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PMC:1134658 JSONTXT 20 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T191 0-5 NN denotes BMP-6
T192 6-14 VB denotes inhibits
T193 15-21 NN denotes growth
T194 22-24 IN denotes of
T195 25-31 JJ denotes mature
T196 32-37 JJ denotes human
T197 38-39 NN denotes B
T198 40-45 NN denotes cells
T199 45-46 -COLON- denotes ;
T200 47-56 NN denotes induction
T201 57-59 IN denotes of
T202 60-64 NN denotes Smad
T203 65-80 NN denotes phosphorylation
T204 81-84 CC denotes and
T205 85-97 NN denotes upregulation
T206 98-100 IN denotes of
T207 101-104 NN denotes Id1
T208 116-126 NN denotes Background
T209 127-131 NN denotes Bone
T210 132-145 JJ denotes morphogenetic
T211 146-154 NN denotes proteins
T212 155-156 -LRB- denotes (
T213 156-160 NN denotes BMPs
T214 160-161 -RRB- denotes )
T215 162-168 VB denotes belong
T216 169-171 TO denotes to
T217 172-175 DT denotes the
T218 176-181 NN denotes TGF-β
T219 182-193 NN denotes superfamily
T220 194-197 CC denotes and
T221 198-201 VB denotes are
T222 202-210 VB denotes secreted
T223 211-219 NN denotes proteins
T224 220-224 IN denotes with
T225 225-236 JJ denotes pleiotropic
T226 237-242 NN denotes roles
T227 243-245 IN denotes in
T228 246-250 JJ denotes many
T229 251-260 JJ denotes different
T230 261-265 NN denotes cell
T231 266-271 NN denotes types
T232 273-274 DT denotes A
T233 275-284 JJ denotes potential
T234 285-289 NN denotes role
T235 290-292 IN denotes of
T236 293-298 NN denotes BMP-6
T237 299-301 IN denotes in
T238 302-305 DT denotes the
T239 306-312 JJ denotes immune
T240 313-319 NN denotes system
T241 320-323 VB denotes has
T242 324-328 VB denotes been
T243 329-336 VB denotes implied
T244 337-339 IN denotes by
T245 340-347 JJ denotes various
T246 348-355 NN denotes studies
T247 356-358 IN denotes of
T248 359-368 JJ denotes malignant
T249 369-372 CC denotes and
T250 373-383 JJ denotes rheumatoid
T251 384-392 NN denotes diseases
T252 394-396 IN denotes In
T253 397-400 DT denotes the
T254 401-408 JJ denotes present
T255 409-414 NN denotes study
T256 414-415 -COMMA- denotes ,
T257 416-418 PRP denotes we
T258 419-427 VB denotes explored
T259 428-431 DT denotes the
T260 432-436 NN denotes role
T261 437-439 IN denotes of
T262 440-445 NN denotes BMP-6
T263 446-448 IN denotes in
T264 449-455 JJ denotes normal
T265 456-461 JJ denotes human
T266 462-472 JJ denotes peripheral
T267 473-478 NN denotes blood
T268 479-480 NN denotes B
T269 481-486 NN denotes cells
T270 489-496 NN denotes Results
T271 497-500 DT denotes The
T272 501-502 NN denotes B
T273 503-508 NN denotes cells
T274 509-513 VB denotes were
T275 514-519 VB denotes found
T276 520-522 TO denotes to
T277 523-530 VB denotes express
T278 531-534 NN denotes BMP
T279 535-539 NN denotes type
T280 540-541 CD denotes I
T281 542-545 CC denotes and
T282 546-550 NN denotes type
T283 551-553 CD denotes II
T284 554-563 NN denotes receptors
T285 564-567 CC denotes and
T286 568-573 NN denotes BMP-6
T287 574-581 RB denotes rapidly
T288 582-589 VB denotes induced
T289 590-605 NN denotes phosphorylation
T290 606-608 IN denotes of
T291 609-618 NN denotes Smad1/5/8
T292 620-631 RB denotes Furthermore
T293 631-632 -COMMA- denotes ,
T294 633-653 NN denotes Smad-phosphorylation
T295 654-657 VB denotes was
T296 658-666 VB denotes followed
T297 667-669 IN denotes by
T298 670-682 NN denotes upregulation
T299 683-685 IN denotes of
T300 686-689 NN denotes Id1
T301 690-694 NN denotes mRNA
T302 695-698 CC denotes and
T303 699-702 NN denotes Id1
T304 703-710 NN denotes protein
T305 710-711 -COMMA- denotes ,
T306 712-719 IN denotes whereas
T307 720-723 NN denotes Id2
T308 724-727 CC denotes and
T309 728-731 NN denotes Id3
T310 732-742 NN denotes expression
T311 743-746 VB denotes was
T312 747-750 RB denotes not
T313 751-759 VB denotes affected
T314 761-772 RB denotes Furthermore
T315 772-773 -COMMA- denotes ,
T316 774-776 PRP denotes we
T317 777-782 VB denotes found
T318 783-787 IN denotes that
T319 788-793 NN denotes BMP-6
T320 794-797 VB denotes had
T321 798-800 DT denotes an
T322 801-818 JJ denotes antiproliferative
T323 819-825 NN denotes effect
T324 826-830 CC denotes both
T325 831-833 IN denotes in
T326 834-839 NN denotes naïve
T327 840-841 -LRB- denotes (
T328 841-851 NN denotes CD19+CD27-
T329 851-852 -RRB- denotes )
T330 853-856 CC denotes and
T331 857-863 NN denotes memory
T332 864-865 NN denotes B
T333 866-871 NN denotes cells
T334 872-873 -LRB- denotes (
T335 873-883 JJ denotes CD19+CD27+
T336 883-884 -RRB- denotes )
T337 885-895 VB denotes stimulated
T338 896-900 IN denotes with
T339 901-909 NN denotes anti-IgM
T340 910-915 RB denotes alone
T341 916-918 CC denotes or
T342 919-922 DT denotes the
T343 923-931 VB denotes combined
T344 932-938 NN denotes action
T345 939-941 IN denotes of
T346 942-950 JJ denotes anti-IgM
T347 951-954 CC denotes and
T348 955-960 NN denotes CD40L
T349 962-974 RB denotes Additionally
T350 974-975 -COMMA- denotes ,
T351 976-981 NN denotes BMP-6
T352 982-989 VB denotes induced
T353 990-994 NN denotes cell
T354 995-1000 NN denotes death
T355 1001-1003 IN denotes in
T356 1004-1013 VB denotes activated
T357 1014-1020 NN denotes memory
T358 1021-1022 NN denotes B
T359 1023-1028 NN denotes cells
T360 1030-1041 RB denotes Importantly
T361 1041-1042 -COMMA- denotes ,
T362 1043-1046 DT denotes the
T363 1047-1064 JJ denotes antiproliferative
T364 1065-1071 NN denotes effect
T365 1072-1074 IN denotes of
T366 1075-1080 NN denotes BMP-6
T367 1081-1083 IN denotes in
T368 1084-1091 NN denotes B-cells
T369 1092-1095 VB denotes was
T370 1096-1106 RB denotes completely
T371 1107-1118 VB denotes neutralized
T372 1119-1121 IN denotes by
T373 1122-1125 DT denotes the
T374 1126-1133 JJ denotes natural
T375 1134-1144 NN denotes antagonist
T376 1144-1145 -COMMA- denotes ,
T377 1146-1152 NN denotes noggin
T378 1154-1165 RB denotes Furthermore
T379 1165-1166 -COMMA- denotes ,
T380 1167-1168 NN denotes B
T381 1169-1174 NN denotes cells
T382 1175-1179 VB denotes were
T383 1180-1192 VB denotes demonstrated
T384 1193-1195 TO denotes to
T385 1196-1206 VB denotes upregulate
T386 1207-1212 NN denotes BMP-6
T387 1213-1217 NN denotes mRNA
T388 1218-1222 IN denotes upon
T389 1223-1234 NN denotes stimulation
T390 1235-1239 IN denotes with
T391 1240-1248 NN denotes anti-IgM
T392 1251-1261 NN denotes Conclusion
T393 1262-1264 IN denotes In
T394 1265-1271 JJ denotes mature
T395 1272-1277 JJ denotes human
T396 1278-1279 NN denotes B
T397 1280-1285 NN denotes cells
T398 1285-1286 -COMMA- denotes ,
T399 1287-1292 NN denotes BMP-6
T400 1293-1302 VB denotes inhibited
T401 1303-1307 NN denotes cell
T402 1308-1314 NN denotes growth
T403 1314-1315 -COMMA- denotes ,
T404 1316-1319 CC denotes and
T405 1320-1327 RB denotes rapidly
T406 1328-1335 VB denotes induced
T407 1336-1351 NN denotes phosphorylation
T408 1352-1354 IN denotes of
T409 1355-1364 NN denotes Smad1/5/8
T410 1365-1373 VB denotes followed
T411 1374-1376 IN denotes by
T412 1377-1379 DT denotes an
T413 1380-1392 NN denotes upregulation
T414 1393-1395 IN denotes of
T415 1396-1399 NN denotes Id1
T1148 1414-1421 NN denotes Members
T1149 1422-1424 IN denotes of
T1150 1425-1428 DT denotes the
T1151 1429-1441 VB denotes transforming
T1152 1442-1448 NN denotes growth
T1153 1449-1455 NN denotes factor
T1154 1456-1457 NN denotes β
T1155 1458-1459 -LRB- denotes (
T1156 1459-1464 NN denotes TGF-β
T1157 1464-1465 -RRB- denotes )
T1158 1466-1477 NN denotes superfamily
T1159 1478-1482 VB denotes play
T1160 1483-1490 JJ denotes central
T1161 1491-1496 NN denotes roles
T1162 1497-1499 IN denotes in
T1163 1500-1511 VB denotes controlling
T1164 1512-1520 JJ denotes cellular
T1165 1521-1534 NN denotes proliferation
T1166 1534-1535 -COMMA- denotes ,
T1167 1536-1551 NN denotes differentiation
T1168 1551-1552 -COMMA- denotes ,
T1169 1553-1562 NN denotes migration
T1170 1563-1566 CC denotes and
T1171 1567-1576 NN denotes apoptosis
T1172 1577-1578 -LRB- denotes [
T1173 1578-1579 CD denotes 1
T1174 1579-1580 -RRB- denotes ]
T1175 1582-1587 DT denotes These
T1176 1588-1597 NN denotes cytokines
T1177 1598-1601 MD denotes can
T1178 1602-1604 VB denotes be
T1179 1605-1612 VB denotes divided
T1180 1613-1617 IN denotes into
T1181 1618-1623 CD denotes three
T1182 1624-1633 NN denotes subgroups
T1183 1633-1634 -COLON- denotes :
T1184 1635-1640 NN denotes TGF-β
T1185 1640-1641 -COMMA- denotes ,
T1186 1642-1645 DT denotes the
T1187 1646-1663 NN denotes activins/inhibins
T1188 1663-1664 -COMMA- denotes ,
T1189 1665-1668 CC denotes and
T1190 1669-1672 DT denotes the
T1191 1673-1677 NN denotes bone
T1192 1678-1691 JJ denotes morphogenetic
T1193 1692-1700 NN denotes proteins
T1194 1701-1702 -LRB- denotes (
T1195 1702-1706 NN denotes BMPs
T1196 1706-1707 -RRB- denotes )
T1197 1707-1708 -COMMA- denotes ,
T1198 1709-1711 IN denotes of
T1199 1712-1717 WDT denotes which
T1200 1718-1721 DT denotes the
T1201 1722-1728 JJ denotes latter
T1202 1729-1739 NN denotes constitute
T1203 1740-1743 DT denotes the
T1204 1744-1751 JJ denotes largest
T1205 1752-1758 NN denotes family
T1206 1760-1764 NN denotes BMPs
T1207 1765-1768 VB denotes are
T1208 1769-1774 CD denotes 30–38
T1209 1775-1778 NN denotes kDa
T1210 1779-1786 NN denotes hetero-
T1211 1787-1789 CC denotes or
T1212 1790-1801 JJ denotes homodimeric
T1213 1802-1810 NN denotes proteins
T1214 1811-1821 RB denotes originally
T1215 1822-1832 VB denotes identified
T1216 1833-1835 IN denotes by
T1217 1836-1841 PRP-DOLLAR- denotes their
T1218 1842-1849 NN denotes ability
T1219 1850-1852 TO denotes to
T1220 1853-1859 VB denotes induce
T1221 1860-1867 JJ denotes ectopic
T1222 1868-1877 NN denotes cartilage
T1223 1878-1881 CC denotes and
T1224 1882-1886 NN denotes bone
T1225 1887-1896 NN denotes formation
T1226 1897-1898 -LRB- denotes [
T1227 1898-1901 CD denotes 2,3
T1228 1901-1902 -RRB- denotes ]
T1229 1904-1911 JJ denotes Several
T1230 1912-1919 NN denotes studies
T1231 1920-1924 VB denotes have
T1232 1925-1937 VB denotes demonstrated
T1233 1938-1940 DT denotes an
T1234 1941-1950 JJ denotes essential
T1235 1951-1955 NN denotes role
T1236 1956-1958 IN denotes of
T1237 1959-1964 DT denotes these
T1238 1965-1973 NN denotes proteins
T1239 1974-1980 IN denotes during
T1240 1981-1994 NN denotes embryogenesis
T1241 1994-1995 -COMMA- denotes ,
T1242 1996-1999 CC denotes and
T1243 2000-2004 RB denotes more
T1244 2005-2013 RB denotes recently
T1245 2013-2014 -COMMA- denotes ,
T1246 2015-2019 RB denotes also
T1247 2020-2022 IN denotes in
T1248 2023-2028 JJ denotes adult
T1249 2029-2036 NN denotes tissues
T1250 2037-2038 -LRB- denotes [
T1251 2038-2039 CD denotes 1
T1252 2039-2040 -RRB- denotes ]
T1253 2042-2047 NN denotes TGF-β
T1254 2048-2051 VB denotes has
T1255 2052-2056 VB denotes been
T1256 2057-2068 RB denotes intensively
T1257 2069-2076 VB denotes studied
T1258 2077-2079 IN denotes in
T1259 2080-2086 JJ denotes normal
T1260 2087-2090 CC denotes and
T1261 2091-2100 JJ denotes malignant
T1262 2101-2115 JJ denotes haematopoietic
T1263 2116-2121 NN denotes cells
T1264 2122-2125 CC denotes and
T1265 2126-2128 VB denotes is
T1266 2129-2132 CD denotes one
T1267 2133-2135 IN denotes of
T1268 2136-2139 DT denotes the
T1269 2140-2144 RB denotes most
T1270 2145-2151 JJ denotes potent
T1271 2152-2162 JJ denotes endogenous
T1272 2163-2171 JJ denotes negative
T1273 2172-2182 NN denotes regulators
T1274 2183-2188 VB denotes known
T1275 2189-2191 TO denotes to
T1276 2192-2197 NN denotes date.
T1277 2198-2199 -LRB- denotes [
T1278 2199-2200 CD denotes 4
T1279 2200-2201 -RRB- denotes ]
T1280 2203-2205 IN denotes In
T1281 2206-2214 NN denotes contrast
T1282 2214-2215 -COMMA- denotes ,
T1283 2216-2219 DT denotes the
T1284 2220-2226 NN denotes effect
T1285 2227-2229 IN denotes of
T1286 2230-2234 NN denotes BMPs
T1287 2235-2237 IN denotes in
T1288 2238-2241 DT denotes the
T1289 2242-2248 JJ denotes immune
T1290 2249-2255 NN denotes system
T1291 2256-2259 VB denotes has
T1292 2260-2263 RB denotes not
T1293 2264-2268 VB denotes been
T1294 2269-2275 RB denotes widely
T1295 2276-2288 VB denotes investigated
T1296 2290-2292 IN denotes In
T1297 2293-2297 DT denotes that
T1298 2298-2305 NN denotes respect
T1299 2305-2306 -COMMA- denotes ,
T1300 2307-2311 NN denotes BMP-
T1301 2312-2313 CD denotes 2
T1302 2313-2314 -COMMA- denotes ,
T1303 2315-2317 CD denotes -4
T1304 2318-2321 CC denotes and
T1305 2322-2324 CD denotes -7
T1306 2325-2329 VB denotes have
T1307 2330-2334 VB denotes been
T1308 2335-2340 VB denotes found
T1309 2341-2343 TO denotes to
T1310 2344-2351 VB denotes control
T1311 2352-2367 NN denotes differentiation
T1312 2368-2370 IN denotes of
T1313 2371-2384 JJ denotes hematopoietic
T1314 2385-2389 NN denotes stem
T1315 2390-2395 NN denotes cells
T1316 2396-2397 -LRB- denotes [
T1317 2397-2398 CD denotes 5
T1318 2398-2399 -RRB- denotes ]
T1319 2400-2403 CC denotes and
T1320 2404-2409 JJ denotes early
T1321 2410-2411 NN denotes T
T1322 2412-2416 NN denotes cell
T1323 2417-2428 NN denotes development
T1324 2429-2430 -LRB- denotes [
T1325 2430-2433 CD denotes 6,7
T1326 2433-2434 -RRB- denotes ]
T1327 2436-2441 NN denotes BMP-6
T1328 2442-2445 VB denotes has
T1329 2446-2450 VB denotes been
T1330 2451-2459 VB denotes reported
T1331 2460-2462 TO denotes to
T1332 2463-2469 VB denotes reduce
T1333 2470-2473 DT denotes the
T1334 2474-2480 NN denotes number
T1335 2481-2483 IN denotes of
T1336 2484-2508 JJ denotes cobblestone-area-forming
T1337 2509-2514 NN denotes cells
T1338 2515-2517 IN denotes of
T1339 2518-2524 JJ denotes normal
T1340 2525-2530 JJ denotes human
T1341 2531-2545 JJ denotes haematopoietic
T1342 2546-2551 NN denotes cells
T1343 2552-2553 -LRB- denotes [
T1344 2553-2554 CD denotes 8
T1345 2554-2555 -RRB- denotes ]
T1346 2557-2568 RB denotes Furthermore
T1347 2568-2569 -COMMA- denotes ,
T1348 2570-2575 NN denotes BMP-2
T1349 2575-2576 -COMMA- denotes ,
T1350 2577-2579 CD denotes -4
T1351 2579-2580 -COMMA- denotes ,
T1352 2581-2582 CD denotes 6
T1353 2583-2586 CC denotes and
T1354 2587-2589 CD denotes -7
T1355 2590-2593 VB denotes had
T1356 2594-2596 DT denotes an
T1357 2597-2614 JJ denotes antiproliferative
T1358 2615-2618 CC denotes and
T1359 2619-2620 DT denotes a
T1360 2621-2633 JJ denotes proapoptotic
T1361 2634-2640 NN denotes effect
T1362 2641-2643 IN denotes on
T1363 2644-2652 JJ denotes multiple
T1364 2653-2660 NN denotes myeloma
T1365 2661-2666 NN denotes cells
T1366 2667-2668 -LRB- denotes [
T1367 2668-2672 CD denotes 9-11
T1368 2672-2673 -RRB- denotes ]
T1369 2675-2677 IN denotes In
T1370 2678-2686 NN denotes addition
T1371 2686-2687 -COMMA- denotes ,
T1372 2688-2690 IN denotes by
T1373 2691-2695 NN denotes gene
T1374 2696-2706 NN denotes expression
T1375 2707-2716 NN denotes profiling
T1376 2716-2717 -COMMA- denotes ,
T1377 2718-2723 NN denotes BMP-6
T1378 2724-2737 RB denotes significantly
T1379 2738-2747 VB denotes increased
T1380 2748-2751 DT denotes the
T1381 2752-2762 JJ denotes predictive
T1382 2763-2768 NN denotes value
T1383 2769-2772 IN denotes for
T1384 2773-2774 DT denotes a
T1385 2775-2785 JJ denotes multi-gene
T1386 2786-2795 NN denotes signature
T1387 2796-2800 NN denotes test
T1388 2801-2804 CC denotes and
T1389 2805-2808 VB denotes was
T1390 2809-2819 VB denotes associated
T1391 2820-2824 IN denotes with
T1392 2825-2826 DT denotes a
T1393 2827-2831 JJ denotes poor
T1394 2832-2839 NN denotes outcome
T1395 2840-2842 IN denotes in
T1396 2843-2850 JJ denotes diffuse
T1397 2851-2856 JJ denotes large
T1398 2857-2858 NN denotes B
T1399 2859-2863 NN denotes cell
T1400 2864-2873 NN denotes lymphomas
T1401 2874-2875 -LRB- denotes (
T1402 2875-2880 NN denotes DLBCL
T1403 2880-2881 -RRB- denotes )
T1404 2882-2883 -LRB- denotes [
T1405 2883-2885 CD denotes 12
T1406 2885-2886 -RRB- denotes ]
T1407 2888-2893 NN denotes BMP-6
T1408 2893-2894 -COMMA- denotes ,
T1409 2895-2899 IN denotes like
T1410 2900-2903 DT denotes the
T1411 2904-2909 JJ denotes other
T1412 2910-2913 NN denotes BMP
T1413 2914-2921 NN denotes members
T1414 2921-2922 -COMMA- denotes ,
T1415 2923-2930 NN denotes signals
T1416 2931-2938 IN denotes through
T1417 2939-2947 NN denotes ligation
T1418 2948-2951 CC denotes and
T1419 2952-2969 NN denotes heterodimerzation
T1420 2970-2972 IN denotes of
T1421 2973-2976 NN denotes BMP
T1422 2977-2981 NN denotes type
T1423 2982-2983 CD denotes I
T1424 2984-2985 -LRB- denotes [
T1425 2985-3004 NN denotes activin-like-kinase
T1426 3005-3006 -LRB- denotes (
T1427 3006-3009 NN denotes ALK
T1428 3009-3010 -RRB- denotes )
T1429 3010-3011 -RRB- denotes ]
T1430 3012-3015 CC denotes and
T1431 3016-3020 NN denotes type
T1432 3021-3023 CD denotes II
T1433 3024-3040 NN denotes serine-threonine
T1434 3041-3047 NN denotes kinase
T1435 3048-3057 NN denotes receptors
T1436 3057-3058 -COMMA- denotes ,
T1437 3059-3064 WDT denotes which
T1438 3065-3077 RB denotes subsequently
T1439 3078-3088 VB denotes propagates
T1440 3089-3092 DT denotes the
T1441 3093-3099 NN denotes signal
T1442 3100-3110 RB denotes downstream
T1443 3111-3113 IN denotes by
T1444 3114-3129 VB denotes phosphorylating
T1445 3130-3134 NN denotes Smad
T1446 3135-3143 NN denotes proteins
T1447 3145-3150 NN denotes BMP-6
T1448 3151-3154 MD denotes can
T1449 3155-3161 VB denotes signal
T1450 3162-3169 IN denotes through
T1451 3170-3173 DT denotes the
T1452 3174-3182 NN denotes ligation
T1453 3183-3185 IN denotes of
T1454 3186-3189 DT denotes the
T1455 3190-3194 NN denotes type
T1456 3195-3196 CD denotes I
T1457 3197-3206 NN denotes receptors
T1458 3207-3214 NNP denotes Act-RIA
T1459 3214-3215 -COMMA- denotes ,
T1460 3216-3223 NN denotes BMP-RIA
T1461 3223-3224 -COMMA- denotes ,
T1462 3225-3228 CC denotes and
T1463 3229-3236 NN denotes BMP-RIB
T1464 3237-3240 CC denotes and
T1465 3241-3244 DT denotes the
T1466 3245-3249 NN denotes type
T1467 3250-3252 CD denotes II
T1468 3253-3262 NN denotes receptors
T1469 3263-3270 NN denotes BMP-RII
T1470 3270-3271 -COMMA- denotes ,
T1471 3272-3280 NN denotes Act-RIIA
T1472 3281-3284 CC denotes and
T1473 3285-3293 NN denotes Act-RIIB
T1474 3293-3294 -COMMA- denotes ,
T1475 3295-3300 WDT denotes which
T1476 3301-3305 VB denotes lead
T1477 3306-3308 TO denotes to
T1478 3309-3312 DT denotes the
T1479 3313-3328 NN denotes phosphorylation
T1480 3329-3331 IN denotes of
T1481 3332-3335 DT denotes the
T1482 3336-3344 NN denotes receptor
T1483 3345-3350 NN denotes Smads
T1484 3351-3352 -LRB- denotes (
T1485 3352-3358 NN denotes Smad-1
T1486 3358-3359 -COMMA- denotes ,
T1487 3360-3366 NN denotes Smad-5
T1488 3366-3367 -COMMA- denotes ,
T1489 3368-3371 CC denotes and
T1490 3372-3378 NN denotes Smad-8
T1491 3378-3379 -RRB- denotes )
T1492 3381-3384 DT denotes The
T1493 3385-3387 NN denotes R-
T1494 3388-3393 NN denotes Smads
T1495 3394-3398 RB denotes then
T1496 3399-3403 VB denotes form
T1497 3404-3413 NN denotes complexes
T1498 3414-3418 IN denotes with
T1499 3419-3422 DT denotes the
T1500 3423-3430 NN denotes co-Smad
T1501 3431-3432 -LRB- denotes (
T1502 3432-3437 NN denotes Smad4
T1503 3437-3438 -RRB- denotes )
T1504 3439-3442 CC denotes and
T1505 3443-3446 VB denotes are
T1506 3447-3459 VB denotes translocated
T1507 3460-3464 IN denotes into
T1508 3465-3468 DT denotes the
T1509 3469-3476 NN denotes nucleus
T1510 3477-3482 WRB denotes where
T1511 3483-3487 PRP denotes they
T1512 3488-3493 VB denotes exert
T1513 3494-3498 NN denotes gene
T1514 3499-3509 NN denotes regulation
T1515 3510-3511 -LRB- denotes [
T1516 3511-3515 CD denotes 1,13
T1517 3515-3516 -RRB- denotes ]
T1518 3518-3523 VB denotes Given
T1519 3524-3527 DT denotes the
T1520 3528-3536 VB denotes reported
T1521 3537-3541 NN denotes role
T1522 3542-3544 IN denotes of
T1523 3545-3550 NN denotes BMP-6
T1524 3551-3553 IN denotes in
T1525 3554-3560 NN denotes B-cell
T1526 3561-3573 NN denotes malignancies
T1527 3574-3577 CC denotes and
T1528 3578-3592 JJ denotes haematopoietic
T1529 3593-3603 NN denotes progenitor
T1530 3604-3609 NN denotes cells
T1531 3609-3610 -COMMA- denotes ,
T1532 3611-3613 PRP denotes we
T1533 3614-3620 VB denotes wanted
T1534 3621-3623 TO denotes to
T1535 3624-3631 VB denotes explore
T1536 3632-3635 PRP-DOLLAR- denotes its
T1537 3636-3645 JJ denotes potential
T1538 3646-3650 NN denotes role
T1539 3651-3653 IN denotes in
T1540 3654-3660 JJ denotes normal
T1541 3661-3666 JJ denotes human
T1542 3667-3668 NN denotes B
T1543 3669-3674 NN denotes cells
T1544 3676-3678 PRP denotes We
T1545 3679-3686 VB denotes studied
T1546 3687-3690 DT denotes the
T1547 3691-3698 NN denotes effects
T1548 3699-3701 IN denotes of
T1549 3702-3707 NN denotes BMP-6
T1550 3708-3710 IN denotes on
T1551 3711-3724 NN denotes proliferation
T1552 3725-3728 CC denotes and
T1553 3729-3738 NN denotes apoptosis
T1554 3739-3741 IN denotes on
T1555 3742-3749 VB denotes resting
T1556 3750-3753 CC denotes and
T1557 3754-3764 VB denotes stimulated
T1558 3765-3766 NN denotes B
T1559 3767-3772 NN denotes cells
T1560 3774-3785 RB denotes Furthermore
T1561 3785-3786 -COMMA- denotes ,
T1562 3787-3790 DT denotes the
T1563 3791-3801 NN denotes expression
T1564 3802-3804 IN denotes of
T1565 3805-3808 NN denotes BMP
T1566 3809-3818 NN denotes receptors
T1567 3819-3822 CC denotes and
T1568 3823-3828 NN denotes BMP-6
T1569 3829-3836 VB denotes induced
T1570 3837-3847 NN denotes activation
T1571 3848-3850 IN denotes of
T1572 3851-3854 DT denotes the
T1573 3855-3859 NN denotes Smad
T1574 3860-3870 NN denotes signalling
T1575 3871-3878 NN denotes pathway
T1576 3879-3883 IN denotes with
T1577 3884-3894 JJ denotes subsequent
T1578 3895-3905 NN denotes regulation
T1579 3906-3908 IN denotes of
T1580 3909-3912 DT denotes the
T1581 3913-3919 NN denotes target
T1582 3920-3925 NN denotes genes
T1583 3926-3933 NN denotes Id1–Id4
T1584 3933-3934 -COMMA- denotes ,
T1585 3935-3939 VB denotes were
T1586 3940-3948 VB denotes resolved
T1587 3950-3957 RB denotes Finally
T1588 3957-3958 -COMMA- denotes ,
T1589 3959-3961 PRP denotes we
T1590 3962-3974 VB denotes investigated
T1591 3975-3982 IN denotes whether
T1592 3983-3984 NN denotes B
T1593 3985-3990 NN denotes cells
T1594 3991-3995 RB denotes also
T1595 3996-4000 VB denotes were
T1596 4001-4008 JJ denotes capable
T1597 4009-4011 IN denotes of
T1598 4012-4021 VB denotes producing
T1599 4022-4027 NN denotes BMP-6
T2653 4039-4044 NN denotes BMP-6
T2654 4045-4053 VB denotes inhibits
T2655 4054-4062 NN denotes anti-IgM
T2656 4063-4070 VB denotes induced
T2657 4071-4084 NN denotes proliferation
T2658 4085-4087 IN denotes of
T2659 4088-4093 JJ denotes human
T2660 4094-4095 NN denotes B
T2661 4096-4101 NN denotes cells
T2662 4102-4105 DT denotes The
T2663 4106-4113 NN denotes effects
T2664 4114-4116 IN denotes of
T2665 4117-4122 NN denotes BMP-6
T2666 4123-4125 IN denotes on
T2667 4126-4132 JJ denotes normal
T2668 4133-4136 CC denotes and
T2669 4137-4147 JJ denotes neoplastic
T2670 4148-4161 JJ denotes hematopoietic
T2671 4162-4167 NN denotes cells
T2672 4168-4176 VB denotes prompted
T2673 4177-4179 PRP denotes us
T2674 4180-4182 TO denotes to
T2675 4183-4194 VB denotes investigate
T2676 4195-4198 DT denotes the
T2677 4199-4206 NN denotes effects
T2678 4207-4209 IN denotes of
T2679 4210-4215 NN denotes BMP-6
T2680 4216-4218 IN denotes on
T2681 4219-4225 JJ denotes normal
T2682 4226-4231 JJ denotes human
T2683 4232-4233 NN denotes B
T2684 4234-4239 NN denotes cells
T2685 4241-4244 DT denotes All
T2686 4245-4256 NN denotes experiments
T2687 4257-4259 IN denotes in
T2688 4260-4264 DT denotes this
T2689 4265-4270 NN denotes study
T2690 4271-4275 VB denotes were
T2691 4276-4285 VB denotes performed
T2692 4286-4291 IN denotes under
T2693 4292-4302 JJ denotes serum-free
T2694 4303-4313 NN denotes conditions
T2695 4314-4316 IN denotes as
T2696 4317-4320 NN denotes FCS
T2697 4321-4324 VB denotes has
T2698 4325-4329 VB denotes been
T2699 4330-4335 VB denotes shown
T2700 4336-4338 TO denotes to
T2701 4339-4348 VB denotes interfere
T2702 4349-4353 IN denotes with
T2703 4354-4368 JJ denotes BMP-signalling
T2704 4369-4370 -LRB- denotes [
T2705 4370-4372 CD denotes 14
T2706 4372-4373 -RRB- denotes ]
T2707 4373-4374 -LRB- denotes (
T2708 4374-4377 JJ denotes own
T2709 4378-4390 NN denotes observations
T2710 4390-4391 -RRB- denotes )
T2711 4393-4395 TO denotes To
T2712 4396-4401 VB denotes study
T2713 4402-4405 DT denotes the
T2714 4406-4412 NN denotes effect
T2715 4413-4415 IN denotes of
T2716 4416-4421 NN denotes BMP-6
T2717 4422-4424 IN denotes on
T2718 4425-4438 NN denotes proliferation
T2719 4438-4439 -COMMA- denotes ,
T2720 4440-4447 NN denotes B-cells
T2721 4448-4452 IN denotes from
T2722 4453-4460 JJ denotes healthy
T2723 4461-4471 NN denotes volunteers
T2724 4472-4476 VB denotes were
T2725 4477-4487 VB denotes stimulated
T2726 4488-4492 IN denotes with
T2727 4493-4501 JJ denotes anti-IgM
T2728 4502-4508 CC denotes and/or
T2729 4509-4514 NN denotes CD40L
T2730 4515-4517 IN denotes in
T2731 4518-4521 DT denotes the
T2732 4522-4530 NN denotes presence
T2733 4531-4533 CC denotes or
T2734 4534-4541 NN denotes absence
T2735 4542-4544 IN denotes of
T2736 4545-4550 NN denotes BMP-6
T2737 4551-4554 IN denotes for
T2738 4555-4560 CD denotes three
T2739 4561-4565 NN denotes days
T2740 4567-4569 PRP denotes We
T2741 4570-4575 VB denotes found
T2742 4576-4580 IN denotes that
T2743 4581-4586 NN denotes BMP-6
T2744 4587-4590 VB denotes led
T2745 4591-4593 TO denotes to
T2746 4594-4595 DT denotes a
T2747 4596-4598 CD denotes 35
T2748 4598-4599 NN denotes %
T2749 4600-4604 JJ denotes mean
T2750 4605-4614 NN denotes reduction
T2751 4615-4617 IN denotes of
T2752 4618-4627 JJ denotes anti-IgM-
T2753 4628-4635 VB denotes induced
T2754 4636-4639 NN denotes DNA
T2755 4640-4649 NN denotes synthesis
T2756 4650-4651 -LRB- denotes (
T2757 4651-4652 NN denotes n
T2758 4653-4654 SYM denotes =
T2759 4655-4656 CD denotes 8
T2760 4656-4657 -COLON- denotes ;
T2761 4658-4659 NN denotes p
T2762 4660-4661 IN denotes ≤
T2763 4662-4668 CD denotes 0.0002
T2764 4668-4669 -COMMA- denotes ,
T2765 4670-4676 NN denotes Figure
T2766 4677-4679 NN denotes 1A
T2767 4679-4680 -RRB- denotes )
T2768 4682-4689 JJ denotes Similar
T2769 4690-4697 NN denotes results
T2770 4698-4702 VB denotes were
T2771 4703-4711 VB denotes obtained
T2772 4712-4715 IN denotes for
T2773 4716-4717 NN denotes B
T2774 4718-4723 NN denotes cells
T2775 4724-4731 VB denotes treated
T2776 4732-4736 IN denotes with
T2777 4737-4745 JJ denotes anti-IgM
T2778 4746-4749 CC denotes and
T2779 4750-4755 NN denotes CD40L
T2780 4756-4757 -LRB- denotes (
T2781 4757-4759 CD denotes 26
T2782 4759-4760 NN denotes %
T2783 4761-4765 JJ denotes mean
T2784 4766-4775 NN denotes reduction
T2785 4775-4776 -COMMA- denotes ,
T2786 4777-4778 NN denotes n
T2787 4779-4780 JJ denotes =
T2788 4781-4782 CD denotes 6
T2789 4782-4783 -COLON- denotes ;
T2790 4784-4785 NN denotes p
T2791 4786-4787 CC denotes ≤
T2792 4788-4793 CD denotes 0.023
T2793 4793-4794 -RRB- denotes )
T2794 4796-4799 DT denotes The
T2795 4800-4813 JJ denotes BMP-6-induced
T2796 4814-4824 NN denotes inhibition
T2797 4825-4827 IN denotes of
T2798 4828-4841 NN denotes proliferation
T2799 4842-4845 VB denotes was
T2800 4846-4860 JJ denotes dose-dependent
T2801 4861-4863 IN denotes in
T2802 4864-4868 CC denotes both
T2803 4869-4879 JJ denotes peripheral
T2804 4880-4881 NN denotes B
T2805 4882-4887 NN denotes cells
T2806 4888-4889 -LRB- denotes (
T2807 4889-4895 NN denotes Figure
T2808 4896-4898 NN denotes 1B
T2809 4898-4899 -RRB- denotes )
T2810 4900-4903 CC denotes and
T2811 4904-4907 DT denotes the
T2812 4908-4915 NN denotes Burkitt
T2813 4916-4924 NN denotes lymphoma
T2814 4925-4929 NN denotes cell
T2815 4930-4934 NN denotes line
T2816 4935-4940 NN denotes Ramos
T2817 4941-4942 -LRB- denotes (
T2818 4942-4944 CD denotes 40
T2819 4944-4945 NN denotes %
T2820 4946-4955 NN denotes reduction
T2821 4956-4958 IN denotes of
T2822 4959-4962 NN denotes DNA
T2823 4963-4972 NN denotes synthesis
T2824 4972-4973 -COMMA- denotes ,
T2825 4974-4980 NN denotes Figure
T2826 4981-4983 NN denotes 1C
T2827 4983-4984 -RRB- denotes )
T2828 4986-4989 DT denotes The
T2829 4990-4995 NN denotes BMP-6
T2830 4996-5003 NN denotes effects
T2831 5004-5009 MD denotes could
T2832 5010-5012 VB denotes be
T2833 5013-5021 VB denotes reversed
T2834 5022-5024 IN denotes by
T2835 5025-5033 NN denotes addition
T2836 5034-5036 IN denotes of
T2837 5037-5040 DT denotes the
T2838 5041-5054 JJ denotes extracellular
T2839 5055-5064 NN denotes inhibitor
T2840 5065-5071 NN denotes Noggin
T2841 5072-5073 -LRB- denotes (
T2842 5073-5079 NN denotes Figure
T2843 5080-5082 NN denotes 1D
T2844 5082-5083 -RRB- denotes )
T2845 5085-5094 RB denotes Similarly
T2846 5094-5095 -COMMA- denotes ,
T2847 5096-5097 DT denotes a
T2848 5098-5109 NN denotes combination
T2849 5110-5112 IN denotes of
T2850 5113-5116 DT denotes the
T2851 5117-5124 JJ denotes soluble
T2852 5125-5128 NN denotes BMP
T2853 5129-5138 NN denotes receptors
T2854 5139-5149 NN denotes BMP-RIB-Fc
T2855 5150-5153 CC denotes and
T2856 5154-5164 NN denotes BMP-RII-Fc
T2857 5165-5169 RB denotes also
T2858 5170-5181 VB denotes neutralized
T2859 5182-5185 DT denotes the
T2860 5186-5193 NN denotes effects
T2861 5194-5196 IN denotes of
T2862 5197-5202 NN denotes BMP-6
T2863 5203-5204 -LRB- denotes (
T2864 5204-5208 NN denotes data
T2865 5209-5212 RB denotes not
T2866 5213-5218 VB denotes shown
T2867 5218-5219 -RRB- denotes )
T2868 5221-5225 RB denotes Next
T2869 5225-5226 -COMMA- denotes ,
T2870 5227-5229 PRP denotes we
T2871 5230-5236 VB denotes wanted
T2872 5237-5239 TO denotes to
T2873 5240-5244 VB denotes test
T2874 5245-5252 IN denotes whether
T2875 5253-5258 NN denotes BMP-6
T2876 5259-5262 VB denotes had
T2877 5263-5272 JJ denotes different
T2878 5273-5279 NN denotes effect
T2879 5280-5282 IN denotes on
T2880 5283-5288 NN denotes naïve
T2881 5289-5292 CC denotes and
T2882 5293-5299 NN denotes memory
T2883 5300-5301 NN denotes B
T2884 5302-5307 NN denotes cells
T2885 5309-5314 NN denotes Naïve
T2886 5315-5316 -LRB- denotes (
T2887 5316-5326 JJ denotes CD19+CD27-
T2888 5326-5327 -RRB- denotes )
T2889 5328-5331 CC denotes and
T2890 5332-5338 NN denotes memory
T2891 5339-5340 -LRB- denotes (
T2892 5340-5350 JJ denotes CD19+CD27+
T2893 5350-5351 -RRB- denotes )
T2894 5352-5353 NN denotes B
T2895 5354-5359 NN denotes cells
T2896 5360-5364 VB denotes were
T2897 5365-5373 VB denotes isolated
T2898 5374-5378 IN denotes from
T2899 5379-5389 JJ denotes peripheral
T2900 5390-5395 NN denotes blood
T2901 5396-5398 IN denotes by
T2902 5399-5403 NN denotes cell
T2903 5404-5411 NN denotes sorting
T2904 5412-5414 IN denotes of
T2905 5415-5434 JJ denotes immunobead-isolated
T2906 5435-5440 JJ denotes CD19+
T2907 5441-5442 NN denotes B
T2908 5443-5448 NN denotes cells
T2909 5449-5450 -LRB- denotes [
T2910 5450-5452 CD denotes 15
T2911 5452-5453 -RRB- denotes ]
T2912 5453-5454 -COMMA- denotes ,
T2913 5455-5458 CC denotes and
T2914 5459-5465 VB denotes tested
T2915 5466-5469 IN denotes for
T2916 5470-5475 PRP-DOLLAR- denotes their
T2917 5476-5484 NN denotes capacity
T2918 5485-5487 TO denotes to
T2919 5488-5499 VB denotes proliferate
T2920 5500-5502 IN denotes in
T2921 5503-5506 DT denotes the
T2922 5507-5515 NN denotes presence
T2923 5516-5518 IN denotes of
T2924 5519-5524 NN denotes BMP-6
T2925 5526-5533 RB denotes However
T2926 5533-5534 -COMMA- denotes ,
T2927 5535-5540 NN denotes BMP-6
T2928 5541-5550 VB denotes inhibited
T2929 5551-5559 NN denotes anti-IgM
T2930 5560-5567 VB denotes induced
T2931 5568-5571 NN denotes DNA
T2932 5572-5581 NN denotes synthesis
T2933 5582-5584 IN denotes in
T2934 5585-5588 DT denotes the
T2935 5589-5592 CD denotes two
T2936 5593-5607 NN denotes subpopulations
T2937 5608-5610 TO denotes to
T2938 5611-5612 DT denotes a
T2939 5613-5620 JJ denotes similar
T2940 5621-5627 NN denotes extent
T2941 5627-5628 -COMMA- denotes ,
T2942 5629-5633 IN denotes with
T2943 5634-5635 DT denotes a
T2944 5636-5640 JJ denotes mean
T2945 5641-5650 NN denotes reduction
T2946 5651-5653 IN denotes of
T2947 5654-5667 NN denotes DNA-synthesis
T2948 5668-5670 IN denotes of
T2949 5671-5673 CD denotes 45
T2950 5673-5674 NN denotes %
T2951 5675-5676 -LRB- denotes (
T2952 5676-5677 NN denotes n
T2953 5678-5679 SYM denotes =
T2954 5680-5681 CD denotes 5
T2955 5681-5682 -COLON- denotes ;
T2956 5683-5684 NN denotes p
T2957 5685-5686 CC denotes ≤
T2958 5687-5692 CD denotes 0,004
T2959 5692-5693 -RRB- denotes )
T2960 5694-5697 IN denotes for
T2961 5698-5703 NN denotes naïve
T2962 5704-5705 NN denotes B
T2963 5706-5711 NN denotes cells
T2964 5712-5715 CC denotes and
T2965 5716-5718 CD denotes 48
T2966 5718-5719 NN denotes %
T2967 5720-5721 -LRB- denotes (
T2968 5721-5722 NN denotes n
T2969 5723-5724 SYM denotes =
T2970 5725-5726 CD denotes 5
T2971 5726-5727 -COLON- denotes ;
T2972 5728-5729 NN denotes p
T2973 5730-5731 CC denotes ≤
T2974 5732-5737 CD denotes 0,001
T2975 5737-5738 -RRB- denotes )
T2976 5739-5742 IN denotes for
T2977 5743-5749 NN denotes memory
T2978 5750-5751 NN denotes B
T2979 5752-5757 NN denotes cells
T2980 5758-5759 -LRB- denotes (
T2981 5759-5765 NN denotes Figure
T2982 5766-5768 NN denotes 1E
T2983 5768-5769 -RRB- denotes )
T3594 5772-5777 NN denotes BMP-6
T3595 5778-5785 VB denotes induces
T3596 5786-5790 NN denotes cell
T3597 5791-5796 NN denotes death
T3598 5797-5799 IN denotes in
T3599 5800-5805 JJ denotes human
T3600 5806-5812 NN denotes memory
T3601 5813-5814 NN denotes B
T3602 5815-5820 NN denotes cells
T3603 5821-5824 CC denotes and
T3604 5825-5830 NN denotes Ramos
T3605 5831-5836 NN denotes cells
T3606 5837-5841 RB denotes Next
T3607 5841-5842 -COMMA- denotes ,
T3608 5843-5845 PRP denotes we
T3609 5846-5852 VB denotes wanted
T3610 5853-5855 TO denotes to
T3611 5856-5865 VB denotes establish
T3612 5866-5873 IN denotes whether
T3613 5874-5879 NN denotes BMP-6
T3614 5880-5884 RB denotes also
T3615 5885-5890 MD denotes could
T3616 5891-5897 VB denotes affect
T3617 5898-5901 DT denotes the
T3618 5902-5911 NN denotes viability
T3619 5912-5914 IN denotes of
T3620 5915-5921 JJ denotes normal
T3621 5922-5923 NN denotes B
T3622 5924-5929 NN denotes cells
T3623 5931-5935 NN denotes Cell
T3624 5936-5945 NN denotes viability
T3625 5946-5949 VB denotes was
T3626 5950-5960 VB denotes determined
T3627 5961-5963 IN denotes by
T3628 5964-5973 NN denotes propidium
T3629 5974-5980 NN denotes iodide
T3630 5981-5982 -LRB- denotes (
T3631 5982-5984 NN denotes PI
T3632 5984-5985 -RRB- denotes )
T3633 5986-5994 NN denotes staining
T3634 5995-6000 IN denotes after
T3635 6001-6008 NN denotes culture
T3636 6009-6013 IN denotes with
T3637 6014-6016 CC denotes or
T3638 6017-6024 IN denotes without
T3639 6025-6030 NN denotes BMP-6
T3640 6031-6034 IN denotes for
T3641 6035-6037 CD denotes 48
T3642 6038-6043 NN denotes hours
T3643 6045-6058 RB denotes Interestingly
T3644 6058-6059 -COMMA- denotes ,
T3645 6060-6065 NN denotes BMP-6
T3646 6066-6072 VB denotes showed
T3647 6073-6074 DT denotes a
T3648 6075-6080 JJ denotes small
T3649 6080-6081 -COMMA- denotes ,
T3650 6082-6085 CC denotes but
T3651 6086-6098 JJ denotes reproducible
T3652 6099-6103 JJ denotes mean
T3653 6104-6112 NN denotes increase
T3654 6113-6115 IN denotes of
T3655 6116-6120 NN denotes cell
T3656 6121-6126 NN denotes death
T3657 6127-6131 IN denotes from
T3658 6132-6134 CD denotes 17
T3659 6135-6137 TO denotes to
T3660 6138-6140 CD denotes 23
T3661 6140-6141 NN denotes %
T3662 6142-6143 -LRB- denotes (
T3663 6143-6144 NN denotes n
T3664 6145-6146 SYM denotes =
T3665 6147-6148 CD denotes 5
T3666 6148-6149 -COLON- denotes ;
T3667 6150-6151 NN denotes p
T3668 6152-6153 CC denotes ≤
T3669 6154-6159 CD denotes 0,003
T3670 6159-6160 -RRB- denotes )
T3671 6161-6163 IN denotes in
T3672 6164-6172 JJ denotes anti-IgM
T3673 6173-6183 VB denotes stimulated
T3674 6184-6189 JJ denotes CD27+
T3675 6190-6196 NN denotes memory
T3676 6197-6198 NN denotes B
T3677 6199-6204 NN denotes cells
T3678 6206-6217 RB denotes Furthermore
T3679 6217-6218 -COMMA- denotes ,
T3680 6219-6224 NN denotes Ramos
T3681 6225-6230 NN denotes cells
T3682 6231-6237 VB denotes showed
T3683 6238-6239 DT denotes a
T3684 6240-6244 JJ denotes mean
T3685 6245-6253 NN denotes increase
T3686 6254-6256 IN denotes in
T3687 6257-6261 NN denotes cell
T3688 6262-6267 NN denotes death
T3689 6268-6272 IN denotes from
T3690 6273-6275 CD denotes 20
T3691 6276-6278 TO denotes to
T3692 6279-6281 CD denotes 50
T3693 6281-6282 NN denotes %
T3694 6283-6284 -LRB- denotes (
T3695 6284-6285 NN denotes n
T3696 6286-6287 SYM denotes =
T3697 6288-6289 CD denotes 3
T3698 6289-6290 -COMMA- denotes ,
T3699 6291-6292 NN denotes p
T3700 6293-6294 JJ denotes <
T3701 6295-6300 CD denotes 0,001
T3702 6300-6301 -COMMA- denotes ,
T3703 6302-6308 NN denotes figure
T3704 6309-6310 CD denotes 3
T3705 6310-6311 -RRB- denotes )
T3706 6312-6317 IN denotes after
T3707 6318-6323 NN denotes BMP-6
T3708 6324-6333 NN denotes treatment
T3709 6335-6337 IN denotes In
T3710 6338-6346 NN denotes contrast
T3711 6346-6347 -COMMA- denotes ,
T3712 6348-6352 NN denotes cell
T3713 6353-6358 NN denotes death
T3714 6359-6361 IN denotes of
T3715 6362-6367 JJ denotes total
T3716 6368-6373 JJ denotes CD19+
T3717 6374-6379 NN denotes cells
T3718 6380-6381 -LRB- denotes (
T3719 6381-6382 NN denotes n
T3720 6383-6384 JJ denotes =
T3721 6385-6386 CD denotes 6
T3722 6386-6387 -COLON- denotes ;
T3723 6388-6389 NN denotes p
T3724 6390-6391 VB denotes ≤
T3725 6392-6396 CD denotes 0,32
T3726 6396-6397 -COLON- denotes ;
T3727 6398-6402 NN denotes data
T3728 6403-6406 RB denotes not
T3729 6407-6412 VB denotes shown
T3730 6412-6413 -RRB- denotes )
T3731 6414-6416 CC denotes or
T3732 6417-6426 NN denotes CD27-IgG-
T3733 6427-6432 NN denotes naïve
T3734 6433-6434 NN denotes B
T3735 6435-6440 NN denotes cells
T3736 6441-6444 VB denotes was
T3737 6445-6448 RB denotes not
T3738 6449-6462 RB denotes significantly
T3739 6463-6471 VB denotes affected
T3740 6472-6473 -LRB- denotes (
T3741 6473-6474 NN denotes n
T3742 6475-6476 SYM denotes =
T3743 6477-6478 CD denotes 5
T3744 6478-6479 -COLON- denotes ;
T3745 6480-6481 NN denotes p
T3746 6482-6483 IN denotes ≤
T3747 6484-6488 CD denotes 0,65
T3748 6488-6489 -COMMA- denotes ,
T3749 6490-6496 NN denotes figure
T3750 6497-6498 CD denotes 2
T3751 6498-6499 -RRB- denotes )
T4059 6502-6507 JJ denotes Human
T4060 6508-6509 NN denotes B
T4061 6510-6515 NN denotes cells
T4062 6516-6523 VB denotes express
T4063 6524-6529 NN denotes BMP-6
T4064 6530-6539 NN denotes receptors
T4065 6540-6548 JJ denotes Detailed
T4066 6549-6558 NN denotes knowledge
T4067 6559-6568 VB denotes regarding
T4068 6569-6579 NN denotes expression
T4069 6580-6582 IN denotes of
T4070 6583-6592 JJ denotes different
T4071 6593-6596 NN denotes BMP
T4072 6597-6606 NN denotes receptors
T4073 6607-6609 IN denotes in
T4074 6610-6611 NN denotes B
T4075 6612-6617 NN denotes cells
T4076 6618-6620 VB denotes is
T4077 6621-6630 RB denotes currently
T4078 6631-6634 RB denotes not
T4079 6635-6644 JJ denotes available
T4080 6646-6648 TO denotes To
T4081 6649-6656 RB denotes further
T4082 6657-6666 VB denotes elucidate
T4083 6667-6670 DT denotes the
T4084 6671-6675 NN denotes role
T4085 6676-6678 IN denotes of
T4086 6679-6683 NN denotes BMPs
T4087 6684-6686 IN denotes in
T4088 6687-6692 JJ denotes human
T4089 6693-6694 NN denotes B
T4090 6695-6700 NN denotes cells
T4091 6700-6701 -COMMA- denotes ,
T4092 6702-6704 PRP denotes we
T4093 6705-6714 VB denotes performed
T4094 6715-6722 JJ denotes western
T4095 6723-6727 NN denotes blot
T4096 6728-6736 NN denotes analysis
T4097 6737-6740 IN denotes for
T4098 6741-6745 NN denotes type
T4099 6746-6747 CD denotes I
T4100 6748-6751 CC denotes and
T4101 6752-6756 NN denotes type
T4102 6757-6759 CD denotes II
T4103 6760-6763 NN denotes BMP
T4104 6764-6773 NN denotes receptors
T4105 6775-6779 DT denotes This
T4106 6780-6788 NN denotes analysis
T4107 6789-6797 VB denotes revealed
T4108 6798-6802 IN denotes that
T4109 6803-6806 DT denotes the
T4110 6807-6811 NN denotes type
T4111 6812-6813 CD denotes I
T4112 6814-6823 NN denotes receptors
T4113 6824-6831 NNP denotes Act-RIA
T4114 6831-6832 -COMMA- denotes ,
T4115 6833-6840 NN denotes BMP-RIB
T4116 6841-6844 CC denotes and
T4117 6845-6848 DT denotes the
T4118 6849-6853 NN denotes type
T4119 6854-6856 CD denotes II
T4120 6857-6866 NN denotes receptors
T4121 6867-6874 NN denotes BMP-RII
T4122 6875-6878 CC denotes and
T4123 6879-6887 NN denotes Act-RIIb
T4124 6888-6891 VB denotes are
T4125 6892-6901 VB denotes expressed
T4126 6902-6904 IN denotes on
T4127 6905-6912 VB denotes resting
T4128 6913-6918 JJ denotes human
T4129 6919-6926 NN denotes B-cells
T4130 6927-6928 -LRB- denotes (
T4131 6928-6934 NN denotes Figure
T4132 6935-6936 CD denotes 4
T4133 6936-6937 -RRB- denotes )
T4134 6939-6944 NN denotes Ramos
T4135 6945-6950 NN denotes cells
T4136 6951-6960 VB denotes expressed
T4137 6961-6964 DT denotes the
T4138 6965-6969 NN denotes type
T4139 6970-6971 CD denotes I
T4140 6972-6981 NN denotes receptors
T4141 6982-6989 NN denotes Act-RIA
T4142 6989-6990 -COMMA- denotes ,
T4143 6991-6997 RB denotes weakly
T4144 6998-7005 NN denotes BMP-RIB
T4145 7006-7009 CC denotes and
T4146 7010-7013 DT denotes the
T4147 7014-7018 NN denotes type
T4148 7019-7021 CD denotes II
T4149 7022-7030 NN denotes receptor
T4150 7031-7038 NN denotes BMP-RII
T4151 7038-7039 -COMMA- denotes ,
T4152 7040-7043 CC denotes but
T4153 7044-7048 RB denotes more
T4154 7049-7055 RB denotes weakly
T4155 7056-7060 IN denotes than
T4156 7061-7067 JJ denotes normal
T4157 7068-7069 NN denotes B
T4158 7070-7075 NN denotes cells
T4159 7076-7077 -LRB- denotes (
T4160 7077-7083 NN denotes Figure
T4161 7084-7085 CD denotes 4
T4162 7085-7086 -RRB- denotes )
T4163 7088-7092 NN denotes HL60
T4164 7093-7098 NN denotes cells
T4165 7099-7103 VB denotes were
T4166 7104-7108 VB denotes used
T4167 7109-7112 IN denotes for
T4168 7113-7123 NN denotes comparison
T4169 7124-7127 CC denotes and
T4170 7128-7134 RB denotes weakly
T4171 7135-7144 VB denotes expressed
T4172 7145-7152 NN denotes Act-RIA
T4173 7153-7156 CC denotes and
T4174 7157-7164 NN denotes BMP-RII
T4175 7166-7171 VB denotes Taken
T4176 7172-7180 RB denotes together
T4177 7180-7181 -COMMA- denotes ,
T4178 7182-7187 DT denotes these
T4179 7188-7192 NN denotes data
T4180 7193-7197 VB denotes show
T4181 7198-7202 IN denotes that
T4182 7203-7209 JJ denotes normal
T4183 7210-7215 JJ denotes human
T4184 7216-7217 NN denotes B
T4185 7218-7223 NN denotes cells
T4186 7224-7227 CC denotes and
T4187 7228-7233 NN denotes Ramos
T4188 7234-7239 NN denotes cells
T4189 7240-7247 VB denotes express
T4190 7248-7249 DT denotes a
T4191 7250-7253 NN denotes set
T4192 7254-7256 IN denotes of
T4193 7257-7260 NN denotes BMP
T4194 7261-7270 NN denotes receptors
T4195 7270-7271 -COMMA- denotes ,
T4196 7272-7282 RB denotes previously
T4197 7283-7288 VB denotes shown
T4198 7289-7291 TO denotes to
T4199 7292-7296 VB denotes bind
T4200 7297-7302 NN denotes BMP-6
T4201 7303-7304 -LRB- denotes [
T4202 7304-7306 CD denotes 16
T4203 7306-7307 -RRB- denotes ]
T4625 7310-7315 NN denotes BMP-6
T4626 7316-7323 VB denotes induces
T4627 7324-7339 NN denotes phosphorylation
T4628 7340-7342 IN denotes of
T4629 7343-7352 NN denotes Smad1/5/8
T4630 7353-7357 IN denotes Upon
T4631 7358-7364 NN denotes ligand
T4632 7365-7372 NN denotes binding
T4633 7372-7373 -COMMA- denotes ,
T4634 7374-7377 DT denotes the
T4635 7378-7382 NN denotes type
T4636 7383-7385 CD denotes II
T4637 7386-7394 NN denotes receptor
T4638 7395-7414 VB denotes transphosphorylates
T4639 7415-7418 CC denotes and
T4640 7419-7428 VB denotes activates
T4641 7429-7432 DT denotes the
T4642 7433-7437 NN denotes type
T4643 7438-7439 CD denotes I
T4644 7440-7448 NN denotes receptor
T4645 7450-7454 NN denotes Type
T4646 7455-7456 CD denotes I
T4647 7457-7466 NN denotes receptors
T4648 7467-7470 MD denotes can
T4649 7471-7477 VB denotes signal
T4650 7478-7481 IN denotes via
T4651 7482-7489 JJ denotes several
T4652 7490-7498 NN denotes pathways
T4653 7500-7502 PRP denotes We
T4654 7503-7511 VB denotes examined
T4655 7512-7515 DT denotes the
T4656 7516-7522 NN denotes effect
T4657 7523-7525 IN denotes of
T4658 7526-7531 NN denotes BMP-6
T4659 7532-7534 IN denotes on
T4660 7535-7539 NN denotes Smad
T4661 7540-7555 NN denotes phosphorylation
T4662 7555-7556 -COMMA- denotes ,
T4663 7557-7559 IN denotes as
T4664 7560-7563 DT denotes the
T4665 7564-7574 NN denotes activation
T4666 7575-7577 IN denotes of
T4667 7578-7582 NN denotes Smad
T4668 7583-7585 VB denotes is
T4669 7586-7596 VB denotes considered
T4670 7597-7599 TO denotes to
T4671 7600-7602 VB denotes be
T4672 7603-7604 DT denotes a
T4673 7605-7610 JJ denotes major
T4674 7611-7621 NN denotes signalling
T4675 7622-7629 NN denotes pathway
T4676 7630-7633 IN denotes for
T4677 7634-7638 NN denotes BMPs
T4678 7639-7640 -LRB- denotes [
T4679 7640-7642 CD denotes 17
T4680 7642-7643 -RRB- denotes ]
T4681 7645-7646 NN denotes B
T4682 7647-7652 NN denotes cells
T4683 7653-7657 VB denotes were
T4684 7658-7666 VB denotes cultured
T4685 7667-7669 IN denotes in
T4686 7670-7680 JJ denotes serum-free
T4687 7681-7686 NN denotes media
T4688 7687-7691 IN denotes over
T4689 7692-7697 NN denotes night
T4690 7698-7701 CC denotes and
T4691 7702-7706 RB denotes then
T4692 7707-7714 VB denotes treated
T4693 7715-7719 IN denotes with
T4694 7720-7725 NN denotes BMP-6
T4695 7726-7729 IN denotes for
T4696 7730-7737 JJ denotes various
T4697 7738-7742 NN denotes time
T4698 7743-7749 NN denotes points
T4699 7751-7756 JJ denotes Total
T4700 7757-7764 NN denotes protein
T4701 7765-7772 NN denotes lysates
T4702 7773-7777 VB denotes were
T4703 7778-7786 VB denotes prepared
T4704 7786-7787 -COMMA- denotes ,
T4705 7788-7791 CC denotes and
T4706 7792-7795 DT denotes the
T4707 7796-7803 NN denotes amounts
T4708 7804-7806 IN denotes of
T4709 7807-7810 DT denotes the
T4710 7811-7825 JJ denotes phosphorylated
T4711 7826-7831 NN denotes forms
T4712 7832-7834 IN denotes of
T4713 7835-7844 NN denotes Smad1/5/8
T4714 7845-7849 VB denotes were
T4715 7850-7860 VB denotes determined
T4716 7861-7863 IN denotes by
T4717 7864-7871 NN denotes western
T4718 7872-7876 NN denotes blot
T4719 7877-7885 NN denotes analysis
T4720 7887-7900 RB denotes Interestingly
T4721 7900-7901 -COMMA- denotes ,
T4722 7902-7911 NN denotes treatment
T4723 7912-7916 IN denotes with
T4724 7917-7920 CD denotes 500
T4725 7921-7926 NN denotes ng/ml
T4726 7927-7932 NN denotes BMP-6
T4727 7933-7940 VB denotes induced
T4728 7941-7956 NN denotes phosphorylation
T4729 7957-7959 IN denotes of
T4730 7960-7965 NNP denotes Smad.
