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PMC:1310901 / 1798-5127 JSONTXT 17 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1104 13-20 JJ denotes Chronic
T1105 21-28 JJ denotes myeloid
T1106 29-37 NN denotes leukemia
T1107 38-39 -LRB- denotes (
T1108 39-42 NN denotes CML
T1109 42-43 -RRB- denotes )
T1110 44-46 VB denotes is
T1111 47-48 DT denotes a
T1112 49-55 JJ denotes clonal
T1113 56-74 JJ denotes myeloproliferative
T1114 75-83 NN denotes disorder
T1115 84-88 IN denotes with
T1116 89-90 DT denotes a
T1117 91-98 JJ denotes typical
T1118 99-104 CD denotes three
T1119 105-111 JJ denotes phased
T1120 112-118 NN denotes course
T1121 119-120 -LRB- denotes (
T1122 120-127 JJ denotes chronic
T1123 127-128 -COMMA- denotes ,
T1124 129-140 JJ denotes accelerated
T1125 141-144 CC denotes and
T1126 145-152 JJ denotes blastic
T1127 153-158 NN denotes phase
T1128 158-159 -RRB- denotes )
T1129 160-170 VB denotes reflecting
T1130 171-174 DT denotes the
T1131 175-179 NN denotes loss
T1132 180-182 IN denotes of
T1133 183-198 NN denotes differentiation
T1134 199-202 CC denotes and
T1135 203-212 JJ denotes malignant
T1136 213-221 NN denotes progress
T1137 222-227 WDT denotes which
T1138 228-238 RB denotes inevitably
T1139 239-244 VB denotes leads
T1140 245-247 TO denotes to
T1141 248-253 NN denotes death
T1142 254-259 IN denotes after
T1143 260-263 DT denotes the
T1144 264-271 JJ denotes blastic
T1145 272-277 NN denotes phase
T1146 278-279 -LRB- denotes (
T1147 279-282 CD denotes 1,2
T1148 282-283 -RRB- denotes )
T1149 285-288 DT denotes The
T1150 289-297 NN denotes hallmark
T1151 298-305 JJ denotes genetic
T1152 306-316 NN denotes aberration
T1153 317-319 IN denotes of
T1154 320-323 NN denotes CML
T1155 324-326 VB denotes is
T1156 327-328 DT denotes a
T1157 329-339 JJ denotes reciprocal
T1158 340-351 JJ denotes chromosomal
T1159 352-365 NN denotes translocation
T1160 366-367 NN denotes t
T1161 367-368 -LRB- denotes (
T1162 368-369 CD denotes 9
T1163 369-370 -COLON- denotes ;
T1164 370-372 CD denotes 22
T1165 372-373 -RRB- denotes )
T1166 374-381 VB denotes leading
T1167 382-384 TO denotes to
T1168 385-395 NN denotes expression
T1169 396-398 IN denotes of
T1170 399-400 DT denotes a
T1171 401-408 NN denotes bcr-abl
T1172 409-415 NN denotes fusion
T1173 416-420 NN denotes gene
T1174 420-421 -COMMA- denotes ,
T1175 422-424 DT denotes an
T1176 425-433 JJ denotes aberrant
T1177 434-443 VB denotes activated
T1178 444-452 NN denotes tyrosine
T1179 453-459 NN denotes kinase
T1180 460-461 -LRB- denotes (
T1181 461-462 CD denotes 2
T1182 462-463 -RRB- denotes )
T1183 465-474 NN denotes Treatment
T1184 475-479 IN denotes with
T1185 480-490 NN denotes interferon
T1186 491-492 NN denotes α
T1187 493-494 -LRB- denotes (
T1188 494-499 NN denotes IFN-α
T1189 499-500 -RRB- denotes )
T1190 501-509 VB denotes prolongs
T1191 510-518 NN denotes survival
T1192 519-521 IN denotes of
T1193 522-525 NN denotes CML
T1194 526-534 NN denotes patients
T1195 535-538 CC denotes and
T1196 539-541 VB denotes is
T1197 542-552 VB denotes associated
T1198 553-557 IN denotes with
T1199 558-559 DT denotes a
T1200 560-568 JJ denotes complete
T1201 569-580 JJ denotes cytogenetic
T1202 581-589 NN denotes response
T1203 590-592 IN denotes in
T1204 593-597 CD denotes 5–33
T1205 597-598 NN denotes %
T1206 599-601 IN denotes of
T1207 602-605 NN denotes CML
T1208 606-614 NN denotes patients
T1209 615-616 -LRB- denotes (
T1210 616-619 CD denotes 1,2
T1211 619-620 -RRB- denotes )
T1212 622-630 RB denotes Recently
T1213 630-631 -COMMA- denotes ,
T1214 632-634 PRP denotes we
T1215 635-644 VB denotes described
T1216 645-647 DT denotes an
T1217 648-656 JJ denotes impaired
T1218 657-667 NN denotes expression
T1219 668-670 IN denotes of
T1220 671-674 DT denotes the
T1221 675-685 NN denotes interferon
T1222 686-696 JJ denotes regulatory
T1223 697-703 NN denotes factor
T1224 704-705 CD denotes 4
T1225 706-707 -LRB- denotes (
T1226 707-712 NN denotes IRF-4
T1227 712-713 -RRB- denotes )
T1228 714-716 IN denotes in
T1229 717-720 NN denotes CML
T1230 720-721 -COMMA- denotes ,
T1231 722-733 VB denotes correlating
T1232 734-738 IN denotes with
T1233 739-743 JJ denotes poor
T1234 744-752 NN denotes response
T1235 753-755 TO denotes to
T1236 756-761 NN denotes IFN-α
T1237 762-771 NN denotes treatment
T1238 772-773 -LRB- denotes (
T1239 773-774 CD denotes 3
T1240 774-775 -RRB- denotes )
T1241 777-780 DT denotes The
T1242 781-786 NN denotes cause
T1243 787-789 IN denotes of
T1244 790-793 DT denotes the
T1245 794-803 NN denotes silencing
T1246 804-806 IN denotes of
T1247 807-812 NN denotes IRF-4
T1248 813-818 NN denotes level
T1249 819-827 VB denotes remained
T1250 828-835 JJ denotes unclear
T1251 837-847 NN denotes Interferon
T1252 848-858 JJ denotes regulatory
T1253 859-866 NN denotes factors
T1254 867-868 -LRB- denotes (
T1255 868-872 NN denotes IRFs
T1256 872-873 -RRB- denotes )
T1257 874-877 VB denotes are
T1258 878-879 DT denotes a
T1259 880-886 NN denotes family
T1260 887-889 IN denotes of
