PMC:549712 / 533-1334 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T353 0-7 NNS denotes Results
T354 7-193 sentence denotes Ablation of Ptdsr function in mice causes perinatal lethality, growth retardation and a delay in terminal differentiation of the kidney, intestine, liver and lungs during embryogenesis.
T355 8-16 NN denotes Ablation
T357 17-19 IN denotes of
T358 20-25 NN denotes Ptdsr
T359 26-34 NN denotes function
T360 35-37 IN denotes in
T361 38-42 NNS denotes mice
T356 43-49 VBZ denotes causes
T362 50-59 JJ denotes perinatal
T363 60-69 NN denotes lethality
T364 69-71 , denotes ,
T365 71-77 NN denotes growth
T366 78-89 NN denotes retardation
T367 90-93 CC denotes and
T368 94-95 DT denotes a
T369 96-101 NN denotes delay
T370 102-104 IN denotes in
T371 105-113 JJ denotes terminal
T372 114-129 NN denotes differentiation
T373 130-132 IN denotes of
T374 133-136 DT denotes the
T375 137-143 NN denotes kidney
T376 143-145 , denotes ,
T377 145-154 NN denotes intestine
T378 154-156 , denotes ,
T379 156-161 NN denotes liver
T380 162-165 CC denotes and
T381 166-171 NNS denotes lungs
T382 172-178 IN denotes during
T383 179-192 NN denotes embryogenesis
T384 192-193 . denotes .
T385 193-347 sentence denotes Moreover, eye development can be severely disturbed, ranging from defects in retinal differentiation to complete unilateral or bilateral absence of eyes.
T386 194-202 RB denotes Moreover
T388 202-204 , denotes ,
T389 204-207 NN denotes eye
T390 208-219 NN denotes development
T391 220-223 MD denotes can
T392 224-226 VB denotes be
T393 227-235 RB denotes severely
T387 236-245 VBN denotes disturbed
T394 245-247 , denotes ,
T395 247-254 VBG denotes ranging
T396 255-259 IN denotes from
T397 260-267 NNS denotes defects
T398 268-270 IN denotes in
T399 271-278 JJ denotes retinal
T400 279-294 NN denotes differentiation
T401 295-297 IN denotes to
T402 298-306 JJ denotes complete
T404 307-317 JJ denotes unilateral
T405 318-320 CC denotes or
T406 321-330 JJ denotes bilateral
T403 331-338 NN denotes absence
T407 339-341 IN denotes of
T408 342-346 NNS denotes eyes
T409 346-347 . denotes .
T410 347-477 sentence denotes Ptdsr -/- mice with anophthalmia develop novel lesions, with induction of ectopic retinal-pigmented epithelium in nasal cavities.
T411 348-353 NN denotes Ptdsr
T413 354-355 SYM denotes -
T414 355-356 HYPH denotes /
T415 356-357 SYM denotes -
T412 358-362 NNS denotes mice
T417 363-367 IN denotes with
T418 368-380 NN denotes anophthalmia
T416 381-388 VBP denotes develop
T419 389-394 JJ denotes novel
T420 395-402 NNS denotes lesions
T421 402-404 , denotes ,
T422 404-408 IN denotes with
T423 409-418 NN denotes induction
T424 419-421 IN denotes of
T425 422-429 JJ denotes ectopic
T427 430-437 RB denotes retinal
T429 437-438 HYPH denotes -
T428 438-447 VBN denotes pigmented
T426 448-458 NN denotes epithelium
T430 459-461 IN denotes in
T431 462-467 JJ denotes nasal
T432 468-476 NNS denotes cavities
T433 476-477 . denotes .
T434 477-801 sentence denotes A comprehensive investigation of apoptotic cell clearance in vivo and in vitro demonstrated that engulfment of apoptotic cells was normal in Ptdsr knockout mice, but Ptdsr-deficient macrophages were impaired in pro- and anti-inflammatory cytokine signaling after stimulation with apoptotic cells or with lipopolysaccharide.
