Id |
Subject |
Object |
Predicate |
Lexical cue |
T14971 |
0-10 |
NN |
denotes |
Activation |
T14972 |
11-13 |
IN |
denotes |
of |
T14973 |
14-22 |
NN |
denotes |
PI3K/Akt |
T14974 |
23-29 |
NN |
denotes |
signal |
T14975 |
30-42 |
NN |
denotes |
transduction |
T14976 |
43-50 |
NN |
denotes |
pathway |
T14977 |
51-53 |
IN |
denotes |
on |
T14978 |
54-59 |
NN |
denotes |
IL-17 |
T14979 |
60-70 |
NN |
denotes |
production |
T14980 |
71-73 |
IN |
denotes |
by |
T14981 |
74-82 |
JJ |
denotes |
anti-CD3 |
T14982 |
83-85 |
TO |
denotes |
To |
T14983 |
86-95 |
VB |
denotes |
determine |
T14984 |
96-106 |
JJ |
denotes |
downstream |
T14985 |
107-115 |
NN |
denotes |
effector |
T14986 |
116-125 |
NN |
denotes |
molecules |
T14987 |
126-128 |
IN |
denotes |
of |
T14988 |
129-132 |
DT |
denotes |
the |
T14989 |
133-137 |
NN |
denotes |
PI3K |
T14990 |
138-145 |
NN |
denotes |
pathway |
T14991 |
145-146 |
-COMMA- |
denotes |
, |
T14992 |
147-149 |
PRP |
denotes |
we |
T14993 |
150-159 |
VB |
denotes |
evaluated |
T14994 |
160-163 |
DT |
denotes |
the |
T14995 |
164-174 |
NN |
denotes |
activation |
T14996 |
175-177 |
IN |
denotes |
of |
T14997 |
178-181 |
NN |
denotes |
Akt |
T14998 |
182-184 |
IN |
denotes |
by |
T14999 |
185-192 |
JJ |
denotes |
western |
T15000 |
193-201 |
NN |
denotes |
blotting |
T15001 |
203-205 |
IN |
denotes |
As |
T15002 |
206-211 |
VB |
denotes |
shown |
T15003 |
212-214 |
IN |
denotes |
in |
T15004 |
215-219 |
NNP |
denotes |
Fig. |
T15005 |
220-221 |
CD |
denotes |
6 |
T15006 |
221-222 |
-COMMA- |
denotes |
, |
T15007 |
223-225 |
IN |
denotes |
at |
T15008 |
226-228 |
CD |
denotes |
10 |
T15009 |
229-232 |
NN |
denotes |
min |
T15010 |
233-235 |
IN |
denotes |
of |
T15011 |
236-246 |
NN |
denotes |
incubation |
T15012 |
247-251 |
IN |
denotes |
with |
T15013 |
252-260 |
NN |
denotes |
anti-CD3 |
T15014 |
261-262 |
-LRB- |
denotes |
( |
T15015 |
262-264 |
CD |
denotes |
10 |
T15016 |
265-270 |
NN |
denotes |
μg/ml |
T15017 |
270-271 |
-RRB- |
denotes |
) |
T15018 |
272-274 |
CC |
denotes |
or |
T15019 |
275-283 |
NN |
denotes |
LY294002 |
T15020 |
284-285 |
-LRB- |
denotes |
( |
T15021 |
285-287 |
CD |
denotes |
20 |
T15022 |
288-290 |
NN |
denotes |
μM |
T15023 |
290-291 |
-RRB- |
denotes |
) |
T15024 |
291-292 |
-COMMA- |
denotes |
, |
T15025 |
293-295 |
DT |
denotes |
no |
T15026 |
296-306 |
NN |
denotes |
difference |
T15027 |
307-309 |
IN |
denotes |
in |
T15028 |
310-313 |
DT |
denotes |
the |
T15029 |
314-321 |
NN |
denotes |
amounts |
T15030 |
322-324 |
IN |
denotes |
of |
T15031 |
325-339 |
VB |
denotes |
phosphorylated |
T15032 |
340-343 |
NN |
denotes |
Akt |
T15033 |
344-347 |
VB |
denotes |
was |
T15034 |
348-356 |
VB |
denotes |
observed |
T15035 |
358-365 |
RB |
denotes |
