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PMC:3245220 JSONTXT 23 Projects

Annnotations TAB TSV DIC JSON TextAE-old TextAE

Id Subject Object Predicate Lexical cue Negation Speculation
T695 0-5 Protein denotes M-CSF
T696 6-13 Positive_regulation denotes Induces
T697 35-45 Positive_regulation denotes Activating
T698 52-55 Protein denotes p65
T699 56-71 Phosphorylation denotes Phosphorylation
T700 75-81 Entity denotes Ser276
T701 134-170 Protein denotes Macrophage colony-stimulating factor
T702 172-177 Protein denotes M-CSF
T703 333-338 Protein denotes M-CSF
T704 493-498 Protein denotes M-CSF
T705 707-711 Protein denotes PKCα
T706 712-713 Protein denotes β
T707 714-723 Negative_regulation denotes inhibitor
T708 714-723 Negative_regulation denotes inhibitor
T709 733-747 Gene_expression denotes overexpression
T710 751-773 Protein denotes dominant negative PKCα
T711 789-799 Protein denotes PKCα siRNA
T712 838-843 Protein denotes M-CSF
T713 871-878 Negative_regulation denotes reduced
T714 879-885 Entity denotes Ser276
T715 886-901 Phosphorylation denotes phosphorylation
T716 910-913 Protein denotes p65
T717 935-940 Protein denotes M-CSF
T718 1025-1029 Protein denotes PKCα
T719 1033-1042 Regulation denotes important
T720 1064-1069 Protein denotes M-CSF
T721 1070-1077 Positive_regulation denotes induced
T722 1151-1154 Protein denotes p65
T723 1155-1161 Entity denotes Ser276
T724 1162-1177 Phosphorylation denotes phosphorylation
T725 1231-1234 Protein denotes p65
T726 1235-1241 Entity denotes Ser276
T727 1279-1284 Protein denotes M-CSF
T4262 1509-1545 Protein denotes Macrophage colony-stimulating factor
T4263 1547-1552 Protein denotes M-CSF
T4264 1634-1639 Protein denotes M-CSF
T4265 1890-1895 Protein denotes M-CSF
T4266 2213-2217 Protein denotes RelA
T4267 2218-2221 Protein denotes p65
T4268 2223-2226 Protein denotes p50
T4269 2228-2231 Protein denotes p52
T4270 2233-2238 Protein denotes c-Rel
T4271 2243-2247 Protein denotes RelB
T4272 2291-2294 Protein denotes p50
T4273 2295-2298 Protein denotes p65
T4274 2357-2360 Protein denotes p65
T4275 2376-2379 Protein denotes p65
T4276 2440-2447 Negative_regulation denotes lacking
T4277 2454-2457 Protein denotes p65
T4278 2564-2567 Protein denotes p65
T4279 2568-2572 Negative_regulation denotes null
T4280 2597-2601 Protein denotes TNFα
T4281 2640-2654 Gene_expression denotes overexpressing
T4282 2665-2668 Protein denotes p65
T4283 3331-3334 Protein denotes p50
T4284 3335-3338 Protein denotes p65
T4285 3380-3384 Protein denotes IκBα
T4286 3391-3395 Positive_regulation denotes Upon
T4287 3391-3395 Positive_regulation denotes Upon
T4288 3438-3442 Protein denotes IκBα
T4289 3446-3460 Phosphorylation denotes phosphorylated
T4290 3481-3489 Protein_catabolism denotes degraded
T4291 3507-3510 Protein denotes p50
T4292 3511-3514 Protein denotes p65
T4293 3587-3594 Localization denotes release
T4294 3600-3604 Protein denotes IκBα
T4295 3612-3615 Protein denotes p65
T4296 3628-3659 Protein_modification denotes post-translational modification
T4297 3710-3713 Protein denotes p65
T4298 3714-3729 Phosphorylation denotes phosphorylation
T4299 3853-3868 Phosphorylation denotes phosphorylation
T4300 3853-3868 Phosphorylation denotes phosphorylation
T4301 3853-3868 Phosphorylation denotes phosphorylation
T4302 3878-3881 Protein denotes p65
T4303 3885-3891 Entity denotes Ser276
T4304 3893-3899 Entity denotes Ser529
T4305 3903-3909 Entity denotes Ser536
T4306 4024-4030 Entity denotes Ser276
T4307 4040-4043 Protein denotes p65
T4308 4047-4061 Phosphorylation denotes phosphorylated
T4309 4065-4069 Protein denotes MSK1
T4310 4205-4220 Phosphorylation denotes phosphorylation
T4311 4205-4220 Phosphorylation denotes phosphorylation
T4312 4224-4230 Entity denotes Ser276
T4313 4235-4241 Entity denotes Ser536
T4314 4250-4259 Regulation denotes regulated
T4315 4250-4259 Regulation denotes regulated
T4316 4295-4299 Protein denotes IKKβ
T4317 4348-4351 Protein denotes p65
T4318 4370-4384 Phosphorylation denotes phosphorylated
T4319 4388-4394 Entity denotes Ser536
T4320 4415-4418 Protein denotes p65
T4321 4419-4426 Entity denotes nuclear
T4322 4427-4440 Localization denotes translocation
T4323 4519-4522 Protein denotes p65
T4324 4523-4538 Phosphorylation denotes phosphorylation
T4325 4542-4548 Entity denotes Ser276
T4326 4622-4637 Phosphorylation denotes phosphorylation
T4327 4641-4647 Entity denotes Ser276
T4328 4657-4660 Protein denotes p65
T4329 4661-4663 Positive_regulation denotes by
T4330 4709-4713 Protein denotes p300
T4331 4850-4861 Positive_regulation denotes stabilizing
T4332 4862-4866 Protein denotes IκBα
T4333 4922-4927 Protein denotes Pim-1
T4334 4937-4951 Phosphorylation denotes phosphorylates
T4335 4958-4961 Protein denotes p65
T4336 4965-4971 Entity denotes Ser276
T4337 5195-5200 Protein denotes M-CSF
T4338 5556-5557 Protein denotes α
T4339 5558-5560 Protein denotes βI
T4340 5561-5564 Protein denotes βII
T4341 5569-5570 Protein denotes γ
T4342 5624-5625 Protein denotes δ
T4343 5627-5628 Protein denotes ε
T4344 5630-5631 Protein denotes η
T4345 5633-5634 Protein denotes θ
T4346 5639-5640 Protein denotes μ
T4347 5676-5677 Protein denotes ξ
T4348 5679-5680 Protein denotes ι
T4349 5685-5686 Protein denotes λ
T4350 5793-5797 Protein denotes PKCα
T4351 5798-5803 Protein denotes PKCβI
T4352 5808-5814 Protein denotes PKCβII
T4353 5832-5836 Protein denotes PKCδ
T4354 5841-5845 Protein denotes PKCε
T4355 5963-5967 Protein denotes PKCα
T4356 5968-5975 Positive_regulation denotes induces
T4357 5968-5975 Positive_regulation denotes induces
T4358 5968-5975 Positive_regulation denotes induces
T4359 5976-5981 Protein denotes IL-1α
T4360 5983-5987 Protein denotes iNOS
T4361 5992-5996 Protein denotes TNFα
T4362 6002-6012 Transcription denotes production
T4363 6002-6012 Transcription denotes production
T4364 6002-6012 Transcription denotes production
T4365 6131-6135 Protein denotes PKCα
T4366 6180-6184 Protein denotes PKCα
T4367 6188-6201 Positive_regulation denotes overexpressed
T4368 6298-6308 Negative_regulation denotes inhibition
T4369 6312-6316 Protein denotes PKCα
T4370 6325-6329 Protein denotes PKCδ
T4371 6445-6449 Protein denotes PKCδ
T4372 6516-6520 Protein denotes PKCδ
T4373 6530-6544 Phosphorylation denotes phosphorylates
T4374 6545-6554 Protein denotes caspase-3
T4375 6667-6671 Protein denotes PKCε
T4376 6787-6792 Protein denotes M-CSF
T4377 6904-6909 Protein denotes M-CSF
T4378 7042-7047 Protein denotes M-CSF
T4379 7425-7430 Protein denotes M-CSF
T4380 7484-7489 Protein denotes M-CSF
T4381 7654-7676 Protein denotes dominant negative PKCα
T4382 7691-7701 Protein denotes PKCα siRNA
T4383 7720-7729 Regulation denotes regulated
T4384 7766-7781 Phosphorylation denotes phosphorylation
T4385 7785-7791 Entity denotes Ser276
T4386 7801-7804 Protein denotes p65
T4387 7820-7825 Protein denotes M-CSF
T4388 7826-7835 Regulation denotes dependent
T4389 7917-7926 Regulation denotes regulated
T4390 7927-7942 Phosphorylation denotes phosphorylation
T4391 7946-7952 Entity denotes Ser276
T4392 7962-7965 Protein denotes p65
T5252 8087-8092 Protein denotes M-CSF
T5253 8235-8240 Protein denotes M-CSF
T5254 8340-8345 Protein denotes M-CSF
T5255 8496-8501 Protein denotes M-CSF
T5256 8677-8682 Protein denotes M-CSF
T5257 9025-9030 Protein denotes M-CSF
T23191 9088-9093 Protein denotes M-CSF
T23192 9215-9220 Protein denotes M-CSF
T23193 9476-9481 Protein denotes M-CSF
T23194 9929-9934 Protein denotes M-CSF
