Id |
Subject |
Object |
Predicate |
Lexical cue |
T8339 |
0-5 |
NN |
denotes |
Ptdsr |
T8341 |
5-6 |
HYPH |
denotes |
- |
T8340 |
6-16 |
NN |
denotes |
deficiency |
T8342 |
17-24 |
VBZ |
denotes |
results |
T8343 |
25-27 |
IN |
denotes |
in |
T8344 |
28-35 |
VBN |
denotes |
reduced |
T8345 |
36-46 |
NN |
denotes |
production |
T8346 |
47-49 |
IN |
denotes |
of |
T8347 |
50-53 |
JJ |
denotes |
pro |
T8349 |
53-54 |
HYPH |
denotes |
- |
T8350 |
55-58 |
CC |
denotes |
and |
T8351 |
59-76 |
JJ |
denotes |
anti-inflammatory |
T8348 |
77-86 |
NNS |
denotes |
cytokines |
T8352 |
87-92 |
IN |
denotes |
after |
T8353 |
93-103 |
NN |
denotes |
macrophage |
T8354 |
104-115 |
NN |
denotes |
stimulation |
T8355 |
115-376 |
sentence |
denotes |
In addition to its suggested importance for phagocytosis of apoptotic cells, it has been proposed that Ptdsr fulfils a second crucial role in regulating and maintaining a non-inflammatory environment upon the recognition of apoptotic cells by macrophages [26]. |
T8356 |
116-118 |
IN |
denotes |
In |
T8358 |
119-127 |
NN |
denotes |
addition |
T8359 |
128-130 |
IN |
denotes |
to |
T8360 |
131-134 |
PRP$ |
denotes |
its |
T8362 |
135-144 |
JJ |
denotes |
suggested |
T8361 |
145-155 |
NN |
denotes |
importance |
T8363 |
156-159 |
IN |
denotes |
for |
T8364 |
160-172 |
NN |
denotes |
phagocytosis |
T8365 |
173-175 |
IN |
denotes |
of |
T8366 |
176-185 |
JJ |
denotes |
apoptotic |
T8367 |
186-191 |
NNS |
denotes |
cells |
T8368 |
191-193 |
, |
denotes |
, |
T8369 |
193-195 |
PRP |
denotes |
it |
T8370 |
196-199 |
VBZ |
denotes |
has |
T8371 |
200-204 |
VBN |
denotes |
been |
T8357 |
205-213 |
VBN |
denotes |
proposed |
T8372 |
214-218 |
IN |
denotes |
that |
T8374 |
219-224 |
NN |
denotes |
Ptdsr |
T8373 |
225-232 |
VBZ |
denotes |
fulfils |
T8375 |
233-234 |
DT |
denotes |
a |
T8377 |
235-241 |
JJ |
denotes |
second |
T8378 |
242-249 |
JJ |
denotes |
crucial |
T8376 |
250-254 |
NN |
denotes |
role |
T8379 |
255-257 |
IN |
denotes |
in |
T8380 |
258-268 |
VBG |
denotes |
regulating |
T8381 |
269-272 |
CC |
denotes |
and |
T8382 |
273-284 |
VBG |
denotes |
maintaining |
T8383 |
285-286 |
DT |
denotes |
a |
T8385 |
287-303 |
JJ |
denotes |
non-inflammatory |
T8384 |
304-315 |
NN |
denotes |
environment |
T8386 |
316-320 |
IN |
denotes |
upon |
T8387 |
321-324 |
DT |
denotes |
the |
T8388 |
325-336 |
NN |
denotes |
recognition |
T8389 |
337-339 |
IN |
denotes |
of |
T8390 |
340-349 |
JJ |
denotes |
apoptotic |
T8391 |
350-355 |
NNS |
denotes |
cells |
T8392 |
356-358 |
IN |
denotes |
by |
T8393 |
359-370 |
NNS |
denotes |
macrophages |
T8394 |
371-372 |
-LRB- |
denotes |
[ |
T8395 |
372-374 |
CD |
denotes |
26 |
T8396 |
374-375 |
-RRB- |
denotes |
] |
T8397 |
375-376 |
. |
denotes |
. |
T8398 |
376-511 |
sentence |
denotes |
We therefore tested whether Ptdsr -/- macrophages were able to release anti-inflammatory cytokines after ingestion of apoptotic cells. |
T8399 |
377-379 |
PRP |
denotes |
We |
T8401 |
380-389 |
RB |
denotes |
therefore |
T8400 |
390-396 |
VBD |
denotes |
tested |
T8402 |
397-404 |
IN |
denotes |
whether |
T8404 |
405-410 |
NN |
denotes |
Ptdsr |
T8406 |
411-412 |
SYM |
denotes |
- |
T8407 |
412-413 |
HYPH |
denotes |
/ |
T8408 |
413-414 |
SYM |
denotes |
- |
T8405 |
415-426 |
NNS |
denotes |
macrophages |
T8403 |
427-431 |
VBD |
denotes |
were |
T8409 |
432-436 |
JJ |
denotes |
able |
T8410 |
437-439 |
TO |
denotes |
to |
T8411 |
440-447 |
VB |
denotes |
release |
T8412 |
448-465 |
JJ |
denotes |
anti-inflammatory |
T8413 |
466-475 |
NNS |
denotes |
cytokines |
T8414 |
476-481 |
IN |
denotes |
after |
T8415 |
482-491 |
NN |
denotes |
ingestion |
T8416 |
492-494 |
IN |
denotes |
of |
T8417 |
495-504 |
JJ |
denotes |
apoptotic |
T8418 |
505-510 |
NNS |
denotes |
cells |
T8419 |
510-511 |
. |
denotes |
. |
T8420 |
511-673 |
sentence |
denotes |
We examined levels of TGF-β1 and interleukin-10 (IL-10) after stimulation of FLDMs with lipopolysaccharide (LPS), with and without co-culture of apoptotic cells. |
T8421 |
512-514 |
PRP |
denotes |
We |
T8422 |
515-523 |
VBD |
denotes |
examined |
T8423 |
524-530 |
NNS |
denotes |
levels |
T8424 |
531-533 |
IN |
denotes |
of |
T8425 |
534-537 |
NN |
denotes |
TGF |
T8427 |
537-538 |
HYPH |
denotes |
- |
T8426 |
538-540 |
NN |
denotes |
β1 |
T8428 |
541-544 |
CC |
denotes |
and |
T8429 |
545-556 |
NN |
denotes |
interleukin |
T8430 |
556-557 |
HYPH |
denotes |
- |
T8431 |
557-559 |
CD |
denotes |
10 |
T8432 |
560-561 |
-LRB- |
denotes |
( |
T8433 |
561-563 |
NN |
denotes |
IL |
T8434 |
563-564 |
HYPH |
denotes |
- |
T8435 |
564-566 |
CD |
denotes |
10 |
T8436 |
566-567 |
-RRB- |
denotes |
) |
T8437 |
568-573 |
IN |
denotes |
after |
T8438 |
574-585 |
NN |
denotes |
stimulation |
T8439 |
586-588 |
IN |
denotes |
of |
T8440 |
589-594 |
NNS |
denotes |
FLDMs |
T8441 |
595-599 |
IN |
denotes |
with |
T8442 |
600-618 |
NN |
denotes |
lipopolysaccharide |
T8443 |
619-620 |
-LRB- |
denotes |
( |
T8444 |
620-623 |
NN |
denotes |
LPS |
T8445 |
623-624 |
-RRB- |
denotes |
) |
T8446 |
624-626 |
, |
denotes |
, |
T8447 |
626-630 |
IN |
denotes |
with |
T8448 |
631-634 |
CC |
denotes |
and |
T8449 |
635-642 |
IN |
denotes |
without |
T8450 |
643-653 |
NN |
denotes |
co-culture |
T8451 |
654-656 |
IN |
denotes |
of |
T8452 |
657-666 |
JJ |
denotes |
apoptotic |
T8453 |
667-672 |
NNS |
denotes |
cells |
T8454 |
672-673 |
. |
denotes |
. |
T8455 |
673-936 |
sentence |
denotes |
Quantification of TGF-β1 and IL-10 levels after 22 hours of culture demonstrated that Ptdsr -/- macrophages were able to secrete these anti-inflammatory cytokines upon ingestion of apoptotic cells, although at a slightly lower level than wild-type (Figure 8a,b). |
T8456 |
674-688 |
NN |
denotes |
Quantification |
T8458 |
689-691 |
IN |
denotes |
of |
T8459 |
692-695 |
NN |
denotes |
TGF |
T8461 |
695-696 |
HYPH |
denotes |
- |
T8460 |
696-698 |
NN |
denotes |
β1 |
T8463 |
699-702 |
CC |
denotes |
and |
T8464 |
703-705 |
NN |
denotes |
IL |
T8465 |
705-706 |
HYPH |
denotes |
- |
T8466 |
706-708 |
CD |
denotes |
10 |
T8462 |
709-715 |
NNS |
denotes |
levels |
T8467 |
716-721 |
IN |
denotes |
after |
T8468 |
722-724 |
CD |
denotes |
22 |
T8469 |
725-730 |
NNS |
denotes |
hours |
T8470 |
731-733 |
IN |
denotes |
of |
T8471 |
734-741 |
NN |
denotes |
culture |
