PMC:548520 / 28071-29105 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T6761 0-8 JJ denotes Abnormal
T6763 9-22 NN denotes photoreceptor
T6764 23-31 NN denotes terminal
T6762 32-41 NN denotes formation
T6766 42-45 VBD denotes was
T6765 46-51 VBN denotes noted
T6767 52-54 IN denotes in
T6768 55-56 DT denotes a
T6769 57-62 NN denotes study
T6770 63-67 WDT denotes that
T6771 68-76 VBD denotes examined
T6772 77-84 JJ denotes retinal
T6773 85-96 NN denotes development
T6774 97-99 IN denotes in
T6775 100-103 DT denotes the
T6777 104-111 NN denotes laminin
T6779 112-117 NN denotes beta2
T6778 118-123 NN denotes chain
T6781 123-124 HYPH denotes -
T6780 124-133 JJ denotes deficient
T6776 134-139 NN denotes mouse
T6782 140-141 -LRB- denotes [
T6783 141-143 CD denotes 52
T6784 143-144 -RRB- denotes ]
T6785 144-145 . denotes .
T6786 145-191 sentence denotes Several pathologies were noted in these mice.
T6787 146-153 JJ denotes Several
T6788 154-165 NNS denotes pathologies
T6790 166-170 VBD denotes were
T6789 171-176 VBN denotes noted
T6791 177-179 IN denotes in
T6792 180-185 DT denotes these
T6793 186-190 NNS denotes mice
T6794 190-191 . denotes .
T6795 191-384 sentence denotes First, laminin beta2 chain-deficient mice displayed abnormal outer segment elongation, but a more mild phenotype than that of the Crx-/- mice; the outer segments were reduced by 50% in length.
T6796 192-197 RB denotes First
T6798 197-199 , denotes ,
T6799 199-206 NN denotes laminin
T6801 207-212 NN denotes beta2
T6800 213-218 NN denotes chain
T6803 218-219 HYPH denotes -
T6802 219-228 JJ denotes deficient
T6804 229-233 NNS denotes mice
T6797 234-243 VBD denotes displayed
T6806 244-252 JJ denotes abnormal
T6808 253-258 JJ denotes outer
T6809 259-266 NN denotes segment
T6807 267-277 NN denotes elongation
T6810 277-279 , denotes ,
T6811 279-282 CC denotes but
T6812 283-284 DT denotes a
T6814 285-289 RBR denotes more
T6815 290-294 JJ denotes mild
T6813 295-304 NN denotes phenotype
T6816 305-309 IN denotes than
T6817 310-314 DT denotes that
T6818 315-317 IN denotes of
T6819 318-321 DT denotes the
T6821 322-325 NN denotes Crx
T6822 325-326 SYM denotes -
T6823 326-327 HYPH denotes /
T6824 327-328 SYM denotes -
T6820 329-333 NNS denotes mice
T6825 333-334 : denotes ;
T6826 335-338 DT denotes the
T6828 339-344 JJ denotes outer
T6827 345-353 NNS denotes segments
T6829 354-358 VBD denotes were
T6805 359-366 VBN denotes reduced
T6830 367-369 IN denotes by
T6831 370-372 CD denotes 50
T6832 372-373 NN denotes %
T6833 374-376 IN denotes in
T6834 377-383 NN denotes length
T6835 383-384 . denotes .
T6836 384-520 sentence denotes Also photoreceptor terminals were perturbed in laminin beta2 mutants, but again the phenotype was more subtle then that of Crx-/- mice.
T6837 385-389 RB denotes Also
T6839 390-403 NN denotes photoreceptor
T6840 404-413 NNS denotes terminals
T6841 414-418 VBD denotes were
T6838 419-428 VBN denotes perturbed
T6842 429-431 IN denotes in
T6843 432-439 NN denotes laminin
T6844 440-445 NN denotes beta2
T6845 446-453 NNS denotes mutants
T6846 453-455 , denotes ,
T6847 455-458 CC denotes but
T6848 459-464 RB denotes again
T6850 465-468 DT denotes the
T6851 469-478 NN denotes phenotype
T6849 479-482 VBD denotes was
T6852 483-487 RBR denotes more
T6853 488-494 JJ denotes subtle
T6854 495-499 IN denotes then
T6855 500-504 DT denotes that
T6856 505-507 IN denotes of
T6857 508-511 NN denotes Crx
T6859 511-512 SYM denotes -
T6860 512-513 HYPH denotes /
T6861 513-514 SYM denotes -
T6858 515-519 NNS denotes mice
T6862 519-520 . denotes .
T6863 520-724 sentence denotes The outer plexiform layer of the beta2-deficient retinas demonstrated only 7% normal invaginating synapses, while the remainder had various pathologies, including floating synaptic ribbons, as seen here.
