| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T3016 |
0-10 |
NN |
denotes |
Comparison |
| T3018 |
11-13 |
IN |
denotes |
of |
| T3019 |
14-20 |
NN |
denotes |
Mcoln1 |
| T3020 |
21-28 |
NN |
denotes |
isoform |
| T3021 |
29-30 |
CD |
denotes |
1 |
| T3022 |
31-33 |
IN |
denotes |
to |
| T3023 |
34-37 |
PRP$ |
denotes |
its |
| T3025 |
38-43 |
JJ |
denotes |
human |
| T3024 |
44-53 |
NN |
denotes |
homologue |
| T3017 |
54-59 |
VBZ |
denotes |
shows |
| T3026 |
60-68 |
JJ |
denotes |
striking |
| T3027 |
69-79 |
NN |
denotes |
similarity |
| T3028 |
80-82 |
IN |
denotes |
at |
| T3029 |
83-87 |
CC |
denotes |
both |
| T3031 |
88-91 |
DT |
denotes |
the |
| T3032 |
92-97 |
NN |
denotes |
amino |
| T3033 |
98-102 |
NN |
denotes |
acid |
| T3034 |
103-106 |
CC |
denotes |
and |
| T3035 |
107-117 |
NN |
denotes |
nucleotide |
| T3030 |
118-123 |
NN |
denotes |
level |
| T3036 |
123-124 |
. |
denotes |
. |
| T3037 |
124-223 |
sentence |
denotes |
All six of the transmembrane domains, as well as the putative cation channel are highly conserved. |
| T3038 |
125-128 |
DT |
denotes |
All |
| T3039 |
129-132 |
CD |
denotes |
six |
| T3041 |
133-135 |
IN |
denotes |
of |
| T3042 |
136-139 |
DT |
denotes |
the |
| T3044 |
140-153 |
NN |
denotes |
transmembrane |
| T3043 |
154-161 |
NNS |
denotes |
domains |
| T3045 |
161-163 |
, |
denotes |
, |
| T3046 |
163-165 |
RB |
denotes |
as |
| T3048 |
166-170 |
RB |
denotes |
well |
| T3047 |
171-173 |
IN |
denotes |
as |
| T3049 |
174-177 |
DT |
denotes |
the |
| T3051 |
178-186 |
JJ |
denotes |
putative |
| T3052 |
187-193 |
NN |
denotes |
cation |
| T3050 |
194-201 |
NN |
denotes |
channel |
| T3053 |
202-205 |
VBP |
denotes |
are |
| T3054 |
206-212 |
RB |
denotes |
highly |
| T3040 |
213-222 |
VBN |
denotes |
conserved |
| T3055 |
222-223 |
. |
denotes |
. |
| T3056 |
223-367 |
sentence |
denotes |
The putative di-leucine (L-L-X-X) motif at the C-terminus, which may act as a late endosomal/lysosomal targeting signal, is also conserved [9]. |
| T3057 |
224-227 |
DT |
denotes |
The |
| T3059 |
228-236 |
JJ |
denotes |
putative |
| T3060 |
237-247 |
NN |
denotes |
di-leucine |
| T3061 |
248-249 |
-LRB- |
denotes |
( |
| T3063 |
249-250 |
NN |
denotes |
L |
| T3064 |
250-251 |
HYPH |
denotes |
- |
| T3065 |
251-252 |
NN |
denotes |
L |
| T3066 |
252-253 |
HYPH |
denotes |
- |
| T3067 |
253-254 |
NN |
denotes |
X |
| T3068 |
254-255 |
HYPH |
denotes |
- |
| T3062 |
255-256 |
NN |
denotes |
X |
| T3069 |
256-257 |
-RRB- |
denotes |
) |
| T3058 |
258-263 |
NN |
denotes |
motif |
| T3071 |
264-266 |
IN |
denotes |
at |
| T3072 |
267-270 |
DT |
denotes |
the |
| T3074 |
271-272 |
NN |
denotes |
C |
| T3075 |
272-273 |
HYPH |
denotes |
- |
| T3073 |
273-281 |
