| Id |
Subject |
Object |
Predicate |
Lexical cue |
Negation |
Speculation |
| T2369 |
459-468 |
Regulation |
denotes |
regulator |
|
|
| T2370 |
472-495 |
Protein |
denotes |
tumor necrosis factor-α |
|
|
| T2371 |
497-502 |
Protein |
denotes |
TNF-α |
|
|
| T2372 |
504-514 |
Gene_expression |
denotes |
production |
|
|
| T2373 |
517-522 |
Protein |
denotes |
TNF-α |
|
|
| T2374 |
625-630 |
Protein |
denotes |
TNF-α |
|
|
| T2375 |
631-640 |
Gene_expression |
denotes |
synthesis |
|
|
| T2376 |
648-658 |
Negative_regulation |
denotes |
attenuated |
|
|
| T2377 |
853-857 |
Positive_regulation |
denotes |
lead |
|
|
| T2378 |
865-879 |
Negative_regulation |
denotes |
downregulation |
|
|
| T2379 |
883-888 |
Protein |
denotes |
TNF-α |
|
|
| T2380 |
889-899 |
Gene_expression |
denotes |
production |
|
|
| T2381 |
1927-1934 |
Negative_regulation |
denotes |
inhibit |
|
|
| T2382 |
1941-1950 |
Regulation |
denotes |
dependent |
|
|
| T2383 |
1973-1986 |
Transcription |
denotes |
transcription |
|
|
| T2384 |
2008-2013 |
Protein |
denotes |
TNF-α |
|
|
| T2385 |
2097-2111 |
Negative_regulation |
denotes |
down-regulates |
|
|
| T2386 |
2112-2117 |
Protein |
denotes |
TNF-α |
|
|
| T2387 |
2118-2128 |
Gene_expression |
denotes |
production |
|
|
| T2388 |
2776-2780 |
Regulation |
denotes |
role |
|
true |
| T2389 |
2795-2802 |
Positive_regulation |
denotes |
induced |
|
|
| T2390 |
2803-2808 |
Protein |
denotes |
TNF-α |
|
|
| T2391 |
2809-2819 |
Gene_expression |
denotes |
production |
|
|
| T3205 |
3568-3582 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T3206 |
3583-3587 |
Protein |
denotes |
CREB |
|
|
| T3207 |
3589-3599 |
Entity |
denotes |
serine 133 |
|
|
| T3208 |
3602-3616 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T3209 |
3602-3616 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T3210 |
3617-3622 |
Protein |
denotes |
I-κBα |
|
|
| T3211 |
3624-3634 |
Entity |
denotes |
serines 32 |
|
|
| T3212 |
3639-3641 |
Entity |
denotes |
36 |
|
|
| T3213 |
3644-3658 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T3214 |
3665-3668 |
Protein |
denotes |
p65 |
|
|
| T3215 |
3678-3688 |
Entity |
denotes |
serine 276 |
|
|
| T3216 |
3913-3918 |
Protein |
denotes |
TNF-α |
|
|
| T3941 |
6118-6125 |
Positive_regulation |
denotes |
induced |
|
|
| T3942 |
6126-6131 |
Protein |
denotes |
TNF-α |
|
|
| T3943 |
6132-6142 |
Gene_expression |
denotes |
production |
|
|
| T3944 |
6295-6308 |
Positive_regulation |
denotes |
up-regulation |
|
|
| T3945 |
6313-6328 |
Negative_regulation |
denotes |
down-regulation |
|
|
| T3946 |
6332-6337 |
Protein |
denotes |
TNF-α |
|
|
| T3947 |
6338-6348 |
Gene_expression |
denotes |
production |
|
|
| T4106 |
6427-6434 |
Positive_regulation |
denotes |
induced |
|
|
| T4107 |
6435-6440 |
Protein |
denotes |
TNF-α |