T8457 |
742-754 |
VBD |
denotes |
demonstrated |
T8472 |
755-759 |
IN |
denotes |
that |
T8474 |
760-765 |
NN |
denotes |
Ptdsr |
T8476 |
766-767 |
SYM |
denotes |
- |
T8477 |
767-768 |
HYPH |
denotes |
/ |
T8478 |
768-769 |
SYM |
denotes |
- |
T8475 |
770-781 |
NNS |
denotes |
macrophages |
T8473 |
782-786 |
VBD |
denotes |
were |
T8479 |
787-791 |
JJ |
denotes |
able |
T8480 |
792-794 |
TO |
denotes |
to |
T8481 |
795-802 |
VB |
denotes |
secrete |
T8482 |
803-808 |
DT |
denotes |
these |
T8484 |
809-826 |
JJ |
denotes |
anti-inflammatory |
T8483 |
827-836 |
NNS |
denotes |
cytokines |
T8485 |
837-841 |
IN |
denotes |
upon |
T8486 |
842-851 |
NN |
denotes |
ingestion |
T8487 |
852-854 |
IN |
denotes |
of |
T8488 |
855-864 |
JJ |
denotes |
apoptotic |
T8489 |
865-870 |
NNS |
denotes |
cells |
T8490 |
870-872 |
, |
denotes |
, |
T8491 |
872-880 |
IN |
denotes |
although |
T8492 |
881-883 |
IN |
denotes |
at |
T8493 |
884-885 |
DT |
denotes |
a |
T8495 |
886-894 |
RB |
denotes |
slightly |
T8496 |
895-900 |
JJR |
denotes |
lower |
T8494 |
901-906 |
NN |
denotes |
level |
T8497 |
907-911 |
IN |
denotes |
than |
T8498 |
912-916 |
JJ |
denotes |
wild |
T8500 |
916-917 |
HYPH |
denotes |
- |
T8499 |
917-921 |
NN |
denotes |
type |
T8501 |
922-923 |
-LRB- |
denotes |
( |
T8503 |
923-929 |
NN |
denotes |
Figure |
T8504 |
930-932 |
NN |
denotes |
8a |
T8505 |
932-933 |
, |
denotes |
, |
T8502 |
933-934 |
NN |
denotes |
b |
T8506 |
934-935 |
-RRB- |
denotes |
) |
T8507 |
935-936 |
. |
denotes |
. |
T8508 |
936-1134 |
sentence |
denotes |
This indicates that ablation of Ptdsr function does not compromise in general the ability of macrophages to release immune-suppressive cytokines after recognition and engulfment of apoptotic cells. |
T8509 |
937-941 |
DT |
denotes |
This |
T8510 |
942-951 |
VBZ |
denotes |
indicates |
T8511 |
952-956 |
IN |
denotes |
that |
T8513 |
957-965 |
NN |
denotes |
ablation |
T8514 |
966-968 |
IN |
denotes |
of |
T8515 |
969-974 |
NN |
denotes |
Ptdsr |
T8516 |
975-983 |
NN |
denotes |
function |
T8517 |
984-988 |
VBZ |
denotes |
does |
T8518 |
989-992 |
RB |
denotes |
not |
T8512 |
993-1003 |
VB |
denotes |
compromise |
T8519 |
1004-1006 |
IN |
denotes |
in |
T8520 |
1007-1014 |
JJ |
denotes |
general |
T8521 |
1015-1018 |
DT |
denotes |
the |
T8522 |
1019-1026 |
NN |
denotes |
ability |
T8523 |
1027-1029 |
IN |
denotes |
of |
T8524 |
1030-1041 |
NNS |
denotes |
macrophages |
T8525 |
1042-1044 |
TO |
denotes |
to |
T8526 |
1045-1052 |
VB |
denotes |
release |
T8527 |
1053-1059 |
NN |
denotes |
immune |
T8529 |
1059-1060 |
HYPH |
denotes |
- |
T8528 |
1060-1071 |
JJ |
denotes |
suppressive |
T8530 |
1072-1081 |
NNS |
denotes |
cytokines |
T8531 |
1082-1087 |
IN |
denotes |
after |
T8532 |
1088-1099 |
NN |
denotes |
recognition |
T8533 |
1100-1103 |
CC |
denotes |
and |
T8534 |
1104-1114 |
NN |
denotes |
engulfment |
T8535 |
1115-1117 |
IN |
denotes |
of |
T8536 |
1118-1127 |
JJ |
denotes |
apoptotic |
T8537 |
1128-1133 |
NNS |
denotes |
cells |
T8538 |
1133-1134 |
. |
denotes |
. |
T8539 |
1134-1391 |
sentence |
denotes |
To analyze whether pro-inflammatory signaling is affected in Ptdsr -/- macrophages, we stimulated FLDMs from Ptdsr+/+ and Ptdsr -/- mice with LPS and measured levels of tumor necrosis factor-α (TNF-α) at different time points after stimulation (Figure 8c). |
T8540 |
1135-1137 |
TO |
denotes |
To |
T8541 |
1138-1145 |
VB |
denotes |
analyze |
T8543 |
1146-1153 |
IN |
denotes |
whether |
T8545 |
1154-1170 |
JJ |
denotes |
pro-inflammatory |
T8546 |
1171-1180 |
NN |
denotes |
signaling |
T8547 |
1181-1183 |
VBZ |
denotes |
is |
T8544 |
1184-1192 |
VBN |
denotes |
affected |
T8548 |
1193-1195 |
IN |
denotes |
in |
T8549 |
1196-1201 |
NN |
denotes |
Ptdsr |
T8551 |
1202-1203 |
SYM |
denotes |
- |
T8552 |
1203-1204 |
HYPH |
denotes |
/ |
T8553 |
1204-1205 |
SYM |
denotes |
- |
T8550 |
1206-1217 |
NNS |
denotes |
macrophages |
T8554 |
1217-1219 |
, |
denotes |
, |
T8555 |
1219-1221 |
PRP |
denotes |
we |
T8542 |
1222-1232 |
VBD |
denotes |
stimulated |
T8556 |
1233-1238 |
NNS |
denotes |
FLDMs |
T8557 |
1239-1243 |
IN |
denotes |
from |
T8558 |
1244-1249 |
NN |
denotes |
Ptdsr |
T8560 |
1249-1250 |
SYM |
denotes |
+ |
T8561 |
1250-1251 |
HYPH |
denotes |
/ |
T8562 |
1251-1252 |
SYM |
denotes |
+ |
T8563 |
1253-1256 |
CC |
denotes |
and |
T8564 |
1257-1262 |
NN |
denotes |
Ptdsr |
T8565 |
1263-1264 |
SYM |
denotes |
- |
T8566 |
1264-1265 |
HYPH |
denotes |
/ |
T8567 |
1265-1266 |
SYM |
denotes |
- |
T8559 |
1267-1271 |
NNS |
denotes |
mice |
T8568 |
1272-1276 |
IN |
denotes |
with |
T8569 |
1277-1280 |
NN |
denotes |
LPS |
T8570 |
1281-1284 |
CC |
denotes |
and |
T8571 |
1285-1293 |
VBD |
denotes |
measured |
T8572 |
1294-1300 |
NNS |
denotes |
levels |
T8573 |
1301-1303 |
IN |
denotes |
of |
T8574 |
1304-1309 |
NN |
denotes |
tumor |
T8576 |
1310-1318 |
NN |
denotes |
necrosis |
T8577 |
1319-1325 |
NN |
denotes |
factor |
T8578 |
1325-1326 |
HYPH |
denotes |
- |
T8575 |
1326-1327 |
NN |
denotes |
α |
T8579 |
1328-1329 |
-LRB- |
denotes |
( |
T8581 |
1329-1332 |
NN |
denotes |
TNF |
T8582 |
1332-1333 |
HYPH |
denotes |
- |
T8580 |
1333-1334 |
NN |
denotes |
α |
T8583 |
1334-1335 |
-RRB- |
denotes |
) |
T8584 |
1336-1338 |
IN |
denotes |
at |
T8585 |
1339-1348 |
JJ |
denotes |
different |
T8587 |
1349-1353 |
NN |
denotes |
time |
T8586 |
1354-1360 |
NNS |
denotes |
points |
T8588 |
1361-1366 |
IN |
denotes |
after |
T8589 |
1367-1378 |
NN |
denotes |
stimulation |
T8590 |
1379-1380 |
-LRB- |
denotes |
( |
T8592 |
1380-1386 |
NN |
denotes |
Figure |
T8591 |
1387-1389 |
NN |
denotes |
8c |
T8593 |
1389-1390 |
-RRB- |
denotes |
) |
T8594 |
1390-1391 |
. |
denotes |
. |
T8595 |
1391-1479 |
sentence |
denotes |
Ptdsr -/- macrophages produced significantly less TNF-α than did wild-type macrophages. |
T8596 |
1392-1397 |
NN |
denotes |
Ptdsr |
T8598 |
1398-1399 |
SYM |
denotes |
- |
T8599 |
1399-1400 |
HYPH |
denotes |
/ |
T8600 |
1400-1401 |
SYM |
denotes |
- |
T8597 |
1402-1413 |
NNS |
denotes |
macrophages |
T8601 |
1414-1422 |
VBD |
denotes |
produced |
T8602 |
1423-1436 |
RB |
denotes |
significantly |
T8603 |
1437-1441 |
JJR |
denotes |
less |
T8605 |
1442-1445 |
NN |
denotes |
TNF |
T8606 |
1445-1446 |
HYPH |
denotes |
- |
T8604 |
1446-1447 |
NN |
denotes |