T5258 10103-10108 Protein denotes M-CSF
T5259 10302-10307 Protein denotes M-CSF
T5260 10337-10346 Positive_regulation denotes increased
T5261 10347-10352 Protein denotes NF-κB
T5262 10362-10370 Positive_regulation denotes activity
T5263 10451-10456 Protein denotes M-CSF
T6127 10667-10672 Protein denotes M-CSF
T6128 11031-11036 Protein denotes M-CSF
T6129 11194-11198 Protein denotes PKCα
T6130 11199-11200 Protein denotes β
T6131 11201-11210 Negative_regulation denotes inhibitor
T6132 11201-11210 Negative_regulation denotes inhibitor
T6133 11303-11308 Protein denotes M-CSF
T6134 11363-11368 Protein denotes M-CSF
T6135 11453-11458 Protein denotes M-CSF
T6136 11628-11633 Protein denotes M-CSF
T23512 11803-11808 Protein denotes M-CSF
T23513 11978-11983 Protein denotes M-CSF
T23514 12165-12170 Protein denotes M-CSF
T23515 12470-12475 Protein denotes M-CSF
T23516 12496-12501 Protein denotes M-CSF
T6137 12703-12708 Protein denotes M-CSF
T6138 12829-12838 Regulation denotes regulated true
T6139 12829-12838 Regulation denotes regulated true true
T6140 12845-12848 Protein denotes p65
T6141 12892-12897 Protein denotes c-Rel
T6142 12917-12922 Protein denotes c-Rel
T6143 13021-13026 Protein denotes M-CSF
T6144 13075-13085 Gene_expression denotes expressing
T6145 13086-13091 Protein denotes c-Rel
T6146 13142-13152 Regulation denotes functioned
T6147 13171-13174 Protein denotes p65
T6917 13264-13269 Protein denotes M-CSF
T6918 13365-13370 Protein denotes M-CSF
T6919 13446-13456 Positive_regulation denotes expression
T6920 13460-13467 Protein_catabolism denotes cleaved
T6921 13468-13477 Protein denotes caspase-3
T6922 13522-13530 Positive_regulation denotes presence
T6923 13534-13541 Negative_regulation denotes absence
T6924 13545-13550 Protein denotes M-CSF
T6925 13665-13670 Protein denotes M-CSF
T6926 13672-13679 Protein_catabolism denotes cleaved
T6927 13680-13689 Protein denotes caspase-3
T6928 13694-13702 Positive_regulation denotes elevated
T6929 13796-13801 Protein denotes M-CSF
T6930 13818-13822 Negative_regulation denotes less
T6931 13823-13830 Protein_catabolism denotes cleaved
T6932 13831-13840 Protein denotes caspase-3
T6933 13884-13889 Protein denotes M-CSF
T6934 13952-13957 Protein denotes M-CSF
T24050 14288-14293 Protein denotes M-CSF
T24051 14523-14530 Protein denotes β-actin
T24052 14578-14584 Positive_regulation denotes active
T24053 14585-14594 Protein denotes caspase-3
T24054 14622-14629 Protein denotes β-actin
T24055 14811-14820 Protein denotes Annexin V
T24056 14928-14937 Protein denotes Annexin V
T24057 14941-14949 Negative_regulation denotes negative
T24058 14986-14991 Protein denotes M-CSF
T24059 15122-15127 Protein denotes M-CSF
T24060 15148-15153 Protein denotes M-CSF
T6935 15248-15253 Protein denotes M-CSF
T6936 15339-15348 Protein denotes Annexin V
T6937 15396-15401 Protein denotes M-CSF
T6938 15402-15409 Negative_regulation denotes reduced
T6939 15424-15433 Protein denotes Annexin V
T6940 15437-15445 Negative_regulation denotes negative
T6941 15482-15487 Protein denotes M-CSF
T6942 15577-15582 Protein denotes M-CSF
T7411 15646-15651 Protein denotes M-CSF
T7412 15660-15664 Protein denotes PKCα
T7413 15778-15783 Protein denotes M-CSF
T7414 15865-15869 Protein denotes PKCα
T7415 15876-15893 Regulation denotes downstream target true
T7416 15897-15902 Protein denotes M-CSF
T7417 16337-16342 Protein denotes M-CSF
T24451 16623-16628 Protein denotes M-CSF
T24452 16629-16638 Positive_regulation denotes activates
T24453 16639-16643 Protein denotes PKCα
T24454 16677-16682 Protein denotes M-CSF
T24455 17052-17056 Protein denotes PKCα
T24456 17246-17250 Protein denotes PKCα
T24457 17298-17303 Protein denotes M-CSF
T24458 17397-17402 Protein denotes M-CSF
T7934 17454-17459 Protein denotes M-CSF
T7935 17497-17505 Regulation denotes Regulate true
T7936 17526-17529 Protein denotes p65
T7937 17530-17540 Positive_regulation denotes Activation
T7938 17590-17605 Phosphorylation denotes phosphorylation
T7939 17610-17621 Protein_catabolism denotes degradation
T7940 17625-17629 Protein denotes IκBα
T7941 17692-17695 Protein denotes p50
T7942 17696-17699 Protein denotes p65
T7943 17814-17819 Protein denotes M-CSF
T7944 17875-17879 Protein denotes IκBα
T7945 17880-17891 Protein_catabolism denotes degradation
T7946 17896-17905 Regulation denotes regulated true
T7947 17961-17968 Negative_regulation denotes inhibit
T7948 17977-17986 Gene_expression denotes synthesis
T7949 17990-17994 Protein denotes IκBα
T7950 18092-18097 Regulation denotes alter true
T7951 18098-18103 Protein denotes M-CSF
T7952 18104-18111 Positive_regulation denotes induced
T7953 18112-18116 Protein denotes IκBα
T7954 18117-18128 Protein_catabolism denotes degradation
T7955 18146-18151 Protein denotes M-CSF
T7956 18173-18182 Regulation denotes augmented
T7957 18246-18277 Protein_modification denotes post-translational modification
T7958 18287-18290 Protein denotes p65
T25060 18336-18341 Protein denotes M-CSF
T25061 18372-18380 Regulation denotes regulate true
T25062 18381-18385 Protein denotes IκBα
T25063 18386-18397 Protein_catabolism denotes degradation
T25064 18402-18411 Regulation denotes regulates
T25065 18416-18431 Phosphorylation denotes phosphorylation
T25066 18441-18444 Protein denotes p65
T25067 18448-18454 Entity denotes Ser276
T25068 18571-18576 Protein denotes M-CSF
T25069 18848-18853 Protein denotes M-CSF
T25070 18919-18926 Phosphorylation denotes phospho true
T25071 18927-18933 Entity denotes Ser276
T25072 18937-18944 Phosphorylation denotes phospho true
T25073 18945-18951 Entity denotes Ser536
T25074 18961-18964 Protein denotes p65
T25075 19039-19042 Protein denotes p65
T25076 19136-19143 Negative_regulation denotes absence
T25077 19147-19155 Positive_regulation denotes presence
T25078 19159-19164 Protein denotes M-CSF
T9200 19576-19581 Protein denotes M-CSF
T9201 19615-19621 Entity denotes Ser276
T9202 19655-19660 Protein denotes M-CSF
T9203 19698-19709 Regulation denotes influencing true
T9204 19710-19714 Protein denotes IκBα
T9205 19747-19752 Protein denotes M-CSF
T9206 19753-19761 Regulation denotes affected
T9207 19768-19771 Protein denotes p65
T9208 19775-19804 Protein_modification denotes post-translational mechanisms
T9209 19828-19843 Phosphorylation denotes phosphorylation true
T9210 19853-19856 Protein denotes p65
T9211 19871-19878 Phosphorylation denotes phospho
T9212 19871-19878 Phosphorylation denotes phospho
T9213 19884-19887 Protein denotes p65
T9214 19889-19895 Entity denotes Ser276
T9215 19900-19906 Entity denotes Ser536
T9216 19920-19925 Protein denotes M-CSF
T9217 19926-19933 Positive_regulation denotes induced
T9218 19926-19933 Positive_regulation denotes induced true
T9219 19938-19953 Phosphorylation denotes phosphorylation
T9220 19938-19953 Phosphorylation denotes phosphorylation
T9221 19957-19963 Entity denotes Ser276
T9222 19972-19978 Entity denotes Ser536
T9223 19988-19991 Protein denotes p65
T9224 20059-20066 Negative_regulation denotes reduced true
T9225 20059-20066 Negative_regulation denotes reduced
T9226 20067-20073 Entity denotes Ser276
T9227 20074-20089 Phosphorylation denotes phosphorylation
T9228 20099-20105 Entity denotes Ser536
T9229 20107-20122 Phosphorylation denotes phosphorylation
T9230 20126-20131 Protein denotes M-CSF
T9231 20175-20180 Protein denotes M-CSF
T9232 20181-20191 Positive_regulation denotes stimulated
T9233 20198-20201 Protein denotes p65
T9234 20202-20217 Phosphorylation denotes phosphorylation
