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PMC:539061 / 55199-56079 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T11761 0-12 JJ denotes Irrespective
T11763 13-15 IN denotes of
T11764 16-21 DT denotes these
T11765 22-33 NNS denotes differences
T11766 33-35 , denotes ,
T11767 35-38 PRP$ denotes our
T11769 39-41 FW denotes in
T11770 42-46 FW denotes vivo
T11768 47-54 NNS denotes studies
T11771 55-57 VBP denotes do
T11772 58-61 RB denotes not
T11762 62-67 VB denotes stand
T11773 68-73 RB denotes alone
T11774 73-75 , denotes ,
T11775 75-77 IN denotes as
T11777 78-83 EX denotes there
T11776 84-87 VBP denotes are
T11778 88-92 JJ denotes many
T11779 93-103 NNS denotes situations
T11780 104-106 IN denotes in
T11782 107-112 WDT denotes which
T11783 113-114 DT denotes a
T11785 115-119 JJ denotes down
T11786 119-120 HYPH denotes -
T11784 120-130 NN denotes regulation
T11787 131-133 IN denotes in
T11788 134-136 NN denotes AJ
T11789 137-145 NN denotes proteins
T11781 146-155 VBP denotes correlate
T11790 156-160 IN denotes with
T11791 161-169 VBN denotes enhanced
T11792 170-183 NN denotes proliferation
T11793 183-184 . denotes .
T11794 184-334 sentence denotes In fact, a myriad of diverse mechanisms have been implicated in activating epithelial proliferation upon down-regulation of AJ proteins [7,23,24,48].
T11795 185-187 IN denotes In
T11797 188-192 NN denotes fact
T11798 192-194 , denotes ,
T11799 194-195 DT denotes a
T11800 196-202 NN denotes myriad
T11801 203-205 IN denotes of
T11802 206-213 JJ denotes diverse
T11803 214-224 NNS denotes mechanisms
T11804 225-229 VBP denotes have
T11805 230-234 VBN denotes been
T11796 235-245 VBN denotes implicated
T11806 246-248 IN denotes in
T11807 249-259 VBG denotes activating
T11808 260-270 JJ denotes epithelial
T11809 271-284 NN denotes proliferation
T11810 285-289 IN denotes upon
T11811 290-294 JJ denotes down
T11813 294-295 HYPH denotes -
T11812 295-305 NN denotes regulation
T11814 306-308 IN denotes of
T11815 309-311 NN denotes AJ
T11816 312-320 NN denotes proteins
T11817 321-322 -LRB- denotes [
T11819 322-323 CD denotes 7
T11820 323-324 , denotes ,
T11821 324-326 CD denotes 23
T11822 326-327 , denotes ,
T11823 327-329 CD denotes 24
T11824 329-330 , denotes ,
T11818 330-332 CD denotes 48
T11825 332-333 -RRB- denotes ]
T11826 333-334 . denotes .
T11827 334-429 sentence denotes Sifting through these converging pathways is likely to be a difficult and painstaking process.
T11828 335-342 VBG denotes Sifting
T11830 343-350 IN denotes through
T11831 351-356 DT denotes these
T11833 357-367 VBG denotes converging
T11832 368-376 NNS denotes pathways
T11829 377-379 VBZ denotes is
T11834 380-386 JJ denotes likely
T11835 387-389 TO denotes to
T11836 390-392 VB denotes be
T11837 393-394 DT denotes a
T11839 395-404 JJ denotes difficult
T11840 405-408 CC denotes and
T11841 409-420 JJ denotes painstaking
T11838 421-428 NN denotes process
T11842 428-429 . denotes .
T11843 429-714 sentence denotes This said, by identifying the status of different players involved in specific cell types and at specific stages in development, our mechanistic understanding of how intercellular remodeling is linked to proliferation in epithelial morphogenesis should begin to surface in the future.