T6864 521-524 DT denotes The
T6866 525-530 JJ denotes outer
T6867 531-540 NN denotes plexiform
T6865 541-546 NN denotes layer
T6869 547-549 IN denotes of
T6870 550-553 DT denotes the
T6872 554-559 NN denotes beta2
T6874 559-560 HYPH denotes -
T6873 560-569 JJ denotes deficient
T6871 570-577 NNS denotes retinas
T6868 578-590 VBD denotes demonstrated
T6875 591-595 RB denotes only
T6876 596-597 CD denotes 7
T6877 597-598 NN denotes %
T6879 599-605 JJ denotes normal
T6880 606-618 VBG denotes invaginating
T6878 619-627 NNS denotes synapses
T6881 627-629 , denotes ,
T6882 629-634 IN denotes while
T6884 635-638 DT denotes the
T6885 639-648 NN denotes remainder
T6883 649-652 VBD denotes had
T6886 653-660 JJ denotes various
T6887 661-672 NNS denotes pathologies
T6888 672-674 , denotes ,
T6889 674-683 VBG denotes including
T6890 684-692 VBG denotes floating
T6892 693-701 JJ denotes synaptic
T6891 702-709 NNS denotes ribbons
T6893 709-711 , denotes ,
T6894 711-713 IN denotes as
T6895 714-718 VBN denotes seen
T6896 719-723 RB denotes here
T6897 723-724 . denotes .
T6898 724-836 sentence denotes The mechanistic relationship of these two molecules, if any, in photoreceptor morphogenesis is unknown to date.
T6899 725-728 DT denotes The
T6901 729-740 JJ denotes mechanistic
T6900 741-753 NN denotes relationship
T6903 754-756 IN denotes of
T6904 757-762 DT denotes these
T6906 763-766 CD denotes two
T6905 767-776 NNS denotes molecules
T6907 776-778 , denotes ,
T6909 778-780 IN denotes if
T6908 781-784 DT denotes any
T6910 784-786 , denotes ,
T6911 786-788 IN denotes in
T6912 789-802 NN denotes photoreceptor
T6913 803-816 NN denotes morphogenesis
T6902 817-819 VBZ denotes is
T6914 820-827 JJ denotes unknown
T6915 828-830 IN denotes to
T6916 831-835 NN denotes date
T6917 835-836 . denotes .
T6918 836-1034 sentence denotes The mRNA for laminin beta2 was not detected in the SAGE study of the relative RNA levels in Crx-/- and Crx+/+ and thus we cannot comment on whether the levels of RNA for laminin beta2 were altered.
T6919 837-840 DT denotes The
T6920 841-845 NN denotes mRNA
T6922 846-849 IN denotes for
T6923 850-857 NN denotes laminin
T6924 858-863 NN denotes beta2
T6925 864-867 VBD denotes was
T6926 868-871 RB denotes not
T6921 872-880 VBN denotes detected
T6927 881-883 IN denotes in
T6928 884-887 DT denotes the
T6930 888-892 NN denotes SAGE
T6929 893-898 NN denotes study
T6931 899-901 IN denotes of
T6932 902-905 DT denotes the
T6934 906-914 JJ denotes relative
T6935 915-918 NN denotes RNA
T6933 919-925 NNS denotes levels
T6936 926-928 IN denotes in
T6937 929-932 NN denotes Crx
T6938 932-933 SYM denotes -
T6939 933-934 HYPH denotes /
T6940 934-935 SYM denotes -
T6941 936-939 CC denotes and
T6942 940-943 NN denotes Crx
T6943 943-944 SYM denotes +
T6944 944-945 HYPH denotes /
T6945 945-946 SYM denotes +
T6946 947-950 CC denotes and
T6947 951-955 RB denotes thus
T6949 956-958 PRP denotes we
T6950 959-962 MD denotes can
T6951 962-965 RB denotes not
T6948 966-973 VB denotes comment
T6952 974-976 IN denotes on
T6953 977-984 IN denotes whether
T6955 985-988 DT denotes the
T6956 989-995 NNS denotes levels
T6957 996-998 IN denotes of
T6958 999-1002 NN denotes RNA
T6959 1003-1006 IN denotes for
T6960 1007-1014 NN denotes laminin
T6961 1015-1020 NN denotes beta2
T6962 1021-1025 VBD denotes were
T6954 1026-1033 VBN denotes altered
T6963 1033-1034 . denotes .