T9235 20229-20235 Entity denotes Ser276
T9236 20268-20277 Regulation denotes dependent
T9237 20327-20336 Regulation denotes regulated
T9238 20327-20336 Regulation denotes regulated true
T9239 20337-20343 Entity denotes Ser276
T9240 20344-20359 Phosphorylation denotes phosphorylation
T9241 20344-20359 Phosphorylation denotes phosphorylation
T9242 20368-20374 Entity denotes Ser536
T9243 20422-20427 Protein denotes M-CSF
T9244 20428-20439 Positive_regulation denotes stimulation
T9245 20428-20439 Positive_regulation denotes stimulation
T9246 20507-20515 Localization denotes location true
T9247 20519-20533 Phosphorylation denotes phosphorylated
T9248 20540-20543 Protein denotes p65
T9249 20568-20582 Phosphorylation denotes phosphorylated true
T9250 20589-20592 Protein denotes p65
T9251 20597-20604 Localization denotes located
T9252 20608-20644 Entity denotes both cytosolic and nuclear fractions
T9253 20650-20664 Phosphorylation denotes phosphorylated
T9254 20650-20664 Phosphorylation denotes phosphorylated
T9255 20665-20671 Entity denotes Ser276
T9256 20676-20682 Entity denotes Ser536
T9257 20689-20692 Protein denotes p65
T9258 20707-20714 Localization denotes located
T9259 20718-20725 Entity denotes nuclear
T9260 20735-20740 Positive_regulation denotes after
T9261 20741-20746 Protein denotes M-CSF
T9262 20794-20809 Phosphorylation denotes phosphorylation
T9263 20813-20819 Entity denotes Ser536
T9264 20826-20829 Protein denotes p65
T9265 20880-20887 Negative_regulation denotes reduced
T9266 20888-20893 Protein denotes M-CSF
T9267 20894-20901 Positive_regulation denotes induced
T9268 20902-20908 Entity denotes Ser276
T9269 20909-20924 Phosphorylation denotes phosphorylation
T9270 20934-20937 Protein denotes p65
T9271 20989-20994 Protein denotes M-CSF
T9272 20995-21002 Positive_regulation denotes induced
T9273 21009-21012 Protein denotes p65
T9274 21013-21019 Entity denotes Ser536
T9275 21020-21035 Phosphorylation denotes phosphorylation
T9276 21063-21073 Regulation denotes regardless true
T9277 21126-21131 Protein denotes M-CSF
T9278 21132-21139 Positive_regulation denotes induced
T9279 21132-21139 Positive_regulation denotes induced
T9280 21140-21146 Entity denotes Ser276
T9281 21151-21157 Entity denotes Ser536
T9282 21162-21171 Regulation denotes regulated
T9283 21162-21171 Regulation denotes regulated
T9984 21378-21383 Protein denotes M-CSF
T9985 21524-21528 Protein denotes IκBα
T9986 21539-21546 Positive_regulation denotes induced
T9987 21623-21628 Protein denotes M-CSF
T9988 21862-21867 Protein denotes M-CSF
T9989 21869-21873 Protein denotes IκBα
T9990 21935-21940 Protein denotes M-CSF
T9991 21941-21949 Positive_regulation denotes enhanced
T9992 21950-21954 Protein denotes IκBα
T9993 21960-21970 Gene_expression denotes expression
T9994 22004-22013 Negative_regulation denotes decreased
T9995 22014-22018 Protein denotes IκBα
T9996 22024-22034 Gene_expression denotes expression
T25398 22202-22212 Negative_regulation denotes Inhibition
T25399 22216-22221 Protein denotes M-CSF
T25400 22417-22422 Protein denotes M-CSF
T25401 22555-22559 Protein denotes IκBα
T25402 22561-22567 Protein denotes BCL-xl
T25403 22614-22622 Positive_regulation denotes increase
T25404 22614-22622 Positive_regulation denotes increase
T25405 22626-22630 Protein denotes IκBα
T25406 22634-22640 Protein denotes BCL-xl
T25407 22646-22656 Gene_expression denotes expression
T25408 22646-22656 Gene_expression denotes expression
T9997 22849-22854 Protein denotes M-CSF
T9998 22872-22882 Gene_expression denotes expression true
T9999 22910-22916 Protein denotes BCL-xL
T10000 22932-22941 Regulation denotes regulated
T10001 22986-22993 Negative_regulation denotes reduced
T10002 22994-22999 Protein denotes M-CSF
T10003 23000-23010 Positive_regulation denotes stimulated
T10004 23011-23017 Protein denotes BCL-xL
T10005 23018-23028 Gene_expression denotes expression
T10006 23060-23065 Protein denotes M-CSF
T11959 23245-23249 Protein denotes PKCα
T11960 23250-23251 Protein denotes β
T11961 23252-23262 Negative_regulation denotes inhibitors
T11962 23252-23262 Negative_regulation denotes inhibitors
T11963 23308-23313 Protein denotes M-CSF
T11964 23348-23352 Protein denotes PKCα
T11965 23392-23397 Protein denotes M-CSF
T11966 23432-23436 Protein denotes PKCα
T11967 23509-23513 Protein denotes PKCα
T11968 23517-23533 Negative_regulation denotes kinase-deficient
T11969 23539-23543 Protein denotes PKCα
T11970 23548-23562 Gene_expression denotes co-transfected
T11971 23659-23673 Gene_expression denotes co-transfected
T11972 23698-23702 Protein denotes PKCα
T11973 23767-23772 Protein denotes M-CSF
T11974 23773-23783 Positive_regulation denotes activation
T11975 23830-23835 Protein denotes M-CSF
T11976 23919-23921 Negative_regulation denotes KD
T11977 23922-23926 Protein denotes PKCα
T11978 23959-23964 Protein denotes M-CSF
T11979 24003-24007 Protein denotes PKCα
T11980 24008-24019 Gene_expression denotes transfected
T11981 24066-24077 Gene_expression denotes transfected
T11982 24086-24090 Protein denotes PKCα
T11983 24146-24151 Protein denotes M-CSF
T11984 24152-24162 Positive_regulation denotes activation
T11985 24209-24220 Gene_expression denotes transfected
T11986 24229-24233 Protein denotes PKCα
T11987 24265-24267 Negative_regulation denotes KD
T11988 24268-24272 Protein denotes PKCα
T11989 24312-24317 Protein denotes M-CSF
T11990 24383-24394 Gene_expression denotes transfected
T11991 24403-24407 Protein denotes PKCα
T26274 24453-24457 Protein denotes PKCα
T26275 24458-24467 Regulation denotes regulates
T26276 24468-24483 Phosphorylation denotes phosphorylation
T26277 24493-24496 Protein denotes p65
T26278 24500-24506 Entity denotes Ser276
T26279 24556-24567 Gene_expression denotes transfected
T26280 24556-24567 Gene_expression denotes transfected
T26281 24606-24610 Protein denotes PKCα
T26282 24618-24634 Negative_regulation denotes kinase-deficient
T26283 24640-24644 Protein denotes PKCα
T26284 24716-24721 Protein denotes M-CSF
T26285 25021-25030 Protein denotes Annexin V
T26286 25253-25257 Protein denotes PKCα
T26287 25285-25295 Gene_expression denotes expression
T26288 25304-25308 Protein denotes PKCα
T26289 25321-25328 Protein denotes β-actin
T26290 25473-25484 Gene_expression denotes transfected
T26291 25529-25539 Protein denotes PKCα siRNA
T26292 25643-25648 Protein denotes M-CSF
T26293 25884-25893 Protein denotes Annexin V
T26294 26094-26101 Protein denotes β-actin
T11992 26249-26259 Gene_expression denotes expressing
T11993 26270-26274 Protein denotes PKCα
T11994 26278-26280 Negative_regulation denotes KD
T11995 26281-26285 Protein denotes PKCα
T11996 26300-26309 Protein denotes Annexin V
T11997 26345-26350 Protein denotes M-CSF
T11998 26404-26413 Protein denotes Annexin V
T11999 26417-26425 Negative_regulation denotes negative
T12000 26444-26454 Gene_expression denotes expression
T12001 26461-26465 Protein denotes PKCα
T12002 26525-26527 Negative_regulation denotes KD
T12003 26528-26532 Protein denotes PKCα
T12004 26543-26548 Protein denotes M-CSF
T12005 26625-26635 Gene_expression denotes expressing
T12006 26640-26644 Protein denotes PKCα
T12007 26719-26721 Negative_regulation denotes KD
T12008 26722-26726 Protein denotes PKCα
T12009 26754-26760 Regulation denotes affect true
T12010 26778-26793 Phosphorylation denotes phosphorylation
T12011 26797-26803 Entity denotes Ser536
T12012 26813-26816 Protein denotes p65
T12013 26822-26832 Negative_regulation denotes attenuated