T4731 7966-7969 DT denotes The
T4732 7970-7975 NN denotes BMP-6
T4733 7976-7983 VB denotes induced
T4734 7984-7999 NN denotes phosphorylation
T4735 8000-8003 VB denotes was
T4736 8004-8008 JJ denotes high
T4737 8009-8011 IN denotes at
T4738 8012-8015 DT denotes the
T4739 8016-8024 JJ denotes earliest
T4740 8025-8029 NN denotes time
T4741 8030-8035 NN denotes point
T4742 8036-8042 VB denotes tested
T4743 8043-8044 -LRB- denotes (
T4744 8044-8046 CD denotes 15
T4745 8047-8054 NN denotes minutes
T4746 8054-8055 -RRB- denotes )
T4747 8055-8056 -COMMA- denotes ,
T4748 8057-8060 CC denotes and
T4749 8061-8069 VB denotes remained
T4750 8070-8074 JJ denotes high
T4751 8075-8078 IN denotes for
T4752 8079-8081 IN denotes at
T4753 8082-8087 JJ denotes least
T4754 8088-8090 CD denotes 48
T4755 8091-8096 NN denotes hours
T4756 8097-8098 -LRB- denotes (
T4757 8098-8104 NN denotes Figure
T4758 8105-8106 CD denotes 5
T4759 8106-8107 -RRB- denotes )
T4760 8109-8110 DT denotes A
T4761 8111-8118 JJ denotes similar
T4762 8119-8134 NN denotes phosphorylation
T4763 8135-8138 VB denotes was
T4764 8139-8147 VB denotes observed
T4765 8148-8150 IN denotes in
T4766 8151-8156 NN denotes Ramos
T4767 8157-8162 NN denotes cells
T4768 8162-8163 -COMMA- denotes ,
T4769 8164-8167 CC denotes but
T4770 8168-8171 RB denotes not
T4771 8172-8174 IN denotes in
T4772 8175-8179 NN denotes HL60
T4773 8180-8185 NN denotes cells
T4774 8186-8187 -LRB- denotes (
T4775 8187-8193 NN denotes Figure
T4776 8194-8195 CD denotes 6
T4777 8195-8196 -RRB- denotes )
T4778 8198-8209 RB denotes Furthermore
T4779 8209-8210 -COMMA- denotes ,
T4780 8211-8213 PRP denotes we
T4781 8214-8218 RB denotes also
T4782 8219-8225 VB denotes tested
T4783 8226-8233 IN denotes whether
T4784 8234-8239 JJ denotes other
T4785 8240-8245 VB denotes known
T4786 8246-8256 JJ denotes downstream
T4787 8257-8267 NN denotes signalling
T4788 8268-8276 NN denotes pathways
T4789 8277-8279 IN denotes of
T4790 8280-8285 NN denotes BMP-6
T4791 8286-8291 MD denotes could
T4792 8292-8294 VB denotes be
T4793 8295-8304 VB denotes triggered
T4794 8305-8307 IN denotes by
T4795 8308-8313 NN denotes BMP-6
T4796 8314-8316 IN denotes in
T4797 8317-8322 JJ denotes human
T4798 8323-8324 NN denotes B
T4799 8325-8330 NN denotes cells
T4800 8332-8339 RB denotes However
T4801 8339-8340 -COMMA- denotes ,
T4802 8341-8343 PRP denotes we
T4803 8344-8347 VB denotes did
T4804 8348-8351 RB denotes not
T4805 8352-8359 VB denotes observe
T4806 8360-8363 DT denotes any
T4807 8364-8375 JJ denotes significant
T4808 8376-8383 NN denotes changes
T4809 8384-8386 IN denotes in
T4810 8387-8390 DT denotes the
T4811 8391-8396 NN denotes level
T4812 8397-8399 IN denotes of
T4813 8400-8413 NN denotes phospho-STAT3
T4814 8414-8416 CC denotes or
T4815 8417-8428 NN denotes phospho-p38
T4816 8429-8433 IN denotes upon
T4817 8434-8439 NN denotes BMP-6
T4818 8440-8449 NN denotes treatment
T4819 8450-8452 IN denotes of
T4820 8453-8454 NN denotes B
T4821 8455-8460 NN denotes cells
T4822 8461-8462 -LRB- denotes (
T4823 8462-8466 NN denotes data
T4824 8467-8470 RB denotes not
T4825 8471-8476 VB denotes shown
T4826 8476-8477 -RRB- denotes )
T5461 8480-8485 NN denotes BMP-6
T5462 8486-8493 VB denotes induces
T5463 8494-8506 NN denotes upregulation
T5464 8507-8509 IN denotes of
T5465 8510-8513 NN denotes Id1
T5466 8514-8518 RB denotes Next
T5467 8518-8519 -COMMA- denotes ,
T5468 8520-8522 PRP denotes we
T5469 8523-8529 VB denotes wanted
T5470 8530-8532 TO denotes to
T5471 8533-8540 VB denotes explore
T5472 8541-8548 IN denotes whether
T5473 8549-8552 DT denotes the
T5474 8553-8558 NN denotes BMP-6
T5475 8559-8566 VB denotes induced
T5476 8567-8582 NN denotes phosphorylation
T5477 8583-8585 IN denotes of
T5478 8586-8590 NN denotes Smad
T5479 8591-8596 CD denotes 1/5/8
T5480 8597-8601 RB denotes also
T5481 8602-8607 MD denotes could
T5482 8608-8614 VB denotes induce
T5483 8615-8630 JJ denotes transcriptional
T5484 8631-8638 NN denotes changes
T5485 8639-8641 IN denotes of
T5486 8642-8648 NN denotes target
T5487 8649-8654 NN denotes genes
T5488 8656-8658 IN denotes In
T5489 8659-8663 DT denotes this
T5490 8664-8670 NN denotes regard
T5491 8670-8671 -COMMA- denotes ,
T5492 8672-8675 DT denotes the
T5493 8676-8686 NN denotes inhibitors
T5494 8687-8689 IN denotes of
T5495 8690-8693 NN denotes DNA
T5496 8694-8701 NN denotes binding
T5497 8702-8710 NN denotes proteins
T5498 8711-8712 -LRB- denotes (
T5499 8712-8715 NN denotes Ids
T5500 8715-8716 -RRB- denotes )
T5501 8717-8720 VB denotes are
T5502 8721-8731 VB denotes considered
T5503 8732-8734 TO denotes to
T5504 8735-8737 VB denotes be
T5505 8738-8742 DT denotes some
T5506 8743-8745 IN denotes of
T5507 8746-8749 DT denotes the
T5508 8750-8755 JJ denotes major
T5509 8756-8762 NN denotes target
T5510 8763-8768 NN denotes genes
T5511 8769-8772 IN denotes for
T5512 8773-8788 JJ denotes Smad-signalling
T5513 8789-8790 -LRB- denotes [
T5514 8790-8792 CD denotes 17
T5515 8792-8793 -RRB- denotes ]
T5516 8795-8799 RB denotes Thus
T5517 8799-8800 -COMMA- denotes ,
T5518 8801-8802 NN denotes B
T5519 8803-8808 NN denotes cells
T5520 8809-8813 VB denotes were
T5521 8814-8827 JJ denotes pre-incubated
T5522 8828-8832 IN denotes over
T5523 8833-8838 NN denotes night
T5524 8839-8841 IN denotes in
T5525 8842-8848 NN denotes X-VIVO
T5526 8849-8851 CD denotes 15
T5527 8851-8852 -COMMA- denotes ,
T5528 8853-8856 CC denotes and
T5529 8857-8861 RB denotes then
T5530 8862-8870 VB denotes cultured
T5531 8871-8873 IN denotes in
T5532 8874-8880 NN denotes medium
T5533 8881-8886 RB denotes alone
T5534 8887-8889 CC denotes or
T5535 8890-8892 IN denotes in
T5536 8893-8896 DT denotes the
T5537 8897-8905 NN denotes presence
T5538 8906-8908 IN denotes of
T5539 8909-8914 NN denotes BMP-6
T5540 8915-8918 IN denotes for
T5541 8919-8926 JJ denotes various
T5542 8927-8931 NN denotes time
T5543 8932-8938 NN denotes points
T5544 8939-8945 IN denotes before
T5545 8946-8957 NN denotes preparation
T5546 8958-8960 IN denotes of
T5547 8961-8966 JJ denotes total
T5548 8967-8970 NN denotes RNA
T5549 8972-8975 DT denotes The
T5550 8976-8982 NN denotes amount
T5551 8983-8985 IN denotes of
T5552 8986-8993 NN denotes Id1–Id4
T5553 8994-8998 NN denotes mRNA
T5554 8999-9002 VB denotes was
T5555 9003-9013 VB denotes quantified
T5556 9014-9016 IN denotes by
T5557 9017-9026 JJ denotes real-time
T5558 9027-9033 NN denotes RT-PCR
T5559 9035-9048 RB denotes Interestingly
T5560 9048-9049 -COMMA- denotes ,
T5561 9050-9052 PRP denotes we
T5562 9053-9061 VB denotes observed
T5563 9062-9063 DT denotes a
T5564 9064-9072 JJ denotes specific
T5565 9073-9082 JJ denotes four-fold
T5566 9083-9095 NN denotes upregulation
T5567 9096-9098 IN denotes of
T5568 9099-9102 NN denotes Id1
T5569 9103-9107 NN denotes mRNA
T5570 9108-9110 IN denotes in
T5571 9111-9124 JJ denotes BMP-6-treated
T5572 9125-9126 NN denotes B
T5573 9127-9132 NN denotes cells
T5574 9133-9134 -LRB- denotes (
T5575 9134-9140 NN denotes Figure
T5576 9141-9142 CD denotes 7
T5577 9142-9143 -RRB- denotes )
T5578 9145-9148 DT denotes The
T5579 9149-9162 NN denotes up-regulation
T5580 9163-9165 IN denotes of
T5581 9166-9169 NN denotes Id1
T5582 9170-9174 NN denotes mRNA
T5583 9175-9178 VB denotes was
T5584 9179-9193 JJ denotes characteristic
T5585 9194-9196 IN denotes of
T5586 9197-9199 DT denotes an
T5587 9200-9205 JJ denotes early
T5588 9206-9215 JJ denotes inducible
T5589 9216-9220 NN denotes gene
T5590 9220-9221 -COMMA- denotes ,
T5591 9222-9226 IN denotes with
T5592 9227-9234 JJ denotes maximal
T5593 9235-9247 NN denotes upregulation
T5594 9248-9251 CD denotes two
T5595 9252-9257 NN denotes hours
T5596 9258-9263 IN denotes after
T5597 9264-9267 DT denotes the
T5598 9268-9276 NN denotes addition
T5599 9277-9279 IN denotes of
T5600 9280-9285 NN denotes BMP-6
T5601 9286-9289 CC denotes and
T5602 9290-9298 VB denotes returned
T5603 9299-9301 TO denotes to
T5604 9302-9310 NN denotes baseline
T5605 9311-9316 IN denotes after
T5606 9317-9319 CD denotes 24
T5607 9320-9325 NN denotes hours
T5608 9327-9329 IN denotes In
T5609 9330-9338 NN denotes contrast
T5610 9338-9339 -COMMA- denotes ,
T5611 9340-9342 DT denotes no
T5612 9343-9354 JJ denotes significant
T5613 9355-9362 NN denotes changes
T5614 9363-9367 VB denotes were
T5615 9368-9376 VB denotes observed
T5616 9377-9380 IN denotes for
T5617 9381-9384 NN denotes Id2
T5618 9385-9388 CC denotes and
T5619 9389-9392 NN denotes Id3
T5620 9393-9397 NN denotes mRNA
T5621 9397-9398 -COMMA- denotes ,
T5622 9399-9406 IN denotes whereas
T5623 9407-9422 NN denotes Id4-transcripts
T5624 9423-9427 VB denotes were
T5625 9428-9431 RB denotes not
T5626 9432-9442 JJ denotes detectable
T5627 9443-9444 -LRB- denotes (
T5628 9444-9450 NN denotes Figure
T5629 9451-9452 CD denotes 7
T5630 9452-9453 -COMMA- denotes ,
T5631 9454-9458 NN denotes data
T5632 9459-9462 RB denotes not
T5633 9463-9468 VB denotes shown
T5634 9468-9469 -RRB- denotes )
T5635 9471-9478 NN denotes Western
T5636 9479-9483 NN denotes blot
T5637 9484-9492 NN denotes analysis
T5638 9493-9501 VB denotes revealed
T5639 9502-9506 IN denotes that
T5640 9507-9510 DT denotes the
T5641 9511-9524 JJ denotes BMP-6-induced
T5642 9525-9537 NN denotes upregulation
T5643 9538-9540 IN denotes of
T5644 9541-9544 NN denotes Id1
T5645 9545-9549 NN denotes mRNA
T5646 9550-9554 RB denotes also
T5647 9555-9558 VB denotes was
T5648 9559-9569 VB denotes correlated
T5649 9570-9574 IN denotes with
T5650 9575-9587 NN denotes upregulation
T5651 9588-9590 IN denotes of
T5652 9591-9594 NN denotes Id1
T5653 9595-9602 NN denotes protein
T5654 9603-9605 RB denotes as
T5655 9606-9610 RB denotes well
T5656 9612-9615 DT denotes The
T5657 9616-9624 NN denotes increase
T5658 9625-9627 IN denotes in
T5659 9628-9631 NN denotes Id1
T5660 9632-9639 NN denotes protein
T5661 9640-9645 NN denotes level
T5662 9646-9649 VB denotes was
T5663 9650-9660 JJ denotes detectable
T5664 9661-9666 IN denotes after
T5665 9667-9670 CD denotes one
T5666 9671-9675 NN denotes hour
T5667 9676-9679 CC denotes and
T5668 9680-9689 VB denotes increased
T5669 9690-9695 IN denotes until
T5670 9696-9698 CD denotes 24
T5671 9699-9704 NN denotes hours
T5672 9705-9710 IN denotes after
T5673 9711-9716 NN denotes BMP-6
T5674 9717-9725 NN denotes addition
T5675 9725-9726 -COMMA- denotes ,
T5676 9727-9734 VB denotes showing
T5677 9735-9736 DT denotes a
T5678 9737-9744 JJ denotes 16-fold
T5679 9745-9757 NN denotes upregulation
T5680 9758-9766 VB denotes compared
T5681 9767-9771 IN denotes with
T5682 9772-9774 NN denotes t0
T5683 9775-9776 -LRB- denotes (
T5684 9776-9777 NN denotes p
T5685 9778-9779 NN denotes ≤
T5686 9780-9785 CD denotes 0.020
T5687 9785-9786 -COMMA- denotes ,
T5688 9787-9788 NN denotes n
T5689 9789-9790 SYM denotes =
T5690 9791-9792 CD denotes 4
T5691 9792-9793 -RRB- denotes )
T5692 9794-9795 -LRB- denotes (
T5693 9795-9801 NN denotes Figure
T5694 9802-9803 CD denotes 8
T5695 9804-9807 CC denotes and
T5696 9808-9809 CD denotes 9
T5697 9809-9810 -RRB- denotes )
T5698 9812-9814 IN denotes In
T5699 9815-9819 NN denotes line
T5700 9820-9824 IN denotes with
T5701 9825-9828 DT denotes the
T5702 9829-9833 NN denotes mRNA
T5703 9834-9838 NN denotes data
T5704 9838-9839 -COMMA- denotes ,
T5705 9840-9842 DT denotes no
T5706 9843-9853 JJ denotes consistent
T5707 9854-9860 NN denotes change
T5708 9861-9863 IN denotes in
T5709 9864-9867 DT denotes the
T5710 9868-9875 NN denotes amounts
T5711 9876-9878 IN denotes of
T5712 9879-9882 NN denotes Id2
T5713 9883-9886 CC denotes and
T5714 9887-9890 NN denotes Id3
T5715 9891-9898 NN denotes protein
T5716 9899-9904 MD denotes could
T5717 9905-9907 VB denotes be
T5718 9908-9916 VB denotes observed
T5719 9917-9918 -LRB- denotes (
T5720 9918-9924 NN denotes Figure
T5721 9925-9926 CD denotes 8
T5722 9927-9930 CC denotes and
T5723 9931-9932 CD denotes 9
T5724 9932-9933 -RRB- denotes )
T5725 9935-9937 PRP denotes We
T5726 9938-9942 VB denotes were
T5727 9943-9947 JJ denotes able
T5728 9948-9950 TO denotes to
T5729 9951-9956 VB denotes block
T5730 9957-9960 DT denotes the
T5731 9961-9964 NN denotes Id1
T5732 9965-9973 JJ denotes specific
T5733 9974-9978 NN denotes band
T5734 9979-9983 IN denotes with
T5735 9984-9985 DT denotes a
T5736 9986-9994 VB denotes blocking
T5737 9995-10002 NN denotes peptide
T5738 10003-10004 -LRB- denotes (
T5739 10004-10008 NN denotes data
T5740 10009-10012 RB denotes not
T5741 10013-10018 VB denotes shown
T5742 10018-10019 -RRB- denotes )
T5743 10021-10026 VB denotes Taken
T5744 10027-10035 RB denotes together
T5745 10035-10036 -COMMA- denotes ,
T5746 10037-10042 DT denotes these
T5747 10043-10047 NN denotes data
T5748 10048-10055 VB denotes suggest
T5749 10056-10060 IN denotes that
T5750 10061-10064 NN denotes Id1
T5751 10065-10070 MD denotes could
T5752 10071-10073 VB denotes be
T5753 10074-10075 DT denotes a
T5754 10076-10084 JJ denotes possible
T5755 10085-10091 NN denotes target
T5756 10092-10096 NN denotes gene
T5757 10097-10100 IN denotes for
T5758 10101-10110 VB denotes mediating
T5759 10111-10114 DT denotes the
T5760 10115-10122 NN denotes effects
T5761 10123-10125 IN denotes of
T5762 10126-10131 NN denotes BMP-6
T5763 10132-10134 IN denotes in
T5764 10135-10140 JJ denotes human
T5765 10141-10142 NN denotes B
T5766 10143-10148 NN denotes cells
T5767 10148-10149 -COMMA- denotes ,
T5768 10150-10157 IN denotes whereas
T5769 10158-10161 NN denotes Id2
T5770 10162-10165 CC denotes and
T5771 10166-10169 NN denotes Id3
T5772 10170-10173 RB denotes not
T5773 10174-10178 VB denotes seem
T5774 10179-10181 TO denotes to
T5775 10182-10184 VB denotes be
T5776 10185-10193 VB denotes involved
T6493 10196-10201 NN denotes BMP-6
T6494 10202-10212 NN denotes production
T6495 10213-10215 IN denotes in
T6496 10216-10217 NN denotes B
T6497 10218-10223 NN denotes cells
T6498 10224-10227 DT denotes The
T6499 10228-10232 NN denotes fact
T6500 10233-10237 IN denotes that
T6501 10238-10243 NN denotes BMP-6
T6502 10244-10247 VB denotes has
T6503 10248-10252 VB denotes been
T6504 10253-10261 VB denotes reported
T6505 10262-10264 TO denotes to
T6506 10265-10268 VB denotes act
T6507 10269-10271 IN denotes as
T6508 10272-10274 DT denotes an
T6509 10275-10284 JJ denotes autocrine
T6510 10285-10295 NN denotes stimulator
T6511 10296-10298 IN denotes in
T6512 10299-10311 NN denotes chondrocytes
T6513 10312-10313 -LRB- denotes [
T6514 10313-10315 CD denotes 18
T6515 10315-10316 -RRB- denotes ]
T6516 10317-10320 CC denotes and
T6517 10321-10328 NN denotes ovarium
T6518 10329-10330 -LRB- denotes [
T6519 10330-10332 CD denotes 19
T6520 10332-10333 -RRB- denotes ]
T6521 10333-10334 -COMMA- denotes ,
T6522 10335-10343 VB denotes prompted
T6523 10344-10346 PRP denotes us
T6524 10347-10349 TO denotes to
T6525 10350-10361 VB denotes investigate
T6526 10362-10369 IN denotes whether
T6527 10370-10376 JJ denotes normal
T6528 10377-10382 JJ denotes human
T6529 10383-10384 NN denotes B
T6530 10385-10390 NN denotes cells
T6531 10391-10396 MD denotes could
T6532 10397-10404 VB denotes produce
T6533 10405-10410 NN denotes BMP-6
T6534 10411-10415 IN denotes upon
T6535 10416-10427 NN denotes stimulation
T6536 10429-10434 NN denotes Ramos
T6537 10435-10440 NN denotes cells
T6538 10440-10441 -COMMA- denotes ,
T6539 10442-10447 WDT denotes which
T6540 10448-10452 VB denotes have
T6541 10453-10457 VB denotes been
T6542 10458-10467 VB denotes described
T6543 10468-10470 TO denotes to
T6544 10471-10478 VB denotes express
T6545 10479-10484 NN denotes BMP-6
T6546 10485-10489 NN denotes mRNA
T6547 10490-10502 RB denotes endogenously
T6548 10503-10504 -LRB- denotes [
T6549 10504-10506 CD denotes 20
T6550 10506-10507 -RRB- denotes ]
T6551 10507-10508 -COMMA- denotes ,
T6552 10509-10512 CC denotes and
T6553 10513-10516 DT denotes the
T6554 10517-10518 NN denotes T
T6555 10519-10523 NN denotes cell
T6556 10524-10528 NN denotes line
T6557 10529-10535 NN denotes Jurkat
T6558 10535-10536 -COMMA- denotes ,
T6559 10537-10543 VB denotes served
T6560 10544-10546 IN denotes as
T6561 10547-10555 JJ denotes positive
T6562 10556-10559 CC denotes and
T6563 10560-10568 JJ denotes negative
T6564 10569-10577 NN denotes controls
T6565 10577-10578 -COMMA- denotes ,
T6566 10579-10591 RB denotes respectively
T6567 10593-10603 JJ denotes Endogenous
T6568 10604-10609 NN denotes BMP-6
T6569 10610-10614 NN denotes mRNA
T6570 10615-10621 NN denotes levels
T6571 10622-10624 IN denotes in
T6572 10625-10631 JJ denotes normal
T6573 10632-10633 NN denotes B
T6574 10634-10639 NN denotes cells
T6575 10640-10644 VB denotes were
T6576 10645-10655 VB denotes quantified
T6577 10656-10658 IN denotes by
T6578 10659-10668 JJ denotes real-time
T6579 10669-10675 NN denotes RT-PCR
T6580 10676-10681 IN denotes after
T6581 10682-10693 NN denotes stimulation
T6582 10694-10698 IN denotes with
T6583 10699-10707 NN denotes anti-IgM
T6584 10708-10711 IN denotes for
T6585 10712-10721 JJ denotes different
T6586 10722-10726 NN denotes time
T6587 10727-10733 NN denotes points
T6588 10735-10748 RB denotes Interestingly
T6589 10748-10749 -COMMA- denotes ,
T6590 10750-10753 DT denotes the
T6591 10754-10767 NN denotes up-regulation
T6592 10768-10770 IN denotes of
T6593 10771-10776 NN denotes BMP-6
T6594 10777-10781 NN denotes mRNA
T6595 10782-10785 VB denotes was
T6596 10786-10800 JJ denotes characteristic
T6597 10801-10803 IN denotes of
T6598 10804-10806 DT denotes an
T6599 10807-10815 JJ denotes early-to
T6600 10816-10828 JJ denotes intermediate
T6601 10829-10838 JJ denotes inducible
T6602 10839-10843 NN denotes gene
T6603 10844-10848 IN denotes with
T6604 10849-10856 JJ denotes maximal
T6605 10857-10869 NN denotes upregulation
T6606 10870-10874 CD denotes four
T6607 10875-10880 NN denotes hours
T6608 10881-10886 IN denotes after
T6609 10887-10890 DT denotes the
T6610 10891-10899 NN denotes addition
T6611 10900-10902 IN denotes of
T6612 10903-10911 NN denotes anti-IgM
T6613 10913-10916 DT denotes The
T6614 10917-10922 NN denotes level
T6615 10923-10925 IN denotes of
T6616 10926-10931 NN denotes BMP-6
T6617 10932-10936 NN denotes mRNA
T6618 10937-10940 VB denotes was
T6619 10941-10945 RB denotes back
T6620 10946-10948 TO denotes to
T6621 10949-10957 NN denotes baseline
T6622 10958-10963 IN denotes after
T6623 10964-10966 CD denotes 24
T6624 10967-10972 NN denotes hours
T6625 10973-10977 IN denotes upon
T6626 10978-10989 NN denotes stimulation
T6627 10990-10991 -LRB- denotes (
T6628 10991-10997 NN denotes Figure
T6629 10998-11000 CD denotes 10
T6630 11000-11001 -RRB- denotes )
T6631 11003-11014 RB denotes Furthermore
T6632 11014-11015 -COMMA- denotes ,
T6633 11016-11020 CC denotes both
T6634 11021-11024 NN denotes FCS
T6635 11025-11028 CC denotes and
T6636 11029-11034 JJ denotes human
T6637 11035-11043 NN denotes AB-serum
T6638 11044-11051 VB denotes induced
T6639 11052-11063 JJ denotes significant
T6640 11064-11076 NN denotes upregulation
T6641 11077-11079 IN denotes of
T6642 11080-11085 NN denotes BMP-6
T6643 11086-11090 NN denotes mRNA
T6644 11091-11092 -LRB- denotes (
T6645 11092-11098 NN denotes Figure
T6646 11099-11101 CD denotes 11
T6647 11101-11102 -RRB- denotes )
T6648 11104-11117 RB denotes Interestingly
T6649 11117-11118 -COMMA- denotes ,
T6650 11119-11121 IN denotes in
T6651 11122-11123 DT denotes a
T6652 11124-11132 JJ denotes separate
T6653 11133-11138 NN denotes study
T6654 11139-11141 PRP denotes we
T6655 11142-11146 VB denotes have
T6656 11147-11152 VB denotes found
T6657 11153-11157 IN denotes that
T6658 11158-11164 JJ denotes normal
T6659 11165-11170 JJ denotes human
T6660 11171-11172 NN denotes T
T6661 11173-11178 NN denotes cells
T6662 11179-11181 VB denotes do
T6663 11182-11185 RB denotes not
T6664 11186-11193 VB denotes express
T6665 11194-11199 NN denotes BMP-6
T6666 11200-11204 NN denotes mRNA
T6667 11205-11210 IN denotes after
T6668 11211-11221 NN denotes activation
T6669 11222-11223 -LRB- denotes (
T6670 11223-11232 NNP denotes Sivertsen
T6671 11233-11235 FW denotes et
T6672 11236-11238 FW denotes al
T6673 11238-11239 -COMMA- denotes ,
T6674 11240-11250 NN denotes manuscript
T6675 11251-11253 IN denotes in
T6676 11254-11265 NN denotes preparation
T6677 11265-11266 -RRB- denotes )
T6678 11268-11272 RB denotes Next
T6679 11272-11273 -COMMA- denotes ,
T6680 11274-11276 PRP denotes we
T6681 11277-11283 VB denotes wanted
T6682 11284-11286 TO denotes to
T6683 11287-11293 VB denotes detect
T6684 11294-11299 NN denotes BMP-6
T6685 11300-11307 NN denotes protein
T6686 11308-11310 IN denotes in
T6687 11311-11317 JJ denotes normal
T6688 11318-11325 NN denotes B-cells
T6689 11326-11329 CC denotes and
T6690 11330-11336 VB denotes tested
T6691 11337-11344 JJ denotes various
T6692 11345-11357 RB denotes commercially
T6693 11358-11367 JJ denotes available
T6694 11368-11378 NN denotes antibodies
T6695 11380-11387 RB denotes However
T6696 11387-11388 -COMMA- denotes ,
T6697 11389-11391 IN denotes in
T6698 11392-11395 PRP-DOLLAR- denotes our
T6699 11396-11401 NN denotes hands
T6700 11402-11407 DT denotes these
T6701 11408-11418 JJ denotes anti-BMP-6
T6702 11419-11429 NN denotes antibodies
T6703 11430-11433 VB denotes did
T6704 11434-11438 RB denotes only
T6705 11439-11448 VB denotes recognize
T6706 11449-11452 DT denotes the
T6707 11453-11464 JJ denotes recombinant
T6708 11465-11470 NN denotes BMP-6
T6709 11471-11478 NN denotes protein
T6710 11479-11482 CC denotes and
T6711 11483-11486 RB denotes not
T6712 11487-11490 DT denotes the
T6713 11491-11497 JJ denotes native
T6714 11498-11505 NN denotes protein
T7965 11519-11525 JJ denotes Recent
T7966 11526-11533 NN denotes studies
T7967 11534-11538 VB denotes have
T7968 11539-11551 VB denotes demonstrated
T7969 11552-11554 DT denotes an
T7970 11555-11564 JJ denotes important
T7971 11565-11569 NN denotes role
T7972 11570-11573 IN denotes for
T7973 11574-11577 NN denotes BMP
T7974 11578-11589 NN denotes superfamily
T7975 11590-11597 NN denotes members
T7976 11598-11600 IN denotes in
T7977 11601-11614 JJ denotes hematopoietic
T7978 11615-11619 NN denotes stem
T7979 11620-11625 NN denotes cells
T7980 11625-11626 -COMMA- denotes ,
T7981 11627-11632 JJ denotes early
T7982 11633-11643 NN denotes thymocytes
T7983 11644-11645 -LRB- denotes [
T7984 11645-11648 CD denotes 6,7
T7985 11648-11649 -RRB- denotes ]
T7986 11650-11653 CC denotes and
T7987 11654-11660 NN denotes B-cell
T7988 11661-11673 NN denotes malignancies
T7989 11674-11675 -LRB- denotes [
T7990 11675-11682 CD denotes 8,11,12
T7991 11682-11683 -RRB- denotes ]
T7992 11683-11684 -COMMA- denotes ,
T7993 11685-11688 CC denotes but
T7994 11689-11690 DT denotes a
T7995 11691-11695 NN denotes role
T7996 11696-11699 IN denotes for
T7997 11700-11704 NN denotes BMPs
T7998 11705-11707 IN denotes in
T7999 11708-11714 JJ denotes normal
T8000 11715-11720 JJ denotes human
T8001 11721-11722 NN denotes B
T8002 11723-11728 NN denotes cells
T8003 11729-11732 VB denotes has
T8004 11733-11743 RB denotes previously
T8005 11744-11747 RB denotes not
T8006 11748-11752 VB denotes been
T8007 11753-11761 VB denotes reported
T8008 11763-11766 DT denotes The
T8009 11767-11774 JJ denotes present
T8010 11775-11780 NN denotes study
T8011 11781-11793 VB denotes demonstrated
T8012 11794-11795 DT denotes a
T8013 11796-11807 JJ denotes significant
T8014 11808-11825 JJ denotes antiproliferative
T8015 11826-11832 NN denotes effect
T8016 11833-11835 IN denotes of
T8017 11836-11841 NN denotes BMP-6
T8018 11842-11844 IN denotes in
T8019 11845-11855 JJ denotes peripheral
T8020 11856-11861 NN denotes blood
T8021 11862-11867 JJ denotes CD19+
T8022 11868-11869 NN denotes B
T8023 11870-11875 NN denotes cells
T8024 11877-11889 RB denotes Additionally
T8025 11889-11890 -COMMA- denotes ,
T8026 11891-11896 NN denotes BMP-6
T8027 11897-11904 VB denotes induced
T8028 11905-11909 NN denotes cell
T8029 11910-11915 NN denotes death
T8030 11916-11918 IN denotes in
T8031 11919-11924 JJ denotes CD27+
T8032 11925-11931 NN denotes memory
T8033 11932-11933 NN denotes B
T8034 11934-11939 NN denotes cells
T8035 11940-11942 RB denotes as
T8036 11943-11947 RB denotes well
T8037 11948-11950 IN denotes as
T8038 11951-11953 IN denotes in
T8039 11954-11955 DT denotes a
T8040 11956-11963 NN denotes Burkitt
T8041 11964-11972 NN denotes lymphoma
T8042 11973-11977 NN denotes cell
T8043 11978-11982 NN denotes line
T8044 11983-11984 -LRB- denotes (
T8045 11984-11989 NN denotes Ramos
T8046 11989-11990 -RRB- denotes )
T8047 11992-12003 RB denotes Importantly
T8048 12003-12004 -COMMA- denotes ,
T8049 12005-12010 NN denotes BMP-6
T8050 12011-12018 VB denotes induced
T8051 12019-12020 DT denotes a
T8052 12021-12026 JJ denotes rapid
T8053 12027-12030 CC denotes and
T8054 12031-12037 JJ denotes marked
T8055 12038-12046 NN denotes increase
T8056 12047-12049 IN denotes in
T8057 12050-12060 NN denotes Smad-1/5/8
T8058 12061-12076 NN denotes phosphorylation
T8059 12078-12089 RB denotes Furthermore
T8060 12089-12090 -COMMA- denotes ,
T8061 12091-12094 DT denotes the
T8062 12095-12100 NN denotes BMP-6
T8063 12101-12108 VB denotes induced
T8064 12109-12113 NN denotes Smad
T8065 12114-12129 NN denotes phosphorylation
T8066 12130-12133 VB denotes was
T8067 12134-12142 VB denotes followed
T8068 12143-12145 IN denotes by
T8069 12146-12147 DT denotes a
T8070 12148-12157 JJ denotes selective
T8071 12158-12170 NN denotes upregulation
T8072 12171-12173 IN denotes of
T8073 12174-12177 NN denotes Id1
T8074 12178-12182 NN denotes mRNA
T8075 12183-12186 CC denotes and
T8076 12187-12197 JJ denotes subsequent
T8077 12198-12201 NN denotes Id1
T8078 12202-12209 NN denotes protein
T8079 12211-12213 IN denotes In
T8080 12214-12217 DT denotes the
T8081 12218-12225 JJ denotes present
T8082 12226-12231 NN denotes study
T8083 12231-12232 -COMMA- denotes ,
T8084 12233-12236 DT denotes the
T8085 12237-12249 VB denotes demonstrated
T8086 12250-12267 JJ denotes antiproliferative
T8087 12268-12274 NN denotes effect
T8088 12275-12277 IN denotes of
T8089 12278-12283 NN denotes BMP-6
T8090 12284-12286 IN denotes in
T8091 12287-12295 JJ denotes anti-IgM
T8092 12296-12303 VB denotes treated
T8093 12304-12305 NN denotes B
T8094 12306-12311 NN denotes cells
T8095 12312-12315 VB denotes was
T8096 12316-12327 JJ denotes significant
T8097 12328-12331 CC denotes and
T8098 12332-12346 JJ denotes dose-dependent
T8099 12348-12359 RB denotes Importantly
T8100 12359-12360 -COMMA- denotes ,
T8101 12361-12364 DT denotes the
T8102 12365-12383 JJ denotes anti-proliferative
T8103 12384-12390 NN denotes effect
T8104 12391-12393 IN denotes of
T8105 12394-12399 NN denotes BMP-6
T8106 12400-12405 MD denotes could
T8107 12406-12408 VB denotes be
T8108 12409-12419 RB denotes completely
T8109 12420-12431 VB denotes neutralized
T8110 12432-12434 IN denotes by
T8111 12435-12438 DT denotes the
T8112 12439-12442 NN denotes use
T8113 12443-12445 IN denotes of
T8114 12446-12447 DT denotes a
T8115 12448-12455 JJ denotes natural
T8116 12456-12465 NN denotes inhibitor
T8117 12465-12466 -COMMA- denotes ,
T8118 12467-12474 NNP denotes Noggin.
T8119 12475-12479 DT denotes This
T8120 12480-12482 VB denotes is
T8121 12483-12485 IN denotes in
T8122 12486-12490 NN denotes line
T8123 12491-12495 IN denotes with
T8124 12496-12502 NN denotes others
T8125 12502-12503 -COMMA- denotes ,
T8126 12504-12511 VB denotes showing
T8127 12512-12516 IN denotes that
T8128 12517-12523 NN denotes Noggin
T8129 12524-12527 MD denotes can
T8130 12528-12536 VB denotes function
T8131 12537-12539 IN denotes as
T8132 12540-12541 DT denotes a
T8133 12542-12547 JJ denotes BMP-6
T8134 12548-12558 NN denotes antagonist
T8135 12559-12560 -LRB- denotes [
T8136 12560-12565 CD denotes 21,22
T8137 12565-12566 -RRB- denotes ]
T8138 12568-12570 IN denotes In
T8139 12571-12579 NN denotes addition
T8140 12579-12580 -COMMA- denotes ,
T8141 12581-12584 DT denotes the
T8142 12585-12596 NN denotes combination
T8143 12597-12599 IN denotes of
T8144 12600-12607 JJ denotes soluble
T8145 12608-12618 NN denotes BMP-RIB-Fc
T8146 12619-12622 CC denotes and
T8147 12623-12633 NN denotes BMP-RII-Fc
T8148 12634-12640 NN denotes fusion
T8149 12641-12649 NN denotes proteins
T8150 12650-12654 RB denotes also
T8151 12655-12666 VB denotes neutralized
T8152 12667-12670 DT denotes the
T8153 12671-12689 JJ denotes anti-proliferative
T8154 12690-12696 NN denotes effect
T8155 12697-12699 IN denotes of
T8156 12700-12705 NN denotes BMP-6
T8157 12706-12708 IN denotes in
T8158 12709-12714 JJ denotes human
T8159 12715-12716 NN denotes B
T8160 12717-12722 NN denotes cells
T8161 12724-12737 RB denotes Interestingly
T8162 12737-12738 -COMMA- denotes ,
T8163 12739-12741 IN denotes as
T8164 12742-12745 IN denotes for
T8165 12746-12751 JJ denotes other
T8166 12752-12755 NN denotes TGF
T8167 12756-12762 NN denotes family
T8168 12763-12770 NN denotes members
T8169 12770-12771 -COMMA- denotes ,
T8170 12772-12784 JJ denotes bifunctional
T8171 12785-12792 NN denotes effects
T8172 12793-12797 VB denotes have
T8173 12798-12802 RB denotes also
T8174 12803-12807 VB denotes been
T8175 12808-12820 VB denotes demonstrated
T8176 12821-12824 IN denotes for
T8177 12825-12829 NN denotes BMPs
T8178 12831-12838 IN denotes Whereas
T8179 12839-12846 JJ denotes several
T8180 12847-12849 IN denotes of
T8181 12850-12853 DT denotes the
T8182 12854-12858 NN denotes BMPs
T8183 12859-12863 VB denotes have
T8184 12864-12868 VB denotes been
T8185 12869-12874 VB denotes shown
T8186 12875-12877 TO denotes to
T8187 12878-12885 VB denotes promote
T8188 12886-12899 NN denotes proliferation
T8189 12900-12902 IN denotes in
T8190 12903-12910 JJ denotes various
T8191 12911-12915 NN denotes cell
T8192 12916-12921 NN denotes types
T8193 12922-12931 VB denotes including
T8194 12932-12943 NN denotes condrocytes
T8195 12944-12945 -LRB- denotes [
T8196 12945-12947 CD denotes 23
T8197 12947-12948 -RRB- denotes ]
T8198 12948-12949 -COMMA- denotes ,
T8199 12950-12955 NN denotes liver
T8200 12956-12957 -LRB- denotes [
T8201 12957-12959 CD denotes 24
T8202 12959-12960 -RRB- denotes ]
T8203 12961-12964 CC denotes and
T8204 12965-12974 NN denotes granulosa
T8205 12975-12980 NN denotes cells
T8206 12981-12982 -LRB- denotes [
T8207 12982-12984 CD denotes 25
T8208 12984-12985 -RRB- denotes ]
T8209 12985-12986 -COMMA- denotes ,
T8210 12987-13004 JJ denotes antiproliferative
T8211 13005-13012 NN denotes effects
T8212 13013-13016 CC denotes and
T8213 13017-13026 NN denotes induction
T8214 13027-13029 IN denotes of
T8215 13030-13039 NN denotes apoptosis
T8216 13040-13043 VB denotes has
T8217 13044-13048 VB denotes been
T8218 13049-13057 VB denotes reported
T8219 13058-13061 IN denotes for
T8220 13062-13063 NN denotes B
T8221 13064-13067 CC denotes and
T8222 13068-13069 NN denotes T
T8223 13070-13077 NN denotes lineage
T8224 13078-13083 NN denotes cells
T8225 13085-13092 JJ denotes Similar
T8226 13093-13100 NN denotes effects
T8227 13101-13103 IN denotes as
T8228 13104-13116 VB denotes demonstrated
T8229 13117-13120 IN denotes for
T8230 13121-13126 NN denotes BMP-6
T8231 13127-13129 IN denotes on
T8232 13130-13135 JJ denotes human
T8233 13136-13137 NN denotes B
T8234 13138-13143 NN denotes cells
T8235 13144-13146 IN denotes in
T8236 13147-13150 DT denotes the
T8237 13151-13158 JJ denotes present
T8238 13159-13164 NN denotes study
T8239 13164-13165 -COMMA- denotes ,
T8240 13166-13170 VB denotes were
T8241 13171-13183 VB denotes demonstrated
T8242 13184-13187 IN denotes for
T8243 13188-13193 NN denotes BMP-2
T8244 13193-13194 -COMMA- denotes ,
T8245 13195-13196 CD denotes 4
T8246 13196-13197 -COMMA- denotes ,
T8247 13198-13199 CD denotes 6
T8248 13200-13203 CC denotes and
T8249 13204-13206 CD denotes -7
T8250 13207-13209 IN denotes in
T8251 13210-13215 JJ denotes human
T8252 13216-13223 NN denotes myeloma
T8253 13224-13229 NN denotes cells
T8254 13230-13231 -LRB- denotes [
T8255 13231-13235 CD denotes 9-11
T8256 13235-13236 -RRB- denotes ]
T8257 13238-13243 JJ denotes Other
T8258 13244-13251 NN denotes members
T8259 13252-13254 IN denotes of
T8260 13255-13258 DT denotes the
T8261 13259-13269 NN denotes BMP-family
T8262 13270-13274 VB denotes have
T8263 13275-13279 RB denotes also
T8264 13280-13284 VB denotes been
T8265 13285-13293 VB denotes reported
T8266 13294-13296 TO denotes to
T8267 13297-13303 VB denotes induce
T8268 13304-13313 NN denotes apoptosis
T8269 13313-13314 -COMMA- denotes ,
T8270 13315-13324 VB denotes including
T8271 13325-13327 IN denotes in
T8272 13328-13333 NN denotes mouse
T8273 13334-13335 NN denotes B
T8274 13336-13343 NN denotes lineage
T8275 13344-13349 NN denotes cells
T8276 13350-13351 -LRB- denotes [
T8277 13351-13353 CD denotes 26
T8278 13353-13354 -RRB- denotes ]
T8279 13356-13368 RB denotes Additionally
T8280 13368-13369 -COMMA- denotes ,
T8281 13370-13375 NN denotes BMP-4
T8282 13376-13384 VB denotes inhibits
T8283 13385-13394 NN denotes thymocyte
T8284 13395-13408 NN denotes proliferation
T8285 13409-13410 -LRB- denotes [
T8286 13410-13411 CD denotes 6
T8287 13411-13412 -RRB- denotes ]
T8288 13414-13419 VB denotes Taken
T8289 13420-13428 RB denotes together
T8290 13428-13429 -COMMA- denotes ,
T8291 13430-13435 DT denotes these
T8292 13436-13440 NN denotes data
T8293 13441-13448 VB denotes suggest
T8294 13449-13453 IN denotes that
T8295 13454-13457 DT denotes the
T8296 13458-13462 NN denotes role
T8297 13463-13465 IN denotes of
T8298 13466-13470 NN denotes BMPs
T8299 13471-13473 IN denotes in
T8300 13474-13477 DT denotes the
T8301 13478-13488 NN denotes regulation
T8302 13489-13491 IN denotes of
T8303 13492-13505 NN denotes proliferation
T8304 13506-13509 CC denotes and
T8305 13510-13519 NN denotes apoptosis
T8306 13520-13522 VB denotes is
T8307 13523-13529 RB denotes highly
T8308 13530-13534 NN denotes cell
T8309 13535-13539 NN denotes type
T8310 13540-13549 JJ denotes dependent
T8311 13551-13553 TO denotes To
T8312 13554-13561 VB denotes examine
T8313 13562-13565 WRB denotes how
T8314 13566-13571 NN denotes BMP-6
T8315 13572-13578 VB denotes exerts
T8316 13579-13582 PRP-DOLLAR- denotes its
T8317 13583-13593 JJ denotes functional
T8318 13594-13601 NN denotes effects
T8319 13602-13604 IN denotes in
T8320 13605-13606 NN denotes B
T8321 13607-13612 NN denotes cells
T8322 13612-13613 -COMMA- denotes ,
T8323 13614-13616 PRP denotes we
T8324 13617-13625 VB denotes analysed
T8325 13626-13629 NN denotes BMP
T8326 13630-13638 NN denotes receptor
T8327 13639-13649 NN denotes expression
T8328 13650-13652 IN denotes by
T8329 13653-13660 JJ denotes western
T8330 13661-13665 NN denotes blot
T8331 13666-13674 NN denotes analysis
T8332 13676-13681 JJ denotes Human
T8333 13682-13692 JJ denotes peripheral
T8334 13693-13694 NN denotes B
T8335 13695-13700 NN denotes cells
T8336 13701-13705 VB denotes were
T8337 13706-13711 VB denotes found
T8338 13712-13714 TO denotes to
T8339 13715-13722 VB denotes express
T8340 13723-13726 DT denotes the
T8341 13727-13730 NN denotes BMP
T8342 13731-13735 NN denotes type
T8343 13736-13737 CD denotes I
T8344 13738-13747 NN denotes receptors
T8345 13748-13755 NN denotes Act-RIA
T8346 13756-13759 CC denotes and
T8347 13760-13767 NN denotes BMP-RIB
T8348 13767-13768 -COMMA- denotes ,
T8349 13769-13772 CC denotes and
T8350 13773-13776 DT denotes the
T8351 13777-13781 NN denotes type
T8352 13782-13794 NN denotes II-receptors
T8353 13795-13802 NN denotes BMP-RII
T8354 13803-13806 CC denotes and
T8355 13807-13815 NN denotes Act-RIIb
T8356 13815-13816 -COMMA- denotes ,
T8357 13817-13822 WDT denotes which
T8358 13823-13829 VB denotes signal
T8359 13830-13835 IN denotes after
T8360 13836-13843 NN denotes binding
T8361 13844-13846 IN denotes of
T8362 13847-13854 JJ denotes several
T8363 13855-13859 NN denotes BMPs
T8364 13859-13860 -COMMA- denotes ,
T8365 13861-13870 VB denotes including
T8366 13871-13876 NN denotes BMP-6
T8367 13877-13878 -LRB- denotes [
T8368 13878-13883 CD denotes 16,13
T8369 13883-13884 -RRB- denotes ]
T8370 13886-13888 TO denotes To
T8371 13889-13896 RB denotes further
T8372 13897-13904 VB denotes explore
T8373 13905-13910 NN denotes BMP-6
T8374 13911-13918 VB denotes induced
T8375 13919-13929 NN denotes signalling
T8376 13929-13930 -COMMA- denotes ,
T8377 13931-13941 NN denotes activation
T8378 13942-13944 IN denotes of
T8379 13945-13952 JJ denotes several
T8380 13953-13961 NN denotes pathways
T8381 13962-13964 VB denotes is
T8382 13965-13973 JJ denotes possible
T8383 13975-13978 DT denotes The
T8384 13979-13984 JJ denotes major
T8385 13985-13995 NN denotes signalling
T8386 13996-14003 NN denotes pathway
T8387 14004-14009 VB denotes known
T8388 14010-14012 TO denotes to
T8389 14013-14017 NN denotes date
T8390 14017-14018 -COMMA- denotes ,
T8391 14019-14021 VB denotes is
T8392 14022-14032 NN denotes activation
T8393 14033-14035 IN denotes of
T8394 14036-14043 NN denotes R-Smads
T8395 14044-14045 -LRB- denotes [
T8396 14045-14050 CD denotes 13,27
T8397 14050-14051 -RRB- denotes ]
T8398 14053-14055 IN denotes In
T8399 14056-14060 DT denotes that
T8400 14061-14068 NN denotes respect
T8401 14068-14069 -COMMA- denotes ,
T8402 14070-14074 NN denotes BMPs
T8403 14075-14079 VB denotes have
T8404 14080-14084 VB denotes been
T8405 14085-14090 VB denotes shown
T8406 14091-14093 TO denotes to
T8407 14094-14099 VB denotes exert
T8408 14100-14117 JJ denotes antiproliferative
T8409 14118-14125 NN denotes effects
T8410 14126-14128 IN denotes in
T8411 14129-14130 NN denotes B
T8412 14131-14138 NN denotes lineage
T8413 14139-14144 NN denotes cells
T8414 14145-14148 IN denotes via
T8415 14149-14164 NN denotes phosphorylation
T8416 14165-14167 IN denotes of
T8417 14168-14174 NN denotes R-Smad
T8418 14175-14176 -LRB- denotes [
T8419 14176-14181 CD denotes 11,28
T8420 14181-14182 -RRB- denotes ]
T8421 14184-14195 RB denotes Furthermore
T8422 14195-14196 -COMMA- denotes ,
T8423 14197-14202 NN denotes BMP-2
T8424 14203-14206 VB denotes has
T8425 14207-14211 VB denotes been
T8426 14212-14217 VB denotes shown
T8427 14218-14220 TO denotes to
T8428 14221-14227 VB denotes induce
T8429 14228-14238 NN denotes activation
T8430 14239-14241 IN denotes of
T8431 14242-14247 NN denotes STAT3
T8432 14248-14250 IN denotes in
T8433 14251-14258 NN denotes myeloma
T8434 14259-14264 NN denotes cells
T8435 14265-14266 -LRB- denotes [
T8436 14266-14267 CD denotes 9
T8437 14267-14268 -RRB- denotes ]
T8438 14270-14277 RB denotes However
T8439 14277-14278 -COMMA- denotes ,
T8440 14279-14294 NN denotes phosphorylation
T8441 14295-14297 IN denotes of
T8442 14298-14304 NN denotes R-Smad
T8443 14305-14308 VB denotes was
T8444 14309-14312 RB denotes not
T8445 14313-14325 VB denotes investigated
T8446 14326-14328 IN denotes in
T8447 14329-14333 DT denotes that
T8448 14334-14339 NN denotes study
T8449 14341-14346 NN denotes BMP-2
T8450 14347-14350 VB denotes has
T8451 14351-14355 RB denotes also
T8452 14356-14360 VB denotes been
T8453 14361-14366 VB denotes shown
T8454 14367-14369 TO denotes to
T8455 14370-14376 VB denotes induce
T8456 14377-14392 NN denotes phosphorylation
T8457 14393-14395 IN denotes of
T8458 14396-14399 NN denotes p38
T8459 14400-14401 -LRB- denotes [
T8460 14401-14403 CD denotes 29
T8461 14403-14404 -RRB- denotes ]
T8462 14406-14410 RB denotes Thus
T8463 14410-14411 -COMMA- denotes ,
T8464 14412-14427 NN denotes phosphorylation
T8465 14428-14430 IN denotes of
T8466 14431-14434 NN denotes p38
T8467 14434-14435 -COMMA- denotes ,
T8468 14436-14441 NN denotes STAT3
T8469 14442-14445 CC denotes and
T8470 14446-14455 NN denotes Smad1/5/8
T8471 14456-14465 VB denotes represent
T8472 14466-14475 JJ denotes important
T8473 14476-14490 JJ denotes BMP-signalling
T8474 14491-14499 NN denotes pathways
T8475 14500-14504 WDT denotes that
T8476 14505-14513 VB denotes mediated
T8477 14514-14517 DT denotes the
T8478 14518-14525 NN denotes effects
T8479 14526-14528 IN denotes of
T8480 14529-14533 NN denotes BMPs
T8481 14534-14537 CC denotes and
T8482 14538-14542 RB denotes even
T8483 14543-14553 JJ denotes cross-talk
T8484 14554-14561 IN denotes between
T8485 14562-14567 DT denotes these
T8486 14568-14576 NN denotes pathways
T8487 14577-14580 VB denotes has
T8488 14581-14585 VB denotes been
T8489 14586-14594 VB denotes reported
T8490 14595-14596 -LRB- denotes [
T8491 14596-14601 CD denotes 29,30
T8492 14601-14602 -RRB- denotes ]
T8493 14604-14606 IN denotes In
T8494 14607-14610 DT denotes the
T8495 14611-14618 JJ denotes present
T8496 14619-14624 NN denotes study
T8497 14624-14625 -COMMA- denotes ,
T8498 14626-14628 PRP denotes we
T8499 14629-14633 VB denotes were
T8500 14634-14637 RB denotes not
T8501 14638-14642 JJ denotes able
T8502 14643-14645 TO denotes to
T8503 14646-14652 VB denotes detect
T8504 14653-14666 JJ denotes BMP-6-induced
T8505 14667-14674 NN denotes changes
T8506 14675-14677 IN denotes in
T8507 14678-14681 DT denotes the
T8508 14682-14697 NN denotes phosphorylation
T8509 14698-14704 NN denotes status
T8510 14705-14707 IN denotes of
T8511 14708-14713 NN denotes STAT3
T8512 14714-14716 CC denotes or
T8513 14717-14720 NN denotes p38
T8514 14721-14723 IN denotes in
T8515 14724-14729 JJ denotes human
T8516 14730-14740 JJ denotes peripheral
T8517 14741-14742 NN denotes B
T8518 14743-14748 NN denotes cells
T8519 14750-14757 RB denotes Instead
T8520 14757-14758 -COMMA- denotes ,
T8521 14759-14760 DT denotes a
T8522 14761-14766 JJ denotes rapid
T8523 14767-14770 CC denotes and
T8524 14771-14777 JJ denotes marked
T8525 14778-14793 NN denotes phosphorylation
T8526 14794-14796 IN denotes of
T8527 14797-14806 NN denotes Smad1/5/8
T8528 14807-14810 VB denotes was
T8529 14811-14819 VB denotes revealed
T8530 14821-14823 IN denotes In
T8531 14824-14825 DT denotes a
T8532 14826-14834 JJ denotes parallel
T8533 14835-14840 NN denotes study
T8534 14840-14841 -COMMA- denotes ,
T8535 14842-14844 PRP denotes we
T8536 14845-14849 VB denotes have
T8537 14850-14855 VB denotes found
T8538 14856-14860 IN denotes that
T8539 14861-14866 JJ denotes other
T8540 14867-14871 NN denotes BMPs
T8541 14872-14876 RB denotes also
T8542 14877-14884 VB denotes induced
T8543 14885-14900 NN denotes phosphorylation
T8544 14901-14903 IN denotes of
T8545 14904-14913 NN denotes Smad1/5/8
T8546 14914-14916 IN denotes in
T8547 14917-14927 JJ denotes peripheral
T8548 14928-14929 NN denotes B
T8549 14930-14935 NN denotes cells
T8550 14936-14937 -LRB- denotes (
T8551 14937-14941 NN denotes data
T8552 14942-14945 RB denotes not
T8553 14946-14951 VB denotes shown
T8554 14951-14952 -RRB- denotes )
T8555 14954-14956 PRP denotes We
T8556 14957-14960 VB denotes are
T8557 14961-14970 RB denotes currently
T8558 14971-14979 VB denotes pursuing
T8559 14980-14990 NN denotes microarray
T8560 14991-14998 NN denotes studies
T8561 14999-15001 TO denotes to
T8562 15002-15010 VB denotes identify
T8563 15011-15014 DT denotes the
T8564 15015-15025 NN denotes signalling
T8565 15026-15034 NN denotes pathways
T8566 15035-15038 CC denotes and
T8567 15039-15045 NN denotes target
T8568 15046-15051 NN denotes genes
T8569 15052-15056 WDT denotes that
T8570 15057-15060 VB denotes are
T8571 15061-15072 RB denotes differently
T8572 15073-15082 VB denotes regulated
T8573 15083-15085 IN denotes by
T8574 15086-15089 DT denotes the
T8575 15090-15097 JJ denotes various
T8576 15098-15102 NN denotes BMPs
T8577 15103-15105 IN denotes in
T8578 15106-15111 JJ denotes human
T8579 15112-15113 NN denotes B
T8580 15114-15119 NN denotes cells
T8581 15121-15133 NN denotes Upregulation
T8582 15134-15136 IN denotes of
T8583 15137-15140 NN denotes Id1
T8584 15141-15144 IN denotes via
T8585 15145-15154 NN denotes Smad1/5/8
T8586 15155-15170 NN denotes phosphorylation
T8587 15171-15173 VB denotes is
T8588 15174-15175 DT denotes a
T8589 15176-15181 JJ denotes known
T8590 15182-15191 NN denotes mechanism
T8591 15192-15195 IN denotes for
T8592 15196-15201 NN denotes BMP-6
T8593 15202-15212 NN denotes signalling
T8594 15213-15215 IN denotes in
T8595 15216-15221 JJ denotes other
T8596 15222-15226 NN denotes cell
T8597 15227-15234 NN denotes systems
T8598 15235-15236 -LRB- denotes [
T8599 15236-15241 CD denotes 31,32
T8600 15241-15242 -RRB- denotes ]
T8601 15243-15246 CC denotes and
T8602 15247-15257 NN denotes regulation
T8603 15258-15260 IN denotes of
T8604 15261-15272 NN denotes Id-proteins
T8605 15273-15275 VB denotes is
T8606 15276-15283 VB denotes thought
T8607 15284-15286 TO denotes to
T8608 15287-15289 VB denotes be
T8609 15290-15292 DT denotes an
T8610 15293-15302 JJ denotes important
T8611 15303-15312 NN denotes mechanism
T8612 15313-15316 IN denotes for
T8613 15317-15332 NN denotes Smad-signalling
T8614 15333-15334 -LRB- denotes [
T8615 15334-15336 CD denotes 17
T8616 15336-15337 -RRB- denotes ]
T8617 15339-15341 IN denotes In
T8618 15342-15345 DT denotes the
T8619 15346-15353 JJ denotes present
T8620 15354-15359 NN denotes study
T8621 15359-15360 -COMMA- denotes ,
T8622 15361-15370 JJ denotes real-time
T8623 15371-15377 NN denotes RT-PCR
T8624 15378-15389 NN denotes experiments
T8625 15390-15398 VB denotes revealed
T8626 15399-15400 DT denotes a
T8627 15401-15409 JJ denotes specific
T8628 15410-15419 JJ denotes four-fold
T8629 15420-15432 NN denotes upregulation
T8630 15433-15436 IN denotes for
T8631 15437-15440 NN denotes Id1
T8632 15441-15443 IN denotes in
T8633 15444-15457 JJ denotes BMP-6-treated
T8634 15458-15459 NN denotes B
T8635 15460-15465 NN denotes cells
T8636 15465-15466 -COMMA- denotes ,
T8637 15467-15472 IN denotes while
T8638 15473-15476 DT denotes the
T8639 15477-15483 NN denotes amount
T8640 15484-15486 IN denotes of
T8641 15487-15494 NN denotes Id2–Id4
T8642 15495-15503 VB denotes remained
T8643 15504-15513 JJ denotes unchanged
T8644 15515-15517 IN denotes In
T8645 15518-15527 NN denotes agreement
T8646 15528-15532 IN denotes with
T8647 15533-15537 DT denotes this
T8648 15537-15538 -COMMA- denotes ,
T8649 15539-15546 JJ denotes western
T8650 15547-15551 NN denotes blot
T8651 15552-15560 NN denotes analysis
T8652 15561-15573 VB denotes demonstrated
T8653 15574-15576 DT denotes an
T8654 15577-15589 NN denotes upregulation
T8655 15590-15592 IN denotes of
T8656 15593-15596 NN denotes Id1
T8657 15597-15604 NN denotes protein
T8658 15604-15605 -COMMA- denotes ,
T8659 15606-15611 IN denotes while
T8660 15612-15615 DT denotes the
T8661 15616-15622 NN denotes amount
T8662 15623-15625 IN denotes of
T8663 15626-15629 NN denotes Id2
T8664 15630-15633 CC denotes and
T8665 15634-15637 NN denotes Id3
T8666 15638-15645 NN denotes protein
T8667 15646-15652 NN denotes levels
T8668 15653-15661 VB denotes remained
T8669 15662-15671 JJ denotes unchanged
T8670 15673-15683 RB denotes Previously
T8671 15683-15684 -COMMA- denotes ,
T8672 15685-15688 NN denotes Id1
T8673 15689-15692 VB denotes has
T8674 15693-15697 VB denotes been
T8675 15698-15708 VB denotes considered
T8676 15709-15712 RB denotes not
T8677 15713-15715 TO denotes to
T8678 15716-15718 VB denotes be
T8679 15719-15728 VB denotes expressed
T8680 15729-15731 IN denotes in
T8681 15732-15737 JJ denotes later
T8682 15738-15751 JJ denotes developmental
T8683 15752-15758 NN denotes stages
T8684 15759-15763 IN denotes than
T8685 15764-15769 JJ denotes pro-B
T8686 15770-15775 NN denotes cells
T8687 15776-15777 -LRB- denotes [
T8688 15777-15782 CD denotes 33,34
T8689 15782-15783 -RRB- denotes ]
T8690 15783-15784 -COMMA- denotes ,
T8691 15785-15788 CC denotes and
T8692 15789-15792 PRP-DOLLAR- denotes its
T8693 15793-15805 JJ denotes constitutive
T8694 15806-15816 NN denotes expression
T8695 15817-15820 VB denotes has
T8696 15821-15825 VB denotes been
T8697 15826-15834 VB denotes reported
T8698 15835-15837 TO denotes to
T8699 15838-15844 VB denotes impair
T8700 15845-15850 NN denotes mouse
T8701 15851-15852 NN denotes B
T8702 15853-15857 NN denotes cell
T8703 15858-15869 NN denotes development
T8704 15870-15871 -LRB- denotes [
T8705 15871-15873 CD denotes 35
T8706 15873-15874 -RRB- denotes ]
T8707 15876-15885 RB denotes Therefore
T8708 15885-15886 -COMMA- denotes ,
T8709 15887-15890 PRP-DOLLAR- denotes our
T8710 15891-15904 NN denotes demonstration
T8711 15905-15907 IN denotes of
T8712 15908-15911 DT denotes the
T8713 15912-15926 JJ denotes time-dependent
T8714 15927-15939 NN denotes upregulation
T8715 15940-15942 IN denotes of
T8716 15943-15946 NN denotes Id1
T8717 15947-15951 NN denotes mRNA
T8718 15952-15955 CC denotes and
T8719 15956-15963 NN denotes protein
T8720 15964-15966 IN denotes in
T8721 15967-15973 JJ denotes mature
T8722 15974-15980 JJ denotes normal
T8723 15981-15986 JJ denotes human
T8724 15987-15988 NN denotes B
T8725 15989-15994 NN denotes cells
T8726 15995-15997 VB denotes is
T8727 15998-16000 IN denotes of
T8728 16001-16011 JJ denotes particular
T8729 16012-16020 NN denotes interest
T8730 16022-16024 IN denotes In
T8731 16025-16029 DT denotes that
T8732 16030-16037 NN denotes respect
T8733 16037-16038 -COMMA- denotes ,
T8734 16039-16041 PRP denotes it
T8735 16042-16044 VB denotes is
T8736 16045-16055 JJ denotes noteworthy
T8737 16056-16060 IN denotes that
T8738 16061-16066 NN denotes TGF-β
T8739 16067-16077 NN denotes signalling
T8740 16078-16080 IN denotes in
T8741 16081-16086 JJ denotes early
T8742 16087-16090 CC denotes and
T8743 16091-16097 JJ denotes mature
T8744 16098-16099 NN denotes B
T8745 16100-16105 NN denotes cells
T8746 16106-16113 VB denotes induces
T8747 16114-16118 CC denotes both
T8748 16119-16122 NN denotes Id2
T8749 16123-16126 CC denotes and
T8750 16127-16130 NN denotes Id3
T8751 16131-16141 NN denotes expression
T8752 16142-16143 -LRB- denotes [
T8753 16143-16148 CD denotes 36,37
T8754 16148-16149 -RRB- denotes ]
T8755 16149-16150 -COMMA- denotes ,
T8756 16151-16154 CC denotes but
T8757 16155-16158 RB denotes not
T8758 16159-16162 NN denotes Id1
T8759 16163-16164 -LRB- denotes (
T8760 16164-16168 NN denotes data
T8761 16169-16172 RB denotes not
T8762 16173-16178 VB denotes shown
T8763 16178-16179 -RRB- denotes )
T8764 16181-16194 RB denotes Interestingly
T8765 16194-16195 -COMMA- denotes ,
T8766 16196-16201 DT denotes these
T8767 16202-16209 NN denotes results
T8768 16210-16214 VB denotes show
T8769 16215-16219 IN denotes that
T8770 16220-16227 JJ denotes various
T8771 16228-16235 NN denotes members
T8772 16236-16238 IN denotes of
T8773 16239-16242 DT denotes the
T8774 16243-16248 NN denotes TGF-β
T8775 16249-16255 NN denotes family
T8776 16256-16264 VB denotes regulate
T8777 16265-16267 NN denotes Id
T8778 16268-16276 NN denotes proteins
T8779 16277-16288 RB denotes differently
T8780 16290-16293 NN denotes Id2
T8781 16294-16297 CC denotes and
T8782 16298-16301 NN denotes Id3
T8783 16302-16305 VB denotes are
T8784 16306-16316 VB denotes considered
T8785 16317-16319 TO denotes to
T8786 16320-16322 VB denotes be
T8787 16323-16326 DT denotes the
T8788 16327-16329 NN denotes Id
T8789 16330-16338 NN denotes proteins
T8790 16339-16345 RB denotes mainly
T8791 16346-16355 VB denotes expressed
T8792 16356-16358 IN denotes in
T8793 16359-16365 JJ denotes mature
T8794 16366-16367 NN denotes B
T8795 16368-16373 NN denotes cells
T8796 16374-16375 -LRB- denotes [
T8797 16375-16377 CD denotes 38
T8798 16377-16378 -RRB- denotes ]
T8799 16380-16383 DT denotes The
T8800 16384-16391 JJ denotes present
T8801 16392-16397 NN denotes study
T8802 16398-16402 RB denotes also
T8803 16403-16408 VB denotes found
T8804 16409-16412 NN denotes Id2
T8805 16413-16416 CC denotes and
T8806 16417-16420 NN denotes Id3
T8807 16421-16428 NN denotes protein
T8808 16429-16431 IN denotes in
T8809 16432-16433 NN denotes B
T8810 16434-16439 NN denotes cells
T8811 16440-16442 TO denotes to
T8812 16443-16445 VB denotes be
T8813 16446-16450 RB denotes more
T8814 16451-16457 RB denotes highly
T8815 16458-16467 VB denotes expressed
T8816 16468-16472 IN denotes than
T8817 16473-16476 NN denotes Id1
T8818 16477-16479 IN denotes in
T8819 16480-16487 VB denotes resting
T8820 16488-16489 NN denotes B
T8821 16490-16495 NN denotes cells
T8822 16497-16504 RB denotes However
T8823 16504-16505 -COMMA- denotes ,
T8824 16506-16511 NN denotes BMP-6
