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PMC:539061 / 29652-30517 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T5743 0-3 DT denotes The
T5744 4-16 NNS denotes similarities
T5746 17-24 IN denotes between
T5747 25-30 NN denotes Snail
T5749 31-33 NN denotes Tg
T5748 34-43 NN denotes epidermis
T5750 44-47 CC denotes and
T5751 48-52 NN denotes hair
T5752 53-57 NNS denotes buds
T5745 58-66 VBD denotes extended
T5753 67-69 IN denotes to
T5754 70-73 DT denotes the
T5756 74-92 JJ denotes hyperproliferative
T5755 93-98 NN denotes state
T5757 98-100 , denotes ,
T5758 100-107 VBG denotes leading
T5759 108-110 PRP denotes us
T5760 111-113 TO denotes to
T5761 114-120 VB denotes wonder
T5762 121-128 IN denotes whether
T5764 129-132 DT denotes the
T5766 133-137 JJ denotes down
T5767 137-138 HYPH denotes -
T5765 138-148 NN denotes regulation
T5768 149-151 IN denotes of
T5769 152-154 NN denotes AJ
T5770 155-163 NN denotes proteins
T5771 164-169 MD denotes might
T5763 170-180 VB denotes contribute
T5772 181-183 IN denotes to
T5773 184-188 DT denotes this
T5774 189-198 NN denotes condition
T5775 198-199 . denotes .
T5776 199-409 sentence denotes Given the increase in pMAPK staining in Snail Tg epidermis (see Figure 2G), we used pMAPK levels as our assay to test whether the loss of E-cadherin contributed to the Snail-mediated increase in proliferation.
T5777 200-205 VBN denotes Given
T5779 206-209 DT denotes the
T5780 210-218 NN denotes increase
T5781 219-221 IN denotes in
T5782 222-227 NN denotes pMAPK
T5783 228-236 NN denotes staining
T5784 237-239 IN denotes in
T5785 240-245 NN denotes Snail
T5787 246-248 NN denotes Tg
T5786 249-258 NN denotes epidermis
T5788 259-260 -LRB- denotes (
T5789 260-263 VB denotes see
T5790 264-270 NN denotes Figure
T5791 271-273 NN denotes 2G
T5792 273-274 -RRB- denotes )
T5793 274-276 , denotes ,
T5794 276-278 PRP denotes we
T5778 279-283 VBD denotes used
T5795 284-289 NN denotes pMAPK
T5796 290-296 NNS denotes levels
T5797 297-299 IN denotes as
T5798 300-303 PRP$ denotes our
T5799 304-309 NN denotes assay
T5800 310-312 TO denotes to
T5801 313-317 VB denotes test
T5802 318-325 IN denotes whether
T5804 326-329 DT denotes the
T5805 330-334 NN denotes loss
T5806 335-337 IN denotes of
T5807 338-339 NN denotes E
T5809 339-340 HYPH denotes -
T5808 340-348 NN denotes cadherin
T5803 349-360 VBD denotes contributed
T5810 361-363 IN denotes to
T5811 364-367 DT denotes the
T5813 368-373 NN denotes Snail
T5815 373-374 HYPH denotes -
T5814 374-382 VBN denotes mediated
T5812 383-391 NN denotes increase
T5816 392-394 IN denotes in
T5817 395-408 NN denotes proliferation
T5818 408-409 . denotes .
T5819 409-582 sentence denotes Consistent with our in vivo observations, transfected keratinocytes expressing Snail exhibited a substantial increase in pMAPK levels relative to control cells (Figure 4D).
T5820 410-420 JJ denotes Consistent
T5822 421-425 IN denotes with
T5823 426-429 PRP$ denotes our
T5825 430-432 FW denotes in
T5826 433-437 FW denotes vivo
T5824 438-450 NNS denotes observations
T5827 450-452 , denotes ,
T5828 452-463 VBN denotes transfected
T5829 464-477 NNS denotes keratinocytes
T5830 478-488 VBG denotes expressing
T5831 489-494 NN denotes Snail
T5821 495-504 VBD denotes exhibited
T5832 505-506 DT denotes a
T5834 507-518 JJ denotes substantial
T5833 519-527 NN denotes increase
T5835 528-530 IN denotes in
T5836 531-536 NN denotes pMAPK
T5837 537-543 NNS denotes levels
T5838 544-552 JJ denotes relative
T5839 553-555 IN denotes to
T5840 556-563 NN denotes control
T5841 564-569 NNS denotes cells
T5842 570-571 -LRB- denotes (
T5844 571-577 NN denotes Figure
T5843 578-580 NN denotes 4D
T5845 580-581 -RRB- denotes )
T5846 581-582 . denotes .
T5847 582-654 sentence denotes Coexpression of E-cadherin with Snail appeared to abrogate this effect.