T12014 26837-26852 Phosphorylation denotes phosphorylation
T12015 26856-26862 Entity denotes Ser276
T12016 26864-26874 Gene_expression denotes Expression
T12017 26881-26885 Protein denotes PKCα
T12018 26894-26900 Regulation denotes effect true
T12019 26894-26900 Regulation denotes effect true
T12020 26905-26920 Phosphorylation denotes phosphorylation
T12021 26905-26920 Phosphorylation denotes phosphorylation
T12022 26939-26954 Regulation denotes with or without true
T12023 26939-26954 Regulation denotes with or without true
T12024 26955-26960 Protein denotes M-CSF
T12025 27010-27014 Protein denotes PKCα
T12026 27031-27036 Protein denotes M-CSF
T12027 27111-27126 Phosphorylation denotes phosphorylation
T12028 27130-27136 Entity denotes Ser276
T12029 27146-27149 Protein denotes p65
T12030 27187-27191 Protein denotes PKCα
T12031 27202-27207 Protein denotes M-CSF
T12032 27265-27275 Protein denotes PKCα siRNA
T12033 27326-27336 Protein denotes PKCα siRNA
T12034 27389-27397 Positive_regulation denotes presence
T12035 27401-27408 Negative_regulation denotes absence
T12036 27412-27417 Protein denotes M-CSF
T12037 27419-27427 Negative_regulation denotes Reducing
T12038 27435-27439 Protein denotes PKCα
T12039 27440-27450 Gene_expression denotes expression
T12040 27461-27466 Protein denotes M-CSF
T12041 27632-27641 Protein denotes Annexin V
T12042 27669-27679 Protein denotes PKCα siRNA
T12043 27717-27722 Protein denotes M-CSF
T12044 27786-27796 Protein denotes PKCα siRNA
T12045 27893-27903 Protein denotes PKCα siRNA
T12046 27917-27926 Negative_regulation denotes decreased
T12047 27927-27931 Protein denotes PKCα
T12048 27940-27950 Gene_expression denotes expression
T12049 28011-28015 Protein denotes PKCα
T12050 28047-28052 Protein denotes M-CSF
T13901 28125-28130 Protein denotes M-CSF
T13902 28154-28165 Positive_regulation denotes facilitated
T13903 28154-28165 Positive_regulation denotes facilitated true
T13904 28172-28175 Protein denotes p65
T13905 28176-28191 Phosphorylation denotes phosphorylation
T13906 28176-28191 Phosphorylation denotes phosphorylation
T13907 28195-28201 Entity denotes Ser276
T13908 28210-28216 Entity denotes Ser536
T13909 28249-28252 Protein denotes p65
T13910 28253-28259 Entity denotes Ser276
T13911 28260-28275 Phosphorylation denotes phosphorylation
T13912 28298-28312 Gene_expression denotes co-transfected
T13913 28298-28312 Gene_expression denotes co-transfected
T13914 28359-28362 Protein denotes p65
T13915 28372-28375 Protein denotes p65
T13916 28474-28481 Negative_regulation denotes absence
T13917 28485-28494 Positive_regulation denotes presences
T13918 28498-28503 Protein denotes M-CSF
T13919 28582-28587 Protein denotes M-CSF
T13920 28645-28650 Protein denotes M-CSF
T13921 28710-28720 Gene_expression denotes expressing
T13922 28730-28733 Protein denotes p65
T13923 28735-28738 Protein denotes p65
T13924 28868-28880 Gene_expression denotes introduction
T13925 28890-28893 Protein denotes p65
T13926 28976-28979 Protein denotes p65
T13927 29006-29011 Protein denotes M-CSF
T26782 29112-29115 Protein denotes p65
T26783 29206-29217 Gene_expression denotes transfected
T26784 29206-29217 Gene_expression denotes transfected
T26785 29292-29295 Protein denotes p65
T26786 29308-29311 Protein denotes p65
T26787 29487-29492 Protein denotes M-CSF
T26788 29562-29565 Protein denotes p65
T26789 29595-29606 Gene_expression denotes transfected
T26790 29595-29606 Gene_expression denotes transfected
T26791 29595-29606 Gene_expression denotes transfected
T26792 29681-29684 Protein denotes p65
T26793 29695-29698 Protein denotes p65
T26794 29716-29719 Protein denotes p65
T26795 29982-29985 Protein denotes p65
T26796 30015-30026 Gene_expression denotes transfected
T26797 30015-30026 Gene_expression denotes transfected
T26798 30102-30105 Protein denotes p65
T26799 30118-30121 Protein denotes p65
T26800 30296-30300 Protein denotes TNFα
T13928 30591-30605 Gene_expression denotes co-transfected
T13929 30591-30605 Gene_expression denotes co-transfected
T13930 30662-30665 Protein denotes p65
T13931 30673-30676 Protein denotes p65
T13932 30693-30696 Protein denotes p65
T13933 30728-30731 Protein denotes p65
T13934 30731-30734 Gene_expression denotes −/− true
T13935 30806-30816 Gene_expression denotes expression
T13936 30829-30832 Protein denotes p65
T13937 30834-30837 Protein denotes p65
T13938 30851-30854 Protein denotes p65
T13939 30854-30857 Gene_expression denotes −/− true
T13940 31001-31013 Gene_expression denotes transfecting
T13941 31024-31027 Protein denotes p65
T13942 31099-31102 Protein denotes p65
T13943 31113-31116 Protein denotes p65
T13944 31132-31142 Gene_expression denotes expressing
T13945 31153-31156 Protein denotes p65
T13946 31206-31209 Protein denotes p65
T13947 31209-31212 Gene_expression denotes −/− true
T13948 31249-31252 Protein denotes p65
T13949 31253-31264 Gene_expression denotes transfected
T13950 31278-31283 Protein denotes M-CSF
T13951 31360-31363 Protein denotes p65
T13952 31450-31453 Protein denotes p65
T13953 31453-31456 Gene_expression denotes −/− true
T13954 31519-31523 Protein denotes TNFα
T13955 31569-31572 Protein denotes p65
T13956 31582-31585 Protein denotes p65
T13957 31593-31604 Gene_expression denotes transfected
T13958 31593-31604 Gene_expression denotes transfected
T13959 31624-31628 Protein denotes TNFα
T13960 31696-31700 Protein denotes TNFα
T13961 31735-31738 Protein denotes p65
T13962 31738-31741 Gene_expression denotes −/− true
T13963 31748-31758 Gene_expression denotes expressing
T13964 31762-31765 Protein denotes p65
T13965 31868-31879 Gene_expression denotes Introducing
T13966 31886-31889 Protein denotes p65
T13967 31973-31976 Protein denotes p65
T13968 32009-32013 Protein denotes TNFα
T13969 32061-32064 Protein denotes p65
T13970 32064-32067 Gene_expression denotes −/− true
T13971 32074-32084 Gene_expression denotes expressing
T13972 32091-32094 Protein denotes p65
T13973 32160-32174 Gene_expression denotes overexpressing
T13974 32185-32188 Protein denotes p65
T13975 32251-32254 Protein denotes p65
T13976 32347-32357 Regulation denotes modulating
T13977 32362-32377 Phosphorylation denotes phosphorylation
T13978 32387-32390 Protein denotes p65
T13979 32394-32400 Entity denotes Ser276
T18164 32623-32626 Protein denotes p50
T18165 32627-32630 Protein denotes p65
T18166 32644-32655 Localization denotes translocate
T18167 32644-32655 Localization denotes translocate
T18168 32663-32670 Entity denotes nucleus
T18169 32700-32705 Protein denotes their
T18170 32706-32719 Localization denotes translocation
T18171 33114-33119 Protein denotes M-CSF
T18172 33264-33269 Protein denotes M-CSF
T18173 33270-33280 Positive_regulation denotes stimulated
T18174 33281-33285 Protein denotes PKCα
T18175 33440-33456 Negative_regulation denotes kinase deficient
T18176 33457-33461 Protein denotes PKCα
T18177 33465-33475 Protein denotes PKCα siRNA
T18178 33484-33489 Protein denotes M-CSF
T18179 33578-33587 Negative_regulation denotes reduction
T18180 33591-33596 Protein denotes M-CSF
T18181 33597-33604 Positive_regulation denotes induced
T18182 33605-33620 Phosphorylation denotes phosphorylation
T18183 33630-33633 Protein denotes p65
T18184 33637-33643 Entity denotes Ser276
T18185 33680-33702 Protein denotes dominant negative PKCα
T18186 33719-33728 Negative_regulation denotes inhibited true
T18187 33719-33728 Negative_regulation denotes inhibited
T18188 33735-33738 Protein denotes p65