T8825 16512-16515 VB denotes did
T8826 16516-16519 RB denotes not
T8827 16520-16526 VB denotes induce
T8828 16527-16538 JJ denotes significant
T8829 16539-16546 NN denotes changes
T8830 16547-16549 IN denotes in
T8831 16550-16553 DT denotes the
T8832 16554-16561 NN denotes protein
T8833 16562-16572 NN denotes expression
T8834 16573-16575 IN denotes of
T8835 16576-16579 NN denotes Id2
T8836 16580-16583 CC denotes and
T8837 16584-16587 NN denotes Id3
T8838 16589-16591 PRP denotes It
T8839 16592-16594 VB denotes is
T8840 16595-16603 VB denotes believed
T8841 16604-16608 IN denotes that
T8842 16609-16611 NN denotes Id
T8843 16612-16620 NN denotes proteins
T8844 16621-16626 VB denotes block
T8845 16627-16642 NN denotes differentiation
T8846 16643-16646 CC denotes and
T8847 16647-16654 VB denotes promote
T8848 16655-16668 NN denotes proliferation
T8849 16669-16671 IN denotes in
T8850 16672-16679 JJ denotes various
T8851 16680-16684 NN denotes cell
T8852 16685-16690 NN denotes types
T8853 16691-16692 -LRB- denotes [
T8854 16692-16697 CD denotes 39,33
T8855 16697-16698 -RRB- denotes ]
T8856 16700-16702 NN denotes Id
T8857 16703-16711 NN denotes proteins
T8858 16712-16715 VB denotes act
T8859 16716-16718 IN denotes as
T8860 16719-16736 JJ denotes dominant-negative
T8861 16737-16747 NN denotes inhibitors
T8862 16748-16750 IN denotes of
T8863 16751-16761 NN denotes E-proteins
T8864 16762-16765 CC denotes and
T8865 16766-16770 NN denotes Pax5
T8866 16771-16779 NN denotes function
T8867 16780-16782 IN denotes by
T8868 16783-16790 VB denotes forming
T8869 16791-16797 NN denotes dimers
T8870 16798-16802 IN denotes with
T8871 16803-16808 DT denotes these
T8872 16809-16817 NN denotes proteins
T8873 16817-16818 -COMMA- denotes ,
T8874 16819-16825 VB denotes making
T8875 16826-16830 PRP denotes them
T8876 16831-16837 JJ denotes unable
T8877 16838-16840 TO denotes to
T8878 16841-16845 VB denotes bind
T8879 16846-16849 NN denotes DNA
T8880 16851-16853 PRP denotes It
T8881 16854-16857 VB denotes has
T8882 16858-16862 VB denotes been
T8883 16863-16871 VB denotes proposed
T8884 16872-16876 IN denotes that
T8885 16877-16880 DT denotes the
T8886 16881-16888 NN denotes balance
T8887 16889-16894 IN denotes among
T8888 16895-16905 NN denotes E-proteins
T8889 16905-16906 -COMMA- denotes ,
T8890 16907-16911 NN denotes Pax5
T8891 16912-16915 CC denotes and
T8892 16916-16918 NN denotes Id
T8893 16919-16927 NN denotes proteins
T8894 16928-16933 MD denotes might
T8895 16934-16938 VB denotes have
T8896 16939-16941 DT denotes an
T8897 16942-16951 JJ denotes important
T8898 16952-16956 NN denotes role
T8899 16957-16959 IN denotes in
T8900 16960-16969 VB denotes activated
T8901 16970-16971 NN denotes B
T8902 16972-16977 NN denotes cells
T8903 16978-16979 -LRB- denotes [
T8904 16979-16981 CD denotes 38
T8905 16981-16982 -RRB- denotes ]
T8906 16984-16986 IN denotes In
T8907 16987-16991 DT denotes that
T8908 16992-16999 NN denotes respect
T8909 16999-17000 -COMMA- denotes ,
T8910 17001-17011 NN denotes E-proteins
T8911 17012-17016 VB denotes have
T8912 17017-17021 VB denotes been
T8913 17022-17032 VB denotes implicated
T8914 17033-17035 IN denotes in
T8915 17036-17040 CC denotes both
T8916 17041-17044 DT denotes the
T8917 17045-17054 NN denotes promotion
T8918 17055-17058 CC denotes and
T8919 17059-17069 NN denotes inhibition
T8920 17070-17072 IN denotes of
T8921 17073-17077 NN denotes cell
T8922 17078-17086 NN denotes survival
T8923 17087-17090 CC denotes and
T8924 17091-17097 NN denotes growth
T8925 17098-17100 IN denotes at
T8926 17101-17110 JJ denotes different
T8927 17111-17117 NN denotes points
T8928 17118-17120 IN denotes in
T8929 17121-17131 NN denotes lymphocyte
T8930 17132-17143 NN denotes development
T8931 17144-17145 -LRB- denotes [
T8932 17145-17147 CD denotes 40
T8933 17147-17148 -RRB- denotes ]
T8934 17150-17153 DT denotes The
T8935 17154-17171 JJ denotes antiproliferative
T8936 17172-17175 CC denotes and
T8937 17176-17181 NN denotes death
T8938 17182-17190 VB denotes inducing
T8939 17191-17197 NN denotes effect
T8940 17198-17200 IN denotes of
T8941 17201-17206 NN denotes BMP-6
T8942 17207-17209 IN denotes in
T8943 17210-17211 NN denotes B
T8944 17212-17217 NN denotes cells
T8945 17218-17222 IN denotes with
T8946 17223-17234 JJ denotes concomitant
T8947 17235-17247 NN denotes upregulation
T8948 17248-17250 IN denotes of
T8949 17251-17254 NN denotes Id1
T8950 17255-17262 NN denotes protein
T8951 17263-17265 VB denotes is
T8952 17266-17275 RB denotes therefore
T8953 17276-17278 IN denotes in
T8954 17279-17283 NN denotes line
T8955 17284-17288 IN denotes with
T8956 17289-17292 DT denotes the
T8957 17293-17297 NN denotes view
T8958 17298-17302 IN denotes that
T8959 17303-17305 NN denotes Id
T8960 17306-17314 NN denotes proteins
T8961 17315-17318 VB denotes are
T8962 17319-17327 VB denotes required
T8963 17328-17331 IN denotes for
T8964 17332-17335 DT denotes the
T8965 17336-17345 NN denotes induction
T8966 17346-17348 IN denotes of
T8967 17349-17355 NN denotes growth
T8968 17356-17362 NN denotes arrest
T8969 17363-17366 CC denotes and
T8970 17367-17376 NN denotes apoptosis
T8971 17377-17379 IN denotes in
T8972 17380-17392 NN denotes B-lymphocyte
T8973 17393-17404 NN denotes progenitors
T8974 17405-17407 IN denotes by
T8975 17408-17413 NN denotes TGF-β
T8976 17414-17415 -LRB- denotes [
T8977 17415-17417 CD denotes 40
T8978 17417-17418 -RRB- denotes ]
T8979 17420-17431 RB denotes Furthermore
T8980 17431-17432 -COMMA- denotes ,
T8981 17433-17435 NN denotes Id
T8982 17436-17444 NN denotes proteins
T8983 17445-17448 VB denotes are
T8984 17449-17454 VB denotes known
T8985 17455-17457 IN denotes as
T8986 17458-17467 JJ denotes important
T8987 17468-17473 NN denotes parts
T8988 17474-17476 IN denotes of
T8989 17477-17487 NN denotes signalling
T8990 17488-17496 NN denotes pathways
T8991 17497-17505 VB denotes involved
T8992 17506-17508 IN denotes in
T8993 17509-17520 NN denotes development
T8994 17520-17521 -COMMA- denotes ,
T8995 17522-17526 NN denotes cell
T8996 17527-17532 NN denotes cycle
T8997 17533-17536 CC denotes and
T8998 17537-17550 NN denotes tumorigenesis
T8999 17551-17552 -LRB- denotes [
T9000 17552-17554 CD denotes 32
T9001 17554-17555 -RRB- denotes ]
T9002 17557-17559 PRP denotes It
T9003 17560-17562 VB denotes is
T9004 17563-17567 RB denotes well
T9005 17568-17579 VB denotes established
T9006 17580-17584 IN denotes that
T9007 17585-17592 JJ denotes various
T9008 17593-17600 NN denotes members
T9009 17601-17603 IN denotes of
T9010 17604-17607 DT denotes the
T9011 17608-17610 NN denotes Id
T9012 17611-17617 NN denotes family
T9013 17618-17621 VB denotes are
T9014 17622-17635 VB denotes overexpressed
T9015 17636-17638 IN denotes in
T9016 17639-17640 DT denotes a
T9017 17641-17646 NN denotes range
T9018 17647-17649 IN denotes of
T9019 17650-17655 JJ denotes human
T9020 17656-17663 NN denotes tumours
T9021 17664-17667 CC denotes and
T9022 17668-17677 RB denotes generally
T9023 17677-17678 -COMMA- denotes ,
T9024 17679-17682 NN denotes Id1
T9025 17683-17690 VB denotes appears
T9026 17691-17693 TO denotes to
T9027 17694-17696 VB denotes be
T9028 17697-17700 DT denotes the
T9029 17701-17707 NN denotes family
T9030 17708-17714 NN denotes member
T9031 17715-17719 RB denotes most
T9032 17720-17726 RB denotes widely
T9033 17727-17740 VB denotes overexpressed
T9034 17741-17743 IN denotes in
T9035 17744-17745 DT denotes a
T9036 17746-17753 NN denotes variety
T9037 17754-17756 IN denotes of
T9038 17757-17762 JJ denotes human
T9039 17763-17775 NN denotes malignancies
T9040 17776-17777 -LRB- denotes [
T9041 17777-17779 CD denotes 41
T9042 17779-17780 -RRB- denotes ]
T9043 17780-17781 -COMMA- denotes ,
T9044 17782-17791 VB denotes including
T9045 17792-17800 JJ denotes multiple
T9046 17801-17808 NN denotes myeloma
T9047 17809-17810 -LRB- denotes [
T9048 17810-17815 CD denotes 42,32
T9049 17815-17816 -RRB- denotes ]
T9050 17818-17830 RB denotes Additionally
T9051 17830-17831 -COMMA- denotes ,
T9052 17832-17835 PRP-DOLLAR- denotes our
T9053 17836-17844 NN denotes findings
T9054 17845-17849 IN denotes that
T9055 17850-17855 NN denotes BMP-6
T9056 17856-17865 VB denotes activates
T9057 17866-17879 JJ denotes intracellular
T9058 17880-17890 NN denotes signalling
T9059 17891-17899 NN denotes pathways
T9060 17900-17902 IN denotes in
T9061 17903-17908 JJ denotes human
T9062 17909-17910 NN denotes B
T9063 17911-17916 NN denotes cells
T9064 17917-17922 MD denotes might
T9065 17923-17925 VB denotes be
T9066 17926-17928 IN denotes of
T9067 17929-17938 JJ denotes potential
T9068 17939-17957 JJ denotes pathophysiological
T9069 17958-17970 NN denotes significance
T9070 17971-17973 IN denotes in
T9071 17974-17982 NN denotes lymphoma
T9072 17983-17986 CC denotes and
T9073 17987-17999 NN denotes inflammation
T9074 18001-18005 JJ denotes High
T9075 18006-18011 NN denotes BMP-6
T9076 18012-18016 NN denotes mRNA
T9077 18017-18027 NN denotes expression
T9078 18028-18030 IN denotes in
T9079 18031-18036 NN denotes DLBCL
T9080 18037-18040 VB denotes has
T9081 18041-18045 VB denotes been
T9082 18046-18051 VB denotes shown
T9083 18052-18054 TO denotes to
T9084 18055-18064 VB denotes correlate
T9085 18065-18067 TO denotes to
T9086 18068-18080 JJ denotes unfavourable
T9087 18081-18088 NN denotes outcome
T9088 18089-18090 -LRB- denotes [
T9089 18090-18092 CD denotes 12
T9090 18092-18093 -RRB- denotes ]
T9091 18095-18097 IN denotes In
T9092 18098-18102 DT denotes this
T9093 18103-18110 NN denotes respect
T9094 18110-18111 -COMMA- denotes ,
T9095 18112-18114 PRP denotes it
T9096 18115-18117 VB denotes is
T9097 18118-18120 IN denotes of
T9098 18121-18129 NN denotes interest
T9099 18130-18134 WDT denotes that
T9100 18135-18143 VB denotes targeted
T9101 18144-18154 NN denotes expression
T9102 18155-18157 IN denotes of
T9103 18158-18161 NN denotes Id1
T9104 18162-18164 TO denotes to
T9105 18165-18178 NN denotes B-lymphocytes
T9106 18179-18187 VB denotes resulted
T9107 18188-18190 IN denotes in
T9108 18191-18199 JJ denotes aberrant
T9109 18200-18201 NN denotes B
T9110 18202-18206 NN denotes cell
T9111 18207-18218 NN denotes development
T9112 18218-18219 -COMMA- denotes ,
T9113 18220-18227 JJ denotes massive
T9114 18228-18237 NN denotes apoptosis
T9115 18237-18238 -COMMA- denotes ,
T9116 18239-18242 CC denotes and
T9117 18243-18253 JJ denotes subsequent
T9118 18254-18265 NN denotes development
T9119 18266-18268 IN denotes of
T9120 18269-18270 NN denotes B
T9121 18271-18275 NN denotes cell
T9122 18276-18285 NN denotes lymphomas
T9123 18286-18287 -LRB- denotes [
T9124 18287-18289 CD denotes 35
T9125 18289-18290 -RRB- denotes ]
T9126 18292-18300 RB denotes Moreover
T9127 18300-18301 -COMMA- denotes ,
T9128 18302-18307 NN denotes BMP-6
T9129 18308-18311 VB denotes has
T9130 18312-18316 VB denotes been
T9131 18317-18326 VB denotes suggested
T9132 18327-18329 TO denotes to
T9133 18330-18334 VB denotes play
T9134 18335-18336 DT denotes a
T9135 18337-18341 NN denotes role
T9136 18342-18344 IN denotes in
T9137 18345-18355 JJ denotes rheumatoid
T9138 18356-18365 NN denotes arthritis
T9139 18366-18367 -LRB- denotes (
T9140 18367-18369 NN denotes RA
T9141 18369-18370 -RRB- denotes )
T9142 18371-18372 -LRB- denotes [
T9143 18372-18377 CD denotes 43,44
T9144 18377-18378 -RRB- denotes ]
T9145 18379-18382 CC denotes and
T9146 18383-18391 JJ denotes elevated
T9147 18392-18398 NN denotes levels
T9148 18399-18401 IN denotes of
T9149 18402-18405 NN denotes Id1
T9150 18406-18409 CC denotes and
T9151 18410-18413 NN denotes Id3
T9152 18414-18418 VB denotes have
T9153 18419-18423 VB denotes been
T9154 18424-18429 VB denotes found
T9155 18430-18432 IN denotes in
T9156 18433-18436 DT denotes the
T9157 18437-18444 NN denotes synovia
T9158 18445-18447 IN denotes of
T9159 18448-18459 NN denotes RA-patients
T9160 18460-18461 -LRB- denotes [
T9161 18461-18463 CD denotes 45
T9162 18463-18464 -RRB- denotes ]
T9163 18466-18476 RB denotes Altogether
T9164 18476-18477 -COMMA- denotes ,
T9165 18478-18483 DT denotes these
T9166 18484-18491 NN denotes results
T9167 18492-18497 VB denotes point
T9168 18498-18500 TO denotes to
T9169 18501-18503 DT denotes an
T9170 18504-18513 JJ denotes important
T9171 18514-18518 NN denotes role
T9172 18519-18522 IN denotes for
T9173 18523-18525 NN denotes Id
T9174 18526-18534 NN denotes proteins
T9175 18535-18537 IN denotes in
T9176 18538-18541 DT denotes the
T9177 18542-18552 NN denotes regulation
T9178 18553-18555 IN denotes of
T9179 18556-18562 JJ denotes normal
T9180 18563-18564 NN denotes B
T9181 18565-18569 NN denotes cell
T9182 18570-18581 NN denotes homeostasis
T9183 18582-18585 CC denotes and
T9184 18586-18588 IN denotes in
T9185 18589-18597 NN denotes diseases
T9186 18597-18598 -COMMA- denotes ,
T9187 18599-18604 WRB denotes where
T9188 18605-18606 NN denotes B
T9189 18607-18612 NN denotes cells
T9190 18613-18616 VB denotes are
T9191 18617-18625 VB denotes involved
T9192 18627-18629 PRP denotes It
T9193 18630-18634 MD denotes will
T9194 18635-18644 RB denotes therefore
T9195 18645-18647 VB denotes be
T9196 18648-18657 JJ denotes important
T9197 18658-18660 TO denotes to
T9198 18661-18668 RB denotes further
T9199 18669-18678 VB denotes elucidate
T9200 18679-18682 DT denotes the
T9201 18683-18687 NN denotes role
T9202 18688-18690 IN denotes of
T9203 18691-18695 NN denotes Id-1
T9204 18696-18698 IN denotes in
T9205 18699-18704 JJ denotes human
T9206 18705-18706 NN denotes B
T9207 18707-18712 NN denotes cells
T9208 18713-18715 IN denotes by
T9209 18716-18725 JJ denotes selective
T9210 18726-18730 IN denotes over
T9211 18731-18741 NN denotes expression
T9212 18742-18744 CC denotes or
T9213 18745-18755 NN denotes inhibition
T9214 18756-18758 IN denotes of
T9215 18759-18763 NN denotes Id-1
T9216 18764-18768 NN denotes gene
T9217 18769-18779 NN denotes expression
T9218 18781-18786 VB denotes Given
T9219 18787-18790 DT denotes the
T9220 18791-18795 NN denotes role
T9221 18796-18798 IN denotes of
T9222 18799-18804 NN denotes BMP-6
T9223 18805-18807 IN denotes in
T9224 18808-18814 JJ denotes mature
T9225 18815-18820 JJ denotes human
T9226 18821-18822 NN denotes B
T9227 18823-18828 NN denotes cells
T9228 18829-18841 VB denotes demonstrated
T9229 18842-18846 RB denotes here
T9230 18846-18847 -COMMA- denotes ,
T9231 18848-18862 NN denotes identification
T9232 18863-18865 IN denotes of
T9233 18866-18871 NN denotes BMP-6
T9234 18872-18881 VB denotes producing
T9235 18882-18887 NN denotes cells
T9236 18888-18890 FW denotes in
T9237 18891-18895 FW denotes vivo
T9238 18896-18900 IN denotes with
T9239 18901-18912 NN denotes possibility
T9240 18913-18915 IN denotes of
T9241 18916-18927 NN denotes interaction
T9242 18928-18932 IN denotes with
T9243 18933-18938 NN denotes naïve
T9244 18939-18942 CC denotes and
T9245 18943-18949 NN denotes memory
T9246 18950-18951 NN denotes B
T9247 18952-18957 NN denotes cells
T9248 18958-18963 MD denotes might
T9249 18964-18974 VB denotes contribute
T9250 18975-18977 TO denotes to
T9251 18978-18981 DT denotes the
T9252 18982-18995 NN denotes understanding
T9253 18996-18998 IN denotes of
T9254 18999-19005 JJ denotes mature
T9255 19006-19007 NN denotes B
T9256 19008-19012 NN denotes cell
T9257 19013-19020 NN denotes biology
T9258 19022-19026 JJ denotes High
T9259 19027-19032 NN denotes BMP-6
T9260 19033-19037 NN denotes mRNA
T9261 19038-19048 NN denotes expression
T9262 19049-19051 IN denotes in
T9263 19052-19057 NN denotes DLBCL
T9264 19058-19061 VB denotes has
T9265 19062-19066 VB denotes been
T9266 19067-19075 VB denotes detected
T9267 19076-19078 IN denotes by
T9268 19079-19083 NN denotes gene
T9269 19084-19094 NN denotes expression
T9270 19095-19104 NN denotes profiling
T9271 19105-19106 -LRB- denotes [
T9272 19106-19108 CD denotes 12
T9273 19108-19109 -RRB- denotes ]
T9274 19111-19122 RB denotes Furthermore
T9275 19122-19123 -COMMA- denotes ,
T9276 19124-19134 NN denotes production
T9277 19135-19137 IN denotes of
T9278 19138-19143 NN denotes BMP-6
T9279 19144-19155 NN denotes transcripts
T9280 19156-19158 IN denotes in
T9281 19159-19165 JJ denotes normal
T9282 19166-19175 VB denotes activated
T9283 19176-19177 NN denotes B
T9284 19178-19183 NN denotes cells
T9285 19184-19187 VB denotes was
T9286 19188-19196 VB denotes detected
T9287 19197-19199 IN denotes in
T9288 19200-19203 DT denotes the
T9289 19204-19208 JJ denotes same
T9290 19209-19214 NN denotes study
T9291 19216-19218 IN denotes Of
T9292 19219-19223 NN denotes note
T9293 19223-19224 -COMMA- denotes ,
T9294 19225-19227 DT denotes an
T9295 19228-19237 JJ denotes autocrine
T9296 19238-19243 NN denotes BMP-6
T9297 19244-19248 NN denotes loop
T9298 19249-19252 VB denotes has
T9299 19253-19257 VB denotes been
T9300 19258-19266 VB denotes reported
T9301 19267-19269 IN denotes by
T9302 19270-19276 NN denotes others
T9303 19277-19279 IN denotes in
T9304 19280-19292 NN denotes chondrocytes
T9305 19293-19296 CC denotes and
T9306 19297-19299 IN denotes in
T9307 19300-19303 DT denotes the
T9308 19304-19311 NN denotes ovarium
T9309 19312-19313 -LRB- denotes [
T9310 19313-19321 CD denotes 46,19,18
T9311 19321-19322 -RRB- denotes ]
T9312 19324-19333 RB denotes Therefore
T9313 19333-19334 -COMMA- denotes ,
T9314 19335-19337 PRP denotes we
T9315 19338-19344 VB denotes wanted
T9316 19345-19347 TO denotes to
T9317 19348-19355 VB denotes explore
T9318 19356-19359 DT denotes the
T9319 19360-19371 NN denotes possibility
T9320 19372-19375 IN denotes for
T9321 19376-19378 DT denotes an
T9322 19379-19388 JJ denotes autocrine
T9323 19389-19394 NN denotes BMP-6
T9324 19395-19399 NN denotes loop
T9325 19400-19402 IN denotes in
T9326 19403-19408 JJ denotes human
T9327 19409-19410 NN denotes B
T9328 19411-19416 NN denotes cells
T9329 19418-19420 PRP denotes We
T9330 19421-19429 VB denotes analysed
T9331 19430-19433 DT denotes the
T9332 19434-19444 NN denotes expression
T9333 19445-19450 NN denotes BMP-6
T9334 19451-19455 NN denotes mRNA
T9335 19456-19458 IN denotes in
T9336 19459-19469 JJ denotes peripheral
T9337 19470-19475 NN denotes blood
T9338 19476-19477 NN denotes B
T9339 19478-19483 NN denotes cells
T9340 19484-19486 IN denotes by
T9341 19487-19496 JJ denotes real-time
T9342 19497-19500 NN denotes PCR
T9343 19500-19501 -COMMA- denotes ,
T9344 19502-19505 CC denotes and
T9345 19506-19512 NN denotes report
T9346 19513-19517 RB denotes here
T9347 19518-19521 DT denotes the
T9348 19522-19534 NN denotes upregulation
T9349 19535-19537 IN denotes of
T9350 19538-19548 JJ denotes endogenous
T9351 19549-19554 NN denotes BMP-6
T9352 19555-19566 NN denotes transcripts
T9353 19567-19572 IN denotes after
T9354 19573-19584 NN denotes stimulation
T9355 19585-19589 IN denotes with
T9356 19590-19593 NN denotes FCS
T9357 19593-19594 -COMMA- denotes ,
T9358 19595-19600 JJ denotes human
T9359 19601-19609 NN denotes AB-serum
T9360 19610-19613 CC denotes and
T9361 19613-19614 -COMMA- denotes ,
T9362 19615-19619 RB denotes most
T9363 19620-19631 RB denotes importantly
T9364 19631-19632 -COMMA- denotes ,
T9365 19633-19641 JJ denotes anti-IgM
T9366 19643-19650 RB denotes However
T9367 19650-19651 -COMMA- denotes ,
T9368 19652-19655 PRP-DOLLAR- denotes our
T9369 19656-19664 NN denotes attempts
T9370 19665-19667 TO denotes to
T9371 19668-19673 VB denotes study
T9372 19674-19679 NN denotes BMP-6
T9373 19680-19687 NN denotes protein
T9374 19688-19694 NN denotes levels
T9375 19695-19699 VB denotes were
T9376 19700-19712 JJ denotes unsuccessful
T9377 19713-19716 JJ denotes due
T9378 19717-19719 TO denotes to
T9379 19720-19728 NN denotes problems
T9380 19729-19733 IN denotes with
T9381 19734-19744 JJ denotes unspecific
T9382 19745-19752 NN denotes binding
T9383 19753-19755 IN denotes of
T9384 19756-19759 DT denotes the
T9385 19760-19770 JJ denotes anti-BMP-6
T9386 19771-19781 NN denotes antibodies
T9387 19782-19788 VB denotes tested
T9388 19788-19789 -COMMA- denotes ,
T9389 19790-19793 CC denotes and
T9390 19794-19798 NN denotes lack
T9391 19799-19801 IN denotes of
T9392 19802-19810 JJ denotes specific
T9393 19811-19819 NN denotes staining
T9394 19820-19822 IN denotes in
T9395 19823-19830 NN denotes control
T9396 19831-19836 NN denotes cells
T9397 19837-19842 VB denotes known
T9398 19843-19845 TO denotes to
T9399 19846-19853 VB denotes express
T9400 19854-19859 NN denotes BMP-6
T9401 19860-19864 NN denotes mRNA
T9402 19866-19868 IN denotes In
T9403 19869-19877 NN denotes contrast
T9404 19877-19878 -COMMA- denotes ,
T9405 19879-19882 DT denotes the
T9406 19883-19894 JJ denotes recombinant
T9407 19895-19902 NN denotes protein
T9408 19903-19906 VB denotes was
T9409 19907-19914 RB denotes readily
T9410 19915-19923 VB denotes detected
T9411 19925-19927 IN denotes In
T9412 19928-19932 DT denotes that
T9413 19933-19940 NN denotes respect
T9414 19940-19941 -COMMA- denotes ,
T9415 19942-19945 JJ denotes few
T9416 19946-19959 NN denotes investigators
T9417 19960-19964 VB denotes have
T9418 19965-19973 VB denotes detected
T9419 19974-19979 NN denotes BMP-6
T9420 19980-19987 NN denotes protein
T9421 19988-19990 IN denotes in
T9422 19991-19997 NN denotes humans
T9423 19997-19998 -COMMA- denotes ,
T9424 19999-20009 RB denotes especially
T9425 20010-20012 IN denotes in
T9426 20013-20027 JJ denotes non-pathogenic
T9427 20028-20034 NN denotes tissue
T9428 20036-20039 DT denotes The
T9429 20040-20051 NN denotes possibility
T9430 20052-20054 IN denotes of
T9431 20055-20060 NN denotes BMP-6
T9432 20061-20071 NN denotes production
T9433 20072-20074 IN denotes in
T9434 20075-20080 JJ denotes human
T9435 20081-20088 NN denotes B-cells
T9436 20089-20091 VB denotes is
T9437 20092-20094 IN denotes in
T9438 20095-20099 NN denotes line
T9439 20100-20104 IN denotes with
T9440 20105-20106 DT denotes a
T9441 20107-20113 JJ denotes recent
T9442 20114-20118 NN denotes work
T9443 20119-20123 WDT denotes that
T9444 20124-20132 VB denotes reported
T9445 20133-20136 DT denotes the
T9446 20137-20147 NN denotes production
T9447 20148-20150 IN denotes of
T9448 20151-20156 NN denotes BMP-6
T9449 20157-20159 IN denotes in
T9450 20160-20165 NN denotes mouse
T9451 20166-20167 NN denotes B
T9452 20168-20173 NN denotes cells
T9453 20173-20174 -COMMA- denotes ,
T9454 20175-20187 VB denotes infiltrating
T9455 20188-20191 DT denotes the
T9456 20192-20196 NN denotes bone
T9457 20197-20203 NN denotes marrow
T9458 20204-20206 IN denotes of
T9459 20207-20211 NN denotes mice
T9460 20212-20216 IN denotes with
T9461 20217-20229 JJ denotes inflammatory
T9462 20230-20239 NN denotes arthritis
T9463 20240-20241 -LRB- denotes [
T9464 20241-20243 CD denotes 43
T9465 20243-20244 -RRB- denotes ]
T9466 20246-20248 IN denotes In
T9467 20249-20253 DT denotes this
T9468 20254-20259 NN denotes study
T9469 20259-20260 -COMMA- denotes ,
T9470 20261-20262 DT denotes a
T9471 20263-20267 NN denotes role
T9472 20268-20271 IN denotes for
T9473 20272-20276 NN denotes BMPs
T9474 20277-20279 IN denotes in
T9475 20280-20283 DT denotes the
T9476 20284-20297 JJ denotes inflammatoric
T9477 20298-20305 NN denotes process
T9478 20306-20308 IN denotes of
T9479 20309-20318 NN denotes arthritis
T9480 20319-20322 VB denotes was
T9481 20323-20332 VB denotes suggested
T9482 20334-20337 DT denotes The
T9483 20338-20350 NN denotes upregulation
T9484 20351-20353 IN denotes of
T9485 20354-20357 DT denotes the
T9486 20358-20375 NN denotes BMP-6-transcripts
T9487 20376-20381 IN denotes after
T9488 20382-20398 NN denotes IgM-crosslinking
T9489 20399-20401 VB denotes is
T9490 20402-20404 IN denotes of
T9491 20405-20421 JJ denotes pathophysiologic
T9492 20422-20430 NN denotes interest
T9493 20431-20432 -LRB- denotes [
T9494 20432-20434 CD denotes 12
T9495 20434-20435 -RRB- denotes ]
T9496 20437-20438 DT denotes A
T9497 20439-20443 NN denotes loss
T9498 20444-20446 IN denotes of
T9499 20447-20467 NN denotes TGF-β-responsiveness
T9500 20468-20471 VB denotes has
T9501 20472-20476 VB denotes been
T9502 20477-20486 VB denotes suggested
T9503 20487-20489 TO denotes to
T9504 20490-20492 VB denotes be
T9505 20493-20494 DT denotes a
T9506 20495-20503 JJ denotes critical
T9507 20504-20516 NN denotes contribution
T9508 20517-20519 TO denotes to
T9509 20520-20529 JJ denotes malignant
T9510 20530-20544 NN denotes transformation
T9511 20545-20546 -LRB- denotes [
T9512 20546-20551 CD denotes 47,48
T9513 20551-20552 -RRB- denotes ]
T9514 20553-20556 CC denotes and
T9515 20557-20564 JJ denotes similar
T9516 20565-20574 JJ denotes oncogenic
T9517 20575-20585 NN denotes mechanisms
T9518 20586-20590 VB denotes have
T9519 20591-20595 VB denotes been
T9520 20596-20606 VB denotes postulated
T9521 20607-20610 IN denotes for
T9522 20611-20615 NN denotes BMPs
T9523 20617-20622 NN denotes Lines
T9524 20623-20625 IN denotes of
T9525 20626-20634 NN denotes evidence
T9526 20635-20642 VB denotes suggest
T9527 20643-20644 -LRB- denotes [
T9528 20644-20646 CD denotes 49
T9529 20646-20647 -RRB- denotes ]
T9530 20648-20652 IN denotes that
T9531 20653-20655 IN denotes at
T9532 20656-20661 JJ denotes early
T9533 20662-20668 NN denotes stages
T9534 20669-20671 IN denotes of
T9535 20672-20686 NN denotes carcinogenesis
T9536 20686-20687 -COMMA- denotes ,
T9537 20688-20693 NN denotes BMP-6
T9538 20694-20696 VB denotes is
T9539 20697-20700 RB denotes not
T9540 20701-20702 DT denotes a
T9541 20703-20709 NN denotes tumour
T9542 20710-20718 NN denotes promoter
T9543 20718-20719 -COMMA- denotes ,
T9544 20720-20723 CC denotes but
T9545 20724-20734 VB denotes suppresses
T9546 20735-20741 JJ denotes benign
T9547 20742-20745 CC denotes and
T9548 20746-20755 JJ denotes malignant
T9549 20756-20762 NN denotes tumour
T9550 20763-20772 NN denotes outgrowth
T9551 20774-20779 DT denotes These
T9552 20780-20788 NN denotes findings
T9553 20789-20792 VB denotes are
T9554 20793-20795 IN denotes in
T9555 20796-20800 JJ denotes good
T9556 20801-20810 NN denotes agreement
T9557 20811-20815 IN denotes with
T9558 20816-20824 JJ denotes previous
T9559 20825-20833 NN denotes findings
T9560 20834-20837 IN denotes for
T9561 20838-20843 JJ denotes other
T9562 20844-20849 NN denotes TGF-β
T9563 20850-20856 NN denotes family
T9564 20857-20864 NN denotes members
T9565 20864-20865 -COMMA- denotes ,
T9566 20866-20875 VB denotes including
T9567 20876-20882 NN denotes TGF-β1
T9568 20883-20886 CC denotes and
T9569 20887-20892 NN denotes BMP-4
T9570 20893-20894 -LRB- denotes [
T9571 20894-20896 CD denotes 50
T9572 20896-20897 -RRB- denotes ]
T9573 20897-20898 -COMMA- denotes ,
T9574 20899-20909 VB denotes indicating
T9575 20910-20914 IN denotes that
T9576 20915-20923 JJ denotes cellular
T9577 20924-20931 NN denotes context
T9578 20932-20934 IN denotes of
T9579 20935-20938 DT denotes the
T9580 20939-20942 NN denotes BMP
T9581 20943-20949 NN denotes target
T9582 20950-20954 NN denotes cell
T9583 20955-20960 MD denotes might
T9584 20961-20967 VB denotes define
T9585 20968-20971 DT denotes the
T9586 20972-20979 JJ denotes various
T9587 20980-20988 VB denotes observed
T9588 20989-20996 NN denotes effects
T9589 20998-21000 IN denotes In
T9590 21001-21009 NN denotes contrast
T9591 21010-21012 TO denotes to
T9592 21013-21016 DT denotes the
T9593 21017-21029 NN denotes upregulation
T9594 21030-21032 IN denotes of
T9595 21033-21038 NN denotes BMP-6
T9596 21039-21049 NN denotes transcript
T9597 21050-21052 IN denotes in
T9598 21053-21054 NN denotes B
T9599 21055-21060 NN denotes cells
T9600 21060-21061 -COMMA- denotes ,
T9601 21062-21064 PRP denotes we
T9602 21065-21069 VB denotes were
T9603 21070-21073 RB denotes not
T9604 21074-21078 JJ denotes able
T9605 21079-21081 TO denotes to
T9606 21082-21088 VB denotes detect
T9607 21089-21094 NN denotes BMP-6
T9608 21095-21106 NN denotes transcripts
T9609 21107-21109 IN denotes in
T9610 21110-21115 JJ denotes human
T9611 21116-21126 JJ denotes peripheral
T9612 21127-21132 NN denotes blood
T9613 21133-21137 JJ denotes CD4+
T9614 21138-21140 CC denotes or
T9615 21141-21145 JJ denotes CD8+
T9616 21146-21147 NN denotes T
T9617 21148-21153 NN denotes cells
T9618 21154-21155 -LRB- denotes (
T9619 21155-21162 VB denotes resting
T9620 21163-21165 CC denotes or
T9621 21166-21176 VB denotes stimulated
T9622 21177-21181 IN denotes with
T9623 21182-21190 JJ denotes anti-CD3
T9624 21191-21194 CC denotes and
T9625 21195-21204 JJ denotes anti-CD28
T9626 21204-21205 -COLON- denotes ;
T9627 21206-21210 NN denotes data
T9628 21211-21214 RB denotes not
T9629 21215-21220 VB denotes shown
T9630 21220-21221 -RRB- denotes )
T9631 21221-21222 -COMMA- denotes ,
T9632 21223-21233 JJ denotes consistent
T9633 21234-21238 IN denotes with
T9634 21239-21242 DT denotes the
T9635 21243-21251 NN denotes findings
T9636 21252-21254 IN denotes in
T9637 21255-21256 NN denotes T
T9638 21257-21261 NN denotes cell
T9639 21262-21267 NN denotes lines
T9640 21268-21269 -LRB- denotes [
T9641 21269-21271 CD denotes 20
T9642 21271-21272 -RRB- denotes ]
T9643 21273-21276 CC denotes and
T9644 21277-21278 NN denotes T
T9645 21279-21284 NN denotes cells
T9646 21285-21287 IN denotes in
T9647 21288-21292 NN denotes mice
T9648 21293-21294 -LRB- denotes [
T9649 21294-21296 CD denotes 43
T9650 21296-21297 -RRB- denotes ]
T9651 21299-21304 JJ denotes Other
T9652 21305-21314 JJ denotes potential
T9653 21315-21320 NN denotes BMP-6
T9654 21321-21328 NN denotes sources
T9655 21329-21332 IN denotes for
T9656 21333-21339 JJ denotes mature
T9657 21340-21341 NN denotes B
T9658 21342-21347 NN denotes cells
T9659 21348-21350 FW denotes in
T9660 21351-21355 FW denotes vivo
T9661 21356-21361 MD denotes might
T9662 21362-21364 VB denotes be
T9663 21365-21370 JJ denotes other
T9664 21371-21376 NN denotes cells
T9665 21377-21379 IN denotes of
T9666 21380-21383 DT denotes the
T9667 21384-21390 JJ denotes immune
T9668 21391-21397 NN denotes system
T9669 21398-21400 CC denotes or
T9670 21401-21407 NN denotes tissue
T9671 21408-21412 IN denotes with
T9672 21413-21420 NN denotes contact
T9673 21421-21423 TO denotes to
T9674 21424-21427 DT denotes the
T9675 21428-21441 JJ denotes hematopoietic
T9676 21442-21448 NN denotes system
T9677 21450-21453 CD denotes One
T9678 21454-21458 RB denotes well
T9679 21459-21469 VB denotes recognized
T9680 21470-21476 NN denotes source
T9681 21477-21480 IN denotes for
T9682 21481-21486 NN denotes BMP-6
T9683 21487-21497 NN denotes production
T9684 21498-21500 VB denotes is
T9685 21501-21504 DT denotes the
T9686 21505-21510 JJ denotes human
T9687 21511-21515 NN denotes bone
T9688 21516-21519 CC denotes and
T9689 21520-21524 NN denotes bone
T9690 21525-21531 NN denotes marrow
T9691 21532-21538 NN denotes stroma
T9692 21539-21540 -LRB- denotes [
T9693 21540-21544 CD denotes 51,8
T9694 21544-21545 -RRB- denotes ]
T9695 21547-21558 RB denotes Furthermore
T9696 21558-21559 -COMMA- denotes ,
T9697 21560-21562 PRP denotes it
T9698 21563-21565 VB denotes is
T9699 21566-21576 JJ denotes noteworthy
T9700 21577-21581 IN denotes that
T9701 21582-21587 JJ denotes human
T9702 21588-21597 JJ denotes umbilical
T9703 21598-21602 NN denotes vein
T9704 21603-21614 JJ denotes endothelial
T9705 21615-21620 NN denotes cells
T9706 21621-21622 -LRB- denotes (
T9707 21622-21627 NN denotes HUVEC
T9708 21627-21628 -RRB- denotes )
T9709 21629-21635 RB denotes highly
T9710 21636-21643 VB denotes express
T9711 21644-21649 NN denotes BMP-6
T9712 21650-21654 NN denotes mRNA
T9713 21655-21656 -LRB- denotes [
T9714 21656-21658 CD denotes 52
T9715 21658-21659 -RRB- denotes ]
T9716 21659-21660 -COMMA- denotes ,
T9717 21661-21664 CC denotes and
T9718 21665-21673 JJ denotes vascular
T9719 21674-21685 NN denotes endothelium
T9720 21686-21689 VB denotes has
T9721 21690-21694 VB denotes been
T9722 21695-21703 VB denotes reported
T9723 21704-21706 TO denotes to
T9724 21707-21714 VB denotes produce
T9725 21715-21720 NN denotes BMP-6
T9726 21721-21722 -LRB- denotes [
T9727 21722-21724 CD denotes 53
T9728 21724-21725 -RRB- denotes ]
T9729 21727-21732 DT denotes These
T9730 21733-21740 NN denotes studies
T9731 21741-21746 MD denotes might
T9732 21747-21752 VB denotes imply
T9733 21753-21754 DT denotes a
T9734 21755-21759 NN denotes role
T9735 21760-21763 IN denotes for
T9736 21764-21769 NN denotes BMP-6
T9737 21770-21772 IN denotes in
T9738 21773-21789 JJ denotes transendothelial
T9739 21790-21799 NN denotes migration
T9740 21800-21802 IN denotes of
T9741 21803-21804 NN denotes B
T9742 21805-21810 NN denotes cells
T9743 21812-21817 NN denotes BMP-6
T9744 21818-21822 NN denotes mRNA
T9745 21823-21826 VB denotes has
T9746 21827-21831 VB denotes been
T9747 21832-21844 VB denotes demonstrated
T9748 21845-21847 IN denotes in
T9749 21848-21854 JJ denotes murine
T9750 21855-21865 NN denotes macrophage
T9751 21866-21870 NN denotes cell
T9752 21871-21876 NN denotes lines
T9753 21876-21877 -COMMA- denotes ,
T9754 21878-21881 CC denotes but
T9755 21882-21885 RB denotes not
T9756 21886-21888 IN denotes in
T9757 21889-21895 NN denotes humans
T9758 21896-21897 -LRB- denotes [
T9759 21897-21899 CD denotes 54
T9760 21899-21900 -RRB- denotes ]
T9761 21902-21904 IN denotes In
T9762 21905-21915 NN denotes accordance
T9763 21916-21920 IN denotes with
T9764 21921-21926 DT denotes these
T9765 21927-21935 NN denotes findings
T9766 21935-21936 -COMMA- denotes ,
T9767 21937-21942 JJ denotes other
T9768 21943-21948 JJ denotes human
T9769 21949-21953 NN denotes cell
T9770 21954-21959 NN denotes lines
T9771 21960-21962 IN denotes of
T9772 21963-21973 NN denotes neutrophil
T9773 21974-21977 CC denotes and
T9774 21978-21987 JJ denotes monocytic
T9775 21988-21994 NN denotes origin
T9776 21995-21999 VB denotes have
T9777 22000-22004 VB denotes been
T9778 22005-22014 VB denotes described
T9779 22015-22017 TO denotes to
T9780 22018-22020 VB denotes be
T9781 22021-22029 JJ denotes negative
T9782 22030-22033 IN denotes for
T9783 22034-22037 DT denotes the
T9784 22038-22043 NN denotes BMP-6
T9785 22044-22054 NN denotes transcript
T9786 22055-22056 -LRB- denotes [
T9787 22056-22058 CD denotes 20
T9788 22058-22059 -RRB- denotes ]
T9789 22061-22063 TO denotes To
T9790 22064-22067 PRP-DOLLAR- denotes our
T9791 22068-22077 NN denotes knowledge
T9792 22077-22078 -COMMA- denotes ,
T9793 22079-22084 EX denotes there
T9794 22085-22087 VB denotes is
T9795 22088-22097 RB denotes currently
T9796 22098-22100 DT denotes no
T9797 22101-22107 NN denotes report
T9798 22108-22113 IN denotes about
T9799 22114-22119 NN denotes BMP-6
T9800 22120-22130 NN denotes production
T9801 22131-22133 IN denotes of
T9802 22134-22139 JJ denotes human
T9803 22140-22149 JJ denotes dendritic
T9804 22150-22155 NN denotes cells
T13413 22169-22171 IN denotes In
T13414 22172-22182 NN denotes conclusion
T13415 22182-22183 -COMMA- denotes ,
T13416 22184-22187 PRP-DOLLAR- denotes our
T13417 22188-22195 NN denotes results
T13418 22196-22200 VB denotes show
T13419 22201-22205 IN denotes that
T13420 22206-22211 NN denotes BMP-6
T13421 22212-22219 VB denotes induces
T13422 22220-22230 NN denotes activation
T13423 22231-22233 IN denotes of
T13424 22234-22247 JJ denotes intracellular
T13425 22248-22252 NN denotes Smad
T13426 22253-22263 NN denotes signalling
T13427 22264-22266 IN denotes in
T13428 22267-22273 JJ denotes mature
T13429 22274-22279 JJ denotes human
T13430 22280-22287 NN denotes B-cells
T13431 22288-22292 IN denotes with
T13432 22293-22304 JJ denotes consecutive
T13433 22305-22315 NN denotes production
T13434 22316-22318 IN denotes of
T13435 22319-22322 NN denotes Id1
T13436 22323-22330 NN denotes protein
T13437 22332-22343 RB denotes Furthermore
T13438 22343-22344 -COMMA- denotes ,
T13439 22345-22347 PRP denotes we
T13440 22348-22354 VB denotes report
T13441 22355-22359 IN denotes that
T13442 22360-22365 NN denotes BMP-6
T13443 22366-22369 VB denotes has
T13444 22370-22372 DT denotes an
T13445 22373-22390 JJ denotes antiproliferative
T13446 22391-22397 NN denotes effect
T13447 22398-22400 IN denotes in
T13448 22401-22402 NN denotes B
T13449 22403-22408 NN denotes cells
T13450 22409-22419 VB denotes stimulated
T13451 22420-22424 IN denotes with
T13452 22425-22433 NN denotes anti-IgM
T13453 22434-22439 RB denotes alone
T13454 22440-22442 CC denotes or
T13455 22443-22446 DT denotes the
T13456 22447-22455 VB denotes combined
T13457 22456-22462 NN denotes action
T13458 22463-22465 IN denotes of
T13459 22466-22474 JJ denotes anti-IgM
T13460 22475-22478 CC denotes and
T13461 22479-22484 NN denotes CD40L
T13462 22486-22498 RB denotes Additionally
T13463 22498-22499 -COMMA- denotes ,
T13464 22500-22505 NN denotes BMP-6
T13465 22506-22513 VB denotes induces
T13466 22514-22518 NN denotes cell
T13467 22519-22524 NN denotes death
T13468 22525-22527 IN denotes in
T13469 22528-22537 VB denotes activated
T13470 22538-22544 NN denotes memory
T13471 22545-22546 NN denotes B
T13472 22547-22552 NN denotes cells
T13473 22553-22556 CC denotes and
T13474 22557-22562 NN denotes Ramos
T13475 22563-22568 NN denotes cells
T13476 22570-22575 VB denotes Taken
T13477 22576-22584 RB denotes together
T13478 22584-22585 -COMMA- denotes ,
T13479 22586-22591 DT denotes these
T13480 22592-22599 NN denotes results
T13481 22600-22607 VB denotes provide
T13482 22608-22609 DT denotes a
T13483 22610-22619 NN denotes rationale
T13484 22620-22622 TO denotes to
T13485 22623-22630 RB denotes further
T13486 22631-22638 VB denotes examine
T13487 22639-22642 DT denotes the
T13488 22643-22647 NN denotes role
T13489 22648-22650 IN denotes of
T13490 22651-22656 NN denotes BMP-6
T13491 22657-22667 NN denotes signalling
T13492 22668-22670 IN denotes in
T13493 22671-22677 JJ denotes normal
T13494 22678-22679 NN denotes B
T13495 22680-22684 NN denotes cell
T13496 22685-22692 NN denotes biology
T13497 22693-22695 RB denotes as
T13498 22696-22700 RB denotes well
T13499 22701-22703 IN denotes as
T13500 22704-22706 IN denotes in
T13501 22707-22717 JJ denotes pathologic
T13502 22718-22728 NN denotes conditions
T13503 22729-22733 IN denotes like
T13504 22734-22735 NN denotes B
T13505 22736-22740 NN denotes cell
T13506 22741-22753 NN denotes malignancies
T13507 22754-22757 CC denotes and
T13508 22758-22768 JJ denotes autoimmune
T13509 22769-22778 NN denotes disorders
T13708 22790-22794 NN denotes Cell
T13709 22795-22802 NN denotes culture
T13710 22803-22805 IN denotes If
T13711 22806-22809 RB denotes not
T13712 22810-22819 VB denotes specified
T13713 22819-22820 -COMMA- denotes ,
T13714 22821-22824 DT denotes all
T13715 22825-22830 NN denotes cells
T13716 22831-22835 VB denotes were
T13717 22836-22844 VB denotes cultured
T13718 22845-22847 IN denotes in
T13719 22848-22854 NN denotes X-VIVO
T13720 22855-22858 CD denotes 15™
T13721 22859-22860 -LRB- denotes (
T13722 22860-22872 NNP denotes BioWhittaker
T13723 22872-22873 -COMMA- denotes ,
T13724 22874-22882 NNP denotes Verviers
T13725 22882-22883 -COMMA- denotes ,
T13726 22884-22891 NNP denotes Belgium
T13727 22891-22892 -RRB- denotes )
T13728 22893-22903 JJ denotes serum-free
T13729 22904-22910 NN denotes medium
T13730 22911-22913 IN denotes at
T13731 22914-22918 NN denotes 37°C
T13732 22919-22922 CC denotes and
T13733 22923-22924 CD denotes 5
T13734 22924-22925 NN denotes %
T13735 22926-22929 NN denotes CO2
T13736 22930-22932 IN denotes in
T13737 22933-22936 NN denotes air
T13738 22938-22948 JJ denotes Peripheral
T13739 22949-22954 NN denotes blood
T13740 22955-22958 VB denotes was
T13741 22959-22967 VB denotes provided
T13742 22968-22970 IN denotes by
T13743 22971-22974 DT denotes the
T13744 22975-22980 NNP denotes Blood
T13745 22981-22985 NNP denotes Bank
T13746 22986-22988 IN denotes at
T13747 22989-22997 NNP denotes Buskerud
T13748 22998-23006 NNP denotes Regional
T13749 23007-23015 NNP denotes Hospital
T13750 23016-23020 IN denotes with
T13751 23021-23027 JJ denotes formal
T13752 23028-23037 NN denotes agreement
T13753 23038-23040 IN denotes by
T13754 23041-23044 DT denotes the
T13755 23045-23053 NN denotes patients
T13756 23053-23054 -COMMA- denotes ,
T13757 23055-23058 CC denotes and
T13758 23059-23067 NN denotes approval
T13759 23068-23070 IN denotes by
T13760 23071-23074 DT denotes the
T13761 23075-23083 JJ denotes regional
T13762 23084-23090 NN denotes ethics
T13763 23091-23100 NN denotes committee
T13764 23102-23108 RB denotes Highly
T13765 23109-23117 VB denotes purified
T13766 23118-23125 VB denotes resting
T13767 23126-23131 JJ denotes human
T13768 23132-23145 NN denotes B-lymphocytes
T13769 23146-23147 -LRB- denotes (
T13770 23147-23152 JJ denotes CD19+
T13771 23153-23158 NN denotes cells
T13772 23158-23159 -RRB- denotes )
T13773 23160-23164 VB denotes were
T13774 23165-23173 VB denotes isolated
T13775 23174-23178 IN denotes from
T13776 23179-23182 DT denotes the
T13777 23183-23193 JJ denotes peripheral
T13778 23194-23199 NN denotes blood
T13779 23200-23202 IN denotes by
T13780 23203-23212 VB denotes rosetting
T13781 23213-23217 IN denotes with
T13782 23218-23232 JJ denotes immunomagnetic
T13783 23233-23238 NN denotes beads
T13784 23239-23240 -LRB- denotes (
T13785 23240-23249 NN denotes Dynabeads
T13786 23250-23254 NN denotes M450
T13787 23254-23255 -COLON- denotes ;
T13788 23256-23261 NNP denotes Dynal
T13789 23261-23262 -COMMA- denotes ,
T13790 23263-23267 NNP denotes Oslo
T13791 23267-23268 -COMMA- denotes ,
T13792 23269-23275 NNP denotes Norway
T13793 23275-23276 -RRB- denotes )
T13794 23277-23279 IN denotes as
T13795 23280-23289 VB denotes described
T13796 23290-23291 -LRB- denotes [
T13797 23291-23293 CD denotes 55
T13798 23293-23294 -RRB- denotes ]
T13799 23296-23300 DT denotes This
T13800 23301-23310 NN denotes procedure
T13801 23311-23317 VB denotes yields
T13802 23318-23322 JJ denotes less
T13803 23323-23327 IN denotes than
T13804 23328-23331 CD denotes 0.5
T13805 23331-23332 NN denotes %
T13806 23333-23334 NN denotes T
T13807 23335-23340 NN denotes cells
T13808 23340-23341 -COMMA- denotes ,
T13809 23342-23345 CD denotes 0.1
T13810 23345-23346 NN denotes %
T13811 23347-23349 NN denotes NK
T13812 23350-23355 NN denotes cells
T13813 23355-23356 -COMMA- denotes ,
T13814 23357-23360 CC denotes and
T13815 23361-23364 CD denotes 0.5
T13816 23364-23365 NN denotes %
T13817 23366-23375 NN denotes monocytes
T13818 23376-23378 IN denotes as
T13819 23379-23385 VB denotes judged
T13820 23386-23388 IN denotes by
T13821 23389-23397 JJ denotes indirect
T13822 23398-23416 NN denotes immunofluorescence
T13823 23417-23425 NN denotes staining
T13824 23427-23430 DT denotes The
T13825 23431-23440 VB denotes following
T13826 23441-23445 NN denotes cell
T13827 23446-23451 NN denotes lines
T13828 23452-23456 IN denotes from
T13829 23457-23462 JJ denotes human
T13830 23463-23471 JJ denotes lymphoid
T13831 23472-23484 NN denotes malignancies
T13832 23485-23489 VB denotes were
T13833 23490-23500 VB denotes maintained
T13834 23501-23503 IN denotes in
T13835 23504-23508 NN denotes RPMI
T13836 23509-23513 CD denotes 1640
T13837 23514-23515 -LRB- denotes (
T13838 23515-23518 NN denotes PAA
T13839 23519-23531 NNP denotes Laboratories
T13840 23532-23536 NNP denotes GmbH
T13841 23536-23537 -COMMA- denotes ,
T13842 23538-23546 NNP denotes Pasching
T13843 23546-23547 -COMMA- denotes ,
T13844 23548-23555 NNP denotes Austria
T13845 23555-23556 -RRB- denotes )
T13846 23557-23569 VB denotes supplemented
T13847 23570-23574 IN denotes with
T13848 23575-23577 CD denotes 10
T13849 23577-23578 NN denotes %
T13850 23579-23585 JJ denotes foetal
T13851 23586-23592 JJ denotes bovine
T13852 23593-23598 NN denotes serum
T13853 23599-23600 -LRB- denotes (
T13854 23600-23603 NN denotes FCS
T13855 23603-23604 -RRB- denotes )
T13856 23604-23605 -COMMA- denotes ,
T13857 23606-23609 CD denotes 100
T13858 23610-23618 NN denotes units/ml
T13859 23619-23629 NN denotes penicillin
T13860 23630-23631 NN denotes G
T13861 23631-23632 -COMMA- denotes ,
T13862 23633-23636 CC denotes and
T13863 23637-23640 CD denotes 100
T13864 23641-23649 NN denotes units/ml
T13865 23650-23652 IN denotes of
T13866 23653-23665 NN denotes streptomycin
T13867 23666-23674 NN denotes sulphate
T13868 23674-23675 -COMMA- denotes ,
T13869 23676-23679 CC denotes but
T13870 23680-23693 JJ denotes serum-starved
T13871 23694-23697 IN denotes for
T13872 23698-23700 IN denotes at
T13873 23701-23706 JJ denotes least
T13874 23707-23711 CD denotes four
T13875 23712-23717 NN denotes hours
T13876 23718-23721 CC denotes and
T13877 23722-23730 VB denotes cultured
T13878 23731-23733 IN denotes in
T13879 23734-23740 NN denotes X-VIVO
T13880 23741-23744 CD denotes 15™
T13881 23745-23749 WRB denotes when
T13882 23750-23758 VB denotes included
T13883 23759-23761 IN denotes in
T13884 23762-23773 NN denotes experiments
T13885 23773-23774 -COLON- denotes :
T13886 23775-23787 JJ denotes EBV-negative
T13887 23788-23790 NN denotes BL
T13888 23791-23795 NN denotes cell
T13889 23796-23801 NN denotes lines
T13890 23802-23807 NN denotes Ramos
T13891 23808-23809 -LRB- denotes (
T13892 23809-23814 NN denotes ECACC
T13893 23815-23823 CD denotes 85030802
T13894 23823-23824 -RRB- denotes )
T13895 23824-23825 -COMMA- denotes ,
T13896 23826-23830 NN denotes HL60
T13897 23831-23832 -LRB- denotes (
T13898 23832-23840 NN denotes JCRB0085
T13899 23840-23841 -RRB- denotes )
T14428 24387-24397 NN denotes Antibodies
T14429 24398-24402 VB denotes used
T14430 24403-24406 IN denotes for
T14431 24407-24411 NN denotes flow
T14432 24412-24422 JJ denotes cytometric
T14433 24423-24431 NN denotes analysis
T14434 24432-24435 CC denotes and
T14435 24436-24446 NN denotes immunoblot
T14436 24447-24455 NN denotes analysis
T14437 24456-24466 NN denotes Antibodies
T14438 24467-24474 IN denotes against
T14439 24475-24478 DT denotes the
T14440 24479-24484 JJ denotes human
T14441 24485-24498 NN denotes BMP-receptors
T14442 24499-24506 NN denotes Act-RIA
T14443 24506-24507 -COMMA- denotes ,
T14444 24508-24515 NN denotes BMP-RIB
T14445 24515-24516 -COMMA- denotes ,
T14446 24517-24524 NN denotes BMPR-II
T14447 24524-24525 -COMMA- denotes ,
T14448 24526-24534 NN denotes Act-RIIA
T14449 24535-24538 CC denotes and
T14450 24539-24547 NN denotes Act-RIIb
T14451 24548-24552 VB denotes were
T14452 24553-24562 VB denotes purchased
T14453 24563-24567 IN denotes from
T14454 24568-24569 NNP denotes R
T14455 24570-24571 CC denotes &
T14456 24572-24573 NNP denotes D
T14457 24574-24581 NNP denotes Systems
T14458 24582-24583 -LRB- denotes (
T14459 24583-24591 NNP denotes Abingdon
T14460 24591-24592 -COMMA- denotes ,
T14461 24593-24595 NNP denotes UK
T14462 24595-24596 -RRB- denotes )
T14463 24598-24607 NN denotes Detection
T14464 24608-24610 IN denotes of
T14465 24611-24614 DT denotes the
T14466 24615-24628 NN denotes BMP-6-protein
T14467 24629-24632 VB denotes has
T14468 24633-24637 VB denotes been
T14469 24638-24643 VB denotes tried
T14470 24644-24648 IN denotes with
T14471 24649-24652 DT denotes the
T14472 24653-24662 VB denotes following
T14473 24663-24673 NN denotes antibodies
T14474 24673-24674 -COLON- denotes :
T14475 24675-24679 NN denotes goat
T14476 24680-24690 JJ denotes polyclonal
T14477 24691-24701 NN denotes anti-BMP-6
T14478 24702-24703 -LRB- denotes (
T14479 24703-24708 NNP denotes Santa
T14480 24709-24713 NNP denotes Cruz
T14481 24713-24714 -COMMA- denotes ,
T14482 24715-24718 NNP denotes San
T14483 24719-24724 NNP denotes Diego
T14484 24724-24725 -COMMA- denotes ,
T14485 24726-24728 NNP denotes CA
T14486 24728-24729 -COMMA- denotes ,
T14487 24730-24733 NNP denotes USA
T14488 24733-24734 -RRB- denotes )
T14489 24734-24735 -COMMA- denotes ,
T14490 24736-24746 JJ denotes monoclonal
T14491 24747-24752 NN denotes mouse
T14492 24753-24763 NN denotes anti-BMP-6
T14493 24764-24767 CC denotes and
T14494 24768-24778 JJ denotes polyclonal
T14495 24779-24783 NN denotes goat
T14496 24784-24794 NN denotes anti-BMP-6
T14497 24795-24799 IN denotes from
T14498 24800-24801 NNP denotes R
T14499 24802-24803 CC denotes &
T14500 24804-24805 NNP denotes D
T14501 24806-24813 NNP denotes Systems
T14502 24814-24815 -LRB- denotes (
T14503 24815-24823 NNP denotes Abingdon
T14504 24823-24824 -COMMA- denotes ,
T14505 24825-24827 NNP denotes UK
T14506 24827-24828 -RRB- denotes )
T14507 24828-24829 -COMMA- denotes ,
T14508 24830-24833 CC denotes and
T14509 24834-24839 NN denotes mouse
T14510 24840-24850 JJ denotes monoclonal
T14511 24851-24861 JJ denotes anti-BMP-6
T14512 24862-24863 -LRB- denotes (
T14513 24863-24871 NNP denotes Chemicon
T14514 24872-24885 NNP denotes International
T14515 24886-24889 NNP denotes Inc
T14516 24889-24890 -COMMA- denotes ,
T14517 24891-24899 NNP denotes Temecula
T14518 24899-24900 -COMMA- denotes ,
T14519 24901-24903 NNP denotes CA
T14520 24903-24904 -COMMA- denotes ,
T14521 24905-24908 NNP denotes USA
T14522 24908-24909 -RRB- denotes )
T14523 24911-24927 NN denotes Characterisation
T14524 24928-24930 IN denotes of
T14525 24931-24945 JJ denotes BMP-signalling
T14526 24946-24954 NN denotes pathways
T14527 24955-24958 VB denotes was
T14528 24959-24963 VB denotes done
T14529 24964-24966 IN denotes by
T14530 24967-24970 NN denotes use
T14531 24971-24973 IN denotes of
T14532 24974-24992 NN denotes anti-phospho-Smad1
T14533 24992-24993 -COMMA- denotes ,
T14534 24994-24996 CD denotes -5
T14535 24996-24997 -COMMA- denotes ,
T14536 24998-25002 JJ denotes -and
T14537 25003-25004 CD denotes 8
T14538 25005-25015 JJ denotes polyclonal
T14539 25016-25024 NN denotes antibody
T14540 25025-25026 -LRB- denotes (
T14541 25026-25034 NNP denotes Chemicon
T14542 25034-25035 -COMMA- denotes ,
T14543 25036-25044 NNP denotes Temecula
T14544 25044-25045 -COMMA- denotes ,
T14545 25046-25048 NNP denotes CA
T14546 25048-25049 -COMMA- denotes ,
T14547 25050-25053 NNP denotes USA
T14548 25053-25054 -RRB- denotes )
T14549 25056-25066 NN denotes Expression
T14550 25067-25073 NN denotes levels
T14551 25074-25076 IN denotes of
T14552 25077-25082 NN denotes Id1–3
T14553 25083-25091 NN denotes proteins
T14554 25092-25096 VB denotes were
T14555 25097-25105 VB denotes detected
T14556 25106-25110 IN denotes with
T14557 25111-25121 JJ denotes polyclonal
T14558 25122-25128 NN denotes rabbit
T14559 25129-25137 NN denotes antibody
T14560 25138-25141 CC denotes and
T14561 25142-25151 NN denotes detection
T14562 25152-25155 VB denotes was
T14563 25156-25163 VB denotes blocked
T14564 25164-25168 IN denotes with
T14565 25169-25177 VB denotes blocking
T14566 25178-25185 NN denotes peptide
T14567 25186-25190 IN denotes from
T14568 25191-25196 NNP denotes Santa
T14569 25197-25201 NNP denotes Cruz
T14570 25202-25215 NNP denotes Biotechnology
T14571 25216-25217 -LRB- denotes (
T14572 25217-25222 NNP denotes Santa
T14573 25223-25227 NNP denotes Cruz
T14574 25227-25228 -COMMA- denotes ,
T14575 25229-25232 NNP denotes San
T14576 25233-25238 NNP denotes Diego
T14577 25238-25239 -COMMA- denotes ,
T14578 25240-25242 NNP denotes CA
T14579 25242-25243 -COMMA- denotes ,
T14580 25244-25247 NNP denotes USA
T14581 25247-25248 -RRB- denotes )
T14582 25250-25252 IN denotes As
T14583 25253-25262 JJ denotes secondary
T14584 25263-25273 NN denotes antibodies
T14585 25274-25280 VB denotes served
T14586 25281-25291 JJ denotes anti-mouse
T14587 25291-25292 -COMMA- denotes ,
T14588 25293-25302 JJ denotes anti-goat
T14589 25303-25305 CC denotes or
T14590 25306-25317 JJ denotes anti-rabbit
T14591 25318-25322 NN denotes IgG-
T14592 25323-25334 NN denotes horseradish
T14593 25335-25345 NN denotes peroxidase
T14594 25346-25347 -LRB- denotes (
T14595 25347-25350 NN denotes HRP
T14596 25350-25351 -RRB- denotes )
T14597 25352-25356 IN denotes from
T14598 25357-25371 NN denotes Dakocytomation
T14599 25372-25374 NN denotes AS
T14600 25375-25376 -LRB- denotes (
T14601 25376-25386 NN denotes Copenhagen
T14602 25386-25387 -COMMA- denotes ,
T14603 25388-25395 NNP denotes Denmark
T14604 25395-25396 -RRB- denotes )
T14605 25397-25400 IN denotes for
T14606 25401-25411 NN denotes immunoblot
T14607 25412-25420 NN denotes analysis
T14608 25422-25434 NN denotes Anti-β-actin
T14609 25435-25438 VB denotes was
T14610 25439-25443 IN denotes from
T14611 25444-25455 NNP denotes Santa-Cruz.