|
|
| T4108 |
6441-6451 |
Gene_expression |
denotes |
production |
|
|
| T4109 |
6494-6499 |
Protein |
denotes |
TNF-α |
|
|
| T4881 |
6741-6746 |
Protein |
denotes |
I-κBα |
|
|
| T4882 |
6754-6757 |
Protein |
denotes |
p65 |
|
|
| T4883 |
6763-6767 |
Protein |
denotes |
CREB |
|
|
| T4884 |
7730-7744 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T4885 |
7745-7750 |
Protein |
denotes |
I-κBα |
|
|
| T4886 |
7819-7833 |
Phosphorylation |
denotes |
phosphorylated |
|
|
| T4887 |
7840-7843 |
Protein |
denotes |
p65 |
|
|
| T6040 |
10429-10433 |
Regulation |
denotes |
Role |
|
|
| T6041 |
10448-10455 |
Positive_regulation |
denotes |
induced |
|
|
| T6042 |
10473-10478 |
Protein |
denotes |
TNF-α |
|
|
| T6043 |
10479-10489 |
Gene_expression |
denotes |
production |
|
|
| T6044 |
10506-10510 |
Regulation |
denotes |
role |
|
|
| T6045 |
10521-10526 |
Protein |
denotes |
TNF-α |
|
|
| T6046 |
10527-10537 |
Gene_expression |
denotes |
production |
|
|
| T6047 |
10567-10578 |
Regulation |
denotes |
involvement |
|
|
| T6048 |
10586-10597 |
Negative_regulation |
denotes |
attenuation |
|
|
| T6049 |
10605-10612 |
Positive_regulation |
denotes |
induced |
|
|
| T6050 |
10613-10618 |
Protein |
denotes |
TNF-α |
|
|
| T6051 |
10619-10629 |
Gene_expression |
denotes |
production |
|
|
| T6052 |
11205-11210 |
Protein |
denotes |
TNF-α |
|
|
| T6411 |
11760-11767 |
Regulation |
denotes |
effects |
|
true |
| T6412 |
11782-11789 |
Positive_regulation |
denotes |
induced |
|
|
| T6413 |
11790-11795 |
Protein |
denotes |
TNF-α |
|
|
| T6414 |
11796-11806 |
Gene_expression |
denotes |
production |
|
|
| T6415 |
11854-11859 |
Protein |
denotes |
TNF-α |
|
|
| T6416 |
11860-11870 |
Gene_expression |
denotes |
production |
|
|
| T6417 |
11881-11892 |
Positive_regulation |
denotes |
stimulation |
|
|
| T6418 |
11991-11997 |
Regulation |
denotes |
effect |
|
|
| T6419 |
12001-12006 |
Protein |
denotes |
TNF-α |
|
|
| T6420 |
12007-12017 |
Gene_expression |
denotes |
production |
|
|
| T6929 |
12105-12110 |
Positive_regulation |
denotes |
leads |
|
|
| T6930 |
12133-12144 |
Protein_catabolism |
denotes |
degradation |
|
|
| T6931 |
12148-12153 |
Protein |
denotes |
I-κBα |
|
|
| T6932 |
12223-12230 |
Regulation |
denotes |
effects |
|
true |
| T6933 |
12241-12246 |
Protein |
denotes |
I-κBα |
|
|
| T6934 |
12260-12265 |
Protein |
denotes |
I-κBα |
|
|
| T6935 |
12266-12281 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T6936 |
12295-12304 |
Positive_regulation |
denotes |
increased |
|
|
| T6937 |
12305-12314 |
Positive_regulation |
denotes |
following |
|
|
| T6938 |
12423-12436 |
Negative_regulation |
denotes |
downregulated |
|
|
| T6939 |
12441-12448 |
Positive_regulation |
denotes |
induced |
|
|
| T6940 |
12449-12454 |
Protein |
denotes |
I-κBα |
|
|
| T6941 |