T11844 430-434 DT denotes This
T11845 435-439 VBD denotes said
T11847 439-441 , denotes ,
T11848 441-443 IN denotes by
T11849 444-455 VBG denotes identifying
T11850 456-459 DT denotes the
T11851 460-466 NN denotes status
T11852 467-469 IN denotes of
T11853 470-479 JJ denotes different
T11854 480-487 NNS denotes players
T11855 488-496 VBN denotes involved
T11856 497-499 IN denotes in
T11857 500-508 JJ denotes specific
T11859 509-513 NN denotes cell
T11858 514-519 NNS denotes types
T11860 520-523 CC denotes and
T11861 524-526 IN denotes at
T11862 527-535 JJ denotes specific
T11863 536-542 NNS denotes stages
T11864 543-545 IN denotes in
T11865 546-557 NN denotes development
T11866 557-559 , denotes ,
T11867 559-562 PRP$ denotes our
T11869 563-574 JJ denotes mechanistic
T11868 575-588 NN denotes understanding
T11870 589-591 IN denotes of
T11871 592-595 WRB denotes how
T11873 596-609 JJ denotes intercellular
T11874 610-620 NN denotes remodeling
T11875 621-623 VBZ denotes is
T11872 624-630 VBN denotes linked
T11876 631-633 IN denotes to
T11877 634-647 NN denotes proliferation
T11878 648-650 IN denotes in
T11879 651-661 JJ denotes epithelial
T11880 662-675 NN denotes morphogenesis
T11881 676-682 MD denotes should
T11846 683-688 VB denotes begin
T11882 689-691 TO denotes to
T11883 692-699 VB denotes surface
T11884 700-702 IN denotes in
T11885 703-706 DT denotes the
T11886 707-713 NN denotes future
T11887 713-714 . denotes .
T11888 714-880 sentence denotes Elucidating the molecular mechanisms through which these networks converge is also a prerequisite for understanding how these processes go awry during tumorigenesis.
T11889 715-726 VBG denotes Elucidating
T11891 727-730 DT denotes the
T11893 731-740 JJ denotes molecular
T11892 741-751 NNS denotes mechanisms
T11894 752-759 IN denotes through
T11896 760-765 WDT denotes which
T11897 766-771 DT denotes these
T11898 772-780 NNS denotes networks
T11895 781-789 VBP denotes converge
T11890 790-792 VBZ denotes is
T11899 793-797 RB denotes also
T11900 798-799 DT denotes a
T11901 800-812 NN denotes prerequisite
T11902 813-816 IN denotes for
T11903 817-830 VBG denotes understanding
T11904 831-834 WRB denotes how
T11906 835-840 DT denotes these
T11907 841-850 NNS denotes processes
T11905 851-853 VBP denotes go
T11908 854-858 RB denotes awry
T11909 859-865 IN denotes during
T11910 866-879 NN denotes tumorigenesis
T11911 879-880 . denotes .
R7540 T11761 T11762 advcl Irrespective,stand
R7541 T11763 T11761 prep of,Irrespective
R7542 T11764 T11765 det these,differences
R7543 T11765 T11763 pobj differences,of
R7544 T11766 T11762 punct ", ",stand
R7545 T11767 T11768 poss our,studies
R7546 T11768 T11762 nsubj studies,stand
R7547 T11769 T11770 advmod in,vivo
R7548 T11770 T11768 amod vivo,studies
R7549 T11771 T11762 aux do,stand
R7550 T11772 T11762 neg not,stand
R7551 T11773 T11762 advmod alone,stand
R7552 T11774 T11762 punct ", ",stand
R7553 T11775 T11776 mark as,are
R7554 T11776 T11762 advcl are,stand
R7555 T11777 T11776 expl there,are
R7556 T11778 T11779 amod many,situations
R7557 T11779 T11776 attr situations,are
R7558 T11780 T11781 prep in,correlate
R7559 T11781 T11779 relcl correlate,situations
R7560 T11782 T11780 pobj which,in
R7561 T11783 T11784 det a,regulation
R7562 T11784 T11781 nsubj regulation,correlate
R7563 T11785 T11784 amod down,regulation
R7564 T11786 T11784 punct -,regulation
R7565 T11787 T11784 prep in,regulation
R7566 T11788 T11789 compound AJ,proteins
R7567 T11789 T11787 pobj proteins,in
R7568 T11790 T11781 prep with,correlate
R7569 T11791 T11792 amod enhanced,proliferation
R7570 T11792 T11790 pobj proliferation,with
R7571 T11793 T11762 punct .,stand
R7572 T11795 T11796 prep In,implicated
R7573 T11797 T11795 pobj fact,In
R7574 T11798 T11796 punct ", ",implicated
R7575 T11799 T11800 det a,myriad
R7576 T11800 T11796 nsubjpass myriad,implicated
R7577 T11801 T11800 prep of,myriad
R7578 T11802 T11803 amod diverse,mechanisms
R7579 T11803 T11801 pobj mechanisms,of