α |
T8607 |
1448-1452 |
IN |
denotes |
than |
T8608 |
1453-1456 |
VBD |
denotes |
did |
T8609 |
1457-1461 |
JJ |
denotes |
wild |
T8611 |
1461-1462 |
HYPH |
denotes |
- |
T8610 |
1462-1466 |
NN |
denotes |
type |
T8612 |
1467-1478 |
NNS |
denotes |
macrophages |
T8613 |
1478-1479 |
. |
denotes |
. |
T8614 |
1479-1687 |
sentence |
denotes |
The difference in TNF-α secretion was first visible after 3 h of LPS stimulation and became more prominent during the course of the experiment (for example, after 9 h and 12 h of LPS stimulation; Figure 8c). |
T8615 |
1480-1483 |
DT |
denotes |
The |
T8616 |
1484-1494 |
NN |
denotes |
difference |
T8618 |
1495-1497 |
IN |
denotes |
in |
T8619 |
1498-1501 |
NN |
denotes |
TNF |
T8621 |
1501-1502 |
HYPH |
denotes |
- |
T8620 |
1502-1503 |
NN |
denotes |
α |
T8622 |
1504-1513 |
NN |
denotes |
secretion |
T8617 |
1514-1517 |
VBD |
denotes |
was |
T8623 |
1518-1523 |
RB |
denotes |
first |
T8624 |
1524-1531 |
JJ |
denotes |
visible |
T8625 |
1532-1537 |
IN |
denotes |
after |
T8626 |
1538-1539 |
CD |
denotes |
3 |
T8627 |
1540-1541 |
NNS |
denotes |
h |
T8628 |
1542-1544 |
IN |
denotes |
of |
T8629 |
1545-1548 |
NN |
denotes |
LPS |
T8630 |
1549-1560 |
NN |
denotes |
stimulation |
T8631 |
1561-1564 |
CC |
denotes |
and |
T8632 |
1565-1571 |
VBD |
denotes |
became |
T8633 |
1572-1576 |
RBR |
denotes |
more |
T8634 |
1577-1586 |
JJ |
denotes |
prominent |
T8635 |
1587-1593 |
IN |
denotes |
during |
T8636 |
1594-1597 |
DT |
denotes |
the |
T8637 |
1598-1604 |
NN |
denotes |
course |
T8638 |
1605-1607 |
IN |
denotes |
of |
T8639 |
1608-1611 |
DT |
denotes |
the |
T8640 |
1612-1622 |
NN |
denotes |
experiment |
T8641 |
1623-1624 |
-LRB- |
denotes |
( |
T8643 |
1624-1627 |
IN |
denotes |
for |
T8644 |
1628-1635 |
NN |
denotes |
example |
T8645 |
1635-1637 |
, |
denotes |
, |
T8646 |
1637-1642 |
IN |
denotes |
after |
T8647 |
1643-1644 |
CD |
denotes |
9 |
T8648 |
1645-1646 |
NNS |
denotes |
h |
T8649 |
1647-1650 |
CC |
denotes |
and |
T8650 |
1651-1653 |
CD |
denotes |
12 |
T8651 |
1654-1655 |
NNS |
denotes |
h |
T8652 |
1656-1658 |
IN |
denotes |
of |
T8653 |
1659-1662 |
NN |
denotes |
LPS |
T8654 |
1663-1674 |
NN |
denotes |
stimulation |
T8655 |
1674-1675 |
: |
denotes |
; |
T8656 |
1676-1682 |
NN |
denotes |
Figure |
T8642 |
1683-1685 |
NN |
denotes |
8c |
T8657 |
1685-1686 |
-RRB- |
denotes |
) |
T8658 |
1686-1687 |
. |
denotes |
. |
T8659 |
1687-1850 |
sentence |
denotes |
To analyze whether TNF-α release by Ptdsr -/- macrophages can be affected by engulfment of apoptotic cells, we stimulated FLDMs with LPS, apoptotic cells or both. |
T8660 |
1688-1690 |
TO |
denotes |
To |
T8661 |
1691-1698 |
VB |
denotes |
analyze |
T8663 |
1699-1706 |
IN |
denotes |
whether |
T8665 |
1707-1710 |
NN |
denotes |
TNF |
T8667 |
1710-1711 |
HYPH |
denotes |
- |
T8666 |
1711-1712 |
NN |
denotes |
α |
T8668 |
1713-1720 |
NN |
denotes |
release |
T8669 |
1721-1723 |
IN |
denotes |
by |
T8670 |
1724-1729 |
NN |
denotes |
Ptdsr |
T8672 |
1730-1731 |
SYM |
denotes |
- |
T8673 |
1731-1732 |
HYPH |
denotes |
/ |
T8674 |
1732-1733 |
SYM |
denotes |
- |
T8671 |
1734-1745 |
NNS |
denotes |
macrophages |
T8675 |
1746-1749 |
MD |
denotes |
can |
T8676 |
1750-1752 |
VB |
denotes |
be |
T8664 |
1753-1761 |
VBN |
denotes |
affected |
T8677 |
1762-1764 |
IN |
denotes |
by |
T8678 |
1765-1775 |
NN |
denotes |
engulfment |
T8679 |
1776-1778 |
IN |
denotes |
of |
T8680 |
1779-1788 |
JJ |
denotes |
apoptotic |
T8681 |
1789-1794 |
NNS |
denotes |
cells |
T8682 |
1794-1796 |
, |
denotes |
, |
T8683 |
1796-1798 |
PRP |
denotes |
we |
T8662 |
1799-1809 |
VBD |
denotes |
stimulated |
T8684 |
1810-1815 |
NNS |
denotes |
FLDMs |
T8685 |
1816-1820 |
IN |
denotes |
with |
T8686 |
1821-1824 |
NN |
denotes |
LPS |
T8687 |
1824-1826 |
, |
denotes |
, |
T8688 |
1826-1835 |
JJ |
denotes |
apoptotic |
T8689 |
1836-1841 |
NNS |
denotes |
cells |
T8690 |
1842-1844 |
CC |
denotes |
or |
T8691 |
1845-1849 |
DT |
denotes |
both |
T8692 |
1849-1850 |
. |
denotes |
. |
T8693 |
1850-2085 |
sentence |
denotes |
Quantification of TNF-α levels by ELISA after 22 h showed that Ptdsr-deficient macrophages release less TNF-α after stimulation with LPS alone, and also after double stimulation of macrophages with LPS and apoptotic cells (Figure 8d). |
T8694 |
1851-1865 |
NN |
denotes |
Quantification |
T8696 |
1866-1868 |
IN |
denotes |
of |
T8697 |
1869-1872 |
NN |
denotes |
TNF |
T8699 |
1872-1873 |
HYPH |
denotes |
- |
T8698 |
1873-1874 |
NN |
denotes |
α |
T8700 |
1875-1881 |
NNS |
denotes |
levels |
T8701 |
1882-1884 |
IN |
denotes |
by |
T8702 |
1885-1890 |
NN |
denotes |
ELISA |
T8703 |
1891-1896 |
IN |
denotes |
after |
T8704 |
1897-1899 |
CD |
denotes |
22 |
T8705 |
1900-1901 |
NN |
denotes |
h |
T8695 |
1902-1908 |
VBD |
denotes |
showed |
T8706 |
1909-1913 |
IN |
denotes |
that |
T8708 |
1914-1919 |
NN |
denotes |
Ptdsr |
T8710 |
1919-1920 |
HYPH |
denotes |
- |
T8709 |
1920-1929 |
JJ |
denotes |
deficient |
T8711 |
1930-1941 |
NNS |
denotes |
macrophages |
T8707 |
1942-1949 |
VBP |
denotes |
release |
T8712 |
1950-1954 |
JJR |
denotes |
less |
T8714 |
1955-1958 |
NN |
denotes |
TNF |
T8715 |
1958-1959 |
HYPH |
denotes |
- |
T8713 |
1959-1960 |
NN |
denotes |
α |
T8716 |
1961-1966 |
IN |
denotes |
after |
T8717 |
1967-1978 |
NN |
denotes |
stimulation |
T8718 |
1979-1983 |
IN |
denotes |
with |
T8719 |
1984-1987 |
NN |
denotes |
LPS |
T8720 |
1988-1993 |
RB |
denotes |
alone |
T8721 |
1993-1995 |
, |
denotes |
, |
T8722 |
1995-1998 |
CC |
denotes |
and |
T8723 |
1999-2003 |
RB |
denotes |
also |
T8724 |
2004-2009 |
IN |
denotes |
after |
T8725 |
2010-2016 |
JJ |
denotes |
double |
T8726 |
2017-2028 |
NN |
denotes |
stimulation |
T8727 |
2029-2031 |
IN |
denotes |
of |
T8728 |
2032-2043 |
NNS |
denotes |
macrophages |
T8729 |
2044-2048 |
IN |
denotes |
with |
T8730 |
2049-2052 |
NN |
denotes |
LPS |
T8731 |
2053-2056 |
CC |
denotes |
and |
T8732 |
2057-2066 |
JJ |
denotes |
apoptotic |
T8733 |
2067-2072 |
NNS |
denotes |
cells |
T8734 |
2073-2074 |
-LRB- |
denotes |
( |
T8736 |
2074-2080 |
NN |
denotes |
Figure |
T8735 |
2081-2083 |
NN |
denotes |
8d |
T8737 |
2083-2084 |
-RRB- |
denotes |
) |
T8738 |
2084-2085 |
. |
denotes |
. |
T8739 |
2085-2313 |
sentence |
denotes |