T5848 583-595 NN denotes Coexpression
T5850 596-598 IN denotes of
T5851 599-600 NN denotes E
T5853 600-601 HYPH denotes -
T5852 601-609 NN denotes cadherin
T5854 610-614 IN denotes with
T5855 615-620 NN denotes Snail
T5849 621-629 VBD denotes appeared
T5856 630-632 TO denotes to
T5857 633-641 VB denotes abrogate
T5858 642-646 DT denotes this
T5859 647-653 NN denotes effect
T5860 653-654 . denotes .
T5861 654-865 sentence denotes Together, these findings raised the possibility that an AJ-associated protein that is normally sequestered at the plasma membrane may participate in a proliferation signaling pathway when AJs are deconstructed.
T5862 655-663 RB denotes Together
T5864 663-665 , denotes ,
T5865 665-670 DT denotes these
T5866 671-679 NNS denotes findings
T5863 680-686 VBD denotes raised
T5867 687-690 DT denotes the
T5868 691-702 NN denotes possibility
T5869 703-707 IN denotes that
T5871 708-710 DT denotes an
T5873 711-713 NN denotes AJ
T5875 713-714 HYPH denotes -
T5874 714-724 VBN denotes associated
T5872 725-732 NN denotes protein
T5876 733-737 WDT denotes that
T5878 738-740 VBZ denotes is
T5879 741-749 RB denotes normally
T5877 750-761 VBN denotes sequestered
T5880 762-764 IN denotes at
T5881 765-768 DT denotes the
T5883 769-775 NN denotes plasma
T5882 776-784 NN denotes membrane
T5884 785-788 MD denotes may
T5870 789-800 VB denotes participate
T5885 801-803 IN denotes in
T5886 804-805 DT denotes a
T5888 806-819 NN denotes proliferation
T5889 820-829 NN denotes signaling
T5887 830-837 NN denotes pathway
T5890 838-842 WRB denotes when
T5892 843-846 NNS denotes AJs
T5893 847-850 VBP denotes are
T5891 851-864 VBN denotes deconstructed
T5894 864-865 . denotes .
R3369 T5743 T5744 det The,similarities
R3370 T5744 T5745 nsubj similarities,extended
R3371 T5746 T5744 prep between,similarities
R3372 T5747 T5748 compound Snail,epidermis
R3373 T5748 T5746 pobj epidermis,between
R3374 T5749 T5748 compound Tg,epidermis
R3375 T5750 T5748 cc and,epidermis
R3376 T5751 T5752 compound hair,buds
R3377 T5752 T5748 conj buds,epidermis
R3378 T5753 T5745 prep to,extended
R3379 T5754 T5755 det the,state
R3380 T5755 T5753 pobj state,to
R3381 T5756 T5755 amod hyperproliferative,state
R3382 T5757 T5745 punct ", ",extended
R3383 T5758 T5745 advcl leading,extended
R3384 T5759 T5758 dobj us,leading
R3385 T5760 T5761 aux to,wonder
R3386 T5761 T5758 xcomp wonder,leading
R3387 T5762 T5763 mark whether,contribute
R3388 T5763 T5761 ccomp contribute,wonder
R3389 T5764 T5765 det the,regulation
R3390 T5765 T5763 nsubj regulation,contribute
R3391 T5766 T5765 amod down,regulation
R3392 T5767 T5765 punct -,regulation
R3393 T5768 T5765 prep of,regulation
R3394 T5769 T5770 compound AJ,proteins
R3395 T5770 T5768 pobj proteins,of
R3396 T5771 T5763 aux might,contribute
R3397 T5772 T5763 prep to,contribute
R3398 T5773 T5774 det this,condition
R3399 T5774 T5772 pobj condition,to
R3400 T5775 T5745 punct .,extended
R3401 T5777 T5778 prep Given,used
R3402 T5779 T5780 det the,increase
R3403 T5780 T5777 pobj increase,Given
R3404 T5781 T5780 prep in,increase
R3405 T5782 T5783 compound pMAPK,staining
R3406 T5783 T5781 pobj staining,in
R3407 T5784 T5780 prep in,increase
R3408 T5785 T5786 compound Snail,epidermis
R3409 T5786 T5784 pobj epidermis,in
R3410 T5787 T5786 compound Tg,epidermis
R3411 T5788 T5789 punct (,see
R3412 T5789 T5780 parataxis see,increase
R3413 T5790 T5791 compound Figure,2G
R3414 T5791 T5789 dobj 2G,see
R3415 T5792 T5789 punct ),see
R3416 T5793 T5778 punct ", ",used
R3417 T5794 T5778 nsubj we,used
R3418 T5795 T5796 compound pMAPK,levels
