craft-sa-dev Home  

PMC:88885 / 12847-13980 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T3254 0-13 RB denotes Interestingly
T3256 13-15 , denotes ,
T3257 15-18 DT denotes the
T3259 19-25 JJ denotes second
T3260 26-32 NN denotes Mcoln1
T3258 33-40 NN denotes isoform
T3261 41-43 VBZ denotes is
T3262 44-47 RB denotes not
T3255 48-52 VBN denotes seen
T3263 53-55 IN denotes in
T3264 56-62 NNS denotes humans
T3265 63-66 CC denotes and
T3266 67-70 DT denotes the
T3267 71-79 NN denotes sequence
T3269 80-82 IN denotes of
T3270 83-86 DT denotes the
T3272 87-100 RB denotes alternatively
T3273 101-108 VBN denotes spliced
T3271 109-115 NN denotes region
T3274 116-118 VBZ denotes is
T3275 119-122 RB denotes not
T3268 123-132 VBN denotes conserved
T3276 133-140 IN denotes between
T3277 141-144 NN denotes man
T3278 145-148 CC denotes and
T3279 149-154 NN denotes mouse
T3280 154-155 . denotes .
T3281 155-254 sentence denotes To date, very few genes have been reported that show species specific alternative splice variants.
T3282 156-158 IN denotes To
T3284 159-163 NN denotes date
T3285 163-165 , denotes ,
T3286 165-169 RB denotes very
T3287 170-173 JJ denotes few
T3288 174-179 NNS denotes genes
T3289 180-184 VBP denotes have
T3290 185-189 VBN denotes been
T3283 190-198 VBN denotes reported
T3291 199-203 WDT denotes that
T3292 204-208 VBP denotes show
T3293 209-216 NN denotes species
T3294 217-225 JJ denotes specific
T3296 226-237 JJ denotes alternative
T3297 238-244 NN denotes splice
T3295 245-253 NNS denotes variants
T3298 253-254 . denotes .
T3299 254-374 sentence denotes MOG, myelin/oligodendrocyte glycoprotein, has many different splice variants in humans that are not found in mice [17].
T3300 255-258 NN denotes MOG
T3302 258-260 , denotes ,
T3303 260-266 NN denotes myelin
T3305 266-267 HYPH denotes /
T3304 267-282 NN denotes oligodendrocyte
T3306 283-295 NN denotes glycoprotein
T3307 295-297 , denotes ,
T3301 297-300 VBZ denotes has
T3308 301-305 JJ denotes many
T3310 306-315 JJ denotes different
T3311 316-322 NN denotes splice
T3309 323-331 NNS denotes variants
T3312 332-334 IN denotes in
T3313 335-341 NNS denotes humans
T3314 342-346 WDT denotes that
T3316 347-350 VBP denotes are
T3317 351-354 RB denotes not
T3315 355-360 VBN denotes found
T3318 361-363 IN denotes in
T3319 364-368 NNS denotes mice
T3320 369-370 -LRB- denotes [
T3321 370-372 CD denotes 17
T3322 372-373 -RRB- denotes ]
T3323 373-374 . denotes .
T3324 374-543 sentence denotes ATP11B, a P-type ATPase, has a rabbit-specific splice variant that deletes a transmembrane domain and therefore likely alters the putative function of the protein [18].
T3325 375-381 NN denotes ATP11B
T3327 381-383 , denotes ,
T3328 383-384 DT denotes a
T3330 385-386 NN denotes P
T3332 386-387 HYPH denotes -
T3331 387-391 NN denotes type
T3329 392-398 NN denotes ATPase
T3333 398-400 , denotes ,
T3326 400-403 VBZ denotes has
T3334 404-405 DT denotes a
T3336 406-412 NN denotes rabbit
T3338 412-413 HYPH denotes -
T3337 413-421 JJ denotes specific
T3339 422-428 NN denotes splice
T3335 429-436 NN denotes variant
T3340 437-441 WDT denotes that
T3341 442-449 VBZ denotes deletes
T3342 450-451 DT denotes a
T3344 452-465 JJ denotes transmembrane
T3343 466-472 NN denotes domain
T3345 473-476 CC denotes and
T3346 477-486 RB denotes therefore
T3348 487-493 RB denotes likely
T3347 494-500 VBZ denotes alters
T3349 501-504 DT denotes the
T3351 505-513 JJ denotes putative
T3350 514-522 NN denotes function
T3352 523-525 IN denotes of
T3353 526-529 DT denotes the
T3354 530-537 NN denotes protein
T3355 538-539 -LRB- denotes [
T3356 539-541 CD denotes 18
T3357 541-542 -RRB- denotes ]
T3358 542-543 . denotes .
