| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T2341 |
0-4 |
NNS |
denotes |
Mice |
| T2343 |
5-12 |
VBG |
denotes |
lacking |
| T2344 |
13-25 |
JJ |
denotes |
proapoptotic |
| T2346 |
26-33 |
NN |
denotes |
protein |
| T2345 |
34-37 |
NN |
denotes |
Bax |
| T2342 |
38-43 |
VBP |
denotes |
allow |
| T2347 |
44-47 |
IN |
denotes |
for |
| T2348 |
48-62 |
VBG |
denotes |
distinguishing |
| T2349 |
63-71 |
NN |
denotes |
survival |
| T2350 |
72-79 |
NNS |
denotes |
effects |
| T2351 |
80-82 |
IN |
denotes |
of |
| T2352 |
83-96 |
NNS |
denotes |
neurotrophins |
| T2353 |
97-101 |
IN |
denotes |
from |
| T2354 |
102-107 |
JJ |
denotes |
other |
| T2355 |
108-115 |
NNS |
denotes |
effects |
| T2356 |
115-116 |
. |
denotes |
. |
| T2357 |
116-280 |
sentence |
denotes |
Bax-deficient sensory neurons no longer require neurotrophins for survival (White et al. 1998; Patel et al. 2000), thus they can be used to examine axonal effects. |
| T2358 |
117-120 |
NN |
denotes |
Bax |
| T2360 |
120-121 |
HYPH |
denotes |
- |
| T2359 |
121-130 |
JJ |
denotes |
deficient |
| T2362 |
131-138 |
JJ |
denotes |
sensory |
| T2361 |
139-146 |
NNS |
denotes |
neurons |
| T2364 |
147-149 |
RB |
denotes |
no |
| T2365 |
150-156 |
RB |
denotes |
longer |
| T2363 |
157-164 |
VBP |
denotes |
require |
| T2367 |
165-178 |
NNS |
denotes |
neurotrophins |
| T2368 |
179-182 |
IN |
denotes |
for |
| T2369 |
183-191 |
NN |
denotes |
survival |
| T2370 |
192-193 |
-LRB- |
denotes |
( |
| T2371 |
193-198 |
NNP |
denotes |
White |
| T2372 |
199-201 |
FW |
denotes |
et |
| T2373 |
202-205 |
FW |
denotes |
al. |
| T2374 |
206-210 |
CD |
denotes |
1998 |
| T2375 |
210-211 |
: |
denotes |
; |
| T2376 |
212-217 |
NNP |
denotes |
Patel |
| T2377 |
218-220 |
FW |
denotes |
et |
| T2378 |
221-224 |
FW |
denotes |
al. |
| T2379 |
225-229 |
CD |
denotes |
2000 |
| T2380 |
229-230 |
-RRB- |
denotes |
) |
| T2381 |
230-232 |
, |
denotes |
, |
| T2382 |
232-236 |
RB |
denotes |
thus |
| T2383 |
237-241 |
PRP |
denotes |
they |
| T2384 |
242-245 |
MD |
denotes |
can |
| T2385 |
246-248 |
VB |
denotes |
be |
| T2366 |
249-253 |
VBN |
denotes |
used |
| T2386 |
254-256 |
TO |
denotes |
to |
| T2387 |
257-264 |
VB |
denotes |
examine |
| T2388 |
265-271 |
JJ |
denotes |
axonal |
| T2389 |
272-279 |
NNS |
denotes |
effects |
| T2390 |
279-280 |
. |
denotes |
. |
| T2391 |
280-439 |
sentence |
denotes |
We bred NT-3 heterozygote and Bax knockout (KO) mice to obtain mice with double KO of both NT-3 and Bax genes, and examined proprioceptive axonal projections. |
| T2392 |
281-283 |
PRP |
denotes |
We |
| T2393 |
284-288 |
VBD |
denotes |
bred |
| T2394 |
289-291 |
NN |
denotes |
NT |
| T2396 |
291-292 |
HYPH |
denotes |
- |
| T2397 |
292-293 |
CD |
denotes |
3 |
| T2395 |
294-306 |
NN |
denotes |
heterozygote |
| T2398 |
307-310 |
CC |
denotes |
and |
| T2399 |
311-314 |
NN |
denotes |
Bax |
| T2400 |
315-323 |
NN |
denotes |
knockout |
| T2402 |
324-325 |
-LRB- |
denotes |
( |
| T2403 |
325-327 |
NN |
denotes |
KO |
| T2404 |
327-328 |
-RRB- |
denotes |
) |
| T2401 |
329-333 |
NNS |
denotes |
mice |
| T2405 |
334-336 |
TO |
denotes |
to |
| T2406 |
337-343 |
VB |
denotes |
obtain |
| T2407 |
344-348 |
NNS |
denotes |
mice |
| T2408 |
349-353 |
IN |
denotes |
with |
| T2409 |
354-360 |
JJ |
denotes |
double |
| T2410 |
361-363 |
NN |
denotes |
KO |
| T2411 |
364-366 |
IN |
denotes |
of |
| T2412 |
367-371 |
CC |
denotes |
both |
| T2413 |
372-374 |
NN |
denotes |
NT |
| T2415 |
374-375 |
HYPH |
denotes |
- |
| T2416 |
375-376 |
CD |
denotes |
3 |
| T2417 |
377-380 |
CC |
denotes |
and |
| T2418 |
381-384 |
NN |
denotes |
Bax |
| T2414 |
385-390 |
NNS |
denotes |
genes |
| T2419 |
390-392 |
, |
denotes |
, |
| T2420 |
392-395 |
CC |
denotes |
and |
| T2421 |
396-404 |
VBN |
denotes |
examined |
| T2422 |
405-419 |
JJ |
denotes |
proprioceptive |
| T2424 |
420-426 |
JJ |
denotes |
axonal |
| T2423 |
