |
NN |
denotes |
3B |
T7588 |
17741-17742 |
-RRB- |
denotes |
) |
T7589 |
17743-17749 |
IN |
denotes |
within |
T7590 |
17750-17753 |
DT |
denotes |
the |
T7591 |
17754-17756 |
JJ |
denotes |
ɛy |
T7592 |
17757-17765 |
NN |
denotes |
promoter |
T7593 |
17766-17773 |
VB |
denotes |
defined |
T7594 |
17774-17776 |
IN |
denotes |
by |
T7595 |
17777-17780 |
DT |
denotes |
the |
T7596 |
17781-17789 |
NN |
denotes |
deletion |
T7597 |
17790-17798 |
NN |
denotes |
analysis |
T7598 |
17799-17810 |
NN |
denotes |
experiments |
T7599 |
17811-17812 |
-LRB- |
denotes |
( |
T7600 |
17812-17818 |
NN |
denotes |
Figure |
T7601 |
17819-17821 |
NN |
denotes |
2C |
T7602 |
17821-17822 |
-RRB- |
denotes |
) |
T7603 |
17824-17827 |
DT |
denotes |
The |
T7604 |
17828-17833 |
JJ |
denotes |
36-bp |
T7605 |
17834-17839 |
NN |
denotes |
probe |
T7606 |
17840-17843 |
VB |
denotes |
was |
T7607 |
17844-17851 |
VB |
denotes |
shifted |
T7608 |
17852-17854 |
IN |
denotes |
by |
T7609 |
17855-17858 |
DT |
denotes |
the |
T7610 |
17859-17865 |
VB |
denotes |
tagged |
T7611 |
17866-17870 |
NN |
denotes |
Sox6 |
T7612 |
17871-17878 |
NN |
denotes |
protein |
T7613 |
17880-17888 |
RB |
denotes |
Moreover |
T7614 |
17888-17889 |
-COMMA- |
denotes |
, |
T7615 |
17890-17894 |
CC |
denotes |
both |
T7616 |
17895-17900 |
NN |
denotes |
c-Myc |
T7617 |
17901-17904 |
CC |
denotes |
and |
T7618 |
17905-17909 |
NN |
denotes |
Sox6 |
T7619 |
17910-17920 |
NN |
denotes |
antibodies |
T7620 |
17921-17931 |
VB |
denotes |
supershift |
T7621 |
17932-17935 |
DT |
denotes |
the |
T7622 |
17936-17940 |
NN |
denotes |
band |
T7623 |
17940-17941 |
-COMMA- |
denotes |
, |
T7624 |
17942-17952 |
VB |
denotes |
indicating |
T7625 |
17953-17957 |
IN |
denotes |
that |
T7626 |
17958-17961 |
DT |
denotes |
the |
T7627 |
17962-17969 |
NN |
denotes |
binding |
T7628 |
17970-17972 |
VB |
denotes |
is |
T7629 |
17973-17986 |
JJ |
denotes |
Sox6-specific |
T7630 |
17988-17990 |
TO |
denotes |
To |
T7631 |
17991-17995 |
VB |
denotes |
rule |
T7632 |
17996-17999 |
RP |
denotes |
out |
T7633 |
18000-18003 |
DT |
denotes |
the |
T7634 |
18004-18015 |
NN |
denotes |
possibility |
T7635 |
18016-18020 |
IN |
denotes |
that |
T7636 |
18021-18024 |
DT |
denotes |
the |
T7637 |
18025-18030 |
NN |
denotes |
c-Myc |
T7638 |
18031-18034 |
NN |
denotes |
tag |
T7639 |
18035-18041 |
PRP |
denotes |
itself |
T7640 |
18042-18047 |
VB |
denotes |
binds |
T7641 |
18048-18050 |
TO |
denotes |
to |
T7642 |
18051-18054 |
DT |
denotes |
the |
T7643 |
18055-18060 |
NN |
denotes |
probe |
T7644 |
18060-18061 |
-COMMA- |
denotes |
, |
T7645 |
18062-18064 |
DT |
denotes |
an |
T7646 |
18065-18074 |
JJ |
denotes |
HA-tagged |
T7647 |
18075-18079 |
NN |
denotes |
Sox6 |
T7648 |
18080-18083 |
VB |
denotes |
was |
T7649 |
18084-18088 |
VB |
denotes |
used |
T7650 |
18089-18091 |
IN |
denotes |
in |
T7651 |
18092-18099 |
DT |
denotes |
another |
T7652 |
18100-18104 |
NN |
denotes |
EMSA |
T7653 |
18105-18109 |
WDT |
denotes |
that |
T7654 |
18110-18119 |
VB |
denotes |
confirmed |
T7655 |
18120-18125 |
DT |
denotes |
these |
T7656 |
18126-18133 |
NN |
denotes |
results |
T7657 |
18134-18135 |
-LRB- |
denotes |
( |
T7658 |
18135-18141 |
NN |
denotes |
Figure |
T7659 |
18142-18144 |
NN |
denotes |
3C |
T7660 |
18144-18145 |
-RRB- |
denotes |
) |
T7661 |
18147-18151 |
RB |
denotes |
Next |
T7662 |
18151-18152 |
-COMMA- |
denotes |
, |
T7663 |
18153-18160 |
JJ |
denotes |
nuclear |
T7664 |
18161-18169 |
NN |
denotes |
extracts |
T7665 |
18170-18174 |
IN |
denotes |
from |
T7666 |
18175-18178 |
NN |
denotes |
MEL |
T7667 |
18179-18184 |
NN |
denotes |
cells |
T7668 |
18185-18189 |
VB |
denotes |
were |
T7669 |
18190-18194 |
VB |
denotes |
used |
T7670 |
18195-18197 |
IN |
denotes |
in |
T7671 |
18198-18202 |
NN |
denotes |
EMSA |
T7672 |
18203-18212 |
VB |
denotes |
employing |
T7673 |
18213-18216 |
DT |
denotes |
the |
T7674 |
18217-18221 |
JJ |
denotes |
same |
T7675 |
18222-18227 |
JJ |
denotes |
36-bp |
T7676 |
18228-18233 |
NN |
denotes |
probe |
T7677 |
18235-18238 |
NN |
denotes |
MEL |
T7678 |
18239-18244 |
NN |
denotes |
cells |
T7679 |
18244-18245 |
-COMMA- |
denotes |
, |
T7680 |
18246-18247 |
DT |
denotes |
a |
T7681 |
18248-18254 |
JJ |
denotes |
murine |
T7682 |
18255-18270 |
JJ |
denotes |
erythroleukemic |
T7683 |
18271-18275 |
NN |
denotes |
cell |
T7684 |
18276-18280 |
NN |
denotes |
line |
T7685 |
18280-18281 |
-COMMA- |
denotes |
, |
T7686 |
18282-18289 |
VB |
denotes |
express |
T7687 |
18290-18295 |
JJ |
denotes |
adult |
T7688 |
18296-18297 |
NN |
denotes |
β |
T7689 |
18298-18305 |
NN |
denotes |
globins |
T7690 |
18305-18306 |
-COMMA- |
denotes |
, |
T7691 |
18307-18310 |
CC |
denotes |
but |
T7692 |
18311-18314 |
RB |
denotes |
not |
T7693 |
18315-18317 |
VB |
denotes |
ɛy |
T7694 |
18318-18319 |
-LRB- |
denotes |
[ |
T7695 |
18319-18321 |
CD |
denotes |
33 |
T7696 |
18321-18322 |
-RRB- |
denotes |
] |
T7697 |
18324-18328 |
NN |
denotes |
Sox6 |
T7698 |
18329-18337 |
RB |
denotes |
directly |
T7699 |
18338-18343 |
VB |
denotes |
binds |
T7700 |
18344-18346 |
TO |
denotes |
to |
T7701 |
18347-18351 |
DT |
denotes |
this |
T7702 |
18352-18355 |
NN |
denotes |
DNA |
T7703 |
18356-18364 |
NN |
denotes |
sequence |
T7704 |
18365-18367 |
IN |
denotes |
in |
T7705 |
18368-18371 |
NN |
denotes |
MEL |
T7706 |
18372-18377 |
NN |
denotes |
cells |
T7707 |
18378-18379 |
-LRB- |
denotes |
( |
T7708 |
18379-18385 |
NN |
denotes |
Figure |
T7709 |
18386-18388 |
NN |
denotes |
3D |
T7710 |
18388-18389 |
-RRB- |
denotes |
) |
T7711 |
18391-18394 |
DT |
denotes |
The |
T7712 |
18395-18401 |
JJ |
denotes |
intact |
T7713 |
18402-18411 |
NN |
denotes |
consensus |
T7714 |
18412-18420 |
NN |
denotes |
Sox/Sox6 |
T7715 |
18421-18428 |
NN |
denotes |
binding |
T7716 |
18429-18434 |
NN |
denotes |
sites |
T7717 |
18435-18437 |
IN |
denotes |
of |
T7718 |
18438-18441 |
DT |
denotes |
the |
T7719 |
18442-18445 |
NN |
denotes |
DNA |
T7720 |
18446-18451 |
NN |
denotes |
probe |
T7721 |
18452-18455 |
VB |
denotes |
are |
T7722 |
18456-18464 |
VB |
denotes |
required |
T7723 |
18465-18468 |
IN |
denotes |
for |
T7724 |
18469-18472 |
DT |
denotes |
the |
T7725 |
18473-18480 |
NN |
denotes |
binding |
T7726 |
18480-18481 |
-COMMA- |
denotes |
, |
T7727 |
18482-18484 |
IN |
denotes |
as |
T7728 |
18485-18490 |
VB |
denotes |
shown |
T7729 |
18491-18493 |
IN |
denotes |
in |
T7730 |
18494-18497 |
DT |
denotes |
the |
T7731 |
18498-18509 |
NN |
denotes |
competition |
T7732 |
18510-18515 |
NN |
denotes |
assay |
T7733 |
18516-18517 |
-LRB- |
denotes |
( |
T7734 |
18517-18523 |
NN |
denotes |
Figure |
T7735 |
18524-18526 |
NN |
denotes |
3E |
T7736 |
18526-18527 |
-RRB- |
denotes |
) |
T7737 |
18529-18537 |
NN |
denotes |
Ablation |
T7738 |
18538-18540 |
IN |
denotes |
of |
T7739 |
18541-18549 |
JJ |
denotes |
putative |
T7740 |
18550-18558 |
NN |
denotes |
Sox/Sox6 |
T7741 |
18559-18566 |
NN |
denotes |
binding |
T7742 |
18567-18572 |
NN |
denotes |
sites |
T7743 |
18573-18574 |
-LRB- |
denotes |
( |
T7744 |
18574-18576 |
NN |
denotes |
M1 |
T7745 |
18577-18580 |
CC |
denotes |
and |
T7746 |
18581-18583 |
NN |
denotes |
M3 |
T7747 |
18583-18584 |
-RRB- |
denotes |
) |
T7748 |
18585-18592 |
VB |
denotes |
abolish |
T7749 |
18593-18598 |
PRP-DOLLAR- |
denotes |
their |
T7750 |
18599-18606 |
NN |
denotes |
ability |
T7751 |
18607-18609 |
TO |
denotes |
to |
T7752 |
18610-18617 |
VB |
denotes |
compete |
T7753 |
18618-18620 |
IN |
denotes |
in |
T7754 |
18621-18625 |
NN |
denotes |
EMSA |
T7755 |
18626-18627 |
-LRB- |
denotes |
( |
T7756 |
18627-18633 |
NN |
denotes |
Figure |
T7757 |
18634-18636 |
NN |
denotes |
3E |
T7758 |
18636-18637 |
-RRB- |
denotes |
) |
T7759 |
18639-18642 |
DT |
denotes |
The |
T7760 |
18643-18645 |
NN |
denotes |
M2 |
T7761 |
18646-18652 |
JJ |
denotes |
mutant |
T7762 |
18653-18658 |
NN |
denotes |
probe |
T7763 |
18659-18662 |
MD |
denotes |
may |
T7764 |
18663-18670 |
VB |
denotes |
compete |
T7765 |
18671-18680 |
RB |
denotes |
partially |
T7766 |
18681-18685 |
IN |
denotes |
with |
T7767 |
18686-18688 |
NN |
denotes |
WT |
T7768 |
18689-18696 |
NN |
denotes |
binding |
T7769 |
18698-18700 |
TO |
denotes |
To |
T7770 |
18701-18712 |
VB |
denotes |
investigate |
T7771 |
18713-18716 |
DT |
denotes |
the |
T7772 |
18717-18727 |
JJ |
denotes |
functional |
T7773 |
18728-18740 |
NN |
denotes |
significance |
T7774 |
18741-18743 |
IN |
denotes |
of |
T7775 |
18744-18747 |
DT |
denotes |
the |
T7776 |
18748-18754 |
JJ |
denotes |
intact |
T7777 |
18755-18763 |
NN |
denotes |
Sox/Sox6 |
T7778 |
18764-18771 |
NN |
denotes |
binding |
T7779 |
18772-18777 |
NN |
denotes |
sites |
T7780 |
18777-18778 |
-COMMA- |
denotes |
, |
T7781 |
18779-18782 |
DT |
denotes |
the |
T7782 |
18783-18785 |
JJ |
denotes |
ɛy |
T7783 |
18786-18794 |
NN |
denotes |
promoter |
T7784 |
18795-18803 |
NN |
denotes |
reporter |
T7785 |
18804-18814 |
NN |
denotes |
constructs |
T7786 |
18815-18819 |
IN |
denotes |
with |
T7787 |
18820-18831 |
VB |
denotes |
mutagenized |
T7788 |
18832-18840 |
NN |
denotes |
Sox/Sox6 |
T7789 |
18841-18848 |
NN |
denotes |
binding |
T7790 |
18849-18854 |
NN |
denotes |
sites |
T7791 |
18855-18859 |
VB |
denotes |
were |
T7792 |
18860-18874 |
VB |
denotes |
co-transfected |
T7793 |
18875-18879 |
IN |
denotes |
with |
T7794 |
18880-18883 |
DT |
denotes |
the |
T7795 |
18884-18888 |
NN |
denotes |
Sox6 |
T7796 |
18889-18903 |
NN |
denotes |
overexpression |
T7797 |
18904-18910 |
NN |
denotes |
vector |
T7798 |
18911-18915 |
IN |
denotes |
into |
T7799 |
18916-18921 |
NN |
denotes |
GM979 |
T7800 |
18922-18927 |
NN |
denotes |
cells |
T7801 |
18929-18939 |
JJ |
denotes |
Consistent |
T7802 |
18940-18944 |
IN |
denotes |
with |
T7803 |
18945-18948 |
DT |
denotes |
the |
T7804 |
18949-18953 |
NN |
denotes |
EMSA |
T7805 |
18954-18961 |
NN |
denotes |
results |
T7806 |
18961-18962 |
-COMMA- |
denotes |
, |
T7807 |
18963-18966 |
DT |
denotes |
the |
T7808 |
18967-18973 |
JJ |
denotes |
mutant |
T7809 |
18974-18976 |
JJ |
denotes |
ɛy |
T7810 |
18977-18985 |
NN |
denotes |
promoter |
T7811 |
18986-18994 |
NN |
denotes |
reporter |
T7812 |
18995-19005 |
NN |
denotes |
constructs |
T7813 |
19006-19007 |
-LRB- |
denotes |
( |
T7814 |
19007-19011 |
IN |
denotes |
with |
T7815 |
19012-19018 |
CC |
denotes |
either |
T7816 |
19019-19022 |
CD |
denotes |
one |
T7817 |
19023-19025 |
CC |
denotes |
or |
T7818 |
19026-19030 |
CC |
denotes |
both |
T7819 |
19031-19039 |
NN |
denotes |
Sox/Sox6 |
T7820 |
19040-19047 |
NN |
denotes |
binding |
T7821 |
19048-19053 |
NN |
denotes |
sites |
T7822 |
19054-19065 |
VB |
denotes |
mutagenized |
T7823 |
19065-19066 |
-RRB- |
denotes |
) |
T7824 |
19067-19069 |
VB |
denotes |
do |
T7825 |
19070-19073 |
RB |
denotes |
not |
T7826 |
19074-19080 |
VB |
denotes |
result |
T7827 |
19081-19083 |
IN |
denotes |
in |
T7828 |
19084-19095 |
JJ |
denotes |
significant |
T7829 |
19096-19104 |
NN |
denotes |
promoter |
T7830 |
19105-19115 |
NN |
denotes |
repression |
T7831 |
19116-19118 |
IN |
denotes |
in |
T7832 |
19119-19131 |
NN |
denotes |
transfection |
T7833 |
19132-19139 |
NN |
denotes |
studies |
T7834 |
19140-19141 |
-LRB- |
denotes |
( |
T7835 |
19141-19147 |
NN |
denotes |
Figure |
T7836 |
19148-19150 |
NN |
denotes |
3F |
T7837 |
19150-19151 |
-RRB- |
denotes |
) |
T7838 |
19153-19157 |
RB |
denotes |
Thus |
T7839 |
19157-19158 |
-COMMA- |
denotes |
, |
T7840 |
19159-19163 |
DT |
denotes |
both |
T7841 |
19164-19169 |
NN |
denotes |
sites |
T7842 |
19170-19173 |
VB |
denotes |
are |
T7843 |
19174-19182 |
VB |
denotes |
required |
T7844 |
19183-19186 |
IN |
denotes |
for |
T7845 |
19187-19194 |
JJ |
denotes |
maximal |
T7846 |
19195-19205 |
NN |
denotes |
repression |
T7847 |
19206-19208 |
IN |
denotes |
of |
T7848 |
19209-19211 |
NN |
denotes |
ɛy |
T7849 |
19212-19214 |
IN |
denotes |
by |
T7850 |
19215-19219 |
NN |
denotes |
Sox6 |
T7851 |
19219-19220 |
-COMMA- |
denotes |
, |
T7852 |
19221-19224 |
CC |
denotes |
but |
T7853 |
19225-19228 |
RB |
denotes |
not |
T7854 |
19229-19231 |
TO |
denotes |
to |
T7855 |
19232-19235 |
DT |
denotes |
the |
T7856 |
19236-19240 |
JJ |
denotes |
same |
T7857 |
19241-19247 |
NN |
denotes |
degree |
T7858 |
19249-19251 |
PRP |
denotes |
We |
T7859 |
19252-19256 |
RB |
denotes |
also |
T7860 |
19257-19263 |
VB |
denotes |
tested |
T7861 |
19264-19271 |
IN |
denotes |
whether |
T7862 |
19272-19276 |
NN |
denotes |
Sox6 |
T7863 |
19277-19282 |
VB |
denotes |
binds |
T7864 |
19283-19285 |
TO |
denotes |
to |
T7865 |
19286-19289 |
DT |
denotes |
the |
T7866 |
19290-19292 |
JJ |
denotes |
ɛy |
T7867 |
19293-19301 |
NN |
denotes |
promoter |
T7868 |
19302-19304 |
FW |
denotes |
in |
T7869 |
19305-19309 |
FW |
denotes |
vivo |
T7870 |
19310-19315 |
VB |
denotes |
using |
T7871 |
19316-19325 |
NN |
denotes |
chromatin |
T7872 |
19326-19345 |
NN |
denotes |
immunoprecipitation |
T7873 |
19346-19347 |
-LRB- |
denotes |
( |
T7874 |
19347-19351 |
NN |
denotes |
ChIP |
T7875 |
19351-19352 |
-RRB- |
denotes |
) |
T7876 |
19353-19354 |
-LRB- |
denotes |
( |
T7877 |
19354-19360 |
NN |
denotes |
Figure |
T7878 |
19361-19362 |
CD |
denotes |
4 |
T7879 |
19362-19363 |
-RRB- |
denotes |
) |
T7880 |
19365-19368 |
DT |
denotes |
The |
T7881 |
19369-19384 |
JJ |
denotes |
Sox6-containing |
T7882 |
19385-19392 |
NN |
denotes |
complex |
T7883 |
19393-19396 |
VB |
denotes |
was |
T7884 |
19397-19415 |
VB |
denotes |
immunoprecipitated |
T7885 |
19416-19420 |
IN |
denotes |
from |
T7886 |
19421-19424 |
NN |
denotes |
MEL |
T7887 |
19425-19430 |
NN |
denotes |
cells |
T7888 |
19431-19433 |
CC |
denotes |
or |
T7889 |
19434-19438 |
IN |
denotes |
from |
T7890 |
19439-19444 |
NN |
denotes |
liver |
T7891 |
19445-19450 |
NN |
denotes |
cells |
T7892 |
19451-19453 |
IN |
denotes |
of |
T7893 |
19454-19458 |
CD |
denotes |
15.5 |
T7894 |
19459-19462 |
NN |
denotes |
dpc |
T7895 |
19463-19465 |
JJ |
denotes |
WT |
T7896 |
19466-19470 |
NN |
denotes |
mice |
T7897 |
19471-19476 |
VB |
denotes |
using |
T7898 |
19477-19481 |
NN |
denotes |
Sox6 |
T7899 |
19482-19490 |
NN |
denotes |
antibody |
T7900 |
19492-19498 |
NN |
denotes |
Figure |
T7901 |
19499-19500 |
CD |
denotes |
4 |
T7902 |
19501-19506 |
NN |
denotes |
shows |
T7903 |
19507-19511 |
IN |
denotes |
that |
T7904 |
19512-19515 |
DT |
denotes |
the |
T7905 |
19516-19518 |
JJ |
denotes |
ɛy |
T7906 |
19519-19527 |
JJ |
denotes |
proximal |
T7907 |
19528-19536 |
NN |
denotes |
promoter |
T7908 |
19537-19539 |
VB |
denotes |
is |
T7909 |
19540-19547 |
RB |
denotes |
readily |
T7910 |
19548-19566 |
VB |
denotes |
immunoprecipitated |
T7911 |
19567-19571 |
IN |
denotes |
with |
T7912 |
19572-19576 |
NN |
denotes |
Sox6 |
T7913 |
19577-19585 |
NN |
denotes |
antibody |
T7914 |
19586-19588 |
IN |
denotes |
in |
T7915 |
19589-19593 |
CC |
denotes |
both |
T7916 |
19594-19597 |
NN |
denotes |
MEL |
T7917 |
19598-19603 |
NN |
denotes |
cells |
T7918 |
19604-19607 |
CC |
denotes |
and |
T7919 |
19608-19613 |
NN |
denotes |
liver |
T7920 |
19614-19619 |
NN |
denotes |
cells |
T7921 |
19621-19627 |
JJ |
denotes |
Normal |
T7922 |
19628-19631 |
NN |
denotes |
IgG |
T7923 |
19632-19635 |
VB |
denotes |
was |
T7924 |
19636-19640 |
VB |
denotes |
used |
T7925 |
19641-19643 |
IN |
denotes |
as |
T7926 |
19644-19645 |
DT |
denotes |
a |
T7927 |
19646-19654 |
JJ |
denotes |
negative |
T7928 |
19655-19662 |
NN |
denotes |
control |
T7929 |
19663-19664 |
-LRB- |
denotes |
( |
T7930 |
19664-19670 |
NN |
denotes |
Figure |
T7931 |
19671-19673 |
NN |
denotes |
4A |
T7932 |
19673-19674 |
-RRB- |
denotes |
) |
T7933 |
19676-19679 |
DT |
denotes |
The |
T7934 |
19680-19685 |
JJ |
denotes |
above |
T7935 |
19686-19690 |
NN |
denotes |
data |
T7936 |
19691-19692 |
-LRB- |
denotes |
( |
T7937 |
19692-19699 |
NN |
denotes |
Figures |
T7938 |
19700-19701 |
CD |
denotes |
3 |
T7939 |
19702-19705 |
CC |
denotes |
and |
T7940 |
19706-19707 |
CD |
denotes |
4 |
T7941 |
19707-19708 |
-RRB- |
denotes |
) |
T7942 |
19709-19716 |
RB |
denotes |
clearly |
T7943 |
19717-19725 |
VB |
denotes |
indicate |
T7944 |
19726-19730 |
IN |
denotes |
that |
T7945 |
19731-19735 |
NN |
denotes |
Sox6 |
T7946 |
19736-19740 |
VB |
denotes |
acts |
T7947 |
19741-19743 |
IN |
denotes |
as |
T7948 |
19744-19745 |
DT |
denotes |
a |
T7949 |
19746-19755 |
NN |
denotes |
repressor |
T7950 |
19756-19758 |
IN |
denotes |
of |
T7951 |
19759-19762 |
DT |
denotes |
the |
T7952 |
19763-19765 |
JJ |
denotes |
ɛy |
T7953 |
19766-19770 |
NN |
denotes |
gene |
T7954 |
19771-19773 |
IN |
denotes |
by |
T7955 |
19774-19782 |
RB |
denotes |
directly |
T7956 |
19783-19790 |
VB |
denotes |
binding |
T7957 |
19791-19793 |
TO |
denotes |
to |
T7958 |
19794-19797 |
DT |
denotes |
the |
T7959 |
19798-19800 |
JJ |
denotes |
ɛy |
T7960 |
19801-19809 |
NN |
denotes |
promoter |
T7961 |
19809-19810 |
-COMMA- |
denotes |
, |
T7962 |
19811-19819 |
RB |
denotes |
probably |
T7963 |
19820-19822 |
IN |
denotes |
as |
T7964 |
19823-19824 |
DT |
denotes |
a |
T7965 |
19825-19830 |
NN |
denotes |
dimer |
T9129 |
20660-20663 |
DT |
denotes |
The |
T9130 |
20664-20674 |
JJ |
denotes |
Persistent |
T9131 |
20675-20685 |
NN |
denotes |
Expression |
T9132 |
20686-20688 |
IN |
denotes |
of |
T9133 |
20689-20691 |
JJ |
denotes |
ɛy |
T9134 |
20692-20698 |
NN |
denotes |
Globin |
T9135 |
20699-20701 |
IN |
denotes |
in |
T9136 |
20702-20716 |
JJ |
denotes |
Sox6-Deficient |
T9137 |
20717-20721 |
NN |
denotes |
Mice |
T9138 |
20722-20724 |
VB |
denotes |
Is |
T9139 |
20725-20728 |
JJ |
denotes |
Due |
T9140 |
20729-20731 |
TO |
denotes |
to |
T9141 |
20732-20733 |
DT |
denotes |
a |
T9142 |
20734-20740 |
NN |
denotes |
Defect |
T9143 |
20741-20743 |
IN |
denotes |
in |
T9144 |
20744-20747 |
DT |
denotes |
the |
T9145 |
20748-20765 |
JJ |
denotes |
ɛy-Gene–Silencing |
T9146 |
20766-20775 |
NN |
denotes |
Mechanism |
T9147 |
20776-20778 |
IN |
denotes |
in |
T9148 |
20779-20789 |
JJ |
denotes |
Definitive |
T9149 |
20790-20799 |
JJ |
denotes |
Erythroid |
T9150 |
20800-20805 |
NN |
denotes |
Cells |
T9151 |
20806-20814 |
RB |
denotes |
Normally |
T9152 |
20814-20815 |
-COMMA- |
denotes |
, |
T9153 |
20816-20819 |
DT |
denotes |
the |
T9154 |
20820-20822 |
JJ |
denotes |
ɛy |
T9155 |
20823-20829 |
NN |
denotes |
globin |
T9156 |
20830-20834 |
NN |
denotes |
gene |
T9157 |
20835-20837 |
VB |
denotes |
is |
T9158 |
20838-20849 |
RB |
denotes |
exclusively |
T9159 |
20850-20859 |
VB |
denotes |
expressed |
T9160 |
20860-20862 |
IN |
denotes |
in |
T9161 |
20863-20872 |
JJ |
denotes |
primitive |
T9162 |
20873-20885 |
NN |
denotes |
erythrocytes |
T9163 |
20886-20889 |
CC |
denotes |
and |
T9164 |
20890-20898 |
JJ |
denotes |
silenced |
T9165 |
20899-20901 |
IN |
denotes |
in |
T9166 |
20902-20912 |
JJ |
denotes |
definitive |
T9167 |
20913-20925 |
NN |
denotes |
erythrocytes |
T9168 |
20927-20929 |
TO |
denotes |
To |
T9169 |
20930-20939 |
VB |
denotes |
determine |
T9170 |
20940-20947 |
IN |
denotes |
whether |
T9171 |
20948-20951 |
DT |
denotes |
the |
T9172 |
20952-20962 |
JJ |
denotes |
persistent |
T9173 |
20963-20973 |
NN |
denotes |
expression |
T9174 |
20974-20976 |
IN |
denotes |
of |
T9175 |
20977-20979 |
JJ |
denotes |
ɛy |
T9176 |
20980-20986 |
NN |
denotes |
globin |
T9177 |
20987-20989 |
VB |
denotes |
is |
T9178 |
20990-20993 |
JJ |
denotes |
due |
T9179 |
20994-20996 |
TO |
denotes |
to |
T9180 |
20997-21005 |
JJ |
denotes |
residual |
T9181 |
21006-21015 |
JJ |
denotes |
primitive |
T9182 |
21016-21028 |
NN |
denotes |
erythrocytes |
T9183 |
21029-21031 |
CC |
denotes |
or |
T9184 |
21032-21034 |
VB |
denotes |
is |
T9185 |
21035-21038 |
JJ |
denotes |
due |
T9186 |
21039-21041 |
TO |
denotes |
to |
T9187 |
21042-21049 |
JJ |
denotes |
ectopic |
T9188 |
21050-21060 |
NN |
denotes |
expression |
T9189 |
21061-21063 |
IN |
denotes |
of |
T9190 |
21064-21066 |
JJ |
denotes |
ɛy |
T9191 |
21067-21073 |
NN |
denotes |
globin |
T9192 |
21074-21076 |
IN |
denotes |
in |
T9193 |
21077-21087 |
JJ |
denotes |
definitive |
T9194 |
21088-21100 |
NN |
denotes |
erythrocytes |
T9195 |
21100-21101 |
-COMMA- |
denotes |
, |
T9196 |
21102-21104 |
PRP |
denotes |
we |
T9197 |
21105-21113 |
VB |
denotes |
examined |
T9198 |
21114-21117 |
DT |
denotes |
the |
T9199 |
21118-21125 |
JJ |
denotes |
spatial |
T9200 |
21126-21133 |
NN |
denotes |
pattern |
T9201 |
21134-21136 |
IN |
denotes |
of |
T9202 |
21137-21139 |
JJ |
denotes |
ɛy |
T9203 |
21140-21146 |
NN |
denotes |
globin |
T9204 |
21147-21158 |
NN |
denotes |
transcripts |
T9205 |
21159-21161 |
IN |
denotes |
in |
T9206 |
21162-21167 |
NN |
denotes |
mouse |
T9207 |
21168-21175 |
NN |
denotes |
embryos |
T9208 |
21176-21178 |
IN |
denotes |
by |
T9209 |
21179-21181 |
FW |
denotes |
in |
T9210 |
21182-21186 |
FW |
denotes |
situ |
T9211 |
21187-21200 |
NN |
denotes |
hybridization |
T9212 |
21201-21202 |
-LRB- |
denotes |
( |
T9213 |
21202-21208 |
NN |
denotes |
Figure |
T9214 |
21209-21210 |
CD |
denotes |
5 |
T9215 |
21210-21211 |
-RRB- |
denotes |
) |
T9216 |
21213-21215 |
IN |
denotes |
As |
T9217 |
21216-21224 |
VB |
denotes |
expected |
T9218 |
21224-21225 |
-COMMA- |
denotes |
, |
T9219 |
21226-21228 |
JJ |
denotes |
ɛy |
T9220 |
21229-21235 |
NN |
denotes |
globin |
T9221 |
21236-21238 |
VB |
denotes |
is |
T9222 |
21239-21242 |
RB |
denotes |
not |
T9223 |
21243-21252 |
VB |
denotes |
expressed |
T9224 |
21253-21255 |
IN |
denotes |
in |
T9225 |
21256-21259 |
DT |
denotes |
the |
T9226 |
21260-21262 |
NN |
denotes |
WT |
T9227 |
21263-21271 |
NN |
denotes |
14.5-dpc |
T9228 |
21272-21277 |
NN |
denotes |
liver |
T9229 |
21277-21278 |
-COMMA- |
denotes |
, |
T9230 |
21279-21282 |
DT |
denotes |
the |
T9231 |
21283-21287 |
NN |
denotes |
site |
T9232 |
21288-21290 |
IN |
denotes |
of |
T9233 |
21291-21301 |
JJ |
denotes |
definitive |
T9234 |
21302-21316 |
NN |
denotes |
erythropoiesis |
T9235 |
21317-21319 |
IN |
denotes |
in |
T9236 |
21320-21323 |
DT |
denotes |
the |
T9237 |
21324-21329 |
NN |
denotes |
fetus |
T9238 |
21331-21333 |
IN |
denotes |
In |
T9239 |
21334-21342 |
NN |
denotes |
contrast |
T9240 |
21342-21343 |
-COMMA- |
denotes |
, |
T9241 |
21344-21352 |
JJ |
denotes |
abundant |
T9242 |
21353-21360 |
JJ |
denotes |
ectopic |
T9243 |
21361-21363 |
JJ |
denotes |
ɛy |
T9244 |
21364-21368 |
NN |
denotes |
mRNA |
T9245 |
21369-21379 |
NN |
denotes |
expression |
T9246 |
21380-21382 |
VB |
denotes |
is |
T9247 |
21383-21387 |
VB |
denotes |
seen |
T9248 |
21388-21390 |
IN |
denotes |
in |
T9249 |
21391-21394 |
DT |
denotes |
the |
T9250 |
21395-21400 |
NN |
denotes |
liver |
T9251 |
21401-21403 |
IN |
denotes |
of |
T9252 |
21404-21412 |
JJ |
denotes |
14.5-dpc |
T9253 |
21413-21420 |
NN |
denotes |
mutants |
T9254 |
21421-21422 |
-LRB- |
denotes |
( |
T9255 |
21422-21428 |
NN |
denotes |
Figure |
T9256 |
21429-21430 |
CD |
denotes |
5 |
T9257 |
21431-21434 |
NN |
denotes |
A–D |
T9258 |
21434-21435 |
-RRB- |
denotes |
) |
T9259 |
21437-21444 |
RB |
denotes |
However |
T9260 |
21444-21445 |
-COMMA- |
denotes |
, |
T9261 |
21446-21449 |
DT |
denotes |
the |
T9262 |
21450-21460 |
NN |
denotes |
expression |
T9263 |
21461-21463 |
IN |
denotes |
of |
T9264 |
21464-21472 |
NN |
denotes |
βmaj/min |
T9265 |
21473-21479 |
NN |
denotes |
globin |
T9266 |
21480-21482 |
VB |
denotes |
is |
T9267 |
21483-21490 |
RB |
denotes |
equally |
T9268 |
21491-21499 |
JJ |
denotes |
abundant |
T9269 |
21500-21502 |
IN |
denotes |
in |
T9270 |
21503-21507 |
CC |
denotes |
both |
T9271 |
21508-21510 |
NN |
denotes |
WT |
T9272 |
21511-21514 |
CC |
denotes |
and |
T9273 |
21515-21520 |
NN |
denotes |
p100H |
T9274 |
21521-21527 |
JJ |
denotes |
mutant |
T9275 |
21528-21532 |
NN |
denotes |
mice |
T9276 |
21533-21534 |
-LRB- |
denotes |
( |
T9277 |
21534-21540 |
NN |
denotes |
Figure |
T9278 |
21541-21542 |
CD |
denotes |
5 |
T9279 |
21543-21544 |
NN |
denotes |
E |
T9280 |
21545-21548 |
CC |
denotes |
and |
T9281 |
21549-21550 |
NN |
denotes |
F |
T9282 |
21550-21551 |
-RRB- |
denotes |
) |
T9283 |
21553-21558 |
DT |
denotes |
These |
T9284 |
21559-21563 |
NN |
denotes |
data |
T9285 |
21564-21575 |
VB |
denotes |
demonstrate |
T9286 |
21576-21580 |
IN |
denotes |
that |
T9287 |
21581-21584 |
DT |
denotes |
the |
T9288 |
21585-21595 |
JJ |
denotes |
persistent |
T9289 |
21596-21600 |
JJ |
denotes |
high |
T9290 |
21601-21607 |
NN |
denotes |
levels |
T9291 |
21608-21610 |
IN |
denotes |
of |
T9292 |
21611-21613 |
NN |
denotes |
ɛy |
T9293 |
21614-21617 |
VB |
denotes |
are |
T9294 |
21618-21621 |
JJ |
denotes |
due |
T9295 |
21622-21624 |
TO |
denotes |
to |
T9296 |
21625-21632 |
JJ |
denotes |
ectopic |
T9297 |
21633-21643 |
NN |
denotes |
expression |
T9298 |
21644-21646 |
IN |
denotes |
in |
T9299 |
21647-21650 |
DT |
denotes |
the |
T9300 |
21651-21661 |
JJ |
denotes |
definitive |
T9301 |
21662-21671 |
JJ |
denotes |
erythroid |
T9302 |
21672-21677 |
NN |
denotes |
cells |
T9303 |
21678-21682 |
WDT |
denotes |
that |
T9304 |
21683-21689 |
VB |
denotes |
mature |
T9305 |
21690-21692 |
IN |
denotes |
in |
T9306 |
21693-21696 |
DT |
denotes |
the |
T9307 |
21697-21702 |
JJ |
denotes |
fetal |
T9308 |
21703-21708 |
NN |
denotes |
liver |
T9309 |
21708-21709 |
-COMMA- |
denotes |
, |
T9310 |
21710-21720 |
VB |
denotes |
suggesting |
T9311 |
21721-21725 |
IN |
denotes |
that |
T9312 |
21726-21731 |
EX |
denotes |
there |
T9313 |
21732-21734 |
VB |
denotes |
is |
T9314 |
21735-21737 |
DT |
denotes |
an |
T9315 |
21738-21747 |
JJ |
denotes |
intrinsic |
T9316 |
21748-21754 |
NN |
denotes |
defect |
T9317 |
21755-21757 |
IN |
denotes |
of |
T9318 |
21758-21761 |
DT |
denotes |
the |
T9319 |
21762-21764 |
JJ |
denotes |
ɛy |
T9320 |
21765-21774 |
NN |
denotes |
silencing |
T9321 |
21775-21784 |
NN |
denotes |
mechanism |
T9322 |
21785-21787 |
IN |
denotes |
in |
T9323 |
21788-21797 |
JJ |
denotes |
Sox6-null |
T9324 |
21798-21802 |
NN |
denotes |
mice |
T9862 |
22433-22436 |
DT |
denotes |
The |
T9863 |
22437-22447 |
NN |
denotes |
Expression |
T9864 |
22448-22455 |
NN |
denotes |
Pattern |
T9865 |
22456-22458 |
IN |
denotes |
of |
T9866 |
22459-22463 |
NN |
denotes |
Sox6 |
T9867 |
22464-22472 |
VB |
denotes |
Suggests |
T9868 |
22473-22474 |
DT |
denotes |
a |
T9869 |
22475-22479 |
NN |
denotes |
Role |
T9870 |
22480-22482 |
IN |
denotes |
in |
T9871 |
22483-22493 |
JJ |
denotes |
Definitive |
T9872 |
22494-22508 |
NN |
denotes |
Erythropoiesis |
T9873 |
22509-22512 |
DT |
denotes |
The |
T9874 |
22513-22524 |
NN |
denotes |
observation |
T9875 |
22525-22529 |
IN |
denotes |
that |
T9876 |
22530-22544 |
JJ |
denotes |
Sox6-deficient |
T9877 |
22545-22549 |
NN |
denotes |
mice |
T9878 |
22550-22561 |
RB |
denotes |
ectopically |
T9879 |
22562-22569 |
VB |
denotes |
express |
T9880 |
22570-22572 |
JJ |
denotes |
ɛy |
T9881 |
22573-22579 |
NN |
denotes |
globin |
T9882 |
22580-22582 |
IN |
denotes |
in |
T9883 |
22583-22588 |
NN |
denotes |
liver |
T9884 |
22588-22589 |
-COMMA- |
denotes |
, |
T9885 |
22590-22595 |
WRB |
denotes |
where |
T9886 |
22596-22606 |
JJ |
denotes |
definitive |
T9887 |
22607-22616 |
JJ |
denotes |
erythroid |
T9888 |
22617-22622 |
NN |
denotes |
cells |
T9889 |
22623-22629 |
VB |
denotes |
mature |
T9890 |
22629-22630 |
-COMMA- |
denotes |
, |
T9891 |
22631-22639 |
VB |
denotes |
suggests |
T9892 |
22640-22644 |
IN |
denotes |
that |
T9893 |
22645-22649 |
NN |
denotes |
Sox6 |
T9894 |
22650-22652 |
VB |
denotes |
is |
T9895 |
22653-22655 |
DT |
denotes |
an |
T9896 |
22656-22665 |
JJ |
denotes |
important |
T9897 |
22666-22675 |
NN |
denotes |
regulator |
T9898 |
22676-22678 |
IN |
denotes |
in |
T9899 |
22679-22689 |
JJ |
denotes |
definitive |
T9900 |
22690-22704 |
NN |
denotes |
erythropoiesis |
T9901 |
22706-22708 |
TO |
denotes |
To |
T9902 |
22709-22718 |
VB |
denotes |
determine |
T9903 |
22719-22722 |
DT |
denotes |
the |
T9904 |
22723-22731 |
JJ |
denotes |
temporal |
T9905 |
22732-22735 |
CC |
denotes |
and |
T9906 |
22736-22743 |
JJ |
denotes |
spatial |
T9907 |
22744-22754 |
NN |
denotes |
expression |
T9908 |
22755-22762 |
NN |
denotes |
pattern |
T9909 |
22763-22765 |
IN |
denotes |
of |
T9910 |
22766-22770 |
NN |
denotes |
Sox6 |
T9911 |
22770-22771 |
-COMMA- |
denotes |
, |
T9912 |
22772-22780 |
NN |
denotes |
Northern |
T9913 |
22781-22785 |
NN |
denotes |
blot |
T9914 |
22786-22789 |
CC |
denotes |
and |
T9915 |
22790-22792 |
FW |
denotes |
in |
T9916 |
22793-22797 |
FW |
denotes |
situ |
T9917 |
22798-22811 |
NN |
denotes |
hybridization |
T9918 |
22812-22818 |
NN |
denotes |
assays |
T9919 |
22819-22823 |
VB |
denotes |
were |
T9920 |
22824-22832 |
VB |
denotes |
employed |
T9921 |
22834-22836 |
IN |
denotes |
As |
T9922 |
22837-22842 |
VB |
denotes |
shown |
T9923 |
22843-22845 |
IN |
denotes |
in |
T9924 |
22846-22852 |
NN |
denotes |
Figure |
T9925 |
22853-22855 |
NN |
denotes |
6A |
T9926 |
22855-22856 |
-COMMA- |
denotes |
, |
T9927 |
22857-22861 |
NN |
denotes |
Sox6 |
T9928 |
22862-22864 |
VB |
denotes |
is |
T9929 |
22865-22875 |
JJ |
denotes |
detectable |
T9930 |
22876-22878 |
IN |
denotes |
by |
T9931 |
22879-22887 |
JJ |
denotes |
Northern |
T9932 |
22888-22892 |
NN |
denotes |
blot |
T9933 |
22893-22902 |
VB |
denotes |
beginning |
T9934 |
22903-22905 |
IN |
denotes |
at |
T9935 |
22906-22910 |
CD |
denotes |
10.5 |
T9936 |
22911-22914 |
NN |
denotes |
dpc |
T9937 |
22914-22915 |
-COMMA- |
denotes |
, |
T9938 |
22916-22926 |
JJ |
denotes |
coincident |
T9939 |
22927-22931 |
IN |
denotes |
with |
T9940 |
22932-22935 |
DT |
denotes |
the |
T9941 |
22936-22944 |
JJ |
denotes |
temporal |
T9942 |
22945-22950 |
NN |
denotes |
onset |
T9943 |
22951-22953 |
IN |
denotes |
of |
T9944 |
22954-22964 |
JJ |
denotes |
definitive |
T9945 |
22965-22979 |
NN |
denotes |
erythropoiesis |
T9946 |
22980-22982 |
IN |
denotes |
in |
T9947 |
22983-22986 |
DT |
denotes |
the |
T9948 |
22987-22992 |
NN |
denotes |
liver |
T9949 |
22994-23005 |
RB |
denotes |
Furthermore |
T9950 |
23005-23006 |
-COMMA- |
denotes |
, |
T9951 |
23007-23009 |
FW |
denotes |
in |
T9952 |
23010-23014 |
FW |
denotes |
situ |
T9953 |
23015-23028 |
NN |
denotes |
hybridization |
T9954 |
23029-23034 |
VB |
denotes |
shows |
T9955 |
23035-23039 |
IN |
denotes |
that |
T9956 |
23040-23044 |
NN |
denotes |
Sox6 |
T9957 |
23045-23047 |
VB |
denotes |
is |
T9958 |
23048-23054 |
RB |
denotes |
highly |
T9959 |
23055-23066 |
VB |
denotes |
transcribed |
T9960 |
23067-23069 |
IN |
denotes |
in |
T9961 |
23070-23078 |
NN |
denotes |
12.5-dpc |
T9962 |
23079-23084 |
NN |
denotes |
liver |
T9963 |
23084-23085 |
-COMMA- |
denotes |
, |
T9964 |
23086-23089 |
CC |
denotes |
but |
T9965 |
23090-23093 |
RB |
denotes |
not |
T9966 |
23094-23096 |
IN |
denotes |
in |
T9967 |
23097-23101 |
NN |
denotes |
yolk |
T9968 |
23102-23105 |
NN |
denotes |
sac |
T9969 |
23106-23111 |
NN |
denotes |
blood |
T9970 |
23112-23119 |
NN |
denotes |
islands |
T9971 |
23120-23122 |
IN |
denotes |
at |
T9972 |
23123-23126 |
CD |
denotes |
7.5 |
T9973 |
23127-23130 |
NN |
denotes |
dpc |
T9974 |
23131-23132 |
-LRB- |
denotes |
( |
T9975 |
23132-23138 |
NN |
denotes |
Figure |
T9976 |
23139-23141 |
NN |
denotes |
6B |
T9977 |
23141-23142 |
-RRB- |
denotes |
) |
T9978 |
23144-23153 |
RB |
denotes |
Therefore |
T9979 |
23153-23154 |
-COMMA- |
denotes |
, |
T9980 |
23155-23159 |
NN |
denotes |
Sox6 |
T9981 |
23160-23170 |
NN |
denotes |
expression |
T9982 |
23171-23173 |
VB |
denotes |
is |
T9983 |
23174-23184 |
RB |
denotes |
temporally |
T9984 |
23185-23188 |
CC |
denotes |
and |
T9985 |
23189-23198 |
RB |
denotes |
spatially |
T9986 |
23199-23209 |
JJ |
denotes |
coincident |
T9987 |
23210-23214 |
IN |
denotes |
with |
T9988 |
23215-23225 |
JJ |
denotes |
definitive |
T9989 |
23225-23226 |
-COMMA- |
denotes |
, |
T9990 |
23227-23230 |
CC |
denotes |
but |
T9991 |
23231-23234 |
RB |
denotes |
not |
T9992 |
23235-23244 |
JJ |
denotes |
primitive |
T9993 |
23244-23245 |
-COMMA- |
denotes |
, |
T9994 |
23246-23260 |
NN |
denotes |
erythropoiesis |
T9995 |
23262-23267 |
DT |
denotes |
These |
T9996 |
23268-23272 |
NN |
denotes |
data |
T9997 |
23272-23273 |
-COMMA- |
denotes |
, |
T9998 |
23274-23279 |
VB |
denotes |
taken |
T9999 |
23280-23288 |
RB |
denotes |
together |
T10000 |
23289-23293 |
IN |
denotes |
with |
T10001 |
23294-23297 |
DT |
denotes |
the |
T10002 |
23298-23309 |
NN |
denotes |
observation |
T10003 |
23310-23314 |
IN |
denotes |
that |
T10004 |
23315-23317 |
JJ |
denotes |
ɛy |
T10005 |
23318-23324 |
NN |
denotes |
globin |
T10006 |
23325-23327 |
VB |
denotes |
is |
T10007 |
23328-23334 |
RB |
denotes |
highly |
T10008 |
23335-23344 |
VB |
denotes |
expressed |
T10009 |
23345-23347 |
IN |
denotes |
in |
T10010 |
23348-23351 |
DT |
denotes |
the |
T10011 |
23352-23357 |
NN |
denotes |
liver |
T10012 |
23358-23363 |
NN |
denotes |
cells |
T10013 |
23364-23366 |
IN |
denotes |
of |
T10014 |
23367-23375 |
JJ |
denotes |
14.5-dpc |
T10015 |
23376-23381 |
NN |
denotes |
p100H |
T10016 |
23382-23388 |
JJ |
denotes |
mutant |
T10017 |
23389-23393 |
NN |
denotes |
mice |
T10018 |
23394-23395 |
-LRB- |
denotes |
( |
T10019 |
23395-23401 |
NN |
denotes |
Figure |
T10020 |
23402-23403 |
CD |
denotes |
5 |
T10021 |
23403-23404 |
-RRB- |
denotes |
) |
T10022 |
23404-23405 |
-COMMA- |
denotes |
, |
T10023 |
23406-23417 |
VB |
denotes |
demonstrate |
T10024 |
23418-23422 |
IN |
denotes |
that |
T10025 |
23423-23427 |
NN |
denotes |
Sox6 |
T10026 |
23428-23437 |
NN |
denotes |
functions |
T10027 |
23438-23440 |
IN |
denotes |
in |
T10028 |
23441-23451 |
JJ |
denotes |
definitive |
T10029 |
23452-23466 |
NN |
denotes |
erythropoiesis |
T10371 |
24516-24522 |
JJ |
denotes |
Mutant |
T10372 |
24523-24528 |
NN |
denotes |
p100H |
T10373 |
24529-24533 |
NNP |
denotes |
Mice |
T10374 |
24534-24538 |
NNP |
denotes |
Have |
T10375 |
24539-24545 |
NNP |
denotes |
Higher |
T10376 |
24546-24553 |
NNP |
denotes |
Numbers |
T10377 |
24554-24556 |
IN |
denotes |
of |
T10378 |
24557-24566 |
NNP |
denotes |
Nucleated |
T10379 |
24567-24570 |
NNP |
denotes |
Red |
T10380 |
24571-24576 |
NNP |
denotes |
Cells |
T10381 |
24577-24582 |
IN |
denotes |
Among |
T10382 |
24583-24586 |
DT |
denotes |
the |
T10383 |
24587-24592 |
JJ |
denotes |
other |
T10384 |
24593-24597 |
NN |
denotes |
Sox6 |
T10385 |
24598-24605 |
NN |
denotes |
effects |
T10386 |
24606-24608 |
IN |
denotes |
in |
T10387 |
24609-24623 |
NN |
denotes |
erythropoiesis |
T10388 |
24623-24624 |
-COMMA- |
denotes |
, |
T10389 |
24625-24627 |
PRP |
denotes |
we |
T10390 |
24628-24632 |
VB |
denotes |
have |
T10391 |
24633-24640 |
VB |
denotes |
noticed |
T10392 |
24641-24645 |
IN |
denotes |
that |
T10393 |
24646-24651 |
EX |
denotes |
there |
T10394 |
24652-24655 |
VB |
denotes |
are |
T10395 |
24656-24660 |
RB |
denotes |
more |
T10396 |
24661-24670 |
JJ |
denotes |
nucleated |
T10397 |
24671-24674 |
JJ |
denotes |
red |
T10398 |
24675-24680 |
NN |
denotes |
blood |
T10399 |
24681-24686 |
NN |
denotes |
cells |
T10400 |
24687-24698 |
VB |
denotes |
circulating |
T10401 |
24699-24701 |
IN |
denotes |
in |
T10402 |
24702-24707 |
NN |
denotes |
p100H |
T10403 |
24708-24714 |
JJ |
denotes |
mutant |
T10404 |
24715-24719 |
NN |
denotes |
mice |
T10405 |
24720-24724 |
IN |
denotes |
than |
T10406 |
24725-24727 |
IN |
denotes |
in |
T10407 |
24728-24730 |
JJ |
denotes |
WT |
T10408 |
24731-24735 |
NN |
denotes |
mice |
T10409 |
24736-24738 |
IN |
denotes |
at |
T10410 |
24739-24743 |
CD |
denotes |
14.5 |
T10411 |
24744-24747 |
NN |
denotes |
dpc |
T10412 |
24748-24751 |
CC |
denotes |
and |
T10413 |
24752-24756 |
CD |
denotes |
18.5 |
T10414 |
24757-24760 |
NN |
denotes |
dpc |
T10415 |
24761-24762 |
-LRB- |
denotes |
( |
T10416 |
24762-24768 |
NN |
denotes |
Figure |
T10417 |
24769-24771 |
NN |
denotes |
7A |
T10418 |
24771-24772 |
-RRB- |
denotes |
) |
T10419 |
24774-24781 |
RB |
denotes |
However |
T10420 |
24781-24782 |
-COMMA- |
denotes |
, |
T10421 |
24783-24785 |
IN |
denotes |
at |
T10422 |
24786-24795 |
JJ |
denotes |
postnatal |
T10423 |
24796-24799 |
NN |
denotes |
day |
T10424 |
24800-24804 |
CD |
denotes |
10.5 |
T10425 |
24804-24805 |
-COMMA- |
denotes |
, |
T10426 |
24806-24808 |
PRP |
denotes |
we |
T10427 |
24809-24811 |
VB |
denotes |
do |
T10428 |
24812-24815 |
RB |
denotes |
not |
T10429 |
24816-24819 |
VB |
denotes |
see |
T10430 |
24820-24831 |
VB |
denotes |
circulating |
T10431 |
24832-24841 |
JJ |
denotes |
nucleated |
T10432 |
24842-24845 |
JJ |
denotes |
red |
T10433 |
24846-24851 |
NN |
denotes |
cells |
T10434 |
24852-24854 |
IN |
denotes |
in |
T10435 |
24855-24861 |
CC |
denotes |
either |
T10436 |
24862-24864 |
NN |
denotes |
WT |
T10437 |
24865-24867 |
CC |
denotes |
or |
T10438 |
24868-24874 |
JJ |
denotes |
mutant |
T10439 |
24875-24879 |
NN |
denotes |
mice |
T10440 |
24879-24880 |
-COMMA- |
denotes |
, |
T10441 |
24881-24891 |
VB |
denotes |
suggesting |
T10442 |
24892-24896 |
IN |
denotes |
that |
T10443 |
24897-24901 |
DT |
denotes |
this |
T10444 |
24902-24905 |
MD |
denotes |
may |
T10445 |
24906-24908 |
VB |
denotes |
be |
T10446 |
24909-24910 |
DT |
denotes |
a |
T10447 |
24911-24920 |
JJ |
denotes |
transient |
T10448 |
24921-24927 |
NN |
denotes |
effect |
T10449 |
24929-24931 |
IN |
denotes |
In |
T10450 |
24932-24940 |
NN |
denotes |
addition |
T10451 |
24940-24941 |
-COMMA- |
denotes |
, |
T10452 |
24942-24945 |
DT |
denotes |
the |
T10453 |
24946-24952 |
JJ |
denotes |
mutant |
T10454 |
24953-24958 |
NN |
denotes |
liver |
T10455 |
24959-24964 |
VB |
denotes |
shows |
T10456 |
24965-24966 |
DT |
denotes |
a |
T10457 |
24967-24978 |
JJ |
denotes |
significant |
T10458 |
24979-24987 |
NN |
denotes |
increase |
T10459 |
24988-24990 |
IN |
denotes |
in |
T10460 |
24991-25004 |
JJ |
denotes |
hematopoietic |
T10461 |
25005-25014 |
NN |
denotes |
precursor |
T10462 |
25015-25020 |
NN |
denotes |
cells |
T10463 |
25021-25030 |
VB |
denotes |
including |
T10464 |
25031-25040 |
JJ |
denotes |
nucleated |
T10465 |
25041-25053 |
NN |
denotes |
erythrocytes |
T10466 |
25054-25056 |
IN |
denotes |
at |
T10467 |
25057-25061 |
CD |
denotes |
18.5 |
T10468 |
25062-25065 |
NN |
denotes |
dpc |
T10469 |
25066-25067 |
-LRB- |
denotes |
( |
T10470 |
25067-25073 |
NN |
denotes |
Figure |
T10471 |
25074-25076 |
NN |
denotes |
7B |
T10472 |
25076-25077 |
-RRB- |
denotes |
) |
T10473 |
25079-25083 |
DT |
denotes |
This |
T10474 |
25084-25094 |
NN |
denotes |
alteration |
T10475 |
25095-25097 |
VB |
denotes |
is |
T10476 |
25098-25103 |
VB |
denotes |
noted |
T10477 |
25104-25106 |
RB |
denotes |
as |
T10478 |
25107-25112 |
RB |
denotes |
early |
T10479 |
25113-25115 |
IN |
denotes |
as |
T10480 |
25116-25120 |
CD |
denotes |
14.5 |
T10481 |
25121-25124 |
NN |
denotes |
dpc |
T10482 |
25126-25131 |
DT |
denotes |
These |
T10483 |
25132-25144 |
NN |
denotes |
observations |
T10484 |
25145-25152 |
VB |
denotes |
suggest |
T10485 |
25153-25157 |
IN |
denotes |
that |
T10486 |
25158-25165 |
IN |
denotes |
besides |
T10487 |
25166-25175 |
VB |
denotes |
silencing |
T10488 |
25176-25179 |
DT |
denotes |
the |
T10489 |
25180-25182 |
JJ |
denotes |
ɛy |
T10490 |
25183-25189 |
NN |
denotes |
globin |
T10491 |
25190-25194 |
NN |
denotes |
gene |
T10492 |
25194-25195 |
-COMMA- |
denotes |
, |
T10493 |
25196-25200 |
NN |
denotes |
Sox6 |
T10494 |
25201-25204 |
MD |
denotes |
may |
T10495 |
25205-25211 |
VB |
denotes |
affect |
T10496 |
25212-25215 |
JJ |
denotes |
red |
T10497 |
25216-25220 |
NN |
denotes |
cell |
T10498 |
25221-25231 |
NN |
denotes |
maturation |
T11818 |
25551-25553 |
IN |
denotes |
In |
T11819 |
25554-25558 |
DT |
denotes |
this |
T11820 |
25559-25565 |
NN |
denotes |
report |
T11821 |
25565-25566 |
-COMMA- |
denotes |
, |
T11822 |
25567-25569 |
PRP |
denotes |
we |
T11823 |
25570-25574 |
VB |
denotes |
show |
T11824 |
25575-25579 |
IN |
denotes |
that |
T11825 |
25580-25584 |
NN |
denotes |
Sox6 |
T11826 |
25585-25587 |
VB |
denotes |
is |
T11827 |
25588-25589 |
DT |
denotes |
a |
T11828 |
25590-25595 |
JJ |
denotes |
novel |
T11829 |
25596-25602 |
NN |
denotes |
factor |
T11830 |
25603-25605 |
IN |
denotes |
in |
T11831 |
25606-25609 |
DT |
denotes |
the |
T11832 |
25610-25621 |
VB |
denotes |
complicated |
T11833 |
25622-25632 |
NN |
denotes |
regulation |
T11834 |
25633-25642 |
NN |
denotes |
mechanism |
T11835 |
25643-25645 |
IN |
denotes |
of |
T11836 |
25646-25652 |
NN |
denotes |
globin |
T11837 |
25653-25658 |
NN |
denotes |
genes |
T11838 |
25660-25662 |
IN |
denotes |
In |
T11839 |
25663-25666 |
DT |
denotes |
the |
T11840 |
25667-25671 |
NN |
denotes |
Sox6 |
T11841 |
25672-25676 |
JJ |
denotes |
null |
T11842 |
25677-25682 |
NN |
denotes |
mouse |
T11843 |
25682-25683 |
-COMMA- |
denotes |
, |
T11844 |
25684-25689 |
EX |
denotes |
there |
T11845 |
25690-25692 |
VB |
denotes |
is |
T11846 |
25693-25694 |
DT |
denotes |
a |
T11847 |
25695-25704 |
JJ |
denotes |
transient |
T11848 |
25705-25711 |
NN |
denotes |
effect |
T11849 |
25712-25714 |
IN |
denotes |
on |
T11850 |
25715-25718 |
DT |
denotes |
the |
T11851 |
25719-25728 |
JJ |
denotes |
embryonic |
T11852 |
25729-25735 |
NN |
denotes |
globin |
T11853 |
25736-25741 |
NN |
denotes |
genes |
T11854 |
25741-25742 |
-COMMA- |
denotes |
, |
T11855 |
25743-25744 |
NN |
denotes |
ζ |
T11856 |
25745-25748 |
CC |
denotes |
and |
T11857 |
25749-25752 |
NN |
denotes |
βH1 |
T11858 |
25752-25753 |
-COMMA- |
denotes |
, |
T11859 |
25754-25757 |
CC |
denotes |
and |
T11860 |
25758-25759 |
DT |
denotes |
a |
T11861 |
25760-25770 |
JJ |
denotes |
persistent |
T11862 |
25771-25783 |
NN |
denotes |
upregulation |
T11863 |
25784-25786 |
IN |
denotes |
of |
T11864 |
25787-25790 |
DT |
denotes |
the |
T11865 |
25791-25793 |
JJ |
denotes |
ɛy |
T11866 |
25794-25800 |
NN |
denotes |
globin |
T11867 |
25801-25805 |
NN |
denotes |
gene |
T11868 |
25807-25811 |
NN |
denotes |
Sox6 |
T11869 |
25812-25820 |
RB |
denotes |
directly |
T11870 |
25821-25830 |
VB |
denotes |
regulates |
T11871 |
25831-25834 |
CC |
denotes |
and |
T11872 |
25835-25840 |
VB |
denotes |
binds |
T11873 |
25841-25843 |
TO |
denotes |
to |
T11874 |
25844-25847 |
DT |
denotes |
the |
T11875 |
25848-25856 |
JJ |
denotes |
proximal |
T11876 |
25857-25865 |
NN |
denotes |
promoter |
T11877 |
25866-25868 |
IN |
denotes |
of |
T11878 |
25869-25871 |
JJ |
denotes |
ɛy |
T11879 |
25872-25876 |
NN |
denotes |
gene |
T11880 |
25877-25880 |
CC |
denotes |
and |
T11881 |
25881-25890 |
VB |
denotes |
represses |
T11882 |
25891-25894 |
DT |
denotes |
the |
T11883 |
25895-25904 |
JJ |
denotes |
ɛy-globin |
T11884 |
25905-25909 |
NN |
denotes |
gene |
T11885 |
25910-25912 |
IN |
denotes |
in |
T11886 |
25913-25923 |
JJ |
denotes |
definitive |
T11887 |
25924-25938 |
NN |
denotes |
erythropoiesis |
T11888 |
25940-25944 |
NN |
denotes |
Sox6 |
T11889 |
25945-25952 |
VB |
denotes |
belongs |
T11890 |
25953-25955 |
TO |
denotes |
to |
T11891 |
25956-25961 |
NN |
denotes |
group |
T11892 |
25962-25963 |
NN |
denotes |
D |
T11893 |
25964-25966 |
IN |
denotes |
of |
T11894 |
25967-25970 |
DT |
denotes |
the |
T11895 |
25971-25974 |
NNP |
denotes |
Sox |
T11896 |
25975-25981 |
NN |
denotes |
family |
T11897 |
25982-25984 |
IN |
denotes |
of |
T11898 |
25985-25993 |
NN |
denotes |
proteins |
T11899 |
25994-25998 |
WDT |
denotes |
that |
T11900 |
25999-26007 |
VB |
denotes |
includes |
T11901 |
26008-26012 |
NN |
denotes |
Sox5 |
T11902 |
26012-26013 |
-COMMA- |
denotes |
, |
T11903 |
26014-26016 |
CD |
denotes |
12 |
T11904 |
26016-26017 |
-COMMA- |
denotes |
, |
T11905 |
26018-26020 |
CD |
denotes |
13 |
T11906 |
26020-26021 |
-COMMA- |
denotes |
, |
T11907 |
26022-26025 |
CC |
denotes |
and |
T11908 |
26026-26028 |
CD |
denotes |
23 |
T11909 |
26029-26030 |
-LRB- |
denotes |
[ |
T11910 |
26030-26032 |
CD |
denotes |
34 |
T11911 |
26032-26033 |
-RRB- |
denotes |
] |
T11912 |
26035-26040 |
NNP |
denotes |
Group |
T11913 |
26041-26042 |
NNP |
denotes |
D |
T11914 |
26043-26046 |
NNP |
denotes |
Sox |
T11915 |
26047-26055 |
NN |
denotes |
proteins |
T11916 |
26056-26063 |
VB |
denotes |
contain |
T11917 |
26064-26065 |
DT |
denotes |
a |
T11918 |
26066-26079 |
JJ |
denotes |
coiled–coiled |
T11919 |
26080-26086 |
NN |
denotes |
domain |
T11920 |
26087-26091 |
WDT |
denotes |
that |
T11921 |
26092-26100 |
VB |
denotes |
mediates |
T11922 |
26101-26106 |
JJ |
denotes |
homo- |
T11923 |
26107-26110 |
CC |
denotes |
and |
T11924 |
26111-26129 |
NN |
denotes |
heterodimerization |
T11925 |
26130-26131 |
-LRB- |
denotes |
[ |
T11926 |
26131-26135 |
CD |
denotes |
6,35 |
T11927 |
26135-26136 |
-RRB- |
denotes |
] |
T11928 |
26138-26150 |
RB |
denotes |
Functionally |
T11929 |
26150-26151 |
-COMMA- |
denotes |
, |
T11930 |
26152-26164 |
NN |
denotes |
dimerization |
T11931 |
26165-26167 |
IN |
denotes |
of |
T11932 |
26168-26172 |
NN |
denotes |
Sox5 |
T11933 |
26173-26176 |
CC |
denotes |
and |
T11934 |
26177-26181 |
NN |
denotes |
Sox6 |
T11935 |
26182-26185 |
VB |
denotes |
has |
T11936 |
26186-26190 |
VB |
denotes |
been |
T11937 |
26191-26196 |
VB |
denotes |
shown |
T11938 |
26197-26199 |
TO |
denotes |
to |
T11939 |
26200-26207 |
RB |
denotes |
greatly |
T11940 |
26208-26216 |
VB |
denotes |
increase |
T11941 |
26217-26220 |
DT |
denotes |
the |
T11942 |
26221-26228 |
VB |
denotes |
binding |
T11943 |
26229-26239 |
NN |
denotes |
efficiency |
T11944 |
26240-26242 |
IN |
denotes |
of |
T11945 |
26243-26246 |
DT |
denotes |
the |
T11946 |
26247-26250 |
CD |
denotes |
two |
T11947 |
26251-26254 |
NN |
denotes |
Sox |
T11948 |
26255-26263 |
NN |
denotes |
proteins |
T11949 |
26264-26266 |
TO |
denotes |
to |
T11950 |
26267-26270 |
NN |
denotes |
DNA |
T11951 |
26271-26275 |
WDT |
denotes |
that |
T11952 |
26276-26284 |
VB |
denotes |
contains |
T11953 |
26285-26293 |
JJ |
denotes |
adjacent |
T11954 |
26294-26297 |
NN |
denotes |
Sox |
T11955 |
26298-26303 |
NN |
denotes |
sites |
T11956 |
26304-26305 |
-LRB- |
denotes |
[ |
T11957 |
26305-26306 |
CD |
denotes |
6 |
T11958 |
26306-26307 |
-RRB- |
denotes |
] |
T11959 |
26309-26311 |
IN |
denotes |
In |
T11960 |
26312-26320 |
NN |
denotes |
addition |
T11961 |
26320-26321 |
-COMMA- |
denotes |
, |
T11962 |
26322-26326 |
NN |
denotes |
Sox6 |
T11963 |
26327-26332 |
VB |
denotes |
binds |
T11964 |
26333-26337 |
RB |
denotes |
more |
T11965 |
26338-26346 |
RB |
denotes |
strongly |
T11966 |
26347-26349 |
TO |
denotes |
to |
T11967 |
26350-26352 |
DT |
denotes |
an |
T11968 |
26353-26360 |
NN |
denotes |
HMG-box |
T11969 |
26361-26366 |
NN |
denotes |
dimer |
T11970 |
26367-26372 |
NN |
denotes |
motif |
T11971 |
26373-26377 |
IN |
denotes |
than |
T11972 |
26378-26380 |
TO |
denotes |
to |
T11973 |
26381-26382 |
DT |
denotes |
a |
T11974 |
26383-26389 |
JJ |
denotes |
single |
T11975 |
26390-26397 |
NN |
denotes |
HMG-box |
T11976 |
26398-26403 |
NN |
denotes |
motif |
T11977 |
26404-26405 |
-LRB- |
denotes |
[ |
T11978 |
26405-26406 |
CD |
denotes |
5 |
T11979 |
26406-26407 |
-RRB- |
denotes |
] |
T11980 |
26409-26418 |
RB |
denotes |
Therefore |
T11981 |
26418-26419 |
-COMMA- |
denotes |
, |
T11982 |
26420-26422 |
PRP |
denotes |
it |
T11983 |
26423-26430 |
VB |
denotes |
appears |
T11984 |
26431-26435 |
IN |
denotes |
that |
T11985 |
26436-26442 |
NN |
denotes |
target |
T11986 |
26443-26448 |
NN |
denotes |
genes |
T11987 |
26449-26452 |
IN |
denotes |
for |
T11988 |
26453-26458 |
NN |
denotes |
group |
T11989 |
26459-26460 |
NN |
denotes |
D |
T11990 |
26461-26464 |
NN |
denotes |
Sox |
T11991 |
26465-26473 |
NN |
denotes |
proteins |
T11992 |
26473-26474 |
-COMMA- |
denotes |
, |
T11993 |
26475-26479 |
JJ |
denotes |
such |
T11994 |
26480-26482 |
IN |
denotes |
as |
T11995 |
26483-26487 |
NN |
denotes |
Sox6 |
T11996 |
26487-26488 |
-COMMA- |
denotes |
, |
T11997 |
26489-26497 |
RB |
denotes |
probably |
T11998 |
26498-26504 |
VB |
denotes |
harbor |
T11999 |
26505-26510 |
NN |
denotes |
pairs |
T12000 |
26511-26513 |
IN |
denotes |
of |
T12001 |
26514-26517 |
NN |
denotes |
HMG |
T12002 |
26518-26525 |
NN |
denotes |
binding |
T12003 |
26526-26531 |
NN |
denotes |
sites |
T12004 |
26532-26536 |
IN |
denotes |
with |
T12005 |
26537-26538 |
DT |
denotes |
a |
T12006 |
26539-26552 |
NN |
denotes |
configuration |
T12007 |
26553-26563 |
JJ |
denotes |
compatible |
T12008 |
26564-26568 |
IN |
denotes |
with |
T12009 |
26569-26576 |
NN |
denotes |
binding |
T12010 |
26577-26579 |
IN |
denotes |
of |
T12011 |
26580-26585 |
NN |
denotes |
D-Sox |
T12012 |
26586-26593 |
NN |
denotes |
protein |
T12013 |
26594-26600 |
NN |
denotes |
dimers |
T12014 |
26602-26608 |
RB |
denotes |
Indeed |
T12015 |
26608-26609 |
-COMMA- |
denotes |
, |
T12016 |
26610-26612 |
IN |
denotes |
in |
T12017 |
26613-26616 |
DT |
denotes |
the |
T12018 |
26617-26624 |
JJ |
denotes |
present |
T12019 |
26625-26630 |
NN |
denotes |
study |
T12020 |
26630-26631 |
-COMMA- |
denotes |
, |
T12021 |
26632-26635 |
DT |
denotes |
the |
T12022 |
26636-26643 |
VB |
denotes |
defined |
T12023 |
26644-26648 |
NN |
denotes |
Sox6 |
T12024 |
26649-26655 |
NN |
denotes |
target |
T12025 |
26656-26664 |
NN |
denotes |
sequence |
T12026 |
26665-26667 |
IN |
denotes |
of |
T12027 |
26668-26671 |
DT |
denotes |
the |
T12028 |
26672-26674 |
JJ |
denotes |
ɛy |
T12029 |
26675-26683 |
NN |
denotes |
promoter |
T12030 |
26684-26692 |
VB |
denotes |
contains |
T12031 |
26693-26696 |
CD |
denotes |
two |
T12032 |
26697-26705 |
NN |
denotes |
Sox/Sox6 |
T12033 |
26706-26715 |
NN |
denotes |
consensus |
T12034 |
26716-26721 |
NN |
denotes |
sites |
T12035 |
26722-26723 |
-LRB- |
denotes |
( |
T12036 |
26723-26729 |
NN |
denotes |
Figure |
T12037 |
26730-26732 |
NN |
denotes |
3A |
T12038 |
26732-26733 |
-RRB- |
denotes |
) |
T12039 |
26735-26747 |
RB |
denotes |
Functionally |
T12040 |
26747-26748 |
-COMMA- |
denotes |
, |
T12041 |
26749-26753 |
DT |
denotes |
both |
T12042 |
26754-26759 |
NN |
denotes |
sites |
T12043 |
26760-26763 |
VB |
denotes |
are |
T12044 |
26764-26773 |
JJ |
denotes |
essential |
T12045 |
26774-26777 |
IN |
denotes |
for |
T12046 |
26778-26782 |
NN |
denotes |
Sox6 |
T12047 |
26783-26790 |
NN |
denotes |
binding |
T12048 |
26791-26793 |
TO |
denotes |
to |
T12049 |
26794-26797 |
DT |
denotes |
the |
T12050 |
26798-26800 |
JJ |
denotes |
ɛy |
T12051 |
26801-26809 |
NN |
denotes |
promoter |
T12052 |
26810-26813 |
CC |
denotes |
and |
T12053 |
26814-26824 |
NN |
denotes |
repression |
T12054 |
26825-26827 |
IN |
denotes |
of |
T12055 |
26828-26831 |
PRP-DOLLAR- |
denotes |
its |
T12056 |
26832-26840 |
NN |
denotes |
activity |
T12057 |
26841-26842 |
-LRB- |
denotes |
( |
T12058 |
26842-26848 |
NN |
denotes |
Figure |
T12059 |
26849-26851 |
NN |
denotes |
3E |
T12060 |
26852-26855 |
CC |
denotes |
and |
T12061 |
26856-26858 |
NN |
denotes |
3F |
T12062 |
26858-26859 |
-RRB- |
denotes |
) |
T12063 |
26861-26866 |
DT |
denotes |
These |
T12064 |
26867-26879 |
NN |
denotes |
observations |
T12065 |
26880-26887 |
VB |
denotes |
suggest |
T12066 |
26888-26892 |
IN |
denotes |
that |
T12067 |
26893-26897 |
NN |
denotes |
Sox6 |
T12068 |
26898-26903 |
VB |
denotes |
binds |
T12069 |
26904-26906 |
TO |
denotes |
to |
T12070 |
26907-26911 |
DT |
denotes |
this |
T12071 |
26912-26920 |
NN |
denotes |
sequence |
T12072 |
26921-26923 |
IN |
denotes |
of |
T12073 |
26924-26927 |
DT |
denotes |
the |
T12074 |
26928-26930 |
JJ |
denotes |
ɛy |
T12075 |
26931-26939 |
NN |
denotes |
promoter |
T12076 |
26940-26946 |
CC |
denotes |
either |
T12077 |
26947-26949 |
IN |
denotes |
as |
T12078 |
26950-26951 |
DT |
denotes |
a |
T12079 |
26952-26961 |
NN |
denotes |
homodimer |
T12080 |
26962-26964 |
CC |
denotes |
or |
T12081 |
26965-26967 |
IN |
denotes |
as |
T12082 |
26968-26969 |
DT |
denotes |
a |
T12083 |
26970-26981 |
NN |
denotes |
heterodimer |
T12084 |
26982-26986 |
IN |
denotes |
with |
T12085 |
26987-26992 |
JJ |
denotes |
other |
T12086 |
26993-26996 |
NN |
denotes |
Sox |
T12087 |
26997-27005 |
NN |
denotes |
proteins |
T12088 |
27007-27014 |
IN |
denotes |
Because |
T12089 |
27015-27018 |
NN |
denotes |
Sox |
T12090 |
27019-27027 |
NN |
denotes |
proteins |
T12091 |
27028-27037 |
VB |
denotes |
recognize |
T12092 |
27038-27039 |
DT |
denotes |
a |
T12093 |
27040-27045 |
JJ |
denotes |
short |
T12094 |
27046-27050 |
JJ |
denotes |
6-bp |
T12095 |
27051-27063 |
JJ |
denotes |
core-binding |
T12096 |
27064-27072 |
NN |
denotes |
sequence |
T12097 |
27073-27077 |
WDT |
denotes |
that |
T12098 |
27078-27084 |
VB |
denotes |
allows |
T12099 |
27085-27088 |
IN |
denotes |
for |
T12100 |
27089-27101 |
JJ |
denotes |
considerable |
T12101 |
27102-27112 |
NN |
denotes |
degeneracy |
T12102 |
27112-27113 |
-COMMA- |
denotes |
, |
T12103 |
27114-27117 |
DT |
denotes |
the |
T12104 |
27118-27129 |
NN |
denotes |
specificity |
T12105 |
27130-27132 |
IN |
denotes |
of |
T12106 |
27133-27138 |
PRP-DOLLAR- |
denotes |
their |
T12107 |
27139-27146 |
NN |
denotes |
actions |
T12108 |
27147-27149 |
VB |
denotes |
is |
T12109 |
27150-27157 |
VB |
denotes |
thought |
T12110 |
27158-27160 |
TO |
denotes |
to |
T12111 |
27161-27165 |
VB |
denotes |
rely |
T12112 |
27166-27170 |
IN |
denotes |
upon |
T12113 |
27171-27183 |
NN |
denotes |
interactions |
T12114 |
27184-27188 |
IN |
denotes |
with |
T12115 |
27189-27194 |
JJ |
denotes |
other |
T12116 |
27195-27208 |
NN |
denotes |
transcription |
T12117 |
27209-27216 |
NN |
denotes |
factors |
T12118 |
27217-27218 |
-LRB- |
denotes |
[ |
T12119 |
27218-27220 |
CD |
denotes |
36 |
T12120 |
27220-27221 |
-RRB- |
denotes |
] |
T12121 |
27223-27225 |
IN |
denotes |
In |
T12122 |
27226-27229 |
PRP-DOLLAR- |
denotes |
our |
T12123 |
27230-27235 |
NN |
denotes |
EMSAs |
T12124 |
27235-27236 |
-COMMA- |
denotes |
, |
T12125 |
27237-27239 |
PRP |
denotes |
we |
T12126 |
27240-27243 |
VB |
denotes |
had |
T12127 |
27244-27246 |
TO |
denotes |
to |
T12128 |
27247-27250 |
VB |
denotes |
run |
T12129 |
27251-27254 |
DT |
denotes |
the |
T12130 |
27255-27270 |
NN |
denotes |
electrophoresis |
T12131 |
27271-27273 |
IN |
denotes |
on |
T12132 |
27274-27275 |
DT |
denotes |
a |
T12133 |
27276-27277 |
CD |
denotes |
4 |
T12134 |
27277-27278 |
NN |
denotes |
% |
T12135 |
27278-27280 |
CD |
denotes |
–6 |
T12136 |
27280-27281 |
NN |
denotes |
% |
T12137 |
27282-27285 |
NN |
denotes |
gel |
T12138 |
27286-27289 |
IN |
denotes |
for |
T12139 |
27290-27292 |
IN |
denotes |
at |
T12140 |
27293-27298 |
JJ |
denotes |
least |
T12141 |
27299-27302 |
CD |
denotes |
4–8 |
T12142 |
27303-27304 |
NN |
denotes |
h |
T12143 |
27305-27307 |
TO |
denotes |
to |
T12144 |
27308-27314 |
VB |
denotes |
detect |
T12145 |
27315-27318 |
DT |
denotes |
the |
T12146 |
27319-27334 |
JJ |
denotes |
Sox6-associated |
T12147 |
27335-27339 |
NN |
denotes |
band |
T12148 |
27339-27340 |
-COMMA- |
denotes |
, |
T12149 |
27341-27351 |
VB |
denotes |
suggesting |
T12150 |
27352-27356 |
IN |
denotes |
that |
T12151 |
27357-27361 |
NN |
denotes |
Sox6 |
T12152 |
27362-27364 |
VB |
denotes |
is |
T12153 |
27365-27369 |
NN |
denotes |
part |
T12154 |
27370-27372 |
IN |
denotes |
of |
T12155 |
27373-27374 |
DT |
denotes |
a |
T12156 |
27375-27379 |
JJ |
denotes |
high |
T12157 |
27380-27389 |
JJ |
denotes |
molecular |
T12158 |
27390-27396 |
NN |
denotes |
weight |
T12159 |
27397-27404 |
NN |
denotes |
complex |
T12160 |
27406-27407 |
DT |
denotes |
A |
T12161 |
27408-27411 |
JJ |
denotes |
few |
T12162 |
27412-27417 |
JJ |
denotes |
other |
T12163 |
27418-27420 |
JJ |
denotes |
ɛy |
T12164 |
27421-27427 |
NN |
denotes |
globin |
T12165 |
27428-27438 |
NN |
denotes |
repressors |
T12166 |
27439-27443 |
VB |
denotes |
have |
T12167 |
27444-27448 |
VB |
denotes |
been |
T12168 |
27449-27457 |
VB |
denotes |
reported |
T12169 |
27458-27460 |
TO |
denotes |
to |
T12170 |
27461-27465 |
VB |
denotes |
bind |
T12171 |
27466-27468 |
TO |
denotes |
to |
T12172 |
27469-27472 |
NN |
denotes |
DNA |
T12173 |
27473-27482 |
NN |
denotes |
sequences |
T12174 |
27483-27487 |
IN |
denotes |
near |
T12175 |
27488-27491 |
DT |
denotes |
the |
T12176 |
27492-27500 |
NN |
denotes |
Sox/Sox6 |
T12177 |
27501-27510 |
NN |
denotes |
consensus |
T12178 |
27511-27516 |
NN |
denotes |
sites |
T12179 |
27516-27517 |
-COMMA- |
denotes |
, |
T12180 |
27518-27527 |
VB |
denotes |
including |
T12181 |
27528-27531 |
DT |
denotes |
the |
T12182 |
27532-27536 |
JJ |
denotes |
DRED |
T12183 |
27537-27544 |
NN |
denotes |
complex |
T12184 |
27545-27546 |
-LRB- |
denotes |
[ |
T12185 |
27546-27548 |
CD |
denotes |
37 |
T12186 |
27548-27549 |
-RRB- |
denotes |
] |
T12187 |
27550-27553 |
CC |
denotes |
and |
T12188 |
27554-27561 |
NN |
denotes |
COUP-TF |
T12189 |
27562-27563 |
-LRB- |
denotes |
[ |
T12190 |
27563-27565 |
CD |
denotes |
38 |
T12191 |
27565-27566 |
-RRB- |
denotes |
] |
T12192 |
27568-27572 |
NN |
denotes |
Sox6 |
T12193 |
27573-27578 |
MD |
denotes |
might |
T12194 |
27579-27587 |
VB |
denotes |
interact |
T12195 |
27588-27592 |
IN |
denotes |
with |
T12196 |
27593-27598 |
DT |
denotes |
these |
T12197 |
27599-27606 |
NN |
denotes |
factors |
T12198 |
27607-27610 |
CC |
denotes |
and |
T12199 |
27611-27615 |
VB |
denotes |
form |
T12200 |
27616-27617 |
DT |
denotes |
a |
T12201 |
27618-27623 |
JJ |
denotes |
large |
T12202 |
27624-27634 |
NN |
denotes |
repression |
T12203 |
27635-27642 |
NN |
denotes |
complex |
T12204 |
27644-27658 |
NN |
denotes |
Identification |
T12205 |
27659-27661 |
IN |
denotes |
of |
T12206 |
27662-27667 |
JJ |
denotes |
other |
T12207 |
27668-27678 |
NN |
denotes |
components |
T12208 |
27679-27681 |
IN |
denotes |
of |
T12209 |
27682-27685 |
DT |
denotes |
the |
T12210 |
27686-27701 |
JJ |
denotes |
Sox6-containing |
T12211 |
27702-27709 |
NN |
denotes |
complex |
T12212 |
27710-27720 |
VB |
denotes |
associated |
T12213 |
27721-27725 |
IN |
denotes |
with |
T12214 |
27726-27729 |
DT |
denotes |
the |
T12215 |
27730-27732 |
JJ |
denotes |
ɛy |
T12216 |
27733-27741 |
NN |
denotes |
promoter |
T12217 |
27742-27746 |
MD |
denotes |
will |
T12218 |
27747-27751 |
VB |
denotes |
shed |
T12219 |
27752-27757 |
NN |
denotes |
light |
T12220 |
27758-27760 |
IN |
denotes |
on |
T12221 |
27761-27764 |
PRP-DOLLAR- |
denotes |
its |
T12222 |
27765-27774 |
NN |
denotes |
mechanism |
T12223 |
27775-27777 |
IN |
denotes |
of |
T12224 |
27778-27788 |
NN |
denotes |
repression |
T12225 |
27790-27793 |
NN |
denotes |
Sox |
T12226 |
27794-27802 |
NN |
denotes |
proteins |
T12227 |
27803-27807 |
VB |
denotes |
bind |
T12228 |
27808-27811 |
CC |
denotes |
and |
T12229 |
27812-27816 |
VB |
denotes |
bend |
T12230 |
27817-27823 |
JJ |
denotes |
linear |
T12231 |
27824-27827 |
NN |
denotes |
DNA |
T12232 |
27828-27830 |
IN |
denotes |
by |
T12233 |
27831-27838 |
JJ |
denotes |
partial |
T12234 |
27839-27852 |
NN |
denotes |
intercalation |
T12235 |
27853-27855 |
IN |
denotes |
in |
T12236 |
27856-27859 |
DT |
denotes |
the |
T12237 |
27860-27865 |
JJ |
denotes |
minor |
T12238 |
27866-27872 |
NN |
denotes |
groove |
T12239 |
27872-27873 |
-COMMA- |
denotes |
, |
T12240 |
27874-27877 |
CC |
denotes |
and |
T12241 |
27878-27881 |
MD |
denotes |
can |
T12242 |
27882-27886 |
RB |
denotes |
also |
T12243 |
27887-27891 |
VB |
denotes |
bind |
T12244 |
27892-27894 |
TO |
denotes |
to |
T12245 |
27895-27903 |
JJ |
denotes |
four-way |
T12246 |
27904-27913 |
NN |
denotes |
junctions |
T12247 |
27914-27915 |
-LRB- |
denotes |
[ |
T12248 |
27915-27918 |
CD |
denotes |
2–4 |
T12249 |
27918-27919 |
-RRB- |
denotes |
] |
T12250 |
27921-27930 |
RB |
denotes |
Therefore |
T12251 |
27930-27931 |
-COMMA- |
denotes |
, |
T12252 |
27932-27935 |
CD |
denotes |
one |
T12253 |
27936-27946 |
JJ |
denotes |
attractive |
T12254 |
27947-27952 |
NN |
denotes |
model |
T12255 |
27953-27955 |
TO |
denotes |
to |
T12256 |
27956-27963 |
VB |
denotes |
explain |
T12257 |
27964-27967 |
WRB |
denotes |
how |
T12258 |
27968-27972 |
NN |
denotes |
Sox6 |
T12259 |
27973-27981 |
NN |
denotes |
proteins |
T12260 |
27982-27989 |
VB |
denotes |
control |
T12261 |
27990-27994 |
NN |
denotes |
gene |
T12262 |
27995-28005 |
NN |
denotes |
expression |
T12263 |
28006-28008 |
VB |
denotes |
is |
T12264 |
28009-28013 |
IN |
denotes |
that |
T12265 |
28014-28018 |
PRP |
denotes |
they |
T12266 |
28019-28027 |
VB |
denotes |
function |
T12267 |
28028-28030 |
IN |
denotes |
as |
T12268 |
28031-28044 |
JJ |
denotes |
architectural |
T12269 |
28045-28052 |
NN |
denotes |
factors |
T12270 |
28053-28058 |
VB |
denotes |
bound |
T12271 |
28059-28061 |
TO |
denotes |
to |
T12272 |
28062-28065 |
NN |
denotes |
DNA |
T12273 |
28065-28066 |
-COMMA- |
denotes |
, |
T12274 |
28067-28078 |
VB |
denotes |
influencing |
T12275 |
28079-28084 |
JJ |
denotes |
local |
T12276 |
28085-28094 |
NN |
denotes |
chromatin |
T12277 |
28095-28104 |
NN |
denotes |
structure |
T12278 |
28105-28107 |
IN |
denotes |
by |
T12279 |
28108-28115 |
VB |
denotes |
bending |
T12280 |
28116-28119 |
NN |
denotes |
DNA |
T12281 |
28120-28123 |
CC |
denotes |
and |
T12282 |
28124-28126 |
IN |
denotes |
by |
T12283 |
28127-28137 |
VB |
denotes |
assembling |
T12284 |
28138-28150 |
NN |
denotes |
multiprotein |
T12285 |
28151-28166 |
JJ |
denotes |
transcriptional |
T12286 |
28167-28176 |
NN |
denotes |
complexes |
T12287 |
28178-28180 |
IN |
denotes |
By |
T12288 |
28181-28189 |
VB |
denotes |
changing |
T12289 |
28190-28193 |
DT |
denotes |
the |
T12290 |
28194-28199 |
JJ |
denotes |
local |
T12291 |
28200-28209 |
NN |
denotes |
chromatin |
T12292 |
28210-28219 |
NN |
denotes |
structure |
T12293 |
28219-28220 |
-COMMA- |
denotes |
, |
T12294 |
28221-28225 |
NN |
denotes |
Sox6 |
T12295 |
28226-28231 |
MD |
denotes |
could |
T12296 |
28232-28238 |
RB |
denotes |
either |
T12297 |
28239-28248 |
VB |
denotes |
interfere |
T12298 |
28249-28253 |
IN |
denotes |
with |
T12299 |
28254-28261 |
NN |
denotes |
binding |
T12300 |
28262-28264 |
IN |
denotes |
of |
T12301 |
28265-28270 |
JJ |
denotes |
other |
T12302 |
28271-28281 |
NN |
denotes |
activators |
T12303 |
28282-28284 |
TO |
denotes |
to |
T12304 |
28285-28288 |
DT |
denotes |
the |
T12305 |
28289-28297 |
NN |
denotes |
promoter |
T12306 |
28298-28300 |
CC |
denotes |
or |
T12307 |
28301-28311 |
VB |
denotes |
facilitate |
T12308 |
28312-28319 |
NN |
denotes |
binding |
T12309 |
28320-28322 |
IN |
denotes |
of |
T12310 |
28323-28328 |
JJ |
denotes |
other |
T12311 |
28329-28339 |
NN |
denotes |
repressors |
T12312 |
28341-28348 |
DT |
denotes |
Another |
T12313 |
28349-28356 |
NN |
denotes |
example |