Moreover, the double stimulation demonstrated that the LPS-induced TNF-α release by Ptdsr -/- macrophages could be inhibited by co-administration of apoptotic cells to an extent comparable to that seen in wild-type macrophages. |
T8740 |
2086-2094 |
RB |
denotes |
Moreover |
T8742 |
2094-2096 |
, |
denotes |
, |
T8743 |
2096-2099 |
DT |
denotes |
the |
T8745 |
2100-2106 |
JJ |
denotes |
double |
T8744 |
2107-2118 |
NN |
denotes |
stimulation |
T8741 |
2119-2131 |
VBD |
denotes |
demonstrated |
T8746 |
2132-2136 |
IN |
denotes |
that |
T8748 |
2137-2140 |
DT |
denotes |
the |
T8750 |
2141-2144 |
NN |
denotes |
LPS |
T8752 |
2144-2145 |
HYPH |
denotes |
- |
T8751 |
2145-2152 |
VBN |
denotes |
induced |
T8753 |
2153-2156 |
NN |
denotes |
TNF |
T8755 |
2156-2157 |
HYPH |
denotes |
- |
T8754 |
2157-2158 |
NN |
denotes |
α |
T8749 |
2159-2166 |
NN |
denotes |
release |
T8756 |
2167-2169 |
IN |
denotes |
by |
T8757 |
2170-2175 |
NN |
denotes |
Ptdsr |
T8759 |
2176-2177 |
SYM |
denotes |
- |
T8760 |
2177-2178 |
HYPH |
denotes |
/ |
T8761 |
2178-2179 |
SYM |
denotes |
- |
T8758 |
2180-2191 |
NNS |
denotes |
macrophages |
T8762 |
2192-2197 |
MD |
denotes |
could |
T8763 |
2198-2200 |
VB |
denotes |
be |
T8747 |
2201-2210 |
VBN |
denotes |
inhibited |
T8764 |
2211-2213 |
IN |
denotes |
by |
T8765 |
2214-2231 |
NN |
denotes |
co-administration |
T8766 |
2232-2234 |
IN |
denotes |
of |
T8767 |
2235-2244 |
JJ |
denotes |
apoptotic |
T8768 |
2245-2250 |
NNS |
denotes |
cells |
T8769 |
2251-2253 |
IN |
denotes |
to |
T8770 |
2254-2256 |
DT |
denotes |
an |
T8771 |
2257-2263 |
NN |
denotes |
extent |
T8772 |
2264-2274 |
JJ |
denotes |
comparable |
T8773 |
2275-2277 |
IN |
denotes |
to |
T8774 |
2278-2282 |
DT |
denotes |
that |
T8775 |
2283-2287 |
VBN |
denotes |
seen |
T8776 |
2288-2290 |
IN |
denotes |
in |
T8777 |
2291-2295 |
JJ |
denotes |
wild |
T8779 |
2295-2296 |
HYPH |
denotes |
- |
T8778 |
2296-2300 |
NN |
denotes |
type |
T8780 |
2301-2312 |
NNS |
denotes |
macrophages |
T8781 |
2312-2313 |
. |
denotes |
. |
T8782 |
2313-2476 |
sentence |
denotes |
Similar results were obtained when other pro-inflammatory cytokines, such as interleukin-6 and monocyte chemoattractant protein-1, were analyzed (data not shown). |
T8783 |
2314-2321 |
JJ |
denotes |
Similar |
T8784 |
2322-2329 |
NNS |
denotes |
results |
T8786 |
2330-2334 |
VBD |
denotes |
were |
T8785 |
2335-2343 |
VBN |
denotes |
obtained |
T8787 |
2344-2348 |
WRB |
denotes |
when |
T8789 |
2349-2354 |
JJ |
denotes |
other |
T8791 |
2355-2371 |
JJ |
denotes |
pro-inflammatory |
T8790 |
2372-2381 |
NNS |
denotes |
cytokines |
T8792 |
2381-2383 |
, |
denotes |
, |
T8793 |
2383-2387 |
JJ |
denotes |
such |
T8794 |
2388-2390 |
IN |
denotes |
as |
T8795 |
2391-2402 |
NN |
denotes |
interleukin |
T8796 |
2402-2403 |
HYPH |
denotes |
- |
T8797 |
2403-2404 |
CD |
denotes |
6 |
T8798 |
2405-2408 |
CC |
denotes |
and |
T8799 |
2409-2417 |
NN |
denotes |
monocyte |
T8801 |
2418-2433 |
NN |
denotes |
chemoattractant |
T8800 |
2434-2441 |
NN |
denotes |
protein |
T8802 |
2441-2442 |
HYPH |
denotes |
- |
T8803 |
2442-2443 |
CD |
denotes |
1 |
T8804 |
2443-2445 |
, |
denotes |
, |
T8805 |
2445-2449 |
VBD |
denotes |
were |
T8788 |
2450-2458 |
VBN |
denotes |
analyzed |
T8806 |
2459-2460 |
-LRB- |
denotes |
( |
T8808 |
2460-2464 |
NNS |
denotes |
data |
T8809 |
2465-2468 |
RB |
denotes |
not |
T8807 |
2469-2474 |
VBN |
denotes |
shown |
T8810 |
2474-2475 |
-RRB- |
denotes |
) |
T8811 |
2475-2476 |
. |
denotes |
. |
T8812 |
2476-2643 |
sentence |
denotes |
These results indicate that Ptdsr is not required in macrophages for the inhibition of pro-inflammatory signaling after recognition and engulfment of apoptotic cells. |
T8813 |
2477-2482 |
DT |
denotes |
These |
T8814 |
2483-2490 |
NNS |
denotes |
results |
T8815 |
2491-2499 |
VBP |
denotes |
indicate |
T8816 |
2500-2504 |
IN |
denotes |
that |
T8818 |
2505-2510 |
NN |
denotes |
Ptdsr |
T8819 |
2511-2513 |
VBZ |
denotes |
is |
T8820 |
2514-2517 |
RB |
denotes |
not |
T8817 |
2518-2526 |
VBN |
denotes |
required |
T8821 |
2527-2529 |
IN |
denotes |
in |
T8822 |
2530-2541 |
NNS |
denotes |
macrophages |
T8823 |
2542-2545 |
IN |
denotes |
for |
T8824 |
2546-2549 |
DT |
denotes |
the |
T8825 |
2550-2560 |
NN |
denotes |
inhibition |
T8826 |
2561-2563 |
IN |
denotes |
of |
T8827 |
2564-2580 |
JJ |
denotes |
pro-inflammatory |
T8828 |
2581-2590 |
NN |
denotes |
signaling |
T8829 |
2591-2596 |
IN |
denotes |
after |
T8830 |
2597-2608 |
NN |
denotes |
recognition |
T8831 |
2609-2612 |
CC |
denotes |
and |
T8832 |
2613-2623 |
NN |
denotes |
engulfment |
T8833 |
2624-2626 |
IN |
denotes |
of |
T8834 |
2627-2636 |
JJ |
denotes |
apoptotic |
T8835 |
2637-2642 |
NNS |
denotes |
cells |
T8836 |
2642-2643 |
. |
denotes |
. |
T8837 |
2643-2954 |
sentence |
denotes |
Ptdsr-deficiency does, however, affect the overall release of pro- and anti-inflammatory cytokines after stimulation with LPS and after double treatment with LPS and apoptotic cells, indicating that Ptdsr-deficient macrophages have a reduced capacity to produce or secrete pro- and anti-inflammatory cytokines. |
T8838 |
2644-2649 |
NN |
denotes |
Ptdsr |
T8840 |
2649-2650 |
HYPH |
denotes |
- |
T8839 |
2650-2660 |
NN |
denotes |
deficiency |
T8842 |
2661-2665 |
VBZ |
denotes |
does |
T8843 |
2665-2667 |
, |
denotes |
, |
T8844 |
2667-2674 |
RB |
denotes |
however |
T8845 |
2674-2676 |
, |
denotes |
, |
T8841 |
2676-2682 |
VB |
denotes |
affect |
T8846 |
2683-2686 |
DT |
denotes |
the |
T8848 |
2687-2694 |
JJ |
denotes |
overall |
T8847 |
2695-2702 |
NN |
denotes |
release |
T8849 |
2703-2705 |
IN |
denotes |
of |
T8850 |
2706-2709 |
JJ |
denotes |
pro |
T8852 |
2709-2710 |
HYPH |
denotes |
- |
T8853 |
2711-2714 |
CC |
denotes |
and |
T8854 |
2715-2732 |
JJ |
denotes |
anti-inflammatory |
T8851 |
2733-2742 |
NNS |
denotes |
cytokines |
T8855 |
2743-2748 |
IN |
denotes |
after |
T8856 |
2749-2760 |
NN |
denotes |
stimulation |
T8857 |
2761-2765 |
IN |
denotes |
with |
T8858 |
2766-2769 |
NN |
denotes |
LPS |
T8859 |
2770-2773 |
CC |
denotes |
and |
T8860 |
2774-2779 |
IN |
denotes |
after |
T8861 |
2780-2786 |
JJ |
denotes |
double |
T8862 |
2787-2796 |
NN |
denotes |
treatment |
T8863 |
2797-2801 |
IN |
denotes |
with |
T8864 |
2802-2805 |
NN |
denotes |
LPS |
T8865 |
2806-2809 |
CC |
denotes |
and |
T8866 |
