craft-sa-dev Home  

PMC:549712 / 47950-49009 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T14088 11-14 PRP$ denotes Our
T14089 15-22 NNS denotes results
T14090 23-34 VBP denotes demonstrate
T14091 35-39 IN denotes that
T14093 40-45 NN denotes Ptdsr
T14092 46-48 VBZ denotes is
T14094 49-58 JJ denotes essential
T14095 59-62 IN denotes for
T14096 63-66 DT denotes the
T14097 67-82 NN denotes differentiation
T14098 83-86 CC denotes and
T14099 87-97 NN denotes maturation
T14100 98-100 IN denotes of
T14101 101-109 JJ denotes multiple
T14102 110-117 NNS denotes tissues
T14103 118-124 IN denotes during
T14104 125-138 NN denotes embryogenesis
T14105 138-139 . denotes .
T14106 139-255 sentence denotes Ablation of Ptdsr function results in neonatal lethality and severe defects in the morphogenesis of several organs.
T14107 140-148 NN denotes Ablation
T14109 149-151 IN denotes of
T14110 152-157 NN denotes Ptdsr
T14111 158-166 NN denotes function
T14108 167-174 VBZ denotes results
T14112 175-177 IN denotes in
T14113 178-186 JJ denotes neonatal
T14114 187-196 NN denotes lethality
T14115 197-200 CC denotes and
T14116 201-207 JJ denotes severe
T14117 208-215 NNS denotes defects
T14118 216-218 IN denotes in
T14119 219-222 DT denotes the
T14120 223-236 NN denotes morphogenesis
T14121 237-239 IN denotes of
T14122 240-247 JJ denotes several
T14123 248-254 NNS denotes organs
T14124 254-255 . denotes .
T14125 255-409 sentence denotes The developmental malformations cannot be explained by impaired clearance of apoptotic cells, a process that proved to be normal in Ptdsr-deficient mice.
T14126 256-259 DT denotes The
T14128 260-273 JJ denotes developmental
T14127 274-287 NNS denotes malformations
T14130 288-291 MD denotes can
T14131 291-294 RB denotes not
T14132 295-297 VB denotes be
T14129 298-307 VBN denotes explained
T14133 308-310 IN denotes by
T14134 311-319 JJ denotes impaired
T14135 320-329 NN denotes clearance
T14136 330-332 IN denotes of
T14137 333-342 JJ denotes apoptotic
T14138 343-348 NNS denotes cells
T14139 348-350 , denotes ,
T14140 350-351 DT denotes a
T14141 352-359 NN denotes process
T14142 360-364 WDT denotes that
T14143 365-371 VBD denotes proved
T14144 372-374 TO denotes to
T14145 375-377 VB denotes be
T14146 378-384 JJ denotes normal
T14147 385-387 IN denotes in
T14148 388-393 NN denotes Ptdsr
T14150 393-394 HYPH denotes -
T14149 394-403 JJ denotes deficient
T14151 404-408 NNS denotes mice
T14152 408-409 . denotes .
T14153 409-773 sentence denotes This opens up the possibility either that there is an as-yet unknown Ptdsr receptor, which might act as a primary phosphatidylserine recognition receptor, or that recognition of phosphatidylserine and subsequent apoptotic cell engulfment and anti-inflammatory signaling are mainly mediated through phosphatidylserine bridging proteins and their cognate receptors.