T18189 33739-33754 Phosphorylation denotes phosphorylation
T18190 33739-33754 Phosphorylation denotes phosphorylation
T18191 33758-33764 Entity denotes Ser276
T18192 33776-33782 Entity denotes Ser536
T18193 33841-33846 Protein denotes M-CSF
T18194 33935-33940 Protein denotes M-CSF
T18195 33984-33994 Positive_regulation denotes activating
T18196 34001-34004 Protein denotes p65
T18197 34005-34020 Phosphorylation denotes phosphorylation
T18198 34024-34030 Entity denotes Ser276
T18199 34060-34063 Protein denotes p65
T18200 34063-34066 Gene_expression denotes −/− true
T18201 34135-34138 Protein denotes p65
T26916 34374-34379 Protein denotes M-CSF
T26917 34428-34438 Positive_regulation denotes activating
T26918 34445-34448 Protein denotes p65
T26919 34449-34464 Phosphorylation denotes phosphorylation
T26920 34468-34474 Entity denotes Ser276
T18202 34478-34509 Protein_modification denotes Post-translational modification
T18203 34519-34522 Protein denotes p65
T18204 34630-34633 Protein denotes p65
T18205 34795-34809 Positive_regulation denotes in response to
T18206 34821-34824 Protein denotes p65
T18207 34828-34842 Phosphorylation denotes phosphorylated
T18208 34867-34873 Entity denotes Ser276
T18209 34940-34946 Entity denotes Ser276
T18210 34954-34968 Phosphorylation denotes phosphorylated
T18211 34972-34976 Protein denotes MSK1
T18212 34992-34996 Positive_regulation denotes upon
T18213 34997-35001 Protein denotes TNFα
T18214 35018-35033 Phosphorylation denotes Phosphorylation
T18215 35043-35046 Protein denotes p65
T18216 35050-35056 Entity denotes Ser536
T18217 35064-35078 Positive_regulation denotes in response to
T18218 35125-35129 Protein denotes IKKα
T18219 35131-35135 Protein denotes IKKβ
T18220 35140-35144 Protein denotes RSK1
T18221 35256-35261 Protein denotes M-CSF
T18222 35267-35276 Regulation denotes modulated
T18223 35281-35296 Phosphorylation denotes phosphorylation
T18224 35310-35313 Protein denotes p65
T18225 35325-35331 Entity denotes Ser536
T18226 35360-35376 Negative_regulation denotes kinase deficient
T18227 35377-35381 Protein denotes PKCα
T18228 35477-35491 Regulation denotes point mutation
T18229 35495-35501 Entity denotes Ser536
T18230 35511-35514 Protein denotes p65
T18231 35554-35561 Negative_regulation denotes lacking
T18232 35579-35582 Protein denotes p65
T18233 35600-35603 Protein denotes p65
T18234 35683-35714 Protein_modification denotes post-translational modification
T18235 35724-35727 Protein denotes p65
T18236 35840-35845 Protein denotes M-CSF
T18237 35846-35855 Positive_regulation denotes activated
T18238 35862-35865 Protein denotes p65
T18239 35866-35872 Entity denotes Ser276
T18240 35873-35888 Phosphorylation denotes phosphorylation
T18241 35925-35929 Protein denotes PKCα
T18242 35930-35939 Regulation denotes dependent
T18243 35948-35952 Protein denotes PKCα
T18244 36082-36086 Protein denotes PKCα
T18245 36205-36215 Gene_expression denotes Expression
T18246 36219-36223 Protein denotes PKCα
T18247 36281-36285 Protein denotes PKCα
T18248 36286-36296 Negative_regulation denotes inhibition
T18249 36388-36410 Protein denotes dominant negative PKCα
T18250 36423-36427 Protein denotes PKCα
T18251 36444-36449 Protein denotes M-CSF
T18252 36481-36489 Positive_regulation denotes inducing
T18253 36490-36496 Entity denotes Ser276
T18254 36497-36512 Phosphorylation denotes phosphorylation
T18255 36522-36525 Protein denotes p65
T18256 36610-36623 Negative_regulation denotes downregulated
T18257 36630-36639 Positive_regulation denotes induction
T18258 36667-36673 Protein denotes BCL-xL
T18259 36964-36979 Phosphorylation denotes phosphorylation
T18260 36983-36986 Protein denotes p65
T18261 36990-36996 Entity denotes Ser276
T18262 36997-37005 Negative_regulation denotes prevents
T18263 37010-37021 Protein_catabolism denotes degradation
T18264 37022-37024 Positive_regulation denotes by
T18265 37025-37034 Protein denotes ubiquitin
T18266 37035-37043 Positive_regulation denotes mediated
T18267 37044-37055 Protein_catabolism denotes proteolysis
T18268 37118-37124 Protein denotes BCL-xL
T18269 37125-37135 Gene_expression denotes expression
T18270 37202-37206 Protein denotes PKCα
T18271 37282-37287 Protein denotes M-CSF
T18272 37452-37457 Protein denotes M-CSF
T18273 37538-37542 Protein denotes PKCα
T18274 37595-37600 Protein denotes PKCβI
T18275 37601-37604 Protein denotes βII
T18276 37653-37658 Protein denotes PKCβI
T18277 37659-37662 Protein denotes βII
T18278 37676-37685 Gene_expression denotes expressed
T18279 37676-37685 Gene_expression denotes expressed
T18280 37775-37781 Gene_expression denotes devoid true
T18281 37796-37802 Protein denotes PKCβII
T18282 37819-37823 Protein denotes TNFα
T18283 37851-37861 Gene_expression denotes expression
T18284 37865-37871 Protein denotes PKCβII
T18285 37921-37925 Protein denotes TNFα
T18286 37958-37964 Protein denotes PKCβII
T18287 38118-38133 Phosphorylation denotes phosphorylation
T18288 38147-38150 Protein denotes p65
T18289 38166-38173 Negative_regulation denotes absence
T18290 38177-38181 Protein denotes IκBα
T18291 38182-38193 Protein_catabolism denotes degradation
T18292 38441-38472 Protein_modification denotes post-translational modification
T18293 38482-38485 Protein denotes p65
T18294 38490-38496 Regulation denotes affect true
T18295 38501-38512 Binding denotes interaction
T18296 38604-38612 Regulation denotes involved true
T18297 38604-38612 Regulation denotes involved true
T18298 38616-38620 Protein denotes IκBα
T18299 38621-38632 Protein_catabolism denotes degradation
T18300 38642-38645 Protein denotes p65
T18301 38646-38653 Entity denotes nuclear
T18302 38654-38667 Localization denotes translocation
T18303 38668-38675 Positive_regulation denotes induced
T18304 38679-38684 Protein denotes M-CSF
T18305 38695-38700 Protein denotes M-CSF
T18306 38701-38708 Positive_regulation denotes induced
T18307 38709-38724 Phosphorylation denotes phosphorylation
T18308 38734-38737 Protein denotes p65
T18309 38741-38747 Entity denotes Ser276
T18310 38765-38772 Negative_regulation denotes reduced
T18311 38765-38772 Negative_regulation denotes reduced
T18312 38811-38827 Negative_regulation denotes kinase deficient
T18313 38828-38832 Protein denotes PKCα
T18314 38840-38845 Protein denotes siRNA
T18315 38854-38858 Protein denotes PKCα
T18316 39005-39010 Protein denotes M-CSF
T18317 39179-39189 Gene_expression denotes expression
T18318 39193-39197 Protein denotes IKKα
T18319 39223-39231 Positive_regulation denotes elevated
T18320 39243-39252 Positive_regulation denotes increased
T18321 39253-39256 Protein denotes p52
T18322 39264-39268 Protein denotes relB
T18323 39270-39280 Gene_expression denotes expression
T18324 39281-39288 Positive_regulation denotes through
T18325 39309-39320 Protein_catabolism denotes degradation
T18326 39328-39332 Protein denotes p100
T18327 39374-39379 Protein denotes M-CSF
T18328 39537-39542 Protein denotes M-CSF
T18329 39543-39550 Negative_regulation denotes reduced
T18330 39543-39550 Negative_regulation denotes reduced
T18331 39551-39560 Protein denotes caspase-3
T18332 39565-39567 Protein denotes -9
T18333 39717-39733 Negative_regulation denotes kinase-deficient
T18334 39734-39738 Protein denotes PKCα
T18335 39747-39752 Protein denotes M-CSF
T18336 39865-39870 Protein denotes M-CSF
T18337 39875-39882 Positive_regulation denotes mediate
T18338 39902-39912 Positive_regulation denotes activation
T18339 39922-39925 Protein denotes p65