T3359 543-782 sentence denotes Sequencing of the human genome has led to estimates of approximately 32,000 genes, a total surprise given the previous significantly higher estimates that were based on the number of expressed sequence tags (ESTs) in the public databases.
T3360 544-554 NN denotes Sequencing
T3362 555-557 IN denotes of
T3363 558-561 DT denotes the
T3365 562-567 JJ denotes human
T3364 568-574 NN denotes genome
T3366 575-578 VBZ denotes has
T3361 579-582 VBN denotes led
T3367 583-585 IN denotes to
T3368 586-595 NNS denotes estimates
T3369 596-598 IN denotes of
T3370 599-612 RB denotes approximately
T3371 613-619 CD denotes 32,000
T3372 620-625 NNS denotes genes
T3373 625-627 , denotes ,
T3374 627-628 DT denotes a
T3376 629-634 JJ denotes total
T3375 635-643 NN denotes surprise
T3377 644-649 VBN denotes given
T3378 650-653 DT denotes the
T3380 654-662 JJ denotes previous
T3381 663-676 RB denotes significantly
T3382 677-683 JJR denotes higher
T3379 684-693 NNS denotes estimates
T3383 694-698 WDT denotes that
T3385 699-703 VBD denotes were
T3384 704-709 VBN denotes based
T3386 710-712 IN denotes on
T3387 713-716 DT denotes the
T3388 717-723 NN denotes number
T3389 724-726 IN denotes of
T3390 727-736 VBN denotes expressed
T3392 737-745 NN denotes sequence
T3391 746-750 NNS denotes tags
T3393 751-752 -LRB- denotes (
T3394 752-756 NNS denotes ESTs
T3395 756-757 -RRB- denotes )
T3396 758-760 IN denotes in
T3397 761-764 DT denotes the
T3399 765-771 JJ denotes public
T3398 772-781 NNS denotes databases
T3400 781-782 . denotes .
T3401 782-974 sentence denotes This apparent disparity suggests a major role for alternative splicing in creating genetic complexity, and has brought the study of splicing regulation to the forefront of molecular genetics.
T3402 783-787 DT denotes This
T3404 788-796 JJ denotes apparent
T3403 797-806 NN denotes disparity
T3405 807-815 VBZ denotes suggests
T3406 816-817 DT denotes a
T3408 818-823 JJ denotes major
T3407 824-828 NN denotes role
T3409 829-832 IN denotes for
T3410 833-844 JJ denotes alternative
T3411 845-853 NN denotes splicing
T3412 854-856 IN denotes in
T3413 857-865 VBG denotes creating
T3414 866-873 JJ denotes genetic
T3415 874-884 NN denotes complexity
T3416 884-886 , denotes ,
T3417 886-889 CC denotes and
T3418 890-893 VBZ denotes has
T3419 894-901 VBN denotes brought
T3420 902-905 DT denotes the
T3421 906-911 NN denotes study
T3422 912-914 IN denotes of
T3423 915-923 NN denotes splicing
T3424 924-934 NN denotes regulation
T3425 935-937 IN denotes to
T3426 938-941 DT denotes the
T3427 942-951 NN denotes forefront
T3428 952-954 IN denotes of
T3429 955-964 JJ denotes molecular
T3430 965-973 NN denotes genetics
T3431 973-974 . denotes .
T3432 974-1133 sentence denotes It is likely that an abundance of species-specific splice variants will be identified as the characterization of alternatively spliced transcripts progresses.
T3433 975-977 PRP denotes It
T3434 978-980 VBZ denotes is
T3435 981-987 JJ denotes likely
T3436 988-992 IN denotes that
T3438 993-995 DT denotes an
T3439 996-1005 NN denotes abundance
T3440 1006-1008 IN denotes of
T3441 1009-1016 NN denotes species
T3443 1016-1017 HYPH denotes -
T3442 1017-1025 JJ denotes specific
T3445 1026-1032 NN denotes splice
T3444 1033-1041 NNS denotes variants
T3446 1042-1046 MD denotes will
T3447 1047-1049 VB denotes be
T3437 1050-1060 VBN denotes identified
T3448 1061-1063 IN denotes as
T3450 1064-1067 DT denotes the
T3451 1068-1084 NN denotes characterization
T3452 1085-1087 IN denotes of
T3453 1088-1101 RB denotes alternatively
T3454 1102-1109 VBN denotes spliced
T3455 1110-1121 NNS denotes transcripts
T3449 1122-1132 VBZ denotes progresses
T3456 1132-1133 . denotes .