NN |
denotes |
terminus |
| T3076 |
281-283 |
, |
denotes |
, |
| T3077 |
283-288 |
WDT |
denotes |
which |
| T3079 |
289-292 |
MD |
denotes |
may |
| T3078 |
293-296 |
VB |
denotes |
act |
| T3080 |
297-299 |
IN |
denotes |
as |
| T3081 |
300-301 |
DT |
denotes |
a |
| T3083 |
302-306 |
JJ |
denotes |
late |
| T3084 |
307-316 |
JJ |
denotes |
endosomal |
| T3086 |
316-317 |
HYPH |
denotes |
/ |
| T3085 |
317-326 |
JJ |
denotes |
lysosomal |
| T3087 |
327-336 |
NN |
denotes |
targeting |
| T3082 |
337-343 |
NN |
denotes |
signal |
| T3088 |
343-345 |
, |
denotes |
, |
| T3089 |
345-347 |
VBZ |
denotes |
is |
| T3090 |
348-352 |
RB |
denotes |
also |
| T3070 |
353-362 |
VBN |
denotes |
conserved |
| T3091 |
363-364 |
-LRB- |
denotes |
[ |
| T3092 |
364-365 |
CD |
denotes |
9 |
| T3093 |
365-366 |
-RRB- |
denotes |
] |
| T3094 |
366-367 |
. |
denotes |
. |
| T3095 |
367-567 |
sentence |
denotes |
This speculation is supported by work with cup-5[13], the c. elegans homologue of MCOLN1, since cellular localization studies suggest that the protein is found in the late endosomes and/or lysosomes. |
| T3096 |
368-372 |
DT |
denotes |
This |
| T3097 |
373-384 |
NN |
denotes |
speculation |
| T3099 |
385-387 |
VBZ |
denotes |
is |
| T3098 |
388-397 |
VBN |
denotes |
supported |
| T3100 |
398-400 |
IN |
denotes |
by |
| T3101 |
401-405 |
NN |
denotes |
work |
| T3102 |
406-410 |
IN |
denotes |
with |
| T3103 |
411-414 |
NN |
denotes |
cup |
| T3105 |
414-415 |
HYPH |
denotes |
- |
| T3104 |
415-416 |
NN |
denotes |
5 |
| T3106 |
416-417 |
-LRB- |
denotes |
[ |
| T3107 |
417-419 |
CD |
denotes |
13 |
| T3108 |
419-420 |
-RRB- |
denotes |
] |
| T3109 |
420-422 |
, |
denotes |
, |
| T3110 |
422-425 |
DT |
denotes |
the |
| T3112 |
426-428 |
NNP |
denotes |
c. |
| T3113 |
429-436 |
NNP |
denotes |
elegans |
| T3111 |
437-446 |
NN |
denotes |
homologue |
| T3114 |
447-449 |
IN |
denotes |
of |
| T3115 |
450-456 |
NN |
denotes |
MCOLN1 |
| T3116 |
456-458 |
, |
denotes |
, |
| T3117 |
458-463 |
IN |
denotes |
since |
| T3119 |
464-472 |
JJ |
denotes |
cellular |
| T3120 |
473-485 |
NN |
denotes |
localization |
| T3121 |
486-493 |
NNS |
denotes |
studies |
| T3118 |
494-501 |
VBP |
denotes |
suggest |
| T3122 |
502-506 |
IN |
denotes |
that |
| T3124 |
507-510 |
DT |
denotes |
the |
| T3125 |
511-518 |
NN |
denotes |
protein |
| T3126 |
519-521 |
VBZ |
denotes |
is |
| T3123 |
522-527 |
VBN |
denotes |
found |
| T3127 |
528-530 |
IN |
denotes |
in |
| T3128 |
531-534 |
DT |
denotes |
the |
| T3130 |
535-539 |
JJ |
denotes |
late |
| T3129 |
540-549 |
NNS |
denotes |
endosomes |
| T3131 |
550-553 |
CC |
denotes |
and |
| T3132 |
553-554 |
HYPH |
denotes |
/ |
| T3133 |
554-556 |
CC |
denotes |
or |