T1261 890-905 JJ denotes transcriptional
T1262 906-916 NN denotes regulators
T1263 917-924 VB denotes defined
T1264 925-927 IN denotes by
T1265 928-929 DT denotes a
T1266 930-944 JJ denotes characteristic
T1267 945-953 NN denotes homology
T1268 954-956 IN denotes in
T1269 957-962 PRP-DOLLAR- denotes their
T1270 963-974 JJ denotes DNA-binding
T1271 975-981 NN denotes domain
T1272 983-987 PRP denotes They
T1273 988-992 VB denotes play
T1274 993-995 DT denotes an
T1275 996-1005 JJ denotes important
T1276 1006-1010 NN denotes role
T1277 1011-1013 IN denotes in
T1278 1014-1017 DT denotes the
T1279 1018-1028 NN denotes regulation
T1280 1029-1031 IN denotes of
T1281 1032-1039 JJ denotes various
T1282 1040-1045 NN denotes genes
T1283 1046-1047 -LRB- denotes (
T1284 1047-1051 JJ denotes such
T1285 1052-1054 IN denotes as
T1286 1055-1059 NN denotes IFNs
T1287 1059-1060 -COMMA- denotes ,
T1288 1061-1073 NN denotes interleukins
T1289 1073-1074 -COMMA- denotes ,
T1290 1075-1078 NN denotes MHC
T1291 1079-1084 NN denotes class
T1292 1085-1089 NN denotes I/II
T1293 1089-1090 -RRB- denotes )
T1294 1090-1091 -COMMA- denotes ,
T1295 1092-1101 NN denotes apoptosis
T1296 1102-1105 CC denotes and
T1297 1106-1132 NN denotes differentiation/maturation
T1298 1133-1134 -LRB- denotes (
T1299 1134-1137 CD denotes 4–6
T1300 1137-1138 -RRB- denotes )
T1301 1140-1145 NN denotes IRF-4
T1302 1146-1147 -LRB- denotes (
T1303 1147-1167 NN denotes ICSAT/Pip/MUM1/LSIRF
T1304 1167-1168 -RRB- denotes )
T1305 1169-1171 VB denotes is
T1306 1172-1175 CD denotes one
T1307 1176-1182 NN denotes member
T1308 1183-1187 IN denotes with
T1309 1188-1192 RB denotes very
T1310 1193-1203 JJ denotes restricted
T1311 1204-1214 NN denotes expression
T1312 1215-1222 NN denotes pattern
T1313 1222-1223 -COLON- denotes :
T1314 1224-1237 RB denotes Predominately
T1315 1238-1240 NN denotes B-
T1316 1241-1244 CC denotes and
T1317 1245-1254 VB denotes activated
T1318 1255-1268 NN denotes T-lymphocytes
T1319 1269-1272 VB denotes are
T1320 1273-1278 NN denotes IRF-4
T1321 1279-1287 JJ denotes positive
T1322 1288-1289 -LRB- denotes (
T1323 1289-1293 CD denotes 7–11
T1324 1293-1294 -RRB- denotes )
T1325 1296-1298 IN denotes In
T1326 1299-1307 NN denotes contrast
T1327 1308-1310 TO denotes to
T1328 1311-1316 JJ denotes other
T1329 1317-1321 NN denotes IRFs
T1330 1321-1322 -COMMA- denotes ,
T1331 1323-1333 NN denotes expression
T1332 1334-1336 IN denotes of
T1333 1337-1342 NN denotes IRF-4
T1334 1343-1346 MD denotes can
T1335 1346-1349 RB denotes not
T1336 1350-1352 VB denotes be
T1337 1353-1360 VB denotes induced
T1338 1361-1363 IN denotes by
T1339 1364-1368 NN denotes IFNs
T1340 1368-1369 -COMMA- denotes ,
T1341 1370-1373 CC denotes but
T1342 1374-1376 IN denotes by
T1343 1377-1384 NN denotes antigen
T1344 1385-1396 NN denotes stimulation
T1345 1396-1397 -COMMA- denotes ,
T1346 1398-1410 NN denotes crosslinking
T1347 1411-1413 IN denotes of
T1348 1414-1416 NN denotes T-
T1349 1417-1419 CC denotes or
T1350 1420-1426 NN denotes B-cell
T1351 1427-1436 NN denotes receptors
T1352 1437-1439 CC denotes or
T1353 1440-1465 NN denotes phorbol-myristate-acetate
T1354 1466-1467 -LRB- denotes (
T1355 1467-1472 CD denotes 10,11
T1356 1472-1473 -RRB- denotes )
T1357 1475-1485 JJ denotes Consistent
T1358 1486-1490 IN denotes with
T1359 1491-1494 DT denotes the
T1360 1495-1506 NN denotes restriction
T1361 1507-1509 IN denotes of
T1362 1510-1520 NN denotes expression
T1363 1521-1523 TO denotes to
T1364 1524-1539 JJ denotes immunocompetent
T1365 1540-1545 NN denotes cells
T1366 1545-1546 -COMMA- denotes ,
T1367 1547-1551 NN denotes mice
T1368 1552-1556 IN denotes with
T1369 1557-1565 NN denotes deletion
T1370 1566-1568 IN denotes of
T1371 1569-1574 NN denotes IRF-4
T1372 1575-1581 VB denotes failed
T1373 1582-1584 TO denotes to
T1374 1585-1592 VB denotes develop
T1375 1593-1599 JJ denotes mature
T1376 1600-1603 CC denotes and
T1377 1604-1616 RB denotes functionally
T1378 1617-1623 JJ denotes active
T1379 1624-1626 NN denotes B-
T1380 1627-1630 CC denotes and
T1381 1631-1644 NN denotes T-lymphocytes
T1382 1645-1646 -LRB- denotes (
T1383 1646-1648 CD denotes 12
T1384 1648-1649 -RRB- denotes )
T1385 1649-1650 -COMMA- denotes ,
T1386 1651-1654 CC denotes and
T1387 1655-1658 DT denotes the
T1388 1659-1667 JJ denotes impaired
T1389 1668-1678 NN denotes expression
T1390 1679-1681 IN denotes of
T1391 1682-1687 NN denotes IRF-4
T1392 1688-1690 IN denotes in
T1393 1691-1694 NN denotes CML
T1394 1695-1698 VB denotes was
T1395 1699-1712 RB denotes predominately
T1396 1713-1718 VB denotes found
T1397 1719-1721 IN denotes in
T1398 1722-1729 NN denotes T-cells
T1399 1730-1731 -LRB- denotes (
T1400 1731-1732 CD denotes 3
T1401 1732-1733 -RRB- denotes )
T1402 1735-1740 DT denotes These
T1403 1741-1745 NN denotes data
T1404 1746-1753 VB denotes suggest
T1405 1754-1755 DT denotes a
T1406 1756-1763 JJ denotes crucial
T1407 1764-1768 NN denotes role
T1408 1769-1772 IN denotes for
T1409 1773-1778 NN denotes IRF-4