T14612 25456-25460 NNP denotes From
T14613 25461-25467 NNP denotes Becton
T14614 25468-25477 NNP denotes Dickinson
T14615 25478-25479 -LRB- denotes (
T14616 25479-25482 NNP denotes San
T14617 25483-25487 NNP denotes Jose
T14618 25487-25488 -COMMA- denotes ,
T14619 25489-25491 NNP denotes CA
T14620 25491-25492 -RRB- denotes )
T14621 25492-25493 -COMMA- denotes ,
T14622 25494-25496 PRP denotes we
T14623 25497-25506 VB denotes purchased
T14624 25507-25519 JJ denotes anti-CD19-PE
T14625 25519-25520 -COMMA- denotes ,
T14626 25521-25535 NN denotes anti-CD19-FITC
T14627 25537-25540 DT denotes The
T14628 25541-25551 NN denotes antibodies
T14629 25552-25556 VB denotes used
T14630 25557-25560 IN denotes for
T14631 25561-25565 NN denotes cell
T14632 25566-25573 NN denotes sorting
T14633 25574-25578 VB denotes were
T14634 25579-25588 JJ denotes anti-CD19
T14635 25589-25592 NN denotes PC5
T14636 25593-25597 IN denotes from
T14637 25598-25608 NNP denotes Immunotech
T14638 25609-25611 NNP denotes SA
T14639 25612-25613 -LRB- denotes (
T14640 25613-25622 NNP denotes Marseille
T14641 25622-25623 -COMMA- denotes ,
T14642 25624-25630 NNP denotes France
T14643 25630-25631 -RRB- denotes )
T14644 25632-25635 CC denotes and
T14645 25636-25645 JJ denotes anti-CD27
T14646 25646-25648 NN denotes PE
T14647 25649-25653 IN denotes from
T14648 25654-25660 NNP denotes Becton
T14649 25661-25670 NNP denotes Dickinson
T14650 25670-25671 -COMMA- denotes ,
T14651 25672-25683 NNP denotes Biosciences
T14652 25684-25694 NNP denotes Pharmingen
T14653 25695-25696 -LRB- denotes (
T14654 25696-25699 NNP denotes San
T14655 25700-25705 NNP denotes Diego
T14656 25705-25706 -COMMA- denotes ,
T14657 25707-25709 NNP denotes CA
T14658 25709-25710 -COMMA- denotes ,
T14659 25711-25714 NNP denotes USA
T14660 25714-25715 -RRB- denotes )
T15102 25718-25722 NN denotes Cell
T15103 25723-25730 NN denotes sorting
T15104 25731-25737 RB denotes Highly
T15105 25738-25746 VB denotes purified
T15106 25747-25757 JJ denotes CD19+CD27-
T15107 25758-25760 CC denotes or
T15108 25761-25771 JJ denotes CD19+CD27+
T15109 25772-25777 NN denotes cells
T15110 25778-25782 VB denotes were
T15111 25783-25791 VB denotes obtained
T15112 25792-25794 IN denotes by
T15113 25795-25803 VB denotes staining
T15114 25804-25809 JJ denotes CD19+
T15115 25810-25815 NN denotes cells
T15116 25816-25820 IN denotes with
T15117 25821-25830 JJ denotes anti-CD27
T15118 25831-25833 NN denotes PE
T15119 25834-25837 CC denotes and
T15120 25838-25842 NN denotes CD19
T15121 25843-25846 NN denotes PC5
T15122 25847-25851 NN denotes mAbs
T15123 25852-25855 IN denotes for
T15124 25856-25858 CD denotes 30
T15125 25859-25866 NN denotes minutes
T15126 25867-25869 IN denotes at
T15127 25870-25873 NN denotes 4°C
T15128 25873-25874 -COMMA- denotes ,
T15129 25875-25883 VB denotes followed
T15130 25884-25886 IN denotes by
T15131 25887-25894 VB denotes washing
T15132 25895-25899 IN denotes with
T15133 25900-25903 NNP denotes PBS
T15134 25904-25907 CC denotes and
T15135 25908-25915 VB denotes sorting
T15136 25916-25918 IN denotes on
T15137 25919-25923 NNP denotes FACS
T15138 25924-25928 NNP denotes DiVa
T15139 25929-25933 IN denotes from
T15140 25934-25940 NNP denotes Becton
T15141 25941-25950 NNP denotes Dickinson
T15269 25953-25965 JJ denotes Western-blot
T15270 25966-25974 NN denotes analysis
T15271 25975-25976 NN denotes B
T15272 25977-25982 NN denotes cells
T15273 25983-25987 IN denotes from
T15274 25988-25998 JJ denotes peripheral
T15275 25999-26004 NN denotes blood
T15276 26005-26007 CC denotes or
T15277 26008-26016 VB denotes cultured
T15278 26017-26027 NN denotes cell-lines
T15279 26028-26032 VB denotes were
T15280 26033-26038 VB denotes lysed
T15281 26039-26041 IN denotes in
T15282 26042-26047 NN denotes lysis
T15283 26048-26054 NN denotes buffer
T15284 26055-26056 -LRB- denotes (
T15285 26056-26064 NN denotes glycerol
T15286 26065-26067 CD denotes 10
T15287 26067-26068 NN denotes %
T15288 26068-26069 -COMMA- denotes ,
T15289 26070-26087 NN denotes β-mercaptoethanol
T15290 26088-26089 CD denotes 5
T15291 26089-26090 NN denotes %
T15292 26090-26091 -COMMA- denotes ,
T15293 26092-26098 CD denotes 0.0625
T15294 26099-26100 NN denotes M
T15295 26101-26109 NN denotes Tris-HCL
T15296 26110-26111 -LRB- denotes [
T15297 26111-26113 NN denotes pH
T15298 26114-26117 CD denotes 6.8
T15299 26117-26118 -RRB- denotes ]
T15300 26118-26119 -COMMA- denotes ,
T15301 26120-26126 NN denotes sodium
T15302 26127-26134 NN denotes dodecyl
T15303 26135-26143 NN denotes sulphate
T15304 26144-26145 -LRB- denotes [
T15305 26145-26148 NN denotes SDS
T15306 26148-26149 -RRB- denotes ]
T15307 26150-26153 CD denotes 2.5
T15308 26153-26154 NN denotes %
T15309 26154-26159 NN denotes w/vol
T15310 26159-26160 -RRB- denotes )
T15311 26162-26167 JJ denotes Total
T15312 26168-26175 NN denotes protein
T15313 26176-26177 -LRB- denotes (
T15314 26177-26183 CD denotes 30–100
T15315 26184-26186 NN denotes μg
T15316 26186-26187 -RRB- denotes )
T15317 26188-26192 IN denotes from
T15318 26193-26197 DT denotes each
T15319 26198-26204 NN denotes sample
T15320 26205-26208 VB denotes was
T15321 26209-26212 VB denotes run
T15322 26213-26215 IN denotes on
T15323 26216-26218 CD denotes 10
T15324 26218-26219 NN denotes %
T15325 26220-26222 CC denotes or
T15326 26223-26225 CD denotes 12
T15327 26225-26226 NN denotes %
T15328 26227-26245 NN denotes SDS/polyacrylamide
T15329 26246-26247 -LRB- denotes (
T15330 26247-26255 NN denotes SDS/PAGE
T15331 26255-26256 -RRB- denotes )
T15332 26257-26261 NN denotes gels
T15333 26262-26265 CC denotes and
T15334 26266-26273 VB denotes blotted
T15335 26274-26278 IN denotes onto
T15336 26279-26293 NN denotes nitrocellulose
T15337 26294-26301 NN denotes filters
T15338 26302-26303 -LRB- denotes (
T15339 26303-26310 NNP denotes Protran
T15340 26310-26311 -COLON- denotes ;
T15341 26312-26322 NNP denotes Schleicher
T15342 26323-26324 CC denotes &
T15343 26324-26331 NNP denotes Schuell
T15344 26332-26336 NNP denotes GmbH
T15345 26336-26337 -COMMA- denotes ,
T15346 26338-26344 NNP denotes Dassel
T15347 26344-26345 -COMMA- denotes ,
T15348 26346-26353 NNP denotes Germany
T15349 26353-26354 -RRB- denotes )
T15350 26356-26364 NN denotes Blocking
T15351 26364-26365 -COMMA- denotes ,
T15352 26366-26373 NN denotes washing
T15353 26374-26377 CC denotes and
T15354 26378-26388 NN denotes incubation
T15355 26389-26391 IN denotes of
T15356 26392-26395 DT denotes the
T15357 26396-26403 NN denotes filters
T15358 26404-26408 IN denotes with
T15359 26409-26416 JJ denotes primary
T15360 26417-26427 NN denotes antibodies
T15361 26428-26432 VB denotes were
T15362 26433-26437 VB denotes done
T15363 26438-26447 VB denotes according
T15364 26448-26450 TO denotes to
T15365 26451-26454 DT denotes the
T15366 26455-26467 NN denotes manufacturer
T15367 26467-26469 POS denotes 's
T15368 26470-26479 NN denotes protocols
T15369 26480-26482 IN denotes at
T15370 26483-26487 NN denotes room
T15371 26488-26499 NN denotes temperature
T15372 26500-26501 -LRB- denotes (
T15373 26501-26503 NN denotes RT
T15374 26503-26504 -RRB- denotes )
T15375 26506-26511 IN denotes After
T15376 26512-26519 VB denotes washing
T15377 26520-26524 IN denotes with
T15378 26525-26532 NN denotes TBS/0.1
T15379 26532-26533 NN denotes %
T15380 26534-26542 CD denotes Tween-20
T15381 26543-26544 -LRB- denotes (
T15382 26544-26549 NN denotes TBS-T
T15383 26549-26550 -RRB- denotes )
T15384 26550-26551 -COMMA- denotes ,
T15385 26552-26555 DT denotes the
T15386 26556-26563 NN denotes filters
T15387 26564-26568 VB denotes were
T15388 26569-26578 VB denotes incubated
T15389 26579-26583 IN denotes with
T15390 26584-26595 NN denotes horseradish
T15391 26596-26606 NN denotes peroxidase
T15392 26607-26608 -LRB- denotes (
T15393 26608-26611 NN denotes HRP
T15394 26611-26612 -RRB- denotes )
T15395 26613-26620 VB denotes coupled
T15396 26621-26623 TO denotes to
T15397 26624-26632 JJ denotes relevant
T15398 26633-26642 JJ denotes secondary
T15399 26643-26653 NN denotes antibodies
T15400 26654-26655 -LRB- denotes (
T15401 26655-26658 VB denotes see
T15402 26659-26664 IN denotes above
T15403 26664-26665 -RRB- denotes )
T15404 26666-26669 IN denotes for
T15405 26670-26672 CD denotes 60
T15406 26673-26680 NN denotes minutes
T15407 26681-26683 IN denotes at
T15408 26684-26686 NN denotes RT
T15409 26688-26694 NN denotes Enzyme
T15410 26695-26703 NN denotes activity
T15411 26704-26707 VB denotes was
T15412 26708-26718 VB denotes visualised
T15413 26719-26721 IN denotes by
T15414 26722-26725 DT denotes the
T15415 26726-26734 VB denotes enhanced
T15416 26735-26752 NN denotes chemiluminescence
T15417 26753-26759 NN denotes system
T15418 26759-26760 -COMMA- denotes ,
T15419 26761-26769 NN denotes ECL+PLUS
T15420 26770-26771 -LRB- denotes (
T15421 26771-26779 NNP denotes Amersham
T15422 26779-26780 -COMMA- denotes ,
T15423 26781-26796 NNP denotes Buckinghamshire
T15424 26796-26797 -COMMA- denotes ,
T15425 26798-26800 NNP denotes UK
T15426 26800-26801 -RRB- denotes )
T15427 26803-26816 JJ denotes Densitometric
T15428 26817-26825 NN denotes analysis
T15429 26826-26829 VB denotes was
T15430 26830-26839 VB denotes performed
T15431 26840-26842 IN denotes by
T15432 26843-26851 VB denotes scanning
T15433 26852-26862 NN denotes hyperfilms
T15434 26863-26865 IN denotes on
T15435 26866-26867 DT denotes a
T15436 26868-26876 NNP denotes Personal
T15437 26877-26889 NNP denotes Densitometer
T15438 26890-26892 NNP denotes SI
T15439 26893-26894 -LRB- denotes (
T15440 26894-26903 NNP denotes Molecular
T15441 26904-26912 NNP denotes Dynamics
T15442 26912-26913 -COMMA- denotes ,
T15443 26914-26923 NNP denotes Sunnyvale
T15444 26923-26924 -COMMA- denotes ,
T15445 26925-26927 NNP denotes CA
T15446 26927-26928 -RRB- denotes )
T15447 26930-26944 NN denotes Quantification
T15448 26945-26947 IN denotes of
T15449 26948-26951 NN denotes Id1
T15450 26951-26952 -COMMA- denotes ,
T15451 26953-26956 NN denotes Id2
T15452 26957-26960 CC denotes and
T15453 26961-26964 NN denotes Id3
T15454 26965-26972 NN denotes protein
T15455 26973-26976 VB denotes was
T15456 26977-26987 VB denotes calculated
T15457 26988-26990 IN denotes by
T15458 26991-27002 VB denotes normalizing
T15459 27003-27006 DT denotes the
T15460 27007-27015 JJ denotes specific
T15461 27016-27023 NN denotes protein
T15462 27024-27029 NN denotes bands
T15463 27030-27032 TO denotes to
T15464 27033-27040 NN denotes β-actin
T15465 27041-27046 VB denotes using
T15466 27047-27052 NN denotes Image
T15467 27053-27058 JJ denotes Quant
T15468 27059-27062 CD denotes 5.5
T15469 27063-27071 NN denotes software
T15470 27072-27073 -LRB- denotes (
T15471 27073-27082 NNP denotes Molecular
T15472 27083-27091 NNP denotes Dynamics
T15473 27091-27092 -RRB- denotes )
T15608 27095-27103 NN denotes Analysis
T15609 27104-27106 IN denotes of
T15610 27107-27112 NN denotes BMP-6
T15611 27113-27122 NN denotes messenger
T15612 27123-27126 NN denotes RNA
T15613 27127-27128 -LRB- denotes (
T15614 27128-27132 NN denotes mRNA
T15615 27132-27133 -RRB- denotes )
T15616 27134-27144 NN denotes expression
T15617 27145-27155 JJ denotes Endogenous
T15618 27156-27166 NN denotes expression
T15619 27167-27169 IN denotes of
T15620 27170-27173 DT denotes the
T15621 27174-27179 NN denotes BMP-6
T15622 27180-27184 NN denotes gene
T15623 27185-27188 VB denotes was
T15624 27189-27197 VB denotes examined
T15625 27198-27200 IN denotes by
T15626 27201-27208 JJ denotes reverse
T15627 27209-27233 NN denotes transcription-polymerase
T15628 27234-27239 NN denotes chain
T15629 27240-27248 NN denotes reaction
T15630 27250-27255 JJ denotes Total
T15631 27256-27259 NN denotes RNA
T15632 27260-27263 VB denotes was
T15633 27264-27272 VB denotes isolated
T15634 27273-27278 VB denotes using
T15635 27279-27289 RB denotes Absolutely
T15636 27290-27294 NNP denotes RNA™
T15637 27295-27301 NN denotes RT-PCR
T15638 27302-27310 NNP denotes Miniprep
T15639 27311-27314 NN denotes Kit
T15640 27315-27316 -LRB- denotes (
T15641 27316-27326 NNP denotes Stratagene
T15642 27327-27333 NNP denotes Europe
T15643 27333-27334 -COMMA- denotes ,
T15644 27335-27344 NNP denotes Amsterdam
T15645 27344-27345 -COMMA- denotes ,
T15646 27346-27356 NNP denotes Netherland
T15647 27356-27357 -RRB- denotes )
T15648 27358-27367 VB denotes according
T15649 27368-27370 TO denotes to
T15650 27371-27374 DT denotes the
T15651 27375-27388 NN denotes manufacturers
T15652 27389-27401 NN denotes instructions
T15653 27403-27417 NN denotes Quantification
T15654 27418-27420 IN denotes of
T15655 27421-27424 DT denotes the
T15656 27425-27433 VB denotes isolated
T15657 27434-27439 JJ denotes total
T15658 27440-27443 NN denotes RNA
T15659 27444-27447 VB denotes was
T15660 27448-27456 VB denotes achieved
T15661 27457-27459 IN denotes by
T15662 27460-27465 VB denotes using
T15663 27466-27484 JJ denotes spectrophotometric
T15664 27485-27490 NN denotes OD260
T15665 27491-27503 NN denotes measurements
T15666 27505-27510 JJ denotes Equal
T15667 27511-27518 NN denotes amounts
T15668 27519-27521 IN denotes of
T15669 27522-27525 NN denotes RNA
T15670 27526-27530 VB denotes were
T15671 27531-27535 RB denotes then
T15672 27536-27543 VB denotes reverse
T15673 27544-27555 VB denotes transcribed
T15674 27556-27558 TO denotes to
T15675 27559-27563 NN denotes cDNA
T15676 27564-27568 IN denotes with
T15677 27569-27576 NNP denotes TaqMan®
T15678 27577-27584 NNP denotes Reverse
T15679 27585-27598 NN denotes Transcription
T15680 27599-27607 NN denotes Reagents
T15681 27608-27609 -LRB- denotes (
T15682 27609-27616 NNP denotes Applied
T15683 27617-27627 NNP denotes Biosystems
T15684 27627-27628 -COMMA- denotes ,
T15685 27629-27635 NNP denotes Foster
T15686 27636-27640 NNP denotes City
T15687 27640-27641 -COMMA- denotes ,
T15688 27642-27644 NNP denotes CA
T15689 27644-27645 -COMMA- denotes ,
T15690 27646-27651 NN denotes U.S.A
T15691 27651-27652 -RRB- denotes )
T15692 27654-27656 TO denotes To
T15693 27657-27664 VB denotes measure
T15694 27665-27669 NN denotes mRNA
T15695 27670-27680 NN denotes expression
T15696 27681-27683 IN denotes of
T15697 27684-27688 NN denotes BMP6
T15698 27688-27689 -COMMA- denotes ,
T15699 27690-27697 NN denotes Id1–Id4
T15700 27698-27701 CC denotes and
T15701 27702-27706 NN denotes PGK1
T15702 27707-27710 NN denotes PCR
T15703 27711-27715 VB denotes were
T15704 27716-27723 VB denotes carried
T15705 27724-27727 RP denotes out
T15706 27728-27732 IN denotes with
T15707 27733-27740 NNP denotes TaqMan®
T15708 27741-27750 JJ denotes universal
T15709 27751-27757 NN denotes master
T15710 27758-27761 NN denotes mix
T15711 27763-27770 NN denotes Primers
T15712 27771-27774 CC denotes and
T15713 27775-27781 NN denotes probes
T15714 27782-27786 VB denotes were
T15715 27787-27795 VB denotes provided
T15716 27796-27798 IN denotes by
T15717 27799-27814 NN denotes Assay-on-Demand
T15718 27815-27816 -LRB- denotes (
T15719 27816-27823 NNP denotes Applied
T15720 27824-27834 NNP denotes Biosystems
T15721 27834-27835 -RRB- denotes )
T15722 27837-27840 NN denotes PCR
T15723 27841-27850 NN denotes reactions
T15724 27851-27855 VB denotes were
T15725 27856-27863 VB denotes carried
T15726 27864-27867 RP denotes out
T15727 27868-27870 IN denotes in
T15728 27871-27872 DT denotes a
T15729 27873-27878 JJ denotes final
T15730 27879-27885 NN denotes volume
T15731 27886-27888 IN denotes of
T15732 27889-27891 CD denotes 25
T15733 27892-27894 NN denotes μl
T15734 27895-27896 -LRB- denotes (
T15735 27896-27901 NN denotes BMP-6
T15736 27901-27902 -RRB- denotes )
T15737 27903-27905 CC denotes or
T15738 27906-27908 CD denotes 20
T15739 27909-27911 NN denotes μl
T15740 27912-27913 -LRB- denotes (
T15741 27913-27916 NN denotes ID1
T15742 27916-27917 -RRB- denotes )
T15743 27919-27922 DT denotes The
T15744 27923-27927 NN denotes cDNA
T15745 27928-27933 VB denotes added
T15746 27934-27936 TO denotes to
T15747 27937-27941 DT denotes each
T15748 27942-27950 NN denotes reaction
T15749 27951-27954 VB denotes was
T15750 27955-27965 JJ denotes equivalent
T15751 27966-27968 TO denotes to
T15752 27969-27972 DT denotes the
T15753 27973-27978 NN denotes input
T15754 27979-27981 IN denotes of
T15755 27982-27984 CD denotes 20
T15756 27985-27987 NN denotes ng
T15757 27988-27990 IN denotes of
T15758 27991-27996 JJ denotes total
T15759 27997-28000 NN denotes RNA
T15760 28002-28005 DT denotes The
T15761 28006-28010 NN denotes gene
T15762 28011-28021 NN denotes expression
T15763 28022-28025 VB denotes was
T15764 28026-28036 VB denotes quantified
T15765 28037-28042 VB denotes using
T15766 28043-28046 DT denotes the
T15767 28047-28055 JJ denotes standard
T15768 28056-28061 NN denotes curve
T15769 28062-28068 NN denotes method
T15770 28069-28070 -LRB- denotes (
T15771 28070-28074 NN denotes BMP6
T15772 28074-28075 -RRB- denotes )
T15773 28075-28076 -COMMA- denotes ,
T15774 28077-28079 CC denotes or
T15775 28080-28083 DT denotes the
T15776 28084-28095 JJ denotes comparative
T15777 28096-28098 NN denotes CT
T15778 28099-28105 NN denotes method
T15779 28106-28107 -LRB- denotes (
T15780 28107-28110 NN denotes Id1
T15781 28110-28111 -RRB- denotes )
T15782 28112-28114 IN denotes as
T15783 28115-28124 VB denotes described
T15784 28125-28127 IN denotes in
T15785 28128-28135 NNP denotes ABI7700
T15786 28136-28140 NNP denotes User
T15787 28141-28149 NNP denotes Bulletin
T15788 28150-28151 CD denotes 2
T15789 28152-28153 -LRB- denotes (
T15790 28153-28160 NNP denotes Applied
T15791 28161-28171 NNP denotes Biosystems
T15792 28171-28172 -RRB- denotes )
T15793 28174-28177 DT denotes The
T15794 28178-28188 NN denotes expression
T15795 28189-28192 VB denotes was
T15796 28193-28197 RB denotes then
T15797 28198-28208 VB denotes normalized
T15798 28209-28211 TO denotes to
T15799 28212-28215 DT denotes the
T15800 28216-28226 NN denotes expression
T15801 28227-28232 NN denotes level
T15802 28233-28235 IN denotes of
T15803 28236-28240 NN denotes PGK1
T15804 28242-28246 NN denotes PGK1
T15805 28247-28250 VB denotes was
T15806 28251-28257 VB denotes chosen
T15807 28257-28258 -COMMA- denotes ,
T15808 28259-28266 IN denotes because
T15809 28267-28269 PRP denotes it
T15810 28270-28273 VB denotes has
T15811 28274-28278 VB denotes been
T15812 28279-28284 VB denotes shown
T15813 28285-28287 TO denotes to
T15814 28288-28292 VB denotes have
T15815 28293-28296 JJ denotes low
T15816 28297-28307 NN denotes expression
T15817 28308-28319 NN denotes variability
T15818 28320-28325 IN denotes among
T15819 28326-28336 NN denotes lymphocyte
T15820 28337-28346 NN denotes specimens
T15821 28347-28348 -LRB- denotes [
T15822 28348-28350 CD denotes 56
T15823 28350-28351 -RRB- denotes ]
T15824 28353-28363 NN denotes Expression
T15825 28364-28370 NN denotes levels
T15826 28371-28373 IN denotes in
T15827 28374-28375 NN denotes B
T15828 28376-28381 NN denotes cells
T15829 28382-28386 VB denotes were
T15830 28387-28391 RB denotes then
T15831 28392-28399 VB denotes related
T15832 28400-28402 TO denotes to
T15833 28403-28406 DT denotes the
T15834 28407-28417 NN denotes expression
T15835 28418-28424 NN denotes levels
T15836 28425-28427 IN denotes in
T15837 28428-28433 NN denotes Ramos
T15838 28434-28439 NN denotes cells
T16237 28442-28446 NN denotes Cell
T16238 28447-28460 NN denotes proliferation
T16239 28461-28464 IN denotes For
T16240 28465-28475 NN denotes estimation
T16241 28476-28478 IN denotes of
T16242 28479-28482 NN denotes DNA
T16243 28483-28492 NN denotes synthesis
T16244 28492-28493 -COMMA- denotes ,
T16245 28494-28499 JJ denotes CD19+
T16246 28500-28505 NN denotes cells
T16247 28506-28507 -LRB- denotes (
T16248 28507-28510 CD denotes 7.5
T16249 28511-28512 CC denotes ×
T16250 28513-28516 CD denotes 104
T16251 28517-28526 NN denotes cells/0.2
T16252 28527-28529 NN denotes ml
T16253 28529-28530 -RRB- denotes )
T16254 28531-28533 CC denotes or
T16255 28534-28539 NN denotes Ramos
T16256 28540-28545 NN denotes cells
T16257 28546-28547 -LRB- denotes (
T16258 28547-28548 CD denotes 1
T16259 28549-28550 NN denotes ×
T16260 28551-28554 CD denotes 104
T16261 28555-28564 NN denotes cells/0.2
T16262 28565-28567 NN denotes ml
T16263 28567-28568 -RRB- denotes )
T16264 28569-28573 VB denotes were
T16265 28574-28582 VB denotes cultured
T16266 28583-28585 IN denotes in
T16267 28586-28596 NN denotes triplicate
T16268 28597-28599 IN denotes in
T16269 28600-28610 NN denotes microtiter
T16270 28611-28616 NN denotes wells
T16271 28618-28621 DT denotes The
T16272 28622-28627 NN denotes cells
T16273 28628-28632 VB denotes were
T16274 28633-28639 VB denotes pulsed
T16275 28640-28644 IN denotes with
T16276 28645-28648 CD denotes 3.7
T16277 28649-28650 CC denotes ×
T16278 28651-28656 NN denotes 104Bq
T16279 28657-28658 -LRB- denotes [
T16280 28658-28660 NN denotes 3H
T16281 28660-28661 -RRB- denotes ]
T16282 28661-28670 NN denotes thymidine
T16283 28671-28672 -LRB- denotes (
T16284 28672-28680 NNP denotes Amersham
T16285 28680-28681 -COMMA- denotes ,
T16286 28682-28697 NNP denotes Buckinghamshire
T16287 28697-28698 -COMMA- denotes ,
T16288 28699-28701 NNP denotes UK
T16289 28701-28702 -RRB- denotes )
T16290 28703-28706 IN denotes for
T16291 28707-28710 DT denotes the
T16292 28711-28715 JJ denotes last
T16293 28716-28718 CD denotes 16
T16294 28719-28720 NN denotes h
T16295 28721-28723 IN denotes of
T16296 28724-28725 DT denotes a
T16297 28726-28730 JJ denotes 72-h
T16298 28731-28741 NN denotes incubation
T16299 28743-28746 DT denotes The
T16300 28747-28752 NN denotes cells
T16301 28753-28757 VB denotes were
T16302 28758-28767 VB denotes harvested
T16303 28768-28773 VB denotes using
T16304 28774-28776 DT denotes an
T16305 28777-28786 VB denotes automated
T16306 28787-28791 NN denotes cell
T16307 28792-28801 NN denotes harvester
T16308 28802-28803 -LRB- denotes (
T16309 28803-28810 NNP denotes Packard
T16310 28811-28821 NNP denotes Instrument
T16311 28822-28829 NNP denotes Company
T16312 28829-28830 -COMMA- denotes ,
T16313 28831-28838 NNP denotes Meriden
T16314 28838-28839 -COMMA- denotes ,
T16315 28840-28842 NNP denotes CT
T16316 28842-28843 -COMMA- denotes ,
T16317 28844-28847 NNP denotes USA
T16318 28847-28848 -RRB- denotes )
T16319 28849-28852 CC denotes and
T16320 28853-28854 -LRB- denotes [
T16321 28854-28856 NN denotes 3H
T16322 28856-28857 -RRB- denotes ]
T16323 28857-28866 NN denotes thymidine
T16324 28867-28880 NN denotes incorporation
T16325 28881-28884 VB denotes was
T16326 28885-28895 VB denotes determined
T16327 28896-28898 IN denotes in
T16328 28899-28900 DT denotes a
T16329 28901-28914 NN denotes scintillation
T16330 28915-28922 NN denotes counter
T16331 28923-28924 -LRB- denotes (
T16332 28924-28932 NNP denotes TopCount
T16333 28932-28933 -COMMA- denotes ,
T16334 28934-28941 NNP denotes Packard
T16335 28942-28952 NNP denotes Instrument
T16336 28953-28960 NNP denotes Company
T16337 28961-28965 NNP denotes Inc.
T16338 28965-28966 -COMMA- denotes ,
T16339 28967-28974 NNP denotes Meriden
T16340 28974-28975 -COMMA- denotes ,
T16341 28976-28978 NN denotes CT
T16342 28978-28979 -RRB- denotes )
T16481 28982-28995 NN denotes Determination
T16482 28996-28998 IN denotes of
T16483 28999-29003 NN denotes cell
T16484 29004-29009 NN denotes death
T16485 29010-29014 NN denotes Cell
T16486 29015-29020 NN denotes death
T16487 29021-29024 VB denotes was
T16488 29025-29033 VB denotes measured
T16489 29034-29036 IN denotes by
T16490 29037-29042 JJ denotes vital
T16491 29043-29046 NN denotes dye
T16492 29047-29056 NN denotes exclusion
T16493 29057-29061 NN denotes test
T16494 29062-29064 IN denotes by
T16495 29065-29073 VB denotes staining
T16496 29074-29079 NN denotes cells
T16497 29080-29084 IN denotes with
T16498 29085-29086 CD denotes 5
T16499 29087-29092 NN denotes μg/ml
T16500 29093-29102 NN denotes propidium
T16501 29103-29109 NN denotes iodide
T16502 29110-29111 -LRB- denotes (
T16503 29111-29112 -LRB- denotes [
T16504 29112-29114 NNP denotes PI
T16505 29114-29115 -RRB- denotes ]
T16506 29115-29116 -COLON- denotes ;
T16507 29117-29127 NNP denotes Calbiochem
T16508 29128-29133 NNP denotes Corp.
T16509 29133-29134 -COLON- denotes ;
T16510 29135-29137 NNP denotes La
T16511 29138-29143 NNP denotes Jolla
T16512 29143-29144 -COMMA- denotes ,
T16513 29145-29147 NNP denotes CA
T16514 29147-29148 -COLON- denotes ;
T16515 29149-29150 CD denotes 5
T16516 29151-29156 NN denotes mg/ml
T16517 29156-29157 -RRB- denotes )
T16518 29158-29161 IN denotes for
T16519 29162-29165 CD denotes one
T16520 29166-29172 NN denotes minute
T16521 29173-29175 IN denotes on
T16522 29176-29179 NN denotes ice
T16523 29181-29183 IN denotes At
T16524 29184-29189 JJ denotes least
T16525 29190-29195 CD denotes 1,000
T16526 29196-29201 NN denotes cells
T16527 29202-29205 IN denotes per
T16528 29206-29212 NN denotes sample
T16529 29213-29217 VB denotes were
T16530 29218-29221 VB denotes run
T16531 29222-29224 IN denotes on
T16532 29225-29226 DT denotes a
T16533 29227-29229 NN denotes BD
T16534 29230-29241 NN denotes FACSCalibur
T16535 29242-29246 NN denotes flow
T16536 29247-29256 NN denotes cytometer
T16609 29259-29270 JJ denotes Statistical
T16610 29271-29279 NN denotes analysis
T16611 29280-29283 DT denotes The
T16612 29284-29295 JJ denotes statistical
T16613 29296-29308 NN denotes significance
T16614 29309-29311 IN denotes of
T16615 29312-29323 NN denotes differences
T16616 29324-29331 IN denotes between
T16617 29332-29338 NN denotes groups
T16618 29339-29342 VB denotes was
T16619 29343-29353 VB denotes determined
T16620 29354-29359 VB denotes using
T16621 29360-29363 DT denotes the
T16622 29364-29370 JJ denotes paired
T16623 29371-29381 JJ denotes two-tailed
T16624 29382-29390 NNP denotes Wilcoxon
T16625 29391-29404 JJ denotes nonparametric
T16626 29405-29409 NN denotes test
T16627 29409-29410 -COMMA- denotes ,
T16628 29411-29413 IN denotes by
T16629 29414-29422 VB denotes applying
T16630 29423-29431 NN denotes SPSS10.1
T16631 29432-29440 NN denotes software
T16632 29441-29442 -LRB- denotes (
T16633 29442-29446 NNP denotes SPSS
T16634 29447-29451 NNP denotes Inc.
T16635 29451-29452 -COMMA- denotes ,
T16636 29453-29460 NNP denotes Chicago
T16637 29460-29461 -COMMA- denotes ,
T16638 29462-29464 NNP denotes IL
T16639 29464-29465 -COMMA- denotes ,
T16640 29466-29469 NNP denotes USA
T16641 29469-29470 -RRB- denotes )
T16642 29472-29473 NN denotes P
T16643 29474-29480 NN denotes values
T16644 29481-29485 JJ denotes less
T16645 29486-29490 IN denotes than
T16646 29491-29495 CD denotes 0.05
T16647 29496-29500 VB denotes were
T16648 29501-29511 VB denotes considered
T16649 29512-29523 JJ denotes significant
R100 T223 T222 arg2Of proteins,secreted
R1000 T1295 T1293 arg2Of investigated,been
R1001 T1295 T1294 arg1Of investigated,widely
R1002 T1298 T1296 arg2Of respect,In
R1003 T1298 T1297 arg1Of respect,that
R1004 T1300 T1301 arg1Of BMP-,2
R1005 T1300 T1302 arg1Of BMP-,","
R1006 T1302 T1304 arg1Of ",",and
R1007 T1303 T1302 arg2Of -4,","
R1008 T1304 T1306 arg1Of and,have
R1009 T1304 T1307 arg1Of and,been
R101 T223 T224 arg1Of proteins,with
R1010 T1304 T1308 arg2Of and,found
R1011 T1304 T1310 arg1Of and,control
R1012 T1305 T1304 arg2Of -7,and
R1013 T1308 T1296 arg1Of found,In
R1014 T1308 T1299 arg1Of found,","
R1015 T1308 T1306 arg2Of found,have
R1016 T1308 T1307 arg2Of found,been
R1017 T1310 T1308 arg3Of control,found
R1018 T1310 T1309 arg1Of control,to
R1019 T1311 T1312 arg1Of differentiation,of
R102 T226 T224 arg2Of roles,with
R1020 T1311 T1319 arg1Of differentiation,and
R1021 T1315 T1312 arg2Of cells,of
R1022 T1315 T1313 arg1Of cells,hematopoietic
R1023 T1315 T1314 arg1Of cells,stem
R1024 T1315 T1316 arg1Of cells,[
R1025 T1317 T1316 arg2Of 5,[
R1026 T1318 T1316 arg3Of ],[
R1027 T1319 T1310 arg2Of and,control
R1028 T1323 T1319 arg2Of development,and
R1029 T1323 T1320 arg1Of development,early
R103 T226 T225 arg1Of roles,pleiotropic
R1030 T1323 T1321 arg1Of development,T
R1031 T1323 T1322 arg1Of development,cell
R1032 T1323 T1324 arg1Of development,[
R1033 T1325 T1324 arg2Of "6,7",[
R1034 T1326 T1324 arg3Of ],[
R1035 T1327 T1328 arg1Of BMP-6,has
R1036 T1327 T1329 arg1Of BMP-6,been
R1037 T1327 T1330 arg2Of BMP-6,reported
R1038 T1327 T1332 arg1Of BMP-6,reduce
R1039 T1330 T1328 arg2Of reported,has
R104 T231 T227 arg2Of types,in
R1040 T1330 T1329 arg2Of reported,been
R1041 T1332 T1330 arg3Of reduce,reported
R1042 T1332 T1331 arg1Of reduce,to
R10420 T13414 T13413 arg2Of conclusion,In
R10421 T13417 T13416 arg1Of results,our
R10422 T13417 T13418 arg1Of results,show
R10423 T13418 T13413 arg1Of show,In
R10424 T13418 T13415 arg1Of show,","
R10425 T13420 T13421 arg1Of BMP-6,induces
R10426 T13421 T13418 arg2Of induces,show
R10427 T13421 T13419 arg1Of induces,that
R10428 T13421 T13427 arg1Of induces,in
R10429 T13422 T13421 arg2Of activation,induces
R1043 T1334 T1332 arg2Of number,reduce
R10430 T13422 T13423 arg1Of activation,of
R10431 T13426 T13423 arg2Of signalling,of
R10432 T13426 T13424 arg1Of signalling,intracellular
R10433 T13426 T13425 arg1Of signalling,Smad
R10434 T13430 T13427 arg2Of B-cells,in
R10435 T13430 T13428 arg1Of B-cells,mature
R10436 T13430 T13429 arg1Of B-cells,human
R10437 T13430 T13431 arg1Of B-cells,with
R10438 T13433 T13431 arg2Of production,with
R10439 T13433 T13432 arg1Of production,consecutive
R1044 T1334 T1333 arg1Of number,the
R10440 T13433 T13434 arg1Of production,of
R10441 T13436 T13434 arg2Of protein,of
R10442 T13436 T13435 arg1Of protein,Id1
R10443 T13439 T13440 arg1Of we,report
R10444 T13440 T13437 arg1Of report,Furthermore
R10445 T13440 T13438 arg1Of report,","
R10446 T13442 T13443 arg1Of BMP-6,has
R10447 T13443 T13440 arg2Of has,report
R10448 T13443 T13441 arg1Of has,that
R10449 T13443 T13447 arg1Of has,in
R1045 T1334 T1335 arg1Of number,of
R10450 T13446 T13443 arg2Of effect,has
R10451 T13446 T13444 arg1Of effect,an
R10452 T13446 T13445 arg1Of effect,antiproliferative
R10453 T13449 T13447 arg2Of cells,in
R10454 T13449 T13448 arg1Of cells,B
R10455 T13449 T13450 arg2Of cells,stimulated
R10456 T13450 T13451 arg1Of stimulated,with
R10457 T13452 T13453 arg1Of anti-IgM,alone
R10458 T13452 T13454 arg1Of anti-IgM,or
R10459 T13454 T13451 arg2Of or,with
R1046 T1337 T1335 arg2Of cells,of
R10460 T13457 T13454 arg2Of action,or
R10461 T13457 T13455 arg1Of action,the
R10462 T13457 T13456 arg2Of action,combined
R10463 T13457 T13458 arg1Of action,of
R10464 T13459 T13460 arg1Of anti-IgM,and
R10465 T13460 T13458 arg2Of and,of
R10466 T13461 T13460 arg2Of CD40L,and
R10467 T13464 T13465 arg1Of BMP-6,induces
R10468 T13465 T13462 arg1Of induces,Additionally
R10469 T13465 T13463 arg1Of induces,","
R1047 T1337 T1336 arg1Of cells,cobblestone-area-forming
R10470 T13467 T13465 arg2Of death,induces
R10471 T13467 T13466 arg1Of death,cell
R10472 T13467 T13468 arg1Of death,in
R10473 T13472 T13469 arg2Of cells,activated
R10474 T13472 T13470 arg1Of cells,memory
R10475 T13472 T13471 arg1Of cells,B
R10476 T13472 T13473 arg1Of cells,and
R10477 T13473 T13468 arg2Of and,in
R10478 T13475 T13473 arg2Of cells,and
R10479 T13475 T13474 arg1Of cells,Ramos
R1048 T1337 T1338 arg1Of cells,of
R10480 T13476 T13477 arg1Of Taken,together
R10481 T13480 T13479 arg1Of results,these
R10482 T13480 T13481 arg1Of results,provide
R10483 T13481 T13476 modOf provide,Taken
R10484 T13481 T13478 arg1Of provide,","
R10485 T13483 T13481 arg2Of rationale,provide
R10486 T13483 T13482 arg1Of rationale,a
R10487 T13483 T13484 modOf rationale,to
R10488 T13486 T13484 arg1Of examine,to
R10489 T13486 T13485 arg1Of examine,further
R1049 T1342 T1338 arg2Of cells,of
R10490 T13488 T13486 arg2Of role,examine
R10491 T13488 T13487 arg1Of role,the
R10492 T13488 T13489 arg1Of role,of
R10493 T13488 T13492 arg1Of role,in
R10494 T13488 T13500 arg1Of role,in
R10495 T13491 T13489 arg2Of signalling,of
R10496 T13491 T13490 arg1Of signalling,BMP-6
R10497 T13492 T13499 arg1Of in,as
R10498 T13496 T13492 arg2Of biology,in
R10499 T13496 T13493 arg1Of biology,normal
R105 T231 T228 arg1Of types,many
R1050 T1342 T1339 arg1Of cells,normal
R10500 T13496 T13494 arg1Of biology,B
R10501 T13496 T13495 arg1Of biology,cell
R10502 T13499 T13497 arg1Of as,as
R10503 T13499 T13498 arg1Of as,well
R10504 T13500 T13499 arg2Of in,as
R10505 T13502 T13500 arg2Of conditions,in
R10506 T13502 T13501 arg1Of conditions,pathologic
R10507 T13502 T13503 arg1Of conditions,like
R10508 T13506 T13504 arg1Of malignancies,B
R10509 T13506 T13505 arg1Of malignancies,cell
R1051 T1342 T1340 arg1Of cells,human
R10510 T13506 T13507 arg1Of malignancies,and
R10511 T13507 T13503 arg2Of and,like
R10512 T13509 T13507 arg2Of disorders,and
R10513 T13509 T13508 arg1Of disorders,autoimmune
R1052 T1342 T1341 arg1Of cells,haematopoietic
R1053 T1342 T1343 arg1Of cells,[
R1054 T1344 T1343 arg2Of 8,[
R1055 T1345 T1343 arg3Of ],[
R1056 T1348 T1349 arg1Of BMP-2,","
R1057 T1349 T1351 arg1Of ",",","
R1058 T1350 T1349 arg2Of -4,","
R1059 T1351 T1353 arg1Of ",",and
R106 T231 T229 arg1Of types,different
R1060 T1352 T1351 arg2Of 6,","
R1061 T1353 T1355 arg1Of and,had
R1062 T1354 T1353 arg2Of -7,and
R1063 T1355 T1346 arg1Of had,Furthermore
R10633 T13709 T13708 arg1Of culture,Cell
R10634 T13712 T13710 arg2Of specified,If
R10635 T13712 T13711 arg1Of specified,not
R10636 T13715 T13712 arg2Of cells,specified
R10637 T13715 T13714 arg1Of cells,all
R10638 T13715 T13716 arg1Of cells,were
R10639 T13715 T13717 arg2Of cells,cultured
R1064 T1355 T1347 arg1Of had,","
R10640 T13717 T13710 arg1Of cultured,If
R10641 T13717 T13713 arg1Of cultured,","
R10642 T13717 T13716 arg2Of cultured,were
R10643 T13717 T13718 arg1Of cultured,in
R10644 T13719 T13720 arg1Of X-VIVO,15™
R10645 T13719 T13721 arg1Of X-VIVO,(
R10646 T13722 T13723 arg1Of BioWhittaker,","
R10647 T13723 T13721 arg2Of ",",(
R10648 T13723 T13725 arg1Of ",",","
R10649 T13723 T13726 arg1Of ",",Belgium
R1065 T1355 T1362 arg1Of had,on
R10650 T13724 T13723 arg2Of Verviers,","
R10651 T13727 T13721 arg3Of ),(
R10652 T13729 T13718 arg2Of medium,in
R10653 T13729 T13719 arg1Of medium,X-VIVO
R10654 T13729 T13728 arg1Of medium,serum-free
R10655 T13729 T13730 arg1Of medium,at
R10656 T13731 T13732 arg1Of 37°C,and
R10657 T13732 T13730 arg2Of and,at
R10658 T13732 T13736 arg1Of and,in
R10659 T13733 T13734 arg1Of 5,%
R1066 T1357 T1358 arg1Of antiproliferative,and
R10660 T13735 T13732 arg2Of CO2,and
R10661 T13735 T13733 arg1Of CO2,5
R10662 T13737 T13736 arg2Of air,in
R10663 T13739 T13738 arg1Of blood,Peripheral
R10664 T13739 T13740 arg1Of blood,was
R10665 T13739 T13741 arg2Of blood,provided
R10666 T13741 T13740 arg2Of provided,was
R10667 T13741 T13750 arg1Of provided,with
R10668 T13745 T13741 arg1Of Bank,provided
R10669 T13745 T13742 arg2Of Bank,by
R1067 T1360 T1358 arg2Of proapoptotic,and
R10670 T13745 T13743 arg1Of Bank,the
R10671 T13745 T13744 arg1Of Bank,Blood
R10672 T13745 T13746 arg1Of Bank,at
R10673 T13749 T13746 arg2Of Hospital,at
R10674 T13749 T13747 arg1Of Hospital,Buskerud
R10675 T13749 T13748 arg1Of Hospital,Regional
R10676 T13752 T13750 arg2Of agreement,with
R10677 T13752 T13751 arg1Of agreement,formal
R10678 T13752 T13753 arg1Of agreement,by
R10679 T13755 T13757 arg1Of patients,and
R1068 T1360 T1359 arg1Of proapoptotic,a
R10680 T13757 T13753 arg2Of and,by
R10681 T13757 T13754 arg1Of and,the
R10682 T13757 T13756 arg1Of and,","
R10683 T13757 T13759 arg1Of and,by
R10684 T13758 T13757 arg2Of approval,and
R10685 T13763 T13759 arg2Of committee,by
R10686 T13763 T13760 arg1Of committee,the
R10687 T13763 T13761 arg1Of committee,regional
R10688 T13763 T13762 arg1Of committee,ethics
R10689 T13765 T13764 arg1Of purified,Highly
R1069 T1361 T1355 arg2Of effect,had
R10690 T13768 T13765 arg1Of B-lymphocytes,purified
R10691 T13768 T13766 arg1Of B-lymphocytes,resting
R10692 T13768 T13767 arg1Of B-lymphocytes,human
R10693 T13768 T13769 arg1Of B-lymphocytes,(
R10694 T13768 T13773 arg1Of B-lymphocytes,were
R10695 T13768 T13774 arg2Of B-lymphocytes,isolated
R10696 T13768 T13780 arg1Of B-lymphocytes,rosetting
R10697 T13771 T13769 arg2Of cells,(
R10698 T13771 T13770 arg1Of cells,CD19+
R10699 T13772 T13769 arg3Of ),(
R107 T231 T230 arg1Of types,cell
R1070 T1361 T1356 arg1Of effect,an
R10700 T13774 T13773 arg2Of isolated,were
R10701 T13774 T13775 arg1Of isolated,from
R10702 T13774 T13779 arg1Of isolated,by
R10703 T13778 T13775 arg2Of blood,from
R10704 T13778 T13776 arg1Of blood,the
R10705 T13778 T13777 arg1Of blood,peripheral
R10706 T13780 T13779 arg2Of rosetting,by
R10707 T13780 T13781 arg1Of rosetting,with
R10708 T13780 T13794 arg1Of rosetting,as
R10709 T13780 T13796 arg1Of rosetting,[
R1071 T1361 T1357 arg1Of effect,antiproliferative
R10710 T13783 T13781 arg2Of beads,with
R10711 T13783 T13782 arg1Of beads,immunomagnetic
R10712 T13783 T13784 arg1Of beads,(
R10713 T13786 T13787 arg1Of M450,;
R10714 T13787 T13784 arg2Of ;,(
R10715 T13787 T13785 arg1Of ;,Dynabeads
R10716 T13787 T13791 arg1Of ;,","
R10717 T13787 T13792 arg1Of ;,Norway
R10718 T13788 T13789 arg1Of Dynal,","
R10719 T13789 T13787 arg2Of ",",;
R1072 T1361 T1360 arg1Of effect,proapoptotic
R10720 T13790 T13789 arg2Of Oslo,","
R10721 T13793 T13784 arg3Of ),(
R10722 T13795 T13794 arg2Of described,as
R10723 T13797 T13796 arg2Of 55,[
R10724 T13798 T13796 arg3Of ],[
R10725 T13800 T13799 arg1Of procedure,This
R10726 T13800 T13801 arg1Of procedure,yields
R10727 T13801 T13818 arg1Of yields,as
R10728 T13802 T13803 arg1Of less,than
R10729 T13802 T13805 arg1Of less,%
R1073 T1365 T1362 arg2Of cells,on
R10730 T13804 T13803 arg2Of 0.5,than
R10731 T13807 T13802 arg1Of cells,less
R10732 T13807 T13806 arg1Of cells,T
R10733 T13807 T13808 arg1Of cells,","
R10734 T13808 T13814 arg1Of ",",and
R10735 T13809 T13810 arg1Of 0.1,%
R10736 T13812 T13808 arg2Of cells,","
R10737 T13812 T13809 arg1Of cells,0.1
R10738 T13812 T13811 arg1Of cells,NK
R10739 T13814 T13801 arg2Of and,yields
R1074 T1365 T1363 arg1Of cells,multiple
R10740 T13814 T13813 arg1Of and,","
R10741 T13815 T13816 arg1Of 0.5,%
R10742 T13817 T13814 arg2Of monocytes,and
R10743 T13817 T13815 arg1Of monocytes,0.5
R10744 T13819 T13818 arg2Of judged,as
R10745 T13823 T13819 arg1Of staining,judged
R10746 T13823 T13820 arg2Of staining,by
R10747 T13823 T13821 arg1Of staining,indirect
R10748 T13823 T13822 arg1Of staining,immunofluorescence
R10749 T13827 T13824 arg1Of lines,The
R1075 T1365 T1364 arg1Of cells,myeloma
R10750 T13827 T13825 arg1Of lines,following
R10751 T13827 T13826 arg1Of lines,cell
R10752 T13827 T13828 arg1Of lines,from
R10753 T13827 T13832 arg1Of lines,were
R10754 T13827 T13833 arg2Of lines,maintained
R10755 T13827 T13870 arg1Of lines,serum-starved
R10756 T13827 T13877 arg2Of lines,cultured
R10757 T13827 T13882 arg1Of lines,included
R10758 T13831 T13828 arg2Of malignancies,from
R10759 T13831 T13829 arg1Of malignancies,human
R1076 T1365 T1366 arg1Of cells,[
R10760 T13831 T13830 arg1Of malignancies,lymphoid
R10761 T13833 T13834 arg1Of maintained,in
R10762 T13833 T13869 arg1Of maintained,but
R10763 T13835 T13834 arg2Of RPMI,in
R10764 T13835 T13836 arg1Of RPMI,1640
R10765 T13835 T13837 arg1Of RPMI,(
R10766 T13835 T13846 arg2Of RPMI,supplemented
R10767 T13840 T13837 arg2Of GmbH,(
R10768 T13840 T13838 arg1Of GmbH,PAA
R10769 T13840 T13839 arg1Of GmbH,Laboratories
R1077 T1367 T1366 arg2Of 9-11,[
R10770 T13840 T13841 arg1Of GmbH,","
R10771 T13842 T13841 arg2Of Pasching,","
R10772 T13842 T13843 arg1Of Pasching,","
R10773 T13842 T13844 arg1Of Pasching,Austria
R10774 T13845 T13837 arg3Of ),(
R10775 T13846 T13847 arg1Of supplemented,with
R10776 T13848 T13849 arg1Of 10,%
R10777 T13852 T13848 arg1Of serum,10
R10778 T13852 T13850 arg1Of serum,foetal
R10779 T13852 T13851 arg1Of serum,bovine
R1078 T1368 T1366 arg3Of ],[
R10780 T13852 T13853 arg1Of serum,(
R10781 T13852 T13856 arg1Of serum,","
R10782 T13854 T13853 arg2Of FCS,(
R10783 T13855 T13853 arg3Of ),(
R10784 T13856 T13862 arg1Of ",",and
R10785 T13860 T13856 arg2Of G,","
R10786 T13860 T13857 arg1Of G,100
R10787 T13860 T13858 arg1Of G,units/ml
R10788 T13860 T13859 arg1Of G,penicillin
R10789 T13862 T13847 arg2Of and,with
R1079 T1370 T1369 arg2Of addition,In
R10790 T13862 T13861 arg1Of and,","
R10791 T13864 T13862 arg2Of units/ml,and
R10792 T13864 T13863 arg1Of units/ml,100
R10793 T13864 T13865 arg1Of units/ml,of
R10794 T13867 T13865 arg2Of sulphate,of
R10795 T13867 T13866 arg1Of sulphate,streptomycin
R10796 T13869 T13868 arg1Of but,","
R10797 T13869 T13871 arg1Of but,for
R10798 T13869 T13876 arg1Of but,and
R10799 T13870 T13869 arg2Of serum-starved,but
R108 T234 T232 arg1Of role,A
R1080 T1375 T1372 arg2Of profiling,by
R10800 T13874 T13872 arg1Of four,at
R10801 T13874 T13873 arg1Of four,least
R10802 T13875 T13871 arg2Of hours,for
R10803 T13875 T13874 arg1Of hours,four
R10804 T13876 T13832 arg2Of and,were
R10805 T13876 T13881 arg1Of and,when
R10806 T13877 T13876 arg2Of cultured,and
R10807 T13877 T13878 arg1Of cultured,in
R10808 T13879 T13878 arg2Of X-VIVO,in
R10809 T13879 T13880 arg1Of X-VIVO,15™
R1081 T1375 T1373 arg1Of profiling,gene
R10810 T13882 T13881 arg2Of included,when
R10811 T13882 T13883 arg1Of included,in
R10812 T13884 T13883 arg2Of experiments,in
R10813 T13884 T13885 arg1Of experiments,:
R10814 T13890 T13886 arg1Of Ramos,EBV-negative
R10815 T13890 T13887 arg1Of Ramos,BL
R10816 T13890 T13888 arg1Of Ramos,cell
R10817 T13890 T13889 arg1Of Ramos,lines
R10818 T13890 T13891 arg1Of Ramos,(
R10819 T13890 T13895 arg1Of Ramos,","
R1082 T1375 T1374 arg1Of profiling,expression
R10820 T13892 T13891 arg2Of ECACC,(
R10821 T13892 T13893 arg1Of ECACC,85030802
R10822 T13894 T13891 arg3Of ),(
R10823 T13895 T13882 arg2Of ",",included
R10824 T13896 T13895 arg2Of HL60,","
R10825 T13896 T13897 arg1Of HL60,(
R10826 T13898 T13897 arg2Of JCRB0085,(
R10827 T13899 T13897 arg3Of ),(
R1083 T1377 T1379 arg1Of BMP-6,increased
R1084 T1377 T1389 arg1Of BMP-6,was
R1085 T1377 T1390 arg2Of BMP-6,associated
R1086 T1379 T1388 arg1Of increased,and
R1087 T1382 T1379 arg2Of value,increased
R1088 T1382 T1380 arg1Of value,the
R1089 T1382 T1381 arg1Of value,predictive
R109 T234 T233 arg1Of role,potential
R1090 T1382 T1383 arg1Of value,for
R1091 T1387 T1383 arg2Of test,for
R1092 T1387 T1384 arg1Of test,a
R1093 T1387 T1385 arg1Of test,multi-gene
R1094 T1387 T1386 arg1Of test,signature
R1095 T1388 T1369 arg1Of and,In
R1096 T1388 T1371 arg1Of and,","
R1097 T1388 T1372 arg1Of and,by
R1098 T1388 T1376 arg1Of and,","
R1099 T1388 T1378 arg1Of and,significantly
R110 T234 T235 arg1Of role,of
R1100 T1390 T1388 arg2Of associated,and
R1101 T1390 T1389 arg2Of associated,was
R1102 T1390 T1391 arg1Of associated,with
R1103 T1390 T1404 arg1Of associated,[
R1104 T1394 T1391 arg2Of outcome,with
R1105 T1394 T1392 arg1Of outcome,a
R1106 T1394 T1393 arg1Of outcome,poor
R1107 T1394 T1395 arg1Of outcome,in
R1108 T1400 T1395 arg2Of lymphomas,in
R1109 T1400 T1396 arg1Of lymphomas,diffuse
R111 T234 T237 arg1Of role,in
R1110 T1400 T1397 arg1Of lymphomas,large
R1111 T1400 T1398 arg1Of lymphomas,B
R1112 T1400 T1399 arg1Of lymphomas,cell
R1113 T1400 T1401 arg1Of lymphomas,(
R1114 T1402 T1401 arg2Of DLBCL,(
R1115 T1403 T1401 arg3Of ),(
R1116 T1405 T1404 arg2Of 12,[
R11164 T14428 T14429 arg2Of Antibodies,used
R11165 T14429 T14430 arg1Of used,for
R11166 T14433 T14431 arg1Of analysis,flow
R11167 T14433 T14432 arg1Of analysis,cytometric
R11168 T14433 T14434 arg1Of analysis,and
R11169 T14434 T14430 arg2Of and,for
R1117 T1406 T1404 arg3Of ],[
R11170 T14436 T14434 arg2Of analysis,and
R11171 T14436 T14435 arg1Of analysis,immunoblot
R11172 T14437 T14438 arg1Of Antibodies,against
R11173 T14437 T14451 arg1Of Antibodies,were
R11174 T14437 T14452 arg2Of Antibodies,purchased
R11175 T14441 T14439 arg1Of BMP-receptors,the
R11176 T14441 T14440 arg1Of BMP-receptors,human
R11177 T14442 T14443 arg1Of Act-RIA,","
R11178 T14443 T14445 arg1Of ",",","
R11179 T14444 T14443 arg2Of BMP-RIB,","
R1118 T1407 T1408 arg1Of BMP-6,","
R11180 T14445 T14447 arg1Of ",",","
R11181 T14446 T14445 arg2Of BMPR-II,","
R11182 T14447 T14449 arg1Of ",",and
R11183 T14448 T14447 arg2Of Act-RIIA,","
R11184 T14449 T14438 arg2Of and,against
R11185 T14449 T14441 arg1Of and,BMP-receptors
R11186 T14450 T14449 arg2Of Act-RIIb,and
R11187 T14452 T14451 arg2Of purchased,were
R11188 T14452 T14453 arg1Of purchased,from
R11189 T14457 T14453 arg2Of Systems,from
R1119 T1407 T1409 arg1Of BMP-6,like
R11190 T14457 T14454 arg1Of Systems,R
R11191 T14457 T14455 arg1Of Systems,&
R11192 T14457 T14456 arg1Of Systems,D
R11193 T14457 T14458 arg1Of Systems,(
R11194 T14459 T14458 arg2Of Abingdon,(
R11195 T14459 T14460 arg1Of Abingdon,","
R11196 T14459 T14461 arg1Of Abingdon,UK
R11197 T14462 T14458 arg3Of ),(
R11198 T14463 T14464 arg1Of Detection,of
R11199 T14463 T14467 arg1Of Detection,has
R112 T234 T241 arg1Of role,has
R1120 T1407 T1414 arg1Of BMP-6,","
R11200 T14463 T14468 arg1Of Detection,been
R11201 T14463 T14469 arg2Of Detection,tried
R11202 T14466 T14464 arg2Of BMP-6-protein,of
R11203 T14466 T14465 arg1Of BMP-6-protein,the
R11204 T14469 T14467 arg2Of tried,has
R11205 T14469 T14468 arg2Of tried,been
R11206 T14469 T14470 arg1Of tried,with
R11207 T14473 T14470 arg2Of antibodies,with
R11208 T14473 T14471 arg1Of antibodies,the
R11209 T14473 T14472 arg1Of antibodies,following
R1121 T1413 T1409 arg2Of members,like
R11210 T14473 T14474 arg1Of antibodies,:
R11211 T14477 T14475 arg1Of anti-BMP-6,goat
R11212 T14477 T14476 arg1Of anti-BMP-6,polyclonal
R11213 T14477 T14478 arg1Of anti-BMP-6,(
R11214 T14477 T14489 arg1Of anti-BMP-6,","
R11215 T14480 T14478 arg2Of Cruz,(
R11216 T14480 T14479 arg1Of Cruz,Santa
R11217 T14480 T14481 arg1Of Cruz,","
R11218 T14480 T14486 arg1Of Cruz,","
R11219 T14480 T14487 arg1Of Cruz,USA
R1122 T1413 T1410 arg1Of members,the
R11220 T14483 T14481 arg2Of Diego,","
R11221 T14483 T14482 arg1Of Diego,San
R11222 T14483 T14484 arg1Of Diego,","
R11223 T14485 T14484 arg2Of CA,","
R11224 T14488 T14478 arg3Of ),(
R11225 T14489 T14474 arg2Of ",",:
R11226 T14489 T14497 arg1Of ",",from
R11227 T14492 T14490 arg1Of anti-BMP-6,monoclonal
R11228 T14492 T14491 arg1Of anti-BMP-6,mouse
R11229 T14492 T14493 arg1Of anti-BMP-6,and
R1123 T1413 T1411 arg1Of members,other
R11230 T14493 T14489 arg2Of and,","
R11231 T14496 T14493 arg2Of anti-BMP-6,and
R11232 T14496 T14494 arg1Of anti-BMP-6,polyclonal
R11233 T14496 T14495 arg1Of anti-BMP-6,goat
R11234 T14501 T14498 arg1Of Systems,R
R11235 T14501 T14499 arg1Of Systems,&
R11236 T14501 T14500 arg1Of Systems,D
R11237 T14501 T14502 arg1Of Systems,(
R11238 T14501 T14508 arg1Of Systems,and
R11239 T14503 T14502 arg2Of Abingdon,(
R1124 T1413 T1412 arg1Of members,BMP
R11240 T14503 T14504 arg1Of Abingdon,","
R11241 T14503 T14505 arg1Of Abingdon,UK
R11242 T14506 T14502 arg3Of ),(
R11243 T14508 T14497 arg2Of and,from
R11244 T14508 T14507 arg1Of and,","
R11245 T14511 T14508 arg2Of anti-BMP-6,and
R11246 T14511 T14509 arg1Of anti-BMP-6,mouse
R11247 T14511 T14510 arg1Of anti-BMP-6,monoclonal
R11248 T14511 T14512 arg1Of anti-BMP-6,(
R11249 T14515 T14512 arg2Of Inc,(
R1125 T1414 T1416 arg1Of ",",through
R11250 T14515 T14513 arg1Of Inc,Chemicon
R11251 T14515 T14514 arg1Of Inc,International
R11252 T14515 T14516 arg1Of Inc,","
R11253 T14515 T14520 arg1Of Inc,","
R11254 T14515 T14521 arg1Of Inc,USA
R11255 T14517 T14518 arg1Of Temecula,","
R11256 T14518 T14516 arg2Of ",",","
R11257 T14519 T14518 arg2Of CA,","
R11258 T14522 T14512 arg3Of ),(
R11259 T14523 T14524 arg1Of Characterisation,of
R1126 T1414 T1424 arg1Of ",",[
R11260 T14523 T14527 arg1Of Characterisation,was
R11261 T14523 T14528 arg2Of Characterisation,done
R11262 T14526 T14524 arg2Of pathways,of
R11263 T14526 T14525 arg1Of pathways,BMP-signalling
R11264 T14528 T14527 arg2Of done,was
R11265 T14528 T14540 arg1Of done,(
R11266 T14530 T14528 arg1Of use,done
R11267 T14530 T14529 arg2Of use,by
R11268 T14530 T14531 arg1Of use,of
R11269 T14532 T14531 arg2Of anti-phospho-Smad1,of
R1127 T1414 T1430 arg1Of ",",and
R11270 T14532 T14533 arg1Of anti-phospho-Smad1,","
R11271 T14532 T14535 arg1Of anti-phospho-Smad1,","
R11272 T14534 T14533 arg2Of -5,","
R11273 T14538 T14536 arg1Of polyclonal,-and
R11274 T14538 T14537 arg1Of polyclonal,8
R11275 T14539 T14535 arg2Of antibody,","
R11276 T14539 T14538 arg1Of antibody,polyclonal
R11277 T14541 T14542 arg1Of Chemicon,","
R11278 T14542 T14544 arg1Of ",",","
R11279 T14543 T14542 arg2Of Temecula,","
R1128 T1415 T1414 arg2Of signals,","
R11280 T14544 T14540 arg2Of ",",(
R11281 T14544 T14546 arg1Of ",",","
R11282 T14544 T14547 arg1Of ",",USA
R11283 T14545 T14544 arg2Of CA,","
R11284 T14548 T14540 arg3Of ),(
R11285 T14550 T14549 arg1Of levels,Expression
R11286 T14550 T14551 arg1Of levels,of
R11287 T14550 T14554 arg1Of levels,were
R11288 T14550 T14555 arg2Of levels,detected
R11289 T14553 T14551 arg2Of proteins,of
R1129 T1417 T1418 arg1Of ligation,and
R11290 T14553 T14552 arg1Of proteins,Id1–3
R11291 T14555 T14554 arg2Of detected,were
R11292 T14555 T14556 arg1Of detected,with
R11293 T14555 T14560 arg1Of detected,and
R11294 T14559 T14556 arg2Of antibody,with
R11295 T14559 T14557 arg1Of antibody,polyclonal
R11296 T14559 T14558 arg1Of antibody,rabbit
R11297 T14561 T14562 arg1Of detection,was
R11298 T14561 T14563 arg2Of detection,blocked
R11299 T14563 T14560 arg2Of blocked,and
R113 T234 T242 arg1Of role,been
R1130 T1418 T1416 arg2Of and,through
R11300 T14563 T14562 arg2Of blocked,was
R11301 T14563 T14564 arg1Of blocked,with
R11302 T14565 T14564 arg2Of blocking,with
R11303 T14566 T14565 arg2Of peptide,blocking
R11304 T14566 T14567 arg1Of peptide,from
R11305 T14570 T14567 arg2Of Biotechnology,from
R11306 T14570 T14568 arg1Of Biotechnology,Santa
R11307 T14570 T14569 arg1Of Biotechnology,Cruz
R11308 T14570 T14571 arg1Of Biotechnology,(
R11309 T14573 T14571 arg2Of Cruz,(
R1131 T1418 T1420 arg1Of and,of
R11310 T14573 T14572 arg1Of Cruz,Santa
R11311 T14573 T14574 arg1Of Cruz,","
R11312 T14573 T14579 arg1Of Cruz,","
R11313 T14576 T14574 arg2Of Diego,","
R11314 T14576 T14575 arg1Of Diego,San
R11315 T14576 T14577 arg1Of Diego,","
R11316 T14578 T14577 arg2Of CA,","
R11317 T14580 T14579 arg2Of USA,","
R11318 T14581 T14571 arg3Of ),(
R11319 T14584 T14582 arg1Of antibodies,As
R1132 T1419 T1418 arg2Of heterodimerzation,and
R11320 T14584 T14583 arg1Of antibodies,secondary
R11321 T14584 T14585 arg1Of antibodies,served
R11322 T14586 T14587 arg1Of anti-mouse,","
R11323 T14587 T14589 arg1Of ",",or
R11324 T14588 T14587 arg2Of anti-goat,","
R11325 T14590 T14589 arg2Of anti-rabbit,or
R11326 T14593 T14585 arg2Of peroxidase,served
R11327 T14593 T14586 arg1Of peroxidase,anti-mouse
R11328 T14593 T14588 arg1Of peroxidase,anti-goat
R11329 T14593 T14590 arg1Of peroxidase,anti-rabbit
R1133 T1422 T1420 arg2Of type,of
R11330 T14593 T14591 arg1Of peroxidase,IgG-
R11331 T14593 T14592 arg1Of peroxidase,horseradish
R11332 T14593 T14594 arg1Of peroxidase,(
R11333 T14593 T14597 arg1Of peroxidase,from
R11334 T14593 T14600 arg1Of peroxidase,(
R11335 T14593 T14605 arg1Of peroxidase,for
R11336 T14595 T14594 arg2Of HRP,(
R11337 T14596 T14594 arg3Of ),(
R11338 T14599 T14597 arg2Of AS,from
R11339 T14599 T14598 arg1Of AS,Dakocytomation
R1134 T1422 T1421 arg1Of type,BMP
R11340 T14601 T14600 arg2Of Copenhagen,(
R11341 T14601 T14602 arg1Of Copenhagen,","
R11342 T14603 T14602 arg2Of Denmark,","
R11343 T14604 T14600 arg3Of ),(
R11344 T14607 T14605 arg2Of analysis,for
R11345 T14607 T14606 arg1Of analysis,immunoblot
R11346 T14608 T14609 arg1Of Anti-β-actin,was
R11347 T14608 T14610 arg1Of Anti-β-actin,from
R11348 T14609 T14626 arg1Of was,anti-CD19-FITC
R11349 T14610 T14609 arg2Of from,was
R1135 T1422 T1423 arg1Of type,I
R11350 T14614 T14610 arg2Of Dickinson,from
R11351 T14614 T14611 arg1Of Dickinson,Santa-Cruz.