| T3134 |
557-566 |
NNS |
denotes |
lysosomes |
| T3135 |
566-567 |
. |
denotes |
. |
| R1777 |
T3016 |
T3017 |
nsubj |
Comparison,shows |
| R1778 |
T3018 |
T3016 |
prep |
of,Comparison |
| R1779 |
T3019 |
T3020 |
compound |
Mcoln1,isoform |
| R1780 |
T3020 |
T3018 |
pobj |
isoform,of |
| R1781 |
T3021 |
T3020 |
nummod |
1,isoform |
| R1782 |
T3022 |
T3016 |
prep |
to,Comparison |
| R1783 |
T3023 |
T3024 |
poss |
its,homologue |
| R1784 |
T3024 |
T3022 |
pobj |
homologue,to |
| R1785 |
T3025 |
T3024 |
amod |
human,homologue |
| R1786 |
T3026 |
T3027 |
amod |
striking,similarity |
| R1787 |
T3027 |
T3017 |
dobj |
similarity,shows |
| R1788 |
T3028 |
T3017 |
prep |
at,shows |
| R1789 |
T3029 |
T3030 |
preconj |
both,level |
| R1790 |
T3030 |
T3028 |
pobj |
level,at |
| R1791 |
T3031 |
T3030 |
det |
the,level |
| R1792 |
T3032 |
T3033 |
nmod |
amino,acid |
| R1793 |
T3033 |
T3030 |
nmod |
acid,level |
| R1794 |
T3034 |
T3033 |
cc |
and,acid |
| R1795 |
T3035 |
T3033 |
conj |
nucleotide,acid |
| R1796 |
T3036 |
T3017 |
punct |
.,shows |
| R1797 |
T3038 |
T3039 |
det |
All,six |
| R1798 |
T3039 |
T3040 |
nsubjpass |
six,conserved |
| R1799 |
T3041 |
T3039 |
prep |
of,six |
| R1800 |
T3042 |
T3043 |
det |
the,domains |
| R1801 |
T3043 |
T3041 |
pobj |
domains,of |
| R1802 |
T3044 |
T3043 |
compound |
transmembrane,domains |
| R1803 |
T3045 |
T3039 |
punct |
", ",six |
| R1804 |
T3046 |
T3047 |
advmod |
as,as |
| R1805 |
T3047 |
T3039 |
cc |
as,six |
| R1806 |
T3048 |
T3047 |
advmod |
well,as |
| R1807 |
T3049 |
T3050 |
det |
the,channel |
| R1808 |
T3050 |
T3039 |
conj |
channel,six |
| R1809 |
T3051 |
T3050 |
amod |
putative,channel |
| R1810 |
T3052 |
T3050 |
compound |
cation,channel |
| R1811 |
T3053 |
T3040 |
auxpass |
are,conserved |
| R1812 |
T3054 |
T3040 |
advmod |
highly,conserved |
| R1813 |
T3055 |
T3040 |
punct |
.,conserved |
| R1814 |
T3057 |
T3058 |
det |
The,motif |
| R1815 |
T3058 |
T3070 |
nsubjpass |
motif,conserved |
| R1816 |
T3059 |
T3058 |
amod |
putative,motif |
| R1817 |
T3060 |
T3058 |
nmod |
di-leucine,motif |
| R1818 |
T3061 |
T3062 |
punct |
(,X |
| R1819 |
T3062 |
T3060 |
parataxis |
X,di-leucine |
| R1820 |
T3063 |
T3062 |
compound |
L,X |
| R1821 |
T3064 |
T3062 |
punct |
-,X |
| R1822 |
T3065 |
T3062 |
compound |
L,X |
| R1823 |
T3066 |
T3062 |
punct |
-,X |
| R1824 |
T3067 |
T3062 |
compound |
X,X |
| R1825 |
T3068 |
T3062 |
punct |
-,X |
| R1826 |
T3069 |
T3062 |
punct |
),X |
| R1827 |
T3071 |
T3058 |
prep |
at,motif |
| R1828 |
T3072 |
T3073 |
det |
the,terminus |
| R1829 |
T3073 |
T3071 |
pobj |
terminus,at |
| R1830 |
T3074 |
T3073 |
compound |
C,terminus |
| R1831 |
T3075 |
T3073 |
punct |
-,terminus |
| R1832 |
T3076 |
T3058 |
punct |
", ",motif |
| R1833 |