However |
T15036 |
365-366 |
-COMMA- |
denotes |
, |
T15037 |
367-372 |
IN |
denotes |
after |
T15038 |
373-375 |
CD |
denotes |
30 |
T15039 |
376-379 |
NN |
denotes |
min |
T15040 |
380-382 |
IN |
denotes |
of |
T15041 |
383-393 |
NN |
denotes |
incubation |
T15042 |
393-394 |
-COMMA- |
denotes |
, |
T15043 |
395-409 |
VB |
denotes |
phosphorylated |
T15044 |
410-413 |
NN |
denotes |
Akt |
T15045 |
414-423 |
VB |
denotes |
increased |
T15046 |
424-425 |
-LRB- |
denotes |
( |
T15047 |
425-429 |
NN |
denotes |
lane |
T15048 |
430-431 |
CD |
denotes |
2 |
T15049 |
431-432 |
-RRB- |
denotes |
) |
T15050 |
432-433 |
-COMMA- |
denotes |
, |
T15051 |
434-437 |
CC |
denotes |
and |
T15052 |
438-441 |
DT |
denotes |
the |
T15053 |
442-448 |
NN |
denotes |
effect |
T15054 |
449-451 |
IN |
denotes |
of |
T15055 |
452-462 |
NN |
denotes |
inhibition |
T15056 |
463-465 |
IN |
denotes |
by |
T15057 |
466-474 |
NN |
denotes |
LY294002 |
T15058 |
475-476 |
-LRB- |
denotes |
( |
T15059 |
476-480 |
NN |
denotes |
lane |
T15060 |
481-482 |
CD |
denotes |
3 |
T15061 |
482-483 |
-RRB- |
denotes |
) |
T15062 |
484-491 |
VB |
denotes |
reached |
T15063 |
492-493 |
DT |
denotes |
a |
T15064 |
494-498 |
NN |
denotes |
peak |
T15065 |
499-501 |
IN |
denotes |
at |
T15066 |
502-504 |
CD |
denotes |
60 |
T15067 |
505-508 |
NN |
denotes |
min |
T15068 |
508-509 |
-COMMA- |
denotes |
, |
T15069 |
510-517 |
VB |
denotes |
lasting |
T15070 |
518-520 |
TO |
denotes |
to |
T15071 |
521-528 |
CD |
denotes |
120–240 |
T15072 |
529-532 |
NN |
denotes |
min |
T15073 |
534-536 |
IN |
denotes |
In |
T15074 |
537-545 |
NN |
denotes |
contrast |
T15075 |
545-546 |
-COMMA- |
denotes |
, |
T15076 |
547-565 |
JJ |
denotes |
non-phosphorylated |
T15077 |
566-569 |
NN |
denotes |
Akt |
T15078 |
570-573 |
CC |
denotes |
and |
T15079 |
574-581 |
NN |
denotes |
β-actin |
T15080 |
582-590 |
VB |
denotes |
remained |
T15081 |
591-600 |
JJ |
denotes |
unchanged |
T15082 |
601-611 |
RB |
denotes |
regardless |
T15083 |
612-614 |
IN |
denotes |
of |
T15084 |
615-625 |
NN |
denotes |
incubation |
T15085 |
626-630 |
NN |
denotes |
time |
T15086 |
632-635 |
NN |
denotes |
PHA |
T15087 |
635-636 |
-COMMA- |
denotes |
, |
T15088 |
637-649 |
NN |
denotes |
concanavalin |
T15089 |
650-651 |
NN |
denotes |
A |
T15090 |
652-655 |
CC |
denotes |
and |
T15091 |
656-661 |
NN |
denotes |
IL-15 |
T15092 |
662-666 |
RB |
denotes |
also |
T15093 |
667-679 |
VB |
denotes |
demonstrated |
T15094 |
680-683 |
DT |
denotes |
the |
T15095 |
684-688 |
JJ |
denotes |
same |
T15096 |
689-695 |
NN |
denotes |
effect |
T15097 |
696-698 |
IN |
denotes |
on |
T15098 |
699-713 |
VB |
denotes |
phosphorylated |
T15099 |
714-717 |
NN |
denotes |
Akt |
T15100 |
718-720 |
IN |
denotes |
as |