R4054 T6761 T6762 amod Abnormal,formation
R4055 T6762 T6765 nsubjpass formation,noted
R4056 T6763 T6764 compound photoreceptor,terminal
R4057 T6764 T6762 compound terminal,formation
R4058 T6766 T6765 auxpass was,noted
R4059 T6767 T6765 prep in,noted
R4060 T6768 T6769 det a,study
R4061 T6769 T6767 pobj study,in
R4062 T6770 T6771 dep that,examined
R4063 T6771 T6769 relcl examined,study
R4064 T6772 T6773 amod retinal,development
R4065 T6773 T6771 dobj development,examined
R4066 T6774 T6771 prep in,examined
R4067 T6775 T6776 det the,mouse
R4068 T6776 T6774 pobj mouse,in
R4069 T6777 T6778 compound laminin,chain
R4070 T6778 T6780 npadvmod chain,deficient
R4071 T6779 T6778 compound beta2,chain
R4072 T6780 T6776 amod deficient,mouse
R4073 T6781 T6780 punct -,deficient
R4074 T6782 T6783 punct [,52
R4075 T6783 T6765 parataxis 52,noted
R4076 T6784 T6783 punct ],52
R4077 T6785 T6765 punct .,noted
R4078 T6787 T6788 amod Several,pathologies
R4079 T6788 T6789 nsubjpass pathologies,noted
R4080 T6790 T6789 auxpass were,noted
R4081 T6791 T6789 prep in,noted
R4082 T6792 T6793 det these,mice
R4083 T6793 T6791 pobj mice,in
R4084 T6794 T6789 punct .,noted
R4085 T6796 T6797 advmod First,displayed
R4086 T6797 T6805 ccomp displayed,reduced
R4087 T6798 T6797 punct ", ",displayed
R4088 T6799 T6800 compound laminin,chain
R4089 T6800 T6802 npadvmod chain,deficient
R4090 T6801 T6800 compound beta2,chain
R4091 T6802 T6804 amod deficient,mice
R4092 T6803 T6802 punct -,deficient
R4093 T6804 T6797 nsubj mice,displayed
R4094 T6806 T6807 amod abnormal,elongation
R4095 T6807 T6797 dobj elongation,displayed
R4096 T6808 T6809 amod outer,segment
R4097 T6809 T6807 compound segment,elongation
R4098 T6810 T6807 punct ", ",elongation
R4099 T6811 T6807 cc but,elongation
R4100 T6812 T6813 det a,phenotype
R4101 T6813 T6807 conj phenotype,elongation
R4102 T6814 T6815 advmod more,mild
R4103 T6815 T6813 nmod mild,phenotype
R4104 T6816 T6813 prep than,phenotype
R4105 T6817 T6816 pobj that,than
R4106 T6818 T6817 prep of,that
R4107 T6819 T6820 det the,mice
R4108 T6820 T6818 pobj mice,of
R4109 T6821 T6820 nmod Crx,mice
R4110 T6822 T6821 punct -,Crx
R4111 T6823 T6821 punct /,Crx
R4112 T6824 T6821 punct -,Crx
R4113 T6825 T6805 punct ;,reduced
R4114 T6826 T6827 det the,segments
R4115 T6827 T6805 nsubjpass segments,reduced
R4116 T6828 T6827 amod outer,segments
R4117 T6829 T6805 auxpass were,reduced
R4118 T6830 T6805 prep by,reduced
R4119 T6831 T6832 nummod 50,%
R4120 T6832 T6830 pobj %,by
R4121 T6833 T6805 prep in,reduced
R4122 T6834 T6833 pobj length,in
R4123 T6835 T6805 punct .,reduced
R4124 T6837 T6838 advmod Also,perturbed
R4125 T6839 T6840 compound photoreceptor,terminals
R4126 T6840 T6838 nsubjpass terminals,perturbed
R4127 T6841 T6838 auxpass were,perturbed
R4128 T6842 T6838 prep in,perturbed
R4129 T6843 T6844 compound laminin,beta2
R4130 T6844 T6845 compound beta2,mutants
R4131 T6845 T6842 pobj mutants,in
R4132 T6846 T6838 punct ", ",perturbed
R4133 T6847 T6838 cc but,perturbed
R4134 T6848 T6849 advmod again,was
R4135 T6849 T6838 conj was,perturbed
R4136 T6850 T6851 det the,phenotype
R4137 T6851 T6849 nsubj phenotype,was
R4138 T6852 T6853 advmod more,subtle
R4139 T6853 T6849 acomp subtle,was
R4140 T6854 T6853 prep then,subtle
R4141 T6855 T6854 pobj that,then
R4142 T6856 T6855 prep of,that
R4143 T6857 T6858 nmod Crx,mice
R4144 T6858 T6856 pobj mice,of
R4145 T6859 T6857 punct -,Crx
R4146 T6860 T6857 punct /,Crx
R4147 T6861 T6857 punct -,Crx