T3077 |
T3078 |
dep |
which,act |
| R1834 |
T3078 |
T3058 |
relcl |
act,motif |
| R1835 |
T3079 |
T3078 |
aux |
may,act |
| R1836 |
T3080 |
T3078 |
prep |
as,act |
| R1837 |
T3081 |
T3082 |
det |
a,signal |
| R1838 |
T3082 |
T3080 |
pobj |
signal,as |
| R1839 |
T3083 |
T3082 |
amod |
late,signal |
| R1840 |
T3084 |
T3085 |
amod |
endosomal,lysosomal |
| R1841 |
T3085 |
T3082 |
amod |
lysosomal,signal |
| R1842 |
T3086 |
T3085 |
punct |
/,lysosomal |
| R1843 |
T3087 |
T3082 |
compound |
targeting,signal |
| R1844 |
T3088 |
T3070 |
punct |
", ",conserved |
| R1845 |
T3089 |
T3070 |
auxpass |
is,conserved |
| R1846 |
T3090 |
T3070 |
advmod |
also,conserved |
| R1847 |
T3091 |
T3092 |
punct |
[,9 |
| R1848 |
T3092 |
T3070 |
parataxis |
9,conserved |
| R1849 |
T3093 |
T3092 |
punct |
],9 |
| R1850 |
T3094 |
T3070 |
punct |
.,conserved |
| R1851 |
T3096 |
T3097 |
det |
This,speculation |
| R1852 |
T3097 |
T3098 |
nsubjpass |
speculation,supported |
| R1853 |
T3099 |
T3098 |
auxpass |
is,supported |
| R1854 |
T3100 |
T3098 |
agent |
by,supported |
| R1855 |
T3101 |
T3100 |
pobj |
work,by |
| R1856 |
T3102 |
T3101 |
prep |
with,work |
| R1857 |
T3103 |
T3104 |
compound |
cup,5 |
| R1858 |
T3104 |
T3102 |
pobj |
5,with |
| R1859 |
T3105 |
T3104 |
punct |
-,5 |
| R1860 |
T3106 |
T3107 |
punct |
[,13 |
| R1861 |
T3107 |
T3101 |
parataxis |
13,work |
| R1862 |
T3108 |
T3107 |
punct |
],13 |
| R1863 |
T3109 |
T3101 |
punct |
", ",work |
| R1864 |
T3110 |
T3111 |
det |
the,homologue |
| R1865 |
T3111 |
T3101 |
appos |
homologue,work |
| R1866 |
T3112 |
T3113 |
compound |
c.,elegans |
| R1867 |
T3113 |
T3111 |
compound |
elegans,homologue |
| R1868 |
T3114 |
T3111 |
prep |
of,homologue |
| R1869 |
T3115 |
T3114 |
pobj |
MCOLN1,of |
| R1870 |
T3116 |
T3098 |
punct |
", ",supported |
| R1871 |
T3117 |
T3118 |
mark |
since,suggest |
| R1872 |
T3118 |
T3098 |
advcl |
suggest,supported |
| R1873 |
T3119 |
T3120 |
amod |
cellular,localization |
| R1874 |
T3120 |
T3121 |
compound |
localization,studies |
| R1875 |
T3121 |
T3118 |
nsubj |
studies,suggest |
| R1876 |
T3122 |
T3123 |
mark |
that,found |
| R1877 |
T3123 |
T3118 |
ccomp |
found,suggest |
| R1878 |
T3124 |
T3125 |
det |
the,protein |
| R1879 |
T3125 |
T3123 |
nsubjpass |
protein,found |
| R1880 |
T3126 |
T3123 |
auxpass |
is,found |
| R1881 |
T3127 |
T3123 |
prep |
in,found |
| R1882 |
T3128 |
T3129 |
det |
the,endosomes |
| R1883 |
T3129 |
T3127 |
pobj |
endosomes,in |
| R1884 |
T3130 |
T3129 |
amod |
late,endosomes |
| R1885 |
T3131 |
T3129 |
cc |
and,endosomes |
| R1886 |
T3132 |
T3131 |
punct |
/,and |
| R1887 |
T3133 |
T3131 |
cc |
or,and |
| R1888 |
T3134 |
T3129 |
conj |
lysosomes,endosomes |
| R1889 |
T3135 |
T3098 |
punct |
.,supported |