T15101 |
721-726 |
VB |
denotes |
shown |
T15102 |
727-731 |
IN |
denotes |
with |
T15103 |
732-740 |
NN |
denotes |
anti-CD3 |
T15104 |
740-741 |
-COMMA- |
denotes |
, |
T15105 |
742-747 |
WDT |
denotes |
which |
T15106 |
748-751 |
VB |
denotes |
was |
T15107 |
752-754 |
DT |
denotes |
an |
T15108 |
755-765 |
NN |
denotes |
inhibition |
T15109 |
766-768 |
IN |
denotes |
by |
T15110 |
769-779 |
NN |
denotes |
wortmannin |
T15111 |
780-783 |
CC |
denotes |
and |
T15112 |
784-788 |
NN |
denotes |
PDTC |
T15113 |
789-791 |
RB |
denotes |
as |
T15114 |
792-796 |
RB |
denotes |
well |
T15115 |
797-799 |
IN |
denotes |
as |
T15116 |
800-802 |
IN |
denotes |
by |
T15117 |
803-811 |
NN |
denotes |
LY294002 |
T15118 |
812-813 |
-LRB- |
denotes |
( |
T15119 |
813-817 |
NN |
denotes |
data |
T15120 |
818-821 |
RB |
denotes |
not |
T15121 |
822-827 |
VB |
denotes |
shown |
T15122 |
827-828 |
-RRB- |
denotes |
) |
R8171 |
T14971 |
T14972 |
arg1Of |
Activation,of |
R8172 |
T14971 |
T14977 |
arg1Of |
Activation,on |
R8173 |
T14971 |
T14980 |
arg1Of |
Activation,by |
R8174 |
T14976 |
T14972 |
arg2Of |
pathway,of |
R8175 |
T14976 |
T14973 |
arg1Of |
pathway,PI3K/Akt |
R8176 |
T14976 |
T14974 |
arg1Of |
pathway,signal |
R8177 |
T14976 |
T14975 |
arg1Of |
pathway,transduction |
R8178 |
T14979 |
T14977 |
arg2Of |
production,on |
R8179 |
T14979 |
T14978 |
arg1Of |
production,IL-17 |
R8180 |
T14981 |
T14980 |
arg2Of |
anti-CD3,by |
R8181 |
T14983 |
T14982 |
arg1Of |
determine,To |
R8182 |
T14986 |
T14983 |
arg2Of |
molecules,determine |
R8183 |
T14986 |
T14984 |
arg1Of |
molecules,downstream |
R8184 |
T14986 |
T14985 |
arg1Of |
molecules,effector |
R8185 |
T14986 |
T14987 |
arg1Of |
molecules,of |
R8186 |
T14990 |
T14987 |
arg2Of |
pathway,of |
R8187 |
T14990 |
T14988 |
arg1Of |
pathway,the |
R8188 |
T14990 |
T14989 |
arg1Of |
pathway,PI3K |
R8189 |
T14992 |
T14983 |
arg1Of |
we,determine |
R8190 |
T14992 |
T14993 |
arg1Of |
we,evaluated |
R8191 |
T14993 |
T14982 |
modOf |
evaluated,To |
R8192 |
T14993 |
T14991 |
arg1Of |
evaluated,"," |
R8193 |
T14995 |
T14993 |
arg2Of |
activation,evaluated |
R8194 |
T14995 |
T14994 |
arg1Of |
activation,the |
R8195 |
T14995 |
T14996 |
arg1Of |
activation,of |
R8196 |
T14995 |
T14998 |
arg1Of |
activation,by |
R8197 |
T14997 |
T14996 |
arg2Of |
Akt,of |
R8198 |
T15000 |
T14998 |
arg2Of |
blotting,by |
R8199 |
T15000 |
T14999 |
arg1Of |
blotting,western |
R8200 |
T15002 |
T15001 |
arg2Of |
shown,As |
R8201 |
T15002 |
T15003 |
arg1Of |
shown,in |
R8202 |
T15002 |
T15006 |
arg1Of |
shown,"," |
R8203 |
T15002 |
T15007 |
arg1Of |
shown,at |
R8204 |
T15004 |
T15003 |
arg2Of |
Fig.,in |
R8205 |
T15004 |
T15005 |
arg1Of |
Fig.,6 |
R8206 |
T15009 |
T15007 |
arg2Of |
min,at |
R8207 |
T15009 |
T15008 |
arg1Of |