427-438 |
NNS |
denotes |
projections |
| T2425 |
438-439 |
. |
denotes |
. |
| T2426 |
439-518 |
sentence |
denotes |
All NT-3 and double KOs died within 48 h after birth (Tessarollo et al. 1994). |
| T2427 |
440-443 |
DT |
denotes |
All |
| T2429 |
444-446 |
NN |
denotes |
NT |
| T2430 |
446-447 |
HYPH |
denotes |
- |
| T2431 |
447-448 |
CD |
denotes |
3 |
| T2432 |
449-452 |
CC |
denotes |
and |
| T2433 |
453-459 |
JJ |
denotes |
double |
| T2428 |
460-463 |
NNS |
denotes |
KOs |
| T2434 |
464-468 |
VBD |
denotes |
died |
| T2435 |
469-475 |
IN |
denotes |
within |
| T2436 |
476-478 |
CD |
denotes |
48 |
| T2437 |
479-480 |
NN |
denotes |
h |
| T2438 |
481-486 |
IN |
denotes |
after |
| T2439 |
487-492 |
NN |
denotes |
birth |
| T2440 |
493-494 |
-LRB- |
denotes |
( |
| T2441 |
494-504 |
NNP |
denotes |
Tessarollo |
| T2442 |
505-507 |
FW |
denotes |
et |
| T2443 |
508-511 |
FW |
denotes |
al. |
| T2444 |
512-516 |
CD |
denotes |
1994 |
| T2445 |
516-517 |
-RRB- |
denotes |
) |
| T2446 |
517-518 |
. |
denotes |
. |
| T2447 |
518-646 |
sentence |
denotes |
We performed TrkA/TrkC double immunohistochemistry (Huang et al. 1999), enabling detection of both proteins in the same sample. |
| T2448 |
519-521 |
PRP |
denotes |
We |
| T2449 |
522-531 |
VBD |
denotes |
performed |
| T2450 |
532-536 |
NN |
denotes |
TrkA |
| T2452 |
536-537 |
HYPH |
denotes |
/ |
| T2451 |
537-541 |
NN |
denotes |
TrkC |
| T2454 |
542-548 |
JJ |
denotes |
double |
| T2453 |
549-569 |
NN |
denotes |
immunohistochemistry |
| T2455 |
570-571 |
-LRB- |
denotes |
( |
| T2456 |
571-576 |
NNP |
denotes |
Huang |
| T2457 |
577-579 |
FW |
denotes |
et |
| T2458 |
580-583 |
FW |
denotes |
al. |
| T2459 |
584-588 |
CD |
denotes |
1999 |
| T2460 |
588-589 |
-RRB- |
denotes |
) |
| T2461 |
589-591 |
, |
denotes |
, |
| T2462 |
591-599 |
VBG |
denotes |
enabling |
| T2463 |
600-609 |
NN |
denotes |
detection |
| T2464 |
610-612 |
IN |
denotes |
of |
| T2465 |
613-617 |
DT |
denotes |
both |
| T2466 |
618-626 |
NN |
denotes |
proteins |
| T2467 |
627-629 |
IN |
denotes |
in |
| T2468 |
630-633 |
DT |
denotes |
the |
| T2470 |
634-638 |
JJ |
denotes |
same |
| T2469 |
639-645 |
NN |
denotes |
sample |
| T2471 |
645-646 |
. |
denotes |
. |
| T2472 |
646-750 |
sentence |
denotes |
TrkC-positive cells (Figure 1A) and fibers (Figure 1E) were absent in NT-3 KOs at embryonic day (E) 15. |
| T2473 |
647-651 |
NN |
denotes |
TrkC |
| T2475 |
651-652 |
HYPH |
denotes |
- |
| T2474 |
652-660 |
JJ |
denotes |
positive |
| T2476 |
661-666 |
NNS |
denotes |
cells |
| T2478 |
667-668 |
-LRB- |
denotes |
( |
| T2480 |
668-674 |
NN |
denotes |
Figure |
| T2479 |
675-677 |
NN |
denotes |
1A |
| T2481 |
677-678 |
-RRB- |
denotes |
) |
| T2482 |
679-682 |
CC |
denotes |
and |
| T2483 |
683-689 |
NNS |
denotes |
fibers |
| T2484 |
690-691 |
-LRB- |
denotes |
( |
| T2486 |
691-697 |
NN |
denotes |
Figure |
| T2485 |
698-700 |
NN |
denotes |
1E |
| T2487 |
700-701 |
-RRB- |
denotes |
) |
| T2477 |
702-706 |
VBD |
denotes |
were |
| T2488 |
707-713 |
JJ |
denotes |
absent |
| T2489 |
714-716 |
IN |
denotes |
in |
| T2490 |
717-719 |
NN |
denotes |
NT |
| T2492 |
719-720 |
HYPH |
denotes |
- |
| T2493 |
720-721 |
CD |
denotes |
3 |
| T2491 |
722-725 |
NNS |
denotes |
KOs |
| T2494 |
726-728 |
IN |
denotes |
at |
| T2495 |
729-738 |
JJ |
denotes |
embryonic |
| T2496 |
739-742 |
NN |
denotes |
day |
| T2497 |
743-744 |
-LRB- |
denotes |
( |
| T2498 |
744-745 |
NN |
denotes |
E |
| T2499 |
745-746 |
-RRB- |
denotes |
) |
| T2500 |
747-749 |
CD |
denotes |
15 |
| T2501 |
749-750 |
. |
denotes |
. |
| T2502 |
750-880 |
sentence |
denotes |
Two subsets of DRG cells expressing either TrkA or TrkC were detected in double KOs, similar to wild-type (WT) or Bax KO animals. |
| T2503 |
751-754 |
CD |
denotes |
Two |
| T2504 |
755-762 |
NNS |
denotes |
subsets |
| T2506 |
763-765 |
IN |
denotes |
of |
| T2507 |
766-769 |