2810-2819 |
JJ |
denotes |
apoptotic |
T8867 |
2820-2825 |
NNS |
denotes |
cells |
T8868 |
2825-2827 |
, |
denotes |
, |
T8869 |
2827-2837 |
VBG |
denotes |
indicating |
T8870 |
2838-2842 |
IN |
denotes |
that |
T8872 |
2843-2848 |
NN |
denotes |
Ptdsr |
T8874 |
2848-2849 |
HYPH |
denotes |
- |
T8873 |
2849-2858 |
JJ |
denotes |
deficient |
T8875 |
2859-2870 |
NNS |
denotes |
macrophages |
T8871 |
2871-2875 |
VBP |
denotes |
have |
T8876 |
2876-2877 |
DT |
denotes |
a |
T8878 |
2878-2885 |
VBN |
denotes |
reduced |
T8877 |
2886-2894 |
NN |
denotes |
capacity |
T8879 |
2895-2897 |
TO |
denotes |
to |
T8880 |
2898-2905 |
VB |
denotes |
produce |
T8881 |
2906-2908 |
CC |
denotes |
or |
T8882 |
2909-2916 |
VB |
denotes |
secrete |
T8883 |
2917-2920 |
JJ |
denotes |
pro |
T8885 |
2920-2921 |
HYPH |
denotes |
- |
T8886 |
2922-2925 |
CC |
denotes |
and |
T8887 |
2926-2943 |
JJ |
denotes |
anti-inflammatory |
T8884 |
2944-2953 |
NNS |
denotes |
cytokines |
T8888 |
2953-2954 |
. |
denotes |
. |
R4739 |
T8339 |
T8340 |
compound |
Ptdsr,deficiency |
R4740 |
T8340 |
T8342 |
nsubj |
deficiency,results |
R4741 |
T8341 |
T8340 |
punct |
-,deficiency |
R4742 |
T8343 |
T8342 |
prep |
in,results |
R4743 |
T8344 |
T8345 |
amod |
reduced,production |
R4744 |
T8345 |
T8343 |
pobj |
production,in |
R4745 |
T8346 |
T8345 |
prep |
of,production |
R4746 |
T8347 |
T8348 |
amod |
pro,cytokines |
R4747 |
T8348 |
T8346 |
pobj |
cytokines,of |
R4748 |
T8349 |
T8347 |
punct |
-,pro |
R4749 |
T8350 |
T8347 |
cc |
and,pro |
R4750 |
T8351 |
T8347 |
conj |
anti-inflammatory,pro |
R4751 |
T8352 |
T8342 |
prep |
after,results |
R4752 |
T8353 |
T8354 |
compound |
macrophage,stimulation |
R4753 |
T8354 |
T8352 |
pobj |
stimulation,after |
R4754 |
T8356 |
T8357 |
prep |
In,proposed |
R4755 |
T8358 |
T8356 |
pobj |
addition,In |
R4756 |
T8359 |
T8358 |
prep |
to,addition |
R4757 |
T8360 |
T8361 |
poss |
its,importance |
R4758 |
T8361 |
T8359 |
pobj |
importance,to |
R4759 |
T8362 |
T8361 |
amod |
suggested,importance |
R4760 |
T8363 |
T8361 |
prep |
for,importance |
R4761 |
T8364 |
T8363 |
pobj |
phagocytosis,for |
R4762 |
T8365 |
T8364 |
prep |
of,phagocytosis |
R4763 |
T8366 |
T8367 |
amod |
apoptotic,cells |
R4764 |
T8367 |
T8365 |
pobj |
cells,of |
R4765 |
T8368 |
T8357 |
punct |
", ",proposed |
R4766 |
T8369 |
T8357 |
nsubjpass |
it,proposed |
R4767 |
T8370 |
T8357 |
aux |
has,proposed |
R4768 |
T8371 |
T8357 |
auxpass |
been,proposed |
R4769 |
T8372 |
T8373 |
mark |
that,fulfils |
R4770 |
T8373 |
T8357 |
ccomp |
fulfils,proposed |
R4771 |
T8374 |
T8373 |
nsubj |
Ptdsr,fulfils |
R4772 |
T8375 |
T8376 |
det |
a,role |
R4773 |
T8376 |
T8373 |
dobj |
role,fulfils |
R4774 |
T8377 |
T8376 |
amod |
second,role |
R4775 |
T8378 |
T8376 |
amod |
crucial,role |
R4776 |
T8379 |
T8376 |
prep |
in,role |
R4777 |
T8380 |
T8379 |
pcomp |
regulating,in |
R4778 |
T8381 |
T8380 |
cc |
and,regulating |
R4779 |
T8382 |
T8380 |
conj |
maintaining,regulating |
R4780 |
T8383 |
T8384 |
det |
a,environment |
R4781 |
T8384 |
T8382 |
dobj |
environment,maintaining |
R4782 |
T8385 |
T8384 |
amod |
non-inflammatory,environment |
R4783 |
T8386 |
T8382 |
prep |
upon,maintaining |
R4784 |
T8387 |
T8388 |
det |
the,recognition |
R4785 |
T8388 |
T8386 |
pobj |
recognition,upon |
R4786 |
T8389 |
T8388 |
prep |
of,recognition |
R4787 |
T8390 |
T8391 |
amod |
apoptotic,cells |
R4788 |
T8391 |
T8389 |
pobj |
cells,of |
R4789 |
T8392 |
T8388 |
prep |
by,recognition |
R4790 |
T8393 |
T8392 |
pobj |
macrophages,by |
R4791 |
T8394 |
T8395 |
punct |
[,26 |
R4792 |
T8395 |
T8357 |
parataxis |
26,proposed |
R4793 |
T8396 |
T8395 |
punct |
],26 |
R4794 |
T8397 |
T8357 |
punct |
.,proposed |
R4795 |
T8399 |
T8400 |
nsubj |
We,tested |
R4796 |
T8401 |
T8400 |
advmod |
therefore,tested |
R4797 |
T8402 |
T8403 |
mark |
whether,were |
R4798 |
T8403 |
T8400 |
ccomp |
were,tested |
R4799 |
T8404 |
T8405 |
nmod |
Ptdsr,macrophages |
R4800 |
T8405 |
T8403 |
nsubj |
macrophages,were |
R4801 |
T8406 |
T8404 |
punct |
-,Ptdsr |
R4802 |
T8407 |
T8404 |
punct |
/,Ptdsr |
R4803 |
T8408 |
T8404 |
punct |
-,Ptdsr |
R4804 |
T8409 |
T8403 |
acomp |
able,were |
R4805 |
T8410 |
T8411 |
aux |
to,release |
R4806 |
T8411 |
T8409 |
xcomp |
release,able |
R4807 |
T8412 |
T8413 |
amod |
anti-inflammatory,cytokines |
R4808 |
T8413 |
T8411 |
dobj |
cytokines,release |
R4809 |
T8414 |
T8411 |
prep |
after,release |
R4810 |
T8415 |
T8414 |
pobj |
ingestion,after |
R4811 |
T8416 |
T8415 |
prep |
of,ingestion |
R4812 |
T8417 |
T8418 |
amod |
apoptotic,cells |
R4813 |
T8418 |
T8416 |
pobj |
cells,of |
R4814 |
T8419 |
T8400 |
punct |
.,tested |
R4815 |
T8421 |
T8422 |
nsubj |
We,examined |
R4816 |
T8423 |
T8422 |
dobj |
levels,examined |
R4817 |
T8424 |
T8423 |
prep |
of,levels |
R4818 |
T8425 |
T8426 |
compound |
TGF,β1 |
R4819 |
T8426 |
T8424 |
pobj |
β1,of |
R4820 |
T8427 |
T8426 |
punct |
-,β1 |
R4821 |
T8428 |
T8426 |
cc |
and,β1 |
R4822 |
T8429 |
T8426 |
conj |
interleukin,β1 |
R4823 |
T8430 |
T8429 |
punct |
-,interleukin |
R4824 |
T8431 |
T8429 |
nummod |
10,interleukin |
R4825 |
T8432 |
T8433 |
punct |
(,IL |
R4826 |
T8433 |
T8429 |
parataxis |
IL,interleukin |
R4827 |
T8434 |
T8433 |
punct |
-,IL |
R4828 |
T8435 |
T8433 |
nummod |
10,IL |
R4829 |
T8436 |
T8433 |
punct |
),IL |
R4830 |
T8437 |
T8422 |
prep |
after,examined |
R4831 |
T8438 |
T8437 |
pobj |
stimulation,after |
R4832 |
T8439 |
T8438 |
prep |
of,stimulation |
R4833 |
T8440 |
T8439 |
pobj |
FLDMs,of |
R4834 |
T8441 |
T8438 |
prep |
with,stimulation |
R4835 |
T8442 |
T8441 |
pobj |
lipopolysaccharide,with |
R4836 |
T8443 |
T8442 |
punct |
(,lipopolysaccharide |
R4837 |
T8444 |
T8442 |
appos |
LPS,lipopolysaccharide |
R4838 |
T8445 |
T8422 |
punct |
),examined |
R4839 |
T8446 |
T8422 |
punct |
", ",examined |
R4840 |
T8447 |
T8422 |
prep |
with,examined |
R4841 |
T8448 |
T8447 |
cc |
and,with |
R4842 |
T8449 |
T8447 |
conj |
without,with |
R4843 |
T8450 |
T8449 |
pobj |
co-culture,without |
R4844 |
T8451 |
T8450 |
prep |
of,co-culture |
R4845 |
T8452 |
T8453 |
amod |
apoptotic,cells |
R4846 |
T8453 |
T8451 |
pobj |
cells,of |
R4847 |
T8454 |
T8422 |
punct |
.,examined |
R4848 |
T8456 |
T8457 |
nsubj |
Quantification,demonstrated |
R4849 |
T8458 |
T8456 |
prep |
of,Quantification |
R4850 |
T8459 |
T8460 |
nmod |
TGF,β1 |
R4851 |
