PMC:539297 / 25325-25810 4 Projects
Annnotations
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5047 | 0-3 | DT | denotes | The |
T5049 | 4-12 | NN | denotes | membrane |
T5048 | 13-24 | NN | denotes | trafficking |
T5051 | 25-28 | CC | denotes | and |
T5052 | 29-42 | JJ | denotes | mitochondrial |
T5053 | 43-51 | NNS | denotes | deficits |
T5054 | 52-61 | VBN | denotes | uncovered |
T5055 | 62-64 | IN | denotes | in |
T5056 | 65-75 | JJ | denotes | homozygous |
T5058 | 76-86 | NN | denotes | CbCln3Δex7 |
T5059 | 86-87 | HYPH | denotes | / |
T5060 | 87-88 | CD | denotes | 8 |
T5057 | 89-94 | NNS | denotes | cells |
T5050 | 95-98 | VBP | denotes | are |
T5061 | 99-105 | JJ | denotes | likely |
T5062 | 106-108 | TO | denotes | to |
T5064 | 109-121 | RB | denotes | particularly |
T5063 | 122-128 | VB | denotes | impact |
T5065 | 129-137 | JJ | denotes | neuronal |
T5066 | 138-146 | NN | denotes | function |
T5067 | 146-147 | . | denotes | . |
T5068 | 147-304 | sentence | denotes | Neurotransmission heavily relies on membrane vesicle transport, and a high-energy metabolism may further sensitize neurons to the loss of battenin activity. |
T5069 | 148-165 | NN | denotes | Neurotransmission |
T5071 | 166-173 | RB | denotes | heavily |
T5070 | 174-180 | VBZ | denotes | relies |
T5072 | 181-183 | IN | denotes | on |
T5073 | 184-192 | NN | denotes | membrane |
T5074 | 193-200 | NN | denotes | vesicle |
T5075 | 201-210 | NN | denotes | transport |
T5076 | 210-212 | , | denotes | , |
T5077 | 212-215 | CC | denotes | and |
T5078 | 216-217 | DT | denotes | a |
T5080 | 218-222 | JJ | denotes | high |
T5082 | 222-223 | HYPH | denotes | - |
T5081 | 223-229 | NN | denotes | energy |
T5079 | 230-240 | NN | denotes | metabolism |
T5084 | 241-244 | MD | denotes | may |
T5085 | 245-252 | RB | denotes | further |
T5083 | 253-262 | VB | denotes | sensitize |
T5086 | 263-270 | NNS | denotes | neurons |
T5087 | 271-273 | IN | denotes | to |
T5088 | 274-277 | DT | denotes | the |
T5089 | 278-282 | NN | denotes | loss |
T5090 | 283-285 | IN | denotes | of |
T5091 | 286-294 | NN | denotes | battenin |
T5092 | 295-303 | NN | denotes | activity |
T5093 | 303-304 | . | denotes | . |
T5094 | 304-485 | sentence | denotes | Thus, our panel of wild-type, heterozygous, and homozygous CbCln3Δex7/8 cerebellar cells provide an ideal model system to further elucidate battenin function and JNCL pathogenesis. |
T5095 | 305-309 | RB | denotes | Thus |
T5097 | 309-311 | , | denotes | , |
T5098 | 311-314 | PRP$ | denotes | our |
T5099 | 315-320 | NN | denotes | panel |
T5100 | 321-323 | IN | denotes | of |
T5101 | 324-328 | JJ | denotes | wild |
T5103 | 328-329 | HYPH | denotes | - |
T5102 | 329-333 | NN | denotes | type |
T5105 | 333-335 | , | denotes | , |
T5106 | 335-347 | JJ | denotes | heterozygous |
T5107 | 347-349 | , | denotes | , |
T5108 | 349-352 | CC | denotes | and |
T5109 | 353-363 | JJ | denotes | homozygous |
T5110 | 364-374 | NN | denotes | CbCln3Δex7 |
T5111 | 374-375 | HYPH | denotes | / |
T5112 | 375-376 | CD | denotes | 8 |
T5113 | 377-387 | JJ | denotes | cerebellar |
T5104 | 388-393 | NNS | denotes | cells |
T5096 | 394-401 | VBP | denotes | provide |
T5114 | 402-404 | DT | denotes | an |
T5116 | 405-410 | JJ | denotes | ideal |
T5117 | 411-416 | NN | denotes | model |
T5115 | 417-423 | NN | denotes | system |
T5118 | 424-426 | TO | denotes | to |
T5120 | 427-434 | RBR | denotes | further |
T5119 | 435-444 | VB | denotes | elucidate |
T5121 | 445-453 | NN | denotes | battenin |
T5122 | 454-462 | NN | denotes | function |
T5123 | 463-466 | CC | denotes | and |
T5124 | 467-471 | NN | denotes | JNCL |
T5125 | 472-484 | NN | denotes | pathogenesis |