T18340 39929-39944 Phosphorylation denotes phosphorylating
T18341 39945-39951 Entity denotes Ser276
T19395 40156-40161 Protein denotes M-CSF
T19396 40744-40754 Protein denotes PKCα siRNA
T19397 41049-41052 Protein denotes p65
T19398 41061-41064 Protein denotes p65
T19399 41080-41083 Protein denotes p65
T19400 41176-41192 Negative_regulation denotes Kinase deficient
T19401 41197-41201 Protein denotes PKCα
T19402 41203-41205 Negative_regulation denotes KD
T19403 41206-41210 Protein denotes PKCα
T19404 41230-41234 Protein denotes PKCα
T19405 41239-41243 Protein denotes PKCα
T19406 41333-41337 Protein denotes IκBα
T19407 41461-41480 Protein denotes PKCα specific siRNA
T19651 41919-41922 Protein denotes p65
T19652 41924-41927 Protein denotes p65
T19908 42357-42361 Protein denotes CD14
T19909 42658-42663 Protein denotes M-CSF
T20780 44039-44054 Gene_expression denotes co-transfection
T20781 44039-44054 Gene_expression denotes co-transfection
T20782 44064-44068 Protein denotes PKCα
T20783 44078-44081 Protein denotes p65
T20784 44183-44193 Protein denotes PKCα siRNA
T20785 44387-44392 Protein denotes M-CSF
T20786 44555-44560 Protein denotes M-CSF
T20787 44643-44646 Protein denotes GFP
T20788 44647-44657 Gene_expression denotes expression
T21286 45017-45027 Protein denotes PKCα siRNA
T21287 45126-45130 Protein denotes PKCα
T21288 45140-45143 Protein denotes p65
T21289 45500-45505 Protein denotes M-CSF
T21290 45633-45642 Protein denotes Annexin V
T21291 45791-45796 Protein denotes M-CSF
T21724 46185-46194 Protein denotes Annexin V
T21725 46288-46297 Protein denotes Annexin V
T21726 46487-46492 Protein denotes M-CSF
T21727 46610-46619 Protein denotes Annexin V
T21728 46693-46702 Protein denotes Annexin V
T22359 47367-47371 Protein denotes PKCα
T22360 47448-47453 Protein denotes M-CSF
T22361 47883-47887 Protein denotes PKCα
T22685 48602-48607 Protein denotes M-CSF
R10293 T13901 T13902 causeOf M-CSF,facilitated
R10294 T13901 T13903 causeOf M-CSF,facilitated
R10295 T13905 T13902 themeOf phosphorylation,facilitated
R10296 T13906 T13903 themeOf phosphorylation,facilitated
R10297 T13907 T13905 themeOf Ser276,phosphorylation
R10298 T13907 T13904 partOf Ser276,p65
R10299 T13908 T13906 themeOf Ser536,phosphorylation
R10300 T13908 T13904 partOf Ser536,p65
R10301 T13910 T13909 partOf Ser276,p65
R10302 T13910 T13911 themeOf Ser276,phosphorylation
R10303 T13914 T13912 themeOf p65,co-transfected
R10304 T13915 T13913 themeOf p65,co-transfected
R10305 T13918 T13917 themeOf M-CSF,presences
R10306 T13918 T13916 themeOf M-CSF,absence
R10307 T13922 T13921 themeOf p65,expressing
R10308 T13923 T13922 equivalentTo p65,p65
R10309 T13925 T13924 themeOf p65,introduction
R10310 T13931 T13928 themeOf p65,co-transfected
R10311 T13932 T13929 themeOf p65,co-transfected
R10312 T13933 T13934 themeOf p65,−/−
R10313 T13936 T13935 themeOf p65,expression
R10314 T13937 T13936 equivalentTo p65,p65
R10315 T13938 T13939 themeOf p65,−/−
R10316 T13941 T13940 themeOf p65,transfecting
R10317 T13945 T13944 themeOf p65,expressing
R10318 T13946 T13947 themeOf p65,−/−
R10319 T13948 T13949 themeOf p65,transfected
R10320 T13952 T13953 themeOf p65,−/−
R10321 T13955 T13957 themeOf p65,transfected
R10322 T13956 T13958 themeOf p65,transfected
R10323 T13961 T13962 themeOf p65,−/−
R10324 T13964 T13963 themeOf p65,expressing
R10325 T13966 T13965 themeOf p65,Introducing
R10326 T13969 T13970 themeOf p65,−/−
R10327 T13972 T13971 themeOf p65,expressing
R10328 T13974 T13973 themeOf p65,overexpressing
R10329 T13977 T13976 themeOf phosphorylation,modulating
R10330 T13979 T13977 themeOf Ser276,phosphorylation
R10331 T13979 T13978 partOf Ser276,p65
R13632 T18164 T18166 themeOf p50,translocate
R13633 T18165 T18167 themeOf p65,translocate
R13635 T18168 T18166 locationOf nucleus,translocate
R13636 T18168 T18167 locationOf nucleus,translocate
R13638 T18169 T18170 themeOf their,translocation
R13640 T18172 T18173 causeOf M-CSF,stimulated
R13642 T18174 T18173 themeOf PKCα,stimulated
R13644 T18176 T18175 themeOf PKCα,kinase deficient
R13648 T18180 T18181 causeOf M-CSF,induced
R13649 T18181 T18179 themeOf induced,reduction
R13650 T18182 T18181 themeOf phosphorylation,induced
R13651 T18184 T18182 themeOf Ser276,phosphorylation
R13652 T18184 T18183 partOf Ser276,p65
R13653 T18185 T18187 causeOf dominant negative PKCα,inhibited
R13654 T18185 T18186 causeOf dominant negative PKCα,inhibited
R13656 T18189 T18187 themeOf phosphorylation,inhibited
R13657 T18190 T18186 themeOf phosphorylation,inhibited
R13658 T18191 T18189 themeOf Ser276,phosphorylation
R13659 T18191 T18188 partOf Ser276,p65
R13661 T18192 T18190 themeOf Ser536,phosphorylation
R13662 T18192 T18188 partOf Ser536,p65
R13664 T18197 T18195 themeOf phosphorylation,activating
R13666 T18198 T18197 themeOf Ser276,phosphorylation
R13667 T18198 T18196 partOf Ser276,p65
R13668 T18199 T18200 themeOf p65,−/−
R13671 T18203 T18202 themeOf p65,Post-translational modification
R13674 T18207 T18205 themeOf phosphorylated,in response to
R13675 T18208 T18207 themeOf Ser276,phosphorylated
R13676 T18208 T18206 partOf Ser276,p65
R13677 T18209 T18210 themeOf Ser276,phosphorylated
R13678 T18209 T18206 partOf Ser276,p65
R13680 T18210 T18212 themeOf phosphorylated,upon
R13681 T18211 T18210 causeOf MSK1,phosphorylated
R13683 T18213 T18212 causeOf TNFα,upon
R13684 T18214 T18217 themeOf Phosphorylation,in response to
R13686 T18216 T18214 themeOf Ser536,Phosphorylation
R13687 T18216 T18215 partOf Ser536,p65
R13689 T18221 T18222 causeOf M-CSF,modulated
R13692 T18223 T18222 themeOf phosphorylation,modulated
R13693 T18225 T18223 themeOf Ser536,phosphorylation
R13694 T18225 T18224 partOf Ser536,p65
R13695 T18227 T18226 themeOf PKCα,kinase deficient
R13697 T18229 T18228 themeOf Ser536,point mutation
R13698 T18229 T18230 partOf Ser536,p65
R13700 T18232 T18231 themeOf p65,lacking
R13702 T18235 T18234 themeOf p65,post-translational modification
R13703 T18236 T18237 causeOf M-CSF,activated
R13704 T18237 T18242 themeOf activated,dependent
R13705 T18239 T18240 themeOf Ser276,phosphorylation
R13706 T18239 T18238 partOf Ser276,p65
R13707 T18240 T18237 themeOf phosphorylation,activated
R13709 T18241 T18242 causeOf PKCα,dependent
R13712 T18246 T18245 themeOf PKCα,Expression
R13713 T18247 T18248 themeOf PKCα,inhibition
R13715 T18250 T18252 causeOf PKCα,inducing
R13717 T18253 T18254 themeOf Ser276,phosphorylation
R13718 T18253 T18255 partOf Ser276,p65
R13719 T18254 T18252 themeOf phosphorylation,inducing
R13724 T18257 T18256 themeOf induction,downregulated
R13725 T18258 T18257 themeOf BCL-xL,induction
R13726 T18259 T18262 causeOf phosphorylation,prevents
R13727 T18260 T18263 themeOf p65,degradation
R13728 T18260 T18267 themeOf p65,proteolysis
R13729 T18261 T18259 themeOf Ser276,phosphorylation
R13730 T18261 T18260 partOf Ser276,p65
R13732 T18263 T18264 themeOf degradation,by
R13734 T18264 T18262 themeOf by,prevents
R13735 T18265 T18266 causeOf ubiquitin,mediated
R13736 T18266 T18264 causeOf mediated,by
R13737 T18267 T18266 themeOf proteolysis,mediated
R13739 T18268 T18269 themeOf BCL-xL,expression
R13745 T18276 T18278 themeOf PKCβI,expressed
R13747 T18277 T18279 themeOf βII,expressed
R13748 T18281 T18280 themeOf PKCβII,devoid
R13749 T18284 T18283 themeOf PKCβII,expression
R13751 T18288 T18287 themeOf p65,phosphorylation
R13753 T18290 T18291 themeOf IκBα,degradation
R13754 T18291 T18289 themeOf degradation,absence
R13755 T18292 T18294 causeOf post-translational modification,affect