T1410 1779-1781 IN denotes in
T1411 1782-1785 DT denotes the
T1412 1786-1794 NN denotes function
T1413 1795-1797 IN denotes of
T1414 1798-1804 JJ denotes immune
T1415 1805-1810 NN denotes cells
T1416 1812-1823 NN denotes Methylation
T1417 1824-1826 IN denotes of
T1418 1827-1839 NN denotes dinucleotide
T1419 1840-1858 NN denotes cytosine-guanosine
T1420 1859-1865 NN denotes motifs
T1421 1866-1867 -LRB- denotes (
T1422 1867-1870 NN denotes CpG
T1423 1870-1871 -RRB- denotes )
T1424 1871-1872 -COMMA- denotes ,
T1425 1873-1883 RB denotes especially
T1426 1884-1886 IN denotes in
T1427 1887-1890 NN denotes CpG
T1428 1891-1898 NN denotes islands
T1429 1899-1906 VB denotes located
T1430 1907-1909 IN denotes in
T1431 1910-1918 NN denotes promoter
T1432 1919-1926 NN denotes regions
T1433 1926-1927 -COMMA- denotes ,
T1434 1928-1930 VB denotes is
T1435 1931-1934 CD denotes one
T1436 1935-1937 IN denotes of
T1437 1938-1941 DT denotes the
T1438 1942-1952 NN denotes mechanisms
T1439 1953-1955 IN denotes of
T1440 1956-1960 NN denotes gene
T1441 1961-1971 NN denotes regulation
T1442 1972-1974 IN denotes in
T1443 1975-1982 NN denotes mammals
T1444 1983-1986 CC denotes and
T1445 1987-1988 DT denotes a
T1446 1989-1995 JJ denotes common
T1447 1996-2001 NN denotes event
T1448 2002-2004 IN denotes of
T1449 2005-2009 NN denotes gene
T1450 2010-2019 NN denotes silencing
T1451 2020-2022 IN denotes in
T1452 2023-2028 JJ denotes human
T1453 2029-2039 NN denotes neoplasias
T1454 2040-2041 -LRB- denotes (
T1455 2041-2046 CD denotes 13,14
T1456 2046-2047 -RRB- denotes )
T1457 2049-2051 IN denotes As
T1458 2052-2059 VB denotes opposed
T1459 2060-2062 TO denotes to
T1460 2063-2069 JJ denotes normal
T1461 2070-2075 NN denotes cells
T1462 2075-2076 -COMMA- denotes ,
T1463 2077-2093 NN denotes hypermethylation
T1464 2094-2096 IN denotes of
T1465 2097-2100 NN denotes CpG
T1466 2101-2108 NN denotes islands
T1467 2109-2111 VB denotes is
T1468 2112-2113 DT denotes a
T1469 2114-2124 RB denotes frequently
T1470 2125-2133 VB denotes observed
T1471 2134-2144 NN denotes phenomenon
T1472 2145-2147 IN denotes in
T1473 2148-2153 DT denotes every
T1474 2154-2160 NN denotes cancer
T1475 2161-2165 NN denotes type
T1476 2167-2169 FW denotes De
T1477 2170-2174 FW denotes novo
T1478 2175-2178 NN denotes DNA
T1479 2179-2190 NN denotes methylation
T1480 2191-2193 IN denotes of
T1481 2194-2199 NN denotes genes
T1482 2200-2204 JJ denotes such
T1483 2205-2207 IN denotes as
T1484 2208-2212 NN denotes cell
T1485 2213-2218 NN denotes cycle
T1486 2218-2219 -COMMA- denotes ,
T1487 2220-2223 NN denotes DNA
T1488 2224-2230 NN denotes repair
T1489 2230-2231 -COMMA- denotes ,
T1490 2232-2241 NN denotes apoptosis
T1491 2242-2245 CC denotes and
T1492 2246-2251 NN denotes tumor
T1493 2252-2262 NN denotes suppressor
T1494 2263-2268 NN denotes genes
T1495 2269-2271 VB denotes is
T1496 2272-2281 RB denotes therefore
T1497 2282-2289 VB denotes thought
T1498 2290-2292 TO denotes to
T1499 2293-2295 VB denotes be
T1500 2296-2304 VB denotes involved
T1501 2305-2307 IN denotes in
T1502 2308-2321 NN denotes tumorigenesis
T1503 2322-2323 -LRB- denotes (
T1504 2323-2328 CD denotes 15–17
T1505 2328-2329 -RRB- denotes )
T1506 2331-2339 NN denotes Examples
T1507 2340-2343 IN denotes for
T1508 2344-2348 JJ denotes such
T1509 2349-2358 JJ denotes aberrated
T1510 2359-2364 NN denotes genes
T1511 2365-2368 VB denotes are
T1512 2369-2373 NNP denotes MGMT
T1513 2373-2374 -COMMA- denotes ,
T1514 2375-2379 NNP denotes DAPK
T1515 2379-2380 -COMMA- denotes ,
T1516 2381-2387 NN denotes p14ARF
T1517 2387-2388 -COMMA- denotes ,
T1518 2389-2397 NN denotes p15INK4b
T1519 2397-2398 -COMMA- denotes ,
T1520 2399-2407 NN denotes p16INK4a
T1521 2407-2408 -COMMA- denotes ,
T1522 2409-2414 NN denotes BRCA1
T1523 2414-2415 -COMMA- denotes ,
T1524 2416-2421 NN denotes CDH13
T1525 2422-2425 CC denotes and
T1526 2426-2432 NN denotes APAF-1
T1527 2433-2434 -LRB- denotes (
T1528 2434-2439 CD denotes 17–19
T1529 2439-2440 -RRB- denotes )
T1530 2442-2444 IN denotes In
T1531 2445-2448 NN denotes CML
T1532 2448-2449 -COMMA- denotes ,
T1533 2450-2461 NN denotes methylation
T1534 2462-2464 VB denotes is
T1535 2465-2470 VB denotes known
T1536 2471-2473 TO denotes to
T1537 2474-2482 VB denotes regulate
T1538 2483-2493 NN denotes expression
T1539 2494-2496 IN denotes of
T1540 2497-2500 DT denotes the
T1541 2501-2506 NN denotes c-abl
T1542 2506-2507 -COMMA- denotes ,
T1543 2508-2511 DT denotes the
T1544 2512-2515 NN denotes bcr
T1545 2516-2520 NN denotes gene
T1546 2521-2524 CC denotes and
T1547 2525-2531 NN denotes others
T1548 2532-2533 -LRB- denotes (
T1549 2533-2538 CD denotes 20–23
T1550 2538-2539 -RRB- denotes )
T1551 2539-2540 -COMMA- denotes ,
T1552 2541-2544 CC denotes and
T1553 2545-2548 DT denotes the
T1554 2549-2555 NN denotes extent
T1555 2556-2558 IN denotes of
T1556 2559-2570 NN denotes methylation
T1557 2571-2573 IN denotes in
T1558 2574-2577 DT denotes the
T1559 2578-2583 NN denotes c-abl
T1560 2584-2592 NN denotes promoter
T1561 2593-2596 VB denotes has
