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PMC:88885 / 1044-1606 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T308 0-6 NN denotes Mcoln1
T309 7-9 VBZ denotes is
T310 10-16 RB denotes highly
T311 17-24 JJ denotes similar
T312 25-27 IN denotes to
T313 28-34 NN denotes MCOLN1
T314 34-36 , denotes ,
T315 36-46 RB denotes especially
T316 47-49 IN denotes in
T317 50-53 DT denotes the
T319 54-67 NN denotes transmembrane
T318 68-75 NNS denotes domains
T320 76-79 CC denotes and
T321 80-83 NN denotes ion
T322 84-88 NN denotes pore
T323 89-95 NN denotes region
T324 95-96 . denotes .
T325 96-246 sentence denotes Also, the late endosomal/lysosomal targeting signal is conserved, supporting the hypothesis that the protein is localized to these vesicle membranes.
T326 97-101 RB denotes Also
T328 101-103 , denotes ,
T329 103-106 DT denotes the
T331 107-111 JJ denotes late
T332 112-121 JJ denotes endosomal
T334 121-122 HYPH denotes /
T333 122-131 JJ denotes lysosomal
T335 132-141 NN denotes targeting
T330 142-148 NN denotes signal
T336 149-151 VBZ denotes is
T327 152-161 VBN denotes conserved
T337 161-163 , denotes ,
T338 163-173 VBG denotes supporting
T339 174-177 DT denotes the
T340 178-188 NN denotes hypothesis
T341 189-193 IN denotes that
T343 194-197 DT denotes the
T344 198-205 NN denotes protein
T345 206-208 VBZ denotes is
T342 209-218 VBN denotes localized
T346 219-221 IN denotes to
T347 222-227 DT denotes these
T349 228-235 NN denotes vesicle
T348 236-245 NNS denotes membranes
T350 245-246 . denotes .
T351 246-327 sentence denotes To date, there are very few reports describing species-specific splice variants.
T352 247-249 IN denotes To
T354 250-254 NN denotes date
T355 254-256 , denotes ,
T356 256-261 EX denotes there
T353 262-265 VBP denotes are
T357 266-270 RB denotes very
T358 271-274 JJ denotes few
T359 275-282 NNS denotes reports
T360 283-293 VBG denotes describing
T361 294-301 NN denotes species
T363 301-302 HYPH denotes -
T362 302-310 JJ denotes specific
T365 311-317 NN denotes splice
T364 318-326 NNS denotes variants
T366 326-327 . denotes .
T367 327-562 sentence denotes While identification of Mcoln1 is crucial to the development of mouse models for MLIV, the fact that there are two transcripts in mice suggests an additional or alternate function of the gene that may complicate phenotypic assessment.
T368 328-333 IN denotes While
T370 334-348 NN denotes identification
T371 349-351 IN denotes of
T372 352-358 NN denotes Mcoln1
T369 359-361 VBZ denotes is
T374 362-369 JJ denotes crucial
T375 370-372 IN denotes to
T376 373-376 DT denotes the
T377 377-388 NN denotes development
T378 389-391 IN denotes of
T379 392-397 NN denotes mouse
T380 398-404 NNS denotes models
T381 405-408 IN denotes for
T382 409-413 NN denotes MLIV
T383 413-415 , denotes ,
T384 415-418 DT denotes the
T385 419-423 NN denotes fact
T386 424-428 IN denotes that
T388 429-434 EX denotes there
T387 435-438 VBP denotes are
T389 439-442 CD denotes two
T390 443-454 NNS denotes transcripts
T391 455-457 IN denotes in
T392 458-462 NNS denotes mice
T373 463-471 VBZ denotes suggests
T393 472-474 DT denotes an
T395 475-485 JJ denotes additional
T396 486-488 CC denotes or
T397 489-498 JJ denotes alternate
T394 499-507 NN denotes function
T398 508-510 IN denotes of
T399 511-514 DT denotes the
T400 515-519 NN denotes gene
T401 520-524 WDT denotes that
T403 525-528 MD denotes may
T402 529-539 VB denotes complicate
T404 540-550 JJ denotes phenotypic
T405 551-561 NN denotes assessment
T406 561-562 . denotes .