T12314 |
28357-28359 |
IN |
denotes |
of |
T12315 |
28360-28361 |
DT |
denotes |
a |
T12316 |
28362-28371 |
NN |
denotes |
repressor |
T12317 |
28372-28376 |
WDT |
denotes |
that |
T12318 |
28377-28387 |
VB |
denotes |
interferes |
T12319 |
28388-28392 |
IN |
denotes |
with |
T12320 |
28393-28395 |
DT |
denotes |
an |
T12321 |
28396-28405 |
NN |
denotes |
activator |
T12322 |
28406-28408 |
IN |
denotes |
on |
T12323 |
28409-28412 |
DT |
denotes |
the |
T12324 |
28413-28415 |
JJ |
denotes |
ɛy |
T12325 |
28416-28424 |
NN |
denotes |
promoter |
T12326 |
28425-28427 |
VB |
denotes |
is |
T12327 |
28428-28432 |
VB |
denotes |
DRED |
T12328 |
28434-28438 |
VB |
denotes |
DRED |
T12329 |
28439-28449 |
VB |
denotes |
interferes |
T12330 |
28450-28454 |
IN |
denotes |
with |
T12331 |
28455-28459 |
NN |
denotes |
EKLF |
T12332 |
28459-28460 |
-COMMA- |
denotes |
, |
T12333 |
28461-28463 |
DT |
denotes |
an |
T12334 |
28464-28473 |
NN |
denotes |
activator |
T12335 |
28473-28474 |
-COMMA- |
denotes |
, |
T12336 |
28475-28477 |
IN |
denotes |
in |
T12337 |
28478-28485 |
VB |
denotes |
binding |
T12338 |
28486-28488 |
TO |
denotes |
to |
T12339 |
28489-28492 |
DT |
denotes |
the |
T12340 |
28493-28495 |
JJ |
denotes |
ɛy |
T12341 |
28496-28504 |
NN |
denotes |
promoter |
T12342 |
28505-28506 |
-LRB- |
denotes |
[ |
T12343 |
28506-28508 |
CD |
denotes |
39 |
T12344 |
28508-28509 |
-RRB- |
denotes |
] |
T12345 |
28511-28514 |
CD |
denotes |
Two |
T12346 |
28515-28518 |
NN |
denotes |
HMG |
T12347 |
28519-28532 |
JJ |
denotes |
architectural |
T12348 |
28533-28541 |
NN |
denotes |
proteins |
T12349 |
28542-28543 |
-LRB- |
denotes |
( |
T12350 |
28543-28552 |
RB |
denotes |
distantly |
T12351 |
28553-28560 |
VB |
denotes |
related |
T12352 |
28561-28563 |
TO |
denotes |
to |
T12353 |
28564-28567 |
DT |
denotes |
the |
T12354 |
28568-28571 |
NN |
denotes |
Sox |
T12355 |
28572-28578 |
NN |
denotes |
family |
T12356 |
28579-28581 |
IN |
denotes |
of |
T12357 |
28582-28595 |
NN |
denotes |
transcription |
T12358 |
28596-28603 |
NN |
denotes |
factors |
T12359 |
28603-28604 |
-RRB- |
denotes |
) |
T12360 |
28604-28605 |
-COMMA- |
denotes |
, |
T12361 |
28606-28611 |
NN |
denotes |
HMG-I |
T12362 |
28612-28615 |
CC |
denotes |
and |
T12363 |
28616-28621 |
NN |
denotes |
HMG-Y |
T12364 |
28621-28622 |
-COMMA- |
denotes |
, |
T12365 |
28623-28627 |
VB |
denotes |
were |
T12366 |
28628-28640 |
VB |
denotes |
demonstrated |
T12367 |
28641-28643 |
TO |
denotes |
to |
T12368 |
28644-28648 |
VB |
denotes |
bind |
T12369 |
28649-28651 |
TO |
denotes |
to |
T12370 |
28652-28655 |
DT |
denotes |
the |
T12371 |
28656-28661 |
JJ |
denotes |
human |
T12372 |
28662-28667 |
JJ |
denotes |
adult |
T12373 |
28668-28669 |
NN |
denotes |
β |
T12374 |
28670-28676 |
NN |
denotes |
globin |
T12375 |
28677-28686 |
NN |
denotes |
silencers |
T12376 |
28687-28688 |
-LRB- |
denotes |
( |
T12377 |
28688-28697 |
NN |
denotes |
silencers |
T12378 |
28698-28699 |
CD |
denotes |
I |
T12379 |
28700-28703 |
CC |
denotes |
and |
T12380 |
28704-28706 |
CD |
denotes |
II |
T12381 |
28706-28707 |
-RRB- |
denotes |
) |
T12382 |
28708-28711 |
CC |
denotes |
and |
T12383 |
28712-28717 |
VB |
denotes |
cause |
T12384 |
28718-28725 |
VB |
denotes |
bending |
T12385 |
28726-28728 |
IN |
denotes |
of |
T12386 |
28729-28732 |
DT |
denotes |
the |
T12387 |
28733-28736 |
NN |
denotes |
DNA |
T12388 |
28736-28737 |
-COMMA- |
denotes |
, |
T12389 |
28738-28750 |
VB |
denotes |
facilitating |
T12390 |
28751-28754 |
DT |
denotes |
the |
T12391 |
28755-28762 |
NN |
denotes |
binding |
T12392 |
28763-28765 |
IN |
denotes |
of |
T12393 |
28766-28771 |
JJ |
denotes |
other |
T12394 |
28772-28782 |
NN |
denotes |
repressors |
T12395 |
28783-28784 |
-LRB- |
denotes |
[ |
T12396 |
28784-28786 |
CD |
denotes |
40 |
T12397 |
28786-28787 |
-RRB- |
denotes |
] |
T12398 |
28789-28793 |
NN |
denotes |
Sox6 |
T12399 |
28794-28804 |
NN |
denotes |
expression |
T12400 |
28805-28807 |
VB |
denotes |
is |
T12401 |
28808-28818 |
RB |
denotes |
temporally |
T12402 |
28819-28822 |
CC |
denotes |
and |
T12403 |
28823-28832 |
RB |
denotes |
spatially |
T12404 |
28833-28843 |
JJ |
denotes |
coincident |
T12405 |
28844-28848 |
IN |
denotes |
with |
T12406 |
28849-28859 |
JJ |
denotes |
definitive |
T12407 |
28860-28861 |
-LRB- |
denotes |
( |
T12408 |
28861-28864 |
CC |
denotes |
but |
T12409 |
28865-28868 |
RB |
denotes |
not |
T12410 |
28869-28878 |
JJ |
denotes |
primitive |
T12411 |
28878-28879 |
-RRB- |
denotes |
) |
T12412 |
28880-28894 |
NN |
denotes |
erythropoiesis |
T12413 |
28895-28896 |
-LRB- |
denotes |
( |
T12414 |
28896-28902 |
NN |
denotes |
Figure |
T12415 |
28903-28904 |
CD |
denotes |
6 |
T12416 |
28904-28905 |
-RRB- |
denotes |
) |
T12417 |
28905-28906 |
-COMMA- |
denotes |
, |
T12418 |
28907-28910 |
CC |
denotes |
and |
T12419 |
28911-28915 |
NN |
denotes |
Sox6 |
T12420 |
28916-28925 |
VB |
denotes |
represses |
T12421 |
28926-28928 |
JJ |
denotes |
ɛy |
T12422 |
28929-28935 |
NN |
denotes |
globin |
T12423 |
28936-28946 |
NN |
denotes |
expression |
T12424 |
28947-28951 |
CC |
denotes |
both |
T12425 |
28952-28954 |
FW |
denotes |
in |
T12426 |
28955-28959 |
FW |
denotes |
vivo |
T12427 |
28960-28961 |
-LRB- |
denotes |
( |
T12428 |
28961-28967 |
NN |
denotes |
Figure |
T12429 |
28968-28969 |
CD |
denotes |
1 |
T12430 |
28969-28970 |
-RRB- |
denotes |
) |
T12431 |
28971-28974 |
CC |
denotes |
and |
T12432 |
28975-28977 |
FW |
denotes |
in |
T12433 |
28978-28983 |
FW |
denotes |
vitro |
T12434 |
28984-28985 |
-LRB- |
denotes |
( |
T12435 |
28985-28991 |
NN |
denotes |
Figure |
T12436 |
28992-28993 |
CD |
denotes |
2 |
T12437 |
28993-28994 |
-RRB- |
denotes |
) |
T12438 |
28996-29004 |
RB |
denotes |
Moreover |
T12439 |
29004-29005 |
-COMMA- |
denotes |
, |
T12440 |
29006-29008 |
FW |
denotes |
in |
T12441 |
29009-29013 |
FW |
denotes |
situ |
T12442 |
29014-29027 |
NN |
denotes |
hybridization |
T12443 |
29028-29035 |
RB |
denotes |
clearly |
T12444 |
29036-29041 |
VB |
denotes |
shows |
T12445 |
29042-29046 |
IN |
denotes |
that |
T12446 |
29047-29050 |
DT |
denotes |
the |
T12447 |
29051-29061 |
JJ |
denotes |
persistent |
T12448 |
29062-29072 |
NN |
denotes |
expression |
T12449 |
29073-29075 |
IN |
denotes |
of |
T12450 |
29076-29078 |
JJ |
denotes |
ɛy |
T12451 |
29079-29085 |
NN |
denotes |
globin |
T12452 |
29086-29088 |
IN |
denotes |
in |
T12453 |
29089-29094 |
NN |
denotes |
p100H |
T12454 |
29095-29101 |
JJ |
denotes |
mutant |
T12455 |
29102-29106 |
NN |
denotes |
mice |
T12456 |
29107-29109 |
VB |
denotes |
is |
T12457 |
29110-29113 |
IN |
denotes |
due |
T12458 |
29114-29116 |
TO |
denotes |
to |
T12459 |
29117-29124 |
NN |
denotes |
defects |
T12460 |
29125-29127 |
IN |
denotes |
in |
T12461 |
29128-29131 |
DT |
denotes |
the |
T12462 |
29132-29141 |
NN |
denotes |
silencing |
T12463 |
29142-29151 |
NN |
denotes |
mechanism |
T12464 |
29152-29154 |
IN |
denotes |
of |
T12465 |
29155-29165 |
JJ |
denotes |
definitive |
T12466 |
29166-29180 |
NN |
denotes |
erythropoiesis |
T12467 |
29181-29185 |
WDT |
denotes |
that |
T12468 |
29186-29191 |
VB |
denotes |
takes |
T12469 |
29192-29197 |
NN |
denotes |
place |
T12470 |
29198-29200 |
IN |
denotes |
in |
T12471 |
29201-29204 |
DT |
denotes |
the |
T12472 |
29205-29210 |
NN |
denotes |
liver |
T12473 |
29211-29212 |
-LRB- |
denotes |
( |
T12474 |
29212-29218 |
NN |
denotes |
Figure |
T12475 |
29219-29220 |
CD |
denotes |
5 |
T12476 |
29220-29221 |
-RRB- |
denotes |
) |
T12477 |
29223-29228 |
VB |
denotes |
Taken |
T12478 |
29229-29237 |
RB |
denotes |
together |
T12479 |
29237-29238 |
-COMMA- |
denotes |
, |
T12480 |
29239-29244 |
DT |
denotes |
these |
T12481 |
29245-29249 |
NN |
denotes |
data |
T12482 |
29250-29261 |
VB |
denotes |
demonstrate |
T12483 |
29262-29266 |
IN |
denotes |
that |
T12484 |
29267-29271 |
NN |
denotes |
Sox6 |
T12485 |
29272-29281 |
NN |
denotes |
functions |
T12486 |
29282-29284 |
IN |
denotes |
in |
T12487 |
29285-29295 |
JJ |
denotes |
definitive |
T12488 |
29296-29310 |
NN |
denotes |
erythropoiesis |
T12489 |
29311-29313 |
TO |
denotes |
to |
T12490 |
29314-29321 |
NN |
denotes |
silence |
T12491 |
29322-29324 |
JJ |
denotes |
ɛy |
T12492 |
29325-29331 |
NN |
denotes |
globin |
T12493 |
29332-29342 |
NN |
denotes |
expression |
T12494 |
29344-29347 |
DT |
denotes |
The |
T12495 |
29348-29358 |
NN |
denotes |
expression |
T12496 |
29359-29364 |
NN |
denotes |
level |
T12497 |
29365-29367 |
IN |
denotes |
of |
T12498 |
29368-29370 |
JJ |
denotes |
ɛy |
T12499 |
29371-29377 |
NN |
denotes |
globin |
T12500 |
29378-29380 |
IN |
denotes |
in |
T12501 |
29381-29391 |
JJ |
denotes |
homozygous |
T12502 |
29392-29396 |
NN |
denotes |
Sox6 |
T12503 |
29397-29401 |
JJ |
denotes |
null |
T12504 |
29402-29406 |
NN |
denotes |
mice |
T12505 |
29407-29409 |
IN |
denotes |
at |
T12506 |
29410-29414 |
CD |
denotes |
15.5 |
T12507 |
29415-29418 |
NN |
denotes |
dpc |
T12508 |
29419-29422 |
CC |
denotes |
and |
T12509 |
29423-29427 |
CD |
denotes |
18.5 |
T12510 |
29428-29431 |
NN |
denotes |
dpc |
T12511 |
29432-29434 |
VB |
denotes |
is |
T12512 |
29435-29448 |
RB |
denotes |
statistically |
T12513 |
29449-29459 |
JJ |
denotes |
equivalent |
T12514 |
29460-29462 |
TO |
denotes |
to |
T12515 |
29463-29466 |
DT |
denotes |
the |
T12516 |
29467-29472 |
NN |
denotes |
level |
T12517 |
29473-29475 |
IN |
denotes |
of |
T12518 |
29476-29484 |
NN |
denotes |
βmaj/min |
T12519 |
29485-29495 |
NN |
denotes |
expression |
T12520 |
29496-29498 |
IN |
denotes |
in |
T12521 |
29499-29502 |
DT |
denotes |
the |
T12522 |
29503-29509 |
NN |
denotes |
livers |
T12523 |
29510-29512 |
IN |
denotes |
of |
T12524 |
29513-29521 |
NN |
denotes |
15.5-dpc |
T12525 |
29522-29525 |
CC |
denotes |
and |
T12526 |
29526-29534 |
JJ |
denotes |
18.5-dpc |
T12527 |
29535-29545 |
JJ |
denotes |
homozygous |
T12528 |
29546-29548 |
JJ |
denotes |
WT |
T12529 |
29549-29553 |
NN |
denotes |
mice |
T12530 |
29554-29555 |
-LRB- |
denotes |
( |
T12531 |
29555-29561 |
NN |
denotes |
Figure |
T12532 |
29562-29563 |
CD |
denotes |
1 |
T12533 |
29563-29564 |
-RRB- |
denotes |
) |
T12534 |
29566-29570 |
DT |
denotes |
This |
T12535 |
29571-29583 |
VB |
denotes |
demonstrates |
T12536 |
29584-29588 |
IN |
denotes |
that |
T12537 |
29589-29596 |
JJ |
denotes |
ectopic |
T12538 |
29597-29607 |
NN |
denotes |
expression |
T12539 |
29608-29610 |
IN |
denotes |
of |
T12540 |
29611-29614 |
DT |
denotes |
the |
T12541 |
29615-29617 |
JJ |
denotes |
ɛy |
T12542 |
29618-29624 |
NN |
denotes |
globin |
T12543 |
29625-29629 |
NN |
denotes |
gene |
T12544 |
29630-29632 |
VB |
denotes |
is |
T12545 |
29633-29638 |
RB |
denotes |
quite |
T12546 |
29639-29645 |
JJ |
denotes |
robust |
T12547 |
29646-29648 |
IN |
denotes |
in |
T12548 |
29649-29659 |
JJ |
denotes |
homozygous |
T12549 |
29660-29666 |
JJ |
denotes |
mutant |
T12550 |
29667-29671 |
NN |
denotes |
mice |
T12551 |
29673-29676 |
DT |
denotes |
The |
T12552 |
29677-29687 |
NN |
denotes |
expression |
T12553 |
29688-29694 |
NN |
denotes |
levels |
T12554 |
29695-29697 |
IN |
denotes |
of |
T12555 |
29698-29701 |
CD |
denotes |
two |
T12556 |
29702-29707 |
JJ |
denotes |
other |
T12557 |
29708-29717 |
JJ |
denotes |
embryonic |
T12558 |
29718-29724 |
NN |
denotes |
globin |
T12559 |
29725-29730 |
NN |
denotes |
genes |
T12560 |
29731-29732 |
-LRB- |
denotes |
( |
T12561 |
29732-29733 |
NN |
denotes |
ζ |
T12562 |
29734-29737 |
CC |
denotes |
and |
T12563 |
29738-29741 |
NN |
denotes |
βh1 |
T12564 |
29741-29742 |
-RRB- |
denotes |
) |
T12565 |
29743-29746 |
VB |
denotes |
are |
T12566 |
29747-29751 |
RB |
denotes |
also |
T12567 |
29752-29758 |
JJ |
denotes |
higher |
T12568 |
29759-29761 |
IN |
denotes |
in |
T12569 |
29762-29767 |
NN |
denotes |
p100H |
T12570 |
29768-29779 |
NN |
denotes |
homozygotes |
T12571 |
29779-29780 |
-COMMA- |
denotes |
, |
T12572 |
29781-29789 |
VB |
denotes |
compared |
T12573 |
29790-29794 |
IN |
denotes |
with |
T12574 |
29795-29797 |
NN |
denotes |
WT |
T12575 |
29799-29803 |
IN |
denotes |
Like |
T12576 |
29804-29806 |
NN |
denotes |
ɛy |
T12577 |
29806-29807 |
-COMMA- |
denotes |
, |
T12578 |
29808-29814 |
NN |
denotes |
levels |
T12579 |
29815-29817 |
IN |
denotes |
of |
T12580 |
29818-29819 |
NN |
denotes |
ζ |
T12581 |
29820-29823 |
CC |
denotes |
and |
T12582 |
29824-29827 |
NN |
denotes |
βh1 |
T12583 |
29828-29831 |
VB |
denotes |
are |
T12584 |
29832-29844 |
RB |
denotes |
dramatically |
T12585 |
29845-29851 |
JJ |
denotes |
higher |
T12586 |
29852-29854 |
IN |
denotes |
in |
T12587 |
29855-29861 |
JJ |
denotes |
mutant |
T12588 |
29862-29866 |
NN |
denotes |
mice |
T12589 |
29867-29869 |
IN |
denotes |
at |
T12590 |
29870-29874 |
CD |
denotes |
15.5 |
T12591 |
29875-29878 |
NN |
denotes |
dpc |
T12592 |
29880-29887 |
RB |
denotes |
However |
T12593 |
29887-29888 |
-COMMA- |
denotes |
, |
T12594 |
29889-29895 |
IN |
denotes |
unlike |
T12595 |
29896-29898 |
JJ |
denotes |
ɛy |
T12596 |
29899-29905 |
NN |
denotes |
globin |
T12597 |
29905-29906 |
-COMMA- |
denotes |
, |
T12598 |
29907-29908 |
NN |
denotes |
ζ |
T12599 |
29909-29912 |
CC |
denotes |
and |
T12600 |
29913-29916 |
NN |
denotes |
βh1 |
T12601 |
29917-29924 |
NN |
denotes |
decline |
T12602 |
29925-29927 |
IN |
denotes |
in |
T12603 |
29928-29938 |
NN |
denotes |
expression |
T12604 |
29939-29941 |
IN |
denotes |
by |
T12605 |
29942-29945 |
NN |
denotes |
day |
T12606 |
29946-29950 |
CD |
denotes |
18.5 |
T12607 |
29951-29954 |
NN |
denotes |
dpc |
T12608 |
29955-29956 |
-LRB- |
denotes |
( |
T12609 |
29956-29962 |
NN |
denotes |
Figure |
T12610 |
29963-29964 |
CD |
denotes |
1 |
T12611 |
29964-29965 |
-RRB- |
denotes |
) |
T12612 |
29965-29966 |
-COMMA- |
denotes |
, |
T12613 |
29967-29977 |
VB |
denotes |
suggesting |
T12614 |
29978-29982 |
IN |
denotes |
that |
T12615 |
29983-29985 |
NN |
denotes |
ɛy |
T12616 |
29986-29988 |
VB |
denotes |
is |
T12617 |
29989-29998 |
VB |
denotes |
regulated |
T12618 |
29999-30010 |
RB |
denotes |
differently |
T12619 |
30011-30015 |
IN |
denotes |
than |
T12620 |
30016-30017 |
NN |
denotes |
ζ |
T12621 |
30018-30021 |
CC |
denotes |
and |
T12622 |
30022-30025 |
NN |
denotes |
βh1 |
T12623 |
30027-30029 |
PRP |
denotes |
It |
T12624 |
30030-30032 |
VB |
denotes |
is |
T12625 |
30033-30041 |
JJ |
denotes |
possible |
T12626 |
30042-30046 |
IN |
denotes |
that |
T12627 |
30047-30051 |
NN |
denotes |
Sox6 |
T12628 |
30052-30055 |
VB |
denotes |
has |
T12629 |
30056-30057 |
DT |
denotes |
a |
T12630 |
30058-30065 |
JJ |
denotes |
general |
T12631 |
30066-30072 |
NN |
denotes |
effect |
T12632 |
30073-30075 |
IN |
denotes |
on |
T12633 |
30076-30085 |
JJ |
denotes |
embryonic |
T12634 |
30086-30092 |
NN |
denotes |
globin |
T12635 |
30093-30098 |
NN |
denotes |
genes |
T12636 |
30099-30100 |
-LRB- |
denotes |
( |
T12637 |
30100-30103 |
CC |
denotes |
and |
T12638 |
30104-30115 |
NN |
denotes |
erythrocyte |
T12639 |
30116-30126 |
NN |
denotes |
maturation |
T12640 |
30126-30127 |
-RRB- |
denotes |
) |
T12641 |
30128-30130 |
IN |
denotes |
in |
T12642 |
30131-30139 |
NN |
denotes |
addition |
T12643 |
30140-30142 |
TO |
denotes |
to |
T12644 |
30143-30144 |
DT |
denotes |
a |
T12645 |
30145-30153 |
JJ |
denotes |
specific |
T12646 |
30154-30158 |
NN |
denotes |
role |
T12647 |
30159-30161 |
IN |
denotes |
in |
T12648 |
30162-30171 |
VB |
denotes |
silencing |
T12649 |
30172-30174 |
NN |
denotes |
ɛy |
T12650 |
30176-30184 |
IN |
denotes |
Although |
T12651 |
30185-30189 |
JJ |
denotes |
most |
T12652 |
30190-30195 |
NN |
denotes |
p100H |
T12653 |
30196-30202 |
JJ |
denotes |
mutant |
T12654 |
30203-30207 |
NN |
denotes |
mice |
T12655 |
30208-30211 |
VB |
denotes |
die |
T12656 |
30212-30216 |
RB |
denotes |
just |
T12657 |
30217-30222 |
IN |
denotes |
after |
T12658 |
30223-30228 |
VB |
denotes |
being |
T12659 |
30229-30233 |
VB |
denotes |
born |
T12660 |
30233-30234 |
-COMMA- |
denotes |
, |
T12661 |
30235-30236 |
DT |
denotes |
a |
T12662 |
30237-30241 |
JJ |
denotes |
rare |
T12663 |
30242-30245 |
JJ |
denotes |
few |
T12664 |
30246-30253 |
NN |
denotes |
survive |
T12665 |
30254-30260 |
RB |
denotes |
longer |
T12666 |
30262-30266 |
NN |
denotes |
None |
T12667 |
30267-30271 |
VB |
denotes |
have |
T12668 |
30272-30276 |
VB |
denotes |
been |
T12669 |
30277-30285 |
VB |
denotes |
observed |
T12670 |
30286-30288 |
TO |
denotes |
to |
T12671 |
30289-30293 |
VB |
denotes |
live |
T12672 |
30294-30300 |
JJ |
denotes |
longer |
T12673 |
30301-30305 |
IN |
denotes |
than |
T12674 |
30306-30307 |
CD |
denotes |
2 |
T12675 |
30308-30310 |
NN |
denotes |
wk |
T12676 |
30311-30316 |
IN |
denotes |
after |
T12677 |
30317-30322 |
NN |
denotes |
birth |
T12678 |
30323-30324 |
-LRB- |
denotes |
[ |
T12679 |
30324-30326 |
CD |
denotes |
14 |
T12680 |
30326-30327 |
-RRB- |
denotes |
] |
T12681 |
30329-30331 |
PRP |
denotes |
We |
T12682 |
30332-30340 |
VB |
denotes |
examined |
T12683 |
30341-30342 |
DT |
denotes |
a |
T12684 |
30343-30349 |
JJ |
denotes |
single |
T12685 |
30350-30358 |
JJ |
denotes |
archived |
T12686 |
30359-30365 |
NN |
denotes |
sample |
T12687 |
30366-30368 |
IN |
denotes |
of |
T12688 |
30369-30374 |
NN |
denotes |
liver |
T12689 |
30375-30378 |
NN |
denotes |
RNA |
T12690 |
30379-30383 |
IN |
denotes |
from |
T12691 |
30384-30385 |
DT |
denotes |
a |
T12692 |
30386-30392 |
JJ |
denotes |
mutant |
T12693 |
30393-30398 |
NN |
denotes |
mouse |
T12694 |
30399-30401 |
IN |
denotes |
on |
T12695 |
30402-30411 |
JJ |
denotes |
postnatal |
T12696 |
30412-30415 |
NN |
denotes |
day |
T12697 |
30416-30420 |
CD |
denotes |
13.5 |
T12698 |
30421-30424 |
IN |
denotes |
for |
T12699 |
30425-30431 |
NN |
denotes |
globin |
T12700 |
30432-30436 |
NN |
denotes |
gene |
T12701 |
30437-30447 |
NN |
denotes |
expression |
T12702 |
30448-30451 |
CC |
denotes |
and |
T12703 |
30452-30460 |
VB |
denotes |
detected |
T12704 |
30461-30465 |
JJ |
denotes |
high |
T12705 |
30466-30472 |
NN |
denotes |
levels |
T12706 |
30473-30475 |
IN |
denotes |
of |
T12707 |
30476-30478 |
JJ |
denotes |
ɛy |
T12708 |
30479-30485 |
NN |
denotes |
globin |
T12709 |
30486-30488 |
IN |
denotes |
in |
T12710 |
30489-30493 |
DT |
denotes |
this |
T12711 |
30494-30497 |
NN |
denotes |
RNA |
T12712 |
30498-30504 |
NN |
denotes |
sample |
T12713 |
30504-30505 |
-COMMA- |
denotes |
, |
T12714 |
30506-30514 |
VB |
denotes |
compared |
T12715 |
30515-30519 |
IN |
denotes |
with |
T12716 |
30520-30532 |
JJ |
denotes |
undetectable |
T12717 |
30533-30535 |
JJ |
denotes |
ɛy |
T12718 |
30536-30539 |
NN |
denotes |
RNA |
T12719 |
30540-30542 |
IN |
denotes |
in |
T12720 |
30543-30545 |
NN |
denotes |
WT |
T12721 |
30546-30553 |
NN |
denotes |
control |
T12722 |
30554-30558 |
NN |
denotes |
mice |
T12723 |
30560-30562 |
IN |
denotes |
At |
T12724 |
30563-30567 |
DT |
denotes |
this |
T12725 |
30568-30573 |
NN |
denotes |
point |
T12726 |
30574-30576 |
IN |
denotes |
in |
T12727 |
30577-30588 |
NN |
denotes |
development |
T12728 |
30588-30589 |
-COMMA- |
denotes |
, |
T12729 |
30590-30593 |
DT |
denotes |
the |
T12730 |
30594-30600 |
NN |
denotes |
levels |
T12731 |
30601-30603 |
IN |
denotes |
of |
T12732 |
30604-30605 |
NN |
denotes |
ζ |
T12733 |
30606-30609 |
CC |
denotes |
and |
T12734 |
30610-30613 |
NN |
denotes |
βh1 |
T12735 |
30614-30617 |
NN |
denotes |
RNA |
T12736 |
30618-30622 |
VB |
denotes |
were |
T12737 |
30623-30635 |
JJ |
denotes |
undetectable |
T12738 |
30636-30640 |
CC |
denotes |
both |
T12739 |
30641-30643 |
IN |
denotes |
in |
T12740 |
30644-30650 |
JJ |
denotes |
mutant |
T12741 |
30651-30654 |
CC |
denotes |
and |
T12742 |
30655-30657 |
NN |
denotes |
WT |
T12743 |
30657-30658 |
-COLON- |
denotes |
; |
T12744 |
30659-30666 |
RB |
denotes |
however |
T12745 |
30666-30667 |
-COMMA- |
denotes |
, |
T12746 |
30668-30673 |
JJ |
denotes |
adult |
T12747 |
30674-30680 |
JJ |
denotes |
β-like |
T12748 |
30681-30687 |
NN |
denotes |
globin |
T12749 |
30688-30691 |
NN |
denotes |
RNA |
T12750 |
30692-30698 |
NN |
denotes |
levels |
T12751 |
30699-30703 |
VB |
denotes |
were |
T12752 |
30704-30714 |
RB |
denotes |
moderately |
T12753 |
30715-30723 |
JJ |
denotes |
elevated |
T12754 |
30724-30726 |
IN |
denotes |
in |
T12755 |
30727-30730 |
DT |
denotes |
the |
T12756 |
30731-30737 |
JJ |
denotes |
mutant |
T12757 |
30738-30741 |
NN |
denotes |
RNA |
T12758 |
30742-30750 |
VB |
denotes |
compared |
T12759 |
30751-30755 |
IN |
denotes |
with |
T12760 |
30756-30758 |
NN |
denotes |
WT |
T12761 |
30759-30760 |
-LRB- |
denotes |
( |
T12762 |
30760-30771 |
JJ |
denotes |
unpublished |
T12763 |
30772-30776 |
NN |
denotes |
data |
T12764 |
30776-30777 |
-RRB- |
denotes |
) |
T12765 |
30777-30778 |
-COMMA- |
denotes |
, |
T12766 |
30779-30786 |
JJ |
denotes |
similar |
T12767 |
30787-30789 |
TO |
denotes |
to |
T12768 |
30790-30794 |
WP |
denotes |
what |
T12769 |
30795-30797 |
PRP |
denotes |
we |
T12770 |
30798-30805 |
VB |
denotes |
observe |
T12771 |
30806-30808 |
IN |
denotes |
at |
T12772 |
30809-30813 |
CD |
denotes |
18.5 |
T12773 |
30814-30817 |
NN |
denotes |
dpc |
T12774 |
30818-30819 |
-LRB- |
denotes |
( |
T12775 |
30819-30825 |
NN |
denotes |
Figure |
T12776 |
30826-30827 |
CD |
denotes |
1 |
T12777 |
30827-30828 |
-RRB- |
denotes |
) |
T12778 |
30830-30835 |
DT |
denotes |
These |
T12779 |
30836-30844 |
NN |
denotes |
findings |
T12780 |
30845-30852 |
VB |
denotes |
suggest |
T12781 |
30853-30857 |
IN |
denotes |
that |
T12782 |
30858-30862 |
NN |
denotes |
Sox6 |
T12783 |
30863-30872 |
VB |
denotes |
continues |
T12784 |
30873-30875 |
TO |
denotes |
to |
T12785 |
30876-30884 |
VB |
denotes |
function |
T12786 |
30885-30896 |
RB |
denotes |
postnatally |
T12787 |
30897-30899 |
TO |
denotes |
to |
T12788 |
30900-30907 |
NN |
denotes |
silence |
T12789 |
30908-30910 |
JJ |
denotes |
ɛy |
T12790 |
30911-30917 |
NN |
denotes |
globin |
T12791 |
30918-30928 |
NN |
denotes |
expression |
T12792 |
30929-30932 |
CC |
denotes |
and |
T12793 |
30933-30936 |
VB |
denotes |
has |
T12794 |
30937-30938 |
DT |
denotes |
a |
T12795 |
30939-30945 |
JJ |
denotes |
unique |
T12796 |
30946-30954 |
NN |
denotes |
function |
T12797 |
30955-30957 |
IN |
denotes |
in |
T12798 |
30958-30961 |
DT |
denotes |
the |
T12799 |
30962-30972 |
NN |
denotes |
regulation |
T12800 |
30973-30975 |
IN |
denotes |
of |
T12801 |
30976-30985 |
NN |
denotes |
ɛy-globin |
T12802 |
30987-30990 |
DT |
denotes |
The |
T12803 |
30991-31000 |
NN |
denotes |
mechanism |
T12804 |
31001-31003 |
IN |
denotes |
by |
T12805 |
31004-31009 |
WDT |
denotes |
which |
T12806 |
31010-31014 |
NN |
denotes |
Sox6 |
T12807 |
31015-31024 |
VB |
denotes |
regulates |
T12808 |
31025-31028 |
DT |
denotes |
the |
T12809 |
31029-31034 |
JJ |
denotes |
other |
T12810 |
31035-31044 |
JJ |
denotes |
embryonic |
T12811 |
31045-31051 |
NN |
denotes |
globin |
T12812 |
31052-31057 |
NN |
denotes |
genes |
T12813 |
31058-31065 |
VB |
denotes |
remains |
T12814 |
31066-31068 |
TO |
denotes |
to |
T12815 |
31069-31071 |
VB |
denotes |
be |
T12816 |
31072-31082 |
VB |
denotes |
elucidated |
T12817 |
31084-31088 |
NN |
denotes |
Sox6 |
T12818 |
31089-31092 |
VB |
denotes |
has |
T12819 |
31093-31098 |
JJ |
denotes |
other |
T12820 |
31099-31106 |
NN |
denotes |
effects |
T12821 |
31107-31109 |
IN |
denotes |
in |
T12822 |
31110-31124 |
NN |
denotes |
erythropoiesis |
T12823 |
31124-31125 |
-COMMA- |
denotes |
, |
T12824 |
31126-31135 |
VB |
denotes |
including |
T12825 |
31136-31137 |
DT |
denotes |
a |
T12826 |
31138-31143 |
NN |
denotes |
delay |
T12827 |
31144-31146 |
IN |
denotes |
in |
T12828 |
31147-31169 |
NN |
denotes |
enucleation/maturation |
T12829 |
31170-31172 |
IN |
denotes |
in |
T12830 |
31173-31178 |
NN |
denotes |
p100H |
T12831 |
31179-31185 |
JJ |
denotes |
mutant |
T12832 |
31186-31190 |
NN |
denotes |
mice |
T12833 |
31192-31196 |
DT |
denotes |
This |
T12834 |
31197-31200 |
MD |
denotes |
may |
T12835 |
31201-31203 |
VB |
denotes |
be |
T12836 |
31204-31207 |
DT |
denotes |
the |
T12837 |
31208-31214 |
NN |
denotes |
result |
T12838 |
31215-31217 |
IN |
denotes |
of |
T12839 |
31218-31226 |
JJ |
denotes |
indirect |
T12840 |
31227-31234 |
NN |
denotes |
effects |
T12841 |
31234-31235 |
-COMMA- |
denotes |
, |
T12842 |
31236-31240 |
JJ |
denotes |
such |
T12843 |
31241-31243 |
IN |
denotes |
as |
T12844 |
31244-31258 |
JJ |
denotes |
stress-induced |
T12845 |
31259-31272 |
NN |
denotes |
proliferation |
T12846 |
31273-31274 |
-LRB- |
denotes |
( |
T12847 |
31274-31283 |
VB |
denotes |
resulting |
T12848 |
31284-31288 |
IN |
denotes |
from |
T12849 |
31289-31296 |
JJ |
denotes |
cardiac |
T12850 |
31297-31304 |
NN |
denotes |
defects |
T12851 |
31304-31305 |
-RRB- |
denotes |
) |
T12852 |
31306-31312 |
CC |
denotes |
and/or |
T12853 |
31313-31319 |
NN |
denotes |
anemia |
T12854 |
31321-31327 |
JJ |
denotes |
Severe |
T12855 |
31328-31334 |
NN |
denotes |
anemia |
T12856 |
31335-31338 |
MD |
denotes |
can |
T12857 |
31339-31343 |
VB |
denotes |
lead |
T12858 |
31344-31346 |
TO |
denotes |
to |
T12859 |
31347-31352 |
JJ |
denotes |
rapid |
T12860 |
31353-31362 |
JJ |
denotes |
premature |
T12861 |
31363-31370 |
NN |
denotes |
release |
T12862 |
31371-31373 |
IN |
denotes |
of |
T12863 |
31374-31377 |
JJ |
denotes |
red |
T12864 |
31378-31383 |
NN |
denotes |
cells |
T12865 |
31383-31384 |
-COMMA- |
denotes |
, |
T12866 |
31385-31390 |
JJ |
denotes |
prior |
T12867 |
31391-31393 |
TO |
denotes |
to |
T12868 |
31394-31399 |
PRP-DOLLAR- |
denotes |
their |
T12869 |
31400-31408 |
JJ |
denotes |
complete |
T12870 |
31409-31419 |
NN |
denotes |
maturation |
T12871 |
31421-31428 |
RB |
denotes |
However |
T12872 |
31428-31429 |
-COMMA- |
denotes |
, |
T12873 |
31430-31433 |
DT |
denotes |
the |
T12874 |
31434-31444 |
NN |
denotes |
hematocrit |
T12875 |
31445-31447 |
IN |
denotes |
of |
T12876 |
31448-31456 |
JJ |
denotes |
18.5-dpc |
T12877 |
31457-31463 |
JJ |
denotes |
mutant |
T12878 |
31464-31468 |
NN |
denotes |
mice |
T12879 |
31469-31471 |
VB |
denotes |
is |
T12880 |
31472-31476 |
RB |
denotes |
only |
T12881 |
31477-31479 |
CD |
denotes |
20 |
T12882 |
31479-31480 |
NN |
denotes |
% |
T12883 |
31481-31486 |
JJ |
denotes |
lower |
T12884 |
31487-31491 |
IN |
denotes |
than |
T12885 |
31492-31496 |
DT |
denotes |
that |
T12886 |
31497-31499 |
IN |
denotes |
of |
T12887 |
31500-31502 |
NN |
denotes |
WT |
T12888 |
31503-31504 |
-LRB- |
denotes |
( |
T12889 |
31504-31515 |
JJ |
denotes |
unpublished |
T12890 |
31516-31520 |
NN |
denotes |
data |
T12891 |
31520-31521 |
-RRB- |
denotes |
) |
T12892 |
31521-31522 |
-COMMA- |
denotes |
, |
T12893 |
31523-31526 |
CC |
denotes |
and |
T12894 |
31527-31531 |
DT |
denotes |
this |
T12895 |
31532-31536 |
JJ |
denotes |
mild |
T12896 |
31537-31543 |
NN |
denotes |
anemia |
T12897 |
31544-31546 |
VB |
denotes |
is |
T12898 |
31547-31555 |
RB |
denotes |
probably |
T12899 |
31556-31559 |
RB |
denotes |
not |
T12900 |
31560-31570 |
JJ |
denotes |
sufficient |
T12901 |
31571-31573 |
TO |
denotes |
to |
T12902 |
31574-31581 |
VB |
denotes |
explain |
T12903 |
31582-31585 |
DT |
denotes |
the |
T12904 |
31586-31592 |
NN |
denotes |
extent |
T12905 |
31593-31595 |
IN |
denotes |
of |
T12906 |
31596-31605 |
JJ |
denotes |
nucleated |
T12907 |
31606-31609 |
JJ |
denotes |
red |
T12908 |
31610-31615 |
NN |
denotes |
cells |
T12909 |
31617-31630 |
RB |
denotes |
Alternatively |
T12910 |
31630-31631 |
-COMMA- |
denotes |
, |
T12911 |
31632-31636 |
NN |
denotes |
Sox6 |
T12912 |
31637-31643 |
PRP |
denotes |
itself |
T12913 |
31644-31647 |
MD |
denotes |
may |
T12914 |
31648-31652 |
VB |
denotes |
play |
T12915 |
31653-31654 |
DT |
denotes |
a |
T12916 |
31655-31659 |
NN |
denotes |
role |
T12917 |
31660-31662 |
IN |
denotes |
in |
T12918 |
31663-31666 |
JJ |
denotes |
red |
T12919 |
31667-31671 |
NN |
denotes |
cell |
T12920 |
31672-31680 |
JJ |
denotes |
terminal |
T12921 |
31681-31696 |
NN |
denotes |
differentiation |
T12922 |
31696-31697 |
-COMMA- |
denotes |
, |
T12923 |
31698-31700 |
IN |
denotes |
as |
T12924 |
31701-31703 |
PRP |
denotes |
it |
T12925 |
31704-31707 |
VB |
denotes |
has |
T12926 |
31708-31712 |
VB |
denotes |
been |
T12927 |
31713-31718 |
VB |
denotes |
shown |
T12928 |
31719-31721 |
TO |
denotes |
to |
T12929 |
31722-31724 |
VB |
denotes |
be |
T12930 |
31725-31727 |
DT |
denotes |
an |
T12931 |
31728-31737 |
JJ |
denotes |
important |
T12932 |
31738-31744 |
NN |
denotes |
factor |
T12933 |
31745-31747 |
IN |
denotes |
in |
T12934 |
31748-31755 |
JJ |
denotes |
cardiac |
T12935 |
31756-31757 |
-LRB- |
denotes |
[ |
T12936 |
31757-31759 |
CD |
denotes |
15 |
T12937 |
31759-31760 |
-RRB- |
denotes |
] |
T12938 |
31760-31761 |
-COMMA- |
denotes |
, |
T12939 |
31762-31770 |
JJ |
denotes |
neuronal |
T12940 |
31771-31772 |
-LRB- |
denotes |
[ |
T12941 |
31772-31774 |
CD |
denotes |
10 |
T12942 |
31774-31775 |
-RRB- |
denotes |
] |
T12943 |
31775-31776 |
-COMMA- |
denotes |
, |
T12944 |
31777-31787 |
JJ |
denotes |
astrocytic |
T12945 |
31788-31789 |
-LRB- |
denotes |
[ |
T12946 |
31789-31791 |
CD |
denotes |
11 |
T12947 |
31791-31792 |
-RRB- |
denotes |
] |
T12948 |
31792-31793 |
-COMMA- |
denotes |
, |
T12949 |
31794-31797 |
CC |
denotes |
and |
T12950 |
31798-31807 |
NN |
denotes |
cartilage |
T12951 |
31808-31823 |
NN |
denotes |
differentiation |
T12952 |
31824-31832 |
NN |
denotes |
programs |
T12953 |
31833-31834 |
-LRB- |
denotes |
[ |
T12954 |
31834-31842 |
CD |
denotes |
32,41–44 |
T12955 |
31842-31843 |
-RRB- |
denotes |
] |
T12956 |
31845-31848 |
DT |
denotes |
The |
T12957 |
31849-31860 |
NN |
denotes |
restoration |
T12958 |
31861-31863 |
IN |
denotes |
of |
T12959 |
31864-31870 |
JJ |
denotes |
normal |
T12960 |
31871-31882 |
NN |
denotes |
enucleation |
T12961 |
31883-31885 |
IN |
denotes |
of |
T12962 |
31886-31889 |
JJ |
denotes |
red |
T12963 |
31890-31895 |
NN |
denotes |
cells |
T12964 |
31896-31898 |
IN |
denotes |
in |
T12965 |
31899-31913 |
JJ |
denotes |
Sox6-deficient |
T12966 |
31914-31919 |
NN |
denotes |
mouse |
T12967 |
31920-31922 |
IN |
denotes |
by |
T12968 |
31923-31932 |
JJ |
denotes |
postnatal |
T12969 |
31933-31936 |
NN |
denotes |
day |
T12970 |
31937-31941 |
CD |
denotes |
10.5 |
T12971 |
31942-31945 |
MD |
denotes |
may |
T12972 |
31946-31952 |
VB |
denotes |
result |
T12973 |
31953-31957 |
IN |
denotes |
from |
T12974 |
31958-31968 |
JJ |
denotes |
functional |
T12975 |
31969-31981 |
NN |
denotes |
compensation |
T12976 |
31982-31984 |
IN |
denotes |
of |
T12977 |
31985-31990 |
JJ |
denotes |
other |
T12978 |
31991-31994 |
NN |
denotes |
Sox |
T12979 |
31995-32003 |
NN |
denotes |
proteins |
T12980 |
32004-32005 |
-LRB- |
denotes |
( |
T12981 |
32005-32014 |
VB |
denotes |
expressed |
T12982 |
32015-32017 |
IN |
denotes |
at |
T12983 |
32018-32023 |
JJ |
denotes |
later |
T12984 |
32024-32037 |
JJ |
denotes |
developmental |
T12985 |
32038-32044 |
NN |
denotes |
stages |
T12986 |
32044-32045 |
-RRB- |
denotes |
) |
T12987 |
32045-32046 |
-COMMA- |
denotes |
, |
T12988 |
32047-32052 |
IN |
denotes |
since |
T12989 |
32053-32063 |
JJ |
denotes |
functional |
T12990 |
32064-32074 |
NN |
denotes |
redundancy |
T12991 |
32075-32077 |
VB |
denotes |
is |
T12992 |
32078-32079 |
DT |
denotes |
a |
T12993 |
32080-32089 |
VB |
denotes |
recurring |
T12994 |
32090-32095 |
NN |
denotes |
theme |
T12995 |
32096-32100 |
IN |
denotes |
with |
T12996 |
32101-32104 |
NN |
denotes |
Sox |
T12997 |
32105-32113 |
NN |
denotes |
proteins |
T12998 |
32114-32115 |
-LRB- |
denotes |
[ |
T12999 |
32115-32123 |
CD |
denotes |
13,45,46 |
T13000 |
32123-32124 |
-RRB- |
denotes |
] |
T13001 |
32126-32134 |
RB |
denotes |
Moreover |
T13002 |
32134-32135 |
-COMMA- |
denotes |
, |
T13003 |
32136-32150 |
NN |
denotes |
erythropoiesis |
T13004 |
32151-32154 |
VB |
denotes |
has |
T13005 |
32155-32162 |
RB |
denotes |
already |
T13006 |
32163-32170 |
VB |
denotes |
shifted |
T13007 |
32171-32175 |
IN |
denotes |
from |
T13008 |
32176-32181 |
JJ |
denotes |
fetal |
T13009 |
32182-32187 |
NN |
denotes |
liver |
T13010 |
32188-32190 |
TO |
denotes |
to |
T13011 |
32191-32195 |
NN |
denotes |
bone |
T13012 |
32196-32202 |
NN |
denotes |
marrow |
T13013 |
32203-32205 |
IN |
denotes |
by |
T13014 |
32206-32215 |
JJ |
denotes |
postnatal |
T13015 |
32216-32219 |
NN |
denotes |
day |
T13016 |
32220-32224 |
CD |
denotes |
10.5 |
T13017 |
32226-32229 |
DT |
denotes |
The |
T13018 |
32230-32242 |
VB |
denotes |
accompanying |
T13019 |
32243-32249 |
NN |
denotes |
change |
T13020 |
32250-32252 |
IN |
denotes |
in |
T13021 |
32253-32256 |
DT |
denotes |
the |
T13022 |
32257-32273 |
NN |
denotes |
microenvironment |
T13023 |
32274-32276 |
IN |
denotes |
of |
T13024 |
32277-32280 |
JJ |
denotes |
red |
T13025 |
32281-32285 |
NN |
denotes |
cell |
T13026 |
32286-32296 |
NN |
denotes |
production |
T13027 |
32297-32300 |
MD |
denotes |
may |
T13028 |
32301-32307 |
VB |
denotes |
permit |
T13029 |
32308-32314 |
JJ |
denotes |
normal |
T13030 |
32315-32326 |
NN |
denotes |
enucleation |
T13031 |
32328-32342 |
NN |
denotes |
Identification |
T13032 |
32343-32345 |
IN |
denotes |
of |
T13033 |
32346-32350 |
NN |
denotes |
Sox6 |
T13034 |
32351-32361 |
JJ |
denotes |
downstream |
T13035 |
32362-32368 |
NN |
denotes |
target |
T13036 |
32369-32374 |
NN |
denotes |
genes |
T13037 |
32375-32378 |
CC |
denotes |
and |
T13038 |
32379-32382 |
PRP-DOLLAR- |
denotes |
its |
T13039 |
32383-32394 |
VB |
denotes |
interacting |
T13040 |
32395-32403 |
NN |
denotes |
proteins |
T13041 |
32404-32408 |
MD |
denotes |
will |
T13042 |
32409-32413 |
VB |
denotes |
shed |
T13043 |
32414-32419 |
NN |
denotes |
light |
T13044 |
32420-32422 |
IN |
denotes |
on |
T13045 |
32423-32426 |
DT |
denotes |
the |
T13046 |
32427-32431 |
NN |
denotes |
role |
T13047 |
32432-32434 |
IN |
denotes |
of |
T13048 |
32435-32439 |
NN |
denotes |
Sox6 |
T13049 |
32440-32442 |
IN |
denotes |
in |
T13050 |
32443-32446 |
JJ |
denotes |
red |
T13051 |
32447-32451 |
NN |
denotes |
cell |
T13052 |
32452-32460 |
JJ |
denotes |
terminal |
T13053 |
32461-32476 |
NN |
denotes |
differentiation |
T13054 |
32477-32480 |
CC |
denotes |
and |
T13055 |
32481-32484 |
DT |
denotes |
the |
T13056 |
32485-32496 |
NN |
denotes |
enucleation |
T13057 |
32497-32504 |
NN |
denotes |
process |
T13058 |
32506-32514 |
RB |
denotes |
Recently |
T13059 |
32514-32515 |
-COMMA- |
denotes |
, |
T13060 |
32516-32518 |
FW |
denotes |
in |
T13061 |
32519-32523 |
FW |
denotes |
vivo |
T13062 |
32524-32527 |
CC |
denotes |
and |
T13063 |
32528-32530 |
FW |
denotes |
in |
T13064 |
32531-32536 |
FW |
denotes |
vitro |
T13065 |
32537-32545 |
NN |
denotes |
analyses |
T13066 |
32546-32553 |
VB |
denotes |
suggest |
T13067 |
32554-32558 |
IN |
denotes |
that |
T13068 |
32559-32571 |
NN |
denotes |
reactivation |
T13069 |
32572-32574 |
IN |
denotes |
of |
T13070 |
32575-32580 |
JJ |
denotes |
human |
T13071 |
32581-32589 |
NN |
denotes |
ɛ-globin |
T13072 |
32590-32595 |
MD |
denotes |
would |
T13073 |
32596-32598 |
VB |
denotes |
be |
T13074 |
32599-32614 |
RB |
denotes |
therapeutically |
T13075 |
32615-32625 |
JJ |
denotes |
beneficial |
T13076 |
32626-32628 |
TO |
denotes |
to |
T13077 |
32629-32635 |
NN |
denotes |
adults |
T13078 |
32636-32640 |
IN |
denotes |
with |
T13079 |
32641-32647 |
NN |
denotes |
sickle |
T13080 |
32648-32652 |
NN |
denotes |
cell |
T13081 |
32653-32660 |
NN |
denotes |
disease |
T13082 |
32661-32662 |
-LRB- |
denotes |
[ |
T13083 |
32662-32664 |
CD |
denotes |
47 |
T13084 |
32664-32665 |
-RRB- |
denotes |
] |
T13085 |
32665-32666 |
-COMMA- |
denotes |
, |
T13086 |
32667-32676 |
VB |
denotes |
providing |
T13087 |
32677-32678 |
DT |
denotes |
a |
T13088 |
32679-32688 |
NN |
denotes |
rationale |
T13089 |
32689-32692 |
IN |
denotes |
for |
T13090 |
32693-32701 |
JJ |
denotes |
detailed |
T13091 |
32702-32716 |
NN |
denotes |
investigations |
T13092 |
32717-32721 |
IN |
denotes |
into |
T13093 |
32722-32725 |
DT |
denotes |
the |
T13094 |
32726-32735 |
JJ |
denotes |
molecular |
T13095 |
32736-32741 |
NN |
denotes |
basis |
T13096 |
32742-32744 |
IN |
denotes |
of |
T13097 |
32745-32753 |
JJ |
denotes |
ɛ-globin |
T13098 |
32754-32758 |
NN |
denotes |
gene |
T13099 |
32759-32768 |
NN |
denotes |
silencing |
T13100 |
32770-32773 |
DT |
denotes |
The |
T13101 |
32774-32781 |
JJ |
denotes |
present |
T13102 |
32782-32787 |
NN |
denotes |
study |
T13103 |
32788-32798 |
VB |
denotes |
identifies |
T13104 |
32799-32800 |
DT |
denotes |
a |
T13105 |
32801-32806 |
JJ |
denotes |
novel |
T13106 |
32807-32816 |
NN |
denotes |
repressor |
T13107 |
32816-32817 |
-COMMA- |
denotes |
, |
T13108 |
32818-32822 |
NN |
denotes |
Sox6 |
T13109 |
32822-32823 |
-COMMA- |
denotes |
, |
T13110 |
32824-32829 |
WDT |
denotes |
which |
T13111 |
32830-32835 |
VB |
denotes |
binds |
T13112 |
32836-32838 |
TO |
denotes |
to |
T13113 |
32839-32842 |
DT |
denotes |
the |
T13114 |
32843-32845 |
JJ |
denotes |
ɛy |
T13115 |
32846-32854 |
JJ |
denotes |
proximal |
T13116 |
32855-32863 |
NN |
denotes |
promoter |
T13117 |
32863-32864 |
-COMMA- |
denotes |
, |
T13118 |
32865-32876 |
RB |
denotes |
potentially |
T13119 |
32877-32879 |
IN |
denotes |
as |
T13120 |
32880-32884 |
NN |
denotes |
part |
T13121 |
32885-32887 |
IN |
denotes |
of |
T13122 |
32888-32889 |
DT |
denotes |
a |
T13123 |
32890-32896 |
JJ |
denotes |
larger |
T13124 |
32897-32907 |
NN |
denotes |
repression |
T13125 |
32908-32915 |
NN |
denotes |
complex |
T13126 |
32917-32924 |
IN |
denotes |
Because |
T13127 |
32925-32931 |
JJ |
denotes |
murine |
T13128 |
32932-32936 |
NN |
denotes |
Sox6 |
T13129 |
32937-32940 |
CC |
denotes |
and |
T13130 |
32941-32944 |
PRP-DOLLAR- |
denotes |
its |
T13131 |
32945-32950 |
JJ |
denotes |
human |
T13132 |
32951-32962 |
NN |
denotes |
counterpart |
T13133 |
32963-32966 |
VB |
denotes |
are |
T13134 |
32967-32969 |
CD |
denotes |
94 |
T13135 |
32969-32970 |
NN |
denotes |
% |
T13136 |
32971-32980 |
JJ |
denotes |
identical |
T13137 |
32981-32983 |
IN |
denotes |
at |
T13138 |
32984-32987 |
DT |
denotes |
the |
T13139 |
32988-32993 |
JJ |
denotes |
amino |
T13140 |
32994-32998 |
NN |
denotes |
acid |
T13141 |
32999-33004 |
NN |
denotes |
level |
T13142 |
33005-33006 |
-LRB- |
denotes |
[ |
T13143 |
33006-33008 |
CD |
denotes |
48 |
T13144 |
33008-33009 |
-RRB- |
denotes |
] |
T13145 |
33009-33010 |
-COMMA- |
denotes |
, |
T13146 |
33011-33013 |
PRP |
denotes |
it |
T13147 |
33014-33016 |
VB |
denotes |
is |
T13148 |
33017-33025 |
JJ |
denotes |
possible |
T13149 |
33026-33030 |
IN |
denotes |
that |
T13150 |
33031-33036 |
JJ |
denotes |
human |
T13151 |
33037-33041 |
NN |
denotes |
Sox6 |
T13152 |
33042-33045 |
MD |
denotes |
may |
T13153 |
33046-33050 |
RB |
denotes |
also |
T13154 |
33051-33053 |
VB |
denotes |
be |
T13155 |
33054-33063 |
JJ |
denotes |
important |
T13156 |
33064-33066 |
IN |
denotes |
in |
T13157 |
33067-33072 |
JJ |
denotes |
human |
T13158 |
33073-33074 |
NN |
denotes |
ɛ |
T13159 |
33075-33081 |
NN |
denotes |
globin |
T13160 |
33082-33091 |
NN |
denotes |
silencing |
T13161 |
33093-33098 |
EX |
denotes |
There |
T13162 |
33099-33101 |
VB |
denotes |
is |
T13163 |
33102-33113 |
JJ |
denotes |
significant |
T13164 |
33114-33122 |
NN |
denotes |
sequence |
T13165 |
33123-33131 |
NN |
denotes |
homology |
T13166 |
33132-33139 |
IN |
denotes |
between |
T13167 |
33140-33143 |
DT |
denotes |
the |
T13168 |
33144-33149 |
JJ |
denotes |
human |
T13169 |
33150-33153 |
CC |
denotes |
and |
T13170 |
33154-33159 |
NN |
denotes |
mouse |
T13171 |
33160-33161 |
NN |
denotes |
ɛ |
T13172 |
33162-33170 |
NN |
denotes |
promoter |
T13173 |
33171-33178 |
NN |
denotes |
regions |
T13174 |
33178-33179 |
-COMMA- |
denotes |
, |
T13175 |
33180-33183 |
CC |
denotes |
and |
T13176 |
33184-33187 |
DT |
denotes |
the |
T13177 |
33188-33193 |
JJ |
denotes |
human |
T13178 |
33194-33202 |
NN |
denotes |
promoter |
T13179 |
33203-33211 |
VB |
denotes |
contains |
T13180 |
33212-33214 |
IN |
denotes |
at |
T13181 |
33215-33220 |
JJ |
denotes |
least |
T13182 |
33221-33224 |
CD |
denotes |
two |
T13183 |
33225-33234 |
JJ |
denotes |
potential |
T13184 |
33235-33239 |
NN |
denotes |
Sox6 |
T13185 |
33240-33247 |
NN |
denotes |
binding |
T13186 |
33248-33253 |
NN |
denotes |
sites |
T13187 |
33255-33261 |
RB |
denotes |
Indeed |
T13188 |
33261-33262 |
-COMMA- |
denotes |
, |
T13189 |
33263-33266 |
DT |
denotes |
the |
T13190 |
33267-33276 |
NN |
denotes |
existence |
T13191 |
33277-33279 |
IN |
denotes |
of |
T13192 |
33280-33281 |
DT |
denotes |
a |
T13193 |
33282-33290 |
NN |
denotes |
silencer |
T13194 |
33291-33293 |
IN |
denotes |
of |
T13195 |
33294-33297 |
DT |
denotes |
the |
T13196 |
33298-33303 |
JJ |
denotes |
human |
T13197 |
33304-33305 |
NN |
denotes |
ɛ |
T13198 |
33306-33312 |
NN |
denotes |
globin |
T13199 |
33313-33317 |
NN |
denotes |
gene |
T13200 |
33318-33321 |
VB |
denotes |
has |
T13201 |
33322-33326 |
VB |
denotes |
been |
T13202 |
33327-33335 |
VB |
denotes |
proposed |
T13203 |
33336-33337 |
-LRB- |
denotes |
[ |
T13204 |
33337-33342 |
CD |
denotes |
49,50 |
T13205 |
33342-33343 |
-RRB- |
denotes |
] |
T13206 |
33345-33349 |
RB |
denotes |
Thus |
T13207 |
33349-33350 |
-COMMA- |
denotes |
, |
T13208 |
33351-33362 |
NN |
denotes |
elucidation |
T13209 |
33363-33365 |
IN |
denotes |
of |
T13210 |
33366-33369 |
DT |
denotes |
the |
T13211 |
33370-33374 |
NN |
denotes |
Sox6 |
T13212 |
33375-33385 |
NN |
denotes |
repression |
T13213 |
33386-33395 |
NN |
denotes |
mechanism |
T13214 |
33396-33399 |
CC |
denotes |
and |
T13215 |
33400-33414 |
NN |
denotes |
identification |
T13216 |
33415-33417 |
IN |
denotes |
of |
T13217 |
33418-33423 |
JJ |
denotes |
other |
T13218 |
33424-33434 |
NN |
denotes |
components |
T13219 |
33435-33437 |
IN |
denotes |
of |
T13220 |
33438-33441 |
DT |
denotes |
the |
T13221 |
33442-33457 |
JJ |
denotes |
Sox6-containing |
T13222 |
33458-33465 |
NN |
denotes |
complex |
T13223 |
33466-33469 |
MD |
denotes |
may |
T13224 |
33470-33477 |
VB |
denotes |
further |
T13225 |
33478-33481 |
PRP-DOLLAR- |
denotes |
our |
T13226 |
33482-33495 |
NN |
denotes |
understanding |
T13227 |
33496-33498 |
IN |
denotes |
of |
T13228 |
33499-33500 |
NN |
denotes |
ɛ |
T13229 |
33501-33507 |
NN |
denotes |
globin |
T13230 |
33508-33518 |
NN |
denotes |
regulation |
T13231 |
33519-33522 |
CC |
denotes |
and |
T13232 |
33523-33534 |
RB |
denotes |
potentially |
T13233 |
33535-33541 |
VB |
denotes |
reveal |
T13234 |
33542-33552 |
JJ |
denotes |
additional |
T13235 |
33553-33562 |
JJ |
denotes |
molecular |
T13236 |
33563-33570 |
NN |
denotes |
targets |
T13237 |
33571-33574 |
IN |
denotes |
for |
T13238 |
33575-33578 |
DT |
denotes |
the |
T13239 |
33579-33588 |
NN |
denotes |
treatment |
T13240 |
33589-33591 |
IN |
denotes |
of |
T13241 |
33592-33598 |
JJ |
denotes |
sickle |
T13242 |
33599-33603 |
NN |
denotes |
cell |
T13243 |
33604-33610 |
NN |
denotes |
anemia |
T13244 |
33611-33614 |
CC |
denotes |
and |
T13245 |
33615-33616 |
VB |
denotes |
β |
T13246 |
33617-33629 |
NN |
denotes |
thalassemias |
T16073 |
33655-33662 |
NN |
denotes |
Plasmid |
T16074 |
33663-33675 |
NN |
denotes |
construction |
T16075 |
33677-33680 |
DT |
denotes |
The |
T16076 |
33681-33683 |
JJ |
denotes |
ɛy |
T16077 |
33684-33692 |
NN |
denotes |
promoter |
T16078 |
33693-33701 |
NN |
denotes |
deletion |
T16079 |
33702-33710 |
NN |
denotes |
reporter |
T16080 |
33711-33718 |
NN |
denotes |
plasmid |
T16081 |
33719-33720 |
-LRB- |
denotes |
( |
T16082 |
33720-33725 |
NN |
denotes |
E-luc |
T16083 |
33725-33726 |
-RRB- |
denotes |
) |
T16084 |
33727-33730 |
VB |
denotes |
was |
T16085 |
33731-33740 |
VB |
denotes |
generated |
T16086 |
33741-33743 |
IN |
denotes |
by |
T16087 |
33744-33747 |
NN |
denotes |
PCR |
T16088 |
33748-33761 |
NN |
denotes |
amplification |
T16089 |
33762-33764 |
IN |
denotes |
of |
T16090 |
33765-33768 |
DT |
denotes |
the |
T16091 |
33769-33771 |
JJ |
denotes |
ɛy |
T16092 |
33772-33780 |
JJ |
denotes |
proximal |
T16093 |
33781-33789 |
NN |
denotes |
promoter |
T16094 |
33791-33792 |
DT |
denotes |
A |
T16095 |
33793-33799 |
JJ |
denotes |
2.2-kb |
T16096 |
33800-33808 |
NN |
denotes |
fragment |
T16097 |
33809-33817 |
RB |
denotes |
upstream |
T16098 |
33818-33820 |
IN |
denotes |
of |
T16099 |
33821-33824 |
DT |
denotes |
the |
T16100 |
33825-33827 |
JJ |
denotes |
ɛy |
T16101 |
33828-33834 |
NN |
denotes |
globin |
T16102 |
33835-33845 |
NN |
denotes |
initiation |
T16103 |
33846-33851 |
NN |
denotes |
codon |
T16104 |
33852-33853 |
-LRB- |
denotes |
( |
T16105 |
33853-33856 |
NN |
denotes |
ATG |
T16106 |
33856-33857 |
-RRB- |
denotes |
) |
T16107 |
33858-33861 |
VB |
denotes |
was |
T16108 |
33862-33866 |
VB |
denotes |
used |
T16109 |
33866-33867 |
-COMMA- |
denotes |
, |
T16110 |
33868-33875 |
IN |
denotes |
because |
T16111 |
33876-33878 |
PRP |
denotes |
it |
T16112 |
33879-33882 |
VB |
denotes |
has |
T16113 |
33883-33887 |
VB |
denotes |
been |
T16114 |
33888-33893 |
VB |
denotes |
shown |
T16115 |
33894-33898 |
IN |
denotes |
that |
T16116 |
33899-33902 |
DT |
denotes |
all |
T16117 |
33903-33912 |
NN |
denotes |
sequences |
T16118 |
33913-33921 |
VB |
denotes |
required |
T16119 |
33922-33925 |
IN |
denotes |
for |
T16120 |
33926-33927 |
NN |
denotes |
ɛ |
T16121 |
33928-33932 |
NN |
denotes |
gene |
T16122 |
33933-33942 |
NN |
denotes |
silencing |
T16123 |
33943-33946 |
VB |
denotes |
are |
T16124 |
33947-33954 |
JJ |
denotes |
located |
T16125 |
33955-33961 |
IN |
denotes |
within |
T16126 |
33962-33963 |
DT |
denotes |
a |
T16127 |
33964-33970 |
JJ |
denotes |
3.7-kb |
T16128 |
33971-33976 |
NN |
denotes |
EcoRI |
T16129 |
33977-33985 |
NN |
denotes |
fragment |
T16130 |
33986-33996 |
VB |
denotes |
containing |
T16131 |
33997-34002 |
IN |
denotes |
about |
T16132 |
34003-34004 |
CD |
denotes |
2 |
T16133 |
34005-34007 |
NN |
denotes |
kb |
T16134 |
34008-34010 |
IN |
denotes |
of |
T16135 |
34011-34019 |
NN |
denotes |
sequence |
T16136 |
34020-34028 |
RB |
denotes |
upstream |
T16137 |
34029-34031 |
IN |
denotes |
of |
T16138 |
34032-34035 |
DT |
denotes |
the |
T16139 |
34036-34037 |
NN |
denotes |
ɛ |
T16140 |
34038-34044 |
NN |
denotes |
globin |
T16141 |
34045-34049 |
NN |
denotes |
gene |
T16142 |
34050-34053 |
NN |
denotes |
cap |
T16143 |
34054-34058 |
NN |
denotes |
site |
T16144 |
34059-34060 |
-LRB- |
denotes |
[ |
T16145 |
34060-34062 |
CD |
denotes |
50 |
T16146 |
34062-34063 |
-RRB- |
denotes |
] |
T16147 |
34065-34075 |
NN |
denotes |
Nucleotide |
T16148 |
34076-34085 |
NN |
denotes |
numbering |
T16149 |
34086-34088 |
VB |
denotes |
is |
T16150 |
34089-34097 |
JJ |
denotes |
relative |
T16151 |
34098-34100 |
TO |
denotes |
to |
T16152 |
34101-34104 |
DT |
denotes |
the |
T16153 |
34105-34118 |
NN |
denotes |
transcription |
T16154 |
34119-34124 |
NN |
denotes |
start |
T16155 |
34125-34129 |
NN |
denotes |
site |
T16156 |
34131-34134 |
DT |
denotes |
The |
T16157 |
34135-34150 |
JJ |
denotes |
transcriptional |
T16158 |
34151-34156 |
NN |
denotes |
start |
T16159 |
34157-34161 |
NN |
denotes |
site |
T16160 |
34162-34164 |
VB |
denotes |
is |
T16161 |
34165-34170 |
VB |
denotes |
based |
T16162 |
34171-34173 |
IN |
denotes |
on |
T16163 |
34174-34177 |
DT |
denotes |
the |
T16164 |
34178-34185 |
JJ |
denotes |
longest |
T16165 |
34186-34190 |
NN |
denotes |
cDNA |
T16166 |
34191-34193 |
IN |
denotes |
in |
T16167 |
34194-34197 |
DT |
denotes |
the |
T16168 |
34198-34204 |
NNP |
denotes |
Fantom |
T16169 |
34205-34206 |
-LRB- |
denotes |
( |
T16170 |
34206-34216 |
JJ |
denotes |
Functional |
T16171 |
34217-34227 |
NN |
denotes |
Annotation |
T16172 |
34228-34230 |
IN |
denotes |
of |
T16173 |
34231-34236 |
NN |
denotes |
Mouse |
T16174 |
34236-34237 |
-RRB- |
denotes |
) |
T16175 |
34238-34246 |
NN |
denotes |
database |
T16176 |
34248-34251 |
DT |
denotes |
The |
T16177 |
34252-34255 |
NN |
denotes |
PCR |
T16178 |
34256-34263 |
NN |
denotes |
primers |
T16179 |
34264-34273 |
VB |
denotes |
contained |
T16180 |
34274-34278 |
NN |
denotes |
XhoI |
T16181 |
34279-34282 |
CC |
denotes |
and |
T16182 |
34283-34290 |
NN |
denotes |
HindIII |
T16183 |
34291-34296 |
NN |
denotes |
sites |
T16184 |
34297-34301 |
WDT |
denotes |
that |
T16185 |
34302-34306 |
VB |
denotes |
were |
T16186 |
34307-34311 |
VB |
denotes |
used |
T16187 |
34312-34314 |
TO |
denotes |
to |
T16188 |
34315-34320 |
VB |
denotes |
clone |
T16189 |
34321-34324 |
DT |
denotes |
the |
T16190 |
34325-34327 |
JJ |
denotes |
ɛy |
T16191 |
34328-34336 |
NN |
denotes |
promoter |
T16192 |
34337-34345 |
NN |
denotes |
fragment |
T16193 |
34346-34354 |
RB |
denotes |
upstream |
T16194 |
34355-34357 |
IN |
denotes |
of |
T16195 |
34358-34361 |
DT |
denotes |
the |
T16196 |
34362-34369 |
NN |
denotes |
firefly |
T16197 |
34370-34380 |
NN |
denotes |
luciferase |
T16198 |
34381-34385 |
NN |
denotes |
gene |
T16199 |
34386-34388 |
IN |
denotes |
in |
T16200 |
34389-34393 |
NN |
denotes |
pGL3 |
T16201 |
34394-34399 |
JJ |
denotes |
Basic |
T16202 |
34400-34401 |
-LRB- |
denotes |
( |
T16203 |
34401-34408 |
NNP |
denotes |
Promega |
T16204 |
34408-34409 |
-COMMA- |
denotes |
, |
T16205 |
34410-34417 |
NNP |
denotes |
Madison |
T16206 |
34417-34418 |
-COMMA- |
denotes |
, |
T16207 |
34419-34428 |
NNP |
denotes |
Wisconsin |
T16208 |
34428-34429 |
-COMMA- |
denotes |
, |
T16209 |
34430-34436 |
NNP |
denotes |
United |
T16210 |
34437-34443 |
NNP |
denotes |
States |
T16211 |
34443-34444 |
-RRB- |
denotes |
) |
T16212 |
34446-34447 |
DT |
denotes |
A |
T16213 |
34448-34454 |
JJ |
denotes |
2.5-kb |
T16214 |
34455-34464 |
NN |
denotes |
SstI/XhoI |
T16215 |
34465-34473 |
NN |
denotes |
fragment |
T16216 |
34474-34476 |
IN |
denotes |
of |
T16217 |
34477-34482 |
NN |
denotes |
μLCRβ |
T16218 |
34483-34486 |
CD |
denotes |
9.3 |
T16219 |
34487-34488 |
-LRB- |
denotes |
( |
T16220 |
34488-34493 |
NN |
denotes |
micro |
T16221 |
34494-34497 |
NN |
denotes |
LCR |
T16222 |
34497-34498 |
-COLON- |
denotes |
; |
T16223 |
34499-34500 |
-LRB- |
denotes |
[ |
T16224 |
34500-34502 |
CD |
denotes |
31 |
T16225 |
34502-34503 |
-RRB- |
denotes |
] |
T16226 |
34503-34504 |
-RRB- |
denotes |
) |
T16227 |
34505-34508 |
VB |
denotes |
was |
T16228 |
34509-34513 |
RB |
denotes |
then |
T16229 |
34514-34522 |
VB |
denotes |
inserted |
T16230 |
34523-34531 |
RB |
denotes |
upstream |
T16231 |
34532-34534 |
IN |
denotes |
of |
T16232 |
34535-34538 |
DT |
denotes |
the |
T16233 |
34539-34541 |
JJ |
denotes |
ɛy |
T16234 |
34542-34550 |
NN |
denotes |
promoter |
T16235 |
34551-34553 |
IN |
denotes |
in |
T16236 |
34554-34557 |
DT |
denotes |
the |
T16237 |
34558-34563 |
JJ |
denotes |
above |
T16238 |
34564-34568 |
NN |
denotes |
pGL3 |
T16239 |
34569-34574 |
JJ |
denotes |
Basic |
T16240 |
34575-34582 |
NN |
denotes |
plasmid |
T16241 |
34582-34583 |
-COMMA- |
denotes |
, |
T16242 |
34584-34593 |
VB |
denotes |
resulting |
T16243 |
34594-34596 |
IN |
denotes |
in |
T16244 |
34597-34598 |
DT |
denotes |
a |
T16245 |
34599-34607 |
NN |
denotes |
reporter |
T16246 |
34608-34617 |
NN |
denotes |
construct |
T16247 |
34618-34620 |
IN |
denotes |
in |
T16248 |
34621-34626 |
WDT |
denotes |
which |
T16249 |
34627-34637 |
NN |
denotes |
luciferase |
T16250 |
34638-34648 |
NN |
denotes |
expression |
T16251 |
34649-34651 |
VB |
denotes |
is |
T16252 |
34652-34658 |
VB |
denotes |
driven |
T16253 |
34659-34661 |
IN |
denotes |
by |
T16254 |
34662-34665 |
DT |
denotes |
the |
T16255 |
34666-34668 |
JJ |
denotes |
ɛy |
T16256 |
34669-34677 |
NN |
denotes |
promoter |
T16257 |
34679-34680 |
DT |
denotes |
A |
T16258 |
34681-34687 |
NN |
denotes |
series |
T16259 |
34688-34690 |
IN |
denotes |
of |
T16260 |
34691-34699 |
NN |
denotes |
deletion |
T16261 |
34700-34710 |
NN |
denotes |
constructs |
T16262 |
34711-34713 |
IN |
denotes |
of |
T16263 |
34714-34717 |
DT |
denotes |
the |
T16264 |
34718-34720 |
JJ |
denotes |
ɛy |
T16265 |
34721-34729 |
NN |
denotes |
promoter |
T16266 |
34730-34734 |
VB |
denotes |
were |
T16267 |
34735-34744 |
VB |
denotes |
generated |
T16268 |
34745-34754 |
RB |
denotes |
similarly |
T16269 |
34756-34763 |
JJ |
denotes |
Forward |
T16270 |
34764-34771 |
NN |
denotes |
primers |
T16271 |
34772-34776 |
IN |
denotes |
with |
T16272 |
34777-34779 |
DT |
denotes |
an |
T16273 |
34780-34784 |
NN |
denotes |
XhoI |
T16274 |
34785-34789 |
NN |
denotes |
site |
T16275 |
34790-34797 |
VB |
denotes |
include |
T16276 |
34797-34798 |
-COLON- |
denotes |
: |
T16277 |
34799-34806 |
NN |
denotes |
MHB1457 |
T16278 |
34806-34807 |
-COMMA- |
denotes |
, |
T16279 |
34808-34838 |
NN |
denotes |
5′CCGCTCGAGTGCTAGGCAAACACTCA3′ |
T16280 |
34839-34840 |
-LRB- |
denotes |
( |
T16281 |
34840-34845 |
CD |
denotes |
−2077 |
T16282 |
34846-34848 |
TO |
denotes |
to |
T16283 |
34849-34854 |
CD |
denotes |
−2052 |
T16284 |
34854-34855 |
-RRB- |
denotes |
) |
T16285 |
34855-34856 |
-COLON- |
denotes |
; |
T16286 |
34857-34864 |
NN |
denotes |
MHB1503 |
T16287 |
34864-34865 |
-COMMA- |
denotes |
, |
T16288 |
34866-34900 |
NN |
denotes |
5′CCGCTCGAGTCTCTACACTGTCACTCCCTG3′ |
T16289 |
34901-34902 |
-LRB- |
denotes |
( |
T16290 |
34902-34906 |
CD |
denotes |
−634 |
T16291 |
34907-34909 |
TO |
denotes |
to |
T16292 |
34910-34914 |
CD |
denotes |
−605 |
T16293 |
34914-34915 |
-RRB- |
denotes |
) |
T16294 |
34915-34916 |
-COLON- |
denotes |
; |
T16295 |
34917-34924 |
NN |
denotes |
MHB1505 |
T16296 |
34924-34925 |
-COMMA- |
denotes |
, |
T16297 |
34926-34958 |
NN |
denotes |
5′CCGCTCGAGGGAGCCAAAAAAAGAATGC3′ |
T16298 |
34959-34960 |
-LRB- |
denotes |
( |
T16299 |
34960-34964 |
CD |
denotes |
−197 |
T16300 |
34965-34967 |
TO |
denotes |
to |
T16301 |
34968-34972 |
CD |
denotes |
−169 |
T16302 |
34972-34973 |
-RRB- |
denotes |
) |
T16303 |
34973-34974 |
-COLON- |
denotes |
; |
T16304 |
34975-34982 |
NN |
denotes |
MHB1506 |
T16305 |
34982-34983 |
-COMMA- |
denotes |
, |
T16306 |
34984-35016 |
NN |
denotes |
5′CCGCTCGAGCTGACCAATGGCTTCAAAG3′ |
T16307 |
35017-35018 |
-LRB- |
denotes |
( |
T16308 |
35018-35021 |
CD |
denotes |
−85 |
T16309 |
35022-35024 |
TO |
denotes |
to |
T16310 |
35025-35028 |
CD |
denotes |
−58 |
T16311 |
35028-35029 |
-RRB- |
denotes |
) |
T16312 |
35029-35030 |
-COLON- |
denotes |
; |
T16313 |
35031-35038 |
NN |
denotes |
MHB1532 |
T16314 |
35038-35039 |
-COMMA- |
denotes |
, |
T16315 |
35040-35074 |
NN |
denotes |
5′CCGCTCGAGAATGCAGAACAAAGGGTCAGA3′ |
T16316 |
35075-35076 |
-LRB- |
denotes |
( |
T16317 |
35076-35079 |
CD |
denotes |
−63 |
T16318 |
35080-35082 |
TO |
denotes |
to |
T16319 |
35083-35086 |
CD |
denotes |
−34 |
T16320 |
35086-35087 |
-RRB- |
denotes |
) |
T16321 |
35087-35088 |
-COLON- |
denotes |
; |
T16322 |
35089-35092 |
CC |
denotes |
and |
T16323 |
35093-35100 |
NN |
denotes |
MHB1507 |
T16324 |
35100-35101 |
-COMMA- |
denotes |
, |
T16325 |
35102-35133 |
NN |
denotes |
5′CCGCTCGAGGTCTGCGAAGAATAAAAGGC |
T16326 |
35134-35136 |
NN |
denotes |
3′ |
T16327 |
35137-35138 |
-LRB- |
denotes |
( |
T16328 |
35138-35141 |
CD |
denotes |
−37 |
T16329 |
35142-35144 |
TO |
denotes |
to |
T16330 |
35145-35147 |
CD |
denotes |
−9 |
T16331 |
35147-35148 |
-RRB- |
denotes |
) |
T16332 |
35150-35153 |
DT |
denotes |
All |
T16333 |
35154-35161 |
JJ |
denotes |
forward |
T16334 |
35162-35169 |
NN |
denotes |
primers |
T16335 |
35170-35174 |
VB |
denotes |
were |
T16336 |
35175-35179 |
VB |
denotes |
used |
T16337 |
35180-35182 |
IN |
denotes |
in |
T16338 |
35183-35194 |
NN |
denotes |
combination |
T16339 |
35195-35199 |
IN |
denotes |
with |
T16340 |
35200-35203 |
DT |
denotes |
the |
T16341 |
35204-35211 |
JJ |
denotes |
reverse |
T16342 |
35212-35218 |
NN |
denotes |
primer |
T16343 |
35219-35226 |
NN |
denotes |
HindIII |
T16344 |
35227-35231 |
NN |
denotes |
site |
T16345 |
35231-35232 |
-COLON- |
denotes |
: |
T16346 |
35233-35240 |
NN |
denotes |
MHB1477 |
T16347 |
35240-35241 |
-COMMA- |
denotes |
, |
T16348 |
35242-35271 |
NN |
denotes |
5′CGGAAGCTTGGGAGGTTGCTGGTGA3′ |
T16349 |
35272-35273 |
-LRB- |
denotes |
( |
T16350 |
35273-35276 |
CD |
denotes |
+45 |
T16351 |
35277-35279 |
TO |
denotes |
to |
T16352 |
35280-35283 |
CD |
denotes |
+20 |
T16353 |
35283-35284 |
-RRB- |
denotes |
) |
T16354 |
35286-35299 |
NN |
denotes |
Sox6-pcDNA3.1 |
T16355 |
35300-35301 |
-LRB- |
denotes |
[ |
T16356 |
35301-35303 |
CD |
denotes |
15 |
T16357 |
35303-35304 |
-RRB- |
denotes |
] |
T16358 |
35305-35308 |
VB |
denotes |
was |
T16359 |
35309-35313 |
VB |
denotes |
used |
T16360 |
35314-35316 |
TO |
denotes |
to |
T16361 |
35317-35328 |
VB |
denotes |
overexpress |
T16362 |
35329-35333 |
NN |
denotes |
Sox6 |
T16363 |
35335-35336 |
DT |
denotes |
A |
T16364 |
35337-35346 |
VB |
denotes |
truncated |
T16365 |
35347-35354 |
NN |
denotes |
version |
T16366 |
35355-35357 |
IN |
denotes |
of |
T16367 |
35358-35361 |
DT |
denotes |
the |
T16368 |
35362-35366 |
NN |
denotes |
Sox6 |
T16369 |
35367-35381 |
NN |
denotes |
overexpression |
T16370 |
35382-35391 |
NN |
denotes |
construct |
T16371 |
35392-35393 |
-LRB- |
denotes |
( |
T16372 |
35393-35411 |
NN |
denotes |
Sox6-ΔHMG-pcDNA3.1 |
T16373 |
35411-35412 |
-RRB- |
denotes |
) |
T16374 |
35413-35417 |
WDT |
denotes |
that |
T16375 |
35418-35423 |
VB |
denotes |
lacks |
T16376 |
35424-35427 |
DT |
denotes |
the |
T16377 |
35428-35431 |
NN |
denotes |
HMG |
T16378 |
35432-35438 |
NN |
denotes |
domain |
T16379 |
35439-35442 |
VB |
denotes |
was |
T16380 |
35443-35452 |
VB |
denotes |
generated |
T16381 |
35452-35453 |
-COMMA- |
denotes |
, |
T16382 |
35454-35456 |
IN |
denotes |
as |
T16383 |
35457-35466 |
VB |
denotes |
described |
T16384 |
35467-35469 |
IN |
denotes |
by |
T16385 |
35470-35476 |
NN |
denotes |
others |
T16386 |
35477-35478 |
-LRB- |
denotes |
[ |
T16387 |
35478-35480 |
CD |
denotes |
32 |
T16388 |
35480-35481 |
-RRB- |
denotes |
] |
T16389 |
35483-35494 |
NN |
denotes |
Mutagenesis |
T16390 |
35495-35497 |
IN |
denotes |
of |
T16391 |
35498-35506 |
NN |
denotes |
Sox/Sox6 |
T16392 |
35507-35516 |
NN |
denotes |
consensus |
T16393 |
35517-35524 |
NN |
denotes |
binding |
T16394 |
35525-35530 |
NN |
denotes |
sites |
T16395 |
35531-35533 |
IN |
denotes |
of |
T16396 |
35534-35537 |
DT |
denotes |
the |
T16397 |
35538-35540 |
JJ |
denotes |
ɛy |
T16398 |
35541-35549 |
NN |
denotes |
promoter |
T16399 |
35550-35554 |
VB |
denotes |
were |
T16400 |
35555-35559 |
VB |
denotes |
done |
T16401 |
35560-35562 |
IN |
denotes |
by |
T16402 |
35563-35566 |
NN |
denotes |
PCR |
T16403 |
35568-35575 |
JJ |
denotes |
Forward |
T16404 |
35576-35583 |
NN |
denotes |
primers |
T16405 |
35584-35588 |
VB |
denotes |
used |
T16406 |
35589-35591 |
TO |
denotes |
to |
T16407 |
35592-35600 |
VB |
denotes |
generate |
T16408 |
35601-35606 |
DT |
denotes |
these |
T16409 |
35607-35618 |
VB |
denotes |
mutagenized |
T16410 |
35619-35621 |
NN |
denotes |
ɛy |
T16411 |
35622-35630 |
NN |
denotes |
promoter |
T16412 |
35631-35639 |
NN |
denotes |
reporter |
T16413 |
35640-35650 |
NN |
denotes |
constructs |
T16414 |
35651-35658 |
VB |
denotes |
include |
T16415 |
35658-35659 |
-COLON- |
denotes |
: |
T16416 |
35660-35667 |
NN |
denotes |
MHB1661 |
T16417 |
35667-35668 |
-COMMA- |
denotes |
, |
T16418 |
35669-35718 |
NN |
denotes |
5′CCGCTCGAGAATGCAGTGCCAAGGGTCAGAACATTGTCTGCGAAG3′ |
T16419 |
35719-35720 |
-LRB- |
denotes |
( |
T16420 |
35720-35723 |
CD |
denotes |
−63 |
T16421 |
35724-35726 |
TO |
denotes |
to |
T16422 |
35727-35730 |
CD |
denotes |
−19 |
T16423 |
35730-35731 |
-RRB- |
denotes |
) |
T16424 |
35731-35732 |
-COLON- |
denotes |
; |
T16425 |
35733-35740 |
NN |
denotes |
MHB1662 |
T16426 |
35740-35741 |
-COMMA- |
denotes |
, |
T16427 |
35742-35793 |
NN |
denotes |
5′CCGCTCGAGAATGCAGAACAAAGGGTCAGATGAGTGTCTGCGAAGAA3′ |
T16428 |
35794-35795 |
-LRB- |
denotes |
( |
T16429 |
35795-35798 |
CD |
denotes |
−63 |
T16430 |
35799-35801 |
TO |
denotes |
to |
T16431 |
35802-35805 |
CD |
denotes |
−16 |
T16432 |
35805-35806 |
-RRB- |
denotes |
) |
T16433 |
35806-35807 |
-COLON- |
denotes |
; |
T16434 |
35808-35811 |
CC |
denotes |
and |
T16435 |
35812-35819 |
NN |
denotes |
MHB1663 |
T16436 |
35819-35820 |
-COMMA- |
denotes |
, |
T16437 |
35821-35869 |
NN |
denotes |
5′CCGCTCGAGAATGCATGCCAAGGGTCAGATGAGTGTCTGCGAAGAA |
T16438 |
35870-35872 |
NN |
denotes |
3′ |
T16439 |
35873-35874 |
-LRB- |
denotes |
( |
T16440 |
35874-35877 |
CD |
denotes |
−63 |
T16441 |
35878-35880 |
TO |
denotes |
to |
T16442 |
35881-35884 |
CD |
denotes |
−18 |
T16443 |
35884-35885 |
-RRB- |
denotes |
) |
T17191 |
35888-35900 |
NN |
denotes |
Quantitation |
T17192 |
35901-35903 |
IN |
denotes |
of |
T17193 |
35904-35910 |
NN |
denotes |
globin |
T17194 |
35911-35915 |
NN |
denotes |
mRNA |
T17195 |
35917-35920 |
NN |
denotes |
RNA |
T17196 |
35921-35924 |
VB |
denotes |
was |
T17197 |
35925-35930 |
RB |
denotes |
first |
T17198 |
35931-35938 |
JJ |
denotes |
reverse |
T17199 |
35939-35950 |
VB |
denotes |
transcribed |
T17200 |
35951-35953 |
TO |
denotes |
to |
T17201 |
35954-35958 |
NN |
denotes |
cDNA |
T17202 |
35960-35967 |
NN |
denotes |
Primers |
T17203 |
35968-35971 |
IN |
denotes |
for |
T17204 |
35972-35976 |
NN |
denotes |
cDNA |
T17205 |
35977-35980 |
NN |
denotes |
PCR |
T17206 |
35981-35994 |
NN |
denotes |
amplification |
T17207 |
35995-35997 |
IN |
denotes |
of |
T17208 |
35998-36004 |
NN |
denotes |
globin |
T17209 |
36005-36010 |
NN |
denotes |
genes |
T17210 |
36011-36015 |
VB |
denotes |
were |
T17211 |
36016-36024 |
VB |
denotes |
obtained |
T17212 |
36025-36029 |
IN |
denotes |
from |
T17213 |
36030-36040 |
NNP |
denotes |
Primerbank |
T17214 |
36041-36042 |
-LRB- |
denotes |
[ |
T17215 |
36042-36044 |
CD |
denotes |
51 |
T17216 |
36044-36045 |
-RRB- |
denotes |
] |
T17217 |
36047-36050 |
DT |
denotes |
All |
T17218 |
36051-36058 |
NN |
denotes |
primers |
T17219 |
36059-36063 |
VB |
denotes |
were |
T17220 |
36064-36072 |
VB |
denotes |
searched |
T17221 |
36073-36080 |
IN |
denotes |
against |
T17222 |
36081-36084 |
DT |
denotes |
the |
T17223 |
36085-36089 |
NN |
denotes |
NCBI |
T17224 |
36090-36098 |
NN |
denotes |
database |
T17225 |
36099-36101 |
TO |
denotes |
to |
T17226 |
36102-36109 |
VB |
denotes |
confirm |
T17227 |
36110-36121 |
NN |
denotes |
specificity |
T17228 |
36123-36126 |
IN |
denotes |
For |
T17229 |
36127-36129 |
JJ |
denotes |
ɛy |
T17230 |
36130-36136 |
NN |
denotes |
globin |
T17231 |
36136-36137 |
-COLON- |
denotes |
: |
T17232 |
36138-36145 |