T435 478-479 DT denotes A
T437 480-493 JJ denotes comprehensive
T436 494-507 NN denotes investigation
T439 508-510 IN denotes of
T440 511-520 JJ denotes apoptotic
T442 521-525 NN denotes cell
T441 526-535 NN denotes clearance
T443 536-538 FW denotes in
T444 539-543 FW denotes vivo
T445 544-547 CC denotes and
T446 548-550 FW denotes in
T447 551-556 FW denotes vitro
T438 557-569 VBD denotes demonstrated
T448 570-574 IN denotes that
T450 575-585 NN denotes engulfment
T451 586-588 IN denotes of
T452 589-598 JJ denotes apoptotic
T453 599-604 NNS denotes cells
T449 605-608 VBD denotes was
T454 609-615 JJ denotes normal
T455 616-618 IN denotes in
T456 619-624 NN denotes Ptdsr
T458 625-633 NN denotes knockout
T457 634-638 NNS denotes mice
T459 638-640 , denotes ,
T460 640-643 CC denotes but
T461 644-649 NN denotes Ptdsr
T463 649-650 HYPH denotes -
T462 650-659 JJ denotes deficient
T464 660-671 NNS denotes macrophages
T466 672-676 VBD denotes were
T465 677-685 VBN denotes impaired
T467 686-688 IN denotes in
T468 689-692 AFX denotes pro
T470 692-693 HYPH denotes -
T471 694-697 CC denotes and
T469 698-715 JJ denotes anti-inflammatory
T473 716-724 NN denotes cytokine
T472 725-734 NN denotes signaling
T474 735-740 IN denotes after
T475 741-752 NN denotes stimulation
T476 753-757 IN denotes with
T477 758-767 JJ denotes apoptotic
T478 768-773 NNS denotes cells
T479 774-776 CC denotes or
T480 777-781 IN denotes with
T481 782-800 NN denotes lipopolysaccharide
T482 800-801 . denotes .
R100 T381 T379 conj lungs,liver
R101 T382 T369 prep during,delay
R102 T383 T382 pobj embryogenesis,during
R103 T384 T356 punct .,causes
R104 T386 T387 advmod Moreover,disturbed
R105 T388 T387 punct ", ",disturbed
R106 T389 T390 compound eye,development
R107 T390 T387 nsubjpass development,disturbed
R108 T391 T387 aux can,disturbed
R109 T392 T387 auxpass be,disturbed
R110 T393 T387 advmod severely,disturbed
R111 T394 T387 punct ", ",disturbed
R112 T395 T387 advcl ranging,disturbed
R113 T396 T395 prep from,ranging
R114 T397 T396 pobj defects,from
R115 T398 T397 prep in,defects
R116 T399 T400 amod retinal,differentiation
R117 T400 T398 pobj differentiation,in
R118 T401 T396 prep to,from
R119 T402 T403 amod complete,absence
R120 T403 T401 pobj absence,to
R121 T404 T403 amod unilateral,absence
R122 T405 T404 cc or,unilateral
R123 T406 T404 conj bilateral,unilateral
R124 T407 T403 prep of,absence
R125 T408 T407 pobj eyes,of
R126 T409 T387 punct .,disturbed
R127 T411 T412 nmod Ptdsr,mice
R128 T412 T416 nsubj mice,develop
R129 T413 T411 punct -,Ptdsr
R130 T414 T411 punct /,Ptdsr
R131 T415 T411 punct -,Ptdsr
R132 T417 T412 prep with,mice
R133 T418 T417 pobj anophthalmia,with
R134 T419 T420 amod novel,lesions
R135 T420 T416 dobj lesions,develop
R136 T421 T420 punct ", ",lesions
R137 T422 T420 prep with,lesions
R138 T423 T422 pobj induction,with
R139 T424 T423 prep of,induction