NN |
denotes |
DRG |
| T2508 |
770-775 |
NNS |
denotes |
cells |
| T2509 |
776-786 |
VBG |
denotes |
expressing |
| T2510 |
787-793 |
CC |
denotes |
either |
| T2511 |
794-798 |
NN |
denotes |
TrkA |
| T2512 |
799-801 |
CC |
denotes |
or |
| T2513 |
802-806 |
NN |
denotes |
TrkC |
| T2514 |
807-811 |
VBD |
denotes |
were |
| T2505 |
812-820 |
VBN |
denotes |
detected |
| T2515 |
821-823 |
IN |
denotes |
in |
| T2516 |
824-830 |
JJ |
denotes |
double |
| T2517 |
831-834 |
NNS |
denotes |
KOs |
| T2518 |
834-836 |
, |
denotes |
, |
| T2519 |
836-843 |
JJ |
denotes |
similar |
| T2520 |
844-846 |
IN |
denotes |
to |
| T2521 |
847-851 |
JJ |
denotes |
wild |
| T2523 |
851-852 |
HYPH |
denotes |
- |
| T2522 |
852-856 |
NN |
denotes |
type |
| T2525 |
857-858 |
-LRB- |
denotes |
( |
| T2526 |
858-860 |
NN |
denotes |
WT |
| T2527 |
860-861 |
-RRB- |
denotes |
) |
| T2528 |
862-864 |
CC |
denotes |
or |
| T2529 |
865-868 |
NN |
denotes |
Bax |
| T2530 |
869-871 |
NN |
denotes |
KO |
| T2524 |
872-879 |
NNS |
denotes |
animals |
| T2531 |
879-880 |
. |
denotes |
. |
| T2532 |
880-1087 |
sentence |
denotes |
Surprisingly, at postnatal day (P) 0, a few cells expressed TrkC even in NT-3 KO animals in the Bax +/+ genetic background, and some cells co-expressed TrkA and TrkC, regardless of the genotype (Figure 1B). |
| T2533 |
881-893 |
RB |
denotes |
Surprisingly |
| T2535 |
893-895 |
, |
denotes |
, |
| T2536 |
895-897 |
IN |
denotes |
at |
| T2537 |
898-907 |
JJ |
denotes |
postnatal |
| T2538 |
908-911 |
NN |
denotes |
day |
| T2539 |
912-913 |
-LRB- |
denotes |
( |
| T2540 |
913-914 |
NN |
denotes |
P |
| T2541 |
914-915 |
-RRB- |
denotes |
) |
| T2542 |
916-917 |
CD |
denotes |
0 |
| T2543 |
917-919 |
, |
denotes |
, |
| T2544 |
919-920 |
DT |
denotes |
a |
| T2546 |
921-924 |
JJ |
denotes |
few |
| T2545 |
925-930 |
NNS |
denotes |
cells |
| T2534 |
931-940 |
VBD |
denotes |
expressed |
| T2547 |
941-945 |
NN |
denotes |
TrkC |
| T2548 |
946-950 |
RB |
denotes |
even |
| T2549 |
951-953 |
IN |
denotes |
in |
| T2550 |
954-956 |
NN |
denotes |
NT |
| T2552 |
956-957 |
HYPH |
denotes |
- |
| T2553 |
957-958 |
CD |
denotes |
3 |
| T2551 |
959-961 |
NN |
denotes |
KO |
| T2554 |
962-969 |
NNS |
denotes |
animals |
| T2555 |
970-972 |
IN |
denotes |
in |
| T2556 |
973-976 |
DT |
denotes |
the |
| T2558 |
977-980 |
NN |
denotes |
Bax |
| T2559 |
981-982 |
SYM |
denotes |
+ |
| T2560 |
982-983 |
HYPH |
denotes |
/ |
| T2561 |
983-984 |
SYM |
denotes |
+ |
| T2562 |
985-992 |
JJ |
denotes |
genetic |
| T2557 |
993-1003 |
NN |
denotes |
background |
| T2563 |
1003-1005 |
, |
denotes |
, |
| T2564 |
1005-1008 |
CC |
denotes |
and |
| T2565 |
1009-1013 |
DT |
denotes |
some |
| T2566 |
1014-1019 |
NNS |
denotes |
cells |
| T2567 |
1020-1032 |
VBD |
denotes |
co-expressed |
| T2568 |
1033-1037 |
NN |
denotes |
TrkA |
| T2569 |
1038-1041 |
CC |
denotes |
and |
| T2570 |
1042-1046 |
NN |
denotes |
TrkC |
| T2571 |
1046-1048 |
, |
denotes |
, |
| T2572 |
1048-1058 |
RB |
denotes |
regardless |
| T2573 |
1059-1061 |
IN |
denotes |
of |
| T2574 |
1062-1065 |
DT |
denotes |
the |
| T2575 |
1066-1074 |
NN |
denotes |
genotype |
| T2576 |
1075-1076 |
-LRB- |
denotes |
( |
| T2578 |
1076-1082 |
NN |
denotes |
Figure |
| T2577 |
1083-1085 |
NN |
denotes |
1B |
| T2579 |
1085-1086 |
-RRB- |
denotes |
) |
| T2580 |
1086-1087 |
. |
denotes |
. |
| T2581 |
1087-1241 |
sentence |
denotes |
In order to quantify our results, we analyzed the ratio of TrkA and TrkC immunopositive cells from four different DRGs of animals of different genotypes. |
| T2582 |
1088-1090 |
IN |
denotes |
In |
| T2584 |
1091-1096 |
NN |
denotes |
order |
| T2585 |
1097-1099 |
TO |
denotes |
to |
| T2586 |
1100-1108 |
VB |
denotes |
quantify |
| T2587 |
1109-1112 |
PRP$ |
denotes |
our |
| T2588 |
1113-1120 |
NNS |
denotes |
results |
| T2589 |
1120-1122 |
, |
denotes |
, |
| T2590 |
1122-1124 |
PRP |