NN |
denotes |
MHB1666 |
T17233 |
36145-36146 |
-COMMA- |
denotes |
, |
T17234 |
36147-36172 |
NN |
denotes |
5′TGGCCTGTGGAGTAAGGTCAA3′ |
T17235 |
36172-36173 |
-COLON- |
denotes |
; |
T17236 |
36174-36177 |
CC |
denotes |
and |
T17237 |
36178-36185 |
NN |
denotes |
MHB1667 |
T17238 |
36185-36186 |
-COMMA- |
denotes |
, |
T17239 |
36187-36212 |
NN |
denotes |
5′GAAGCAGAGGACAAGTTCCCA3′ |
T17240 |
36214-36217 |
IN |
denotes |
For |
T17241 |
36218-36219 |
NN |
denotes |
ζ |
T17242 |
36220-36226 |
NN |
denotes |
globin |
T17243 |
36226-36227 |
-COLON- |
denotes |
: |
T17244 |
36228-36235 |
NN |
denotes |
MHB1668 |
T17245 |
36235-36236 |
-COMMA- |
denotes |
, |
T17246 |
36237-36262 |
NN |
denotes |
5′CTACCCCCAGACGAAGACCTA3′ |
T17247 |
36262-36263 |
-COLON- |
denotes |
; |
T17248 |
36264-36267 |
CC |
denotes |
and |
T17249 |
36268-36275 |
NN |
denotes |
MHB1669 |
T17250 |
36275-36276 |
-COMMA- |
denotes |
, |
T17251 |
36277-36301 |
NN |
denotes |
5′CTTAACCGCATCCCCTACGG3′ |
T17252 |
36303-36306 |
IN |
denotes |
For |
T17253 |
36307-36310 |
NN |
denotes |
βH1 |
T17254 |
36311-36317 |
NN |
denotes |
globin |
T17255 |
36317-36318 |
-COLON- |
denotes |
: |
T17256 |
36319-36326 |
NN |
denotes |
MHB1672 |
T17257 |
36326-36327 |
-COMMA- |
denotes |
, |
T17258 |
36328-36352 |
NN |
denotes |
5′TGGACAACCTCAAGGAGACC3′ |
T17259 |
36352-36353 |
-COLON- |
denotes |
; |
T17260 |
36354-36357 |
CC |
denotes |
and |
T17261 |
36358-36365 |
NN |
denotes |
MHB1673 |
T17262 |
36365-36366 |
-COMMA- |
denotes |
, |
T17263 |
36367-36391 |
NN |
denotes |
5′ACCTCTGGGGTGAATTCCTT3′ |
T17264 |
36393-36396 |
IN |
denotes |
For |
T17265 |
36397-36405 |
NN |
denotes |
βmaj/min |
T17266 |
36406-36412 |
NN |
denotes |
globin |
T17267 |
36412-36413 |
-COLON- |
denotes |
: |
T17268 |
36414-36421 |
NN |
denotes |
MHB1674 |
T17269 |
36421-36422 |
-COLON- |
denotes |
: |
T17270 |
36423-36447 |
NN |
denotes |
5′ATGGCCTGAATCACTTGGAC3′ |
T17271 |
36447-36448 |
-COLON- |
denotes |
; |
T17272 |
36449-36452 |
CC |
denotes |
and |
T17273 |
36453-36460 |
NN |
denotes |
MHB1675 |
T17274 |
36460-36461 |
-COMMA- |
denotes |
, |
T17275 |
36462-36486 |
NN |
denotes |
5′ACGATCATATTGCCCAGGAG3′ |
T17276 |
36488-36493 |
VB |
denotes |
Using |
T17277 |
36494-36497 |
DT |
denotes |
the |
T17278 |
36498-36502 |
NN |
denotes |
SYBR |
T17279 |
36503-36508 |
JJ |
denotes |
green |
T17280 |
36509-36517 |
NN |
denotes |
supermix |
T17281 |
36518-36521 |
NN |
denotes |
kit |
T17282 |
36522-36526 |
IN |
denotes |
with |
T17283 |
36527-36530 |
NN |
denotes |
ROX |
T17284 |
36531-36532 |
-LRB- |
denotes |
( |
T17285 |
36532-36539 |
NNP |
denotes |
Bio-Rad |
T17286 |
36539-36540 |
-COMMA- |
denotes |
, |
T17287 |
36541-36549 |
NNP |
denotes |
Hercules |
T17288 |
36549-36550 |
-COMMA- |
denotes |
, |
T17289 |
36551-36561 |
NNP |
denotes |
California |
T17290 |
36561-36562 |
-COMMA- |
denotes |
, |
T17291 |
36563-36569 |
NNP |
denotes |
United |
T17292 |
36570-36576 |
NNP |
denotes |
States |
T17293 |
36576-36577 |
-RRB- |
denotes |
) |
T17294 |
36577-36578 |
-COMMA- |
denotes |
, |
T17295 |
36579-36582 |
NN |
denotes |
PCR |
T17296 |
36583-36596 |
NN |
denotes |
amplification |
T17297 |
36597-36600 |
VB |
denotes |
was |
T17298 |
36601-36604 |
VB |
denotes |
run |
T17299 |
36605-36607 |
IN |
denotes |
on |
T17300 |
36608-36610 |
DT |
denotes |
an |
T17301 |
36611-36618 |
NN |
denotes |
ABI7000 |
T17302 |
36619-36620 |
-LRB- |
denotes |
( |
T17303 |
36620-36627 |
NNP |
denotes |
Applied |
T17304 |
36628-36638 |
NNP |
denotes |
Biosystems |
T17305 |
36638-36639 |
-COMMA- |
denotes |
, |
T17306 |
36640-36646 |
NNP |
denotes |
Foster |
T17307 |
36647-36651 |
NNP |
denotes |
City |
T17308 |
36651-36652 |
-COMMA- |
denotes |
, |
T17309 |
36653-36663 |
NNP |
denotes |
California |
T17310 |
36663-36664 |
-COMMA- |
denotes |
, |
T17311 |
36665-36671 |
NNP |
denotes |
United |
T17312 |
36672-36678 |
NNP |
denotes |
States |
T17313 |
36678-36679 |
-RRB- |
denotes |
) |
T17314 |
36680-36682 |
IN |
denotes |
at |
T17315 |
36683-36686 |
DT |
denotes |
the |
T17316 |
36687-36697 |
NNP |
denotes |
University |
T17317 |
36698-36700 |
IN |
denotes |
of |
T17318 |
36701-36708 |
NNP |
denotes |
Arizona |
T17319 |
36709-36713 |
NN |
denotes |
core |
T17320 |
36714-36722 |
NN |
denotes |
facility |
T17321 |
36724-36727 |
DT |
denotes |
All |
T17322 |
36728-36731 |
NN |
denotes |
PCR |
T17323 |
36732-36735 |
VB |
denotes |
was |
T17324 |
36736-36745 |
VB |
denotes |
performed |
T17325 |
36746-36748 |
IN |
denotes |
in |
T17326 |
36749-36750 |
DT |
denotes |
a |
T17327 |
36751-36756 |
JJ |
denotes |
25-μl |
T17328 |
36757-36765 |
NN |
denotes |
reaction |
T17329 |
36766-36770 |
IN |
denotes |
with |
T17330 |
36771-36775 |
CD |
denotes |
12.5 |
T17331 |
36776-36778 |
NN |
denotes |
μl |
T17332 |
36779-36783 |
NN |
denotes |
SYBR |
T17333 |
36784-36789 |
JJ |
denotes |
green |
T17334 |
36790-36798 |
NN |
denotes |
supermix |
T17335 |
36800-36805 |
NN |
denotes |
GAPDH |
T17336 |
36806-36810 |
NN |
denotes |
mRNA |
T17337 |
36811-36817 |
NN |
denotes |
levels |
T17338 |
36818-36822 |
VB |
denotes |
were |
T17339 |
36823-36827 |
VB |
denotes |
used |
T17340 |
36828-36830 |
IN |
denotes |
as |
T17341 |
36831-36838 |
NN |
denotes |
control |
T17342 |
36839-36842 |
IN |
denotes |
for |
T17343 |
36843-36848 |
NN |
denotes |
input |
T17344 |
36849-36852 |
NN |
denotes |
RNA |
T17345 |
36854-36862 |
JJ |
denotes |
Standard |
T17346 |
36863-36868 |
NN |
denotes |
curve |
T17347 |
36869-36877 |
NN |
denotes |
analyses |
T17348 |
36878-36882 |
VB |
denotes |
were |
T17349 |
36883-36892 |
VB |
denotes |
performed |
T17350 |
36893-36895 |
TO |
denotes |
to |
T17351 |
36896-36900 |
VB |
denotes |
test |
T17352 |
36901-36904 |
DT |
denotes |
the |
T17353 |
36905-36915 |
NN |
denotes |
efficiency |
T17354 |
36916-36918 |
IN |
denotes |
of |
T17355 |
36919-36922 |
DT |
denotes |
the |
T17356 |
36923-36937 |
NN |
denotes |
amplifications |
T17357 |
36939-36950 |
NN |
denotes |
Triplicates |
T17358 |
36951-36955 |
VB |
denotes |
were |
T17359 |
36956-36960 |
VB |
denotes |
done |
T17360 |
36961-36964 |
IN |
denotes |
for |
T17361 |
36965-36969 |
DT |
denotes |
each |
T17362 |
36970-36973 |
NN |
denotes |
PCR |
T17363 |
36974-36982 |
NN |
denotes |
reaction |
T17364 |
36984-36992 |
JJ |
denotes |
Relative |
T17365 |
36993-37005 |
JJ |
denotes |
quantitative |
T17366 |
37006-37012 |
NN |
denotes |
values |
T17367 |
37013-37017 |
VB |
denotes |
were |
T17368 |
37018-37028 |
VB |
denotes |
calculated |
T17369 |
37029-37031 |
IN |
denotes |
in |
T17370 |
37032-37035 |
DT |
denotes |
the |
T17371 |
37036-37039 |
NNP |
denotes |
ABI |
T17372 |
37040-37045 |
NNP |
denotes |
Prism |
T17373 |
37046-37050 |
CD |
denotes |
7000 |
T17374 |
37051-37054 |
NNP |
denotes |
SDS |
T17375 |
37055-37063 |
NNP |
denotes |
Software |
T17376 |
37064-37065 |
-LRB- |
denotes |
( |
T17377 |
37065-37072 |
NNP |
denotes |
Applied |
T17378 |
37073-37083 |
NNP |
denotes |
Biosystems |
T17379 |
37083-37084 |
-RRB- |
denotes |
) |
T17380 |
37085-37088 |
CC |
denotes |
and |
T17381 |
37089-37099 |
VB |
denotes |
normalized |
T17382 |
37100-37102 |
TO |
denotes |
to |
T17383 |
37103-37108 |
NN |
denotes |
GAPDH |
T17384 |
37109-37111 |
IN |
denotes |
in |
T17385 |
37112-37121 |
NNP |
denotes |
Microsoft |
T17386 |
37122-37127 |
NNP |
denotes |
Excel |
T17387 |
37128-37129 |
-LRB- |
denotes |
( |
T17388 |
37129-37136 |
NNP |
denotes |
Redmond |
T17389 |
37136-37137 |
-COMMA- |
denotes |
, |
T17390 |
37138-37148 |
NNP |
denotes |
Washington |
T17391 |
37148-37149 |
-COMMA- |
denotes |
, |
T17392 |
37150-37156 |
NNP |
denotes |
United |
T17393 |
37157-37163 |
NNP |
denotes |
States |
T17394 |
37163-37164 |
-RRB- |
denotes |
) |
T17766 |
37167-37169 |
FW |
denotes |
In |
T17767 |
37170-37174 |
FW |
denotes |
situ |
T17768 |
37175-37188 |
NN |
denotes |
hybridization |
T17769 |
37190-37199 |
JJ |
denotes |
Antisense |
T17770 |
37200-37206 |
NN |
denotes |
probes |
T17771 |
37207-37211 |
VB |
denotes |
were |
T17772 |
37212-37220 |
VB |
denotes |
designed |
T17773 |
37221-37223 |
TO |
denotes |
to |
T17774 |
37224-37230 |
JJ |
denotes |
murine |
T17775 |
37231-37233 |
JJ |
denotes |
ɛy |
T17776 |
37234-37240 |
NN |
denotes |
globin |
T17777 |
37241-37252 |
NN |
denotes |
nucleotides |
T17778 |
37253-37260 |
CD |
denotes |
509–584 |
T17779 |
37260-37261 |
-COLON- |
denotes |
; |
T17780 |
37262-37266 |
SYM |
denotes |
βmaj |
T17781 |
37267-37273 |
NN |
denotes |
globin |
T17782 |
37274-37285 |
NN |
denotes |
nucleotides |
T17783 |
37286-37293 |
CD |
denotes |
458–549 |
T17784 |
37293-37294 |
-COLON- |
denotes |
; |
T17785 |
37295-37298 |
CC |
denotes |
and |
T17786 |
37299-37304 |
NN |
denotes |
mouse |
T17787 |
37305-37309 |
NN |
denotes |
Sox6 |
T17788 |
37310-37321 |
NN |
denotes |
nucleotides |
T17789 |
37322-37331 |
CD |
denotes |
1353–1927 |
T17790 |
37333-37340 |
NN |
denotes |
Embryos |
T17791 |
37341-37345 |
VB |
denotes |
were |
T17792 |
37346-37351 |
VB |
denotes |
fixed |
T17793 |
37352-37361 |
RB |
denotes |
overnight |
T17794 |
37362-37364 |
IN |
denotes |
by |
T17795 |
37365-37374 |
NN |
denotes |
immersion |
T17796 |
37375-37377 |
IN |
denotes |
in |
T17797 |
37378-37379 |
CD |
denotes |
4 |
T17798 |
37379-37380 |
NN |
denotes |
% |
T17799 |
37381-37397 |
NN |
denotes |
paraformaldehyde |
T17800 |
37397-37398 |
-COMMA- |
denotes |
, |
T17801 |
37399-37407 |
VB |
denotes |
embedded |
T17802 |
37408-37410 |
IN |
denotes |
in |
T17803 |
37411-37419 |
NN |
denotes |
paraffin |
T17804 |
37419-37420 |
-COMMA- |
denotes |
, |
T17805 |
37421-37430 |
VB |
denotes |
sectioned |
T17806 |
37431-37433 |
IN |
denotes |
at |
T17807 |
37434-37435 |
CD |
denotes |
5 |
T17808 |
37436-37438 |
NN |
denotes |
μm |
T17809 |
37438-37439 |
-COMMA- |
denotes |
, |
T17810 |
37440-37443 |
CC |
denotes |
and |
T17811 |
37444-37451 |
VB |
denotes |
adhered |
T17812 |
37452-37454 |
TO |
denotes |
to |
T17813 |
37455-37461 |
VB |
denotes |
charge |
T17814 |
37462-37470 |
VB |
denotes |
modified |
T17815 |
37471-37477 |
NN |
denotes |
slides |
T17816 |
37478-37479 |
-LRB- |
denotes |
( |
T17817 |
37479-37482 |
NN |
denotes |
VWR |
T17818 |
37482-37483 |
-COMMA- |
denotes |
, |
T17819 |
37484-37488 |
NNP |
denotes |
West |
T17820 |
37489-37496 |
NNP |
denotes |
Chester |
T17821 |
37496-37497 |
-COMMA- |
denotes |
, |
T17822 |
37498-37510 |
NNP |
denotes |
Pennsylvania |
T17823 |
37510-37511 |
-COMMA- |
denotes |
, |
T17824 |
37512-37518 |
NNP |
denotes |
United |
T17825 |
37519-37525 |
NNP |
denotes |
States |
T17826 |
37525-37526 |
-RRB- |
denotes |
) |
T17827 |
37528-37534 |
NN |
denotes |
Slides |
T17828 |
37535-37539 |
VB |
denotes |
were |
T17829 |
37540-37549 |
VB |
denotes |
processed |
T17830 |
37550-37553 |
IN |
denotes |
for |
T17831 |
37554-37556 |
FW |
denotes |
in |
T17832 |
37557-37561 |
FW |
denotes |
situ |
T17833 |
37562-37575 |
NN |
denotes |
hybridization |
T17834 |
37576-37578 |
IN |
denotes |
as |
T17835 |
37579-37588 |
VB |
denotes |
described |
T17836 |
37589-37590 |
-LRB- |
denotes |
[ |
T17837 |
37590-37592 |
CD |
denotes |
52 |
T17838 |
37592-37593 |
-RRB- |
denotes |
] |
T17839 |
37594-37599 |
VB |
denotes |
using |
T17840 |
37600-37602 |
FW |
denotes |
in |
T17841 |
37603-37608 |
FW |
denotes |
vitro |
T17842 |
37609-37620 |
VB |
denotes |
transcribed |
T17843 |
37621-37624 |
NN |
denotes |
RNA |
T17844 |
37625-37631 |
NN |
denotes |
probes |
T17845 |
37632-37639 |
VB |
denotes |
labeled |
T17846 |
37640-37644 |
IN |
denotes |
with |
T17847 |
37645-37648 |
NN |
denotes |
33P |
T17848 |
37650-37659 |
NN |
denotes |
Darkfield |
T17849 |
37660-37663 |
CC |
denotes |
and |
T17850 |
37664-37675 |
NN |
denotes |
brightfield |
T17851 |
37676-37682 |
NN |
denotes |
images |
T17852 |
37683-37687 |
VB |
denotes |
were |
T17853 |
37688-37696 |
VB |
denotes |
obtained |
T17854 |
37697-37701 |
IN |
denotes |
with |
T17855 |
37702-37703 |
DT |
denotes |
a |
T17856 |
37704-37709 |
NNP |
denotes |
Nikon |
T17857 |
37710-37718 |
NNP |
denotes |
Optiphot |
T17858 |
37719-37729 |
NN |
denotes |
microscope |
T17859 |
37730-37731 |
-LRB- |
denotes |
( |
T17860 |
37731-37736 |
NNP |
denotes |
Nikon |
T17861 |
37736-37737 |
-COMMA- |
denotes |
, |
T17862 |
37738-37746 |
NNP |
denotes |
Melville |
T17863 |
37746-37747 |
-COMMA- |
denotes |
, |
T17864 |
37748-37751 |
NNP |
denotes |
New |
T17865 |
37752-37756 |
NNP |
denotes |
York |
T17866 |
37756-37757 |
-COMMA- |
denotes |
, |
T17867 |
37758-37764 |
NNP |
denotes |
United |
T17868 |
37765-37771 |
NNP |
denotes |
States |
T17869 |
37771-37772 |
-RRB- |
denotes |
) |
T17870 |
37773-37776 |
CC |
denotes |
and |
T17871 |
37777-37781 |
NN |
denotes |
SPOT |
T17872 |
37782-37791 |
NN |
denotes |
RT-Slider |
T17873 |
37792-37799 |
JJ |
denotes |
digital |
T17874 |
37800-37806 |
NN |
denotes |
camera |
T17875 |
37807-37808 |
-LRB- |
denotes |
( |
T17876 |
37808-37818 |
JJ |
denotes |
Diagnostic |
T17877 |
37819-37830 |
NNP |
denotes |
Instruments |
T17878 |
37830-37831 |
-COMMA- |
denotes |
, |
T17879 |
37832-37840 |
NNP |
denotes |
Sterling |
T17880 |
37841-37848 |
NNP |
denotes |
Heights |
T17881 |
37848-37849 |
-COMMA- |
denotes |
, |
T17882 |
37850-37858 |
NNP |
denotes |
Michigan |
T17883 |
37858-37859 |
-COMMA- |
denotes |
, |
T17884 |
37860-37866 |
NNP |
denotes |
United |
T17885 |
37867-37873 |
NNP |
denotes |
States |
T17886 |
37873-37874 |
-RRB- |
denotes |
) |
T17887 |
37876-37886 |
NN |
denotes |
Objectives |
T17888 |
37887-37891 |
VB |
denotes |
used |
T17889 |
37892-37896 |
VB |
denotes |
were |
T17890 |
37897-37899 |
CD |
denotes |
1× |
T17891 |
37900-37901 |
-LRB- |
denotes |
( |
T17892 |
37901-37903 |
NN |
denotes |
NA |
T17893 |
37904-37905 |
SYM |
denotes |
= |
T17894 |
37906-37910 |
CD |
denotes |
0.04 |
T17895 |
37910-37911 |
-RRB- |
denotes |
) |
T17896 |
37912-37915 |
CC |
denotes |
and |
T17897 |
37916-37919 |
CD |
denotes |
10× |
T17898 |
37920-37921 |
-LRB- |
denotes |
( |
T17899 |
37921-37923 |
NN |
denotes |
NA |
T17900 |
37924-37925 |
SYM |
denotes |
= |
T17901 |
37926-37929 |
CD |
denotes |
0.5 |
T17902 |
37929-37930 |
-RRB- |
denotes |
) |
T17903 |
37932-37938 |
NN |
denotes |
Images |
T17904 |
37939-37943 |
VB |
denotes |
were |
T17905 |
37944-37953 |
VB |
denotes |
processed |
T17906 |
37953-37954 |
-COMMA- |
denotes |
, |
T17907 |
37955-37968 |
VB |
denotes |
pseudocolored |
T17908 |
37968-37969 |
-COMMA- |
denotes |
, |
T17909 |
37970-37973 |
CC |
denotes |
and |
T17910 |
37974-37982 |
VB |
denotes |
combined |
T17911 |
37983-37988 |
VB |
denotes |
using |
T17912 |
37989-37998 |
NNP |
denotes |
Photoshop |
T17913 |
37999-38000 |
-LRB- |
denotes |
( |
T17914 |
38000-38005 |
NNP |
denotes |
Adobe |
T17915 |
38005-38006 |
-COMMA- |
denotes |
, |
T17916 |
38007-38010 |
NNP |
denotes |
San |
T17917 |
38011-38015 |
NNP |
denotes |
Jose |
T17918 |
38015-38016 |
-COMMA- |
denotes |
, |
T17919 |
38017-38027 |
NNP |
denotes |
California |
T17920 |
38027-38028 |
-COMMA- |
denotes |
, |
T17921 |
38029-38035 |
NNP |
denotes |
United |
T17922 |
38036-38042 |
NNP |
denotes |
States |
T17923 |
38042-38043 |
-RRB- |
denotes |
) |
T17924 |
38044-38052 |
NN |
denotes |
software |
T17925 |
38053-38057 |
IN |
denotes |
with |
T17926 |
38058-38063 |
NNP |
denotes |
Fovea |
T17927 |
38064-38067 |
NNP |
denotes |
Pro |
T17928 |
38068-38069 |
-LRB- |
denotes |
( |
T17929 |
38069-38077 |
NNP |
denotes |
Reindeer |
T17930 |
38078-38086 |
NNP |
denotes |
Graphics |
T17931 |
38086-38087 |
-COMMA- |
denotes |
, |
T17932 |
38088-38097 |
NNP |
denotes |
Asheville |
T17933 |
38097-38098 |
-COMMA- |
denotes |
, |
T17934 |
38099-38104 |
NNP |
denotes |
North |
T17935 |
38105-38113 |
NNP |
denotes |
Carolina |
T17936 |
38113-38114 |
-COMMA- |
denotes |
, |
T17937 |
38115-38121 |
NNP |
denotes |
United |
T17938 |
38122-38128 |
NNP |
denotes |
States |
T17939 |
38128-38129 |
-RRB- |
denotes |
) |
T17940 |
38130-38137 |
NN |
denotes |
plugins |
T17941 |
38139-38147 |
JJ |
denotes |
Original |
T17942 |
38148-38154 |
NN |
denotes |
images |
T17943 |
38155-38158 |
VB |
denotes |
are |
T17944 |
38159-38168 |
JJ |
denotes |
available |
T18185 |
38171-38180 |
NNP |
denotes |
Histology |
T18186 |
38182-38190 |
JJ |
denotes |
18.5-dpc |
T18187 |
38191-38198 |
NN |
denotes |
embryos |
T18188 |
38199-38203 |
VB |
denotes |
were |
T18189 |
38204-38217 |
VB |
denotes |
exsanguinated |
T18190 |
38218-38221 |
CC |
denotes |
and |
T18191 |
38222-38232 |
JJ |
denotes |
peripheral |
T18192 |
38233-38238 |
NN |
denotes |
blood |
T18193 |
38239-38245 |
NN |
denotes |
smears |
T18194 |
38246-38250 |
VB |
denotes |
were |
T18195 |
38251-38259 |
VB |
denotes |
prepared |
T18196 |
38260-38264 |
IN |
denotes |
from |
T18197 |
38265-38269 |
CC |
denotes |
both |
T18198 |
38270-38276 |
JJ |
denotes |
mutant |
T18199 |
38277-38280 |
CC |
denotes |
and |
T18200 |
38281-38283 |
JJ |
denotes |
WT |
T18201 |
38284-38288 |
NN |
denotes |
mice |
T18202 |
38290-38293 |
DT |
denotes |
The |
T18203 |
38294-38300 |
NN |
denotes |
slides |
T18204 |
38301-38305 |
VB |
denotes |
were |
T18205 |
38306-38320 |
JJ |
denotes |
Wright-stained |
T18206 |
38321-38324 |
CC |
denotes |
and |
T18207 |
38325-38329 |
VB |
denotes |
read |
T18208 |
38330-38332 |
IN |
denotes |
by |
T18209 |
38333-38336 |
NNP |
denotes |
DAF |
T18210 |
38338-38341 |
IN |
denotes |
For |
T18211 |
38342-38347 |
JJ |
denotes |
whole |
T18212 |
38348-38353 |
NN |
denotes |
mount |
T18213 |
38354-38362 |
NN |
denotes |
analysis |
T18214 |
38362-38363 |
-COMMA- |
denotes |
, |
T18215 |
38364-38372 |
JJ |
denotes |
14.5-dpc |
T18216 |
38373-38375 |
NN |
denotes |
WT |
T18217 |
38376-38379 |
CC |
denotes |
and |
T18218 |
38380-38386 |
JJ |
denotes |
mutant |
T18219 |
38387-38394 |
NN |
denotes |
embryos |
T18220 |
38394-38395 |
-COMMA- |
denotes |
, |
T18221 |
38396-38399 |
CC |
denotes |
and |
T18222 |
38400-38409 |
JJ |
denotes |
postnatal |
T18223 |
38410-38418 |
NN |
denotes |
day–10.5 |
T18224 |
38419-38423 |
NN |
denotes |
mice |
T18225 |
38424-38428 |
VB |
denotes |
were |
T18226 |
38429-38434 |
VB |
denotes |
fixed |
T18227 |
38435-38437 |
IN |
denotes |
in |
T18228 |
38438-38440 |
CD |
denotes |
10 |
T18229 |
38440-38441 |
NN |
denotes |
% |
T18230 |
38442-38450 |
NN |
denotes |
formalin |
T18231 |
38450-38451 |
-COMMA- |
denotes |
, |
T18232 |
38452-38469 |
JJ |
denotes |
paraffin-embedded |
T18233 |
38469-38470 |
-COMMA- |
denotes |
, |
T18234 |
38471-38480 |
VB |
denotes |
sectioned |
T18235 |
38481-38483 |
IN |
denotes |
at |
T18236 |
38484-38485 |
CD |
denotes |
5 |
T18237 |
38486-38488 |
NN |
denotes |
μm |
T18238 |
38488-38489 |
-COMMA- |
denotes |
, |
T18239 |
38490-38493 |
CC |
denotes |
and |
T18240 |
38494-38501 |
VB |
denotes |
stained |
T18241 |
38502-38506 |
IN |
denotes |
with |
T18242 |
38507-38518 |
NN |
denotes |
hematoxylin |
T18243 |
38519-38522 |
CC |
denotes |
and |
T18244 |
38523-38528 |
NN |
denotes |
eosin |
T18245 |
38530-38535 |
NN |
denotes |
Liver |
T18246 |
38536-38543 |
NN |
denotes |
samples |
T18247 |
38544-38545 |
-LRB- |
denotes |
( |
T18248 |
38545-38547 |
IN |
denotes |
at |
T18249 |
38548-38552 |
CD |
denotes |
14.5 |
T18250 |
38553-38556 |
NN |
denotes |
dpc |
T18251 |
38557-38560 |
CC |
denotes |
and |
T18252 |
38561-38565 |
CD |
denotes |
18.5 |
T18253 |
38566-38569 |
NN |
denotes |
dpc |
T18254 |
38569-38570 |
-RRB- |
denotes |
) |
T18255 |
38571-38575 |
VB |
denotes |
were |
T18256 |
38576-38584 |
VB |
denotes |
prepared |
T18257 |
38585-38587 |
IN |
denotes |
in |
T18258 |
38588-38589 |
DT |
denotes |
a |
T18259 |
38590-38597 |
JJ |
denotes |
similar |
T18260 |
38598-38604 |
NN |
denotes |
manner |
T18261 |
38606-38612 |
NN |
denotes |
Images |
T18262 |
38613-38617 |
VB |
denotes |
were |
T18263 |
38618-38626 |
VB |
denotes |
obtained |
T18264 |
38627-38631 |
IN |
denotes |
with |
T18265 |
38632-38637 |
NNP |
denotes |
Nikon |
T18266 |
38638-38648 |
NN |
denotes |
Labophot-2 |
T18267 |
38649-38659 |
NN |
denotes |
microscope |
T18268 |
38661-38671 |
NN |
denotes |
Objectives |
T18269 |
38672-38676 |
VB |
denotes |
used |
T18270 |
38677-38681 |
VB |
denotes |
were |
T18271 |
38682-38683 |
NN |
denotes |
E |
T18272 |
38684-38688 |
NNP |
denotes |
Plan |
T18273 |
38689-38696 |
CD |
denotes |
40/0.65 |
T18274 |
38697-38705 |
CD |
denotes |
160/0.17 |
T18275 |
38706-38711 |
NNP |
denotes |
Nikon |
T18276 |
38712-38713 |
-LRB- |
denotes |
( |
T18277 |
38713-38716 |
CD |
denotes |
40× |
T18278 |
38717-38726 |
NN |
denotes |
objective |
T18279 |
38726-38727 |
-RRB- |
denotes |
) |
T18280 |
38727-38728 |
-COMMA- |
denotes |
, |
T18281 |
38729-38730 |
NN |
denotes |
E |
T18282 |
38731-38735 |
NNP |
denotes |
Plan |
T18283 |
38736-38744 |
CD |
denotes |
100/1.25 |
T18284 |
38745-38748 |
NN |
denotes |
oil |
T18285 |
38749-38757 |
CD |
denotes |
160/0.17 |
T18286 |
38758-38763 |
NNP |
denotes |
Nikon |
T18287 |
38764-38765 |
-LRB- |
denotes |
( |
T18288 |
38765-38769 |
CD |
denotes |
100× |
T18289 |
38770-38779 |
NN |
denotes |
objective |
T18290 |
38779-38780 |
-RRB- |
denotes |
) |
T18291 |
38782-38785 |
DT |
denotes |
The |
T18292 |
38786-38792 |
NN |
denotes |
camera |
T18293 |
38793-38796 |
VB |
denotes |
was |
T18294 |
38797-38798 |
DT |
denotes |
a |
T18295 |
38799-38804 |
NNP |
denotes |
Nikon |
T18296 |
38805-38812 |
NNP |
denotes |
Coolpix |
T18297 |
38813-38817 |
CD |
denotes |
4300 |
T18298 |
38819-38827 |
JJ |
denotes |
Original |
T18299 |
38828-38834 |
NN |
denotes |
images |
T18300 |
38835-38838 |
VB |
denotes |
are |
T18301 |
38839-38848 |
JJ |
denotes |
available |
T18461 |
38851-38859 |
NN |
denotes |
Northern |
T18462 |
38860-38864 |
NN |
denotes |
blot |
T18463 |
38866-38867 |
DT |
denotes |
A |
T18464 |
38868-38873 |
NN |
denotes |
mouse |
T18465 |
38874-38883 |
JJ |
denotes |
embryonic |
T18466 |
38884-38890 |
NN |
denotes |
tissue |
T18467 |
38891-38899 |
NN |
denotes |
Northern |
T18468 |
38900-38904 |
NN |
denotes |
blot |
T18469 |
38905-38911 |
NN |
denotes |
filter |
T18470 |
38912-38913 |
-LRB- |
denotes |
( |
T18471 |
38913-38920 |
NN |
denotes |
Seegene |
T18472 |
38920-38921 |
-COMMA- |
denotes |
, |
T18473 |
38922-38931 |
NNP |
denotes |
Rockville |
T18474 |
38931-38932 |
-COMMA- |
denotes |
, |
T18475 |
38933-38941 |
NNP |
denotes |
Maryland |
T18476 |
38941-38942 |
-COMMA- |
denotes |
, |
T18477 |
38943-38949 |
NNP |
denotes |
United |
T18478 |
38950-38956 |
NNP |
denotes |
States |
T18479 |
38956-38957 |
-RRB- |
denotes |
) |
T18480 |
38958-38961 |
VB |
denotes |
was |
T18481 |
38962-38972 |
VB |
denotes |
hybridized |
T18482 |
38973-38977 |
IN |
denotes |
with |
T18483 |
38978-38979 |
DT |
denotes |
a |
T18484 |
38980-38984 |
NN |
denotes |
Sox6 |
T18485 |
38985-38990 |
NN |
denotes |
probe |
T18486 |
38991-39000 |
VB |
denotes |
generated |
T18487 |
39001-39003 |
IN |
denotes |
by |
T18488 |
39004-39010 |
NN |
denotes |
RT-PCR |
T18489 |
39011-39012 |
-LRB- |
denotes |
( |
T18490 |
39012-39023 |
NN |
denotes |
nucleotides |
T18491 |
39024-39033 |
CD |
denotes |
1353–1927 |
T18492 |
39033-39034 |
-RRB- |
denotes |
) |
T18493 |
39035-39038 |
CC |
denotes |
and |
T18494 |
39039-39046 |
VB |
denotes |
labeled |
T18495 |
39047-39051 |
IN |
denotes |
with |
T18496 |
39052-39053 |
-LRB- |
denotes |
[ |
T18497 |
39053-39058 |
NN |
denotes |
α-32P |
T18498 |
39058-39059 |
-RRB- |
denotes |
] |
T18499 |
39059-39063 |
NN |
denotes |
dCTP |
T18500 |
39063-39064 |
-COMMA- |
denotes |
, |
T18501 |
39065-39067 |
IN |
denotes |
by |
T18502 |
39068-39074 |
JJ |
denotes |
random |
T18503 |
39075-39081 |
NN |
denotes |
primer |
T18504 |
39082-39090 |
NN |
denotes |
labeling |
T18505 |
39091-39092 |
-LRB- |
denotes |
( |
T18506 |
39092-39103 |
NN |
denotes |
RediprimeII |
T18507 |
39103-39104 |
-COLON- |
denotes |
; |
T18508 |
39105-39113 |
NNP |
denotes |
Amersham |
T18509 |
39114-39125 |
NNP |
denotes |
Biosciences |
T18510 |
39125-39126 |
-COMMA- |
denotes |
, |
T18511 |
39127-39142 |
NNP |
denotes |
Buckinghamshire |
T18512 |
39142-39143 |
-COMMA- |
denotes |
, |
T18513 |
39144-39151 |
NNP |
denotes |
England |
T18514 |
39151-39152 |
-COMMA- |
denotes |
, |
T18515 |
39153-39159 |
NNP |
denotes |
United |
T18516 |
39160-39167 |
NNP |
denotes |
Kingdom |
T18517 |
39167-39168 |
-RRB- |
denotes |
) |
T18518 |
39170-39173 |
DT |
denotes |
The |
T18519 |
39174-39187 |
NN |
denotes |
hybridization |
T18520 |
39188-39191 |
VB |
denotes |
was |
T18521 |
39192-39201 |
VB |
denotes |
performed |
T18522 |
39202-39204 |
IN |
denotes |
in |
T18523 |
39205-39214 |
NN |
denotes |
phosphate |
T18524 |
39215-39223 |
VB |
denotes |
buffered |
T18525 |
39224-39225 |
CD |
denotes |
7 |
T18526 |
39225-39226 |
NN |
denotes |
% |
T18527 |
39227-39230 |
NN |
denotes |
SDS |
T18528 |
39231-39244 |
NN |
denotes |
hybridization |
T18529 |
39245-39253 |
NN |
denotes |
solution |
T18530 |
39255-39260 |
NN |
denotes |
Blots |
T18531 |
39261-39265 |
VB |
denotes |
were |
T18532 |
39266-39272 |
VB |
denotes |
washed |
T18533 |
39273-39277 |
IN |
denotes |
with |
T18534 |
39278-39282 |
CD |
denotes |
0.2× |
T18535 |
39283-39286 |
NNP |
denotes |
SSC |
T18536 |
39286-39287 |
-COMMA- |
denotes |
, |
T18537 |
39288-39289 |
CD |
denotes |
1 |
T18538 |
39289-39290 |
NN |
denotes |
% |
T18539 |
39291-39294 |
NN |
denotes |
SDS |
T18540 |
39295-39297 |
IN |
denotes |
at |
T18541 |
39298-39300 |
CD |
denotes |
60 |
T18542 |
39301-39303 |
NN |
denotes |
°C |
T18543 |
39304-39309 |
JJ |
denotes |
prior |
T18544 |
39310-39312 |
TO |
denotes |
to |
T18545 |
39313-39321 |
NN |
denotes |
exposure |
T18546 |
39322-39324 |
TO |
denotes |
to |
T18547 |
39325-39330 |
NN |
denotes |
X-ray |
T18548 |
39331-39335 |
NN |
denotes |
film |
T18549 |
39336-39337 |
-LRB- |
denotes |
( |
T18550 |
39337-39342 |
NNP |
denotes |
Kodak |
T18551 |
39342-39343 |
-COMMA- |
denotes |
, |
T18552 |
39344-39353 |
NNP |
denotes |
Rochester |
T18553 |
39353-39354 |
-COMMA- |
denotes |
, |
T18554 |
39355-39358 |
NNP |
denotes |
New |
T18555 |
39359-39363 |
NNP |
denotes |
York |
T18556 |
39363-39364 |
-COMMA- |
denotes |
, |
T18557 |
39365-39371 |
NNP |
denotes |
United |
T18558 |
39372-39378 |
NNP |
denotes |
States |
T18559 |
39378-39379 |
-RRB- |
denotes |
) |
T18560 |
39380-39382 |
IN |
denotes |
at |
T18561 |
39383-39386 |
CD |
denotes |
−80 |
T18562 |
39387-39389 |
NN |
denotes |
°C |
T18563 |
39390-39393 |
IN |
denotes |
for |
T18564 |
39394-39395 |
CD |
denotes |
6 |
T18565 |
39396-39397 |
NN |
denotes |
d |
T18723 |
39400-39404 |
NN |
denotes |
Cell |
T18724 |
39405-39412 |
NN |
denotes |
culture |
T18725 |
39413-39416 |
CC |
denotes |
and |
T18726 |
39417-39429 |
NN |
denotes |
transfection |
T18727 |
39431-39436 |
NN |
denotes |
GM979 |
T18728 |
39437-39442 |
NN |
denotes |
cells |
T18729 |
39443-39444 |
-LRB- |
denotes |
( |
T18730 |
39444-39451 |
NNP |
denotes |
Coriell |
T18731 |
39452-39456 |
NNP |
denotes |
Cell |
T18732 |
39457-39469 |
NNP |
denotes |
Repositories |
T18733 |
39469-39470 |
-COMMA- |
denotes |
, |
T18734 |
39471-39477 |
NNP |
denotes |
Camden |
T18735 |
39477-39478 |
-COMMA- |
denotes |
, |
T18736 |
39479-39482 |
NNP |
denotes |
New |
T18737 |
39483-39489 |
NNP |
denotes |
Jersey |
T18738 |
39489-39490 |
-COMMA- |
denotes |
, |
T18739 |
39491-39497 |
NNP |
denotes |
United |
T18740 |
39498-39504 |
NNP |
denotes |
States |
T18741 |
39504-39505 |
-RRB- |
denotes |
) |
T18742 |
39506-39510 |
VB |
denotes |
were |
T18743 |
39511-39519 |
VB |
denotes |
cultured |
T18744 |
39520-39522 |
IN |
denotes |
in |
T18745 |
39523-39526 |
NNP |
denotes |
Ham |
T18746 |
39526-39528 |
POS |
denotes |
's |
T18747 |
39529-39532 |
NN |
denotes |
F12 |
T18748 |
39533-39537 |
IN |
denotes |
with |
T18749 |
39538-39539 |
CD |
denotes |
2 |
T18750 |
39540-39542 |
NN |
denotes |
mM |
T18751 |
39543-39554 |
NN |
denotes |
L-glutamine |
T18752 |
39555-39567 |
VB |
denotes |
supplemented |
T18753 |
39568-39572 |
IN |
denotes |
with |
T18754 |
39573-39589 |
JJ |
denotes |
heat-inactivated |
T18755 |
39590-39592 |
CD |
denotes |
10 |
T18756 |
39592-39593 |
NN |
denotes |
% |
T18757 |
39594-39599 |
JJ |
denotes |
fetal |
T18758 |
39600-39604 |
NN |
denotes |
calf |
T18759 |
39605-39610 |
NN |
denotes |
serum |
T18760 |
39611-39612 |
-LRB- |
denotes |
( |
T18761 |
39612-39621 |
NN |
denotes |
Ivitrogen |
T18762 |
39621-39622 |
-COMMA- |
denotes |
, |
T18763 |
39623-39631 |
NNP |
denotes |
Carlsbad |
T18764 |
39631-39632 |
-COMMA- |
denotes |
, |
T18765 |
39633-39643 |
NNP |
denotes |
California |
T18766 |
39643-39644 |
-COMMA- |
denotes |
, |
T18767 |
39645-39651 |
NNP |
denotes |
United |
T18768 |
39652-39658 |
NNP |
denotes |
States |
T18769 |
39658-39659 |
-RRB- |
denotes |
) |
T18770 |
39659-39660 |
-COMMA- |
denotes |
, |
T18771 |
39661-39671 |
NN |
denotes |
penicillin |
T18772 |
39672-39673 |
-LRB- |
denotes |
( |
T18773 |
39673-39676 |
CD |
denotes |
100 |
T18774 |
39677-39685 |
NN |
denotes |
units/ml |
T18775 |
39685-39686 |
-RRB- |
denotes |
) |
T18776 |
39686-39687 |
-COMMA- |
denotes |
, |
T18777 |
39688-39700 |
NN |
denotes |
streptomycin |
T18778 |
39701-39704 |
CD |
denotes |
100 |
T18779 |
39705-39710 |
NN |
denotes |
μg/ml |
T18780 |
39710-39711 |
-RRB- |
denotes |
) |
T18781 |
39711-39712 |
-COMMA- |
denotes |
, |
T18782 |
39713-39716 |
CC |
denotes |
and |
T18783 |
39717-39728 |
NN |
denotes |
L-glutamine |
T18784 |
39729-39730 |
-LRB- |
denotes |
( |
T18785 |
39730-39731 |
CD |
denotes |
2 |
T18786 |
39732-39734 |
NN |
denotes |
mM |
T18787 |
39734-39735 |
-RRB- |
denotes |
) |
T18788 |
39737-39740 |
NN |
denotes |
MEL |
T18789 |
39741-39746 |
NN |
denotes |
cells |
T18790 |
39747-39751 |
VB |
denotes |
were |
T18791 |
39752-39760 |
VB |
denotes |
cultured |
T18792 |
39761-39763 |
IN |
denotes |
in |
T18793 |
39764-39768 |
NN |
denotes |
DMEM |
T18794 |
39769-39781 |
VB |
denotes |
supplemented |
T18795 |
39782-39784 |
IN |
denotes |
as |
T18796 |
39785-39790 |
JJ |
denotes |
above |
T18797 |
39791-39792 |
-LRB- |
denotes |
( |
T18798 |
39792-39799 |
IN |
denotes |
without |
T18799 |
39800-39804 |
NN |
denotes |
heat |
T18800 |
39805-39817 |
VB |
denotes |
inactivating |
T18801 |
39818-39821 |
DT |
denotes |
the |
T18802 |
39822-39827 |
NN |
denotes |
serum |
T18803 |
39827-39828 |
-RRB- |
denotes |
) |
T18804 |
39830-39835 |
NN |
denotes |
GM979 |
T18805 |
39836-39841 |
NN |
denotes |
cells |
T18806 |
39842-39843 |
-LRB- |
denotes |
( |
T18807 |
39843-39844 |
CD |
denotes |
4 |
T18808 |
39845-39846 |
NN |
denotes |
× |
T18809 |
39847-39850 |
CD |
denotes |
105 |
T18810 |
39850-39851 |
-RRB- |
denotes |
) |
T18811 |
39852-39854 |
IN |
denotes |
in |
T18812 |
39855-39858 |
NN |
denotes |
log |
T18813 |
39859-39864 |
NN |
denotes |
phase |
T18814 |
39865-39867 |
IN |
denotes |
of |
T18815 |
39868-39874 |
NN |
denotes |
growth |
T18816 |
39875-39879 |
VB |
denotes |
were |
T18817 |
39880-39891 |
VB |
denotes |
transfected |
T18818 |
39892-39896 |
IN |
denotes |
with |
T18819 |
39897-39905 |
NN |
denotes |
plasmids |
T18820 |
39906-39908 |
IN |
denotes |
by |
T18821 |
39909-39916 |
NN |
denotes |
FuGENE6 |
T18822 |
39917-39918 |
-LRB- |
denotes |
( |
T18823 |
39918-39923 |
NNP |
denotes |
Roche |
T18824 |
39923-39924 |
-COMMA- |
denotes |
, |
T18825 |
39925-39937 |
NNP |
denotes |
Indianapolis |
T18826 |
39937-39938 |
-COMMA- |
denotes |
, |
T18827 |
39939-39946 |
NNP |
denotes |
Indiana |
T18828 |
39946-39947 |
-COMMA- |
denotes |
, |
T18829 |
39948-39954 |
NNP |
denotes |
United |
T18830 |
39955-39961 |
NNP |
denotes |
States |
T18831 |
39961-39962 |
-RRB- |
denotes |
) |
T18832 |
39964-39969 |
NN |
denotes |
Cells |
T18833 |
39970-39974 |
VB |
denotes |
were |
T18834 |
39975-39986 |
VB |
denotes |
transfected |
T18835 |
39987-39991 |
IN |
denotes |
with |
T18836 |
39992-39994 |
JJ |
denotes |
ɛy |
T18837 |
39995-40003 |
NN |
denotes |
promoter |
T18838 |
40004-40012 |
NN |
denotes |
reporter |
T18839 |
40013-40023 |
NN |
denotes |
constructs |
T18840 |
40024-40025 |
-LRB- |
denotes |
( |
T18841 |
40025-40028 |
CD |
denotes |
500 |
T18842 |
40029-40031 |
NN |
denotes |
ng |
T18843 |
40031-40032 |
-RRB- |
denotes |
) |
T18844 |
40033-40038 |
IN |
denotes |
along |
T18845 |
40039-40043 |
IN |
denotes |
with |
T18846 |
40044-40050 |
CC |
denotes |
either |
T18847 |
40051-40056 |
JJ |
denotes |
empty |
T18848 |
40057-40063 |
NN |
denotes |
vector |
T18849 |
40064-40066 |
CC |
denotes |
or |
T18850 |
40067-40071 |
NN |
denotes |
Sox6 |
T18851 |
40072-40086 |
NN |
denotes |
overexpression |
T18852 |
40087-40093 |
NN |
denotes |
vector |
T18853 |
40094-40095 |
-LRB- |
denotes |
( |
T18854 |
40095-40099 |
CD |
denotes |
1000 |
T18855 |
40100-40102 |
NN |
denotes |
ng |
T18856 |
40102-40103 |
-RRB- |
denotes |
) |
T18857 |
40105-40107 |
IN |
denotes |
In |
T18858 |
40108-40114 |
NN |
denotes |
assays |
T18859 |
40115-40117 |
IN |
denotes |
of |
T18860 |
40118-40124 |
NN |
denotes |
dosage |
T18861 |
40125-40131 |
NN |
denotes |
effect |
T18862 |
40131-40132 |
-COMMA- |
denotes |
, |
T18863 |
40133-40135 |
PRP |
denotes |
we |
T18864 |
40136-40140 |
VB |
denotes |
used |
T18865 |
40141-40144 |
CD |
denotes |
200 |
T18866 |
40145-40147 |
NN |
denotes |
ng |
T18867 |
40147-40148 |
-COMMA- |
denotes |
, |
T18868 |
40149-40152 |
CD |
denotes |
500 |
T18869 |
40153-40155 |
NN |
denotes |
ng |
T18870 |
40155-40156 |
-COMMA- |
denotes |
, |
T18871 |
40157-40160 |
CC |
denotes |
and |
T18872 |
40161-40165 |
CD |
denotes |
1000 |
T18873 |
40166-40168 |
NN |
denotes |
ng |
T18874 |
40168-40169 |
-RRB- |
denotes |
) |
T18875 |
40169-40176 |
NN |
denotes |
. pRL-C |
T18876 |
40176-40180 |
NN |
denotes |
MV 1 |
T18877 |
40180-40181 |
-LRB- |
denotes |
5 |
T18878 |
40181-40188 |
NN |
denotes |
ng (Pro |
T18879 |
40188-40189 |
-RRB- |
denotes |
m |
T18880 |
40189-40192 |
VB |
denotes |
ega |
T18881 |
40192-40196 |
VB |
denotes |
) wa |
T18882 |
40196-40198 |
IN |
denotes |
s |
T18883 |
40198-40199 |
DT |
denotes |
u |
T18884 |
40199-40206 |
NN |
denotes |
sed as |
T18885 |
40206-40209 |
IN |
denotes |
a c |
T18886 |
40209-40221 |
NN |
denotes |
ontrol for t |
T18887 |
40221-40231 |
NN |
denotes |
ransfectio |
T19150 |
40246-40253 |
JJ |
denotes |
Nuclear |
T19151 |
40254-40261 |
NN |
denotes |
protein |
T19152 |
40262-40269 |
NN |
denotes |
extract |
T19153 |
40270-40273 |
CC |
denotes |
and |
T19154 |
40274-40276 |
FW |
denotes |
in |
T19155 |
40277-40282 |
FW |
denotes |
vitro |
T19156 |
40283-40294 |
NN |
denotes |
translation |
T19157 |
40295-40297 |
IN |
denotes |
of |
T19158 |
40298-40302 |
NN |
denotes |
Sox6 |
T19159 |
40304-40311 |
JJ |
denotes |
Nuclear |
T19160 |
40312-40320 |
NN |
denotes |
extracts |
T19161 |
40321-40325 |
VB |
denotes |
were |
T19162 |
40326-40334 |
VB |
denotes |
prepared |
T19163 |
40335-40339 |
IN |
denotes |
from |
T19164 |
40340-40343 |
NN |
denotes |
MEL |
T19165 |
40344-40349 |
NN |
denotes |
cells |
T19166 |
40350-40351 |
-LRB- |
denotes |
( |
T19167 |
40351-40352 |
CD |
denotes |
2 |
T19168 |
40353-40354 |
CC |
denotes |
× |
T19169 |
40355-40358 |
CD |
denotes |
107 |
T19170 |
40358-40359 |
-RRB- |
denotes |
) |
T19171 |
40360-40365 |
VB |
denotes |
using |
T19172 |
40366-40367 |
DT |
denotes |
a |
T19173 |
40368-40371 |
NN |
denotes |
kit |
T19174 |
40372-40373 |
-LRB- |
denotes |
( |
T19175 |
40373-40379 |
JJ |
denotes |
Active |
T19176 |
40380-40385 |
NNP |
denotes |
Motif |
T19177 |
40385-40386 |
-COMMA- |
denotes |
, |
T19178 |
40387-40395 |
NNP |
denotes |
Carlsbad |
T19179 |
40395-40396 |
-COMMA- |
denotes |
, |
T19180 |
40397-40407 |
NNP |
denotes |
California |
T19181 |
40407-40408 |
-COMMA- |
denotes |
, |
T19182 |
40409-40415 |
NNP |
denotes |
United |
T19183 |
40416-40422 |
NNP |
denotes |
States |
T19184 |
40422-40423 |
-RRB- |
denotes |
) |
T19185 |
40425-40428 |
DT |
denotes |
The |
T19186 |
40429-40433 |
NN |
denotes |
Sox6 |
T19187 |
40434-40436 |
FW |
denotes |
in |
T19188 |
40437-40442 |
FW |
denotes |
vitro |
T19189 |
40443-40454 |
NN |
denotes |
translation |
T19190 |
40455-40465 |
NN |
denotes |
expression |
T19191 |
40466-40472 |
NN |
denotes |
vector |
T19192 |
40472-40473 |
-COMMA- |
denotes |
, |
T19193 |
40474-40480 |
VB |
denotes |
tagged |
T19194 |
40481-40485 |
IN |
denotes |
with |
T19195 |
40486-40491 |
NN |
denotes |
c-Myc |
T19196 |
40492-40495 |
CC |
denotes |
and |
T19197 |
40496-40498 |
NN |
denotes |
HA |
T19198 |
40498-40499 |
-COMMA- |
denotes |
, |
T19199 |
40500-40503 |
VB |
denotes |
was |
T19200 |
40504-40513 |
VB |
denotes |
described |
T19201 |
40514-40520 |
IN |
denotes |
before |
T19202 |
40521-40522 |
-LRB- |
denotes |
[ |
T19203 |
40522-40524 |
CD |
denotes |
15 |
T19204 |
40524-40525 |
-RRB- |
denotes |
] |
T19205 |
40527-40530 |
DT |
denotes |
The |
T19206 |
40531-40542 |
NN |
denotes |
translation |
T19207 |
40543-40546 |
VB |
denotes |
was |
T19208 |
40547-40556 |
VB |
denotes |
performed |
T19209 |
40557-40559 |
IN |
denotes |
in |
T19210 |
40560-40561 |
DT |
denotes |
a |
T19211 |
40562-40574 |
NN |
denotes |
reticulocyte |
T19212 |
40575-40581 |
NN |
denotes |
lysate |
T19213 |
40582-40587 |
VB |
denotes |
based |
T19214 |
40588-40590 |
FW |
denotes |
in |
T19215 |
40591-40596 |
FW |
denotes |
vitro |
T19216 |
40597-40610 |
JJ |
denotes |
translational |
T19217 |
40611-40617 |
NN |
denotes |
system |
T19218 |
40618-40619 |
-LRB- |
denotes |
( |
T19219 |
40619-40623 |
NNP |
denotes |
TNT® |
T19220 |
40624-40629 |
NNP |
denotes |
Quick |
T19221 |
40630-40637 |
NNP |
denotes |
Coupled |
T19222 |
40638-40663 |
NNP |
denotes |
Transcription/Translation |
T19223 |
40664-40671 |
NNP |
denotes |
Systems |
T19224 |
40671-40672 |
-COMMA- |
denotes |
, |
T19225 |
40673-40680 |
NNP |
denotes |
Promega |
T19226 |
40680-40681 |
-RRB- |
denotes |
) |
T19227 |
40683-40684 |
DT |
denotes |
A |
T19228 |
40685-40691 |
NN |
denotes |
vector |
T19229 |
40692-40699 |
IN |
denotes |
without |
T19230 |
40700-40703 |
DT |
denotes |
the |
T19231 |
40704-40708 |
NN |
denotes |
Sox6 |
T19232 |
40709-40715 |
NN |
denotes |
coding |
T19233 |
40716-40724 |
NN |
denotes |
sequence |
T19234 |
40725-40728 |
VB |
denotes |
was |
T19235 |
40729-40733 |
RB |
denotes |
also |
T19236 |
40734-40744 |
VB |
denotes |
translated |
T19237 |
40745-40747 |
IN |
denotes |
as |
T19238 |
40748-40749 |
DT |
denotes |
a |
T19239 |
40750-40758 |
JJ |
denotes |
negative |
T19240 |
40759-40766 |
NN |
denotes |
control |
T19427 |
40769-40779 |
NN |
denotes |
Antibodies |
T19428 |
40781-40785 |
NN |
denotes |
Sox6 |
T19429 |
40786-40796 |
NN |
denotes |
antibodies |
T19430 |
40797-40801 |
VB |
denotes |
used |
T19431 |
40802-40804 |
IN |
denotes |
in |
T19432 |
40805-40809 |
DT |
denotes |
this |
T19433 |
40810-40815 |
NN |
denotes |
study |
T19434 |
40816-40820 |
VB |
denotes |
were |
T19435 |
40821-40827 |
CC |
denotes |
either |
T19436 |
40828-40834 |
RB |
denotes |
kindly |
T19437 |
40835-40843 |
VB |
denotes |
provided |
T19438 |
40844-40846 |
IN |
denotes |
by |
T19439 |
40847-40850 |
NNP |
denotes |
Dr. |
T19440 |
40851-40855 |
NNP |
denotes |
Enzo |
T19441 |
40856-40861 |
NNP |
denotes |
Lalli |
T19442 |
40862-40863 |
-LRB- |
denotes |
( |
T19443 |
40863-40873 |
NNP |
denotes |
Université |
T19444 |
40874-40879 |
NNP |
denotes |
Louis |
T19445 |
40880-40887 |
NNP |
denotes |
Pasteur |
T19446 |
40887-40888 |
-COMMA- |
denotes |
, |
T19447 |
40889-40895 |
NNP |
denotes |
France |
T19448 |
40896-40897 |
-LRB- |
denotes |
[ |
T19449 |
40897-40898 |
CD |
denotes |
7 |
T19450 |
40898-40899 |
-RRB- |
denotes |
] |
T19451 |
40899-40900 |
-RRB- |
denotes |
) |
T19452 |
40901-40903 |
CC |
denotes |
or |
T19453 |
40904-40916 |
RB |
denotes |
commercially |
T19454 |
40917-40925 |
VB |
denotes |
obtained |
T19455 |
40926-40927 |
-LRB- |
denotes |
( |
T19456 |
40927-40934 |
NNP |
denotes |
Catalog |
T19457 |
40935-40938 |
NN |
denotes |
No. |
T19458 |
40939-40947 |
NN |
denotes |
sc-17332 |
T19459 |
40948-40949 |
NNP |
denotes |
X |
T19460 |
40949-40950 |
-COMMA- |
denotes |
, |
T19461 |
40951-40956 |
NNP |
denotes |
Santa |
T19462 |
40957-40961 |
NNP |
denotes |
Cruz |
T19463 |
40962-40975 |
NNP |
denotes |
Biotechnology |
T19464 |
40975-40976 |
-COMMA- |
denotes |
, |
T19465 |
40977-40982 |
NNP |
denotes |
Santa |
T19466 |
40983-40987 |
NNP |
denotes |
Cruz |
T19467 |
40987-40988 |
-COMMA- |
denotes |
, |
T19468 |
40989-40999 |
NNP |
denotes |
California |
T19469 |
40999-41000 |
-COMMA- |
denotes |
, |
T19470 |
41001-41007 |
NNP |
denotes |
United |
T19471 |
41008-41014 |
NNP |
denotes |
States |
T19472 |
41014-41015 |
-RRB- |
denotes |
) |
T19473 |
41017-41020 |
DT |
denotes |
All |
T19474 |
41021-41025 |
NN |
denotes |
Sox6 |
T19475 |
41026-41036 |
NN |
denotes |
antibodies |
T19476 |
41037-41046 |
VB |
denotes |
generated |
T19477 |
41047-41054 |
JJ |
denotes |
similar |
T19478 |
41055-41063 |
JJ |
denotes |
results. |
T19479 |
41064-41069 |
NN |
denotes |
c-Myc |
T19480 |
41070-41078 |
NN |
denotes |
antibody |
T19481 |
41079-41082 |
VB |
denotes |
was |
T19482 |
41083-41092 |
VB |
denotes |
purchased |
T19483 |
41093-41097 |
IN |
denotes |
from |
T19484 |
41098-41109 |
NNP |
denotes |
Invitrogen. |
T19485 |
41110-41116 |
NNP |
denotes |
Normal |
T19486 |
41117-41123 |
NN |
denotes |
rabbit |
T19487 |
41124-41127 |
NN |
denotes |
IgG |
T19488 |
41128-41136 |
NN |
denotes |
antibody |
T19489 |
41137-41140 |
VB |
denotes |
was |
T19490 |
41141-41149 |
VB |
denotes |
obtained |
T19491 |
41150-41154 |
IN |
denotes |
from |
T19492 |
41155-41162 |
NNP |
denotes |
Upstate |
T19493 |
41163-41176 |
NNP |
denotes |
Biotechnology |
T19494 |
41177-41178 |
-LRB- |
denotes |
( |
T19495 |
41178-41182 |
NNP |
denotes |
Lake |
T19496 |
41183-41189 |
NNP |
denotes |
Placid |
T19497 |
41189-41190 |
-COMMA- |
denotes |
, |
T19498 |
41191-41194 |
NNP |
denotes |
New |
T19499 |
41195-41199 |
NNP |
denotes |
York |
T19500 |
41199-41200 |
-COMMA- |
denotes |
, |
T19501 |
41201-41207 |
NNP |
denotes |
United |
T19502 |
41208-41214 |
NNP |
denotes |
States |
T19503 |
41214-41215 |
-RRB- |
denotes |
) |
T19694 |
41218-41222 |
NN |
denotes |
EMSA |
T19695 |
41224-41239 |
JJ |
denotes |
Single-stranded |
T19696 |
41240-41253 |
JJ |
denotes |
complementary |
T19697 |
41254-41270 |
NN |
denotes |
oligonucleotides |
T19698 |
41271-41275 |
VB |
denotes |
were |
T19699 |
41276-41284 |
VB |
denotes |
annealed |
T19700 |
41285-41288 |
CC |
denotes |
and |
T19701 |
41289-41300 |
VB |
denotes |
end-labeled |
T19702 |
41301-41305 |
IN |
denotes |
with |
T19703 |
41306-41307 |
-LRB- |
denotes |
[ |
T19704 |
41307-41312 |
NN |
denotes |
γ-32P |
T19705 |
41312-41313 |
-RRB- |
denotes |
] |
T19706 |
41314-41317 |
NN |
denotes |
ATP |
T19707 |
41318-41322 |
IN |
denotes |
with |
T19708 |
41323-41325 |
NN |
denotes |
T4 |
T19709 |
41326-41340 |
NN |
denotes |
polynucleotide |
T19710 |
41341-41347 |
NN |
denotes |
kinase |
T19711 |
41349-41353 |
NN |
denotes |
EMSA |
T19712 |
41354-41357 |
VB |
denotes |
was |
T19713 |
41358-41367 |
VB |
denotes |
performed |
T19714 |
41368-41372 |
IN |
denotes |
with |
T19715 |
41373-41374 |
CD |
denotes |
5 |
T19716 |
41375-41377 |
NN |
denotes |
μg |
T19717 |
41378-41380 |
IN |
denotes |
of |
T19718 |
41381-41388 |
JJ |
denotes |
nuclear |
T19719 |
41389-41397 |
NN |
denotes |
proteins |
T19720 |
41398-41402 |
IN |
denotes |
from |
T19721 |
41403-41406 |
NN |
denotes |
MEL |
T19722 |
41407-41412 |
NN |
denotes |
cells |
T19723 |
41413-41415 |
CC |
denotes |
or |
T19724 |
41416-41417 |
CD |
denotes |
3 |
T19725 |
41418-41420 |
NN |
denotes |
μl |
T19726 |
41421-41423 |
IN |
denotes |
of |
T19727 |
41424-41426 |
FW |
denotes |
in |
T19728 |
41427-41443 |
JJ |
denotes |
vitro-translated |
T19729 |
41444-41448 |
NN |
denotes |
Sox6 |
T19730 |
41449-41454 |
IN |
denotes |
along |
T19731 |
41455-41459 |
IN |
denotes |
with |
T19732 |
41460-41463 |
DT |
denotes |
the |
T19733 |
41464-41476 |
NN |
denotes |
reticulocyte |
T19734 |
41477-41483 |
NN |
denotes |
lysate |
T19735 |
41484-41486 |
IN |
denotes |
in |
T19736 |
41487-41494 |
NN |
denotes |
binding |
T19737 |
41495-41501 |
NN |
denotes |
buffer |
T19738 |
41501-41502 |
-COLON- |
denotes |
: |
T19739 |
41503-41506 |
CD |
denotes |
100 |
T19740 |
41507-41509 |
NN |
denotes |
mM |
T19741 |
41510-41514 |
NN |
denotes |
NaCl |
T19742 |
41514-41515 |
-COMMA- |
denotes |
, |
T19743 |
41516-41518 |
CD |
denotes |
10 |
T19744 |
41518-41519 |
NN |
denotes |
% |
T19745 |
41520-41528 |
NN |
denotes |
glycerol |
T19746 |
41528-41529 |
-COMMA- |
denotes |
, |
T19747 |
41530-41533 |
CD |
denotes |
200 |
T19748 |
41534-41539 |
NN |
denotes |
ng/μl |
T19749 |
41540-41543 |
NN |
denotes |
BSA |
T19750 |
41543-41544 |
-COMMA- |
denotes |
, |
T19751 |
41545-41547 |
CD |
denotes |
50 |
T19752 |
41548-41553 |
NN |
denotes |
ng/μl |
T19753 |
41554-41558 |
NN |
denotes |
poly |
T19754 |
41559-41560 |
-LRB- |
denotes |
( |
T19755 |
41560-41565 |
NN |
denotes |
dI-dC |
T19756 |
41565-41566 |
-RRB- |
denotes |
) |
T19757 |
41567-41569 |
CC |
denotes |
or |
T19758 |
41570-41574 |
NN |
denotes |
poly |
T19759 |
41575-41576 |
-LRB- |
denotes |
( |
T19760 |
41576-41581 |
NN |
denotes |
dG-dC |
T19761 |
41581-41582 |
-RRB- |
denotes |
) |
T19762 |
41582-41583 |
-COMMA- |
denotes |
, |
T19763 |
41584-41586 |
CD |
denotes |
10 |
T19764 |
41587-41589 |
NN |
denotes |
mM |
T19765 |
41590-41595 |
NN |
denotes |
HEPES |
T19766 |
41596-41597 |
-LRB- |
denotes |
( |
T19767 |
41597-41599 |
NN |
denotes |
pH |
T19768 |
41600-41601 |
CD |
denotes |
7 |
T19769 |
41601-41602 |
-RRB- |
denotes |
) |
T19770 |
41602-41603 |
-COMMA- |
denotes |
, |
T19771 |
41604-41607 |
CD |
denotes |
0.1 |
T19772 |
41608-41610 |
NN |
denotes |
mM |
T19773 |
41611-41615 |
NN |
denotes |
EDTA |
T19774 |
41615-41616 |
-COMMA- |
denotes |
, |
T19775 |
41617-41621 |
CD |
denotes |
0.25 |
T19776 |
41622-41624 |
NN |
denotes |
mM |
T19777 |
41625-41628 |
NN |
denotes |
DTT |
T19778 |
41628-41629 |
-COMMA- |
denotes |
, |
T19779 |
41630-41633 |
CD |
denotes |
0.6 |
T19780 |
41634-41636 |
NN |
denotes |
mM |
T19781 |
41637-41642 |
NN |
denotes |
MgCl2 |
T19782 |
41644-41647 |
IN |
denotes |
For |
T19783 |
41648-41659 |
NN |
denotes |
competition |
T19784 |
41660-41662 |
CC |
denotes |
or |
T19785 |
41663-41673 |
NN |
denotes |
supershift |
T19786 |
41674-41680 |
NN |
denotes |
assays |
T19787 |
41680-41681 |
-COMMA- |
denotes |
, |
T19788 |
41682-41685 |
DT |
denotes |
the |
T19789 |
41686-41695 |
VB |
denotes |
indicated |
T19790 |
41696-41706 |
JJ |
denotes |
unlabelled |
T19791 |
41707-41722 |
NN |
denotes |
oligonucleotide |
T19792 |
41723-41733 |
NN |
denotes |
competitor |
T19793 |
41734-41735 |
-LRB- |
denotes |
( |
T19794 |
41735-41743 |
JJ |
denotes |
200-fold |
T19795 |
41744-41749 |
JJ |
denotes |
molar |
T19796 |
41750-41756 |
NN |
denotes |
excess |
T19797 |
41756-41757 |
-RRB- |
denotes |
) |
T19798 |
41758-41760 |
CC |
denotes |
or |
T19799 |
41761-41769 |
NN |
denotes |
antibody |
T19800 |
41770-41771 |
-LRB- |
denotes |
( |
T19801 |
41771-41772 |
CD |
denotes |
3 |
T19802 |
41773-41775 |
NN |
denotes |
μl |
T19803 |
41775-41776 |
-RRB- |
denotes |
) |
T19804 |
41777-41780 |
VB |
denotes |
was |
T19805 |
41781-41786 |
VB |
denotes |
added |
T19806 |
41787-41789 |
CD |
denotes |
30 |
T19807 |
41790-41793 |
NN |
denotes |
min |
T19808 |
41794-41796 |
TO |
denotes |
to |
T19809 |
41797-41799 |
CD |
denotes |
60 |
T19810 |
41800-41803 |
NN |
denotes |
min |
T19811 |
41804-41809 |
JJ |
denotes |
prior |
T19812 |
41810-41812 |
TO |
denotes |
to |
T19813 |
41813-41821 |
NN |
denotes |
addition |
T19814 |
41822-41824 |
IN |
denotes |
of |
T19815 |
41825-41837 |
VB |
denotes |
radiolabeled |
T19816 |
41838-41843 |
NN |
denotes |
probe |
T19817 |
41845-41854 |
VB |
denotes |
Following |
T19818 |
41855-41863 |
NN |
denotes |
addition |
T19819 |
41864-41866 |
IN |
denotes |
of |
T19820 |
41867-41870 |
DT |
denotes |
the |
T19821 |
41871-41883 |
VB |
denotes |
radiolabeled |
T19822 |
41884-41889 |
NN |
denotes |
probe |
T19823 |
41889-41890 |
-COMMA- |
denotes |
, |
T19824 |
41891-41894 |
DT |
denotes |
the |
T19825 |
41895-41902 |
NN |
denotes |
samples |
T19826 |
41903-41907 |
VB |
denotes |
were |
T19827 |
41908-41917 |
VB |
denotes |
incubated |
T19828 |
41918-41921 |
IN |
denotes |
for |
T19829 |
41922-41924 |
CD |
denotes |
30 |
T19830 |
41925-41928 |
NN |
denotes |
min |
T19831 |
41929-41931 |
CC |
denotes |
or |
T19832 |
41932-41934 |
CD |
denotes |
60 |
T19833 |
41935-41938 |
NN |
denotes |
min |
T19834 |
41939-41941 |
IN |
denotes |
at |
T19835 |
41942-41946 |
NN |
denotes |
room |
T19836 |
41947-41958 |
NN |
denotes |
temperature |
T19837 |
41959-41962 |
CC |
denotes |
and |
T19838 |
41963-41969 |
VB |
denotes |
loaded |
T19839 |
41970-41972 |
IN |
denotes |
on |
T19840 |
41973-41974 |
DT |
denotes |
a |
T19841 |
41975-41976 |
CD |
denotes |
4 |
T19842 |
41976-41977 |
NN |
denotes |
% |
T19843 |
41978-41980 |
CC |
denotes |
or |
T19844 |
41981-41982 |
CD |
denotes |
6 |
T19845 |
41982-41983 |
NN |
denotes |
% |
T19846 |
41984-41985 |
-LRB- |
denotes |
( |
T19847 |
41985-41988 |
NN |
denotes |
w/v |
T19848 |
41988-41989 |
-RRB- |
denotes |
) |
T19849 |
41990-42004 |
NN |
denotes |
polyacrylamide |
T19850 |
42005-42008 |
NN |
denotes |
gel |
T19851 |
42010-42025 |
NN |
denotes |
Electrophoresis |
T19852 |
42026-42029 |
VB |
denotes |
was |
T19853 |
42030-42039 |
VB |
denotes |
performed |
T19854 |
42040-42042 |
IN |
denotes |
at |
T19855 |
42043-42044 |
DT |
denotes |
a |
T19856 |
42045-42053 |
JJ |
denotes |
constant |
T19857 |
42054-42056 |
CD |
denotes |
19 |
T19858 |
42057-42061 |
NN |
denotes |
mAmp |
T19859 |
42062-42065 |
IN |
denotes |
for |
T19860 |
42066-42069 |
CD |
denotes |
4–8 |
T19861 |
42070-42071 |
NN |
denotes |
h |
T19862 |
42072-42074 |
IN |
denotes |
at |
T19863 |
42075-42079 |
NN |
denotes |
room |
T19864 |
42080-42091 |
NN |
denotes |
temperature |
T19865 |
42091-42092 |
-COMMA- |
denotes |
, |
T19866 |
42093-42096 |
CC |
denotes |
and |
T19867 |
42097-42100 |
DT |
denotes |
the |
T19868 |
42101-42105 |
NN |
denotes |
gels |
T19869 |
42106-42110 |
VB |
denotes |
were |
T19870 |
42111-42116 |
VB |
denotes |
dried |
T19871 |
42117-42122 |
RB |
denotes |
prior |
T19872 |
42123-42125 |
TO |
denotes |
to |
T19873 |
42126-42141 |
NN |
denotes |
autoradiography |
T19874 |
42143-42153 |
NN |
denotes |
Antibodies |
T19875 |
42154-42158 |
VB |
denotes |
used |
T19876 |
42159-42162 |
IN |
denotes |
for |
T19877 |
42163-42173 |
NN |
denotes |
supershift |
T19878 |
42174-42182 |
NN |
denotes |
analyses |
T19879 |
42183-42191 |
VB |
denotes |
included |
T19880 |
42192-42197 |
NN |
denotes |
c-Myc |
T19881 |
42197-42198 |
-COMMA- |
denotes |
, |
T19882 |
42199-42201 |
NN |
denotes |
HA |
T19883 |
42201-42202 |
-COMMA- |
denotes |
, |
T19884 |
42203-42206 |
CC |
denotes |
and |
T19885 |
42207-42211 |
NN |
denotes |
Sox6 |
T19886 |
42212-42222 |
NN |
denotes |
antibodies |
T19887 |
42223-42224 |
-LRB- |
denotes |
( |
T19888 |
42224-42233 |
VB |
denotes |
described |
T19889 |
42234-42236 |
IN |
denotes |
as |
T19890 |
42237-42242 |
JJ |
denotes |
above |
T19891 |
42242-42243 |
-RRB- |
denotes |
) |
T19892 |
42245-42248 |
DT |
denotes |
The |
T19893 |
42249-42252 |
NN |
denotes |
DNA |
T19894 |
42253-42262 |
NN |
denotes |
sequences |
T19895 |
42263-42265 |
IN |
denotes |
of |
T19896 |
42266-42269 |
DT |
denotes |
the |
T19897 |
42270-42286 |
NN |
denotes |
oligonucleotides |
T19898 |
42287-42290 |
VB |
denotes |
are |
T19899 |
42291-42293 |
IN |
denotes |
as |
T19900 |
42294-42301 |
NN |
denotes |
follows |
T19901 |
42302-42303 |
-LRB- |
denotes |
( |
T19902 |
42303-42307 |
RB |
denotes |
only |
T19903 |
42308-42315 |
JJ |
denotes |
forward |
T19904 |
42316-42322 |
NN |
denotes |
oligos |
T19905 |
42323-42326 |
VB |
denotes |
are |
T19906 |
42327-42333 |
VB |
denotes |
listed |
T19907 |
42333-42334 |
-RRB- |
denotes |
) |
T19908 |
42334-42335 |
-COLON- |
denotes |
: |
T19909 |
42336-42339 |
IN |
denotes |
For |
T19910 |
42340-42343 |
DT |
denotes |
the |
T19911 |
42344-42349 |
JJ |
denotes |
36-bp |
T19912 |
42350-42352 |
NN |
denotes |
WT |
T19913 |
42353-42358 |
NN |
denotes |
probe |
T19914 |
42358-42359 |
-COLON- |
denotes |
: |
T19915 |
42360-42400 |
NN |
denotes |
5′AATGCAGAACAAAGGGTCAGAACATTGTCTGCGAAG3′ |
T19916 |
42401-42402 |
-LRB- |
denotes |
( |
T19917 |
42402-42409 |
NN |
denotes |
MHB1556 |
T19918 |
42409-42410 |
-RRB- |
denotes |
) |
T19919 |
42410-42411 |
-COLON- |
denotes |
; |
T19920 |
42412-42415 |
IN |
denotes |
for |
T19921 |
42416-42422 |
JJ |
denotes |
mutant |
T19922 |
42423-42428 |
NN |
denotes |
probe |
T19923 |
42429-42430 |
CD |
denotes |
1 |
T19924 |
42431-42432 |
-LRB- |
denotes |
( |
T19925 |
42432-42434 |
NN |
denotes |
M1 |
T19926 |
42434-42435 |
-RRB- |
denotes |
) |
T19927 |
42435-42436 |
-COLON- |
denotes |
: |
T19928 |
42437-42470 |
NN |
denotes |
5′AACAAAGGGTCAGAACATTGTCTGCGAAG3′ |
T19929 |
42471-42472 |
-LRB- |
denotes |
( |
T19930 |
42472-42479 |
NN |
denotes |
MHB1644 |
T19931 |
42479-42480 |
-RRB- |
denotes |
) |
T19932 |
42480-42481 |
-COLON- |
denotes |
; |
T19933 |
42482-42485 |
IN |
denotes |
for |
T19934 |
42486-42492 |
JJ |
denotes |
mutant |
T19935 |
42493-42498 |
NN |
denotes |
probe |
T19936 |
42499-42500 |
CD |
denotes |
2 |
T19937 |
42501-42502 |
-LRB- |
denotes |
( |
T19938 |
42502-42504 |
NN |
denotes |
M2 |
T19939 |
42504-42505 |
-RRB- |
denotes |
) |
T19940 |
42505-42506 |
-COLON- |
denotes |
: |
T19941 |
42507-42547 |
NN |
denotes |
5′AATGCAGAACAAAGGGTCAGAtgagTGTCTGCGAAG3′ |
T19942 |
42548-42549 |
-LRB- |
denotes |
( |
T19943 |
42549-42556 |
NN |
denotes |
MHB1648 |
T19944 |
42556-42557 |
-RRB- |
denotes |
) |
T19945 |
42557-42558 |
-COLON- |
denotes |
; |
T19946 |
42559-42562 |
IN |
denotes |
for |
T19947 |
42563-42569 |
JJ |
denotes |
mutant |
T19948 |
42570-42575 |
NN |
denotes |
probe |
T19949 |
42576-42577 |
CD |
denotes |
3 |
T19950 |
42578-42579 |
-LRB- |
denotes |
( |
T19951 |
42579-42581 |
NN |
denotes |
M3 |
T19952 |
42581-42582 |
-RRB- |
denotes |
) |
T19953 |
42582-42583 |
-COLON- |
denotes |
: |
T19954 |
42584-42624 |
NN |
denotes |
5′AATGCAGtgccAAGGGTCAGAACATTGTCTGCGAAG3′ |
T19955 |
42625-42626 |
-LRB- |
denotes |
( |
T19956 |
42626-42633 |
NN |
denotes |
MHB1650 |
T19957 |
42633-42634 |
-RRB- |
denotes |
) |
T20382 |
42637-42641 |
NN |
denotes |
ChIP |
T20383 |
42642-42647 |
NN |
denotes |
assay |
T20384 |
42649-42651 |
IN |
denotes |
As |
T20385 |
42652-42661 |
VB |
denotes |
described |
T20386 |
42662-42664 |
IN |
denotes |
by |
T20387 |
42665-42672 |
NNP |
denotes |
Nouzova |
T20388 |
42673-42674 |
-LRB- |
denotes |
[ |
T20389 |
42674-42676 |
CD |
denotes |
53 |
T20390 |
42676-42677 |
-RRB- |
denotes |
] |
T20391 |
42677-42678 |
-COMMA- |
denotes |
, |
T20392 |
42679-42681 |
IN |
denotes |
in |
T20393 |
42682-42687 |
NN |
denotes |
brief |
T20394 |
42687-42688 |
-COLON- |
denotes |
: |
T20395 |
42689-42694 |
NN |
denotes |
Cells |
T20396 |
42695-42699 |
IN |
denotes |
from |
T20397 |
42700-42703 |
NN |
denotes |
MEL |
T20398 |
42704-42709 |
NN |
denotes |
cells |
T20399 |
42710-42711 |
-LRB- |
denotes |
( |
T20400 |
42711-42712 |
CD |
denotes |
4 |
T20401 |
42713-42714 |
NN |
denotes |
× |
T20402 |
42715-42718 |
CD |
denotes |
107 |
T20403 |
42718-42719 |
-RRB- |
denotes |
) |
T20404 |
42720-42722 |
CC |
denotes |
or |
T20405 |
42723-42728 |
JJ |
denotes |
fetal |
T20406 |
42729-42734 |
NN |
denotes |
liver |
T20407 |
42735-42740 |
NN |
denotes |
cells |
T20408 |
42741-42745 |
IN |
denotes |
from |
T20409 |
42746-42751 |
CD |
denotes |
three |
T20410 |
42752-42760 |
JJ |
denotes |
15.5-dpc |
T20411 |
42761-42763 |
JJ |
denotes |
WT |
T20412 |
42764-42768 |
NN |
denotes |
mice |
T20413 |
42769-42773 |
VB |
denotes |
were |
T20414 |
42774-42781 |
VB |
denotes |
treated |
T20415 |
42782-42786 |
IN |
denotes |
with |
T20416 |
42787-42788 |
CD |
denotes |
1 |
T20417 |
42788-42789 |
NN |
denotes |
% |
T20418 |
42790-42802 |
NN |
denotes |
formaldehyde |
T20419 |
42803-42806 |
IN |
denotes |
for |
T20420 |
42807-42809 |
CD |
denotes |
10 |
T20421 |
42810-42813 |
NN |
denotes |
min |
T20422 |
42814-42816 |
IN |
denotes |
at |
T20423 |
42817-42819 |
CD |
denotes |
37 |
T20424 |
42820-42822 |
NN |
denotes |
°C |
T20425 |
42822-42823 |
-COMMA- |
denotes |
, |
T20426 |
42824-42830 |
VB |
denotes |
rinsed |
T20427 |
42831-42833 |
IN |
denotes |
in |
T20428 |
42834-42842 |
JJ |
denotes |
ice-cold |
T20429 |
42843-42845 |
CD |
denotes |
1× |
T20430 |
42846-42851 |
NNP |
denotes |
Hanks |
T20431 |
42851-42852 |
POS |
denotes |
' |
T20432 |
42853-42861 |
JJ |
denotes |
balanced |
T20433 |
42862-42866 |
NN |
denotes |
salt |
T20434 |
42867-42875 |
NN |
denotes |
solution |
T20435 |
42876-42880 |
IN |
denotes |
with |
T20436 |
42881-42884 |
CD |
denotes |
0.1 |
T20437 |
42884-42885 |
NN |
denotes |
% |
T20438 |
42886-42890 |
NN |
denotes |
EDTA |
T20439 |
42891-42901 |
VB |
denotes |
containing |
T20440 |
42902-42910 |
NN |
denotes |
protease |
T20441 |
42911-42921 |
NN |
denotes |
inhibitors |
T20442 |
42921-42922 |
-COMMA- |
denotes |
, |
T20443 |
42923-42932 |
VB |
denotes |
collected |
T20444 |
42933-42935 |
IN |
denotes |
by |
T20445 |
42936-42950 |
NN |
denotes |
centrifugation |
T20446 |
42951-42953 |
IN |
denotes |
at |
T20447 |
42954-42955 |
CD |
denotes |
4 |
T20448 |
42956-42958 |
NN |
denotes |
°C |
T20449 |
42958-42959 |
-COMMA- |
denotes |
, |
T20450 |
42960-42971 |
VB |
denotes |
resuspended |
T20451 |
42972-42974 |
IN |
denotes |
in |
T20452 |
42975-42976 |
DT |
denotes |
a |
T20453 |
42977-42980 |
NN |
denotes |
SDS |
T20454 |
42981-42986 |
NN |
denotes |
lysis |
T20455 |
42987-42993 |
NN |
denotes |
buffer |
T20456 |
42994-43004 |
VB |
denotes |
containing |
T20457 |
43005-43013 |
NN |
denotes |
protease |
T20458 |
43014-43024 |
NN |
denotes |
inhibitors |
T20459 |
43024-43025 |
-COMMA- |
denotes |
, |
T20460 |
43026-43029 |
CC |
denotes |
and |
T20461 |
43030-43039 |
VB |
denotes |
incubated |
T20462 |
43040-43042 |
IN |
denotes |
on |
T20463 |
43043-43046 |
NN |
denotes |
ice |
T20464 |
43047-43050 |
IN |
denotes |
for |
T20465 |
43051-43053 |
CD |
denotes |
10 |
T20466 |
43054-43057 |
NN |
denotes |
min |
T20467 |
43059-43070 |
JJ |
denotes |
DNA-protein |
T20468 |
43071-43080 |
NN |
denotes |
complexes |
T20469 |
43081-43085 |
VB |
denotes |
were |
T20470 |
43086-43095 |
VB |
denotes |
sonicated |
T20471 |
43096-43098 |
TO |
denotes |
to |
T20472 |
43099-43102 |
CD |
denotes |
200 |
T20473 |
43103-43106 |
CC |
denotes |
and |
T20474 |
43107-43110 |
CD |
denotes |
600 |
T20475 |
43111-43113 |
NN |
denotes |
bp |
T20476 |
43115-43124 |
NN |
denotes |
One-tenth |
T20477 |
43125-43127 |
IN |
denotes |
of |
T20478 |
43128-43131 |
DT |
denotes |
the |
T20479 |
43132-43138 |
NN |
denotes |
sample |
T20480 |
43139-43142 |
VB |
denotes |
was |
T20481 |
43143-43146 |
VB |
denotes |
set |
T20482 |
43147-43152 |
RB |
denotes |
aside |
T20483 |
43153-43156 |
IN |
denotes |
for |
T20484 |
43157-43162 |
NN |
denotes |
input |
T20485 |
43163-43170 |
NN |
denotes |
control |
T20486 |
43170-43171 |
-COMMA- |
denotes |
, |
T20487 |
43172-43175 |
CC |
denotes |
and |
T20488 |
43176-43179 |
DT |
denotes |
the |
T20489 |
43180-43189 |
VB |
denotes |
remaining |
T20490 |
43190-43196 |
NN |
denotes |
sample |
T20491 |
43197-43200 |
VB |
denotes |
was |
T20492 |
43201-43211 |
VB |
denotes |
precleared |
T20493 |
43212-43216 |
IN |
denotes |
with |
T20494 |
43217-43224 |
NN |
denotes |
protein |
T20495 |
43225-43236 |
NN |
denotes |
A-Sepharose |
T20496 |
43237-43238 |
-LRB- |
denotes |
( |
T20497 |
43238-43246 |
NNP |
denotes |
Amersham |
T20498 |
43247-43258 |
NNP |
denotes |
Biosciences |
T20499 |
43258-43259 |
-COMMA- |
denotes |
, |
T20500 |
43260-43270 |
NNP |
denotes |
Piscataway |
T20501 |
43270-43271 |
-COMMA- |
denotes |
, |
T20502 |
43272-43275 |
NNP |
denotes |
New |
T20503 |
43276-43282 |
NNP |
denotes |
Jersey |
T20504 |
43282-43283 |
-COMMA- |
denotes |
, |
T20505 |
43284-43290 |
NNP |
denotes |
United |
T20506 |
43291-43297 |
NNP |
denotes |
States |
T20507 |
43297-43298 |
-RRB- |
denotes |
) |
T20508 |
43300-43309 |
VB |
denotes |
Following |
T20509 |
43310-43321 |
NN |
denotes |
preclearing |
T20510 |
43321-43322 |
-COMMA- |
denotes |
, |
T20511 |
43323-43326 |
DT |
denotes |
the |
T20512 |
43327-43334 |
NN |
denotes |
samples |
T20513 |
43335-43339 |
VB |
denotes |
were |
T20514 |
43340-43345 |
VB |
denotes |
split |
T20515 |
43346-43350 |
IN |
denotes |
into |
T20516 |
43351-43357 |
NN |
denotes |
thirds |
T20517 |
43357-43358 |
-COLON- |
denotes |
: |
T20518 |
43359-43362 |
CD |
denotes |
one |
T20519 |
43363-43369 |
NN |
denotes |
sample |
T20520 |
43370-43377 |
VB |
denotes |
treated |
T20521 |
43378-43382 |
IN |
denotes |
with |
T20522 |
43383-43392 |
NN |
denotes |
anti-Sox6 |
T20523 |
43392-43393 |
-COMMA- |
denotes |
, |
T20524 |
43394-43395 |
DT |
denotes |
a |
T20525 |
43396-43402 |
JJ |
denotes |
second |
T20526 |
43403-43410 |
VB |
denotes |
treated |
T20527 |
43411-43415 |
IN |
denotes |
with |
T20528 |
43416-43422 |
JJ |
denotes |
normal |
T20529 |
43423-43429 |
NN |
denotes |
rabbit |
T20530 |
43430-43433 |
NN |
denotes |
IgG |
T20531 |
43433-43434 |
-COMMA- |
denotes |
, |
T20532 |
43435-43438 |
CC |
denotes |
and |
T20533 |
43439-43442 |
DT |
denotes |
the |
T20534 |
43443-43448 |
JJ |
denotes |
third |
T20535 |
43449-43455 |
NN |
denotes |
sample |
T20536 |
43456-43463 |
IN |
denotes |
without |
T20537 |
43464-43467 |
NNP |
denotes |
Ab. |
T20538 |
43468-43471 |
DT |
denotes |
The |
T20539 |
43472-43476 |
JJ |
denotes |
last |
T20540 |
43477-43480 |
CD |
denotes |
two |
T20541 |
43481-43485 |
VB |
denotes |
were |
T20542 |
43486-43490 |
VB |
denotes |
used |
T20543 |
43491-43493 |
IN |
denotes |
as |
T20544 |
43494-43502 |
JJ |
denotes |
negative |
T20545 |
43503-43511 |
NN |
denotes |
controls |
T20546 |
43513-43516 |
DT |
denotes |
The |
T20547 |
43517-43535 |
NN |
denotes |
chromatin-antibody |
T20548 |
43536-43545 |
NN |
denotes |
complexes |
T20549 |
43546-43550 |
VB |
denotes |
were |
T20550 |
43551-43557 |
VB |
denotes |
eluted |
T20551 |
43557-43558 |
-COMMA- |
denotes |
, |
T20552 |
43559-43562 |
CC |
denotes |
and |
T20553 |
43563-43566 |
DT |
denotes |
the |
T20554 |
43567-43570 |
NN |
denotes |
DNA |
T20555 |
43571-43578 |
NN |
denotes |
protein |
T20556 |
43579-43590 |
NN |
denotes |
cross-links |
T20557 |
43591-43595 |
VB |
denotes |
were |
T20558 |
43596-43604 |
VB |
denotes |
reversed |
T20559 |
43605-43609 |
IN |
denotes |
with |
T20560 |
43610-43611 |
CD |