R140 T425 T426 amod ectopic,epithelium
R141 T426 T424 pobj epithelium,of
R142 T427 T428 advmod retinal,pigmented
R143 T428 T426 amod pigmented,epithelium
R144 T429 T428 punct -,pigmented
R145 T430 T423 prep in,induction
R146 T431 T432 amod nasal,cavities
R147 T432 T430 pobj cavities,in
R148 T433 T416 punct .,develop
R149 T435 T436 det A,investigation
R150 T436 T438 nsubj investigation,demonstrated
R151 T437 T436 amod comprehensive,investigation
R152 T439 T436 prep of,investigation
R153 T440 T441 amod apoptotic,clearance
R154 T441 T439 pobj clearance,of
R155 T442 T441 compound cell,clearance
R156 T443 T444 advmod in,vivo
R157 T444 T436 advmod vivo,investigation
R158 T445 T444 cc and,vivo
R159 T446 T447 advmod in,vitro
R160 T447 T444 conj vitro,vivo
R161 T448 T449 mark that,was
R162 T449 T438 ccomp was,demonstrated
R163 T450 T449 nsubj engulfment,was
R164 T451 T450 prep of,engulfment
R165 T452 T453 amod apoptotic,cells
R166 T453 T451 pobj cells,of
R167 T454 T449 acomp normal,was
R168 T455 T449 prep in,was
R169 T456 T457 compound Ptdsr,mice
R170 T457 T455 pobj mice,in
R171 T458 T457 compound knockout,mice
R172 T459 T438 punct ", ",demonstrated
R173 T460 T438 cc but,demonstrated
R174 T461 T462 npadvmod Ptdsr,deficient
R175 T462 T464 amod deficient,macrophages
R176 T463 T462 punct -,deficient
R177 T464 T465 nsubjpass macrophages,impaired
R178 T465 T438 conj impaired,demonstrated
R179 T466 T465 auxpass were,impaired
R180 T467 T465 prep in,impaired
R181 T468 T469 advmod pro,anti-inflammatory
R182 T469 T472 amod anti-inflammatory,signaling
R183 T470 T469 punct -,anti-inflammatory
R184 T471 T469 cc and,anti-inflammatory
R185 T472 T467 pobj signaling,in
R186 T473 T472 compound cytokine,signaling
R187 T474 T465 prep after,impaired
R188 T475 T474 pobj stimulation,after
R189 T476 T475 prep with,stimulation
R190 T477 T478 amod apoptotic,cells
R191 T478 T476 pobj cells,with
R192 T479 T476 cc or,with
R193 T480 T476 conj with,with
R194 T481 T480 pobj lipopolysaccharide,with
R195 T482 T465 punct .,impaired
R75 T355 T356 nsubj Ablation,causes
R76 T357 T355 prep of,Ablation
R77 T358 T359 compound Ptdsr,function
R78 T359 T357 pobj function,of
R79 T360 T355 prep in,Ablation
R80 T361 T360 pobj mice,in
R81 T362 T363 amod perinatal,lethality
R82 T363 T356 dobj lethality,causes
R83 T364 T363 punct ", ",lethality
R84 T365 T366 compound growth,retardation
R85 T366 T363 conj retardation,lethality
R86 T367 T366 cc and,retardation
R87 T368 T369 det a,delay
R88 T369 T366 conj delay,retardation
R89 T370 T369 prep in,delay
R90 T371 T372 amod terminal,differentiation
R91 T372 T370 pobj differentiation,in
R92 T373 T372 prep of,differentiation
R93 T374 T375 det the,kidney
R94 T375 T373 pobj kidney,of
R95 T376 T375 punct ", ",kidney
R96 T377 T375 conj intestine,kidney
R97 T378 T377 punct ", ",intestine
R98 T379 T377 conj liver,intestine
R99 T380 T379 cc and,liver