R1999 T3254 T3255 advmod Interestingly,seen
R2000 T3256 T3255 punct ", ",seen
R2001 T3257 T3258 det the,isoform
R2002 T3258 T3255 nsubjpass isoform,seen
R2003 T3259 T3258 amod second,isoform
R2004 T3260 T3258 compound Mcoln1,isoform
R2005 T3261 T3255 auxpass is,seen
R2006 T3262 T3255 neg not,seen
R2007 T3263 T3255 prep in,seen
R2008 T3264 T3263 pobj humans,in
R2009 T3265 T3255 cc and,seen
R2010 T3266 T3267 det the,sequence
R2011 T3267 T3268 nsubjpass sequence,conserved
R2012 T3268 T3255 conj conserved,seen
R2013 T3269 T3267 prep of,sequence
R2014 T3270 T3271 det the,region
R2015 T3271 T3269 pobj region,of
R2016 T3272 T3273 advmod alternatively,spliced
R2017 T3273 T3271 amod spliced,region
R2018 T3274 T3268 auxpass is,conserved
R2019 T3275 T3268 neg not,conserved
R2020 T3276 T3268 prep between,conserved
R2021 T3277 T3276 pobj man,between
R2022 T3278 T3277 cc and,man
R2023 T3279 T3277 conj mouse,man
R2024 T3280 T3255 punct .,seen
R2025 T3282 T3283 prep To,reported
R2026 T3284 T3282 pobj date,To
R2027 T3285 T3283 punct ", ",reported
R2028 T3286 T3287 advmod very,few
R2029 T3287 T3288 amod few,genes
R2030 T3288 T3283 nsubjpass genes,reported
R2031 T3289 T3283 aux have,reported
R2032 T3290 T3283 auxpass been,reported
R2033 T3291 T3292 dep that,show
R2034 T3292 T3283 ccomp show,reported
R2035 T3293 T3294 npadvmod species,specific
R2036 T3294 T3295 amod specific,variants
R2037 T3295 T3292 dobj variants,show
R2038 T3296 T3295 amod alternative,variants
R2039 T3297 T3295 compound splice,variants
R2040 T3298 T3283 punct .,reported
R2041 T3300 T3301 nsubj MOG,has
R2042 T3302 T3300 punct ", ",MOG
R2043 T3303 T3304 compound myelin,oligodendrocyte
R2044 T3304 T3306 compound oligodendrocyte,glycoprotein
R2045 T3305 T3304 punct /,oligodendrocyte
R2046 T3306 T3300 appos glycoprotein,MOG
R2047 T3307 T3301 punct ", ",has
R2048 T3308 T3309 amod many,variants
R2049 T3309 T3301 dobj variants,has
R2050 T3310 T3309 amod different,variants
R2051 T3311 T3309 compound splice,variants
R2052 T3312 T3301 prep in,has
R2053 T3313 T3312 pobj humans,in
R2054 T3314 T3315 dep that,found
R2055 T3315 T3301 ccomp found,has
R2056 T3316 T3315 auxpass are,found
R2057 T3317 T3315 neg not,found
R2058 T3318 T3315 prep in,found
R2059 T3319 T3318 pobj mice,in
R2060 T3320 T3321 punct [,17
R2061 T3321 T3301 parataxis 17,has
R2062 T3322 T3321 punct ],17
R2063 T3323 T3301 punct .,has
R2064 T3325 T3326 nsubj ATP11B,has
R2065 T3327 T3325 punct ", ",ATP11B
R2066 T3328 T3329 det a,ATPase
R2067 T3329 T3325 appos ATPase,ATP11B
R2068 T3330 T3331 compound P,type
R2069 T3331 T3329 compound type,ATPase
R2070 T3332 T3331 punct -,type
R2071 T3333 T3326 punct ", ",has
R2072 T3334 T3335 det a,variant
R2073 T3335 T3326 dobj variant,has
R2074 T3336 T3337 npadvmod rabbit,specific
R2075 T3337 T3335 amod specific,variant
R2076 T3338 T3337 punct -,specific
R2077 T3339 T3335 compound splice,variant
R2078 T3340 T3341 dep that,deletes
R2079 T3341 T3335 relcl deletes,variant
R2080 T3342 T3343 det a,domain
R2081 T3343 T3341 dobj domain,deletes
R2082 T3344 T3343 amod transmembrane,domain
R2083 T3345 T3341 cc and,deletes
R2084 T3346 T3347 advmod therefore,alters
R2085 T3347 T3341 conj alters,deletes
R2086 T3348 T3347 advmod likely,alters
R2087 T3349 T3350 det the,function
R2088 T3350 T3347 dobj function,alters
R2089 T3351 T3350 amod putative,function
R2090 T3352 T3350 prep of,function
R2091 T3353 T3354 det the,protein
R2092 T3354 T3352 pobj protein,of
R2093 T3355 T3356 punct [,18
R2094 T3356 T3326 parataxis 18,has