denotes |
5 |
T20561 |
43612-43613 |
NN |
denotes |
M |
T20562 |
43614-43618 |
NN |
denotes |
NaCl |
T20563 |
43619-43621 |
IN |
denotes |
at |
T20564 |
43622-43624 |
CD |
denotes |
65 |
T20565 |
43625-43627 |
NN |
denotes |
°C |
T20566 |
43628-43631 |
IN |
denotes |
for |
T20567 |
43632-43633 |
CD |
denotes |
4 |
T20568 |
43634-43635 |
NN |
denotes |
h |
T20569 |
43637-43642 |
NN |
denotes |
Input |
T20570 |
43643-43646 |
NN |
denotes |
DNA |
T20571 |
43647-43649 |
CC |
denotes |
or |
T20572 |
43650-43668 |
VB |
denotes |
immunoprecipitated |
T20573 |
43669-43672 |
NN |
denotes |
DNA |
T20574 |
43673-43676 |
VB |
denotes |
was |
T20575 |
43677-43681 |
VB |
denotes |
used |
T20576 |
43682-43684 |
IN |
denotes |
as |
T20577 |
43685-43686 |
DT |
denotes |
a |
T20578 |
43687-43695 |
NN |
denotes |
template |
T20579 |
43696-43698 |
IN |
denotes |
in |
T20580 |
43699-43702 |
DT |
denotes |
the |
T20581 |
43703-43706 |
NN |
denotes |
PCR |
T20582 |
43707-43715 |
NN |
denotes |
reaction |
T20583 |
43717-43720 |
NN |
denotes |
PCR |
T20584 |
43721-43734 |
NN |
denotes |
amplification |
T20585 |
43735-43737 |
IN |
denotes |
of |
T20586 |
43738-43741 |
DT |
denotes |
the |
T20587 |
43742-43744 |
JJ |
denotes |
ɛy |
T20588 |
43745-43753 |
NN |
denotes |
promoter |
T20589 |
43754-43757 |
VB |
denotes |
was |
T20590 |
43758-43767 |
VB |
denotes |
performed |
T20591 |
43768-43771 |
CC |
denotes |
and |
T20592 |
43772-43779 |
VB |
denotes |
yielded |
T20593 |
43780-43781 |
DT |
denotes |
a |
T20594 |
43782-43788 |
JJ |
denotes |
172-bp |
T20595 |
43789-43797 |
NN |
denotes |
amplicon |
T20596 |
43797-43798 |
-COMMA- |
denotes |
, |
T20597 |
43799-43812 |
VB |
denotes |
corresponding |
T20598 |
43813-43815 |
TO |
denotes |
to |
T20599 |
43816-43827 |
NN |
denotes |
nucleotides |
T20600 |
43828-43831 |
CD |
denotes |
−31 |
T20601 |
43832-43834 |
TO |
denotes |
to |
T20602 |
43835-43839 |
CD |
denotes |
+140 |
T20603 |
43840-43842 |
IN |
denotes |
of |
T20604 |
43843-43846 |
DT |
denotes |
the |
T20605 |
43847-43849 |
JJ |
denotes |
ɛy |
T20606 |
43850-43858 |
NN |
denotes |
promoter |
T20607 |
43859-43860 |
-LRB- |
denotes |
( |
T20608 |
43860-43867 |
NN |
denotes |
primers |
T20609 |
43868-43875 |
NN |
denotes |
MHB1688 |
T20610 |
43875-43876 |
-COMMA- |
denotes |
, |
T20611 |
43877-43901 |
NN |
denotes |
5′CGAAGAATAAAAGGCCACCA3′ |
T20612 |
43901-43902 |
-COLON- |
denotes |
; |
T20613 |
43903-43906 |
CC |
denotes |
and |
T20614 |
43907-43914 |
NN |
denotes |
MHB1689 |
T20615 |
43914-43915 |
-COMMA- |
denotes |
, |
T20616 |
43916-43940 |
NN |
denotes |
5′GCTTCACCACCAACCTCTTC3′ |
T20617 |
43940-43941 |
-RRB- |
denotes |
) |
T20618 |
43943-43946 |
NN |
denotes |
PCR |
T20619 |
43947-43950 |
VB |
denotes |
was |
T20620 |
43951-43960 |
VB |
denotes |
performed |
T20621 |
43961-43966 |
IN |
denotes |
under |
T20622 |
43967-43970 |
DT |
denotes |
the |
T20623 |
43971-43980 |
JJ |
denotes |
following |
T20624 |
43981-43991 |
NN |
denotes |
conditions |
T20625 |
43991-43992 |
-COLON- |
denotes |
: |
T20626 |
43993-43995 |
CD |
denotes |
95 |
T20627 |
43996-43998 |
NN |
denotes |
°C |
T20628 |
43999-44002 |
IN |
denotes |
for |
T20629 |
44003-44005 |
CD |
denotes |
15 |
T20630 |
44006-44009 |
NN |
denotes |
min |
T20631 |
44010-44018 |
VB |
denotes |
followed |
T20632 |
44019-44021 |
IN |
denotes |
by |
T20633 |
44022-44024 |
CD |
denotes |
30 |
T20634 |
44025-44031 |
NN |
denotes |
cycles |
T20635 |
44032-44034 |
IN |
denotes |
at |
T20636 |
44035-44037 |
CD |
denotes |
95 |
T20637 |
44038-44040 |
NN |
denotes |
°C |
T20638 |
44041-44044 |
IN |
denotes |
for |
T20639 |
44045-44047 |
CD |
denotes |
30 |
T20640 |
44048-44049 |
NN |
denotes |
s |
T20641 |
44049-44050 |
-COMMA- |
denotes |
, |
T20642 |
44051-44053 |
CD |
denotes |
60 |
T20643 |
44054-44056 |
NN |
denotes |
°C |
T20644 |
44057-44060 |
IN |
denotes |
for |
T20645 |
44061-44063 |
CD |
denotes |
30 |
T20646 |
44064-44065 |
NN |
denotes |
s |
T20647 |
44065-44066 |
-COMMA- |
denotes |
, |
T20648 |
44067-44070 |
CC |
denotes |
and |
T20649 |
44071-44073 |
CD |
denotes |
72 |
T20650 |
44074-44076 |
NN |
denotes |
°C |
T20651 |
44077-44080 |
IN |
denotes |
for |
T20652 |
44081-44083 |
CD |
denotes |
45 |
T20653 |
44084-44085 |
NN |
denotes |
s |
T20654 |
44085-44086 |
-COMMA- |
denotes |
, |
T20655 |
44087-44093 |
VB |
denotes |
ending |
T20656 |
44094-44098 |
IN |
denotes |
with |
T20657 |
44099-44100 |
DT |
denotes |
a |
T20658 |
44101-44106 |
JJ |
denotes |
final |
T20659 |
44107-44116 |
NN |
denotes |
extension |
T20660 |
44117-44119 |
IN |
denotes |
at |
T20661 |
44120-44122 |
CD |
denotes |
72 |
T20662 |
44123-44125 |
NN |
denotes |
°C |
T20663 |
44126-44129 |
IN |
denotes |
for |
T20664 |
44130-44131 |
CD |
denotes |
5 |
T20665 |
44132-44135 |
NN |
denotes |
min |
R100 |
T310 |
T308 |
arg1Of |
system,central |
R1000 |
T1885 |
T1888 |
arg1Of |
",",or |
R1001 |
T1886 |
T1885 |
arg2Of |
Sox9,"," |
R1002 |
T1888 |
T1882 |
arg2Of |
or,of |
R1003 |
T1888 |
T1883 |
arg1Of |
or,either |
R1004 |
T1888 |
T1887 |
arg1Of |
or,"," |
R1005 |
T1889 |
T1888 |
arg2Of |
Sry,or |
R1006 |
T1892 |
T1890 |
arg2Of |
extracts,in |
R1007 |
T1892 |
T1891 |
arg1Of |
extracts,the |
R1008 |
T1893 |
T1876 |
arg2Of |
restored,and |
R1009 |
T1893 |
T1895 |
arg1Of |
restored,"," |
R101 |
T310 |
T309 |
arg1Of |
system,nervous |
R1010 |
T1894 |
T1893 |
arg2Of |
splicing,restored |
R1011 |
T1898 |
T1896 |
arg2Of |
overlap,indicating |
R1012 |
T1898 |
T1897 |
arg1Of |
overlap,functional |
R1013 |
T1898 |
T1899 |
arg1Of |
overlap,of |
R1014 |
T1901 |
T1899 |
arg2Of |
proteins,of |
R1015 |
T1901 |
T1900 |
arg1Of |
proteins,these |
R1016 |
T1903 |
T1902 |
arg2Of |
7,[ |
R1017 |
T1904 |
T1902 |
arg3Of |
],[ |
R1018 |
T1905 |
T1906 |
arg1Of |
Regardless,of |
R1019 |
T1907 |
T1906 |
arg2Of |
how,of |
R102 |
T311 |
T314 |
arg1Of |
",",and |
R1020 |
T1909 |
T1908 |
arg1Of |
functions,Sox6 |
R1021 |
T1909 |
T1910 |
arg1Of |
functions,in |
R1022 |
T1909 |
T1911 |
arg1Of |
functions,regulating |
R1023 |
T1911 |
T1907 |
arg1Of |
regulating,how |
R1024 |
T1913 |
T1911 |
arg2Of |
expression,regulating |
R1025 |
T1913 |
T1912 |
arg1Of |
expression,gene |
R1026 |
T1916 |
T1915 |
arg1Of |
studies,previous |
R1027 |
T1916 |
T1917 |
arg1Of |
studies,have |
R1028 |
T1916 |
T1918 |
arg1Of |
studies,demonstrated |
R1029 |
T1918 |
T1905 |
arg1Of |
demonstrated,Regardless |
R103 |
T312 |
T311 |
arg2Of |
cartilage,"," |
R1030 |
T1918 |
T1914 |
arg1Of |
demonstrated,"," |
R1031 |
T1918 |
T1917 |
arg2Of |
demonstrated,have |
R1032 |
T1920 |
T1921 |
arg1Of |
Sox6,is |
R1033 |
T1921 |
T1918 |
arg2Of |
is,demonstrated |
R1034 |
T1921 |
T1919 |
arg1Of |
is,that |
R1035 |
T1925 |
T1921 |
arg2Of |
molecule,is |
R1036 |
T1925 |
T1922 |
arg1Of |
molecule,an |
R1037 |
T1925 |
T1923 |
arg1Of |
molecule,important |
R1038 |
T1925 |
T1924 |
arg1Of |
molecule,regulatory |
R1039 |
T1925 |
T1926 |
arg1Of |
molecule,that |
R104 |
T314 |
T303 |
arg2Of |
and,in |
R1040 |
T1925 |
T1927 |
arg1Of |
molecule,plays |
R1041 |
T1927 |
T1930 |
arg1Of |
plays,in |
R1042 |
T1929 |
T1927 |
arg2Of |
role,plays |
R1043 |
T1929 |
T1928 |
arg1Of |
role,a |
R1044 |
T1932 |
T1933 |
arg1Of |
development,of |
R1045 |
T1932 |
T1941 |
arg1Of |
development,"," |
R1046 |
T1937 |
T1933 |
arg2Of |
system,of |
R1047 |
T1937 |
T1934 |
arg1Of |
system,the |
R1048 |
T1937 |
T1935 |
arg1Of |
system,central |
R1049 |
T1937 |
T1936 |
arg1Of |
system,nervous |
R105 |
T314 |
T304 |
arg1Of |
and,the |
R1050 |
T1937 |
T1938 |
arg1Of |
system,[ |
R1051 |
T1939 |
T1938 |
arg2Of |
8–11,[ |
R1052 |
T1940 |
T1938 |
arg3Of |
],[ |
R1053 |
T1941 |
T1947 |
arg1Of |
",",and |
R1054 |
T1942 |
T1941 |
arg2Of |
cartilage,"," |
R1055 |
T1942 |
T1943 |
arg1Of |
cartilage,[ |
R1056 |
T1944 |
T1943 |
arg2Of |
"6,12,13",[ |
R1057 |
T1945 |
T1943 |
arg3Of |
],[ |
R1058 |
T1947 |
T1930 |
arg2Of |
and,in |
R1059 |
T1947 |
T1931 |
arg1Of |
and,the |
R106 |
T314 |
T313 |
arg1Of |
and,"," |
R1060 |
T1947 |
T1946 |
arg1Of |
and,"," |
R1061 |
T1948 |
T1947 |
arg2Of |
muscle,and |
R1062 |
T1948 |
T1949 |
arg1Of |
muscle,[ |
R1063 |
T1950 |
T1949 |
arg2Of |
"14,15",[ |
R1064 |
T1951 |
T1949 |
arg3Of |
],[ |
R1065 |
T1955 |
T1952 |
arg1Of |
mouse,A |
R1066 |
T1955 |
T1953 |
arg1Of |
mouse,Sox6-null |
R1067 |
T1955 |
T1954 |
arg1Of |
mouse,mutant |
R1068 |
T1955 |
T1956 |
arg1Of |
mouse,( |
R1069 |
T1955 |
T1959 |
arg1Of |
mouse,has |
R107 |
T315 |
T314 |
arg2Of |
muscle,and |
R1070 |
T1955 |
T1961 |
arg1Of |
mouse,been |
R1071 |
T1955 |
T1962 |
arg2Of |
mouse,identified |
R1072 |
T1957 |
T1956 |
arg2Of |
p100H,( |
R1073 |
T1958 |
T1956 |
arg3Of |
),( |
R1074 |
T1962 |
T1959 |
arg2Of |
identified,has |
R1075 |
T1962 |
T1960 |
arg1Of |
identified,previously |
R1076 |
T1962 |
T1961 |
arg2Of |
identified,been |
R1077 |
T1962 |
T1963 |
arg1Of |
identified,in |
R1078 |
T1965 |
T1963 |
arg2Of |
laboratory,in |
R1079 |
T1965 |
T1964 |
arg1Of |
laboratory,our |
R108 |
T319 |
T316 |
arg2Of |
mouse,In |
R1080 |
T1965 |
T1966 |
arg1Of |
laboratory,[ |
R1081 |
T1967 |
T1966 |
arg2Of |
14,[ |
R1082 |
T1968 |
T1966 |
arg3Of |
],[ |
R1083 |
T1969 |
T1970 |
arg1Of |
Mice,homozygous |
R1084 |
T1969 |
T1973 |
arg1Of |
Mice,show |
R1085 |
T1969 |
T1977 |
arg1Of |
Mice,develop |
R1086 |
T1969 |
T1985 |
arg1Of |
Mice,die |
R1087 |
T1970 |
T1971 |
arg1Of |
homozygous,for |
R1088 |
T1972 |
T1971 |
arg2Of |
p100H,for |
R1089 |
T1973 |
T1976 |
arg1Of |
show,"," |
R109 |
T319 |
T317 |
arg1Of |
mouse,the |
R1090 |
T1975 |
T1973 |
arg2Of |
growth,show |
R1091 |
T1975 |
T1974 |
arg2Of |
growth,delayed |
R1092 |
T1976 |
T1984 |
arg1Of |
",",and |
R1093 |
T1977 |
T1976 |
arg2Of |
develop,"," |
R1094 |
T1978 |
T1979 |
arg1Of |
myopathy,and |
R1095 |
T1980 |
T1979 |
arg2Of |
arterioventricular,and |
R1096 |
T1982 |
T1977 |
arg2Of |
block,develop |
R1097 |
T1982 |
T1978 |
arg1Of |
block,myopathy |
R1098 |
T1982 |
T1980 |
arg1Of |
block,arterioventricular |
R1099 |
T1982 |
T1981 |
arg1Of |
block,heart |
R110 |
T319 |
T318 |
arg1Of |
mouse,Sox6-deficient |
R1100 |
T1984 |
T1983 |
arg1Of |
and,"," |
R1101 |
T1984 |
T1991 |
arg1Of |
and,[ |
R1102 |
T1985 |
T1984 |
arg2Of |
die,and |
R1103 |
T1985 |
T1986 |
arg1Of |
die,within |
R1104 |
T1985 |
T1989 |
arg1Of |
die,after |
R1105 |
T1988 |
T1986 |
arg2Of |
wk,within |
R1106 |
T1988 |
T1987 |
arg1Of |
wk,2 |
R1107 |
T1990 |
T1989 |
arg2Of |
birth,after |
R1108 |
T1992 |
T1991 |
arg2Of |
14,[ |
R11081 |
T16074 |
T16073 |
arg1Of |
construction,Plasmid |
R11082 |
T16080 |
T16075 |
arg1Of |
plasmid,The |
R11083 |
T16080 |
T16076 |
arg1Of |
plasmid,ɛy |
R11084 |
T16080 |
T16077 |
arg1Of |
plasmid,promoter |
R11085 |
T16080 |
T16078 |
arg1Of |
plasmid,deletion |
R11086 |
T16080 |
T16079 |
arg1Of |
plasmid,reporter |
R11087 |
T16080 |
T16081 |
arg1Of |
plasmid,( |
R11088 |
T16080 |
T16084 |
arg1Of |
plasmid,was |
R11089 |
T16080 |
T16085 |
arg2Of |
plasmid,generated |
R1109 |
T1993 |
T1991 |
arg3Of |
],[ |
R11090 |
T16082 |
T16081 |
arg2Of |
E-luc,( |
R11091 |
T16083 |
T16081 |
arg3Of |
),( |
R11092 |
T16085 |
T16084 |
arg2Of |
generated,was |
R11093 |
T16088 |
T16085 |
arg1Of |
amplification,generated |
R11094 |
T16088 |
T16086 |
arg2Of |
amplification,by |
R11095 |
T16088 |
T16087 |
arg1Of |
amplification,PCR |
R11096 |
T16088 |
T16089 |
arg1Of |
amplification,of |
R11097 |
T16093 |
T16089 |
arg2Of |
promoter,of |
R11098 |
T16093 |
T16090 |
arg1Of |
promoter,the |
R11099 |
T16093 |
T16091 |
arg1Of |
promoter,ɛy |
R111 |
T319 |
T320 |
arg1Of |
mouse,"," |
R1110 |
T1997 |
T1994 |
arg1Of |
allele,The |
R11100 |
T16093 |
T16092 |
arg1Of |
promoter,proximal |
R11101 |
T16096 |
T16094 |
arg1Of |
fragment,A |
R11102 |
T16096 |
T16095 |
arg1Of |
fragment,2.2-kb |
R11103 |
T16096 |
T16097 |
arg1Of |
fragment,upstream |
R11104 |
T16096 |
T16107 |
arg1Of |
fragment,was |
R11105 |
T16096 |
T16108 |
arg2Of |
fragment,used |
R11106 |
T16097 |
T16098 |
arg1Of |
upstream,of |
R11107 |
T16103 |
T16098 |
arg2Of |
codon,of |
R11108 |
T16103 |
T16099 |
arg1Of |
codon,the |
R11109 |
T16103 |
T16100 |
arg1Of |
codon,ɛy |
R1111 |
T1997 |
T1995 |
arg1Of |
allele,p100H |
R11110 |
T16103 |
T16101 |
arg1Of |
codon,globin |
R11111 |
T16103 |
T16102 |
arg1Of |
codon,initiation |
R11112 |
T16103 |
T16104 |
arg1Of |
codon,( |
R11113 |
T16105 |
T16104 |
arg2Of |
ATG,( |
R11114 |
T16106 |
T16104 |
arg3Of |
),( |
R11115 |
T16108 |
T16107 |
arg2Of |
used,was |
R11116 |
T16108 |
T16109 |
arg1Of |
used,"," |
R11117 |
T16108 |
T16110 |
arg1Of |
used,because |
R11118 |
T16111 |
T16112 |
arg1Of |
it,has |
R11119 |
T16111 |
T16113 |
arg1Of |
it,been |
R1112 |
T1997 |
T1996 |
arg1Of |
allele,mutant |
R11120 |
T16111 |
T16114 |
arg2Of |
it,shown |
R11121 |
T16114 |
T16110 |
arg2Of |
shown,because |
R11122 |
T16114 |
T16112 |
arg2Of |
shown,has |
R11123 |
T16114 |
T16113 |
arg2Of |
shown,been |
R11124 |
T16117 |
T16116 |
arg1Of |
sequences,all |
R11125 |
T16117 |
T16118 |
arg2Of |
sequences,required |
R11126 |
T16117 |
T16123 |
arg1Of |
sequences,are |
R11127 |
T16117 |
T16124 |
arg1Of |
sequences,located |
R11128 |
T16118 |
T16119 |
arg1Of |
required,for |
R11129 |
T16122 |
T16119 |
arg2Of |
silencing,for |
R1113 |
T1997 |
T1998 |
arg1Of |
allele,is |
R11130 |
T16122 |
T16120 |
arg1Of |
silencing,ɛ |
R11131 |
T16122 |
T16121 |
arg1Of |
silencing,gene |
R11132 |
T16123 |
T16114 |
arg3Of |
are,shown |
R11133 |
T16123 |
T16115 |
arg1Of |
are,that |
R11134 |
T16124 |
T16123 |
arg2Of |
located,are |
R11135 |
T16124 |
T16125 |
arg1Of |
located,within |
R11136 |
T16129 |
T16125 |
arg2Of |
fragment,within |
R11137 |
T16129 |
T16126 |
arg1Of |
fragment,a |
R11138 |
T16129 |
T16127 |
arg1Of |
fragment,3.7-kb |
R11139 |
T16129 |
T16128 |
arg1Of |
fragment,EcoRI |
R1114 |
T1997 |
T1999 |
arg2Of |
allele,associated |
R11140 |
T16129 |
T16130 |
arg1Of |
fragment,containing |
R11141 |
T16130 |
T16144 |
arg1Of |
containing,[ |
R11142 |
T16132 |
T16131 |
arg1Of |
2,about |
R11143 |
T16133 |
T16130 |
arg2Of |
kb,containing |
R11144 |
T16133 |
T16132 |
arg1Of |
kb,2 |
R11145 |
T16133 |
T16134 |
arg1Of |
kb,of |
R11146 |
T16133 |
T16136 |
arg1Of |
kb,upstream |
R11147 |
T16135 |
T16134 |
arg2Of |
sequence,of |
R11148 |
T16136 |
T16137 |
arg1Of |
upstream,of |
R11149 |
T16143 |
T16137 |
arg2Of |
site,of |
R1115 |
T1999 |
T1998 |
arg2Of |
associated,is |
R11150 |
T16143 |
T16138 |
arg1Of |
site,the |
R11151 |
T16143 |
T16139 |
arg1Of |
site,ɛ |
R11152 |
T16143 |
T16140 |
arg1Of |
site,globin |
R11153 |
T16143 |
T16141 |
arg1Of |
site,gene |
R11154 |
T16143 |
T16142 |
arg1Of |
site,cap |
R11155 |
T16145 |
T16144 |
arg2Of |
50,[ |
R11156 |
T16146 |
T16144 |
arg3Of |
],[ |
R11157 |
T16148 |
T16147 |
arg1Of |
numbering,Nucleotide |
R11158 |
T16148 |
T16149 |
arg1Of |
numbering,is |
R11159 |
T16148 |
T16150 |
arg1Of |
numbering,relative |
R1116 |
T1999 |
T2000 |
arg1Of |
associated,with |
R11160 |
T16150 |
T16149 |
arg2Of |
relative,is |
R11161 |
T16150 |
T16151 |
arg1Of |
relative,to |
R11162 |
T16155 |
T16151 |
arg2Of |
site,to |
R11163 |
T16155 |
T16152 |
arg1Of |
site,the |
R11164 |
T16155 |
T16153 |
arg1Of |
site,transcription |
R11165 |
T16155 |
T16154 |
arg1Of |
site,start |
R11166 |
T16159 |
T16156 |
arg1Of |
site,The |
R11167 |
T16159 |
T16157 |
arg1Of |
site,transcriptional |
R11168 |
T16159 |
T16158 |
arg1Of |
site,start |
R11169 |
T16159 |
T16160 |
arg1Of |
site,is |
R1117 |
T2004 |
T2000 |
arg2Of |
inversion,with |
R11170 |
T16159 |
T16161 |
arg2Of |
site,based |
R11171 |
T16161 |
T16160 |
arg2Of |
based,is |
R11172 |
T16161 |
T16162 |
arg1Of |
based,on |
R11173 |
T16165 |
T16162 |
arg2Of |
cDNA,on |
R11174 |
T16165 |
T16163 |
arg1Of |
cDNA,the |
R11175 |
T16165 |
T16164 |
arg1Of |
cDNA,longest |
R11176 |
T16165 |
T16166 |
arg1Of |
cDNA,in |
R11177 |
T16168 |
T16169 |
arg1Of |
Fantom,( |
R11178 |
T16171 |
T16169 |
arg2Of |
Annotation,( |
R11179 |
T16171 |
T16170 |
arg1Of |
Annotation,Functional |
R1118 |
T2004 |
T2001 |
arg1Of |
inversion,a |
R11180 |
T16171 |
T16172 |
arg1Of |
Annotation,of |
R11181 |
T16173 |
T16172 |
arg2Of |
Mouse,of |
R11182 |
T16174 |
T16169 |
arg3Of |
),( |
R11183 |
T16175 |
T16166 |
arg2Of |
database,in |
R11184 |
T16175 |
T16167 |
arg1Of |
database,the |
R11185 |
T16175 |
T16168 |
arg1Of |
database,Fantom |
R11186 |
T16178 |
T16176 |
arg1Of |
primers,The |
R11187 |
T16178 |
T16177 |
arg1Of |
primers,PCR |
R11188 |
T16178 |
T16179 |
arg1Of |
primers,contained |
R11189 |
T16180 |
T16181 |
arg1Of |
XhoI,and |
R1119 |
T2004 |
T2002 |
arg1Of |
inversion,Chromosome |
R11190 |
T16182 |
T16181 |
arg2Of |
HindIII,and |
R11191 |
T16183 |
T16179 |
arg2Of |
sites,contained |
R11192 |
T16183 |
T16180 |
arg1Of |
sites,XhoI |
R11193 |
T16183 |
T16182 |
arg1Of |
sites,HindIII |
R11194 |
T16183 |
T16184 |
arg1Of |
sites,that |
R11195 |
T16183 |
T16185 |
arg1Of |
sites,were |
R11196 |
T16183 |
T16186 |
arg2Of |
sites,used |
R11197 |
T16186 |
T16185 |
arg2Of |
used,were |
R11198 |
T16188 |
T16186 |
arg3Of |
clone,used |
R11199 |
T16188 |
T16187 |
arg1Of |
clone,to |
R112 |
T321 |
T320 |
arg2Of |
p100H,"," |
R1120 |
T2004 |
T2003 |
arg1Of |
inversion,7 |
R11200 |
T16188 |
T16193 |
arg1Of |
clone,upstream |
R11201 |
T16192 |
T16188 |
arg2Of |
fragment,clone |
R11202 |
T16192 |
T16189 |
arg1Of |
fragment,the |
R11203 |
T16192 |
T16190 |
arg1Of |
fragment,ɛy |
R11204 |
T16192 |
T16191 |
arg1Of |
fragment,promoter |
R11205 |
T16193 |
T16194 |
arg1Of |
upstream,of |
R11206 |
T16198 |
T16194 |
arg2Of |
gene,of |
R11207 |
T16198 |
T16195 |
arg1Of |
gene,the |
R11208 |
T16198 |
T16196 |
arg1Of |
gene,firefly |
R11209 |
T16198 |
T16197 |
arg1Of |
gene,luciferase |
R1121 |
T2004 |
T2005 |
arg1Of |
inversion,that |
R11210 |
T16198 |
T16199 |
arg1Of |
gene,in |
R11211 |
T16201 |
T16200 |
arg1Of |
Basic,pGL3 |
R11212 |
T16203 |
T16204 |
arg1Of |
Promega,"," |
R11213 |
T16204 |
T16206 |
arg1Of |
",","," |
R11214 |
T16205 |
T16204 |
arg2Of |
Madison,"," |
R11215 |
T16206 |
T16208 |
arg1Of |
",","," |
R11216 |
T16207 |
T16206 |
arg2Of |
Wisconsin,"," |
R11217 |
T16208 |
T16199 |
arg2Of |
",",in |
R11218 |
T16208 |
T16201 |
arg1Of |
",",Basic |
R11219 |
T16208 |
T16202 |
arg2Of |
",",( |
R1122 |
T2004 |
T2006 |
arg1Of |
inversion,disrupts |
R11220 |
T16210 |
T16208 |
arg2Of |
States,"," |
R11221 |
T16210 |
T16209 |
arg1Of |
States,United |
R11222 |
T16211 |
T16202 |
arg3Of |
),( |
R11223 |
T16215 |
T16212 |
arg1Of |
fragment,A |
R11224 |
T16215 |
T16213 |
arg1Of |
fragment,2.5-kb |
R11225 |
T16215 |
T16214 |
arg1Of |
fragment,SstI/XhoI |
R11226 |
T16215 |
T16216 |
arg1Of |
fragment,of |
R11227 |
T16215 |
T16219 |
arg1Of |
fragment,( |
R11228 |
T16215 |
T16227 |
arg1Of |
fragment,was |
R11229 |
T16215 |
T16229 |
arg2Of |
fragment,inserted |
R1123 |
T2006 |
T2028 |
arg1Of |
disrupts,[ |
R11230 |
T16217 |
T16216 |
arg2Of |
μLCRβ,of |
R11231 |
T16217 |
T16218 |
arg1Of |
μLCRβ,9.3 |
R11232 |
T16221 |
T16220 |
arg1Of |
LCR,micro |
R11233 |
T16221 |
T16222 |
arg1Of |
LCR,; |
R11234 |
T16222 |
T16219 |
arg2Of |
;,( |
R11235 |
T16224 |
T16222 |
arg2Of |
31,; |
R11236 |
T16224 |
T16223 |
arg2Of |
31,[ |
R11237 |
T16225 |
T16223 |
arg3Of |
],[ |
R11238 |
T16226 |
T16219 |
arg3Of |
),( |
R11239 |
T16229 |
T16227 |
arg2Of |
inserted,was |
R1124 |
T2010 |
T2008 |
arg1Of |
gene,the |
R11240 |
T16229 |
T16228 |
arg1Of |
inserted,then |
R11241 |
T16229 |
T16230 |
arg1Of |
inserted,upstream |
R11242 |
T16229 |
T16235 |
arg1Of |
inserted,in |
R11243 |
T16229 |
T16241 |
arg1Of |
inserted,"," |
R11244 |
T16229 |
T16242 |
modOf |
inserted,resulting |
R11245 |
T16230 |
T16231 |
arg1Of |
upstream,of |
R11246 |
T16234 |
T16231 |
arg2Of |
promoter,of |
R11247 |
T16234 |
T16232 |
arg1Of |
promoter,the |
R11248 |
T16234 |
T16233 |
arg1Of |
promoter,ɛy |
R11249 |
T16239 |
T16238 |
arg1Of |
Basic,pGL3 |
R1125 |
T2010 |
T2009 |
arg1Of |
gene,p |
R11250 |
T16240 |
T16235 |
arg2Of |
plasmid,in |
R11251 |
T16240 |
T16236 |
arg1Of |
plasmid,the |
R11252 |
T16240 |
T16237 |
arg1Of |
plasmid,above |
R11253 |
T16240 |
T16239 |
arg1Of |
plasmid,Basic |
R11254 |
T16242 |
T16243 |
arg1Of |
resulting,in |
R11255 |
T16246 |
T16243 |
arg2Of |
construct,in |
R11256 |
T16246 |
T16244 |
arg1Of |
construct,a |
R11257 |
T16246 |
T16245 |
arg1Of |
construct,reporter |
R11258 |
T16246 |
T16247 |
arg2Of |
construct,in |
R11259 |
T16246 |
T16248 |
arg1Of |
construct,which |
R1126 |
T2010 |
T2011 |
arg1Of |
gene,and |
R11260 |
T16250 |
T16249 |
arg1Of |
expression,luciferase |
R11261 |
T16250 |
T16251 |
arg1Of |
expression,is |
R11262 |
T16250 |
T16252 |
arg2Of |
expression,driven |
R11263 |
T16252 |
T16247 |
arg1Of |
driven,in |
R11264 |
T16252 |
T16251 |
arg2Of |
driven,is |
R11265 |
T16256 |
T16252 |
arg1Of |
promoter,driven |
R11266 |
T16256 |
T16253 |
arg2Of |
promoter,by |
R11267 |
T16256 |
T16254 |
arg1Of |
promoter,the |
R11268 |
T16256 |
T16255 |
arg1Of |
promoter,ɛy |
R11269 |
T16258 |
T16257 |
arg1Of |
series,A |
R1127 |
T2011 |
T2006 |
arg2Of |
and,disrupts |
R11270 |
T16258 |
T16259 |
arg1Of |
series,of |
R11271 |
T16258 |
T16266 |
arg1Of |
series,were |
R11272 |
T16258 |
T16267 |
arg2Of |
series,generated |
R11273 |
T16261 |
T16259 |
arg2Of |
constructs,of |
R11274 |
T16261 |
T16260 |
arg1Of |
constructs,deletion |
R11275 |
T16261 |
T16262 |
arg1Of |
constructs,of |
R11276 |
T16265 |
T16262 |
arg2Of |
promoter,of |
R11277 |
T16265 |
T16263 |
arg1Of |
promoter,the |
R11278 |
T16265 |
T16264 |
arg1Of |
promoter,ɛy |
R11279 |
T16267 |
T16266 |
arg2Of |
generated,were |
R1128 |
T2011 |
T2007 |
arg1Of |
and,both |
R11280 |
T16267 |
T16268 |
arg1Of |
generated,similarly |
R11281 |
T16270 |
T16269 |
arg1Of |
primers,Forward |
R11282 |
T16270 |
T16271 |
arg1Of |
primers,with |
R11283 |
T16270 |
T16275 |
arg1Of |
primers,include |
R11284 |
T16274 |
T16271 |
arg2Of |
site,with |
R11285 |
T16274 |
T16272 |
arg1Of |
site,an |
R11286 |
T16274 |
T16273 |
arg1Of |
site,XhoI |
R11287 |
T16275 |
T16276 |
arg1Of |
include,: |
R11288 |
T16277 |
T16275 |
arg2Of |
MHB1457,include |
R11289 |
T16277 |
T16278 |
arg1Of |
MHB1457,"," |
R1129 |
T2014 |
T2011 |
arg2Of |
gene,and |
R11290 |
T16277 |
T16285 |
arg1Of |
MHB1457,; |
R11291 |
T16279 |
T16278 |
arg2Of |
5′CCGCTCGAGTGCTAGGCAAACACTCA3′,"," |
R11292 |
T16279 |
T16280 |
arg1Of |
5′CCGCTCGAGTGCTAGGCAAACACTCA3′,( |
R11293 |
T16283 |
T16280 |
arg2Of |
−2052,( |
R11294 |
T16283 |
T16281 |
arg1Of |
−2052,−2077 |
R11295 |
T16283 |
T16282 |
arg1Of |
−2052,to |
R11296 |
T16284 |
T16280 |
arg3Of |
),( |
R11297 |
T16286 |
T16285 |
arg2Of |
MHB1503,; |
R11298 |
T16286 |
T16287 |
arg1Of |
MHB1503,"," |
R11299 |
T16286 |
T16294 |
arg1Of |
MHB1503,; |
R113 |
T324 |
T323 |
arg1Of |
globin,ɛy |
R1130 |
T2014 |
T2012 |
arg1Of |
gene,the |
R11300 |
T16288 |
T16287 |
arg2Of |
5′CCGCTCGAGTCTCTACACTGTCACTCCCTG3′,"," |
R11301 |
T16288 |
T16289 |
arg1Of |
5′CCGCTCGAGTCTCTACACTGTCACTCCCTG3′,( |
R11302 |
T16292 |
T16289 |
arg2Of |
−605,( |
R11303 |
T16292 |
T16290 |
arg1Of |
−605,−634 |
R11304 |
T16292 |
T16291 |
arg1Of |
−605,to |
R11305 |
T16293 |
T16289 |
arg3Of |
),( |
R11306 |
T16295 |
T16294 |
arg2Of |
MHB1505,; |
R11307 |
T16295 |
T16296 |
arg1Of |
MHB1505,"," |
R11308 |
T16295 |
T16303 |
arg1Of |
MHB1505,; |
R11309 |
T16297 |
T16296 |
arg2Of |
5′CCGCTCGAGGGAGCCAAAAAAAGAATGC3′,"," |
R1131 |
T2014 |
T2013 |
arg1Of |
gene,Sox6 |
R11310 |
T16297 |
T16298 |
arg1Of |
5′CCGCTCGAGGGAGCCAAAAAAAGAATGC3′,( |
R11311 |
T16301 |
T16298 |
arg2Of |
−169,( |
R11312 |
T16301 |
T16299 |
arg1Of |
−169,−197 |
R11313 |
T16301 |
T16300 |
arg1Of |
−169,to |
R11314 |
T16302 |
T16298 |
arg3Of |
),( |
R11315 |
T16304 |
T16303 |
arg2Of |
MHB1506,; |
R11316 |
T16304 |
T16305 |
arg1Of |
MHB1506,"," |
R11317 |
T16304 |
T16312 |
arg1Of |
MHB1506,; |
R11318 |
T16306 |
T16305 |
arg2Of |
5′CCGCTCGAGCTGACCAATGGCTTCAAAG3′,"," |
R11319 |
T16306 |
T16307 |
arg1Of |
5′CCGCTCGAGCTGACCAATGGCTTCAAAG3′,( |
R1132 |
T2014 |
T2015 |
arg1Of |
gene,( |
R11320 |
T16310 |
T16307 |
arg2Of |
−58,( |
R11321 |
T16310 |
T16308 |
arg1Of |
−58,−85 |
R11322 |
T16310 |
T16309 |
arg1Of |
−58,to |
R11323 |
T16311 |
T16307 |
arg3Of |
),( |
R11324 |
T16313 |
T16314 |
arg1Of |
MHB1532,"," |
R11325 |
T16313 |
T16322 |
arg1Of |
MHB1532,and |
R11326 |
T16315 |
T16314 |
arg2Of |
5′CCGCTCGAGAATGCAGAACAAAGGGTCAGA3′,"," |
R11327 |
T16315 |
T16316 |
arg1Of |
5′CCGCTCGAGAATGCAGAACAAAGGGTCAGA3′,( |
R11328 |
T16319 |
T16316 |
arg2Of |
−34,( |
R11329 |
T16319 |
T16317 |
arg1Of |
−34,−63 |
R1133 |
T2019 |
T2015 |
arg2Of |
gene,( |
R11330 |
T16319 |
T16318 |
arg1Of |
−34,to |
R11331 |
T16320 |
T16316 |
arg3Of |
),( |
R11332 |
T16322 |
T16312 |
arg2Of |
and,; |
R11333 |
T16322 |
T16321 |
arg1Of |
and,; |
R11334 |
T16323 |
T16322 |
arg2Of |
MHB1507,and |
R11335 |
T16323 |
T16324 |
arg1Of |
MHB1507,"," |
R11336 |
T16326 |
T16324 |
arg2Of |
3′,"," |
R11337 |
T16326 |
T16325 |
arg1Of |
3′,5′CCGCTCGAGGTCTGCGAAGAATAAAAGGC |
R11338 |
T16326 |
T16327 |
arg1Of |
3′,( |
R11339 |
T16330 |
T16327 |
arg2Of |
−9,( |
R1134 |
T2019 |
T2016 |
arg1Of |
gene,and |
R11340 |
T16330 |
T16328 |
arg1Of |
−9,−37 |
R11341 |
T16330 |
T16329 |
arg1Of |
−9,to |
R11342 |
T16331 |
T16327 |
arg3Of |
),( |
R11343 |
T16334 |
T16332 |
arg1Of |
primers,All |
R11344 |
T16334 |
T16333 |
arg1Of |
primers,forward |
R11345 |
T16334 |
T16335 |
arg1Of |
primers,were |
R11346 |
T16334 |
T16336 |
arg2Of |
primers,used |
R11347 |
T16336 |
T16335 |
arg2Of |
used,were |
R11348 |
T16336 |
T16337 |
arg1Of |
used,in |
R11349 |
T16336 |
T16345 |
arg1Of |
used,: |
R1135 |
T2019 |
T2017 |
arg1Of |
gene,no |
R11350 |
T16336 |
T16346 |
arg1Of |
used,MHB1477 |
R11351 |
T16338 |
T16337 |
arg2Of |
combination,in |
R11352 |
T16338 |
T16339 |
arg1Of |
combination,with |
R11353 |
T16344 |
T16339 |
arg2Of |
site,with |
R11354 |
T16344 |
T16340 |
arg1Of |
site,the |
R11355 |
T16344 |
T16341 |
arg1Of |
site,reverse |
R11356 |
T16344 |
T16342 |
arg1Of |
site,primer |
R11357 |
T16344 |
T16343 |
arg1Of |
site,HindIII |
R11358 |
T16346 |
T16347 |
arg1Of |
MHB1477,"," |
R11359 |
T16348 |
T16347 |
arg2Of |
5′CGGAAGCTTGGGAGGTTGCTGGTGA3′,"," |
R1136 |
T2019 |
T2018 |
arg1Of |
gene,other |
R11360 |
T16348 |
T16349 |
arg1Of |
5′CGGAAGCTTGGGAGGTTGCTGGTGA3′,( |
R11361 |
T16352 |
T16349 |
arg2Of |
+20,( |
R11362 |
T16352 |
T16350 |
arg1Of |
+20,+45 |
R11363 |
T16352 |
T16351 |
arg1Of |
+20,to |
R11364 |
T16353 |
T16349 |
arg3Of |
),( |
R11365 |
T16354 |
T16355 |
arg1Of |
Sox6-pcDNA3.1,[ |
R11366 |
T16354 |
T16358 |
arg1Of |
Sox6-pcDNA3.1,was |
R11367 |
T16354 |
T16359 |
arg2Of |
Sox6-pcDNA3.1,used |
R11368 |
T16354 |
T16361 |
arg1Of |
Sox6-pcDNA3.1,overexpress |
R11369 |
T16356 |
T16355 |
arg2Of |
15,[ |
R1137 |
T2019 |
T2020 |
arg1Of |
gene,within |
R11370 |
T16357 |
T16355 |
arg3Of |
],[ |
R11371 |
T16359 |
T16358 |
arg2Of |
used,was |
R11372 |
T16361 |
T16359 |
arg3Of |
overexpress,used |
R11373 |
T16361 |
T16360 |
arg1Of |
overexpress,to |
R11374 |
T16362 |
T16361 |
arg2Of |
Sox6,overexpress |
R11375 |
T16365 |
T16363 |
arg1Of |
version,A |
R11376 |
T16365 |
T16364 |
arg2Of |
version,truncated |
R11377 |
T16365 |
T16366 |
arg1Of |
version,of |
R11378 |
T16365 |
T16379 |
arg1Of |
version,was |
R11379 |
T16365 |
T16380 |
arg2Of |
version,generated |
R1138 |
T2022 |
T2020 |
arg2Of |
nucleotides,within |
R11380 |
T16370 |
T16366 |
arg2Of |
construct,of |
R11381 |
T16370 |
T16367 |
arg1Of |
construct,the |
R11382 |
T16370 |
T16368 |
arg1Of |
construct,Sox6 |
R11383 |
T16370 |
T16369 |
arg1Of |
construct,overexpression |
R11384 |
T16370 |
T16371 |
arg1Of |
construct,( |
R11385 |
T16370 |
T16374 |
arg1Of |
construct,that |
R11386 |
T16370 |
T16375 |
arg1Of |
construct,lacks |
R11387 |
T16372 |
T16371 |
arg2Of |
Sox6-ΔHMG-pcDNA3.1,( |
R11388 |
T16373 |
T16371 |
arg3Of |
),( |
R11389 |
T16378 |
T16375 |
arg2Of |
domain,lacks |
R1139 |
T2022 |
T2021 |
arg1Of |
nucleotides,"50,000" |
R11390 |
T16378 |
T16376 |
arg1Of |
domain,the |
R11391 |
T16378 |
T16377 |
arg1Of |
domain,HMG |
R11392 |
T16380 |
T16379 |
arg2Of |
generated,was |
R11393 |
T16380 |
T16381 |
arg1Of |
generated,"," |
R11394 |
T16380 |
T16382 |
arg1Of |
generated,as |
R11395 |
T16383 |
T16382 |
arg2Of |
described,as |
R11396 |
T16385 |
T16383 |
arg1Of |
others,described |
R11397 |
T16385 |
T16384 |
arg2Of |
others,by |
R11398 |
T16385 |
T16386 |
arg1Of |
others,[ |
R11399 |
T16387 |
T16386 |
arg2Of |
32,[ |
R114 |
T324 |
T325 |
arg1Of |
globin,is |
R1140 |
T2022 |
T2023 |
arg1Of |
nucleotides,of |
R11400 |
T16388 |
T16386 |
arg3Of |
],[ |
R11401 |
T16389 |
T16390 |
arg1Of |
Mutagenesis,of |
R11402 |
T16389 |
T16399 |
arg1Of |
Mutagenesis,were |
R11403 |
T16389 |
T16400 |
arg2Of |
Mutagenesis,done |
R11404 |
T16394 |
T16390 |
arg2Of |
sites,of |
R11405 |
T16394 |
T16391 |
arg1Of |
sites,Sox/Sox6 |
R11406 |
T16394 |
T16392 |
arg1Of |
sites,consensus |
R11407 |
T16394 |
T16393 |
arg1Of |
sites,binding |
R11408 |
T16394 |
T16395 |
arg1Of |
sites,of |
R11409 |
T16398 |
T16395 |
arg2Of |
promoter,of |
R1141 |
T2026 |
T2023 |
arg2Of |
breakpoints,of |
R11410 |
T16398 |
T16396 |
arg1Of |
promoter,the |
R11411 |
T16398 |
T16397 |
arg1Of |
promoter,ɛy |
R11412 |
T16400 |
T16399 |
arg2Of |
done,were |
R11413 |
T16402 |
T16400 |
arg1Of |
PCR,done |
R11414 |
T16402 |
T16401 |
arg2Of |
PCR,by |
R11415 |
T16404 |
T16403 |
arg1Of |
primers,Forward |
R11416 |
T16404 |
T16405 |
arg2Of |
primers,used |
R11417 |
T16404 |
T16414 |
arg1Of |
primers,include |
R11418 |
T16407 |
T16405 |
arg3Of |
generate,used |
R11419 |
T16407 |
T16406 |
arg1Of |
generate,to |
R1142 |
T2026 |
T2024 |
arg1Of |
breakpoints,the |
R11420 |
T16413 |
T16407 |
arg2Of |
constructs,generate |
R11421 |
T16413 |
T16408 |
arg1Of |
constructs,these |
R11422 |
T16413 |
T16409 |
arg2Of |
constructs,mutagenized |
R11423 |
T16413 |
T16410 |
arg1Of |
constructs,ɛy |
R11424 |
T16413 |
T16411 |
arg1Of |
constructs,promoter |
R11425 |
T16413 |
T16412 |
arg1Of |
constructs,reporter |
R11426 |
T16414 |
T16415 |
arg1Of |
include,: |
R11427 |
T16416 |
T16414 |
arg2Of |
MHB1661,include |
R11428 |
T16416 |
T16417 |
arg1Of |
MHB1661,"," |
R11429 |
T16416 |
T16424 |
arg1Of |
MHB1661,; |
R1143 |
T2026 |
T2025 |
arg1Of |
breakpoints,chromosomal |
R11430 |
T16418 |
T16417 |
arg2Of |
5′CCGCTCGAGAATGCAGTGCCAAGGGTCAGAACATTGTCTGCGAAG3′,"," |
R11431 |
T16418 |
T16419 |
arg1Of |
5′CCGCTCGAGAATGCAGTGCCAAGGGTCAGAACATTGTCTGCGAAG3′,( |
R11432 |
T16422 |
T16419 |
arg2Of |
−19,( |
R11433 |
T16422 |
T16420 |
arg1Of |
−19,−63 |
R11434 |
T16422 |
T16421 |
arg1Of |
−19,to |
R11435 |
T16423 |
T16419 |
arg3Of |
),( |
R11436 |
T16425 |
T16426 |
arg1Of |
MHB1662,"," |
R11437 |
T16425 |
T16434 |
arg1Of |
MHB1662,and |
R11438 |
T16427 |
T16426 |
arg2Of |
5′CCGCTCGAGAATGCAGAACAAAGGGTCAGATGAGTGTCTGCGAAGAA3′,"," |
R11439 |
T16427 |
T16428 |
arg1Of |
5′CCGCTCGAGAATGCAGAACAAAGGGTCAGATGAGTGTCTGCGAAGAA3′,( |
R1144 |
T2027 |
T2015 |
arg3Of |
),( |
R11440 |
T16431 |
T16428 |
arg2Of |
−16,( |
R11441 |
T16431 |
T16429 |
arg1Of |
−16,−63 |
R11442 |
T16431 |
T16430 |
arg1Of |
−16,to |
R11443 |
T16432 |
T16428 |
arg3Of |
),( |
R11444 |
T16434 |
T16424 |
arg2Of |
and,; |
R11445 |
T16434 |
T16433 |
arg1Of |
and,; |
R11446 |
T16435 |
T16434 |
arg2Of |
MHB1663,and |
R11447 |
T16435 |
T16436 |
arg1Of |
MHB1663,"," |
R11448 |
T16438 |
T16436 |
arg2Of |
3′,"," |
R11449 |
T16438 |
T16437 |
arg1Of |
3′,5′CCGCTCGAGAATGCATGCCAAGGGTCAGATGAGTGTCTGCGAAGAA |
R1145 |
T2029 |
T2028 |
arg2Of |
14,[ |
R11450 |
T16438 |
T16439 |
arg1Of |
3′,( |
R11451 |
T16442 |
T16439 |
arg2Of |
−18,( |
R11452 |
T16442 |
T16440 |
arg1Of |
−18,−63 |
R11453 |
T16442 |
T16441 |
arg1Of |
−18,to |
R11454 |
T16443 |
T16439 |
arg3Of |
),( |
R1146 |
T2030 |
T2028 |
arg3Of |
],[ |
R1147 |
T2034 |
T2032 |
arg1Of |
gene,the |
R1148 |
T2034 |
T2033 |
arg1Of |
gene,p |
R1149 |
T2034 |
T2035 |
arg1Of |
gene,functions |
R115 |
T324 |
T327 |
arg2Of |
globin,expressed |
R1150 |
T2035 |
T2031 |
arg2Of |
functions,Because |
R1151 |
T2035 |
T2036 |
arg1Of |
functions,solely |
R1152 |
T2035 |
T2037 |
arg1Of |
functions,in |
R1153 |
T2038 |
T2037 |
arg2Of |
pigmentation,in |
R1154 |
T2038 |
T2039 |
arg1Of |
pigmentation,[ |
R1155 |
T2040 |
T2039 |
arg2Of |
16,[ |
R1156 |
T2041 |
T2039 |
arg3Of |
],[ |
R1157 |
T2046 |
T2043 |
arg1Of |
factor,the |
R1158 |
T2046 |
T2044 |
arg1Of |
factor,Sox6 |
R1159 |
T2046 |
T2045 |
arg1Of |
factor,transcription |
R116 |
T327 |
T325 |
arg2Of |
expressed,is |
R1160 |
T2046 |
T2047 |
arg1Of |
factor,is |
R1161 |
T2046 |
T2048 |
arg2Of |
factor,implicated |
R1162 |
T2048 |
T2031 |
arg1Of |
implicated,Because |
R1163 |
T2048 |
T2042 |
arg1Of |
implicated,"," |
R1164 |
T2048 |
T2047 |
arg2Of |
implicated,is |
R1165 |
T2048 |
T2049 |
arg1Of |
implicated,in |
R1166 |
T2052 |
T2049 |
arg2Of |
phenotypes,in |
R1167 |
T2052 |
T2050 |
arg1Of |
phenotypes,all |
R1168 |
T2052 |
T2051 |
arg1Of |
phenotypes,other |
R1169 |
T2057 |
T2053 |
arg2Of |
proteins,Among |
R117 |
T327 |
T326 |
arg1Of |
expressed,persistently |
R1170 |
T2057 |
T2054 |
arg1Of |
proteins,the |
R1171 |
T2057 |
T2055 |
arg1Of |
proteins,HMG |
R1172 |
T2057 |
T2056 |
arg1Of |
proteins,box |
R1173 |
T2057 |
T2059 |
arg2Of |
proteins,related |
R1174 |
T2059 |
T2058 |
arg1Of |
related,distantly |
R1175 |
T2059 |
T2060 |
arg1Of |
related,to |
R1176 |
T2061 |
T2060 |
arg2Of |
Sry,to |
R1177 |
T2061 |
T2062 |
arg1Of |
Sry,( |
R1178 |
T2065 |
T2062 |
arg2Of |
member,( |
R1179 |
T2065 |
T2063 |
arg1Of |
member,the |
R118 |
T327 |
T329 |
arg1Of |
expressed,and |
R1180 |
T2065 |
T2064 |
arg1Of |
member,first |
R1181 |
T2065 |
T2066 |
arg2Of |
member,identified |
R1182 |
T2066 |
T2067 |
arg1Of |
identified,of |
R1183 |
T2072 |
T2067 |
arg2Of |
family,of |
R1184 |
T2072 |
T2068 |
arg1Of |
family,the |
R1185 |
T2072 |
T2069 |
arg1Of |
family,Sox |
R1186 |
T2072 |
T2070 |
arg1Of |
family,transcription |
R1187 |
T2072 |
T2071 |
arg1Of |
family,factor |
R1188 |
T2073 |
T2062 |
arg3Of |
),( |
R1189 |
T2074 |
T2053 |
arg1Of |
that,Among |
R119 |
T329 |
T316 |
arg1Of |
and,In |
R1190 |
T2074 |
T2076 |
arg1Of |
that,bind |
R1191 |
T2074 |
T2090 |
arg1Of |
that,are |
R1192 |
T2076 |
T2075 |
arg1Of |
bind,similarly |
R1193 |
T2076 |
T2077 |
arg1Of |
bind,to |
R11937 |
T17191 |
T17192 |
arg1Of |
Quantitation,of |
R11938 |
T17194 |
T17192 |
arg2Of |
mRNA,of |
R11939 |
T17194 |
T17193 |
arg1Of |
mRNA,globin |
R1194 |
T2076 |
T2086 |
arg1Of |
bind,without |
R11940 |
T17195 |
T17196 |
arg1Of |
RNA,was |
R11941 |
T17198 |
T17197 |
arg1Of |
reverse,first |
R11942 |
T17201 |
T17196 |
arg2Of |
cDNA,was |
R11943 |
T17201 |
T17198 |
arg1Of |
cDNA,reverse |
R11944 |
T17201 |
T17199 |
arg2Of |
cDNA,transcribed |
R11945 |
T17201 |
T17200 |
arg1Of |
cDNA,to |
R11946 |
T17202 |
T17203 |
arg1Of |
Primers,for |
R11947 |
T17202 |
T17210 |
arg1Of |
Primers,were |
R11948 |
T17202 |
T17211 |
arg2Of |
Primers,obtained |
R11949 |
T17206 |
T17203 |
arg2Of |
amplification,for |
R1195 |
T2077 |
T2085 |
arg1Of |
to,but |
R11950 |
T17206 |
T17204 |
arg1Of |
amplification,cDNA |
R11951 |
T17206 |
T17205 |
arg1Of |
amplification,PCR |
R11952 |
T17206 |
T17207 |
arg1Of |
amplification,of |
R11953 |
T17209 |
T17207 |
arg2Of |
genes,of |
R11954 |
T17209 |
T17208 |
arg1Of |
genes,globin |
R11955 |
T17211 |
T17210 |
arg2Of |
obtained,were |
R11956 |
T17211 |
T17212 |
arg1Of |
obtained,from |
R11957 |
T17213 |
T17212 |
arg2Of |
Primerbank,from |
R11958 |
T17213 |
T17214 |
arg1Of |
Primerbank,[ |
R11959 |
T17215 |
T17214 |
arg2Of |
51,[ |
R1196 |
T2080 |
T2081 |
arg1Of |
groove,and |
R11960 |
T17216 |
T17214 |
arg3Of |
],[ |
R11961 |
T17218 |
T17217 |
arg1Of |
primers,All |
R11962 |
T17218 |
T17219 |
arg1Of |
primers,were |
R11963 |
T17218 |
T17220 |
arg2Of |
primers,searched |
R11964 |
T17220 |
T17219 |
arg2Of |
searched,were |
R11965 |
T17220 |
T17221 |
arg1Of |
searched,against |
R11966 |
T17220 |
T17225 |
modOf |
searched,to |
R11967 |
T17224 |
T17221 |
arg2Of |
database,against |
R11968 |
T17224 |
T17222 |
arg1Of |
database,the |
R11969 |
T17224 |
T17223 |
arg1Of |
database,NCBI |
R1197 |
T2082 |
T2081 |
arg2Of |
bend,and |
R11970 |
T17226 |
T17225 |
arg1Of |
confirm,to |
R11971 |
T17227 |
T17226 |
arg2Of |
specificity,confirm |
R11972 |
T17230 |
T17228 |
arg1Of |
globin,For |
R11973 |
T17230 |
T17229 |
arg1Of |
globin,ɛy |
R11974 |
T17230 |
T17231 |
arg1Of |
globin,: |
R11975 |
T17232 |
T17231 |
arg2Of |
MHB1666,: |
R11976 |
T17232 |
T17233 |
arg1Of |
MHB1666,"," |
R11977 |
T17232 |
T17238 |
arg1Of |
MHB1666,"," |
R11978 |
T17234 |
T17236 |
arg1Of |
5′TGGCCTGTGGAGTAAGGTCAA3′,and |
R11979 |
T17236 |
T17233 |
arg2Of |
and,"," |
R1198 |
T2083 |
T2077 |
arg2Of |
DNA,to |
R11980 |
T17236 |
T17235 |
arg1Of |
and,; |
R11981 |
T17237 |
T17236 |
arg2Of |
MHB1667,and |
R11982 |
T17239 |
T17238 |
arg2Of |
5′GAAGCAGAGGACAAGTTCCCA3′,"," |
R11983 |
T17242 |
T17240 |
arg1Of |
globin,For |
R11984 |
T17242 |
T17241 |
arg1Of |
globin,ζ |
R11985 |
T17242 |
T17243 |
arg1Of |
globin,: |
R11986 |
T17244 |
T17243 |
arg2Of |
MHB1668,: |
R11987 |
T17244 |
T17245 |
arg1Of |
MHB1668,"," |
R11988 |
T17244 |
T17250 |
arg1Of |
MHB1668,"," |
R11989 |
T17246 |
T17248 |
arg1Of |
5′CTACCCCCAGACGAAGACCTA3′,and |
R1199 |
T2083 |
T2078 |
arg1Of |
DNA,the |
R11990 |
T17248 |
T17245 |
arg2Of |
and,"," |
R11991 |
T17248 |
T17247 |
arg1Of |
and,; |
R11992 |
T17249 |
T17248 |
arg2Of |
MHB1669,and |
R11993 |
T17251 |
T17250 |
arg2Of |
5′CTTAACCGCATCCCCTACGG3′,"," |
R11994 |
T17254 |
T17252 |
arg1Of |
globin,For |
R11995 |
T17254 |
T17253 |
arg1Of |
globin,βH1 |
R11996 |
T17254 |
T17255 |
arg1Of |
globin,: |
R11997 |
T17256 |
T17255 |
arg2Of |
MHB1672,: |
R11998 |
T17256 |
T17257 |
arg1Of |
MHB1672,"," |
R11999 |
T17256 |
T17262 |
arg1Of |
MHB1672,"," |
R120 |
T329 |
T322 |
arg1Of |
and,"," |
R1200 |
T2083 |
T2079 |
arg1Of |
DNA,minor |
R12000 |
T17258 |
T17260 |
arg1Of |
5′TGGACAACCTCAAGGAGACC3′,and |
R12001 |
T17260 |
T17257 |
arg2Of |
and,"," |
R12002 |
T17260 |
T17259 |
arg1Of |
and,; |
R12003 |
T17261 |
T17260 |
arg2Of |
MHB1673,and |
R12004 |
T17263 |
T17262 |
arg2Of |
5′ACCTCTGGGGTGAATTCCTT3′,"," |
R12005 |
T17266 |
T17265 |
arg1Of |
globin,βmaj/min |
R12006 |
T17266 |
T17267 |
arg1Of |
globin,: |
R12007 |
T17267 |
T17264 |
arg1Of |
:,For |
R12008 |
T17267 |
T17269 |
arg1Of |
:,: |
R12009 |
T17268 |
T17267 |
arg2Of |
MHB1674,: |
R1201 |
T2083 |
T2080 |
arg1Of |
DNA,groove |
R12010 |
T17270 |
T17272 |
arg1Of |
5′ATGGCCTGAATCACTTGGAC3′,and |
R12011 |
T17272 |
T17271 |
arg1Of |
and,; |
R12012 |
T17273 |
T17272 |
arg2Of |
MHB1675,and |
R12013 |
T17273 |
T17274 |
arg1Of |
MHB1675,"," |
R12014 |
T17275 |
T17274 |
arg2Of |
5′ACGATCATATTGCCCAGGAG3′,"," |
R12015 |
T17276 |
T17284 |
arg1Of |
Using,( |
R12016 |
T17281 |
T17276 |
arg2Of |
kit,Using |
R12017 |
T17281 |
T17277 |
arg1Of |
kit,the |
R12018 |
T17281 |
T17278 |
arg1Of |
kit,SYBR |
R12019 |
T17281 |
T17279 |
arg1Of |
kit,green |
R1202 |
T2083 |
T2082 |
arg1Of |
DNA,bend |
R12020 |
T17281 |
T17280 |
arg1Of |
kit,supermix |
R12021 |
T17281 |
T17282 |
arg1Of |
kit,with |
R12022 |
T17283 |
T17282 |
arg2Of |
ROX,with |
R12023 |
T17285 |
T17286 |
arg1Of |
Bio-Rad,"," |
R12024 |
T17286 |
T17288 |
arg1Of |
",","," |
R12025 |
T17287 |
T17286 |
arg2Of |
Hercules,"," |
R12026 |
T17288 |
T17290 |
arg1Of |
",","," |
R12027 |
T17289 |
T17288 |
arg2Of |
California,"," |
R12028 |
T17290 |
T17284 |
arg2Of |
",",( |
R12029 |
T17292 |
T17290 |
arg2Of |
States,"," |
R1203 |
T2085 |
T2084 |
arg1Of |
but,"," |
R12030 |
T17292 |
T17291 |
arg1Of |
States,United |
R12031 |
T17293 |
T17284 |
arg3Of |
),( |
R12032 |
T17296 |
T17295 |
arg1Of |
amplification,PCR |
R12033 |
T17296 |
T17297 |
arg1Of |
amplification,was |
R12034 |
T17296 |
T17298 |
arg2Of |
amplification,run |
R12035 |
T17298 |
T17276 |
modOf |
run,Using |
R12036 |
T17298 |
T17294 |
arg1Of |
run,"," |
R12037 |
T17298 |
T17297 |
arg2Of |
run,was |
R12038 |
T17298 |
T17299 |
arg1Of |
run,on |
R12039 |
T17301 |
T17299 |
arg2Of |
ABI7000,on |
R1204 |
T2086 |
T2085 |
arg2Of |
without,but |
R12040 |
T17301 |
T17300 |
arg1Of |
ABI7000,an |
R12041 |
T17301 |
T17302 |
arg1Of |
ABI7000,( |
R12042 |
T17301 |
T17314 |
arg1Of |
ABI7000,at |
R12043 |
T17304 |
T17303 |
arg1Of |
Biosystems,Applied |
R12044 |
T17304 |
T17305 |
arg1Of |
Biosystems,"," |
R12045 |
T17305 |
T17308 |
arg1Of |
",","," |
R12046 |
T17307 |
T17305 |
arg2Of |
City,"," |
R12047 |
T17307 |
T17306 |
arg1Of |
City,Foster |
R12048 |
T17308 |
T17310 |
arg1Of |
",","," |
R12049 |
T17309 |
T17308 |
arg2Of |
California,"," |
R1205 |
T2088 |
T2086 |
arg2Of |
specificity,without |
R12050 |
T17310 |
T17302 |
arg2Of |
",",( |
R12051 |
T17312 |
T17310 |
arg2Of |
States,"," |
R12052 |
T17312 |
T17311 |
arg1Of |
States,United |
R12053 |
T17313 |
T17302 |
arg3Of |
),( |
R12054 |
T17316 |
T17317 |
arg1Of |
University,of |
R12055 |
T17318 |
T17317 |
arg2Of |
Arizona,of |
R12056 |
T17320 |
T17314 |
arg2Of |
facility,at |
R12057 |
T17320 |
T17315 |
arg1Of |
facility,the |
R12058 |
T17320 |
T17316 |
arg1Of |
facility,University |
R12059 |
T17320 |
T17319 |
arg1Of |
facility,core |
R1206 |
T2088 |
T2087 |
arg1Of |
specificity,sequence |
R12060 |
T17322 |
T17321 |
arg1Of |
PCR,All |
R12061 |
T17322 |
T17323 |
arg1Of |
PCR,was |
R12062 |
T17322 |
T17324 |
arg2Of |
PCR,performed |
R12063 |
T17324 |
T17323 |
arg2Of |
performed,was |
R12064 |
T17324 |
T17325 |
arg1Of |
performed,in |
R12065 |
T17328 |
T17325 |
arg2Of |
reaction,in |
R12066 |
T17328 |
T17326 |
arg1Of |
reaction,a |
R12067 |
T17328 |
T17327 |
arg1Of |
reaction,25-μl |
R12068 |
T17328 |
T17329 |
arg1Of |
reaction,with |
R12069 |
T17334 |
T17329 |
arg2Of |
supermix,with |
R1207 |
T2090 |
T2089 |
arg1Of |
are,"," |
R12070 |
T17334 |
T17330 |
arg1Of |
supermix,12.5 |
R12071 |
T17334 |
T17331 |
arg1Of |
supermix,μl |
R12072 |
T17334 |
T17332 |
arg1Of |
supermix,SYBR |
R12073 |
T17334 |
T17333 |
arg1Of |
supermix,green |
R12074 |
T17337 |
T17335 |
arg1Of |
levels,GAPDH |
R12075 |
T17337 |
T17336 |
arg1Of |
levels,mRNA |
R12076 |
T17337 |
T17338 |
arg1Of |
levels,were |
R12077 |
T17337 |
T17339 |
arg2Of |
levels,used |
R12078 |
T17339 |
T17338 |
arg2Of |
used,were |
R12079 |
T17339 |
T17340 |
arg1Of |
used,as |
R1208 |
T2090 |
T2098 |
arg1Of |
are,[ |
R12080 |
T17341 |
T17340 |
arg2Of |
control,as |
R12081 |
T17341 |
T17342 |
arg1Of |
control,for |
R12082 |
T17344 |
T17342 |
arg2Of |
RNA,for |
R12083 |
T17344 |
T17343 |
arg1Of |
RNA,input |
R12084 |
T17347 |
T17345 |
arg1Of |
analyses,Standard |
R12085 |
T17347 |
T17346 |
arg1Of |
analyses,curve |
R12086 |
T17347 |
T17348 |
arg1Of |
analyses,were |
R12087 |
T17347 |
T17349 |
arg2Of |
analyses,performed |
R12088 |
T17349 |
T17348 |
arg2Of |
performed,were |
R12089 |
T17351 |
T17349 |
arg3Of |
test,performed |
R1209 |
T2093 |
T2092 |
arg1Of |
expressed,ubiquitously |
R12090 |
T17351 |
T17350 |
arg1Of |
test,to |
R12091 |
T17353 |
T17351 |
arg2Of |
efficiency,test |
R12092 |
T17353 |
T17352 |
arg1Of |
efficiency,the |
R12093 |
T17353 |
T17354 |
arg1Of |
efficiency,of |
R12094 |
T17356 |
T17354 |
arg2Of |
amplifications,of |
R12095 |
T17356 |
T17355 |
arg1Of |
amplifications,the |
R12096 |
T17357 |
T17358 |
arg1Of |
Triplicates,were |
R12097 |
T17357 |
T17359 |
arg2Of |
Triplicates,done |
R12098 |
T17359 |
T17358 |
arg2Of |
done,were |
R12099 |
T17359 |
T17360 |
arg1Of |
done,for |
R121 |
T329 |
T328 |
arg1Of |
and,"," |
R1210 |
T2094 |
T2093 |
arg1Of |
HMG1,expressed |
R12100 |
T17363 |
T17360 |
arg2Of |
reaction,for |
R12101 |
T17363 |
T17361 |
arg1Of |
reaction,each |
R12102 |
T17363 |
T17362 |
arg1Of |
reaction,PCR |
R12103 |
T17366 |
T17364 |
arg1Of |
values,Relative |
R12104 |
T17366 |
T17365 |
arg1Of |
values,quantitative |
R12105 |
T17366 |
T17367 |
arg1Of |
values,were |
R12106 |
T17366 |
T17368 |
arg2Of |
values,calculated |
R12107 |
T17366 |
T17381 |
arg1Of |
values,normalized |
R12108 |
T17368 |
T17367 |
arg2Of |
calculated,were |
R12109 |
T17368 |
T17369 |
arg1Of |
calculated,in |
R1211 |
T2094 |
T2095 |
arg1Of |
HMG1,and |
R12110 |
T17368 |
T17380 |
arg1Of |
calculated,and |
R12111 |
T17375 |
T17369 |
arg2Of |
Software,in |
R12112 |
T17375 |
T17370 |
arg1Of |
Software,the |
R12113 |
T17375 |
T17371 |
arg1Of |
Software,ABI |
R12114 |
T17375 |
T17372 |
arg1Of |
Software,Prism |
R12115 |
T17375 |
T17373 |
arg1Of |
Software,7000 |
R12116 |
T17375 |
T17374 |
arg1Of |
Software,SDS |
R12117 |
T17375 |
T17376 |
arg1Of |
Software,( |
R12118 |
T17378 |
T17376 |
arg2Of |
Biosystems,( |
R12119 |
T17378 |
T17377 |
arg1Of |
Biosystems,Applied |
R1212 |
T2095 |
T2090 |
arg2Of |
and,are |
R12120 |
T17379 |
T17376 |
arg3Of |
),( |
R12121 |
T17381 |
T17380 |
arg2Of |
normalized,and |
R12122 |
T17381 |
T17382 |
arg1Of |
normalized,to |
R12123 |
T17383 |
T17382 |
arg2Of |
GAPDH,to |
R12124 |
T17383 |
T17384 |
arg1Of |
GAPDH,in |
R12125 |
T17386 |
T17384 |
arg2Of |
Excel,in |
R12126 |
T17386 |
T17385 |
arg1Of |
Excel,Microsoft |
R12127 |
T17386 |
T17387 |
arg1Of |
Excel,( |
R12128 |
T17388 |
T17389 |
arg1Of |
Redmond,"," |
R12129 |
T17389 |
T17391 |
arg1Of |
",","," |
R1213 |
T2095 |
T2091 |
arg1Of |
and,the |
R12130 |
T17390 |
T17389 |
arg2Of |
Washington,"," |
R12131 |
T17392 |
T17391 |
arg2Of |
United,"," |
R12132 |
T17393 |
T17387 |
arg2Of |
States,( |
R12133 |
T17393 |
T17388 |
arg1Of |
States,Redmond |
R12134 |
T17393 |
T17390 |
arg1Of |
States,Washington |
R12135 |
T17393 |
T17392 |
arg1Of |
States,United |
R12136 |
T17394 |
T17387 |
arg3Of |
),( |
R1214 |
T2097 |
T2095 |
arg2Of |
proteins,and |
R1215 |
T2097 |
T2096 |
arg1Of |
proteins,HMG2 |
R1216 |
T2099 |
T2098 |
arg2Of |
17,[ |
R1217 |
T2100 |
T2098 |
arg3Of |
],[ |
R1218 |
T2101 |
T2102 |
arg1Of |
Modulation,of |
R1219 |
T2101 |
T2105 |
arg1Of |
Modulation,by |
R122 |
T331 |
T330 |
arg2Of |
numbers,increased |
R1220 |
T2101 |
T2111 |
arg1Of |
Modulation,can |
R1221 |
T2101 |
T2112 |
arg1Of |
Modulation,mediate |
R1222 |
T2101 |
T2123 |
arg1Of |
Modulation,bringing |
R1223 |
T2104 |
T2102 |
arg2Of |
structure,of |
R1224 |
T2104 |
T2103 |
arg1Of |
structure,DNA |
R1225 |
T2110 |
T2105 |
arg2Of |
proteins,by |
R1226 |
T2110 |
T2106 |
arg1Of |
proteins,these |
R1227 |
T2110 |
T2107 |
arg1Of |
proteins,and |
R1228 |
T2110 |
T2108 |
arg1Of |
proteins,other |
R1229 |
T2110 |
T2109 |
arg1Of |
proteins,HMG |
R123 |
T331 |
T332 |
arg1Of |
numbers,of |
R1230 |
T2112 |
T2111 |
arg2Of |
mediate,can |
R1231 |
T2112 |
T2116 |
arg1Of |
mediate,on |
R1232 |
T2112 |
T2122 |
arg1Of |
mediate,by |
R1233 |
T2115 |
T2112 |
arg2Of |
function,mediate |
R1234 |
T2115 |
T2113 |
arg1Of |
function,long-range |
R1235 |
T2115 |
T2114 |
arg1Of |
function,enhancer |
R1236 |
T2118 |
T2119 |
arg1Of |
DNA,and |
R1237 |
T2119 |
T2116 |
arg2Of |
and,on |
R1238 |
T2119 |
T2117 |
arg1Of |
and,both |
R12381 |
T17767 |
T17766 |
arg1Of |
situ,In |
R12382 |
T17768 |
T17767 |
arg1Of |
hybridization,situ |
R12383 |
T17770 |
T17769 |
arg1Of |
probes,Antisense |
R12384 |
T17770 |
T17771 |
arg1Of |
probes,were |
R12385 |
T17770 |
T17772 |
arg2Of |
probes,designed |
R12386 |
T17772 |
T17771 |
arg2Of |
designed,were |
R12387 |
T17772 |
T17773 |
arg1Of |
designed,to |
R12388 |
T17777 |
T17774 |
arg1Of |
nucleotides,murine |
R12389 |
T17777 |
T17775 |
arg1Of |
nucleotides,ɛy |
R1239 |
T2121 |
T2119 |
arg2Of |
genes,and |
R12390 |
T17777 |
T17776 |
arg1Of |
nucleotides,globin |
R12391 |
T17777 |
T17778 |
arg1Of |
nucleotides,509–584 |
R12392 |
T17777 |
T17779 |
arg1Of |
nucleotides,; |
R12393 |
T17779 |
T17773 |
arg2Of |
;,to |
R12394 |
T17782 |
T17780 |
arg1Of |
nucleotides,βmaj |
R12395 |
T17782 |
T17781 |
arg1Of |
nucleotides,globin |
R12396 |
T17782 |
T17783 |
arg1Of |
nucleotides,458–549 |
R12397 |
T17782 |
T17785 |
arg1Of |
nucleotides,and |
R12398 |
T17785 |
T17779 |
arg2Of |
and,; |
R12399 |
T17785 |
T17784 |
arg1Of |
and,; |
R124 |
T331 |
T336 |
arg1Of |
numbers,are |
R1240 |
T2121 |
T2120 |
arg1Of |
genes,chromatin-assembled |
R12400 |
T17788 |
T17785 |
arg2Of |
nucleotides,and |
R12401 |
T17788 |
T17786 |
arg1Of |
nucleotides,mouse |
R12402 |
T17788 |
T17787 |
arg1Of |
nucleotides,Sox6 |
R12403 |
T17788 |
T17789 |
arg1Of |
nucleotides,1353–1927 |
R12404 |
T17790 |
T17791 |
arg1Of |
Embryos,were |
R12405 |
T17790 |
T17792 |
arg2Of |
Embryos,fixed |
R12406 |
T17790 |
T17811 |
arg1Of |
Embryos,adhered |
R12407 |
T17792 |
T17791 |
arg2Of |
fixed,were |
R12408 |
T17792 |
T17793 |
arg1Of |
fixed,overnight |
R12409 |
T17792 |
T17810 |
arg1Of |
fixed,and |
R1241 |
T2123 |
T2122 |
arg2Of |
bringing,by |
R12410 |
T17795 |
T17792 |
arg1Of |
immersion,fixed |
R12411 |
T17795 |
T17794 |
arg2Of |
immersion,by |
R12412 |
T17795 |
T17796 |
arg1Of |
immersion,in |
R12413 |
T17795 |
T17800 |
arg1Of |
immersion,"," |
R12414 |
T17795 |
T17801 |
arg2Of |
immersion,embedded |
R12415 |
T17795 |
T17804 |
arg1Of |
immersion,"," |
R12416 |
T17795 |
T17805 |
arg2Of |
immersion,sectioned |
R12417 |
T17797 |
T17798 |
arg1Of |
4,% |
R12418 |
T17799 |
T17796 |
arg2Of |
paraformaldehyde,in |
R12419 |
T17799 |
T17797 |
arg1Of |
paraformaldehyde,4 |
R1242 |
T2123 |
T2124 |
arg1Of |
bringing,together |
R12420 |
T17801 |
T17802 |
arg1Of |
embedded,in |
R12421 |
T17803 |
T17802 |
arg2Of |
paraffin,in |
R12422 |
T17805 |
T17806 |
arg1Of |
sectioned,at |
R12423 |
T17808 |
T17806 |
arg2Of |
μm,at |
R12424 |
T17808 |
T17807 |
arg1Of |
μm,5 |
R12425 |
T17810 |
T17809 |
arg1Of |
and,"," |
R12426 |
T17811 |
T17810 |
arg2Of |
adhered,and |
R12427 |
T17813 |
T17811 |
arg2Of |
charge,adhered |
R12428 |
T17813 |
T17812 |
arg1Of |
charge,to |
R12429 |
T17815 |
T17813 |
arg2Of |
slides,charge |
R1243 |
T2126 |
T2123 |
arg2Of |
regions,bringing |
R12430 |
T17815 |
T17814 |
arg2Of |
slides,modified |
R12431 |
T17815 |
T17816 |
arg1Of |
slides,( |
R12432 |
T17817 |
T17818 |
arg1Of |
VWR,"," |
R12433 |
T17817 |
T17821 |
arg1Of |
VWR,"," |
R12434 |
T17820 |
T17818 |
arg2Of |
Chester,"," |
R12435 |
T17820 |
T17819 |
arg1Of |
Chester,West |
R12436 |
T17821 |
T17816 |
arg2Of |
",",( |
R12437 |
T17821 |
T17823 |
arg1Of |
",","," |
R12438 |
T17822 |
T17821 |
arg2Of |
Pennsylvania,"," |
R12439 |
T17825 |
T17823 |
arg2Of |
States,"," |
R1244 |
T2126 |
T2125 |
arg1Of |
regions,distant |
R12440 |
T17825 |
T17824 |
arg1Of |
States,United |
R12441 |
T17826 |
T17816 |
arg3Of |
),( |
R12442 |
T17827 |
T17828 |
arg1Of |
Slides,were |
R12443 |
T17827 |
T17829 |
arg2Of |
Slides,processed |
R12444 |
T17829 |
T17828 |
arg2Of |
processed,were |
R12445 |
T17829 |
T17830 |
arg1Of |
processed,for |
R12446 |
T17829 |
T17834 |
arg1Of |
processed,as |
R12447 |
T17832 |
T17831 |
arg1Of |
situ,in |
R12448 |
T17833 |
T17830 |
arg2Of |
hybridization,for |
R12449 |
T17833 |
T17832 |
arg1Of |
hybridization,situ |
R1245 |
T2126 |
T2127 |
arg1Of |
regions,of |
R12450 |
T17835 |
T17834 |
arg2Of |
described,as |
R12451 |
T17835 |
T17836 |
arg1Of |
described,[ |
R12452 |
T17835 |
T17839 |
modOf |
described,using |
R12453 |
T17837 |
T17836 |
arg2Of |
52,[ |
R12454 |
T17838 |
T17836 |
arg3Of |
],[ |
R12455 |
T17841 |
T17840 |
arg1Of |
vitro,in |
R12456 |
T17844 |
T17839 |
arg2Of |
probes,using |
R12457 |
T17844 |
T17841 |
arg1Of |
probes,vitro |
R12458 |
T17844 |
T17842 |
arg2Of |
probes,transcribed |
R12459 |
T17844 |
T17843 |
arg1Of |
probes,RNA |
R1246 |
T2128 |
T2129 |
arg1Of |
DNA,and |
R12460 |
T17844 |
T17845 |
arg2Of |
probes,labeled |
R12461 |
T17845 |
T17846 |
arg1Of |
labeled,with |
R12462 |
T17847 |
T17846 |
arg2Of |
33P,with |
R12463 |
T17848 |
T17849 |
arg1Of |
Darkfield,and |
R12464 |
T17850 |
T17849 |
arg2Of |
brightfield,and |
R12465 |
T17851 |
T17848 |
arg1Of |
images,Darkfield |
R12466 |
T17851 |
T17850 |
arg1Of |
images,brightfield |
R12467 |
T17851 |
T17852 |
arg1Of |
images,were |
R12468 |
T17851 |
T17853 |
arg2Of |
images,obtained |
R12469 |
T17853 |
T17852 |
arg2Of |
obtained,were |
R1247 |
T2129 |
T2127 |
arg2Of |
and,of |
R12470 |
T17853 |
T17854 |
arg1Of |
obtained,with |
R12471 |
T17857 |
T17856 |
arg1Of |
Optiphot,Nikon |
R12472 |
T17858 |
T17857 |
arg1Of |
microscope,Optiphot |
R12473 |
T17858 |
T17859 |
arg1Of |
microscope,( |
R12474 |
T17858 |
T17870 |
arg1Of |
microscope,and |
R12475 |
T17860 |
T17861 |
arg1Of |
Nikon,"," |
R12476 |
T17861 |
T17863 |
arg1Of |
",","," |
R12477 |
T17862 |
T17861 |
arg2Of |
Melville,"," |
R12478 |
T17863 |
T17866 |
arg1Of |
",","," |
R12479 |
T17865 |
T17863 |
arg2Of |
York,"," |
R1248 |
T2131 |
T2129 |
arg2Of |
factors,and |
R12480 |
T17865 |
T17864 |
arg1Of |
York,New |
R12481 |
T17866 |
T17859 |
arg2Of |
",",( |
R12482 |
T17868 |
T17866 |
arg2Of |
States,"," |
R12483 |
T17868 |
T17867 |
arg1Of |
States,United |
R12484 |
T17869 |
T17859 |
arg3Of |
),( |
R12485 |
T17870 |
T17854 |
arg2Of |
and,with |
R12486 |
T17870 |
T17855 |
arg1Of |
and,a |
R12487 |
T17870 |
T17875 |
arg1Of |
and,( |
R12488 |
T17874 |
T17870 |
arg2Of |
camera,and |
R12489 |
T17874 |
T17871 |
arg1Of |
camera,SPOT |
R1249 |
T2131 |
T2130 |
arg2Of |
factors,associated |
R12490 |
T17874 |
T17872 |
arg1Of |
camera,RT-Slider |
R12491 |
T17874 |
T17873 |
arg1Of |
camera,digital |
R12492 |
T17877 |
T17878 |
arg1Of |
Instruments,"," |
R12493 |
T17878 |
T17881 |
arg1Of |
",","," |
R12494 |
T17880 |
T17878 |
arg2Of |
Heights,"," |
R12495 |
T17880 |
T17879 |
arg1Of |
Heights,Sterling |
R12496 |
T17881 |
T17876 |
arg1Of |
",",Diagnostic |
R12497 |
T17881 |
T17883 |
arg1Of |
",","," |
R12498 |
T17882 |
T17881 |
arg2Of |
Michigan,"," |
R12499 |
T17883 |
T17875 |
arg2Of |
",",( |
R125 |
T331 |
T337 |
arg1Of |
numbers,present |
R1250 |
T2135 |
T2134 |
arg1Of |
proteins,HMG |
R12500 |
T17885 |
T17883 |
arg2Of |
States,"," |
R12501 |
T17885 |
T17884 |
arg1Of |
States,United |
R12502 |
T17886 |
T17875 |
arg3Of |
),( |
R12503 |
T17887 |
T17888 |
arg2Of |
Objectives,used |
R12504 |
T17887 |
T17889 |
arg1Of |
Objectives,were |
R12505 |
T17890 |
T17891 |
arg1Of |
1×,( |
R12506 |
T17890 |
T17896 |
arg1Of |
1×,and |
R12507 |
T17892 |
T17891 |
arg2Of |
NA,( |
R12508 |
T17892 |
T17893 |
arg1Of |
NA,= |
R12509 |
T17892 |
T17894 |
arg1Of |
NA,0.04 |
R1251 |
T2135 |
T2136 |
arg1Of |
proteins,have |
R12510 |
T17895 |
T17891 |
arg3Of |
),( |
R12511 |
T17896 |
T17889 |
arg2Of |
and,were |
R12512 |
T17897 |
T17896 |
arg2Of |
10×,and |
R12513 |
T17897 |
T17898 |
arg1Of |
10×,( |
R12514 |
T17899 |
T17898 |
arg2Of |
NA,( |
R12515 |
T17899 |
T17900 |
arg1Of |
NA,= |
R12516 |
T17899 |
T17901 |
arg1Of |
NA,0.5 |
R12517 |
T17902 |
T17898 |
arg3Of |
),( |
R12518 |
T17903 |
T17904 |
arg1Of |
Images,were |
R12519 |
T17903 |
T17905 |
arg2Of |
Images,processed |
R1252 |
T2135 |
T2137 |
arg1Of |
proteins,been |
R12520 |
T17903 |
T17907 |
arg2Of |
Images,pseudocolored |
R12521 |
T17903 |
T17910 |
arg2Of |
Images,combined |
R12522 |
T17905 |
T17906 |
arg1Of |
processed,"," |
R12523 |
T17906 |
T17909 |
arg1Of |
",",and |
R12524 |
T17907 |
T17906 |
arg2Of |
pseudocolored,"," |
R12525 |
T17909 |
T17904 |
arg2Of |
and,were |
R12526 |
T17909 |
T17908 |
arg1Of |
and,"," |
R12527 |
T17909 |
T17940 |
arg2Of |
and,plugins |
R12528 |
T17910 |
T17909 |
arg2Of |
combined,and |
R12529 |
T17910 |
T17911 |
modOf |
combined,using |
R1253 |
T2135 |
T2138 |
arg2Of |
proteins,shown |
R12530 |
T17912 |
T17911 |
arg2Of |
Photoshop,using |
R12531 |
T17912 |
T17913 |
arg1Of |
Photoshop,( |
R12532 |
T17914 |
T17915 |
arg1Of |
Adobe,"," |
R12533 |
T17915 |
T17918 |
arg1Of |
",","," |
R12534 |
T17917 |
T17915 |
arg2Of |
Jose,"," |
R12535 |
T17917 |
T17916 |
arg1Of |
Jose,San |
R12536 |
T17918 |
T17920 |
arg1Of |
",","," |
R12537 |
T17919 |
T17918 |
arg2Of |
California,"," |
R12538 |
T17920 |
T17913 |
arg2Of |
",",( |
R12539 |
T17922 |
T17920 |
arg2Of |
States,"," |
R1254 |
T2135 |
T2140 |
arg1Of |
proteins,modulate |
R12540 |
T17922 |
T17921 |
arg1Of |
States,United |
R12541 |
T17923 |
T17913 |
arg3Of |
),( |
R12542 |
T17924 |
T17925 |
arg1Of |
software,with |
R12543 |
T17924 |
T17940 |
arg1Of |
software,plugins |
R12544 |
T17927 |
T17925 |
arg2Of |
Pro,with |
R12545 |
T17927 |
T17926 |
arg1Of |
Pro,Fovea |
R12546 |
T17927 |
T17928 |
arg1Of |
Pro,( |
R12547 |
T17930 |
T17929 |
arg1Of |
Graphics,Reindeer |
R12548 |
T17930 |
T17931 |
arg1Of |
Graphics,"," |
R12549 |
T17931 |
T17933 |
arg1Of |
",","," |
R1255 |
T2138 |
T2132 |
arg1Of |
shown,Specifically |
R12550 |
T17932 |
T17931 |
arg2Of |
Asheville,"," |
R12551 |
T17933 |
T17936 |
arg1Of |
",","," |
R12552 |
T17935 |
T17933 |
arg2Of |
Carolina,"," |
R12553 |
T17935 |
T17934 |
arg1Of |
Carolina,North |
R12554 |
T17936 |
T17928 |
arg2Of |
",",( |
R12555 |
T17938 |
T17936 |
arg2Of |
States,"," |
R12556 |
T17938 |
T17937 |
arg1Of |
States,United |
R12557 |
T17939 |
T17928 |
arg3Of |
),( |
R12558 |
T17942 |
T17941 |
arg1Of |
images,Original |
R12559 |
T17942 |
T17943 |
arg1Of |
images,are |
R1256 |
T2138 |
T2133 |
arg1Of |
shown,"," |
R12560 |
T17942 |
T17944 |
arg1Of |
images,available |
R12561 |
T17944 |
T17943 |
arg2Of |
available,are |
R1257 |
T2138 |
T2136 |
arg2Of |
shown,have |
R1258 |
T2138 |
T2137 |
arg2Of |
shown,been |
R1259 |
T2140 |
T2138 |
arg3Of |
modulate,shown |
R126 |
T335 |
T332 |
arg2Of |
cells,of |
R1260 |
T2140 |
T2139 |
arg1Of |
modulate,to |
R1261 |
T2142 |
T2140 |
arg2Of |
genes,modulate |
R1262 |
T2142 |
T2141 |
arg1Of |
genes,β-globin |
R1263 |
T2142 |
T2143 |
arg1Of |
genes,[ |
R1264 |
T2144 |
T2143 |
arg2Of |
18–21,[ |
R1265 |
T2145 |
T2143 |
arg3Of |
],[ |
R1266 |
T2149 |
T2146 |
arg1Of |
genes,The |
R1267 |
T2149 |
T2147 |
arg1Of |
genes,mouse |
R1268 |
T2149 |
T2148 |
arg1Of |
genes,β-globin |
R1269 |
T2149 |
T2150 |
arg1Of |
genes,{ |
R127 |
T335 |
T333 |
arg1Of |
cells,nucleated |
R1270 |
T2149 |
T2160 |
arg1Of |
genes,are |
R1271 |
T2149 |
T2161 |
arg2Of |
genes,clustered |
R1272 |
T2151 |
T2152 |
arg1Of |
ɛy,"," |
R1273 |
T2151 |
T2154 |
arg1Of |
ɛy,"," |
R1274 |
T2153 |
T2152 |
arg2Of |
βh1,"," |
R1275 |
T2154 |
T2150 |
arg2Of |
",",{ |
R12754 |
T18187 |
T18186 |
arg1Of |
embryos,18.5-dpc |
R12755 |
T18187 |
T18188 |
arg1Of |
embryos,were |
R12756 |
T18187 |
T18189 |
arg2Of |
embryos,exsanguinated |
R12757 |
T18189 |
T18188 |
arg2Of |
exsanguinated,were |
R12758 |
T18189 |
T18190 |
arg1Of |
exsanguinated,and |
R12759 |
T18193 |
T18191 |
arg1Of |
smears,peripheral |
R1276 |
T2155 |
T2157 |
arg1Of |
β-major,and |
R12760 |
T18193 |
T18192 |
arg1Of |
smears,blood |
R12761 |
T18193 |
T18194 |
arg1Of |
smears,were |
R12762 |
T18193 |
T18195 |
arg2Of |
smears,prepared |
R12763 |
T18195 |
T18190 |
arg2Of |
prepared,and |
R12764 |
T18195 |
T18194 |
arg2Of |
prepared,were |
R12765 |
T18195 |
T18196 |
arg1Of |
prepared,from |
R12766 |
T18198 |
T18199 |
arg1Of |
mutant,and |
R12767 |
T18199 |
T18197 |
arg1Of |
and,both |
R12768 |
T18200 |
T18199 |
arg2Of |
WT,and |
R12769 |
T18201 |
T18196 |
arg2Of |
mice,from |
R1277 |
T2157 |
T2154 |
arg2Of |
and,"," |
R12770 |
T18201 |
T18198 |
arg1Of |
mice,mutant |
R12771 |
T18201 |
T18200 |
arg1Of |
mice,WT |
R12772 |
T18203 |
T18202 |
arg1Of |
slides,The |
R12773 |
T18203 |
T18204 |
arg1Of |
slides,were |
R12774 |
T18203 |
T18205 |
arg2Of |
slides,Wright-stained |
R12775 |
T18203 |
T18207 |
arg2Of |
slides,read |
R12776 |
T18205 |
T18206 |
arg1Of |
Wright-stained,and |
R12777 |
T18206 |
T18204 |
arg2Of |
and,were |
R12778 |
T18207 |
T18206 |
arg2Of |
read,and |
R12779 |
T18209 |
T18207 |
arg1Of |
DAF,read |
R1278 |
T2157 |
T2156 |
arg1Of |
and,"," |
R12780 |
T18209 |
T18208 |
arg2Of |
DAF,by |
R12781 |
T18213 |
T18210 |
arg2Of |
analysis,For |
R12782 |
T18213 |
T18211 |
arg1Of |
analysis,whole |
R12783 |
T18213 |
T18212 |
arg1Of |
analysis,mount |
R12784 |
T18215 |
T18216 |
arg1Of |
14.5-dpc,WT |
R12785 |
T18215 |
T18217 |
arg1Of |
14.5-dpc,and |
R12786 |
T18218 |
T18217 |
arg2Of |
mutant,and |
R12787 |
T18219 |
T18215 |
arg1Of |
embryos,14.5-dpc |
R12788 |
T18219 |
T18218 |
arg1Of |
embryos,mutant |
R12789 |
T18219 |
T18221 |
arg1Of |
embryos,and |
R1279 |
T2158 |
T2157 |
arg2Of |
β-minor,and |
R12790 |
T18221 |
T18220 |
arg1Of |
and,"," |
R12791 |
T18221 |
T18225 |
arg1Of |
and,were |
R12792 |
T18221 |
T18226 |
arg2Of |
and,fixed |
R12793 |
T18221 |
T18240 |
arg2Of |
and,stained |
R12794 |
T18224 |
T18221 |
arg2Of |
mice,and |
R12795 |
T18224 |
T18222 |
arg1Of |
mice,postnatal |
R12796 |
T18224 |
T18223 |
arg1Of |
mice,day–10.5 |
R12797 |
T18226 |
T18227 |
arg1Of |
fixed,in |
R12798 |
T18226 |
T18239 |
arg1Of |
fixed,and |
R12799 |
T18228 |
T18229 |
arg1Of |
10,% |
R128 |
T335 |
T334 |
arg1Of |
cells,red |
R1280 |
T2159 |
T2150 |
arg3Of |
},{ |
R12800 |
T18230 |
T18227 |
arg2Of |
formalin,in |
R12801 |
T18230 |
T18228 |
arg1Of |
formalin,10 |
R12802 |
T18230 |
T18231 |
arg1Of |
formalin,"," |
R12803 |
T18230 |
T18233 |
arg1Of |
formalin,"," |
R12804 |
T18230 |
T18234 |
arg2Of |
formalin,sectioned |
R12805 |
T18232 |
T18231 |
arg2Of |
paraffin-embedded,"," |
R12806 |
T18234 |
T18235 |
arg1Of |
sectioned,at |
R12807 |
T18237 |
T18235 |
arg2Of |
μm,at |
R12808 |
T18237 |
T18236 |
arg1Of |
μm,5 |
R12809 |
T18239 |
T18210 |
arg1Of |
and,For |
R1281 |
T2161 |
T2160 |
arg2Of |
clustered,are |
R12810 |
T18239 |
T18214 |
arg1Of |
and,"," |
R12811 |
T18239 |
T18225 |
arg2Of |
and,were |
R12812 |
T18239 |
T18238 |
arg1Of |
and,"," |
R12813 |
T18240 |
T18239 |
arg2Of |
stained,and |
R12814 |
T18240 |
T18241 |
arg1Of |
stained,with |
R12815 |
T18242 |
T18243 |
arg1Of |
hematoxylin,and |
R12816 |
T18243 |
T18241 |
arg2Of |
and,with |
R12817 |
T18244 |
T18243 |
arg2Of |
eosin,and |
R12818 |
T18246 |
T18245 |
arg1Of |
samples,Liver |
R12819 |
T18246 |
T18247 |
arg1Of |
samples,( |
R1282 |
T2161 |
T2162 |
arg1Of |
clustered,on |
R12820 |
T18246 |
T18255 |
arg1Of |
samples,were |
R12821 |
T18246 |
T18256 |
arg2Of |
samples,prepared |
R12822 |
T18248 |
T18247 |
arg2Of |
at,( |
R12823 |
T18250 |
T18249 |
arg1Of |
dpc,14.5 |
R12824 |
T18250 |
T18251 |
arg1Of |
dpc,and |
R12825 |
T18251 |
T18248 |
arg2Of |
and,at |
R12826 |
T18253 |
T18251 |
arg2Of |
dpc,and |
R12827 |
T18253 |
T18252 |
arg1Of |
dpc,18.5 |
R12828 |
T18254 |
T18247 |
arg3Of |
),( |
R12829 |
T18256 |
T18255 |
arg2Of |
prepared,were |
R1283 |
T2161 |
T2165 |
arg1Of |
clustered,and |
R12830 |
T18256 |
T18257 |
arg1Of |
prepared,in |
R12831 |
T18260 |
T18257 |
arg2Of |
manner,in |
R12832 |
T18260 |
T18258 |
arg1Of |
manner,a |
R12833 |
T18260 |
T18259 |
arg1Of |
manner,similar |
R12834 |
T18261 |
T18262 |
arg1Of |
Images,were |
R12835 |
T18261 |
T18263 |
arg2Of |
Images,obtained |
R12836 |
T18263 |
T18262 |
arg2Of |
obtained,were |
R12837 |
T18263 |
T18264 |
arg1Of |
obtained,with |
R12838 |
T18267 |
T18264 |
arg2Of |
microscope,with |
R12839 |
T18267 |
T18265 |
arg1Of |
microscope,Nikon |
R1284 |
T2163 |
T2162 |
arg2Of |
Chromosome,on |
R12840 |
T18267 |
T18266 |
arg1Of |
microscope,Labophot-2 |
R12841 |
T18268 |
T18269 |
arg2Of |
Objectives,used |
R12842 |
T18268 |
T18270 |
arg1Of |
Objectives,were |
R12843 |
T18274 |
T18273 |
arg1Of |
160/0.17,40/0.65 |
R12844 |
T18275 |