denotes |
we |
| T2583 |
1125-1133 |
VBD |
denotes |
analyzed |
| T2591 |
1134-1137 |
DT |
denotes |
the |
| T2592 |
1138-1143 |
NN |
denotes |
ratio |
| T2593 |
1144-1146 |
IN |
denotes |
of |
| T2594 |
1147-1151 |
NN |
denotes |
TrkA |
| T2596 |
1152-1155 |
CC |
denotes |
and |
| T2597 |
1156-1160 |
NN |
denotes |
TrkC |
| T2595 |
1161-1175 |
JJ |
denotes |
immunopositive |
| T2598 |
1176-1181 |
NNS |
denotes |
cells |
| T2599 |
1182-1186 |
IN |
denotes |
from |
| T2600 |
1187-1191 |
CD |
denotes |
four |
| T2602 |
1192-1201 |
JJ |
denotes |
different |
| T2601 |
1202-1206 |
NNS |
denotes |
DRGs |
| T2603 |
1207-1209 |
IN |
denotes |
of |
| T2604 |
1210-1217 |
NNS |
denotes |
animals |
| T2605 |
1218-1220 |
IN |
denotes |
of |
| T2606 |
1221-1230 |
JJ |
denotes |
different |
| T2607 |
1231-1240 |
NNS |
denotes |
genotypes |
| T2608 |
1240-1241 |
. |
denotes |
. |
| T2609 |
1241-1397 |
sentence |
denotes |
At all ages studied, Bax/NT-3 double null DRGs had TrkA/TrkC ratios similar to those of Bax null DRGs, and higher than those of NT-3 null DRGs (Figure 1D). |
| T2610 |
1242-1244 |
IN |
denotes |
At |
| T2612 |
1245-1248 |
DT |
denotes |
all |
| T2613 |
1249-1253 |
NNS |
denotes |
ages |
| T2614 |
1254-1261 |
VBN |
denotes |
studied |
| T2615 |
1261-1263 |
, |
denotes |
, |
| T2616 |
1263-1266 |
NN |
denotes |
Bax |
| T2618 |
1266-1267 |
HYPH |
denotes |
/ |
| T2619 |
1267-1269 |
NN |
denotes |
NT |
| T2620 |
1269-1270 |
HYPH |
denotes |
- |
| T2621 |
1270-1271 |
CD |
denotes |
3 |
| T2622 |
1272-1278 |
JJ |
denotes |
double |
| T2617 |
1279-1283 |
JJ |
denotes |
null |
| T2623 |
1284-1288 |
NNS |
denotes |
DRGs |
| T2611 |
1289-1292 |
VBD |
denotes |
had |
| T2624 |
1293-1297 |
NN |
denotes |
TrkA |
| T2626 |
1297-1298 |
HYPH |
denotes |
/ |
| T2625 |
1298-1302 |
NN |
denotes |
TrkC |
| T2627 |
1303-1309 |
NNS |
denotes |
ratios |
| T2628 |
1310-1317 |
JJ |
denotes |
similar |
| T2629 |
1318-1320 |
IN |
denotes |
to |
| T2630 |
1321-1326 |
DT |
denotes |
those |
| T2631 |
1327-1329 |
IN |
denotes |
of |
| T2632 |
1330-1333 |
NN |
denotes |
Bax |
| T2633 |
1334-1338 |
JJ |
denotes |
null |
| T2634 |
1339-1343 |
NNS |
denotes |
DRGs |
| T2635 |
1343-1345 |
, |
denotes |
, |
| T2636 |
1345-1348 |
CC |
denotes |
and |
| T2637 |
1349-1355 |
JJR |
denotes |
higher |
| T2638 |
1356-1360 |
IN |
denotes |
than |
| T2639 |
1361-1366 |
DT |
denotes |
those |
| T2640 |
1367-1369 |
IN |
denotes |
of |
| T2641 |
1370-1372 |
NN |
denotes |
NT |
| T2643 |
1372-1373 |
HYPH |
denotes |
- |
| T2644 |
1373-1374 |
CD |
denotes |
3 |
| T2642 |
1375-1379 |
JJ |
denotes |
null |
| T2645 |
1380-1384 |
NNS |
denotes |
DRGs |
| T2646 |
1385-1386 |
-LRB- |
denotes |
( |
| T2648 |
1386-1392 |
NN |
denotes |
Figure |
| T2647 |
1393-1395 |
NN |
denotes |
1D |
| T2649 |
1395-1396 |
-RRB- |
denotes |
) |
| T2650 |
1396-1397 |
. |
denotes |
. |
| T2651 |
1397-1595 |
sentence |
denotes |
TrkC-positive neurons rescued by Bax deletion, however, failed to differentiate properly, as evidenced by the lack of expression of the proprioceptive molecular marker Parvalbumin (PV) (Figure 1C). |
| T2652 |
1398-1402 |
NN |
denotes |
TrkC |
| T2654 |
1402-1403 |
HYPH |
denotes |
- |
| T2653 |
1403-1411 |
JJ |
denotes |
positive |
| T2655 |
1412-1419 |
NNS |
denotes |
neurons |
| T2657 |
1420-1427 |
VBN |
denotes |
rescued |
| T2658 |
1428-1430 |
IN |
denotes |
by |
| T2659 |
1431-1434 |
NN |
denotes |
Bax |
| T2660 |
1435-1443 |
NN |
denotes |
deletion |
| T2661 |
1443-1445 |
, |
denotes |
, |
| T2662 |
1445-1452 |
RB |
denotes |
however |
| T2663 |
1452-1454 |
, |
denotes |
, |
| T2656 |
1454-1460 |
VBD |
denotes |
failed |
| T2664 |
1461-1463 |
TO |
denotes |
to |
| T2665 |
1464-1477 |
VB |
denotes |
differentiate |
| T2666 |
1478-1486 |
RB |
denotes |
properly |
| T2667 |
1486-1488 |
, |
denotes |
, |
| T2668 |
1488-1490 |
IN |
denotes |
as |
| T2669 |
1491-1500 |
VBN |
denotes |
evidenced |