T1562 2597-2601 VB denotes been
T1563 2602-2607 VB denotes shown
T1564 2608-2610 TO denotes to
T1565 2611-2613 VB denotes be
T1566 2614-2624 VB denotes associated
T1567 2625-2629 IN denotes with
T1568 2630-2638 VB denotes advanced
T1569 2639-2646 NN denotes disease
T1570 2647-2648 -LRB- denotes (
T1571 2648-2650 CD denotes 24
T1572 2650-2651 -RRB- denotes )
T1573 2653-2669 NN denotes Hypermethylation
T1574 2670-2673 IN denotes due
T1575 2674-2676 TO denotes to
T1576 2677-2691 NN denotes overexpression
T1577 2692-2694 IN denotes of
T1578 2695-2698 NN denotes DNA
T1579 2699-2717 NN denotes methyltransferases
T1580 2718-2719 -LRB- denotes (
T1581 2719-2724 NN denotes DNMTs
T1582 2724-2725 -RRB- denotes )
T1583 2726-2733 VB denotes remains
T1584 2734-2737 CD denotes one
T1585 2738-2746 JJ denotes possible
T1586 2747-2758 NN denotes explanation
T1587 2759-2762 IN denotes for
T1588 2763-2765 FW denotes de
T1589 2766-2770 FW denotes novo
T1590 2771-2782 NN denotes methylation
T1591 2783-2785 IN denotes in
T1592 2786-2799 NN denotes tumorigenesis
T1593 2801-2809 RB denotes Recently
T1594 2809-2810 -COMMA- denotes ,
T1595 2811-2816 NN denotes DNMTs
T1596 2817-2821 VB denotes have
T1597 2822-2826 VB denotes been
T1598 2827-2832 VB denotes shown
T1599 2833-2835 TO denotes to
T1600 2836-2838 VB denotes be
T1601 2839-2851 VB denotes up-regulated
T1602 2852-2854 IN denotes in
T1603 2855-2868 JJ denotes hematopoietic
T1604 2869-2881 NN denotes malignancies
T1605 2882-2883 -LRB- denotes (
T1606 2883-2885 CD denotes 25
T1607 2885-2886 -RRB- denotes )
T1608 2888-2906 JJ denotes Methyl-CpG-binding
T1609 2907-2915 NN denotes proteins
T1610 2916-2917 -LRB- denotes (
T1611 2917-2921 NN denotes MBPs
T1612 2921-2922 -RRB- denotes )
T1613 2923-2926 VB denotes are
T1614 2927-2934 VB denotes thought
T1615 2935-2937 TO denotes to
T1616 2938-2945 VB denotes inhibit
T1617 2946-2949 DT denotes the
T1618 2950-2957 NN denotes binding
T1619 2958-2960 IN denotes of
T1620 2961-2976 JJ denotes transcriptional
T1621 2977-2984 NN denotes factors
T1622 2985-2987 TO denotes to
T1623 2988-2991 DT denotes the
T1624 2992-3000 NN denotes promoter
T1625 3001-3004 CC denotes and
T1626 3005-3008 VB denotes are
T1627 3009-3018 RB denotes therefore
T1628 3019-3028 VB denotes discussed
T1629 3029-3031 IN denotes as
T1630 3032-3035 CD denotes one
T1631 3036-3045 NN denotes mechanism
T1632 3046-3048 IN denotes of
T1633 3049-3062 NN denotes transcription
T1634 3063-3073 NN denotes inhibition
T1635 3074-3076 IN denotes by
T1636 3077-3093 NN denotes hypermethylation
T1637 3094-3095 -LRB- denotes (
T1638 3095-3097 CD denotes 26
T1639 3097-3098 -RRB- denotes )
T1640 3100-3102 IN denotes In
T1641 3103-3107 DT denotes this
T1642 3108-3112 NN denotes work
T1643 3112-3113 -COMMA- denotes ,
T1644 3114-3116 PRP denotes we
T1645 3117-3124 VB denotes studied
T1646 3125-3135 NN denotes mechanisms
T1647 3136-3138 IN denotes of
T1648 3139-3144 NN denotes IRF-4
T1649 3145-3149 NN denotes gene
T1650 3150-3160 NN denotes expression
T1651 3161-3170 NN denotes silencing
T1652 3171-3173 IN denotes in
T1653 3174-3182 JJ denotes leukemic
T1654 3183-3188 NN denotes cells
T1655 3190-3192 PRP denotes We
T1656 3193-3201 VB denotes analyzed
T1657 3202-3205 DT denotes the
T1658 3206-3211 NN denotes IRF-4
T1659 3212-3220 NN denotes promoter
T1660 3221-3227 NN denotes region
T1661 3228-3231 IN denotes for
T1662 3232-3239 JJ denotes genetic
T1663 3240-3251 NN denotes aberrations
T1664 3252-3255 CC denotes and
T1665 3256-3269 JJ denotes methylational
T1666 3270-3276 NN denotes status
T1667 3277-3279 IN denotes in
T1668 3280-3294 JJ denotes IRF-4-positive
T1669 3295-3298 CC denotes and
T1670 3299-3308 JJ denotes -negative
T1671 3309-3322 JJ denotes hematopoietic
T1672 3323-3328 NN denotes cells
R1000 T1337 T1334 arg2Of induced,can
R1001 T1337 T1335 arg1Of induced,not
R1002 T1337 T1336 arg2Of induced,be
R1003 T1337 T1341 arg1Of induced,but
R1004 T1337 T1342 arg1Of induced,by
R1005 T1339 T1337 arg1Of IFNs,induced
R1006 T1339 T1338 arg2Of IFNs,by
R1007 T1341 T1340 arg1Of but,","
R1008 T1344 T1343 arg1Of stimulation,antigen
R1009 T1344 T1345 arg1Of stimulation,","
R1010 T1345 T1352 arg1Of ",",or
R1011 T1346 T1345 arg2Of crosslinking,","
R1012 T1346 T1347 arg1Of crosslinking,of
R1013 T1348 T1349 arg1Of T-,or
R1014 T1350 T1349 arg2Of B-cell,or
R1015 T1351 T1347 arg2Of receptors,of
R1016 T1351 T1348 arg1Of receptors,T-
R1017 T1351 T1350 arg1Of receptors,B-cell
R1018 T1352 T1342 arg2Of or,by
R1019 T1353 T1352 arg2Of phorbol-myristate-acetate,or
R1020 T1353 T1354 arg1Of phorbol-myristate-acetate,(
R1021 T1355 T1354 arg2Of "10,11",(
R1022 T1356 T1354 arg3Of ),(
R1023 T1357 T1358 arg1Of Consistent,with
R1024 T1360 T1358 arg2Of restriction,with
R1025 T1360 T1359 arg1Of restriction,the
R1026 T1360 T1361 arg1Of restriction,of
R1027 T1360 T1363 arg1Of restriction,to
R1028 T1362 T1361 arg2Of expression,of
R1029 T1365 T1363 arg2Of cells,to
R1030 T1365 T1364 arg1Of cells,immunocompetent
R1031 T1367 T1368 arg1Of mice,with