R3419 T5796 T5778 dobj levels,used
R3420 T5797 T5778 prep as,used
R3421 T5798 T5799 poss our,assay
R3422 T5799 T5797 pobj assay,as
R3423 T5800 T5801 aux to,test
R3424 T5801 T5778 advcl test,used
R3425 T5802 T5803 mark whether,contributed
R3426 T5803 T5801 ccomp contributed,test
R3427 T5804 T5805 det the,loss
R3428 T5805 T5803 nsubj loss,contributed
R3429 T5806 T5805 prep of,loss
R3430 T5807 T5808 compound E,cadherin
R3431 T5808 T5806 pobj cadherin,of
R3432 T5809 T5808 punct -,cadherin
R3433 T5810 T5803 prep to,contributed
R3434 T5811 T5812 det the,increase
R3435 T5812 T5810 pobj increase,to
R3436 T5813 T5814 npadvmod Snail,mediated
R3437 T5814 T5812 amod mediated,increase
R3438 T5815 T5814 punct -,mediated
R3439 T5816 T5812 prep in,increase
R3440 T5817 T5816 pobj proliferation,in
R3441 T5818 T5778 punct .,used
R3442 T5820 T5821 advcl Consistent,exhibited
R3443 T5822 T5820 prep with,Consistent
R3444 T5823 T5824 poss our,observations
R3445 T5824 T5822 pobj observations,with
R3446 T5825 T5826 advmod in,vivo
R3447 T5826 T5824 amod vivo,observations
R3448 T5827 T5821 punct ", ",exhibited
R3449 T5828 T5829 amod transfected,keratinocytes
R3450 T5829 T5821 nsubj keratinocytes,exhibited
R3451 T5830 T5829 acl expressing,keratinocytes
R3452 T5831 T5830 dobj Snail,expressing
R3453 T5832 T5833 det a,increase
R3454 T5833 T5821 dobj increase,exhibited
R3455 T5834 T5833 amod substantial,increase
R3456 T5835 T5833 prep in,increase
R3457 T5836 T5837 compound pMAPK,levels
R3458 T5837 T5835 pobj levels,in
R3459 T5838 T5833 amod relative,increase
R3460 T5839 T5838 prep to,relative
R3461 T5840 T5841 compound control,cells
R3462 T5841 T5839 pobj cells,to
R3463 T5842 T5843 punct (,4D
R3464 T5843 T5821 parataxis 4D,exhibited
R3465 T5844 T5843 compound Figure,4D
R3466 T5845 T5843 punct ),4D
R3467 T5846 T5821 punct .,exhibited
R3468 T5848 T5849 nsubj Coexpression,appeared
R3469 T5850 T5848 prep of,Coexpression
R3470 T5851 T5852 compound E,cadherin
R3471 T5852 T5850 pobj cadherin,of
R3472 T5853 T5852 punct -,cadherin
R3473 T5854 T5848 prep with,Coexpression
R3474 T5855 T5854 pobj Snail,with
R3475 T5856 T5857 aux to,abrogate
R3476 T5857 T5849 xcomp abrogate,appeared
R3477 T5858 T5859 det this,effect
R3478 T5859 T5857 dobj effect,abrogate
R3479 T5860 T5849 punct .,appeared
R3480 T5862 T5863 advmod Together,raised
R3481 T5864 T5863 punct ", ",raised
R3482 T5865 T5866 det these,findings
R3483 T5866 T5863 nsubj findings,raised
R3484 T5867 T5868 det the,possibility
R3485 T5868 T5863 dobj possibility,raised
R3486 T5869 T5870 mark that,participate
R3487 T5870 T5868 acl participate,possibility
R3488 T5871 T5872 det an,protein
R3489 T5872 T5870 nsubj protein,participate
R3490 T5873 T5874 npadvmod AJ,associated
R3491 T5874 T5872 amod associated,protein
R3492 T5875 T5874 punct -,associated
R3493 T5876 T5877 dep that,sequestered
R3494 T5877 T5872 relcl sequestered,protein
R3495 T5878 T5877 auxpass is,sequestered
R3496 T5879 T5877 advmod normally,sequestered
R3497 T5880 T5877 prep at,sequestered
R3498 T5881 T5882 det the,membrane
R3499 T5882 T5880 pobj membrane,at
R3500 T5883 T5882 compound plasma,membrane
R3501 T5884 T5870 aux may,participate
R3502 T5885 T5870 prep in,participate
R3503 T5886 T5887 det a,pathway
R3504 T5887 T5885 pobj pathway,in
R3505 T5888 T5887 compound proliferation,pathway
R3506 T5889 T5887 compound signaling,pathway
R3507 T5890 T5891 advmod when,deconstructed
R3508 T5891 T5870 advcl deconstructed,participate
R3509 T5892 T5891 nsubjpass AJs,deconstructed
R3510 T5893 T5891 auxpass are,deconstructed
R3511 T5894 T5863 punct .,raised