12455-12470 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T6942 |
12528-12531 |
Protein |
denotes |
p65 |
|
|
| T6943 |
12532-12547 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T6944 |
12552-12561 |
Positive_regulation |
denotes |
increased |
|
|
| T6945 |
12562-12571 |
Positive_regulation |
denotes |
following |
|
|
| T6946 |
12635-12644 |
Negative_regulation |
denotes |
decreased |
|
|
| T6947 |
12649-12656 |
Positive_regulation |
denotes |
induced |
|
|
| T6948 |
12663-12666 |
Protein |
denotes |
p65 |
|
|
| T6949 |
12675-12690 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T7544 |
14015-14024 |
Positive_regulation |
denotes |
increased |
|
|
| T7545 |
14025-14029 |
Protein |
denotes |
CREB |
|
|
| T7546 |
14034-14041 |
Binding |
denotes |
binding |
|
|
| T7957 |
14078-14084 |
Regulation |
denotes |
Effect |
|
true |
| T7958 |
14095-14100 |
Protein |
denotes |
TNF-α |
|
|
| T7959 |
14101-14111 |
Gene_expression |
denotes |
production |
|
|
| T7960 |
14112-14130 |
Regulation |
denotes |
in the presence of |
|
|
| T7961 |
14150-14154 |
Regulation |
denotes |
role |
|
|
| T7962 |
14169-14176 |
Positive_regulation |
denotes |
induced |
|
|
| T7963 |
14177-14191 |
Negative_regulation |
denotes |
downregulation |
|
|
| T7964 |
14195-14200 |
Protein |
denotes |
TNF-α |
|
|
| T7965 |
14201-14211 |
Gene_expression |
denotes |
production |
|
|
| T7966 |
14390-14398 |
Positive_regulation |
denotes |
resulted |
|
|
| T7967 |
14404-14413 |
Negative_regulation |
denotes |
reduction |
|
|
| T7968 |
14417-14422 |
Protein |
denotes |
TNF-α |
|
|
| T7969 |
14595-14601 |
Regulation |
denotes |
result |
true |
|
| T7970 |
14621-14631 |
Regulation |
denotes |
modulation |
|
|
| T7971 |
14635-14640 |
Protein |
denotes |
TNF-α |
|
|
| T7972 |
14641-14651 |
Gene_expression |
denotes |
production |
|
|
| T7973 |
14750-14764 |
Negative_regulation |
denotes |
downregulation |
|
|
| T7974 |
14768-14773 |
Protein |
denotes |
TNF-α |
|
|
| T7975 |
14774-14784 |
Gene_expression |
denotes |
production |
|
|
| T7976 |
14854-14865 |
Regulation |
denotes |
independent |
true |
|
| T10083 |
15099-15104 |
Protein |
denotes |
TNF-α |
|
|
| T10084 |
15108-15116 |
Localization |
denotes |
released |
|
|
| T10085 |
15128-15137 |
Positive_regulation |
denotes |
following |
|
|
| T10086 |
15329-15338 |
Positive_regulation |
denotes |
increased |
|
|
| T10087 |
15339-15344 |
Protein |
denotes |
TNF-α |
|
|
| T10088 |
15345-15354 |
Gene_expression |
denotes |
synthesis |
|
|
| T10089 |
15574-15584 |
Negative_regulation |
denotes |
decreasing |
|
|
| T10090 |
15585-15590 |
Protein |
denotes |
TNF-α |
|
|
| T10091 |
15601-15612 |
Negative_regulation |
denotes |
attenuating |
|
|
| T10092 |
15617-15627 |
Gene_expression |
denotes |
production |
|
|
| T10093 |
15679-15691 |