R4148 T6862 T6849 punct .,was
R4149 T6864 T6865 det The,layer
R4150 T6865 T6868 nsubj layer,demonstrated
R4151 T6866 T6867 amod outer,plexiform
R4152 T6867 T6865 compound plexiform,layer
R4153 T6869 T6865 prep of,layer
R4154 T6870 T6871 det the,retinas
R4155 T6871 T6869 pobj retinas,of
R4156 T6872 T6873 npadvmod beta2,deficient
R4157 T6873 T6871 amod deficient,retinas
R4158 T6874 T6873 punct -,deficient
R4159 T6875 T6876 advmod only,7
R4160 T6876 T6877 nummod 7,%
R4161 T6877 T6878 nmod %,synapses
R4162 T6878 T6868 dobj synapses,demonstrated
R4163 T6879 T6878 amod normal,synapses
R4164 T6880 T6878 amod invaginating,synapses
R4165 T6881 T6868 punct ", ",demonstrated
R4166 T6882 T6883 mark while,had
R4167 T6883 T6868 advcl had,demonstrated
R4168 T6884 T6885 det the,remainder
R4169 T6885 T6883 nsubj remainder,had
R4170 T6886 T6887 amod various,pathologies
R4171 T6887 T6883 dobj pathologies,had
R4172 T6888 T6887 punct ", ",pathologies
R4173 T6889 T6887 prep including,pathologies
R4174 T6890 T6891 amod floating,ribbons
R4175 T6891 T6889 pobj ribbons,including
R4176 T6892 T6891 amod synaptic,ribbons
R4177 T6893 T6883 punct ", ",had
R4178 T6894 T6895 mark as,seen
R4179 T6895 T6883 advcl seen,had
R4180 T6896 T6895 advmod here,seen
R4181 T6897 T6868 punct .,demonstrated
R4182 T6899 T6900 det The,relationship
R4183 T6900 T6902 nsubj relationship,is
R4184 T6901 T6900 amod mechanistic,relationship
R4185 T6903 T6900 prep of,relationship
R4186 T6904 T6905 det these,molecules
R4187 T6905 T6903 pobj molecules,of
R4188 T6906 T6905 nummod two,molecules
R4189 T6907 T6908 punct ", ",any
R4190 T6908 T6900 parataxis any,relationship
R4191 T6909 T6908 mark if,any
R4192 T6910 T6908 punct ", ",any
R4193 T6911 T6900 prep in,relationship
R4194 T6912 T6913 compound photoreceptor,morphogenesis
R4195 T6913 T6911 pobj morphogenesis,in
R4196 T6914 T6902 acomp unknown,is
R4197 T6915 T6902 prep to,is
R4198 T6916 T6915 pobj date,to
R4199 T6917 T6902 punct .,is
R4200 T6919 T6920 det The,mRNA
R4201 T6920 T6921 nsubjpass mRNA,detected
R4202 T6922 T6920 prep for,mRNA
R4203 T6923 T6924 compound laminin,beta2
R4204 T6924 T6922 pobj beta2,for
R4205 T6925 T6921 auxpass was,detected
R4206 T6926 T6921 neg not,detected
R4207 T6927 T6921 prep in,detected
R4208 T6928 T6929 det the,study
R4209 T6929 T6927 pobj study,in
R4210 T6930 T6929 compound SAGE,study
R4211 T6931 T6929 prep of,study
R4212 T6932 T6933 det the,levels
R4213 T6933 T6931 pobj levels,of
R4214 T6934 T6933 amod relative,levels
R4215 T6935 T6933 compound RNA,levels
R4216 T6936 T6933 prep in,levels
R4217 T6937 T6936 pobj Crx,in
R4218 T6938 T6937 punct -,Crx
R4219 T6939 T6937 punct /,Crx
R4220 T6940 T6937 punct -,Crx
R4221 T6941 T6937 cc and,Crx
R4222 T6942 T6937 conj Crx,Crx
R4223 T6943 T6942 punct +,Crx
R4224 T6944 T6942 punct /,Crx
R4225 T6945 T6942 punct +,Crx
R4226 T6946 T6921 cc and,detected
R4227 T6947 T6948 advmod thus,comment
R4228 T6948 T6921 conj comment,detected
R4229 T6949 T6948 nsubj we,comment
R4230 T6950 T6948 aux can,comment
R4231 T6951 T6948 neg not,comment
R4232 T6952 T6948 prep on,comment
R4233 T6953 T6954 mark whether,altered
R4234 T6954 T6952 pcomp altered,on
R4235 T6955 T6956 det the,levels
R4236 T6956 T6954 nsubjpass levels,altered
R4237 T6957 T6956 prep of,levels
R4238 T6958 T6957 pobj RNA,of
R4239 T6959 T6956 prep for,levels
R4240 T6960 T6961 compound laminin,beta2
R4241 T6961 T6959 pobj beta2,for
R4242 T6962 T6954 auxpass were,altered
R4243 T6963 T6948 punct .,comment