R11352 T14614 T14612 arg1Of Dickinson,From
R11353 T14614 T14613 arg1Of Dickinson,Becton
R11354 T14614 T14615 arg1Of Dickinson,(
R11355 T14614 T14623 arg2Of Dickinson,purchased
R11356 T14617 T14615 arg2Of Jose,(
R11357 T14617 T14616 arg1Of Jose,San
R11358 T14617 T14618 arg1Of Jose,","
R11359 T14619 T14618 arg2Of CA,","
R1136 T1425 T1424 arg2Of activin-like-kinase,[
R11360 T14620 T14615 arg3Of ),(
R11361 T14622 T14623 arg1Of we,purchased
R11362 T14623 T14621 arg1Of purchased,","
R11363 T14626 T14624 arg1Of anti-CD19-FITC,anti-CD19-PE
R11364 T14626 T14625 arg1Of anti-CD19-FITC,","
R11365 T14628 T14627 arg1Of antibodies,The
R11366 T14628 T14629 arg2Of antibodies,used
R11367 T14628 T14633 arg1Of antibodies,were
R11368 T14629 T14630 arg1Of used,for
R11369 T14632 T14630 arg2Of sorting,for
R1137 T1425 T1426 arg1Of activin-like-kinase,(
R11370 T14632 T14631 arg1Of sorting,cell
R11371 T14635 T14634 arg1Of PC5,anti-CD19
R11372 T14635 T14636 arg1Of PC5,from
R11373 T14635 T14639 arg1Of PC5,(
R11374 T14635 T14644 arg1Of PC5,and
R11375 T14638 T14636 arg2Of SA,from
R11376 T14638 T14637 arg1Of SA,Immunotech
R11377 T14640 T14639 arg2Of Marseille,(
R11378 T14640 T14641 arg1Of Marseille,","
R11379 T14642 T14641 arg2Of France,","
R1138 T1427 T1426 arg2Of ALK,(
R11380 T14643 T14639 arg3Of ),(
R11381 T14644 T14633 arg2Of and,were
R11382 T14646 T14644 arg2Of PE,and
R11383 T14646 T14645 arg1Of PE,anti-CD27
R11384 T14646 T14647 arg1Of PE,from
R11385 T14649 T14647 arg2Of Dickinson,from
R11386 T14649 T14648 arg1Of Dickinson,Becton
R11387 T14649 T14650 arg1Of Dickinson,","
R11388 T14652 T14650 arg2Of Pharmingen,","
R11389 T14652 T14651 arg1Of Pharmingen,Biosciences
R1139 T1428 T1426 arg3Of ),(
R11390 T14652 T14653 arg1Of Pharmingen,(
R11391 T14655 T14653 arg2Of Diego,(
R11392 T14655 T14654 arg1Of Diego,San
R11393 T14655 T14656 arg1Of Diego,","
R11394 T14657 T14656 arg2Of CA,","
R11395 T14657 T14658 arg1Of CA,","
R11396 T14659 T14658 arg2Of USA,","
R11397 T14660 T14653 arg3Of ),(
R114 T234 T243 arg2Of role,implied
R1140 T1429 T1424 arg3Of ],[
R1141 T1430 T1436 arg1Of and,","
R1142 T1430 T1437 arg1Of and,which
R1143 T1430 T1439 arg1Of and,propagates
R1144 T1435 T1430 arg2Of receptors,and
R1145 T1435 T1431 arg1Of receptors,type
R1146 T1435 T1432 arg1Of receptors,II
R1147 T1435 T1433 arg1Of receptors,serine-threonine
R1148 T1435 T1434 arg1Of receptors,kinase
R1149 T1439 T1438 arg1Of propagates,subsequently
R115 T236 T235 arg2Of BMP-6,of
R1150 T1439 T1442 arg1Of propagates,downstream
R1151 T1439 T1443 arg1Of propagates,by
R1152 T1441 T1439 arg2Of signal,propagates
R1153 T1441 T1440 arg1Of signal,the
R1154 T1444 T1443 arg2Of phosphorylating,by
R1155 T1446 T1444 arg2Of proteins,phosphorylating
R1156 T1446 T1445 arg1Of proteins,Smad
R1157 T1447 T1448 arg1Of BMP-6,can
R1158 T1447 T1449 arg1Of BMP-6,signal
R1159 T1449 T1448 arg2Of signal,can
R116 T240 T237 arg2Of system,in
R1160 T1449 T1450 arg1Of signal,through
R1161 T1452 T1450 arg2Of ligation,through
R1162 T1452 T1451 arg1Of ligation,the
R1163 T1452 T1453 arg1Of ligation,of
R1164 T1452 T1474 arg1Of ligation,","
R1165 T1452 T1475 arg1Of ligation,which
R11658 T15103 T15102 arg1Of sorting,Cell
R11659 T15105 T15104 arg1Of purified,Highly
R1166 T1452 T1476 arg1Of ligation,lead
R11660 T15106 T15107 arg1Of CD19+CD27-,or
R11661 T15108 T15107 arg2Of CD19+CD27+,or
R11662 T15109 T15105 arg1Of cells,purified
R11663 T15109 T15106 arg1Of cells,CD19+CD27-
R11664 T15109 T15108 arg1Of cells,CD19+CD27+
R11665 T15109 T15110 arg1Of cells,were
R11666 T15109 T15111 arg2Of cells,obtained
R11667 T15111 T15110 arg2Of obtained,were
R11668 T15111 T15112 arg1Of obtained,by
R11669 T15111 T15128 arg1Of obtained,","
R1167 T1457 T1455 arg1Of receptors,type
R11670 T15111 T15129 modOf obtained,followed
R11671 T15113 T15112 arg2Of staining,by
R11672 T15113 T15116 arg1Of staining,with
R11673 T15115 T15113 arg2Of cells,staining
R11674 T15115 T15114 arg1Of cells,CD19+
R11675 T15118 T15119 arg1Of PE,and
R11676 T15120 T15119 arg2Of CD19,and
R11677 T15122 T15116 arg2Of mAbs,with
R11678 T15122 T15117 arg1Of mAbs,anti-CD27
R11679 T15122 T15118 arg1Of mAbs,PE
R1168 T1457 T1456 arg1Of receptors,I
R11680 T15122 T15120 arg1Of mAbs,CD19
R11681 T15122 T15121 arg1Of mAbs,PC5
R11682 T15122 T15123 arg1Of mAbs,for
R11683 T15125 T15123 arg2Of minutes,for
R11684 T15125 T15124 arg1Of minutes,30
R11685 T15125 T15126 arg1Of minutes,at
R11686 T15127 T15126 arg2Of 4°C,at
R11687 T15129 T15130 arg1Of followed,by
R11688 T15131 T15132 arg1Of washing,with
R11689 T15131 T15134 arg1Of washing,and
R1169 T1458 T1459 arg1Of Act-RIA,","
R11690 T15133 T15132 arg2Of PBS,with
R11691 T15134 T15130 arg2Of and,by
R11692 T15135 T15134 arg2Of sorting,and
R11693 T15135 T15136 arg1Of sorting,on
R11694 T15138 T15136 arg2Of DiVa,on
R11695 T15138 T15137 arg1Of DiVa,FACS
R11696 T15138 T15139 arg1Of DiVa,from
R11697 T15141 T15139 arg2Of Dickinson,from
R11698 T15141 T15140 arg1Of Dickinson,Becton
R117 T240 T238 arg1Of system,the
R1170 T1459 T1457 arg1Of ",",receptors
R1171 T1459 T1462 arg1Of ",",and
R1172 T1460 T1459 arg2Of BMP-RIA,","
R1173 T1462 T1454 arg1Of and,the
R1174 T1462 T1461 arg1Of and,","
R1175 T1462 T1464 arg1Of and,and
R11752 T15270 T15269 arg1Of analysis,Western-blot
R11753 T15272 T15271 arg1Of cells,B
R11754 T15272 T15273 arg1Of cells,from
R11755 T15272 T15279 arg1Of cells,were
R11756 T15272 T15280 arg2Of cells,lysed
R11757 T15275 T15274 arg1Of blood,peripheral
R11758 T15275 T15276 arg1Of blood,or
R11759 T15276 T15273 arg2Of or,from
R1176 T1463 T1462 arg2Of BMP-RIB,and
R11760 T15278 T15276 arg2Of cell-lines,or
R11761 T15278 T15277 arg2Of cell-lines,cultured
R11762 T15280 T15279 arg2Of lysed,were
R11763 T15280 T15281 arg1Of lysed,in
R11764 T15283 T15281 arg2Of buffer,in
R11765 T15283 T15282 arg1Of buffer,lysis
R11766 T15283 T15284 arg1Of buffer,(
R11767 T15287 T15285 arg1Of %,glycerol
R11768 T15287 T15286 arg1Of %,10
R11769 T15287 T15288 arg1Of %,","
R1177 T1464 T1453 arg2Of and,of
R11770 T15288 T15292 arg1Of ",",","
R11771 T15291 T15288 arg2Of %,","
R11772 T15291 T15289 arg1Of %,β-mercaptoethanol
R11773 T15291 T15290 arg1Of %,5
R11774 T15292 T15300 arg1Of ",",","
R11775 T15293 T15294 arg1Of 0.0625,M
R11776 T15295 T15292 arg2Of Tris-HCL,","
R11777 T15295 T15293 arg1Of Tris-HCL,0.0625
R11778 T15295 T15296 arg1Of Tris-HCL,[
R11779 T15297 T15296 arg2Of pH,[
R1178 T1468 T1466 arg1Of receptors,type
R11780 T15297 T15298 arg1Of pH,6.8
R11781 T15299 T15296 arg3Of ],[
R11782 T15300 T15284 arg2Of ",",(
R11783 T15305 T15304 arg2Of SDS,[
R11784 T15306 T15304 arg3Of ],[
R11785 T15307 T15308 arg1Of 2.5,%
R11786 T15309 T15300 arg2Of w/vol,","
R11787 T15309 T15301 arg1Of w/vol,sodium
R11788 T15309 T15302 arg1Of w/vol,dodecyl
R11789 T15309 T15303 arg1Of w/vol,sulphate
R1179 T1468 T1467 arg1Of receptors,II
R11790 T15309 T15304 arg1Of w/vol,[
R11791 T15309 T15307 arg1Of w/vol,2.5
R11792 T15310 T15284 arg3Of ),(
R11793 T15312 T15311 arg1Of protein,Total
R11794 T15312 T15313 arg1Of protein,(
R11795 T15312 T15317 arg1Of protein,from
R11796 T15312 T15320 arg1Of protein,was
R11797 T15312 T15321 arg2Of protein,run
R11798 T15312 T15334 arg1Of protein,blotted
R11799 T15315 T15313 arg2Of μg,(
R118 T240 T239 arg1Of system,immune
R1180 T1469 T1470 arg1Of BMP-RII,","
R11800 T15315 T15314 arg1Of μg,30–100
R11801 T15316 T15313 arg3Of ),(
R11802 T15319 T15317 arg2Of sample,from
R11803 T15319 T15318 arg1Of sample,each
R11804 T15321 T15320 arg2Of run,was
R11805 T15321 T15322 arg1Of run,on
R11806 T15321 T15333 arg1Of run,and
R11807 T15324 T15323 arg1Of %,10
R11808 T15324 T15325 arg1Of %,or
R11809 T15325 T15327 arg1Of or,%
R1181 T1470 T1472 arg1Of ",",and
R11810 T15326 T15325 arg2Of 12,or
R11811 T15330 T15329 arg2Of SDS/PAGE,(
R11812 T15331 T15329 arg3Of ),(
R11813 T15332 T15322 arg2Of gels,on
R11814 T15332 T15324 arg1Of gels,%
R11815 T15332 T15326 arg1Of gels,12
R11816 T15332 T15328 arg1Of gels,SDS/polyacrylamide
R11817 T15332 T15329 arg1Of gels,(
R11818 T15333 T15338 arg1Of and,(
R11819 T15334 T15333 arg2Of blotted,and
R1182 T1471 T1470 arg2Of Act-RIIA,","
R11820 T15334 T15335 arg1Of blotted,onto
R11821 T15337 T15335 arg2Of filters,onto
R11822 T15337 T15336 arg1Of filters,nitrocellulose
R11823 T15339 T15340 arg1Of Protran,;
R11824 T15340 T15338 arg2Of ;,(
R11825 T15344 T15340 arg2Of GmbH,;
R11826 T15344 T15341 arg1Of GmbH,Schleicher
R11827 T15344 T15342 arg1Of GmbH,&
R11828 T15344 T15343 arg1Of GmbH,Schuell
R11829 T15344 T15345 arg1Of GmbH,","
R1183 T1472 T1464 arg2Of and,and
R11830 T15346 T15345 arg2Of Dassel,","
R11831 T15346 T15347 arg1Of Dassel,","
R11832 T15348 T15347 arg2Of Germany,","
R11833 T15349 T15338 arg3Of ),(
R11834 T15350 T15351 arg1Of Blocking,","
R11835 T15351 T15353 arg1Of ",",and
R11836 T15352 T15351 arg2Of washing,","
R11837 T15353 T15355 arg1Of and,of
R11838 T15353 T15361 arg1Of and,were
R11839 T15353 T15362 arg2Of and,done
R1184 T1472 T1465 arg1Of and,the
R11840 T15354 T15353 arg2Of incubation,and
R11841 T15357 T15355 arg2Of filters,of
R11842 T15357 T15356 arg1Of filters,the
R11843 T15357 T15358 arg1Of filters,with
R11844 T15360 T15358 arg2Of antibodies,with
R11845 T15360 T15359 arg1Of antibodies,primary
R11846 T15362 T15361 arg2Of done,were
R11847 T15362 T15363 arg1Of done,according
R11848 T15362 T15369 arg1Of done,at
R11849 T15364 T15363 arg2Of to,according
R1185 T1472 T1468 arg1Of and,receptors
R11850 T15366 T15365 arg1Of manufacturer,the
R11851 T15366 T15367 arg2Of manufacturer,'s
R11852 T15368 T15364 arg2Of protocols,to
R11853 T15368 T15367 arg1Of protocols,'s
R11854 T15371 T15369 arg2Of temperature,at
R11855 T15371 T15370 arg1Of temperature,room
R11856 T15371 T15372 arg1Of temperature,(
R11857 T15373 T15372 arg2Of RT,(
R11858 T15374 T15372 arg3Of ),(
R11859 T15376 T15375 arg2Of washing,After
R1186 T1473 T1472 arg2Of Act-RIIB,and
R11860 T15376 T15377 arg1Of washing,with
R11861 T15379 T15377 arg2Of %,with
R11862 T15379 T15378 arg1Of %,TBS/0.1
R11863 T15379 T15380 arg1Of %,Tween-20
R11864 T15379 T15381 arg1Of %,(
R11865 T15382 T15381 arg2Of TBS-T,(
R11866 T15383 T15381 arg3Of ),(
R11867 T15386 T15385 arg1Of filters,the
R11868 T15386 T15387 arg1Of filters,were
R11869 T15386 T15388 arg2Of filters,incubated
R1187 T1476 T1477 arg1Of lead,to
R11870 T15388 T15376 arg2Of incubated,washing
R11871 T15388 T15384 arg1Of incubated,","
R11872 T15388 T15387 arg2Of incubated,were
R11873 T15388 T15389 arg1Of incubated,with
R11874 T15391 T15389 arg2Of peroxidase,with
R11875 T15391 T15390 arg1Of peroxidase,horseradish
R11876 T15391 T15392 arg1Of peroxidase,(
R11877 T15391 T15395 arg2Of peroxidase,coupled
R11878 T15393 T15392 arg2Of HRP,(
R11879 T15394 T15392 arg3Of ),(
R1188 T1479 T1477 arg2Of phosphorylation,to
R11880 T15395 T15396 arg1Of coupled,to
R11881 T15399 T15396 arg2Of antibodies,to
R11882 T15399 T15397 arg1Of antibodies,relevant
R11883 T15399 T15398 arg1Of antibodies,secondary
R11884 T15401 T15375 arg1Of see,After
R11885 T15401 T15400 arg1Of see,(
R11886 T15401 T15402 arg1Of see,above
R11887 T15401 T15403 arg1Of see,)
R11888 T15401 T15404 arg1Of see,for
R11889 T15406 T15404 arg2Of minutes,for
R1189 T1479 T1478 arg1Of phosphorylation,the
R11890 T15406 T15405 arg1Of minutes,60
R11891 T15406 T15407 arg1Of minutes,at
R11892 T15408 T15401 arg2Of RT,see
R11893 T15410 T15409 arg1Of activity,Enzyme
R11894 T15410 T15411 arg1Of activity,was
R11895 T15410 T15412 arg2Of activity,visualised
R11896 T15412 T15411 arg2Of visualised,was
R11897 T15412 T15420 arg1Of visualised,(
R11898 T15417 T15412 arg1Of system,visualised
R11899 T15417 T15413 arg2Of system,by
R119 T243 T241 arg2Of implied,has
R1190 T1479 T1480 arg1Of phosphorylation,of
R11900 T15417 T15414 arg1Of system,the
R11901 T15417 T15415 arg2Of system,enhanced
R11902 T15417 T15416 arg1Of system,chemiluminescence
R11903 T15417 T15418 arg1Of system,","
R11904 T15419 T15418 arg2Of ECL+PLUS,","
R11905 T15421 T15422 arg1Of Amersham,","
R11906 T15422 T15420 arg2Of ",",(
R11907 T15422 T15424 arg1Of ",",","
R11908 T15423 T15422 arg2Of Buckinghamshire,","
R11909 T15425 T15424 arg2Of UK,","
R1191 T1483 T1480 arg2Of Smads,of
R11910 T15426 T15420 arg3Of ),(
R11911 T15428 T15427 arg1Of analysis,Densitometric
R11912 T15428 T15429 arg1Of analysis,was
R11913 T15428 T15430 arg2Of analysis,performed
R11914 T15430 T15429 arg2Of performed,was
R11915 T15433 T15430 arg1Of hyperfilms,performed
R11916 T15433 T15431 arg2Of hyperfilms,by
R11917 T15433 T15432 arg1Of hyperfilms,scanning
R11918 T15433 T15434 arg1Of hyperfilms,on
R11919 T15438 T15434 arg2Of SI,on
R1192 T1483 T1481 arg1Of Smads,the
R11920 T15438 T15435 arg1Of SI,a
R11921 T15438 T15436 arg1Of SI,Personal
R11922 T15438 T15437 arg1Of SI,Densitometer
R11923 T15438 T15439 arg1Of SI,(
R11924 T15441 T15439 arg2Of Dynamics,(
R11925 T15441 T15440 arg1Of Dynamics,Molecular
R11926 T15441 T15442 arg1Of Dynamics,","
R11927 T15443 T15442 arg2Of Sunnyvale,","
R11928 T15443 T15444 arg1Of Sunnyvale,","
R11929 T15445 T15444 arg2Of CA,","
R1193 T1483 T1482 arg1Of Smads,receptor
R11930 T15446 T15439 arg3Of ),(
R11931 T15447 T15448 arg1Of Quantification,of
R11932 T15447 T15455 arg1Of Quantification,was
R11933 T15447 T15456 arg2Of Quantification,calculated
R11934 T15449 T15450 arg1Of Id1,","
R11935 T15450 T15452 arg1Of ",",and
R11936 T15451 T15450 arg2Of Id2,","
R11937 T15453 T15452 arg2Of Id3,and
R11938 T15454 T15448 arg2Of protein,of
R11939 T15454 T15449 arg1Of protein,Id1
R1194 T1483 T1484 arg1Of Smads,(
R11940 T15454 T15451 arg1Of protein,Id2
R11941 T15454 T15453 arg1Of protein,Id3
R11942 T15456 T15455 arg2Of calculated,was
R11943 T15456 T15457 arg1Of calculated,by
R11944 T15458 T15457 arg2Of normalizing,by
R11945 T15462 T15458 arg2Of bands,normalizing
R11946 T15462 T15459 arg1Of bands,the
R11947 T15462 T15460 arg1Of bands,specific
R11948 T15462 T15461 arg1Of bands,protein
R11949 T15462 T15463 arg1Of bands,to
R1195 T1485 T1486 arg1Of Smad-1,","
R11950 T15462 T15465 arg1Of bands,using
R11951 T15464 T15463 arg2Of β-actin,to
R11952 T15469 T15465 arg2Of software,using
R11953 T15469 T15466 arg1Of software,Image
R11954 T15469 T15467 arg1Of software,Quant
R11955 T15469 T15468 arg1Of software,5.5
R11956 T15469 T15470 arg1Of software,(
R11957 T15472 T15470 arg2Of Dynamics,(
R11958 T15472 T15471 arg1Of Dynamics,Molecular
R11959 T15473 T15470 arg3Of ),(
R1196 T1486 T1489 arg1Of ",",and
R1197 T1487 T1486 arg2Of Smad-5,","
R1198 T1489 T1484 arg2Of and,(
R1199 T1489 T1488 arg1Of and,","
R11992 T15608 T15609 arg1Of Analysis,of
R11993 T15612 T15609 arg2Of RNA,of
R11994 T15612 T15610 arg1Of RNA,BMP-6
R11995 T15612 T15611 arg1Of RNA,messenger
R11996 T15612 T15613 arg1Of RNA,(
R11997 T15614 T15613 arg2Of mRNA,(
R11998 T15615 T15613 arg3Of ),(
R11999 T15616 T15608 arg1Of expression,Analysis
R120 T243 T242 arg2Of implied,been
R1200 T1490 T1489 arg2Of Smad-8,and
R12000 T15618 T15617 arg1Of expression,Endogenous
R12001 T15618 T15619 arg1Of expression,of
R12002 T15618 T15623 arg1Of expression,was
R12003 T15618 T15624 arg2Of expression,examined
R12004 T15622 T15619 arg2Of gene,of
R12005 T15622 T15620 arg1Of gene,the
R12006 T15622 T15621 arg1Of gene,BMP-6
R12007 T15624 T15623 arg2Of examined,was
R12008 T15629 T15624 arg1Of reaction,examined
R12009 T15629 T15625 arg2Of reaction,by
R1201 T1491 T1484 arg3Of ),(
R12010 T15629 T15626 arg1Of reaction,reverse
R12011 T15629 T15627 arg1Of reaction,transcription-polymerase
R12012 T15629 T15628 arg1Of reaction,chain
R12013 T15631 T15630 arg1Of RNA,Total
R12014 T15631 T15632 arg1Of RNA,was
R12015 T15631 T15633 arg2Of RNA,isolated
R12016 T15633 T15632 arg2Of isolated,was
R12017 T15634 T15633 arg3Of using,isolated
R12018 T15634 T15635 arg1Of using,Absolutely
R12019 T15634 T15648 arg1Of using,according
R1202 T1494 T1492 arg1Of Smads,The
R12020 T15638 T15636 arg1Of Miniprep,RNA™
R12021 T15638 T15637 arg1Of Miniprep,RT-PCR
R12022 T15639 T15634 arg2Of Kit,using
R12023 T15639 T15638 arg1Of Kit,Miniprep
R12024 T15639 T15640 arg1Of Kit,(
R12025 T15642 T15641 arg1Of Europe,Stratagene
R12026 T15642 T15643 arg1Of Europe,","
R12027 T15643 T15640 arg2Of ",",(
R12028 T15643 T15645 arg1Of ",",","
R12029 T15643 T15646 arg1Of ",",Netherland
R1203 T1494 T1493 arg1Of Smads,R-
R12030 T15644 T15643 arg2Of Amsterdam,","
R12031 T15647 T15640 arg3Of ),(
R12032 T15649 T15648 arg2Of to,according
R12033 T15652 T15649 arg2Of instructions,to
R12034 T15652 T15650 arg1Of instructions,the
R12035 T15652 T15651 arg1Of instructions,manufacturers
R12036 T15653 T15654 arg1Of Quantification,of
R12037 T15653 T15659 arg1Of Quantification,was
R12038 T15653 T15660 arg2Of Quantification,achieved
R12039 T15658 T15654 arg2Of RNA,of
R1204 T1494 T1496 arg1Of Smads,form
R12040 T15658 T15655 arg1Of RNA,the
R12041 T15658 T15656 arg2Of RNA,isolated
R12042 T15658 T15657 arg1Of RNA,total
R12043 T15660 T15659 arg2Of achieved,was
R12044 T15660 T15661 arg1Of achieved,by
R12045 T15662 T15661 arg2Of using,by
R12046 T15665 T15662 arg2Of measurements,using
R12047 T15665 T15663 arg1Of measurements,spectrophotometric
R12048 T15665 T15664 arg1Of measurements,OD260
R12049 T15667 T15666 arg1Of amounts,Equal
R1205 T1494 T1505 arg1Of Smads,are
R12050 T15667 T15668 arg1Of amounts,of
R12051 T15667 T15670 arg1Of amounts,were
R12052 T15669 T15668 arg2Of RNA,of
R12053 T15670 T15671 arg1Of were,then
R12054 T15672 T15670 arg2Of reverse,were
R12055 T15672 T15673 modOf reverse,transcribed
R12056 T15673 T15674 arg1Of transcribed,to
R12057 T15675 T15674 arg2Of cDNA,to
R12058 T15675 T15676 arg1Of cDNA,with
R12059 T15678 T15677 arg1Of Reverse,TaqMan®
R1206 T1494 T1506 arg2Of Smads,translocated
R12060 T15680 T15676 arg2Of Reagents,with
R12061 T15680 T15678 arg1Of Reagents,Reverse
R12062 T15680 T15679 arg1Of Reagents,Transcription
R12063 T15680 T15681 arg1Of Reagents,(
R12064 T15683 T15682 arg1Of Biosystems,Applied
R12065 T15683 T15684 arg1Of Biosystems,","
R12066 T15684 T15687 arg1Of ",",","
R12067 T15686 T15684 arg2Of City,","
R12068 T15686 T15685 arg1Of City,Foster
R12069 T15687 T15681 arg2Of ",",(
R1207 T1496 T1498 arg1Of form,with
R12070 T15687 T15689 arg1Of ",",","
R12071 T15688 T15687 arg2Of CA,","
R12072 T15690 T15689 arg2Of U.S.A,","
R12073 T15691 T15681 arg3Of ),(
R12074 T15693 T15692 arg1Of measure,To
R12075 T15695 T15693 arg2Of expression,measure
R12076 T15695 T15694 arg1Of expression,mRNA
R12077 T15695 T15696 arg1Of expression,of
R12078 T15697 T15696 arg2Of BMP6,of
R12079 T15699 T15700 arg1Of Id1–Id4,and
R1208 T1496 T1504 arg1Of form,and
R12080 T15701 T15700 arg2Of PGK1,and
R12081 T15702 T15693 arg1Of PCR,measure
R12082 T15702 T15699 arg1Of PCR,Id1–Id4
R12083 T15702 T15701 arg1Of PCR,PGK1
R12084 T15702 T15703 arg1Of PCR,were
R12085 T15702 T15704 arg2Of PCR,carried
R12086 T15704 T15692 modOf carried,To
R12087 T15704 T15698 arg1Of carried,","
R12088 T15704 T15703 arg2Of carried,were
R12089 T15704 T15705 arg1Of carried,out
R1209 T1497 T1496 arg2Of complexes,form
R12090 T15704 T15706 arg1Of carried,with
R12091 T15710 T15706 arg2Of mix,with
R12092 T15710 T15707 arg1Of mix,TaqMan®
R12093 T15710 T15708 arg1Of mix,universal
R12094 T15710 T15709 arg1Of mix,master
R12095 T15711 T15712 arg1Of Primers,and
R12096 T15712 T15714 arg1Of and,were
R12097 T15712 T15715 arg2Of and,provided
R12098 T15713 T15712 arg2Of probes,and
R12099 T15715 T15714 arg2Of provided,were
R121 T246 T243 arg1Of studies,implied
R1210 T1500 T1498 arg2Of co-Smad,with
R12100 T15717 T15715 arg1Of Assay-on-Demand,provided
R12101 T15717 T15716 arg2Of Assay-on-Demand,by
R12102 T15717 T15718 arg1Of Assay-on-Demand,(
R12103 T15720 T15718 arg2Of Biosystems,(
R12104 T15720 T15719 arg1Of Biosystems,Applied
R12105 T15721 T15718 arg3Of ),(
R12106 T15723 T15722 arg1Of reactions,PCR
R12107 T15723 T15724 arg1Of reactions,were
R12108 T15723 T15725 arg2Of reactions,carried
R12109 T15725 T15724 arg2Of carried,were
R1211 T1500 T1499 arg1Of co-Smad,the
R12110 T15725 T15726 arg1Of carried,out
R12111 T15725 T15727 arg1Of carried,in
R12112 T15730 T15727 arg2Of volume,in
R12113 T15730 T15728 arg1Of volume,a
R12114 T15730 T15729 arg1Of volume,final
R12115 T15730 T15731 arg1Of volume,of
R12116 T15733 T15732 arg1Of μl,25
R12117 T15733 T15734 arg1Of μl,(
R12118 T15733 T15737 arg1Of μl,or
R12119 T15735 T15734 arg2Of BMP-6,(
R1212 T1500 T1501 arg1Of co-Smad,(
R12120 T15736 T15734 arg3Of ),(
R12121 T15737 T15731 arg2Of or,of
R12122 T15739 T15737 arg2Of μl,or
R12123 T15739 T15738 arg1Of μl,20
R12124 T15739 T15740 arg1Of μl,(
R12125 T15741 T15740 arg2Of ID1,(
R12126 T15742 T15740 arg3Of ),(
R12127 T15744 T15743 arg1Of cDNA,The
R12128 T15744 T15745 arg2Of cDNA,added
R12129 T15744 T15749 arg1Of cDNA,was
R1213 T1502 T1501 arg2Of Smad4,(
R12130 T15744 T15750 arg1Of cDNA,equivalent
R12131 T15745 T15746 arg1Of added,to
R12132 T15748 T15746 arg2Of reaction,to
R12133 T15748 T15747 arg1Of reaction,each
R12134 T15750 T15749 arg2Of equivalent,was
R12135 T15750 T15751 arg1Of equivalent,to
R12136 T15753 T15751 arg2Of input,to
R12137 T15753 T15752 arg1Of input,the
R12138 T15753 T15754 arg1Of input,of
R12139 T15756 T15754 arg2Of ng,of
R1214 T1503 T1501 arg3Of ),(
R12140 T15756 T15755 arg1Of ng,20
R12141 T15756 T15757 arg1Of ng,of
R12142 T15759 T15757 arg2Of RNA,of
R12143 T15759 T15758 arg1Of RNA,total
R12144 T15762 T15760 arg1Of expression,The
R12145 T15762 T15761 arg1Of expression,gene
R12146 T15762 T15763 arg1Of expression,was
R12147 T15762 T15764 arg2Of expression,quantified
R12148 T15762 T15765 arg1Of expression,using
R12149 T15764 T15763 arg2Of quantified,was
R1215 T1504 T1495 arg1Of and,then
R12150 T15765 T15764 arg3Of using,quantified
R12151 T15765 T15782 arg1Of using,as
R12152 T15769 T15766 arg1Of method,the
R12153 T15769 T15767 arg1Of method,standard
R12154 T15769 T15768 arg1Of method,curve
R12155 T15769 T15770 arg1Of method,(
R12156 T15769 T15774 arg1Of method,or
R12157 T15771 T15770 arg2Of BMP6,(
R12158 T15772 T15770 arg3Of ),(
R12159 T15774 T15765 arg2Of or,using
R1216 T1506 T1504 arg2Of translocated,and
R12160 T15774 T15773 arg1Of or,","
R12161 T15778 T15774 arg2Of method,or
R12162 T15778 T15775 arg1Of method,the
R12163 T15778 T15776 arg1Of method,comparative
R12164 T15778 T15777 arg1Of method,CT
R12165 T15778 T15779 arg1Of method,(
R12166 T15780 T15779 arg2Of Id1,(
R12167 T15781 T15779 arg3Of ),(
R12168 T15783 T15782 arg2Of described,as
R12169 T15783 T15784 arg1Of described,in
R1217 T1506 T1505 arg2Of translocated,are
R12170 T15787 T15784 arg2Of Bulletin,in
R12171 T15787 T15785 arg1Of Bulletin,ABI7700
R12172 T15787 T15786 arg1Of Bulletin,User
R12173 T15787 T15788 arg1Of Bulletin,2
R12174 T15787 T15789 arg1Of Bulletin,(
R12175 T15791 T15789 arg2Of Biosystems,(
R12176 T15791 T15790 arg1Of Biosystems,Applied
R12177 T15792 T15789 arg3Of ),(
R12178 T15794 T15793 arg1Of expression,The
R12179 T15794 T15795 arg1Of expression,was
R1218 T1506 T1507 arg1Of translocated,into
R12180 T15794 T15797 arg2Of expression,normalized
R12181 T15797 T15795 arg2Of normalized,was
R12182 T15797 T15796 arg1Of normalized,then
R12183 T15797 T15798 arg1Of normalized,to
R12184 T15801 T15798 arg2Of level,to
R12185 T15801 T15799 arg1Of level,the
R12186 T15801 T15800 arg1Of level,expression
R12187 T15801 T15802 arg1Of level,of
R12188 T15803 T15802 arg2Of PGK1,of
R12189 T15804 T15805 arg1Of PGK1,was
R1219 T1509 T1507 arg2Of nucleus,into
R12190 T15804 T15806 arg2Of PGK1,chosen
R12191 T15806 T15805 arg2Of chosen,was
R12192 T15806 T15807 arg1Of chosen,","
R12193 T15806 T15808 arg1Of chosen,because
R12194 T15809 T15810 arg1Of it,has
R12195 T15809 T15811 arg1Of it,been
R12196 T15809 T15812 arg2Of it,shown
R12197 T15809 T15814 arg1Of it,have
R12198 T15812 T15808 arg2Of shown,because
R12199 T15812 T15810 arg2Of shown,has
R122 T246 T244 arg2Of studies,by
R1220 T1509 T1508 arg1Of nucleus,the
R12200 T15812 T15811 arg2Of shown,been
R12201 T15812 T15821 arg1Of shown,[
R12202 T15814 T15812 arg3Of have,shown
R12203 T15814 T15813 arg1Of have,to
R12204 T15817 T15814 arg2Of variability,have
R12205 T15817 T15815 arg1Of variability,low
R12206 T15817 T15816 arg1Of variability,expression
R12207 T15817 T15818 arg1Of variability,among
R12208 T15820 T15818 arg2Of specimens,among
R12209 T15820 T15819 arg1Of specimens,lymphocyte
R1221 T1509 T1510 arg1Of nucleus,where
R12210 T15822 T15821 arg2Of 56,[
R12211 T15823 T15821 arg3Of ],[
R12212 T15825 T15824 arg1Of levels,Expression
R12213 T15825 T15826 arg1Of levels,in
R12214 T15825 T15829 arg1Of levels,were
R12215 T15825 T15831 arg2Of levels,related
R12216 T15828 T15826 arg2Of cells,in
R12217 T15828 T15827 arg1Of cells,B
R12218 T15831 T15829 arg2Of related,were
R12219 T15831 T15830 arg1Of related,then
R1222 T1511 T1512 arg1Of they,exert
R12220 T15831 T15832 arg1Of related,to
R12221 T15835 T15832 arg2Of levels,to
R12222 T15835 T15833 arg1Of levels,the
R12223 T15835 T15834 arg1Of levels,expression
R12224 T15835 T15836 arg1Of levels,in
R12225 T15838 T15836 arg2Of cells,in
R12226 T15838 T15837 arg1Of cells,Ramos
R1223 T1512 T1510 arg2Of exert,where
R1224 T1512 T1515 arg1Of exert,[
R1225 T1514 T1512 arg2Of regulation,exert
R1226 T1514 T1513 arg1Of regulation,gene
R1227 T1516 T1515 arg2Of "1,13",[
R1228 T1517 T1515 arg3Of ],[
R1229 T1521 T1518 arg2Of role,Given
R123 T246 T245 arg1Of studies,various
R1230 T1521 T1519 arg1Of role,the
R1231 T1521 T1520 arg2Of role,reported
R1232 T1521 T1522 arg1Of role,of
R1233 T1521 T1524 arg1Of role,in
R1234 T1523 T1522 arg2Of BMP-6,of
R1235 T1526 T1525 arg1Of malignancies,B-cell
R1236 T1526 T1527 arg1Of malignancies,and
R1237 T1527 T1524 arg2Of and,in
R1238 T1530 T1527 arg2Of cells,and
R1239 T1530 T1528 arg1Of cells,haematopoietic
R124 T246 T247 arg1Of studies,of
R1240 T1530 T1529 arg1Of cells,progenitor
R1241 T1532 T1533 arg1Of we,wanted
R1242 T1532 T1535 arg1Of we,explore
R1243 T1533 T1518 arg1Of wanted,Given
R1244 T1533 T1531 arg1Of wanted,","
R1245 T1535 T1533 arg2Of explore,wanted
R1246 T1535 T1534 arg1Of explore,to
R1247 T1535 T1539 arg1Of explore,in
R1248 T1538 T1535 arg2Of role,explore
R1249 T1538 T1536 arg1Of role,its
R125 T248 T249 arg1Of malignant,and
R1250 T1538 T1537 arg1Of role,potential
R1251 T1543 T1539 arg2Of cells,in
R1252 T1543 T1540 arg1Of cells,normal
R12526 T16238 T16237 arg1Of proliferation,Cell
R12527 T16240 T16241 arg1Of estimation,of
R12528 T16240 T16239 arg2Of estimation,For
R12529 T16243 T16241 arg2Of synthesis,of
R1253 T1543 T1541 arg1Of cells,human
R12530 T16243 T16242 arg1Of synthesis,DNA
R12531 T16246 T16245 arg1Of cells,CD19+
R12532 T16246 T16247 arg1Of cells,(
R12533 T16246 T16254 arg1Of cells,or
R12534 T16248 T16249 arg1Of 7.5,×
R12535 T16250 T16249 arg2Of 104,×
R12536 T16252 T16247 arg2Of ml,(
R12537 T16252 T16248 arg1Of ml,7.5
R12538 T16252 T16250 arg1Of ml,104
R12539 T16252 T16251 arg1Of ml,cells/0.2
R1254 T1543 T1542 arg1Of cells,B
R12540 T16253 T16247 arg3Of ),(
R12541 T16254 T16264 arg1Of or,were
R12542 T16254 T16265 arg2Of or,cultured
R12543 T16256 T16254 arg2Of cells,or
R12544 T16256 T16255 arg1Of cells,Ramos
R12545 T16256 T16257 arg1Of cells,(
R12546 T16262 T16257 arg2Of ml,(
R12547 T16262 T16258 arg1Of ml,1
R12548 T16262 T16259 arg1Of ml,×
R12549 T16262 T16260 arg1Of ml,104
R1255 T1544 T1545 arg1Of We,studied
R12550 T16262 T16261 arg1Of ml,cells/0.2
R12551 T16263 T16257 arg3Of ),(
R12552 T16265 T16244 arg1Of cultured,","
R12553 T16265 T16239 arg1Of cultured,For
R12554 T16265 T16264 arg2Of cultured,were
R12555 T16265 T16266 arg1Of cultured,in
R12556 T16267 T16266 arg2Of triplicate,in
R12557 T16267 T16268 arg1Of triplicate,in
R12558 T16270 T16268 arg2Of wells,in
R12559 T16270 T16269 arg1Of wells,microtiter
R1256 T1547 T1545 arg2Of effects,studied
R12560 T16272 T16271 arg1Of cells,The
R12561 T16272 T16273 arg1Of cells,were
R12562 T16272 T16274 arg2Of cells,pulsed
R12563 T16274 T16273 arg2Of pulsed,were
R12564 T16274 T16275 arg1Of pulsed,with
R12565 T16276 T16277 arg1Of 3.7,×
R12566 T16277 T16275 arg2Of ×,with
R12567 T16280 T16279 arg2Of 3H,[
R12568 T16281 T16279 arg3Of ],[
R12569 T16282 T16277 arg2Of thymidine,×
R1257 T1547 T1546 arg1Of effects,the
R12570 T16282 T16278 arg1Of thymidine,104Bq
R12571 T16282 T16279 arg1Of thymidine,[
R12572 T16282 T16283 arg1Of thymidine,(
R12573 T16282 T16290 arg1Of thymidine,for
R12574 T16284 T16285 arg1Of Amersham,","
R12575 T16285 T16283 arg2Of ",",(
R12576 T16285 T16287 arg1Of ",",","
R12577 T16286 T16285 arg2Of Buckinghamshire,","
R12578 T16288 T16287 arg2Of UK,","
R12579 T16289 T16283 arg3Of ),(
R1258 T1547 T1548 arg1Of effects,of
R12580 T16294 T16290 arg2Of h,for
R12581 T16294 T16291 arg1Of h,the
R12582 T16294 T16292 arg1Of h,last
R12583 T16294 T16293 arg1Of h,16
R12584 T16294 T16295 arg1Of h,of
R12585 T16298 T16295 arg2Of incubation,of
R12586 T16298 T16296 arg1Of incubation,a
R12587 T16298 T16297 arg1Of incubation,72-h
R12588 T16300 T16299 arg1Of cells,The
R12589 T16300 T16301 arg1Of cells,were
R1259 T1547 T1550 arg1Of effects,on
R12590 T16300 T16302 arg2Of cells,harvested
R12591 T16302 T16301 arg2Of harvested,were
R12592 T16302 T16319 arg1Of harvested,and
R12593 T16303 T16302 arg3Of using,harvested
R12594 T16303 T16308 arg1Of using,(
R12595 T16307 T16303 arg2Of harvester,using
R12596 T16307 T16304 arg1Of harvester,an
R12597 T16307 T16305 arg2Of harvester,automated
R12598 T16307 T16306 arg1Of harvester,cell
R12599 T16311 T16308 arg2Of Company,(
R126 T250 T249 arg2Of rheumatoid,and
R1260 T1549 T1548 arg2Of BMP-6,of
R12600 T16311 T16309 arg1Of Company,Packard
R12601 T16311 T16310 arg1Of Company,Instrument
R12602 T16311 T16312 arg1Of Company,","
R12603 T16311 T16316 arg1Of Company,","
R12604 T16311 T16317 arg1Of Company,USA
R12605 T16313 T16314 arg1Of Meriden,","
R12606 T16314 T16312 arg2Of ",",","
R12607 T16315 T16314 arg2Of CT,","
R12608 T16318 T16308 arg3Of ),(
R12609 T16321 T16320 arg2Of 3H,[
R1261 T1551 T1552 arg1Of proliferation,and
R12610 T16322 T16320 arg3Of ],[
R12611 T16324 T16320 arg1Of incorporation,[
R12612 T16324 T16323 arg1Of incorporation,thymidine
R12613 T16324 T16325 arg1Of incorporation,was
R12614 T16324 T16326 arg2Of incorporation,determined
R12615 T16326 T16319 arg2Of determined,and
R12616 T16326 T16325 arg2Of determined,was
R12617 T16326 T16327 arg1Of determined,in
R12618 T16326 T16331 arg1Of determined,(
R12619 T16330 T16327 arg2Of counter,in
R1262 T1552 T1550 arg2Of and,on
R12620 T16330 T16328 arg1Of counter,a
R12621 T16330 T16329 arg1Of counter,scintillation
R12622 T16332 T16333 arg1Of TopCount,","
R12623 T16333 T16338 arg1Of ",",","
R12624 T16337 T16333 arg2Of Inc.,","
R12625 T16337 T16334 arg1Of Inc.,Packard
R12626 T16337 T16335 arg1Of Inc.,Instrument
R12627 T16337 T16336 arg1Of Inc.,Company
R12628 T16338 T16331 arg2Of ",",(
R12629 T16338 T16340 arg1Of ",",","
R1263 T1552 T1554 arg1Of and,on
R12630 T16339 T16338 arg2Of Meriden,","
R12631 T16341 T16340 arg2Of CT,","
R12632 T16342 T16331 arg3Of ),(
R1264 T1553 T1552 arg2Of apoptosis,and
R1265 T1559 T1554 arg2Of cells,on
R1266 T1559 T1555 arg1Of cells,resting
R1267 T1559 T1556 arg1Of cells,and
R1268 T1559 T1557 arg2Of cells,stimulated
R1269 T1559 T1558 arg1Of cells,B
R127 T251 T247 arg2Of diseases,of
R1270 T1563 T1562 arg1Of expression,the
R1271 T1563 T1564 arg1Of expression,of
R1272 T1563 T1569 arg1Of expression,induced
R1273 T1563 T1585 arg1Of expression,were
R1274 T1563 T1586 arg2Of expression,resolved
R12745 T16481 T16482 arg1Of Determination,of
R12746 T16484 T16482 arg2Of death,of
R12747 T16484 T16483 arg1Of death,cell
R12748 T16486 T16485 arg1Of death,Cell
R12749 T16486 T16487 arg1Of death,was
R1275 T1566 T1565 arg1Of receptors,BMP
R12750 T16486 T16488 arg2Of death,measured
R12751 T16486 T16495 arg1Of death,staining
R12752 T16488 T16487 arg2Of measured,was
R12753 T16488 T16494 arg1Of measured,by
R12754 T16488 T16518 arg1Of measured,for
R12755 T16493 T16488 arg1Of test,measured
R12756 T16493 T16489 arg2Of test,by
R12757 T16493 T16490 arg1Of test,vital
R12758 T16493 T16491 arg1Of test,dye
R12759 T16493 T16492 arg1Of test,exclusion
R1276 T1566 T1567 arg1Of receptors,and
R12760 T16495 T16494 arg2Of staining,by
R12761 T16495 T16497 arg1Of staining,with
R12762 T16496 T16495 arg2Of cells,staining
R12763 T16501 T16497 arg2Of iodide,with
R12764 T16501 T16498 arg1Of iodide,5
R12765 T16501 T16499 arg1Of iodide,μg/ml
R12766 T16501 T16500 arg1Of iodide,propidium
R12767 T16501 T16502 arg1Of iodide,(
R12768 T16504 T16503 arg2Of PI,[
R12769 T16504 T16506 arg1Of PI,;
R1277 T1567 T1564 arg2Of and,of
R12770 T16505 T16503 arg3Of ],[
R12771 T16506 T16509 arg1Of ;,;
R12772 T16508 T16506 arg2Of Corp.,;
R12773 T16508 T16507 arg1Of Corp.,Calbiochem
R12774 T16509 T16514 arg1Of ;,;
R12775 T16511 T16509 arg2Of Jolla,;
R12776 T16511 T16510 arg1Of Jolla,La
R12777 T16511 T16512 arg1Of Jolla,","
R12778 T16513 T16512 arg2Of CA,","
R12779 T16514 T16502 arg2Of ;,(
R1278 T1568 T1567 arg2Of BMP-6,and
R12780 T16516 T16514 arg2Of mg/ml,;
R12781 T16516 T16515 arg1Of mg/ml,5
R12782 T16517 T16502 arg3Of ),(
R12783 T16520 T16518 arg2Of minute,for
R12784 T16520 T16519 arg1Of minute,one
R12785 T16520 T16521 arg1Of minute,on
R12786 T16522 T16521 arg2Of ice,on
R12787 T16525 T16523 arg1Of "1,000",At
R12788 T16525 T16524 arg1Of "1,000",least
R12789 T16526 T16525 arg1Of cells,"1,000"
R1279 T1569 T1576 arg1Of induced,with
R12790 T16526 T16527 arg1Of cells,per
R12791 T16526 T16529 arg1Of cells,were
R12792 T16526 T16530 arg2Of cells,run
R12793 T16528 T16527 arg2Of sample,per
R12794 T16530 T16529 arg2Of run,were
R12795 T16530 T16531 arg1Of run,on
R12796 T16536 T16531 arg2Of cytometer,on
R12797 T16536 T16532 arg1Of cytometer,a
R12798 T16536 T16533 arg1Of cytometer,BD
R12799 T16536 T16534 arg1Of cytometer,FACSCalibur
R128 T251 T248 arg1Of diseases,malignant
R1280 T1569 T1584 arg1Of induced,","
R12800 T16536 T16535 arg1Of cytometer,flow
R1281 T1570 T1569 arg2Of activation,induced
R1282 T1570 T1571 arg1Of activation,of
R1283 T1575 T1571 arg2Of pathway,of
R1284 T1575 T1572 arg1Of pathway,the
R1285 T1575 T1573 arg1Of pathway,Smad
R1286 T1575 T1574 arg1Of pathway,signalling
R12861 T16610 T16609 arg1Of analysis,Statistical
R12862 T16613 T16611 arg1Of significance,The
R12863 T16613 T16612 arg1Of significance,statistical
R12864 T16613 T16614 arg1Of significance,of
R12865 T16613 T16616 arg1Of significance,between
R12866 T16613 T16618 arg1Of significance,was
R12867 T16613 T16619 arg2Of significance,determined
R12868 T16613 T16629 arg1Of significance,applying
R12869 T16615 T16614 arg2Of differences,of
R1287 T1578 T1576 arg2Of regulation,with
R12870 T16617 T16616 arg2Of groups,between
R12871 T16619 T16618 arg2Of determined,was
R12872 T16619 T16627 arg1Of determined,","
R12873 T16619 T16628 arg1Of determined,by
R12874 T16620 T16619 arg3Of using,determined
R12875 T16626 T16620 arg2Of test,using
R12876 T16626 T16621 arg1Of test,the
R12877 T16626 T16622 arg1Of test,paired
R12878 T16626 T16623 arg1Of test,two-tailed
R12879 T16626 T16624 arg1Of test,Wilcoxon
R1288 T1578 T1577 arg1Of regulation,subsequent
R12880 T16626 T16625 arg1Of test,nonparametric
R12881 T16629 T16628 arg2Of applying,by
R12882 T16631 T16629 arg2Of software,applying
R12883 T16631 T16630 arg1Of software,SPSS10.1
R12884 T16631 T16632 arg1Of software,(
R12885 T16634 T16632 arg2Of Inc.,(
R12886 T16634 T16633 arg1Of Inc.,SPSS
R12887 T16634 T16635 arg1Of Inc.,","
R12888 T16634 T16639 arg1Of Inc.,","
R12889 T16634 T16640 arg1Of Inc.,USA
R1289 T1578 T1579 arg1Of regulation,of
R12890 T16636 T16637 arg1Of Chicago,","
R12891 T16637 T16635 arg2Of ",",","
R12892 T16638 T16637 arg2Of IL,","
R12893 T16641 T16632 arg3Of ),(
R12894 T16643 T16642 arg1Of values,P
R12895 T16643 T16644 arg1Of values,less
R12896 T16643 T16647 arg1Of values,were
R12897 T16643 T16648 arg2Of values,considered
R12898 T16643 T16649 arg1Of values,significant
R12899 T16644 T16645 arg1Of less,than
R129 T251 T250 arg1Of diseases,rheumatoid
R1290 T1583 T1579 arg2Of Id1–Id4,of
R12900 T16646 T16645 arg2Of 0.05,than
R12901 T16648 T16647 arg2Of considered,were
R12902 T16649 T16648 arg3Of significant,considered
R1291 T1583 T1580 arg1Of Id1–Id4,the
R1292 T1583 T1581 arg1Of Id1–Id4,target
R1293 T1583 T1582 arg1Of Id1–Id4,genes
R1294 T1584 T1560 arg1Of ",",Furthermore
R1295 T1584 T1561 arg1Of ",",","
R1296 T1586 T1584 arg2Of resolved,","
R1297 T1586 T1585 arg2Of resolved,were
R1298 T1589 T1590 arg1Of we,investigated
R1299 T1590 T1587 arg1Of investigated,Finally
R130 T255 T252 arg2Of study,In
R1300 T1590 T1588 arg1Of investigated,","
R1301 T1593 T1592 arg1Of cells,B
R1302 T1593 T1595 arg1Of cells,were
R1303 T1593 T1596 arg1Of cells,capable
R1304 T1593 T1598 arg1Of cells,producing
R1305 T1595 T1590 arg2Of were,investigated
R1306 T1595 T1591 arg1Of were,whether
R1307 T1595 T1594 arg1Of were,also
R1308 T1596 T1595 arg2Of capable,were
R1309 T1596 T1597 arg1Of capable,of
R131 T255 T253 arg1Of study,the
R1310 T1598 T1597 arg2Of producing,of
R1311 T1599 T1598 arg2Of BMP-6,producing
R132 T255 T254 arg1Of study,present
R133 T257 T258 arg1Of we,explored
R134 T258 T252 arg1Of explored,In
R135 T258 T256 arg1Of explored,","
R136 T260 T258 arg2Of role,explored
R137 T260 T259 arg1Of role,the
R138 T260 T261 arg1Of role,of
R139 T260 T263 arg1Of role,in
R140 T262 T261 arg2Of BMP-6,of
R141 T269 T263 arg2Of cells,in
R142 T269 T264 arg1Of cells,normal
R143 T269 T265 arg1Of cells,human
R144 T269 T266 arg1Of cells,peripheral
R145 T269 T267 arg1Of cells,blood
R146 T269 T268 arg1Of cells,B
R147 T273 T271 arg1Of cells,The
R148 T273 T272 arg1Of cells,B
R149 T273 T274 arg1Of cells,were
R150 T273 T275 arg2Of cells,found
R151 T273 T277 arg1Of cells,express
R152 T275 T274 arg2Of found,were
R153 T275 T285 arg1Of found,and
R154 T277 T275 arg3Of express,found
R155 T277 T276 arg1Of express,to
R156 T280 T281 arg1Of I,and
R157 T282 T281 arg2Of type,and
R158 T284 T277 arg2Of receptors,express
R159 T284 T278 arg1Of receptors,BMP
R160 T284 T279 arg1Of receptors,type
R161 T284 T280 arg1Of receptors,I
R162 T284 T282 arg1Of receptors,type
R163 T284 T283 arg1Of receptors,II
R164 T286 T288 arg1Of BMP-6,induced
R165 T288 T285 arg2Of induced,and
R166 T288 T287 arg1Of induced,rapidly
R167 T289 T288 arg2Of phosphorylation,induced
R168 T289 T290 arg1Of phosphorylation,of
R169 T291 T290 arg2Of Smad1/5/8,of
R170 T294 T295 arg1Of Smad-phosphorylation,was
R171 T294 T296 arg2Of Smad-phosphorylation,followed
R172 T296 T292 arg1Of followed,Furthermore
R173 T296 T293 arg1Of followed,","
R174 T296 T295 arg2Of followed,was
R175 T296 T305 arg1Of followed,","
R176 T296 T306 arg1Of followed,whereas
R177 T298 T296 arg1Of upregulation,followed
R178 T298 T297 arg2Of upregulation,by
R179 T298 T299 arg1Of upregulation,of
R180 T301 T300 arg1Of mRNA,Id1
R181 T301 T302 arg1Of mRNA,and
R182 T302 T299 arg2Of and,of
R183 T304 T302 arg2Of protein,and
R184 T304 T303 arg1Of protein,Id1
R185 T307 T308 arg1Of Id2,and
R186 T309 T308 arg2Of Id3,and
R187 T310 T307 arg1Of expression,Id2
R188 T310 T309 arg1Of expression,Id3
R189 T310 T311 arg1Of expression,was
R190 T310 T313 arg2Of expression,affected
R191 T313 T306 arg2Of affected,whereas
R192 T313 T311 arg2Of affected,was
R193 T313 T312 arg1Of affected,not
R194 T316 T317 arg1Of we,found
R195 T317 T314 arg1Of found,Furthermore
R196 T317 T315 arg1Of found,","
R197 T319 T320 arg1Of BMP-6,had
R198 T320 T317 arg2Of had,found
R199 T320 T318 arg1Of had,that
R200 T320 T325 arg1Of had,in
R201 T323 T320 arg2Of effect,had
R202 T323 T321 arg1Of effect,an
R203 T323 T322 arg1Of effect,antiproliferative
R204 T325 T324 arg1Of in,both
R205 T326 T327 arg1Of naïve,(
R206 T326 T330 arg1Of naïve,and
R207 T328 T327 arg2Of CD19+CD27-,(
R208 T329 T327 arg3Of ),(
R209 T332 T330 arg2Of B,and
R210 T332 T331 arg1Of B,memory
R2101 T2653 T2654 arg1Of BMP-6,inhibits
R2102 T2656 T2655 arg1Of induced,anti-IgM
R2103 T2657 T2654 arg2Of proliferation,inhibits
R2104 T2657 T2656 arg1Of proliferation,induced
R2105 T2657 T2658 arg1Of proliferation,of
R2106 T2661 T2658 arg2Of cells,of
R2107 T2661 T2659 arg1Of cells,human
R2108 T2661 T2660 arg1Of cells,B
R2109 T2663 T2662 arg1Of effects,The
R211 T333 T325 arg2Of cells,in
R2110 T2663 T2664 arg1Of effects,of
R2111 T2663 T2666 arg1Of effects,on
R2112 T2663 T2672 arg1Of effects,prompted
R2113 T2665 T2664 arg2Of BMP-6,of
R2114 T2667 T2668 arg1Of normal,and
R2115 T2669 T2668 arg2Of neoplastic,and
R2116 T2671 T2666 arg2Of cells,on
R2117 T2671 T2667 arg1Of cells,normal
R2118 T2671 T2669 arg1Of cells,neoplastic
R2119 T2671 T2670 arg1Of cells,hematopoietic
R212 T333 T326 arg1Of cells,naïve
R2120 T2673 T2672 arg2Of us,prompted
R2121 T2673 T2675 arg1Of us,investigate
R2122 T2675 T2672 arg3Of investigate,prompted
R2123 T2675 T2674 arg1Of investigate,to
R2124 T2677 T2675 arg2Of effects,investigate
R2125 T2677 T2676 arg1Of effects,the
R2126 T2677 T2678 arg1Of effects,of
R2127 T2677 T2680 arg1Of effects,on
R2128 T2679 T2678 arg2Of BMP-6,of
R2129 T2684 T2680 arg2Of cells,on
R213 T333 T332 arg1Of cells,B
R2130 T2684 T2681 arg1Of cells,normal
R2131 T2684 T2682 arg1Of cells,human
R2132 T2684 T2683 arg1Of cells,B
R2133 T2686 T2685 arg1Of experiments,All
R2134 T2686 T2687 arg1Of experiments,in
R2135 T2686 T2690 arg1Of experiments,were
R2136 T2686 T2691 arg2Of experiments,performed
R2137 T2689 T2687 arg2Of study,in
R2138 T2689 T2688 arg1Of study,this
R2139 T2691 T2690 arg2Of performed,were
R214 T333 T334 arg1Of cells,(
R2140 T2691 T2692 arg1Of performed,under
R2141 T2691 T2695 arg1Of performed,as
R2142 T2694 T2692 arg2Of conditions,under
R2143 T2694 T2693 arg1Of conditions,serum-free
R2144 T2696 T2697 arg1Of FCS,has
R2145 T2696 T2698 arg1Of FCS,been
R2146 T2696 T2699 arg2Of FCS,shown
R2147 T2696 T2701 arg1Of FCS,interfere
R2148 T2699 T2695 arg2Of shown,as
R2149 T2699 T2697 arg2Of shown,has
R215 T333 T337 arg2Of cells,stimulated
R2150 T2699 T2698 arg2Of shown,been
R2151 T2701 T2699 arg3Of interfere,shown
R2152 T2701 T2700 arg1Of interfere,to
R2153 T2701 T2702 arg1Of interfere,with
R2154 T2703 T2702 arg2Of BMP-signalling,with
R2155 T2703 T2704 arg1Of BMP-signalling,[
R2156 T2703 T2707 arg1Of BMP-signalling,(
R2157 T2705 T2704 arg2Of 14,[
R2158 T2706 T2704 arg3Of ],[
R2159 T2709 T2707 arg2Of observations,(
R216 T335 T334 arg2Of CD19+CD27+,(
R2160 T2709 T2708 arg1Of observations,own
R2161 T2710 T2707 arg3Of ),(
R2162 T2712 T2711 arg1Of study,To
R2163 T2714 T2712 arg2Of effect,study
R2164 T2714 T2713 arg1Of effect,the
R2165 T2714 T2715 arg1Of effect,of
R2166 T2714 T2717 arg1Of effect,on
R2167 T2716 T2715 arg2Of BMP-6,of
R2168 T2718 T2717 arg2Of proliferation,on
R2169 T2720 T2721 arg1Of B-cells,from
R217 T336 T334 arg3Of ),(
R2170 T2720 T2724 arg1Of B-cells,were
R2171 T2720 T2725 arg2Of B-cells,stimulated
R2172 T2723 T2721 arg2Of volunteers,from
R2173 T2723 T2722 arg1Of volunteers,healthy
R2174 T2725 T2711 modOf stimulated,To
R2175 T2725 T2719 arg1Of stimulated,","
R2176 T2725 T2724 arg2Of stimulated,were
R2177 T2725 T2726 arg1Of stimulated,with
R2178 T2727 T2728 arg1Of anti-IgM,and/or
R2179 T2728 T2726 arg2Of and/or,with
R218 T337 T338 arg1Of stimulated,with
R2180 T2728 T2730 arg1Of and/or,in
R2181 T2729 T2728 arg2Of CD40L,and/or
R2182 T2732 T2733 arg1Of presence,or
R2183 T2733 T2730 arg2Of or,in
R2184 T2733 T2731 arg1Of or,the
R2185 T2733 T2735 arg1Of or,of
R2186 T2733 T2737 arg1Of or,for
R2187 T2734 T2733 arg2Of absence,or
R2188 T2736 T2735 arg2Of BMP-6,of
R2189 T2739 T2737 arg2Of days,for
R219 T339 T340 arg1Of anti-IgM,alone
R2190 T2739 T2738 arg1Of days,three
R2191 T2740 T2741 arg1Of We,found
R2192 T2743 T2744 arg1Of BMP-6,led
R2193 T2744 T2741 arg2Of led,found
R2194 T2744 T2742 arg1Of led,that
R2195 T2744 T2745 arg1Of led,to