R13756 T18293 T18292 themeOf p65,post-translational modification
R13757 T18293 T18295 themeOf p65,interaction
R13758 T18295 T18294 themeOf interaction,affect
R13759 T18298 T18299 themeOf IκBα,degradation
R13760 T18299 T18296 themeOf degradation,involved
R13761 T18300 T18302 themeOf p65,translocation
R13763 T18301 T18302 locationOf nuclear,translocation
R13764 T18302 T18303 themeOf translocation,induced
R13765 T18303 T18297 themeOf induced,involved
R13766 T18303 T18306 themeOf induced,induced
R13767 T18304 T18303 causeOf M-CSF,induced
R13768 T18305 T18306 causeOf M-CSF,induced
R13770 T18306 T18310 themeOf induced,reduced
R13771 T18306 T18311 themeOf induced,reduced
R13772 T18309 T18307 themeOf Ser276,phosphorylation
R13773 T18309 T18308 partOf Ser276,p65
R13775 T18312 T18310 causeOf kinase deficient,reduced
R13776 T18313 T18312 themeOf PKCα,kinase deficient
R13778 T18314 T18311 causeOf siRNA,reduced
R13781 T18317 T18320 causeOf expression,increased
R13782 T18317 T18319 themeOf expression,elevated
R13783 T18318 T18317 themeOf IKKα,expression
R13785 T18320 T18324 themeOf increased,through
R13787 T18321 T18323 themeOf p52,expression
R13788 T18322 T18321 equivalentTo relB,p52
R13789 T18323 T18320 themeOf expression,increased
R13790 T18325 T18324 causeOf degradation,through
R13792 T18326 T18325 themeOf p100,degradation
R13794 T18328 T18329 causeOf M-CSF,reduced
R13795 T18328 T18330 causeOf M-CSF,reduced
R13796 T18331 T18329 themeOf caspase-3,reduced
R13798 T18332 T18330 themeOf -9,reduced
R13800 T18334 T18333 themeOf PKCα,kinase-deficient
R13803 T18338 T18337 themeOf activation,mediate
R13804 T18339 T18338 themeOf p65,activation
R13805 T18340 T18338 causeOf phosphorylating,activation
R13806 T18341 T18340 themeOf Ser276,phosphorylating
R13807 T18341 T18339 partOf Ser276,p65
R14471 T19401 T19400 themeOf PKCα,Kinase deficient
R14472 T19403 T19402 themeOf PKCα,KD
R15651 T20782 T20780 themeOf PKCα,co-transfection
R15652 T20783 T20781 themeOf p65,co-transfection
R15653 T20787 T20788 themeOf GFP,expression
R18353 T24053 T24052 themeOf caspase-3,active
R18354 T24056 T24057 themeOf Annexin V,negative
R18656 T24451 T24452 causeOf M-CSF,activates
R18657 T24453 T24452 themeOf PKCα,activates
R19152 T25060 T25061 causeOf M-CSF,regulate
R19153 T25060 T25064 causeOf M-CSF,regulates
R19154 T25062 T25063 themeOf IκBα,degradation
R19155 T25063 T25061 themeOf degradation,regulate
R19156 T25065 T25064 themeOf phosphorylation,regulates
R19157 T25067 T25065 themeOf Ser276,phosphorylation
R19158 T25067 T25066 partOf Ser276,p65
R19159 T25071 T25070 themeOf Ser276,phospho
R19160 T25071 T25074 partOf Ser276,p65
R19161 T25073 T25072 themeOf Ser536,phospho
R19162 T25073 T25074 partOf Ser536,p65
R19163 T25078 T25077 themeOf M-CSF,presence
R19164 T25078 T25076 themeOf M-CSF,absence
R19401 T25399 T25398 themeOf M-CSF,Inhibition
R19402 T25405 T25407 themeOf IκBα,expression
R19403 T25406 T25408 themeOf BCL-xl,expression
R19404 T25407 T25403 themeOf expression,increase
R19405 T25408 T25404 themeOf expression,increase
R20120 T26274 T26275 causeOf PKCα,regulates
R20121 T26276 T26275 themeOf phosphorylation,regulates
R20122 T26278 T26276 themeOf Ser276,phosphorylation
R20123 T26278 T26277 partOf Ser276,p65
R20124 T26281 T26279 themeOf PKCα,transfected
R20125 T26283 T26280 themeOf PKCα,transfected
R20126 T26283 T26282 themeOf PKCα,kinase-deficient
R20127 T26288 T26287 themeOf PKCα,expression
R20128 T26291 T26290 themeOf PKCα siRNA,transfected
R20458 T26785 T26783 themeOf p65,transfected
R20459 T26786 T26784 themeOf p65,transfected
R20460 T26792 T26789 themeOf p65,transfected
R20461 T26793 T26790 themeOf p65,transfected
R20462 T26794 T26791 themeOf p65,transfected
R20463 T26798 T26796 themeOf p65,transfected
R20464 T26799 T26797 themeOf p65,transfected
R20524 T26919 T26917 themeOf phosphorylation,activating
R20525 T26920 T26919 themeOf Ser276,phosphorylation
R20526 T26920 T26918 partOf Ser276,p65
R3218 T4263 T4262 equivalentTo M-CSF,Macrophage colony-stimulating factor
R3219 T4266 T4267 equivalentTo RelA,p65
R3228 T4277 T4276 themeOf p65,lacking
R3245 T4278 T4279 themeOf p65,null
R3248 T4282 T4281 themeOf p65,overexpressing
R3251 T4288 T4290 themeOf IκBα,degraded
R3254 T4288 T4289 themeOf IκBα,phosphorylated
R3255 T4289 T4286 themeOf phosphorylated,Upon
R3256 T4290 T4287 themeOf degraded,Upon
R3257 T4295 T4293 themeOf p65,release
R3261 T4295 T4296 themeOf p65,post-translational modification
R3262 T4297 T4298 themeOf p65,phosphorylation
R3266 T4303 T4299 themeOf Ser276,phosphorylation
R3272 T4303 T4302 partOf Ser276,p65
R3273 T4304 T4300 themeOf Ser529,phosphorylation
R3275 T4304 T4302 partOf Ser529,p65
R3277 T4305 T4301 themeOf Ser536,phosphorylation
R3278 T4305 T4302 partOf Ser536,p65
R3279 T4306 T4308 themeOf Ser276,phosphorylated
R3280 T4306 T4307 partOf Ser276,p65
R3281 T4309 T4308 causeOf MSK1,phosphorylated
R3286 T4310 T4314 themeOf phosphorylation,regulated
R3287 T4311 T4315 themeOf phosphorylation,regulated
R3288 T4312 T4310 themeOf Ser276,phosphorylation
R3289 T4312 T4307 partOf Ser276,p65
R3290 T4313 T4311 themeOf Ser536,phosphorylation
R3291 T4313 T4307 partOf Ser536,p65
R3292 T4316 T4314 causeOf IKKβ,regulated
R3293 T4355 T4356 causeOf PKCα,induces
R3294 T4355 T4357 causeOf PKCα,induces
R3295 T4355 T4358 causeOf PKCα,induces
R3296 T4316 T4315 causeOf IKKβ,regulated
R3297 T4319 T4318 themeOf Ser536,phosphorylated
R3298 T4359 T4362 themeOf IL-1α,production
R3299 T4360 T4363 themeOf iNOS,production
R3300 T4361 T4364 themeOf TNFα,production
R3301 T4362 T4356 themeOf production,induces
R3302 T4363 T4357 themeOf production,induces
R3303 T4319 T4317 partOf Ser536,p65
R3304 T4364 T4358 themeOf production,induces
R3305 T4320 T4322 themeOf p65,translocation
R3306 T4366 T4367 themeOf PKCα,overexpressed
R3307 T4321 T4322 locationOf nuclear,translocation
R3308 T4369 T4368 themeOf PKCα,inhibition
R3309 T4325 T4324 themeOf Ser276,phosphorylation
R3310 T4372 T4373 causeOf PKCδ,phosphorylates
R3311 T4374 T4373 themeOf caspase-3,phosphorylates
R3312 T4325 T4323 partOf Ser276,p65
R3313 T4326 T4329 themeOf phosphorylation,by
R3314 T4327 T4326 themeOf Ser276,phosphorylation
R3315 T4327 T4328 partOf Ser276,p65
R3316 T4383 T4388 themeOf regulated,dependent
R3317 T4332 T4331 themeOf IκBα,stabilizing
R3318 T4384 T4383 themeOf phosphorylation,regulated
R3319 T4385 T4384 themeOf Ser276,phosphorylation
R3320 T4385 T4386 partOf Ser276,p65
R3321 T4387 T4388 causeOf M-CSF,dependent
R3322 T4333 T4334 causeOf Pim-1,phosphorylates
R3323 T4336 T4334 themeOf Ser276,phosphorylates
R3324 T4390 T4389 themeOf phosphorylation,regulated
R3325 T4391 T4390 themeOf Ser276,phosphorylation
R3326 T4391 T4392 partOf Ser276,p65
R3327 T4336 T4335 partOf Ser276,p65
R3904 T5259 T5260 causeOf M-CSF,increased
R3905 T5261 T5262 themeOf NF-κB,activity
R3906 T5262 T5260 themeOf activity,increased
R4565 T6129 T6131 themeOf PKCα,inhibitor
R4566 T6130 T6132 themeOf β,inhibitor
R4567 T6140 T6138 themeOf p65,regulated
R4568 T6141 T6139 themeOf c-Rel,regulated
R4569 T6145 T6144 themeOf c-Rel,expressing
R4570 T6147 T6146 themeOf p65,functioned
R496 T697 T696 themeOf Activating,Induces
R497 T699 T697 themeOf Phosphorylation,Activating
R498 T700 T699 themeOf Ser276,Phosphorylation
R499 T700 T698 partOf Ser276,p65
R500 T702 T701 equivalentTo M-CSF,Macrophage colony-stimulating factor
R501 T705 T707 themeOf PKCα,inhibitor
R502 T706 T708 themeOf β,inhibitor
R503 T710 T709 themeOf dominant negative PKCα,overexpression