min,10 |
R8208 |
T15009 |
T15010 |
arg1Of |
min,of |
R8209 |
T15009 |
T15012 |
arg1Of |
min,with |
R8210 |
T15011 |
T15010 |
arg2Of |
incubation,of |
R8211 |
T15013 |
T15014 |
arg1Of |
anti-CD3,( |
R8212 |
T15013 |
T15018 |
arg1Of |
anti-CD3,or |
R8213 |
T15016 |
T15014 |
arg2Of |
μg/ml,( |
R8214 |
T15016 |
T15015 |
arg1Of |
μg/ml,10 |
R8215 |
T15017 |
T15014 |
arg3Of |
),( |
R8216 |
T15018 |
T15012 |
arg2Of |
or,with |
R8217 |
T15019 |
T15018 |
arg2Of |
LY294002,or |
R8218 |
T15019 |
T15020 |
arg1Of |
LY294002,( |
R8219 |
T15022 |
T15020 |
arg2Of |
μM,( |
R8220 |
T15022 |
T15021 |
arg1Of |
μM,20 |
R8221 |
T15023 |
T15020 |
arg3Of |
),( |
R8222 |
T15026 |
T15025 |
arg1Of |
difference,no |
R8223 |
T15026 |
T15027 |
arg1Of |
difference,in |
R8224 |
T15026 |
T15033 |
arg1Of |
difference,was |
R8225 |
T15026 |
T15034 |
arg2Of |
difference,observed |
R8226 |
T15029 |
T15027 |
arg2Of |
amounts,in |
R8227 |
T15029 |
T15028 |
arg1Of |
amounts,the |
R8228 |
T15029 |
T15030 |
arg1Of |
amounts,of |
R8229 |
T15032 |
T15030 |
arg2Of |
Akt,of |
R8230 |
T15032 |
T15031 |
arg2Of |
Akt,phosphorylated |
R8231 |
T15034 |
T15001 |
arg1Of |
observed,As |
R8232 |
T15034 |
T15024 |
arg1Of |
observed,"," |
R8233 |
T15034 |
T15033 |
arg2Of |
observed,was |
R8234 |
T15039 |
T15037 |
arg2Of |
min,after |
R8235 |
T15039 |
T15038 |
arg1Of |
min,30 |
R8236 |
T15039 |
T15040 |
arg1Of |
min,of |
R8237 |
T15041 |
T15040 |
arg2Of |
incubation,of |
R8238 |
T15044 |
T15043 |
arg2Of |
Akt,phosphorylated |
R8239 |
T15044 |
T15045 |
arg1Of |
Akt,increased |
R8240 |
T15045 |
T15046 |
arg1Of |
increased,( |
R8241 |
T15045 |
T15051 |
arg1Of |
increased,and |
R8242 |
T15047 |
T15046 |
arg2Of |
lane,( |
R8243 |
T15047 |
T15048 |
arg1Of |
lane,2 |
R8244 |
T15049 |
T15046 |
arg3Of |
),( |
R8245 |
T15051 |
T15035 |
arg1Of |
and,However |
R8246 |
T15051 |
T15036 |
arg1Of |
and,"," |
R8247 |
T15051 |
T15037 |
arg1Of |
and,after |
R8248 |
T15051 |
T15042 |
arg1Of |
and,"," |
R8249 |
T15051 |
T15050 |
arg1Of |
and,"," |
R8250 |
T15053 |
T15052 |
arg1Of |
effect,the |
R8251 |
T15053 |
T15054 |
arg1Of |
effect,of |
R8252 |
T15053 |
T15056 |
arg1Of |
effect,by |
R8253 |
T15053 |
T15062 |
arg1Of |
effect,reached |
R8254 |
T15053 |
T15069 |
arg1Of |
effect,lasting |
R8255 |
T15055 |
T15054 |
arg2Of |
inhibition,of |
R8256 |
T15057 |
T15056 |
arg2Of |
LY294002,by |
R8257 |
T15057 |
T15058 |
arg1Of |
LY294002,( |
R8258 |
T15059 |
T15058 |
arg2Of |
lane,( |
R8259 |
T15059 |
T15060 |
arg1Of |
lane,3 |
R8260 |
T15061 |
T15058 |
arg3Of |
),( |
R8261 |
T15062 |
T15051 |
arg2Of |
reached,and |
R8262 |
T15062 |
T15065 |
arg1Of |
reached,at |
R8263 |
T15062 |
T15068 |
arg1Of |
reached,"," |
R8264 |
T15062 |
T15069 |
modOf |
reached,lasting |
R8265 |
T15064 |
T15062 |