R1032 T1367 T1372 arg1Of mice,failed
R1033 T1367 T1374 arg1Of mice,develop
R1034 T1369 T1368 arg2Of deletion,with
R1035 T1369 T1370 arg1Of deletion,of
R1036 T1371 T1370 arg2Of IRF-4,of
R1037 T1372 T1386 arg1Of failed,and
R1038 T1374 T1372 arg2Of develop,failed
R1039 T1374 T1373 arg1Of develop,to
R1040 T1375 T1376 arg1Of mature,and
R1041 T1378 T1376 arg2Of active,and
R1042 T1378 T1377 arg1Of active,functionally
R1043 T1379 T1375 arg1Of B-,mature
R1044 T1379 T1378 arg1Of B-,active
R1045 T1379 T1380 arg1Of B-,and
R1046 T1380 T1374 arg2Of and,develop
R1047 T1381 T1380 arg2Of T-lymphocytes,and
R1048 T1381 T1382 arg1Of T-lymphocytes,(
R1049 T1383 T1382 arg2Of 12,(
R1050 T1384 T1382 arg3Of ),(
R1051 T1386 T1357 arg1Of and,Consistent
R1052 T1386 T1366 arg1Of and,","
R1053 T1386 T1385 arg1Of and,","
R1054 T1389 T1387 arg1Of expression,the
R1055 T1389 T1388 arg1Of expression,impaired
R1056 T1389 T1390 arg1Of expression,of
R1057 T1389 T1392 arg1Of expression,in
R1058 T1389 T1394 arg1Of expression,was
R1059 T1389 T1396 arg2Of expression,found
R1060 T1391 T1390 arg2Of IRF-4,of
R1061 T1393 T1392 arg2Of CML,in
R1062 T1396 T1386 arg2Of found,and
R1063 T1396 T1394 arg2Of found,was
R1064 T1396 T1395 arg1Of found,predominately
R1065 T1396 T1397 arg1Of found,in
R1066 T1398 T1397 arg2Of T-cells,in
R1067 T1398 T1399 arg1Of T-cells,(
R1068 T1400 T1399 arg2Of 3,(
R1069 T1401 T1399 arg3Of ),(
R1070 T1403 T1402 arg1Of data,These
R1071 T1403 T1404 arg1Of data,suggest
R1072 T1407 T1404 arg2Of role,suggest
R1073 T1407 T1405 arg1Of role,a
R1074 T1407 T1406 arg1Of role,crucial
R1075 T1407 T1408 arg1Of role,for
R1076 T1407 T1410 arg1Of role,in
R1077 T1409 T1408 arg2Of IRF-4,for
R1078 T1412 T1410 arg2Of function,in
R1079 T1412 T1411 arg1Of function,the
R1080 T1412 T1413 arg1Of function,of
R1081 T1415 T1413 arg2Of cells,of
R1082 T1415 T1414 arg1Of cells,immune
R1083 T1416 T1417 arg1Of Methylation,of
R1084 T1416 T1424 arg1Of Methylation,","
R1085 T1416 T1426 arg1Of Methylation,in
R1086 T1416 T1434 arg1Of Methylation,is
R1087 T1420 T1417 arg2Of motifs,of
R1088 T1420 T1418 arg1Of motifs,dinucleotide
R1089 T1420 T1419 arg1Of motifs,cytosine-guanosine
R1090 T1420 T1421 arg1Of motifs,(
R1091 T1422 T1421 arg2Of CpG,(
R1092 T1423 T1421 arg3Of ),(
R1093 T1426 T1425 arg1Of in,especially
R1094 T1428 T1426 arg2Of islands,in
R1095 T1428 T1427 arg1Of islands,CpG
R1096 T1428 T1429 arg2Of islands,located
R1097 T1429 T1430 arg1Of located,in
R1098 T1432 T1430 arg2Of regions,in
R1099 T1432 T1431 arg1Of regions,promoter
R1100 T1434 T1433 arg1Of is,","
R1101 T1435 T1436 arg1Of one,of
R1102 T1435 T1444 arg1Of one,and
R1103 T1438 T1436 arg2Of mechanisms,of
R1104 T1438 T1437 arg1Of mechanisms,the
R1105 T1438 T1439 arg1Of mechanisms,of
R1106 T1438 T1442 arg1Of mechanisms,in
R1107 T1441 T1439 arg2Of regulation,of
R1108 T1441 T1440 arg1Of regulation,gene
R1109 T1443 T1442 arg2Of mammals,in
R1110 T1444 T1434 arg2Of and,is
R1111 T1447 T1444 arg2Of event,and
R1112 T1447 T1445 arg1Of event,a
R1113 T1447 T1446 arg1Of event,common
R1114 T1447 T1448 arg1Of event,of
R1115 T1447 T1451 arg1Of event,in
R1116 T1450 T1448 arg2Of silencing,of
R1117 T1450 T1449 arg1Of silencing,gene
R1118 T1453 T1451 arg2Of neoplasias,in
R1119 T1453 T1452 arg1Of neoplasias,human
R1120 T1453 T1454 arg1Of neoplasias,(
R1121 T1455 T1454 arg2Of "13,14",(
R1122 T1456 T1454 arg3Of ),(
R1123 T1458 T1457 arg2Of opposed,As
R1124 T1458 T1459 arg1Of opposed,to
R1125 T1461 T1459 arg2Of cells,to
R1126 T1461 T1460 arg1Of cells,normal
R1127 T1463 T1464 arg1Of hypermethylation,of
R1128 T1463 T1467 arg1Of hypermethylation,is
R1129 T1466 T1464 arg2Of islands,of
R1130 T1466 T1465 arg1Of islands,CpG
R1131 T1467 T1457 arg1Of is,As
R1132 T1467 T1462 arg1Of is,","
R1133 T1467 T1472 arg1Of is,in
R1134 T1470 T1469 arg1Of observed,frequently
R1135 T1471 T1467 arg2Of phenomenon,is
R1136 T1471 T1468 arg1Of phenomenon,a
R1137 T1471 T1470 arg1Of phenomenon,observed
R1138 T1475 T1472 arg2Of type,in
R1139 T1475 T1473 arg1Of type,every
R1140 T1475 T1474 arg1Of type,cancer
R1141 T1477 T1476 arg1Of novo,De
R1142 T1479 T1477 arg1Of methylation,novo
R1143 T1479 T1478 arg1Of methylation,DNA
R1144 T1479 T1480 arg1Of methylation,of
R1145 T1479 T1495 arg1Of methylation,is
R1146 T1479 T1497 arg2Of methylation,thought
R1147 T1479 T1499 arg1Of methylation,be
R1148 T1479 T1500 arg2Of methylation,involved
R1149 T1481 T1480 arg2Of genes,of
R1150 T1481 T1483 arg1Of genes,as
R1151 T1483 T1482 arg1Of as,such
R1152 T1485 T1484 arg1Of cycle,cell
R1153 T1485 T1486 arg1Of cycle,","
R1154 T1486 T1489 arg1Of ",",","
R1155 T1488 T1486 arg2Of repair,","
R1156 T1488 T1487 arg1Of repair,DNA
R1157 T1489 T1491 arg1Of ",",and
R1158 T1490 T1489 arg2Of apoptosis,","
R1159 T1491 T1483 arg2Of and,as
R1160 T1494 T1491 arg2Of genes,and
R1161 T1494 T1492 arg1Of genes,tumor
R1162 T1494 T1493 arg1Of genes,suppressor
R1163 T1497 T1495 arg2Of thought,is
R1164 T1497 T1496 arg1Of thought,therefore
R1165 T1500 T1497 arg3Of involved,thought
R1166 T1500 T1498 arg1Of involved,to