R504 T714 T715 themeOf Ser276,phosphorylation
R505 T714 T716 partOf Ser276,p65
R506 T715 T713 themeOf phosphorylation,reduced
R507 T721 T719 themeOf induced,important
R508 T723 T724 themeOf Ser276,phosphorylation
R509 T723 T722 partOf Ser276,p65
R510 T724 T721 themeOf phosphorylation,induced
R511 T726 T725 partOf Ser276,p65
R5137 T6920 T6919 themeOf cleaved,expression
R5138 T6921 T6920 themeOf caspase-3,cleaved
R5139 T6924 T6923 themeOf M-CSF,absence
R5140 T6924 T6922 themeOf M-CSF,presence
R5141 T6925 T6928 causeOf M-CSF,elevated
R5142 T6926 T6928 themeOf cleaved,elevated
R5143 T6927 T6926 themeOf caspase-3,cleaved
R5144 T6929 T6930 causeOf M-CSF,less
R5145 T6931 T6930 themeOf cleaved,less
R5146 T6932 T6931 themeOf caspase-3,cleaved
R5147 T6937 T6938 causeOf M-CSF,reduced
R5148 T6939 T6940 themeOf Annexin V,negative
R5149 T6940 T6938 themeOf negative,reduced
R5504 T7414 T7415 themeOf PKCα,downstream target
R5505 T7416 T7415 causeOf M-CSF,downstream target
R554 T695 T696 causeOf M-CSF,Induces
R5886 T7936 T7937 themeOf p65,Activation
R5887 T7937 T7935 themeOf Activation,Regulate
R5888 T7940 T7938 themeOf IκBα,phosphorylation
R5889 T7940 T7939 themeOf IκBα,degradation
R5890 T7944 T7945 themeOf IκBα,degradation
R5891 T7945 T7946 themeOf degradation,regulated
R5892 T7948 T7947 themeOf synthesis,inhibit
R5893 T7949 T7948 themeOf IκBα,synthesis
R5894 T7951 T7952 causeOf M-CSF,induced
R5895 T7952 T7950 themeOf induced,alter
R5896 T7953 T7954 themeOf IκBα,degradation
R5897 T7954 T7952 themeOf degradation,induced
R5898 T7957 T7956 themeOf post-translational modification,augmented
R5899 T7958 T7957 themeOf p65,post-translational modification
R6929 T9202 T9203 causeOf M-CSF,influencing
R6930 T9204 T9203 themeOf IκBα,influencing
R6931 T9205 T9206 causeOf M-CSF,affected
R6932 T9207 T9208 themeOf p65,post-translational mechanisms
R6933 T9208 T9206 themeOf post-translational mechanisms,affected
R6934 T9210 T9209 themeOf p65,phosphorylation
R6935 T9214 T9213 partOf Ser276,p65
R6936 T9214 T9212 themeOf Ser276,phospho
R6937 T9215 T9213 partOf Ser536,p65
R6938 T9215 T9211 themeOf Ser536,phospho
R6939 T9216 T9217 causeOf M-CSF,induced
R6940 T9216 T9218 causeOf M-CSF,induced
R6941 T9219 T9217 themeOf phosphorylation,induced
R6942 T9220 T9218 themeOf phosphorylation,induced
R6943 T9221 T9219 themeOf Ser276,phosphorylation
R6944 T9221 T9223 partOf Ser276,p65
R6945 T9222 T9220 themeOf Ser536,phosphorylation
R6946 T9222 T9223 partOf Ser536,p65
R6947 T9226 T9227 themeOf Ser276,phosphorylation
R6948 T9226 T9223 partOf Ser276,p65
R6949 T9227 T9225 themeOf phosphorylation,reduced
R6950 T9228 T9229 themeOf Ser536,phosphorylation
R6951 T9228 T9223 partOf Ser536,p65
R6952 T9229 T9224 themeOf phosphorylation,reduced
R6953 T9231 T9232 causeOf M-CSF,stimulated
R6954 T9232 T9236 themeOf stimulated,dependent
R6955 T9234 T9232 themeOf phosphorylation,stimulated
R6956 T9235 T9234 themeOf Ser276,phosphorylation
R6957 T9235 T9233 partOf Ser276,p65
R6958 T9237 T9244 themeOf regulated,stimulation
R6959 T9238 T9245 themeOf regulated,stimulation
R6960 T9239 T9240 themeOf Ser276,phosphorylation
R6961 T9239 T9233 partOf Ser276,p65
R6962 T9240 T9237 themeOf phosphorylation,regulated
R6963 T9241 T9238 themeOf phosphorylation,regulated
R6964 T9242 T9241 themeOf Ser536,phosphorylation
R6965 T9242 T9233 partOf Ser536,p65
R6966 T9243 T9244 causeOf M-CSF,stimulation
R6967 T9243 T9245 causeOf M-CSF,stimulation
R6968 T9248 T9246 themeOf p65,location
R6969 T9248 T9247 themeOf p65,phosphorylated
R6970 T9250 T9249 themeOf p65,phosphorylated
R6971 T9250 T9251 themeOf p65,located
R6972 T9252 T9251 locationOf both cytosolic and nuclear fractions,located
R6973 T9255 T9253 themeOf Ser276,phosphorylated
R6974 T9255 T9257 partOf Ser276,p65
R6975 T9256 T9254 themeOf Ser536,phosphorylated
R6976 T9256 T9257 partOf Ser536,p65
R6977 T9257 T9258 themeOf p65,located
R6978 T9258 T9260 themeOf located,after
R6979 T9259 T9258 locationOf nuclear,located
R6980 T9261 T9260 causeOf M-CSF,after
R6981 T9263 T9262 themeOf Ser536,phosphorylation
R6982 T9263 T9264 partOf Ser536,p65
R6983 T9266 T9267 causeOf M-CSF,induced
R6984 T9267 T9265 themeOf induced,reduced
R6985 T9268 T9269 themeOf Ser276,phosphorylation
R6986 T9268 T9270 partOf Ser276,p65
R6987 T9269 T9267 themeOf phosphorylation,induced
R6988 T9271 T9272 causeOf M-CSF,induced
R6989 T9272 T9276 themeOf induced,regardless
R6990 T9274 T9275 themeOf Ser536,phosphorylation
R6991 T9274 T9273 partOf Ser536,p65
R6992 T9275 T9272 themeOf phosphorylation,induced
R6993 T9277 T9278 causeOf M-CSF,induced
R6994 T9278 T9283 themeOf induced,regulated
R6995 T9279 T9282 themeOf induced,regulated
R6996 T9280 T9278 themeOf Ser276,induced
R6997 T9280 T9273 partOf Ser276,p65
R6998 T9281 T9279 themeOf Ser536,induced
R6999 T9281 T9273 partOf Ser536,p65
R7519 T9985 T9986 themeOf IκBα,induced
R7520 T9990 T9991 causeOf M-CSF,enhanced
R7521 T9992 T9993 themeOf IκBα,expression
R7522 T9993 T9991 themeOf expression,enhanced
R7523 T9995 T9996 themeOf IκBα,expression
R7524 T9996 T9994 themeOf expression,decreased
R7525 T9999 T10000 themeOf BCL-xL,regulated
R7526 T9999 T9998 themeOf BCL-xL,expression
R7527 T10003 T10001 themeOf stimulated,reduced
R7528 T10004 T10005 themeOf BCL-xL,expression
R7529 T10005 T10003 themeOf expression,stimulated
R8927 T11959 T11961 themeOf PKCα,inhibitors
R8928 T11960 T11962 themeOf β,inhibitors
R8929 T11967 T11970 themeOf PKCα,co-transfected
R8930 T11969 T11968 themeOf PKCα,kinase-deficient
R8931 T11972 T11971 themeOf PKCα,co-transfected
R8932 T11973 T11974 themeOf M-CSF,activation
R8933 T11977 T11976 themeOf PKCα,KD
R8934 T11979 T11980 themeOf PKCα,transfected
R8935 T11982 T11981 themeOf PKCα,transfected
R8936 T11983 T11984 themeOf M-CSF,activation
R8937 T11986 T11985 themeOf PKCα,transfected
R8938 T11988 T11987 themeOf PKCα,KD
R8939 T11991 T11990 themeOf PKCα,transfected
R8940 T11993 T11992 themeOf PKCα,expressing
R8941 T11995 T11994 themeOf PKCα,KD
R8942 T11998 T11999 themeOf Annexin V,negative
R8943 T12001 T12000 themeOf PKCα,expression
R8944 T12003 T12002 themeOf PKCα,KD
R8945 T12006 T12005 themeOf PKCα,expressing
R8946 T12007 T12009 causeOf KD,affect
R8947 T12007 T12013 causeOf KD,attenuated
R8948 T12008 T12007 themeOf PKCα,KD
R8949 T12010 T12009 themeOf phosphorylation,affect
R8950 T12011 T12010 themeOf Ser536,phosphorylation
R8951 T12011 T12012 partOf Ser536,p65
R8952 T12011 T12020 themeOf Ser536,phosphorylation
R8953 T12014 T12013 themeOf phosphorylation,attenuated
R8954 T12015 T12014 themeOf Ser276,phosphorylation
R8955 T12015 T12012 partOf Ser276,p65
R8956 T12015 T12021 themeOf Ser276,phosphorylation
R8957 T12016 T12018 causeOf Expression,effect
R8958 T12016 T12019 causeOf Expression,effect
R8959 T12017 T12016 themeOf PKCα,Expression
R8960 T12018 T12022 themeOf effect,with or without
R8961 T12019 T12023 themeOf effect,with or without
R8962 T12020 T12018 themeOf phosphorylation,effect
R8963 T12021 T12019 themeOf phosphorylation,effect
R8964 T12024 T12023 causeOf M-CSF,with or without
R8965 T12024 T12022 causeOf M-CSF,with or without
R8966 T12028 T12027 themeOf Ser276,phosphorylation
R8967 T12028 T12029 partOf Ser276,p65
R8968 T12036 T12035 themeOf M-CSF,absence
R8969 T12036 T12034 themeOf M-CSF,presence
R8970 T12038 T12039 themeOf PKCα,expression
R8971 T12039 T12037 themeOf expression,Reducing
R8972 T12045 T12046 causeOf PKCα siRNA,decreased
R8973 T12047 T12048 themeOf PKCα,expression
R8974 T12048 T12046 themeOf expression,decreased