arg2Of |
peak,reached |
R8266 |
T15064 |
T15063 |
arg1Of |
peak,a |
R8267 |
T15067 |
T15065 |
arg2Of |
min,at |
R8268 |
T15067 |
T15066 |
arg1Of |
min,60 |
R8269 |
T15069 |
T15070 |
arg1Of |
lasting,to |
R8270 |
T15072 |
T15070 |
arg2Of |
min,to |
R8271 |
T15072 |
T15071 |
arg1Of |
min,120–240 |
R8272 |
T15074 |
T15073 |
arg2Of |
contrast,In |
R8273 |
T15077 |
T15078 |
arg1Of |
Akt,and |
R8274 |
T15078 |
T15076 |
arg1Of |
and,non-phosphorylated |
R8275 |
T15078 |
T15080 |
arg1Of |
and,remained |
R8276 |
T15078 |
T15081 |
arg1Of |
and,unchanged |
R8277 |
T15079 |
T15078 |
arg2Of |
β-actin,and |
R8278 |
T15080 |
T15073 |
arg1Of |
remained,In |
R8279 |
T15080 |
T15075 |
arg1Of |
remained,"," |
R8280 |
T15080 |
T15082 |
arg1Of |
remained,regardless |
R8281 |
T15081 |
T15080 |
arg2Of |
unchanged,remained |
R8282 |
T15082 |
T15083 |
arg1Of |
regardless,of |
R8283 |
T15085 |
T15083 |
arg2Of |
time,of |
R8284 |
T15085 |
T15084 |
arg1Of |
time,incubation |
R8285 |
T15086 |
T15087 |
arg1Of |
PHA,"," |
R8286 |
T15087 |
T15090 |
arg1Of |
",",and |
R8287 |
T15089 |
T15087 |
arg2Of |
A,"," |
R8288 |
T15089 |
T15088 |
arg1Of |
A,concanavalin |
R8289 |
T15090 |
T15093 |
arg1Of |
and,demonstrated |
R8290 |
T15091 |
T15090 |
arg2Of |
IL-15,and |
R8291 |
T15093 |
T15092 |
arg1Of |
demonstrated,also |
R8292 |
T15093 |
T15097 |
arg1Of |
demonstrated,on |
R8293 |
T15093 |
T15100 |
arg1Of |
demonstrated,as |
R8294 |
T15093 |
T15104 |
arg1Of |
demonstrated,"," |
R8295 |
T15093 |
T15105 |
arg1Of |
demonstrated,which |
R8296 |
T15093 |
T15106 |
arg1Of |
demonstrated,was |
R8297 |
T15096 |
T15093 |
arg2Of |
effect,demonstrated |
R8298 |
T15096 |
T15094 |
arg1Of |
effect,the |
R8299 |
T15096 |
T15095 |
arg1Of |
effect,same |
R8300 |
T15099 |
T15097 |
arg2Of |
Akt,on |
R8301 |
T15099 |
T15098 |
arg2Of |
Akt,phosphorylated |
R8302 |
T15101 |
T15100 |
arg2Of |
shown,as |
R8303 |
T15101 |
T15102 |
arg1Of |
shown,with |
R8304 |
T15103 |
T15102 |
arg2Of |
anti-CD3,with |
R8305 |
T15106 |
T15109 |
arg1Of |
was,by |
R8306 |
T15106 |
T15116 |
arg1Of |
was,by |
R8307 |
T15108 |
T15106 |
arg2Of |
inhibition,was |
R8308 |
T15108 |
T15107 |
arg1Of |
inhibition,an |
R8309 |
T15109 |
T15115 |
arg1Of |
by,as |
R8310 |
T15110 |
T15111 |
arg1Of |
wortmannin,and |
R8311 |
T15111 |
T15109 |
arg2Of |
and,by |
R8312 |
T15112 |
T15111 |
arg2Of |
PDTC,and |
R8313 |
T15115 |
T15113 |
arg1Of |
as,as |
R8314 |
T15115 |
T15114 |
arg1Of |
as,well |
R8315 |
T15116 |
T15115 |
arg2Of |
by,as |
R8316 |
T15117 |
T15116 |
arg2Of |
LY294002,by |
R8317 |
T15117 |
T15118 |
arg1Of |
LY294002,( |
R8318 |
T15119 |
T15118 |
arg2Of |
data,( |
R8319 |
T15119 |
T15121 |
arg2Of |
data,shown |
R8320 |
T15121 |
T15120 |
arg1Of |
shown,not |
R8321 |
T15122 |
T15118 |
arg3Of |
),( |