R1167 T1500 T1499 arg2Of involved,be
R1168 T1500 T1501 arg1Of involved,in
R1169 T1502 T1501 arg2Of tumorigenesis,in
R1170 T1502 T1503 arg1Of tumorigenesis,(
R1171 T1504 T1503 arg2Of 15–17,(
R1172 T1505 T1503 arg3Of ),(
R1173 T1506 T1507 arg1Of Examples,for
R1174 T1506 T1511 arg1Of Examples,are
R1175 T1509 T1508 arg1Of aberrated,such
R1176 T1510 T1507 arg2Of genes,for
R1177 T1510 T1509 arg1Of genes,aberrated
R1178 T1512 T1513 arg1Of MGMT,","
R1179 T1513 T1515 arg1Of ",",","
R1180 T1514 T1513 arg2Of DAPK,","
R1181 T1515 T1517 arg1Of ",",","
R1182 T1516 T1515 arg2Of p14ARF,","
R1183 T1517 T1519 arg1Of ",",","
R1184 T1518 T1517 arg2Of p15INK4b,","
R1185 T1519 T1521 arg1Of ",",","
R1186 T1520 T1519 arg2Of p16INK4a,","
R1187 T1521 T1523 arg1Of ",",","
R1188 T1522 T1521 arg2Of BRCA1,","
R1189 T1523 T1525 arg1Of ",",and
R1190 T1524 T1523 arg2Of CDH13,","
R1191 T1525 T1511 arg2Of and,are
R1192 T1526 T1525 arg2Of APAF-1,and
R1193 T1526 T1527 arg1Of APAF-1,(
R1194 T1528 T1527 arg2Of 17–19,(
R1195 T1529 T1527 arg3Of ),(
R1196 T1531 T1530 arg2Of CML,In
R1197 T1533 T1534 arg1Of methylation,is
R1198 T1533 T1535 arg2Of methylation,known
R1199 T1533 T1537 arg1Of methylation,regulate
R1200 T1535 T1534 arg2Of known,is
R1201 T1535 T1552 arg1Of known,and
R1202 T1537 T1535 arg3Of regulate,known
R1203 T1537 T1536 arg1Of regulate,to
R1204 T1538 T1537 arg2Of expression,regulate
R1205 T1538 T1539 arg1Of expression,of
R1206 T1541 T1540 arg1Of c-abl,the
R1207 T1541 T1542 arg1Of c-abl,","
R1208 T1542 T1546 arg1Of ",",and
R1209 T1545 T1542 arg2Of gene,","
R1210 T1545 T1543 arg1Of gene,the
R1211 T1545 T1544 arg1Of gene,bcr
R1212 T1546 T1539 arg2Of and,of
R1213 T1547 T1546 arg2Of others,and
R1214 T1547 T1548 arg1Of others,(
R1215 T1549 T1548 arg2Of 20–23,(
R1216 T1550 T1548 arg3Of ),(
R1217 T1552 T1530 arg1Of and,In
R1218 T1552 T1532 arg1Of and,","
R1219 T1552 T1551 arg1Of and,","
R1220 T1554 T1553 arg1Of extent,the
R1221 T1554 T1555 arg1Of extent,of
R1222 T1554 T1557 arg1Of extent,in
R1223 T1554 T1561 arg1Of extent,has
R1224 T1554 T1562 arg1Of extent,been
R1225 T1554 T1563 arg2Of extent,shown
R1226 T1554 T1565 arg1Of extent,be
R1227 T1554 T1566 arg2Of extent,associated
R1228 T1556 T1555 arg2Of methylation,of
R1229 T1560 T1557 arg2Of promoter,in
R1230 T1560 T1558 arg1Of promoter,the
R1231 T1560 T1559 arg1Of promoter,c-abl
R1232 T1563 T1552 arg2Of shown,and
R1233 T1563 T1561 arg2Of shown,has
R1234 T1563 T1562 arg2Of shown,been
R1235 T1566 T1563 arg3Of associated,shown
R1236 T1566 T1564 arg1Of associated,to
R1237 T1566 T1565 arg2Of associated,be
R1238 T1566 T1567 arg1Of associated,with
R1239 T1569 T1567 arg2Of disease,with
R1240 T1569 T1568 arg2Of disease,advanced
R1241 T1569 T1570 arg1Of disease,(
R1242 T1571 T1570 arg2Of 24,(
R1243 T1572 T1570 arg3Of ),(
R1244 T1573 T1574 arg1Of Hypermethylation,due
R1245 T1573 T1583 arg1Of Hypermethylation,remains
R1246 T1574 T1575 arg1Of due,to
R1247 T1576 T1574 arg2Of overexpression,due
R1248 T1576 T1577 arg1Of overexpression,of
R1249 T1576 T1580 arg1Of overexpression,(
R1250 T1579 T1577 arg2Of methyltransferases,of
R1251 T1579 T1578 arg1Of methyltransferases,DNA
R1252 T1581 T1580 arg2Of DNMTs,(
R1253 T1582 T1580 arg3Of ),(
R1254 T1586 T1583 arg2Of explanation,remains
R1255 T1586 T1584 arg1Of explanation,one
R1256 T1586 T1585 arg1Of explanation,possible
R1257 T1586 T1587 arg1Of explanation,for
R1258 T1589 T1588 arg1Of novo,de
R1259 T1590 T1587 arg2Of methylation,for
R1260 T1590 T1589 arg1Of methylation,novo
R1261 T1590 T1591 arg1Of methylation,in
R1262 T1592 T1591 arg2Of tumorigenesis,in
R1263 T1595 T1596 arg1Of DNMTs,have
R1264 T1595 T1597 arg1Of DNMTs,been
R1265 T1595 T1598 arg2Of DNMTs,shown
R1266 T1595 T1600 arg1Of DNMTs,be
R1267 T1595 T1601 arg2Of DNMTs,up-regulated
R1268 T1598 T1593 arg1Of shown,Recently
R1269 T1598 T1594 arg1Of shown,","
R1270 T1598 T1596 arg2Of shown,have
R1271 T1598 T1597 arg2Of shown,been
R1272 T1601 T1598 arg3Of up-regulated,shown
R1273 T1601 T1599 arg1Of up-regulated,to
R1274 T1601 T1600 arg2Of up-regulated,be
R1275 T1601 T1602 arg1Of up-regulated,in
R1276 T1604 T1602 arg2Of malignancies,in
R1277 T1604 T1603 arg1Of malignancies,hematopoietic
R1278 T1604 T1605 arg1Of malignancies,(
R1279 T1606 T1605 arg2Of 25,(
R1280 T1607 T1605 arg3Of ),(
R1281 T1609 T1608 arg1Of proteins,Methyl-CpG-binding
R1282 T1609 T1610 arg1Of proteins,(
R1283 T1609 T1613 arg1Of proteins,are
R1284 T1609 T1614 arg2Of proteins,thought
R1285 T1609 T1616 arg1Of proteins,inhibit
R1286 T1609 T1626 arg1Of proteins,are
R1287 T1609 T1628 arg2Of proteins,discussed
R1288 T1611 T1610 arg2Of MBPs,(
R1289 T1612 T1610 arg3Of ),(
R1290 T1614 T1613 arg2Of thought,are
R1291 T1614 T1625 arg1Of thought,and
R1292 T1616 T1614 arg3Of inhibit,thought
R1293 T1616 T1615 arg1Of inhibit,to
R1294 T1618 T1616 arg2Of binding,inhibit
R1295 T1618 T1617 arg1Of binding,the
R1296 T1618 T1619 arg1Of binding,of
R1297 T1618 T1622 arg1Of binding,to
R1298 T1621 T1619 arg2Of factors,of
R1299 T1621 T1620 arg1Of factors,transcriptional
R1300 T1624 T1622 arg2Of promoter,to