R2196 T2747 T2748 arg1Of 35,%
R2197 T2750 T2745 arg2Of reduction,to
R2198 T2750 T2746 arg1Of reduction,a
R2199 T2750 T2747 arg1Of reduction,35
R220 T339 T341 arg1Of anti-IgM,or
R2200 T2750 T2749 arg1Of reduction,mean
R2201 T2750 T2751 arg1Of reduction,of
R2202 T2755 T2751 arg2Of synthesis,of
R2203 T2755 T2752 arg1Of synthesis,anti-IgM-
R2204 T2755 T2753 arg2Of synthesis,induced
R2205 T2755 T2754 arg1Of synthesis,DNA
R2206 T2755 T2756 arg1Of synthesis,(
R2207 T2757 T2756 arg2Of n,(
R2208 T2757 T2758 arg1Of n,=
R2209 T2758 T2759 arg1Of =,8
R221 T341 T338 arg2Of or,with
R2210 T2758 T2760 arg1Of =,;
R2211 T2761 T2760 arg2Of p,;
R2212 T2761 T2762 arg1Of p,≤
R2213 T2761 T2764 arg1Of p,","
R2214 T2763 T2762 arg2Of 0.0002,≤
R2215 T2766 T2764 arg2Of 1A,","
R2216 T2766 T2765 arg1Of 1A,Figure
R2217 T2767 T2756 arg3Of ),(
R2218 T2769 T2768 arg1Of results,Similar
R2219 T2769 T2770 arg1Of results,were
R222 T344 T341 arg2Of action,or
R2220 T2769 T2771 arg2Of results,obtained
R2221 T2771 T2770 arg2Of obtained,were
R2222 T2771 T2772 arg1Of obtained,for
R2223 T2774 T2772 arg2Of cells,for
R2224 T2774 T2773 arg1Of cells,B
R2225 T2774 T2775 arg2Of cells,treated
R2226 T2775 T2776 arg1Of treated,with
R2227 T2777 T2778 arg1Of anti-IgM,and
R2228 T2778 T2776 arg2Of and,with
R2229 T2778 T2780 arg1Of and,(
R223 T344 T342 arg1Of action,the
R2230 T2779 T2778 arg2Of CD40L,and
R2231 T2782 T2781 arg1Of %,26
R2232 T2783 T2782 arg1Of mean,%
R2233 T2784 T2780 arg2Of reduction,(
R2234 T2784 T2783 arg1Of reduction,mean
R2235 T2784 T2785 arg1Of reduction,","
R2236 T2784 T2789 arg1Of reduction,;
R2237 T2786 T2785 arg2Of n,","
R2238 T2786 T2787 arg1Of n,=
R2239 T2787 T2788 arg1Of =,6
R224 T344 T343 arg2Of action,combined
R2240 T2790 T2791 arg1Of p,≤
R2241 T2791 T2789 arg2Of ≤,;
R2242 T2792 T2791 arg2Of 0.023,≤
R2243 T2793 T2780 arg3Of ),(
R2244 T2796 T2794 arg1Of inhibition,The
R2245 T2796 T2795 arg1Of inhibition,BMP-6-induced
R2246 T2796 T2797 arg1Of inhibition,of
R2247 T2796 T2799 arg1Of inhibition,was
R2248 T2796 T2800 arg1Of inhibition,dose-dependent
R2249 T2798 T2797 arg2Of proliferation,of
R225 T344 T345 arg1Of action,of
R2250 T2800 T2799 arg2Of dose-dependent,was
R2251 T2800 T2801 arg1Of dose-dependent,in
R2252 T2805 T2802 arg1Of cells,both
R2253 T2805 T2803 arg1Of cells,peripheral
R2254 T2805 T2804 arg1Of cells,B
R2255 T2805 T2806 arg1Of cells,(
R2256 T2805 T2810 arg1Of cells,and
R2257 T2808 T2806 arg2Of 1B,(
R2258 T2808 T2807 arg1Of 1B,Figure
R2259 T2809 T2806 arg3Of ),(
R226 T346 T347 arg1Of anti-IgM,and
R2260 T2810 T2801 arg2Of and,in
R2261 T2816 T2810 arg2Of Ramos,and
R2262 T2816 T2811 arg1Of Ramos,the
R2263 T2816 T2812 arg1Of Ramos,Burkitt
R2264 T2816 T2813 arg1Of Ramos,lymphoma
R2265 T2816 T2814 arg1Of Ramos,cell
R2266 T2816 T2815 arg1Of Ramos,line
R2267 T2816 T2817 arg1Of Ramos,(
R2268 T2818 T2819 arg1Of 40,%
R2269 T2820 T2817 arg2Of reduction,(
R227 T347 T345 arg2Of and,of
R2270 T2820 T2818 arg1Of reduction,40
R2271 T2820 T2821 arg1Of reduction,of
R2272 T2820 T2824 arg1Of reduction,","
R2273 T2823 T2821 arg2Of synthesis,of
R2274 T2823 T2822 arg1Of synthesis,DNA
R2275 T2826 T2824 arg2Of 1C,","
R2276 T2826 T2825 arg1Of 1C,Figure
R2277 T2827 T2817 arg3Of ),(
R2278 T2830 T2828 arg1Of effects,The
R2279 T2830 T2829 arg1Of effects,BMP-6
R228 T348 T347 arg2Of CD40L,and
R2280 T2830 T2831 arg1Of effects,could
R2281 T2830 T2832 arg1Of effects,be
R2282 T2830 T2833 arg2Of effects,reversed
R2283 T2833 T2831 arg2Of reversed,could
R2284 T2833 T2832 arg2Of reversed,be
R2285 T2835 T2833 arg1Of addition,reversed
R2286 T2835 T2834 arg2Of addition,by
R2287 T2835 T2836 arg1Of addition,of
R2288 T2840 T2836 arg2Of Noggin,of
R2289 T2840 T2837 arg1Of Noggin,the
R229 T351 T352 arg1Of BMP-6,induced
R2290 T2840 T2838 arg1Of Noggin,extracellular
R2291 T2840 T2839 arg1Of Noggin,inhibitor
R2292 T2840 T2841 arg1Of Noggin,(
R2293 T2843 T2841 arg2Of 1D,(
R2294 T2843 T2842 arg1Of 1D,Figure
R2295 T2844 T2841 arg3Of ),(
R2296 T2848 T2847 arg1Of combination,a
R2297 T2848 T2849 arg1Of combination,of
R2298 T2848 T2858 arg1Of combination,neutralized
R2299 T2854 T2855 arg1Of BMP-RIB-Fc,and
R230 T352 T349 arg1Of induced,Additionally
R2300 T2855 T2849 arg2Of and,of
R2301 T2855 T2850 arg1Of and,the
R2302 T2855 T2851 arg1Of and,soluble
R2303 T2855 T2852 arg1Of and,BMP
R2304 T2855 T2853 arg1Of and,receptors
R2305 T2856 T2855 arg2Of BMP-RII-Fc,and
R2306 T2858 T2845 arg1Of neutralized,Similarly
R2307 T2858 T2846 arg1Of neutralized,","
R2308 T2858 T2857 arg1Of neutralized,also
R2309 T2860 T2858 arg2Of effects,neutralized
R231 T352 T350 arg1Of induced,","
R2310 T2860 T2859 arg1Of effects,the
R2311 T2860 T2861 arg1Of effects,of
R2312 T2860 T2863 arg1Of effects,(
R2313 T2862 T2861 arg2Of BMP-6,of
R2314 T2864 T2863 arg2Of data,(
R2315 T2864 T2866 arg2Of data,shown
R2316 T2866 T2865 arg1Of shown,not
R2317 T2867 T2863 arg3Of ),(
R2318 T2870 T2871 arg1Of we,wanted
R2319 T2870 T2873 arg1Of we,test
R232 T354 T352 arg2Of death,induced
R2320 T2871 T2868 arg1Of wanted,Next
R2321 T2871 T2869 arg1Of wanted,","
R2322 T2873 T2871 arg2Of test,wanted
R2323 T2873 T2872 arg1Of test,to
R2324 T2875 T2876 arg1Of BMP-6,had
R2325 T2876 T2873 arg2Of had,test
R2326 T2876 T2874 arg1Of had,whether
R2327 T2878 T2876 arg2Of effect,had
R2328 T2878 T2877 arg1Of effect,different
R2329 T2878 T2879 arg1Of effect,on
R233 T354 T353 arg1Of death,cell
R2330 T2880 T2881 arg1Of naïve,and
R2331 T2882 T2881 arg2Of memory,and
R2332 T2884 T2879 arg2Of cells,on
R2333 T2884 T2880 arg1Of cells,naïve
R2334 T2884 T2882 arg1Of cells,memory
R2335 T2884 T2883 arg1Of cells,B
R2336 T2885 T2886 arg1Of Naïve,(
R2337 T2885 T2889 arg1Of Naïve,and
R2338 T2887 T2886 arg2Of CD19+CD27-,(
R2339 T2888 T2886 arg3Of ),(
R234 T354 T355 arg1Of death,in
R2340 T2890 T2889 arg2Of memory,and
R2341 T2890 T2896 modOf memory,were
R2342 T2892 T2891 arg2Of CD19+CD27+,(
R2343 T2893 T2891 arg3Of ),(
R2344 T2895 T2891 arg1Of cells,(
R2345 T2895 T2894 arg1Of cells,B
R2346 T2895 T2896 arg1Of cells,were
R2347 T2895 T2897 arg2Of cells,isolated
R2348 T2895 T2914 arg2Of cells,tested
R2349 T2897 T2898 arg1Of isolated,from
R235 T359 T355 arg2Of cells,in
R2350 T2897 T2913 arg1Of isolated,and
R2351 T2900 T2898 arg2Of blood,from
R2352 T2900 T2899 arg1Of blood,peripheral
R2353 T2900 T2901 arg1Of blood,by
R2354 T2903 T2901 arg2Of sorting,by
R2355 T2903 T2902 arg1Of sorting,cell
R2356 T2903 T2904 arg1Of sorting,of
R2357 T2908 T2904 arg2Of cells,of
R2358 T2908 T2905 arg1Of cells,immunobead-isolated
R2359 T2908 T2906 arg1Of cells,CD19+
R236 T359 T356 arg2Of cells,activated
R2360 T2908 T2907 arg1Of cells,B
R2361 T2908 T2909 arg1Of cells,[
R2362 T2910 T2909 arg2Of 15,[
R2363 T2911 T2909 arg3Of ],[
R2364 T2913 T2896 arg2Of and,were
R2365 T2913 T2912 arg1Of and,","
R2366 T2914 T2913 arg2Of tested,and
R2367 T2914 T2915 arg1Of tested,for
R2368 T2917 T2915 arg2Of capacity,for
R2369 T2917 T2916 arg1Of capacity,their
R237 T359 T357 arg1Of cells,memory
R2370 T2917 T2918 modOf capacity,to
R2371 T2919 T2918 arg1Of proliferate,to
R2372 T2919 T2920 arg1Of proliferate,in
R2373 T2922 T2920 arg2Of presence,in
R2374 T2922 T2921 arg1Of presence,the
R2375 T2922 T2923 arg1Of presence,of
R2376 T2924 T2923 arg2Of BMP-6,of
R2377 T2927 T2928 arg1Of BMP-6,inhibited
R2378 T2928 T2925 arg1Of inhibited,However
R2379 T2928 T2926 arg1Of inhibited,","
R238 T359 T358 arg1Of cells,B
R2380 T2928 T2933 arg1Of inhibited,in
R2381 T2928 T2937 arg1Of inhibited,to
R2382 T2928 T2941 arg1Of inhibited,","
R2383 T2928 T2942 arg1Of inhibited,with
R2384 T2930 T2929 arg1Of induced,anti-IgM
R2385 T2932 T2928 arg2Of synthesis,inhibited
R2386 T2932 T2930 arg1Of synthesis,induced
R2387 T2932 T2931 arg1Of synthesis,DNA
R2388 T2936 T2933 arg2Of subpopulations,in
R2389 T2936 T2934 arg1Of subpopulations,the
R239 T364 T362 arg1Of effect,the
R2390 T2936 T2935 arg1Of subpopulations,two
R2391 T2940 T2937 arg2Of extent,to
R2392 T2940 T2938 arg1Of extent,a
R2393 T2940 T2939 arg1Of extent,similar
R2394 T2945 T2942 arg2Of reduction,with
R2395 T2945 T2943 arg1Of reduction,a
R2396 T2945 T2944 arg1Of reduction,mean
R2397 T2945 T2946 arg1Of reduction,of
R2398 T2945 T2948 arg1Of reduction,of
R2399 T2945 T2951 arg1Of reduction,(
R240 T364 T363 arg1Of effect,antiproliferative
R2400 T2945 T2960 arg1Of reduction,for
R2401 T2947 T2946 arg2Of DNA-synthesis,of
R2402 T2950 T2948 arg2Of %,of
R2403 T2950 T2949 arg1Of %,45
R2404 T2952 T2951 arg2Of n,(
R2405 T2952 T2953 arg1Of n,=
R2406 T2952 T2955 arg1Of n,;
R2407 T2953 T2954 arg1Of =,5
R2408 T2956 T2957 arg1Of p,≤
R2409 T2957 T2955 arg2Of ≤,;
R241 T364 T365 arg1Of effect,of
R2410 T2958 T2957 arg2Of "0,004",≤
R2411 T2959 T2951 arg3Of ),(
R2412 T2963 T2961 arg1Of cells,naïve
R2413 T2963 T2962 arg1Of cells,B
R2414 T2963 T2964 arg1Of cells,and
R2415 T2964 T2960 arg2Of and,for
R2416 T2966 T2964 arg2Of %,and
R2417 T2966 T2965 arg1Of %,48
R2418 T2966 T2967 arg1Of %,(
R2419 T2966 T2976 arg1Of %,for
R242 T364 T367 arg1Of effect,in
R2420 T2968 T2967 arg2Of n,(
R2421 T2968 T2969 arg1Of n,=
R2422 T2968 T2971 arg1Of n,;
R2423 T2969 T2970 arg1Of =,5
R2424 T2972 T2973 arg1Of p,≤
R2425 T2973 T2971 arg2Of ≤,;
R2426 T2974 T2973 arg2Of "0,001",≤
R2427 T2975 T2967 arg3Of ),(
R2428 T2979 T2976 arg2Of cells,for
R2429 T2979 T2977 arg1Of cells,memory
R243 T364 T369 arg1Of effect,was
R2430 T2979 T2978 arg1Of cells,B
R2431 T2979 T2980 arg1Of cells,(
R2432 T2982 T2980 arg2Of 1E,(
R2433 T2982 T2981 arg1Of 1E,Figure
R2434 T2983 T2980 arg3Of ),(
R244 T364 T371 arg2Of effect,neutralized
R245 T366 T365 arg2Of BMP-6,of
R246 T368 T367 arg2Of B-cells,in
R247 T371 T360 arg1Of neutralized,Importantly
R248 T371 T361 arg1Of neutralized,","
R249 T371 T369 arg2Of neutralized,was
R250 T371 T370 arg1Of neutralized,completely
R251 T375 T371 arg1Of antagonist,neutralized
R252 T375 T372 arg2Of antagonist,by
R253 T375 T373 arg1Of antagonist,the
R254 T375 T374 arg1Of antagonist,natural
R255 T375 T376 arg1Of antagonist,","
R256 T377 T376 arg2Of noggin,","
R257 T381 T380 arg1Of cells,B
R258 T381 T382 arg1Of cells,were
R259 T381 T383 arg2Of cells,demonstrated
R260 T381 T385 arg1Of cells,upregulate
R261 T383 T378 arg1Of demonstrated,Furthermore
R262 T383 T379 arg1Of demonstrated,","
R263 T383 T382 arg2Of demonstrated,were
R264 T385 T383 arg3Of upregulate,demonstrated
R265 T385 T384 arg1Of upregulate,to
R266 T385 T388 arg1Of upregulate,upon
R267 T387 T385 arg2Of mRNA,upregulate
R268 T387 T386 arg1Of mRNA,BMP-6
R269 T389 T388 arg2Of stimulation,upon
R270 T389 T390 arg1Of stimulation,with
R271 T391 T390 arg2Of anti-IgM,with
R272 T397 T393 arg2Of cells,In
R273 T397 T394 arg1Of cells,mature
R274 T397 T395 arg1Of cells,human
R275 T397 T396 arg1Of cells,B
R276 T399 T400 arg1Of BMP-6,inhibited
R277 T399 T406 arg1Of BMP-6,induced
R278 T400 T404 arg1Of inhibited,and
R279 T402 T400 arg2Of growth,inhibited
R2795 T3594 T3595 arg1Of BMP-6,induces
R2796 T3597 T3595 arg2Of death,induces
R2797 T3597 T3596 arg1Of death,cell
R2798 T3597 T3598 arg1Of death,in
R2799 T3602 T3599 arg1Of cells,human
R280 T402 T401 arg1Of growth,cell
R2800 T3602 T3600 arg1Of cells,memory
R2801 T3602 T3601 arg1Of cells,B
R2802 T3602 T3603 arg1Of cells,and
R2803 T3603 T3598 arg2Of and,in
R2804 T3605 T3603 arg2Of cells,and
R2805 T3605 T3604 arg1Of cells,Ramos
R2806 T3608 T3609 arg1Of we,wanted
R2807 T3608 T3611 arg1Of we,establish
R2808 T3609 T3606 arg1Of wanted,Next
R2809 T3609 T3607 arg1Of wanted,","
R281 T404 T393 arg1Of and,In
R2810 T3611 T3609 arg2Of establish,wanted
R2811 T3611 T3610 arg1Of establish,to
R2812 T3613 T3615 arg1Of BMP-6,could
R2813 T3613 T3616 arg1Of BMP-6,affect
R2814 T3616 T3611 arg2Of affect,establish
R2815 T3616 T3612 arg1Of affect,whether
R2816 T3616 T3614 arg1Of affect,also
R2817 T3616 T3615 arg2Of affect,could
R2818 T3618 T3616 arg2Of viability,affect
R2819 T3618 T3617 arg1Of viability,the
R282 T404 T398 arg1Of and,","
R2820 T3618 T3619 arg1Of viability,of
R2821 T3622 T3619 arg2Of cells,of
R2822 T3622 T3620 arg1Of cells,normal
R2823 T3622 T3621 arg1Of cells,B
R2824 T3624 T3623 arg1Of viability,Cell
R2825 T3624 T3625 arg1Of viability,was
R2826 T3624 T3626 arg2Of viability,determined
R2827 T3626 T3625 arg2Of determined,was
R2828 T3626 T3634 arg1Of determined,after
R2829 T3629 T3628 arg1Of iodide,propidium
R283 T404 T403 arg1Of and,","
R2830 T3629 T3630 arg1Of iodide,(
R2831 T3631 T3630 arg2Of PI,(
R2832 T3632 T3630 arg3Of ),(
R2833 T3633 T3626 arg1Of staining,determined
R2834 T3633 T3627 arg2Of staining,by
R2835 T3633 T3629 arg1Of staining,iodide
R2836 T3635 T3634 arg2Of culture,after
R2837 T3635 T3636 arg1Of culture,with
R2838 T3635 T3638 arg1Of culture,without
R2839 T3636 T3637 arg1Of with,or
R284 T406 T404 arg2Of induced,and
R2840 T3638 T3637 arg2Of without,or
R2841 T3639 T3636 arg2Of BMP-6,with
R2842 T3639 T3638 arg2Of BMP-6,without
R2843 T3639 T3640 arg1Of BMP-6,for
R2844 T3642 T3640 arg2Of hours,for
R2845 T3642 T3641 arg1Of hours,48
R2846 T3645 T3646 arg1Of BMP-6,showed
R2847 T3646 T3643 arg1Of showed,Interestingly
R2848 T3646 T3644 arg1Of showed,","
R2849 T3646 T3657 arg1Of showed,from
R285 T406 T405 arg1Of induced,rapidly
R2850 T3648 T3650 arg1Of small,but
R2851 T3650 T3649 arg1Of but,","
R2852 T3651 T3650 arg2Of reproducible,but
R2853 T3653 T3646 arg2Of increase,showed
R2854 T3653 T3647 arg1Of increase,a
R2855 T3653 T3648 arg1Of increase,small
R2856 T3653 T3651 arg1Of increase,reproducible
R2857 T3653 T3652 arg1Of increase,mean
R2858 T3653 T3654 arg1Of increase,of
R2859 T3656 T3654 arg2Of death,of
R286 T407 T406 arg2Of phosphorylation,induced
R2860 T3656 T3655 arg1Of death,cell
R2861 T3657 T3671 arg1Of from,in
R2862 T3658 T3659 arg1Of 17,to
R2863 T3660 T3659 arg2Of 23,to
R2864 T3661 T3657 arg2Of %,from
R2865 T3661 T3658 arg1Of %,17
R2866 T3661 T3662 arg1Of %,(
R2867 T3663 T3662 arg2Of n,(
R2868 T3663 T3664 arg1Of n,=
R2869 T3663 T3666 arg1Of n,;
R287 T407 T408 arg1Of phosphorylation,of
R2870 T3664 T3665 arg1Of =,5
R2871 T3667 T3668 arg1Of p,≤
R2872 T3668 T3666 arg2Of ≤,;
R2873 T3669 T3668 arg2Of "0,003",≤
R2874 T3670 T3662 arg3Of ),(
R2875 T3677 T3671 arg2Of cells,in
R2876 T3677 T3672 arg1Of cells,anti-IgM
R2877 T3677 T3673 arg2Of cells,stimulated
R2878 T3677 T3674 arg1Of cells,CD27+
R2879 T3677 T3675 arg1Of cells,memory
R288 T409 T408 arg2Of Smad1/5/8,of
R2880 T3677 T3676 arg1Of cells,B
R2881 T3681 T3680 arg1Of cells,Ramos
R2882 T3681 T3682 arg1Of cells,showed
R2883 T3682 T3678 arg1Of showed,Furthermore
R2884 T3682 T3679 arg1Of showed,","
R2885 T3682 T3689 arg1Of showed,from
R2886 T3685 T3682 arg2Of increase,showed
R2887 T3685 T3683 arg1Of increase,a
R2888 T3685 T3684 arg1Of increase,mean
R2889 T3685 T3686 arg1Of increase,in
R289 T409 T410 arg2Of Smad1/5/8,followed
R2890 T3688 T3686 arg2Of death,in
R2891 T3688 T3687 arg1Of death,cell
R2892 T3690 T3691 arg1Of 20,to
R2893 T3692 T3691 arg2Of 50,to
R2894 T3693 T3689 arg2Of %,from
R2895 T3693 T3690 arg1Of %,20
R2896 T3693 T3694 arg1Of %,(
R2897 T3693 T3706 arg1Of %,after
R2898 T3695 T3694 arg2Of n,(
R2899 T3695 T3696 arg1Of n,=
R290 T413 T410 arg1Of upregulation,followed
R2900 T3695 T3698 arg1Of n,","
R2901 T3695 T3702 arg1Of n,","
R2902 T3696 T3697 arg1Of =,3
R2903 T3699 T3698 arg2Of p,","
R2904 T3699 T3700 arg1Of p,<
R2905 T3700 T3701 arg1Of <,"0,001"
R2906 T3703 T3702 arg2Of figure,","
R2907 T3703 T3704 arg1Of figure,3
R2908 T3705 T3694 arg3Of ),(
R2909 T3708 T3706 arg2Of treatment,after
R291 T413 T411 arg2Of upregulation,by
R2910 T3708 T3707 arg1Of treatment,BMP-6
R2911 T3710 T3709 arg2Of contrast,In
R2912 T3713 T3712 arg1Of death,cell
R2913 T3713 T3714 arg1Of death,of
R2914 T3713 T3718 arg1Of death,(
R2915 T3713 T3731 arg1Of death,or
R2916 T3717 T3714 arg2Of cells,of
R2917 T3717 T3715 arg1Of cells,total
R2918 T3717 T3716 arg1Of cells,CD19+
R2919 T3719 T3720 arg1Of n,=
R292 T413 T412 arg1Of upregulation,an
R2920 T3719 T3722 arg1Of n,;
R2921 T3719 T3724 arg1Of n,≤
R2922 T3720 T3721 arg1Of =,6
R2923 T3723 T3722 arg2Of p,;
R2924 T3724 T3718 arg2Of ≤,(
R2925 T3725 T3724 arg2Of "0,32",≤
R2926 T3725 T3726 arg1Of "0,32",;
R2927 T3727 T3726 arg2Of data,;
R2928 T3727 T3729 arg2Of data,shown
R2929 T3729 T3728 arg1Of shown,not
R293 T413 T414 arg1Of upregulation,of
R2930 T3730 T3718 arg3Of ),(
R2931 T3731 T3736 arg1Of or,was
R2932 T3731 T3739 arg2Of or,affected
R2933 T3735 T3731 arg2Of cells,or
R2934 T3735 T3732 arg1Of cells,CD27-IgG-
R2935 T3735 T3733 arg1Of cells,naïve
R2936 T3735 T3734 arg1Of cells,B
R2937 T3739 T3709 arg1Of affected,In
R2938 T3739 T3711 arg1Of affected,","
R2939 T3739 T3736 arg2Of affected,was
R294 T415 T414 arg2Of Id1,of
R2940 T3739 T3737 arg1Of affected,not
R2941 T3739 T3738 arg1Of affected,significantly
R2942 T3739 T3740 arg1Of affected,(
R2943 T3741 T3740 arg2Of n,(
R2944 T3741 T3742 arg1Of n,=
R2945 T3742 T3743 arg1Of =,5
R2946 T3742 T3744 arg1Of =,;
R2947 T3745 T3744 arg2Of p,;
R2948 T3745 T3746 arg1Of p,≤
R2949 T3745 T3748 arg1Of p,","
R2950 T3747 T3746 arg2Of "0,65",≤
R2951 T3749 T3748 arg2Of figure,","
R2952 T3749 T3750 arg1Of figure,2
R2953 T3751 T3740 arg3Of ),(
R3151 T4061 T4059 arg1Of cells,Human
R3152 T4061 T4060 arg1Of cells,B
R3153 T4061 T4062 arg1Of cells,express
R3154 T4064 T4062 arg2Of receptors,express
R3155 T4064 T4063 arg1Of receptors,BMP-6
R3156 T4066 T4065 arg1Of knowledge,Detailed
R3157 T4066 T4067 arg1Of knowledge,regarding
R3158 T4066 T4076 arg1Of knowledge,is
R3159 T4066 T4079 arg1Of knowledge,available
R3160 T4068 T4067 arg2Of expression,regarding
R3161 T4068 T4069 arg1Of expression,of
R3162 T4068 T4073 arg1Of expression,in
R3163 T4072 T4069 arg2Of receptors,of
R3164 T4072 T4070 arg1Of receptors,different
R3165 T4072 T4071 arg1Of receptors,BMP
R3166 T4075 T4073 arg2Of cells,in
R3167 T4075 T4074 arg1Of cells,B
R3168 T4076 T4077 arg1Of is,currently
R3169 T4076 T4078 arg1Of is,not
R3170 T4079 T4076 arg2Of available,is
R3171 T4082 T4080 arg1Of elucidate,To
R3172 T4082 T4081 arg1Of elucidate,further
R3173 T4084 T4082 arg2Of role,elucidate
R3174 T4084 T4083 arg1Of role,the
R3175 T4084 T4085 arg1Of role,of
R3176 T4084 T4087 arg1Of role,in
R3177 T4086 T4085 arg2Of BMPs,of
R3178 T4090 T4087 arg2Of cells,in
R3179 T4090 T4088 arg1Of cells,human
R3180 T4090 T4089 arg1Of cells,B
R3181 T4092 T4082 arg1Of we,elucidate
R3182 T4092 T4093 arg1Of we,performed
R3183 T4093 T4080 modOf performed,To
R3184 T4093 T4091 arg1Of performed,","
R3185 T4096 T4093 arg2Of analysis,performed
R3186 T4096 T4094 arg1Of analysis,western
R3187 T4096 T4095 arg1Of analysis,blot
R3188 T4096 T4097 arg1Of analysis,for
R3189 T4099 T4100 arg1Of I,and
R3190 T4101 T4100 arg2Of type,and
R3191 T4104 T4097 arg2Of receptors,for
R3192 T4104 T4098 arg1Of receptors,type
R3193 T4104 T4099 arg1Of receptors,I
R3194 T4104 T4101 arg1Of receptors,type
R3195 T4104 T4102 arg1Of receptors,II
R3196 T4104 T4103 arg1Of receptors,BMP
R3197 T4106 T4105 arg1Of analysis,This
R3198 T4106 T4107 arg1Of analysis,revealed
R3199 T4112 T4109 arg1Of receptors,the
R3200 T4112 T4110 arg1Of receptors,type
R3201 T4112 T4111 arg1Of receptors,I
R3202 T4112 T4113 arg1Of receptors,Act-RIA
R3203 T4112 T4115 arg1Of receptors,BMP-RIB
R3204 T4112 T4116 arg1Of receptors,and
R3205 T4113 T4114 arg1Of Act-RIA,","
R3206 T4115 T4114 arg2Of BMP-RIB,","
R3207 T4116 T4124 arg1Of and,are
R3208 T4116 T4125 arg2Of and,expressed
R3209 T4120 T4118 arg1Of receptors,type
R3210 T4120 T4119 arg1Of receptors,II
R3211 T4121 T4122 arg1Of BMP-RII,and
R3212 T4122 T4116 arg2Of and,and
R3213 T4122 T4117 arg1Of and,the
R3214 T4122 T4120 arg1Of and,receptors
R3215 T4123 T4122 arg2Of Act-RIIb,and
R3216 T4125 T4107 arg2Of expressed,revealed
R3217 T4125 T4108 arg1Of expressed,that
R3218 T4125 T4124 arg2Of expressed,are
R3219 T4125 T4126 arg1Of expressed,on
R3220 T4129 T4126 arg2Of B-cells,on
R3221 T4129 T4127 arg1Of B-cells,resting
R3222 T4129 T4128 arg1Of B-cells,human
R3223 T4129 T4130 arg1Of B-cells,(
R3224 T4131 T4130 arg2Of Figure,(
R3225 T4131 T4132 arg1Of Figure,4
R3226 T4133 T4130 arg3Of ),(
R3227 T4135 T4134 arg1Of cells,Ramos
R3228 T4135 T4136 arg1Of cells,expressed
R3229 T4136 T4152 arg1Of expressed,but
R3230 T4136 T4154 arg1Of expressed,weakly
R3231 T4141 T4137 arg1Of Act-RIA,the
R3232 T4141 T4138 arg1Of Act-RIA,type
R3233 T4141 T4139 arg1Of Act-RIA,I
R3234 T4141 T4140 arg1Of Act-RIA,receptors
R3235 T4141 T4142 arg1Of Act-RIA,","
R3236 T4142 T4145 arg1Of ",",and
R3237 T4144 T4142 arg2Of BMP-RIB,","
R3238 T4144 T4143 arg1Of BMP-RIB,weakly
R3239 T4145 T4136 arg2Of and,expressed
R3240 T4150 T4145 arg2Of BMP-RII,and
R3241 T4150 T4146 arg1Of BMP-RII,the
R3242 T4150 T4147 arg1Of BMP-RII,type
R3243 T4150 T4148 arg1Of BMP-RII,II
R3244 T4150 T4149 arg1Of BMP-RII,receptor
R3245 T4152 T4151 arg1Of but,","
R3246 T4154 T4153 arg1Of weakly,more
R3247 T4154 T4155 arg1Of weakly,than
R3248 T4158 T4155 arg2Of cells,than
R3249 T4158 T4156 arg1Of cells,normal
R3250 T4158 T4157 arg1Of cells,B
R3251 T4158 T4159 arg1Of cells,(
R3252 T4160 T4159 arg2Of Figure,(
R3253 T4160 T4161 arg1Of Figure,4
R3254 T4162 T4159 arg3Of ),(
R3255 T4164 T4163 arg1Of cells,HL60
R3256 T4164 T4165 arg1Of cells,were
R3257 T4164 T4166 arg2Of cells,used
R3258 T4166 T4165 arg2Of used,were
R3259 T4166 T4167 arg1Of used,for
R3260 T4168 T4169 arg1Of comparison,and
R3261 T4169 T4167 arg2Of and,for
R3262 T4172 T4173 arg1Of Act-RIA,and
R3263 T4173 T4169 arg2Of and,and
R3264 T4173 T4170 arg1Of and,weakly
R3265 T4173 T4171 arg2Of and,expressed
R3266 T4174 T4173 arg2Of BMP-RII,and
R3267 T4175 T4176 arg1Of Taken,together
R3268 T4179 T4178 arg1Of data,these
R3269 T4179 T4180 arg1Of data,show
R3270 T4180 T4175 modOf show,Taken
R3271 T4180 T4177 arg1Of show,","
R3272 T4185 T4182 arg1Of cells,normal
R3273 T4185 T4183 arg1Of cells,human
R3274 T4185 T4184 arg1Of cells,B
R3275 T4185 T4186 arg1Of cells,and
R3276 T4186 T4189 arg1Of and,express
R3277 T4188 T4186 arg2Of cells,and
R3278 T4188 T4187 arg1Of cells,Ramos
R3279 T4189 T4180 arg2Of express,show
R3280 T4189 T4181 arg1Of express,that
R3281 T4191 T4189 arg2Of set,express
R3282 T4191 T4190 arg1Of set,a
R3283 T4191 T4192 arg1Of set,of
R3284 T4191 T4195 arg1Of set,","
R3285 T4191 T4196 arg1Of set,previously
R3286 T4191 T4197 arg2Of set,shown
R3287 T4191 T4199 arg1Of set,bind
R3288 T4194 T4192 arg2Of receptors,of
R3289 T4194 T4193 arg1Of receptors,BMP
R3290 T4199 T4197 arg3Of bind,shown
R3291 T4199 T4198 arg1Of bind,to
R3292 T4199 T4201 arg1Of bind,[
R3293 T4200 T4199 arg2Of BMP-6,bind
R3294 T4202 T4201 arg2Of 16,[
R3295 T4203 T4201 arg3Of ],[
R3561 T4625 T4626 arg1Of BMP-6,induces
R3562 T4627 T4626 arg2Of phosphorylation,induces
R3563 T4627 T4628 arg1Of phosphorylation,of
R3564 T4629 T4628 arg2Of Smad1/5/8,of
R3565 T4632 T4630 arg2Of binding,Upon
R3566 T4632 T4631 arg1Of binding,ligand
R3567 T4637 T4634 arg1Of receptor,the
R3568 T4637 T4635 arg1Of receptor,type
R3569 T4637 T4636 arg1Of receptor,II
R3570 T4637 T4638 arg1Of receptor,transphosphorylates
R3571 T4637 T4640 arg1Of receptor,activates
R3572 T4638 T4639 arg1Of transphosphorylates,and
R3573 T4639 T4630 arg1Of and,Upon
R3574 T4639 T4633 arg1Of and,","
R3575 T4640 T4639 arg2Of activates,and
R3576 T4644 T4638 arg2Of receptor,transphosphorylates
R3577 T4644 T4640 arg2Of receptor,activates
R3578 T4644 T4641 arg1Of receptor,the
R3579 T4644 T4642 arg1Of receptor,type
R3580 T4644 T4643 arg1Of receptor,I
R3581 T4647 T4645 arg1Of receptors,Type
R3582 T4647 T4646 arg1Of receptors,I
R3583 T4647 T4648 arg1Of receptors,can
R3584 T4647 T4649 arg1Of receptors,signal
R3585 T4649 T4648 arg2Of signal,can
R3586 T4649 T4650 arg1Of signal,via
R3587 T4652 T4650 arg2Of pathways,via
R3588 T4652 T4651 arg1Of pathways,several
R3589 T4653 T4654 arg1Of We,examined
R3590 T4654 T4662 arg1Of examined,","
R3591 T4654 T4663 arg1Of examined,as
R3592 T4656 T4654 arg2Of effect,examined
R3593 T4656 T4655 arg1Of effect,the
R3594 T4656 T4657 arg1Of effect,of
R3595 T4656 T4659 arg1Of effect,on
R3596 T4658 T4657 arg2Of BMP-6,of
R3597 T4661 T4659 arg2Of phosphorylation,on
R3598 T4661 T4660 arg1Of phosphorylation,Smad
R3599 T4665 T4664 arg1Of activation,the
R3600 T4665 T4666 arg1Of activation,of
R3601 T4665 T4668 arg1Of activation,is
R3602 T4665 T4669 arg2Of activation,considered
R3603 T4665 T4671 arg1Of activation,be
R3604 T4667 T4666 arg2Of Smad,of
R3605 T4669 T4663 arg2Of considered,as
R3606 T4669 T4668 arg2Of considered,is
R3607 T4671 T4669 arg3Of be,considered
R3608 T4671 T4670 arg1Of be,to
R3609 T4675 T4671 arg2Of pathway,be
R3610 T4675 T4672 arg1Of pathway,a
R3611 T4675 T4673 arg1Of pathway,major
R3612 T4675 T4674 arg1Of pathway,signalling
R3613 T4675 T4676 arg1Of pathway,for
R3614 T4677 T4676 arg2Of BMPs,for
R3615 T4677 T4678 arg1Of BMPs,[
R3616 T4679 T4678 arg2Of 17,[
R3617 T4680 T4678 arg3Of ],[
R3618 T4682 T4681 arg1Of cells,B
R3619 T4682 T4683 arg1Of cells,were
R3620 T4682 T4684 arg2Of cells,cultured
R3621 T4682 T4692 arg2Of cells,treated
R3622 T4684 T4685 arg1Of cultured,in
R3623 T4684 T4690 arg1Of cultured,and
R3624 T4687 T4685 arg2Of media,in
R3625 T4687 T4686 arg1Of media,serum-free
R3626 T4687 T4688 arg1Of media,over
R3627 T4689 T4688 arg2Of night,over
R3628 T4690 T4683 arg2Of and,were
R3629 T4692 T4690 arg2Of treated,and
R3630 T4692 T4691 arg1Of treated,then
R3631 T4692 T4693 arg1Of treated,with
R3632 T4694 T4693 arg2Of BMP-6,with
R3633 T4694 T4695 arg1Of BMP-6,for
R3634 T4698 T4695 arg2Of points,for
R3635 T4698 T4696 arg1Of points,various
R3636 T4698 T4697 arg1Of points,time
R3637 T4701 T4699 arg1Of lysates,Total
R3638 T4701 T4700 arg1Of lysates,protein
R3639 T4701 T4702 arg1Of lysates,were
R3640 T4701 T4703 arg2Of lysates,prepared
R3641 T4703 T4702 arg2Of prepared,were
R3642 T4703 T4705 arg1Of prepared,and
R3643 T4705 T4704 arg1Of and,","
R3644 T4707 T4706 arg1Of amounts,the
R3645 T4707 T4708 arg1Of amounts,of
R3646 T4707 T4714 arg1Of amounts,were
R3647 T4707 T4715 arg2Of amounts,determined
R3648 T4711 T4708 arg2Of forms,of
R3649 T4711 T4709 arg1Of forms,the
R3650 T4711 T4710 arg1Of forms,phosphorylated
R3651 T4711 T4712 arg1Of forms,of
R3652 T4713 T4712 arg2Of Smad1/5/8,of
R3653 T4715 T4705 arg2Of determined,and
R3654 T4715 T4714 arg2Of determined,were
R3655 T4719 T4715 arg1Of analysis,determined
R3656 T4719 T4716 arg2Of analysis,by
R3657 T4719 T4717 arg1Of analysis,western
R3658 T4719 T4718 arg1Of analysis,blot
R3659 T4722 T4723 arg1Of treatment,with
R3660 T4722 T4727 arg1Of treatment,induced
R3661 T4724 T4725 arg1Of 500,ng/ml
R3662 T4726 T4723 arg2Of BMP-6,with
R3663 T4726 T4724 arg1Of BMP-6,500
R3664 T4728 T4727 arg2Of phosphorylation,induced
R3665 T4728 T4729 arg1Of phosphorylation,of
R3666 T4728 T4732 arg1Of phosphorylation,BMP-6
R3667 T4730 T4729 arg2Of Smad.,of
R3668 T4732 T4731 arg1Of BMP-6,The
R3669 T4734 T4733 arg2Of phosphorylation,induced
R3670 T4734 T4735 arg1Of phosphorylation,was
R3671 T4734 T4736 arg1Of phosphorylation,high
R3672 T4734 T4749 arg1Of phosphorylation,remained
R3673 T4734 T4750 arg1Of phosphorylation,high
R3674 T4735 T4737 arg1Of was,at
R3675 T4735 T4748 arg1Of was,and
R3676 T4736 T4735 arg2Of high,was
R3677 T4741 T4737 arg2Of point,at
R3678 T4741 T4738 arg1Of point,the
R3679 T4741 T4739 arg1Of point,earliest
R3680 T4741 T4740 arg1Of point,time
R3681 T4741 T4742 arg2Of point,tested
R3682 T4742 T4743 arg1Of tested,(
R3683 T4745 T4743 arg2Of minutes,(
R3684 T4745 T4744 arg1Of minutes,15
R3685 T4746 T4743 arg3Of ),(
R3686 T4748 T4720 arg1Of and,Interestingly
R3687 T4748 T4721 arg1Of and,","
R3688 T4748 T4727 arg3Of and,induced
R3689 T4748 T4747 arg1Of and,","
R3690 T4749 T4748 arg2Of remained,and
R3691 T4749 T4751 arg1Of remained,for
R3692 T4750 T4749 arg2Of high,remained
R3693 T4754 T4752 arg1Of 48,at
R3694 T4754 T4753 arg1Of 48,least
R3695 T4755 T4751 arg2Of hours,for
R3696 T4755 T4754 arg1Of hours,48
R3697 T4755 T4756 arg1Of hours,(
R3698 T4757 T4756 arg2Of Figure,(
R3699 T4757 T4758 arg1Of Figure,5
R3700 T4759 T4756 arg3Of ),(
R3701 T4762 T4760 arg1Of phosphorylation,A
R3702 T4762 T4761 arg1Of phosphorylation,similar
R3703 T4762 T4763 arg1Of phosphorylation,was
R3704 T4762 T4764 arg2Of phosphorylation,observed
R3705 T4764 T4763 arg2Of observed,was
R3706 T4764 T4765 arg1Of observed,in
R3707 T4764 T4771 arg1Of observed,in
R3708 T4765 T4769 arg1Of in,but
R3709 T4767 T4765 arg2Of cells,in
R3710 T4767 T4766 arg1Of cells,Ramos
R3711 T4769 T4768 arg1Of but,","
R3712 T4771 T4769 arg2Of in,but
R3713 T4771 T4770 arg1Of in,not
R3714 T4773 T4771 arg2Of cells,in
R3715 T4773 T4772 arg1Of cells,HL60
R3716 T4773 T4774 arg1Of cells,(
R3717 T4775 T4774 arg2Of Figure,(
R3718 T4775 T4776 arg1Of Figure,6
R3719 T4777 T4774 arg3Of ),(
R3720 T4780 T4782 arg1Of we,tested
R3721 T4782 T4778 arg1Of tested,Furthermore
R3722 T4782 T4779 arg1Of tested,","
R3723 T4782 T4781 arg1Of tested,also
R3724 T4788 T4784 arg1Of pathways,other
R3725 T4788 T4785 arg2Of pathways,known
R3726 T4788 T4786 arg1Of pathways,downstream
R3727 T4788 T4787 arg1Of pathways,signalling
R3728 T4788 T4789 arg1Of pathways,of
R3729 T4788 T4791 arg1Of pathways,could
R3730 T4788 T4792 arg1Of pathways,be
R3731 T4788 T4793 arg2Of pathways,triggered
R3732 T4790 T4789 arg2Of BMP-6,of
R3733 T4793 T4782 arg2Of triggered,tested
R3734 T4793 T4783 arg1Of triggered,whether
R3735 T4793 T4791 arg2Of triggered,could
R3736 T4793 T4792 arg2Of triggered,be
R3737 T4795 T4793 arg1Of BMP-6,triggered
R3738 T4795 T4794 arg2Of BMP-6,by
R3739 T4795 T4796 arg1Of BMP-6,in
R3740 T4799 T4796 arg2Of cells,in
R3741 T4799 T4797 arg1Of cells,human
R3742 T4799 T4798 arg1Of cells,B
R3743 T4802 T4803 arg1Of we,did
R3744 T4802 T4805 arg1Of we,observe
R3745 T4805 T4800 arg1Of observe,However
R3746 T4805 T4801 arg1Of observe,","
R3747 T4805 T4803 arg2Of observe,did
R3748 T4805 T4804 arg1Of observe,not
R3749 T4805 T4816 arg1Of observe,upon
R3750 T4808 T4805 arg2Of changes,observe
R3751 T4808 T4806 arg1Of changes,any
R3752 T4808 T4807 arg1Of changes,significant
R3753 T4808 T4809 arg1Of changes,in
R3754 T4811 T4809 arg2Of level,in
R3755 T4811 T4810 arg1Of level,the
R3756 T4811 T4812 arg1Of level,of
R3757 T4813 T4814 arg1Of phospho-STAT3,or
R3758 T4814 T4812 arg2Of or,of
R3759 T4815 T4814 arg2Of phospho-p38,or
R3760 T4818 T4816 arg2Of treatment,upon
R3761 T4818 T4817 arg1Of treatment,BMP-6
R3762 T4818 T4819 arg1Of treatment,of
R3763 T4818 T4822 arg1Of treatment,(
R3764 T4821 T4819 arg2Of cells,of
R3765 T4821 T4820 arg1Of cells,B
R3766 T4823 T4822 arg2Of data,(
R3767 T4823 T4825 arg2Of data,shown
R3768 T4825 T4824 arg1Of shown,not
R3769 T4826 T4822 arg3Of ),(
R4242 T5461 T5462 arg1Of BMP-6,induces
R4243 T5463 T5462 arg2Of upregulation,induces
R4244 T5463 T5464 arg1Of upregulation,of
R4245 T5465 T5464 arg2Of Id1,of
R4246 T5466 T5471 arg2Of Next,explore
R4247 T5468 T5469 arg1Of we,wanted
R4248 T5468 T5471 arg1Of we,explore
R4249 T5469 T5467 arg1Of wanted,","
R4250 T5471 T5469 arg2Of explore,wanted
R4251 T5471 T5470 arg1Of explore,to
R4252 T5471 T5472 arg1Of explore,whether
R4253 T5475 T5474 arg1Of induced,BMP-6
R4254 T5476 T5473 arg1Of phosphorylation,the
R4255 T5476 T5475 arg1Of phosphorylation,induced
R4256 T5476 T5477 arg1Of phosphorylation,of
R4257 T5476 T5481 arg1Of phosphorylation,could
R4258 T5476 T5482 arg1Of phosphorylation,induce
R4259 T5478 T5477 arg2Of Smad,of
R4260 T5478 T5479 arg1Of Smad,1/5/8
R4261 T5482 T5472 arg2Of induce,whether
R4262 T5482 T5480 arg1Of induce,also
R4263 T5482 T5481 arg2Of induce,could
R4264 T5484 T5482 arg2Of changes,induce
R4265 T5484 T5483 arg1Of changes,transcriptional
R4266 T5484 T5485 arg1Of changes,of
R4267 T5487 T5485 arg2Of genes,of
R4268 T5487 T5486 arg1Of genes,target
R4269 T5490 T5488 arg2Of regard,In
R4270 T5490 T5489 arg1Of regard,this
R4271 T5493 T5492 arg1Of inhibitors,the
R4272 T5493 T5494 arg1Of inhibitors,of
R4273 T5493 T5501 arg1Of inhibitors,are
R4274 T5493 T5502 arg2Of inhibitors,considered
R4275 T5493 T5504 arg1Of inhibitors,be
R4276 T5497 T5494 arg2Of proteins,of
R4277 T5497 T5495 arg1Of proteins,DNA
R4278 T5497 T5496 arg1Of proteins,binding
R4279 T5497 T5498 arg1Of proteins,(
R4280 T5499 T5498 arg2Of Ids,(
R4281 T5500 T5498 arg3Of ),(
R4282 T5502 T5488 arg1Of considered,In
R4283 T5502 T5491 arg1Of considered,","
R4284 T5502 T5501 arg2Of considered,are
R4285 T5504 T5502 arg3Of be,considered
R4286 T5504 T5503 arg1Of be,to
R4287 T5504 T5511 arg1Of be,for
R4288 T5505 T5504 arg2Of some,be
R4289 T5505 T5506 arg1Of some,of
R4290 T5510 T5506 arg2Of genes,of
R4291 T5510 T5507 arg1Of genes,the
R4292 T5510 T5508 arg1Of genes,major
R4293 T5510 T5509 arg1Of genes,target
R4294 T5512 T5511 arg2Of Smad-signalling,for
R4295 T5512 T5513 arg1Of Smad-signalling,[
R4296 T5514 T5513 arg2Of 17,[
R4297 T5515 T5513 arg3Of ],[
R4298 T5519 T5518 arg1Of cells,B
R4299 T5519 T5520 arg1Of cells,were
R4300 T5519 T5521 arg2Of cells,pre-incubated
R4301 T5519 T5530 arg2Of cells,cultured
R4302 T5521 T5522 arg1Of pre-incubated,over
R4303 T5521 T5524 arg1Of pre-incubated,in
R4304 T5521 T5528 arg1Of pre-incubated,and
R4305 T5523 T5522 arg2Of night,over
R4306 T5525 T5524 arg2Of X-VIVO,in
R4307 T5525 T5526 arg1Of X-VIVO,15
R4308 T5528 T5516 arg1Of and,Thus
R4309 T5528 T5517 arg1Of and,","
R4310 T5528 T5520 arg2Of and,were
R4311 T5528 T5527 arg1Of and,","
R4312 T5530 T5528 arg2Of cultured,and
R4313 T5530 T5529 arg1Of cultured,then
R4314 T5530 T5531 arg1Of cultured,in
R4315 T5530 T5544 arg1Of cultured,before
R4316 T5532 T5531 arg2Of medium,in
R4317 T5532 T5533 arg1Of medium,alone
R4318 T5532 T5535 arg1Of medium,in
R4319 T5532 T5540 arg1Of medium,for
R4320 T5533 T5534 arg1Of alone,or
R4321 T5535 T5534 arg2Of in,or
R4322 T5537 T5535 arg2Of presence,in
R4323 T5537 T5536 arg1Of presence,the
R4324 T5537 T5538 arg1Of presence,of
R4325 T5539 T5538 arg2Of BMP-6,of
R4326 T5543 T5540 arg2Of points,for
R4327 T5543 T5541 arg1Of points,various
R4328 T5543 T5542 arg1Of points,time
R4329 T5545 T5544 arg2Of preparation,before
R4330 T5545 T5546 arg1Of preparation,of
R4331 T5548 T5546 arg2Of RNA,of
R4332 T5548 T5547 arg1Of RNA,total
R4333 T5550 T5549 arg1Of amount,The
R4334 T5550 T5551 arg1Of amount,of
R4335 T5550 T5554 arg1Of amount,was
R4336 T5550 T5555 arg2Of amount,quantified
R4337 T5553 T5551 arg2Of mRNA,of
R4338 T5553 T5552 arg1Of mRNA,Id1–Id4
R4339 T5555 T5554 arg2Of quantified,was
R4340 T5558 T5555 arg1Of RT-PCR,quantified
R4341 T5558 T5556 arg2Of RT-PCR,by
R4342 T5558 T5557 arg1Of RT-PCR,real-time
R4343 T5561 T5562 arg1Of we,observed
R4344 T5562 T5559 arg1Of observed,Interestingly
R4345 T5562 T5560 arg1Of observed,","
R4346 T5562 T5570 arg1Of observed,in
R4347 T5566 T5562 arg2Of upregulation,observed
R4348 T5566 T5563 arg1Of upregulation,a
R4349 T5566 T5564 arg1Of upregulation,specific
R4350 T5566 T5565 arg1Of upregulation,four-fold
R4351 T5566 T5567 arg1Of upregulation,of
R4352 T5569 T5567 arg2Of mRNA,of
R4353 T5569 T5568 arg1Of mRNA,Id1
R4354 T5573 T5570 arg2Of cells,in
R4355 T5573 T5571 arg1Of cells,BMP-6-treated
R4356 T5573 T5572 arg1Of cells,B
R4357 T5573 T5574 arg1Of cells,(
R4358 T5575 T5574 arg2Of Figure,(
R4359 T5575 T5576 arg1Of Figure,7
R4360 T5577 T5574 arg3Of ),(
R4361 T5579 T5578 arg1Of up-regulation,The
R4362 T5579 T5580 arg1Of up-regulation,of
R4363 T5579 T5583 arg1Of up-regulation,was
R4364 T5579 T5584 arg1Of up-regulation,characteristic
R4365 T5579 T5602 arg1Of up-regulation,returned
R4366 T5582 T5580 arg2Of mRNA,of
R4367 T5582 T5581 arg1Of mRNA,Id1
R4368 T5583 T5590 arg1Of was,","
R4369 T5583 T5591 arg1Of was,with
R4370 T5583 T5596 arg1Of was,after
R4371 T5583 T5601 arg1Of was,and
R4372 T5584 T5583 arg2Of characteristic,was
R4373 T5584 T5585 arg1Of characteristic,of
R4374 T5589 T5585 arg2Of gene,of
R4375 T5589 T5586 arg1Of gene,an
R4376 T5589 T5587 arg1Of gene,early
R4377 T5589 T5588 arg1Of gene,inducible
R4378 T5595 T5591 arg2Of hours,with
R4379 T5595 T5592 arg1Of hours,maximal
R4380 T5595 T5593 arg1Of hours,upregulation
R4381 T5595 T5594 arg1Of hours,two
R4382 T5598 T5596 arg2Of addition,after
R4383 T5598 T5597 arg1Of addition,the
R4384 T5598 T5599 arg1Of addition,of
R4385 T5600 T5599 arg2Of BMP-6,of
R4386 T5602 T5601 arg2Of returned,and
R4387 T5602 T5603 arg1Of returned,to
R4388 T5602 T5605 arg1Of returned,after
R4389 T5604 T5603 arg2Of baseline,to
R4390 T5607 T5605 arg2Of hours,after
R4391 T5607 T5606 arg1Of hours,24
R4392 T5609 T5608 arg2Of contrast,In
R4393 T5613 T5611 arg1Of changes,no
R4394 T5613 T5612 arg1Of changes,significant
R4395 T5613 T5614 arg1Of changes,were
R4396 T5613 T5615 arg2Of changes,observed
R4397 T5615 T5608 arg1Of observed,In
R4398 T5615 T5610 arg1Of observed,","
R4399 T5615 T5614 arg2Of observed,were
R4400 T5615 T5616 arg1Of observed,for
R4401 T5615 T5621 arg1Of observed,","
R4402 T5615 T5622 arg1Of observed,whereas
R4403 T5617 T5618 arg1Of Id2,and
R4404 T5619 T5618 arg2Of Id3,and
R4405 T5620 T5616 arg2Of mRNA,for
R4406 T5620 T5617 arg1Of mRNA,Id2
R4407 T5620 T5619 arg1Of mRNA,Id3
R4408 T5623 T5624 arg1Of Id4-transcripts,were
R4409 T5623 T5626 arg1Of Id4-transcripts,detectable
R4410 T5624 T5622 arg2Of were,whereas
R4411 T5624 T5625 arg1Of were,not
R4412 T5626 T5624 arg2Of detectable,were
R4413 T5626 T5627 arg1Of detectable,(
R4414 T5628 T5629 arg1Of Figure,7
R4415 T5628 T5630 arg1Of Figure,","
R4416 T5630 T5627 arg2Of ",",(
R4417 T5630 T5633 arg2Of ",",shown
R4418 T5631 T5630 arg2Of data,","
R4419 T5633 T5632 arg1Of shown,not
R4420 T5634 T5627 arg3Of ),(
R4421 T5637 T5635 arg1Of analysis,Western
R4422 T5637 T5636 arg1Of analysis,blot
R4423 T5637 T5638 arg1Of analysis,revealed
R4424 T5642 T5640 arg1Of upregulation,the
R4425 T5642 T5641 arg1Of upregulation,BMP-6-induced
R4426 T5642 T5643 arg1Of upregulation,of
R4427 T5642 T5647 arg1Of upregulation,was
R4428 T5642 T5648 arg2Of upregulation,correlated
R4429 T5645 T5643 arg2Of mRNA,of
R4430 T5645 T5644 arg1Of mRNA,Id1
R4431 T5648 T5638 arg2Of correlated,revealed
R4432 T5648 T5639 arg1Of correlated,that
R4433 T5648 T5646 arg1Of correlated,also
R4434 T5648 T5647 arg2Of correlated,was
R4435 T5648 T5649 arg1Of correlated,with
R4436 T5648 T5655 arg1Of correlated,well
R4437 T5650 T5649 arg2Of upregulation,with
R4438 T5650 T5651 arg1Of upregulation,of
R4439 T5653 T5651 arg2Of protein,of
R4440 T5653 T5652 arg1Of protein,Id1
R4441 T5655 T5654 arg1Of well,as
R4442 T5657 T5656 arg1Of increase,The
R4443 T5657 T5658 arg1Of increase,in
R4444 T5657 T5662 arg1Of increase,was
R4445 T5657 T5663 arg1Of increase,detectable
R4446 T5657 T5668 arg1Of increase,increased
R4447 T5661 T5658 arg2Of level,in
R4448 T5661 T5659 arg1Of level,Id1
R4449 T5661 T5660 arg1Of level,protein
R4450 T5662 T5664 arg1Of was,after
R4451 T5662 T5667 arg1Of was,and
R4452 T5663 T5662 arg2Of detectable,was
R4453 T5666 T5664 arg2Of hour,after
R4454 T5666 T5665 arg1Of hour,one
R4455 T5667 T5675 arg1Of and,","
R4456 T5667 T5676 modOf and,showing
R4457 T5668 T5667 arg2Of increased,and
R4458 T5668 T5669 arg1Of increased,until
R4459 T5668 T5672 arg1Of increased,after
R4460 T5671 T5669 arg2Of hours,until
R4461 T5671 T5670 arg1Of hours,24
R4462 T5674 T5672 arg2Of addition,after
R4463 T5674 T5673 arg1Of addition,BMP-6
R4464 T5679 T5676 arg2Of upregulation,showing
R4465 T5679 T5677 arg1Of upregulation,a
R4466 T5679 T5678 arg1Of upregulation,16-fold
R4467 T5679 T5680 arg1Of upregulation,compared
R4468 T5681 T5680 arg2Of with,compared
R4469 T5682 T5681 arg2Of t0,with
R4470 T5682 T5683 arg1Of t0,(
R4471 T5682 T5692 arg1Of t0,(
R4472 T5685 T5683 arg2Of ≤,(
R4473 T5685 T5684 arg1Of ≤,p
R4474 T5685 T5686 arg1Of ≤,0.020
R4475 T5685 T5687 arg1Of ≤,","
R4476 T5688 T5687 arg2Of n,","
R4477 T5688 T5689 arg1Of n,=
R4478 T5688 T5690 arg1Of n,4
R4479 T5691 T5683 arg3Of ),(
R4480 T5693 T5694 arg1Of Figure,8
R4481 T5693 T5695 arg1Of Figure,and
R4482 T5695 T5692 arg2Of and,(
R4483 T5696 T5695 arg2Of 9,and
R4484 T5697 T5692 arg3Of ),(
R4485 T5699 T5698 arg2Of line,In
R4486 T5699 T5700 arg1Of line,with
R4487 T5703 T5700 arg2Of data,with
R4488 T5703 T5701 arg1Of data,the
R4489 T5703 T5702 arg1Of data,mRNA
R4490 T5707 T5705 arg1Of change,no
R4491 T5707 T5706 arg1Of change,consistent
R4492 T5707 T5708 arg1Of change,in
R4493 T5707 T5716 arg1Of change,could
R4494 T5707 T5717 arg1Of change,be
R4495 T5707 T5718 arg2Of change,observed
R4496 T5710 T5708 arg2Of amounts,in
R4497 T5710 T5709 arg1Of amounts,the
R4498 T5710 T5711 arg1Of amounts,of
R4499 T5712 T5713 arg1Of Id2,and
R4500 T5714 T5713 arg2Of Id3,and
R4501 T5715 T5711 arg2Of protein,of
R4502 T5715 T5712 arg1Of protein,Id2
R4503 T5715 T5714 arg1Of protein,Id3
R4504 T5718 T5698 arg1Of observed,In
R4505 T5718 T5704 arg1Of observed,","
R4506 T5718 T5716 arg2Of observed,could
R4507 T5718 T5717 arg2Of observed,be
R4508 T5718 T5719 arg1Of observed,(
R4509 T5720 T5721 arg1Of Figure,8
R4510 T5720 T5722 arg1Of Figure,and
R4511 T5722 T5719 arg2Of and,(
R4512 T5723 T5722 arg2Of 9,and
R4513 T5724 T5719 arg3Of ),(
R4514 T5725 T5726 arg1Of We,were
R4515 T5725 T5727 arg1Of We,able
R4516 T5725 T5729 arg1Of We,block
R4517 T5727 T5726 arg2Of able,were
R4518 T5729 T5727 arg2Of block,able
R4519 T5729 T5728 arg1Of block,to
R4520 T5729 T5734 arg1Of block,with
R4521 T5733 T5729 arg2Of band,block
R4522 T5733 T5730 arg1Of band,the
R4523 T5733 T5731 arg1Of band,Id1
R4524 T5733 T5732 arg1Of band,specific
R4525 T5737 T5734 arg2Of peptide,with
R4526 T5737 T5735 arg1Of peptide,a
R4527 T5737 T5736 arg1Of peptide,blocking
R4528 T5737 T5738 arg1Of peptide,(
R4529 T5739 T5738 arg2Of data,(
R4530 T5739 T5741 arg2Of data,shown
R4531 T5741 T5740 arg1Of shown,not
R4532 T5742 T5738 arg3Of ),(
R4533 T5743 T5744 arg1Of Taken,together
R4534 T5747 T5746 arg1Of data,these
R4535 T5747 T5748 arg1Of data,suggest
R4536 T5748 T5743 modOf suggest,Taken
R4537 T5748 T5745 arg1Of suggest,","
R4538 T5750 T5751 arg1Of Id1,could
R4539 T5750 T5752 arg1Of Id1,be
R4540 T5752 T5749 arg1Of be,that
R4541 T5752 T5751 arg2Of be,could
R4542 T5752 T5767 arg1Of be,","
R4543 T5752 T5768 arg1Of be,whereas
R4544 T5752 T5773 arg1Of be,seem
R4545 T5752 T5775 arg1Of be,be
R4546 T5752 T5776 arg2Of be,involved
R4547 T5756 T5752 arg2Of gene,be
R4548 T5756 T5753 arg1Of gene,a
R4549 T5756 T5754 arg1Of gene,possible
R4550 T5756 T5755 arg1Of gene,target
R4551 T5756 T5757 arg1Of gene,for
R4552 T5758 T5757 arg2Of mediating,for
R4553 T5760 T5758 arg2Of effects,mediating
R4554 T5760 T5759 arg1Of effects,the
R4555 T5760 T5761 arg1Of effects,of
R4556 T5760 T5763 arg1Of effects,in
R4557 T5762 T5761 arg2Of BMP-6,of
R4558 T5766 T5763 arg2Of cells,in
R4559 T5766 T5764 arg1Of cells,human
R4560 T5766 T5765 arg1Of cells,B
R4561 T5769 T5770 arg1Of Id2,and
R4562 T5770 T5768 arg2Of and,whereas
R4563 T5771 T5770 arg2Of Id3,and
R4564 T5773 T5748 arg2Of seem,suggest
R4565 T5773 T5772 arg1Of seem,not
R4566 T5776 T5773 arg2Of involved,seem
R4567 T5776 T5774 arg1Of involved,to
R4568 T5776 T5775 arg2Of involved,be
R5081 T6494 T6493 arg1Of production,BMP-6
R5082 T6494 T6495 arg1Of production,in
R5083 T6497 T6495 arg2Of cells,in
R5084 T6497 T6496 arg1Of cells,B
R5085 T6499 T6498 arg1Of fact,The
R5086 T6501 T6502 arg1Of BMP-6,has
R5087 T6501 T6503 arg1Of BMP-6,been
R5088 T6501 T6504 arg2Of BMP-6,reported
R5089 T6501 T6506 arg1Of BMP-6,act
R5090 T6501 T6522 arg1Of BMP-6,prompted
R5091 T6504 T6502 arg2Of reported,has
R5092 T6504 T6503 arg2Of reported,been
R5093 T6504 T6521 arg1Of reported,","
R5094 T6506 T6504 arg3Of act,reported
R5095 T6506 T6505 arg1Of act,to
R5096 T6506 T6507 arg1Of act,as
R5097 T6510 T6509 arg1Of stimulator,autocrine
R5098 T6510 T6511 arg1Of stimulator,in
R5099 T6510 T6516 arg1Of stimulator,and
R5100 T6512 T6511 arg2Of chondrocytes,in
R5101 T6512 T6513 arg1Of chondrocytes,[
R5102 T6514 T6513 arg2Of 18,[