T8460 |
T8462 |
nmod |
β1,levels |
R4852 |
T8461 |
T8460 |
punct |
-,β1 |
R4853 |
T8462 |
T8458 |
pobj |
levels,of |
R4854 |
T8463 |
T8460 |
cc |
and,β1 |
R4855 |
T8464 |
T8460 |
conj |
IL,β1 |
R4856 |
T8465 |
T8464 |
punct |
-,IL |
R4857 |
T8466 |
T8464 |
nummod |
10,IL |
R4858 |
T8467 |
T8456 |
prep |
after,Quantification |
R4859 |
T8468 |
T8469 |
nummod |
22,hours |
R4860 |
T8469 |
T8467 |
pobj |
hours,after |
R4861 |
T8470 |
T8469 |
prep |
of,hours |
R4862 |
T8471 |
T8470 |
pobj |
culture,of |
R4863 |
T8472 |
T8473 |
mark |
that,were |
R4864 |
T8473 |
T8457 |
ccomp |
were,demonstrated |
R4865 |
T8474 |
T8475 |
nmod |
Ptdsr,macrophages |
R4866 |
T8475 |
T8473 |
nsubj |
macrophages,were |
R4867 |
T8476 |
T8474 |
punct |
-,Ptdsr |
R4868 |
T8477 |
T8474 |
punct |
/,Ptdsr |
R4869 |
T8478 |
T8474 |
punct |
-,Ptdsr |
R4870 |
T8479 |
T8473 |
acomp |
able,were |
R4871 |
T8480 |
T8481 |
aux |
to,secrete |
R4872 |
T8481 |
T8479 |
xcomp |
secrete,able |
R4873 |
T8482 |
T8483 |
det |
these,cytokines |
R4874 |
T8483 |
T8481 |
dobj |
cytokines,secrete |
R4875 |
T8484 |
T8483 |
amod |
anti-inflammatory,cytokines |
R4876 |
T8485 |
T8481 |
prep |
upon,secrete |
R4877 |
T8486 |
T8485 |
pobj |
ingestion,upon |
R4878 |
T8487 |
T8486 |
prep |
of,ingestion |
R4879 |
T8488 |
T8489 |
amod |
apoptotic,cells |
R4880 |
T8489 |
T8487 |
pobj |
cells,of |
R4881 |
T8490 |
T8481 |
punct |
", ",secrete |
R4882 |
T8491 |
T8492 |
mark |
although,at |
R4883 |
T8492 |
T8481 |
advcl |
at,secrete |
R4884 |
T8493 |
T8494 |
det |
a,level |
R4885 |
T8494 |
T8492 |
pobj |
level,at |
R4886 |
T8495 |
T8496 |
advmod |
slightly,lower |
R4887 |
T8496 |
T8494 |
amod |
lower,level |
R4888 |
T8497 |
T8494 |
prep |
than,level |
R4889 |
T8498 |
T8499 |
amod |
wild,type |
R4890 |
T8499 |
T8497 |
pobj |
type,than |
R4891 |
T8500 |
T8499 |
punct |
-,type |
R4892 |
T8501 |
T8502 |
punct |
(,b |
R4893 |
T8502 |
T8457 |
parataxis |
b,demonstrated |
R4894 |
T8503 |
T8502 |
nmod |
Figure,b |
R4895 |
T8504 |
T8502 |
nmod |
8a,b |
R4896 |
T8505 |
T8502 |
punct |
",",b |
R4897 |
T8506 |
T8502 |
punct |
),b |
R4898 |
T8507 |
T8457 |
punct |
.,demonstrated |
R4899 |
T8509 |
T8510 |
nsubj |
This,indicates |
R4900 |
T8511 |
T8512 |
mark |
that,compromise |
R4901 |
T8512 |
T8510 |
ccomp |
compromise,indicates |
R4902 |
T8513 |
T8512 |
nsubj |
ablation,compromise |
R4903 |
T8514 |
T8513 |
prep |
of,ablation |
R4904 |
T8515 |
T8516 |
compound |
Ptdsr,function |
R4905 |
T8516 |
T8514 |
pobj |
function,of |
R4906 |
T8517 |
T8512 |
aux |
does,compromise |
R4907 |
T8518 |
T8512 |
neg |
not,compromise |
R4908 |
T8519 |
T8512 |
prep |
in,compromise |
R4909 |
T8520 |
T8519 |
amod |
general,in |
R4910 |
T8521 |
T8522 |
det |
the,ability |
R4911 |
T8522 |
T8512 |
dobj |
ability,compromise |
R4912 |
T8523 |
T8522 |
prep |
of,ability |
R4913 |
T8524 |
T8523 |
pobj |
macrophages,of |
R4914 |
T8525 |
T8526 |
aux |
to,release |
R4915 |
T8526 |
T8522 |
acl |
release,ability |
R4916 |
T8527 |
T8528 |
npadvmod |
immune,suppressive |
R4917 |
T8528 |
T8530 |
amod |
suppressive,cytokines |
R4918 |
T8529 |
T8528 |
punct |
-,suppressive |
R4919 |
T8530 |
T8526 |
dobj |
cytokines,release |
R4920 |
T8531 |
T8526 |
prep |
after,release |
R4921 |
T8532 |
T8531 |
pobj |
recognition,after |
R4922 |
T8533 |
T8532 |
cc |
and,recognition |
R4923 |
T8534 |
T8532 |
conj |
engulfment,recognition |
R4924 |
T8535 |
T8532 |
prep |
of,recognition |
R4925 |
T8536 |
T8537 |
amod |
apoptotic,cells |
R4926 |
T8537 |
T8535 |
pobj |
cells,of |
R4927 |
T8538 |
T8510 |
punct |
.,indicates |
R4928 |
T8540 |
T8541 |
aux |
To,analyze |
R4929 |
T8541 |
T8542 |
advcl |
analyze,stimulated |
R4930 |
T8543 |
T8544 |
mark |
whether,affected |
R4931 |
T8544 |
T8541 |
ccomp |
affected,analyze |
R4932 |
T8545 |
T8546 |
amod |
pro-inflammatory,signaling |
R4933 |
T8546 |
T8544 |
nsubjpass |
signaling,affected |
R4934 |
T8547 |
T8544 |
auxpass |
is,affected |
R4935 |
T8548 |
T8544 |
prep |
in,affected |
R4936 |
T8549 |
T8550 |
nmod |
Ptdsr,macrophages |
R4937 |
T8550 |
T8548 |
pobj |
macrophages,in |
R4938 |
T8551 |
T8549 |
punct |
-,Ptdsr |
R4939 |
T8552 |
T8549 |
punct |
/,Ptdsr |
R4940 |
T8553 |
T8549 |
punct |
-,Ptdsr |
R4941 |
T8554 |
T8542 |
punct |
", ",stimulated |
R4942 |
T8555 |
T8542 |
nsubj |
we,stimulated |
R4943 |
T8556 |
T8542 |
dobj |
FLDMs,stimulated |
R4944 |
T8557 |
T8556 |
prep |
from,FLDMs |
R4945 |
T8558 |
T8559 |
nmod |
Ptdsr,mice |
R4946 |
T8559 |
T8557 |
pobj |
mice,from |
R4947 |
T8560 |
T8558 |
punct |
+,Ptdsr |
R4948 |
T8561 |
T8558 |
punct |
/,Ptdsr |
R4949 |
T8562 |
T8558 |
punct |
+,Ptdsr |
R4950 |
T8563 |
T8558 |
cc |
and,Ptdsr |
R4951 |
T8564 |
T8558 |
conj |
Ptdsr,Ptdsr |
R4952 |
T8565 |
T8564 |
punct |
-,Ptdsr |
R4953 |
T8566 |
T8564 |
punct |
/,Ptdsr |
R4954 |
T8567 |
T8564 |
punct |
-,Ptdsr |
R4955 |
T8568 |
T8542 |
prep |
with,stimulated |
R4956 |
T8569 |
T8568 |
pobj |
LPS,with |
R4957 |
T8570 |
T8542 |
cc |
and,stimulated |
R4958 |
T8571 |
T8542 |
conj |
measured,stimulated |
R4959 |
T8572 |
T8571 |
dobj |
levels,measured |
R4960 |
T8573 |
T8572 |
prep |
of,levels |
R4961 |
T8574 |
T8575 |
compound |
tumor,α |
R4962 |
T8575 |
T8573 |
pobj |
α,of |
R4963 |
T8576 |
T8575 |
compound |
necrosis,α |
R4964 |
T8577 |
T8575 |
compound |
factor,α |
R4965 |
T8578 |
T8575 |
punct |
-,α |
R4966 |
T8579 |
T8580 |
punct |
(,α |
R4967 |
T8580 |
T8575 |
appos |
α,α |
R4968 |
T8581 |
T8580 |
compound |
TNF,α |
R4969 |
T8582 |
T8580 |
punct |
-,α |
R4970 |
T8583 |
T8571 |
punct |
),measured |
R4971 |
T8584 |
T8571 |
prep |
at,measured |
R4972 |
T8585 |
T8586 |
amod |
different,points |
R4973 |
T8586 |
T8584 |
pobj |
points,at |
R4974 |
T8587 |
T8586 |
compound |
time,points |
R4975 |
T8588 |
T8586 |
prep |
after,points |
R4976 |
T8589 |
T8588 |
pobj |
stimulation,after |
R4977 |
T8590 |
T8591 |
punct |
(,8c |
R4978 |
T8591 |
T8571 |
parataxis |
8c,measured |
R4979 |
T8592 |
T8591 |
compound |
Figure,8c |
R4980 |
T8593 |
T8591 |
punct |
),8c |
R4981 |
T8594 |
T8542 |
punct |
.,stimulated |
R4982 |
T8596 |
T8597 |
nmod |
Ptdsr,macrophages |
R4983 |
T8597 |
T8601 |
nsubj |
macrophages,produced |
R4984 |
T8598 |
T8596 |
punct |
-,Ptdsr |
R4985 |
T8599 |
T8596 |
punct |
/,Ptdsr |
R4986 |
T8600 |
T8596 |
punct |
-,Ptdsr |
R4987 |
T8602 |
T8603 |
advmod |
significantly,less |
R4988 |
T8603 |
T8604 |