Negative_regulation |
denotes |
downregulate |
|
|
| T10094 |
15692-15697 |
Protein |
denotes |
TNF-α |
|
|
| T10095 |
15698-15708 |
Gene_expression |
denotes |
production |
|
|
| T10096 |
15788-15793 |
Protein |
denotes |
TNF-α |
|
|
| T10097 |
15813-15821 |
Positive_regulation |
denotes |
increase |
|
|
| T10098 |
15916-15924 |
Negative_regulation |
denotes |
decrease |
|
|
| T10099 |
15925-15930 |
Protein |
denotes |
TNF-α |
|
|
| T10100 |
15994-16005 |
Negative_regulation |
denotes |
attenuation |
|
|
| T10101 |
16013-16020 |
Positive_regulation |
denotes |
induced |
|
|
| T10102 |
16021-16026 |
Protein |
denotes |
TNF-α |
|
|
| T10103 |
16027-16037 |
Gene_expression |
denotes |
expression |
|
|
| T10104 |
16202-16211 |
Negative_regulation |
denotes |
decreases |
|
true |
| T10105 |
16212-16217 |
Protein |
denotes |
TNF-α |
|
|
| T10106 |
16218-16228 |
Gene_expression |
denotes |
production |
|
|
| T10107 |
16675-16686 |
Negative_regulation |
denotes |
attenuation |
|
|
| T10108 |
16690-16695 |
Protein |
denotes |
TNF-α |
|
|
| T10585 |
16696-16706 |
Gene_expression |
denotes |
production |
|
|
| T10586 |
16749-16758 |
Positive_regulation |
denotes |
following |
|
|
| T10587 |
16779-16790 |
Regulation |
denotes |
independent |
true |
|
| T10588 |
17206-17213 |
Regulation |
denotes |
effects |
|
|
| T10589 |
17217-17222 |
Protein |
denotes |
TNF-α |
|
|
| T10590 |
17223-17232 |
Gene_expression |
denotes |
synthesis |
|
|
| T10591 |
17310-17324 |
Negative_regulation |
denotes |
downregulation |
|
|
| T10592 |
17328-17333 |
Protein |
denotes |
TNF-α |
|
|
| T10593 |
17939-17942 |
Protein |
denotes |
p50 |
|
|
| T10594 |
17943-17946 |
Protein |
denotes |
p65 |
|
|
| T10595 |
18055-18060 |
Protein |
denotes |
I-κBα |
|
|
| T10596 |
18223-18228 |
Protein |
denotes |
IKK-1 |
|
|
| T10597 |
18233-18238 |
Protein |
denotes |
IKK-2 |
|
|
| T10598 |
18254-18268 |
Phosphorylation |
denotes |
phosphorylates |
|
|
| T10599 |
18273-18278 |
Protein |
denotes |
I-κBα |
|
|
| T10600 |
18288-18303 |
Phosphorylation |
denotes |
Phosphorylation |
|
|
| T10601 |
18305-18319 |
Ubiquitination |
denotes |
ubiquitination |
|
|
| T10602 |
18336-18347 |
Protein_catabolism |
denotes |
degradation |
|
|
| T10603 |
18351-18356 |
Protein |
denotes |
I-κBα |
|
|
| T10604 |
18617-18622 |
Protein |
denotes |
TNF-α |
|
|
| T10605 |
18689-18697 |
Regulation |
denotes |
involved |
|
true |
| T10606 |
18701-18706 |
Protein |
denotes |
TNF-α |
|
|
| T10607 |
18707-18722 |
Gene_expression |
denotes |
gene expression |
|
|
| T10608 |
18804-18817 |
Negative_regulation |
denotes |
downregulates |
|
|
| T10609 |
18804-18817 |
Negative_regulation |
denotes |
downregulates |
|
|
| T10610 |
18804-18817 |
Negative_regulation |
denotes |
downregulates |
|
|
| T10611 |
18830-18835 |
Protein |
denotes |
I-κBα |