| T2670 |
1501-1503 |
IN |
denotes |
by |
| T2671 |
1504-1507 |
DT |
denotes |
the |
| T2672 |
1508-1512 |
NN |
denotes |
lack |
| T2673 |
1513-1515 |
IN |
denotes |
of |
| T2674 |
1516-1526 |
NN |
denotes |
expression |
| T2675 |
1527-1529 |
IN |
denotes |
of |
| T2676 |
1530-1533 |
DT |
denotes |
the |
| T2678 |
1534-1548 |
JJ |
denotes |
proprioceptive |
| T2679 |
1549-1558 |
JJ |
denotes |
molecular |
| T2677 |
1559-1565 |
NN |
denotes |
marker |
| T2680 |
1566-1577 |
NN |
denotes |
Parvalbumin |
| T2681 |
1578-1579 |
-LRB- |
denotes |
( |
| T2682 |
1579-1581 |
NN |
denotes |
PV |
| T2683 |
1581-1582 |
-RRB- |
denotes |
) |
| T2684 |
1583-1584 |
-LRB- |
denotes |
( |
| T2686 |
1584-1590 |
NN |
denotes |
Figure |
| T2685 |
1591-1593 |
NN |
denotes |
1C |
| T2687 |
1593-1594 |
-RRB- |
denotes |
) |
| T2688 |
1594-1595 |
. |
denotes |
. |
| R459 |
T2341 |
T2342 |
nsubj |
Mice,allow |
| R460 |
T2343 |
T2341 |
acl |
lacking,Mice |
| R461 |
T2344 |
T2345 |
amod |
proapoptotic,Bax |
| R462 |
T2345 |
T2343 |
dobj |
Bax,lacking |
| R463 |
T2346 |
T2345 |
compound |
protein,Bax |
| R464 |
T2347 |
T2342 |
prep |
for,allow |
| R465 |
T2348 |
T2347 |
pcomp |
distinguishing,for |
| R466 |
T2349 |
T2350 |
compound |
survival,effects |
| R467 |
T2350 |
T2348 |
dobj |
effects,distinguishing |
| R468 |
T2351 |
T2350 |
prep |
of,effects |
| R469 |
T2352 |
T2351 |
pobj |
neurotrophins,of |
| R470 |
T2353 |
T2348 |
prep |
from,distinguishing |
| R471 |
T2354 |
T2355 |
amod |
other,effects |
| R472 |
T2355 |
T2353 |
pobj |
effects,from |
| R473 |
T2356 |
T2342 |
punct |
.,allow |
| R474 |
T2358 |
T2359 |
npadvmod |
Bax,deficient |
| R475 |
T2359 |
T2361 |
amod |
deficient,neurons |
| R476 |
T2360 |
T2359 |
punct |
-,deficient |
| R477 |
T2361 |
T2363 |
nsubj |
neurons,require |
| R478 |
T2362 |
T2361 |
amod |
sensory,neurons |
| R479 |
T2363 |
T2366 |
ccomp |
require,used |
| R480 |
T2364 |
T2365 |
neg |
no,longer |
| R481 |
T2365 |
T2363 |
advmod |
longer,require |
| R482 |
T2367 |
T2363 |
dobj |
neurotrophins,require |
| R483 |
T2368 |
T2363 |
prep |
for,require |
| R484 |
T2369 |
T2368 |
pobj |
survival,for |
| R485 |
T2370 |
T2371 |
punct |
(,White |
| R486 |
T2371 |
T2363 |
meta |
White,require |
| R487 |
T2372 |
T2371 |
nmod |
et,White |
| R488 |
T2373 |
T2371 |
nmod |
al.,White |
| R489 |
T2374 |
T2371 |
nummod |
1998,White |
| R490 |
T2375 |
T2371 |
punct |
;,White |
| R491 |
T2376 |
T2371 |
nmod |
Patel,White |
| R492 |
T2377 |
T2371 |
nmod |
et,White |
| R493 |
T2378 |
T2371 |
nmod |
al.,White |
| R494 |
T2379 |
T2371 |
nummod |
2000,White |
| R495 |
T2380 |
T2371 |
punct |
),White |
| R496 |
T2381 |
T2366 |
punct |
", ",used |
| R497 |
T2382 |
T2366 |
advmod |
thus,used |
| R498 |
T2383 |
T2366 |
nsubjpass |
they,used |
| R499 |
T2384 |
T2366 |
aux |
can,used |
| R500 |
T2385 |
T2366 |
auxpass |
be,used |
| R501 |
T2386 |
T2387 |
aux |
to,examine |
| R502 |
T2387 |
T2366 |
advcl |
examine,used |
| R503 |
T2388 |
T2389 |
amod |
axonal,effects |
| R504 |
T2389 |
T2387 |
dobj |
effects,examine |
| R505 |
T2390 |
T2366 |
punct |
.,used |
| R506 |
T2392 |
T2393 |
nsubj |
We,bred |
| R507 |
T2394 |
T2395 |
nmod |
NT,heterozygote |
| R508 |
T2395 |
T2393 |
dobj |
heterozygote,bred |
| R509 |
T2396 |
T2394 |
punct |
-,NT |
| R510 |
T2397 |
T2394 |
nummod |
3,NT |
| R511 |
T2398 |
T2395 |
cc |
and,heterozygote |
| R512 |
T2399 |
T2400 |
nmod |
Bax,knockout |
| R513 |
T2400 |
T2401 |
nmod |
knockout,mice |
| R514 |
T2401 |
T2395 |
conj |
mice,heterozygote |
| R515 |
T2402 |
T2400 |
punct |
(,knockout |
| R516 |
T2403 |
T2400 |
appos |
KO,knockout |
| R517 |
T2404 |
T2401 |
punct |
),mice |
| R518 |
T2405 |
T2406 |
aux |
to,obtain |
| R519 |
T2406 |
T2393 |
advcl |
obtain,bred |
| R520 |
T2407 |
T2406 |
dobj |
mice,obtain |
| R521 |
T2408 |
T2407 |
prep |
with,mice |
| R522 |
T2409 |
T2410 |
amod |
double,KO |
| R523 |
T2410 |
T2408 |
pobj |
KO,with |
| R524 |