R1301 T1624 T1623 arg1Of promoter,the
R1302 T1628 T1625 arg2Of discussed,and
R1303 T1628 T1626 arg2Of discussed,are
R1304 T1628 T1627 arg1Of discussed,therefore
R1305 T1628 T1629 arg1Of discussed,as
R1306 T1631 T1629 arg2Of mechanism,as
R1307 T1631 T1630 arg1Of mechanism,one
R1308 T1631 T1632 arg1Of mechanism,of
R1309 T1631 T1635 arg1Of mechanism,by
R1310 T1634 T1632 arg2Of inhibition,of
R1311 T1634 T1633 arg1Of inhibition,transcription
R1312 T1636 T1635 arg2Of hypermethylation,by
R1313 T1636 T1637 arg1Of hypermethylation,(
R1314 T1638 T1637 arg2Of 26,(
R1315 T1639 T1637 arg3Of ),(
R1316 T1642 T1640 arg2Of work,In
R1317 T1642 T1641 arg1Of work,this
R1318 T1644 T1645 arg1Of we,studied
R1319 T1645 T1640 arg1Of studied,In
R1320 T1645 T1643 arg1Of studied,","
R1321 T1645 T1652 arg1Of studied,in
R1322 T1646 T1645 arg2Of mechanisms,studied
R1323 T1646 T1647 arg1Of mechanisms,of
R1324 T1651 T1647 arg2Of silencing,of
R1325 T1651 T1648 arg1Of silencing,IRF-4
R1326 T1651 T1649 arg1Of silencing,gene
R1327 T1651 T1650 arg1Of silencing,expression
R1328 T1654 T1652 arg2Of cells,in
R1329 T1654 T1653 arg1Of cells,leukemic
R1330 T1655 T1656 arg1Of We,analyzed
R1331 T1656 T1661 arg1Of analyzed,for
R1332 T1660 T1656 arg2Of region,analyzed
R1333 T1660 T1657 arg1Of region,the
R1334 T1660 T1658 arg1Of region,IRF-4
R1335 T1660 T1659 arg1Of region,promoter
R1336 T1663 T1662 arg1Of aberrations,genetic
R1337 T1663 T1664 arg1Of aberrations,and
R1338 T1664 T1661 arg2Of and,for
R1339 T1664 T1667 arg1Of and,in
R1340 T1666 T1664 arg2Of status,and
R1341 T1666 T1665 arg1Of status,methylational
R1342 T1668 T1669 arg1Of IRF-4-positive,and
R1343 T1670 T1669 arg2Of -negative,and
R1344 T1672 T1667 arg2Of cells,in
R1345 T1672 T1668 arg1Of cells,IRF-4-positive
R1346 T1672 T1670 arg1Of cells,-negative
R1347 T1672 T1671 arg1Of cells,hematopoietic
R772 T1106 T1104 arg1Of leukemia,Chronic
R773 T1106 T1105 arg1Of leukemia,myeloid
R774 T1106 T1107 arg1Of leukemia,(
R775 T1106 T1110 arg1Of leukemia,is
R776 T1108 T1107 arg2Of CML,(
R777 T1109 T1107 arg3Of ),(
R778 T1114 T1110 arg2Of disorder,is
R779 T1114 T1111 arg1Of disorder,a
R780 T1114 T1112 arg1Of disorder,clonal
R781 T1114 T1113 arg1Of disorder,myeloproliferative
R782 T1114 T1115 arg1Of disorder,with
R783 T1120 T1115 arg2Of course,with
R784 T1120 T1116 arg1Of course,a
R785 T1120 T1117 arg1Of course,typical
R786 T1120 T1118 arg1Of course,three
R787 T1120 T1119 arg1Of course,phased
R788 T1120 T1121 arg1Of course,(
R789 T1120 T1129 arg1Of course,reflecting
R790 T1122 T1123 arg1Of chronic,","
R791 T1123 T1125 arg1Of ",",and
R792 T1124 T1123 arg2Of accelerated,","
R793 T1126 T1125 arg2Of blastic,and
R794 T1127 T1121 arg2Of phase,(
R795 T1127 T1122 arg1Of phase,chronic
R796 T1127 T1124 arg1Of phase,accelerated
R797 T1127 T1126 arg1Of phase,blastic
R798 T1128 T1121 arg3Of ),(
R799 T1131 T1129 arg2Of loss,reflecting
R800 T1131 T1130 arg1Of loss,the
R801 T1131 T1132 arg1Of loss,of
R802 T1131 T1137 arg1Of loss,which
R803 T1131 T1139 arg1Of loss,leads
R804 T1133 T1134 arg1Of differentiation,and
R805 T1134 T1132 arg2Of and,of
R806 T1136 T1134 arg2Of progress,and
R807 T1136 T1135 arg1Of progress,malignant
R808 T1139 T1138 arg1Of leads,inevitably
R809 T1139 T1140 arg1Of leads,to
R810 T1139 T1142 arg1Of leads,after
R811 T1141 T1140 arg2Of death,to
R812 T1145 T1142 arg2Of phase,after
R813 T1145 T1143 arg1Of phase,the
R814 T1145 T1144 arg1Of phase,blastic
R815 T1145 T1146 arg1Of phase,(
R816 T1147 T1146 arg2Of "1,2",(
R817 T1148 T1146 arg3Of ),(
R818 T1152 T1149 arg1Of aberration,The
R819 T1152 T1150 arg1Of aberration,hallmark
R820 T1152 T1151 arg1Of aberration,genetic
R821 T1152 T1153 arg1Of aberration,of
R822 T1152 T1155 arg1Of aberration,is
R823 T1154 T1153 arg2Of CML,of
R824 T1160 T1155 arg2Of t,is
R825 T1160 T1156 arg1Of t,a
R826 T1160 T1157 arg1Of t,reciprocal
R827 T1160 T1158 arg1Of t,chromosomal
R828 T1160 T1159 arg1Of t,translocation
R829 T1160 T1161 arg1Of t,(
R830 T1160 T1166 arg1Of t,leading
R831 T1162 T1163 arg1Of 9,;
R832 T1163 T1161 arg2Of ;,(
R833 T1164 T1163 arg2Of 22,;
R834 T1165 T1161 arg3Of ),(
R835 T1166 T1167 arg1Of leading,to
R836 T1168 T1167 arg2Of expression,to
R837 T1168 T1169 arg1Of expression,of
R838 T1173 T1169 arg2Of gene,of
R839 T1173 T1170 arg1Of gene,a
R840 T1173 T1171 arg1Of gene,bcr-abl
R841 T1173 T1172 arg1Of gene,fusion
R842 T1173 T1174 arg1Of gene,","
R843 T1179 T1174 arg2Of kinase,","
R844 T1179 T1175 arg1Of kinase,an
R845 T1179 T1176 arg1Of kinase,aberrant
R846 T1179 T1177 arg2Of kinase,activated
R847 T1179 T1178 arg1Of kinase,tyrosine
R848 T1179 T1180 arg1Of kinase,(
R849 T1181 T1180 arg2Of 2,(
R850 T1182 T1180 arg3Of ),(
R851 T1183 T1184 arg1Of Treatment,with
R852 T1183 T1190 arg1Of Treatment,prolongs
R853 T1183 T1196 arg1Of Treatment,is
R854 T1183 T1197 arg2Of Treatment,associated
R855 T1186 T1184 arg2Of α,with
R856 T1186 T1185 arg1Of α,interferon
R857 T1186 T1187 arg1Of α,(
R858 T1188 T1187 arg2Of IFN-α,(
R859 T1189 T1187 arg3Of ),(
R860 T1190 T1195 arg1Of prolongs,and
R861 T1191 T1190 arg2Of survival,prolongs