|
|
| T10612 |
18836-18851 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T10613 |
18867-18870 |
Protein |
denotes |
p65 |
|
|
| T10614 |
18871-18886 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T10615 |
18887-18900 |
Localization |
denotes |
translocation |
|
|
| T10616 |
19025-19030 |
Protein |
denotes |
I-κBα |
|
|
| T10617 |
19031-19046 |
Phosphorylation |
denotes |
phosphorylation |
|
|
| T10618 |
19089-19096 |
Regulation |
denotes |
effects |
|
|
| T10619 |
19124-19129 |
Protein |
denotes |
I-κBα |
|
|
| T10620 |
19242-19249 |
Regulation |
denotes |
effects |
|
|
| T10621 |
19260-19265 |
Protein |
denotes |
I-κBα |
|
|
| T10622 |
19379-19389 |
Regulation |
denotes |
stabilizes |
|
|
| T10623 |
19394-19405 |
Binding |
denotes |
interaction |
|
|
| T10624 |
19414-19419 |
Protein |
denotes |
I-κBα |
|
|
| T10625 |
19524-19529 |
Protein |
denotes |
I-κBα |
|
|
| T10626 |
19530-19541 |
Protein_catabolism |
denotes |
degradation |
|
|
| T10627 |
19573-19581 |
Regulation |
denotes |
presence |
|
|
| T10628 |
19586-19593 |
Regulation |
denotes |
absence |
true |
|
| T10629 |
19805-19808 |
Protein |
denotes |
p65 |
|
|
| T10630 |
20329-20340 |
Negative_regulation |
denotes |
attenuation |
|
|
| T10631 |
20348-20355 |
Positive_regulation |
denotes |
induced |
|
|
| T10632 |
20356-20361 |
Protein |
denotes |
TNF-α |
|
|
| T10633 |
20362-20372 |
Gene_expression |
denotes |
production |
|
|
| T10634 |
20387-20406 |
Regulation |
denotes |
presence or absence |
true |
|
| T10635 |
21404-21407 |
Protein |
denotes |
CBP |
|
|
| T10636 |
21426-21430 |
Protein |
denotes |
p300 |
|
|
| T10637 |
21679-21684 |
Protein |
denotes |
c-fos |
|
|
| T10638 |
21690-21695 |
Protein |
denotes |
c-jun |
|
|
| T10639 |
21737-21747 |
Positive_regulation |
denotes |
Activation |
|
|
| T10640 |
21737-21747 |
Positive_regulation |
denotes |
Activation |
|
|
| T10641 |
21776-21781 |
Protein |
denotes |
c-fos |
|
|
| T10642 |
21786-21791 |
Protein |
denotes |
c-jun |
|
|
| T10643 |
21851-21861 |
Regulation |
denotes |
implicated |
|
|
| T10644 |
21865-21870 |
Protein |
denotes |
TNF-α |
|
|
| T10645 |
21871-21881 |
Gene_expression |
denotes |
expression |
|
|
| T10646 |
21907-21916 |
Binding |
denotes |
recognize |
|
|
| T10647 |
21927-21947 |
Entity |
denotes |
DNA binding sequence |
|
|
| T10648 |
21978-21983 |
Protein |
denotes |
TNF-α |
|
|
| T10649 |
22155-22165 |
Negative_regulation |
denotes |
inhibiting |
|
|
| T10650 |
22166-22171 |
Protein |
denotes |
TNF-α |
|
|
| T10651 |
22177-22190 |
Transcription |
denotes |
transcription |
|
|
| T10652 |
22553-22566 |
Negative_regulation |
denotes |
downregulates |
|
|
| T10653 |
22567-22572 |
Protein |
denotes |
TNF-α |
|
|
| T10654 |
22573-22583 |
Gene_expression |
denotes |
production |
|
|
| T10655 |
22617-22628 |
Regulation |