T18270 |
arg2Of |
Nikon,were |
R12845 |
T18275 |
T18271 |
arg1Of |
Nikon,E |
R12846 |
T18275 |
T18272 |
arg1Of |
Nikon,Plan |
R12847 |
T18275 |
T18274 |
arg1Of |
Nikon,160/0.17 |
R12848 |
T18275 |
T18276 |
arg1Of |
Nikon,( |
R12849 |
T18275 |
T18280 |
arg1Of |
Nikon,"," |
R1285 |
T2163 |
T2164 |
arg1Of |
Chromosome,7 |
R12850 |
T18278 |
T18276 |
arg2Of |
objective,( |
R12851 |
T18278 |
T18277 |
arg1Of |
objective,40× |
R12852 |
T18279 |
T18276 |
arg3Of |
),( |
R12853 |
T18282 |
T18283 |
arg1Of |
Plan,100/1.25 |
R12854 |
T18286 |
T18280 |
arg2Of |
Nikon,"," |
R12855 |
T18286 |
T18281 |
arg1Of |
Nikon,E |
R12856 |
T18286 |
T18282 |
arg1Of |
Nikon,Plan |
R12857 |
T18286 |
T18284 |
arg1Of |
Nikon,oil |
R12858 |
T18286 |
T18285 |
arg1Of |
Nikon,160/0.17 |
R12859 |
T18286 |
T18287 |
arg1Of |
Nikon,( |
R1286 |
T2166 |
T2167 |
arg1Of |
they,are |
R12860 |
T18289 |
T18287 |
arg2Of |
objective,( |
R12861 |
T18289 |
T18288 |
arg1Of |
objective,100× |
R12862 |
T18290 |
T18287 |
arg3Of |
),( |
R12863 |
T18292 |
T18291 |
arg1Of |
camera,The |
R12864 |
T18292 |
T18293 |
arg1Of |
camera,was |
R12865 |
T18296 |
T18293 |
arg2Of |
Coolpix,was |
R12866 |
T18296 |
T18294 |
arg1Of |
Coolpix,a |
R12867 |
T18296 |
T18295 |
arg1Of |
Coolpix,Nikon |
R12868 |
T18296 |
T18297 |
arg1Of |
Coolpix,4300 |
R12869 |
T18299 |
T18298 |
arg1Of |
images,Original |
R1287 |
T2166 |
T2169 |
arg1Of |
they,homologous |
R12870 |
T18299 |
T18300 |
arg1Of |
images,are |
R12871 |
T18299 |
T18301 |
arg1Of |
images,available |
R12872 |
T18301 |
T18300 |
arg2Of |
available,are |
R1288 |
T2167 |
T2165 |
arg2Of |
are,and |
R1289 |
T2167 |
T2174 |
arg1Of |
are,in |
R129 |
T336 |
T329 |
arg2Of |
are,and |
R1290 |
T2167 |
T2179 |
arg1Of |
are,[ |
R1291 |
T2169 |
T2167 |
arg2Of |
homologous,are |
R1292 |
T2169 |
T2168 |
arg1Of |
homologous,highly |
R1293 |
T2169 |
T2170 |
arg1Of |
homologous,to |
R1294 |
T2173 |
T2170 |
arg2Of |
counterparts,to |
R1295 |
T2173 |
T2171 |
arg1Of |
counterparts,their |
R1296 |
T2173 |
T2172 |
arg1Of |
counterparts,human |
R1297 |
T2176 |
T2177 |
arg1Of |
structure,and |
R1298 |
T2177 |
T2174 |
arg2Of |
and,in |
R1299 |
T2177 |
T2175 |
arg1Of |
and,organizational |
R130 |
T337 |
T336 |
arg2Of |
present,are |
R1300 |
T2178 |
T2177 |
arg2Of |
function,and |
R13006 |
T18462 |
T18461 |
arg1Of |
blot,Northern |
R13007 |
T18469 |
T18463 |
arg1Of |
filter,A |
R13008 |
T18469 |
T18464 |
arg1Of |
filter,mouse |
R13009 |
T18469 |
T18465 |
arg1Of |
filter,embryonic |
R1301 |
T2180 |
T2179 |
arg2Of |
22,[ |
R13010 |
T18469 |
T18466 |
arg1Of |
filter,tissue |
R13011 |
T18469 |
T18467 |
arg1Of |
filter,Northern |
R13012 |
T18469 |
T18468 |
arg1Of |
filter,blot |
R13013 |
T18469 |
T18470 |
arg1Of |
filter,( |
R13014 |
T18469 |
T18480 |
arg1Of |
filter,was |
R13015 |
T18469 |
T18481 |
arg2Of |
filter,hybridized |
R13016 |
T18471 |
T18470 |
arg2Of |
Seegene,( |
R13017 |
T18471 |
T18472 |
arg1Of |
Seegene,"," |
R13018 |
T18471 |
T18476 |
arg1Of |
Seegene,"," |
R13019 |
T18473 |
T18474 |
arg1Of |
Rockville,"," |
R1302 |
T2181 |
T2179 |
arg3Of |
],[ |
R13020 |
T18474 |
T18472 |
arg2Of |
",","," |
R13021 |
T18475 |
T18474 |
arg2Of |
Maryland,"," |
R13022 |
T18478 |
T18476 |
arg2Of |
States,"," |
R13023 |
T18478 |
T18477 |
arg1Of |
States,United |
R13024 |
T18479 |
T18470 |
arg3Of |
),( |
R13025 |
T18481 |
T18480 |
arg2Of |
hybridized,was |
R13026 |
T18481 |
T18482 |
arg1Of |
hybridized,with |
R13027 |
T18481 |
T18500 |
arg1Of |
hybridized,"," |
R13028 |
T18481 |
T18501 |
arg1Of |
hybridized,by |
R13029 |
T18485 |
T18482 |
arg2Of |
probe,with |
R1303 |
T2183 |
T2182 |
arg1Of |
expression,High-level |
R13030 |
T18485 |
T18483 |
arg1Of |
probe,a |
R13031 |
T18485 |
T18484 |
arg1Of |
probe,Sox6 |
R13032 |
T18485 |
T18486 |
arg2Of |
probe,generated |
R13033 |
T18485 |
T18494 |
arg2Of |
probe,labeled |
R13034 |
T18486 |
T18487 |
arg1Of |
generated,by |
R13035 |
T18486 |
T18493 |
arg1Of |
generated,and |
R13036 |
T18488 |
T18487 |
arg2Of |
RT-PCR,by |
R13037 |
T18488 |
T18489 |
arg1Of |
RT-PCR,( |
R13038 |
T18490 |
T18489 |
arg2Of |
nucleotides,( |
R13039 |
T18490 |
T18491 |
arg1Of |
nucleotides,1353–1927 |
R1304 |
T2183 |
T2184 |
arg1Of |
expression,of |
R13040 |
T18492 |
T18489 |
arg3Of |
),( |
R13041 |
T18494 |
T18493 |
arg2Of |
labeled,and |
R13042 |
T18494 |
T18495 |
arg1Of |
labeled,with |
R13043 |
T18497 |
T18496 |
arg2Of |
α-32P,[ |
R13044 |
T18498 |
T18496 |
arg3Of |
],[ |
R13045 |
T18499 |
T18495 |
arg2Of |
dCTP,with |
R13046 |
T18499 |
T18496 |
arg1Of |
dCTP,[ |
R13047 |
T18504 |
T18501 |
arg2Of |
labeling,by |
R13048 |
T18504 |
T18502 |
arg1Of |
labeling,random |
R13049 |
T18504 |
T18503 |
arg1Of |
labeling,primer |
R1305 |
T2183 |
T2187 |
arg1Of |
expression,requires |
R13050 |
T18504 |
T18505 |
arg1Of |
labeling,( |
R13051 |
T18506 |
T18507 |
arg1Of |
RediprimeII,; |
R13052 |
T18507 |
T18505 |
arg2Of |
;,( |
R13053 |
T18507 |
T18514 |
arg1Of |
;,"," |
R13054 |
T18509 |
T18508 |
arg1Of |
Biosciences,Amersham |
R13055 |
T18509 |
T18510 |
arg1Of |
Biosciences,"," |
R13056 |
T18510 |
T18512 |
arg1Of |
",","," |
R13057 |
T18511 |
T18510 |
arg2Of |
Buckinghamshire,"," |
R13058 |
T18512 |
T18507 |
arg2Of |
",",; |
R13059 |
T18513 |
T18512 |
arg2Of |
England,"," |
R1306 |
T2186 |
T2184 |
arg2Of |
genes,of |
R13060 |
T18516 |
T18514 |
arg2Of |
Kingdom,"," |
R13061 |
T18516 |
T18515 |
arg1Of |
Kingdom,United |
R13062 |
T18517 |
T18505 |
arg3Of |
),( |
R13063 |
T18519 |
T18518 |
arg1Of |
hybridization,The |
R13064 |
T18519 |
T18520 |
arg1Of |
hybridization,was |
R13065 |
T18519 |
T18521 |
arg2Of |
hybridization,performed |
R13066 |
T18521 |
T18520 |
arg2Of |
performed,was |
R13067 |
T18521 |
T18522 |
arg1Of |
performed,in |
R13068 |
T18523 |
T18522 |
arg2Of |
phosphate,in |
R13069 |
T18523 |
T18524 |
arg2Of |
phosphate,buffered |
R1307 |
T2186 |
T2185 |
arg1Of |
genes,these |
R13070 |
T18525 |
T18526 |
arg1Of |
7,% |
R13071 |
T18529 |
T18524 |
arg3Of |
solution,buffered |
R13072 |
T18529 |
T18525 |
arg1Of |
solution,7 |
R13073 |
T18529 |
T18527 |
arg1Of |
solution,SDS |
R13074 |
T18529 |
T18528 |
arg1Of |
solution,hybridization |
R13075 |
T18530 |
T18531 |
arg1Of |
Blots,were |
R13076 |
T18530 |
T18532 |
arg2Of |
Blots,washed |
R13077 |
T18532 |
T18531 |
arg2Of |
washed,were |
R13078 |
T18532 |
T18533 |
arg1Of |
washed,with |
R13079 |
T18535 |
T18536 |
arg1Of |
SSC,"," |
R1308 |
T2190 |
T2187 |
arg2Of |
element,requires |
R13080 |
T18536 |
T18534 |
arg1Of |
",",0.2× |
R13081 |
T18538 |
T18536 |
arg2Of |
%,"," |
R13082 |
T18538 |
T18537 |
arg1Of |
%,1 |
R13083 |
T18539 |
T18533 |
arg2Of |
SDS,with |
R13084 |
T18539 |
T18535 |
arg1Of |
SDS,SSC |
R13085 |
T18539 |
T18538 |
arg1Of |
SDS,% |
R13086 |
T18539 |
T18540 |
arg1Of |
SDS,at |
R13087 |
T18539 |
T18543 |
arg1Of |
SDS,prior |
R13088 |
T18539 |
T18549 |
arg1Of |
SDS,( |
R13089 |
T18539 |
T18560 |
arg1Of |
SDS,at |
R1309 |
T2190 |
T2188 |
arg1Of |
element,a |
R13090 |
T18542 |
T18540 |
arg2Of |
°C,at |
R13091 |
T18542 |
T18541 |
arg1Of |
°C,60 |
R13092 |
T18543 |
T18544 |
arg1Of |
prior,to |
R13093 |
T18545 |
T18544 |
arg2Of |
exposure,to |
R13094 |
T18545 |
T18546 |
arg1Of |
exposure,to |
R13095 |
T18548 |
T18546 |
arg2Of |
film,to |
R13096 |
T18548 |
T18547 |
arg1Of |
film,X-ray |
R13097 |
T18550 |
T18551 |
arg1Of |
Kodak,"," |
R13098 |
T18551 |
T18553 |
arg1Of |
",","," |
R13099 |
T18552 |
T18551 |
arg2Of |
Rochester,"," |
R131 |
T337 |
T338 |
arg1Of |
present,in |
R1310 |
T2190 |
T2189 |
arg1Of |
element,regulatory |
R13100 |
T18553 |
T18556 |
arg1Of |
",","," |
R13101 |
T18555 |
T18553 |
arg2Of |
York,"," |
R13102 |
T18555 |
T18554 |
arg1Of |
York,New |
R13103 |
T18556 |
T18549 |
arg2Of |
",",( |
R13104 |
T18558 |
T18556 |
arg2Of |
States,"," |
R13105 |
T18558 |
T18557 |
arg1Of |
States,United |
R13106 |
T18559 |
T18549 |
arg3Of |
),( |
R13107 |
T18562 |
T18560 |
arg2Of |
°C,at |
R13108 |
T18562 |
T18561 |
arg1Of |
°C,−80 |
R13109 |
T18562 |
T18563 |
arg1Of |
°C,for |
R1311 |
T2190 |
T2191 |
arg1Of |
element,"," |
R13110 |
T18565 |
T18563 |
arg2Of |
d,for |
R13111 |
T18565 |
T18564 |
arg1Of |
d,6 |
R1312 |
T2270 |
T2268 |
arg1Of |
cells,definitive |
R1313 |
T2270 |
T2269 |
arg1Of |
cells,erythroid |
R1314 |
T2270 |
T2271 |
arg1Of |
cells,express |
R1315 |
T2195 |
T2191 |
arg2Of |
region,"," |
R1316 |
T2271 |
T2267 |
arg2Of |
express,where |
R1317 |
T2274 |
T2271 |
arg2Of |
globins,express |
R1318 |
T2274 |
T2272 |
arg1Of |
globins,adult |
R1319 |
T2274 |
T2273 |
arg1Of |
globins,β |
R132 |
T341 |
T338 |
arg2Of |
circulation,in |
R1320 |
T2276 |
T2252 |
arg1Of |
β,At |
R1321 |
T2276 |
T2260 |
arg1Of |
β,"," |
R1322 |
T2276 |
T2275 |
arg1Of |
β,( |
R13227 |
T18724 |
T18725 |
arg1Of |
culture,and |
R13228 |
T18725 |
T18723 |
arg1Of |
and,Cell |
R13229 |
T18726 |
T18725 |
arg2Of |
transfection,and |
R1323 |
T2277 |
T2278 |
arg1Of |
major,and |
R13230 |
T18728 |
T18727 |
arg1Of |
cells,GM979 |
R13231 |
T18728 |
T18729 |
arg1Of |
cells,( |
R13232 |
T18728 |
T18742 |
arg1Of |
cells,were |
R13233 |
T18728 |
T18743 |
arg2Of |
cells,cultured |
R13234 |
T18732 |
T18730 |
arg1Of |
Repositories,Coriell |
R13235 |
T18732 |
T18731 |
arg1Of |
Repositories,Cell |
R13236 |
T18732 |
T18733 |
arg1Of |
Repositories,"," |
R13237 |
T18733 |
T18735 |
arg1Of |
",","," |
R13238 |
T18734 |
T18733 |
arg2Of |
Camden,"," |
R13239 |
T18736 |
T18735 |
arg2Of |
New,"," |
R1324 |
T2195 |
T2192 |
arg1Of |
region,the |
R13240 |
T18737 |
T18729 |
arg2Of |
Jersey,( |
R13241 |
T18737 |
T18732 |
arg1Of |
Jersey,Repositories |
R13242 |
T18737 |
T18734 |
arg1Of |
Jersey,Camden |
R13243 |
T18737 |
T18736 |
arg1Of |
Jersey,New |
R13244 |
T18737 |
T18738 |
arg1Of |
Jersey,"," |
R13245 |
T18740 |
T18738 |
arg2Of |
States,"," |
R13246 |
T18740 |
T18739 |
arg1Of |
States,United |
R13247 |
T18741 |
T18729 |
arg3Of |
),( |
R13248 |
T18743 |
T18742 |
arg2Of |
cultured,were |
R13249 |
T18743 |
T18744 |
arg1Of |
cultured,in |
R1325 |
T2195 |
T2193 |
arg1Of |
region,locus |
R13250 |
T18745 |
T18746 |
arg2Of |
Ham,'s |
R13251 |
T18747 |
T18744 |
arg2Of |
F12,in |
R13252 |
T18747 |
T18746 |
arg1Of |
F12,'s |
R13253 |
T18747 |
T18748 |
arg1Of |
F12,with |
R13254 |
T18749 |
T18750 |
arg1Of |
2,mM |
R13255 |
T18751 |
T18748 |
arg2Of |
L-glutamine,with |
R13256 |
T18751 |
T18749 |
arg1Of |
L-glutamine,2 |
R13257 |
T18751 |
T18752 |
arg2Of |
L-glutamine,supplemented |
R13258 |
T18752 |
T18753 |
arg1Of |
supplemented,with |
R13259 |
T18755 |
T18756 |
arg1Of |
10,% |
R1326 |
T2279 |
T2278 |
arg2Of |
minor,and |
R13260 |
T18759 |
T18754 |
arg1Of |
serum,heat-inactivated |
R13261 |
T18759 |
T18755 |
arg1Of |
serum,10 |
R13262 |
T18759 |
T18757 |
arg1Of |
serum,fetal |
R13263 |
T18759 |
T18758 |
arg1Of |
serum,calf |
R13264 |
T18759 |
T18760 |
arg1Of |
serum,( |
R13265 |
T18759 |
T18782 |
arg1Of |
serum,and |
R13266 |
T18761 |
T18762 |
arg1Of |
Ivitrogen,"," |
R13267 |
T18762 |
T18764 |
arg1Of |
",","," |
R13268 |
T18763 |
T18762 |
arg2Of |
Carlsbad,"," |
R13269 |
T18764 |
T18766 |
arg1Of |
",","," |
R1327 |
T2195 |
T2194 |
arg1Of |
region,control |
R13270 |
T18765 |
T18764 |
arg2Of |
California,"," |
R13271 |
T18766 |
T18769 |
arg1Of |
",",) |
R13272 |
T18766 |
T18770 |
arg1Of |
",","," |
R13273 |
T18768 |
T18766 |
arg2Of |
States,"," |
R13274 |
T18768 |
T18767 |
arg1Of |
States,United |
R13275 |
T18770 |
T18776 |
arg1Of |
",","," |
R13276 |
T18771 |
T18770 |
arg2Of |
penicillin,"," |
R13277 |
T18771 |
T18772 |
arg1Of |
penicillin,( |
R13278 |
T18774 |
T18772 |
arg2Of |
units/ml,( |
R13279 |
T18774 |
T18773 |
arg1Of |
units/ml,100 |
R1328 |
T2195 |
T2196 |
arg1Of |
region,that |
R13280 |
T18775 |
T18772 |
arg3Of |
),( |
R13281 |
T18776 |
T18760 |
arg2Of |
",",( |
R13282 |
T18779 |
T18776 |
arg2Of |
μg/ml,"," |
R13283 |
T18779 |
T18777 |
arg1Of |
μg/ml,streptomycin |
R13284 |
T18779 |
T18778 |
arg1Of |
μg/ml,100 |
R13285 |
T18780 |
T18760 |
arg3Of |
),( |
R13286 |
T18782 |
T18753 |
arg2Of |
and,with |
R13287 |
T18782 |
T18781 |
arg1Of |
and,"," |
R13288 |
T18783 |
T18782 |
arg2Of |
L-glutamine,and |
R13289 |
T18783 |
T18784 |
arg1Of |
L-glutamine,( |
R1329 |
T2195 |
T2197 |
arg1Of |
region,is |
R13290 |
T18786 |
T18784 |
arg2Of |
mM,( |
R13291 |
T18786 |
T18785 |
arg1Of |
mM,2 |
R13292 |
T18787 |
T18784 |
arg3Of |
),( |
R13293 |
T18789 |
T18788 |
arg1Of |
cells,MEL |
R13294 |
T18789 |
T18790 |
arg1Of |
cells,were |
R13295 |
T18789 |
T18791 |
arg2Of |
cells,cultured |
R13296 |
T18791 |
T18790 |
arg2Of |
cultured,were |
R13297 |
T18791 |
T18792 |
arg1Of |
cultured,in |
R13298 |
T18793 |
T18792 |
arg2Of |
DMEM,in |
R13299 |
T18793 |
T18794 |
arg2Of |
DMEM,supplemented |
R133 |
T341 |
T339 |
arg1Of |
circulation,the |
R1330 |
T2282 |
T2276 |
arg2Of |
22,β |
R13300 |
T18794 |
T18795 |
arg1Of |
supplemented,as |
R13301 |
T18794 |
T18797 |
arg1Of |
supplemented,( |
R13302 |
T18796 |
T18795 |
arg2Of |
above,as |
R13303 |
T18798 |
T18797 |
arg2Of |
without,( |
R13304 |
T18799 |
T18798 |
arg2Of |
heat,without |
R13305 |
T18799 |
T18800 |
arg1Of |
heat,inactivating |
R13306 |
T18802 |
T18800 |
arg2Of |
serum,inactivating |
R13307 |
T18802 |
T18801 |
arg1Of |
serum,the |
R13308 |
T18803 |
T18797 |
arg3Of |
),( |
R13309 |
T18805 |
T18804 |
arg1Of |
cells,GM979 |
R1331 |
T2282 |
T2277 |
arg1Of |
22,major |
R13310 |
T18805 |
T18806 |
arg1Of |
cells,( |
R13311 |
T18805 |
T18811 |
arg1Of |
cells,in |
R13312 |
T18805 |
T18816 |
arg1Of |
cells,were |
R13313 |
T18805 |
T18817 |
arg2Of |
cells,transfected |
R13314 |
T18808 |
T18806 |
arg2Of |
×,( |
R13315 |
T18808 |
T18807 |
arg1Of |
×,4 |
R13316 |
T18808 |
T18809 |
arg1Of |
×,105 |
R13317 |
T18810 |
T18806 |
arg3Of |
),( |
R13318 |
T18813 |
T18811 |
arg2Of |
phase,in |
R13319 |
T18813 |
T18812 |
arg1Of |
phase,log |
R1332 |
T2282 |
T2279 |
arg1Of |
22,minor |
R13320 |
T18813 |
T18814 |
arg1Of |
phase,of |
R13321 |
T18815 |
T18814 |
arg2Of |
growth,of |
R13322 |
T18817 |
T18816 |
arg2Of |
transfected,were |
R13323 |
T18817 |
T18818 |
arg1Of |
transfected,with |
R13324 |
T18817 |
T18820 |
arg1Of |
transfected,by |
R13325 |
T18817 |
T18822 |
arg1Of |
transfected,( |
R13326 |
T18819 |
T18818 |
arg2Of |
plasmids,with |
R13327 |
T18821 |
T18820 |
arg2Of |
FuGENE6,by |
R13328 |
T18823 |
T18824 |
arg1Of |
Roche,"," |
R13329 |
T18824 |
T18826 |
arg1Of |
",","," |
R1333 |
T2282 |
T2280 |
arg1Of |
22,) |
R13330 |
T18825 |
T18824 |
arg2Of |
Indianapolis,"," |
R13331 |
T18826 |
T18828 |
arg1Of |
",","," |
R13332 |
T18827 |
T18826 |
arg2Of |
Indiana,"," |
R13333 |
T18829 |
T18828 |
arg2Of |
United,"," |
R13334 |
T18830 |
T18822 |
arg2Of |
States,( |
R13335 |
T18830 |
T18823 |
arg1Of |
States,Roche |
R13336 |
T18830 |
T18825 |
arg1Of |
States,Indianapolis |
R13337 |
T18830 |
T18827 |
arg1Of |
States,Indiana |
R13338 |
T18830 |
T18829 |
arg1Of |
States,United |
R13339 |
T18831 |
T18822 |
arg3Of |
),( |
R1334 |
T2282 |
T2281 |
arg2Of |
22,[ |
R13340 |
T18832 |
T18833 |
arg1Of |
Cells,were |
R13341 |
T18832 |
T18834 |
arg2Of |
Cells,transfected |
R13342 |
T18834 |
T18833 |
arg2Of |
transfected,were |
R13343 |
T18834 |
T18835 |
arg1Of |
transfected,with |
R13344 |
T18834 |
T18844 |
arg1Of |
transfected,along |
R13345 |
T18839 |
T18835 |
arg2Of |
constructs,with |
R13346 |
T18839 |
T18836 |
arg1Of |
constructs,ɛy |
R13347 |
T18839 |
T18837 |
arg1Of |
constructs,promoter |
R13348 |
T18839 |
T18838 |
arg1Of |
constructs,reporter |
R13349 |
T18839 |
T18840 |
arg1Of |
constructs,( |
R1335 |
T2283 |
T2281 |
arg3Of |
],[ |
R13350 |
T18842 |
T18840 |
arg2Of |
ng,( |
R13351 |
T18842 |
T18841 |
arg1Of |
ng,500 |
R13352 |
T18843 |
T18840 |
arg3Of |
),( |
R13353 |
T18844 |
T18845 |
arg1Of |
along,with |
R13354 |
T18848 |
T18847 |
arg1Of |
vector,empty |
R13355 |
T18848 |
T18849 |
arg1Of |
vector,or |
R13356 |
T18849 |
T18845 |
arg2Of |
or,with |
R13357 |
T18849 |
T18846 |
arg1Of |
or,either |
R13358 |
T18852 |
T18849 |
arg2Of |
vector,or |
R13359 |
T18852 |
T18850 |
arg1Of |
vector,Sox6 |
R1336 |
T2195 |
T2198 |
arg2Of |
region,characterized |
R13360 |
T18852 |
T18851 |
arg1Of |
vector,overexpression |
R13361 |
T18852 |
T18853 |
arg1Of |
vector,( |
R13362 |
T18855 |
T18853 |
arg2Of |
ng,( |
R13363 |
T18855 |
T18854 |
arg1Of |
ng,1000 |
R13364 |
T18856 |
T18853 |
arg3Of |
),( |
R13365 |
T18858 |
T18857 |
arg2Of |
assays,In |
R13366 |
T18858 |
T18859 |
arg1Of |
assays,of |
R13367 |
T18861 |
T18859 |
arg2Of |
effect,of |
R13368 |
T18861 |
T18860 |
arg1Of |
effect,dosage |
R13369 |
T18863 |
T18864 |
arg1Of |
we,used |
R1337 |
T2198 |
T2197 |
arg2Of |
characterized,is |
R13370 |
T18864 |
T18857 |
arg1Of |
used,In |
R13371 |
T18864 |
T18862 |
arg1Of |
used,"," |
R13372 |
T18866 |
T18865 |
arg1Of |
ng,200 |
R13373 |
T18866 |
T18867 |
arg1Of |
ng,"," |
R13374 |
T18867 |
T18871 |
arg1Of |
",",and |
R13375 |
T18869 |
T18867 |
arg2Of |
ng,"," |
R13376 |
T18869 |
T18868 |
arg1Of |
ng,500 |
R13377 |
T18871 |
T18864 |
arg2Of |
and,used |
R13378 |
T18871 |
T18870 |
arg1Of |
and,"," |
R13379 |
T18871 |
T18874 |
arg1Of |
and,) |
R1338 |
T2286 |
T2284 |
arg1Of |
gene,The |
R13380 |
T18871 |
T18880 |
modOf |
and,ega |
R13381 |
T18873 |
T18871 |
arg2Of |
ng,and |
R13382 |
T18873 |
T18872 |
arg1Of |
ng,1000 |
R13383 |
T18876 |
T18875 |
arg1Of |
MV 1,. pRL-C |
R13384 |
T18876 |
T18877 |
arg1Of |
MV 1,5 |
R13385 |
T18876 |
T18880 |
arg1Of |
MV 1,ega |
R13386 |
T18876 |
T18881 |
arg2Of |
MV 1,) wa |
R13387 |
T18878 |
T18877 |
arg2Of |
ng (Pro,5 |
R13388 |
T18879 |
T18877 |
arg3Of |
m,5 |
R13389 |
T18881 |
T18880 |
arg2Of |
) wa,ega |
R1339 |
T2286 |
T2285 |
arg1Of |
gene,ɛy |
R13390 |
T18881 |
T18882 |
arg1Of |
) wa,s |
R13391 |
T18884 |
T18882 |
arg2Of |
sed as ,s |
R13392 |
T18884 |
T18883 |
arg1Of |
sed as ,u |
R13393 |
T18884 |
T18885 |
arg1Of |
sed as ,a c |
R13394 |
T18887 |
T18885 |
arg2Of |
ransfectio,a c |
R13395 |
T18887 |
T18886 |
arg1Of |
ransfectio,ontrol for t |
R134 |
T341 |
T340 |
arg1Of |
circulation,fetal |
R1340 |
T2286 |
T2287 |
arg1Of |
gene,is |
R1341 |
T2286 |
T2288 |
arg2Of |
gene,silenced |
R1342 |
T2288 |
T2287 |
arg2Of |
silenced,is |
R1343 |
T2288 |
T2289 |
arg1Of |
silenced,in |
R1344 |
T2201 |
T2198 |
arg1Of |
set,characterized |
R1345 |
T2292 |
T2289 |
arg2Of |
cells,in |
R1346 |
T2292 |
T2290 |
arg1Of |
cells,definitive |
R1347 |
T2292 |
T2291 |
arg1Of |
cells,erythroid |
R1348 |
T2294 |
T2293 |
arg1Of |
mechanism,The |
R1349 |
T2201 |
T2199 |
arg2Of |
set,by |
R135 |
T343 |
T342 |
arg1Of |
assays,Transfection |
R1350 |
T2201 |
T2200 |
arg1Of |
set,a |
R1351 |
T2294 |
T2295 |
arg1Of |
mechanism,of |
R1352 |
T2294 |
T2305 |
arg1Of |
mechanism,has |
R1353 |
T2294 |
T2306 |
arg1Of |
mechanism,been |
R1354 |
T2294 |
T2307 |
arg2Of |
mechanism,studied |
R1355 |
T2296 |
T2295 |
arg2Of |
silencing,of |
R1356 |
T2296 |
T2297 |
arg1Of |
silencing,of |
R1357 |
T2300 |
T2297 |
arg2Of |
counterpart,of |
R13578 |
T19152 |
T19150 |
arg1Of |
extract,Nuclear |
R13579 |
T19152 |
T19151 |
arg1Of |
extract,protein |
R1358 |
T2300 |
T2298 |
arg1Of |
counterpart,its |
R13580 |
T19152 |
T19153 |
arg1Of |
extract,and |
R13581 |
T19155 |
T19154 |
arg1Of |
vitro,in |
R13582 |
T19156 |
T19153 |
arg2Of |
translation,and |
R13583 |
T19156 |
T19155 |
arg1Of |
translation,vitro |
R13584 |
T19156 |
T19157 |
arg1Of |
translation,of |
R13585 |
T19158 |
T19157 |
arg2Of |
Sox6,of |
R13586 |
T19160 |
T19159 |
arg1Of |
extracts,Nuclear |
R13587 |
T19160 |
T19161 |
arg1Of |
extracts,were |
R13588 |
T19160 |
T19162 |
arg2Of |
extracts,prepared |
R13589 |
T19162 |
T19161 |
arg2Of |
prepared,were |
R1359 |
T2300 |
T2299 |
arg1Of |
counterpart,human |
R13590 |
T19162 |
T19163 |
arg1Of |
prepared,from |
R13591 |
T19165 |
T19163 |
arg2Of |
cells,from |
R13592 |
T19165 |
T19164 |
arg1Of |
cells,MEL |
R13593 |
T19165 |
T19166 |
arg1Of |
cells,( |
R13594 |
T19165 |
T19171 |
arg1Of |
cells,using |
R13595 |
T19167 |
T19168 |
arg1Of |
2,× |
R13596 |
T19168 |
T19166 |
arg2Of |
×,( |
R13597 |
T19169 |
T19168 |
arg2Of |
107,× |
R13598 |
T19170 |
T19166 |
arg3Of |
),( |
R13599 |
T19173 |
T19171 |
arg2Of |
kit,using |
R136 |
T343 |
T344 |
arg1Of |
assays,in |
R1360 |
T2300 |
T2301 |
arg1Of |
counterpart,"," |
R13600 |
T19173 |
T19172 |
arg1Of |
kit,a |
R13601 |
T19173 |
T19174 |
arg1Of |
kit,( |
R13602 |
T19176 |
T19177 |
arg1Of |
Motif,"," |
R13603 |
T19177 |
T19179 |
arg1Of |
",","," |
R13604 |
T19178 |
T19177 |
arg2Of |
Carlsbad,"," |
R13605 |
T19179 |
T19175 |
arg1Of |
",",Active |
R13606 |
T19179 |
T19181 |
arg1Of |
",","," |
R13607 |
T19180 |
T19179 |
arg2Of |
California,"," |
R13608 |
T19181 |
T19174 |
arg2Of |
",",( |
R13609 |
T19183 |
T19181 |
arg2Of |
States,"," |
R1361 |
T2201 |
T2202 |
arg1Of |
set,of |
R13610 |
T19183 |
T19182 |
arg1Of |
States,United |
R13611 |
T19184 |
T19174 |
arg3Of |
),( |
R13612 |
T19188 |
T19187 |
arg1Of |
vitro,in |
R13613 |
T19191 |
T19185 |
arg1Of |
vector,The |
R13614 |
T19191 |
T19186 |
arg1Of |
vector,Sox6 |
R13615 |
T19191 |
T19188 |
arg1Of |
vector,vitro |
R13616 |
T19191 |
T19189 |
arg1Of |
vector,translation |
R13617 |
T19191 |
T19190 |
arg1Of |
vector,expression |
R13618 |
T19191 |
T19192 |
arg1Of |
vector,"," |
R13619 |
T19191 |
T19193 |
arg2Of |
vector,tagged |
R1362 |
T2205 |
T2202 |
arg2Of |
sites,of |
R13620 |
T19191 |
T19199 |
arg1Of |
vector,was |
R13621 |
T19191 |
T19200 |
arg2Of |
vector,described |
R13622 |
T19193 |
T19194 |
arg1Of |
tagged,with |
R13623 |
T19195 |
T19196 |
arg1Of |
c-Myc,and |
R13624 |
T19196 |
T19194 |
arg2Of |
and,with |
R13625 |
T19197 |
T19196 |
arg2Of |
HA,and |
R13626 |
T19200 |
T19198 |
arg1Of |
described,"," |
R13627 |
T19200 |
T19199 |
arg2Of |
described,was |
R13628 |
T19200 |
T19201 |
arg1Of |
described,before |
R13629 |
T19203 |
T19201 |
arg2Of |
15,before |
R1363 |
T2303 |
T2301 |
arg2Of |
globin,"," |
R13630 |
T19203 |
T19202 |
arg2Of |
15,[ |
R13631 |
T19204 |
T19202 |
arg3Of |
],[ |
R13632 |
T19206 |
T19205 |
arg1Of |
translation,The |
R13633 |
T19206 |
T19207 |
arg1Of |
translation,was |
R13634 |
T19206 |
T19208 |
arg2Of |
translation,performed |
R13635 |
T19208 |
T19207 |
arg2Of |
performed,was |
R13636 |
T19208 |
T19209 |
arg1Of |
performed,in |
R13637 |
T19212 |
T19209 |
arg2Of |
lysate,in |
R13638 |
T19212 |
T19210 |
arg1Of |
lysate,a |
R13639 |
T19212 |
T19211 |
arg1Of |
lysate,reticulocyte |
R1364 |
T2303 |
T2302 |
arg1Of |
globin,ɛ |
R13640 |
T19212 |
T19213 |
arg2Of |
lysate,based |
R13641 |
T19213 |
T19215 |
arg1Of |
based,vitro |
R13642 |
T19215 |
T19214 |
arg1Of |
vitro,in |
R13643 |
T19217 |
T19209 |
arg3Of |
system,in |
R13644 |
T19217 |
T19216 |
arg1Of |
system,translational |
R13645 |
T19217 |
T19218 |
arg1Of |
system,( |
R13646 |
T19223 |
T19218 |
arg2Of |
Systems,( |
R13647 |
T19223 |
T19219 |
arg1Of |
Systems,TNT® |
R13648 |
T19223 |
T19220 |
arg1Of |
Systems,Quick |
R13649 |
T19223 |
T19221 |
arg1Of |
Systems,Coupled |
R1365 |
T2307 |
T2304 |
arg1Of |
studied,"," |
R13650 |
T19223 |
T19222 |
arg1Of |
Systems,Transcription/Translation |
R13651 |
T19223 |
T19224 |
arg1Of |
Systems,"," |
R13652 |
T19223 |
T19225 |
arg1Of |
Systems,Promega |
R13653 |
T19226 |
T19218 |
arg3Of |
),( |
R13654 |
T19228 |
T19227 |
arg1Of |
vector,A |
R13655 |
T19228 |
T19229 |
arg1Of |
vector,without |
R13656 |
T19228 |
T19234 |
arg1Of |
vector,was |
R13657 |
T19228 |
T19236 |
arg2Of |
vector,translated |
R13658 |
T19233 |
T19229 |
arg2Of |
sequence,without |
R13659 |
T19233 |
T19230 |
arg1Of |
sequence,the |
R1366 |
T2307 |
T2305 |
arg2Of |
studied,has |
R13660 |
T19233 |
T19231 |
arg1Of |
sequence,Sox6 |
R13661 |
T19233 |
T19232 |
arg1Of |
sequence,coding |
R13662 |
T19236 |
T19234 |
arg2Of |
translated,was |
R13663 |
T19236 |
T19235 |
arg1Of |
translated,also |
R13664 |
T19236 |
T19237 |
arg1Of |
translated,as |
R13665 |
T19240 |
T19237 |
arg2Of |
control,as |
R13666 |
T19240 |
T19238 |
arg1Of |
control,a |
R13667 |
T19240 |
T19239 |
arg1Of |
control,negative |
R1367 |
T2307 |
T2306 |
arg2Of |
studied,been |
R1368 |
T2307 |
T2308 |
arg1Of |
studied,extensively |
R1369 |
T2205 |
T2203 |
arg1Of |
sites,nuclease |
R137 |
T343 |
T350 |
arg1Of |
assays,define |
R1370 |
T2311 |
T2309 |
arg2Of |
erythropoiesis,In |
R1371 |
T2311 |
T2310 |
arg1Of |
erythropoiesis,definitive |
R1372 |
T2205 |
T2204 |
arg1Of |
sites,hypersensitive |
R1373 |
T2205 |
T2206 |
arg2Of |
sites,spread |
R1374 |
T2313 |
T2314 |
arg1Of |
ɛ,is |
R1375 |
T2313 |
T2315 |
arg2Of |
ɛ,activated |
R1376 |
T2313 |
T2317 |
arg2Of |
ɛ,silenced |
R1377 |
T2206 |
T2207 |
arg1Of |
spread,over |
R13772 |
T19429 |
T19428 |
arg1Of |
antibodies,Sox6 |
R13773 |
T19429 |
T19430 |
arg2Of |
antibodies,used |
R13774 |
T19429 |
T19434 |
arg1Of |
antibodies,were |
R13775 |
T19429 |
T19437 |
arg2Of |
antibodies,provided |
R13776 |
T19429 |
T19454 |
arg2Of |
antibodies,obtained |
R13777 |
T19430 |
T19431 |
arg1Of |
used,in |
R13778 |
T19433 |
T19431 |
arg2Of |
study,in |
R13779 |
T19433 |
T19432 |
arg1Of |
study,this |
R1378 |
T2315 |
T2316 |
arg1Of |
activated,and |
R13780 |
T19437 |
T19436 |
arg1Of |
provided,kindly |
R13781 |
T19437 |
T19452 |
arg1Of |
provided,or |
R13782 |
T19441 |
T19437 |
arg1Of |
Lalli,provided |
R13783 |
T19441 |
T19438 |
arg2Of |
Lalli,by |
R13784 |
T19441 |
T19439 |
arg1Of |
Lalli,Dr. |
R13785 |
T19441 |
T19440 |
arg1Of |
Lalli,Enzo |
R13786 |
T19441 |
T19442 |
arg1Of |
Lalli,( |
R13787 |
T19445 |
T19443 |
arg1Of |
Pasteur,Université |
R13788 |
T19445 |
T19444 |
arg1Of |
Pasteur,Louis |
R13789 |
T19445 |
T19446 |
arg1Of |
Pasteur,"," |
R1379 |
T2316 |
T2309 |
arg1Of |
and,In |
R13790 |
T19446 |
T19442 |
arg2Of |
",",( |
R13791 |
T19447 |
T19446 |
arg2Of |
France,"," |
R13792 |
T19447 |
T19448 |
arg1Of |
France,[ |
R13793 |
T19449 |
T19448 |
arg2Of |
7,[ |
R13794 |
T19450 |
T19448 |
arg3Of |
],[ |
R13795 |
T19451 |
T19442 |
arg3Of |
),( |
R13796 |
T19452 |
T19434 |
arg2Of |
or,were |
R13797 |
T19452 |
T19435 |
arg1Of |
or,either |
R13798 |
T19454 |
T19452 |
arg2Of |
obtained,or |
R13799 |
T19454 |
T19453 |
arg1Of |
obtained,commercially |
R138 |
T347 |
T346 |
arg2Of |
erythroleukemic,( |
R1380 |
T2316 |
T2312 |
arg1Of |
and,"," |
R13800 |
T19454 |
T19455 |
arg1Of |
obtained,( |
R13801 |
T19459 |
T19455 |
arg2Of |
X,( |
R13802 |
T19459 |
T19456 |
arg1Of |
X,Catalog |
R13803 |
T19459 |
T19457 |
arg1Of |
X,No. |
R13804 |
T19459 |
T19458 |
arg1Of |
X,sc-17332 |
R13805 |
T19459 |
T19460 |
arg1Of |
X,"," |
R13806 |
T19459 |
T19469 |
arg1Of |
X,"," |
R13807 |
T19463 |
T19460 |
arg2Of |
Biotechnology,"," |
R13808 |
T19463 |
T19461 |
arg1Of |
Biotechnology,Santa |
R13809 |
T19463 |
T19462 |
arg1Of |
Biotechnology,Cruz |
R1381 |
T2316 |
T2314 |
arg2Of |
and,is |
R13810 |
T19463 |
T19464 |
arg1Of |
Biotechnology,"," |
R13811 |
T19466 |
T19465 |
arg1Of |
Cruz,Santa |
R13812 |
T19466 |
T19467 |
arg1Of |
Cruz,"," |
R13813 |
T19467 |
T19464 |
arg2Of |
",","," |
R13814 |
T19468 |
T19467 |
arg2Of |
California,"," |
R13815 |
T19471 |
T19469 |
arg2Of |
States,"," |
R13816 |
T19471 |
T19470 |
arg1Of |
States,United |
R13817 |
T19472 |
T19455 |
arg3Of |
),( |
R13818 |
T19474 |
T19473 |
arg1Of |
Sox6,All |
R13819 |
T19474 |
T19481 |
arg1Of |
Sox6,was |
R1382 |
T2316 |
T2319 |
arg1Of |
and,[ |
R13820 |
T19474 |
T19482 |
arg2Of |
Sox6,purchased |
R13821 |
T19475 |
T19476 |
arg1Of |
antibodies,generated |
R13822 |
T19480 |
T19476 |
arg2Of |
antibody,generated |
R13823 |
T19480 |
T19477 |
arg1Of |
antibody,similar |
R13824 |
T19480 |
T19478 |
arg1Of |
antibody,results. |
R13825 |
T19480 |
T19479 |
arg1Of |
antibody,c-Myc |
R13826 |
T19482 |
T19476 |
arg3Of |
purchased,generated |
R13827 |
T19482 |
T19481 |
arg2Of |
purchased,was |
R13828 |
T19482 |
T19483 |
arg1Of |
purchased,from |
R13829 |
T19485 |
T19483 |
arg2Of |
Normal,from |
R1383 |
T2316 |
T2322 |
arg1Of |
and,"," |
R13830 |
T19485 |
T19484 |
arg1Of |
Normal,Invitrogen. |
R13831 |
T19488 |
T19486 |
arg1Of |
antibody,rabbit |
R13832 |
T19488 |
T19487 |
arg1Of |
antibody,IgG |
R13833 |
T19488 |
T19489 |
arg1Of |
antibody,was |
R13834 |
T19488 |
T19490 |
arg2Of |
antibody,obtained |
R13835 |
T19490 |
T19481 |
modOf |
obtained,was |
R13836 |
T19490 |
T19489 |
arg2Of |
obtained,was |
R13837 |
T19490 |
T19491 |
arg1Of |
obtained,from |
R13838 |
T19493 |
T19491 |
arg2Of |
Biotechnology,from |
R13839 |
T19493 |
T19492 |
arg1Of |
Biotechnology,Upstate |
R1384 |
T2316 |
T2323 |
arg1Of |
and,although |
R13840 |
T19493 |
T19494 |
arg1Of |
Biotechnology,( |
R13841 |
T19496 |
T19494 |
arg2Of |
Placid,( |
R13842 |
T19496 |
T19495 |
arg1Of |
Placid,Lake |
R13843 |
T19496 |
T19497 |
arg1Of |
Placid,"," |
R13844 |
T19496 |
T19500 |
arg1Of |
Placid,"," |
R13845 |
T19499 |
T19497 |
arg2Of |
York,"," |
R13846 |
T19499 |
T19498 |
arg1Of |
York,New |
R13847 |
T19502 |
T19500 |
arg2Of |
States,"," |
R13848 |
T19502 |
T19501 |
arg1Of |
States,United |
R13849 |
T19503 |
T19494 |
arg3Of |
),( |
R1385 |
T2317 |
T2316 |
arg2Of |
silenced,and |
R1386 |
T2317 |
T2318 |
arg1Of |
silenced,autonomously |
R1387 |
T2206 |
T2216 |
arg1Of |
spread,[ |
R1388 |
T2320 |
T2319 |
arg2Of |
"24,25",[ |
R1389 |
T2211 |
T2207 |
arg2Of |
5′,over |
R139 |
T348 |
T346 |
arg3Of |
),( |
R1390 |
T2321 |
T2319 |
arg3Of |
],[ |
R1391 |
T2326 |
T2324 |
arg2Of |
erythropoiesis,in |
R1392 |
T2326 |
T2325 |
arg1Of |
erythropoiesis,primitive |
R1393 |
T2327 |
T2329 |
arg1Of |
ɛ,appears |
R13935 |
T19697 |
T19695 |
arg1Of |
oligonucleotides,Single-stranded |
R13936 |
T19697 |
T19696 |
arg1Of |
oligonucleotides,complementary |
R13937 |
T19697 |
T19698 |
arg1Of |
oligonucleotides,were |
R13938 |
T19697 |
T19699 |
arg2Of |
oligonucleotides,annealed |
R13939 |
T19697 |
T19701 |
arg2Of |
oligonucleotides,end-labeled |
R1394 |
T2327 |
T2331 |
arg1Of |
ɛ,be |
R13940 |
T19699 |
T19700 |
arg1Of |
annealed,and |
R13941 |
T19700 |
T19698 |
arg2Of |
and,were |
R13942 |
T19701 |
T19700 |
arg2Of |
end-labeled,and |
R13943 |
T19701 |
T19702 |
arg1Of |
end-labeled,with |
R13944 |
T19704 |
T19703 |
arg2Of |
γ-32P,[ |
R13945 |
T19705 |
T19703 |
arg3Of |
],[ |
R13946 |
T19706 |
T19702 |
arg2Of |
ATP,with |
R13947 |
T19706 |
T19703 |
arg1Of |
ATP,[ |
R13948 |
T19706 |
T19707 |
arg1Of |
ATP,with |
R13949 |
T19710 |
T19707 |
arg2Of |
kinase,with |
R1395 |
T2211 |
T2208 |
arg1Of |
5′,25 |
R13950 |
T19710 |
T19708 |
arg1Of |
kinase,T4 |
R13951 |
T19710 |
T19709 |
arg1Of |
kinase,polynucleotide |
R13952 |
T19711 |
T19712 |
arg1Of |
EMSA,was |
R13953 |
T19711 |
T19713 |
arg2Of |
EMSA,performed |
R13954 |
T19713 |
T19712 |
arg2Of |
performed,was |
R13955 |
T19713 |
T19714 |
arg1Of |
performed,with |
R13956 |
T19713 |
T19738 |
arg1Of |
performed,: |
R13957 |
T19716 |
T19715 |
arg1Of |
μg,5 |
R13958 |
T19716 |
T19717 |
arg1Of |
μg,of |
R13959 |
T19716 |
T19723 |
arg1Of |
μg,or |
R1396 |
T2327 |
T2332 |
arg2Of |
ɛ,regulated |
R13960 |
T19719 |
T19717 |
arg2Of |
proteins,of |
R13961 |
T19719 |
T19718 |
arg1Of |
proteins,nuclear |
R13962 |
T19719 |
T19720 |
arg1Of |
proteins,from |
R13963 |
T19722 |
T19720 |
arg2Of |
cells,from |
R13964 |
T19722 |
T19721 |
arg1Of |
cells,MEL |
R13965 |
T19723 |
T19714 |
arg2Of |
or,with |
R13966 |
T19723 |
T19731 |
arg1Of |
or,with |
R13967 |
T19725 |
T19723 |
arg2Of |
μl,or |
R13968 |
T19725 |
T19724 |
arg1Of |
μl,3 |
R13969 |
T19725 |
T19726 |
arg1Of |
μl,of |
R1397 |
T2211 |
T2209 |
arg1Of |
5′,kb |
R13970 |
T19728 |
T19727 |
arg1Of |
vitro-translated,in |
R13971 |
T19729 |
T19726 |
arg2Of |
Sox6,of |
R13972 |
T19729 |
T19728 |
arg1Of |
Sox6,vitro-translated |
R13973 |
T19731 |
T19730 |
arg1Of |
with,along |
R13974 |
T19734 |
T19731 |
arg2Of |
lysate,with |
R13975 |
T19734 |
T19732 |
arg1Of |
lysate,the |
R13976 |
T19734 |
T19733 |
arg1Of |
lysate,reticulocyte |
R13977 |
T19734 |
T19735 |
arg1Of |
lysate,in |
R13978 |
T19737 |
T19735 |
arg2Of |
buffer,in |
R13979 |
T19737 |
T19736 |
arg1Of |
buffer,binding |
R1398 |
T2329 |
T2323 |
arg2Of |
appears,although |
R13980 |
T19739 |
T19740 |
arg1Of |
100,mM |
R13981 |
T19741 |
T19739 |
arg1Of |
NaCl,100 |
R13982 |
T19741 |
T19742 |
arg1Of |
NaCl,"," |
R13983 |
T19742 |
T19746 |
arg1Of |
",","," |
R13984 |
T19743 |
T19744 |
arg1Of |
10,% |
R13985 |
T19745 |
T19742 |
arg2Of |
glycerol,"," |
R13986 |
T19745 |
T19743 |
arg1Of |
glycerol,10 |
R13987 |
T19746 |
T19750 |
arg1Of |
",","," |
R13988 |
T19749 |
T19746 |
arg2Of |
BSA,"," |
R13989 |
T19749 |
T19747 |
arg1Of |
BSA,200 |
R1399 |
T2329 |
T2324 |
arg1Of |
appears,in |
R13990 |
T19749 |
T19748 |
arg1Of |
BSA,ng/μl |
R13991 |
T19750 |
T19757 |
arg1Of |
",",or |
R13992 |
T19753 |
T19750 |
arg2Of |
poly,"," |
R13993 |
T19753 |
T19751 |
arg1Of |
poly,50 |
R13994 |
T19753 |
T19752 |
arg1Of |
poly,ng/μl |
R13995 |
T19753 |
T19754 |
arg1Of |
poly,( |
R13996 |
T19755 |
T19754 |
arg2Of |
dI-dC,( |
R13997 |
T19756 |
T19754 |
arg3Of |
),( |
R13998 |
T19757 |
T19770 |
arg1Of |
or,"," |
R13999 |
T19758 |
T19759 |
arg1Of |
poly,( |
R140 |
T349 |
T344 |
arg2Of |
cells,in |
R1400 |
T2329 |
T2328 |
arg1Of |
appears,also |
R14000 |
T19758 |
T19762 |
arg1Of |
poly,"," |
R14001 |
T19760 |
T19759 |
arg2Of |
dG-dC,( |
R14002 |
T19761 |
T19759 |
arg3Of |
),( |
R14003 |
T19762 |
T19757 |
arg2Of |
",",or |
R14004 |
T19763 |
T19764 |
arg1Of |
10,mM |
R14005 |
T19765 |
T19762 |
arg2Of |
HEPES,"," |
R14006 |
T19765 |
T19763 |
arg1Of |
HEPES,10 |
R14007 |
T19765 |
T19766 |
arg1Of |
HEPES,( |
R14008 |
T19767 |
T19766 |
arg2Of |
pH,( |
R14009 |
T19767 |
T19768 |
arg1Of |
pH,7 |
R1401 |
T2211 |
T2210 |
arg1Of |
5′,located |
R14010 |
T19769 |
T19766 |
arg3Of |
),( |
R14011 |
T19771 |
T19772 |
arg1Of |
0.1,mM |
R14012 |
T19773 |
T19770 |
arg2Of |
EDTA,"," |
R14013 |
T19773 |
T19771 |
arg1Of |
EDTA,0.1 |
R14014 |
T19773 |
T19774 |
arg1Of |
EDTA,"," |
R14015 |
T19773 |
T19778 |
arg1Of |
EDTA,"," |
R14016 |
T19775 |
T19776 |
arg1Of |
0.25,mM |
R14017 |
T19777 |
T19774 |
arg2Of |
DTT,"," |
R14018 |
T19777 |
T19775 |
arg1Of |
DTT,0.25 |
R14019 |
T19779 |
T19780 |
arg1Of |
0.6,mM |
R1402 |
T2211 |
T2212 |
arg1Of |
5′,of |
R14020 |
T19781 |
T19778 |
arg2Of |
MgCl2,"," |
R14021 |
T19781 |
T19779 |
arg1Of |
MgCl2,0.6 |
R14022 |
T19783 |
T19784 |
arg1Of |
competition,or |
R14023 |
T19784 |
T19782 |
arg2Of |
or,For |
R14024 |
T19786 |
T19784 |
arg2Of |
assays,or |
R14025 |
T19786 |
T19785 |
arg1Of |
assays,supershift |
R14026 |
T19792 |
T19789 |
arg2Of |
competitor,indicated |
R14027 |
T19792 |
T19790 |
arg1Of |
competitor,unlabelled |
R14028 |
T19792 |
T19791 |
arg1Of |
competitor,oligonucleotide |
R14029 |
T19792 |
T19793 |
arg1Of |
competitor,( |
R1403 |
T2332 |
T2329 |
arg2Of |
regulated,appears |
R14030 |
T19792 |
T19798 |
arg1Of |
competitor,or |
R14031 |
T19796 |
T19793 |
arg2Of |
excess,( |
R14032 |
T19796 |
T19794 |
arg1Of |
excess,200-fold |
R14033 |
T19796 |
T19795 |
arg1Of |
excess,molar |
R14034 |
T19797 |
T19793 |
arg3Of |
),( |
R14035 |
T19798 |
T19788 |
arg1Of |
or,the |
R14036 |
T19798 |
T19804 |
arg1Of |
or,was |
R14037 |
T19798 |
T19805 |
arg2Of |
or,added |
R14038 |
T19799 |
T19798 |
arg2Of |
antibody,or |
R14039 |
T19799 |
T19800 |
arg1Of |
antibody,( |
R1404 |
T2332 |
T2330 |
arg1Of |
regulated,to |
R14040 |
T19802 |
T19800 |
arg2Of |
μl,( |
R14041 |
T19802 |
T19801 |
arg1Of |
μl,3 |
R14042 |
T19803 |
T19800 |
arg3Of |
),( |
R14043 |
T19805 |
T19782 |
arg1Of |
added,For |
R14044 |
T19805 |
T19787 |
arg1Of |
added,"," |
R14045 |
T19805 |
T19804 |
arg2Of |
added,was |
R14046 |
T19806 |
T19808 |
arg1Of |
30,to |
R14047 |
T19808 |
T19807 |
arg1Of |
to,min |
R14048 |
T19809 |
T19808 |
arg2Of |
60,to |
R14049 |
T19810 |
T19805 |
arg3Of |
min,added |
R1405 |
T2332 |
T2331 |
arg2Of |
regulated,be |
R14050 |
T19810 |
T19806 |
arg1Of |
min,30 |
R14051 |
T19810 |
T19811 |
arg1Of |
min,prior |
R14052 |
T19811 |
T19812 |
arg1Of |
prior,to |
R14053 |
T19813 |
T19812 |
arg2Of |
addition,to |
R14054 |
T19813 |
T19814 |
arg1Of |
addition,of |
R14055 |
T19816 |
T19814 |
arg2Of |
probe,of |
R14056 |
T19816 |
T19815 |
arg2Of |
probe,radiolabeled |
R14057 |
T19818 |
T19817 |
arg2Of |
addition,Following |
R14058 |
T19818 |
T19819 |
arg1Of |
addition,of |
R14059 |
T19822 |
T19819 |
arg2Of |
probe,of |
R1406 |
T2332 |
T2333 |
arg1Of |
regulated,competitively |
R14060 |
T19822 |
T19820 |
arg1Of |
probe,the |
R14061 |
T19822 |
T19821 |
arg2Of |
probe,radiolabeled |
R14062 |
T19825 |
T19824 |
arg1Of |
samples,the |
R14063 |
T19825 |
T19826 |
arg1Of |
samples,were |
R14064 |
T19825 |
T19827 |
arg2Of |
samples,incubated |
R14065 |
T19825 |
T19838 |
arg2Of |
samples,loaded |
R14066 |
T19827 |
T19828 |
arg1Of |
incubated,for |
R14067 |
T19827 |
T19837 |
arg1Of |
incubated,and |
R14068 |
T19830 |
T19829 |
arg1Of |
min,30 |
R14069 |
T19830 |
T19831 |
arg1Of |
min,or |
R1407 |
T2332 |
T2334 |
arg1Of |
regulated,[ |
R14070 |
T19831 |
T19828 |
arg2Of |
or,for |
R14071 |
T19831 |
T19834 |
arg1Of |
or,at |
R14072 |
T19833 |
T19831 |
arg2Of |
min,or |
R14073 |
T19833 |
T19832 |
arg1Of |
min,60 |
R14074 |
T19836 |
T19834 |
arg2Of |
temperature,at |
R14075 |
T19836 |
T19835 |
arg1Of |
temperature,room |
R14076 |
T19837 |
T19817 |
arg1Of |
and,Following |
R14077 |
T19837 |
T19823 |
arg1Of |
and,"," |
R14078 |
T19837 |
T19826 |
arg2Of |
and,were |
R14079 |
T19838 |
T19837 |
arg2Of |
loaded,and |
R1408 |
T2335 |
T2334 |
arg2Of |
26,[ |
R14080 |
T19838 |
T19839 |
arg1Of |
loaded,on |
R14081 |
T19842 |
T19843 |
arg1Of |
%,or |
R14082 |
T19843 |
T19841 |
arg1Of |
or,4 |
R14083 |
T19844 |
T19843 |
arg2Of |
6,or |
R14084 |
T19845 |
T19839 |
arg2Of |
%,on |
R14085 |
T19845 |
T19840 |
arg1Of |
%,a |
R14086 |
T19845 |
T19842 |
arg1Of |
%,% |
R14087 |
T19845 |
T19844 |
arg1Of |
%,6 |
R14088 |
T19847 |
T19846 |
arg2Of |
w/v,( |
R14089 |
T19848 |
T19846 |
arg3Of |
),( |
R1409 |
T2336 |
T2334 |
arg3Of |
],[ |
R14090 |
T19850 |
T19838 |
arg3Of |
gel,loaded |
R14091 |
T19850 |
T19846 |
arg1Of |
gel,( |
R14092 |
T19850 |
T19849 |
arg1Of |
gel,polyacrylamide |
R14093 |
T19851 |
T19852 |
arg1Of |
Electrophoresis,was |
R14094 |
T19851 |
T19853 |
arg2Of |
Electrophoresis,performed |
R14095 |
T19853 |
T19852 |
arg2Of |
performed,was |
R14096 |
T19853 |
T19854 |
arg1Of |
performed,at |
R14097 |
T19853 |
T19859 |
arg1Of |
performed,for |
R14098 |
T19853 |
T19862 |
arg1Of |
performed,at |
R14099 |
T19853 |
T19866 |
arg1Of |
performed,and |
R141 |
T349 |
T345 |
arg1Of |
cells,GM979 |
R1410 |
T2215 |
T2212 |
arg2Of |
gene,of |
R14100 |
T19858 |
T19854 |
arg2Of |
mAmp,at |
R14101 |
T19858 |
T19855 |
arg1Of |
mAmp,a |
R14102 |
T19858 |
T19856 |
arg1Of |
mAmp,constant |
R14103 |
T19858 |
T19857 |
arg1Of |
mAmp,19 |
R14104 |
T19861 |
T19859 |
arg2Of |
h,for |
R14105 |
T19861 |
T19860 |
arg1Of |
h,4–8 |
R14106 |
T19864 |
T19862 |
arg2Of |
temperature,at |
R14107 |
T19864 |
T19863 |
arg1Of |
temperature,room |
R14108 |
T19866 |
T19865 |
arg1Of |
and,"," |
R14109 |
T19868 |
T19867 |
arg1Of |
gels,the |
R1411 |
T2338 |
T2337 |
arg1Of |
γ-globin,The |
R14110 |
T19868 |
T19869 |
arg1Of |
gels,were |
R14111 |
T19868 |
T19870 |
arg2Of |
gels,dried |
R14112 |
T19870 |
T19866 |
arg2Of |
dried,and |
R14113 |
T19870 |
T19869 |
arg2Of |
dried,were |
R14114 |
T19870 |
T19871 |
arg1Of |
dried,prior |
R14115 |
T19871 |
T19872 |
arg1Of |
prior,to |
R14116 |
T19873 |
T19872 |
arg2Of |
autoradiography,to |
R14117 |
T19874 |
T19875 |
arg2Of |
Antibodies,used |
R14118 |
T19874 |
T19879 |
arg1Of |
Antibodies,included |
R14119 |
T19875 |
T19876 |
arg1Of |
used,for |
R1412 |
T2338 |
T2339 |
arg1Of |
γ-globin,to |
R14120 |
T19878 |
T19876 |
arg2Of |
analyses,for |
R14121 |
T19878 |
T19877 |
arg1Of |
analyses,supershift |
R14122 |
T19880 |
T19881 |
arg1Of |
c-Myc,"," |
R14123 |
T19881 |
T19884 |
arg1Of |
",",and |
R14124 |
T19882 |
T19881 |
arg2Of |
HA,"," |
R14125 |
T19884 |
T19883 |
arg1Of |
and,"," |
R14126 |
T19885 |
T19884 |
arg2Of |
Sox6,and |
R14127 |
T19886 |
T19879 |
arg2Of |
antibodies,included |
R14128 |
T19886 |
T19880 |
arg1Of |
antibodies,c-Myc |
R14129 |
T19886 |
T19882 |
arg1Of |
antibodies,HA |
R1413 |
T2338 |
T2343 |
arg1Of |
γ-globin,is |
R14130 |
T19886 |
T19885 |
arg1Of |
antibodies,Sox6 |
R14131 |
T19886 |
T19887 |
arg1Of |
antibodies,( |
R14132 |
T19888 |
T19887 |
arg2Of |
described,( |
R14133 |
T19888 |
T19889 |
arg1Of |
described,as |
R14134 |
T19890 |
T19889 |
arg2Of |
above,as |
R14135 |
T19891 |
T19887 |
arg3Of |
),( |
R14136 |
T19894 |
T19892 |
arg1Of |
sequences,The |
R14137 |
T19894 |
T19893 |
arg1Of |
sequences,DNA |
R14138 |
T19894 |
T19895 |
arg1Of |
sequences,of |
R14139 |
T19894 |
T19898 |
arg1Of |
sequences,are |
R1414 |
T2338 |
T2344 |
arg2Of |
γ-globin,controlled |
R14140 |
T19894 |
T19899 |
arg1Of |
sequences,as |
R14141 |
T19897 |
T19895 |
arg2Of |
oligonucleotides,of |
R14142 |
T19897 |
T19896 |
arg1Of |
oligonucleotides,the |
R14143 |
T19898 |
T19901 |
arg1Of |
are,( |
R14144 |
T19898 |
T19908 |
arg1Of |
are,: |
R14145 |
T19899 |
T19898 |
arg2Of |
as,are |
R14146 |
T19900 |
T19899 |
arg2Of |
follows,as |
R14147 |
T19904 |
T19902 |
arg1Of |
oligos,only |
R14148 |
T19904 |
T19903 |
arg1Of |
oligos,forward |
R14149 |
T19904 |
T19905 |
arg1Of |
oligos,are |
R1415 |
T2342 |
T2339 |
arg2Of |
switch,to |
R14150 |
T19904 |
T19906 |
arg2Of |
oligos,listed |
R14151 |
T19906 |
T19901 |
arg2Of |
listed,( |
R14152 |
T19906 |
T19905 |
arg2Of |
listed,are |
R14153 |
T19907 |
T19901 |
arg3Of |
),( |
R14154 |
T19913 |
T19909 |
arg2Of |
probe,For |
R14155 |
T19913 |
T19910 |
arg1Of |
probe,the |
R14156 |
T19913 |
T19911 |
arg1Of |
probe,36-bp |
R14157 |
T19913 |
T19912 |
arg1Of |
probe,WT |
R14158 |
T19913 |
T19914 |
arg1Of |
probe,: |
R14159 |
T19915 |
T19916 |
arg1Of |
5′AATGCAGAACAAAGGGTCAGAACATTGTCTGCGAAG3′,( |
R1416 |
T2342 |
T2340 |
arg1Of |
switch,adult |
R14160 |
T19915 |
T19919 |
arg1Of |
5′AATGCAGAACAAAGGGTCAGAACATTGTCTGCGAAG3′,; |
R14161 |
T19915 |
T19920 |
arg1Of |
5′AATGCAGAACAAAGGGTCAGAACATTGTCTGCGAAG3′,for |
R14162 |
T19915 |
T19927 |
arg1Of |
5′AATGCAGAACAAAGGGTCAGAACATTGTCTGCGAAG3′,: |
R14163 |
T19917 |
T19916 |
arg2Of |
MHB1556,( |
R14164 |
T19918 |
T19916 |
arg3Of |
),( |
R14165 |
T19922 |
T19920 |
arg2Of |
probe,for |
R14166 |
T19922 |
T19921 |
arg1Of |
probe,mutant |
R14167 |
T19922 |
T19923 |
arg1Of |
probe,1 |
R14168 |
T19922 |
T19924 |
arg1Of |
probe,( |
R14169 |
T19925 |
T19924 |
arg2Of |
M1,( |
R1417 |
T2342 |
T2341 |
arg1Of |
switch,β-globin |
R14170 |
T19926 |
T19924 |
arg3Of |
),( |
R14171 |
T19928 |
T19929 |
arg1Of |
5′AACAAAGGGTCAGAACATTGTCTGCGAAG3′,( |
R14172 |
T19928 |
T19932 |
arg1Of |
5′AACAAAGGGTCAGAACATTGTCTGCGAAG3′,; |
R14173 |
T19928 |
T19933 |
arg1Of |
5′AACAAAGGGTCAGAACATTGTCTGCGAAG3′,for |
R14174 |
T19928 |
T19940 |
arg1Of |
5′AACAAAGGGTCAGAACATTGTCTGCGAAG3′,: |
R14175 |
T19930 |
T19929 |
arg2Of |
MHB1644,( |
R14176 |
T19931 |
T19929 |
arg3Of |
),( |
R14177 |
T19935 |
T19933 |
arg2Of |
probe,for |
R14178 |
T19935 |
T19934 |
arg1Of |
probe,mutant |
R14179 |
T19935 |
T19936 |
arg1Of |
probe,2 |
R1418 |
T2344 |
T2343 |
arg2Of |
controlled,is |
R14180 |
T19935 |
T19937 |
arg1Of |
probe,( |
R14181 |
T19938 |
T19937 |
arg2Of |
M2,( |
R14182 |
T19939 |
T19937 |
arg3Of |
),( |
R14183 |
T19941 |
T19942 |
arg1Of |
5′AATGCAGAACAAAGGGTCAGAtgagTGTCTGCGAAG3′,( |
R14184 |
T19941 |
T19945 |
arg1Of |
5′AATGCAGAACAAAGGGTCAGAtgagTGTCTGCGAAG3′,; |
R14185 |
T19941 |
T19946 |
arg1Of |
5′AATGCAGAACAAAGGGTCAGAtgagTGTCTGCGAAG3′,for |
R14186 |
T19941 |
T19953 |
arg1Of |
5′AATGCAGAACAAAGGGTCAGAtgagTGTCTGCGAAG3′,: |
R14187 |
T19943 |
T19942 |
arg2Of |
MHB1648,( |
R14188 |
T19944 |
T19942 |
arg3Of |
),( |
R14189 |
T19948 |
T19946 |
arg2Of |
probe,for |
R1419 |
T2344 |
T2351 |
arg1Of |
controlled,[ |
R14190 |
T19948 |
T19947 |
arg1Of |
probe,mutant |
R14191 |
T19948 |
T19949 |
arg1Of |
probe,3 |
R14192 |
T19948 |
T19950 |
arg1Of |
probe,( |
R14193 |
T19951 |
T19950 |
arg2Of |
M3,( |
R14194 |
T19952 |
T19950 |
arg3Of |
),( |
R14195 |
T19954 |
T19955 |
arg1Of |
5′AATGCAGtgccAAGGGTCAGAACATTGTCTGCGAAG3′,( |
R14196 |
T19956 |
T19955 |
arg2Of |
MHB1650,( |
R14197 |
T19957 |
T19955 |
arg3Of |
),( |
R142 |
T349 |
T346 |
arg1Of |
cells,( |
R1420 |
T2215 |
T2213 |
arg1Of |
gene,the |
R1421 |
T2215 |
T2214 |
arg1Of |
gene,ɛy |
R1422 |
T2347 |
T2344 |
arg1Of |
competition,controlled |
R1423 |
T2347 |
T2345 |
arg2Of |
competition,by |
R1424 |
T2347 |
T2346 |
arg1Of |
competition,promoter |
R1425 |
T2347 |
T2348 |
arg1Of |
competition,for |
R1426 |
T2217 |
T2216 |
arg2Of |
23,[ |
R1427 |
T2350 |
T2348 |
arg2Of |
LCR,for |
R1428 |
T2350 |
T2349 |
arg1Of |
LCR,the |
R1429 |
T2352 |
T2351 |
arg2Of |
"24,25",[ |
R143 |
T354 |
T350 |
arg2Of |
region,define |
R1430 |
T2218 |
T2216 |
arg3Of |
],[ |
R1431 |
T2353 |
T2351 |
arg3Of |
],[ |
R1432 |
T2221 |
T2219 |
arg1Of |
genes,The |
R1433 |
T2356 |
T2354 |
arg1Of |
elements,All |
R1434 |
T2356 |
T2355 |
arg1Of |
elements,the |
R1435 |
T2356 |
T2357 |
arg1Of |
elements,responsible |
R1436 |
T2356 |
T2364 |
arg1Of |
elements,are |
R1437 |
T2356 |
T2365 |
arg1Of |
elements,within |
R1438 |
T2356 |
T2370 |
arg1Of |
elements,in |
R1439 |
T2357 |
T2358 |
arg1Of |
responsible,for |
R144 |
T354 |
T351 |
arg1Of |
region,a |
R1440 |
T2221 |
T2220 |
arg1Of |
genes,β-globin |
R1441 |
T2359 |
T2358 |
arg2Of |
silencing,for |
R1442 |
T2221 |
T2222 |
arg1Of |
genes,are |
R1443 |
T2221 |
T2223 |
arg2Of |
genes,expressed |
R1444 |
T2223 |
T2222 |
arg2Of |
expressed,are |
R1445 |
T2363 |
T2359 |
arg2Of |
gene,silencing |
R1446 |
T2363 |
T2360 |
arg1Of |
gene,the |
R1447 |
T2363 |
T2361 |
arg1Of |
gene,ɛ |
R1448 |
T2363 |
T2362 |
arg1Of |
gene,globin |
R14488 |
T20383 |
T20382 |
arg1Of |
assay,ChIP |
R14489 |
T20385 |
T20384 |
arg2Of |
described,As |
R1449 |
T2364 |
T2376 |
arg1Of |
are,"," |
R14490 |
T20387 |
T20385 |
arg1Of |
Nouzova,described |
R14491 |
T20387 |
T20386 |
arg2Of |
Nouzova,by |
R14492 |
T20387 |
T20388 |
arg1Of |
Nouzova,[ |
R14493 |
T20387 |
T20391 |
arg1Of |
Nouzova,"," |
R14494 |
T20387 |
T20392 |
arg1Of |
Nouzova,in |
R14495 |
T20387 |
T20394 |
arg1Of |
Nouzova,: |
R14496 |
T20389 |
T20388 |
arg2Of |
53,[ |
R14497 |
T20390 |
T20388 |
arg3Of |
],[ |
R14498 |
T20393 |
T20392 |
arg2Of |
brief,in |
R14499 |
T20395 |
T20396 |
arg1Of |
Cells,from |
R145 |
T354 |
T352 |
arg1Of |
region,36–base |
R1450 |
T2364 |
T2377 |
modOf |
are,suggesting |
R14500 |
T20395 |
T20413 |
arg1Of |
Cells,were |
R14501 |
T20395 |
T20414 |
arg2Of |
Cells,treated |
R14502 |
T20398 |
T20397 |
arg1Of |
cells,MEL |
R14503 |
T20398 |
T20399 |
arg1Of |
cells,( |
R14504 |
T20398 |
T20404 |
arg1Of |
cells,or |
R14505 |
T20401 |
T20399 |
arg2Of |
×,( |
R14506 |
T20401 |
T20400 |
arg1Of |
×,4 |
R14507 |
T20401 |
T20402 |
arg1Of |
×,107 |
R14508 |
T20403 |
T20399 |
arg3Of |
),( |
R14509 |
T20404 |
T20396 |
arg2Of |
or,from |
R1451 |
T2365 |
T2369 |
arg1Of |
within,or |
R14510 |
T20407 |
T20404 |
arg2Of |
cells,or |
R14511 |
T20407 |
T20405 |
arg1Of |
cells,fetal |
R14512 |
T20407 |
T20406 |
arg1Of |
cells,liver |
R14513 |
T20407 |
T20408 |
arg1Of |
cells,from |
R14514 |
T20412 |
T20408 |
arg2Of |
mice,from |
R14515 |
T20412 |
T20409 |
arg1Of |
mice,three |
R14516 |
T20412 |
T20410 |
arg1Of |
mice,15.5-dpc |
R14517 |
T20412 |
T20411 |
arg1Of |
mice,WT |
R14518 |
T20414 |
T20413 |
arg2Of |
treated,were |
R14519 |
T20414 |
T20415 |
arg1Of |
treated,with |
R1452 |
T2223 |
T2224 |
arg1Of |
expressed,in |
R14520 |
T20416 |
T20417 |
arg1Of |
1,% |
R14521 |
T20418 |
T20415 |
arg2Of |
formaldehyde,with |
R14522 |
T20418 |
T20416 |
arg1Of |
formaldehyde,1 |
R14523 |
T20418 |
T20419 |
arg1Of |
formaldehyde,for |
R14524 |
T20421 |
T20419 |
arg2Of |
min,for |
R14525 |
T20421 |
T20420 |
arg1Of |
min,10 |
R14526 |
T20421 |
T20422 |
arg1Of |
min,at |
R14527 |
T20421 |
T20425 |
arg1Of |
min,"," |
R14528 |
T20421 |
T20426 |
arg2Of |
min,rinsed |
R14529 |
T20421 |
T20435 |
arg1Of |
min,with |
R1453 |
T2226 |
T2227 |
arg1Of |
tissue-,and |
R14530 |
T20424 |
T20422 |
arg2Of |
°C,at |
R14531 |
T20424 |
T20423 |
arg1Of |
°C,37 |
R14532 |
T20426 |
T20427 |
arg1Of |
rinsed,in |
R14533 |
T20430 |
T20431 |
arg2Of |
Hanks,' |
R14534 |
T20434 |
T20427 |
arg2Of |
solution,in |
R14535 |
T20434 |
T20428 |
arg1Of |
solution,ice-cold |
R14536 |
T20434 |
T20429 |
arg1Of |
solution,1× |
R14537 |
T20434 |
T20431 |
arg1Of |
solution,' |
R14538 |
T20434 |
T20432 |
arg1Of |
solution,balanced |
R14539 |
T20434 |
T20433 |
arg1Of |
solution,salt |
R1454 |
T2228 |
T2227 |
arg2Of |
development-specific,and |
R14540 |
T20436 |
T20437 |
arg1Of |
0.1,% |
R14541 |
T20438 |
T20435 |
arg2Of |
EDTA,with |
R14542 |
T20438 |
T20436 |
arg1Of |
EDTA,0.1 |
R14543 |
T20438 |
T20439 |
arg1Of |
EDTA,containing |
R14544 |
T20441 |
T20439 |
arg2Of |
inhibitors,containing |
R14545 |
T20441 |
T20440 |
arg1Of |
inhibitors,protease |
R14546 |
T20441 |
T20442 |
arg1Of |
inhibitors,"," |
R14547 |
T20441 |
T20443 |
arg2Of |
inhibitors,collected |
R14548 |
T20441 |
T20450 |
arg2Of |
inhibitors,resuspended |
R14549 |
T20441 |
T20461 |
arg2Of |
inhibitors,incubated |
R1455 |
T2368 |
T2365 |
arg2Of |
gene,within |
R14550 |
T20445 |
T20443 |
arg1Of |
centrifugation,collected |
R14551 |
T20445 |
T20444 |
arg2Of |
centrifugation,by |
R14552 |
T20445 |
T20446 |
arg1Of |
centrifugation,at |
R14553 |
T20448 |
T20446 |
arg2Of |
°C,at |
R14554 |
T20448 |
T20447 |
arg1Of |
°C,4 |
R14555 |
T20450 |
T20451 |
arg1Of |
resuspended,in |
R14556 |
T20450 |
T20460 |
arg1Of |
resuspended,and |
R14557 |
T20455 |
T20451 |
arg2Of |
buffer,in |
R14558 |
T20455 |
T20452 |
arg1Of |
buffer,a |
R14559 |
T20455 |
T20453 |
arg1Of |
buffer,SDS |
R1456 |
T2368 |
T2366 |
arg1Of |
gene,the |
R14560 |
T20455 |
T20454 |
arg1Of |
buffer,lysis |
R14561 |
T20455 |
T20456 |
arg1Of |
buffer,containing |
R14562 |
T20458 |
T20456 |
arg2Of |
inhibitors,containing |
R14563 |
T20458 |
T20457 |
arg1Of |
inhibitors,protease |
R14564 |
T20460 |
T20449 |
arg1Of |
and,"," |
R14565 |
T20460 |
T20459 |
arg1Of |
and,"," |
R14566 |
T20461 |
T20460 |
arg2Of |
incubated,and |
R14567 |
T20461 |
T20462 |
arg1Of |
incubated,on |
R14568 |
T20461 |
T20464 |
arg1Of |
incubated,for |
R14569 |
T20463 |
T20462 |
arg2Of |
ice,on |
R1457 |
T2368 |
T2367 |
arg1Of |
gene,ɛ |
R14570 |
T20466 |
T20464 |
arg2Of |
min,for |
R14571 |
T20466 |
T20465 |
arg1Of |
min,10 |
R14572 |
T20468 |
T20467 |
arg1Of |
complexes,DNA-protein |
R14573 |
T20468 |
T20469 |
arg1Of |
complexes,were |
R14574 |
T20468 |
T20470 |
arg2Of |
complexes,sonicated |
R14575 |
T20470 |
T20469 |
arg2Of |
sonicated,were |
R14576 |
T20470 |
T20471 |
arg1Of |
sonicated,to |
R14577 |
T20472 |
T20473 |
arg1Of |
200,and |
R14578 |
T20474 |
T20473 |
arg2Of |
600,and |
R14579 |
T20475 |
T20471 |
arg2Of |
bp,to |
R1458 |
T2369 |
T2364 |
arg2Of |
or,are |
R14580 |
T20475 |
T20472 |
arg1Of |
bp,200 |
R14581 |
T20475 |
T20474 |
arg1Of |
bp,600 |
R14582 |
T20476 |
T20477 |
arg1Of |
One-tenth,of |
R14583 |
T20476 |
T20480 |
arg1Of |
One-tenth,was |
R14584 |
T20476 |
T20481 |
arg2Of |
One-tenth,set |
R14585 |
T20479 |
T20477 |
arg2Of |
sample,of |
R14586 |
T20479 |
T20478 |
arg1Of |
sample,the |
R14587 |
T20481 |
T20480 |
arg2Of |
set,was |
R14588 |
T20481 |
T20482 |
arg1Of |
set,aside |
R14589 |
T20481 |
T20483 |
arg1Of |
set,for |
R1459 |
T2370 |
T2369 |
arg2Of |
in,or |
R14590 |
T20481 |
T20487 |
arg1Of |
set,and |
R14591 |
T20485 |
T20483 |
arg2Of |
control,for |
R14592 |
T20485 |
T20484 |
arg1Of |
control,input |
R14593 |
T20487 |
T20486 |
arg1Of |
and,"," |
R14594 |
T20487 |
T20496 |
arg1Of |
and,( |
R14595 |
T20490 |
T20488 |
arg1Of |
sample,the |
R14596 |
T20490 |
T20489 |
arg1Of |
sample,remaining |
R14597 |
T20490 |
T20491 |
arg1Of |
sample,was |
R14598 |
T20490 |
T20492 |
arg2Of |
sample,precleared |
R14599 |
T20492 |
T20487 |
arg2Of |
precleared,and |
R146 |
T354 |
T353 |
arg1Of |
region,pair |
R1460 |
T2229 |
T2224 |
arg2Of |
fashion,in |
R14600 |
T20492 |
T20491 |
arg2Of |
precleared,was |
R14601 |
T20492 |
T20493 |
arg1Of |
precleared,with |
R14602 |
T20495 |
T20493 |
arg2Of |
A-Sepharose,with |
R14603 |
T20495 |
T20494 |
arg1Of |
A-Sepharose,protein |
R14604 |
T20498 |
T20497 |
arg1Of |
Biosciences,Amersham |
R14605 |
T20498 |
T20499 |
arg1Of |
Biosciences,"," |
R14606 |
T20499 |
T20501 |
arg1Of |
",","," |
R14607 |
T20500 |
T20499 |
arg2Of |
Piscataway,"," |
R14608 |
T20501 |
T20504 |
arg1Of |
",","," |
R14609 |
T20503 |
T20501 |
arg2Of |
Jersey,"," |
R1461 |
T2372 |
T2370 |
arg2Of |
sequences,in |
R14610 |
T20503 |
T20502 |
arg1Of |
Jersey,New |
R14611 |
T20504 |
T20496 |
arg2Of |
",",( |
R14612 |
T20506 |
T20504 |
arg2Of |
States,"," |
R14613 |
T20506 |
T20505 |
arg1Of |
States,United |
R14614 |
T20507 |
T20496 |
arg3Of |
),( |
R14615 |
T20509 |
T20508 |
arg2Of |
preclearing,Following |
R14616 |
T20512 |
T20511 |
arg1Of |
samples,the |
R14617 |
T20512 |
T20513 |
arg1Of |
samples,were |
R14618 |
T20512 |
T20514 |
arg2Of |
samples,split |
R14619 |
T20514 |
T20513 |
arg2Of |
split,were |
R1462 |
T2372 |
T2371 |
arg1Of |
sequences,adjacent |
R14620 |
T20514 |
T20515 |
arg1Of |
split,into |
R14621 |
T20514 |
T20532 |
arg1Of |
split,and |
R14622 |
T20516 |
T20515 |
arg2Of |
thirds,into |
R14623 |
T20516 |
T20517 |
arg1Of |
thirds,: |
R14624 |
T20519 |
T20517 |
arg2Of |
sample,: |
R14625 |
T20519 |
T20518 |
arg1Of |
sample,one |
R14626 |
T20519 |
T20520 |
arg2Of |
sample,treated |
R14627 |
T20520 |
T20521 |
arg1Of |
treated,with |
R14628 |
T20522 |
T20521 |
arg2Of |
anti-Sox6,with |
R14629 |
T20522 |
T20523 |
arg1Of |
anti-Sox6,"," |
R1463 |
T2372 |
T2373 |
arg1Of |
sequences,[ |
R14630 |
T20525 |
T20523 |
arg2Of |
second,"," |
R14631 |
T20525 |
T20524 |
arg1Of |
second,a |
R14632 |
T20525 |
T20526 |
arg2Of |
second,treated |
R14633 |
T20526 |
T20527 |
arg1Of |
treated,with |
R14634 |
T20530 |
T20527 |
arg2Of |
IgG,with |
R14635 |
T20530 |
T20528 |
arg1Of |
IgG,normal |
R14636 |
T20530 |
T20529 |
arg1Of |
IgG,rabbit |
R14637 |
T20532 |
T20508 |
arg1Of |
and,Following |
R14638 |
T20532 |
T20510 |
arg1Of |
and,"," |
R14639 |
T20532 |
T20531 |
arg1Of |
and,"," |
R1464 |
T2229 |
T2225 |
arg1Of |
fashion,a |
R14640 |
T20535 |
T20533 |
arg1Of |
sample,the |
R14641 |
T20535 |
T20534 |
arg1Of |
sample,third |
R14642 |
T20535 |
T20536 |
arg1Of |
sample,without |
R14643 |
T20535 |
T20541 |
arg1Of |
sample,were |
R14644 |
T20535 |
T20542 |
arg2Of |
sample,used |
R14645 |
T20540 |
T20536 |
arg2Of |
two,without |
R14646 |
T20540 |
T20537 |
arg1Of |
two,Ab. |
R14647 |
T20540 |
T20538 |
arg1Of |
two,The |
R14648 |
T20540 |
T20539 |
arg1Of |
two,last |
R14649 |
T20542 |
T20532 |
arg2Of |
used,and |
R1465 |
T2374 |
T2373 |
arg2Of |
27,[ |
R14650 |
T20542 |
T20541 |
arg2Of |
used,were |
R14651 |
T20542 |
T20543 |
arg1Of |
used,as |
R14652 |
T20545 |
T20543 |
arg2Of |
controls,as |
R14653 |
T20545 |
T20544 |
arg1Of |
controls,negative |
R14654 |
T20548 |
T20546 |
arg1Of |
complexes,The |
R14655 |
T20548 |
T20547 |
arg1Of |
complexes,chromatin-antibody |
R14656 |
T20548 |
T20549 |
arg1Of |
complexes,were |
R14657 |
T20548 |
T20550 |
arg2Of |
complexes,eluted |
R14658 |
T20550 |
T20549 |
arg2Of |
eluted,were |
R14659 |
T20550 |
T20552 |
arg1Of |
eluted,and |
R1466 |
T2375 |
T2373 |
arg3Of |
],[ |
R14660 |
T20552 |
T20551 |
arg1Of |
and,"," |
R14661 |
T20556 |
T20553 |
arg1Of |
cross-links,the |
R14662 |
T20556 |
T20554 |
arg1Of |
cross-links,DNA |
R14663 |
T20556 |
T20555 |
arg1Of |
cross-links,protein |
R14664 |
T20556 |
T20557 |
arg1Of |
cross-links,were |
R14665 |
T20556 |
T20558 |
arg2Of |
cross-links,reversed |
R14666 |
T20558 |
T20552 |
arg2Of |
reversed,and |
R14667 |
T20558 |
T20557 |
arg2Of |
reversed,were |
R14668 |
T20558 |
T20559 |
arg1Of |
reversed,with |
R14669 |
T20558 |
T20563 |
arg1Of |
reversed,at |
R1467 |
T2229 |
T2226 |
arg1Of |
fashion,tissue- |
R14670 |
T20560 |
T20561 |
arg1Of |
5,M |
R14671 |
T20562 |
T20559 |
arg2Of |
NaCl,with |
R14672 |
T20562 |
T20560 |
arg1Of |
NaCl,5 |
R14673 |
T20565 |
T20563 |
arg2Of |
°C,at |
R14674 |
T20565 |
T20564 |
arg1Of |
°C,65 |
R14675 |
T20565 |
T20566 |
arg1Of |
°C,for |
R14676 |
T20568 |
T20566 |
arg2Of |
h,for |
R14677 |
T20568 |
T20567 |
arg1Of |
h,4 |
R14678 |
T20570 |
T20569 |
arg1Of |
DNA,Input |
R14679 |
T20570 |
T20571 |
arg1Of |
DNA,or |
R1468 |
T2229 |
T2228 |
arg1Of |
fashion,development-specific |
R14680 |
T20571 |
T20574 |
arg1Of |
or,was |
R14681 |
T20571 |
T20575 |
arg2Of |
or,used |
R14682 |
T20573 |
T20571 |
arg2Of |
DNA,or |
R14683 |
T20573 |
T20572 |
arg2Of |
DNA,immunoprecipitated |
R14684 |
T20575 |
T20574 |
arg2Of |
used,was |
R14685 |
T20575 |
T20576 |
arg1Of |
used,as |
R14686 |
T20578 |
T20576 |
arg2Of |
template,as |
R14687 |
T20578 |
T20577 |
arg1Of |
template,a |
R14688 |
T20578 |
T20579 |
arg1Of |
template,in |
R14689 |
T20582 |
T20579 |
arg2Of |
reaction,in |
R1469 |
T2231 |
T2230 |
arg2Of |
mice,In |
R14690 |
T20582 |
T20580 |
arg1Of |
reaction,the |
R14691 |
T20582 |
T20581 |
arg1Of |
reaction,PCR |
R14692 |
T20584 |
T20583 |
arg1Of |
amplification,PCR |
R14693 |
T20584 |
T20585 |
arg1Of |
amplification,of |
R14694 |
T20584 |
T20589 |
arg1Of |
amplification,was |
R14695 |
T20584 |
T20590 |
arg2Of |
amplification,performed |
R14696 |
T20584 |
T20592 |
arg1Of |
amplification,yielded |
R14697 |
T20588 |
T20585 |
arg2Of |
promoter,of |
R14698 |
T20588 |
T20586 |
arg1Of |
promoter,the |
R14699 |
T20588 |
T20587 |
arg1Of |
promoter,ɛy |
R147 |
T354 |
T355 |
arg1Of |
region,of |
R1470 |
T2379 |
T2380 |
arg1Of |
silencing,is |
R14700 |
T20590 |
T20589 |
arg2Of |
performed,was |
R14701 |
T20590 |
T20591 |
arg1Of |
performed,and |
R14702 |
T20591 |
T20596 |
arg1Of |
and,"," |
R14703 |
T20591 |
T20597 |
arg1Of |
and,corresponding |
R14704 |
T20592 |
T20591 |
arg2Of |
yielded,and |
R14705 |
T20595 |
T20592 |
arg2Of |
amplicon,yielded |
R14706 |
T20595 |
T20593 |
arg1Of |
amplicon,a |
R14707 |
T20595 |
T20594 |
arg1Of |
amplicon,172-bp |
R14708 |
T20598 |
T20597 |
arg2Of |
to,corresponding |
R14709 |
T20599 |
T20598 |
arg2Of |
nucleotides,to |
R1471 |
T2379 |
T2383 |
arg1Of |
silencing,autonomous |
R14710 |
T20599 |
T20600 |
arg1Of |
nucleotides,−31 |
R14711 |
T20600 |
T20601 |
arg1Of |
−31,to |
R14712 |
T20602 |
T20601 |
arg2Of |
+140,to |
R14713 |
T20602 |
T20603 |
arg1Of |
+140,of |
R14714 |
T20602 |
T20607 |
arg1Of |
+140,( |
R14715 |
T20606 |
T20603 |
arg2Of |
promoter,of |
R14716 |
T20606 |
T20604 |
arg1Of |
promoter,the |
R14717 |
T20606 |
T20605 |
arg1Of |
promoter,ɛy |
R14718 |
T20609 |
T20610 |
arg1Of |
MHB1688,"," |
R14719 |
T20610 |
T20613 |
arg1Of |
",",and |
R1472 |
T2380 |
T2377 |
arg2Of |
is,suggesting |
R14720 |
T20611 |
T20610 |
arg2Of |
5′CGAAGAATAAAAGGCCACCA3′,"," |
R14721 |
T20613 |
T20607 |
arg2Of |
and,( |
R14722 |
T20613 |
T20608 |
arg1Of |
and,primers |
R14723 |
T20613 |
T20612 |
arg1Of |
and,; |
R14724 |
T20613 |
T20615 |
arg1Of |
and,"," |
R14725 |
T20614 |
T20613 |
arg2Of |
MHB1689,and |
R14726 |
T20616 |
T20615 |
arg2Of |
5′GCTTCACCACCAACCTCTTC3′,"," |
R14727 |
T20617 |
T20607 |
arg3Of |
),( |
R14728 |
T20618 |
T20619 |
arg1Of |
PCR,was |
R14729 |
T20618 |
T20620 |
arg2Of |
PCR,performed |
R1473 |
T2380 |
T2378 |
arg1Of |
is,that |
R14730 |
T20620 |
T20619 |
arg2Of |
performed,was |
R14731 |
T20620 |
T20621 |
arg1Of |
performed,under |
R14732 |
T20620 |
T20625 |
arg1Of |
performed,: |
R14733 |
T20624 |
T20621 |
arg2Of |
conditions,under |
R14734 |
T20624 |
T20622 |
arg1Of |
conditions,the |
R14735 |
T20624 |
T20623 |
arg1Of |
conditions,following |
R14736 |
T20627 |
T20626 |
arg1Of |
°C,95 |
R14737 |
T20627 |
T20628 |
arg1Of |
°C,for |
R14738 |
T20627 |
T20631 |
arg1Of |
°C,followed |
R14739 |
T20627 |
T20655 |
arg1Of |
°C,ending |
R1474 |
T2380 |
T2381 |
arg1Of |
is,primarily |
R14740 |
T20630 |
T20628 |
arg2Of |
min,for |
R14741 |
T20630 |
T20629 |
arg1Of |
min,15 |
R14742 |
T20631 |
T20632 |
arg1Of |
followed,by |
R14743 |
T20631 |
T20635 |
arg1Of |
followed,at |
R14744 |
T20631 |
T20638 |
arg1Of |
followed,for |
R14745 |
T20631 |
T20641 |
arg1Of |
followed,"," |
R14746 |
T20631 |
T20651 |
arg1Of |
followed,for |
R14747 |
T20631 |
T20654 |
arg1Of |
followed,"," |
R14748 |
T20631 |
T20655 |
modOf |
followed,ending |
R14749 |
T20634 |
T20632 |
arg2Of |
cycles,by |
R1475 |
T2233 |
T2234 |
arg1Of |
erythropoiesis,originates |
R14750 |
T20634 |
T20633 |
arg1Of |
cycles,30 |
R14751 |
T20637 |
T20635 |
arg2Of |
°C,at |
R14752 |
T20637 |
T20636 |
arg1Of |
°C,95 |
R14753 |
T20640 |
T20638 |
arg2Of |
s,for |
R14754 |
T20640 |
T20639 |
arg1Of |
s,30 |
R14755 |
T20643 |
T20642 |
arg1Of |
°C,60 |
R14756 |
T20643 |
T20644 |
arg1Of |
°C,for |
R14757 |
T20643 |
T20648 |
arg1Of |
°C,and |
R14758 |
T20646 |
T20644 |
arg2Of |
s,for |
R14759 |
T20646 |
T20645 |
arg1Of |
s,30 |
R1476 |
T2383 |
T2380 |
arg2Of |
autonomous,is |
R14760 |
T20648 |
T20631 |
arg2Of |
and,followed |
R14761 |
T20648 |
T20647 |
arg1Of |
and,"," |
R14762 |
T20650 |
T20648 |
arg2Of |
°C,and |
R14763 |
T20650 |
T20649 |
arg1Of |
°C,72 |
R14764 |
T20653 |
T20651 |
arg2Of |
s,for |
R14765 |
T20653 |
T20652 |
arg1Of |
s,45 |
R14766 |
T20655 |
T20656 |
arg1Of |
ending,with |
R14767 |
T20655 |
T20663 |
arg1Of |
ending,for |
R14768 |
T20659 |
T20656 |
arg2Of |
extension,with |
R14769 |
T20659 |
T20657 |
arg1Of |
extension,a |
R1477 |
T2234 |
T2230 |
arg1Of |
originates,In |
R14770 |
T20659 |
T20658 |
arg1Of |
extension,final |
R14771 |
T20659 |
T20660 |
arg1Of |
extension,at |
R14772 |
T20662 |
T20660 |
arg2Of |
°C,at |
R14773 |
T20662 |
T20661 |
arg1Of |
°C,72 |
R14774 |
T20665 |
T20663 |
arg2Of |
min,for |
R14775 |
T20665 |
T20664 |
arg1Of |
min,5 |
R1478 |
T2383 |
T2382 |
arg1Of |
autonomous,gene |
R1479 |
T2234 |
T2232 |
arg1Of |
originates,"," |
R148 |
T359 |
T355 |
arg2Of |
promoter,of |
R1480 |
T2234 |
T2235 |
arg1Of |
originates,in |
R1481 |
T2239 |
T2235 |
arg2Of |
sac,in |
R1482 |
T2387 |
T2384 |
arg2Of |
analyses,Using |
R1483 |
T2387 |
T2385 |
arg1Of |
analyses,promoter |
R1484 |
T2387 |
T2386 |
arg1Of |
analyses,deletion |
R1485 |
T2387 |
T2388 |
arg1Of |
analyses,in |
R1486 |
T2391 |
T2389 |
arg1Of |
models,transgenic |
R1487 |
T2391 |
T2390 |
arg1Of |
models,mouse |
R1488 |
T2391 |
T2392 |
arg1Of |
models,and |
R1489 |
T2392 |
T2388 |
arg2Of |
and,in |
R149 |
T359 |
T356 |
arg1Of |
promoter,the |
R1490 |
T2239 |
T2236 |
arg1Of |
sac,the |
R1491 |
T2395 |
T2392 |
arg2Of |
assays,and |
R1492 |
T2395 |
T2393 |
arg1Of |
assays,cell |
R1493 |
T2395 |
T2394 |
arg1Of |
assays,transfection |
R1494 |
T2239 |
T2237 |
arg1Of |
sac,embryonic |
R1495 |
T2239 |
T2238 |
arg1Of |
sac,yolk |
R1496 |
T2239 |
T2240 |
arg1Of |
sac,where |
R1497 |
T2399 |
T2384 |
arg1Of |
elements,Using |
R1498 |
T2399 |
T2397 |
arg1Of |
elements,multiple |
R1499 |
T2399 |
T2398 |
arg1Of |
elements,DNA |
R150 |
T359 |
T357 |
arg1Of |
promoter,ɛy |
R1500 |
T2399 |
T2400 |
arg1Of |
elements,important |
R1501 |
T2399 |
T2405 |
arg1Of |
elements,have |
R1502 |
T2399 |
T2406 |
arg1Of |
elements,been |
R1503 |
T2399 |
T2408 |
arg2Of |
elements,identified |
R1504 |
T2400 |
T2401 |
arg1Of |
important,to |