R5103 T6515 T6513 arg3Of ],[
R5104 T6516 T6507 arg2Of and,as
R5105 T6516 T6508 arg1Of and,an
R5106 T6517 T6516 arg2Of ovarium,and
R5107 T6517 T6518 arg1Of ovarium,[
R5108 T6519 T6518 arg2Of 19,[
R5109 T6520 T6518 arg3Of ],[
R5110 T6521 T6499 arg2Of ",",fact
R5111 T6521 T6500 arg1Of ",",that
R5112 T6522 T6521 arg2Of prompted,","
R5113 T6523 T6522 arg2Of us,prompted
R5114 T6523 T6525 arg1Of us,investigate
R5115 T6525 T6522 arg3Of investigate,prompted
R5116 T6525 T6524 arg1Of investigate,to
R5117 T6530 T6527 arg1Of cells,normal
R5118 T6530 T6528 arg1Of cells,human
R5119 T6530 T6529 arg1Of cells,B
R5120 T6530 T6531 arg1Of cells,could
R5121 T6530 T6532 arg1Of cells,produce
R5122 T6532 T6525 arg2Of produce,investigate
R5123 T6532 T6526 arg1Of produce,whether
R5124 T6532 T6531 arg2Of produce,could
R5125 T6532 T6534 arg1Of produce,upon
R5126 T6533 T6532 arg2Of BMP-6,produce
R5127 T6535 T6534 arg2Of stimulation,upon
R5128 T6537 T6536 arg1Of cells,Ramos
R5129 T6537 T6538 arg1Of cells,","
R5130 T6537 T6539 arg1Of cells,which
R5131 T6537 T6540 arg1Of cells,have
R5132 T6537 T6541 arg1Of cells,been
R5133 T6537 T6542 arg2Of cells,described
R5134 T6537 T6544 arg1Of cells,express
R5135 T6537 T6552 arg1Of cells,and
R5136 T6542 T6540 arg2Of described,have
R5137 T6542 T6541 arg2Of described,been
R5138 T6544 T6542 arg3Of express,described
R5139 T6544 T6543 arg1Of express,to
R5140 T6544 T6547 arg1Of express,endogenously
R5141 T6544 T6548 arg1Of express,[
R5142 T6546 T6544 arg2Of mRNA,express
R5143 T6546 T6545 arg1Of mRNA,BMP-6
R5144 T6549 T6548 arg2Of 20,[
R5145 T6550 T6548 arg3Of ],[
R5146 T6552 T6551 arg1Of and,","
R5147 T6552 T6559 arg1Of and,served
R5148 T6557 T6552 arg2Of Jurkat,and
R5149 T6557 T6553 arg1Of Jurkat,the
R5150 T6557 T6554 arg1Of Jurkat,T
R5151 T6557 T6555 arg1Of Jurkat,cell
R5152 T6557 T6556 arg1Of Jurkat,line
R5153 T6559 T6558 arg1Of served,","
R5154 T6559 T6560 arg1Of served,as
R5155 T6559 T6565 arg1Of served,","
R5156 T6559 T6566 arg1Of served,respectively
R5157 T6561 T6562 arg1Of positive,and
R5158 T6563 T6562 arg2Of negative,and
R5159 T6564 T6560 arg2Of controls,as
R5160 T6564 T6561 arg1Of controls,positive
R5161 T6564 T6563 arg1Of controls,negative
R5162 T6570 T6567 arg1Of levels,Endogenous
R5163 T6570 T6568 arg1Of levels,BMP-6
R5164 T6570 T6569 arg1Of levels,mRNA
R5165 T6570 T6571 arg1Of levels,in
R5166 T6570 T6575 arg1Of levels,were
R5167 T6570 T6576 arg2Of levels,quantified
R5168 T6574 T6571 arg2Of cells,in
R5169 T6574 T6572 arg1Of cells,normal
R5170 T6574 T6573 arg1Of cells,B
R5171 T6576 T6575 arg2Of quantified,were
R5172 T6576 T6580 arg1Of quantified,after
R5173 T6579 T6576 arg1Of RT-PCR,quantified
R5174 T6579 T6577 arg2Of RT-PCR,by
R5175 T6579 T6578 arg1Of RT-PCR,real-time
R5176 T6581 T6580 arg2Of stimulation,after
R5177 T6581 T6582 arg1Of stimulation,with
R5178 T6583 T6582 arg2Of anti-IgM,with
R5179 T6583 T6584 arg1Of anti-IgM,for
R5180 T6587 T6584 arg2Of points,for
R5181 T6587 T6585 arg1Of points,different
R5182 T6587 T6586 arg1Of points,time
R5183 T6591 T6590 arg1Of up-regulation,the
R5184 T6591 T6592 arg1Of up-regulation,of
R5185 T6591 T6595 arg1Of up-regulation,was
R5186 T6591 T6596 arg1Of up-regulation,characteristic
R5187 T6594 T6592 arg2Of mRNA,of
R5188 T6594 T6593 arg1Of mRNA,BMP-6
R5189 T6595 T6588 arg1Of was,Interestingly
R5190 T6595 T6589 arg1Of was,","
R5191 T6596 T6595 arg2Of characteristic,was
R5192 T6596 T6597 arg1Of characteristic,of
R5193 T6601 T6599 arg1Of inducible,early-to
R5194 T6601 T6600 arg1Of inducible,intermediate
R5195 T6602 T6597 arg2Of gene,of
R5196 T6602 T6598 arg1Of gene,an
R5197 T6602 T6601 arg1Of gene,inducible
R5198 T6602 T6603 arg1Of gene,with
R5199 T6607 T6603 arg2Of hours,with
R5200 T6607 T6604 arg1Of hours,maximal
R5201 T6607 T6605 arg1Of hours,upregulation
R5202 T6607 T6606 arg1Of hours,four
R5203 T6607 T6608 arg1Of hours,after
R5204 T6610 T6608 arg2Of addition,after
R5205 T6610 T6609 arg1Of addition,the
R5206 T6610 T6611 arg1Of addition,of
R5207 T6612 T6611 arg2Of anti-IgM,of
R5208 T6614 T6613 arg1Of level,The
R5209 T6614 T6615 arg1Of level,of
R5210 T6614 T6618 arg1Of level,was
R5211 T6614 T6619 arg1Of level,back
R5212 T6617 T6615 arg2Of mRNA,of
R5213 T6617 T6616 arg1Of mRNA,BMP-6
R5214 T6618 T6622 arg1Of was,after
R5215 T6618 T6625 arg1Of was,upon
R5216 T6619 T6618 arg2Of back,was
R5217 T6619 T6620 arg1Of back,to
R5218 T6621 T6620 arg2Of baseline,to
R5219 T6624 T6622 arg2Of hours,after
R5220 T6624 T6623 arg1Of hours,24
R5221 T6626 T6625 arg2Of stimulation,upon
R5222 T6626 T6627 arg1Of stimulation,(
R5223 T6628 T6627 arg2Of Figure,(
R5224 T6628 T6629 arg1Of Figure,10
R5225 T6630 T6627 arg3Of ),(
R5226 T6634 T6635 arg1Of FCS,and
R5227 T6635 T6633 arg1Of and,both
R5228 T6635 T6638 arg1Of and,induced
R5229 T6637 T6635 arg2Of AB-serum,and
R5230 T6637 T6636 arg1Of AB-serum,human
R5231 T6638 T6631 arg1Of induced,Furthermore
R5232 T6638 T6632 arg1Of induced,","
R5233 T6640 T6638 arg2Of upregulation,induced
R5234 T6640 T6639 arg1Of upregulation,significant
R5235 T6640 T6641 arg1Of upregulation,of
R5236 T6643 T6641 arg2Of mRNA,of
R5237 T6643 T6642 arg1Of mRNA,BMP-6
R5238 T6643 T6644 arg1Of mRNA,(
R5239 T6645 T6644 arg2Of Figure,(
R5240 T6645 T6646 arg1Of Figure,11
R5241 T6647 T6644 arg3Of ),(
R5242 T6653 T6650 arg2Of study,in
R5243 T6653 T6651 arg1Of study,a
R5244 T6653 T6652 arg1Of study,separate
R5245 T6654 T6655 arg1Of we,have
R5246 T6654 T6656 arg1Of we,found
R5247 T6656 T6648 arg1Of found,Interestingly
R5248 T6656 T6649 arg1Of found,","
R5249 T6656 T6650 arg1Of found,in
R5250 T6656 T6655 arg2Of found,have
R5251 T6661 T6658 arg1Of cells,normal
R5252 T6661 T6659 arg1Of cells,human
R5253 T6661 T6660 arg1Of cells,T
R5254 T6661 T6662 arg1Of cells,do
R5255 T6661 T6664 arg1Of cells,express
R5256 T6664 T6656 arg2Of express,found
R5257 T6664 T6657 arg1Of express,that
R5258 T6664 T6662 arg2Of express,do
R5259 T6664 T6663 arg1Of express,not
R5260 T6664 T6667 arg1Of express,after
R5261 T6666 T6664 arg2Of mRNA,express
R5262 T6666 T6665 arg1Of mRNA,BMP-6
R5263 T6668 T6667 arg2Of activation,after
R5264 T6668 T6669 arg1Of activation,(
R5265 T6672 T6670 arg1Of al,Sivertsen
R5266 T6672 T6671 arg1Of al,et
R5267 T6672 T6673 arg1Of al,","
R5268 T6673 T6669 arg2Of ",",(
R5269 T6673 T6675 arg1Of ",",in
R5270 T6674 T6673 arg2Of manuscript,","
R5271 T6676 T6675 arg2Of preparation,in
R5272 T6677 T6669 arg3Of ),(
R5273 T6680 T6681 arg1Of we,wanted
R5274 T6680 T6683 arg1Of we,detect
R5275 T6681 T6678 arg1Of wanted,Next
R5276 T6681 T6679 arg1Of wanted,","
R5277 T6683 T6681 arg2Of detect,wanted
R5278 T6683 T6682 arg1Of detect,to
R5279 T6683 T6686 arg1Of detect,in
R5280 T6685 T6683 arg2Of protein,detect
R5281 T6685 T6684 arg1Of protein,BMP-6
R5282 T6688 T6687 arg1Of B-cells,normal
R5283 T6688 T6689 arg1Of B-cells,and
R5284 T6689 T6686 arg2Of and,in
R5285 T6693 T6692 arg1Of available,commercially
R5286 T6694 T6689 arg2Of antibodies,and
R5287 T6694 T6690 arg2Of antibodies,tested
R5288 T6694 T6691 arg1Of antibodies,various
R5289 T6694 T6693 arg1Of antibodies,available
R5290 T6699 T6697 arg2Of hands,in
R5291 T6699 T6698 arg1Of hands,our
R5292 T6702 T6700 arg1Of antibodies,these
R5293 T6702 T6701 arg1Of antibodies,anti-BMP-6
R5294 T6702 T6703 arg1Of antibodies,did
R5295 T6702 T6705 arg1Of antibodies,recognize
R5296 T6705 T6695 arg1Of recognize,However
R5297 T6705 T6696 arg1Of recognize,","
R5298 T6705 T6697 arg1Of recognize,in
R5299 T6705 T6703 arg2Of recognize,did
R5300 T6705 T6704 arg1Of recognize,only
R5301 T6709 T6706 arg1Of protein,the
R5302 T6709 T6707 arg1Of protein,recombinant
R5303 T6709 T6708 arg1Of protein,BMP-6
R5304 T6709 T6710 arg1Of protein,and
R5305 T6710 T6705 arg2Of and,recognize
R5306 T6714 T6710 arg2Of protein,and
R5307 T6714 T6711 arg1Of protein,not
R5308 T6714 T6712 arg1Of protein,the
R5309 T6714 T6713 arg1Of protein,native
R5970 T7966 T7965 arg1Of studies,Recent
R5971 T7966 T7967 arg1Of studies,have
R5972 T7966 T7968 arg1Of studies,demonstrated
R5973 T7968 T7967 arg2Of demonstrated,have
R5974 T7968 T7993 arg1Of demonstrated,but
R5975 T7971 T7970 arg1Of role,important
R5976 T7971 T7972 arg1Of role,for
R5977 T7971 T7976 arg1Of role,in
R5978 T7971 T7986 arg1Of role,and
R5979 T7975 T7972 arg2Of members,for
R5980 T7975 T7973 arg1Of members,BMP
R5981 T7975 T7974 arg1Of members,superfamily
R5982 T7979 T7977 arg1Of cells,hematopoietic
R5983 T7979 T7978 arg1Of cells,stem
R5984 T7979 T7980 arg1Of cells,","
R5985 T7980 T7976 arg2Of ",",in
R5986 T7982 T7980 arg2Of thymocytes,","
R5987 T7982 T7981 arg1Of thymocytes,early
R5988 T7982 T7983 arg1Of thymocytes,[
R5989 T7984 T7983 arg2Of "6,7",[
R5990 T7985 T7983 arg3Of ],[
R5991 T7986 T7968 arg2Of and,demonstrated
R5992 T7986 T7969 arg1Of and,an
R5993 T7988 T7986 arg2Of malignancies,and
R5994 T7988 T7987 arg1Of malignancies,B-cell
R5995 T7988 T7989 arg1Of malignancies,[
R5996 T7990 T7989 arg2Of "8,11,12",[
R5997 T7991 T7989 arg3Of ],[
R5998 T7993 T7992 arg1Of but,","
R5999 T7995 T7994 arg1Of role,a
R6000 T7995 T7996 arg1Of role,for
R6001 T7995 T8003 arg1Of role,has
R6002 T7995 T8006 arg1Of role,been
R6003 T7995 T8007 arg2Of role,reported
R6004 T7997 T7996 arg2Of BMPs,for
R6005 T7997 T7998 arg1Of BMPs,in
R6006 T8002 T7998 arg2Of cells,in
R6007 T8002 T7999 arg1Of cells,normal
R6008 T8002 T8000 arg1Of cells,human
R6009 T8002 T8001 arg1Of cells,B
R6010 T8007 T7993 arg2Of reported,but
R6011 T8007 T8003 arg2Of reported,has
R6012 T8007 T8004 arg1Of reported,previously
R6013 T8007 T8005 arg1Of reported,not
R6014 T8007 T8006 arg2Of reported,been
R6015 T8010 T8008 arg1Of study,The
R6016 T8010 T8009 arg1Of study,present
R6017 T8010 T8011 arg1Of study,demonstrated
R6018 T8014 T8013 arg1Of antiproliferative,significant
R6019 T8015 T8011 arg2Of effect,demonstrated
R6020 T8015 T8012 arg1Of effect,a
R6021 T8015 T8014 arg1Of effect,antiproliferative
R6022 T8015 T8016 arg1Of effect,of
R6023 T8015 T8018 arg1Of effect,in
R6024 T8017 T8016 arg2Of BMP-6,of
R6025 T8023 T8018 arg2Of cells,in
R6026 T8023 T8019 arg1Of cells,peripheral
R6027 T8023 T8020 arg1Of cells,blood
R6028 T8023 T8021 arg1Of cells,CD19+
R6029 T8023 T8022 arg1Of cells,B
R6030 T8026 T8027 arg1Of BMP-6,induced
R6031 T8027 T8024 arg1Of induced,Additionally
R6032 T8027 T8025 arg1Of induced,","
R6033 T8027 T8030 arg1Of induced,in
R6034 T8027 T8038 arg1Of induced,in
R6035 T8029 T8027 arg2Of death,induced
R6036 T8029 T8028 arg1Of death,cell
R6037 T8030 T8037 arg1Of in,as
R6038 T8034 T8030 arg2Of cells,in
R6039 T8034 T8031 arg1Of cells,CD27+
R6040 T8034 T8032 arg1Of cells,memory
R6041 T8034 T8033 arg1Of cells,B
R6042 T8037 T8035 arg1Of as,as
R6043 T8037 T8036 arg1Of as,well
R6044 T8038 T8037 arg2Of in,as
R6045 T8043 T8038 arg2Of line,in
R6046 T8043 T8039 arg1Of line,a
R6047 T8043 T8040 arg1Of line,Burkitt
R6048 T8043 T8041 arg1Of line,lymphoma
R6049 T8043 T8042 arg1Of line,cell
R6050 T8043 T8044 arg1Of line,(
R6051 T8045 T8044 arg2Of Ramos,(
R6052 T8046 T8044 arg3Of ),(
R6053 T8049 T8050 arg1Of BMP-6,induced
R6054 T8050 T8047 arg1Of induced,Importantly
R6055 T8050 T8048 arg1Of induced,","
R6056 T8052 T8053 arg1Of rapid,and
R6057 T8054 T8053 arg2Of marked,and
R6058 T8055 T8050 arg2Of increase,induced
R6059 T8055 T8051 arg1Of increase,a
R6060 T8055 T8052 arg1Of increase,rapid
R6061 T8055 T8054 arg1Of increase,marked
R6062 T8055 T8056 arg1Of increase,in
R6063 T8058 T8056 arg2Of phosphorylation,in
R6064 T8058 T8057 arg1Of phosphorylation,Smad-1/5/8
R6065 T8063 T8062 arg1Of induced,BMP-6
R6066 T8065 T8061 arg1Of phosphorylation,the
R6067 T8065 T8063 arg1Of phosphorylation,induced
R6068 T8065 T8064 arg1Of phosphorylation,Smad
R6069 T8065 T8066 arg1Of phosphorylation,was
R6070 T8065 T8067 arg2Of phosphorylation,followed
R6071 T8067 T8059 arg1Of followed,Furthermore
R6072 T8067 T8060 arg1Of followed,","
R6073 T8067 T8066 arg2Of followed,was
R6074 T8071 T8067 arg1Of upregulation,followed
R6075 T8071 T8068 arg2Of upregulation,by
R6076 T8071 T8069 arg1Of upregulation,a
R6077 T8071 T8070 arg1Of upregulation,selective
R6078 T8071 T8072 arg1Of upregulation,of
R6079 T8074 T8073 arg1Of mRNA,Id1
R6080 T8074 T8075 arg1Of mRNA,and
R6081 T8075 T8072 arg2Of and,of
R6082 T8078 T8075 arg2Of protein,and
R6083 T8078 T8076 arg1Of protein,subsequent
R6084 T8078 T8077 arg1Of protein,Id1
R6085 T8082 T8079 arg2Of study,In
R6086 T8082 T8080 arg1Of study,the
R6087 T8082 T8081 arg1Of study,present
R6088 T8087 T8084 arg1Of effect,the
R6089 T8087 T8085 arg2Of effect,demonstrated
R6090 T8087 T8086 arg1Of effect,antiproliferative
R6091 T8087 T8088 arg1Of effect,of
R6092 T8087 T8090 arg1Of effect,in
R6093 T8087 T8095 arg1Of effect,was
R6094 T8087 T8096 arg1Of effect,significant
R6095 T8087 T8098 arg1Of effect,dose-dependent
R6096 T8089 T8088 arg2Of BMP-6,of
R6097 T8094 T8090 arg2Of cells,in
R6098 T8094 T8091 arg1Of cells,anti-IgM
R6099 T8094 T8092 arg2Of cells,treated
R6100 T8094 T8093 arg1Of cells,B
R6101 T8095 T8079 arg1Of was,In
R6102 T8095 T8083 arg1Of was,","
R6103 T8096 T8097 arg1Of significant,and
R6104 T8097 T8095 arg2Of and,was
R6105 T8098 T8097 arg2Of dose-dependent,and
R6106 T8103 T8101 arg1Of effect,the
R6107 T8103 T8102 arg1Of effect,anti-proliferative
R6108 T8103 T8104 arg1Of effect,of
R6109 T8103 T8106 arg1Of effect,could
R6110 T8103 T8107 arg1Of effect,be
R6111 T8103 T8109 arg2Of effect,neutralized
R6112 T8103 T8118 arg1Of effect,Noggin.
R6113 T8105 T8104 arg2Of BMP-6,of
R6114 T8109 T8106 arg2Of neutralized,could
R6115 T8109 T8107 arg2Of neutralized,be
R6116 T8109 T8108 arg1Of neutralized,completely
R6117 T8109 T8117 arg1Of neutralized,","
R6118 T8112 T8109 arg1Of use,neutralized
R6119 T8112 T8110 arg2Of use,by
R6120 T8112 T8111 arg1Of use,the
R6121 T8112 T8113 arg1Of use,of
R6122 T8116 T8113 arg2Of inhibitor,of
R6123 T8116 T8114 arg1Of inhibitor,a
R6124 T8116 T8115 arg1Of inhibitor,natural
R6125 T8117 T8099 arg1Of ",",Importantly
R6126 T8117 T8100 arg1Of ",",","
R6127 T8117 T8125 arg1Of ",",","
R6128 T8117 T8126 modOf ",",showing
R6129 T8118 T8117 arg2Of Noggin.,","
R6130 T8119 T8120 arg1Of This,is
R6131 T8119 T8121 arg1Of This,in
R6132 T8120 T8118 arg2Of is,Noggin.
R6133 T8121 T8120 arg2Of in,is
R6134 T8122 T8121 arg2Of line,in
R6135 T8122 T8123 arg1Of line,with
R6136 T8124 T8123 arg2Of others,with
R6137 T8128 T8129 arg1Of Noggin,can
R6138 T8128 T8130 arg1Of Noggin,function
R6139 T8130 T8126 arg2Of function,showing
R6140 T8130 T8127 arg1Of function,that
R6141 T8130 T8129 arg2Of function,can
R6142 T8130 T8131 arg1Of function,as
R6143 T8130 T8135 arg1Of function,[
R6144 T8134 T8131 arg2Of antagonist,as
R6145 T8134 T8132 arg1Of antagonist,a
R6146 T8134 T8133 arg1Of antagonist,BMP-6
R6147 T8136 T8135 arg2Of "21,22",[
R6148 T8137 T8135 arg3Of ],[
R6149 T8139 T8138 arg2Of addition,In
R6150 T8142 T8141 arg1Of combination,the
R6151 T8142 T8143 arg1Of combination,of
R6152 T8142 T8151 arg1Of combination,neutralized
R6153 T8145 T8144 arg1Of BMP-RIB-Fc,soluble
R6154 T8145 T8146 arg1Of BMP-RIB-Fc,and
R6155 T8146 T8143 arg2Of and,of
R6156 T8149 T8146 arg2Of proteins,and
R6157 T8149 T8147 arg1Of proteins,BMP-RII-Fc
R6158 T8149 T8148 arg1Of proteins,fusion
R6159 T8151 T8138 arg1Of neutralized,In
R6160 T8151 T8140 arg1Of neutralized,","
R6161 T8151 T8150 arg1Of neutralized,also
R6162 T8154 T8151 arg2Of effect,neutralized
R6163 T8154 T8152 arg1Of effect,the
R6164 T8154 T8153 arg1Of effect,anti-proliferative
R6165 T8154 T8155 arg1Of effect,of
R6166 T8154 T8157 arg1Of effect,in
R6167 T8156 T8155 arg2Of BMP-6,of
R6168 T8160 T8157 arg2Of cells,in
R6169 T8160 T8158 arg1Of cells,human
R6170 T8160 T8159 arg1Of cells,B
R6171 T8164 T8163 arg1Of for,as
R6172 T8168 T8164 arg2Of members,for
R6173 T8168 T8165 arg1Of members,other
R6174 T8168 T8166 arg1Of members,TGF
R6175 T8168 T8167 arg1Of members,family
R6176 T8171 T8170 arg1Of effects,bifunctional
R6177 T8171 T8172 arg1Of effects,have
R6178 T8171 T8174 arg1Of effects,been
R6179 T8171 T8175 arg2Of effects,demonstrated
R6180 T8175 T8161 arg1Of demonstrated,Interestingly
R6181 T8175 T8162 arg1Of demonstrated,","
R6182 T8175 T8164 arg1Of demonstrated,for
R6183 T8175 T8169 arg1Of demonstrated,","
R6184 T8175 T8172 arg2Of demonstrated,have
R6185 T8175 T8173 arg1Of demonstrated,also
R6186 T8175 T8174 arg2Of demonstrated,been
R6187 T8175 T8176 arg1Of demonstrated,for
R6188 T8177 T8176 arg2Of BMPs,for
R6189 T8179 T8180 arg1Of several,of
R6190 T8179 T8183 arg1Of several,have
R6191 T8179 T8184 arg1Of several,been
R6192 T8179 T8185 arg2Of several,shown
R6193 T8179 T8187 arg1Of several,promote
R6194 T8182 T8180 arg2Of BMPs,of
R6195 T8182 T8181 arg1Of BMPs,the
R6196 T8185 T8178 arg2Of shown,Whereas
R6197 T8185 T8183 arg2Of shown,have
R6198 T8185 T8184 arg2Of shown,been
R6199 T8187 T8185 arg3Of promote,shown
R6200 T8187 T8186 arg1Of promote,to
R6201 T8187 T8189 arg1Of promote,in
R6202 T8188 T8187 arg2Of proliferation,promote
R6203 T8192 T8189 arg2Of types,in
R6204 T8192 T8190 arg1Of types,various
R6205 T8192 T8191 arg1Of types,cell
R6206 T8192 T8193 arg1Of types,including
R6207 T8194 T8193 arg2Of condrocytes,including
R6208 T8194 T8195 arg1Of condrocytes,[
R6209 T8196 T8195 arg2Of 23,[
R6210 T8197 T8195 arg3Of ],[
R6211 T8199 T8200 arg1Of liver,[
R6212 T8199 T8203 arg1Of liver,and
R6213 T8201 T8200 arg2Of 24,[
R6214 T8202 T8200 arg3Of ],[
R6215 T8203 T8216 arg1Of and,has
R6216 T8203 T8217 arg1Of and,been
R6217 T8203 T8218 arg2Of and,reported
R6218 T8205 T8204 arg1Of cells,granulosa
R6219 T8205 T8206 arg1Of cells,[
R6220 T8205 T8209 arg1Of cells,","
R6221 T8207 T8206 arg2Of 25,[
R6222 T8208 T8206 arg3Of ],[
R6223 T8209 T8203 arg2Of ",",and
R6224 T8211 T8210 arg1Of effects,antiproliferative
R6225 T8211 T8212 arg1Of effects,and
R6226 T8212 T8209 arg2Of and,","
R6227 T8213 T8212 arg2Of induction,and
R6228 T8213 T8214 arg1Of induction,of
R6229 T8215 T8214 arg2Of apoptosis,of
R6230 T8218 T8178 arg1Of reported,Whereas
R6231 T8218 T8198 arg1Of reported,","
R6232 T8218 T8216 arg2Of reported,has
R6233 T8218 T8217 arg2Of reported,been
R6234 T8218 T8219 arg1Of reported,for
R6235 T8220 T8221 arg1Of B,and
R6236 T8222 T8221 arg2Of T,and
R6237 T8224 T8219 arg2Of cells,for
R6238 T8224 T8220 arg1Of cells,B
R6239 T8224 T8222 arg1Of cells,T
R6240 T8224 T8223 arg1Of cells,lineage
R6241 T8226 T8225 arg1Of effects,Similar
R6242 T8226 T8227 arg1Of effects,as
R6243 T8226 T8240 arg1Of effects,were
R6244 T8226 T8241 arg2Of effects,demonstrated
R6245 T8228 T8227 arg2Of demonstrated,as
R6246 T8228 T8229 arg1Of demonstrated,for
R6247 T8230 T8229 arg2Of BMP-6,for
R6248 T8230 T8231 arg1Of BMP-6,on
R6249 T8234 T8231 arg2Of cells,on
R6250 T8234 T8232 arg1Of cells,human
R6251 T8234 T8233 arg1Of cells,B
R6252 T8234 T8235 arg1Of cells,in
R6253 T8238 T8235 arg2Of study,in
R6254 T8238 T8236 arg1Of study,the
R6255 T8238 T8237 arg1Of study,present
R6256 T8241 T8239 arg1Of demonstrated,","
R6257 T8241 T8240 arg2Of demonstrated,were
R6258 T8241 T8242 arg1Of demonstrated,for
R6259 T8243 T8244 arg1Of BMP-2,","
R6260 T8244 T8246 arg1Of ",",","
R6261 T8245 T8244 arg2Of 4,","
R6262 T8246 T8248 arg1Of ",",and
R6263 T8247 T8246 arg2Of 6,","
R6264 T8248 T8242 arg2Of and,for
R6265 T8248 T8250 arg1Of and,in
R6266 T8249 T8248 arg2Of -7,and
R6267 T8253 T8250 arg2Of cells,in
R6268 T8253 T8251 arg1Of cells,human
R6269 T8253 T8252 arg1Of cells,myeloma
R6270 T8253 T8254 arg1Of cells,[
R6271 T8255 T8254 arg2Of 9-11,[
R6272 T8256 T8254 arg3Of ],[
R6273 T8258 T8257 arg1Of members,Other
R6274 T8258 T8259 arg1Of members,of
R6275 T8258 T8262 arg1Of members,have
R6276 T8258 T8264 arg1Of members,been
R6277 T8258 T8265 arg2Of members,reported
R6278 T8258 T8267 arg1Of members,induce
R6279 T8258 T8270 arg1Of members,including
R6280 T8261 T8259 arg2Of BMP-family,of
R6281 T8261 T8260 arg1Of BMP-family,the
R6282 T8265 T8262 arg2Of reported,have
R6283 T8265 T8263 arg1Of reported,also
R6284 T8265 T8264 arg2Of reported,been
R6285 T8265 T8269 arg1Of reported,","
R6286 T8265 T8270 modOf reported,including
R6287 T8267 T8265 arg3Of induce,reported
R6288 T8267 T8266 arg1Of induce,to
R6289 T8268 T8267 arg2Of apoptosis,induce
R6290 T8270 T8271 arg1Of including,in
R6291 T8275 T8271 arg2Of cells,in
R6292 T8275 T8272 arg1Of cells,mouse
R6293 T8275 T8273 arg1Of cells,B
R6294 T8275 T8274 arg1Of cells,lineage
R6295 T8275 T8276 arg1Of cells,[
R6296 T8277 T8276 arg2Of 26,[
R6297 T8278 T8276 arg3Of ],[
R6298 T8281 T8282 arg1Of BMP-4,inhibits
R6299 T8282 T8279 arg1Of inhibits,Additionally
R6300 T8282 T8280 arg1Of inhibits,","
R6301 T8282 T8285 arg1Of inhibits,[
R6302 T8284 T8282 arg2Of proliferation,inhibits
R6303 T8284 T8283 arg1Of proliferation,thymocyte
R6304 T8286 T8285 arg2Of 6,[
R6305 T8287 T8285 arg3Of ],[
R6306 T8288 T8289 arg1Of Taken,together
R6307 T8292 T8291 arg1Of data,these
R6308 T8292 T8293 arg1Of data,suggest
R6309 T8293 T8288 modOf suggest,Taken
R6310 T8293 T8290 arg1Of suggest,","
R6311 T8296 T8295 arg1Of role,the
R6312 T8296 T8297 arg1Of role,of
R6313 T8296 T8299 arg1Of role,in
R6314 T8296 T8306 arg1Of role,is
R6315 T8296 T8310 arg1Of role,dependent
R6316 T8298 T8297 arg2Of BMPs,of
R6317 T8301 T8299 arg2Of regulation,in
R6318 T8301 T8300 arg1Of regulation,the
R6319 T8301 T8302 arg1Of regulation,of
R6320 T8303 T8304 arg1Of proliferation,and
R6321 T8304 T8302 arg2Of and,of
R6322 T8305 T8304 arg2Of apoptosis,and
R6323 T8306 T8293 arg2Of is,suggest
R6324 T8306 T8294 arg1Of is,that
R6325 T8310 T8306 arg2Of dependent,is
R6326 T8310 T8307 arg1Of dependent,highly
R6327 T8310 T8308 arg1Of dependent,cell
R6328 T8310 T8309 arg1Of dependent,type
R6329 T8312 T8311 arg1Of examine,To
R6330 T8313 T8312 arg2Of how,examine
R6331 T8314 T8315 arg1Of BMP-6,exerts
R6332 T8315 T8313 arg1Of exerts,how
R6333 T8315 T8319 arg1Of exerts,in
R6334 T8318 T8315 arg2Of effects,exerts
R6335 T8318 T8316 arg1Of effects,its
R6336 T8318 T8317 arg1Of effects,functional
R6337 T8321 T8319 arg2Of cells,in
R6338 T8321 T8320 arg1Of cells,B
R6339 T8323 T8312 arg1Of we,examine
R6340 T8323 T8324 arg1Of we,analysed
R6341 T8324 T8311 modOf analysed,To
R6342 T8324 T8322 arg1Of analysed,","
R6343 T8324 T8328 arg1Of analysed,by
R6344 T8327 T8324 arg2Of expression,analysed
R6345 T8327 T8325 arg1Of expression,BMP
R6346 T8327 T8326 arg1Of expression,receptor
R6347 T8331 T8328 arg2Of analysis,by
R6348 T8331 T8329 arg1Of analysis,western
R6349 T8331 T8330 arg1Of analysis,blot
R6350 T8335 T8332 arg1Of cells,Human
R6351 T8335 T8333 arg1Of cells,peripheral
R6352 T8335 T8334 arg1Of cells,B
R6353 T8335 T8336 arg1Of cells,were
R6354 T8335 T8337 arg2Of cells,found
R6355 T8335 T8339 arg1Of cells,express
R6356 T8337 T8336 arg2Of found,were
R6357 T8339 T8337 arg3Of express,found
R6358 T8339 T8338 arg1Of express,to
R6359 T8345 T8346 arg1Of Act-RIA,and
R6360 T8346 T8340 arg1Of and,the
R6361 T8346 T8341 arg1Of and,BMP
R6362 T8346 T8342 arg1Of and,type
R6363 T8346 T8343 arg1Of and,I
R6364 T8346 T8344 arg1Of and,receptors
R6365 T8346 T8349 arg1Of and,and
R6366 T8347 T8346 arg2Of BMP-RIB,and
R6367 T8349 T8339 arg2Of and,express
R6368 T8349 T8348 arg1Of and,","
R6369 T8352 T8350 arg1Of II-receptors,the
R6370 T8352 T8351 arg1Of II-receptors,type
R6371 T8353 T8354 arg1Of BMP-RII,and
R6372 T8354 T8349 arg2Of and,and
R6373 T8354 T8352 arg1Of and,II-receptors
R6374 T8354 T8356 arg1Of and,","
R6375 T8354 T8357 arg1Of and,which
R6376 T8354 T8358 arg1Of and,signal
R6377 T8355 T8354 arg2Of Act-RIIb,and
R6378 T8358 T8359 arg1Of signal,after
R6379 T8360 T8359 arg2Of binding,after
R6380 T8360 T8361 arg1Of binding,of
R6381 T8363 T8361 arg2Of BMPs,of
R6382 T8363 T8362 arg1Of BMPs,several
R6383 T8363 T8364 arg1Of BMPs,","
R6384 T8363 T8365 arg1Of BMPs,including
R6385 T8366 T8365 arg2Of BMP-6,including
R6386 T8366 T8367 arg1Of BMP-6,[
R6387 T8368 T8367 arg2Of "16,13",[
R6388 T8369 T8367 arg3Of ],[
R6389 T8372 T8370 arg1Of explore,To
R6390 T8372 T8371 arg1Of explore,further
R6391 T8372 T8374 arg1Of explore,induced
R6392 T8373 T8372 arg2Of BMP-6,explore
R6393 T8374 T8376 arg1Of induced,","
R6394 T8375 T8374 arg2Of signalling,induced
R6395 T8377 T8378 arg1Of activation,of
R6396 T8377 T8381 arg1Of activation,is
R6397 T8377 T8382 arg1Of activation,possible
R6398 T8380 T8378 arg2Of pathways,of
R6399 T8380 T8379 arg1Of pathways,several
R6400 T8381 T8376 arg2Of is,","
R6401 T8382 T8381 arg2Of possible,is
R6402 T8386 T8383 arg1Of pathway,The
R6403 T8386 T8384 arg1Of pathway,major
R6404 T8386 T8385 arg1Of pathway,signalling
R6405 T8386 T8387 arg2Of pathway,known
R6406 T8386 T8391 arg1Of pathway,is
R6407 T8387 T8388 arg1Of known,to
R6408 T8389 T8388 arg2Of date,to
R6409 T8391 T8390 arg1Of is,","
R6410 T8392 T8391 arg2Of activation,is
R6411 T8392 T8393 arg1Of activation,of
R6412 T8394 T8393 arg2Of R-Smads,of
R6413 T8394 T8395 arg1Of R-Smads,[
R6414 T8396 T8395 arg2Of "13,27",[
R6415 T8397 T8395 arg3Of ],[
R6416 T8400 T8398 arg2Of respect,In
R6417 T8400 T8399 arg1Of respect,that
R6418 T8402 T8403 arg1Of BMPs,have
R6419 T8402 T8404 arg1Of BMPs,been
R6420 T8402 T8405 arg2Of BMPs,shown
R6421 T8402 T8407 arg1Of BMPs,exert
R6422 T8405 T8398 arg1Of shown,In
R6423 T8405 T8401 arg1Of shown,","
R6424 T8405 T8403 arg2Of shown,have
R6425 T8405 T8404 arg2Of shown,been
R6426 T8407 T8405 arg3Of exert,shown
R6427 T8407 T8406 arg1Of exert,to
R6428 T8407 T8410 arg1Of exert,in
R6429 T8407 T8414 arg1Of exert,via
R6430 T8409 T8407 arg2Of effects,exert
R6431 T8409 T8408 arg1Of effects,antiproliferative
R6432 T8413 T8410 arg2Of cells,in
R6433 T8413 T8411 arg1Of cells,B
R6434 T8413 T8412 arg1Of cells,lineage
R6435 T8415 T8414 arg2Of phosphorylation,via
R6436 T8415 T8416 arg1Of phosphorylation,of
R6437 T8417 T8416 arg2Of R-Smad,of
R6438 T8417 T8418 arg1Of R-Smad,[
R6439 T8419 T8418 arg2Of "11,28",[
R6440 T8420 T8418 arg3Of ],[
R6441 T8423 T8424 arg1Of BMP-2,has
R6442 T8423 T8425 arg1Of BMP-2,been
R6443 T8423 T8426 arg2Of BMP-2,shown
R6444 T8423 T8428 arg1Of BMP-2,induce
R6445 T8426 T8421 arg1Of shown,Furthermore
R6446 T8426 T8422 arg1Of shown,","
R6447 T8426 T8424 arg2Of shown,has
R6448 T8426 T8425 arg2Of shown,been
R6449 T8428 T8426 arg3Of induce,shown
R6450 T8428 T8427 arg1Of induce,to
R6451 T8428 T8435 arg1Of induce,[
R6452 T8429 T8428 arg2Of activation,induce
R6453 T8429 T8430 arg1Of activation,of
R6454 T8429 T8432 arg1Of activation,in
R6455 T8431 T8430 arg2Of STAT3,of
R6456 T8434 T8432 arg2Of cells,in
R6457 T8434 T8433 arg1Of cells,myeloma
R6458 T8436 T8435 arg2Of 9,[
R6459 T8437 T8435 arg3Of ],[
R6460 T8440 T8441 arg1Of phosphorylation,of
R6461 T8440 T8443 arg1Of phosphorylation,was
R6462 T8440 T8445 arg2Of phosphorylation,investigated
R6463 T8442 T8441 arg2Of R-Smad,of
R6464 T8445 T8438 arg1Of investigated,However
R6465 T8445 T8439 arg1Of investigated,","
R6466 T8445 T8443 arg2Of investigated,was
R6467 T8445 T8444 arg1Of investigated,not
R6468 T8445 T8446 arg1Of investigated,in
R6469 T8448 T8446 arg2Of study,in
R6470 T8448 T8447 arg1Of study,that
R6471 T8449 T8450 arg1Of BMP-2,has
R6472 T8449 T8452 arg1Of BMP-2,been
R6473 T8449 T8453 arg2Of BMP-2,shown
R6474 T8449 T8455 arg1Of BMP-2,induce
R6475 T8453 T8450 arg2Of shown,has
R6476 T8453 T8451 arg1Of shown,also
R6477 T8453 T8452 arg2Of shown,been
R6478 T8455 T8453 arg3Of induce,shown
R6479 T8455 T8454 arg1Of induce,to
R6480 T8455 T8459 arg1Of induce,[
R6481 T8456 T8455 arg2Of phosphorylation,induce
R6482 T8456 T8457 arg1Of phosphorylation,of
R6483 T8458 T8457 arg2Of p38,of
R6484 T8460 T8459 arg2Of 29,[
R6485 T8461 T8459 arg3Of ],[
R6486 T8464 T8465 arg1Of phosphorylation,of
R6487 T8464 T8471 arg1Of phosphorylation,represent
R6488 T8466 T8467 arg1Of p38,","
R6489 T8467 T8469 arg1Of ",",and
R6490 T8468 T8467 arg2Of STAT3,","
R6491 T8469 T8465 arg2Of and,of
R6492 T8470 T8469 arg2Of Smad1/5/8,and
R6493 T8471 T8462 arg1Of represent,Thus
R6494 T8471 T8463 arg1Of represent,","
R6495 T8474 T8471 arg2Of pathways,represent
R6496 T8474 T8472 arg1Of pathways,important
R6497 T8474 T8473 arg1Of pathways,BMP-signalling
R6498 T8474 T8475 arg1Of pathways,that
R6499 T8474 T8476 arg1Of pathways,mediated
R6500 T8474 T8487 arg1Of pathways,has
R6501 T8474 T8488 arg1Of pathways,been
R6502 T8474 T8489 arg2Of pathways,reported
R6503 T8476 T8481 arg1Of mediated,and
R6504 T8478 T8476 arg2Of effects,mediated
R6505 T8478 T8477 arg1Of effects,the
R6506 T8478 T8479 arg1Of effects,of
R6507 T8480 T8479 arg2Of BMPs,of
R6508 T8482 T8483 arg1Of even,cross-talk
R6509 T8483 T8484 arg1Of cross-talk,between
R6510 T8486 T8484 arg2Of pathways,between
R6511 T8486 T8485 arg1Of pathways,these
R6512 T8489 T8481 arg2Of reported,and
R6513 T8489 T8482 arg1Of reported,even
R6514 T8489 T8487 arg2Of reported,has
R6515 T8489 T8488 arg2Of reported,been
R6516 T8489 T8490 arg1Of reported,[
R6517 T8491 T8490 arg2Of "29,30",[
R6518 T8492 T8490 arg3Of ],[
R6519 T8496 T8493 arg2Of study,In
R6520 T8496 T8494 arg1Of study,the
R6521 T8496 T8495 arg1Of study,present
R6522 T8498 T8499 arg1Of we,were
R6523 T8498 T8501 arg1Of we,able
R6524 T8498 T8503 arg1Of we,detect
R6525 T8499 T8493 arg1Of were,In
R6526 T8499 T8497 arg1Of were,","
R6527 T8499 T8500 arg1Of were,not
R6528 T8501 T8499 arg2Of able,were
R6529 T8503 T8501 arg2Of detect,able
R6530 T8503 T8502 arg1Of detect,to
R6531 T8505 T8503 arg2Of changes,detect
R6532 T8505 T8504 arg1Of changes,BMP-6-induced
R6533 T8505 T8506 arg1Of changes,in
R6534 T8509 T8506 arg2Of status,in
R6535 T8509 T8507 arg1Of status,the
R6536 T8509 T8508 arg1Of status,phosphorylation
R6537 T8509 T8510 arg1Of status,of
R6538 T8509 T8514 arg1Of status,in
R6539 T8511 T8512 arg1Of STAT3,or
R6540 T8512 T8510 arg2Of or,of
R6541 T8513 T8512 arg2Of p38,or
R6542 T8518 T8514 arg2Of cells,in
R6543 T8518 T8515 arg1Of cells,human
R6544 T8518 T8516 arg1Of cells,peripheral
R6545 T8518 T8517 arg1Of cells,B
R6546 T8522 T8523 arg1Of rapid,and
R6547 T8524 T8523 arg2Of marked,and
R6548 T8525 T8521 arg1Of phosphorylation,a
R6549 T8525 T8522 arg1Of phosphorylation,rapid
R6550 T8525 T8524 arg1Of phosphorylation,marked
R6551 T8525 T8526 arg1Of phosphorylation,of
R6552 T8525 T8528 arg1Of phosphorylation,was
R6553 T8525 T8529 arg2Of phosphorylation,revealed
R6554 T8527 T8526 arg2Of Smad1/5/8,of
R6555 T8529 T8519 arg1Of revealed,Instead
R6556 T8529 T8520 arg1Of revealed,","
R6557 T8529 T8528 arg2Of revealed,was
R6558 T8533 T8530 arg2Of study,In
R6559 T8533 T8531 arg1Of study,a
R6560 T8533 T8532 arg1Of study,parallel
R6561 T8535 T8536 arg1Of we,have
R6562 T8535 T8537 arg1Of we,found
R6563 T8537 T8530 arg1Of found,In
R6564 T8537 T8534 arg1Of found,","
R6565 T8537 T8536 arg2Of found,have
R6566 T8540 T8539 arg1Of BMPs,other
R6567 T8540 T8542 arg1Of BMPs,induced
R6568 T8542 T8537 arg2Of induced,found
R6569 T8542 T8538 arg1Of induced,that
R6570 T8542 T8541 arg1Of induced,also
R6571 T8542 T8546 arg1Of induced,in
R6572 T8543 T8542 arg2Of phosphorylation,induced
R6573 T8543 T8544 arg1Of phosphorylation,of
R6574 T8545 T8544 arg2Of Smad1/5/8,of
R6575 T8549 T8546 arg2Of cells,in
R6576 T8549 T8547 arg1Of cells,peripheral
R6577 T8549 T8548 arg1Of cells,B
R6578 T8549 T8550 arg1Of cells,(
R6579 T8551 T8550 arg2Of data,(
R6580 T8551 T8553 arg2Of data,shown
R6581 T8553 T8552 arg1Of shown,not
R6582 T8554 T8550 arg3Of ),(
R6583 T8555 T8556 arg1Of We,are
R6584 T8555 T8558 arg1Of We,pursuing
R6585 T8555 T8562 arg1Of We,identify
R6586 T8558 T8556 arg2Of pursuing,are
R6587 T8558 T8557 arg1Of pursuing,currently
R6588 T8558 T8561 modOf pursuing,to
R6589 T8560 T8558 arg2Of studies,pursuing
R6590 T8560 T8559 arg1Of studies,microarray
R6591 T8562 T8561 arg1Of identify,to
R6592 T8565 T8564 arg1Of pathways,signalling
R6593 T8565 T8566 arg1Of pathways,and
R6594 T8566 T8562 arg2Of and,identify
R6595 T8566 T8563 arg1Of and,the
R6596 T8566 T8569 arg1Of and,that
R6597 T8566 T8570 arg1Of and,are
R6598 T8566 T8572 arg2Of and,regulated
R6599 T8568 T8566 arg2Of genes,and
R6600 T8568 T8567 arg1Of genes,target
R6601 T8572 T8570 arg2Of regulated,are
R6602 T8572 T8571 arg1Of regulated,differently
R6603 T8576 T8572 arg1Of BMPs,regulated
R6604 T8576 T8573 arg2Of BMPs,by
R6605 T8576 T8574 arg1Of BMPs,the
R6606 T8576 T8575 arg1Of BMPs,various
R6607 T8576 T8577 arg1Of BMPs,in
R6608 T8580 T8577 arg2Of cells,in
R6609 T8580 T8578 arg1Of cells,human
R6610 T8580 T8579 arg1Of cells,B
R6611 T8581 T8582 arg1Of Upregulation,of
R6612 T8581 T8584 arg1Of Upregulation,via
R6613 T8581 T8587 arg1Of Upregulation,is
R6614 T8583 T8582 arg2Of Id1,of
R6615 T8586 T8584 arg2Of phosphorylation,via
R6616 T8586 T8585 arg1Of phosphorylation,Smad1/5/8
R6617 T8587 T8601 arg1Of is,and
R6618 T8590 T8587 arg2Of mechanism,is
R6619 T8590 T8588 arg1Of mechanism,a
R6620 T8590 T8589 arg1Of mechanism,known
R6621 T8590 T8591 arg1Of mechanism,for
R6622 T8593 T8591 arg2Of signalling,for
R6623 T8593 T8592 arg1Of signalling,BMP-6
R6624 T8593 T8594 arg1Of signalling,in
R6625 T8597 T8594 arg2Of systems,in
R6626 T8597 T8595 arg1Of systems,other
R6627 T8597 T8596 arg1Of systems,cell
R6628 T8597 T8598 arg1Of systems,[
R6629 T8599 T8598 arg2Of "31,32",[
R6630 T8600 T8598 arg3Of ],[
R6631 T8602 T8603 arg1Of regulation,of
R6632 T8602 T8605 arg1Of regulation,is
R6633 T8602 T8606 arg2Of regulation,thought
R6634 T8602 T8608 arg1Of regulation,be
R6635 T8604 T8603 arg2Of Id-proteins,of
R6636 T8606 T8601 arg2Of thought,and
R6637 T8606 T8605 arg2Of thought,is
R6638 T8608 T8606 arg3Of be,thought
R6639 T8608 T8607 arg1Of be,to
R6640 T8608 T8614 arg1Of be,[
R6641 T8611 T8608 arg2Of mechanism,be
R6642 T8611 T8609 arg1Of mechanism,an
R6643 T8611 T8610 arg1Of mechanism,important
R6644 T8611 T8612 arg1Of mechanism,for
R6645 T8613 T8612 arg2Of Smad-signalling,for
R6646 T8615 T8614 arg2Of 17,[
R6647 T8616 T8614 arg3Of ],[
R6648 T8620 T8617 arg2Of study,In
R6649 T8620 T8618 arg1Of study,the
R6650 T8620 T8619 arg1Of study,present
R6651 T8624 T8622 arg1Of experiments,real-time
R6652 T8624 T8623 arg1Of experiments,RT-PCR
R6653 T8624 T8625 arg1Of experiments,revealed
R6654 T8625 T8617 arg1Of revealed,In
R6655 T8625 T8621 arg1Of revealed,","
R6656 T8625 T8632 arg1Of revealed,in
R6657 T8625 T8636 arg1Of revealed,","
R6658 T8625 T8637 arg1Of revealed,while
R6659 T8629 T8625 arg2Of upregulation,revealed
R6660 T8629 T8626 arg1Of upregulation,a
R6661 T8629 T8627 arg1Of upregulation,specific
R6662 T8629 T8628 arg1Of upregulation,four-fold
R6663 T8629 T8630 arg1Of upregulation,for
R6664 T8631 T8630 arg2Of Id1,for
R6665 T8635 T8632 arg2Of cells,in
R6666 T8635 T8633 arg1Of cells,BMP-6-treated
R6667 T8635 T8634 arg1Of cells,B
R6668 T8639 T8638 arg1Of amount,the
R6669 T8639 T8640 arg1Of amount,of
R6670 T8639 T8642 arg1Of amount,remained
R6671 T8639 T8643 arg1Of amount,unchanged
R6672 T8641 T8640 arg2Of Id2–Id4,of
R6673 T8642 T8637 arg2Of remained,while
R6674 T8643 T8642 arg2Of unchanged,remained
R6675 T8644 T8646 arg1Of In,with
R6676 T8645 T8644 arg2Of agreement,In
R6677 T8647 T8644 arg3Of this,In
R6678 T8651 T8649 arg1Of analysis,western
R6679 T8651 T8650 arg1Of analysis,blot
R6680 T8651 T8652 arg1Of analysis,demonstrated
R6681 T8652 T8644 arg1Of demonstrated,In
R6682 T8652 T8648 arg1Of demonstrated,","
R6683 T8652 T8658 arg1Of demonstrated,","
R6684 T8652 T8659 arg1Of demonstrated,while
R6685 T8654 T8652 arg2Of upregulation,demonstrated
R6686 T8654 T8653 arg1Of upregulation,an
R6687 T8654 T8655 arg1Of upregulation,of
R6688 T8657 T8655 arg2Of protein,of
R6689 T8657 T8656 arg1Of protein,Id1
R6690 T8661 T8660 arg1Of amount,the
R6691 T8661 T8662 arg1Of amount,of
R6692 T8661 T8668 arg1Of amount,remained
R6693 T8661 T8669 arg1Of amount,unchanged
R6694 T8663 T8664 arg1Of Id2,and
R6695 T8665 T8664 arg2Of Id3,and
R6696 T8667 T8662 arg2Of levels,of
R6697 T8667 T8663 arg1Of levels,Id2
R6698 T8667 T8665 arg1Of levels,Id3
R6699 T8667 T8666 arg1Of levels,protein
R6700 T8668 T8659 arg2Of remained,while
R6701 T8669 T8668 arg2Of unchanged,remained
R6702 T8672 T8673 arg1Of Id1,has
R6703 T8672 T8674 arg1Of Id1,been
R6704 T8672 T8675 arg2Of Id1,considered
R6705 T8672 T8678 arg1Of Id1,be
R6706 T8672 T8679 arg2Of Id1,expressed
R6707 T8675 T8673 arg2Of considered,has
R6708 T8675 T8674 arg2Of considered,been
R6709 T8675 T8691 arg1Of considered,and
R6710 T8679 T8675 arg3Of expressed,considered
R6711 T8679 T8676 arg1Of expressed,not
R6712 T8679 T8677 arg1Of expressed,to
R6713 T8679 T8678 arg2Of expressed,be
R6714 T8679 T8680 arg1Of expressed,in
R6715 T8683 T8680 arg2Of stages,in
R6716 T8683 T8681 arg1Of stages,later
R6717 T8683 T8682 arg1Of stages,developmental
R6718 T8683 T8684 arg1Of stages,than
R6719 T8686 T8684 arg2Of cells,than
R6720 T8686 T8685 arg1Of cells,pro-B
R6721 T8686 T8687 arg1Of cells,[
R6722 T8688 T8687 arg2Of "33,34",[
R6723 T8689 T8687 arg3Of ],[
R6724 T8691 T8670 arg1Of and,Previously
R6725 T8691 T8671 arg1Of and,","
R6726 T8691 T8690 arg1Of and,","
R6727 T8694 T8692 arg1Of expression,its
R6728 T8694 T8693 arg1Of expression,constitutive
R6729 T8694 T8695 arg1Of expression,has
R6730 T8694 T8696 arg1Of expression,been
R6731 T8694 T8697 arg2Of expression,reported
R6732 T8694 T8699 arg1Of expression,impair
R6733 T8697 T8691 arg2Of reported,and
R6734 T8697 T8695 arg2Of reported,has
R6735 T8697 T8696 arg2Of reported,been
R6736 T8699 T8697 arg3Of impair,reported
R6737 T8699 T8698 arg1Of impair,to
R6738 T8699 T8704 arg1Of impair,[
R6739 T8703 T8699 arg2Of development,impair
R6740 T8703 T8700 arg1Of development,mouse
R6741 T8703 T8701 arg1Of development,B
R6742 T8703 T8702 arg1Of development,cell
R6743 T8705 T8704 arg2Of 35,[
R6744 T8706 T8704 arg3Of ],[
R6745 T8710 T8709 arg1Of demonstration,our
R6746 T8710 T8711 arg1Of demonstration,of
R6747 T8710 T8726 arg1Of demonstration,is
R6748 T8710 T8727 arg1Of demonstration,of
R6749 T8714 T8711 arg2Of upregulation,of
R6750 T8714 T8712 arg1Of upregulation,the
R6751 T8714 T8713 arg1Of upregulation,time-dependent
R6752 T8714 T8715 arg1Of upregulation,of
R6753 T8714 T8720 arg1Of upregulation,in
R6754 T8717 T8716 arg1Of mRNA,Id1
R6755 T8717 T8718 arg1Of mRNA,and
R6756 T8718 T8715 arg2Of and,of
R6757 T8719 T8718 arg2Of protein,and
R6758 T8725 T8720 arg2Of cells,in
R6759 T8725 T8721 arg1Of cells,mature
R6760 T8725 T8722 arg1Of cells,normal
R6761 T8725 T8723 arg1Of cells,human
R6762 T8725 T8724 arg1Of cells,B
R6763 T8726 T8707 arg1Of is,Therefore
R6764 T8726 T8708 arg1Of is,","
R6765 T8727 T8726 arg2Of of,is
R6766 T8729 T8727 arg2Of interest,of
R6767 T8729 T8728 arg1Of interest,particular
R6768 T8732 T8730 arg2Of respect,In
R6769 T8732 T8731 arg1Of respect,that
R6770 T8735 T8730 arg1Of is,In
R6771 T8735 T8733 arg1Of is,","
R6772 T8736 T8735 arg2Of noteworthy,is
R6773 T8739 T8738 arg1Of signalling,TGF-β
R6774 T8739 T8740 arg1Of signalling,in
R6775 T8739 T8746 arg1Of signalling,induces
R6776 T8741 T8742 arg1Of early,and
R6777 T8743 T8742 arg2Of mature,and
R6778 T8745 T8740 arg2Of cells,in
R6779 T8745 T8741 arg1Of cells,early
R6780 T8745 T8743 arg1Of cells,mature
R6781 T8745 T8744 arg1Of cells,B
R6782 T8746 T8734 arg1Of induces,it
R6783 T8746 T8735 arg1Of induces,is
R6784 T8746 T8736 arg1Of induces,noteworthy
R6785 T8746 T8737 arg1Of induces,that
R6786 T8748 T8749 arg1Of Id2,and
R6787 T8750 T8749 arg2Of Id3,and
R6788 T8751 T8747 arg1Of expression,both
R6789 T8751 T8748 arg1Of expression,Id2
R6790 T8751 T8750 arg1Of expression,Id3
R6791 T8751 T8752 arg1Of expression,[
R6792 T8751 T8756 arg1Of expression,but
R6793 T8753 T8752 arg2Of "36,37",[
R6794 T8754 T8752 arg3Of ],[
R6795 T8756 T8746 arg2Of but,induces
R6796 T8756 T8755 arg1Of but,","
R6797 T8758 T8756 arg2Of Id1,but
R6798 T8758 T8757 arg1Of Id1,not
R6799 T8758 T8759 arg1Of Id1,(
R6800 T8760 T8759 arg2Of data,(
R6801 T8760 T8762 arg2Of data,shown
R6802 T8762 T8761 arg1Of shown,not
R6803 T8763 T8759 arg3Of ),(
R6804 T8767 T8766 arg1Of results,these
R6805 T8767 T8768 arg1Of results,show
R6806 T8768 T8764 arg1Of show,Interestingly
R6807 T8768 T8765 arg1Of show,","
R6808 T8771 T8770 arg1Of members,various
R6809 T8771 T8772 arg1Of members,of
R6810 T8771 T8776 arg1Of members,regulate
R6811 T8775 T8772 arg2Of family,of
R6812 T8775 T8773 arg1Of family,the
R6813 T8775 T8774 arg1Of family,TGF-β
R6814 T8776 T8768 arg2Of regulate,show
R6815 T8776 T8769 arg1Of regulate,that
R6816 T8776 T8779 arg1Of regulate,differently
R6817 T8778 T8776 arg2Of proteins,regulate
R6818 T8778 T8777 arg1Of proteins,Id
R6819 T8780 T8781 arg1Of Id2,and
R6820 T8781 T8783 arg1Of and,are
R6821 T8781 T8784 arg2Of and,considered
R6822 T8781 T8786 arg1Of and,be
R6823 T8782 T8781 arg2Of Id3,and
R6824 T8784 T8783 arg2Of considered,are
R6825 T8786 T8784 arg3Of be,considered
R6826 T8786 T8785 arg1Of be,to
R6827 T8789 T8786 arg2Of proteins,be
R6828 T8789 T8787 arg1Of proteins,the
R6829 T8789 T8788 arg1Of proteins,Id
R6830 T8789 T8791 arg2Of proteins,expressed
R6831 T8791 T8790 arg1Of expressed,mainly
R6832 T8791 T8792 arg1Of expressed,in
R6833 T8795 T8792 arg2Of cells,in
R6834 T8795 T8793 arg1Of cells,mature
R6835 T8795 T8794 arg1Of cells,B
R6836 T8795 T8796 arg1Of cells,[
R6837 T8797 T8796 arg2Of 38,[
R6838 T8798 T8796 arg3Of ],[
R6839 T8801 T8799 arg1Of study,The
R6840 T8801 T8800 arg1Of study,present
R6841 T8801 T8803 arg1Of study,found
R6842 T8803 T8802 arg1Of found,also
R6843 T8804 T8805 arg1Of Id2,and
R6844 T8805 T8803 arg2Of and,found
R6845 T8805 T8808 arg1Of and,in
R6846 T8805 T8812 arg1Of and,be
R6847 T8805 T8815 arg2Of and,expressed
R6848 T8807 T8805 arg2Of protein,and
R6849 T8807 T8806 arg1Of protein,Id3
R6850 T8810 T8808 arg2Of cells,in
R6851 T8810 T8809 arg1Of cells,B
R6852 T8814 T8813 arg1Of highly,more
R6853 T8815 T8803 arg3Of expressed,found
R6854 T8815 T8811 arg1Of expressed,to
R6855 T8815 T8812 arg2Of expressed,be
R6856 T8815 T8814 arg1Of expressed,highly
R6857 T8815 T8816 arg1Of expressed,than
R6858 T8817 T8816 arg2Of Id1,than
R6859 T8817 T8818 arg1Of Id1,in
R6860 T8821 T8818 arg2Of cells,in
R6861 T8821 T8819 arg1Of cells,resting
R6862 T8821 T8820 arg1Of cells,B
R6863 T8824 T8825 arg1Of BMP-6,did
R6864 T8824 T8827 arg1Of BMP-6,induce
R6865 T8827 T8822 arg1Of induce,However
R6866 T8827 T8823 arg1Of induce,","
R6867 T8827 T8825 arg2Of induce,did
R6868 T8827 T8826 arg1Of induce,not
R6869 T8829 T8827 arg2Of changes,induce
R6870 T8829 T8828 arg1Of changes,significant
R6871 T8829 T8830 arg1Of changes,in
R6872 T8833 T8830 arg2Of expression,in
R6873 T8833 T8831 arg1Of expression,the
R6874 T8833 T8832 arg1Of expression,protein
R6875 T8833 T8834 arg1Of expression,of
R6876 T8835 T8836 arg1Of Id2,and
R6877 T8836 T8834 arg2Of and,of
R6878 T8837 T8836 arg2Of Id3,and
R6879 T8838 T8839 arg1Of It,is
R6880 T8838 T8840 arg2Of It,believed
R6881 T8840 T8839 arg2Of believed,is
R6882 T8843 T8842 arg1Of proteins,Id
R6883 T8843 T8844 arg1Of proteins,block
R6884 T8843 T8847 arg1Of proteins,promote
R6885 T8844 T8846 arg1Of block,and
R6886 T8845 T8844 arg2Of differentiation,block
R6887 T8846 T8840 arg3Of and,believed
R6888 T8846 T8841 arg1Of and,that
R6889 T8846 T8849 arg1Of and,in
R6890 T8847 T8846 arg2Of promote,and
R6891 T8848 T8847 arg2Of proliferation,promote
R6892 T8852 T8849 arg2Of types,in
R6893 T8852 T8850 arg1Of types,various
R6894 T8852 T8851 arg1Of types,cell
R6895 T8852 T8853 arg1Of types,[
R6896 T8854 T8853 arg2Of "39,33",[
R6897 T8855 T8853 arg3Of ],[
R6898 T8857 T8856 arg1Of proteins,Id
R6899 T8857 T8858 arg1Of proteins,act
R69 T191 T192 arg1Of BMP-6,inhibits
R6900 T8857 T8868 arg1Of proteins,forming
R6901 T8858 T8859 arg1Of act,as
R6902 T8858 T8867 arg1Of act,by
R6903 T8861 T8860 arg1Of inhibitors,dominant-negative
R6904 T8861 T8862 arg1Of inhibitors,of
R6905 T8861 T8864 arg1Of inhibitors,and
R6906 T8863 T8862 arg2Of E-proteins,of