denotes |
independent |
true |
|
| T10656 |
22919-22924 |
Protein |
denotes |
TNF-α |
|
|
| T10657 |
22925-22935 |
Gene_expression |
denotes |
production |
|
|
| R1831 |
T2370 |
T2372 |
themeOf |
tumor necrosis factor-α,production |
| R1832 |
T2371 |
T2370 |
equivalentTo |
TNF-α,tumor necrosis factor-α |
| R1833 |
T2372 |
T2369 |
themeOf |
production,regulator |
| R1834 |
T2374 |
T2375 |
themeOf |
TNF-α,synthesis |
| R1836 |
T2375 |
T2376 |
themeOf |
synthesis,attenuated |
| R1838 |
T2378 |
T2377 |
themeOf |
downregulation,lead |
| R1839 |
T2379 |
T2380 |
themeOf |
TNF-α,production |
| R1840 |
T2380 |
T2378 |
themeOf |
production,downregulation |
| R1842 |
T2382 |
T2381 |
themeOf |
dependent,inhibit |
| R1843 |
T2383 |
T2382 |
themeOf |
transcription,dependent |
| R1845 |
T2384 |
T2383 |
themeOf |
TNF-α,transcription |
| R1846 |
T2386 |
T2387 |
themeOf |
TNF-α,production |
| R1848 |
T2387 |
T2385 |
themeOf |
production,down-regulates |
| R1849 |
T2389 |
T2388 |
themeOf |
induced,role |
| R1850 |
T2390 |
T2391 |
themeOf |
TNF-α,production |
| R1853 |
T2391 |
T2389 |
themeOf |
production,induced |
| R2569 |
T3207 |
T3205 |
themeOf |
serine 133,phosphorylated |
| R2570 |
T3207 |
T3206 |
partOf |
serine 133,CREB |
| R2571 |
T3211 |
T3209 |
themeOf |
serines 32,phosphorylated |
| R2572 |
T3211 |
T3210 |
partOf |
serines 32,I-κBα |
| R2573 |
T3212 |
T3208 |
themeOf |
36,phosphorylated |
| R2574 |
T3212 |
T3210 |
partOf |
36,I-κBα |
| R2575 |
T3215 |
T3213 |
themeOf |
serine 276,phosphorylated |
| R2576 |
T3215 |
T3214 |
partOf |
serine 276,p65 |
| R3234 |
T3942 |
T3943 |
themeOf |
TNF-α,production |
| R3235 |
T3943 |
T3941 |
themeOf |
production,induced |
| R3236 |
T3946 |
T3947 |
themeOf |
TNF-α,production |
| R3237 |
T3947 |
T3944 |
themeOf |
production,up-regulation |
| R3238 |
T3947 |
T3945 |
themeOf |
production,down-regulation |
| R3363 |
T4107 |
T4108 |
themeOf |
TNF-α,production |
| R3364 |
T4108 |
T4106 |
themeOf |
production,induced |
| R4030 |
T4885 |
T4884 |
themeOf |
I-κBα,phosphorylated |
| R4031 |
T4887 |
T4886 |
themeOf |
p65,phosphorylated |
| R5017 |
T6041 |
T6040 |
themeOf |
induced,Role |
| R5018 |
T6042 |
T6043 |
themeOf |
TNF-α,production |
| R5019 |
T6043 |
T6041 |
themeOf |
production,induced |
| R5020 |
T6045 |
T6046 |
themeOf |
TNF-α,production |
| R5021 |
T6046 |
T6044 |
themeOf |
production,role |
| R5022 |
T6048 |
T6047 |
themeOf |
attenuation,involvement |
| R5023 |
T6049 |
T6048 |
themeOf |
induced,attenuation |
| R5024 |
T6050 |
T6051 |
themeOf |
TNF-α,production |
| R5025 |
T6051 |
T6049 |
themeOf |
production,induced |
| R5320 |
T6412 |
T6411 |
themeOf |
induced,effects |
| R5321 |
T6413 |
T6414 |
themeOf |
TNF-α,production |
| R5322 |
T6414 |
T6412 |
themeOf |
production,induced |
| R5323 |
T6415 |
T6416 |
themeOf |