T14154 410-414 DT denotes This
T14155 415-420 VBZ denotes opens
T14156 421-423 RP denotes up
T14157 424-427 DT denotes the
T14158 428-439 NN denotes possibility
T14159 440-446 CC denotes either
T14161 447-451 IN denotes that
T14162 452-457 EX denotes there
T14160 458-460 VBZ denotes is
T14163 461-463 DT denotes an
T14165 464-466 RB denotes as
T14167 466-467 HYPH denotes -
T14166 467-470 RB denotes yet
T14168 471-478 JJ denotes unknown
T14169 479-484 NN denotes Ptdsr
T14164 485-493 NN denotes receptor
T14170 493-495 , denotes ,
T14171 495-500 WDT denotes which
T14173 501-506 MD denotes might
T14172 507-510 VB denotes act
T14174 511-513 IN denotes as
T14175 514-515 DT denotes a
T14177 516-523 JJ denotes primary
T14178 524-542 NN denotes phosphatidylserine
T14179 543-554 NN denotes recognition
T14176 555-563 NN denotes receptor
T14180 563-565 , denotes ,
T14181 565-567 CC denotes or
T14182 568-572 IN denotes that
T14184 573-584 NN denotes recognition
T14185 585-587 IN denotes of
T14186 588-606 NN denotes phosphatidylserine
T14187 607-610 CC denotes and
T14188 611-621 JJ denotes subsequent
T14190 622-631 JJ denotes apoptotic
T14191 632-636 NN denotes cell
T14189 637-647 NN denotes engulfment
T14192 648-651 CC denotes and
T14193 652-669 JJ denotes anti-inflammatory
T14194 670-679 NN denotes signaling
T14195 680-683 VBP denotes are
T14196 684-690 RB denotes mainly
T14183 691-699 VBN denotes mediated
T14197 700-707 IN denotes through
T14198 708-726 NN denotes phosphatidylserine
T14200 727-735 NN denotes bridging
T14199 736-744 NN denotes proteins
T14201 745-748 CC denotes and
T14202 749-754 PRP$ denotes their
T14204 755-762 JJ denotes cognate
T14203 763-772 NNS denotes receptors
T14205 772-773 . denotes .
T14206 773-929 sentence denotes Although Ptdsr -/- macrophages were not impaired in their ability to phagocytose apoptotic cells, they showed reduced cytokine responses after stimulation.
T14207 774-782 IN denotes Although
T14209 783-788 NN denotes Ptdsr
T14211 789-790 SYM denotes -
T14212 790-791 HYPH denotes /
T14213 791-792 SYM denotes -
T14210 793-804 NNS denotes macrophages
T14214 805-809 VBD denotes were
T14215 810-813 RB denotes not
T14208 814-822 VBN denotes impaired
T14217 823-825 IN denotes in
T14218 826-831 PRP$ denotes their
T14219 832-839 NN denotes ability
T14220 840-842 TO denotes to
T14221 843-854 VB denotes phagocytose
T14222 855-864 JJ denotes apoptotic
T14223 865-870 NNS denotes cells
T14224 870-872 , denotes ,
T14225 872-876 PRP denotes they
T14216 877-883 VBD denotes showed
T14226 884-891 VBN denotes reduced
T14228 892-900 NN denotes cytokine
T14227 901-910 NNS denotes responses
T14229 911-916 IN denotes after
T14230 917-928 NN denotes stimulation
T14231 928-929 . denotes .
T14232 929-1059 sentence denotes Further work will be required to determine the molecular mechanisms of these newly recognized Ptdsr functions during development.
T14233 930-937 JJ denotes Further
T14234 938-942 NN denotes work
T14236 943-947 MD denotes will
T14237 948-950 VB denotes be
T14235 951-959 VBN denotes required
T14238 960-962 TO denotes to
T14239 963-972 VB denotes determine
T14240 973-976 DT denotes the
T14242 977-986 JJ denotes molecular
T14241 987-997 NNS denotes mechanisms
T14243 998-1000 IN denotes of
T14244 1001-1006 DT denotes these
T14246 1007-1012 RB denotes newly
T14247 1013-1023 VBN denotes recognized
T14248 1024-1029 NN denotes Ptdsr
T14245 1030-1039 NNS denotes functions
T14249 1040-1046 IN denotes during
T14250 1047-1058 NN denotes development
T14251 1058-1059 . denotes .