R7580 T11804 T11796 aux have,implicated
R7581 T11805 T11796 auxpass been,implicated
R7582 T11806 T11796 prep in,implicated
R7583 T11807 T11806 pcomp activating,in
R7584 T11808 T11809 amod epithelial,proliferation
R7585 T11809 T11807 dobj proliferation,activating
R7586 T11810 T11807 prep upon,activating
R7587 T11811 T11812 amod down,regulation
R7588 T11812 T11810 pobj regulation,upon
R7589 T11813 T11812 punct -,regulation
R7590 T11814 T11812 prep of,regulation
R7591 T11815 T11816 compound AJ,proteins
R7592 T11816 T11814 pobj proteins,of
R7593 T11817 T11818 punct [,48
R7594 T11818 T11796 parataxis 48,implicated
R7595 T11819 T11818 nummod 7,48
R7596 T11820 T11818 punct ",",48
R7597 T11821 T11818 nummod 23,48
R7598 T11822 T11818 punct ",",48
R7599 T11823 T11818 nummod 24,48
R7600 T11824 T11818 punct ",",48
R7601 T11825 T11818 punct ],48
R7602 T11826 T11796 punct .,implicated
R7603 T11828 T11829 csubj Sifting,is
R7604 T11830 T11828 prep through,Sifting
R7605 T11831 T11832 det these,pathways
R7606 T11832 T11830 pobj pathways,through
R7607 T11833 T11832 amod converging,pathways
R7608 T11834 T11829 acomp likely,is
R7609 T11835 T11836 aux to,be
R7610 T11836 T11834 xcomp be,likely
R7611 T11837 T11838 det a,process
R7612 T11838 T11836 attr process,be
R7613 T11839 T11838 amod difficult,process
R7614 T11840 T11839 cc and,difficult
R7615 T11841 T11839 conj painstaking,difficult
R7616 T11842 T11829 punct .,is
R7617 T11844 T11845 nsubj This,said
R7618 T11845 T11846 advcl said,begin
R7619 T11847 T11846 punct ", ",begin
R7620 T11848 T11846 prep by,begin
R7621 T11849 T11848 pcomp identifying,by
R7622 T11850 T11851 det the,status
R7623 T11851 T11849 dobj status,identifying
R7624 T11852 T11851 prep of,status
R7625 T11853 T11854 amod different,players
R7626 T11854 T11852 pobj players,of
R7627 T11855 T11854 acl involved,players
R7628 T11856 T11849 prep in,identifying
R7629 T11857 T11858 amod specific,types
R7630 T11858 T11856 pobj types,in
R7631 T11859 T11858 compound cell,types
R7632 T11860 T11856 cc and,in
R7633 T11861 T11856 conj at,in
R7634 T11862 T11863 amod specific,stages
R7635 T11863 T11861 pobj stages,at
R7636 T11864 T11863 prep in,stages
R7637 T11865 T11864 pobj development,in
R7638 T11866 T11846 punct ", ",begin
R7639 T11867 T11868 poss our,understanding
R7640 T11868 T11846 nsubj understanding,begin
R7641 T11869 T11868 amod mechanistic,understanding
R7642 T11870 T11868 prep of,understanding
R7643 T11871 T11872 advmod how,linked
R7644 T11872 T11870 pcomp linked,of
R7645 T11873 T11874 amod intercellular,remodeling
R7646 T11874 T11872 nsubjpass remodeling,linked
R7647 T11875 T11872 auxpass is,linked
R7648 T11876 T11872 prep to,linked
R7649 T11877 T11876 pobj proliferation,to
R7650 T11878 T11872 prep in,linked
R7651 T11879 T11880 amod epithelial,morphogenesis
R7652 T11880 T11878 pobj morphogenesis,in
R7653 T11881 T11846 aux should,begin
R7654 T11882 T11883 aux to,surface
R7655 T11883 T11846 xcomp surface,begin
R7656 T11884 T11883 prep in,surface
R7657 T11885 T11886 det the,future
R7658 T11886 T11884 pobj future,in
R7659 T11887 T11846 punct .,begin
R7660 T11889 T11890 csubj Elucidating,is
R7661 T11891 T11892 det the,mechanisms
R7662 T11892 T11889 dobj mechanisms,Elucidating
R7663 T11893 T11892 amod molecular,mechanisms
R7664 T11894 T11895 prep through,converge
R7665 T11895 T11892 relcl converge,mechanisms
R7666 T11896 T11894 pobj which,through
R7667 T11897 T11898 det these,networks
R7668 T11898 T11895 nsubj networks,converge
R7669 T11899 T11890 advmod also,is
R7670 T11900 T11901 det a,prerequisite
R7671 T11901 T11890 attr prerequisite,is
R7672 T11902 T11901 prep for,prerequisite
R7673 T11903 T11902 pcomp understanding,for
R7674 T11904 T11905 advmod how,go
R7675 T11905 T11903 ccomp go,understanding
R7676 T11906 T11907 det these,processes
R7677 T11907 T11905 nsubj processes,go
R7678 T11908 T11905 advmod awry,go
R7679 T11909 T11905 prep during,go
R7680 T11910 T11909 pobj tumorigenesis,during
R7681 T11911 T11890 punct .,is