R862 T1191 T1192 arg1Of survival,of
R863 T1194 T1192 arg2Of patients,of
R864 T1194 T1193 arg1Of patients,CML
R865 T1197 T1195 arg2Of associated,and
R866 T1197 T1196 arg2Of associated,is
R867 T1197 T1198 arg1Of associated,with
R868 T1202 T1198 arg2Of response,with
R869 T1202 T1199 arg1Of response,a
R870 T1202 T1200 arg1Of response,complete
R871 T1202 T1201 arg1Of response,cytogenetic
R872 T1202 T1203 arg1Of response,in
R873 T1205 T1203 arg2Of %,in
R874 T1205 T1204 arg1Of %,5–33
R875 T1205 T1206 arg1Of %,of
R876 T1208 T1206 arg2Of patients,of
R877 T1208 T1207 arg1Of patients,CML
R878 T1208 T1209 arg1Of patients,(
R879 T1210 T1209 arg2Of "1,2",(
R880 T1211 T1209 arg3Of ),(
R881 T1214 T1215 arg1Of we,described
R882 T1215 T1212 arg1Of described,Recently
R883 T1215 T1213 arg1Of described,","
R884 T1215 T1228 arg1Of described,in
R885 T1215 T1230 arg1Of described,","
R886 T1215 T1231 modOf described,correlating
R887 T1218 T1215 arg2Of expression,described
R888 T1218 T1216 arg1Of expression,an
R889 T1218 T1217 arg1Of expression,impaired
R890 T1218 T1219 arg1Of expression,of
R891 T1223 T1219 arg2Of factor,of
R892 T1223 T1220 arg1Of factor,the
R893 T1223 T1221 arg1Of factor,interferon
R894 T1223 T1222 arg1Of factor,regulatory
R895 T1223 T1224 arg1Of factor,4
R896 T1223 T1225 arg1Of factor,(
R897 T1226 T1225 arg2Of IRF-4,(
R898 T1227 T1225 arg3Of ),(
R899 T1229 T1228 arg2Of CML,in
R900 T1231 T1232 arg1Of correlating,with
R901 T1234 T1232 arg2Of response,with
R902 T1234 T1233 arg1Of response,poor
R903 T1234 T1235 arg1Of response,to
R904 T1237 T1235 arg2Of treatment,to
R905 T1237 T1236 arg1Of treatment,IFN-α
R906 T1237 T1238 arg1Of treatment,(
R907 T1239 T1238 arg2Of 3,(
R908 T1240 T1238 arg3Of ),(
R909 T1242 T1241 arg1Of cause,The
R910 T1242 T1243 arg1Of cause,of
R911 T1242 T1249 arg1Of cause,remained
R912 T1242 T1250 arg1Of cause,unclear
R913 T1245 T1243 arg2Of silencing,of
R914 T1245 T1244 arg1Of silencing,the
R915 T1245 T1246 arg1Of silencing,of
R916 T1248 T1246 arg2Of level,of
R917 T1248 T1247 arg1Of level,IRF-4
R918 T1250 T1249 arg2Of unclear,remained
R919 T1253 T1251 arg1Of factors,Interferon
R920 T1253 T1252 arg1Of factors,regulatory
R921 T1253 T1254 arg1Of factors,(
R922 T1253 T1257 arg1Of factors,are
R923 T1255 T1254 arg2Of IRFs,(
R924 T1256 T1254 arg3Of ),(
R925 T1259 T1257 arg2Of family,are
R926 T1259 T1258 arg1Of family,a
R927 T1259 T1260 arg1Of family,of
R928 T1262 T1260 arg2Of regulators,of
R929 T1262 T1261 arg1Of regulators,transcriptional
R930 T1262 T1263 arg2Of regulators,defined
R931 T1267 T1263 arg1Of homology,defined
R932 T1267 T1264 arg2Of homology,by
R933 T1267 T1265 arg1Of homology,a
R934 T1267 T1266 arg1Of homology,characteristic
R935 T1267 T1268 arg1Of homology,in
R936 T1271 T1268 arg2Of domain,in
R937 T1271 T1269 arg1Of domain,their
R938 T1271 T1270 arg1Of domain,DNA-binding
R939 T1272 T1273 arg1Of They,play
R940 T1273 T1277 arg1Of play,in
R941 T1276 T1273 arg2Of role,play
R942 T1276 T1274 arg1Of role,an
R943 T1276 T1275 arg1Of role,important
R944 T1279 T1280 arg1Of regulation,of
R945 T1279 T1294 arg1Of regulation,","
R946 T1282 T1280 arg2Of genes,of
R947 T1282 T1281 arg1Of genes,various
R948 T1282 T1283 arg1Of genes,(
R949 T1282 T1285 arg1Of genes,as
R950 T1285 T1284 arg1Of as,such
R951 T1286 T1287 arg1Of IFNs,","
R952 T1287 T1289 arg1Of ",",","
R953 T1288 T1287 arg2Of interleukins,","
R954 T1289 T1285 arg2Of ",",as
R955 T1292 T1289 arg2Of I/II,","
R956 T1292 T1290 arg1Of I/II,MHC
R957 T1292 T1291 arg1Of I/II,class
R958 T1292 T1293 arg1Of I/II,)
R959 T1294 T1277 arg2Of ",",in
R960 T1294 T1278 arg1Of ",",the
R961 T1295 T1296 arg1Of apoptosis,and
R962 T1296 T1294 arg2Of and,","
R963 T1296 T1298 arg1Of and,(
R964 T1297 T1296 arg2Of differentiation/maturation,and
R965 T1299 T1298 arg2Of 4–6,(
R966 T1300 T1298 arg3Of ),(
R967 T1301 T1302 arg1Of IRF-4,(
R968 T1301 T1305 arg1Of IRF-4,is
R969 T1303 T1302 arg2Of ICSAT/Pip/MUM1/LSIRF,(
R970 T1304 T1302 arg3Of ),(
R971 T1307 T1305 arg2Of member,is
R972 T1307 T1306 arg1Of member,one
R973 T1307 T1308 arg1Of member,with
R974 T1307 T1313 arg1Of member,:
R975 T1310 T1309 arg1Of restricted,very
R976 T1312 T1308 arg2Of pattern,with
R977 T1312 T1310 arg1Of pattern,restricted
R978 T1312 T1311 arg1Of pattern,expression
R979 T1315 T1314 arg1Of B-,Predominately
R980 T1315 T1316 arg1Of B-,and
R981 T1316 T1319 arg1Of and,are
R982 T1318 T1316 arg2Of T-lymphocytes,and
R983 T1318 T1317 arg2Of T-lymphocytes,activated
R984 T1320 T1319 arg2Of IRF-4,are
R985 T1320 T1321 arg1Of IRF-4,positive
R986 T1320 T1322 arg1Of IRF-4,(
R987 T1323 T1322 arg2Of 7–11,(
R988 T1324 T1322 arg3Of ),(
R989 T1326 T1325 arg2Of contrast,In
R990 T1326 T1327 arg1Of contrast,to
R991 T1329 T1327 arg2Of IRFs,to
R992 T1329 T1328 arg1Of IRFs,other
R993 T1331 T1332 arg1Of expression,of
R994 T1331 T1334 arg1Of expression,can
R995 T1331 T1336 arg1Of expression,be
R996 T1331 T1337 arg2Of expression,induced
R997 T1333 T1332 arg2Of IRF-4,of
R998 T1337 T1325 arg1Of induced,In
R999 T1337 T1330 arg1Of induced,","