TNF-α,production |
| R5324 |
T6416 |
T6417 |
themeOf |
production,stimulation |
| R5325 |
T6419 |
T6420 |
themeOf |
TNF-α,production |
| R5326 |
T6420 |
T6418 |
themeOf |
production,effect |
| R5767 |
T6930 |
T6929 |
themeOf |
degradation,leads |
| R5768 |
T6931 |
T6930 |
themeOf |
I-κBα,degradation |
| R5769 |
T6933 |
T6932 |
themeOf |
I-κBα,effects |
| R5770 |
T6934 |
T6935 |
themeOf |
I-κBα,phosphorylation |
| R5771 |
T6935 |
T6936 |
themeOf |
phosphorylation,increased |
| R5772 |
T6936 |
T6937 |
themeOf |
increased,following |
| R5773 |
T6939 |
T6938 |
themeOf |
induced,downregulated |
| R5774 |
T6940 |
T6941 |
themeOf |
I-κBα,phosphorylation |
| R5775 |
T6941 |
T6939 |
themeOf |
phosphorylation,induced |
| R5776 |
T6942 |
T6943 |
themeOf |
p65,phosphorylation |
| R5777 |
T6943 |
T6944 |
themeOf |
phosphorylation,increased |
| R5778 |
T6944 |
T6945 |
themeOf |
increased,following |
| R5779 |
T6947 |
T6946 |
themeOf |
induced,decreased |
| R5780 |
T6948 |
T6949 |
themeOf |
p65,phosphorylation |
| R5781 |
T6949 |
T6947 |
themeOf |
phosphorylation,induced |
| R6228 |
T7545 |
T7546 |
themeOf |
CREB,binding |
| R6229 |
T7546 |
T7544 |
themeOf |
binding,increased |
| R6571 |
T7957 |
T7960 |
themeOf |
Effect,in the presence of |
| R6572 |
T7958 |
T7959 |
themeOf |
TNF-α,production |
| R6573 |
T7959 |
T7957 |
themeOf |
production,Effect |
| R6574 |
T7962 |
T7961 |
themeOf |
induced,role |
| R6575 |
T7963 |
T7962 |
themeOf |
downregulation,induced |
| R6576 |
T7964 |
T7965 |
themeOf |
TNF-α,production |
| R6577 |
T7965 |
T7963 |
themeOf |
production,downregulation |
| R6578 |
T7967 |
T7966 |
themeOf |
reduction,resulted |
| R6579 |
T7968 |
T7967 |
themeOf |
TNF-α,reduction |
| R6580 |
T7970 |
T7969 |
themeOf |
modulation,result |
| R6581 |
T7971 |
T7972 |
themeOf |
TNF-α,production |
| R6582 |
T7972 |
T7970 |
themeOf |
production,modulation |
| R6583 |
T7973 |
T7976 |
themeOf |
downregulation,independent |
| R6584 |
T7974 |
T7975 |
themeOf |
TNF-α,production |
| R6585 |
T7975 |
T7973 |
themeOf |
production,downregulation |
| R8182 |
T10083 |
T10084 |
themeOf |
TNF-α,released |
| R8183 |
T10084 |
T10085 |
themeOf |
released,following |
| R8184 |
T10087 |
T10088 |
themeOf |
TNF-α,synthesis |
| R8185 |
T10088 |
T10086 |
themeOf |
synthesis,increased |
| R8186 |
T10090 |
T10092 |
themeOf |
TNF-α,production |
| R8187 |
T10090 |
T10089 |
themeOf |
TNF-α,decreasing |
| R8188 |
T10092 |
T10091 |
themeOf |
production,attenuating |
| R8189 |
T10094 |
T10095 |
themeOf |
TNF-α,production |
| R8190 |
T10095 |
T10093 |
themeOf |
production,downregulate |
| R8191 |
T10096 |
T10097 |
themeOf |
TNF-α,increase |
| R8192 |
T10099 |
T10098 |
themeOf |
TNF-α,decrease |
| R8193 |
T10101 |
T10100 |
themeOf |
induced,attenuation |
| R8194 |
T10102 |
T10103 |
themeOf |
TNF-α,expression |