T2411 |
T2410 |
prep |
of,KO |
| R525 |
T2412 |
T2413 |
preconj |
both,NT |
| R526 |
T2413 |
T2414 |
nmod |
NT,genes |
| R527 |
T2414 |
T2411 |
pobj |
genes,of |
| R528 |
T2415 |
T2413 |
punct |
-,NT |
| R529 |
T2416 |
T2413 |
nummod |
3,NT |
| R530 |
T2417 |
T2413 |
cc |
and,NT |
| R531 |
T2418 |
T2413 |
conj |
Bax,NT |
| R532 |
T2419 |
T2393 |
punct |
", ",bred |
| R533 |
T2420 |
T2393 |
cc |
and,bred |
| R534 |
T2421 |
T2393 |
conj |
examined,bred |
| R535 |
T2422 |
T2423 |
amod |
proprioceptive,projections |
| R536 |
T2423 |
T2421 |
dobj |
projections,examined |
| R537 |
T2424 |
T2423 |
amod |
axonal,projections |
| R538 |
T2425 |
T2393 |
punct |
.,bred |
| R539 |
T2427 |
T2428 |
det |
All,KOs |
| R540 |
T2428 |
T2434 |
nsubj |
KOs,died |
| R541 |
T2429 |
T2428 |
nmod |
NT,KOs |
| R542 |
T2430 |
T2429 |
punct |
-,NT |
| R543 |
T2431 |
T2429 |
nummod |
3,NT |
| R544 |
T2432 |
T2429 |
cc |
and,NT |
| R545 |
T2433 |
T2429 |
conj |
double,NT |
| R546 |
T2435 |
T2434 |
prep |
within,died |
| R547 |
T2436 |
T2437 |
nummod |
48,h |
| R548 |
T2437 |
T2435 |
pobj |
h,within |
| R549 |
T2438 |
T2437 |
prep |
after,h |
| R550 |
T2439 |
T2438 |
pobj |
birth,after |
| R551 |
T2440 |
T2441 |
punct |
(,Tessarollo |
| R552 |
T2441 |
T2434 |
meta |
Tessarollo,died |
| R553 |
T2442 |
T2441 |
nmod |
et,Tessarollo |
| R554 |
T2443 |
T2441 |
nmod |
al.,Tessarollo |
| R555 |
T2444 |
T2441 |
nummod |
1994,Tessarollo |
| R556 |
T2445 |
T2441 |
punct |
),Tessarollo |
| R557 |
T2446 |
T2434 |
punct |
.,died |
| R558 |
T2448 |
T2449 |
nsubj |
We,performed |
| R559 |
T2450 |
T2451 |
nmod |
TrkA,TrkC |
| R560 |
T2451 |
T2453 |
nmod |
TrkC,immunohistochemistry |
| R561 |
T2452 |
T2451 |
punct |
/,TrkC |
| R562 |
T2453 |
T2449 |
dobj |
immunohistochemistry,performed |
| R563 |
T2454 |
T2453 |
amod |
double,immunohistochemistry |
| R564 |
T2455 |
T2456 |
punct |
(,Huang |
| R565 |
T2456 |
T2453 |
meta |
Huang,immunohistochemistry |
| R566 |
T2457 |
T2456 |
nmod |
et,Huang |
| R567 |
T2458 |
T2456 |
nmod |
al.,Huang |
| R568 |
T2459 |
T2456 |
nummod |
1999,Huang |
| R569 |
T2460 |
T2456 |
punct |
),Huang |
| R570 |
T2461 |
T2449 |
punct |
", ",performed |
| R571 |
T2462 |
T2449 |
advcl |
enabling,performed |
| R572 |
T2463 |
T2462 |
dobj |
detection,enabling |
| R573 |
T2464 |
T2463 |
prep |
of,detection |
| R574 |
T2465 |
T2466 |
det |
both,proteins |
| R575 |
T2466 |
T2464 |
pobj |
proteins,of |
| R576 |
T2467 |
T2462 |
prep |
in,enabling |
| R577 |
T2468 |
T2469 |
det |
the,sample |
| R578 |
T2469 |
T2467 |
pobj |
sample,in |
| R579 |
T2470 |
T2469 |
amod |
same,sample |
| R580 |
T2471 |
T2449 |
punct |
.,performed |
| R581 |
T2473 |
T2474 |
npadvmod |
TrkC,positive |
| R582 |
T2474 |
T2476 |
amod |
positive,cells |
| R583 |
T2475 |
T2474 |
punct |
-,positive |
| R584 |
T2476 |
T2477 |
nsubj |
cells,were |
| R585 |
T2478 |
T2479 |
punct |
(,1A |
| R586 |
T2479 |
T2476 |
parataxis |
1A,cells |
| R587 |
T2480 |
T2479 |
compound |
Figure,1A |
| R588 |
T2481 |
T2479 |
punct |
),1A |
| R589 |
T2482 |
T2476 |
cc |
and,cells |
| R590 |
T2483 |
T2476 |
conj |
fibers,cells |
| R591 |
T2484 |
T2485 |
punct |
(,1E |
| R592 |
T2485 |
T2483 |
parataxis |
1E,fibers |
| R593 |
T2486 |
T2485 |
compound |
Figure,1E |
| R594 |
T2487 |
T2485 |
punct |
),1E |
| R595 |
T2488 |
T2477 |
acomp |
absent,were |
| R596 |
T2489 |
T2477 |
prep |
in,were |
| R597 |
T2490 |
T2491 |
nmod |
NT,KOs |
| R598 |
T2491 |
T2489 |
pobj |
KOs,in |
| R599 |
T2492 |
T2490 |
punct |
-,NT |
| R600 |
T2493 |
T2490 |
nummod |
3,NT |
| R601 |
T2494 |
T2477 |
prep |
at,were |
| R602 |
T2495 |
T2496 |
amod |
embryonic,day |
| R603 |
T2496 |
T2494 |
pobj |
day,at |
| R604 |
T2497 |
T2496 |
punct |
(,day |
| R605 |
T2498 |
T2496 |
appos |
E,day |
| R606 |
T2499 |
T2496 |
punct |
),day |
| R607 |
T2500 |
T2496 |
nummod |
15,day |
| R608 |
T2501 |
T2477 |
punct |
.,were |
| R609 |
T2503 |
T2504 |
nummod |
Two,subsets |