R173 T308 T309 nsubj Mcoln1,is
R174 T310 T311 advmod highly,similar
R175 T311 T309 acomp similar,is
R176 T312 T311 prep to,similar
R177 T313 T312 pobj MCOLN1,to
R178 T314 T309 punct ", ",is
R179 T315 T316 advmod especially,in
R180 T316 T309 prep in,is
R181 T317 T318 det the,domains
R182 T318 T316 pobj domains,in
R183 T319 T318 compound transmembrane,domains
R184 T320 T318 cc and,domains
R185 T321 T322 compound ion,pore
R186 T322 T323 compound pore,region
R187 T323 T318 conj region,domains
R188 T324 T309 punct .,is
R189 T326 T327 advmod Also,conserved
R190 T328 T327 punct ", ",conserved
R191 T329 T330 det the,signal
R192 T330 T327 nsubjpass signal,conserved
R193 T331 T330 amod late,signal
R194 T332 T333 amod endosomal,lysosomal
R195 T333 T330 amod lysosomal,signal
R196 T334 T333 punct /,lysosomal
R197 T335 T330 compound targeting,signal
R198 T336 T327 auxpass is,conserved
R199 T337 T327 punct ", ",conserved
R200 T338 T327 advcl supporting,conserved
R201 T339 T340 det the,hypothesis
R202 T340 T338 dobj hypothesis,supporting
R203 T341 T342 mark that,localized
R204 T342 T340 acl localized,hypothesis
R205 T343 T344 det the,protein
R206 T344 T342 nsubjpass protein,localized
R207 T345 T342 auxpass is,localized
R208 T346 T342 prep to,localized
R209 T347 T348 det these,membranes
R210 T348 T346 pobj membranes,to
R211 T349 T348 compound vesicle,membranes
R212 T350 T327 punct .,conserved
R213 T352 T353 prep To,are
R214 T354 T352 pobj date,To
R215 T355 T353 punct ", ",are
R216 T356 T353 expl there,are
R217 T357 T358 advmod very,few
R218 T358 T359 amod few,reports
R219 T359 T353 attr reports,are
R220 T360 T359 acl describing,reports
R221 T361 T362 npadvmod species,specific
R222 T362 T364 amod specific,variants
R223 T363 T362 punct -,specific
R224 T364 T360 dobj variants,describing
R225 T365 T364 compound splice,variants
R226 T366 T353 punct .,are
R227 T368 T369 mark While,is
R228 T369 T373 advcl is,suggests
R229 T370 T369 nsubj identification,is
R230 T371 T370 prep of,identification
R231 T372 T371 pobj Mcoln1,of
R232 T374 T369 acomp crucial,is
R233 T375 T374 prep to,crucial
R234 T376 T377 det the,development
R235 T377 T375 pobj development,to
R236 T378 T377 prep of,development
R237 T379 T380 compound mouse,models
R238 T380 T378 pobj models,of
R239 T381 T377 prep for,development
R240 T382 T381 pobj MLIV,for
R241 T383 T373 punct ", ",suggests
R242 T384 T385 det the,fact
R243 T385 T373 nsubj fact,suggests
R244 T386 T387 mark that,are
R245 T387 T385 acl are,fact
R246 T388 T387 expl there,are
R247 T389 T390 nummod two,transcripts
R248 T390 T387 attr transcripts,are
R249 T391 T387 prep in,are
R250 T392 T391 pobj mice,in
R251 T393 T394 det an,function
R252 T394 T373 dobj function,suggests
R253 T395 T394 amod additional,function
R254 T396 T395 cc or,additional
R255 T397 T395 conj alternate,additional
R256 T398 T394 prep of,function
R257 T399 T400 det the,gene
R258 T400 T398 pobj gene,of
R259 T401 T402 dep that,complicate
R260 T402 T394 relcl complicate,function
R261 T403 T402 aux may,complicate
R262 T404 T405 amod phenotypic,assessment
R263 T405 T402 dobj assessment,complicate
R264 T406 T373 punct .,suggests