R6907 T8864 T8859 arg2Of and,as
R6908 T8866 T8864 arg2Of function,and
R6909 T8866 T8865 arg1Of function,Pax5
R6910 T8868 T8867 arg2Of forming,by
R6911 T8868 T8870 arg1Of forming,with
R6912 T8868 T8873 arg1Of forming,","
R6913 T8868 T8874 modOf forming,making
R6914 T8869 T8868 arg2Of dimers,forming
R6915 T8872 T8870 arg2Of proteins,with
R6916 T8872 T8871 arg1Of proteins,these
R6917 T8875 T8874 arg2Of them,making
R6918 T8875 T8876 arg1Of them,unable
R6919 T8875 T8878 arg1Of them,bind
R6920 T8876 T8874 arg3Of unable,making
R6921 T8878 T8876 arg2Of bind,unable
R6922 T8878 T8877 arg1Of bind,to
R6923 T8879 T8878 arg2Of DNA,bind
R6924 T8880 T8881 arg1Of It,has
R6925 T8880 T8882 arg1Of It,been
R6926 T8880 T8883 arg2Of It,proposed
R6927 T8883 T8881 arg2Of proposed,has
R6928 T8883 T8882 arg2Of proposed,been
R6929 T8886 T8885 arg1Of balance,the
R6930 T8886 T8887 arg1Of balance,among
R6931 T8886 T8894 arg1Of balance,might
R6932 T8886 T8895 arg1Of balance,have
R6933 T8888 T8889 arg1Of E-proteins,","
R6934 T8889 T8891 arg1Of ",",and
R6935 T8890 T8889 arg2Of Pax5,","
R6936 T8891 T8887 arg2Of and,among
R6937 T8893 T8891 arg2Of proteins,and
R6938 T8893 T8892 arg1Of proteins,Id
R6939 T8895 T8883 arg3Of have,proposed
R6940 T8895 T8884 arg1Of have,that
R6941 T8895 T8894 arg2Of have,might
R6942 T8895 T8899 arg1Of have,in
R6943 T8898 T8895 arg2Of role,have
R6944 T8898 T8896 arg1Of role,an
R6945 T8898 T8897 arg1Of role,important
R6946 T8902 T8899 arg2Of cells,in
R6947 T8902 T8900 arg2Of cells,activated
R6948 T8902 T8901 arg1Of cells,B
R6949 T8902 T8903 arg1Of cells,[
R6950 T8904 T8903 arg2Of 38,[
R6951 T8905 T8903 arg3Of ],[
R6952 T8908 T8906 arg2Of respect,In
R6953 T8908 T8907 arg1Of respect,that
R6954 T8910 T8911 arg1Of E-proteins,have
R6955 T8910 T8912 arg1Of E-proteins,been
R6956 T8910 T8913 arg2Of E-proteins,implicated
R6957 T8913 T8906 arg1Of implicated,In
R6958 T8913 T8909 arg1Of implicated,","
R6959 T8913 T8911 arg2Of implicated,have
R6960 T8913 T8912 arg2Of implicated,been
R6961 T8913 T8914 arg1Of implicated,in
R6962 T8913 T8925 arg1Of implicated,at
R6963 T8917 T8918 arg1Of promotion,and
R6964 T8918 T8914 arg2Of and,in
R6965 T8918 T8915 arg1Of and,both
R6966 T8918 T8916 arg1Of and,the
R6967 T8918 T8920 arg1Of and,of
R6968 T8919 T8918 arg2Of inhibition,and
R6969 T8922 T8923 arg1Of survival,and
R6970 T8923 T8920 arg2Of and,of
R6971 T8923 T8921 arg1Of and,cell
R6972 T8924 T8923 arg2Of growth,and
R6973 T8927 T8925 arg2Of points,at
R6974 T8927 T8926 arg1Of points,different
R6975 T8927 T8928 arg1Of points,in
R6976 T8930 T8928 arg2Of development,in
R6977 T8930 T8929 arg1Of development,lymphocyte
R6978 T8930 T8931 arg1Of development,[
R6979 T8932 T8931 arg2Of 40,[
R6980 T8933 T8931 arg3Of ],[
R6981 T8937 T8934 arg1Of death,The
R6982 T8937 T8935 arg1Of death,antiproliferative
R6983 T8937 T8936 arg1Of death,and
R6984 T8937 T8938 arg1Of death,inducing
R6985 T8937 T8951 arg1Of death,is
R6986 T8937 T8953 arg1Of death,in
R6987 T8939 T8938 arg2Of effect,inducing
R6988 T8939 T8940 arg1Of effect,of
R6989 T8939 T8942 arg1Of effect,in
R6990 T8939 T8945 arg1Of effect,with
R6991 T8941 T8940 arg2Of BMP-6,of
R6992 T8944 T8942 arg2Of cells,in
R6993 T8944 T8943 arg1Of cells,B
R6994 T8947 T8945 arg2Of upregulation,with
R6995 T8947 T8946 arg1Of upregulation,concomitant
R6996 T8947 T8948 arg1Of upregulation,of
R6997 T8950 T8948 arg2Of protein,of
R6998 T8950 T8949 arg1Of protein,Id1
R6999 T8951 T8952 arg1Of is,therefore
R70 T192 T199 arg1Of inhibits,;
R7000 T8953 T8951 arg2Of in,is
R7001 T8954 T8953 arg2Of line,in
R7002 T8954 T8955 arg1Of line,with
R7003 T8957 T8955 arg2Of view,with
R7004 T8957 T8956 arg1Of view,the
R7005 T8960 T8959 arg1Of proteins,Id
R7006 T8960 T8961 arg1Of proteins,are
R7007 T8960 T8962 arg2Of proteins,required
R7008 T8962 T8957 arg2Of required,view
R7009 T8962 T8958 arg1Of required,that
R7010 T8962 T8961 arg2Of required,are
R7011 T8962 T8963 arg1Of required,for
R7012 T8962 T8976 arg1Of required,[
R7013 T8965 T8963 arg2Of induction,for
R7014 T8965 T8964 arg1Of induction,the
R7015 T8965 T8966 arg1Of induction,of
R7016 T8965 T8971 arg1Of induction,in
R7017 T8965 T8974 arg1Of induction,by
R7018 T8968 T8967 arg1Of arrest,growth
R7019 T8968 T8969 arg1Of arrest,and
R7020 T8969 T8966 arg2Of and,of
R7021 T8970 T8969 arg2Of apoptosis,and
R7022 T8973 T8971 arg2Of progenitors,in
R7023 T8973 T8972 arg1Of progenitors,B-lymphocyte
R7024 T8975 T8974 arg2Of TGF-β,by
R7025 T8977 T8976 arg2Of 40,[
R7026 T8978 T8976 arg3Of ],[
R7027 T8982 T8981 arg1Of proteins,Id
R7028 T8982 T8983 arg1Of proteins,are
R7029 T8982 T8984 arg2Of proteins,known
R7030 T8984 T8979 arg1Of known,Furthermore
R7031 T8984 T8980 arg1Of known,","
R7032 T8984 T8983 arg2Of known,are
R7033 T8984 T8985 arg1Of known,as
R7034 T8987 T8985 arg2Of parts,as
R7035 T8996 T8994 arg2Of cycle,","
R7036 T8996 T8995 arg1Of cycle,cell
R7037 T8997 T8992 arg2Of and,in
R7038 T8998 T8997 arg2Of tumorigenesis,and
R7039 T8998 T8999 arg1Of tumorigenesis,[
R7040 T8987 T8986 arg1Of parts,important
R7041 T8987 T8988 arg1Of parts,of
R7042 T9000 T8999 arg2Of 32,[
R7043 T8990 T8988 arg2Of pathways,of
R7044 T9001 T8999 arg3Of ],[
R7045 T9002 T9003 arg1Of It,is
R7046 T9002 T9005 arg2Of It,established
R7047 T9005 T9003 arg2Of established,is
R7048 T9005 T9004 arg1Of established,well
R7049 T8990 T8989 arg1Of pathways,signalling
R7050 T8990 T8991 arg2Of pathways,involved
R7051 T9008 T9007 arg1Of members,various
R7052 T9008 T9009 arg1Of members,of
R7053 T9008 T9013 arg1Of members,are
R7054 T9008 T9014 arg2Of members,overexpressed
R7055 T8991 T8992 arg1Of involved,in
R7056 T8993 T8994 arg1Of development,","
R7057 T9012 T9009 arg2Of family,of
R7058 T9012 T9010 arg1Of family,the
R7059 T9012 T9011 arg1Of family,Id
R7060 T9014 T9005 arg3Of overexpressed,established
R7061 T9014 T9006 arg1Of overexpressed,that
R7062 T9014 T9013 arg2Of overexpressed,are
R7063 T9014 T9015 arg1Of overexpressed,in
R7064 T9014 T9022 arg1Of overexpressed,generally
R7065 T9015 T9021 arg1Of in,and
R7066 T9017 T9015 arg2Of range,in
R7067 T9017 T9016 arg1Of range,a
R7068 T9017 T9018 arg1Of range,of
R7069 T9020 T9018 arg2Of tumours,of
R7070 T8994 T8997 arg1Of ",",and
R7071 T9020 T9019 arg1Of tumours,human
R7072 T9022 T9021 arg2Of generally,and
R7073 T9024 T9025 arg1Of Id1,appears
R7074 T9024 T9027 arg1Of Id1,be
R7075 T9093 T9091 arg2Of respect,In
R7076 T9025 T9003 modOf appears,is
R7077 T9025 T9023 arg1Of appears,","
R7078 T9027 T9025 arg2Of be,appears
R7079 T9027 T9026 arg1Of be,to
R7080 T9030 T9027 arg2Of member,be
R7081 T9030 T9028 arg1Of member,the
R7082 T9030 T9029 arg1Of member,family
R7083 T9030 T9033 arg2Of member,overexpressed
R7084 T9032 T9031 arg1Of widely,most
R7085 T9093 T9092 arg1Of respect,this
R7086 T9033 T9032 arg1Of overexpressed,widely
R7087 T9033 T9034 arg1Of overexpressed,in
R7088 T9095 T9096 arg1Of it,is
R7089 T9095 T9106 arg1Of it,resulted
R7090 T9098 T9097 arg2Of interest,of
R7091 T9036 T9034 arg2Of variety,in
R7092 T9036 T9035 arg1Of variety,a
R7093 T9036 T9037 arg1Of variety,of
R7094 T9039 T9037 arg2Of malignancies,of
R7095 T9039 T9038 arg1Of malignancies,human
R7096 T9039 T9040 arg1Of malignancies,[
R7097 T9039 T9043 arg1Of malignancies,","
R7098 T9039 T9044 arg1Of malignancies,including
R7099 T9098 T9099 arg1Of interest,that
R71 T193 T192 arg2Of growth,inhibits
R7100 T9041 T9040 arg2Of 41,[
R7101 T9042 T9040 arg3Of ],[
R7102 T9098 T9100 arg1Of interest,targeted
R7103 T9101 T9100 arg2Of expression,targeted
R7104 T9046 T9044 arg2Of myeloma,including
R7105 T9046 T9045 arg1Of myeloma,multiple
R7106 T9046 T9047 arg1Of myeloma,[
R7107 T9048 T9047 arg2Of "42,32",[
R7108 T9049 T9047 arg3Of ],[
R7109 T9101 T9102 arg1Of expression,of
R7110 T9053 T9052 arg1Of findings,our
R7111 T9053 T9064 arg1Of findings,might
R7112 T9053 T9065 arg1Of findings,be
R7113 T9053 T9066 arg1Of findings,of
R7114 T9103 T9102 arg2Of Id1,of
R7115 T9055 T9056 arg1Of BMP-6,activates
R7116 T9056 T9053 arg2Of activates,findings
R7117 T9056 T9054 arg1Of activates,that
R7118 T9103 T9104 arg1Of Id1,to
R7119 T9059 T9056 arg2Of pathways,activates
R7120 T9059 T9057 arg1Of pathways,intracellular
R7121 T9059 T9058 arg1Of pathways,signalling
R7122 T9059 T9060 arg1Of pathways,in
R7123 T9105 T9104 arg2Of B-lymphocytes,to
R7124 T9063 T9060 arg2Of cells,in
R7125 T9063 T9061 arg1Of cells,human
R7126 T9063 T9062 arg1Of cells,B
R7127 T9106 T9091 arg1Of resulted,In
R7128 T9065 T9050 arg1Of be,Additionally
R7129 T9065 T9051 arg1Of be,","
R7130 T9065 T9064 arg2Of be,might
R7131 T9065 T9070 arg1Of be,in
R7132 T9066 T9065 arg2Of of,be
R7133 T9106 T9094 arg1Of resulted,","
R7134 T9106 T9096 arg2Of resulted,is
R7135 T9106 T9097 arg1Of resulted,of
R7136 T9106 T9107 arg1Of resulted,in
R7137 T9069 T9066 arg2Of significance,of
R7138 T9069 T9067 arg1Of significance,potential
R7139 T9069 T9068 arg1Of significance,pathophysiological
R7140 T9106 T9123 arg1Of resulted,[
R7141 T9111 T9108 arg1Of development,aberrant
R7142 T9071 T9072 arg1Of lymphoma,and
R7143 T9072 T9070 arg2Of and,in
R7144 T9073 T9072 arg2Of inflammation,and
R7145 T9077 T9074 arg1Of expression,High
R7146 T9077 T9075 arg1Of expression,BMP-6
R7147 T9077 T9076 arg1Of expression,mRNA
R7148 T9077 T9078 arg1Of expression,in
R7149 T9077 T9080 arg1Of expression,has
R7150 T9077 T9081 arg1Of expression,been
R7151 T9077 T9082 arg2Of expression,shown
R7152 T9077 T9084 arg1Of expression,correlate
R7153 T9079 T9078 arg2Of DLBCL,in
R7154 T9111 T9109 arg1Of development,B
R7155 T9111 T9110 arg1Of development,cell
R7156 T9082 T9080 arg2Of shown,has
R7157 T9082 T9081 arg2Of shown,been
R7158 T9084 T9082 arg3Of correlate,shown
R7159 T9084 T9083 arg1Of correlate,to
R7160 T9084 T9085 arg1Of correlate,to
R7161 T9111 T9112 arg1Of development,","
R7162 T9087 T9085 arg2Of outcome,to
R7163 T9087 T9086 arg1Of outcome,unfavourable
R7164 T9087 T9088 arg1Of outcome,[
R7165 T9112 T9116 arg1Of ",",and
R7166 T9089 T9088 arg2Of 12,[
R7167 T9114 T9112 arg2Of apoptosis,","
R7168 T9090 T9088 arg3Of ],[
R7169 T9114 T9113 arg1Of apoptosis,massive
R7170 T9116 T9107 arg2Of and,in
R7171 T9116 T9115 arg1Of and,","
R7172 T9118 T9116 arg2Of development,and
R7173 T9189 T9188 arg1Of cells,B
R7174 T9189 T9190 arg1Of cells,are
R7175 T9189 T9191 arg2Of cells,involved
R7176 T9118 T9117 arg1Of development,subsequent
R7177 T9191 T9187 arg2Of involved,where
R7178 T9191 T9190 arg2Of involved,are
R7179 T9118 T9119 arg1Of development,of
R7180 T9192 T9193 arg1Of It,will
R7181 T9192 T9195 arg1Of It,be
R7182 T9192 T9196 arg1Of It,important
R7183 T9122 T9119 arg2Of lymphomas,of
R7184 T9195 T9193 arg2Of be,will
R7185 T9195 T9194 arg1Of be,therefore
R7186 T9195 T9197 modOf be,to
R7187 T9196 T9195 arg2Of important,be
R7188 T9199 T9197 arg1Of elucidate,to
R7189 T9199 T9198 arg1Of elucidate,further
R7190 T9122 T9120 arg1Of lymphomas,B
R7191 T9201 T9199 arg2Of role,elucidate
R7192 T9201 T9200 arg1Of role,the
R7193 T9201 T9202 arg1Of role,of
R7194 T9201 T9204 arg1Of role,in
R7195 T9201 T9208 arg1Of role,by
R7196 T9122 T9121 arg1Of lymphomas,cell
R7197 T9203 T9202 arg2Of Id-1,of
R7198 T9124 T9123 arg2Of 35,[
R7199 T9207 T9204 arg2Of cells,in
R72 T193 T194 arg1Of growth,of
R7200 T9207 T9205 arg1Of cells,human
R7201 T9207 T9206 arg1Of cells,B
R7202 T9125 T9123 arg3Of ],[
R7203 T9209 T9208 arg2Of selective,by
R7204 T9209 T9210 arg1Of selective,over
R7205 T9128 T9129 arg1Of BMP-6,has
R7206 T9211 T9212 arg1Of expression,or
R7207 T9212 T9210 arg2Of or,over
R7208 T9213 T9212 arg2Of inhibition,or
R7209 T9217 T9208 arg3Of expression,by
R7210 T9217 T9214 arg1Of expression,of
R7211 T9217 T9215 arg1Of expression,Id-1
R7212 T9217 T9216 arg1Of expression,gene
R7213 T9128 T9130 arg1Of BMP-6,been
R7214 T9220 T9218 arg2Of role,Given
R7215 T9220 T9219 arg1Of role,the
R7216 T9220 T9221 arg1Of role,of
R7217 T9220 T9223 arg1Of role,in
R7218 T9220 T9228 arg1Of role,demonstrated
R7219 T9128 T9131 arg2Of BMP-6,suggested
R7220 T9222 T9221 arg2Of BMP-6,of
R7221 T9128 T9133 arg1Of BMP-6,play
R7222 T9131 T9129 arg2Of suggested,has
R7223 T9227 T9223 arg2Of cells,in
R7224 T9227 T9224 arg1Of cells,mature
R7225 T9227 T9225 arg1Of cells,human
R7226 T9227 T9226 arg1Of cells,B
R7227 T9228 T9218 modOf demonstrated,Given
R7228 T9229 T9228 arg2Of here,demonstrated
R7229 T9229 T9249 arg2Of here,contribute
R7230 T9131 T9130 arg2Of suggested,been
R7231 T9231 T9232 arg1Of identification,of
R7232 T9231 T9242 arg1Of identification,with
R7233 T9231 T9248 arg1Of identification,might
R7234 T9231 T9249 arg1Of identification,contribute
R7235 T9131 T9142 arg1Of suggested,[
R7236 T9233 T9234 arg1Of BMP-6,producing
R7237 T9131 T9145 arg1Of suggested,and
R7238 T9234 T9237 arg1Of producing,vivo
R7239 T9234 T9238 arg1Of producing,with
R7240 T9235 T9234 arg2Of cells,producing
R7241 T9133 T9131 arg3Of play,suggested
R7242 T9237 T9236 arg1Of vivo,in
R7243 T9133 T9132 arg1Of play,to
R7244 T9239 T9238 arg2Of possibility,with
R7245 T9133 T9136 arg1Of play,in
R7246 T9135 T9133 arg2Of role,play
R7247 T9241 T9232 arg2Of interaction,of
R7248 T9241 T9233 arg1Of interaction,BMP-6
R7249 T9241 T9240 arg1Of interaction,of
R7250 T9243 T9244 arg1Of naïve,and
R7251 T9244 T9242 arg2Of and,with
R7252 T9135 T9134 arg1Of role,a
R7253 T9138 T9136 arg2Of arthritis,in
R7254 T9247 T9244 arg2Of cells,and
R7255 T9247 T9245 arg1Of cells,memory
R7256 T9247 T9246 arg1Of cells,B
R7257 T9249 T9230 arg1Of contribute,","
R7258 T9249 T9248 arg2Of contribute,might
R7259 T9249 T9250 arg1Of contribute,to
R7260 T9138 T9137 arg1Of arthritis,rheumatoid
R7261 T9138 T9139 arg1Of arthritis,(
R7262 T9140 T9139 arg2Of RA,(
R7263 T9252 T9250 arg2Of understanding,to
R7264 T9252 T9251 arg1Of understanding,the
R7265 T9252 T9253 arg1Of understanding,of
R7266 T9141 T9139 arg3Of ),(
R7267 T9257 T9253 arg2Of biology,of
R7268 T9257 T9254 arg1Of biology,mature
R7269 T9257 T9255 arg1Of biology,B
R7270 T9257 T9256 arg1Of biology,cell
R7271 T9143 T9142 arg2Of "43,44",[
R7272 T9261 T9258 arg1Of expression,High
R7273 T9261 T9259 arg1Of expression,BMP-6
R7274 T9261 T9260 arg1Of expression,mRNA
R7275 T9261 T9262 arg1Of expression,in
R7276 T9261 T9264 arg1Of expression,has
R7277 T9261 T9265 arg1Of expression,been
R7278 T9261 T9266 arg2Of expression,detected
R7279 T9144 T9142 arg3Of ],[
R7280 T9263 T9262 arg2Of DLBCL,in
R7281 T9145 T9126 arg1Of and,Moreover
R7282 T9266 T9264 arg2Of detected,has
R7283 T9266 T9265 arg2Of detected,been
R7284 T9266 T9271 arg1Of detected,[
R7285 T9145 T9127 arg1Of and,","
R7286 T9147 T9146 arg1Of levels,elevated
R7287 T9270 T9266 arg1Of profiling,detected
R7288 T9270 T9267 arg2Of profiling,by
R7289 T9270 T9268 arg1Of profiling,gene
R7290 T9270 T9269 arg1Of profiling,expression
R7291 T9272 T9271 arg2Of 12,[
R7292 T9273 T9271 arg3Of ],[
R7293 T9147 T9148 arg1Of levels,of
R7294 T9147 T9152 arg1Of levels,have
R7295 T9276 T9277 arg1Of production,of
R7296 T9276 T9280 arg1Of production,in
R7297 T9276 T9285 arg1Of production,was
R7298 T9276 T9286 arg2Of production,detected
R7299 T9147 T9153 arg1Of levels,been
R73 T198 T194 arg2Of cells,of
R7300 T9279 T9277 arg2Of transcripts,of
R7301 T9279 T9278 arg1Of transcripts,BMP-6
R7302 T9147 T9154 arg2Of levels,found
R7303 T9149 T9150 arg1Of Id1,and
R7304 T9284 T9280 arg2Of cells,in
R7305 T9284 T9281 arg1Of cells,normal
R7306 T9284 T9282 arg2Of cells,activated
R7307 T9284 T9283 arg1Of cells,B
R7308 T9150 T9148 arg2Of and,of
R7309 T9151 T9150 arg2Of Id3,and
R7310 T9154 T9145 arg2Of found,and
R7311 T9286 T9274 arg1Of detected,Furthermore
R7312 T9286 T9275 arg1Of detected,","
R7313 T9286 T9285 arg2Of detected,was
R7314 T9286 T9287 arg1Of detected,in
R7315 T9154 T9152 arg2Of found,have
R7316 T9290 T9287 arg2Of study,in
R7317 T9290 T9288 arg1Of study,the
R7318 T9290 T9289 arg1Of study,same
R7319 T9154 T9153 arg2Of found,been
R7320 T9292 T9291 arg2Of note,Of
R7321 T9154 T9155 arg1Of found,in
R7322 T9157 T9155 arg2Of synovia,in
R7323 T9297 T9294 arg1Of loop,an
R7324 T9297 T9295 arg1Of loop,autocrine
R7325 T9297 T9296 arg1Of loop,BMP-6
R7326 T9297 T9298 arg1Of loop,has
R7327 T9297 T9299 arg1Of loop,been
R7328 T9297 T9300 arg2Of loop,reported
R7329 T9157 T9156 arg1Of synovia,the
R7330 T9300 T9291 arg1Of reported,Of
R7331 T9300 T9293 arg1Of reported,","
R7332 T9300 T9298 arg2Of reported,has
R7333 T9300 T9299 arg2Of reported,been
R7334 T9300 T9301 arg1Of reported,by
R7335 T9300 T9306 arg1Of reported,in
R7336 T9300 T9309 arg1Of reported,[
R7337 T9301 T9305 arg1Of by,and
R7338 T9302 T9301 arg2Of others,by
R7339 T9302 T9303 arg1Of others,in
R7340 T9157 T9158 arg1Of synovia,of
R7341 T9304 T9303 arg2Of chondrocytes,in
R7342 T9157 T9160 arg1Of synovia,[
R7343 T9159 T9158 arg2Of RA-patients,of
R7344 T9306 T9305 arg2Of in,and
R7345 T9308 T9306 arg2Of ovarium,in
R7346 T9308 T9307 arg1Of ovarium,the
R7347 T9161 T9160 arg2Of 45,[
R7348 T9310 T9309 arg2Of "46,19,18",[
R7349 T9311 T9309 arg3Of ],[
R7350 T9162 T9160 arg3Of ],[
R7351 T9314 T9315 arg1Of we,wanted
R7352 T9314 T9317 arg1Of we,explore
R7353 T9315 T9312 arg1Of wanted,Therefore
R7354 T9315 T9313 arg1Of wanted,","
R7355 T9166 T9165 arg1Of results,these
R7356 T9317 T9315 arg2Of explore,wanted
R7357 T9317 T9316 arg1Of explore,to
R7358 T9317 T9320 arg1Of explore,for
R7359 T9319 T9317 arg2Of possibility,explore
R7360 T9319 T9318 arg1Of possibility,the
R7361 T9324 T9320 arg2Of loop,for
R7362 T9166 T9167 arg1Of results,point
R7363 T9167 T9163 arg1Of point,Altogether
R7364 T9324 T9321 arg1Of loop,an
R7365 T9324 T9322 arg1Of loop,autocrine
R7366 T9324 T9323 arg1Of loop,BMP-6
R7367 T9324 T9325 arg1Of loop,in
R7368 T9167 T9164 arg1Of point,","
R7369 T9167 T9168 arg1Of point,to
R7370 T9171 T9168 arg2Of role,to
R7371 T9328 T9325 arg2Of cells,in
R7372 T9328 T9326 arg1Of cells,human
R7373 T9328 T9327 arg1Of cells,B
R7374 T9329 T9330 arg1Of We,analysed
R7375 T9330 T9340 arg1Of analysed,by
R7376 T9330 T9364 arg1Of analysed,","
R7377 T9330 T9365 arg1Of analysed,anti-IgM
R7378 T9171 T9169 arg1Of role,an
R7379 T9334 T9330 arg2Of mRNA,analysed
R7380 T9334 T9331 arg1Of mRNA,the
R7381 T9334 T9332 arg1Of mRNA,expression
R7382 T9334 T9333 arg1Of mRNA,BMP-6
R7383 T9334 T9335 arg1Of mRNA,in
R7384 T9171 T9170 arg1Of role,important
R7385 T9171 T9172 arg1Of role,for
R7386 T9171 T9184 arg1Of role,in
R7387 T9339 T9335 arg2Of cells,in
R7388 T9339 T9336 arg1Of cells,peripheral
R7389 T9339 T9337 arg1Of cells,blood
R7390 T9339 T9338 arg1Of cells,B
R7391 T9172 T9183 arg1Of for,and
R7392 T9342 T9341 arg1Of PCR,real-time
R7393 T9342 T9344 arg1Of PCR,and
R7394 T9174 T9172 arg2Of proteins,for
R7395 T9344 T9340 arg2Of and,by
R7396 T9344 T9343 arg1Of and,","
R7397 T9345 T9344 arg2Of report,and
R7398 T9345 T9346 arg1Of report,here
R7399 T9174 T9173 arg1Of proteins,Id
R74 T198 T195 arg1Of cells,mature
R7400 T9348 T9340 arg3Of upregulation,by
R7401 T9348 T9347 arg1Of upregulation,the
R7402 T9348 T9349 arg1Of upregulation,of
R7403 T9348 T9353 arg1Of upregulation,after
R7404 T9348 T9355 arg1Of upregulation,with
R7405 T9174 T9175 arg1Of proteins,in
R7406 T9177 T9175 arg2Of regulation,in
R7407 T9352 T9349 arg2Of transcripts,of
R7408 T9352 T9350 arg1Of transcripts,endogenous
R7409 T9352 T9351 arg1Of transcripts,BMP-6
R7410 T9354 T9353 arg2Of stimulation,after
R7411 T9356 T9357 arg1Of FCS,","
R7412 T9357 T9355 arg2Of ",",with
R7413 T9357 T9360 arg1Of ",",and
R7414 T9357 T9361 arg1Of ",",","
R7415 T9357 T9363 arg1Of ",",importantly
R7416 T9359 T9357 arg2Of AB-serum,","
R7417 T9359 T9358 arg1Of AB-serum,human
R7418 T9177 T9176 arg1Of regulation,the
R7419 T9177 T9178 arg1Of regulation,of
R7420 T9182 T9178 arg2Of homeostasis,of
R7421 T9363 T9362 arg1Of importantly,most
R7422 T9369 T9368 arg1Of attempts,our
R7423 T9369 T9370 modOf attempts,to
R7424 T9369 T9375 arg1Of attempts,were
R7425 T9369 T9376 arg1Of attempts,unsuccessful
R7426 T9182 T9179 arg1Of homeostasis,normal
R7427 T9371 T9370 arg1Of study,to
R7428 T9182 T9180 arg1Of homeostasis,B
R7429 T9182 T9181 arg1Of homeostasis,cell
R7430 T9184 T9183 arg2Of in,and
R7431 T9374 T9371 arg2Of levels,study
R7432 T9374 T9372 arg1Of levels,BMP-6
R7433 T9374 T9373 arg1Of levels,protein
R7434 T9375 T9366 arg1Of were,However
R7435 T9375 T9367 arg1Of were,","
R7436 T9376 T9375 arg2Of unsuccessful,were
R7437 T9376 T9378 arg1Of unsuccessful,to
R7438 T9378 T9377 arg1Of to,due
R7439 T9379 T9378 arg2Of problems,to
R7440 T9379 T9380 arg1Of problems,with
R7441 T9185 T9184 arg2Of diseases,in
R7442 T9185 T9186 arg1Of diseases,","
R7443 T9382 T9381 arg1Of binding,unspecific
R7444 T9382 T9383 arg1Of binding,of
R7445 T9382 T9389 arg1Of binding,and
R7446 T9185 T9187 arg1Of diseases,where
R7447 T9481 T9466 arg1Of suggested,In
R7448 T9481 T9469 arg1Of suggested,","
R7449 T9481 T9480 arg2Of suggested,was
R7450 T9386 T9383 arg2Of antibodies,of
R7451 T9386 T9384 arg1Of antibodies,the
R7452 T9386 T9385 arg1Of antibodies,anti-BMP-6
R7453 T9386 T9387 arg2Of antibodies,tested
R7454 T9483 T9482 arg1Of upregulation,The
R7455 T9389 T9380 arg2Of and,with
R7456 T9389 T9388 arg1Of and,","
R7457 T9390 T9389 arg2Of lack,and
R7458 T9390 T9391 arg1Of lack,of
R7459 T9393 T9391 arg2Of staining,of
R7460 T9393 T9392 arg1Of staining,specific
R7461 T9393 T9394 arg1Of staining,in
R7462 T9483 T9484 arg1Of upregulation,of
R7463 T9396 T9394 arg2Of cells,in
R7464 T9396 T9395 arg1Of cells,control
R7465 T9396 T9397 arg2Of cells,known
R7466 T9483 T9487 arg1Of upregulation,after
R7467 T9396 T9399 arg1Of cells,express
R7468 T9483 T9489 arg1Of upregulation,is
R7469 T9483 T9490 arg1Of upregulation,of
R7470 T9486 T9484 arg2Of BMP-6-transcripts,of
R7471 T9399 T9397 arg3Of express,known
R7472 T9399 T9398 arg1Of express,to
R7473 T9401 T9399 arg2Of mRNA,express
R7474 T9401 T9400 arg1Of mRNA,BMP-6
R7475 T9486 T9485 arg1Of BMP-6-transcripts,the
R7476 T9403 T9402 arg2Of contrast,In
R7477 T9488 T9487 arg2Of IgM-crosslinking,after
R7478 T9489 T9493 arg1Of is,[
R7479 T9407 T9405 arg1Of protein,the
R7480 T9407 T9406 arg1Of protein,recombinant
R7481 T9407 T9408 arg1Of protein,was
R7482 T9407 T9410 arg2Of protein,detected
R7483 T9410 T9402 arg1Of detected,In
R7484 T9410 T9404 arg1Of detected,","
R7485 T9410 T9408 arg2Of detected,was
R7486 T9410 T9409 arg1Of detected,readily
R7487 T9490 T9489 arg2Of of,is
R7488 T9413 T9411 arg2Of respect,In
R7489 T9413 T9412 arg1Of respect,that
R7490 T9492 T9490 arg2Of interest,of
R7491 T9416 T9415 arg1Of investigators,few
R7492 T9416 T9417 arg1Of investigators,have
R7493 T9416 T9418 arg1Of investigators,detected
R7494 T9418 T9411 arg1Of detected,In
R7495 T9418 T9414 arg1Of detected,","
R7496 T9418 T9417 arg2Of detected,have
R7497 T9492 T9491 arg1Of interest,pathophysiologic
R7498 T9420 T9418 arg2Of protein,detected
R7499 T9420 T9419 arg1Of protein,BMP-6
R75 T198 T196 arg1Of cells,human
R7500 T9420 T9421 arg1Of protein,in
R7501 T9494 T9493 arg2Of 12,[
R7502 T9420 T9425 arg1Of protein,in
R7503 T9495 T9493 arg3Of ],[
R7504 T9421 T9423 arg1Of in,","
R7505 T9422 T9421 arg2Of humans,in
R7506 T9497 T9496 arg1Of loss,A
R7507 T9425 T9423 arg2Of in,","
R7508 T9425 T9424 arg1Of in,especially
R7509 T9427 T9425 arg2Of tissue,in
R7510 T9427 T9426 arg1Of tissue,non-pathogenic
R7511 T9429 T9428 arg1Of possibility,The
R7512 T9429 T9430 arg1Of possibility,of
R7513 T9429 T9436 arg1Of possibility,is
R7514 T9429 T9437 arg1Of possibility,in
R7515 T9497 T9498 arg1Of loss,of
R7516 T9432 T9430 arg2Of production,of
R7517 T9432 T9431 arg1Of production,BMP-6
R7518 T9432 T9433 arg1Of production,in
R7519 T9497 T9500 arg1Of loss,has
R7520 T9497 T9501 arg1Of loss,been
R7521 T9435 T9433 arg2Of B-cells,in
R7522 T9497 T9502 arg2Of loss,suggested
R7523 T9435 T9434 arg1Of B-cells,human
R7524 T9497 T9504 arg1Of loss,be
R7525 T9437 T9436 arg2Of in,is
R7526 T9438 T9437 arg2Of line,in
R7527 T9438 T9439 arg1Of line,with
R7528 T9499 T9498 arg2Of TGF-β-responsiveness,of
R7529 T9442 T9439 arg2Of work,with
R7530 T9442 T9440 arg1Of work,a
R7531 T9442 T9441 arg1Of work,recent
R7532 T9442 T9443 arg1Of work,that
R7533 T9442 T9444 arg1Of work,reported
R7534 T9502 T9500 arg2Of suggested,has
R7535 T9444 T9453 arg1Of reported,","
R7536 T9444 T9454 modOf reported,infiltrating
R7537 T9446 T9444 arg2Of production,reported
R7538 T9446 T9445 arg1Of production,the
R7539 T9446 T9447 arg1Of production,of
R7540 T9446 T9449 arg1Of production,in
R7541 T9448 T9447 arg2Of BMP-6,of
R7542 T9502 T9501 arg2Of suggested,been
R7543 T9502 T9511 arg1Of suggested,[
R7544 T9452 T9449 arg2Of cells,in
R7545 T9452 T9450 arg1Of cells,mouse
R7546 T9452 T9451 arg1Of cells,B
R7547 T9502 T9514 arg1Of suggested,and
R7548 T9504 T9502 arg3Of be,suggested
R7549 T9457 T9454 arg2Of marrow,infiltrating
R7550 T9457 T9455 arg1Of marrow,the
R7551 T9457 T9456 arg1Of marrow,bone
R7552 T9457 T9458 arg1Of marrow,of
R7553 T9504 T9503 arg1Of be,to
R7554 T9459 T9458 arg2Of mice,of
R7555 T9459 T9460 arg1Of mice,with
R7556 T9507 T9504 arg2Of contribution,be
R7557 T9462 T9460 arg2Of arthritis,with
R7558 T9462 T9461 arg1Of arthritis,inflammatory
R7559 T9462 T9463 arg1Of arthritis,[
R7560 T9464 T9463 arg2Of 43,[
R7561 T9465 T9463 arg3Of ],[
R7562 T9468 T9466 arg2Of study,In
R7563 T9468 T9467 arg1Of study,this
R7564 T9507 T9505 arg1Of contribution,a
R7565 T9507 T9506 arg1Of contribution,critical
R7566 T9471 T9470 arg1Of role,a
R7567 T9507 T9508 arg1Of contribution,to
R7568 T9510 T9508 arg2Of transformation,to
R7569 T9471 T9472 arg1Of role,for
R7570 T9471 T9480 arg1Of role,was
R7571 T9471 T9481 arg2Of role,suggested
R7572 T9510 T9509 arg1Of transformation,malignant
R7573 T9473 T9472 arg2Of BMPs,for
R7574 T9512 T9511 arg2Of "47,48",[
R7575 T9473 T9474 arg1Of BMPs,in
R7576 T9513 T9511 arg3Of ],[
R7577 T9477 T9474 arg2Of process,in
R7578 T9477 T9475 arg1Of process,the
R7579 T9477 T9476 arg1Of process,inflammatoric
R7580 T9477 T9478 arg1Of process,of
R7581 T9479 T9478 arg2Of arthritis,of
R7582 T9517 T9515 arg1Of mechanisms,similar
R7583 T9517 T9516 arg1Of mechanisms,oncogenic
R7584 T9517 T9518 arg1Of mechanisms,have
R7585 T9517 T9519 arg1Of mechanisms,been
R7586 T9577 T9576 arg1Of context,cellular
R7587 T9577 T9578 arg1Of context,of
R7588 T9577 T9583 arg1Of context,might
R7589 T9577 T9584 arg1Of context,define
R7590 T9517 T9520 arg2Of mechanisms,postulated
R7591 T9520 T9514 arg2Of postulated,and
R7592 T9582 T9578 arg2Of cell,of
R7593 T9582 T9579 arg1Of cell,the
R7594 T9582 T9580 arg1Of cell,BMP
R7595 T9582 T9581 arg1Of cell,target
R7596 T9584 T9574 arg2Of define,indicating
R7597 T9584 T9575 arg1Of define,that
R7598 T9584 T9583 arg2Of define,might
R7599 T9520 T9518 arg2Of postulated,have
R76 T198 T197 arg1Of cells,B
R7600 T9520 T9519 arg2Of postulated,been
R7601 T9520 T9521 arg1Of postulated,for
R7602 T9588 T9584 arg2Of effects,define
R7603 T9588 T9585 arg1Of effects,the
R7604 T9588 T9586 arg1Of effects,various
R7605 T9588 T9587 arg2Of effects,observed
R7606 T9589 T9591 arg1Of In,to
R7607 T9590 T9589 arg2Of contrast,In
R7608 T9522 T9521 arg2Of BMPs,for
R7609 T9593 T9589 arg3Of upregulation,In
R7610 T9593 T9592 arg1Of upregulation,the
R7611 T9593 T9594 arg1Of upregulation,of
R7612 T9596 T9594 arg2Of transcript,of
R7613 T9596 T9595 arg1Of transcript,BMP-6
R7614 T9596 T9597 arg1Of transcript,in
R7615 T9523 T9524 arg1Of Lines,of
R7616 T9599 T9597 arg2Of cells,in
R7617 T9599 T9598 arg1Of cells,B
R7618 T9523 T9526 arg1Of Lines,suggest
R7619 T9525 T9524 arg2Of evidence,of
R7620 T9601 T9602 arg1Of we,were
R7621 T9601 T9604 arg1Of we,able
R7622 T9601 T9606 arg1Of we,detect
R7623 T9526 T9527 arg1Of suggest,[
R7624 T9601 T9632 arg1Of we,consistent
R7625 T9602 T9589 arg1Of were,In
R7626 T9526 T9530 arg1Of suggest,that
R7627 T9602 T9600 arg1Of were,","
R7628 T9602 T9603 arg1Of were,not
R7629 T9602 T9631 arg1Of were,","
R7630 T9602 T9632 modOf were,consistent
R7631 T9602 T9648 arg1Of were,[
R7632 T9604 T9602 arg2Of able,were
R7633 T9528 T9527 arg2Of 49,[
R7634 T9606 T9604 arg2Of detect,able
R7635 T9606 T9605 arg1Of detect,to
R7636 T9608 T9606 arg2Of transcripts,detect
R7637 T9608 T9607 arg1Of transcripts,BMP-6
R7638 T9608 T9609 arg1Of transcripts,in
R7639 T9529 T9527 arg3Of ],[
R7640 T9533 T9531 arg2Of stages,at
R7641 T9613 T9614 arg1Of CD4+,or
R7642 T9615 T9614 arg2Of CD8+,or
R7643 T9617 T9609 arg2Of cells,in
R7644 T9617 T9610 arg1Of cells,human
R7645 T9617 T9611 arg1Of cells,peripheral
R7646 T9617 T9612 arg1Of cells,blood
R7647 T9617 T9613 arg1Of cells,CD4+
R7648 T9617 T9615 arg1Of cells,CD8+
R7649 T9617 T9616 arg1Of cells,T
R7650 T9617 T9618 arg1Of cells,(
R7651 T9619 T9620 arg1Of resting,or
R7652 T9533 T9532 arg1Of stages,early
R7653 T9533 T9534 arg1Of stages,of
R7654 T9621 T9620 arg2Of stimulated,or
R7655 T9621 T9622 arg1Of stimulated,with
R7656 T9621 T9626 arg1Of stimulated,;
R7657 T9623 T9624 arg1Of anti-CD3,and
R7658 T9624 T9622 arg2Of and,with
R7659 T9625 T9624 arg2Of anti-CD28,and
R7660 T9535 T9534 arg2Of carcinogenesis,of
R7661 T9627 T9618 arg2Of data,(
R7662 T9627 T9619 arg1Of data,resting
R7663 T9627 T9621 arg2Of data,stimulated
R7664 T9627 T9629 arg2Of data,shown
R7665 T9629 T9628 arg1Of shown,not
R7666 T9630 T9618 arg3Of ),(
R7667 T9537 T9538 arg1Of BMP-6,is
R7668 T9632 T9633 arg1Of consistent,with
R7669 T9537 T9545 arg1Of BMP-6,suppresses
R7670 T9635 T9633 arg2Of findings,with
R7671 T9635 T9634 arg1Of findings,the
R7672 T9635 T9636 arg1Of findings,in
R7673 T9635 T9646 arg1Of findings,in
R7674 T9538 T9539 arg1Of is,not
R7675 T9639 T9637 arg1Of lines,T
R7676 T9639 T9638 arg1Of lines,cell
R7677 T9639 T9640 arg1Of lines,[
R7678 T9639 T9643 arg1Of lines,and
R7679 T9538 T9544 arg1Of is,but
R7680 T9641 T9640 arg2Of 20,[
R7681 T9642 T9640 arg3Of ],[
R7682 T9542 T9538 arg2Of promoter,is
R7683 T9643 T9636 arg2Of and,in
R7684 T9645 T9643 arg2Of cells,and
R7685 T9645 T9644 arg1Of cells,T
R7686 T9647 T9646 arg2Of mice,in
R7687 T9649 T9648 arg2Of 43,[
R7688 T9542 T9540 arg1Of promoter,a
R7689 T9650 T9648 arg3Of ],[
R7690 T9542 T9541 arg1Of promoter,tumour
R7691 T9544 T9526 arg2Of but,suggest
R7692 T9654 T9651 arg1Of sources,Other
R7693 T9654 T9652 arg1Of sources,potential
R7694 T9654 T9653 arg1Of sources,BMP-6
R7695 T9654 T9655 arg1Of sources,for
R7696 T9654 T9661 arg1Of sources,might
R7697 T9654 T9662 arg1Of sources,be
R7698 T9544 T9531 arg1Of but,at
R7699 T9658 T9655 arg2Of cells,for
R77 T200 T192 arg3Of induction,inhibits
R7700 T9658 T9656 arg1Of cells,mature
R7701 T9658 T9657 arg1Of cells,B
R7702 T9658 T9660 arg1Of cells,vivo
R7703 T9544 T9536 arg1Of but,","
R7704 T9660 T9659 arg1Of vivo,in
R7705 T9544 T9543 arg1Of but,","
R7706 T9662 T9661 arg2Of be,might
R7707 T9662 T9671 arg1Of be,with
R7708 T9664 T9662 arg2Of cells,be
R7709 T9664 T9663 arg1Of cells,other
R7710 T9664 T9665 arg1Of cells,of
R7711 T9545 T9544 arg2Of suppresses,but
R7712 T9668 T9669 arg1Of system,or
R7713 T9669 T9665 arg2Of or,of
R7714 T9669 T9666 arg1Of or,the
R7715 T9669 T9667 arg1Of or,immune
R7716 T9546 T9547 arg1Of benign,and
R7717 T9670 T9669 arg2Of tissue,or
R7718 T9671 T9673 arg1Of with,to
R7719 T9672 T9671 arg2Of contact,with
R7720 T9548 T9547 arg2Of malignant,and
R7721 T9550 T9545 arg2Of outgrowth,suppresses
R7722 T9550 T9546 arg1Of outgrowth,benign
R7723 T9550 T9548 arg1Of outgrowth,malignant
R7724 T9550 T9549 arg1Of outgrowth,tumour
R7725 T9552 T9551 arg1Of findings,These
R7726 T9676 T9671 arg3Of system,with
R7727 T9676 T9674 arg1Of system,the
R7728 T9676 T9675 arg1Of system,hematopoietic
R7729 T9679 T9678 arg1Of recognized,well
R7730 T9680 T9677 arg1Of source,One
R7731 T9680 T9679 arg1Of source,recognized
R7732 T9680 T9681 arg1Of source,for
R7733 T9680 T9684 arg1Of source,is
R7734 T9552 T9553 arg1Of findings,are
R7735 T9552 T9554 arg1Of findings,in
R7736 T9683 T9681 arg2Of production,for
R7737 T9683 T9682 arg1Of production,BMP-6
R7738 T9553 T9573 arg1Of are,","
R7739 T9553 T9574 modOf are,indicating
R7740 T9684 T9692 arg1Of is,[
R7741 T9554 T9553 arg2Of in,are
R7742 T9556 T9554 arg2Of agreement,in
R7743 T9687 T9686 arg1Of bone,human
R7744 T9687 T9688 arg1Of bone,and
R7745 T9688 T9684 arg2Of and,is
R7746 T9688 T9685 arg1Of and,the
R7747 T9556 T9555 arg1Of agreement,good
R7748 T9691 T9688 arg2Of stroma,and
R7749 T9691 T9689 arg1Of stroma,bone
R7750 T9691 T9690 arg1Of stroma,marrow
R7751 T9556 T9557 arg1Of agreement,with
R7752 T9693 T9692 arg2Of "51,8",[
R7753 T9559 T9557 arg2Of findings,with
R7754 T9694 T9692 arg3Of ],[
R7755 T9559 T9558 arg1Of findings,previous
R7756 T9559 T9560 arg1Of findings,for
R7757 T9698 T9717 arg1Of is,and
R7758 T9699 T9698 arg2Of noteworthy,is
R7759 T9564 T9560 arg2Of members,for
R7760 T9705 T9701 arg1Of cells,human
R7761 T9705 T9702 arg1Of cells,umbilical
R7762 T9705 T9703 arg1Of cells,vein
R7763 T9705 T9704 arg1Of cells,endothelial
R7764 T9705 T9706 arg1Of cells,(
R7765 T9705 T9710 arg1Of cells,express
R7766 T9707 T9706 arg2Of HUVEC,(
R7767 T9708 T9706 arg3Of ),(
R7768 T9710 T9697 arg1Of express,it
R7769 T9710 T9698 arg1Of express,is
R7770 T9710 T9699 arg1Of express,noteworthy
R7771 T9710 T9700 arg1Of express,that
R7772 T9710 T9709 arg1Of express,highly
R7773 T9564 T9561 arg1Of members,other
R7774 T9712 T9710 arg2Of mRNA,express
R7775 T9564 T9562 arg1Of members,TGF-β
R7776 T9712 T9711 arg1Of mRNA,BMP-6
R7777 T9712 T9713 arg1Of mRNA,[
R7778 T9714 T9713 arg2Of 52,[
R7779 T9564 T9563 arg1Of members,family
R7780 T9715 T9713 arg3Of ],[
R7781 T9564 T9565 arg1Of members,","
R7782 T9564 T9566 arg1Of members,including
R7783 T9717 T9695 arg1Of and,Furthermore
R7784 T9717 T9696 arg1Of and,","
R7785 T9717 T9716 arg1Of and,","
R7786 T9567 T9568 arg1Of TGF-β1,and
R7787 T9719 T9718 arg1Of endothelium,vascular
R7788 T9719 T9720 arg1Of endothelium,has
R7789 T9719 T9721 arg1Of endothelium,been
R7790 T9719 T9722 arg2Of endothelium,reported
R7791 T9719 T9724 arg1Of endothelium,produce
R7792 T9722 T9717 arg2Of reported,and
R7793 T9722 T9720 arg2Of reported,has
R7794 T9722 T9721 arg2Of reported,been
R7795 T9724 T9722 arg3Of produce,reported
R7796 T9724 T9723 arg1Of produce,to
R7797 T9724 T9726 arg1Of produce,[
R7798 T9725 T9724 arg2Of BMP-6,produce
R7799 T9568 T9566 arg2Of and,including
R78 T200 T201 arg1Of induction,of
R7800 T9727 T9726 arg2Of 53,[
R7801 T9568 T9570 arg1Of and,[
R7802 T9728 T9726 arg3Of ],[
R7803 T9569 T9568 arg2Of BMP-4,and
R7804 T9730 T9729 arg1Of studies,These
R7805 T9730 T9731 arg1Of studies,might
R7806 T9730 T9732 arg1Of studies,imply
R7807 T9732 T9731 arg2Of imply,might
R7808 T9734 T9732 arg2Of role,imply
R7809 T9734 T9733 arg1Of role,a
R7810 T9734 T9735 arg1Of role,for
R7811 T9734 T9737 arg1Of role,in
R7812 T9571 T9570 arg2Of 50,[
R7813 T9736 T9735 arg2Of BMP-6,for
R7814 T9739 T9737 arg2Of migration,in
R7815 T9739 T9738 arg1Of migration,transendothelial
R7816 T9739 T9740 arg1Of migration,of
R7817 T9572 T9570 arg3Of ],[
R7818 T9772 T9773 arg1Of neutrophil,and
R7819 T9742 T9740 arg2Of cells,of
R7820 T9742 T9741 arg1Of cells,B
R7821 T9744 T9743 arg1Of mRNA,BMP-6
R7822 T9744 T9745 arg1Of mRNA,has
R7823 T9744 T9746 arg1Of mRNA,been
R7824 T9744 T9747 arg2Of mRNA,demonstrated
R7825 T9747 T9745 arg2Of demonstrated,has
R7826 T9747 T9746 arg2Of demonstrated,been
R7827 T9747 T9748 arg1Of demonstrated,in
R7828 T9747 T9756 arg1Of demonstrated,in
R7829 T9748 T9754 arg1Of in,but
R7830 T9752 T9748 arg2Of lines,in
R7831 T9752 T9749 arg1Of lines,murine
R7832 T9752 T9750 arg1Of lines,macrophage
R7833 T9752 T9751 arg1Of lines,cell
R7834 T9754 T9753 arg1Of but,","
R7835 T9773 T9771 arg2Of and,of
R7836 T9756 T9754 arg2Of in,but
R7837 T9756 T9755 arg1Of in,not
R7838 T9775 T9773 arg2Of origin,and
R7839 T9757 T9756 arg2Of humans,in
R7840 T9757 T9758 arg1Of humans,[
R7841 T9775 T9774 arg1Of origin,monocytic
R7842 T9778 T9761 arg1Of described,In
R7843 T9759 T9758 arg2Of 54,[
R7844 T9760 T9758 arg3Of ],[
R7845 T9761 T9763 arg1Of In,with
R7846 T9762 T9761 arg2Of accordance,In
R7847 T9778 T9766 arg1Of described,","
R7848 T9778 T9776 arg2Of described,have
R7849 T9765 T9761 arg3Of findings,In
R7850 T9778 T9777 arg2Of described,been
R7851 T9765 T9764 arg1Of findings,these
R7852 T9780 T9778 arg3Of be,described
R7853 T9780 T9779 arg1Of be,to
R7854 T9770 T9767 arg1Of lines,other
R7855 T9770 T9768 arg1Of lines,human
R7856 T9770 T9769 arg1Of lines,cell
R7857 T9770 T9771 arg1Of lines,of
R7858 T9770 T9776 arg1Of lines,have
R7859 T9770 T9777 arg1Of lines,been
R7860 T9770 T9778 arg2Of lines,described
R7861 T9770 T9780 arg1Of lines,be
R7862 T9770 T9781 arg1Of lines,negative
R7863 T9780 T9786 arg1Of be,[
R7864 T9781 T9780 arg2Of negative,be
R7865 T9781 T9782 arg1Of negative,for
R7866 T9785 T9782 arg2Of transcript,for
R7867 T9785 T9783 arg1Of transcript,the
R7868 T9785 T9784 arg1Of transcript,BMP-6
R7869 T9787 T9786 arg2Of 20,[
R7872 T9788 T9786 arg3Of ],[
R7873 T9791 T9789 arg2Of knowledge,To
R7878 T9791 T9790 arg1Of knowledge,our
R7880 T9793 T9794 arg1Of there,is
R7882 T9794 T9789 arg1Of is,To
R7885 T9794 T9792 arg1Of is,","
R7887 T9794 T9795 arg1Of is,currently
R7888 T9797 T9794 arg2Of report,is
R7891 T9797 T9796 arg1Of report,no
R7892 T9797 T9798 arg1Of report,about
R7893 T9800 T9798 arg2Of production,about
R7894 T9800 T9799 arg1Of production,BMP-6
R7895 T9800 T9801 arg1Of production,of
R7896 T9804 T9801 arg2Of cells,of
R7897 T9804 T9802 arg1Of cells,human
R7898 T9804 T9803 arg1Of cells,dendritic
R79 T203 T202 arg1Of phosphorylation,Smad
R80 T203 T204 arg1Of phosphorylation,and
R81 T204 T201 arg2Of and,of
R82 T205 T204 arg2Of upregulation,and
R83 T205 T206 arg1Of upregulation,of
R84 T207 T206 arg2Of Id1,of
R849 T1148 T1149 arg1Of Members,of
R85 T211 T209 arg1Of proteins,Bone
R850 T1148 T1159 arg1Of Members,play
R851 T1148 T1163 arg1Of Members,controlling
R852 T1154 T1152 arg1Of β,growth
R853 T1154 T1153 arg1Of β,factor
R854 T1154 T1155 arg1Of β,(
R855 T1156 T1155 arg2Of TGF-β,(
R856 T1157 T1155 arg3Of ),(
R857 T1158 T1149 arg2Of superfamily,of
R858 T1158 T1150 arg1Of superfamily,the
R859 T1158 T1151 arg1Of superfamily,transforming
R86 T211 T210 arg1Of proteins,morphogenetic
R860 T1158 T1154 arg1Of superfamily,β
R861 T1159 T1162 arg1Of play,in
R862 T1161 T1159 arg2Of roles,play
R863 T1161 T1160 arg1Of roles,central
R864 T1163 T1162 arg2Of controlling,in
R865 T1165 T1164 arg1Of proliferation,cellular
R866 T1165 T1166 arg1Of proliferation,","
R867 T1166 T1168 arg1Of ",",","
R868 T1167 T1166 arg2Of differentiation,","
R869 T1168 T1170 arg1Of ",",and
R87 T211 T212 arg1Of proteins,(
R870 T1169 T1168 arg2Of migration,","
R871 T1170 T1163 arg2Of and,controlling
R872 T1171 T1170 arg2Of apoptosis,and
R873 T1171 T1172 arg1Of apoptosis,[
R874 T1173 T1172 arg2Of 1,[
R875 T1174 T1172 arg3Of ],[
R876 T1176 T1175 arg1Of cytokines,These
R877 T1176 T1177 arg1Of cytokines,can
R878 T1176 T1178 arg1Of cytokines,be
R879 T1176 T1179 arg2Of cytokines,divided
R88 T211 T215 arg1Of proteins,belong
R880 T1179 T1177 arg2Of divided,can
R881 T1179 T1178 arg2Of divided,be
R882 T1179 T1180 arg1Of divided,into
R883 T1182 T1180 arg2Of subgroups,into
R884 T1182 T1181 arg1Of subgroups,three
R885 T1182 T1183 arg1Of subgroups,:
R886 T1184 T1185 arg1Of TGF-β,","
R887 T1184 T1189 arg1Of TGF-β,and
R888 T1187 T1185 arg2Of activins/inhibins,","
R889 T1187 T1186 arg1Of activins/inhibins,the
R89 T211 T221 arg1Of proteins,are
R890 T1189 T1183 arg2Of and,:
R891 T1189 T1188 arg1Of and,","
R892 T1193 T1189 arg2Of proteins,and
R893 T1193 T1190 arg1Of proteins,the
R894 T1193 T1191 arg1Of proteins,bone
R895 T1193 T1192 arg1Of proteins,morphogenetic
R896 T1193 T1194 arg1Of proteins,(
R897 T1193 T1197 arg1Of proteins,","
R898 T1193 T1198 arg2Of proteins,of
R899 T1193 T1199 arg1Of proteins,which
R90 T213 T212 arg2Of BMPs,(
R900 T1195 T1194 arg2Of BMPs,(
R901 T1196 T1194 arg3Of ),(
R902 T1201 T1200 arg1Of latter,the
R903 T1201 T1202 arg1Of latter,constitute
R904 T1202 T1198 arg1Of constitute,of
R905 T1205 T1202 arg2Of family,constitute
R906 T1205 T1203 arg1Of family,the
R907 T1205 T1204 arg1Of family,largest
R908 T1206 T1207 arg1Of BMPs,are
R909 T1208 T1209 arg1Of 30–38,kDa
R91 T214 T212 arg3Of ),(
R910 T1208 T1210 arg1Of 30–38,hetero-
R911 T1208 T1211 arg1Of 30–38,or
R912 T1212 T1211 arg2Of homodimeric,or
R913 T1213 T1207 arg2Of proteins,are
R914 T1213 T1208 arg1Of proteins,30–38
R915 T1213 T1212 arg1Of proteins,homodimeric
R916 T1213 T1215 arg2Of proteins,identified
R917 T1215 T1214 arg1Of identified,originally
R918 T1218 T1215 arg1Of ability,identified
R919 T1218 T1216 arg2Of ability,by
R92 T215 T216 arg1Of belong,to
R920 T1218 T1217 arg1Of ability,their
R921 T1218 T1219 modOf ability,to
R922 T1220 T1219 arg1Of induce,to
R923 T1220 T1226 arg1Of induce,[
R924 T1222 T1221 arg1Of cartilage,ectopic
R925 T1222 T1223 arg1Of cartilage,and
R926 T1223 T1220 arg2Of and,induce
R927 T1225 T1223 arg2Of formation,and
R928 T1225 T1224 arg1Of formation,bone
R929 T1227 T1226 arg2Of "2,3",[
R93 T215 T220 arg1Of belong,and
R930 T1228 T1226 arg3Of ],[
R931 T1230 T1229 arg1Of studies,Several
R932 T1230 T1231 arg1Of studies,have
R933 T1230 T1232 arg1Of studies,demonstrated
R934 T1232 T1231 arg2Of demonstrated,have
R935 T1232 T1244 arg1Of demonstrated,recently
R936 T1232 T1245 arg1Of demonstrated,","
R937 T1232 T1247 arg1Of demonstrated,in
R938 T1235 T1232 arg2Of role,demonstrated
R939 T1235 T1233 arg1Of role,an
R94 T219 T216 arg2Of superfamily,to
R940 T1235 T1234 arg1Of role,essential
R941 T1235 T1236 arg1Of role,of
R942 T1235 T1239 arg1Of role,during
R943 T1235 T1242 arg1Of role,and
R944 T1238 T1236 arg2Of proteins,of
R945 T1238 T1237 arg1Of proteins,these
R946 T1240 T1239 arg2Of embryogenesis,during
R947 T1242 T1241 arg1Of and,","
R948 T1244 T1243 arg1Of recently,more
R949 T1247 T1246 arg1Of in,also
R95 T219 T217 arg1Of superfamily,the
R950 T1249 T1247 arg2Of tissues,in
R951 T1249 T1248 arg1Of tissues,adult
R952 T1249 T1250 arg1Of tissues,[
R953 T1251 T1250 arg2Of 1,[
R954 T1252 T1250 arg3Of ],[
R955 T1253 T1254 arg1Of TGF-β,has
R956 T1253 T1255 arg1Of TGF-β,been
R957 T1253 T1257 arg2Of TGF-β,studied
R958 T1253 T1265 arg1Of TGF-β,is
R959 T1257 T1254 arg2Of studied,has
R96 T219 T218 arg1Of superfamily,TGF-β
R960 T1257 T1255 arg2Of studied,been
R961 T1257 T1256 arg1Of studied,intensively
R962 T1257 T1258 arg1Of studied,in
R963 T1257 T1264 arg1Of studied,and
R964 T1259 T1260 arg1Of normal,and
R965 T1261 T1260 arg2Of malignant,and
R966 T1263 T1258 arg2Of cells,in
R967 T1263 T1259 arg1Of cells,normal
R968 T1263 T1261 arg1Of cells,malignant
R969 T1263 T1262 arg1Of cells,haematopoietic
R97 T221 T220 arg2Of are,and
R970 T1265 T1264 arg2Of is,and
R971 T1266 T1265 arg2Of one,is
R972 T1266 T1267 arg1Of one,of
R973 T1271 T1269 arg1Of endogenous,most
R974 T1271 T1270 arg1Of endogenous,potent
R975 T1273 T1267 arg2Of regulators,of
R976 T1273 T1268 arg1Of regulators,the
R977 T1273 T1271 arg1Of regulators,endogenous
R978 T1273 T1272 arg1Of regulators,negative
R979 T1273 T1274 arg2Of regulators,known
R98 T221 T227 arg1Of are,in
R980 T1274 T1275 arg1Of known,to
R981 T1276 T1275 arg2Of date.,to
R982 T1276 T1277 arg1Of date.,[
R983 T1278 T1277 arg2Of 4,[
R984 T1279 T1277 arg3Of ],[
R985 T1281 T1280 arg2Of contrast,In
R986 T1284 T1283 arg1Of effect,the
R987 T1284 T1285 arg1Of effect,of
R988 T1284 T1287 arg1Of effect,in
R989 T1284 T1291 arg1Of effect,has
R99 T223 T221 arg2Of proteins,are
R990 T1284 T1293 arg1Of effect,been
R991 T1284 T1295 arg2Of effect,investigated
R992 T1286 T1285 arg2Of BMPs,of
R993 T1290 T1287 arg2Of system,in
R994 T1290 T1288 arg1Of system,the
R995 T1290 T1289 arg1Of system,immune
R996 T1295 T1280 arg1Of investigated,In
R997 T1295 T1282 arg1Of investigated,","
R998 T1295 T1291 arg2Of investigated,has
R999 T1295 T1292 arg1Of investigated,not