| R610 |
T2504 |
T2505 |
nsubjpass |
subsets,detected |
| R611 |
T2506 |
T2504 |
prep |
of,subsets |
| R612 |
T2507 |
T2508 |
compound |
DRG,cells |
| R613 |
T2508 |
T2506 |
pobj |
cells,of |
| R614 |
T2509 |
T2504 |
acl |
expressing,subsets |
| R615 |
T2510 |
T2511 |
preconj |
either,TrkA |
| R616 |
T2511 |
T2509 |
dobj |
TrkA,expressing |
| R617 |
T2512 |
T2511 |
cc |
or,TrkA |
| R618 |
T2513 |
T2511 |
conj |
TrkC,TrkA |
| R619 |
T2514 |
T2505 |
auxpass |
were,detected |
| R620 |
T2515 |
T2505 |
prep |
in,detected |
| R621 |
T2516 |
T2517 |
amod |
double,KOs |
| R622 |
T2517 |
T2515 |
pobj |
KOs,in |
| R623 |
T2518 |
T2505 |
punct |
", ",detected |
| R624 |
T2519 |
T2505 |
advcl |
similar,detected |
| R625 |
T2520 |
T2519 |
prep |
to,similar |
| R626 |
T2521 |
T2522 |
amod |
wild,type |
| R627 |
T2522 |
T2524 |
nmod |
type,animals |
| R628 |
T2523 |
T2522 |
punct |
-,type |
| R629 |
T2524 |
T2520 |
pobj |
animals,to |
| R630 |
T2525 |
T2522 |
punct |
(,type |
| R631 |
T2526 |
T2522 |
appos |
WT,type |
| R632 |
T2527 |
T2522 |
punct |
),type |
| R633 |
T2528 |
T2522 |
cc |
or,type |
| R634 |
T2529 |
T2530 |
compound |
Bax,KO |
| R635 |
T2530 |
T2522 |
conj |
KO,type |
| R636 |
T2531 |
T2505 |
punct |
.,detected |
| R637 |
T2533 |
T2534 |
advmod |
Surprisingly,expressed |
| R638 |
T2535 |
T2534 |
punct |
", ",expressed |
| R639 |
T2536 |
T2534 |
prep |
at,expressed |
| R640 |
T2537 |
T2538 |
amod |
postnatal,day |
| R641 |
T2538 |
T2536 |
pobj |
day,at |
| R642 |
T2539 |
T2538 |
punct |
(,day |
| R643 |
T2540 |
T2538 |
appos |
P,day |
| R644 |
T2541 |
T2538 |
punct |
),day |
| R645 |
T2542 |
T2538 |
nummod |
0,day |
| R646 |
T2543 |
T2534 |
punct |
", ",expressed |
| R647 |
T2544 |
T2545 |
det |
a,cells |
| R648 |
T2545 |
T2534 |
nsubj |
cells,expressed |
| R649 |
T2546 |
T2545 |
amod |
few,cells |
| R650 |
T2547 |
T2534 |
dobj |
TrkC,expressed |
| R651 |
T2548 |
T2549 |
advmod |
even,in |
| R652 |
T2549 |
T2534 |
prep |
in,expressed |
| R653 |
T2550 |
T2551 |
nmod |
NT,KO |
| R654 |
T2551 |
T2554 |
compound |
KO,animals |
| R655 |
T2552 |
T2550 |
punct |
-,NT |
| R656 |
T2553 |
T2550 |
nummod |
3,NT |
| R657 |
T2554 |
T2549 |
pobj |
animals,in |
| R658 |
T2555 |
T2554 |
prep |
in,animals |
| R659 |
T2556 |
T2557 |
det |
the,background |
| R660 |
T2557 |
T2555 |
pobj |
background,in |
| R661 |
T2558 |
T2557 |
nmod |
Bax,background |
| R662 |
T2559 |
T2558 |
punct |
+,Bax |
| R663 |
T2560 |
T2558 |
punct |
/,Bax |
| R664 |
T2561 |
T2558 |
punct |
+,Bax |
| R665 |
T2562 |
T2557 |
amod |
genetic,background |
| R666 |
T2563 |
T2534 |
punct |
", ",expressed |
| R667 |
T2564 |
T2534 |
cc |
and,expressed |
| R668 |
T2565 |
T2566 |
det |
some,cells |
| R669 |
T2566 |
T2567 |
nsubj |
cells,co-expressed |
| R670 |
T2567 |
T2534 |
conj |
co-expressed,expressed |
| R671 |
T2568 |
T2567 |
dobj |
TrkA,co-expressed |
| R672 |
T2569 |
T2568 |
cc |
and,TrkA |
| R673 |
T2570 |
T2568 |
conj |
TrkC,TrkA |
| R674 |
T2571 |
T2567 |
punct |
", ",co-expressed |
| R675 |
T2572 |
T2567 |
advmod |
regardless,co-expressed |
| R676 |
T2573 |
T2572 |
prep |
of,regardless |
| R677 |
T2574 |
T2575 |
det |
the,genotype |
| R678 |
T2575 |
T2573 |
pobj |
genotype,of |
| R679 |
T2576 |
T2577 |
punct |
(,1B |
| R680 |
T2577 |
T2567 |
parataxis |
1B,co-expressed |
| R681 |
T2578 |
T2577 |
compound |
Figure,1B |
| R682 |
T2579 |
T2577 |
punct |
),1B |
| R683 |
T2580 |
T2534 |
punct |
.,expressed |
| R684 |
T2582 |
T2583 |
prep |
In,analyzed |
| R685 |
T2584 |
T2582 |
pobj |
order,In |
| R686 |
T2585 |
T2586 |
aux |
to,quantify |
| R687 |
T2586 |
T2584 |
acl |
quantify,order |
| R688 |
T2587 |
T2588 |
poss |
our,results |
| R689 |
T2588 |
T2586 |
dobj |
results,quantify |
| R690 |
T2589 |
T2583 |
punct |
", ",analyzed |
| R691 |
T2590 |
T2583 |
nsubj |
we,analyzed |
| R692 |
T2591 |
T2592 |
det |
the,ratio |
| R693 |
T2592 |
T2583 |
dobj |
ratio,analyzed |
| R694 |
T2593 |
T2592 |