| R8195 |
T10103 |
T10101 |
themeOf |
expression,induced |
| R8196 |
T10105 |
T10106 |
themeOf |
TNF-α,production |
| R8197 |
T10106 |
T10104 |
themeOf |
production,decreases |
| R8198 |
T10107 |
T10586 |
themeOf |
attenuation,following |
| R8199 |
T10107 |
T10587 |
themeOf |
attenuation,independent |
| R8200 |
T10108 |
T10585 |
themeOf |
TNF-α,production |
| R8432 |
T10585 |
T10107 |
themeOf |
production,attenuation |
| R8437 |
T10589 |
T10590 |
themeOf |
TNF-α,synthesis |
| R8442 |
T10590 |
T10588 |
themeOf |
synthesis,effects |
| R8448 |
T10592 |
T10591 |
themeOf |
TNF-α,downregulation |
| R8450 |
T10599 |
T10598 |
themeOf |
I-κBα,phosphorylates |
| R8457 |
T10603 |
T10600 |
themeOf |
I-κBα,Phosphorylation |
| R8462 |
T10603 |
T10601 |
themeOf |
I-κBα,ubiquitination |
| R8463 |
T10603 |
T10602 |
themeOf |
I-κBα,degradation |
| R8464 |
T10606 |
T10607 |
themeOf |
TNF-α,gene expression |
| R8467 |
T10607 |
T10605 |
themeOf |
gene expression,involved |
| R8470 |
T10611 |
T10612 |
themeOf |
I-κBα,phosphorylation |
| R8477 |
T10612 |
T10609 |
themeOf |
phosphorylation,downregulates |
| R8479 |
T10613 |
T10614 |
themeOf |
p65,phosphorylation |
| R8480 |
T10613 |
T10615 |
themeOf |
p65,translocation |
| R8481 |
T10614 |
T10608 |
themeOf |
phosphorylation,downregulates |
| R8482 |
T10615 |
T10610 |
themeOf |
translocation,downregulates |
| R8483 |
T10616 |
T10617 |
themeOf |
I-κBα,phosphorylation |
| R8484 |
T10619 |
T10618 |
themeOf |
I-κBα,effects |
| R8485 |
T10621 |
T10620 |
themeOf |
I-κBα,effects |
| R8487 |
T10623 |
T10622 |
themeOf |
interaction,stabilizes |
| R8488 |
T10624 |
T10623 |
themeOf |
I-κBα,interaction |
| R8489 |
T10625 |
T10626 |
themeOf |
I-κBα,degradation |
| R8490 |
T10626 |
T10627 |
themeOf |
degradation,presence |
| R8491 |
T10626 |
T10628 |
themeOf |
degradation,absence |
| R8493 |
T10630 |
T10634 |
themeOf |
attenuation,presence or absence |
| R8494 |
T10631 |
T10630 |
themeOf |
induced,attenuation |
| R8495 |
T10632 |
T10633 |
themeOf |
TNF-α,production |
| R8496 |
T10633 |
T10631 |
themeOf |
production,induced |
| R8499 |
T10641 |
T10639 |
themeOf |
c-fos,Activation |
| R8501 |
T10642 |
T10640 |
themeOf |
c-jun,Activation |
| R8502 |
T10644 |
T10645 |
themeOf |
TNF-α,expression |
| R8504 |
T10645 |
T10643 |
themeOf |
expression,implicated |
| R8506 |
T10647 |
T10646 |
themeOf |
DNA binding sequence,recognize |
| R8508 |
T10647 |
T10648 |
partOf |
DNA binding sequence,TNF-α |
| R8512 |
T10650 |
T10651 |
themeOf |
TNF-α,transcription |
| R8513 |
T10651 |
T10649 |
themeOf |
transcription,inhibiting |
| R8515 |
T10652 |
T10655 |
themeOf |
downregulates,independent |
| R8516 |
T10653 |
T10654 |
themeOf |
TNF-α,production |
| R8517 |
T10654 |
T10652 |
themeOf |
production,downregulates |
| R8519 |
T10656 |
T10657 |
themeOf |
TNF-α,production |