amod |
less,α |
R4989 |
T8604 |
T8601 |
dobj |
α,produced |
R4990 |
T8605 |
T8604 |
compound |
TNF,α |
R4991 |
T8606 |
T8604 |
punct |
-,α |
R4992 |
T8607 |
T8608 |
mark |
than,did |
R4993 |
T8608 |
T8604 |
advcl |
did,α |
R4994 |
T8609 |
T8610 |
amod |
wild,type |
R4995 |
T8610 |
T8612 |
compound |
type,macrophages |
R4996 |
T8611 |
T8610 |
punct |
-,type |
R4997 |
T8612 |
T8608 |
nsubj |
macrophages,did |
R4998 |
T8613 |
T8601 |
punct |
.,produced |
R4999 |
T8615 |
T8616 |
det |
The,difference |
R5000 |
T8616 |
T8617 |
nsubj |
difference,was |
R5001 |
T8618 |
T8616 |
prep |
in,difference |
R5002 |
T8619 |
T8620 |
compound |
TNF,α |
R5003 |
T8620 |
T8622 |
compound |
α,secretion |
R5004 |
T8621 |
T8620 |
punct |
-,α |
R5005 |
T8622 |
T8618 |
pobj |
secretion,in |
R5006 |
T8623 |
T8617 |
advmod |
first,was |
R5007 |
T8624 |
T8617 |
acomp |
visible,was |
R5008 |
T8625 |
T8617 |
prep |
after,was |
R5009 |
T8626 |
T8627 |
nummod |
3,h |
R5010 |
T8627 |
T8625 |
pobj |
h,after |
R5011 |
T8628 |
T8627 |
prep |
of,h |
R5012 |
T8629 |
T8630 |
compound |
LPS,stimulation |
R5013 |
T8630 |
T8628 |
pobj |
stimulation,of |
R5014 |
T8631 |
T8617 |
cc |
and,was |
R5015 |
T8632 |
T8617 |
conj |
became,was |
R5016 |
T8633 |
T8634 |
advmod |
more,prominent |
R5017 |
T8634 |
T8632 |
acomp |
prominent,became |
R5018 |
T8635 |
T8632 |
prep |
during,became |
R5019 |
T8636 |
T8637 |
det |
the,course |
R5020 |
T8637 |
T8635 |
pobj |
course,during |
R5021 |
T8638 |
T8637 |
prep |
of,course |
R5022 |
T8639 |
T8640 |
det |
the,experiment |
R5023 |
T8640 |
T8638 |
pobj |
experiment,of |
R5024 |
T8641 |
T8642 |
punct |
(,8c |
R5025 |
T8642 |
T8632 |
parataxis |
8c,became |
R5026 |
T8643 |
T8642 |
prep |
for,8c |
R5027 |
T8644 |
T8643 |
pobj |
example,for |
R5028 |
T8645 |
T8642 |
punct |
", ",8c |
R5029 |
T8646 |
T8642 |
prep |
after,8c |
R5030 |
T8647 |
T8648 |
nummod |
9,h |
R5031 |
T8648 |
T8646 |
pobj |
h,after |
R5032 |
T8649 |
T8648 |
cc |
and,h |
R5033 |
T8650 |
T8651 |
nummod |
12,h |
R5034 |
T8651 |
T8648 |
conj |
h,h |
R5035 |
T8652 |
T8648 |
prep |
of,h |
R5036 |
T8653 |
T8654 |
compound |
LPS,stimulation |
R5037 |
T8654 |
T8652 |
pobj |
stimulation,of |
R5038 |
T8655 |
T8642 |
punct |
;,8c |
R5039 |
T8656 |
T8642 |
compound |
Figure,8c |
R5040 |
T8657 |
T8642 |
punct |
),8c |
R5041 |
T8658 |
T8617 |
punct |
.,was |
R5042 |
T8660 |
T8661 |
aux |
To,analyze |
R5043 |
T8661 |
T8662 |
advcl |
analyze,stimulated |
R5044 |
T8663 |
T8664 |
mark |
whether,affected |
R5045 |
T8664 |
T8661 |
ccomp |
affected,analyze |
R5046 |
T8665 |
T8666 |
compound |
TNF,α |
R5047 |
T8666 |
T8668 |
compound |
α,release |
R5048 |
T8667 |
T8666 |
punct |
-,α |
R5049 |
T8668 |
T8664 |
nsubjpass |
release,affected |
R5050 |
T8669 |
T8668 |
prep |
by,release |
R5051 |
T8670 |
T8671 |
nmod |
Ptdsr,macrophages |
R5052 |
T8671 |
T8669 |
pobj |
macrophages,by |
R5053 |
T8672 |
T8670 |
punct |
-,Ptdsr |
R5054 |
T8673 |
T8670 |
punct |
/,Ptdsr |
R5055 |
T8674 |
T8670 |
punct |
-,Ptdsr |
R5056 |
T8675 |
T8664 |
aux |
can,affected |
R5057 |
T8676 |
T8664 |
auxpass |
be,affected |
R5058 |
T8677 |
T8664 |
prep |
by,affected |
R5059 |
T8678 |
T8677 |
pobj |
engulfment,by |
R5060 |
T8679 |
T8678 |
prep |
of,engulfment |
R5061 |
T8680 |
T8681 |
amod |
apoptotic,cells |
R5062 |
T8681 |
T8679 |
pobj |
cells,of |
R5063 |
T8682 |
T8662 |
punct |
", ",stimulated |
R5064 |
T8683 |
T8662 |
nsubj |
we,stimulated |
R5065 |
T8684 |
T8662 |
dobj |
FLDMs,stimulated |
R5066 |
T8685 |
T8662 |
prep |
with,stimulated |
R5067 |
T8686 |
T8685 |
pobj |
LPS,with |
R5068 |
T8687 |
T8686 |
punct |
", ",LPS |
R5069 |
T8688 |
T8689 |
amod |
apoptotic,cells |
R5070 |
T8689 |
T8686 |
conj |
cells,LPS |
R5071 |
T8690 |
T8689 |
cc |
or,cells |
R5072 |
T8691 |
T8689 |
conj |
both,cells |
R5073 |
T8692 |
T8662 |
punct |
.,stimulated |
R5074 |
T8694 |
T8695 |
nsubj |
Quantification,showed |
R5075 |
T8696 |
T8694 |
prep |
of,Quantification |
R5076 |
T8697 |
T8698 |
compound |
TNF,α |
R5077 |
T8698 |
T8700 |
compound |
α,levels |
R5078 |
T8699 |
T8698 |
punct |
-,α |
R5079 |
T8700 |
T8696 |
pobj |
levels,of |
R5080 |
T8701 |
T8694 |
prep |
by,Quantification |
R5081 |
T8702 |
T8701 |
pobj |
ELISA,by |
R5082 |
T8703 |
T8694 |
prep |
after,Quantification |
R5083 |
T8704 |
T8705 |
nummod |
22,h |
R5084 |
T8705 |
T8703 |
pobj |
h,after |
R5085 |
T8706 |
T8707 |
mark |
that,release |
R5086 |
T8707 |
T8695 |
ccomp |
release,showed |
R5087 |
T8708 |
T8709 |
npadvmod |
Ptdsr,deficient |
R5088 |
T8709 |
T8711 |
amod |
deficient,macrophages |
R5089 |
T8710 |
T8709 |
punct |
-,deficient |
R5090 |
T8711 |
T8707 |
nsubj |
macrophages,release |
R5091 |
T8712 |
T8713 |
amod |
less,α |
R5092 |
T8713 |
T8707 |
dobj |
α,release |
R5093 |
T8714 |
T8713 |
compound |
TNF,α |
R5094 |
T8715 |
T8713 |
punct |
-,α |
R5095 |
T8716 |
T8707 |
prep |
after,release |
R5096 |
T8717 |
T8716 |
pobj |
stimulation,after |
R5097 |
T8718 |
T8717 |
prep |
with,stimulation |
R5098 |
T8719 |
T8718 |
pobj |
LPS,with |
R5099 |
T8720 |
T8719 |
advmod |
alone,LPS |
R5100 |
T8721 |
T8716 |
punct |
", ",after |
R5101 |
T8722 |
T8716 |
cc |
and,after |
R5102 |
T8723 |
T8722 |
advmod |
also,and |
R5103 |
T8724 |
T8716 |
conj |
after,after |
R5104 |
T8725 |
T8726 |
amod |
double,stimulation |
R5105 |
T8726 |
T8724 |
pobj |
stimulation,after |
R5106 |
T8727 |
T8726 |
prep |
of,stimulation |
R5107 |
T8728 |
T8727 |
pobj |
macrophages,of |
R5108 |
T8729 |
T8726 |
prep |
with,stimulation |
R5109 |
T8730 |
T8729 |
pobj |
LPS,with |
R5110 |
T8731 |
T8730 |
cc |
and,LPS |
R5111 |
T8732 |
T8733 |
amod |
apoptotic,cells |
R5112 |
T8733 |
T8730 |
conj |
cells,LPS |
R5113 |
T8734 |
T8735 |
punct |
(,8d |
R5114 |
T8735 |
T8695 |
parataxis |
8d,showed |
R5115 |
T8736 |
T8735 |
compound |
Figure,8d |
R5116 |
T8737 |
T8735 |
punct |
),8d |
R5117 |
T8738 |
T8695 |
punct |
.,showed |
R5118 |
T8740 |
T8741 |
advmod |
Moreover,demonstrated |
R5119 |
T8742 |
T8741 |
punct |
", ",demonstrated |
R5120 |
T8743 |
T8744 |
det |
the,stimulation |
R5121 |
T8744 |
T8741 |
nsubj |
stimulation,demonstrated |
R5122 |
T8745 |
T8744 |
amod |
double,stimulation |
R5123 |
T8746 |
T8747 |
mark |
that,inhibited |
R5124 |
T8747 |
T8741 |
ccomp |
inhibited,demonstrated |
R5125 |
T8748 |
T8749 |
det |
the,release |
R5126 |
T8749 |
T8747 |
nsubjpass |
release,inhibited |