R1505 |
T2243 |
T2241 |
arg1Of |
cells,primitive |
R1506 |
T2404 |
T2401 |
arg2Of |
process,to |
R1507 |
T2404 |
T2402 |
arg1Of |
process,the |
R1508 |
T2404 |
T2403 |
arg1Of |
process,silencing |
R1509 |
T2408 |
T2384 |
modOf |
identified,Using |
R151 |
T359 |
T358 |
arg1Of |
promoter,proximal |
R1510 |
T2408 |
T2396 |
arg1Of |
identified,"," |
R1511 |
T2408 |
T2405 |
arg2Of |
identified,have |
R1512 |
T2408 |
T2406 |
arg2Of |
identified,been |
R1513 |
T2408 |
T2407 |
arg1Of |
identified,previously |
R1514 |
T2408 |
T2409 |
arg1Of |
identified,in |
R1515 |
T2408 |
T2419 |
arg1Of |
identified,[ |
R1516 |
T2412 |
T2413 |
arg1Of |
proximal,and |
R1517 |
T2243 |
T2242 |
arg1Of |
cells,erythroid |
R1518 |
T2243 |
T2244 |
arg1Of |
cells,express |
R1519 |
T2244 |
T2240 |
arg2Of |
express,where |
R152 |
T359 |
T360 |
arg1Of |
promoter,that |
R1520 |
T2415 |
T2413 |
arg2Of |
distal,and |
R1521 |
T2415 |
T2414 |
arg1Of |
distal,the |
R1522 |
T2244 |
T2249 |
arg1Of |
express,[ |
R1523 |
T2418 |
T2409 |
arg2Of |
promoter,in |
R1524 |
T2418 |
T2410 |
arg1Of |
promoter,both |
R1525 |
T2418 |
T2411 |
arg1Of |
promoter,the |
R1526 |
T2418 |
T2412 |
arg1Of |
promoter,proximal |
R1527 |
T2418 |
T2415 |
arg1Of |
promoter,distal |
R1528 |
T2418 |
T2416 |
arg1Of |
promoter,ɛ |
R1529 |
T2418 |
T2417 |
arg1Of |
promoter,gene |
R153 |
T359 |
T361 |
arg1Of |
promoter,is |
R1530 |
T2420 |
T2419 |
arg2Of |
27,[ |
R1531 |
T2245 |
T2246 |
arg1Of |
ɛy,and |
R1532 |
T2421 |
T2419 |
arg3Of |
],[ |
R1533 |
T2247 |
T2246 |
arg2Of |
βh-1,and |
R1534 |
T2425 |
T2422 |
arg1Of |
factors,Their |
R1535 |
T2425 |
T2423 |
arg1Of |
factors,corresponding |
R1536 |
T2425 |
T2424 |
arg1Of |
factors,transcription |
R1537 |
T2425 |
T2426 |
arg1Of |
factors,"," |
R1538 |
T2425 |
T2428 |
arg1Of |
factors,as |
R1539 |
T2248 |
T2244 |
arg2Of |
globins,express |
R154 |
T359 |
T362 |
arg1Of |
promoter,critical |
R1540 |
T2425 |
T2437 |
arg1Of |
factors,have |
R1541 |
T2425 |
T2438 |
arg1Of |
factors,been |
R1542 |
T2425 |
T2439 |
arg2Of |
factors,identified |
R1543 |
T2425 |
T2441 |
arg2Of |
factors,shown |
R1544 |
T2425 |
T2444 |
arg1Of |
factors,bind |
R1545 |
T2425 |
T2457 |
arg1Of |
factors,regulate |
R1546 |
T2248 |
T2245 |
arg1Of |
globins,ɛy |
R1547 |
T2248 |
T2247 |
arg1Of |
globins,βh-1 |
R1548 |
T2428 |
T2427 |
arg1Of |
as,such |
R1549 |
T2250 |
T2249 |
arg2Of |
22,[ |
R155 |
T362 |
T361 |
arg2Of |
critical,is |
R1550 |
T2429 |
T2430 |
arg1Of |
GATA-1,"," |
R1551 |
T2430 |
T2432 |
arg1Of |
",","," |
R1552 |
T2431 |
T2430 |
arg2Of |
YY-1,"," |
R1553 |
T2432 |
T2435 |
arg1Of |
",",and |
R1554 |
T2251 |
T2249 |
arg3Of |
],[ |
R1555 |
T2433 |
T2432 |
arg2Of |
COUP-TF,"," |
R1556 |
T2435 |
T2428 |
arg2Of |
and,as |
R1557 |
T2435 |
T2434 |
arg1Of |
and,"," |
R1558 |
T2436 |
T2435 |
arg2Of |
DRED,and |
R1559 |
T2256 |
T2252 |
arg2Of |
coitus,At |
R156 |
T362 |
T363 |
arg1Of |
critical,for |
R1560 |
T2439 |
T2440 |
arg1Of |
identified,and |
R1561 |
T2440 |
T2437 |
arg2Of |
and,have |
R1562 |
T2440 |
T2438 |
arg2Of |
and,been |
R1563 |
T2441 |
T2440 |
arg2Of |
shown,and |
R1564 |
T2444 |
T2441 |
arg3Of |
bind,shown |
R1565 |
T2444 |
T2442 |
arg1Of |
bind,to |
R1566 |
T2444 |
T2443 |
arg1Of |
bind,directly |
R1567 |
T2444 |
T2445 |
arg1Of |
bind,to |
R1568 |
T2444 |
T2449 |
arg1Of |
bind,( |
R1569 |
T2444 |
T2456 |
modOf |
bind,to |
R157 |
T366 |
T363 |
arg2Of |
repression,for |
R1570 |
T2444 |
T2459 |
modOf |
bind,silencing |
R1571 |
T2444 |
T2460 |
arg1Of |
bind,[ |
R1572 |
T2256 |
T2253 |
arg1Of |
coitus,11.5 |
R1573 |
T2448 |
T2445 |
arg2Of |
elements,to |
R1574 |
T2448 |
T2446 |
arg1Of |
elements,these |
R1575 |
T2448 |
T2447 |
arg1Of |
elements,DNA |
R1576 |
T2256 |
T2254 |
arg1Of |
coitus,d |
R1577 |
T2450 |
T2449 |
arg2Of |
as,( |
R1578 |
T2256 |
T2255 |
arg1Of |
coitus,post |
R1579 |
T2451 |
T2450 |
arg2Of |
part,as |
R158 |
T366 |
T364 |
arg1Of |
repression,Sox6 |
R1580 |
T2451 |
T2452 |
arg1Of |
part,of |
R1581 |
T2256 |
T2257 |
arg1Of |
coitus,( |
R1582 |
T2258 |
T2257 |
arg2Of |
dpc,( |
R1583 |
T2454 |
T2452 |
arg2Of |
complexes,of |
R1584 |
T2454 |
T2453 |
arg1Of |
complexes,protein |
R1585 |
T2455 |
T2449 |
arg3Of |
),( |
R1586 |
T2457 |
T2456 |
arg1Of |
regulate,to |
R1587 |
T2457 |
T2458 |
arg1Of |
regulate,ɛ |
R1588 |
T2259 |
T2257 |
arg3Of |
),( |
R1589 |
T2262 |
T2261 |
arg1Of |
shifts,erythropoiesis |
R159 |
T366 |
T365 |
arg2Of |
repression,mediated |
R1590 |
T2461 |
T2460 |
arg2Of |
27,[ |
R1591 |
T2462 |
T2460 |
arg3Of |
],[ |
R1592 |
T2262 |
T2263 |
arg1Of |
shifts,to |
R1593 |
T2262 |
T2267 |
arg1Of |
shifts,where |
R1594 |
T2262 |
T2276 |
arg1Of |
shifts,β |
R1595 |
T2266 |
T2263 |
arg2Of |
liver,to |
R1596 |
T2266 |
T2264 |
arg1Of |
liver,the |
R1597 |
T2266 |
T2265 |
arg1Of |
liver,fetal |
R1598 |
T2465 |
T2466 |
arg1Of |
it,appears |
R1599 |
T2561 |
T2560 |
arg2Of |
maturation,delayed |
R160 |
T370 |
T367 |
arg1Of |
assay,Electrophoretic |
R1600 |
T2466 |
T2463 |
arg1Of |
appears,Thus |
R1601 |
T2466 |
T2464 |
arg1Of |
appears,"," |
R1602 |
T2469 |
T2468 |
arg1Of |
silencing,the |
R1603 |
T2469 |
T2470 |
arg1Of |
silencing,of |
R1604 |
T2469 |
T2474 |
arg1Of |
silencing,involves |
R1605 |
T2473 |
T2470 |
arg2Of |
gene,of |
R1606 |
T2473 |
T2471 |
arg1Of |
gene,the |
R1607 |
T2473 |
T2472 |
arg1Of |
gene,ɛ |
R1608 |
T2474 |
T2466 |
arg2Of |
involves,appears |
R1609 |
T2474 |
T2467 |
arg1Of |
involves,that |
R161 |
T370 |
T368 |
arg1Of |
assay,mobility |
R1610 |
T2477 |
T2474 |
arg2Of |
network,involves |
R1611 |
T2477 |
T2475 |
arg1Of |
network,a |
R1612 |
T2477 |
T2476 |
arg1Of |
network,complicated |
R1613 |
T2477 |
T2478 |
arg1Of |
network,of |
R1614 |
T2561 |
T2562 |
arg1Of |
maturation,of |
R1615 |
T2561 |
T2564 |
arg1Of |
maturation,( |
R1616 |
T2561 |
T2577 |
arg1Of |
maturation,and |
R1617 |
T2481 |
T2479 |
arg1Of |
elements,multiple |
R1618 |
T2481 |
T2480 |
arg1Of |
elements,cis |
R1619 |
T2481 |
T2482 |
arg1Of |
elements,and |
R162 |
T370 |
T369 |
arg1Of |
assay,shift |
R1620 |
T2563 |
T2562 |
arg2Of |
erythrocytes,of |
R1621 |
T2482 |
T2478 |
arg2Of |
and,of |
R1622 |
T2484 |
T2482 |
arg2Of |
proteins,and |
R1623 |
T2484 |
T2483 |
arg1Of |
proteins,transacting |
R1624 |
T2486 |
T2487 |
arg1Of |
addition,to |
R1625 |
T2565 |
T2564 |
arg2Of |
that,( |
R1626 |
T2486 |
T2503 |
arg1Of |
addition,"," |
R1627 |
T2565 |
T2567 |
arg1Of |
that,enucleate |
R1628 |
T2488 |
T2487 |
arg2Of |
playing,to |
R1629 |
T2488 |
T2492 |
arg1Of |
playing,in |
R163 |
T370 |
T371 |
arg1Of |
assay,( |
R1630 |
T2567 |
T2566 |
arg1Of |
enucleate,normally |
R1631 |
T2491 |
T2488 |
arg2Of |
role,playing |
R1632 |
T2491 |
T2489 |
arg1Of |
role,an |
R1633 |
T2491 |
T2490 |
arg1Of |
role,important |
R1634 |
T2567 |
T2569 |
arg1Of |
enucleate,to |
R1635 |
T2494 |
T2492 |
arg2Of |
development,in |
R1636 |
T2494 |
T2493 |
arg1Of |
development,the |
R1637 |
T2494 |
T2495 |
arg1Of |
development,of |
R1638 |
T2569 |
T2568 |
arg1Of |
to,prior |
R1639 |
T2570 |
T2569 |
arg2Of |
entering,to |
R164 |
T370 |
T374 |
arg1Of |
assay,and |
R1640 |
T2499 |
T2495 |
arg2Of |
system,of |
R1641 |
T2499 |
T2496 |
arg1Of |
system,the |
R1642 |
T2499 |
T2497 |
arg1Of |
system,central |
R1643 |
T2499 |
T2498 |
arg1Of |
system,nervous |
R1644 |
T2499 |
T2500 |
arg1Of |
system,[ |
R1645 |
T2501 |
T2500 |
arg2Of |
8–11,[ |
R1646 |
T2572 |
T2570 |
arg2Of |
bloodstream,entering |
R1647 |
T2502 |
T2500 |
arg3Of |
],[ |
R1648 |
T2503 |
T2509 |
arg1Of |
",",and |
R1649 |
T2504 |
T2503 |
arg2Of |
cartilage,"," |
R165 |
T372 |
T371 |
arg2Of |
EMSA,( |
R1650 |
T2504 |
T2505 |
arg1Of |
cartilage,[ |
R1651 |
T2572 |
T2571 |
arg1Of |
bloodstream,the |
R1652 |
T2506 |
T2505 |
arg2Of |
"6,12,13",[ |
R1653 |
T2507 |
T2505 |
arg3Of |
],[ |
R1654 |
T2572 |
T2573 |
arg1Of |
bloodstream,[ |
R1655 |
T2574 |
T2573 |
arg2Of |
27,[ |
R1656 |
T2509 |
T2485 |
arg2Of |
and,In |
R1657 |
T2509 |
T2508 |
arg1Of |
and,"," |
R1658 |
T2510 |
T2509 |
arg2Of |
muscle,and |
R1659 |
T2510 |
T2511 |
arg1Of |
muscle,[ |
R166 |
T373 |
T371 |
arg3Of |
),( |
R1660 |
T2512 |
T2511 |
arg2Of |
"14,15",[ |
R1661 |
T2513 |
T2511 |
arg3Of |
],[ |
R1662 |
T2515 |
T2516 |
arg1Of |
it,was |
R1663 |
T2515 |
T2517 |
arg2Of |
it,shown |
R1664 |
T2575 |
T2573 |
arg3Of |
],[ |
R1665 |
T2517 |
T2485 |
arg1Of |
shown,In |
R1666 |
T2517 |
T2514 |
arg1Of |
shown,"," |
R1667 |
T2517 |
T2516 |
arg2Of |
shown,was |
R1668 |
T2519 |
T2520 |
arg1Of |
Sox6,is |
R1669 |
T2519 |
T2521 |
arg2Of |
Sox6,upregulated |
R167 |
T374 |
T381 |
arg1Of |
and,demonstrate |
R1670 |
T2576 |
T2564 |
arg3Of |
),( |
R1671 |
T2521 |
T2517 |
arg3Of |
upregulated,shown |
R1672 |
T2521 |
T2518 |
arg1Of |
upregulated,that |
R1673 |
T2521 |
T2520 |
arg2Of |
upregulated,is |
R1674 |
T2521 |
T2522 |
arg1Of |
upregulated,in |
R1675 |
T2521 |
T2530 |
arg1Of |
upregulated,compared |
R1676 |
T2521 |
T2540 |
arg1Of |
upregulated,[ |
R1677 |
T2577 |
T2559 |
arg2Of |
and,include |
R1678 |
T2526 |
T2522 |
arg2Of |
cells,in |
R1679 |
T2526 |
T2523 |
arg1Of |
cells,long-term |
R168 |
T378 |
T377 |
arg2Of |
ChIP,( |
R1680 |
T2526 |
T2524 |
arg1Of |
cells,hematopoiesis |
R1681 |
T2526 |
T2525 |
arg1Of |
cells,stem |
R1682 |
T2526 |
T2527 |
arg1Of |
cells,( |
R1683 |
T2528 |
T2527 |
arg2Of |
LT-HSC,( |
R1684 |
T2579 |
T2577 |
arg2Of |
expression,and |
R1685 |
T2529 |
T2527 |
arg3Of |
),( |
R1686 |
T2531 |
T2530 |
arg2Of |
with,compared |
R1687 |
T2579 |
T2578 |
arg1Of |
expression,higher |
R1688 |
T2579 |
T2580 |
arg1Of |
expression,of |
R1689 |
T2533 |
T2531 |
arg2Of |
progenitors,with |
R169 |
T379 |
T377 |
arg3Of |
),( |
R1690 |
T2533 |
T2532 |
arg1Of |
progenitors,multipotent |
R1691 |
T2533 |
T2534 |
arg1Of |
progenitors,of |
R1692 |
T2583 |
T2580 |
arg2Of |
genes,of |
R1693 |
T2539 |
T2534 |
arg2Of |
lineage,of |
R1694 |
T2539 |
T2535 |
arg1Of |
lineage,adult |
R1695 |
T2539 |
T2536 |
arg1Of |
lineage,mouse |
R1696 |
T2539 |
T2537 |
arg1Of |
lineage,bone |
R1697 |
T2539 |
T2538 |
arg1Of |
lineage,marrow |
R1698 |
T2583 |
T2581 |
arg1Of |
genes,embryonic |
R1699 |
T2541 |
T2540 |
arg2Of |
28,[ |
R170 |
T380 |
T374 |
arg2Of |
assays,and |
R1700 |
T2542 |
T2540 |
arg3Of |
],[ |
R1701 |
T2583 |
T2582 |
arg1Of |
genes,globin |
R1702 |
T2586 |
T2585 |
arg1Of |
extreme,most |
R1703 |
T2545 |
T2543 |
arg2Of |
study,In |
R1704 |
T2545 |
T2544 |
arg1Of |
study,this |
R1705 |
T2547 |
T2548 |
arg2Of |
we,describe |
R1706 |
T2548 |
T2543 |
arg1Of |
describe,In |
R1707 |
T2548 |
T2546 |
arg1Of |
describe,"," |
R1708 |
T2550 |
T2552 |
arg1Of |
Sox6,exerts |
R1709 |
T2587 |
T2584 |
arg1Of |
effect,The |
R171 |
T380 |
T375 |
arg1Of |
assays,chromatin |
R1710 |
T2552 |
T2548 |
arg1Of |
exerts,describe |
R1711 |
T2552 |
T2549 |
arg1Of |
exerts,that |
R1712 |
T2552 |
T2551 |
arg1Of |
exerts,also |
R1713 |
T2552 |
T2555 |
arg1Of |
exerts,on |
R1714 |
T2554 |
T2552 |
arg2Of |
effects,exerts |
R1715 |
T2554 |
T2553 |
arg1Of |
effects,pleiotropic |
R1716 |
T2556 |
T2555 |
arg2Of |
erythropoiesis,on |
R1717 |
T2587 |
T2586 |
arg1Of |
effect,extreme |
R1718 |
T2587 |
T2588 |
arg1Of |
effect,is |
R1719 |
T2558 |
T2557 |
arg1Of |
effects,These |
R172 |
T380 |
T376 |
arg1Of |
assays,immunoprecipitation |
R1720 |
T2558 |
T2559 |
arg1Of |
effects,include |
R1721 |
T2590 |
T2588 |
arg2Of |
persistence,is |
R1722 |
T2590 |
T2589 |
arg1Of |
persistence,the |
R1723 |
T2590 |
T2591 |
arg1Of |
persistence,of |
R1724 |
T2593 |
T2591 |
arg2Of |
expression,of |
R1725 |
T2657 |
T2653 |
arg2Of |
pattern,"," |
R1726 |
T2657 |
T2654 |
arg1Of |
pattern,the |
R1727 |
T2657 |
T2655 |
arg1Of |
pattern,opposite |
R1728 |
T2657 |
T2656 |
arg1Of |
pattern,expression |
R1729 |
T2657 |
T2658 |
arg1Of |
pattern,of |
R173 |
T380 |
T377 |
arg1Of |
assays,( |
R1730 |
T2660 |
T2658 |
arg2Of |
globin,of |
R1731 |
T2660 |
T2659 |
arg1Of |
globin,ɛy |
R1732 |
T2593 |
T2592 |
arg1Of |
expression,high |
R1733 |
T2661 |
T2662 |
arg1Of |
In,the |
R1734 |
T2661 |
T2664 |
arg1Of |
In,of |
R1735 |
T2593 |
T2594 |
arg1Of |
expression,of |
R1736 |
T2663 |
T2661 |
arg2Of |
absence,In |
R1737 |
T2599 |
T2594 |
arg2Of |
gene,of |
R1738 |
T2665 |
T2661 |
arg3Of |
Sox6,In |
R1739 |
T2668 |
T2667 |
arg1Of |
globin,ɛy |
R174 |
T383 |
T384 |
arg1Of |
Sox6,acts |
R1740 |
T2668 |
T2669 |
arg1Of |
globin,is |
R1741 |
T2668 |
T2671 |
arg2Of |
globin,expressed |
R1742 |
T2671 |
T2661 |
arg1Of |
expressed,In |
R1743 |
T2599 |
T2595 |
arg1Of |
gene,the |
R1744 |
T2671 |
T2666 |
arg1Of |
expressed,"," |
R1745 |
T2671 |
T2669 |
arg2Of |
expressed,is |
R1746 |
T2671 |
T2670 |
arg1Of |
expressed,ectopically |
R1747 |
T2671 |
T2672 |
arg1Of |
expressed,in |
R1748 |
T2671 |
T2676 |
arg1Of |
expressed,"," |
R1749 |
T2671 |
T2677 |
modOf |
expressed,demonstrating |
R175 |
T384 |
T381 |
arg2Of |
acts,demonstrate |
R1750 |
T2599 |
T2596 |
arg1Of |
gene,embryonic |
R1751 |
T2599 |
T2597 |
arg1Of |
gene,ɛy |
R1752 |
T2675 |
T2672 |
arg2Of |
liver,in |
R1753 |
T2675 |
T2673 |
arg1Of |
liver,the |
R1754 |
T2675 |
T2674 |
arg1Of |
liver,fetal |
R1755 |
T2599 |
T2598 |
arg1Of |
gene,globin |
R1756 |
T2601 |
T2602 |
arg1Of |
we,describe |
R1757 |
T2680 |
T2677 |
arg2Of |
functions,demonstrating |
R1758 |
T2680 |
T2678 |
arg1Of |
functions,that |
R1759 |
T2680 |
T2679 |
arg1Of |
functions,Sox6 |
R176 |
T384 |
T382 |
arg1Of |
acts,that |
R1760 |
T2680 |
T2681 |
arg1Of |
functions,in |
R1761 |
T2683 |
T2681 |
arg2Of |
erythropoiesis,in |
R1762 |
T2683 |
T2682 |
arg1Of |
erythropoiesis,definitive |
R1763 |
T2601 |
T2604 |
arg1Of |
we,characterize |
R1764 |
T2602 |
T2603 |
arg1Of |
describe,and |
R1765 |
T2603 |
T2600 |
arg1Of |
and,Here |
R1766 |
T2604 |
T2603 |
arg2Of |
characterize,and |
R1767 |
T2606 |
T2602 |
arg2Of |
effects,describe |
R1768 |
T2606 |
T2604 |
arg2Of |
effects,characterize |
R1769 |
T2606 |
T2605 |
arg1Of |
effects,the |
R177 |
T384 |
T385 |
arg1Of |
acts,as |
R1770 |
T2606 |
T2607 |
arg1Of |
effects,of |
R1771 |
T2606 |
T2609 |
arg1Of |
effects,on |
R1772 |
T2608 |
T2607 |
arg2Of |
Sox6,of |
R1773 |
T2613 |
T2609 |
arg2Of |
gene,on |
R1776 |
T2613 |
T2610 |
arg1Of |
gene,the |
R1777 |
T2613 |
T2611 |
arg1Of |
gene,ɛy |
R1778 |
T2613 |
T2612 |
arg1Of |
gene,globin |
R1779 |
T2614 |
T2615 |
arg1Of |
We,show |
R178 |
T384 |
T388 |
arg1Of |
acts,by |
R1781 |
T2617 |
T2618 |
arg1Of |
Sox6,binds |
R1783 |
T2617 |
T2627 |
arg1Of |
Sox6,represses |
R1784 |
T2618 |
T2619 |
arg1Of |
binds,to |
R1785 |
T2618 |
T2626 |
arg1Of |
binds,and |
R1787 |
T2622 |
T2619 |
arg2Of |
promoter,to |
R1789 |
T2622 |
T2620 |
arg1Of |
promoter,the |
R179 |
T387 |
T385 |
arg2Of |
repressor,as |
R1790 |
T2622 |
T2621 |
arg1Of |
promoter,proximal |
R1791 |
T2622 |
T2623 |
arg1Of |
promoter,of |
R1792 |
T2625 |
T2623 |
arg2Of |
globin,of |
R1795 |
T2625 |
T2624 |
arg1Of |
globin,ɛy |
R1796 |
T2626 |
T2615 |
arg2Of |
and,show |
R1797 |
T2626 |
T2616 |
arg1Of |
and,that |
R1798 |
T2627 |
T2626 |
arg2Of |
represses,and |
R1799 |
T2629 |
T2627 |
arg2Of |
transcription,represses |
R180 |
T387 |
T386 |
arg1Of |
repressor,a |
R1800 |
T2629 |
T2628 |
arg1Of |
transcription,its |
R1801 |
T2631 |
T2632 |
arg1Of |
wild-type,( |
R1803 |
T2633 |
T2632 |
arg2Of |
WT,( |
R1804 |
T2634 |
T2632 |
arg3Of |
),( |
R1806 |
T2635 |
T2630 |
arg2Of |
mice,In |
R1807 |
T2635 |
T2631 |
arg1Of |
mice,wild-type |
R181 |
T390 |
T388 |
arg2Of |
binding,by |
R1810 |
T2637 |
T2638 |
arg1Of |
Sox6,is |
R1812 |
T2637 |
T2640 |
arg2Of |
Sox6,expressed |
R1813 |
T2637 |
T2648 |
arg1Of |
Sox6,is |
R1814 |
T2637 |
T2649 |
arg2Of |
Sox6,expressed |
R1815 |
T2640 |
T2638 |
arg2Of |
expressed,is |
R1817 |
T2640 |
T2639 |
arg1Of |
expressed,not |
R1818 |
T2640 |
T2641 |
arg1Of |
expressed,in |
R1819 |
T2640 |
T2647 |
arg1Of |
expressed,but |
R182 |
T390 |
T389 |
arg1Of |
binding,directly |
R1821 |
T2645 |
T2641 |
arg2Of |
islands,in |
R1823 |
T2645 |
T2642 |
arg1Of |
islands,yolk |
R1824 |
T2645 |
T2643 |
arg1Of |
islands,sac |
R1825 |
T2645 |
T2644 |
arg1Of |
islands,blood |
R1827 |
T2647 |
T2630 |
arg1Of |
but,In |
R1829 |
T2647 |
T2636 |
arg1Of |
but,"," |
R183 |
T390 |
T391 |
arg1Of |
binding,to |
R1830 |
T2647 |
T2646 |
arg1Of |
but,"," |
R1831 |
T2649 |
T2647 |
arg2Of |
expressed,but |
R1833 |
T2649 |
T2648 |
arg2Of |
expressed,is |
R1834 |
T2649 |
T2650 |
arg1Of |
expressed,in |
R1835 |
T2652 |
T2650 |
arg2Of |
liver,in |
R1838 |
T2652 |
T2651 |
arg1Of |
liver,fetal |
R1839 |
T2652 |
T2653 |
arg1Of |
liver,"," |
R184 |
T394 |
T391 |
arg2Of |
promoter,to |
R185 |
T394 |
T392 |
arg1Of |
promoter,the |
R186 |
T394 |
T393 |
arg1Of |
promoter,ɛy |
R187 |
T397 |
T395 |
arg1Of |
expression,The |
R188 |
T397 |
T396 |
arg1Of |
expression,normal |
R189 |
T397 |
T398 |
arg1Of |
expression,of |
R190 |
T397 |
T400 |
arg1Of |
expression,in |
R191 |
T397 |
T404 |
arg1Of |
expression,and |
R192 |
T399 |
T398 |
arg2Of |
Sox6,of |
R193 |
T403 |
T400 |
arg2Of |
liver,in |
R194 |
T403 |
T401 |
arg1Of |
liver,wild-type |
R195 |
T403 |
T402 |
arg1Of |
liver,fetal |
R196 |
T404 |
T415 |
arg1Of |
and,demonstrate |
R197 |
T407 |
T404 |
arg2Of |
expression,and |
R198 |
T407 |
T405 |
arg1Of |
expression,the |
R199 |
T407 |
T406 |
arg1Of |
expression,ectopic |
R200 |
T407 |
T408 |
arg1Of |
expression,of |
R201 |
T407 |
T410 |
arg1Of |
expression,in |
R202 |
T409 |
T408 |
arg2Of |
ɛy,of |
R203 |
T414 |
T410 |
arg2Of |
liver,in |
R204 |
T414 |
T411 |
arg1Of |
liver,p100H |
R205 |
T414 |
T412 |
arg1Of |
liver,homozygous |
R206 |
T414 |
T413 |
arg1Of |
liver,fetal |
R207 |
T415 |
T419 |
arg1Of |
demonstrate,in |
R208 |
T418 |
T415 |
arg2Of |
functions,demonstrate |
R209 |
T418 |
T416 |
arg1Of |
functions,that |
R210 |
T418 |
T417 |
arg1Of |
functions,Sox6 |
R211 |
T421 |
T419 |
arg2Of |
erythropoiesis,in |
R212 |
T421 |
T420 |
arg1Of |
erythropoiesis,definitive |
R213 |
T424 |
T422 |
arg1Of |
study,The |
R214 |
T424 |
T423 |
arg1Of |
study,present |
R215 |
T424 |
T425 |
arg1Of |
study,shows |
R216 |
T427 |
T428 |
arg1Of |
Sox6,is |
R217 |
T427 |
T429 |
arg2Of |
Sox6,required |
R218 |
T427 |
T439 |
arg1Of |
Sox6,suggests |
R219 |
T429 |
T428 |
arg2Of |
required,is |
R220 |
T429 |
T430 |
arg1Of |
required,for |
R221 |
T429 |
T438 |
arg1Of |
required,and |
R222 |
T431 |
T430 |
arg2Of |
silencing,for |
R223 |
T431 |
T432 |
arg1Of |
silencing,of |
R224 |
T431 |
T435 |
arg1Of |
silencing,in |
R225 |
T434 |
T432 |
arg2Of |
globin,of |
R226 |
T434 |
T433 |
arg1Of |
globin,ɛy |
R227 |
T437 |
T435 |
arg2Of |
erythropoiesis,in |
R228 |
T437 |
T436 |
arg1Of |
erythropoiesis,definitive |
R229 |
T438 |
T425 |
arg2Of |
and,shows |
R230 |
T438 |
T426 |
arg1Of |
and,that |
R231 |
T439 |
T438 |
arg2Of |
suggests,and |
R232 |
T441 |
T439 |
arg2Of |
role,suggests |
R233 |
T441 |
T440 |
arg1Of |
role,a |
R234 |
T441 |
T442 |
arg1Of |
role,for |
R235 |
T441 |
T444 |
arg1Of |
role,in |
R236 |
T443 |
T442 |
arg2Of |
Sox6,for |
R237 |
T447 |
T444 |
arg2Of |
maturation,in |
R238 |
T447 |
T445 |
arg1Of |
maturation,erythroid |
R239 |
T447 |
T446 |
arg1Of |
maturation,cell |
R240 |
T451 |
T450 |
arg1Of |
regulation,Sox6 |
R241 |
T451 |
T452 |
arg1Of |
regulation,of |
R242 |
T451 |
T455 |
arg1Of |
regulation,might |
R243 |
T451 |
T456 |
arg1Of |
regulation,provide |
R244 |
T454 |
T452 |
arg2Of |
globin,of |
R245 |
T454 |
T453 |
arg1Of |
globin,ɛy |
R246 |
T456 |
T448 |
arg1Of |
provide,Thus |
R247 |
T456 |
T449 |
arg1Of |
provide,"," |
R248 |
T456 |
T455 |
arg2Of |
provide,might |
R249 |
T460 |
T456 |
arg2Of |
target,provide |
R250 |
T460 |
T457 |
arg1Of |
target,a |
R251 |
T460 |
T458 |
arg1Of |
target,novel |
R252 |
T460 |
T459 |
arg1Of |
target,therapeutical |
R253 |
T460 |
T461 |
arg1Of |
target,in |
R254 |
T463 |
T461 |
arg2Of |
treatment,in |
R255 |
T463 |
T462 |
arg1Of |
treatment,the |
R256 |
T463 |
T464 |
arg1Of |
treatment,of |
R257 |
T465 |
T464 |
arg2Of |
hemoglobinopathies,of |
R258 |
T465 |
T467 |
arg1Of |
hemoglobinopathies,as |
R259 |
T467 |
T466 |
arg1Of |
as,such |
R260 |
T470 |
T471 |
arg1Of |
anemia,and |
R261 |
T471 |
T467 |
arg2Of |
and,as |
R262 |
T471 |
T468 |
arg1Of |
and,sickle |
R263 |
T471 |
T469 |
arg1Of |
and,cell |
R264 |
T472 |
T471 |
arg2Of |
thalassemia,and |
R3099 |
T4528 |
T4527 |
arg1Of |
Expression,Persistent |
R3100 |
T4528 |
T4529 |
arg1Of |
Expression,of |
R3101 |
T4528 |
T4535 |
arg1Of |
Expression,"," |
R3102 |
T4528 |
T4536 |
arg1Of |
Expression,in |
R3103 |
T4532 |
T4529 |
arg2Of |
Globin,of |
R3104 |
T4532 |
T4530 |
arg1Of |
Globin,the |
R3105 |
T4532 |
T4531 |
arg1Of |
Globin,Embryonic |
R3106 |
T4532 |
T4533 |
arg1Of |
Globin,"," |
R3107 |
T4534 |
T4533 |
arg2Of |
ɛy,"," |
R3108 |
T4538 |
T4536 |
arg2Of |
Mice,in |
R3109 |
T4538 |
T4537 |
arg1Of |
Mice,Sox6-Deficient |
R3110 |
T4542 |
T4539 |
arg1Of |
gene,The |
R3111 |
T4542 |
T4540 |
arg1Of |
gene,ɛy |
R3112 |
T4542 |
T4541 |
arg1Of |
gene,globin |
R3113 |
T4542 |
T4543 |
arg1Of |
gene,was |
R3114 |
T4542 |
T4545 |
arg2Of |
gene,identified |
R3115 |
T4545 |
T4543 |
arg2Of |
identified,was |
R3116 |
T4545 |
T4544 |
arg1Of |
identified,initially |
R3117 |
T4545 |
T4546 |
arg1Of |
identified,as |
R3118 |
T4549 |
T4546 |
arg2Of |
transcript,as |
R3119 |
T4549 |
T4547 |
arg1Of |
transcript,an |
R3120 |
T4549 |
T4548 |
arg2Of |
transcript,upregulated |
R3121 |
T4549 |
T4550 |
arg1Of |
transcript,in |
R3122 |
T4553 |
T4550 |
arg2Of |
mouse,in |
R3123 |
T4553 |
T4551 |
arg1Of |
mouse,the |
R3124 |
T4553 |
T4552 |
arg1Of |
mouse,p 100H |
R3125 |
T4553 |
T4554 |
arg1Of |
mouse,using |
R3126 |
T4554 |
T4557 |
modOf |
using,to |
R3127 |
T4556 |
T4554 |
arg2Of |
hybridization,using |
R3128 |
T4556 |
T4555 |
arg1Of |
hybridization,subtractive |
R3129 |
T4558 |
T4557 |
arg1Of |
identify,to |
R3130 |
T4561 |
T4558 |
arg2Of |
targets,identify |
R3131 |
T4561 |
T4559 |
arg1Of |
targets,Sox6 |
R3132 |
T4561 |
T4560 |
arg1Of |
targets,downstream |
R3133 |
T4564 |
T4562 |
arg1Of |
observation,This |
R3134 |
T4564 |
T4563 |
arg1Of |
observation,initial |
R3135 |
T4564 |
T4565 |
arg1Of |
observation,was |
R3136 |
T4564 |
T4566 |
arg2Of |
observation,confirmed |
R3137 |
T4566 |
T4565 |
arg2Of |
confirmed,was |
R3138 |
T4566 |
T4567 |
arg1Of |
confirmed,in |
R3139 |
T4566 |
T4574 |
arg1Of |
confirmed,[ |
R3140 |
T4571 |
T4567 |
arg2Of |
allele,in |
R3141 |
T4571 |
T4568 |
arg1Of |
allele,an |
R3142 |
T4571 |
T4569 |
arg1Of |
allele,independent |
R3143 |
T4571 |
T4570 |
arg1Of |
allele,knock-out |
R3144 |
T4571 |
T4572 |
arg1Of |
allele,of |
R3145 |
T4573 |
T4572 |
arg2Of |
Sox6,of |
R3146 |
T4575 |
T4574 |
arg2Of |
13,[ |
R3147 |
T4576 |
T4574 |
arg3Of |
],[ |
R3148 |
T4577 |
T4566 |
arg3Of |
using,confirmed |
R3149 |
T4581 |
T4577 |
arg2Of |
reaction,using |
R3150 |
T4581 |
T4578 |
arg1Of |
reaction,real-time |
R3151 |
T4581 |
T4579 |
arg1Of |
reaction,polymerase |
R3152 |
T4581 |
T4580 |
arg1Of |
reaction,chain |
R3153 |
T4581 |
T4582 |
arg1Of |
reaction,( |
R3154 |
T4581 |
T4585 |
arg1Of |
reaction,( |
R3155 |
T4583 |
T4582 |
arg2Of |
PCR,( |
R3156 |
T4584 |
T4582 |
arg3Of |
),( |
R3157 |
T4587 |
T4585 |
arg2Of |
data,( |
R3158 |
T4587 |
T4586 |
arg1Of |
data,unpublished |
R3159 |
T4588 |
T4585 |
arg3Of |
),( |
R3160 |
T4590 |
T4589 |
arg1Of |
PCR,Real-time |
R3161 |
T4590 |
T4591 |
arg1Of |
PCR,was |
R3162 |
T4590 |
T4592 |
arg2Of |
PCR,used |
R3163 |
T4592 |
T4591 |
arg2Of |
used,was |
R3164 |
T4594 |
T4592 |
arg3Of |
quantitate,used |
R3165 |
T4594 |
T4593 |
arg1Of |
quantitate,to |
R3166 |
T4594 |
T4609 |
arg1Of |
quantitate,at |
R3167 |
T4597 |
T4594 |
arg2Of |
levels,quantitate |
R3168 |
T4597 |
T4595 |
arg1Of |
levels,the |
R3169 |
T4597 |
T4596 |
arg1Of |
levels,expression |
R3170 |
T4597 |
T4598 |
arg1Of |
levels,of |
R3171 |
T4601 |
T4598 |
arg2Of |
genes,of |
R3172 |
T4601 |
T4599 |
arg1Of |
genes,other |
R3173 |
T4601 |
T4600 |
arg1Of |
genes,globin |
R3174 |
T4601 |
T4602 |
arg1Of |
genes,in |
R3175 |
T4604 |
T4603 |
arg1Of |
mutant,p100H |
R3176 |
T4604 |
T4605 |
arg1Of |
mutant,and |
R3177 |
T4605 |
T4602 |
arg2Of |
and,in |
R3178 |
T4608 |
T4605 |
arg2Of |
livers,and |
R3179 |
T4608 |
T4606 |
arg1Of |
livers,WT |
R3180 |
T4608 |
T4607 |
arg1Of |
livers,mouse |
R3181 |
T4612 |
T4610 |
arg1Of |
stages,two |
R3182 |
T4612 |
T4611 |
arg1Of |
stages,developmental |
R3183 |
T4612 |
T4613 |
arg1Of |
stages,"," |
R3184 |
T4613 |
T4616 |
arg1Of |
",",and |
R3185 |
T4615 |
T4613 |
arg2Of |
dpc,"," |
R3186 |
T4615 |
T4614 |
arg1Of |
dpc,15.5 |
R3187 |
T4616 |
T4609 |
arg2Of |
and,at |
R3188 |
T4618 |
T4616 |
arg2Of |
dpc,and |
R3189 |
T4618 |
T4617 |
arg1Of |
dpc,18.5 |
R3190 |
T4620 |
T4619 |
arg2Of |
shown,As |
R3191 |
T4620 |
T4621 |
arg1Of |
shown,in |
R3192 |
T4622 |
T4621 |
arg2Of |
Figure,in |
R3193 |
T4622 |
T4623 |
arg1Of |
Figure,1 |
R3194 |
T4627 |
T4625 |
arg1Of |
gene,the |
R3195 |
T4627 |
T4626 |
arg1Of |
gene,ɛy |
R3196 |
T4627 |
T4628 |
arg1Of |
gene,is |
R3197 |
T4627 |
T4629 |
arg2Of |
gene,expressed |
R3198 |
T4629 |
T4619 |
arg1Of |
expressed,As |
R3199 |
T4629 |
T4624 |
arg1Of |
expressed,"," |
R3200 |
T4629 |
T4628 |
arg2Of |
expressed,is |
R3201 |
T4629 |
T4630 |
arg1Of |
expressed,at |
R3202 |
T4629 |
T4633 |
arg1Of |
expressed,at |
R3203 |
T4629 |
T4637 |
arg1Of |
expressed,in |
R3204 |
T4629 |
T4640 |
arg1Of |
expressed,"," |
R3205 |
T4629 |
T4641 |
arg1Of |
expressed,in |
R3206 |
T4632 |
T4630 |
arg2Of |
levels,at |
R3207 |
T4632 |
T4631 |
arg1Of |
levels,high |
R3208 |
T4636 |
T4633 |
arg2Of |
points,at |
R3209 |
T4636 |
T4634 |
arg1Of |
points,both |
R3210 |
T4636 |
T4635 |
arg1Of |
points,time |
R3211 |
T4639 |
T4637 |
arg2Of |
mice,in |
R3212 |
T4639 |
T4638 |
arg1Of |
mice,mutant |
R3213 |
T4641 |
T4643 |
arg1Of |
in,to |
R3214 |
T4642 |
T4641 |
arg2Of |
contrast,in |
R3215 |
T4645 |
T4641 |
arg3Of |
decline,in |
R3216 |
T4645 |
T4644 |
arg1Of |
decline,the |
R3217 |
T4645 |
T4646 |
arg1Of |
decline,in |
R3218 |
T4647 |
T4646 |
arg2Of |
expression,in |
R3219 |
T4647 |
T4648 |
arg2Of |
expression,observed |
R3220 |
T4648 |
T4649 |
arg1Of |
observed,in |
R3221 |
T4651 |
T4649 |
arg2Of |
mice,in |
R3222 |
T4651 |
T4650 |
arg1Of |
mice,WT |
R3223 |
T4653 |
T4652 |
arg1Of |
difference,No |
R3224 |
T4653 |
T4654 |
arg1Of |
difference,was |
R3225 |
T4653 |
T4655 |
arg2Of |
difference,seen |
R3226 |
T4655 |
T4654 |
arg2Of |
seen,was |
R3227 |
T4655 |
T4656 |
arg1Of |
seen,between |
R3228 |
T4657 |
T4658 |
arg1Of |
WT,and |
R3229 |
T4659 |
T4658 |
arg2Of |
heterozygous,and |
R3230 |
T4660 |
T4656 |
arg2Of |
mice,between |
R3231 |
T4660 |
T4657 |
arg1Of |
mice,WT |
R3232 |
T4660 |
T4659 |
arg1Of |
mice,heterozygous |
R3233 |
T4660 |
T4661 |
arg1Of |
mice,( |
R3234 |
T4663 |
T4661 |
arg2Of |
data,( |
R3235 |
T4663 |
T4662 |
arg1Of |
data,unpublished |
R3236 |
T4664 |
T4661 |
arg3Of |
),( |
R3237 |
T4669 |
T4667 |
arg1Of |
levels,the |
R3238 |
T4669 |
T4668 |
arg1Of |
levels,expression |
R3239 |
T4669 |
T4670 |
arg1Of |
levels,of |
R3240 |
T4669 |
T4682 |
arg1Of |
levels,are |
R3241 |
T4669 |
T4684 |
arg1Of |
levels,higher |
R3242 |
T4676 |
T4670 |
arg2Of |
genes,of |
R3243 |
T4676 |
T4671 |
arg1Of |
genes,the |
R3244 |
T4676 |
T4672 |
arg1Of |
genes,other |
R3245 |
T4676 |
T4673 |
arg1Of |
genes,two |
R3246 |
T4676 |
T4674 |
arg1Of |
genes,embryonic |
R3247 |
T4676 |
T4675 |
arg1Of |
genes,globin |
R3248 |
T4676 |
T4677 |
arg1Of |
genes,( |
R3249 |
T4678 |
T4679 |
arg1Of |
ζ,and |
R3250 |
T4679 |
T4677 |
arg2Of |
and,( |
R3251 |
T4680 |
T4679 |
arg2Of |
βh1,and |
R3252 |
T4681 |
T4677 |
arg3Of |
),( |
R3253 |
T4682 |
T4665 |
arg1Of |
are,Interestingly |
R3254 |
T4682 |
T4666 |
arg1Of |
are,"," |
R3255 |
T4682 |
T4683 |
arg1Of |
are,also |
R3256 |
T4682 |
T4689 |
arg1Of |
are,"," |
R3257 |
T4682 |
T4690 |
arg1Of |
are,compared |
R3258 |
T4684 |
T4682 |
arg2Of |
higher,are |
R3259 |
T4684 |
T4685 |
arg1Of |
higher,in |
R3260 |
T4688 |
T4685 |
arg2Of |
mice,in |
R3261 |
T4688 |
T4686 |
arg1Of |
mice,p100H |
R3262 |
T4688 |
T4687 |
arg1Of |
mice,homozygous |
R3263 |
T4691 |
T4695 |
arg1Of |
with,but |
R3264 |
T4693 |
T4691 |
arg2Of |
mice,with |
R3265 |
T4693 |
T4692 |
arg1Of |
mice,WT |
R3266 |
T4695 |
T4690 |
arg2Of |
but,compared |
R3267 |
T4695 |
T4694 |
arg1Of |
but,"," |
R3268 |
T4696 |
T4695 |
arg2Of |
to,but |
R3269 |
T4699 |
T4698 |
arg1Of |
lesser,much |
R3270 |
T4700 |
T4696 |
arg2Of |
extent,to |
R3271 |
T4700 |
T4697 |
arg1Of |
extent,a |
R3272 |
T4700 |
T4699 |
arg1Of |
extent,lesser |
R3273 |
T4700 |
T4701 |
arg1Of |
extent,than |
R3274 |
T4702 |
T4701 |
arg2Of |
seen,than |
R3275 |
T4702 |
T4703 |
arg1Of |
seen,for |
R3276 |
T4702 |
T4706 |
arg1Of |
seen,at |
R3277 |
T4705 |
T4703 |
arg2Of |
globin,for |
R3278 |
T4705 |
T4704 |
arg1Of |
globin,ɛy |
R3279 |
T4708 |
T4706 |
arg2Of |
dpc,at |
R3280 |
T4708 |
T4707 |
arg1Of |
dpc,18.5 |
R3281 |
T4708 |
T4709 |
arg1Of |
dpc,( |
R3282 |
T4710 |
T4709 |
arg2Of |
Figure,( |
R3283 |
T4710 |
T4711 |
arg1Of |
Figure,1 |
R3284 |
T4712 |
T4709 |
arg3Of |
),( |
R3285 |
T4717 |
T4715 |
arg1Of |
level,the |
R3286 |
T4717 |
T4716 |
arg1Of |
level,expression |
R3287 |
T4717 |
T4718 |
arg1Of |
level,of |
R3288 |
T4717 |
T4722 |
arg1Of |
level,is |
R3289 |
T4717 |
T4725 |
arg1Of |
level,higher |
R3290 |
T4721 |
T4718 |
arg2Of |
globin,of |
R3291 |
T4721 |
T4719 |
arg1Of |
globin,adult |
R3292 |
T4721 |
T4720 |
arg1Of |
globin,β |
R3293 |
T4722 |
T4713 |
arg1Of |
is,Moreover |
R3294 |
T4722 |
T4714 |
arg1Of |
is,"," |
R3295 |
T4722 |
T4723 |
arg1Of |
is,also |
R3296 |
T4722 |
T4734 |
arg1Of |
is,at |
R3297 |
T4725 |
T4722 |
arg2Of |
higher,is |
R3298 |
T4725 |
T4724 |
arg1Of |
higher,somewhat |
R3299 |
T4725 |
T4726 |
arg1Of |
higher,in |
R3300 |
T4725 |
T4730 |
arg1Of |
higher,than |
R3301 |
T4729 |
T4726 |
arg2Of |
mice,in |
R3302 |
T4729 |
T4727 |
arg1Of |
mice,p100H |
R3303 |
T4729 |
T4728 |
arg1Of |
mice,homozygous |
R3304 |
T4731 |
T4730 |
arg2Of |
in,than |
R3305 |
T4733 |
T4731 |
arg2Of |
mice,in |
R3306 |
T4733 |
T4732 |
arg1Of |
mice,WT |
R3307 |
T4736 |
T4734 |
arg2Of |
dpc,at |
R3308 |
T4736 |
T4735 |
arg1Of |
dpc,18.5 |
R3309 |
T4736 |
T4737 |
arg1Of |
dpc,( |
R3310 |
T4738 |
T4737 |
arg2Of |
Figure,( |
R3311 |
T4738 |
T4739 |
arg1Of |
Figure,1 |
R3312 |
T4740 |
T4737 |
arg3Of |
),( |
R3313 |
T4742 |
T4741 |
arg1Of |
lethality,Perinatal |
R3314 |
T4742 |
T4743 |
arg1Of |
lethality,of |
R3315 |
T4742 |
T4746 |
arg1Of |
lethality,( |
R3316 |
T4742 |
T4756 |
arg1Of |
lethality,precludes |
R3317 |
T4745 |
T4743 |
arg2Of |
mice,of |
R3318 |
T4745 |
T4744 |
arg1Of |
mice,mutant |
R3319 |
T4748 |
T4746 |
arg2Of |
from,( |
R3320 |
T4748 |
T4747 |
arg1Of |
from,presumably |
R3321 |
T4751 |
T4748 |
arg2Of |
defect,from |
R3322 |
T4751 |
T4749 |
arg1Of |
defect,the |
R3323 |
T4751 |
T4750 |
arg1Of |
defect,heart |
R3324 |
T4751 |
T4752 |
arg1Of |
defect,[ |
R3325 |
T4753 |
T4752 |
arg2Of |
14,[ |
R3326 |
T4754 |
T4752 |
arg3Of |
],[ |
R3327 |
T4755 |
T4746 |
arg3Of |
),( |
R3328 |
T4756 |
T4758 |
arg1Of |
precludes,from |
R3329 |
T4757 |
T4756 |
arg2Of |
us,precludes |
R3330 |
T4759 |
T4758 |
arg2Of |
evaluating,from |
R3331 |
T4762 |
T4759 |
arg2Of |
expression,evaluating |
R3332 |
T4762 |
T4760 |
arg1Of |
expression,postnatal |
R3333 |
T4762 |
T4761 |
arg1Of |
expression,globin |
R3334 |
T4764 |
T4763 |
arg1Of |
graphs,The |
R3335 |
T4764 |
T4765 |
arg1Of |
graphs,in |
R3336 |
T4764 |
T4773 |
arg1Of |
graphs,that |
R3337 |
T4764 |
T4774 |
arg1Of |
graphs,were |
R3338 |
T4764 |
T4775 |
arg2Of |
graphs,performed |
R3339 |
T4772 |
T4765 |
arg2Of |
results,in |
R3340 |
T4772 |
T4766 |
arg1Of |
results,Figure |
R3341 |
T4772 |
T4767 |
arg1Of |
results,1 |
R3342 |
T4772 |
T4768 |
arg1Of |
results,illustrate |
R3343 |
T4772 |
T4769 |
arg1Of |
results,real |
R3344 |
T4772 |
T4770 |
arg1Of |
results,time |
R3345 |
T4772 |
T4771 |
arg1Of |
results,PCR |
R3346 |
T4775 |
T4774 |
arg2Of |
performed,were |
R3347 |
T4775 |
T4776 |
arg1Of |
performed,in |
R3348 |
T4777 |
T4776 |
arg2Of |
triplicate,in |
R3349 |
T4777 |
T4778 |
arg1Of |
triplicate,( |
R3350 |
T4780 |
T4779 |
arg1Of |
deviation,standard |
R3351 |
T4780 |
T4781 |
arg1Of |
deviation,of |
R3352 |
T4780 |
T4784 |
arg1Of |
deviation,is |
R3353 |
T4780 |
T4785 |
arg2Of |
deviation,shown |
R3354 |
T4783 |
T4781 |
arg2Of |
data,of |
R3355 |
T4783 |
T4782 |
arg1Of |
data,the |
R3356 |
T4785 |
T4778 |
arg2Of |
shown,( |
R3357 |
T4785 |
T4784 |
arg2Of |
shown,is |
R3358 |
T4788 |
T4785 |
arg1Of |
bars,shown |
R3359 |
T4788 |
T4786 |
arg2Of |
bars,by |
R3360 |
T4788 |
T4787 |
arg1Of |
bars,error |
R3361 |
T4789 |
T4778 |
arg3Of |
),( |
R3362 |
T4791 |
T4792 |
arg1Of |
all,of |
R3363 |
T4791 |
T4795 |
arg1Of |
all,were |
R3364 |
T4791 |
T4796 |
arg2Of |
all,performed |
R3365 |
T4794 |
T4792 |
arg2Of |
assays,of |
R3366 |
T4794 |
T4793 |
arg1Of |
assays,the |
R3367 |
T4796 |
T4790 |
arg2Of |
performed,Because |
R3368 |
T4796 |
T4795 |
arg2Of |
performed,were |
R3369 |
T4796 |
T4797 |
arg1Of |
performed,at |
R3370 |
T4800 |
T4797 |
arg2Of |
time,at |
R3371 |
T4800 |
T4798 |
arg1Of |
time,the |
R3372 |
T4800 |
T4799 |
arg1Of |
time,same |
R3373 |
T4800 |
T4801 |
arg1Of |
time,with |
R3374 |
T4805 |
T4801 |
arg2Of |
control,with |
R3375 |
T4805 |
T4802 |
arg1Of |
control,the |
R3376 |
T4805 |
T4803 |
arg1Of |
control,same |
R3377 |
T4805 |
T4804 |
arg1Of |
control,internal |
R3378 |
T4808 |
T4807 |
arg1Of |
levels,the |
R3379 |
T4808 |
T4809 |
arg2Of |
levels,shown |
R3380 |
T4808 |
T4810 |
arg1Of |
levels,are |
R3381 |
T4808 |
T4814 |
arg1Of |
levels,are |
R3382 |
T4808 |
T4816 |
arg1Of |
levels,comparable |
R3383 |
T4808 |
T4821 |
arg1Of |
levels,are |
R3384 |
T4808 |
T4822 |
arg1Of |
levels,in |
R3385 |
T4810 |
T4813 |
arg1Of |
are,and |
R3386 |
T4812 |
T4810 |
arg2Of |
levels,are |
R3387 |
T4812 |
T4811 |
arg1Of |
levels,relative |
R3388 |
T4813 |
T4790 |
arg1Of |
and,Because |
R3389 |
T4813 |
T4806 |
arg1Of |
and,"," |
R3390 |
T4814 |
T4815 |
arg1Of |
are,thus |
R3391 |
T4814 |
T4817 |
arg1Of |
are,across |
R3392 |
T4814 |
T4820 |
arg1Of |
are,and |
R3393 |
T4816 |
T4814 |
arg2Of |
comparable,are |
R3394 |
T4819 |
T4817 |
arg2Of |
samples,across |
R3395 |
T4819 |
T4818 |
arg1Of |
samples,all |
R3396 |
T4820 |
T4813 |
arg2Of |
and,and |
R3397 |
T4821 |
T4820 |
arg2Of |
are,and |
R3398 |
T4822 |
T4821 |
arg2Of |
in,are |
R3399 |
T4823 |
T4822 |
arg2Of |
agreement,in |
R3400 |
T4823 |
T4824 |
arg1Of |
agreement,with |
R3401 |
T4826 |
T4825 |
arg1Of |
published,previously |
R3402 |
T4827 |
T4824 |
arg2Of |
results,with |
R3403 |
T4827 |
T4826 |
arg1Of |
results,published |
R3404 |
T4827 |
T4828 |
arg1Of |
results,for |
R3405 |
T4831 |
T4828 |
arg2Of |
mice,for |
R3406 |
T4831 |
T4829 |
arg1Of |
mice,WT |
R3407 |
T4831 |
T4830 |
arg1Of |
mice,fetal |
R3408 |
T4831 |
T4832 |
arg1Of |
mice,[ |
R3409 |
T4833 |
T4832 |
arg2Of |
29,[ |
R3410 |
T4834 |
T4832 |
arg3Of |
],[ |
R3411 |
T4835 |
T4836 |
arg1Of |
We,note |
R3412 |
T4839 |
T4838 |
arg1Of |
level,the |
R3413 |
T4839 |
T4840 |
arg1Of |
level,of |
R3414 |
T4839 |
T4855 |
arg1Of |
level,is |
R3415 |
T4839 |
T4857 |
arg1Of |
level,equivalent |
R3416 |
T4842 |
T4840 |
arg2Of |
expression,of |
R3417 |
T4842 |
T4841 |
arg1Of |
expression,ɛy |
R3418 |
T4842 |
T4843 |
arg1Of |
expression,in |
R3419 |
T4845 |
T4843 |
arg2Of |
livers,in |
R3420 |
T4845 |
T4844 |
arg1Of |
livers,the |
R3421 |
T4845 |
T4846 |
arg1Of |
livers,of |
R3422 |
T4848 |
T4847 |
arg1Of |
dpc,15.5 |
R3423 |
T4848 |
T4849 |
arg1Of |
dpc,and |
R3424 |
T4849 |
T4846 |
arg2Of |
and,of |
R3425 |
T4854 |
T4849 |
arg2Of |
mice,and |
R3426 |
T4854 |
T4850 |
arg1Of |
mice,18.5 |
R3427 |
T4854 |
T4851 |
arg1Of |
mice,dpc |
R3428 |
T4854 |
T4852 |
arg1Of |
mice,homozygous |
R3429 |
T4854 |
T4853 |
arg1Of |
mice,mutant |
R3430 |
T4855 |
T4836 |
arg2Of |
is,note |
R3431 |
T4855 |
T4837 |
arg1Of |
is,that |
R3432 |
T4857 |
T4855 |
arg2Of |
equivalent,is |
R3433 |
T4857 |
T4856 |
arg1Of |
equivalent,statistically |
R3434 |
T4857 |
T4858 |
arg1Of |
equivalent,to |
R3435 |
T4860 |
T4858 |
arg2Of |
level,to |
R3436 |
T4860 |
T4859 |
arg1Of |
level,the |
R3437 |
T4860 |
T4861 |
arg1Of |
level,of |
R3438 |
T4863 |
T4861 |
arg2Of |
expression,of |
R3439 |
T4863 |
T4862 |
arg1Of |
expression,βmaj/min |
R3440 |
T4863 |
T4864 |
arg1Of |
expression,in |
R3441 |
T4866 |
T4864 |
arg2Of |
livers,in |
R3442 |
T4866 |
T4865 |
arg1Of |
livers,the |
R3443 |
T4866 |
T4867 |
arg1Of |
livers,of |
R3444 |
T4869 |
T4868 |
arg1Of |
dpc,15.5 |
R3445 |
T4869 |
T4870 |
arg1Of |
dpc,and |
R3446 |
T4870 |
T4867 |
arg2Of |
and,of |
R3447 |
T4875 |
T4870 |
arg2Of |
mice,and |
R3448 |
T4875 |
T4871 |
arg1Of |
mice,18.5 |
R3449 |
T4875 |
T4872 |
arg1Of |
mice,dpc |
R3450 |
T4875 |
T4873 |
arg1Of |
mice,homozygous |
R3451 |
T4875 |
T4874 |
arg1Of |
mice,WT |
R3966 |
T5817 |
T5816 |
arg1Of |
Studies,Transfection |
R3967 |
T5817 |
T5818 |
arg1Of |
Studies,Using |
R3968 |
T5817 |
T5825 |
arg1Of |
Studies,Represses |
R3969 |
T5821 |
T5819 |
arg1Of |
Indicate,GM979 |
R3970 |
T5821 |
T5820 |
arg1Of |
Indicate,Cells |
R3971 |
T5823 |
T5818 |
arg2Of |
Sox6,Using |
R3972 |
T5823 |
T5821 |
arg1Of |
Sox6,Indicate |
R3973 |
T5823 |
T5822 |
arg1Of |
Sox6,That |
R3974 |
T5825 |
T5824 |
arg1Of |
Represses,Directly |
R3975 |
T5829 |
T5825 |
arg2Of |
Promoter,Represses |
R3976 |
T5829 |
T5826 |
arg1Of |
Promoter,the |
R3977 |
T5829 |
T5827 |
arg1Of |
Promoter,ɛy |
R3978 |
T5829 |
T5828 |
arg1Of |
Promoter,Gene |
R3979 |
T5829 |
T5830 |
arg1Of |
Promoter,at |
R3980 |
T5833 |
T5830 |
arg2Of |
Level,at |
R3981 |
T5833 |
T5831 |
arg1Of |
Level,the |
R3982 |
T5833 |
T5832 |
arg1Of |
Level,Transcriptional |
R3983 |
T5838 |
T5837 |
arg2Of |
Figure,( |
R3984 |
T5838 |
T5839 |
arg1Of |
Figure,1 |
R3985 |
T5840 |
T5837 |
arg3Of |
),( |
R3986 |
T5843 |
T5834 |
arg1Of |
levels,Real-time |
R3987 |
T5843 |
T5835 |
arg1Of |
levels,PCR |
R3988 |
T5843 |
T5836 |
arg1Of |
levels,assays |
R3989 |
T5843 |
T5837 |
arg1Of |
levels,( |
R3990 |
T5843 |
T5841 |
arg1Of |
levels,measure |
R3991 |
T5843 |
T5842 |
arg1Of |
levels,steady-state |
R3992 |
T5843 |
T5844 |
arg1Of |
levels,of |
R3993 |
T5846 |
T5844 |
arg2Of |
mRNA,of |
R3994 |
T5846 |
T5845 |
arg1Of |
mRNA,ɛy |
R3995 |
T5846 |
T5847 |
arg1Of |
mRNA,"," |
R3996 |
T5850 |
T5847 |
arg2Of |
activity,"," |
R3997 |
T5850 |
T5848 |
arg1Of |
activity,not |
R3998 |
T5850 |
T5849 |
arg1Of |
activity,transcriptional |
R3999 |
T5850 |
T5851 |
arg1Of |
activity,of |
R4000 |
T5854 |
T5851 |
arg2Of |
promoter,of |
R4001 |
T5854 |
T5852 |
arg1Of |
promoter,the |
R4002 |
T5854 |
T5853 |
arg1Of |
promoter,ɛy |
R4003 |
T5856 |
T5855 |
arg1Of |
investigate,To |
R4004 |
T5858 |
T5860 |
arg1Of |
Sox6,acts |
R4005 |
T5860 |
T5856 |
arg2Of |
acts,investigate |
R4006 |
T5860 |
T5857 |
arg1Of |
acts,whether |
R4007 |
T5860 |
T5859 |
arg1Of |
acts,directly |
R4008 |
T5860 |
T5861 |
arg1Of |
acts,on |
R4009 |
T5860 |
T5866 |
arg1Of |
acts,at |
R4010 |
T5865 |
T5861 |
arg2Of |
promoter,on |
R4011 |
T5865 |
T5862 |
arg1Of |
promoter,the |
R4012 |
T5865 |
T5863 |
arg1Of |
promoter,ɛy |
R4013 |
T5865 |
T5864 |
arg1Of |
promoter,gene |
R4014 |
T5869 |
T5866 |
arg2Of |
level,at |
R4015 |
T5869 |
T5867 |
arg1Of |
level,the |
R4016 |
T5869 |
T5868 |
arg1Of |
level,transcriptional |
R4017 |
T5871 |
T5856 |
arg1Of |
we,investigate |
R4018 |
T5871 |
T5872 |
arg1Of |
we,used |
R4019 |
T5872 |
T5855 |
modOf |
used,To |
R4020 |
T5872 |
T5870 |
arg1Of |
used,"," |
R4021 |
T5875 |
T5874 |
arg1Of |
vitro,in |
R4022 |
T5876 |
T5875 |
arg1Of |
transient,vitro |
R4023 |
T5878 |
T5873 |
arg1Of |
assay,an |
R4024 |
T5878 |
T5876 |
arg1Of |
assay,transient |
R4025 |
T5878 |
T5877 |
arg1Of |
assay,transfection |
R4026 |
T5878 |
T5879 |
arg1Of |
assay,and |
R4027 |
T5879 |
T5872 |
arg2Of |
and,used |
R4028 |
T5881 |
T5879 |
arg2Of |
cells,and |
R4029 |
T5881 |
T5880 |
arg1Of |
cells,GM979 |
R4030 |
T5881 |
T5882 |
arg1Of |
cells,"," |
R4031 |
T5887 |
T5882 |
arg2Of |
line,"," |
R4032 |
T5887 |
T5883 |
arg1Of |
line,a |
R4033 |
T5887 |
T5884 |
arg1Of |
line,murine |
R4034 |
T5887 |
T5885 |
arg1Of |
line,erythroleukemic |
R4035 |
T5887 |
T5886 |
arg1Of |
line,cell |
R4036 |
T5887 |
T5888 |
arg1Of |
line,that |
R4037 |
T5887 |
T5889 |
arg1Of |
line,expresses |
R4038 |
T5891 |
T5892 |
arg1Of |
ɛy,and |
R4039 |
T5893 |
T5892 |
arg2Of |
adult,and |
R4040 |
T5895 |
T5889 |
arg2Of |
globins,expresses |
R4041 |
T5895 |
T5890 |
arg1Of |
globins,both |
R4042 |
T5895 |
T5891 |
arg1Of |
globins,ɛy |
R4043 |
T5895 |
T5893 |
arg1Of |
globins,adult |
R4044 |
T5895 |
T5894 |
arg1Of |
globins,beta |
R4045 |
T5895 |
T5896 |
arg1Of |
globins,[ |
R4046 |
T5897 |
T5896 |
arg2Of |
30,[ |
R4047 |
T5898 |
T5896 |
arg3Of |
],[ |
R4048 |
T5899 |
T5900 |
arg1Of |
We,generated |
R4049 |
T5899 |
T5910 |
arg1Of |
We,fusing |
R4050 |
T5900 |
T5909 |
arg1Of |
generated,by |
R4051 |
T5900 |
T5940 |
arg1Of |
generated,"," |
R4052 |
T5900 |
T5941 |
arg1Of |
generated,as |
R4053 |
T5905 |
T5900 |
arg2Of |
construct,generated |
R4054 |
T5905 |
T5901 |
arg1Of |
construct,an |
R4055 |
T5905 |
T5902 |
arg1Of |
construct,ɛy |
R4056 |
T5905 |
T5903 |
arg1Of |
construct,promoter |
R4057 |
T5905 |
T5904 |
arg1Of |
construct,reporter |
R4058 |
T5905 |
T5906 |
arg1Of |
construct,( |
R4059 |
T5907 |
T5906 |
arg2Of |
E-Luc,( |
R4060 |
T5908 |
T5906 |
arg3Of |
),( |
R4061 |
T5910 |
T5909 |
arg2Of |
fusing,by |
R4062 |
T5910 |
T5933 |
arg1Of |
fusing,"," |
R4063 |
T5910 |
T5934 |
modOf |
fusing,followed |
R4064 |
T5914 |
T5913 |
arg2Of |
μLCR,( |
R4065 |
T5915 |
T5913 |
arg3Of |
),( |
R4066 |
T5916 |
T5910 |
arg2Of |
element,fusing |
R4067 |
T5916 |
T5911 |
arg1Of |
element,a |
R4068 |
T5916 |
T5912 |
arg1Of |
element,micro-LCR |
R4069 |
T5916 |
T5913 |
arg1Of |
element,( |
R4070 |
T5916 |
T5917 |
arg1Of |
element,( |
R4071 |
T5916 |
T5921 |
arg1Of |
element,[ |
R4072 |
T5916 |
T5924 |
arg1Of |
element,to |
R4073 |
T5919 |
T5917 |
arg2Of |
kb,( |
R4074 |
T5919 |
T5918 |
arg1Of |
kb,2.5 |
R4075 |
T5920 |
T5917 |
arg3Of |
),( |
R4076 |
T5922 |
T5921 |
arg2Of |
31,[ |
R4077 |
T5923 |
T5921 |
arg3Of |
],[ |
R4078 |
T5928 |
T5924 |
arg2Of |
promoter,to |
R4079 |
T5928 |
T5925 |
arg1Of |
promoter,the |
R4080 |
T5928 |
T5926 |
arg1Of |
promoter,ɛy |
R4081 |
T5928 |
T5927 |
arg1Of |
promoter,proximal |
R4082 |
T5928 |
T5929 |
arg1Of |
promoter,( |
R4083 |
T5931 |
T5929 |
arg2Of |
kb,( |
R4084 |
T5931 |
T5930 |
arg1Of |
kb,2.2 |
R4085 |
T5932 |
T5929 |
arg3Of |
),( |
R4086 |
T5939 |
T5934 |
arg1Of |
gene,followed |
R4087 |
T5939 |
T5935 |
arg2Of |
gene,by |
R4088 |
T5939 |
T5936 |
arg1Of |
gene,the |
R4089 |
T5939 |
T5937 |
arg1Of |
gene,luciferase |
R4090 |
T5939 |
T5938 |
arg1Of |
gene,reporter |
R4091 |
T5942 |
T5941 |
arg2Of |
shown,as |
R4092 |
T5942 |
T5943 |
arg1Of |
shown,in |
R4093 |
T5945 |
T5943 |
arg2Of |
2A,in |
R4094 |
T5945 |
T5944 |
arg1Of |
2A,Figure |
R4095 |
T5945 |
T5946 |
arg1Of |
2A,( |
R4096 |
T5947 |
T5946 |
arg2Of |
detailed,( |
R4097 |
T5947 |
T5948 |
arg1Of |
detailed,in |
R4098 |
T5949 |
T5950 |
arg1Of |
Materials,and |
R4099 |
T5950 |
T5948 |
arg2Of |
and,in |
R4100 |
T5951 |
T5950 |
arg2Of |
Methods,and |
R4101 |
T5952 |
T5946 |
arg3Of |
),( |
R4102 |
T5953 |
T5954 |
arg1Of |
Overexpression,of |
R4103 |
T5953 |
T5956 |
arg1Of |
Overexpression,in |
R4104 |
T5953 |
T5959 |
arg1Of |
Overexpression,by |
R4105 |
T5953 |
T5962 |
arg1Of |
Overexpression,leads |
R4106 |
T5955 |
T5954 |
arg2Of |
Sox6,of |
R4107 |
T5958 |
T5956 |
arg2Of |
cells,in |
R4108 |
T5958 |
T5957 |
arg1Of |
cells,GM979 |
R4109 |
T5961 |
T5959 |
arg2Of |
transfection,by |
R4110 |
T5961 |
T5960 |
arg1Of |
transfection,transient |
R4111 |
T5962 |
T5963 |
arg1Of |
leads,to |
R4112 |
T5966 |
T5963 |
arg2Of |
repression,to |
R4113 |
T5966 |
T5964 |
arg1Of |
repression,a |
R4114 |
T5966 |
T5965 |
arg1Of |
repression,dosage-dependent |
R4115 |
T5966 |
T5967 |
arg1Of |
repression,of |
R4116 |
T5970 |
T5967 |
arg2Of |
activity,of |
R4117 |
T5970 |
T5968 |
arg1Of |
activity,E-Luc |
R4118 |
T5970 |
T5969 |
arg1Of |
activity,reporter |
R4119 |
T5970 |
T5971 |
arg1Of |
activity,( |
R4120 |
T5973 |
T5971 |
arg2Of |
2B,( |
R4121 |
T5973 |
T5972 |
arg1Of |
2B,Figure |
R4122 |
T5974 |
T5971 |
arg3Of |
),( |
R4123 |
T5976 |
T5975 |
arg2Of |
contrast,In |
R4124 |
T5978 |
T5979 |
arg1Of |
overexpression,of |
R4125 |
T5978 |
T6000 |
arg1Of |
overexpression,fails |
R4126 |
T5978 |
T6002 |
arg1Of |
overexpression,repress |
R4127 |
T5983 |
T5979 |
arg2Of |
protein,of |
R4128 |
T5983 |
T5980 |
arg1Of |
protein,a |
R4129 |
T5983 |
T5981 |
arg2Of |
protein,truncated |
R4130 |
T5983 |
T5982 |
arg1Of |
protein,Sox6 |
R4131 |
T5983 |
T5984 |
arg1Of |
protein,that |
R4132 |
T5983 |
T5985 |
arg1Of |
protein,lacks |
R4133 |
T5983 |
T5992 |
arg1Of |
protein,( |
R4134 |
T5985 |
T5989 |
arg1Of |
lacks,[ |
R4135 |
T5988 |
T5985 |
arg2Of |
domain,lacks |
R4136 |
T5988 |
T5986 |
arg1Of |
domain,its |
R4137 |
T5988 |
T5987 |
arg1Of |
domain,HMG |
R4138 |
T5990 |
T5989 |
arg2Of |
32,[ |
R4139 |
T5991 |
T5989 |
arg3Of |
],[ |
R4140 |
T5993 |
T5992 |
arg2Of |
similar,( |
R4141 |
T5993 |
T5994 |
arg1Of |
similar,to |
R4142 |
T5998 |
T5994 |
arg2Of |
allele,to |
R4143 |
T5998 |
T5995 |
arg1Of |
allele,the |
R4144 |
T5998 |
T5996 |
arg1Of |
allele,p 100H |
R4145 |
T5998 |
T5997 |
arg1Of |
allele,mouse |
R4146 |
T5999 |
T5992 |
arg3Of |
),( |
R4147 |
T6000 |
T5975 |
arg1Of |
fails,In |
R4148 |
T6000 |
T5977 |
arg1Of |
fails,"," |
R4149 |
T6002 |
T6000 |
arg2Of |
repress,fails |
R4150 |
T6002 |
T6001 |
arg1Of |
repress,to |
R4151 |
T6004 |
T6002 |
arg2Of |
activity,repress |
R4152 |
T6004 |
T6003 |
arg1Of |
activity,E-Luc |
R4153 |
T6004 |
T6005 |
arg1Of |
activity,( |
R4154 |
T6007 |
T6005 |
arg2Of |
2B,( |
R4155 |
T6007 |
T6006 |
arg1Of |
2B,Figure |
R4156 |
T6008 |
T6005 |
arg3Of |
),( |
R4157 |
T6010 |
T6009 |
arg1Of |
data,These |
R4158 |
T6010 |
T6011 |
arg1Of |
data,indicate |
R4159 |
T6013 |
T6014 |
arg1Of |
Sox6,acts |
R4160 |
T6013 |
T6016 |
arg1Of |
Sox6,repress |
R4161 |
T6014 |
T6011 |
arg2Of |
acts,indicate |
R4162 |
T6014 |
T6012 |
arg1Of |
acts,that |
R4163 |
T6016 |
T6014 |
arg2Of |
repress,acts |
R4164 |
T6016 |
T6015 |
arg1Of |
repress,to |
R4165 |
T6016 |
T6020 |
arg1Of |
repress,at |
R4166 |
T6019 |
T6016 |
arg2Of |
promoter,repress |
R4167 |
T6019 |
T6017 |
arg1Of |
promoter,the |
R4168 |
T6019 |
T6018 |
arg1Of |
promoter,ɛy |
R4169 |
T6023 |
T6020 |
arg2Of |
level,at |
R4170 |
T6023 |
T6021 |
arg1Of |
level,the |
R4171 |
T6023 |
T6022 |
arg1Of |
level,transcriptional |
R4172 |
T6024 |
T6025 |
arg1Of |
Sox6,has |
R4173 |
T6024 |
T6026 |
arg1Of |
Sox6,been |
R4174 |
T6024 |
T6027 |
arg2Of |
Sox6,shown |
R4175 |
T6024 |
T6029 |
arg1Of |
Sox6,act |
R4176 |
T6024 |
T6035 |
arg1Of |
Sox6,interact |
R4177 |
T6027 |
T6025 |
arg2Of |
shown,has |
R4178 |
T6027 |
T6026 |
arg2Of |
shown,been |
R4179 |
T6027 |
T6048 |
arg1Of |
shown,[ |
R4180 |
T6029 |
T6028 |
arg1Of |
act,to |
R4181 |
T6029 |
T6030 |
arg1Of |
act,as |
R4182 |
T6029 |
T6033 |
arg1Of |
act,and |
R4183 |
T6032 |
T6030 |
arg2Of |
repressor,as |
R4184 |
T6032 |
T6031 |
arg1Of |
repressor,a |
R4185 |
T6033 |
T6027 |
arg3Of |
and,shown |
R4186 |
T6035 |
T6033 |
arg2Of |
interact,and |
R4187 |
T6035 |
T6034 |
arg1Of |
interact,to |
R4188 |
T6035 |
T6036 |
arg1Of |
interact,with |
R4189 |
T6039 |
T6038 |
arg1Of |
expressed,widely |
R4190 |
T6040 |
T6036 |
arg2Of |
co-repressor,with |
R4191 |
T6040 |
T6037 |
arg1Of |
co-repressor,a |
R4192 |
T6040 |
T6039 |
arg1Of |
co-repressor,expressed |
R4193 |
T6040 |
T6041 |
arg1Of |
co-repressor,"," |
R4194 |
T6040 |
T6043 |
arg1Of |
co-repressor,"," |
R4195 |
T6040 |
T6044 |
arg1Of |
co-repressor,on |
R4196 |
T6042 |
T6041 |
arg2Of |
CtBP2,"," |
R4197 |
T6047 |
T6044 |
arg2Of |
promoter,on |
R4198 |
T6047 |
T6045 |
arg1Of |
promoter,the |
R4199 |
T6047 |
T6046 |
arg1Of |
promoter,fgf-3 |
R42 |
T254 |
T250 |
arg1Of |
Globin,Sox6 |
R4200 |
T6049 |
T6048 |
arg2Of |
5,[ |
R4201 |
T6050 |
T6048 |
arg3Of |
],[ |
R4202 |
T6051 |
T6052 |
arg1Of |
CtBP2,is |
R4203 |
T6051 |
T6053 |
arg2Of |
CtBP2,expressed |
R4204 |
T6053 |
T6052 |
arg2Of |
expressed,is |
R4205 |
T6053 |
T6054 |
arg1Of |
expressed,in |
R4206 |
T6056 |
T6054 |
arg2Of |
cells,in |
R4207 |
T6056 |
T6055 |
arg1Of |
cells,GM979 |
R4208 |
T6056 |
T6057 |
arg1Of |
cells,( |
R4209 |
T6059 |
T6057 |
arg2Of |
data,( |
R4210 |
T6059 |
T6058 |
arg1Of |
data,unpublished |
R4211 |
T6060 |
T6057 |
arg3Of |
),( |
R4212 |
T6062 |
T6061 |
arg1Of |
investigate,To |
R4213 |
T6065 |
T6064 |
arg1Of |
interaction,the |
R4214 |
T6065 |
T6066 |
arg1Of |
interaction,with |
R4215 |
T6065 |
T6068 |
arg1Of |
interaction,is |
R4216 |
T6065 |
T6069 |
arg2Of |
interaction,required |
R4217 |
T6067 |
T6066 |
arg2Of |
CtBP2,with |
R4218 |
T6069 |
T6062 |
arg2Of |
required,investigate |
R4219 |
T6069 |
T6063 |
arg1Of |
required,whether |
R4220 |
T6069 |
T6068 |
arg2Of |
required,is |
R4221 |
T6069 |
T6070 |
arg1Of |
required,for |
R4222 |
T6072 |
T6070 |
arg2Of |
repression,for |
R4223 |
T6072 |
T6071 |
arg1Of |
repression,Sox6 |
R4224 |
T6072 |
T6073 |
arg1Of |
repression,of |
R4225 |
T6076 |
T6073 |
arg2Of |
promoter,of |
R4226 |
T6076 |
T6074 |
arg1Of |
promoter,the |
R4227 |
T6076 |
T6075 |
arg1Of |
promoter,ɛy |
R4228 |
T6078 |
T6062 |
arg1Of |
we,investigate |
R4229 |
T6078 |
T6079 |
arg1Of |
we,introduced |
R4230 |
T6079 |
T6061 |
modOf |
introduced,To |
R4231 |
T6079 |
T6077 |
arg1Of |
introduced,"," |
R4232 |
T6082 |
T6079 |
arg2Of |
mutation,introduced |
R4233 |
T6082 |
T6080 |
arg1Of |
mutation,a |
R4234 |
T6082 |
T6081 |
arg1Of |
mutation,point |
R4235 |
T6082 |
T6083 |
arg1Of |
mutation,( |
R4236 |
T6082 |
T6086 |
arg1Of |
mutation,in |
R4237 |
T6084 |
T6083 |
arg2Of |
L386H,( |
R4238 |
T6085 |
T6083 |
arg3Of |
),( |
R4239 |
T6089 |
T6086 |
arg2Of |
protein,in |
R4240 |
T6089 |
T6087 |
arg1Of |
protein,the |
R4241 |
T6089 |
T6088 |
arg1Of |
protein,Sox6 |
R4242 |
T6089 |
T6090 |
arg1Of |
protein,that |
R4243 |
T6089 |
T6091 |
arg1Of |
protein,has |
R4244 |
T6089 |
T6092 |
arg1Of |
protein,been |
R4245 |
T6089 |
T6094 |
arg2Of |
protein,reported |
R4246 |
T6089 |
T6096 |
arg1Of |
protein,be |
R4247 |
T6089 |
T6097 |
arg1Of |
protein,sufficient |
R4248 |
T6094 |
T6091 |
arg2Of |
reported,has |
R4249 |
T6094 |
T6092 |
arg2Of |
reported,been |
R4250 |
T6094 |
T6093 |
arg1Of |
reported,previously |
R4251 |
T6096 |
T6094 |
arg3Of |
be,reported |
R4252 |
T6096 |
T6095 |
arg1Of |
be,to |
R4253 |
T6097 |
T6096 |
arg2Of |
sufficient,be |
R4254 |
T6099 |
T6097 |
arg2Of |
abolish,sufficient |
R4255 |
T6099 |
T6098 |
arg1Of |
abolish,to |
R4256 |
T6101 |
T6099 |
arg2Of |
interaction,abolish |
R4257 |
T6101 |
T6100 |
arg1Of |
interaction,Sox6-CtBP2 |
R4258 |
T6101 |
T6102 |
arg1Of |
interaction,[ |
R4259 |
T6103 |
T6102 |
arg2Of |
5,[ |
R4260 |
T6104 |
T6102 |
arg3Of |
],[ |
R4261 |
T6108 |
T6105 |
arg1Of |
change,This |
R4262 |
T6108 |
T6106 |
arg1Of |
change,amino |
R4263 |
T6108 |
T6107 |
arg1Of |
change,acid |
R4264 |
T6108 |
T6109 |
arg1Of |
change,is |
R4265 |
T6108 |
T6111 |
arg1Of |
change,in |
R4266 |
T6109 |
T6110 |
arg1Of |
is,not |
R4267 |
T6111 |
T6109 |
arg2Of |
in,is |
R4268 |
T6116 |
T6111 |
arg2Of |
domain,in |
R4269 |
T6116 |
T6112 |
arg1Of |
domain,the |
R4270 |
T6116 |
T6113 |
arg1Of |
domain,HMG |
R4271 |
T6116 |
T6114 |
arg1Of |
domain,DNA |
R4272 |
T6116 |
T6115 |
arg1Of |
domain,binding |
R4273 |
T6121 |
T6119 |
arg1Of |
version,this |
R4274 |
T6121 |
T6120 |
arg1Of |
version,mutant |
R4275 |
T6121 |
T6122 |
arg1Of |
version,of |
R4276 |
T6121 |
T6124 |
arg1Of |
version,retains |
R4277 |
T6123 |
T6122 |
arg2Of |
Sox6,of |
R4278 |
T6124 |
T6117 |
arg1Of |
retains,However |
R4279 |
T6124 |
T6118 |
arg1Of |
retains,"," |
R4280 |
T6124 |
T6140 |
arg1Of |
retains,"," |
R4281 |
T6124 |
T6141 |
modOf |
retains,indicating |
R4282 |
T6126 |
T6124 |
arg2Of |
ability,retains |
R4283 |
T6126 |
T6125 |
arg1Of |
ability,the |
R4284 |
T6126 |
T6127 |
modOf |
ability,to |
R4285 |
T6128 |
T6127 |
arg1Of |
repress,to |
R4286 |
T6131 |
T6128 |
arg2Of |
promoter,repress |
R4287 |
T6131 |
T6129 |
arg1Of |
promoter,the |
R4288 |
T6131 |
T6130 |
arg1Of |
promoter,ɛy |
R4289 |
T6131 |
T6132 |
arg1Of |
promoter,in |
R4290 |
T6135 |
T6132 |
arg2Of |
assay,in |
R4291 |
T6135 |
T6133 |
arg1Of |
assay,the |
R4292 |
T6135 |
T6134 |
arg1Of |
assay,transfection |
R4293 |
T6135 |
T6136 |
arg1Of |
assay,( |
R4294 |
T6138 |
T6136 |
arg2Of |
2B,( |
R4295 |
T6138 |
T6137 |
arg1Of |
2B,Figure |
R4296 |
T6139 |
T6136 |
arg3Of |
),( |
R4297 |
T6143 |
T6144 |
arg1Of |
Sox6,represses |
R4298 |
T6144 |
T6141 |
arg2Of |
represses,indicating |
R4299 |
T6144 |
T6142 |
arg1Of |
represses,that |
R43 |
T254 |
T251 |
arg1Of |
Globin,Directly |
R4300 |
T6144 |
T6148 |
arg1Of |
represses,in |
R4301 |
T6147 |
T6144 |
arg2Of |
promoter,represses |
R4302 |
T6147 |
T6145 |
arg1Of |
promoter,the |
R4303 |
T6147 |
T6146 |
arg1Of |
promoter,ɛy |
R4304 |
T6151 |
T6148 |
arg2Of |
manner,in |
R4305 |
T6151 |
T6149 |
arg1Of |
manner,a |
R4306 |
T6151 |
T6150 |
arg1Of |
manner,CtBP2-independent |
R4307 |
T6153 |
T6152 |
arg1Of |
analysis,Deletion |
R4308 |
T6153 |
T6154 |
arg1Of |
analysis,of |
R4309 |
T6153 |
T6165 |
arg1Of |
analysis,defined |
R4310 |
T6157 |
T6154 |
arg2Of |
promoter,of |
R4311 |
T6157 |
T6155 |
arg1Of |
promoter,the |
R4312 |
T6157 |
T6156 |
arg1Of |
promoter,ɛy |
R4313 |
T6160 |
T6159 |
arg2Of |
shown,as |
R4314 |
T6160 |
T6161 |
arg1Of |
shown,in |
R4315 |
T6163 |
T6161 |
arg2Of |
2C,in |
R4316 |
T6163 |
T6162 |
arg1Of |
2C,Figure |
R4317 |
T6165 |
T6158 |
arg1Of |
defined,"," |
R4318 |
T6165 |
T6159 |
arg1Of |
defined,as |
R4319 |
T6165 |
T6164 |
arg1Of |
defined,"," |
R4320 |
T6167 |
T6165 |
arg2Of |
region,defined |
R4321 |
T6167 |
T6166 |
arg1Of |
region,a |
R4322 |
T6167 |
T6168 |
arg1Of |
region,( |
R4323 |
T6167 |
T6173 |
arg1Of |
region,within |
R4324 |
T6171 |
T6168 |
arg2Of |
−37,( |
R4325 |
T6171 |
T6169 |
arg1Of |
−37,−63 |
R4326 |
T6171 |
T6170 |
arg1Of |
−37,to |
R4327 |
T6172 |
T6168 |
arg3Of |
),( |
R4328 |
T6177 |
T6173 |
arg2Of |
promoter,within |
R4329 |
T6177 |
T6174 |
arg1Of |
promoter,the |
R4330 |
T6177 |
T6175 |
arg1Of |
promoter,ɛy |
R4331 |
T6177 |
T6176 |
arg1Of |
promoter,proximal |
R4332 |
T6177 |
T6178 |
arg1Of |
promoter,that |
R4333 |
T6177 |
T6179 |
arg1Of |
promoter,is |
R4334 |
T6177 |
T6180 |
arg1Of |
promoter,critical |
R4335 |
T6180 |
T6179 |
arg2Of |
critical,is |
R4336 |
T6180 |
T6181 |
arg1Of |
critical,for |
R4337 |
T6183 |
T6181 |
arg2Of |
repression,for |
R4338 |
T6183 |
T6182 |
arg1Of |
repression,Sox6 |
R4339 |
T6184 |
T6185 |
arg1Of |
Analysis,of |
R4340 |
T6184 |
T6189 |
arg1Of |
Analysis,reveals |
R4341 |
T6188 |
T6185 |
arg2Of |
region,of |
R4342 |
T6188 |
T6186 |
arg1Of |
region,this |
R4343 |
T6188 |
T6187 |
arg1Of |
region,short |
R4344 |
T6194 |
T6189 |
arg2Of |
sites,reveals |
R4345 |
T6194 |
T6190 |
arg1Of |
sites,two |
R4346 |
T6194 |
T6191 |
arg1Of |
sites,Sox/Sox6 |
R4347 |
T6194 |
T6192 |
arg1Of |
sites,consensus |
R4348 |
T6194 |
T6193 |
arg1Of |
sites,binding |
R4349 |
T6194 |
T6195 |
arg1Of |
sites,[ |
R4350 |
T6194 |
T6198 |
arg1Of |
sites,( |
R4351 |
T6196 |
T6195 |
arg2Of |
5,[ |
R4352 |
T6197 |
T6195 |
arg3Of |
],[ |
R4353 |
T6200 |
T6198 |
arg2Of |
3A,( |
R4354 |
T6200 |
T6199 |
arg1Of |
3A,Figure |
R4355 |
T6201 |
T6198 |
arg3Of |
),( |
R44 |
T254 |
T252 |
arg1Of |
Globin,Silences |
R45 |
T254 |
T253 |
arg1Of |
Globin,Epsilon |
R46 |
T255 |
T254 |
arg1Of |
Expression,Globin |
R47 |
T255 |
T256 |
arg1Of |
Expression,in |
R48 |
T258 |
T256 |
arg2Of |
Erythropoiesis,in |
R49 |
T258 |
T257 |
arg1Of |
Erythropoiesis,Definitive |
R50 |
T259 |
T260 |
arg1Of |
Sox6,is |
R5002 |
T7433 |
T7434 |
arg1Of |
EMSA,and |
R5003 |
T7434 |
T7441 |
arg1Of |
and,Binds |
R5004 |
T7437 |
T7435 |
arg1Of |
Show,ChIP |
R5005 |
T7437 |
T7436 |
arg1Of |
Show,Assays |
R5006 |
T7439 |
T7434 |
arg2Of |
Sox6,and |
R5007 |
T7439 |
T7437 |
arg1Of |
Sox6,Show |
R5008 |
T7439 |
T7438 |
arg1Of |
Sox6,that |
R5009 |
T7441 |
T7440 |
arg1Of |
Binds,Directly |
R5010 |
T7441 |
T7442 |
arg1Of |
Binds,to |
R5011 |
T7445 |
T7442 |
arg2Of |
Promoter,to |
R5012 |
T7445 |
T7443 |
arg1Of |
Promoter,the |
R5013 |
T7445 |
T7444 |
arg1Of |
Promoter,ɛy |
R5014 |
T7446 |
T7447 |
arg1Of |
Sox6,might |
R5015 |
T7446 |
T7448 |
arg1Of |
Sox6,repress |
R5016 |
T7446 |
T7463 |
arg1Of |
Sox6,regulating |
R5017 |
T7448 |
T7447 |
arg2Of |
repress,might |
R5018 |
T7448 |
T7452 |
arg1Of |
repress,"," |
R5019 |
T7448 |
T7454 |
arg1Of |
repress,through |
R5020 |
T7448 |
T7462 |
arg1Of |
repress,by |
R5021 |
T7451 |
T7448 |
arg2Of |
promoter,repress |
R5022 |
T7451 |
T7449 |
arg1Of |
promoter,the |
R5023 |
T7451 |
T7450 |
arg1Of |
promoter,ɛy |
R5024 |
T7454 |
T7461 |
arg1Of |
through,or |
R5025 |
T7457 |
T7454 |
arg2Of |
contact,through |
R5026 |
T7457 |
T7455 |
arg1Of |
contact,direct |
R5027 |
T7457 |
T7456 |
arg1Of |
contact,physical |
R5028 |
T7457 |
T7458 |
arg1Of |
contact,with |
R5029 |
T7460 |
T7458 |
arg2Of |
promoter,with |
R5030 |
T7460 |
T7459 |
arg1Of |
promoter,the |
R5031 |
T7461 |
T7453 |
arg1Of |
or,either |
R5032 |
T7462 |
T7461 |
arg2Of |
by,or |
R5033 |
T7463 |
T7462 |
arg2Of |
regulating,by |
R5034 |
T7464 |
T7463 |
arg2Of |
intermediates,regulating |
R5035 |
T7464 |
T7465 |
arg1Of |
intermediates,affecting |
R5036 |
T7468 |
T7465 |
arg2Of |
promoter,affecting |
R5037 |
T7468 |
T7466 |
arg1Of |
promoter,the |
R5038 |
T7468 |
T7467 |
arg1Of |
promoter,ɛy |
R5039 |
T7470 |
T7469 |
arg1Of |
investigate,To |
R5040 |
T7472 |
T7473 |
arg1Of |
Sox6,is |
R5041 |
T7472 |
T7475 |
arg2Of |
Sox6,associated |
R5042 |
T7475 |
T7470 |
arg2Of |
associated,investigate |
R5043 |
T7475 |
T7471 |
arg1Of |
associated,whether |
R5044 |
T7475 |
T7473 |
arg2Of |
associated,is |
R5045 |
T7475 |
T7474 |
arg1Of |
associated,directly |
R5046 |
T7475 |
T7476 |
arg1Of |
associated,with |
R5047 |
T7479 |
T7476 |
arg2Of |
promoter,with |
R5048 |
T7479 |
T7477 |
arg1Of |
promoter,the |
R5049 |
T7479 |
T7478 |
arg1Of |
promoter,ɛy |
R5050 |
T7481 |
T7470 |
arg1Of |
we,investigate |
R5051 |
T7481 |
T7483 |
arg1Of |
we,performed |
R5052 |
T7481 |
T7491 |
arg1Of |
we,using |
R5053 |
T7483 |
T7469 |
modOf |
performed,To |
R5054 |
T7483 |
T7480 |
arg1Of |
performed,"," |
R5055 |
T7483 |
T7482 |
arg1Of |
performed,first |
R5056 |
T7483 |
T7491 |
modOf |
performed,using |
R5057 |
T7487 |
T7483 |
arg2Of |
assays,performed |
R5058 |
T7487 |
T7484 |
arg1Of |
assays,electrophoretic |
R5059 |
T7487 |
T7485 |
arg1Of |
assays,mobility |
R5060 |
T7487 |
T7486 |
arg1Of |
assays,shift |
R5061 |
T7487 |
T7488 |
arg1Of |
assays,( |
R5062 |
T7489 |
T7488 |
arg2Of |
EMSA,( |
R5063 |
T7490 |
T7488 |
arg3Of |
),( |
R5064 |
T7494 |
T7491 |
arg2Of |
Sox6,using |
R5065 |
T7494 |
T7492 |
arg1Of |
Sox6,a |
R5066 |
T7494 |
T7493 |
arg1Of |
Sox6,c-Myc-tagged |
R5067 |
T7494 |
T7495 |
arg1Of |
Sox6,in |
R5068 |
T7501 |
T7500 |
arg1Of |
vitro,in |
R5069 |
T7502 |
T7495 |
arg2Of |
system,in |
R5070 |
T7502 |
T7496 |
arg1Of |
system,a |
R5071 |
T7502 |
T7497 |
arg1Of |
system,reticulocyte |
R5072 |
T7502 |
T7498 |
arg1Of |
system,lysate-based |
R5073 |
T7502 |
T7499 |
arg1Of |
system,transcription/translation |
R5074 |
T7502 |
T7501 |
arg1Of |
system,vitro |
R5075 |
T7504 |
T7503 |
arg1Of |
probes,The |
R5076 |
T7504 |
T7505 |
arg2Of |
probes,used |
R5077 |
T7504 |
T7506 |
arg1Of |
probes,are |
R5078 |
T7504 |
T7507 |
arg2Of |
probes,listed |
R5079 |
T7507 |
T7506 |
arg2Of |
listed,are |
R5080 |
T7507 |
T7508 |
arg1Of |
listed,in |
R5081 |
T7510 |
T7508 |
arg2Of |
3A,in |
R5082 |
T7510 |
T7509 |
arg1Of |
3A,Figure |
R5083 |
T7513 |
T7512 |
arg1Of |
pair,36–base |
R5084 |
T7513 |
T7514 |
arg1Of |
pair,( |
R5085 |
T7515 |
T7514 |
arg2Of |
bp,( |
R5086 |
T7516 |
T7514 |
arg3Of |
),( |
R5087 |
T7518 |
T7511 |
arg1Of |
probe,The |
R5088 |
T7518 |
T7513 |
arg1Of |
probe,pair |
R5089 |
T7518 |
T7517 |
arg1Of |
probe,WT |
R5090 |
T7518 |
T7519 |
arg1Of |
probe,corresponds |
R5091 |
T7519 |
T7520 |
arg1Of |
corresponds,to |
R5092 |
T7523 |
T7520 |
arg2Of |
region,to |
R5093 |
T7523 |
T7521 |
arg1Of |
region,the |
R5094 |
T7523 |
T7522 |
arg1Of |
region,critical |
R5095 |
T7523 |
T7524 |
arg1Of |
region,of |
R5096 |
T7527 |
T7524 |
arg2Of |
promoter,of |
R5097 |
T7527 |
T7525 |
arg1Of |
promoter,the |
R5098 |
T7527 |
T7526 |
arg1Of |
promoter,ɛy |
R5099 |
T7527 |
T7528 |
arg2Of |
promoter,defined |
R51 |
T262 |
T260 |
arg2Of |
member,is |
R5100 |
T7528 |
T7529 |
arg1Of |
defined,in |
R5101 |
T7533 |
T7529 |
arg2Of |
analyses,in |
R5102 |
T7533 |
T7530 |
arg1Of |
analyses,our |
R5103 |
T7533 |
T7531 |
arg1Of |
analyses,promoter |
R5104 |
T7533 |
T7532 |
arg1Of |
analyses,deletion |
R5105 |
T7535 |
T7534 |
arg1Of |
probe,This |
R5106 |
T7535 |
T7536 |
arg1Of |
probe,contains |
R5107 |
T7541 |
T7536 |
arg2Of |
sites,contains |
R5108 |
T7541 |
T7537 |
arg1Of |
sites,two |
R5109 |
T7541 |
T7538 |
arg1Of |
sites,consensus |
R5110 |
T7541 |
T7539 |
arg1Of |
sites,Sox/Sox6 |
R5111 |
T7541 |
T7540 |
arg1Of |
sites,binding |
R5112 |
T7543 |
T7542 |
arg1Of |
included,Also |
R5113 |
T7543 |
T7544 |
arg1Of |
included,in |
R5114 |
T7543 |
T7547 |
arg2Of |
included,are |
R5115 |
T7643 |
T7641 |
arg2Of |
probe,to |
R5116 |
T7643 |
T7642 |
arg1Of |
probe,the |
R5117 |
T7647 |
T7645 |
arg1Of |
Sox6,an |
R5118 |
T7647 |
T7646 |
arg1Of |
Sox6,HA-tagged |
R5119 |
T7647 |
T7648 |
arg1Of |
Sox6,was |
R5120 |
T7647 |
T7649 |
arg2Of |
Sox6,used |
R5121 |
T7649 |
T7630 |
modOf |
used,To |
R5122 |
T7649 |
T7644 |
arg1Of |
used,"," |
R5123 |
T7649 |
T7648 |
arg2Of |
used,was |
R5124 |
T7649 |
T7650 |
arg1Of |
used,in |
R5125 |
T7652 |
T7650 |
arg2Of |
EMSA,in |
R5126 |
T7652 |
T7651 |
arg1Of |
EMSA,another |
R5127 |
T7652 |
T7653 |
arg1Of |
EMSA,that |
R5128 |
T7652 |
T7654 |
arg1Of |
EMSA,confirmed |
R5129 |
T7656 |
T7654 |
arg2Of |
results,confirmed |
R5130 |
T7656 |
T7655 |
arg1Of |
results,these |
R5131 |
T7656 |
T7657 |
arg1Of |
results,( |
R5132 |
T7659 |
T7657 |
arg2Of |
3C,( |
R5133 |
T7659 |
T7658 |
arg1Of |
3C,Figure |
R5134 |
T7660 |
T7657 |
arg3Of |
),( |
R5135 |
T7664 |
T7663 |
arg1Of |
extracts,nuclear |
R5136 |
T7546 |
T7544 |
arg2Of |
EMSA,in |
R5137 |
T7546 |
T7545 |
arg1Of |
EMSA,our |
R5138 |
T7664 |
T7665 |
arg1Of |
extracts,from |
R5139 |
T7664 |
T7668 |
arg1Of |
extracts,were |
R5140 |
T7664 |
T7669 |
arg2Of |
extracts,used |
R5141 |
T7550 |
T7543 |
arg2Of |
probes,included |
R5142 |
T7550 |
T7547 |
arg1Of |
probes,are |
R5143 |
T7550 |
T7548 |
arg1Of |
probes,three |
R5144 |
T7550 |
T7549 |
arg2Of |
probes,mutated |
R5145 |
T7550 |
T7551 |
arg1Of |
probes,that |
R5146 |
T7550 |
T7552 |
arg1Of |
probes,are |
R5147 |
T7667 |
T7665 |
arg2Of |
cells,from |
R5148 |
T7552 |
T7553 |
arg1Of |
are,"," |
R5149 |
T7552 |
T7554 |
arg1Of |
are,either |
R5150 |
T7555 |
T7556 |
arg1Of |
truncated,( |