R8462 T14088 T14089 poss Our,results
R8463 T14089 T14090 nsubj results,demonstrate
R8464 T14091 T14092 mark that,is
R8465 T14092 T14090 ccomp is,demonstrate
R8466 T14093 T14092 nsubj Ptdsr,is
R8467 T14094 T14092 acomp essential,is
R8468 T14095 T14094 prep for,essential
R8469 T14096 T14097 det the,differentiation
R8470 T14097 T14095 pobj differentiation,for
R8471 T14098 T14097 cc and,differentiation
R8472 T14099 T14097 conj maturation,differentiation
R8473 T14100 T14097 prep of,differentiation
R8474 T14101 T14102 amod multiple,tissues
R8475 T14102 T14100 pobj tissues,of
R8476 T14103 T14092 prep during,is
R8477 T14104 T14103 pobj embryogenesis,during
R8478 T14105 T14090 punct .,demonstrate
R8479 T14107 T14108 nsubj Ablation,results
R8480 T14109 T14107 prep of,Ablation
R8481 T14110 T14111 compound Ptdsr,function
R8482 T14111 T14109 pobj function,of
R8483 T14112 T14108 prep in,results
R8484 T14113 T14114 amod neonatal,lethality
R8485 T14114 T14112 pobj lethality,in
R8486 T14115 T14114 cc and,lethality
R8487 T14116 T14117 amod severe,defects
R8488 T14117 T14114 conj defects,lethality
R8489 T14118 T14117 prep in,defects
R8490 T14119 T14120 det the,morphogenesis
R8491 T14120 T14118 pobj morphogenesis,in
R8492 T14121 T14120 prep of,morphogenesis
R8493 T14122 T14123 amod several,organs
R8494 T14123 T14121 pobj organs,of
R8495 T14124 T14108 punct .,results
R8496 T14126 T14127 det The,malformations
R8497 T14127 T14129 nsubjpass malformations,explained
R8498 T14128 T14127 amod developmental,malformations
R8499 T14130 T14129 aux can,explained
R8500 T14131 T14129 neg not,explained
R8501 T14132 T14129 auxpass be,explained
R8502 T14133 T14129 agent by,explained
R8503 T14134 T14135 amod impaired,clearance
R8504 T14135 T14133 pobj clearance,by
R8505 T14136 T14135 prep of,clearance
R8506 T14137 T14138 amod apoptotic,cells
R8507 T14138 T14136 pobj cells,of
R8508 T14139 T14135 punct ", ",clearance
R8509 T14140 T14141 det a,process
R8510 T14141 T14135 appos process,clearance
R8511 T14142 T14143 dep that,proved
R8512 T14143 T14141 relcl proved,process
R8513 T14144 T14145 aux to,be
R8514 T14145 T14143 xcomp be,proved
R8515 T14146 T14145 acomp normal,be
R8516 T14147 T14145 prep in,be
R8517 T14148 T14149 npadvmod Ptdsr,deficient
R8518 T14149 T14151 amod deficient,mice
R8519 T14150 T14149 punct -,deficient
R8520 T14151 T14147 pobj mice,in
R8521 T14152 T14129 punct .,explained
R8522 T14154 T14155 nsubj This,opens
R8523 T14156 T14155 prt up,opens
R8524 T14157 T14158 det the,possibility
R8525 T14158 T14155 dobj possibility,opens
R8526 T14159 T14160 preconj either,is
R8527 T14160 T14158 advcl is,possibility
R8528 T14161 T14160 mark that,is
R8529 T14162 T14160 expl there,is
R8530 T14163 T14164 det an,receptor
R8531 T14164 T14160 attr receptor,is
R8532 T14165 T14166 advmod as,yet
R8533 T14166 T14168 advmod yet,unknown
R8534 T14167 T14166 punct -,yet
R8535 T14168 T14164 amod unknown,receptor
R8536 T14169 T14164 compound Ptdsr,receptor
R8537 T14170 T14164 punct ", ",receptor
R8538 T14171 T14172 dep which,act
R8539 T14172 T14164 relcl act,receptor
R8540 T14173 T14172 aux might,act