T5126 | 484-485 | . | denotes | . |
R2925 | T5047 | T5048 | det | The,trafficking |
R2926 | T5048 | T5050 | nsubj | trafficking,are |
R2927 | T5049 | T5048 | compound | membrane,trafficking |
R2928 | T5051 | T5048 | cc | and,trafficking |
R2929 | T5052 | T5053 | amod | mitochondrial,deficits |
R2930 | T5053 | T5048 | conj | deficits,trafficking |
R2931 | T5054 | T5048 | acl | uncovered,trafficking |
R2932 | T5055 | T5054 | prep | in,uncovered |
R2933 | T5056 | T5057 | amod | homozygous,cells |
R2934 | T5057 | T5055 | pobj | cells,in |
R2935 | T5058 | T5057 | nmod | CbCln3Δex7,cells |
R2936 | T5059 | T5058 | punct | /,CbCln3Δex7 |
R2937 | T5060 | T5058 | nummod | 8,CbCln3Δex7 |
R2938 | T5061 | T5050 | acomp | likely,are |
R2939 | T5062 | T5063 | aux | to,impact |
R2940 | T5063 | T5061 | xcomp | impact,likely |
R2941 | T5064 | T5063 | advmod | particularly,impact |
R2942 | T5065 | T5066 | amod | neuronal,function |
R2943 | T5066 | T5063 | dobj | function,impact |
R2944 | T5067 | T5050 | punct | .,are |
R2945 | T5069 | T5070 | nsubj | Neurotransmission,relies |
R2946 | T5071 | T5070 | advmod | heavily,relies |
R2947 | T5072 | T5070 | prep | on,relies |
R2948 | T5073 | T5074 | compound | membrane,vesicle |
R2949 | T5074 | T5075 | compound | vesicle,transport |
R2950 | T5075 | T5072 | pobj | transport,on |
R2951 | T5076 | T5070 | punct | ", ",relies |
R2952 | T5077 | T5070 | cc | and,relies |
R2953 | T5078 | T5079 | det | a,metabolism |
R2954 | T5079 | T5083 | nsubj | metabolism,sensitize |
R2955 | T5080 | T5081 | amod | high,energy |
R2956 | T5081 | T5079 | compound | energy,metabolism |
R2957 | T5082 | T5081 | punct | -,energy |
R2958 | T5083 | T5070 | conj | sensitize,relies |
R2959 | T5084 | T5083 | aux | may,sensitize |
R2960 | T5085 | T5083 | advmod | further,sensitize |
R2961 | T5086 | T5083 | dobj | neurons,sensitize |
R2962 | T5087 | T5083 | prep | to,sensitize |
R2963 | T5088 | T5089 | det | the,loss |
R2964 | T5089 | T5087 | pobj | loss,to |
R2965 | T5090 | T5089 | prep | of,loss |
R2966 | T5091 | T5092 | compound | battenin,activity |
R2967 | T5092 | T5090 | pobj | activity,of |
R2968 | T5093 | T5083 | punct | .,sensitize |
R2969 | T5095 | T5096 | advmod | Thus,provide |
R2970 | T5097 | T5096 | punct | ", ",provide |
R2971 | T5098 | T5099 | poss | our,panel |
R2972 | T5099 | T5096 | nsubj | panel,provide |
R2973 | T5100 | T5099 | prep | of,panel |
R2974 | T5101 | T5102 | amod | wild,type |
R2975 | T5102 | T5104 | nmod | type,cells |
R2976 | T5103 | T5102 | punct | -,type |
R2977 | T5104 | T5100 | pobj | cells,of |
R2978 | T5105 | T5102 | punct | ", ",type |
R2979 | T5106 | T5102 | conj | heterozygous,type |
R2980 | T5107 | T5106 | punct | ", ",heterozygous |
R2981 | T5108 | T5106 | cc | and,heterozygous |
R2982 | T5109 | T5106 | conj | homozygous,heterozygous |
R2983 | T5110 | T5104 | nmod | CbCln3Δex7,cells |
R2984 | T5111 | T5110 | punct | /,CbCln3Δex7 |
R2985 | T5112 | T5110 | nummod | 8,CbCln3Δex7 |
R2986 | T5113 | T5104 | amod | cerebellar,cells |
R2987 | T5114 | T5115 | det | an,system |
R2988 | T5115 | T5096 | dobj | system,provide |
R2989 | T5116 | T5115 | amod | ideal,system |
R2990 | T5117 | T5115 | compound | model,system |
R2991 | T5118 | T5119 | aux | to,elucidate |
R2992 | T5119 | T5115 | advcl | elucidate,system |
R2993 | T5120 | T5119 | advmod | further,elucidate |
R2994 | T5121 | T5122 | compound | battenin,function |
R2995 | T5122 | T5119 | dobj | function,elucidate |
R2996 | T5123 | T5122 | cc | and,function |
R2997 | T5124 | T5125 | compound | JNCL,pathogenesis |
R2998 | T5125 | T5122 | conj | pathogenesis,function |
R2999 | T5126 | T5096 | punct | .,provide |