R5151 |
T7555 |
T7560 |
arg1Of |
truncated,or |
R5152 |
T7557 |
T7556 |
arg2Of |
M1,( |
R5153 |
T7558 |
T7556 |
arg3Of |
),( |
R5154 |
T7560 |
T7552 |
arg2Of |
or,are |
R5155 |
T7560 |
T7559 |
arg1Of |
or,"," |
R5156 |
T7560 |
T7567 |
arg1Of |
or,in |
R5157 |
T7667 |
T7666 |
arg1Of |
cells,MEL |
R5158 |
T7563 |
T7564 |
arg1Of |
M2,and |
R5159 |
T7669 |
T7661 |
arg1Of |
used,Next |
R5160 |
T7564 |
T7560 |
arg2Of |
and,or |
R5161 |
T7564 |
T7561 |
arg1Of |
and,mutated |
R5162 |
T7564 |
T7562 |
arg2Of |
and,( |
R5163 |
T7565 |
T7564 |
arg2Of |
M3,and |
R5164 |
T7566 |
T7562 |
arg3Of |
),( |
R5165 |
T7669 |
T7662 |
arg1Of |
used,"," |
R5166 |
T7669 |
T7668 |
arg2Of |
used,were |
R5167 |
T7669 |
T7670 |
arg1Of |
used,in |
R5168 |
T7570 |
T7567 |
arg2Of |
sites,in |
R5169 |
T7570 |
T7568 |
arg1Of |
sites,Sox/Sox6 |
R5170 |
T7570 |
T7569 |
arg1Of |
sites,binding |
R5171 |
T7570 |
T7571 |
arg1Of |
sites,( |
R5172 |
T7671 |
T7670 |
arg2Of |
EMSA,in |
R5173 |
T7573 |
T7571 |
arg2Of |
3A,( |
R5174 |
T7573 |
T7572 |
arg1Of |
3A,Figure |
R5175 |
T7574 |
T7571 |
arg3Of |
),( |
R5176 |
T7575 |
T7576 |
arg1Of |
Sox6,is |
R5177 |
T7575 |
T7577 |
arg1Of |
Sox6,able |
R5178 |
T7575 |
T7580 |
arg1Of |
Sox6,associate |
R5179 |
T7671 |
T7672 |
arg1Of |
EMSA,employing |
R5180 |
T7577 |
T7576 |
arg2Of |
able,is |
R5181 |
T7676 |
T7672 |
arg2Of |
probe,employing |
R5182 |
T7580 |
T7577 |
arg2Of |
associate,able |
R5183 |
T7580 |
T7578 |
arg1Of |
associate,to |
R5184 |
T7580 |
T7579 |
arg1Of |
associate,physically |
R5185 |
T7580 |
T7581 |
arg1Of |
associate,with |
R5186 |
T7584 |
T7581 |
arg2Of |
region,with |
R5187 |
T7584 |
T7582 |
arg1Of |
region,the |
R5188 |
T7584 |
T7583 |
arg1Of |
region,36-bp |
R5189 |
T7584 |
T7585 |
arg1Of |
region,( |
R5190 |
T7584 |
T7589 |
arg1Of |
region,within |
R5191 |
T7676 |
T7673 |
arg1Of |
probe,the |
R5192 |
T7587 |
T7585 |
arg2Of |
3B,( |
R5193 |
T7587 |
T7586 |
arg1Of |
3B,Figure |
R5194 |
T7676 |
T7674 |
arg1Of |
probe,same |
R5195 |
T7588 |
T7585 |
arg3Of |
),( |
R5196 |
T7676 |
T7675 |
arg1Of |
probe,36-bp |
R5197 |
T7678 |
T7677 |
arg1Of |
cells,MEL |
R5198 |
T7592 |
T7589 |
arg2Of |
promoter,within |
R5199 |
T7592 |
T7590 |
arg1Of |
promoter,the |
R52 |
T262 |
T261 |
arg1Of |
member,a |
R5200 |
T7592 |
T7591 |
arg1Of |
promoter,ɛy |
R5201 |
T7592 |
T7593 |
arg2Of |
promoter,defined |
R5202 |
T7598 |
T7593 |
arg1Of |
experiments,defined |
R5203 |
T7598 |
T7594 |
arg2Of |
experiments,by |
R5204 |
T7598 |
T7595 |
arg1Of |
experiments,the |
R5205 |
T7598 |
T7596 |
arg1Of |
experiments,deletion |
R5206 |
T7598 |
T7597 |
arg1Of |
experiments,analysis |
R5207 |
T7598 |
T7599 |
arg1Of |
experiments,( |
R5208 |
T7678 |
T7679 |
arg1Of |
cells,"," |
R5209 |
T7678 |
T7686 |
arg1Of |
cells,express |
R5210 |
T7601 |
T7599 |
arg2Of |
2C,( |
R5211 |
T7601 |
T7600 |
arg1Of |
2C,Figure |
R5212 |
T7602 |
T7599 |
arg3Of |
),( |
R5213 |
T7678 |
T7693 |
arg1Of |
cells,ɛy |
R5214 |
T7684 |
T7679 |
arg2Of |
line,"," |
R5215 |
T7605 |
T7603 |
arg1Of |
probe,The |
R5216 |
T7605 |
T7604 |
arg1Of |
probe,36-bp |
R5217 |
T7605 |
T7606 |
arg1Of |
probe,was |
R5218 |
T7605 |
T7607 |
arg2Of |
probe,shifted |
R5219 |
T7607 |
T7606 |
arg2Of |
shifted,was |
R5220 |
T7684 |
T7680 |
arg1Of |
line,a |
R5221 |
T7684 |
T7681 |
arg1Of |
line,murine |
R5222 |
T7684 |
T7682 |
arg1Of |
line,erythroleukemic |
R5223 |
T7684 |
T7683 |
arg1Of |
line,cell |
R5224 |
T7686 |
T7691 |
arg1Of |
express,but |
R5225 |
T7612 |
T7607 |
arg1Of |
protein,shifted |
R5226 |
T7612 |
T7608 |
arg2Of |
protein,by |
R5227 |
T7612 |
T7609 |
arg1Of |
protein,the |
R5228 |
T7612 |
T7610 |
arg2Of |
protein,tagged |
R5229 |
T7612 |
T7611 |
arg1Of |
protein,Sox6 |
R5230 |
T7616 |
T7617 |
arg1Of |
c-Myc,and |
R5231 |
T7689 |
T7686 |
arg2Of |
globins,express |
R5232 |
T7617 |
T7615 |
arg1Of |
and,both |
R5233 |
T7618 |
T7617 |
arg2Of |
Sox6,and |
R5234 |
T7619 |
T7616 |
arg1Of |
antibodies,c-Myc |
R5235 |
T7619 |
T7618 |
arg1Of |
antibodies,Sox6 |
R5236 |
T7619 |
T7620 |
arg1Of |
antibodies,supershift |
R5237 |
T7620 |
T7613 |
arg1Of |
supershift,Moreover |
R5238 |
T7620 |
T7614 |
arg1Of |
supershift,"," |
R5239 |
T7620 |
T7623 |
arg1Of |
supershift,"," |
R5240 |
T7620 |
T7624 |
modOf |
supershift,indicating |
R5241 |
T7622 |
T7620 |
arg2Of |
band,supershift |
R5242 |
T7622 |
T7621 |
arg1Of |
band,the |
R5243 |
T7689 |
T7687 |
arg1Of |
globins,adult |
R5244 |
T7689 |
T7688 |
arg1Of |
globins,β |
R5245 |
T7691 |
T7685 |
arg1Of |
but,"," |
R5246 |
T7627 |
T7626 |
arg1Of |
binding,the |
R5247 |
T7627 |
T7628 |
arg1Of |
binding,is |
R5248 |
T7627 |
T7629 |
arg1Of |
binding,Sox6-specific |
R5249 |
T7628 |
T7624 |
arg2Of |
is,indicating |
R5250 |
T7628 |
T7625 |
arg1Of |
is,that |
R5251 |
T7629 |
T7628 |
arg2Of |
Sox6-specific,is |
R5252 |
T7631 |
T7630 |
arg1Of |
rule,To |
R5253 |
T7631 |
T7632 |
arg1Of |
rule,out |
R5254 |
T7691 |
T7690 |
arg1Of |
but,"," |
R5255 |
T7634 |
T7631 |
arg2Of |
possibility,rule |
R5256 |
T7634 |
T7633 |
arg1Of |
possibility,the |
R5257 |
T7691 |
T7692 |
arg1Of |
but,not |
R5258 |
T7693 |
T7691 |
arg2Of |
ɛy,but |
R5259 |
T7638 |
T7636 |
arg1Of |
tag,the |
R5260 |
T7638 |
T7637 |
arg1Of |
tag,c-Myc |
R5261 |
T7639 |
T7638 |
arg1Of |
itself,tag |
R5262 |
T7639 |
T7640 |
arg1Of |
itself,binds |
R5263 |
T7640 |
T7634 |
arg2Of |
binds,possibility |
R5264 |
T7640 |
T7635 |
arg1Of |
binds,that |
R5265 |
T7640 |
T7641 |
arg1Of |
binds,to |
R5266 |
T7693 |
T7694 |
arg1Of |
ɛy,[ |
R5267 |
T7695 |
T7694 |
arg2Of |
33,[ |
R5268 |
T7696 |
T7694 |
arg3Of |
],[ |
R5269 |
T7697 |
T7699 |
arg1Of |
Sox6,binds |
R5270 |
T7699 |
T7698 |
arg1Of |
binds,directly |
R5271 |
T7699 |
T7700 |
arg1Of |
binds,to |
R5272 |
T7703 |
T7700 |
arg2Of |
sequence,to |
R5273 |
T7742 |
T7738 |
arg2Of |
sites,of |
R5274 |
T7742 |
T7739 |
arg1Of |
sites,putative |
R5275 |
T7742 |
T7740 |
arg1Of |
sites,Sox/Sox6 |
R5276 |
T7742 |
T7741 |
arg1Of |
sites,binding |
R5277 |
T7742 |
T7743 |
arg1Of |
sites,( |
R5278 |
T7744 |
T7745 |
arg1Of |
M1,and |
R5279 |
T7745 |
T7743 |
arg2Of |
and,( |
R5280 |
T7746 |
T7745 |
arg2Of |
M3,and |
R5281 |
T7703 |
T7701 |
arg1Of |
sequence,this |
R5282 |
T7747 |
T7743 |
arg3Of |
),( |
R5283 |
T7703 |
T7702 |
arg1Of |
sequence,DNA |
R5284 |
T7703 |
T7704 |
arg1Of |
sequence,in |
R5285 |
T7706 |
T7704 |
arg2Of |
cells,in |
R5286 |
T7750 |
T7748 |
arg2Of |
ability,abolish |
R5287 |
T7750 |
T7749 |
arg1Of |
ability,their |
R5288 |
T7750 |
T7751 |
modOf |
ability,to |
R5289 |
T7752 |
T7751 |
arg1Of |
compete,to |
R5290 |
T7752 |
T7753 |
arg1Of |
compete,in |
R5291 |
T7706 |
T7705 |
arg1Of |
cells,MEL |
R5292 |
T7706 |
T7707 |
arg1Of |
cells,( |
R5293 |
T7709 |
T7707 |
arg2Of |
3D,( |
R5294 |
T7754 |
T7753 |
arg2Of |
EMSA,in |
R5295 |
T7754 |
T7755 |
arg1Of |
EMSA,( |
R5296 |
T7709 |
T7708 |
arg1Of |
3D,Figure |
R5297 |
T7757 |
T7755 |
arg2Of |
3E,( |
R5298 |
T7757 |
T7756 |
arg1Of |
3E,Figure |
R5299 |
T7758 |
T7755 |
arg3Of |
),( |
R53 |
T262 |
T263 |
arg1Of |
member,of |
R5300 |
T7710 |
T7707 |
arg3Of |
),( |
R5301 |
T7762 |
T7759 |
arg1Of |
probe,The |
R5302 |
T7762 |
T7760 |
arg1Of |
probe,M2 |
R5303 |
T7762 |
T7761 |
arg1Of |
probe,mutant |
R5304 |
T7762 |
T7763 |
arg1Of |
probe,may |
R5305 |
T7762 |
T7764 |
arg1Of |
probe,compete |
R5306 |
T7764 |
T7763 |
arg2Of |
compete,may |
R5307 |
T7764 |
T7765 |
arg1Of |
compete,partially |
R5308 |
T7764 |
T7766 |
arg1Of |
compete,with |
R5309 |
T7716 |
T7711 |
arg1Of |
sites,The |
R5310 |
T7768 |
T7766 |
arg2Of |
binding,with |
R5311 |
T7768 |
T7767 |
arg1Of |
binding,WT |
R5312 |
T7770 |
T7769 |
arg1Of |
investigate,To |
R5313 |
T7773 |
T7770 |
arg2Of |
significance,investigate |
R5314 |
T7773 |
T7771 |
arg1Of |
significance,the |
R5315 |
T7773 |
T7772 |
arg1Of |
significance,functional |
R5316 |
T7773 |
T7774 |
arg1Of |
significance,of |
R5317 |
T7716 |
T7712 |
arg1Of |
sites,intact |
R5318 |
T7716 |
T7713 |
arg1Of |
sites,consensus |
R5319 |
T7716 |
T7714 |
arg1Of |
sites,Sox/Sox6 |
R5320 |
T7716 |
T7715 |
arg1Of |
sites,binding |
R5321 |
T7716 |
T7717 |
arg1Of |
sites,of |
R5322 |
T7779 |
T7774 |
arg2Of |
sites,of |
R5323 |
T7779 |
T7775 |
arg1Of |
sites,the |
R5324 |
T7779 |
T7776 |
arg1Of |
sites,intact |
R5325 |
T7779 |
T7777 |
arg1Of |
sites,Sox/Sox6 |
R5326 |
T7779 |
T7778 |
arg1Of |
sites,binding |
R5327 |
T7716 |
T7721 |
arg1Of |
sites,are |
R5328 |
T7716 |
T7722 |
arg2Of |
sites,required |
R5329 |
T7720 |
T7717 |
arg2Of |
probe,of |
R5330 |
T7785 |
T7781 |
arg1Of |
constructs,the |
R5331 |
T7785 |
T7782 |
arg1Of |
constructs,ɛy |
R5332 |
T7785 |
T7783 |
arg1Of |
constructs,promoter |
R5333 |
T7785 |
T7784 |
arg1Of |
constructs,reporter |
R5334 |
T7785 |
T7786 |
arg1Of |
constructs,with |
R5335 |
T7785 |
T7791 |
arg1Of |
constructs,were |
R5336 |
T7785 |
T7792 |
arg2Of |
constructs,co-transfected |
R5337 |
T7790 |
T7786 |
arg2Of |
sites,with |
R5338 |
T7790 |
T7787 |
arg2Of |
sites,mutagenized |
R5339 |
T7790 |
T7788 |
arg1Of |
sites,Sox/Sox6 |
R5340 |
T7790 |
T7789 |
arg1Of |
sites,binding |
R5341 |
T7720 |
T7718 |
arg1Of |
probe,the |
R5342 |
T7792 |
T7769 |
modOf |
co-transfected,To |
R5343 |
T7792 |
T7780 |
arg1Of |
co-transfected,"," |
R5344 |
T7792 |
T7791 |
arg2Of |
co-transfected,were |
R5345 |
T7792 |
T7793 |
arg1Of |
co-transfected,with |
R5346 |
T7720 |
T7719 |
arg1Of |
probe,DNA |
R5347 |
T7722 |
T7721 |
arg2Of |
required,are |
R5348 |
T7797 |
T7793 |
arg2Of |
vector,with |
R5349 |
T7797 |
T7794 |
arg1Of |
vector,the |
R5350 |
T7797 |
T7795 |
arg1Of |
vector,Sox6 |
R5351 |
T7797 |
T7796 |
arg1Of |
vector,overexpression |
R5352 |
T7797 |
T7798 |
arg1Of |
vector,into |
R5353 |
T7800 |
T7798 |
arg2Of |
cells,into |
R5354 |
T7800 |
T7799 |
arg1Of |
cells,GM979 |
R5355 |
T7801 |
T7802 |
arg1Of |
Consistent,with |
R5356 |
T7722 |
T7723 |
arg1Of |
required,for |
R5357 |
T7722 |
T7726 |
arg1Of |
required,"," |
R5358 |
T7805 |
T7802 |
arg2Of |
results,with |
R5359 |
T7805 |
T7803 |
arg1Of |
results,the |
R5360 |
T7805 |
T7804 |
arg1Of |
results,EMSA |
R5361 |
T7722 |
T7727 |
arg1Of |
required,as |
R5362 |
T7725 |
T7723 |
arg2Of |
binding,for |
R5363 |
T7725 |
T7724 |
arg1Of |
binding,the |
R5364 |
T7812 |
T7807 |
arg1Of |
constructs,the |
R5365 |
T7812 |
T7808 |
arg1Of |
constructs,mutant |
R5366 |
T7812 |
T7809 |
arg1Of |
constructs,ɛy |
R5367 |
T7812 |
T7810 |
arg1Of |
constructs,promoter |
R5368 |
T7812 |
T7811 |
arg1Of |
constructs,reporter |
R5369 |
T7812 |
T7813 |
arg1Of |
constructs,( |
R5370 |
T7812 |
T7824 |
arg1Of |
constructs,do |
R5371 |
T7812 |
T7826 |
arg1Of |
constructs,result |
R5372 |
T7814 |
T7813 |
arg2Of |
with,( |
R5373 |
T7728 |
T7727 |
arg2Of |
shown,as |
R5374 |
T7728 |
T7729 |
arg1Of |
shown,in |
R5375 |
T7732 |
T7729 |
arg2Of |
assay,in |
R5376 |
T7821 |
T7814 |
arg2Of |
sites,with |
R5377 |
T7821 |
T7815 |
arg1Of |
sites,either |
R5378 |
T7821 |
T7816 |
arg1Of |
sites,one |
R5379 |
T7821 |
T7817 |
arg1Of |
sites,or |
R5380 |
T7821 |
T7818 |
arg1Of |
sites,both |
R5381 |
T7821 |
T7819 |
arg1Of |
sites,Sox/Sox6 |
R5382 |
T7821 |
T7820 |
arg1Of |
sites,binding |
R5383 |
T7821 |
T7822 |
arg2Of |
sites,mutagenized |
R5384 |
T7823 |
T7813 |
arg3Of |
),( |
R5385 |
T7826 |
T7801 |
arg1Of |
result,Consistent |
R5386 |
T7826 |
T7806 |
arg1Of |
result,"," |
R5387 |
T7826 |
T7824 |
arg2Of |
result,do |
R5388 |
T7826 |
T7825 |
arg1Of |
result,not |
R5389 |
T7826 |
T7827 |
arg1Of |
result,in |
R5390 |
T7830 |
T7827 |
arg2Of |
repression,in |
R5391 |
T7732 |
T7730 |
arg1Of |
assay,the |
R5392 |
T7732 |
T7731 |
arg1Of |
assay,competition |
R5393 |
T7732 |
T7733 |
arg1Of |
assay,( |
R5394 |
T7735 |
T7733 |
arg2Of |
3E,( |
R5395 |
T7830 |
T7828 |
arg1Of |
repression,significant |
R5396 |
T7830 |
T7829 |
arg1Of |
repression,promoter |
R5397 |
T7830 |
T7831 |
arg1Of |
repression,in |
R5398 |
T7833 |
T7831 |
arg2Of |
studies,in |
R5399 |
T7833 |
T7832 |
arg1Of |
studies,transfection |
R54 |
T262 |
T269 |
arg1Of |
member,that |
R5400 |
T7833 |
T7834 |
arg1Of |
studies,( |
R5401 |
T7836 |
T7834 |
arg2Of |
3F,( |
R5402 |
T7836 |
T7835 |
arg1Of |
3F,Figure |
R5403 |
T7735 |
T7734 |
arg1Of |
3E,Figure |
R5404 |
T7736 |
T7733 |
arg3Of |
),( |
R5405 |
T7737 |
T7738 |
arg1Of |
Ablation,of |
R5406 |
T7737 |
T7748 |
arg1Of |
Ablation,abolish |
R5407 |
T7935 |
T7933 |
arg1Of |
data,The |
R5408 |
T7837 |
T7834 |
arg3Of |
),( |
R5409 |
T7935 |
T7934 |
arg1Of |
data,above |
R5410 |
T7841 |
T7840 |
arg1Of |
sites,both |
R5411 |
T7841 |
T7842 |
arg1Of |
sites,are |
R5412 |
T7841 |
T7843 |
arg2Of |
sites,required |
R5413 |
T7935 |
T7936 |
arg1Of |
data,( |
R5414 |
T7935 |
T7943 |
arg1Of |
data,indicate |
R5415 |
T7843 |
T7838 |
arg1Of |
required,Thus |
R5416 |
T7843 |
T7839 |
arg1Of |
required,"," |
R5417 |
T7843 |
T7842 |
arg2Of |
required,are |
R5418 |
T7843 |
T7844 |
arg1Of |
required,for |
R5419 |
T7843 |
T7854 |
arg1Of |
required,to |
R5420 |
T7844 |
T7852 |
arg1Of |
for,but |
R5421 |
T7938 |
T7939 |
arg1Of |
3,and |
R5422 |
T7846 |
T7844 |
arg2Of |
repression,for |
R5423 |
T7846 |
T7845 |
arg1Of |
repression,maximal |
R5424 |
T7846 |
T7847 |
arg1Of |
repression,of |
R5425 |
T7846 |
T7849 |
arg1Of |
repression,by |
R5426 |
T7848 |
T7847 |
arg2Of |
ɛy,of |
R5427 |
T7850 |
T7849 |
arg2Of |
Sox6,by |
R5428 |
T7939 |
T7936 |
arg2Of |
and,( |
R5429 |
T7852 |
T7851 |
arg1Of |
but,"," |
R5430 |
T7939 |
T7937 |
arg1Of |
and,Figures |
R5431 |
T7854 |
T7852 |
arg2Of |
to,but |
R5432 |
T7854 |
T7853 |
arg1Of |
to,not |
R5433 |
T7940 |
T7939 |
arg2Of |
4,and |
R5434 |
T7857 |
T7854 |
arg2Of |
degree,to |
R5435 |
T7857 |
T7855 |
arg1Of |
degree,the |
R5436 |
T7857 |
T7856 |
arg1Of |
degree,same |
R5437 |
T7941 |
T7936 |
arg3Of |
),( |
R5438 |
T7858 |
T7860 |
arg1Of |
We,tested |
R5439 |
T7860 |
T7859 |
arg1Of |
tested,also |
R5440 |
T7943 |
T7942 |
arg1Of |
indicate,clearly |
R5441 |
T7862 |
T7863 |
arg1Of |
Sox6,binds |
R5442 |
T7863 |
T7860 |
arg2Of |
binds,tested |
R5443 |
T7863 |
T7861 |
arg1Of |
binds,whether |
R5444 |
T7945 |
T7946 |
arg1Of |
Sox6,acts |
R5445 |
T7946 |
T7943 |
arg2Of |
acts,indicate |
R5446 |
T7863 |
T7864 |
arg1Of |
binds,to |
R5447 |
T7863 |
T7869 |
arg1Of |
binds,vivo |
R5448 |
T7946 |
T7944 |
arg1Of |
acts,that |
R5449 |
T7946 |
T7947 |
arg1Of |
acts,as |
R5450 |
T7867 |
T7864 |
arg2Of |
promoter,to |
R5451 |
T7867 |
T7865 |
arg1Of |
promoter,the |
R5452 |
T7867 |
T7866 |
arg1Of |
promoter,ɛy |
R5453 |
T7869 |
T7868 |
arg1Of |
vivo,in |
R5454 |
T7870 |
T7863 |
arg2Of |
using,binds |
R5455 |
T7872 |
T7870 |
arg2Of |
immunoprecipitation,using |
R5456 |
T7872 |
T7871 |
arg1Of |
immunoprecipitation,chromatin |
R5457 |
T7872 |
T7873 |
arg1Of |
immunoprecipitation,( |
R5458 |
T7872 |
T7876 |
arg1Of |
immunoprecipitation,( |
R5459 |
T7874 |
T7873 |
arg2Of |
ChIP,( |
R5460 |
T7946 |
T7954 |
arg1Of |
acts,by |
R5461 |
T7875 |
T7873 |
arg3Of |
),( |
R5462 |
T7949 |
T7947 |
arg2Of |
repressor,as |
R5463 |
T7877 |
T7876 |
arg2Of |
Figure,( |
R5464 |
T7877 |
T7878 |
arg1Of |
Figure,4 |
R5465 |
T7879 |
T7876 |
arg3Of |
),( |
R5466 |
T7949 |
T7948 |
arg1Of |
repressor,a |
R5467 |
T7882 |
T7880 |
arg1Of |
complex,The |
R5468 |
T7882 |
T7881 |
arg1Of |
complex,Sox6-containing |
R5469 |
T7882 |
T7883 |
arg1Of |
complex,was |
R5470 |
T7882 |
T7884 |
arg2Of |
complex,immunoprecipitated |
R5471 |
T7884 |
T7883 |
arg2Of |
immunoprecipitated,was |
R5472 |
T7884 |
T7885 |
arg1Of |
immunoprecipitated,from |
R5473 |
T7884 |
T7889 |
arg1Of |
immunoprecipitated,from |
R5474 |
T7949 |
T7950 |
arg1Of |
repressor,of |
R5475 |
T7885 |
T7888 |
arg1Of |
from,or |
R5476 |
T7953 |
T7950 |
arg2Of |
gene,of |
R5477 |
T7887 |
T7885 |
arg2Of |
cells,from |
R5478 |
T7887 |
T7886 |
arg1Of |
cells,MEL |
R5479 |
T7889 |
T7888 |
arg2Of |
from,or |
R5480 |
T7891 |
T7889 |
arg2Of |
cells,from |
R5481 |
T7891 |
T7890 |
arg1Of |
cells,liver |
R5482 |
T7891 |
T7892 |
arg1Of |
cells,of |
R5483 |
T7953 |
T7951 |
arg1Of |
gene,the |
R5484 |
T7953 |
T7952 |
arg1Of |
gene,ɛy |
R5485 |
T7956 |
T7954 |
arg2Of |
binding,by |
R5486 |
T7896 |
T7892 |
arg2Of |
mice,of |
R5487 |
T7896 |
T7893 |
arg1Of |
mice,15.5 |
R5488 |
T7896 |
T7894 |
arg1Of |
mice,dpc |
R5489 |
T7896 |
T7895 |
arg1Of |
mice,WT |
R5490 |
T7896 |
T7897 |
arg1Of |
mice,using |
R5491 |
T7956 |
T7955 |
arg1Of |
binding,directly |
R5492 |
T7956 |
T7957 |
arg1Of |
binding,to |
R5493 |
T7899 |
T7897 |
arg2Of |
antibody,using |
R5494 |
T7899 |
T7898 |
arg1Of |
antibody,Sox6 |
R5495 |
T7956 |
T7961 |
arg1Of |
binding,"," |
R5496 |
T7956 |
T7963 |
arg1Of |
binding,as |
R5497 |
T7960 |
T7957 |
arg2Of |
promoter,to |
R5498 |
T7902 |
T7900 |
arg1Of |
shows,Figure |
R5499 |
T7902 |
T7901 |
arg1Of |
shows,4 |
R55 |
T262 |
T270 |
arg1Of |
member,is |
R5500 |
T7902 |
T7903 |
arg1Of |
shows,that |
R5501 |
T7902 |
T7914 |
arg1Of |
shows,in |
R5502 |
T7960 |
T7958 |
arg1Of |
promoter,the |
R5503 |
T7907 |
T7904 |
arg1Of |
promoter,the |
R5504 |
T7907 |
T7905 |
arg1Of |
promoter,ɛy |
R5505 |
T7907 |
T7906 |
arg1Of |
promoter,proximal |
R5506 |
T7907 |
T7908 |
arg1Of |
promoter,is |
R5507 |
T7907 |
T7910 |
arg2Of |
promoter,immunoprecipitated |
R5508 |
T7960 |
T7959 |
arg1Of |
promoter,ɛy |
R5509 |
T7963 |
T7962 |
arg1Of |
as,probably |
R5510 |
T7910 |
T7903 |
arg2Of |
immunoprecipitated,that |
R5511 |
T7910 |
T7908 |
arg2Of |
immunoprecipitated,is |
R5512 |
T7910 |
T7909 |
arg1Of |
immunoprecipitated,readily |
R5513 |
T7910 |
T7911 |
arg1Of |
immunoprecipitated,with |
R5514 |
T7913 |
T7911 |
arg2Of |
antibody,with |
R5515 |
T7913 |
T7912 |
arg1Of |
antibody,Sox6 |
R5516 |
T7965 |
T7963 |
arg2Of |
dimer,as |
R5517 |
T7917 |
T7916 |
arg1Of |
cells,MEL |
R5518 |
T7917 |
T7918 |
arg1Of |
cells,and |
R5519 |
T7918 |
T7914 |
arg2Of |
and,in |
R5520 |
T7918 |
T7915 |
arg1Of |
and,both |
R5521 |
T7920 |
T7918 |
arg2Of |
cells,and |
R5522 |
T7920 |
T7919 |
arg1Of |
cells,liver |
R5523 |
T7965 |
T7964 |
arg1Of |
dimer,a |
R5524 |
T7922 |
T7921 |
arg1Of |
IgG,Normal |
R5525 |
T7922 |
T7923 |
arg1Of |
IgG,was |
R5526 |
T7922 |
T7924 |
arg2Of |
IgG,used |
R5528 |
T7924 |
T7923 |
arg2Of |
used,was |
R5529 |
T7924 |
T7925 |
arg1Of |
used,as |
R5530 |
T7928 |
T7925 |
arg2Of |
control,as |
R5531 |
T7928 |
T7926 |
arg1Of |
control,a |
R5532 |
T7928 |
T7927 |
arg1Of |
control,negative |
R5533 |
T7928 |
T7929 |
arg1Of |
control,( |
R5534 |
T7931 |
T7929 |
arg2Of |
4A,( |
R5535 |
T7931 |
T7930 |
arg1Of |
4A,Figure |
R5536 |
T7932 |
T7929 |
arg3Of |
),( |
R56 |
T262 |
T271 |
arg2Of |
member,defined |
R57 |
T268 |
T263 |
arg2Of |
family,of |
R58 |
T268 |
T264 |
arg1Of |
family,the |
R59 |
T268 |
T265 |
arg1Of |
family,Sox |
R60 |
T268 |
T266 |
arg1Of |
family,transcription |
R61 |
T268 |
T267 |
arg1Of |
family,factor |
R62 |
T271 |
T270 |
arg2Of |
defined,is |
R6272 |
T9131 |
T9129 |
arg1Of |
Expression,The |
R6273 |
T9131 |
T9130 |
arg1Of |
Expression,Persistent |
R6274 |
T9131 |
T9132 |
arg1Of |
Expression,of |
R6275 |
T9131 |
T9135 |
arg1Of |
Expression,in |
R6276 |
T9131 |
T9138 |
arg1Of |
Expression,Is |
R6277 |
T9131 |
T9140 |
arg1Of |
Expression,to |
R6278 |
T9134 |
T9132 |
arg2Of |
Globin,of |
R6279 |
T9134 |
T9133 |
arg1Of |
Globin,ɛy |
R6280 |
T9137 |
T9135 |
arg2Of |
Mice,in |
R6281 |
T9137 |
T9136 |
arg1Of |
Mice,Sox6-Deficient |
R6282 |
T9140 |
T9138 |
arg2Of |
to,Is |
R6283 |
T9140 |
T9139 |
arg1Of |
to,Due |
R6284 |
T9142 |
T9140 |
arg2Of |
Defect,to |
R6285 |
T9142 |
T9141 |
arg1Of |
Defect,a |
R6286 |
T9142 |
T9143 |
arg1Of |
Defect,in |
R6287 |
T9146 |
T9143 |
arg2Of |
Mechanism,in |
R6288 |
T9146 |
T9144 |
arg1Of |
Mechanism,the |
R6289 |
T9146 |
T9145 |
arg1Of |
Mechanism,ɛy-Gene–Silencing |
R6290 |
T9146 |
T9147 |
arg1Of |
Mechanism,in |
R6291 |
T9150 |
T9147 |
arg2Of |
Cells,in |
R6292 |
T9150 |
T9148 |
arg1Of |
Cells,Definitive |
R6293 |
T9150 |
T9149 |
arg1Of |
Cells,Erythroid |
R6294 |
T9156 |
T9153 |
arg1Of |
gene,the |
R6295 |
T9156 |
T9154 |
arg1Of |
gene,ɛy |
R6296 |
T9156 |
T9155 |
arg1Of |
gene,globin |
R6297 |
T9156 |
T9157 |
arg1Of |
gene,is |
R6298 |
T9156 |
T9159 |
arg2Of |
gene,expressed |
R6299 |
T9156 |
T9164 |
arg1Of |
gene,silenced |
R63 |
T279 |
T278 |
arg2Of |
HMG,( |
R6300 |
T9159 |
T9160 |
arg1Of |
expressed,in |
R6301 |
T9159 |
T9163 |
arg1Of |
expressed,and |
R6302 |
T9162 |
T9160 |
arg2Of |
erythrocytes,in |
R6303 |
T9162 |
T9161 |
arg1Of |
erythrocytes,primitive |
R6304 |
T9163 |
T9151 |
arg1Of |
and,Normally |
R6305 |
T9163 |
T9152 |
arg1Of |
and,"," |
R6306 |
T9163 |
T9157 |
arg2Of |
and,is |
R6307 |
T9163 |
T9158 |
arg1Of |
and,exclusively |
R6308 |
T9163 |
T9165 |
arg1Of |
and,in |
R6309 |
T9164 |
T9163 |
arg2Of |
silenced,and |
R6310 |
T9167 |
T9165 |
arg2Of |
erythrocytes,in |
R6311 |
T9167 |
T9166 |
arg1Of |
erythrocytes,definitive |
R6312 |
T9169 |
T9168 |
arg1Of |
determine,To |
R6313 |
T9173 |
T9171 |
arg1Of |
expression,the |
R6314 |
T9173 |
T9172 |
arg1Of |
expression,persistent |
R6315 |
T9173 |
T9174 |
arg1Of |
expression,of |
R6316 |
T9173 |
T9177 |
arg1Of |
expression,is |
R6317 |
T9173 |
T9178 |
arg1Of |
expression,due |
R6318 |
T9173 |
T9184 |
arg1Of |
expression,is |
R6319 |
T9173 |
T9185 |
arg1Of |
expression,due |
R6320 |
T9176 |
T9174 |
arg2Of |
globin,of |
R6321 |
T9176 |
T9175 |
arg1Of |
globin,ɛy |
R6322 |
T9177 |
T9183 |
arg1Of |
is,or |
R6323 |
T9178 |
T9177 |
arg2Of |
due,is |
R6324 |
T9178 |
T9179 |
arg1Of |
due,to |
R6325 |
T9182 |
T9179 |
arg2Of |
erythrocytes,to |
R6326 |
T9182 |
T9180 |
arg1Of |
erythrocytes,residual |
R6327 |
T9182 |
T9181 |
arg1Of |
erythrocytes,primitive |
R6328 |
T9183 |
T9169 |
arg2Of |
or,determine |
R6329 |
T9183 |
T9170 |
arg1Of |
or,whether |
R6330 |
T9184 |
T9183 |
arg2Of |
is,or |
R6331 |
T9185 |
T9184 |
arg2Of |
due,is |
R6332 |
T9185 |
T9186 |
arg1Of |
due,to |
R6333 |
T9188 |
T9186 |
arg2Of |
expression,to |
R6334 |
T9188 |
T9187 |
arg1Of |
expression,ectopic |
R6335 |
T9188 |
T9189 |
arg1Of |
expression,of |
R6336 |
T9188 |
T9192 |
arg1Of |
expression,in |
R6337 |
T9191 |
T9189 |
arg2Of |
globin,of |
R6338 |
T9191 |
T9190 |
arg1Of |
globin,ɛy |
R6339 |
T9194 |
T9192 |
arg2Of |
erythrocytes,in |
R6340 |
T9194 |
T9193 |
arg1Of |
erythrocytes,definitive |
R6341 |
T9196 |
T9197 |
arg1Of |
we,examined |
R6342 |
T9197 |
T9168 |
modOf |
examined,To |
R6343 |
T9197 |
T9195 |
arg1Of |
examined,"," |
R6344 |
T9197 |
T9205 |
arg1Of |
examined,in |
R6345 |
T9197 |
T9208 |
arg1Of |
examined,by |
R6346 |
T9200 |
T9197 |
arg2Of |
pattern,examined |
R6347 |
T9200 |
T9198 |
arg1Of |
pattern,the |
R6348 |
T9200 |
T9199 |
arg1Of |
pattern,spatial |
R6349 |
T9200 |
T9201 |
arg1Of |
pattern,of |
R6350 |
T9204 |
T9201 |
arg2Of |
transcripts,of |
R6351 |
T9204 |
T9202 |
arg1Of |
transcripts,ɛy |
R6352 |
T9204 |
T9203 |
arg1Of |
transcripts,globin |
R6353 |
T9207 |
T9205 |
arg2Of |
embryos,in |
R6354 |
T9207 |
T9206 |
arg1Of |
embryos,mouse |
R6355 |
T9210 |
T9209 |
arg1Of |
situ,in |
R6356 |
T9211 |
T9208 |
arg2Of |
hybridization,by |
R6357 |
T9211 |
T9210 |
arg1Of |
hybridization,situ |
R6358 |
T9211 |
T9212 |
arg1Of |
hybridization,( |
R6359 |
T9213 |
T9212 |
arg2Of |
Figure,( |
R6360 |
T9213 |
T9214 |
arg1Of |
Figure,5 |
R6361 |
T9215 |
T9212 |
arg3Of |
),( |
R6362 |
T9217 |
T9216 |
arg2Of |
expected,As |
R6363 |
T9220 |
T9219 |
arg1Of |
globin,ɛy |
R6364 |
T9220 |
T9221 |
arg1Of |
globin,is |
R6365 |
T9220 |
T9223 |
arg2Of |
globin,expressed |
R6366 |
T9223 |
T9216 |
arg1Of |
expressed,As |
R6367 |
T9223 |
T9218 |
arg1Of |
expressed,"," |
R6368 |
T9223 |
T9221 |
arg2Of |
expressed,is |
R6369 |
T9223 |
T9222 |
arg1Of |
expressed,not |
R6370 |
T9223 |
T9224 |
arg1Of |
expressed,in |
R6371 |
T9228 |
T9224 |
arg2Of |
liver,in |
R6372 |
T9228 |
T9225 |
arg1Of |
liver,the |
R6373 |
T9228 |
T9226 |
arg1Of |
liver,WT |
R6374 |
T9228 |
T9227 |
arg1Of |
liver,14.5-dpc |
R6375 |
T9228 |
T9229 |
arg1Of |
liver,"," |
R6376 |
T9231 |
T9229 |
arg2Of |
site,"," |
R6377 |
T9231 |
T9230 |
arg1Of |
site,the |
R6378 |
T9231 |
T9232 |
arg1Of |
site,of |
R6379 |
T9231 |
T9235 |
arg1Of |
site,in |
R6380 |
T9234 |
T9232 |
arg2Of |
erythropoiesis,of |
R6381 |
T9234 |
T9233 |
arg1Of |
erythropoiesis,definitive |
R6382 |
T9237 |
T9235 |
arg2Of |
fetus,in |
R6383 |
T9237 |
T9236 |
arg1Of |
fetus,the |
R6384 |
T9239 |
T9238 |
arg2Of |
contrast,In |
R6385 |
T9245 |
T9241 |
arg1Of |
expression,abundant |
R6386 |
T9245 |
T9242 |
arg1Of |
expression,ectopic |
R6387 |
T9245 |
T9243 |
arg1Of |
expression,ɛy |
R6388 |
T9245 |
T9244 |
arg1Of |
expression,mRNA |
R6389 |
T9245 |
T9246 |
arg1Of |
expression,is |
R6390 |
T9245 |
T9247 |
arg2Of |
expression,seen |
R6391 |
T9247 |
T9238 |
arg1Of |
seen,In |
R6392 |
T9247 |
T9240 |
arg1Of |
seen,"," |
R6393 |
T9247 |
T9246 |
arg2Of |
seen,is |
R6394 |
T9247 |
T9248 |
arg1Of |
seen,in |
R6395 |
T9250 |
T9248 |
arg2Of |
liver,in |
R6396 |
T9250 |
T9249 |
arg1Of |
liver,the |
R6397 |
T9250 |
T9251 |
arg1Of |
liver,of |
R6398 |
T9253 |
T9251 |
arg2Of |
mutants,of |
R6399 |
T9253 |
T9252 |
arg1Of |
mutants,14.5-dpc |
R64 |
T280 |
T278 |
arg3Of |
),( |
R6400 |
T9253 |
T9254 |
arg1Of |
mutants,( |
R6401 |
T9257 |
T9254 |
arg2Of |
A–D,( |
R6402 |
T9257 |
T9255 |
arg1Of |
A–D,Figure |
R6403 |
T9257 |
T9256 |
arg1Of |
A–D,5 |
R6404 |
T9258 |
T9254 |
arg3Of |
),( |
R6405 |
T9262 |
T9261 |
arg1Of |
expression,the |
R6406 |
T9262 |
T9263 |
arg1Of |
expression,of |
R6407 |
T9262 |
T9266 |
arg1Of |
expression,is |
R6408 |
T9262 |
T9268 |
arg1Of |
expression,abundant |
R6409 |
T9265 |
T9263 |
arg2Of |
globin,of |
R6410 |
T9265 |
T9264 |
arg1Of |
globin,βmaj/min |
R6411 |
T9266 |
T9259 |
arg1Of |
is,However |
R6412 |
T9266 |
T9260 |
arg1Of |
is,"," |
R6413 |
T9268 |
T9266 |
arg2Of |
abundant,is |
R6414 |
T9268 |
T9267 |
arg1Of |
abundant,equally |
R6415 |
T9268 |
T9269 |
arg1Of |
abundant,in |
R6416 |
T9271 |
T9272 |
arg1Of |
WT,and |
R6417 |
T9273 |
T9272 |
arg2Of |
p100H,and |
R6418 |
T9275 |
T9269 |
arg2Of |
mice,in |
R6419 |
T9275 |
T9270 |
arg1Of |
mice,both |
R6420 |
T9275 |
T9271 |
arg1Of |
mice,WT |
R6421 |
T9275 |
T9273 |
arg1Of |
mice,p100H |
R6422 |
T9275 |
T9274 |
arg1Of |
mice,mutant |
R6423 |
T9275 |
T9276 |
arg1Of |
mice,( |
R6424 |
T9279 |
T9280 |
arg1Of |
E,and |
R6425 |
T9280 |
T9276 |
arg2Of |
and,( |
R6426 |
T9280 |
T9277 |
arg1Of |
and,Figure |
R6427 |
T9280 |
T9278 |
arg1Of |
and,5 |
R6428 |
T9281 |
T9280 |
arg2Of |
F,and |
R6429 |
T9282 |
T9276 |
arg3Of |
),( |
R6430 |
T9284 |
T9283 |
arg1Of |
data,These |
R6431 |
T9284 |
T9285 |
arg1Of |
data,demonstrate |
R6432 |
T9285 |
T9309 |
arg1Of |
demonstrate,"," |
R6433 |
T9285 |
T9310 |
modOf |
demonstrate,suggesting |
R6434 |
T9290 |
T9287 |
arg1Of |
levels,the |
R6435 |
T9290 |
T9288 |
arg1Of |
levels,persistent |
R6436 |
T9290 |
T9289 |
arg1Of |
levels,high |
R6437 |
T9290 |
T9291 |
arg1Of |
levels,of |
R6438 |
T9290 |
T9293 |
arg1Of |
levels,are |
R6439 |
T9290 |
T9294 |
arg1Of |
levels,due |
R6440 |
T9292 |
T9291 |
arg2Of |
ɛy,of |
R6441 |
T9293 |
T9285 |
arg2Of |
are,demonstrate |
R6442 |
T9293 |
T9286 |
arg1Of |
are,that |
R6443 |
T9294 |
T9293 |
arg2Of |
due,are |
R6444 |
T9294 |
T9295 |
arg1Of |
due,to |
R6445 |
T9297 |
T9295 |
arg2Of |
expression,to |
R6446 |
T9297 |
T9296 |
arg1Of |
expression,ectopic |
R6447 |
T9297 |
T9298 |
arg1Of |
expression,in |
R6448 |
T9302 |
T9298 |
arg2Of |
cells,in |
R6449 |
T9302 |
T9299 |
arg1Of |
cells,the |
R6450 |
T9302 |
T9300 |
arg1Of |
cells,definitive |
R6451 |
T9302 |
T9301 |
arg1Of |
cells,erythroid |
R6452 |
T9302 |
T9303 |
arg1Of |
cells,that |
R6453 |
T9302 |
T9304 |
arg1Of |
cells,mature |
R6454 |
T9304 |
T9305 |
arg1Of |
mature,in |
R6455 |
T9308 |
T9305 |
arg2Of |
liver,in |
R6456 |
T9308 |
T9306 |
arg1Of |
liver,the |
R6457 |
T9308 |
T9307 |
arg1Of |
liver,fetal |
R6458 |
T9312 |
T9313 |
arg1Of |
there,is |
R6459 |
T9313 |
T9310 |
arg2Of |
is,suggesting |
R6460 |
T9313 |
T9311 |
arg1Of |
is,that |
R6461 |
T9316 |
T9313 |
arg2Of |
defect,is |
R6462 |
T9316 |
T9314 |
arg1Of |
defect,an |
R6463 |
T9316 |
T9315 |
arg1Of |
defect,intrinsic |
R6464 |
T9316 |
T9317 |
arg1Of |
defect,of |
R6465 |
T9316 |
T9322 |
arg1Of |
defect,in |
R6466 |
T9321 |
T9317 |
arg2Of |
mechanism,of |
R6467 |
T9321 |
T9318 |
arg1Of |
mechanism,the |
R6468 |
T9321 |
T9319 |
arg1Of |
mechanism,ɛy |
R6469 |
T9321 |
T9320 |
arg1Of |
mechanism,silencing |
R6470 |
T9324 |
T9322 |
arg2Of |
mice,in |
R6471 |
T9324 |
T9323 |
arg1Of |
mice,Sox6-null |
R65 |
T283 |
T271 |
arg1Of |
domain,defined |
R66 |
T283 |
T272 |
arg2Of |
domain,by |
R67 |
T283 |
T273 |
arg1Of |
domain,the |
R6781 |
T9864 |
T9862 |
arg1Of |
Pattern,The |
R6782 |
T9864 |
T9863 |
arg1Of |
Pattern,Expression |
R6783 |
T9864 |
T9865 |
arg1Of |
Pattern,of |
R6784 |
T9864 |
T9867 |
arg1Of |
Pattern,Suggests |
R6785 |
T9866 |
T9865 |
arg2Of |
Sox6,of |
R6786 |
T9867 |
T9870 |
arg1Of |
Suggests,in |
R6787 |
T9869 |
T9867 |
arg2Of |
Role,Suggests |
R6788 |
T9869 |
T9868 |
arg1Of |
Role,a |
R6789 |
T9872 |
T9870 |
arg2Of |
Erythropoiesis,in |
R6790 |
T9872 |
T9871 |
arg1Of |
Erythropoiesis,Definitive |
R6791 |
T9874 |
T9873 |
arg1Of |
observation,The |
R6792 |
T9874 |
T9891 |
arg1Of |
observation,suggests |
R6793 |
T9877 |
T9876 |
arg1Of |
mice,Sox6-deficient |
R6794 |
T9877 |
T9879 |
arg1Of |
mice,express |
R6795 |
T9879 |
T9874 |
arg2Of |
express,observation |
R6796 |
T9879 |
T9875 |
arg1Of |
express,that |
R6797 |
T9879 |
T9878 |
arg1Of |
express,ectopically |
R6798 |
T9879 |
T9882 |
arg1Of |
express,in |
R6799 |
T9881 |
T9879 |
arg2Of |
globin,express |
R68 |
T283 |
T274 |
arg2Of |
domain,conserved |
R6800 |
T9881 |
T9880 |
arg1Of |
globin,ɛy |
R6801 |
T9883 |
T9882 |
arg2Of |
liver,in |
R6802 |
T9883 |
T9884 |
arg1Of |
liver,"," |
R6803 |
T9883 |
T9885 |
arg1Of |
liver,where |
R6804 |
T9888 |
T9886 |
arg1Of |
cells,definitive |
R6805 |
T9888 |
T9887 |
arg1Of |
cells,erythroid |
R6806 |
T9888 |
T9889 |
arg1Of |
cells,mature |
R6807 |
T9889 |
T9885 |
arg2Of |
mature,where |
R6808 |
T9891 |
T9890 |
arg1Of |
suggests,"," |
R6809 |
T9893 |
T9894 |
arg1Of |
Sox6,is |
R6810 |
T9894 |
T9891 |
arg2Of |
is,suggests |
R6811 |
T9894 |
T9892 |
arg1Of |
is,that |
R6812 |
T9897 |
T9894 |
arg2Of |
regulator,is |
R6813 |
T9897 |
T9895 |
arg1Of |
regulator,an |
R6814 |
T9897 |
T9896 |
arg1Of |
regulator,important |
R6815 |
T9897 |
T9898 |
arg1Of |
regulator,in |
R6816 |
T9900 |
T9898 |
arg2Of |
erythropoiesis,in |
R6817 |
T9900 |
T9899 |
arg1Of |
erythropoiesis,definitive |
R6818 |
T9902 |
T9901 |
arg1Of |
determine,To |
R6819 |
T9904 |
T9905 |
arg1Of |
temporal,and |
R6820 |
T9906 |
T9905 |
arg2Of |
spatial,and |
R6821 |
T9908 |
T9902 |
arg2Of |
pattern,determine |
R6822 |
T9908 |
T9903 |
arg1Of |
pattern,the |
R6823 |
T9908 |
T9904 |
arg1Of |
pattern,temporal |
R6824 |
T9908 |
T9906 |
arg1Of |
pattern,spatial |
R6825 |
T9908 |
T9907 |
arg1Of |
pattern,expression |
R6826 |
T9908 |
T9909 |
arg1Of |
pattern,of |
R6827 |
T9910 |
T9909 |
arg2Of |
Sox6,of |
R6828 |
T9913 |
T9912 |
arg1Of |
blot,Northern |
R6829 |
T9913 |
T9914 |
arg1Of |
blot,and |
R6830 |
T9914 |
T9919 |
arg1Of |
and,were |
R6831 |
T9914 |
T9920 |
arg2Of |
and,employed |
R6832 |
T9916 |
T9915 |
arg1Of |
situ,in |
R6833 |
T9918 |
T9914 |
arg2Of |
assays,and |
R6834 |
T9918 |
T9916 |
arg1Of |
assays,situ |
R6835 |
T9918 |
T9917 |
arg1Of |
assays,hybridization |
R6836 |
T9920 |
T9901 |
modOf |
employed,To |
R6837 |
T9920 |
T9911 |
arg1Of |
employed,"," |
R6838 |
T9920 |
T9919 |
arg2Of |
employed,were |
R6839 |
T9922 |
T9921 |
arg2Of |
shown,As |
R6840 |
T9922 |
T9923 |
arg1Of |
shown,in |
R6841 |
T9925 |
T9923 |
arg2Of |
6A,in |
R6842 |
T9925 |
T9924 |
arg1Of |
6A,Figure |
R6843 |
T9927 |
T9928 |
arg1Of |
Sox6,is |
R6844 |
T9927 |
T9929 |
arg1Of |
Sox6,detectable |
R6845 |
T9928 |
T9921 |
arg1Of |
is,As |
R6846 |
T9928 |
T9926 |
arg1Of |
is,"," |
R6847 |
T9928 |
T9937 |
arg1Of |
is,"," |
R6848 |
T9928 |
T9938 |
arg1Of |
is,coincident |
R6849 |
T9929 |
T9928 |
arg2Of |
detectable,is |
R6850 |
T9929 |
T9930 |
arg1Of |
detectable,by |
R6851 |
T9932 |
T9930 |
arg2Of |
blot,by |
R6852 |
T9932 |
T9931 |
arg1Of |
blot,Northern |
R6853 |
T9932 |
T9933 |
arg1Of |
blot,beginning |
R6854 |
T9933 |
T9934 |
arg1Of |
beginning,at |
R6855 |
T9936 |
T9934 |
arg2Of |
dpc,at |
R6856 |
T9936 |
T9935 |
arg1Of |
dpc,10.5 |
R6857 |
T9938 |
T9939 |
arg1Of |
coincident,with |
R6858 |
T9942 |
T9939 |
arg2Of |
onset,with |
R6859 |
T9942 |
T9940 |
arg1Of |
onset,the |
R6860 |
T9942 |
T9941 |
arg1Of |
onset,temporal |
R6861 |
T9942 |
T9943 |
arg1Of |
onset,of |
R6862 |
T9942 |
T9946 |
arg1Of |
onset,in |
R6863 |
T9945 |
T9943 |
arg2Of |
erythropoiesis,of |
R6864 |
T9945 |
T9944 |
arg1Of |
erythropoiesis,definitive |
R6865 |
T9948 |
T9946 |
arg2Of |
liver,in |
R6866 |
T9948 |
T9947 |
arg1Of |
liver,the |
R6867 |
T9952 |
T9951 |
arg1Of |
situ,in |
R6868 |
T9953 |
T9952 |
arg1Of |
hybridization,situ |
R6869 |
T9953 |
T9954 |
arg1Of |
hybridization,shows |
R6870 |
T9954 |
T9949 |
arg1Of |
shows,Furthermore |
R6871 |
T9954 |
T9950 |
arg1Of |
shows,"," |
R6872 |
T9956 |
T9957 |
arg1Of |
Sox6,is |
R6873 |
T9956 |
T9959 |
arg2Of |
Sox6,transcribed |
R6874 |
T9959 |
T9954 |
arg2Of |
transcribed,shows |
R6875 |
T9959 |
T9955 |
arg1Of |
transcribed,that |
R6876 |
T9959 |
T9957 |
arg2Of |
transcribed,is |
R6877 |
T9959 |
T9958 |
arg1Of |
transcribed,highly |
R6878 |
T9959 |
T9960 |
arg1Of |
transcribed,in |
R6879 |
T9959 |
T9966 |
arg1Of |
transcribed,in |
R6880 |
T9960 |
T9964 |
arg1Of |
in,but |
R6881 |
T9962 |
T9960 |
arg2Of |
liver,in |
R6882 |
T9962 |
T9961 |
arg1Of |
liver,12.5-dpc |
R6883 |
T9964 |
T9963 |
arg1Of |
but,"," |
R6884 |
T9966 |
T9964 |
arg2Of |
in,but |
R6885 |
T9966 |
T9965 |
arg1Of |
in,not |
R6886 |
T9970 |
T9966 |
arg2Of |
islands,in |
R6887 |
T9970 |
T9967 |
arg1Of |
islands,yolk |
R6888 |
T9970 |
T9968 |
arg1Of |
islands,sac |
R6889 |
T9970 |
T9969 |
arg1Of |
islands,blood |
R6890 |
T9970 |
T9971 |
arg1Of |
islands,at |
R6891 |
T9973 |
T9971 |
arg2Of |
dpc,at |
R6892 |
T9973 |
T9972 |
arg1Of |
dpc,7.5 |
R6893 |
T9973 |
T9974 |
arg1Of |
dpc,( |
R6894 |
T9976 |
T9974 |
arg2Of |
6B,( |
R6895 |
T9976 |
T9975 |
arg1Of |
6B,Figure |
R6896 |
T9977 |
T9974 |
arg3Of |
),( |
R6897 |
T9981 |
T9980 |
arg1Of |
expression,Sox6 |
R6898 |
T9981 |
T9982 |
arg1Of |
expression,is |
R6899 |
T9981 |
T9986 |
arg1Of |
expression,coincident |
R69 |
T283 |
T275 |
arg1Of |
domain,high |
R6900 |
T9982 |
T9978 |
arg1Of |
is,Therefore |
R6901 |
T9982 |
T9979 |
arg1Of |
is,"," |
R6902 |
T9983 |
T9984 |
arg1Of |
temporally,and |
R6903 |
T9985 |
T9984 |
arg2Of |
spatially,and |
R6904 |
T9986 |
T9982 |
arg2Of |
coincident,is |
R6905 |
T9986 |
T9983 |
arg1Of |
coincident,temporally |
R6906 |
T9986 |
T9985 |
arg1Of |
coincident,spatially |
R6907 |
T9986 |
T9987 |
arg1Of |
coincident,with |
R6908 |
T9988 |
T9990 |
arg1Of |
definitive,but |
R6909 |
T9990 |
T9989 |
arg1Of |
but,"," |
R6910 |
T9992 |
T9990 |
arg2Of |
primitive,but |
R6911 |
T9992 |
T9991 |
arg1Of |
primitive,not |
R6912 |
T9994 |
T9987 |
arg2Of |
erythropoiesis,with |
R6913 |
T9994 |
T9988 |
arg1Of |
erythropoiesis,definitive |
R6914 |
T9994 |
T9992 |
arg1Of |
erythropoiesis,primitive |
R6915 |
T9994 |
T9993 |
arg1Of |
erythropoiesis,"," |
R6916 |
T9996 |
T9995 |
arg1Of |
data,These |
R6917 |
T9996 |
T9998 |
arg2Of |
data,taken |
R6918 |
T9996 |
T10023 |
arg1Of |
data,demonstrate |
R6919 |
T9998 |
T9997 |
arg1Of |
taken,"," |
R6920 |
T9998 |
T9999 |
arg1Of |
taken,together |
R6921 |
T9998 |
T10000 |
arg1Of |
taken,with |
R6922 |
T10002 |
T10000 |
arg2Of |
observation,with |
R6923 |
T10002 |
T10001 |
arg1Of |
observation,the |
R6924 |
T10005 |
T10004 |
arg1Of |
globin,ɛy |
R6925 |
T10005 |
T10006 |
arg1Of |
globin,is |
R6926 |
T10005 |
T10008 |
arg2Of |
globin,expressed |
R6927 |
T10008 |
T10002 |
arg2Of |
expressed,observation |
R6928 |
T10008 |
T10003 |
arg1Of |
expressed,that |
R6929 |
T10008 |
T10006 |
arg2Of |
expressed,is |
R6930 |
T10008 |
T10007 |
arg1Of |
expressed,highly |
R6931 |
T10008 |
T10009 |
arg1Of |
expressed,in |
R6932 |
T10012 |
T10009 |
arg2Of |
cells,in |
R6933 |
T10012 |
T10010 |
arg1Of |
cells,the |
R6934 |
T10012 |
T10011 |
arg1Of |
cells,liver |
R6935 |
T10012 |
T10013 |
arg1Of |
cells,of |
R6936 |
T10017 |
T10013 |
arg2Of |
mice,of |
R6937 |
T10017 |
T10014 |
arg1Of |
mice,14.5-dpc |
R6938 |
T10017 |
T10015 |
arg1Of |
mice,p100H |
R6939 |
T10017 |
T10016 |
arg1Of |
mice,mutant |
R6940 |
T10017 |
T10018 |
arg1Of |
mice,( |
R6941 |
T10019 |
T10018 |
arg2Of |
Figure,( |
R6942 |
T10019 |
T10020 |
arg1Of |
Figure,5 |
R6943 |
T10021 |
T10018 |
arg3Of |
),( |
R6944 |
T10023 |
T10022 |
arg1Of |
demonstrate,"," |
R6945 |
T10023 |
T10027 |
arg1Of |
demonstrate,in |
R6946 |
T10026 |
T10023 |
arg2Of |
functions,demonstrate |
R6947 |
T10026 |
T10024 |
arg1Of |
functions,that |
R6948 |
T10026 |
T10025 |
arg1Of |
functions,Sox6 |
R6949 |
T10029 |
T10027 |
arg2Of |
erythropoiesis,in |
R6950 |
T10029 |
T10028 |
arg1Of |
erythropoiesis,definitive |
R70 |
T283 |
T276 |
arg1Of |
domain,mobility |
R71 |
T283 |
T277 |
arg1Of |
domain,group |
R7164 |
T10376 |
T10371 |
arg1Of |
Numbers,Mutant |
R7165 |
T10376 |
T10372 |
arg1Of |
Numbers,p100H |
R7166 |
T10376 |
T10373 |
arg1Of |
Numbers,Mice |
R7167 |
T10376 |
T10374 |
arg1Of |
Numbers,Have |
R7168 |
T10376 |
T10375 |
arg1Of |
Numbers,Higher |
R7169 |
T10376 |
T10377 |
arg1Of |
Numbers,of |
R7170 |
T10380 |
T10377 |
arg2Of |
Cells,of |
R7171 |
T10380 |
T10378 |
arg1Of |
Cells,Nucleated |
R7172 |
T10380 |
T10379 |
arg1Of |
Cells,Red |
R7173 |
T10385 |
T10381 |
arg2Of |
effects,Among |
R7174 |
T10385 |
T10382 |
arg1Of |
effects,the |
R7175 |
T10385 |
T10383 |
arg1Of |
effects,other |
R7176 |
T10385 |
T10384 |
arg1Of |
effects,Sox6 |
R7177 |
T10385 |
T10386 |
arg1Of |
effects,in |
R7178 |
T10387 |
T10386 |
arg2Of |
erythropoiesis,in |
R7179 |
T10389 |
T10390 |
arg1Of |
we,have |
R7180 |
T10389 |
T10391 |
arg1Of |
we,noticed |
R7181 |
T10391 |
T10381 |
arg1Of |
noticed,Among |
R7182 |
T10391 |
T10388 |
arg1Of |
noticed,"," |
R7183 |
T10391 |
T10390 |
arg2Of |
noticed,have |
R7184 |
T10393 |
T10394 |
arg1Of |
there,are |
R7185 |
T10394 |
T10391 |
arg2Of |
are,noticed |
R7186 |
T10394 |
T10392 |
arg1Of |
are,that |
R7187 |
T10394 |
T10405 |
arg1Of |
are,than |
R7188 |
T10394 |
T10409 |
arg1Of |
are,at |
R7189 |
T10396 |
T10395 |
arg1Of |
nucleated,more |
R7190 |
T10399 |
T10394 |
arg2Of |
cells,are |
R7191 |
T10399 |
T10396 |
arg1Of |
cells,nucleated |
R7192 |
T10399 |
T10397 |
arg1Of |
cells,red |
R7193 |
T10399 |
T10398 |
arg1Of |
cells,blood |
R7194 |
T10399 |
T10400 |
arg1Of |
cells,circulating |
R7195 |
T10400 |
T10401 |
arg1Of |
circulating,in |
R7196 |
T10404 |
T10401 |
arg2Of |
mice,in |
R7197 |
T10404 |
T10402 |
arg1Of |
mice,p100H |
R7198 |
T10404 |
T10403 |
arg1Of |
mice,mutant |
R7199 |
T10406 |
T10405 |
arg2Of |
in,than |
R72 |
T283 |
T278 |
arg1Of |
domain,( |
R7200 |
T10408 |
T10406 |
arg2Of |
mice,in |
R7201 |
T10408 |
T10407 |
arg1Of |
mice,WT |
R7202 |
T10411 |
T10410 |
arg1Of |
dpc,14.5 |
R7203 |
T10411 |
T10412 |
arg1Of |
dpc,and |
R7204 |
T10412 |
T10409 |
arg2Of |
and,at |
R7205 |
T10414 |
T10412 |
arg2Of |
dpc,and |
R7206 |
T10414 |
T10413 |
arg1Of |
dpc,18.5 |
R7207 |
T10414 |
T10415 |
arg1Of |
dpc,( |
R7208 |
T10417 |
T10415 |
arg2Of |
7A,( |
R7209 |
T10417 |
T10416 |
arg1Of |
7A,Figure |
R7210 |
T10418 |
T10415 |
arg3Of |
),( |
R7211 |
T10423 |
T10421 |
arg2Of |
day,at |
R7212 |
T10423 |
T10422 |
arg1Of |
day,postnatal |
R7213 |
T10423 |
T10424 |
arg1Of |
day,10.5 |
R7214 |
T10426 |
T10427 |
arg1Of |
we,do |
R7215 |
T10426 |
T10429 |
arg1Of |
we,see |
R7216 |
T10429 |
T10419 |
arg1Of |
see,However |
R7217 |
T10429 |
T10420 |
arg1Of |
see,"," |
R7218 |
T10429 |
T10421 |
arg1Of |
see,at |
R7219 |
T10429 |
T10425 |
arg1Of |
see,"," |
R7220 |
T10429 |
T10427 |
arg2Of |
see,do |
R7221 |
T10429 |
T10428 |
arg1Of |
see,not |
R7222 |
T10429 |
T10440 |
arg1Of |
see,"," |
R7223 |
T10429 |
T10441 |
modOf |
see,suggesting |
R7224 |
T10430 |
T10429 |
arg2Of |
circulating,see |
R7225 |
T10432 |
T10431 |
arg1Of |
red,nucleated |
R7226 |
T10433 |
T10430 |
arg2Of |
cells,circulating |
R7227 |
T10433 |
T10432 |
arg1Of |
cells,red |
R7228 |
T10433 |
T10434 |
arg1Of |
cells,in |
R7229 |
T10436 |
T10437 |
arg1Of |
WT,or |
R7230 |
T10437 |
T10434 |
arg2Of |
or,in |
R7231 |
T10437 |
T10435 |
arg1Of |
or,either |
R7232 |
T10439 |
T10437 |
arg2Of |
mice,or |
R7233 |
T10439 |
T10438 |
arg1Of |
mice,mutant |
R7234 |
T10443 |
T10444 |
arg1Of |
this,may |
R7235 |
T10443 |
T10445 |
arg1Of |
this,be |
R7236 |
T10445 |
T10441 |
arg2Of |
be,suggesting |
R7237 |
T10445 |
T10442 |
arg1Of |
be,that |
R7238 |
T10445 |
T10444 |
arg2Of |
be,may |
R7239 |
T10448 |
T10445 |
arg2Of |
effect,be |
R7240 |
T10448 |
T10446 |
arg1Of |
effect,a |
R7241 |
T10448 |
T10447 |
arg1Of |
effect,transient |
R7242 |
T10450 |
T10449 |
arg2Of |
addition,In |
R7243 |
T10454 |
T10452 |
arg1Of |
liver,the |
R7244 |
T10454 |
T10453 |
arg1Of |
liver,mutant |
R7245 |
T10454 |
T10455 |
arg1Of |
liver,shows |
R7246 |
T10455 |
T10449 |
arg1Of |
shows,In |
R7247 |
T10455 |
T10451 |
arg1Of |
shows,"," |
R7248 |
T10458 |
T10455 |
arg2Of |
increase,shows |
R7249 |
T10458 |
T10456 |
arg1Of |
increase,a |
R7250 |
T10458 |
T10457 |
arg1Of |
increase,significant |
R7251 |
T10458 |
T10459 |
arg1Of |
increase,in |
R7252 |
T10462 |
T10459 |
arg2Of |
cells,in |
R7253 |
T10462 |
T10460 |
arg1Of |
cells,hematopoietic |
R7254 |
T10462 |
T10461 |
arg1Of |
cells,precursor |
R7255 |
T10462 |
T10463 |
arg1Of |
cells,including |
R7256 |
T10465 |
T10463 |
arg2Of |
erythrocytes,including |
R7257 |
T10465 |
T10464 |
arg1Of |
erythrocytes,nucleated |
R7258 |
T10465 |
T10466 |
arg1Of |
erythrocytes,at |
R7259 |
T10468 |
T10466 |
arg2Of |
dpc,at |
R7260 |
T10468 |
T10467 |
arg1Of |
dpc,18.5 |
R7261 |
T10468 |
T10469 |
arg1Of |
dpc,( |
R7262 |
T10471 |
T10469 |
arg2Of |
7B,( |
R7263 |
T10471 |
T10470 |
arg1Of |
7B,Figure |
R7264 |
T10472 |
T10469 |
arg3Of |
),( |
R7265 |
T10474 |
T10473 |
arg1Of |
alteration,This |
R7266 |
T10474 |
T10475 |
arg1Of |
alteration,is |
R7267 |
T10474 |
T10476 |
arg2Of |
alteration,noted |
R7268 |
T10476 |
T10475 |
arg2Of |
noted,is |
R7269 |
T10476 |
T10478 |
arg1Of |
noted,early |
R7270 |
T10478 |
T10477 |
arg1Of |
early,as |
R7271 |
T10478 |
T10479 |
arg1Of |
early,as |
R7272 |
T10481 |
T10479 |
arg2Of |
dpc,as |
R7273 |
T10481 |
T10480 |
arg1Of |
dpc,14.5 |
R7274 |
T10483 |
T10482 |
arg1Of |
observations,These |
R7275 |
T10483 |
T10484 |
arg1Of |
observations,suggest |
R7276 |
T10487 |
T10486 |
arg2Of |
silencing,besides |
R7277 |
T10491 |
T10487 |
arg2Of |
gene,silencing |
R7278 |
T10491 |
T10488 |
arg1Of |
gene,the |
R7279 |
T10491 |
T10489 |
arg1Of |
gene,ɛy |
R7280 |
T10491 |
T10490 |
arg1Of |
gene,globin |
R7281 |
T10493 |
T10487 |
arg1Of |
Sox6,silencing |
R7282 |
T10493 |
T10494 |
arg1Of |
Sox6,may |
R7283 |
T10493 |
T10495 |
arg1Of |
Sox6,affect |
R7284 |
T10495 |
T10484 |
arg2Of |
affect,suggest |
R7285 |
T10495 |
T10485 |
arg1Of |
affect,that |
R7286 |
T10495 |
T10486 |
arg1Of |
affect,besides |
R7287 |
T10495 |
T10492 |
arg1Of |
affect,"," |
R7288 |
T10495 |
T10494 |
arg2Of |
affect,may |
R7289 |
T10498 |
T10495 |
arg2Of |
maturation,affect |
R7290 |
T10498 |
T10496 |
arg1Of |
maturation,red |
R7291 |
T10498 |
T10497 |
arg1Of |
maturation,cell |
R73 |
T283 |
T281 |
arg1Of |
domain,DNA |
R74 |
T283 |
T282 |
arg1Of |
domain,binding |
R75 |
T283 |
T284 |
arg1Of |
domain,"," |
R76 |
T283 |
T286 |
arg2Of |
domain,described |
R7691 |
T11820 |
T11818 |
arg2Of |
report,In |
R7692 |
T11820 |
T11819 |
arg1Of |
report,this |
R7693 |
T11822 |
T11823 |
arg1Of |
we,show |
R7694 |
T11823 |
T11818 |
arg1Of |
show,In |
R7695 |
T11823 |
T11821 |
arg1Of |
show,"," |
R7696 |
T11825 |
T11826 |
arg1Of |
Sox6,is |
R7697 |
T11826 |
T11823 |
arg2Of |
is,show |
R7698 |
T11826 |
T11824 |
arg1Of |
is,that |
R7699 |
T11829 |
T11826 |
arg2Of |
factor,is |
R77 |
T286 |
T285 |
arg1Of |
described,first |
R7700 |
T11829 |
T11827 |
arg1Of |
factor,a |
R7701 |
T11829 |
T11828 |
arg1Of |
factor,novel |
R7702 |
T11829 |
T11830 |
arg1Of |
factor,in |
R7703 |
T11834 |
T11830 |
arg2Of |
mechanism,in |
R7704 |
T11834 |
T11831 |
arg1Of |
mechanism,the |
R7705 |
T11834 |
T11832 |
arg2Of |
mechanism,complicated |
R7706 |
T11834 |
T11833 |
arg1Of |
mechanism,regulation |
R7707 |
T11834 |
T11835 |
arg1Of |
mechanism,of |
R7708 |
T11837 |
T11835 |
arg2Of |
genes,of |
R7709 |
T11837 |
T11836 |
arg1Of |
genes,globin |
R7710 |
T11842 |
T11838 |
arg2Of |
mouse,In |
R7711 |
T11842 |
T11839 |
arg1Of |
mouse,the |
R7712 |
T11842 |
T11840 |
arg1Of |
mouse,Sox6 |
R7713 |
T11842 |
T11841 |
arg1Of |
mouse,null |
R7714 |
T11844 |
T11845 |
arg1Of |
there,is |
R7715 |
T11845 |
T11838 |
arg1Of |
is,In |
R7716 |
T11845 |
T11843 |
arg1Of |
is,"," |
R7717 |
T11848 |
T11845 |
arg2Of |
effect,is |
R7718 |
T11848 |
T11846 |
arg1Of |
effect,a |
R7719 |
T11848 |
T11847 |
arg1Of |
effect,transient |
R7720 |
T11848 |
T11849 |
arg1Of |
effect,on |
R7721 |
T11853 |
T11850 |
arg1Of |
genes,the |
R7722 |
T11853 |
T11851 |
arg1Of |
genes,embryonic |
R7723 |
T11853 |
T11852 |
arg1Of |
genes,globin |
R7724 |
T11853 |
T11854 |
arg1Of |
genes,"," |
R7725 |
T11853 |
T11859 |
arg1Of |
genes,and |
R7726 |
T11855 |
T11856 |
arg1Of |
ζ,and |
R7727 |
T11856 |
T11854 |
arg2Of |
and,"," |
R7728 |
T11857 |
T11856 |
arg2Of |
βH1,and |
R7729 |
T11859 |
T11849 |
arg2Of |
and,on |
R7730 |
T11859 |
T11858 |
arg1Of |
and,"," |
R7731 |
T11862 |
T11859 |
arg2Of |
upregulation,and |
R7732 |
T11862 |
T11860 |
arg1Of |
upregulation,a |
R7733 |
T11862 |
T11861 |
arg1Of |
upregulation,persistent |
R7734 |
T11862 |
T11863 |
arg1Of |
upregulation,of |
R7735 |
T11867 |
T11863 |
arg2Of |
gene,of |
R7736 |
T11867 |
T11864 |
arg1Of |
gene,the |
R7737 |
T11867 |
T11865 |
arg1Of |
gene,ɛy |
R7738 |
T11867 |
T11866 |
arg1Of |
gene,globin |
R7739 |
T11868 |
T11870 |
arg1Of |
Sox6,regulates |
R7740 |
T11868 |
T11872 |
arg1Of |
Sox6,binds |
R7741 |
T11868 |
T11881 |
arg1Of |
Sox6,represses |
R7742 |
T11870 |
T11871 |
arg1Of |
regulates,and |
R7743 |
T11871 |
T11880 |
arg1Of |
and,and |
R7744 |
T11872 |
T11871 |
arg2Of |
binds,and |
R7745 |
T11872 |
T11873 |
arg1Of |
binds,to |
R7746 |
T11876 |
T11873 |
arg2Of |
promoter,to |
R7747 |
T11876 |
T11874 |
arg1Of |
promoter,the |
R7748 |
T11876 |
T11875 |
arg1Of |
promoter,proximal |
R7749 |
T11876 |
T11877 |
arg1Of |
promoter,of |
R7750 |
T11879 |
T11877 |
arg2Of |
gene,of |
R7751 |
T11879 |
T11878 |
arg1Of |
gene,ɛy |
R7752 |
T11880 |
T11869 |
arg1Of |
and,directly |
R7753 |
T11881 |
T11880 |
arg2Of |
represses,and |
R7754 |
T11884 |
T11881 |
arg2Of |
gene,represses |
R7755 |
T11884 |
T11882 |
arg1Of |
gene,the |
R7756 |
T11884 |
T11883 |
arg1Of |
gene,ɛy-globin |
R7757 |
T11884 |
T11885 |
arg1Of |
gene,in |
R7758 |
T11887 |
T11885 |
arg2Of |
erythropoiesis,in |
R7759 |
T11887 |
T11886 |
arg1Of |
erythropoiesis,definitive |
R7760 |
T11888 |
T11889 |
arg1Of |
Sox6,belongs |
R7761 |
T11889 |
T11890 |
arg1Of |
belongs,to |
R7762 |
T11892 |
T11890 |
arg2Of |
D,to |
R7763 |
T11892 |
T11891 |
arg1Of |
D,group |
R7764 |
T11892 |
T11893 |
arg1Of |
D,of |
R7765 |
T11896 |
T11893 |
arg2Of |
family,of |
R7766 |
T11896 |
T11894 |
arg1Of |
family,the |
R7767 |
T11896 |
T11895 |
arg1Of |
family,Sox |
R7768 |
T11896 |
T11897 |
arg1Of |
family,of |
R7769 |
T11896 |
T11899 |
arg1Of |
family,that |
R7770 |
T11896 |
T11900 |
arg1Of |
family,includes |
R7771 |
T11898 |
T11897 |
arg2Of |
proteins,of |
R7772 |
T11901 |
T11902 |
arg1Of |
Sox5,"," |
R7773 |
T11902 |
T11904 |
arg1Of |
",","," |
R7774 |
T11903 |
T11902 |
arg2Of |
12,"," |
R7775 |
T11904 |
T11907 |
arg1Of |
",",and |
R7776 |
T11905 |
T11904 |
arg2Of |
13,"," |
R7777 |
T11907 |
T11900 |
arg2Of |
and,includes |
R7778 |
T11907 |
T11906 |
arg1Of |
and,"," |
R7779 |
T11908 |
T11907 |
arg2Of |
23,and |
R7780 |
T11908 |
T11909 |
arg1Of |
23,[ |
R7781 |
T11910 |
T11909 |
arg2Of |
34,[ |
R7782 |
T11911 |
T11909 |
arg3Of |
],[ |
R7783 |
T11914 |
T11912 |
arg1Of |
Sox,Group |
R7784 |
T11914 |
T11913 |
arg1Of |
Sox,D |
R7785 |
T11915 |
T11914 |
arg1Of |
proteins,Sox |
R7786 |
T11915 |
T11916 |
arg1Of |
proteins,contain |
R7787 |
T11919 |
T11916 |
arg2Of |
domain,contain |
R7788 |
T11919 |
T11917 |
arg1Of |
domain,a |
R7789 |
T11919 |
T11918 |
arg1Of |
domain,coiled–coiled |
R7790 |
T11919 |
T11920 |
arg1Of |
domain,that |
R7791 |
T11919 |
T11921 |
arg1Of |
domain,mediates |
R7792 |
T11921 |
T11925 |
arg1Of |
mediates,[ |
R7793 |
T11922 |
T11923 |
arg1Of |
homo-,and |
R7794 |
T11923 |
T11921 |
arg2Of |
and,mediates |
R7795 |
T11924 |
T11923 |
arg2Of |
heterodimerization,and |
R7796 |
T11926 |
T11925 |
arg2Of |
"6,35",[ |
R7797 |
T11927 |
T11925 |
arg3Of |
],[ |
R7798 |
T11930 |
T11931 |
arg1Of |
dimerization,of |
R7799 |
T11930 |
T11935 |
arg1Of |
dimerization,has |
R78 |
T286 |
T287 |
arg1Of |
described,in |
R7800 |
T11930 |
T11936 |
arg1Of |
dimerization,been |
R7801 |
T11930 |
T11937 |
arg2Of |
dimerization,shown |
R7802 |
T11930 |
T11940 |
arg1Of |
dimerization,increase |
R7803 |
T11932 |
T11933 |
arg1Of |
Sox5,and |
R7804 |
T11933 |
T11931 |
arg2Of |
and,of |
R7805 |
T11934 |
T11933 |
arg2Of |
Sox6,and |
R7806 |
T11937 |
T11928 |
arg1Of |
shown,Functionally |
R7807 |
T11937 |
T11929 |
arg1Of |
shown,"," |
R7808 |
T11937 |
T11935 |
arg2Of |
shown,has |
R7809 |
T11937 |
T11936 |
arg2Of |
shown,been |
R7810 |
T11940 |
T11937 |
arg3Of |
increase,shown |
R7811 |
T11940 |
T11938 |
arg1Of |
increase,to |
R7812 |
T11940 |
T11939 |
arg1Of |
increase,greatly |
R7813 |
T11943 |
T11940 |
arg2Of |
efficiency,increase |
R7814 |
T11943 |
T11941 |
arg1Of |
efficiency,the |
R7815 |
T11943 |
T11942 |
arg1Of |
efficiency,binding |
R7816 |
T11943 |
T11944 |
arg1Of |
efficiency,of |
R7817 |
T11943 |
T11949 |
arg1Of |
efficiency,to |
R7818 |
T11943 |
T11951 |
arg1Of |
efficiency,that |
R7819 |
T11943 |
T11952 |
arg1Of |
efficiency,contains |
R7820 |
T11948 |
T11944 |
arg2Of |
proteins,of |
R7821 |
T11948 |
T11945 |
arg1Of |
proteins,the |
R7822 |
T11948 |
T11946 |
arg1Of |
proteins,two |
R7823 |
T11948 |
T11947 |
arg1Of |
proteins,Sox |
R7824 |
T11950 |
T11949 |
arg2Of |
DNA,to |
R7825 |
T11955 |
T11952 |
arg2Of |
sites,contains |
R7826 |
T11955 |
T11953 |
arg1Of |
sites,adjacent |
R7827 |
T11955 |
T11954 |
arg1Of |
sites,Sox |
R7828 |
T11955 |
T11956 |
arg1Of |
sites,[ |
R7829 |
T11957 |
T11956 |
arg2Of |
6,[ |
R7830 |
T11958 |
T11956 |
arg3Of |
],[ |
R7831 |
T11960 |
T11959 |
arg2Of |
addition,In |
R7832 |
T11962 |
T11963 |
arg1Of |
Sox6,binds |
R7833 |
T11963 |
T11959 |
arg1Of |
binds,In |
R7834 |
T11963 |
T11961 |
arg1Of |
binds,"," |
R7835 |
T11963 |
T11965 |
arg1Of |
binds,strongly |
R7836 |
T11963 |
T11977 |
arg1Of |
binds,[ |
R7837 |
T11965 |
T11964 |
arg1Of |
strongly,more |
R7838 |
T11965 |
T11966 |
arg1Of |
strongly,to |
R7839 |
T11970 |
T11966 |
arg2Of |
motif,to |
R7840 |
T11970 |
T11967 |
arg1Of |
motif,an |
R7841 |
T11970 |
T11968 |
arg1Of |
motif,HMG-box |
R7842 |
T11970 |
T11969 |
arg1Of |
motif,dimer |
R7843 |
T11970 |
T11971 |
arg1Of |
motif,than |
R7844 |
T11972 |
T11971 |
arg2Of |
to,than |
R7845 |
T11976 |
T11972 |
arg2Of |
motif,to |
R7846 |
T11976 |
T11973 |
arg1Of |
motif,a |
R7847 |
T11976 |
T11974 |
arg1Of |
motif,single |
R7848 |
T11976 |
T11975 |
arg1Of |
motif,HMG-box |
R7849 |
T11978 |
T11977 |
arg2Of |
5,[ |
R7850 |
T11979 |
T11977 |
arg3Of |
],[ |
R7851 |
T11982 |
T11983 |
arg1Of |
it,appears |
R7852 |
T11983 |
T11980 |
arg1Of |
appears,Therefore |
R7853 |
T11983 |
T11981 |
arg1Of |
appears,"," |
R7854 |
T11986 |
T11985 |
arg1Of |
genes,target |
R7855 |
T11986 |
T11987 |
arg1Of |
genes,for |
R7856 |
T11986 |
T11998 |
arg1Of |
genes,harbor |
R7857 |
T11991 |
T11987 |
arg2Of |
proteins,for |
R7858 |
T11991 |
T11988 |
arg1Of |
proteins,group |
R7859 |
T11991 |
T11989 |
arg1Of |
proteins,D |
R7860 |
T11991 |
T11990 |
arg1Of |
proteins,Sox |
R7861 |
T11991 |
T11992 |
arg1Of |
proteins,"," |
R7862 |
T11991 |
T11994 |
arg1Of |
proteins,as |
R7863 |
T11994 |
T11993 |
arg1Of |
as,such |
R7864 |
T11995 |
T11994 |
arg2Of |
Sox6,as |
R7865 |
T11998 |
T11983 |
arg2Of |
harbor,appears |
R7866 |
T11998 |
T11984 |
arg1Of |
harbor,that |
R7867 |
T11998 |
T11996 |
arg1Of |
harbor,"," |
R7868 |
T11998 |
T11997 |
arg1Of |
harbor,probably |
R7869 |
T11999 |
T11998 |
arg2Of |
pairs,harbor |
R7870 |
T11999 |
T12000 |
arg1Of |
pairs,of |
R7871 |
T12003 |
T12000 |
arg2Of |
sites,of |
R7872 |
T12003 |
T12001 |
arg1Of |
sites,HMG |
R7873 |
T12003 |
T12002 |
arg1Of |
sites,binding |
R7874 |
T12003 |
T12004 |
arg1Of |
sites,with |
R7875 |
T12006 |
T12004 |
arg2Of |
configuration,with |
R7876 |
T12006 |
T12005 |
arg1Of |
configuration,a |
R7877 |
T12006 |
T12007 |
arg1Of |
configuration,compatible |
R7878 |
T12007 |
T12008 |
arg1Of |
compatible,with |
R7879 |
T12009 |
T12008 |
arg2Of |
binding,with |
R7880 |
T12009 |
T12010 |
arg1Of |
binding,of |
R7881 |
T12013 |
T12010 |
arg2Of |
dimers,of |
R7882 |
T12013 |
T12011 |
arg1Of |
dimers,D-Sox |
R7883 |
T12013 |
T12012 |
arg1Of |
dimers,protein |
R7884 |
T12019 |
T12016 |
arg2Of |
study,in |
R7885 |
T12019 |
T12017 |
arg1Of |
study,the |
R7886 |
T12019 |
T12018 |
arg1Of |
study,present |
R7887 |
T12025 |
T12021 |
arg1Of |
sequence,the |
R7888 |
T12025 |
T12022 |
arg2Of |
sequence,defined |
R7889 |
T12025 |
T12023 |
arg1Of |
sequence,Sox6 |
R7890 |
T12025 |
T12024 |
arg1Of |
sequence,target |
R7891 |
T12025 |
T12026 |
arg1Of |
sequence,of |
R7892 |
T12025 |
T12030 |
arg1Of |
sequence,contains |
R7893 |
T12029 |
T12026 |
arg2Of |
promoter,of |
R7894 |
T12029 |
T12027 |
arg1Of |
promoter,the |
R7895 |
T12029 |
T12028 |
arg1Of |
promoter,ɛy |
R7896 |
T12030 |
T12014 |
arg1Of |
contains,Indeed |
R7897 |
T12030 |
T12015 |
arg1Of |
contains,"," |
R7898 |
T12030 |
T12016 |
arg1Of |
contains,in |
R7899 |
T12030 |
T12020 |
arg1Of |
contains,"," |
R79 |
T289 |
T287 |
arg2Of |
testis,in |
R7900 |
T12034 |
T12030 |
arg2Of |
sites,contains |
R7901 |
T12034 |
T12031 |
arg1Of |
sites,two |
R7902 |
T12034 |
T12032 |
arg1Of |
sites,Sox/Sox6 |
R7903 |
T12034 |
T12033 |
arg1Of |
sites,consensus |
R7904 |
T12034 |
T12035 |
arg1Of |
sites,( |
R7905 |
T12037 |
T12035 |
arg2Of |
3A,( |
R7906 |
T12037 |
T12036 |
arg1Of |
3A,Figure |
R7907 |
T12038 |
T12035 |
arg3Of |
),( |
R7908 |
T12042 |
T12041 |
arg1Of |
sites,both |
R7909 |
T12042 |
T12043 |
arg1Of |
sites,are |
R7910 |
T12042 |
T12044 |
arg1Of |
sites,essential |
R7911 |
T12043 |
T12039 |
arg1Of |
are,Functionally |
R7912 |
T12043 |
T12040 |
arg1Of |
are,"," |
R7913 |
T12044 |
T12043 |
arg2Of |
essential,are |
R7914 |
T12044 |
T12045 |
arg1Of |
essential,for |
R7915 |
T12047 |
T12045 |
arg2Of |
binding,for |
R7916 |
T12047 |
T12046 |
arg1Of |
binding,Sox6 |
R7917 |
T12047 |
T12048 |
arg1Of |
binding,to |
R7918 |
T12051 |
T12052 |
arg1Of |
promoter,and |
R7919 |
T12052 |
T12048 |
arg2Of |
and,to |
R7920 |
T12052 |
T12049 |
arg1Of |
and,the |
R7921 |
T12052 |
T12050 |
arg1Of |
and,ɛy |
R7922 |
T12052 |
T12054 |
arg1Of |
and,of |
R7923 |
T12052 |
T12057 |
arg1Of |
and,( |
R7924 |
T12053 |
T12052 |
arg2Of |
repression,and |
R7925 |
T12056 |
T12054 |
arg2Of |
activity,of |
R7926 |
T12056 |
T12055 |
arg1Of |
activity,its |
R7927 |
T12059 |
T12058 |
arg1Of |
3E,Figure |
R7928 |
T12059 |
T12060 |
arg1Of |
3E,and |
R7929 |
T12060 |
T12057 |
arg2Of |
and,( |
R7930 |
T12061 |
T12060 |
arg2Of |
3F,and |
R7931 |
T12062 |
T12057 |
arg3Of |
),( |
R7932 |
T12064 |
T12063 |
arg1Of |
observations,These |
R7933 |
T12064 |
T12065 |
arg1Of |
observations,suggest |
R7934 |
T12067 |
T12068 |
arg1Of |
Sox6,binds |
R7935 |
T12068 |
T12065 |
arg2Of |
binds,suggest |
R7936 |
T12068 |
T12066 |
arg1Of |
binds,that |
R7937 |
T12068 |
T12069 |
arg1Of |
binds,to |
R7938 |
T12068 |
T12077 |
arg1Of |
binds,as |
R7939 |
T12068 |
T12081 |
arg1Of |
binds,as |
R7940 |
T12071 |
T12069 |
arg2Of |
sequence,to |
R7941 |
T12071 |
T12070 |
arg1Of |
sequence,this |
R7942 |
T12071 |
T12072 |
arg1Of |
sequence,of |
R7943 |
T12075 |
T12072 |
arg2Of |
promoter,of |
R7944 |
T12075 |
T12073 |
arg1Of |
promoter,the |
R7945 |
T12075 |
T12074 |
arg1Of |
promoter,ɛy |
R7946 |
T12077 |
T12080 |
arg1Of |
as,or |
R7947 |
T12079 |
T12077 |
arg2Of |
homodimer,as |
R7948 |
T12079 |
T12078 |
arg1Of |
homodimer,a |
R7949 |
T12080 |
T12076 |
arg1Of |
or,either |
R7950 |
T12081 |
T12080 |
arg2Of |
as,or |
R7951 |
T12083 |
T12081 |
arg2Of |
heterodimer,as |
R7952 |
T12083 |
T12082 |
arg1Of |
heterodimer,a |
R7953 |
T12083 |
T12084 |
arg1Of |
heterodimer,with |
R7954 |
T12087 |
T12084 |
arg2Of |
proteins,with |
R7955 |
T12087 |
T12085 |
arg1Of |
proteins,other |
R7956 |
T12087 |
T12086 |
arg1Of |
proteins,Sox |
R7957 |
T12090 |
T12089 |
arg1Of |
proteins,Sox |
R7958 |
T12090 |
T12091 |
arg1Of |
proteins,recognize |
R7959 |
T12091 |
T12088 |
arg2Of |
recognize,Because |
R7960 |
T12096 |
T12091 |
arg2Of |
sequence,recognize |
R7961 |
T12096 |
T12092 |
arg1Of |
sequence,a |
R7962 |
T12096 |
T12093 |
arg1Of |
sequence,short |
R7963 |
T12096 |
T12094 |
arg1Of |
sequence,6-bp |
R7964 |
T12096 |
T12095 |
arg1Of |
sequence,core-binding |
R7965 |
T12096 |
T12097 |
arg1Of |
sequence,that |
R7966 |
T12096 |
T12098 |
arg1Of |
sequence,allows |
R7967 |
T12098 |
T12099 |
arg1Of |
allows,for |
R7968 |
T12101 |
T12099 |
arg2Of |
degeneracy,for |
R7969 |
T12101 |
T12100 |
arg1Of |
degeneracy,considerable |
R7970 |
T12104 |
T12103 |
arg1Of |
specificity,the |
R7971 |
T12104 |
T12105 |
arg1Of |
specificity,of |
R7972 |
T12104 |
T12108 |
arg1Of |
specificity,is |
R7973 |
T12104 |
T12109 |
arg2Of |
specificity,thought |
R7974 |
T12104 |
T12111 |
arg1Of |
specificity,rely |
R7975 |
T12107 |
T12105 |
arg2Of |
actions,of |
R7976 |
T12107 |
T12106 |
arg1Of |
actions,their |
R7977 |
T12109 |
T12088 |
arg1Of |
thought,Because |
R7978 |
T12109 |
T12102 |
arg1Of |
thought,"," |
R7979 |
T12109 |
T12108 |
arg2Of |
thought,is |
R7980 |
T12111 |
T12109 |
arg3Of |
rely,thought |
R7981 |
T12111 |
T12110 |
arg1Of |
rely,to |
R7982 |
T12111 |
T12112 |
arg1Of |
rely,upon |
R7983 |
T12113 |
T12112 |
arg2Of |
interactions,upon |
R7984 |
T12113 |
T12114 |
arg1Of |
interactions,with |
R7985 |
T12117 |
T12114 |
arg2Of |
factors,with |
R7986 |
T12117 |
T12115 |
arg1Of |
factors,other |
R7987 |
T12117 |
T12116 |
arg1Of |
factors,transcription |
R7988 |
T12117 |
T12118 |
arg1Of |
factors,[ |
R7989 |
T12119 |
T12118 |
arg2Of |
36,[ |
R7990 |
T12120 |
T12118 |
arg3Of |
],[ |
R7991 |
T12123 |
T12121 |
arg2Of |
EMSAs,In |
R7992 |
T12123 |
T12122 |
arg1Of |
EMSAs,our |
R7993 |
T12125 |
T12126 |
arg1Of |
we,had |
R7994 |
T12125 |
T12128 |
arg1Of |
we,run |
R7995 |
T12126 |
T12121 |
arg1Of |
had,In |
R7996 |
T12126 |
T12124 |
arg1Of |
had,"," |
R7997 |
T12128 |
T12126 |
arg2Of |
run,had |
R7998 |
T12128 |
T12127 |
arg1Of |
run,to |
R7999 |
T12128 |
T12131 |
arg1Of |
run,on |
R80 |
T289 |
T288 |
arg1Of |
testis,the |
R8000 |
T12128 |
T12138 |
arg1Of |
run,for |
R8001 |
T12128 |
T12143 |
modOf |
run,to |
R8002 |
T12128 |
T12148 |
arg1Of |
run,"," |
R8003 |
T12128 |
T12149 |
modOf |
run,suggesting |
R8004 |
T12130 |
T12128 |
arg2Of |
electrophoresis,run |
R8005 |
T12130 |
T12129 |
arg1Of |
electrophoresis,the |
R8006 |
T12135 |
T12136 |
arg1Of |
–6,% |
R8007 |
T12137 |
T12131 |
arg2Of |
gel,on |
R8008 |
T12137 |
T12132 |
arg1Of |
gel,a |
R8009 |
T12137 |
T12133 |
arg1Of |
gel,4 |
R8010 |
T12137 |
T12134 |
arg1Of |
gel,% |
R8011 |
T12137 |
T12135 |
arg1Of |
gel,–6 |
R8012 |
T12141 |
T12139 |
arg1Of |
4–8,at |
R8013 |
T12141 |
T12140 |
arg1Of |
4–8,least |
R8014 |
T12142 |
T12138 |
arg2Of |
h,for |
R8015 |
T12142 |
T12141 |
arg1Of |
h,4–8 |
R8016 |
T12144 |
T12143 |
arg1Of |
detect,to |
R8017 |
T12147 |
T12144 |
arg2Of |
band,detect |
R8018 |
T12147 |
T12145 |
arg1Of |
band,the |
R8019 |
T12147 |
T12146 |
arg1Of |
band,Sox6-associated |
R8020 |
T12151 |
T12152 |
arg1Of |
Sox6,is |
R8021 |
T12152 |
T12149 |
arg2Of |
is,suggesting |
R8022 |
T12152 |
T12150 |
arg1Of |
is,that |
R8023 |
T12153 |
T12152 |
arg2Of |
part,is |
R8024 |
T12153 |
T12154 |
arg1Of |
part,of |
R8025 |
T12159 |
T12154 |
arg2Of |
complex,of |
R8026 |
T12159 |
T12155 |
arg1Of |
complex,a |
R8027 |
T12159 |
T12156 |
arg1Of |
complex,high |
R8028 |
T12159 |
T12157 |
arg1Of |
complex,molecular |
R8029 |
T12159 |
T12158 |
arg1Of |
complex,weight |
R803 |
T1699 |
T1696 |
arg1Of |
box,Sry |
R8030 |
T12165 |
T12160 |
arg1Of |
repressors,A |
R8031 |
T12165 |
T12161 |
arg1Of |
repressors,few |
R8032 |
T12165 |
T12162 |
arg1Of |
repressors,other |
R8033 |
T12165 |
T12163 |
arg1Of |
repressors,ɛy |
R8034 |
T12165 |
T12164 |
arg1Of |
repressors,globin |
R8035 |
T12165 |
T12166 |
arg1Of |
repressors,have |
R8036 |
T12165 |
T12167 |
arg1Of |
repressors,been |
R8037 |
T12165 |
T12168 |
arg2Of |
repressors,reported |
R8038 |
T12165 |
T12170 |
arg1Of |
repressors,bind |
R8039 |
T12168 |
T12166 |
arg2Of |
reported,have |
R804 |
T1699 |
T1697 |
arg1Of |
box,type |
R8040 |
T12168 |
T12167 |
arg2Of |
reported,been |
R8041 |
T12170 |
T12168 |
arg3Of |
bind,reported |
R8042 |
T12170 |
T12169 |
arg1Of |
bind,to |
R8043 |
T12170 |
T12171 |
arg1Of |
bind,to |
R8044 |
T12173 |
T12171 |
arg2Of |
sequences,to |
R8045 |
T12173 |
T12172 |
arg1Of |
sequences,DNA |
R8046 |
T12173 |
T12174 |
arg1Of |
sequences,near |
R8047 |
T12178 |
T12174 |
arg2Of |
sites,near |
R8048 |
T12178 |
T12175 |
arg1Of |
sites,the |
R8049 |
T12178 |
T12176 |
arg1Of |
sites,Sox/Sox6 |
R805 |
T1699 |
T1698 |
arg1Of |
box,HMG |
R8050 |
T12178 |
T12177 |
arg1Of |
sites,consensus |
R8051 |
T12178 |
T12179 |
arg1Of |
sites,"," |
R8052 |
T12178 |
T12180 |
arg1Of |
sites,including |
R8053 |
T12183 |
T12181 |
arg1Of |
complex,the |
R8054 |
T12183 |
T12182 |
arg1Of |
complex,DRED |
R8055 |
T12183 |
T12184 |
arg1Of |
complex,[ |
R8056 |
T12183 |
T12187 |
arg1Of |
complex,and |
R8057 |
T12185 |
T12184 |
arg2Of |
37,[ |
R8058 |
T12186 |
T12184 |
arg3Of |
],[ |
R8059 |
T12187 |
T12180 |
arg2Of |
and,including |
R806 |
T1699 |
T1700 |
arg1Of |
box,( |
R8060 |
T12188 |
T12187 |
arg2Of |
COUP-TF,and |
R8061 |
T12188 |
T12189 |
arg1Of |
COUP-TF,[ |
R8062 |
T12190 |
T12189 |
arg2Of |
38,[ |
R8063 |
T12191 |
T12189 |
arg3Of |
],[ |
R8064 |
T12192 |
T12193 |
arg1Of |
Sox6,might |
R8065 |
T12192 |
T12194 |
arg1Of |
Sox6,interact |
R8066 |
T12192 |
T12199 |
arg1Of |
Sox6,form |
R8067 |
T12194 |
T12195 |
arg1Of |
interact,with |
R8068 |
T12194 |
T12198 |
arg1Of |
interact,and |
R8069 |
T12197 |
T12195 |
arg2Of |
factors,with |
R807 |
T1699 |
T1703 |
arg1Of |
box,is |
R8070 |
T12197 |
T12196 |
arg1Of |
factors,these |
R8071 |
T12198 |
T12193 |
arg2Of |
and,might |
R8072 |
T12199 |
T12198 |
arg2Of |
form,and |
R8073 |
T12203 |
T12199 |
arg2Of |
complex,form |
R8074 |
T12203 |
T12200 |
arg1Of |
complex,a |
R8075 |
T12203 |
T12201 |
arg1Of |
complex,large |
R8076 |
T12203 |