R8541 T14174 T14172 prep as,act
R8542 T14175 T14176 det a,receptor
R8543 T14176 T14174 pobj receptor,as
R8544 T14177 T14176 amod primary,receptor
R8545 T14178 T14176 compound phosphatidylserine,receptor
R8546 T14179 T14176 compound recognition,receptor
R8547 T14180 T14160 punct ", ",is
R8548 T14181 T14160 cc or,is
R8549 T14182 T14183 mark that,mediated
R8550 T14183 T14160 conj mediated,is
R8551 T14184 T14183 nsubjpass recognition,mediated
R8552 T14185 T14184 prep of,recognition
R8553 T14186 T14185 pobj phosphatidylserine,of
R8554 T14187 T14184 cc and,recognition
R8555 T14188 T14189 amod subsequent,engulfment
R8556 T14189 T14184 conj engulfment,recognition
R8557 T14190 T14189 amod apoptotic,engulfment
R8558 T14191 T14189 compound cell,engulfment
R8559 T14192 T14189 cc and,engulfment
R8560 T14193 T14194 amod anti-inflammatory,signaling
R8561 T14194 T14189 conj signaling,engulfment
R8562 T14195 T14183 auxpass are,mediated
R8563 T14196 T14183 advmod mainly,mediated
R8564 T14197 T14183 prep through,mediated
R8565 T14198 T14199 compound phosphatidylserine,proteins
R8566 T14199 T14197 pobj proteins,through
R8567 T14200 T14199 compound bridging,proteins
R8568 T14201 T14199 cc and,proteins
R8569 T14202 T14203 poss their,receptors
R8570 T14203 T14199 conj receptors,proteins
R8571 T14204 T14203 amod cognate,receptors
R8572 T14205 T14155 punct .,opens
R8573 T14207 T14208 mark Although,impaired
R8574 T14208 T14216 advcl impaired,showed
R8575 T14209 T14210 nmod Ptdsr,macrophages
R8576 T14210 T14208 nsubjpass macrophages,impaired
R8577 T14211 T14209 punct -,Ptdsr
R8578 T14212 T14209 punct /,Ptdsr
R8579 T14213 T14209 punct -,Ptdsr
R8580 T14214 T14208 auxpass were,impaired
R8581 T14215 T14208 neg not,impaired
R8582 T14217 T14208 prep in,impaired
R8583 T14218 T14219 poss their,ability
R8584 T14219 T14217 pobj ability,in
R8585 T14220 T14221 aux to,phagocytose
R8586 T14221 T14219 acl phagocytose,ability
R8587 T14222 T14223 amod apoptotic,cells
R8588 T14223 T14221 dobj cells,phagocytose
R8589 T14224 T14216 punct ", ",showed
R8590 T14225 T14216 nsubj they,showed
R8591 T14226 T14227 amod reduced,responses
R8592 T14227 T14216 dobj responses,showed
R8593 T14228 T14227 compound cytokine,responses
R8594 T14229 T14216 prep after,showed
R8595 T14230 T14229 pobj stimulation,after
R8596 T14231 T14216 punct .,showed
R8597 T14233 T14234 amod Further,work
R8598 T14234 T14235 nsubjpass work,required
R8599 T14236 T14235 aux will,required
R8600 T14237 T14235 auxpass be,required
R8601 T14238 T14239 aux to,determine
R8602 T14239 T14235 advcl determine,required
R8603 T14240 T14241 det the,mechanisms
R8604 T14241 T14239 dobj mechanisms,determine
R8605 T14242 T14241 amod molecular,mechanisms
R8606 T14243 T14241 prep of,mechanisms
R8607 T14244 T14245 det these,functions
R8608 T14245 T14243 pobj functions,of
R8609 T14246 T14247 advmod newly,recognized
R8610 T14247 T14245 amod recognized,functions
R8611 T14248 T14245 compound Ptdsr,functions
R8612 T14249 T14241 prep during,mechanisms
R8613 T14250 T14249 pobj development,during
R8614 T14251 T14235 punct .,required