R5127 |
T8750 |
T8751 |
npadvmod |
LPS,induced |
R5128 |
T8751 |
T8749 |
amod |
induced,release |
R5129 |
T8752 |
T8751 |
punct |
-,induced |
R5130 |
T8753 |
T8754 |
compound |
TNF,α |
R5131 |
T8754 |
T8749 |
compound |
α,release |
R5132 |
T8755 |
T8754 |
punct |
-,α |
R5133 |
T8756 |
T8749 |
prep |
by,release |
R5134 |
T8757 |
T8758 |
nmod |
Ptdsr,macrophages |
R5135 |
T8758 |
T8756 |
pobj |
macrophages,by |
R5136 |
T8759 |
T8757 |
punct |
-,Ptdsr |
R5137 |
T8760 |
T8757 |
punct |
/,Ptdsr |
R5138 |
T8761 |
T8757 |
punct |
-,Ptdsr |
R5139 |
T8762 |
T8747 |
aux |
could,inhibited |
R5140 |
T8763 |
T8747 |
auxpass |
be,inhibited |
R5141 |
T8764 |
T8747 |
prep |
by,inhibited |
R5142 |
T8765 |
T8764 |
pobj |
co-administration,by |
R5143 |
T8766 |
T8765 |
prep |
of,co-administration |
R5144 |
T8767 |
T8768 |
amod |
apoptotic,cells |
R5145 |
T8768 |
T8766 |
pobj |
cells,of |
R5146 |
T8769 |
T8747 |
prep |
to,inhibited |
R5147 |
T8770 |
T8771 |
det |
an,extent |
R5148 |
T8771 |
T8769 |
pobj |
extent,to |
R5149 |
T8772 |
T8771 |
amod |
comparable,extent |
R5150 |
T8773 |
T8772 |
prep |
to,comparable |
R5151 |
T8774 |
T8773 |
pobj |
that,to |
R5152 |
T8775 |
T8774 |
acl |
seen,that |
R5153 |
T8776 |
T8775 |
prep |
in,seen |
R5154 |
T8777 |
T8778 |
amod |
wild,type |
R5155 |
T8778 |
T8780 |
compound |
type,macrophages |
R5156 |
T8779 |
T8778 |
punct |
-,type |
R5157 |
T8780 |
T8776 |
pobj |
macrophages,in |
R5158 |
T8781 |
T8741 |
punct |
.,demonstrated |
R5159 |
T8783 |
T8784 |
amod |
Similar,results |
R5160 |
T8784 |
T8785 |
nsubjpass |
results,obtained |
R5161 |
T8786 |
T8785 |
auxpass |
were,obtained |
R5162 |
T8787 |
T8788 |
advmod |
when,analyzed |
R5163 |
T8788 |
T8785 |
advcl |
analyzed,obtained |
R5164 |
T8789 |
T8790 |
amod |
other,cytokines |
R5165 |
T8790 |
T8788 |
nsubjpass |
cytokines,analyzed |
R5166 |
T8791 |
T8790 |
amod |
pro-inflammatory,cytokines |
R5167 |
T8792 |
T8790 |
punct |
", ",cytokines |
R5168 |
T8793 |
T8794 |
amod |
such,as |
R5169 |
T8794 |
T8790 |
prep |
as,cytokines |
R5170 |
T8795 |
T8794 |
pobj |
interleukin,as |
R5171 |
T8796 |
T8795 |
punct |
-,interleukin |
R5172 |
T8797 |
T8795 |
nummod |
6,interleukin |
R5173 |
T8798 |
T8795 |
cc |
and,interleukin |
R5174 |
T8799 |
T8800 |
compound |
monocyte,protein |
R5175 |
T8800 |
T8795 |
conj |
protein,interleukin |
R5176 |
T8801 |
T8800 |
compound |
chemoattractant,protein |
R5177 |
T8802 |
T8800 |
punct |
-,protein |
R5178 |
T8803 |
T8800 |
nummod |
1,protein |
R5179 |
T8804 |
T8788 |
punct |
", ",analyzed |
R5180 |
T8805 |
T8788 |
auxpass |
were,analyzed |
R5181 |
T8806 |
T8807 |
punct |
(,shown |
R5182 |
T8807 |
T8785 |
parataxis |
shown,obtained |
R5183 |
T8808 |
T8807 |
nsubj |
data,shown |
R5184 |
T8809 |
T8807 |
neg |
not,shown |
R5185 |
T8810 |
T8807 |
punct |
),shown |
R5186 |
T8811 |
T8785 |
punct |
.,obtained |
R5187 |
T8813 |
T8814 |
det |
These,results |
R5188 |
T8814 |
T8815 |
nsubj |
results,indicate |
R5189 |
T8816 |
T8817 |
mark |
that,required |
R5190 |
T8817 |
T8815 |
ccomp |
required,indicate |
R5191 |
T8818 |
T8817 |
nsubjpass |
Ptdsr,required |
R5192 |
T8819 |
T8817 |
auxpass |
is,required |
R5193 |
T8820 |
T8817 |
neg |
not,required |
R5194 |
T8821 |
T8817 |
prep |
in,required |
R5195 |
T8822 |
T8821 |
pobj |
macrophages,in |
R5196 |
T8823 |
T8817 |
prep |
for,required |
R5197 |
T8824 |
T8825 |
det |
the,inhibition |
R5198 |
T8825 |
T8823 |
pobj |
inhibition,for |
R5199 |
T8826 |
T8825 |
prep |
of,inhibition |
R5200 |
T8827 |
T8828 |
amod |
pro-inflammatory,signaling |
R5201 |
T8828 |
T8826 |
pobj |
signaling,of |
R5202 |
T8829 |
T8817 |
prep |
after,required |
R5203 |
T8830 |
T8829 |
pobj |
recognition,after |
R5204 |
T8831 |
T8830 |
cc |
and,recognition |
R5205 |
T8832 |
T8830 |
conj |
engulfment,recognition |
R5206 |
T8833 |
T8830 |
prep |
of,recognition |
R5207 |
T8834 |
T8835 |
amod |
apoptotic,cells |
R5208 |
T8835 |
T8833 |
pobj |
cells,of |
R5209 |
T8836 |
T8815 |
punct |
.,indicate |
R5210 |
T8838 |
T8839 |
compound |
Ptdsr,deficiency |
R5211 |
T8839 |
T8841 |
nsubj |
deficiency,affect |
R5212 |
T8840 |
T8839 |
punct |
-,deficiency |
R5213 |
T8842 |
T8841 |
aux |
does,affect |
R5214 |
T8843 |
T8841 |
punct |
", ",affect |
R5215 |
T8844 |
T8841 |
advmod |
however,affect |
R5216 |
T8845 |
T8841 |
punct |
", ",affect |
R5217 |
T8846 |
T8847 |
det |
the,release |
R5218 |
T8847 |
T8841 |
dobj |
release,affect |
R5219 |
T8848 |
T8847 |
amod |
overall,release |
R5220 |
T8849 |
T8847 |
prep |
of,release |
R5221 |
T8850 |
T8851 |
amod |
pro,cytokines |
R5222 |
T8851 |
T8849 |
pobj |
cytokines,of |
R5223 |
T8852 |
T8850 |
punct |
-,pro |
R5224 |
T8853 |
T8850 |
cc |
and,pro |
R5225 |
T8854 |
T8850 |
conj |
anti-inflammatory,pro |
R5226 |
T8855 |
T8841 |
prep |
after,affect |
R5227 |
T8856 |
T8855 |
pobj |
stimulation,after |
R5228 |
T8857 |
T8856 |
prep |
with,stimulation |
R5229 |
T8858 |
T8857 |
pobj |
LPS,with |
R5230 |
T8859 |
T8855 |
cc |
and,after |
R5231 |
T8860 |
T8855 |
conj |
after,after |
R5232 |
T8861 |
T8862 |
amod |
double,treatment |
R5233 |
T8862 |
T8860 |
pobj |
treatment,after |
R5234 |
T8863 |
T8862 |
prep |
with,treatment |
R5235 |
T8864 |
T8863 |
pobj |
LPS,with |
R5236 |
T8865 |
T8864 |
cc |
and,LPS |
R5237 |
T8866 |
T8867 |
amod |
apoptotic,cells |
R5238 |
T8867 |
T8864 |
conj |
cells,LPS |
R5239 |
T8868 |
T8841 |
punct |
", ",affect |
R5240 |
T8869 |
T8841 |
advcl |
indicating,affect |
R5241 |
T8870 |
T8871 |
mark |
that,have |
R5242 |
T8871 |
T8869 |
ccomp |
have,indicating |
R5243 |
T8872 |
T8873 |
npadvmod |
Ptdsr,deficient |
R5244 |
T8873 |
T8875 |
amod |
deficient,macrophages |
R5245 |
T8874 |
T8873 |
punct |
-,deficient |
R5246 |
T8875 |
T8871 |
nsubj |
macrophages,have |
R5247 |
T8876 |
T8877 |
det |
a,capacity |
R5248 |
T8877 |
T8871 |
dobj |
capacity,have |
R5249 |
T8878 |
T8877 |
amod |
reduced,capacity |
R5250 |
T8879 |
T8880 |
aux |
to,produce |
R5251 |
T8880 |
T8877 |
acl |
produce,capacity |
R5252 |
T8881 |
T8880 |
cc |
or,produce |
R5253 |
T8882 |
T8880 |
conj |
secrete,produce |
R5254 |
T8883 |
T8884 |
amod |
pro,cytokines |
R5255 |
T8884 |
T8882 |
dobj |
cytokines,secrete |
R5256 |
T8885 |
T8883 |
punct |
-,pro |
R5257 |
T8886 |
T8883 |
cc |
and,pro |
R5258 |
T8887 |
T8883 |
conj |
anti-inflammatory,pro |
R5259 |
T8888 |
T8841 |
punct |
.,affect |