T12202 |
arg1Of |
complex,repression |
R8077 |
T12204 |
T12205 |
arg1Of |
Identification,of |
R8078 |
T12204 |
T12217 |
arg1Of |
Identification,will |
R8079 |
T12204 |
T12218 |
arg1Of |
Identification,shed |
R808 |
T1701 |
T1700 |
arg2Of |
Sox6,( |
R8080 |
T12207 |
T12205 |
arg2Of |
components,of |
R8081 |
T12207 |
T12206 |
arg1Of |
components,other |
R8082 |
T12207 |
T12208 |
arg1Of |
components,of |
R8083 |
T12211 |
T12208 |
arg2Of |
complex,of |
R8084 |
T12211 |
T12209 |
arg1Of |
complex,the |
R8085 |
T12211 |
T12210 |
arg1Of |
complex,Sox6-containing |
R8086 |
T12211 |
T12212 |
arg2Of |
complex,associated |
R8087 |
T12212 |
T12213 |
arg1Of |
associated,with |
R8088 |
T12216 |
T12213 |
arg2Of |
promoter,with |
R8089 |
T12216 |
T12214 |
arg1Of |
promoter,the |
R809 |
T1702 |
T1700 |
arg3Of |
),( |
R8090 |
T12216 |
T12215 |
arg1Of |
promoter,ɛy |
R8091 |
T12218 |
T12217 |
arg2Of |
shed,will |
R8092 |
T12218 |
T12220 |
arg1Of |
shed,on |
R8093 |
T12219 |
T12218 |
arg2Of |
light,shed |
R8094 |
T12222 |
T12220 |
arg2Of |
mechanism,on |
R8095 |
T12222 |
T12221 |
arg1Of |
mechanism,its |
R8096 |
T12222 |
T12223 |
arg1Of |
mechanism,of |
R8097 |
T12224 |
T12223 |
arg2Of |
repression,of |
R8098 |
T12226 |
T12225 |
arg1Of |
proteins,Sox |
R8099 |
T12226 |
T12227 |
arg1Of |
proteins,bind |
R81 |
T289 |
T290 |
arg1Of |
testis,determining |
R810 |
T1705 |
T1703 |
arg2Of |
member,is |
R8100 |
T12226 |
T12229 |
arg1Of |
proteins,bend |
R8101 |
T12226 |
T12241 |
arg1Of |
proteins,can |
R8102 |
T12226 |
T12243 |
arg1Of |
proteins,bind |
R8103 |
T12227 |
T12228 |
arg1Of |
bind,and |
R8104 |
T12228 |
T12240 |
arg1Of |
and,and |
R8105 |
T12229 |
T12228 |
arg2Of |
bend,and |
R8106 |
T12231 |
T12227 |
arg2Of |
DNA,bind |
R8107 |
T12231 |
T12229 |
arg2Of |
DNA,bend |
R8108 |
T12231 |
T12230 |
arg1Of |
DNA,linear |
R8109 |
T12231 |
T12232 |
arg1Of |
DNA,by |
R811 |
T1705 |
T1704 |
arg1Of |
member,a |
R8110 |
T12234 |
T12232 |
arg2Of |
intercalation,by |
R8111 |
T12234 |
T12233 |
arg1Of |
intercalation,partial |
R8112 |
T12234 |
T12235 |
arg1Of |
intercalation,in |
R8113 |
T12238 |
T12235 |
arg2Of |
groove,in |
R8114 |
T12238 |
T12236 |
arg1Of |
groove,the |
R8115 |
T12238 |
T12237 |
arg1Of |
groove,minor |
R8116 |
T12240 |
T12239 |
arg1Of |
and,"," |
R8117 |
T12243 |
T12240 |
arg2Of |
bind,and |
R8118 |
T12243 |
T12241 |
arg2Of |
bind,can |
R8119 |
T12243 |
T12242 |
arg1Of |
bind,also |
R812 |
T1705 |
T1706 |
arg1Of |
member,of |
R8120 |
T12243 |
T12244 |
arg1Of |
bind,to |
R8121 |
T12246 |
T12244 |
arg2Of |
junctions,to |
R8122 |
T12246 |
T12245 |
arg1Of |
junctions,four-way |
R8123 |
T12246 |
T12247 |
arg1Of |
junctions,[ |
R8124 |
T12248 |
T12247 |
arg2Of |
2–4,[ |
R8125 |
T12249 |
T12247 |
arg3Of |
],[ |
R8126 |
T12254 |
T12252 |
arg1Of |
model,one |
R8127 |
T12254 |
T12253 |
arg1Of |
model,attractive |
R8128 |
T12254 |
T12255 |
modOf |
model,to |
R8129 |
T12254 |
T12263 |
arg1Of |
model,is |
R813 |
T1711 |
T1706 |
arg2Of |
family,of |
R8130 |
T12256 |
T12255 |
arg1Of |
explain,to |
R8131 |
T12257 |
T12256 |
arg2Of |
how,explain |
R8132 |
T12259 |
T12258 |
arg1Of |
proteins,Sox6 |
R8133 |
T12259 |
T12260 |
arg1Of |
proteins,control |
R8134 |
T12260 |
T12257 |
arg1Of |
control,how |
R8135 |
T12262 |
T12260 |
arg2Of |
expression,control |
R8136 |
T12262 |
T12261 |
arg1Of |
expression,gene |
R8137 |
T12263 |
T12250 |
arg1Of |
is,Therefore |
R8138 |
T12263 |
T12251 |
arg1Of |
is,"," |
R8139 |
T12265 |
T12266 |
arg1Of |
they,function |
R814 |
T1711 |
T1707 |
arg1Of |
family,the |
R8140 |
T12266 |
T12263 |
arg2Of |
function,is |
R8141 |
T12266 |
T12264 |
arg1Of |
function,that |
R8142 |
T12266 |
T12267 |
arg1Of |
function,as |
R8143 |
T12269 |
T12268 |
arg1Of |
factors,architectural |
R8144 |
T12269 |
T12270 |
arg1Of |
factors,bound |
R8145 |
T12269 |
T12274 |
arg1Of |
factors,influencing |
R8146 |
T12269 |
T12279 |
arg1Of |
factors,bending |
R8147 |
T12270 |
T12267 |
arg2Of |
bound,as |
R8148 |
T12270 |
T12271 |
arg1Of |
bound,to |
R8149 |
T12270 |
T12273 |
arg1Of |
bound,"," |
R815 |
T1711 |
T1708 |
arg1Of |
family,Sox |
R8150 |
T12270 |
T12274 |
modOf |
bound,influencing |
R8151 |
T12272 |
T12271 |
arg2Of |
DNA,to |
R8152 |
T12274 |
T12278 |
arg1Of |
influencing,by |
R8153 |
T12274 |
T12282 |
arg1Of |
influencing,by |
R8154 |
T12277 |
T12274 |
arg2Of |
structure,influencing |
R8155 |
T12277 |
T12275 |
arg1Of |
structure,local |
R8156 |
T12277 |
T12276 |
arg1Of |
structure,chromatin |
R8157 |
T12278 |
T12281 |
arg1Of |
by,and |
R8158 |
T12279 |
T12278 |
arg2Of |
bending,by |
R8159 |
T12280 |
T12279 |
arg2Of |
DNA,bending |
R816 |
T1711 |
T1709 |
arg1Of |
family,transcription |
R8160 |
T12282 |
T12281 |
arg2Of |
by,and |
R8161 |
T12283 |
T12282 |
arg2Of |
assembling,by |
R8162 |
T12286 |
T12283 |
arg2Of |
complexes,assembling |
R8163 |
T12286 |
T12284 |
arg1Of |
complexes,multiprotein |
R8164 |
T12286 |
T12285 |
arg1Of |
complexes,transcriptional |
R8165 |
T12288 |
T12287 |
arg2Of |
changing,By |
R8166 |
T12292 |
T12288 |
arg2Of |
structure,changing |
R8167 |
T12292 |
T12289 |
arg1Of |
structure,the |
R8168 |
T12292 |
T12290 |
arg1Of |
structure,local |
R8169 |
T12292 |
T12291 |
arg1Of |
structure,chromatin |
R817 |
T1711 |
T1710 |
arg1Of |
family,factor |
R8170 |
T12294 |
T12288 |
arg1Of |
Sox6,changing |
R8171 |
T12294 |
T12295 |
arg1Of |
Sox6,could |
R8172 |
T12294 |
T12297 |
arg1Of |
Sox6,interfere |
R8173 |
T12294 |
T12307 |
arg1Of |
Sox6,facilitate |
R8174 |
T12297 |
T12298 |
arg1Of |
interfere,with |
R8175 |
T12297 |
T12306 |
arg1Of |
interfere,or |
R8176 |
T12299 |
T12298 |
arg2Of |
binding,with |
R8177 |
T12299 |
T12300 |
arg1Of |
binding,of |
R8178 |
T12299 |
T12303 |
arg1Of |
binding,to |
R8179 |
T12302 |
T12300 |
arg2Of |
activators,of |
R818 |
T1711 |
T1712 |
arg2Of |
family,characterized |
R8180 |
T12302 |
T12301 |
arg1Of |
activators,other |
R8181 |
T12305 |
T12303 |
arg2Of |
promoter,to |
R8182 |
T12305 |
T12304 |
arg1Of |
promoter,the |
R8183 |
T12306 |
T12287 |
arg1Of |
or,By |
R8184 |
T12306 |
T12293 |
arg1Of |
or,"," |
R8185 |
T12306 |
T12295 |
arg2Of |
or,could |
R8186 |
T12306 |
T12296 |
arg1Of |
or,either |
R8187 |
T12307 |
T12306 |
arg2Of |
facilitate,or |
R8188 |
T12308 |
T12307 |
arg2Of |
binding,facilitate |
R8189 |
T12308 |
T12309 |
arg1Of |
binding,of |
R819 |
T1720 |
T1719 |
arg2Of |
HMG,( |
R8190 |
T12311 |
T12309 |
arg2Of |
repressors,of |
R8191 |
T12311 |
T12310 |
arg1Of |
repressors,other |
R8192 |
T12313 |
T12312 |
arg1Of |
example,Another |
R8193 |
T12313 |
T12314 |
arg1Of |
example,of |
R8194 |
T12313 |
T12326 |
arg1Of |
example,is |
R8195 |
T12313 |
T12327 |
arg2Of |
example,DRED |
R8196 |
T12316 |
T12314 |
arg2Of |
repressor,of |
R8197 |
T12316 |
T12315 |
arg1Of |
repressor,a |
R8198 |
T12316 |
T12317 |
arg1Of |
repressor,that |
R8199 |
T12316 |
T12318 |
arg1Of |
repressor,interferes |
R82 |
T291 |
T290 |
arg2Of |
gene,determining |
R820 |
T1721 |
T1719 |
arg3Of |
),( |
R8200 |
T12318 |
T12319 |
arg1Of |
interferes,with |
R8201 |
T12318 |
T12322 |
arg1Of |
interferes,on |
R8202 |
T12321 |
T12319 |
arg2Of |
activator,with |
R8203 |
T12321 |
T12320 |
arg1Of |
activator,an |
R8204 |
T12325 |
T12322 |
arg2Of |
promoter,on |
R8205 |
T12325 |
T12323 |
arg1Of |
promoter,the |
R8206 |
T12325 |
T12324 |
arg1Of |
promoter,ɛy |
R8207 |
T12327 |
T12326 |
arg2Of |
DRED,is |
R8208 |
T12328 |
T12329 |
arg1Of |
DRED,interferes |
R8209 |
T12328 |
T12337 |
arg1Of |
DRED,binding |
R821 |
T1722 |
T1712 |
arg1Of |
domain,characterized |
R8210 |
T12329 |
T12330 |
arg1Of |
interferes,with |
R8211 |
T12329 |
T12335 |
arg1Of |
interferes,"," |
R8212 |
T12329 |
T12336 |
arg1Of |
interferes,in |
R8213 |
T12331 |
T12330 |
arg2Of |
EKLF,with |
R8214 |
T12331 |
T12332 |
arg1Of |
EKLF,"," |
R8215 |
T12334 |
T12332 |
arg2Of |
activator,"," |
R8216 |
T12334 |
T12333 |
arg1Of |
activator,an |
R8217 |
T12337 |
T12336 |
arg2Of |
binding,in |
R8218 |
T12337 |
T12338 |
arg1Of |
binding,to |
R8219 |
T12341 |
T12338 |
arg2Of |
promoter,to |
R822 |
T1722 |
T1713 |
arg2Of |
domain,by |
R8220 |
T12341 |
T12339 |
arg1Of |
promoter,the |
R8221 |
T12341 |
T12340 |
arg1Of |
promoter,ɛy |
R8222 |
T12341 |
T12342 |
arg1Of |
promoter,[ |
R8223 |
T12343 |
T12342 |
arg2Of |
39,[ |
R8224 |
T12344 |
T12342 |
arg3Of |
],[ |
R8225 |
T12348 |
T12345 |
arg1Of |
proteins,Two |
R8226 |
T12348 |
T12346 |
arg1Of |
proteins,HMG |
R8227 |
T12348 |
T12347 |
arg1Of |
proteins,architectural |
R8228 |
T12348 |
T12349 |
arg1Of |
proteins,( |
R8229 |
T12348 |
T12360 |
arg1Of |
proteins,"," |
R823 |
T1722 |
T1714 |
arg1Of |
domain,the |
R8230 |
T12351 |
T12349 |
arg2Of |
related,( |
R8231 |
T12351 |
T12350 |
arg1Of |
related,distantly |
R8232 |
T12351 |
T12352 |
arg1Of |
related,to |
R8233 |
T12355 |
T12352 |
arg2Of |
family,to |
R8234 |
T12355 |
T12353 |
arg1Of |
family,the |
R8235 |
T12355 |
T12354 |
arg1Of |
family,Sox |
R8236 |
T12355 |
T12356 |
arg1Of |
family,of |
R8237 |
T12358 |
T12356 |
arg2Of |
factors,of |
R8238 |
T12358 |
T12357 |
arg1Of |
factors,transcription |
R8239 |
T12359 |
T12349 |
arg3Of |
),( |
R824 |
T1722 |
T1715 |
arg2Of |
domain,conserved |
R8240 |
T12360 |
T12365 |
arg1Of |
",",were |
R8241 |
T12360 |
T12366 |
arg2Of |
",",demonstrated |
R8242 |
T12360 |
T12368 |
arg1Of |
",",bind |
R8243 |
T12360 |
T12383 |
arg1Of |
",",cause |
R8244 |
T12361 |
T12362 |
arg1Of |
HMG-I,and |
R8245 |
T12362 |
T12360 |
arg2Of |
and,"," |
R8246 |
T12363 |
T12362 |
arg2Of |
HMG-Y,and |
R8247 |
T12366 |
T12365 |
arg2Of |
demonstrated,were |
R8248 |
T12366 |
T12382 |
arg1Of |
demonstrated,and |
R8249 |
T12368 |
T12366 |
arg3Of |
bind,demonstrated |
R825 |
T1722 |
T1716 |
arg1Of |
domain,high |
R8250 |
T12368 |
T12367 |
arg1Of |
bind,to |
R8251 |
T12368 |
T12369 |
arg1Of |
bind,to |
R8252 |
T12375 |
T12369 |
arg2Of |
silencers,to |
R8253 |
T12375 |
T12370 |
arg1Of |
silencers,the |
R8254 |
T12375 |
T12371 |
arg1Of |
silencers,human |
R8255 |
T12375 |
T12372 |
arg1Of |
silencers,adult |
R8256 |
T12375 |
T12373 |
arg1Of |
silencers,β |
R8257 |
T12375 |
T12374 |
arg1Of |
silencers,globin |
R8258 |
T12375 |
T12376 |
arg1Of |
silencers,( |
R8259 |
T12378 |
T12379 |
arg1Of |
I,and |
R826 |
T1722 |
T1717 |
arg1Of |
domain,mobility |
R8260 |
T12379 |
T12376 |
arg2Of |
and,( |
R8261 |
T12379 |
T12377 |
arg1Of |
and,silencers |
R8262 |
T12380 |
T12379 |
arg2Of |
II,and |
R8263 |
T12381 |
T12376 |
arg3Of |
),( |
R8264 |
T12382 |
T12364 |
arg1Of |
and,"," |
R8265 |
T12382 |
T12395 |
arg1Of |
and,[ |
R8266 |
T12383 |
T12382 |
arg2Of |
cause,and |
R8267 |
T12384 |
T12383 |
arg2Of |
bending,cause |
R8268 |
T12384 |
T12385 |
arg1Of |
bending,of |
R8269 |
T12384 |
T12388 |
arg1Of |
bending,"," |
R827 |
T1722 |
T1718 |
arg1Of |
domain,group |
R8270 |
T12387 |
T12385 |
arg2Of |
DNA,of |
R8271 |
T12387 |
T12386 |
arg1Of |
DNA,the |
R8272 |
T12389 |
T12388 |
arg2Of |
facilitating,"," |
R8273 |
T12391 |
T12389 |
arg2Of |
binding,facilitating |
R8274 |
T12391 |
T12390 |
arg1Of |
binding,the |
R8275 |
T12391 |
T12392 |
arg1Of |
binding,of |
R8276 |
T12394 |
T12392 |
arg2Of |
repressors,of |
R8277 |
T12394 |
T12393 |
arg1Of |
repressors,other |
R8278 |
T12396 |
T12395 |
arg2Of |
40,[ |
R8279 |
T12397 |
T12395 |
arg3Of |
],[ |
R828 |
T1722 |
T1719 |
arg1Of |
domain,( |
R8280 |
T12399 |
T12398 |
arg1Of |
expression,Sox6 |
R8281 |
T12399 |
T12400 |
arg1Of |
expression,is |
R8282 |
T12399 |
T12404 |
arg1Of |
expression,coincident |
R8283 |
T12400 |
T12418 |
arg1Of |
is,and |
R8284 |
T12401 |
T12402 |
arg1Of |
temporally,and |
R8285 |
T12403 |
T12402 |
arg2Of |
spatially,and |
R8286 |
T12404 |
T12400 |
arg2Of |
coincident,is |
R8287 |
T12404 |
T12401 |
arg1Of |
coincident,temporally |
R8288 |
T12404 |
T12403 |
arg1Of |
coincident,spatially |
R8289 |
T12404 |
T12405 |
arg1Of |
coincident,with |
R829 |
T1722 |
T1723 |
arg1Of |
domain,"," |
R8290 |
T12406 |
T12407 |
arg1Of |
definitive,( |
R8291 |
T12410 |
T12407 |
arg2Of |
primitive,( |
R8292 |
T12410 |
T12408 |
arg1Of |
primitive,but |
R8293 |
T12410 |
T12409 |
arg1Of |
primitive,not |
R8294 |
T12411 |
T12407 |
arg3Of |
),( |
R8295 |
T12412 |
T12405 |
arg2Of |
erythropoiesis,with |
R8296 |
T12412 |
T12406 |
arg1Of |
erythropoiesis,definitive |
R8297 |
T12412 |
T12413 |
arg1Of |
erythropoiesis,( |
R8298 |
T12414 |
T12413 |
arg2Of |
Figure,( |
R8299 |
T12414 |
T12415 |
arg1Of |
Figure,6 |
R83 |
T291 |
T296 |
modOf |
gene,have |
R830 |
T1722 |
T1724 |
arg1Of |
domain,consisting |
R8300 |
T12416 |
T12413 |
arg3Of |
),( |
R8301 |
T12418 |
T12417 |
arg1Of |
and,"," |
R8302 |
T12419 |
T12420 |
arg1Of |
Sox6,represses |
R8303 |
T12420 |
T12418 |
arg2Of |
represses,and |
R8304 |
T12423 |
T12421 |
arg1Of |
expression,ɛy |
R8305 |
T12423 |
T12422 |
arg1Of |
expression,globin |
R8306 |
T12423 |
T12426 |
arg1Of |
expression,vivo |
R8307 |
T12423 |
T12427 |
arg1Of |
expression,( |
R8308 |
T12423 |
T12431 |
arg1Of |
expression,and |
R8309 |
T12426 |
T12424 |
arg1Of |
vivo,both |
R831 |
T1724 |
T1725 |
arg1Of |
consisting,of |
R8310 |
T12426 |
T12425 |
arg1Of |
vivo,in |
R8311 |
T12428 |
T12427 |
arg2Of |
Figure,( |
R8312 |
T12428 |
T12429 |
arg1Of |
Figure,1 |
R8313 |
T12430 |
T12427 |
arg3Of |
),( |
R8314 |
T12431 |
T12420 |
arg2Of |
and,represses |
R8315 |
T12433 |
T12432 |
arg1Of |
vitro,in |
R8316 |
T12435 |
T12431 |
arg2Of |
Figure,and |
R8317 |
T12435 |
T12433 |
arg1Of |
Figure,vitro |
R8318 |
T12435 |
T12434 |
arg2Of |
Figure,( |
R8319 |
T12435 |
T12436 |
arg1Of |
Figure,2 |
R832 |
T1728 |
T1725 |
arg2Of |
acids,of |
R8320 |
T12437 |
T12434 |
arg3Of |
),( |
R8321 |
T12441 |
T12440 |
arg1Of |
situ,in |
R8322 |
T12442 |
T12441 |
arg1Of |
hybridization,situ |
R8323 |
T12442 |
T12444 |
arg1Of |
hybridization,shows |
R8324 |
T12444 |
T12438 |
arg1Of |
shows,Moreover |
R8325 |
T12444 |
T12439 |
arg1Of |
shows,"," |
R8326 |
T12444 |
T12443 |
arg1Of |
shows,clearly |
R8327 |
T12448 |
T12446 |
arg1Of |
expression,the |
R8328 |
T12448 |
T12447 |
arg1Of |
expression,persistent |
R8329 |
T12448 |
T12449 |
arg1Of |
expression,of |
R833 |
T1728 |
T1726 |
arg1Of |
acids,79 |
R8330 |
T12448 |
T12452 |
arg1Of |
expression,in |
R8331 |
T12448 |
T12456 |
arg1Of |
expression,is |
R8332 |
T12448 |
T12458 |
arg1Of |
expression,to |
R8333 |
T12451 |
T12449 |
arg2Of |
globin,of |
R8334 |
T12451 |
T12450 |
arg1Of |
globin,ɛy |
R8335 |
T12455 |
T12452 |
arg2Of |
mice,in |
R8336 |
T12455 |
T12453 |
arg1Of |
mice,p100H |
R8337 |
T12455 |
T12454 |
arg1Of |
mice,mutant |
R8338 |
T12456 |
T12444 |
arg2Of |
is,shows |
R8339 |
T12456 |
T12445 |
arg1Of |
is,that |
R834 |
T1728 |
T1727 |
arg1Of |
acids,amino |
R8340 |
T12458 |
T12456 |
arg2Of |
to,is |
R8341 |
T12458 |
T12457 |
arg1Of |
to,due |
R8342 |
T12459 |
T12458 |
arg2Of |
defects,to |
R8343 |
T12459 |
T12460 |
arg1Of |
defects,in |
R8344 |
T12463 |
T12460 |
arg2Of |
mechanism,in |
R8345 |
T12463 |
T12461 |
arg1Of |
mechanism,the |
R8346 |
T12463 |
T12462 |
arg1Of |
mechanism,silencing |
R8347 |
T12463 |
T12464 |
arg1Of |
mechanism,of |
R8348 |
T12463 |
T12467 |
arg1Of |
mechanism,that |
R8349 |
T12463 |
T12468 |
arg1Of |
mechanism,takes |
R835 |
T1728 |
T1729 |
arg2Of |
acids,involved |
R8350 |
T12466 |
T12464 |
arg2Of |
erythropoiesis,of |
R8351 |
T12466 |
T12465 |
arg1Of |
erythropoiesis,definitive |
R8352 |
T12468 |
T12470 |
arg1Of |
takes,in |
R8353 |
T12469 |
T12468 |
arg2Of |
place,takes |
R8354 |
T12472 |
T12470 |
arg2Of |
liver,in |
R8355 |
T12472 |
T12471 |
arg1Of |
liver,the |
R8356 |
T12472 |
T12473 |
arg1Of |
liver,( |
R8357 |
T12474 |
T12473 |
arg2Of |
Figure,( |
R8358 |
T12474 |
T12475 |
arg1Of |
Figure,5 |
R8359 |
T12476 |
T12473 |
arg3Of |
),( |
R836 |
T1729 |
T1730 |
arg1Of |
involved,in |
R8360 |
T12477 |
T12478 |
arg1Of |
Taken,together |
R8361 |
T12481 |
T12480 |
arg1Of |
data,these |
R8362 |
T12481 |
T12482 |
arg1Of |
data,demonstrate |
R8363 |
T12482 |
T12477 |
modOf |
demonstrate,Taken |
R8364 |
T12482 |
T12479 |
arg1Of |
demonstrate,"," |
R8365 |
T12485 |
T12482 |
arg2Of |
functions,demonstrate |
R8366 |
T12485 |
T12483 |
arg1Of |
functions,that |
R8367 |
T12485 |
T12484 |
arg1Of |
functions,Sox6 |
R8368 |
T12485 |
T12486 |
arg1Of |
functions,in |
R8369 |
T12488 |
T12486 |
arg2Of |
erythropoiesis,in |
R837 |
T1729 |
T1735 |
arg1Of |
involved,[ |
R8370 |
T12488 |
T12487 |
arg1Of |
erythropoiesis,definitive |
R8371 |
T12488 |
T12489 |
arg1Of |
erythropoiesis,to |
R8372 |
T12493 |
T12489 |
arg2Of |
expression,to |
R8373 |
T12493 |
T12490 |
arg1Of |
expression,silence |
R8374 |
T12493 |
T12491 |
arg1Of |
expression,ɛy |
R8375 |
T12493 |
T12492 |
arg1Of |
expression,globin |
R8376 |
T12496 |
T12494 |
arg1Of |
level,The |
R8377 |
T12496 |
T12495 |
arg1Of |
level,expression |
R8378 |
T12496 |
T12497 |
arg1Of |
level,of |
R8379 |
T12496 |
T12500 |
arg1Of |
level,in |
R838 |
T1732 |
T1733 |
arg1Of |
recognition,and |
R8380 |
T12496 |
T12511 |
arg1Of |
level,is |
R8381 |
T12496 |
T12513 |
arg1Of |
level,equivalent |
R8382 |
T12499 |
T12497 |
arg2Of |
globin,of |
R8383 |
T12499 |
T12498 |
arg1Of |
globin,ɛy |
R8384 |
T12504 |
T12500 |
arg2Of |
mice,in |
R8385 |
T12504 |
T12501 |
arg1Of |
mice,homozygous |
R8386 |
T12504 |
T12502 |
arg1Of |
mice,Sox6 |
R8387 |
T12504 |
T12503 |
arg1Of |
mice,null |
R8388 |
T12504 |
T12505 |
arg1Of |
mice,at |
R8389 |
T12507 |
T12506 |
arg1Of |
dpc,15.5 |
R839 |
T1733 |
T1730 |
arg2Of |
and,in |
R8390 |
T12507 |
T12508 |
arg1Of |
dpc,and |
R8391 |
T12508 |
T12505 |
arg2Of |
and,at |
R8392 |
T12510 |
T12508 |
arg2Of |
dpc,and |
R8393 |
T12510 |
T12509 |
arg1Of |
dpc,18.5 |
R8394 |
T12513 |
T12511 |
arg2Of |
equivalent,is |
R8395 |
T12513 |
T12512 |
arg1Of |
equivalent,statistically |
R8396 |
T12513 |
T12514 |
arg1Of |
equivalent,to |
R8397 |
T12516 |
T12514 |
arg2Of |
level,to |
R8398 |
T12516 |
T12515 |
arg1Of |
level,the |
R8399 |
T12516 |
T12517 |
arg1Of |
level,of |
R84 |
T294 |
T293 |
arg1Of |
Previous,Sry. |
R840 |
T1733 |
T1731 |
arg1Of |
and,DNA |
R8400 |
T12519 |
T12518 |
arg1Of |
expression,βmaj/min |
R8401 |
T12519 |
T12520 |
arg1Of |
expression,in |
R8402 |
T12519 |
T12525 |
arg1Of |
expression,and |
R8403 |
T12522 |
T12520 |
arg2Of |
livers,in |
R8404 |
T12522 |
T12521 |
arg1Of |
livers,the |
R8405 |
T12522 |
T12523 |
arg1Of |
livers,of |
R8406 |
T12524 |
T12523 |
arg2Of |
15.5-dpc,of |
R8407 |
T12525 |
T12517 |
arg2Of |
and,of |
R8408 |
T12529 |
T12525 |
arg2Of |
mice,and |
R8409 |
T12529 |
T12526 |
arg1Of |
mice,18.5-dpc |
R841 |
T1734 |
T1733 |
arg2Of |
binding,and |
R8410 |
T12529 |
T12527 |
arg1Of |
mice,homozygous |
R8411 |
T12529 |
T12528 |
arg1Of |
mice,WT |
R8412 |
T12529 |
T12530 |
arg1Of |
mice,( |
R8413 |
T12531 |
T12530 |
arg2Of |
Figure,( |
R8414 |
T12531 |
T12532 |
arg1Of |
Figure,1 |
R8415 |
T12533 |
T12530 |
arg3Of |
),( |
R8416 |
T12534 |
T12535 |
arg1Of |
This,demonstrates |
R8417 |
T12538 |
T12537 |
arg1Of |
expression,ectopic |
R8418 |
T12538 |
T12539 |
arg1Of |
expression,of |
R8419 |
T12538 |
T12544 |
arg1Of |
expression,is |
R842 |
T1736 |
T1735 |
arg2Of |
1,[ |
R8420 |
T12538 |
T12546 |
arg1Of |
expression,robust |
R8421 |
T12543 |
T12539 |
arg2Of |
gene,of |
R8422 |
T12543 |
T12540 |
arg1Of |
gene,the |
R8423 |
T12543 |
T12541 |
arg1Of |
gene,ɛy |
R8424 |
T12543 |
T12542 |
arg1Of |
gene,globin |
R8425 |
T12544 |
T12535 |
arg2Of |
is,demonstrates |
R8426 |
T12544 |
T12536 |
arg1Of |
is,that |
R8427 |
T12546 |
T12544 |
arg2Of |
robust,is |
R8428 |
T12546 |
T12545 |
arg1Of |
robust,quite |
R8429 |
T12546 |
T12547 |
arg1Of |
robust,in |
R843 |
T1737 |
T1735 |
arg3Of |
],[ |
R8430 |
T12550 |
T12547 |
arg2Of |
mice,in |
R8431 |
T12550 |
T12548 |
arg1Of |
mice,homozygous |
R8432 |
T12550 |
T12549 |
arg1Of |
mice,mutant |
R8433 |
T12553 |
T12551 |
arg1Of |
levels,The |
R8434 |
T12553 |
T12552 |
arg1Of |
levels,expression |
R8435 |
T12553 |
T12554 |
arg1Of |
levels,of |
R8436 |
T12553 |
T12565 |
arg1Of |
levels,are |
R8437 |
T12553 |
T12567 |
arg1Of |
levels,higher |
R8438 |
T12559 |
T12554 |
arg2Of |
genes,of |
R8439 |
T12559 |
T12555 |
arg1Of |
genes,two |
R844 |
T1740 |
T1738 |
arg1Of |
factors,Sox |
R8440 |
T12559 |
T12556 |
arg1Of |
genes,other |
R8441 |
T12559 |
T12557 |
arg1Of |
genes,embryonic |
R8442 |
T12559 |
T12558 |
arg1Of |
genes,globin |
R8443 |
T12559 |
T12560 |
arg1Of |
genes,( |
R8444 |
T12561 |
T12562 |
arg1Of |
ζ,and |
R8445 |
T12562 |
T12560 |
arg2Of |
and,( |
R8446 |
T12563 |
T12562 |
arg2Of |
βh1,and |
R8447 |
T12564 |
T12560 |
arg3Of |
),( |
R8448 |
T12565 |
T12566 |
arg1Of |
are,also |
R8449 |
T12565 |
T12571 |
arg1Of |
are,"," |
R845 |
T1740 |
T1739 |
arg1Of |
factors,transcription |
R8450 |
T12565 |
T12572 |
arg1Of |
are,compared |
R8451 |
T12567 |
T12565 |
arg2Of |
higher,are |
R8452 |
T12567 |
T12568 |
arg1Of |
higher,in |
R8453 |
T12570 |
T12568 |
arg2Of |
homozygotes,in |
R8454 |
T12570 |
T12569 |
arg1Of |
homozygotes,p100H |
R8455 |
T12573 |
T12572 |
arg2Of |
with,compared |
R8456 |
T12574 |
T12573 |
arg2Of |
WT,with |
R8457 |
T12576 |
T12575 |
arg2Of |
ɛy,Like |
R8458 |
T12578 |
T12579 |
arg1Of |
levels,of |
R8459 |
T12578 |
T12583 |
arg1Of |
levels,are |
R846 |
T1740 |
T1741 |
arg1Of |
factors,bind |
R8460 |
T12578 |
T12585 |
arg1Of |
levels,higher |
R8461 |
T12580 |
T12581 |
arg1Of |
ζ,and |
R8462 |
T12581 |
T12579 |
arg2Of |
and,of |
R8463 |
T12582 |
T12581 |
arg2Of |
βh1,and |
R8464 |
T12583 |
T12575 |
arg1Of |
are,Like |
R8465 |
T12583 |
T12577 |
arg1Of |
are,"," |
R8466 |
T12583 |
T12586 |
arg1Of |
are,in |
R8467 |
T12583 |
T12589 |
arg1Of |
are,at |
R8468 |
T12585 |
T12583 |
arg2Of |
higher,are |
R8469 |
T12585 |
T12584 |
arg1Of |
higher,dramatically |
R847 |
T1740 |
T1749 |
arg1Of |
factors,cause |
R8470 |
T12588 |
T12586 |
arg2Of |
mice,in |
R8471 |
T12588 |
T12587 |
arg1Of |
mice,mutant |
R8472 |
T12591 |
T12589 |
arg2Of |
dpc,at |
R8473 |
T12591 |
T12590 |
arg1Of |
dpc,15.5 |
R8474 |
T12596 |
T12594 |
arg2Of |
globin,unlike |
R8475 |
T12596 |
T12595 |
arg1Of |
globin,ɛy |
R8476 |
T12598 |
T12599 |
arg1Of |
ζ,and |
R8477 |
T12600 |
T12599 |
arg2Of |
βh1,and |
R8478 |
T12601 |
T12598 |
arg1Of |
decline,ζ |
R8479 |
T12601 |
T12600 |
arg1Of |
decline,βh1 |
R848 |
T1741 |
T1742 |
arg1Of |
bind,to |
R8480 |
T12601 |
T12602 |
arg1Of |
decline,in |
R8481 |
T12601 |
T12604 |
arg1Of |
decline,by |
R8482 |
T12601 |
T12612 |
arg1Of |
decline,"," |
R8483 |
T12601 |
T12613 |
arg1Of |
decline,suggesting |
R8484 |
T12603 |
T12602 |
arg2Of |
expression,in |
R8485 |
T12607 |
T12604 |
arg2Of |
dpc,by |
R8486 |
T12607 |
T12605 |
arg1Of |
dpc,day |
R8487 |
T12607 |
T12606 |
arg1Of |
dpc,18.5 |
R8488 |
T12607 |
T12608 |
arg1Of |
dpc,( |
R8489 |
T12609 |
T12608 |
arg2Of |
Figure,( |
R849 |
T1741 |
T1748 |
arg1Of |
bind,and |
R8490 |
T12609 |
T12610 |
arg1Of |
Figure,1 |
R8491 |
T12611 |
T12608 |
arg3Of |
),( |
R8492 |
T12613 |
T12592 |
arg1Of |
suggesting,However |
R8493 |
T12613 |
T12593 |
arg1Of |
suggesting,"," |
R8494 |
T12613 |
T12594 |
arg1Of |
suggesting,unlike |
R8495 |
T12613 |
T12597 |
arg1Of |
suggesting,"," |
R8496 |
T12615 |
T12616 |
arg1Of |
ɛy,is |
R8497 |
T12615 |
T12617 |
arg2Of |
ɛy,regulated |
R8498 |
T12617 |
T12613 |
arg2Of |
regulated,suggesting |
R8499 |
T12617 |
T12614 |
arg1Of |
regulated,that |
R85 |
T295 |
T294 |
arg1Of |
studies,Previous |
R850 |
T1745 |
T1742 |
arg2Of |
groove,to |
R8500 |
T12617 |
T12616 |
arg2Of |
regulated,is |
R8501 |
T12617 |
T12618 |
arg1Of |
regulated,differently |
R8502 |
T12618 |
T12619 |
arg1Of |
differently,than |
R8503 |
T12620 |
T12621 |
arg1Of |
ζ,and |
R8504 |
T12621 |
T12619 |
arg2Of |
and,than |
R8505 |
T12622 |
T12621 |
arg2Of |
βh1,and |
R8506 |
T12625 |
T12624 |
arg2Of |
possible,is |
R8507 |
T12627 |
T12628 |
arg1Of |
Sox6,has |
R8508 |
T12628 |
T12623 |
arg1Of |
has,It |
R8509 |
T12628 |
T12624 |
arg1Of |
has,is |
R851 |
T1745 |
T1743 |
arg1Of |
groove,the |
R8510 |
T12628 |
T12625 |
arg1Of |
has,possible |
R8511 |
T12628 |
T12626 |
arg1Of |
has,that |
R8512 |
T12628 |
T12632 |
arg1Of |
has,on |
R8513 |
T12628 |
T12641 |
arg1Of |
has,in |
R8514 |
T12631 |
T12628 |
arg2Of |
effect,has |
R8515 |
T12631 |
T12629 |
arg1Of |
effect,a |
R8516 |
T12631 |
T12630 |
arg1Of |
effect,general |
R8517 |
T12635 |
T12632 |
arg2Of |
genes,on |
R8518 |
T12635 |
T12633 |
arg1Of |
genes,embryonic |
R8519 |
T12635 |
T12634 |
arg1Of |
genes,globin |
R852 |
T1745 |
T1744 |
arg1Of |
groove,minor |
R8520 |
T12635 |
T12636 |
arg1Of |
genes,( |
R8521 |
T12639 |
T12636 |
arg2Of |
maturation,( |
R8522 |
T12639 |
T12637 |
arg1Of |
maturation,and |
R8523 |
T12639 |
T12638 |
arg1Of |
maturation,erythrocyte |
R8524 |
T12640 |
T12636 |
arg3Of |
),( |
R8525 |
T12642 |
T12641 |
arg2Of |
addition,in |
R8526 |
T12642 |
T12643 |
arg1Of |
addition,to |
R8527 |
T12646 |
T12643 |
arg2Of |
role,to |
R8528 |
T12646 |
T12644 |
arg1Of |
role,a |
R8529 |
T12646 |
T12645 |
arg1Of |
role,specific |
R853 |
T1745 |
T1746 |
arg1Of |
groove,of |
R8530 |
T12646 |
T12647 |
arg1Of |
role,in |
R8531 |
T12648 |
T12647 |
arg2Of |
silencing,in |
R8532 |
T12649 |
T12648 |
arg2Of |
ɛy,silencing |
R8533 |
T12651 |
T12650 |
arg2Of |
most,Although |
R8534 |
T12654 |
T12652 |
arg1Of |
mice,p100H |
R8535 |
T12654 |
T12653 |
arg1Of |
mice,mutant |
R8536 |
T12654 |
T12655 |
arg1Of |
mice,die |
R8537 |
T12654 |
T12658 |
arg1Of |
mice,being |
R8538 |
T12654 |
T12659 |
arg2Of |
mice,born |
R8539 |
T12655 |
T12650 |
arg1Of |
die,Although |
R854 |
T1747 |
T1746 |
arg2Of |
DNA,of |
R8540 |
T12655 |
T12656 |
arg1Of |
die,just |
R8541 |
T12655 |
T12657 |
arg1Of |
die,after |
R8542 |
T12655 |
T12660 |
arg1Of |
die,"," |
R8543 |
T12655 |
T12665 |
arg1Of |
die,longer |
R8544 |
T12659 |
T12657 |
arg2Of |
born,after |
R8545 |
T12659 |
T12658 |
arg2Of |
born,being |
R8546 |
T12664 |
T12661 |
arg1Of |
survive,a |
R8547 |
T12664 |
T12662 |
arg1Of |
survive,rare |
R8548 |
T12664 |
T12663 |
arg1Of |
survive,few |
R8549 |
T12665 |
T12664 |
arg1Of |
longer,survive |
R855 |
T1749 |
T1748 |
arg2Of |
cause,and |
R8550 |
T12666 |
T12667 |
arg1Of |
None,have |
R8551 |
T12666 |
T12668 |
arg1Of |
None,been |
R8552 |
T12666 |
T12669 |
arg2Of |
None,observed |
R8553 |
T12666 |
T12671 |
arg1Of |
None,live |
R8554 |
T12669 |
T12667 |
arg2Of |
observed,have |
R8555 |
T12669 |
T12668 |
arg2Of |
observed,been |
R8556 |
T12671 |
T12669 |
arg3Of |
live,observed |
R8557 |
T12671 |
T12670 |
arg1Of |
live,to |
R8558 |
T12671 |
T12676 |
arg1Of |
live,after |
R8559 |
T12671 |
T12678 |
arg1Of |
live,[ |
R856 |
T1752 |
T1749 |
arg2Of |
bend,cause |
R8560 |
T12672 |
T12673 |
arg1Of |
longer,than |
R8561 |
T12674 |
T12673 |
arg2Of |
2,than |
R8562 |
T12675 |
T12671 |
arg2Of |
wk,live |
R8563 |
T12675 |
T12672 |
arg1Of |
wk,longer |
R8564 |
T12677 |
T12676 |
arg2Of |
birth,after |
R8565 |
T12679 |
T12678 |
arg2Of |
14,[ |
R8566 |
T12680 |
T12678 |
arg3Of |
],[ |
R8567 |
T12681 |
T12682 |
arg1Of |
We,examined |
R8568 |
T12681 |
T12703 |
arg1Of |
We,detected |
R8569 |
T12682 |
T12702 |
arg1Of |
examined,and |
R857 |
T1752 |
T1750 |
arg1Of |
bend,a |
R8570 |
T12686 |
T12682 |
arg2Of |
sample,examined |
R8571 |
T12686 |
T12683 |
arg1Of |
sample,a |
R8572 |
T12686 |
T12684 |
arg1Of |
sample,single |
R8573 |
T12686 |
T12685 |
arg1Of |
sample,archived |
R8574 |
T12686 |
T12687 |
arg1Of |
sample,of |
R8575 |
T12686 |
T12694 |
arg1Of |
sample,on |
R8576 |
T12689 |
T12687 |
arg2Of |
RNA,of |
R8577 |
T12689 |
T12688 |
arg1Of |
RNA,liver |
R8578 |
T12689 |
T12690 |
arg1Of |
RNA,from |
R8579 |
T12693 |
T12690 |
arg2Of |
mouse,from |
R858 |
T1752 |
T1751 |
arg1Of |
bend,70°–85° |
R8580 |
T12693 |
T12691 |
arg1Of |
mouse,a |
R8581 |
T12693 |
T12692 |
arg1Of |
mouse,mutant |
R8582 |
T12696 |
T12694 |
arg2Of |
day,on |
R8583 |
T12696 |
T12695 |
arg1Of |
day,postnatal |
R8584 |
T12696 |
T12697 |
arg1Of |
day,13.5 |
R8585 |
T12696 |
T12698 |
arg1Of |
day,for |
R8586 |
T12701 |
T12698 |
arg2Of |
expression,for |
R8587 |
T12701 |
T12699 |
arg1Of |
expression,globin |
R8588 |
T12701 |
T12700 |
arg1Of |
expression,gene |
R8589 |
T12703 |
T12702 |
arg2Of |
detected,and |
R859 |
T1752 |
T1753 |
arg1Of |
bend,of |
R8590 |
T12703 |
T12709 |
arg1Of |
detected,in |
R8591 |
T12703 |
T12713 |
arg1Of |
detected,"," |
R8592 |
T12703 |
T12714 |
arg1Of |
detected,compared |
R8593 |
T12705 |
T12703 |
arg2Of |
levels,detected |
R8594 |
T12705 |
T12704 |
arg1Of |
levels,high |
R8595 |
T12705 |
T12706 |
arg1Of |
levels,of |
R8596 |
T12708 |
T12706 |
arg2Of |
globin,of |
R8597 |
T12708 |
T12707 |
arg1Of |
globin,ɛy |
R8598 |
T12712 |
T12709 |
arg2Of |
sample,in |
R8599 |
T12712 |
T12710 |
arg1Of |
sample,this |
R86 |
T295 |
T296 |
arg1Of |
studies,have |
R860 |
T1755 |
T1753 |
arg2Of |
DNA,of |
R8600 |
T12712 |
T12711 |
arg1Of |
sample,RNA |
R8601 |
T12715 |
T12714 |
arg2Of |
with,compared |
R8602 |
T12718 |
T12715 |
arg2Of |
RNA,with |
R8603 |
T12718 |
T12716 |
arg1Of |
RNA,undetectable |
R8604 |
T12718 |
T12717 |
arg1Of |
RNA,ɛy |
R8605 |
T12718 |
T12719 |
arg1Of |
RNA,in |
R8606 |
T12722 |
T12719 |
arg2Of |
mice,in |
R8607 |
T12722 |
T12720 |
arg1Of |
mice,WT |
R8608 |
T12722 |
T12721 |
arg1Of |
mice,control |
R8609 |
T12725 |
T12723 |
arg2Of |
point,At |
R861 |
T1755 |
T1754 |
arg1Of |
DNA,the |
R8610 |
T12725 |
T12724 |
arg1Of |
point,this |
R8611 |
T12725 |
T12726 |
arg1Of |
point,in |
R8612 |
T12727 |
T12726 |
arg2Of |
development,in |
R8613 |
T12730 |
T12729 |
arg1Of |
levels,the |
R8614 |
T12730 |
T12731 |
arg1Of |
levels,of |
R8615 |
T12730 |
T12736 |
arg1Of |
levels,were |
R8616 |
T12730 |
T12737 |
arg1Of |
levels,undetectable |
R8617 |
T12732 |
T12733 |
arg1Of |
ζ,and |
R8618 |
T12733 |
T12731 |
arg2Of |
and,of |
R8619 |
T12735 |
T12733 |
arg2Of |
RNA,and |
R862 |
T1755 |
T1756 |
arg1Of |
DNA,that |
R8620 |
T12735 |
T12734 |
arg1Of |
RNA,βh1 |
R8621 |
T12736 |
T12723 |
arg1Of |
were,At |
R8622 |
T12736 |
T12728 |
arg1Of |
were,"," |
R8623 |
T12736 |
T12743 |
arg1Of |
were,; |
R8624 |
T12737 |
T12736 |
arg2Of |
undetectable,were |
R8625 |
T12737 |
T12739 |
arg1Of |
undetectable,in |
R8626 |
T12739 |
T12738 |
arg1Of |
in,both |
R8627 |
T12740 |
T12741 |
arg1Of |
mutant,and |
R8628 |
T12741 |
T12739 |
arg2Of |
and,in |
R8629 |
T12742 |
T12741 |
arg2Of |
WT,and |
R863 |
T1755 |
T1757 |
arg1Of |
DNA,leads |
R8630 |
T12750 |
T12746 |
arg1Of |
levels,adult |
R8631 |
T12750 |
T12747 |
arg1Of |
levels,β-like |
R8632 |
T12750 |
T12748 |
arg1Of |
levels,globin |
R8633 |
T12750 |
T12749 |
arg1Of |
levels,RNA |
R8634 |
T12750 |
T12751 |
arg1Of |
levels,were |
R8635 |
T12750 |
T12753 |
arg1Of |
levels,elevated |
R8636 |
T12751 |
T12743 |
arg2Of |
were,; |
R8637 |
T12751 |
T12744 |
arg1Of |
were,however |
R8638 |
T12751 |
T12745 |
arg1Of |
were,"," |
R8639 |
T12751 |
T12758 |
arg1Of |
were,compared |
R864 |
T1757 |
T1758 |
arg1Of |
leads,to |
R8640 |
T12753 |
T12751 |
arg2Of |
elevated,were |
R8641 |
T12753 |
T12752 |
arg1Of |
elevated,moderately |
R8642 |
T12753 |
T12754 |
arg1Of |
elevated,in |
R8643 |
T12757 |
T12754 |
arg2Of |
RNA,in |
R8644 |
T12757 |
T12755 |
arg1Of |
RNA,the |
R8645 |
T12757 |
T12756 |
arg1Of |
RNA,mutant |
R8646 |
T12759 |
T12758 |
arg2Of |
with,compared |
R8647 |
T12760 |
T12759 |
arg2Of |
WT,with |
R8648 |
T12760 |
T12761 |
arg1Of |
WT,( |
R8649 |
T12760 |
T12765 |
arg1Of |
WT,"," |
R865 |
T1757 |
T1765 |
arg1Of |
leads,"," |
R8650 |
T12760 |
T12766 |
arg1Of |
WT,similar |
R8651 |
T12763 |
T12761 |
arg2Of |
data,( |
R8652 |
T12763 |
T12762 |
arg1Of |
data,unpublished |
R8653 |
T12764 |
T12761 |
arg3Of |
),( |
R8654 |
T12766 |
T12767 |
arg1Of |
similar,to |
R8655 |
T12768 |
T12767 |
arg2Of |
what,to |
R8656 |
T12768 |
T12770 |
arg2Of |
what,observe |
R8657 |
T12769 |
T12770 |
arg1Of |
we,observe |
R8658 |
T12770 |
T12771 |
arg1Of |
observe,at |
R8659 |
T12773 |
T12771 |
arg2Of |
dpc,at |
R866 |
T1757 |
T1766 |
arg1Of |
leads,while |
R8660 |
T12773 |
T12772 |
arg1Of |
dpc,18.5 |
R8661 |
T12773 |
T12774 |
arg1Of |
dpc,( |
R8662 |
T12775 |
T12774 |
arg2Of |
Figure,( |
R8663 |
T12775 |
T12776 |
arg1Of |
Figure,1 |
R8664 |
T12777 |
T12774 |
arg3Of |
),( |
R8665 |
T12779 |
T12778 |
arg1Of |
findings,These |
R8666 |
T12779 |
T12780 |
arg1Of |
findings,suggest |
R8667 |
T12782 |
T12783 |
arg1Of |
Sox6,continues |
R8668 |
T12782 |
T12785 |
arg1Of |
Sox6,function |
R8669 |
T12782 |
T12793 |
arg1Of |
Sox6,has |
R867 |
T1761 |
T1758 |
arg2Of |
changes,to |
R8670 |
T12783 |
T12792 |
arg1Of |
continues,and |
R8671 |
T12785 |
T12783 |
arg2Of |
function,continues |
R8672 |
T12785 |
T12784 |
arg1Of |
function,to |
R8673 |
T12785 |
T12787 |
arg1Of |
function,to |
R8674 |
T12787 |
T12786 |
arg1Of |
to,postnatally |
R8675 |
T12791 |
T12787 |
arg2Of |
expression,to |
R8676 |
T12791 |
T12788 |
arg1Of |
expression,silence |
R8677 |
T12791 |
T12789 |
arg1Of |
expression,ɛy |
R8678 |
T12791 |
T12790 |
arg1Of |
expression,globin |
R8679 |
T12792 |
T12780 |
arg2Of |
and,suggest |
R868 |
T1761 |
T1759 |
arg1Of |
changes,local |
R8680 |
T12792 |
T12781 |
arg1Of |
and,that |
R8681 |
T12793 |
T12792 |
arg2Of |
has,and |
R8682 |
T12793 |
T12797 |
arg1Of |
has,in |
R8683 |
T12796 |
T12793 |
arg2Of |
function,has |
R8684 |
T12796 |
T12794 |
arg1Of |
function,a |
R8685 |
T12796 |
T12795 |
arg1Of |
function,unique |
R8686 |
T12799 |
T12797 |
arg2Of |
regulation,in |
R8687 |
T12799 |
T12798 |
arg1Of |
regulation,the |
R8688 |
T12799 |
T12800 |
arg1Of |
regulation,of |
R8689 |
T12801 |
T12800 |
arg2Of |
ɛy-globin,of |
R869 |
T1761 |
T1760 |
arg1Of |
changes,conformational |
R8690 |
T12803 |
T12802 |
arg1Of |
mechanism,The |
R8691 |
T12803 |
T12804 |
arg2Of |
mechanism,by |
R8692 |
T12803 |
T12805 |
arg1Of |
mechanism,which |
R8693 |
T12803 |
T12813 |
arg1Of |
mechanism,remains |
R8694 |
T12803 |
T12815 |
arg1Of |
mechanism,be |
R8695 |
T12803 |
T12816 |
arg2Of |
mechanism,elucidated |
R8696 |
T12806 |
T12807 |
arg1Of |
Sox6,regulates |
R8697 |
T12807 |
T12804 |
arg1Of |
regulates,by |
R8698 |
T12812 |
T12807 |
arg2Of |
genes,regulates |
R8699 |
T12812 |
T12808 |
arg1Of |
genes,the |
R87 |
T295 |
T297 |
arg1Of |
studies,suggested |
R870 |
T1761 |
T1762 |
arg1Of |
changes,[ |
R8700 |
T12812 |
T12809 |
arg1Of |
genes,other |
R8701 |
T12812 |
T12810 |
arg1Of |
genes,embryonic |
R8702 |
T12812 |
T12811 |
arg1Of |
genes,globin |
R8703 |
T12816 |
T12813 |
arg2Of |
elucidated,remains |
R8704 |
T12816 |
T12814 |
arg1Of |
elucidated,to |
R8705 |
T12816 |
T12815 |
arg2Of |
elucidated,be |
R8706 |
T12817 |
T12818 |
arg1Of |
Sox6,has |
R8707 |
T12820 |
T12818 |
arg2Of |
effects,has |
R8708 |
T12820 |
T12819 |
arg1Of |
effects,other |
R8709 |
T12820 |
T12821 |
arg1Of |
effects,in |
R871 |
T1763 |
T1762 |
arg2Of |
"2,3",[ |
R8710 |
T12820 |
T12823 |
arg1Of |
effects,"," |
R8711 |
T12820 |
T12824 |
arg1Of |
effects,including |
R8712 |
T12822 |
T12821 |
arg2Of |
erythropoiesis,in |
R8713 |
T12826 |
T12824 |
arg2Of |
delay,including |
R8714 |
T12826 |
T12825 |
arg1Of |
delay,a |
R8715 |
T12826 |
T12827 |
arg1Of |
delay,in |
R8716 |
T12826 |
T12829 |
arg1Of |
delay,in |
R8717 |
T12828 |
T12827 |
arg2Of |
enucleation/maturation,in |
R8718 |
T12832 |
T12829 |
arg2Of |
mice,in |
R8719 |
T12832 |
T12830 |
arg1Of |
mice,p100H |
R872 |
T1764 |
T1762 |
arg3Of |
],[ |
R8720 |
T12832 |
T12831 |
arg1Of |
mice,mutant |
R8721 |
T12833 |
T12834 |
arg1Of |
This,may |
R8722 |
T12833 |
T12835 |
arg1Of |
This,be |
R8723 |
T12835 |
T12834 |
arg2Of |
be,may |
R8724 |
T12837 |
T12835 |
arg2Of |
result,be |
R8725 |
T12837 |
T12836 |
arg1Of |
result,the |
R8726 |
T12837 |
T12838 |
arg1Of |
result,of |
R8727 |
T12840 |
T12838 |
arg2Of |
effects,of |
R8728 |
T12840 |
T12839 |
arg1Of |
effects,indirect |
R8729 |
T12840 |
T12841 |
arg1Of |
effects,"," |
R873 |
T1770 |
T1767 |
arg1Of |
factors,most |
R8730 |
T12840 |
T12843 |
arg1Of |
effects,as |
R8731 |
T12843 |
T12842 |
arg1Of |
as,such |
R8732 |
T12845 |
T12844 |
arg1Of |
proliferation,stress-induced |
R8733 |
T12845 |
T12846 |
arg1Of |
proliferation,( |
R8734 |
T12845 |
T12852 |
arg1Of |
proliferation,and/or |
R8735 |
T12847 |
T12846 |
arg2Of |
resulting,( |
R8736 |
T12847 |
T12848 |
arg1Of |
resulting,from |
R8737 |
T12850 |
T12848 |
arg2Of |
defects,from |
R8738 |
T12850 |
T12849 |
arg1Of |
defects,cardiac |
R8739 |
T12851 |
T12846 |
arg3Of |
),( |
R874 |
T1770 |
T1768 |
arg1Of |
factors,other |
R8740 |
T12852 |
T12843 |
arg2Of |
and/or,as |
R8741 |
T12853 |
T12852 |
arg2Of |
anemia,and/or |
R8742 |
T12855 |
T12854 |
arg1Of |
anemia,Severe |
R8743 |
T12855 |
T12856 |
arg1Of |
anemia,can |
R8744 |
T12855 |
T12857 |
arg1Of |
anemia,lead |
R8745 |
T12857 |
T12856 |
arg2Of |
lead,can |
R8746 |
T12857 |
T12858 |
arg1Of |
lead,to |
R8747 |
T12860 |
T12859 |
arg1Of |
premature,rapid |
R8748 |
T12861 |
T12858 |
arg2Of |
release,to |
R8749 |
T12861 |
T12860 |
arg1Of |
release,premature |
R875 |
T1770 |
T1769 |
arg1Of |
factors,transcription |
R8750 |
T12861 |
T12862 |
arg1Of |
release,of |
R8751 |
T12861 |
T12865 |
arg1Of |
release,"," |
R8752 |
T12861 |
T12866 |
arg1Of |
release,prior |
R8753 |
T12864 |
T12862 |
arg2Of |
cells,of |
R8754 |
T12864 |
T12863 |
arg1Of |
cells,red |
R8755 |
T12866 |
T12867 |
arg1Of |
prior,to |
R8756 |
T12870 |
T12867 |
arg2Of |
maturation,to |
R8757 |
T12870 |
T12868 |
arg1Of |
maturation,their |
R8758 |
T12870 |
T12869 |
arg1Of |
maturation,complete |
R8759 |
T12874 |
T12873 |
arg1Of |
hematocrit,the |
R876 |
T1770 |
T1771 |
arg1Of |
factors,target |
R8760 |
T12874 |
T12875 |
arg1Of |
hematocrit,of |
R8761 |
T12874 |
T12879 |
arg1Of |
hematocrit,is |
R8762 |
T12874 |
T12883 |
arg1Of |
hematocrit,lower |
R8763 |
T12878 |
T12875 |
arg2Of |
mice,of |
R8764 |
T12878 |
T12876 |
arg1Of |
mice,18.5-dpc |
R8765 |
T12878 |
T12877 |
arg1Of |
mice,mutant |
R8766 |
T12879 |
T12871 |
arg1Of |
is,However |
R8767 |
T12879 |
T12872 |
arg1Of |
is,"," |
R8768 |
T12879 |
T12893 |
arg1Of |
is,and |
R8769 |
T12881 |
T12880 |
arg1Of |
20,only |
R877 |
T1771 |
T1766 |
arg2Of |
target,while |
R8770 |
T12882 |
T12881 |
arg1Of |
%,20 |
R8771 |
T12883 |
T12879 |
arg2Of |
lower,is |
R8772 |
T12883 |
T12882 |
arg1Of |
lower,% |
R8773 |
T12883 |
T12884 |
arg1Of |
lower,than |
R8774 |
T12885 |
T12884 |
arg2Of |
that,than |
R8775 |
T12885 |
T12886 |
arg1Of |
that,of |
R8776 |
T12887 |
T12886 |
arg2Of |
WT,of |
R8777 |
T12887 |
T12888 |
arg1Of |
WT,( |
R8778 |
T12890 |
T12888 |
arg2Of |
data,( |
R8779 |
T12890 |
T12889 |
arg1Of |
data,unpublished |
R878 |
T1771 |
T1777 |
arg1Of |
target,[ |
R8780 |
T12891 |
T12888 |
arg3Of |
),( |
R8781 |
T12893 |
T12892 |
arg1Of |
and,"," |
R8782 |
T12896 |
T12894 |
arg1Of |
anemia,this |
R8783 |
T12896 |
T12895 |
arg1Of |
anemia,mild |
R8784 |
T12896 |
T12897 |
arg1Of |
anemia,is |
R8785 |
T12896 |
T12900 |
arg1Of |
anemia,sufficient |
R8786 |
T12897 |
T12893 |
arg2Of |
is,and |
R8787 |
T12897 |
T12898 |
arg1Of |
is,probably |
R8788 |
T12897 |
T12899 |
arg1Of |
is,not |
R8789 |
T12900 |
T12897 |
arg2Of |
sufficient,is |
R879 |
T1774 |
T1771 |
arg2Of |
groove,target |
R8790 |
T12902 |
T12900 |
arg2Of |
explain,sufficient |
R8791 |
T12902 |
T12901 |
arg1Of |
explain,to |
R8792 |
T12904 |
T12902 |
arg2Of |
extent,explain |
R8793 |
T12904 |
T12903 |
arg1Of |
extent,the |
R8794 |
T12904 |
T12905 |
arg1Of |
extent,of |
R8795 |
T12908 |
T12905 |
arg2Of |
cells,of |
R8796 |
T12908 |
T12906 |
arg1Of |
cells,nucleated |
R8797 |
T12908 |
T12907 |
arg1Of |
cells,red |
R8798 |
T12912 |
T12911 |
arg1Of |
itself,Sox6 |
R8799 |
T12912 |
T12913 |
arg1Of |
itself,may |
R88 |
T297 |
T292 |
arg1Of |
suggested,"," |
R880 |
T1774 |
T1772 |
arg1Of |
groove,the |
R8800 |
T12912 |
T12914 |
arg1Of |
itself,play |
R8801 |
T12914 |
T12909 |
arg1Of |
play,Alternatively |
R8802 |
T12914 |
T12910 |
arg1Of |
play,"," |
R8803 |
T12914 |
T12913 |
arg2Of |
play,may |
R8804 |
T12914 |
T12917 |
arg1Of |
play,in |
R8805 |
T12914 |
T12922 |
arg1Of |
play,"," |
R8806 |
T12914 |
T12923 |
arg1Of |
play,as |
R8807 |
T12916 |
T12914 |
arg2Of |
role,play |
R8808 |
T12916 |
T12915 |
arg1Of |
role,a |
R8809 |
T12921 |
T12917 |
arg2Of |
differentiation,in |
R881 |
T1774 |
T1773 |
arg1Of |
groove,major |
R8810 |
T12921 |
T12918 |
arg1Of |
differentiation,red |
R8811 |
T12921 |
T12919 |
arg1Of |
differentiation,cell |
R8812 |
T12921 |
T12920 |
arg1Of |
differentiation,terminal |
R8813 |
T12924 |
T12925 |
arg1Of |
it,has |
R8814 |
T12924 |
T12926 |
arg1Of |
it,been |
R8815 |
T12924 |
T12927 |
arg2Of |
it,shown |
R8816 |
T12924 |
T12929 |
arg1Of |
it,be |
R8817 |
T12927 |
T12923 |
arg2Of |
shown,as |
R8818 |
T12927 |
T12925 |
arg2Of |
shown,has |
R8819 |
T12927 |
T12926 |
arg2Of |
shown,been |
R882 |
T1774 |
T1775 |
arg1Of |
groove,of |
R8820 |
T12929 |
T12927 |
arg3Of |
be,shown |
R8821 |
T12929 |
T12928 |
arg1Of |
be,to |
R8822 |
T12932 |
T12929 |
arg2Of |
factor,be |
R8823 |
T12932 |
T12930 |
arg1Of |
factor,an |
R8824 |
T12932 |
T12931 |
arg1Of |
factor,important |
R8825 |
T12932 |
T12933 |
arg1Of |
factor,in |
R8826 |
T12934 |
T12935 |
arg1Of |
cardiac,[ |
R8827 |
T12934 |
T12938 |
arg1Of |
cardiac,"," |
R8828 |
T12936 |
T12935 |
arg2Of |
15,[ |
R8829 |
T12937 |
T12935 |
arg3Of |
],[ |
R883 |
T1776 |
T1775 |
arg2Of |
DNA,of |
R8830 |
T12938 |
T12943 |
arg1Of |
",","," |
R8831 |
T12939 |
T12938 |
arg2Of |
neuronal,"," |
R8832 |
T12939 |
T12940 |
arg1Of |
neuronal,[ |
R8833 |
T12941 |
T12940 |
arg2Of |
10,[ |
R8834 |
T12942 |
T12940 |
arg3Of |
],[ |
R8835 |
T12943 |
T12949 |
arg1Of |
",",and |
R8836 |
T12944 |
T12943 |
arg2Of |
astrocytic,"," |
R8837 |
T12944 |
T12945 |
arg1Of |
astrocytic,[ |
R8838 |
T12946 |
T12945 |
arg2Of |
11,[ |
R8839 |
T12947 |
T12945 |
arg3Of |
],[ |
R884 |
T1778 |
T1777 |
arg2Of |
4,[ |
R8840 |
T12949 |
T12933 |
arg2Of |
and,in |
R8841 |
T12949 |
T12948 |
arg1Of |
and,"," |
R8842 |
T12952 |
T12949 |
arg2Of |
programs,and |
R8843 |
T12952 |
T12950 |
arg1Of |
programs,cartilage |
R8844 |
T12952 |
T12951 |
arg1Of |
programs,differentiation |
R8845 |
T12952 |
T12953 |
arg1Of |
programs,[ |
R8846 |
T12954 |
T12953 |
arg2Of |
"32,41–44",[ |
R8847 |
T12955 |
T12953 |
arg3Of |
],[ |
R8848 |
T12957 |
T12956 |
arg1Of |
restoration,The |
R8849 |
T12957 |
T12958 |
arg1Of |
restoration,of |
R885 |
T1779 |
T1777 |
arg3Of |
],[ |
R8850 |
T12957 |
T12964 |
arg1Of |
restoration,in |
R8851 |
T12957 |
T12971 |
arg1Of |
restoration,may |
R8852 |
T12957 |
T12972 |
arg1Of |
restoration,result |
R8853 |
T12960 |
T12958 |
arg2Of |
enucleation,of |
R8854 |
T12960 |
T12959 |
arg1Of |
enucleation,normal |
R8855 |
T12960 |
T12961 |
arg1Of |
enucleation,of |
R8856 |
T12963 |
T12961 |
arg2Of |
cells,of |
R8857 |
T12963 |
T12962 |
arg1Of |
cells,red |
R8858 |
T12966 |
T12964 |
arg2Of |
mouse,in |
R8859 |
T12966 |
T12965 |
arg1Of |
mouse,Sox6-deficient |
R886 |
T1783 |
T1782 |
arg1Of |
proteins,Sox |
R8860 |
T12966 |
T12967 |
arg1Of |
mouse,by |
R8861 |
T12969 |
T12967 |
arg2Of |
day,by |
R8862 |
T12969 |
T12968 |
arg1Of |
day,postnatal |
R8863 |
T12969 |
T12970 |
arg1Of |
day,10.5 |
R8864 |
T12972 |
T12971 |
arg2Of |
result,may |
R8865 |
T12972 |
T12973 |
arg1Of |
result,from |
R8866 |
T12972 |
T12987 |
arg1Of |
result,"," |
R8867 |
T12972 |
T12988 |
arg1Of |
result,since |
R8868 |
T12975 |
T12973 |
arg2Of |
compensation,from |
R8869 |
T12975 |
T12974 |
arg1Of |
compensation,functional |
R887 |
T1783 |
T1784 |
arg1Of |
proteins,may |
R8870 |
T12975 |
T12976 |
arg1Of |
compensation,of |
R8871 |
T12975 |
T12980 |
arg1Of |
compensation,( |
R8872 |
T12979 |
T12976 |
arg2Of |
proteins,of |
R8873 |
T12979 |
T12977 |
arg1Of |
proteins,other |
R8874 |
T12979 |
T12978 |
arg1Of |
proteins,Sox |
R8875 |
T12981 |
T12980 |
arg2Of |
expressed,( |
R8876 |
T12981 |
T12982 |
arg1Of |
expressed,at |
R8877 |
T12985 |
T12982 |
arg2Of |
stages,at |
R8878 |
T12985 |
T12983 |
arg1Of |
stages,later |
R8879 |
T12985 |
T12984 |
arg1Of |
stages,developmental |
R888 |
T1783 |
T1785 |
arg1Of |
proteins,perform |
R8880 |
T12986 |
T12980 |
arg3Of |
),( |
R8881 |
T12990 |
T12989 |
arg1Of |
redundancy,functional |
R8882 |
T12990 |
T12991 |
arg1Of |
redundancy,is |
R8883 |
T12991 |
T12988 |
arg2Of |
is,since |
R8884 |
T12994 |
T12991 |
arg2Of |
theme,is |
R8885 |
T12994 |
T12992 |
arg1Of |
theme,a |
R8886 |
T12994 |
T12993 |
arg1Of |
theme,recurring |
R8887 |
T12994 |
T12995 |
arg1Of |
theme,with |
R8888 |
T12997 |
T12995 |
arg2Of |
proteins,with |
R8889 |
T12997 |
T12996 |
arg1Of |
proteins,Sox |
R889 |
T1783 |
T1794 |
arg1Of |
proteins,organizing |
R8890 |
T12997 |
T12998 |
arg1Of |
proteins,[ |
R8891 |
T12999 |
T12998 |
arg2Of |
"13,45,46",[ |
R8892 |
T13000 |
T12998 |
arg3Of |
],[ |
R8893 |
T13003 |
T13004 |
arg1Of |
erythropoiesis,has |
R8894 |
T13003 |
T13006 |
arg1Of |
erythropoiesis,shifted |
R8895 |
T13006 |
T13001 |
arg1Of |
shifted,Moreover |
R8896 |
T13006 |
T13002 |
arg1Of |
shifted,"," |
R8897 |
T13006 |
T13004 |
arg2Of |
shifted,has |
R8898 |
T13006 |
T13005 |
arg1Of |
shifted,already |
R8899 |
T13006 |
T13007 |
arg1Of |
shifted,from |
R89 |
T297 |
T296 |
arg2Of |
suggested,have |
R890 |
T1785 |
T1780 |
arg1Of |
perform,Therefore |
R8900 |
T13009 |
T13007 |
arg2Of |
liver,from |
R8901 |
T13009 |
T13008 |
arg1Of |
liver,fetal |
R8902 |
T13009 |
T13010 |
arg1Of |
liver,to |
R8903 |
T13012 |
T13010 |
arg2Of |
marrow,to |
R8904 |
T13012 |
T13011 |
arg1Of |
marrow,bone |
R8905 |
T13012 |
T13013 |
arg1Of |
marrow,by |
R8906 |
T13015 |
T13013 |
arg2Of |
day,by |
R8907 |
T13015 |
T13014 |
arg1Of |
day,postnatal |
R8908 |
T13015 |
T13016 |
arg1Of |
day,10.5 |
R8909 |
T13019 |
T13017 |
arg1Of |
change,The |
R891 |
T1785 |
T1781 |
arg1Of |
perform,"," |
R8910 |
T13019 |
T13018 |
arg1Of |
change,accompanying |
R8911 |
T13019 |
T13020 |
arg1Of |
change,in |
R8912 |
T13019 |
T13027 |
arg1Of |
change,may |
R8913 |
T13019 |
T13028 |
arg1Of |
change,permit |
R8914 |
T13022 |
T13020 |
arg2Of |
microenvironment,in |
R8915 |
T13022 |
T13021 |
arg1Of |
microenvironment,the |
R8916 |
T13022 |
T13023 |
arg1Of |
microenvironment,of |
R8917 |
T13026 |
T13023 |
arg2Of |
production,of |
R8918 |
T13026 |
T13024 |
arg1Of |
production,red |
R8919 |
T13026 |
T13025 |
arg1Of |
production,cell |
R892 |
T1785 |
T1784 |
arg2Of |
perform,may |
R8920 |
T13028 |
T13027 |
arg2Of |
permit,may |
R8921 |
T13030 |
T13028 |
arg2Of |
enucleation,permit |
R8922 |
T13030 |
T13029 |
arg1Of |
enucleation,normal |
R8923 |
T13031 |
T13032 |
arg1Of |
Identification,of |
R8924 |
T13031 |
T13041 |
arg1Of |
Identification,will |
R8925 |
T13031 |
T13042 |
arg1Of |
Identification,shed |
R8926 |
T13036 |
T13033 |
arg1Of |
genes,Sox6 |
R8927 |
T13036 |
T13034 |
arg1Of |
genes,downstream |
R8928 |
T13036 |
T13035 |
arg1Of |
genes,target |
R8929 |
T13036 |
T13037 |
arg1Of |
genes,and |
R893 |
T1785 |
T1790 |
arg1Of |
perform,as |
R8930 |
T13037 |
T13032 |
arg2Of |
and,of |
R8931 |
T13040 |
T13037 |
arg2Of |
proteins,and |
R8932 |
T13040 |
T13038 |
arg1Of |
proteins,its |
R8933 |
T13040 |
T13039 |
arg1Of |
proteins,interacting |
R8934 |
T13042 |
T13041 |
arg2Of |
shed,will |
R8935 |
T13042 |
T13044 |
arg1Of |
shed,on |
R8936 |
T13043 |
T13042 |
arg2Of |
light,shed |
R8937 |
T13046 |
T13044 |
arg2Of |
role,on |
R8938 |
T13046 |
T13045 |
arg1Of |
role,the |
R8939 |
T13046 |
T13047 |
arg1Of |
role,of |
R894 |
T1785 |
T1793 |
arg1Of |
perform,by |
R8940 |
T13046 |
T13049 |
arg1Of |
role,in |
R8941 |
T13048 |
T13047 |
arg2Of |
Sox6,of |
R8942 |
T13053 |
T13050 |
arg1Of |
differentiation,red |
R8943 |
T13053 |
T13051 |
arg1Of |
differentiation,cell |
R8944 |
T13053 |
T13052 |
arg1Of |
differentiation,terminal |
R8945 |
T13053 |
T13054 |
arg1Of |
differentiation,and |
R8946 |
T13054 |
T13049 |
arg2Of |
and,in |
R8947 |
T13057 |
T13054 |
arg2Of |
process,and |
R8948 |
T13057 |
T13055 |
arg1Of |
process,the |
R8949 |
T13057 |
T13056 |
arg1Of |
process,enucleation |
R895 |
T1786 |
T1785 |
arg2Of |
part,perform |
R8950 |
T13061 |
T13060 |
arg1Of |
vivo,in |
R8951 |
T13061 |
T13062 |
arg1Of |
vivo,and |
R8952 |
T13064 |
T13062 |
arg2Of |
vitro,and |
R8953 |
T13064 |
T13063 |
arg1Of |
vitro,in |
R8954 |
T13065 |
T13061 |
arg1Of |
analyses,vivo |
R8955 |
T13065 |
T13064 |
arg1Of |
analyses,vitro |
R8956 |
T13065 |
T13066 |
arg1Of |
analyses,suggest |
R8957 |
T13066 |
T13058 |
arg1Of |
suggest,Recently |
R8958 |
T13066 |
T13059 |
arg1Of |
suggest,"," |
R8959 |
T13068 |
T13069 |
arg1Of |
reactivation,of |
R896 |
T1786 |
T1787 |
arg1Of |
part,of |
R8960 |
T13068 |
T13072 |
arg1Of |
reactivation,would |
R8961 |
T13068 |
T13073 |
arg1Of |
reactivation,be |
R8962 |
T13068 |
T13075 |
arg1Of |
reactivation,beneficial |
R8963 |
T13071 |
T13069 |
arg2Of |
ɛ-globin,of |
R8964 |
T13071 |
T13070 |
arg1Of |
ɛ-globin,human |
R8965 |
T13073 |
T13066 |
arg2Of |
be,suggest |
R8966 |
T13073 |
T13067 |
arg1Of |
be,that |
R8967 |
T13073 |
T13072 |
arg2Of |
be,would |
R8968 |
T13073 |
T13082 |
arg1Of |
be,[ |
R8969 |
T13073 |
T13085 |
arg1Of |
be,"," |
R897 |
T1789 |
T1787 |
arg2Of |
function,of |
R8970 |
T13073 |
T13086 |
modOf |
be,providing |
R8971 |
T13075 |
T13073 |
arg2Of |
beneficial,be |
R8972 |
T13075 |
T13074 |
arg1Of |
beneficial,therapeutically |
R8973 |
T13075 |
T13076 |
arg1Of |
beneficial,to |
R8974 |
T13077 |
T13076 |
arg2Of |
adults,to |
R8975 |
T13077 |
T13078 |
arg1Of |
adults,with |
R8976 |
T13081 |
T13078 |
arg2Of |
disease,with |
R8977 |
T13081 |
T13079 |
arg1Of |
disease,sickle |
R8978 |
T13081 |
T13080 |
arg1Of |
disease,cell |
R8979 |
T13083 |
T13082 |
arg2Of |
47,[ |
R898 |
T1789 |
T1788 |
arg1Of |
function,their |
R8980 |
T13084 |
T13082 |
arg3Of |
],[ |
R8981 |
T13088 |
T13086 |
arg2Of |
rationale,providing |
R8982 |
T13088 |
T13087 |
arg1Of |
rationale,a |
R8983 |
T13088 |
T13089 |
arg1Of |
rationale,for |
R8984 |
T13088 |
T13092 |
arg1Of |
rationale,into |
R8985 |
T13091 |
T13089 |
arg2Of |
investigations,for |
R8986 |
T13091 |
T13090 |
arg1Of |
investigations,detailed |
R8987 |
T13095 |
T13092 |
arg2Of |
basis,into |
R8988 |
T13095 |
T13093 |
arg1Of |
basis,the |
R8989 |
T13095 |
T13094 |
arg1Of |
basis,molecular |
R899 |
T1792 |
T1790 |
arg2Of |
proteins,as |
R8990 |
T13095 |
T13096 |
arg1Of |
basis,of |
R8991 |
T13099 |
T13096 |
arg2Of |
silencing,of |
R8992 |
T13099 |
T13097 |
arg1Of |
silencing,ɛ-globin |
R8993 |
T13099 |
T13098 |
arg1Of |
silencing,gene |
R8994 |
T13102 |
T13100 |
arg1Of |
study,The |
R8995 |
T13102 |
T13101 |
arg1Of |
study,present |
R8996 |
T13102 |
T13103 |
arg1Of |
study,identifies |
R8997 |
T13106 |
T13103 |
arg2Of |
repressor,identifies |
R8998 |
T13106 |
T13104 |
arg1Of |
repressor,a |
R8999 |
T13106 |
T13105 |
arg1Of |
repressor,novel |
R90 |
T299 |
T300 |
arg1Of |
Sox6,plays |
R900 |
T1792 |
T1791 |
arg1Of |
proteins,architectural |
R9000 |
T13106 |
T13107 |
arg1Of |
repressor,"," |
R9001 |
T13106 |
T13109 |
arg1Of |
repressor,"," |
R9002 |
T13106 |
T13110 |
arg1Of |
repressor,which |
R9003 |
T13106 |
T13111 |
arg1Of |
repressor,binds |
R9004 |
T13108 |
T13107 |
arg2Of |
Sox6,"," |
R9005 |
T13111 |
T13112 |
arg1Of |
binds,to |
R9006 |
T13111 |
T13117 |
arg1Of |
binds,"," |
R9007 |
T13111 |
T13118 |
arg1Of |
binds,potentially |
R9008 |
T13111 |
T13119 |
arg1Of |
binds,as |
R9009 |
T13116 |
T13112 |
arg2Of |
promoter,to |
R901 |
T1794 |
T1793 |
arg2Of |
organizing,by |
R9010 |
T13116 |
T13113 |
arg1Of |
promoter,the |
R9011 |
T13116 |
T13114 |
arg1Of |
promoter,ɛy |
R9012 |
T13116 |
T13115 |
arg1Of |
promoter,proximal |
R9013 |
T13120 |
T13119 |
arg2Of |
part,as |
R9014 |
T13120 |
T13121 |
arg1Of |
part,of |
R9015 |
T13125 |
T13121 |
arg2Of |
complex,of |
R9016 |
T13125 |
T13122 |
arg1Of |
complex,a |
R9017 |
T13125 |
T13123 |
arg1Of |
complex,larger |
R9018 |
T13125 |
T13124 |
arg1Of |
complex,repression |
R9019 |
T13128 |
T13127 |
arg1Of |
Sox6,murine |
R902 |
T1797 |
T1795 |
arg1Of |
structure,local |
R9020 |
T13128 |
T13129 |
arg1Of |
Sox6,and |
R9021 |
T13129 |
T13133 |
arg1Of |
and,are |
R9022 |
T13129 |
T13136 |
arg1Of |
and,identical |
R9023 |
T13132 |
T13129 |
arg2Of |
counterpart,and |
R9024 |
T13132 |
T13130 |
arg1Of |
counterpart,its |
R9025 |
T13132 |
T13131 |
arg1Of |
counterpart,human |
R9026 |
T13133 |
T13126 |
arg2Of |
are,Because |
R9027 |
T13135 |
T13134 |
arg1Of |
%,94 |
R9028 |
T13136 |
T13133 |
arg2Of |
identical,are |
R9029 |
T13136 |
T13135 |
arg1Of |
identical,% |
R903 |
T1797 |
T1796 |
arg1Of |
structure,chromatin |
R9030 |
T13136 |
T13137 |
arg1Of |
identical,at |
R9031 |
T13141 |
T13137 |
arg2Of |
level,at |
R9032 |
T13141 |
T13138 |
arg1Of |
level,the |
R9033 |
T13141 |
T13139 |
arg1Of |
level,amino |
R9034 |
T13141 |
T13140 |
arg1Of |
level,acid |
R9035 |
T13141 |
T13142 |
arg1Of |
level,[ |
R9036 |
T13143 |
T13142 |
arg2Of |
48,[ |
R9037 |
T13144 |
T13142 |
arg3Of |
],[ |
R9038 |
T13147 |
T13126 |
arg1Of |
is,Because |
R9039 |
T13147 |
T13145 |
arg1Of |
is,"," |
R904 |
T1797 |
T1798 |
arg1Of |
structure,and |
R9040 |
T13148 |
T13147 |
arg2Of |
possible,is |
R9041 |
T13151 |
T13150 |
arg1Of |
Sox6,human |
R9042 |
T13151 |
T13152 |
arg1Of |
Sox6,may |
R9043 |
T13151 |
T13154 |
arg1Of |
Sox6,be |
R9044 |
T13151 |
T13155 |
arg1Of |
Sox6,important |
R9045 |
T13154 |
T13146 |
arg1Of |
be,it |
R9046 |
T13154 |
T13147 |
arg1Of |
be,is |
R9047 |
T13154 |
T13148 |
arg1Of |
be,possible |
R9048 |
T13154 |
T13149 |
arg1Of |
be,that |
R9049 |
T13154 |
T13152 |
arg2Of |
be,may |
R905 |
T1798 |
T1794 |
arg2Of |
and,organizing |
R9050 |
T13154 |
T13153 |
arg1Of |
be,also |
R9051 |
T13154 |
T13156 |
arg1Of |
be,in |
R9052 |
T13155 |
T13154 |
arg2Of |
important,be |
R9053 |
T13160 |
T13156 |
arg2Of |
silencing,in |
R9054 |
T13160 |
T13157 |
arg1Of |
silencing,human |
R9055 |
T13160 |
T13158 |
arg1Of |
silencing,ɛ |
R9056 |
T13160 |
T13159 |
arg1Of |
silencing,globin |
R9057 |
T13161 |
T13162 |
arg1Of |
There,is |
R9058 |
T13162 |
T13175 |
arg1Of |
is,and |
R9059 |
T13165 |
T13162 |
arg2Of |
homology,is |
R906 |
T1798 |
T1804 |
arg1Of |
and,into |
R9060 |
T13165 |
T13163 |
arg1Of |
homology,significant |
R9061 |
T13165 |
T13164 |
arg1Of |
homology,sequence |
R9062 |
T13165 |
T13166 |
arg1Of |
homology,between |
R9063 |
T13173 |
T13166 |
arg2Of |
regions,between |
R9064 |
T13173 |
T13167 |
arg1Of |
regions,the |
R9065 |
T13173 |
T13168 |
arg1Of |
regions,human |
R9066 |
T13173 |
T13169 |
arg1Of |
regions,and |
R9067 |
T13173 |
T13170 |
arg1Of |
regions,mouse |
R9068 |
T13173 |
T13171 |
arg1Of |
regions,ɛ |
R9069 |
T13173 |
T13172 |
arg1Of |
regions,promoter |
R907 |
T1803 |
T1798 |
arg2Of |
factors,and |
R9070 |
T13175 |
T13174 |
arg1Of |
and,"," |
R9071 |
T13178 |
T13176 |
arg1Of |
promoter,the |
R9072 |
T13178 |
T13177 |
arg1Of |
promoter,human |
R9073 |
T13178 |
T13179 |
arg1Of |
promoter,contains |
R9074 |
T13179 |
T13175 |
arg2Of |
contains,and |
R9075 |
T13182 |
T13180 |
arg1Of |
two,at |
R9076 |
T13182 |
T13181 |
arg1Of |
two,least |
R9077 |
T13186 |
T13179 |
arg2Of |
sites,contains |
R9078 |
T13186 |
T13182 |
arg1Of |
sites,two |
R9079 |
T13186 |
T13183 |
arg1Of |
sites,potential |
R908 |
T1803 |
T1799 |
arg1Of |
factors,assembling |
R9080 |
T13186 |
T13184 |
arg1Of |
sites,Sox6 |
R9081 |
T13186 |
T13185 |
arg1Of |
sites,binding |
R9082 |
T13190 |
T13189 |
arg1Of |
existence,the |
R9083 |
T13190 |
T13191 |
arg1Of |
existence,of |
R9084 |
T13190 |
T13200 |
arg1Of |
existence,has |
R9085 |
T13190 |
T13201 |
arg1Of |
existence,been |
R9086 |
T13190 |
T13202 |
arg2Of |
existence,proposed |
R9087 |
T13193 |
T13191 |
arg2Of |
silencer,of |
R9088 |
T13193 |
T13192 |
arg1Of |
silencer,a |
R9089 |
T13193 |
T13194 |
arg1Of |
silencer,of |
R909 |
T1803 |
T1800 |
arg1Of |
factors,other |
R9090 |
T13199 |
T13194 |
arg2Of |
gene,of |
R9091 |
T13199 |
T13195 |
arg1Of |
gene,the |
R9092 |
T13199 |
T13196 |
arg1Of |
gene,human |
R9093 |
T13199 |
T13197 |
arg1Of |
gene,ɛ |
R9094 |
T13199 |
T13198 |
arg1Of |
gene,globin |
R9095 |
T13202 |
T13187 |
arg1Of |
proposed,Indeed |
R9096 |
T13202 |
T13188 |
arg1Of |
proposed,"," |
R9097 |
T13202 |
T13200 |
arg2Of |
proposed,has |
R9098 |
T13202 |
T13201 |
arg2Of |
proposed,been |
R9099 |
T13202 |
T13203 |
arg1Of |
proposed,[ |
R91 |
T300 |
T297 |
arg2Of |
plays,suggested |
R910 |
T1803 |
T1801 |
arg1Of |
factors,DNA-bound |
R9100 |
T13204 |
T13203 |
arg2Of |
"49,50",[ |
R9101 |
T13205 |
T13203 |
arg3Of |
],[ |
R9102 |
T13208 |
T13209 |
arg1Of |
elucidation,of |
R9103 |
T13208 |
T13214 |
arg1Of |
elucidation,and |
R9104 |
T13213 |
T13209 |
arg2Of |
mechanism,of |
R9105 |
T13213 |
T13210 |
arg1Of |
mechanism,the |
R9106 |
T13213 |
T13211 |
arg1Of |
mechanism,Sox6 |
R9107 |
T13213 |
T13212 |
arg1Of |
mechanism,repression |
R9108 |
T13214 |
T13223 |
arg1Of |
and,may |
R9109 |
T13214 |
T13224 |
arg1Of |
and,further |
R911 |
T1803 |
T1802 |
arg1Of |
factors,transcription |
R9110 |
T13214 |
T13233 |
arg1Of |
and,reveal |
R9111 |
T13214 |
T13245 |
arg1Of |
and,β |
R9112 |
T13215 |
T13214 |
arg2Of |
identification,and |
R9113 |
T13215 |
T13216 |
arg1Of |
identification,of |
R9114 |
T13218 |
T13216 |
arg2Of |
components,of |
R9115 |
T13218 |
T13217 |
arg1Of |
components,other |
R9116 |
T13218 |
T13219 |
arg1Of |
components,of |
R9117 |
T13222 |
T13219 |
arg2Of |
complex,of |
R9119 |
T13222 |
T13220 |
arg1Of |
complex,the |
R912 |
T1806 |
T1805 |
arg1Of |
active,biologically |
R9120 |
T13222 |
T13221 |
arg1Of |
complex,Sox6-containing |
R9121 |
T13224 |
T13223 |
arg2Of |
further,may |
R9122 |
T13224 |
T13231 |
arg1Of |
further,and |
R9123 |
T13226 |
T13224 |
arg2Of |
understanding,further |
R9125 |
T13226 |
T13225 |
arg1Of |
understanding,our |
R9126 |
T13226 |
T13227 |
arg1Of |
understanding,of |
R9127 |
T13230 |
T13227 |
arg2Of |
regulation,of |
R9128 |
T13230 |
T13228 |
arg1Of |
regulation,ɛ |
R9129 |
T13230 |
T13229 |
arg1Of |
regulation,globin |
R913 |
T1806 |
T1807 |
arg1Of |
active,"," |
R9130 |
T13231 |
T13206 |
arg1Of |
and,Thus |
R9131 |
T13231 |
T13207 |
arg1Of |
and,"," |
R9132 |
T13233 |
T13244 |
arg1Of |
reveal,and |
R9133 |
T13236 |
T13233 |
arg2Of |
targets,reveal |
R9134 |
T13236 |
T13234 |
arg1Of |
targets,additional |
R9135 |
T13236 |
T13235 |
arg1Of |
targets,molecular |
R9136 |
T13236 |
T13237 |
arg1Of |
targets,for |
R9137 |
T13239 |
T13237 |
arg2Of |
treatment,for |
R9138 |
T13239 |
T13238 |
arg1Of |
treatment,the |
R9139 |
T13239 |
T13240 |
arg1Of |
treatment,of |
R914 |
T1809 |
T1807 |
arg2Of |
defined,"," |
R9140 |
T13243 |
T13240 |
arg2Of |
anemia,of |
R9141 |
T13243 |
T13241 |
arg1Of |
anemia,sickle |
R9142 |
T13243 |
T13242 |
arg1Of |
anemia,cell |
R9143 |
T13244 |
T13231 |
arg2Of |
and,and |
R9144 |
T13244 |
T13232 |
arg1Of |
and,potentially |
R9145 |
T13245 |
T13244 |
arg2Of |
β,and |
R9146 |
T13246 |
T13245 |
arg2Of |
thalassemias,β |
R915 |
T1809 |
T1808 |
arg1Of |
defined,sterically |
R916 |
T1811 |
T1804 |
arg2Of |
complexes,into |
R917 |
T1811 |
T1806 |
arg1Of |
complexes,active |
R918 |
T1811 |
T1809 |
arg1Of |
complexes,defined |
R919 |
T1811 |
T1810 |
arg1Of |
complexes,multiprotein |
R92 |
T300 |
T298 |
arg1Of |
plays,that |
R920 |
T1812 |
T1813 |
arg1Of |
Sox6,has |
R921 |
T1812 |
T1814 |
arg1Of |
Sox6,been |
R922 |
T1812 |
T1815 |
arg2Of |
Sox6,reported |
R923 |
T1812 |
T1817 |
arg1Of |
Sox6,be |
R924 |
T1812 |
T1818 |
arg1Of |
Sox6,able |
R925 |
T1812 |
T1820 |
arg1Of |
Sox6,act |
R926 |
T1815 |
T1813 |
arg2Of |
reported,has |
R927 |
T1815 |
T1814 |
arg2Of |
reported,been |
R928 |
T1817 |
T1815 |
arg3Of |
be,reported |
R929 |
T1817 |
T1816 |
arg1Of |
be,to |
R93 |
T300 |
T303 |
arg1Of |
plays,in |
R930 |
T1818 |
T1817 |
arg2Of |
able,be |
R931 |
T1820 |
T1818 |
arg2Of |
act,able |
R932 |
T1820 |
T1819 |
arg1Of |
act,to |
R933 |
T1820 |
T1821 |
arg1Of |
act,as |
R934 |
T1820 |
T1828 |
arg1Of |
act,"," |
R935 |
T1820 |
T1829 |
arg1Of |
act,depending |
R936 |
T1824 |
T1823 |
arg1Of |
activator,an |
R937 |
T1824 |
T1825 |
arg1Of |
activator,or |
R938 |
T1825 |
T1821 |
arg2Of |
or,as |
R939 |
T1825 |
T1822 |
arg1Of |
or,either |
R94 |
T302 |
T300 |
arg2Of |
role,plays |
R940 |
T1827 |
T1825 |
arg2Of |
repressor,or |
R941 |
T1827 |
T1826 |
arg1Of |
repressor,a |
R942 |
T1830 |
T1829 |
arg2Of |
on,depending |
R943 |
T1832 |
T1831 |
arg1Of |
interactors,its |
R944 |
T1832 |
T1833 |
arg1Of |
interactors,and |
R945 |
T1833 |
T1830 |
arg2Of |
and,on |
R946 |
T1837 |
T1833 |
arg2Of |
context,and |
R947 |
T1837 |
T1834 |
arg1Of |
context,its |
R948 |
T1837 |
T1835 |
arg1Of |
context,target |
R949 |
T1837 |
T1836 |
arg1Of |
context,promoter |
R95 |
T302 |
T301 |
arg1Of |
role,a |
R950 |
T1837 |
T1838 |
arg1Of |
context,[ |
R951 |
T1839 |
T1838 |
arg2Of |
"5,6",[ |
R952 |
T1840 |
T1838 |
arg3Of |
],[ |
R953 |
T1843 |
T1844 |
arg1Of |
Sox6,has |
R954 |
T1843 |
T1846 |
arg1Of |
Sox6,been |
R955 |
T1843 |
T1847 |
arg2Of |
Sox6,shown |
R956 |
T1843 |
T1849 |
arg1Of |
Sox6,act |
R957 |
T1847 |
T1841 |
arg1Of |
shown,Intriguingly |
R958 |
T1847 |
T1842 |
arg1Of |
shown,"," |
R959 |
T1847 |
T1844 |
arg2Of |
shown,has |
R96 |
T305 |
T306 |
arg1Of |
development,of |
R960 |
T1847 |
T1845 |
arg1Of |
shown,also |
R961 |
T1847 |
T1846 |
arg2Of |
shown,been |
R962 |
T1849 |
T1847 |
arg3Of |
act,shown |
R963 |
T1849 |
T1848 |
arg1Of |
act,to |
R964 |
T1849 |
T1850 |
arg1Of |
act,as |
R965 |
T1854 |
T1850 |
arg2Of |
factor,as |
R966 |
T1854 |
T1851 |
arg1Of |
factor,a |
R967 |
T1854 |
T1852 |
arg1Of |
factor,general |
R968 |
T1854 |
T1853 |
arg1Of |
factor,splicing |
R969 |
T1854 |
T1855 |
arg1Of |
factor,that |
R97 |
T305 |
T311 |
arg1Of |
development,"," |
R970 |
T1854 |
T1856 |
arg1Of |
factor,participates |
R971 |
T1856 |
T1857 |
arg1Of |
participates,in |
R972 |
T1859 |
T1857 |
arg2Of |
splicing,in |
R973 |
T1859 |
T1858 |
arg1Of |
splicing,pre-mRNA |
R974 |
T1859 |
T1860 |
arg1Of |
splicing,[ |
R975 |
T1861 |
T1860 |
arg2Of |
7,[ |
R976 |
T1862 |
T1860 |
arg3Of |
],[ |
R977 |
T1863 |
T1864 |
arg1Of |
Depletion,of |
R978 |
T1863 |
T1866 |
arg1Of |
Depletion,in |
R979 |
T1863 |
T1870 |
arg1Of |
Depletion,blocked |
R98 |
T310 |
T306 |
arg2Of |
system,of |
R980 |
T1865 |
T1864 |
arg2Of |
Sox6,of |
R981 |
T1869 |
T1866 |
arg2Of |
extracts,in |
R982 |
T1869 |
T1867 |
arg1Of |
extracts,HeLa |
R983 |
T1869 |
T1868 |
arg1Of |
extracts,cell |
R984 |
T1870 |
T1876 |
arg1Of |
blocked,and |
R985 |
T1871 |
T1870 |
arg2Of |
splicing,blocked |
R986 |
T1871 |
T1872 |
arg1Of |
splicing,of |
R987 |
T1874 |
T1872 |
arg2Of |
substrates,of |
R988 |
T1874 |
T1873 |
arg1Of |
substrates,multiple |
R989 |
T1876 |
T1875 |
arg1Of |
and,"," |
R99 |
T310 |
T307 |
arg1Of |
system,the |
R990 |
T1876 |
T1896 |
modOf |
and,indicating |
R991 |
T1876 |
T1902 |
arg1Of |
and,[ |
R992 |
T1877 |
T1878 |
arg1Of |
expression,of |
R993 |
T1877 |
T1893 |
arg1Of |
expression,restored |
R994 |
T1881 |
T1878 |
arg2Of |
domain,of |
R995 |
T1881 |
T1879 |
arg1Of |
domain,the |
R996 |
T1881 |
T1880 |
arg1Of |
domain,HMG |
R997 |
T1881 |
T1882 |
arg1Of |
domain,of |
R998 |
T1881 |
T1890 |
arg1Of |
domain,in |
R999 |
T1884 |
T1885 |
arg1Of |
Sox6,"," |