R2095 T3357 T3356 punct ],18
R2096 T3358 T3326 punct .,has
R2097 T3360 T3361 nsubj Sequencing,led
R2098 T3362 T3360 prep of,Sequencing
R2099 T3363 T3364 det the,genome
R2100 T3364 T3362 pobj genome,of
R2101 T3365 T3364 amod human,genome
R2102 T3366 T3361 aux has,led
R2103 T3367 T3361 prep to,led
R2104 T3368 T3367 pobj estimates,to
R2105 T3369 T3368 prep of,estimates
R2106 T3370 T3371 advmod approximately,"32,000"
R2107 T3371 T3372 nummod "32,000",genes
R2108 T3372 T3369 pobj genes,of
R2109 T3373 T3361 punct ", ",led
R2110 T3374 T3375 det a,surprise
R2111 T3375 T3361 npadvmod surprise,led
R2112 T3376 T3375 amod total,surprise
R2113 T3377 T3375 prep given,surprise
R2114 T3378 T3379 det the,estimates
R2115 T3379 T3377 pobj estimates,given
R2116 T3380 T3379 amod previous,estimates
R2117 T3381 T3382 advmod significantly,higher
R2118 T3382 T3379 amod higher,estimates
R2119 T3383 T3384 dep that,based
R2120 T3384 T3379 relcl based,estimates
R2121 T3385 T3384 auxpass were,based
R2122 T3386 T3384 prep on,based
R2123 T3387 T3388 det the,number
R2124 T3388 T3386 pobj number,on
R2125 T3389 T3388 prep of,number
R2126 T3390 T3391 amod expressed,tags
R2127 T3391 T3389 pobj tags,of
R2128 T3392 T3391 compound sequence,tags
R2129 T3393 T3391 punct (,tags
R2130 T3394 T3391 appos ESTs,tags
R2131 T3395 T3388 punct ),number
R2132 T3396 T3388 prep in,number
R2133 T3397 T3398 det the,databases
R2134 T3398 T3396 pobj databases,in
R2135 T3399 T3398 amod public,databases
R2136 T3400 T3361 punct .,led
R2137 T3402 T3403 det This,disparity
R2138 T3403 T3405 nsubj disparity,suggests
R2139 T3404 T3403 amod apparent,disparity
R2140 T3406 T3407 det a,role
R2141 T3407 T3405 dobj role,suggests
R2142 T3408 T3407 amod major,role
R2143 T3409 T3405 prep for,suggests
R2144 T3410 T3411 amod alternative,splicing
R2145 T3411 T3409 pobj splicing,for
R2146 T3412 T3405 prep in,suggests
R2147 T3413 T3412 pcomp creating,in
R2148 T3414 T3415 amod genetic,complexity
R2149 T3415 T3413 dobj complexity,creating
R2150 T3416 T3405 punct ", ",suggests
R2151 T3417 T3405 cc and,suggests
R2152 T3418 T3419 aux has,brought
R2153 T3419 T3405 conj brought,suggests
R2154 T3420 T3421 det the,study
R2155 T3421 T3419 dobj study,brought
R2156 T3422 T3421 prep of,study
R2157 T3423 T3424 compound splicing,regulation
R2158 T3424 T3422 pobj regulation,of
R2159 T3425 T3419 prep to,brought
R2160 T3426 T3427 det the,forefront
R2161 T3427 T3425 pobj forefront,to
R2162 T3428 T3427 prep of,forefront
R2163 T3429 T3430 amod molecular,genetics
R2164 T3430 T3428 pobj genetics,of
R2165 T3431 T3405 punct .,suggests
R2166 T3433 T3434 nsubj It,is
R2167 T3435 T3434 acomp likely,is
R2168 T3436 T3437 mark that,identified
R2169 T3437 T3434 ccomp identified,is
R2170 T3438 T3439 det an,abundance
R2171 T3439 T3437 nsubjpass abundance,identified
R2172 T3440 T3439 prep of,abundance
R2173 T3441 T3442 npadvmod species,specific
R2174 T3442 T3444 amod specific,variants
R2175 T3443 T3442 punct -,specific
R2176 T3444 T3440 pobj variants,of
R2177 T3445 T3444 compound splice,variants
R2178 T3446 T3437 aux will,identified
R2179 T3447 T3437 auxpass be,identified
R2180 T3448 T3449 mark as,progresses
R2181 T3449 T3437 advcl progresses,identified
R2182 T3450 T3451 det the,characterization
R2183 T3451 T3449 nsubj characterization,progresses
R2184 T3452 T3451 prep of,characterization
R2185 T3453 T3454 advmod alternatively,spliced
R2186 T3454 T3455 amod spliced,transcripts
R2187 T3455 T3452 pobj transcripts,of
R2188 T3456 T3434 punct .,is