prep |
of,ratio |
| R695 |
T2594 |
T2595 |
npadvmod |
TrkA,immunopositive |
| R696 |
T2595 |
T2598 |
amod |
immunopositive,cells |
| R697 |
T2596 |
T2594 |
cc |
and,TrkA |
| R698 |
T2597 |
T2594 |
conj |
TrkC,TrkA |
| R699 |
T2598 |
T2593 |
pobj |
cells,of |
| R700 |
T2599 |
T2598 |
prep |
from,cells |
| R701 |
T2600 |
T2601 |
nummod |
four,DRGs |
| R702 |
T2601 |
T2599 |
pobj |
DRGs,from |
| R703 |
T2602 |
T2601 |
amod |
different,DRGs |
| R704 |
T2603 |
T2601 |
prep |
of,DRGs |
| R705 |
T2604 |
T2603 |
pobj |
animals,of |
| R706 |
T2605 |
T2604 |
prep |
of,animals |
| R707 |
T2606 |
T2607 |
amod |
different,genotypes |
| R708 |
T2607 |
T2605 |
pobj |
genotypes,of |
| R709 |
T2608 |
T2583 |
punct |
.,analyzed |
| R710 |
T2610 |
T2611 |
prep |
At,had |
| R711 |
T2612 |
T2613 |
det |
all,ages |
| R712 |
T2613 |
T2610 |
pobj |
ages,At |
| R713 |
T2614 |
T2613 |
acl |
studied,ages |
| R714 |
T2615 |
T2611 |
punct |
", ",had |
| R715 |
T2616 |
T2617 |
npadvmod |
Bax,null |
| R716 |
T2617 |
T2623 |
amod |
null,DRGs |
| R717 |
T2618 |
T2616 |
punct |
/,Bax |
| R718 |
T2619 |
T2616 |
appos |
NT,Bax |
| R719 |
T2620 |
T2619 |
punct |
-,NT |
| R720 |
T2621 |
T2619 |
nummod |
3,NT |
| R721 |
T2622 |
T2617 |
amod |
double,null |
| R722 |
T2623 |
T2611 |
nsubj |
DRGs,had |
| R723 |
T2624 |
T2625 |
compound |
TrkA,TrkC |
| R724 |
T2625 |
T2627 |
compound |
TrkC,ratios |
| R725 |
T2626 |
T2625 |
punct |
/,TrkC |
| R726 |
T2627 |
T2611 |
dobj |
ratios,had |
| R727 |
T2628 |
T2627 |
amod |
similar,ratios |
| R728 |
T2629 |
T2628 |
prep |
to,similar |
| R729 |
T2630 |
T2629 |
pobj |
those,to |
| R730 |
T2631 |
T2630 |
prep |
of,those |
| R731 |
T2632 |
T2633 |
npadvmod |
Bax,null |
| R732 |
T2633 |
T2634 |
amod |
null,DRGs |
| R733 |
T2634 |
T2631 |
pobj |
DRGs,of |
| R734 |
T2635 |
T2628 |
punct |
", ",similar |
| R735 |
T2636 |
T2628 |
cc |
and,similar |
| R736 |
T2637 |
T2628 |
conj |
higher,similar |
| R737 |
T2638 |
T2637 |
prep |
than,higher |
| R738 |
T2639 |
T2638 |
pobj |
those,than |
| R739 |
T2640 |
T2639 |
prep |
of,those |
| R740 |
T2641 |
T2642 |
npadvmod |
NT,null |
| R741 |
T2642 |
T2645 |
amod |
null,DRGs |
| R742 |
T2643 |
T2641 |
punct |
-,NT |
| R743 |
T2644 |
T2641 |
nummod |
3,NT |
| R744 |
T2645 |
T2640 |
pobj |
DRGs,of |
| R745 |
T2646 |
T2647 |
punct |
(,1D |
| R746 |
T2647 |
T2611 |
parataxis |
1D,had |
| R747 |
T2648 |
T2647 |
compound |
Figure,1D |
| R748 |
T2649 |
T2647 |
punct |
),1D |
| R749 |
T2650 |
T2611 |
punct |
.,had |
| R750 |
T2652 |
T2653 |
npadvmod |
TrkC,positive |
| R751 |
T2653 |
T2655 |
amod |
positive,neurons |
| R752 |
T2654 |
T2653 |
punct |
-,positive |
| R753 |
T2655 |
T2656 |
nsubj |
neurons,failed |
| R754 |
T2657 |
T2655 |
acl |
rescued,neurons |
| R755 |
T2658 |
T2657 |
prep |
by,rescued |
| R756 |
T2659 |
T2660 |
compound |
Bax,deletion |
| R757 |
T2660 |
T2658 |
pobj |
deletion,by |
| R758 |
T2661 |
T2656 |
punct |
", ",failed |
| R759 |
T2662 |
T2656 |
advmod |
however,failed |
| R760 |
T2663 |
T2656 |
punct |
", ",failed |
| R761 |
T2664 |
T2665 |
aux |
to,differentiate |
| R762 |
T2665 |
T2656 |
xcomp |
differentiate,failed |
| R763 |
T2666 |
T2665 |
advmod |
properly,differentiate |
| R764 |
T2667 |
T2665 |
punct |
", ",differentiate |
| R765 |
T2668 |
T2669 |
mark |
as,evidenced |
| R766 |
T2669 |
T2665 |
advcl |
evidenced,differentiate |
| R767 |
T2670 |
T2669 |
prep |
by,evidenced |
| R768 |
T2671 |
T2672 |
det |
the,lack |
| R769 |
T2672 |
T2670 |
pobj |
lack,by |
| R770 |
T2673 |
T2672 |
prep |
of,lack |
| R771 |
T2674 |
T2673 |
pobj |
expression,of |
| R772 |
T2675 |
T2674 |
prep |
of,expression |
| R773 |
T2676 |
T2677 |
det |
the,marker |
| R774 |
T2677 |
T2675 |
pobj |
marker,of |
| R775 |
T2678 |
T2677 |
amod |
proprioceptive,marker |
| R776 |
T2679 |
T2677 |
amod |
molecular,marker |
| R777 |
T2680 |
T2677 |
appos |
Parvalbumin,marker |
| R778 |
T2681 |
T2677 |
punct |
(,marker |
| R779 |
T2682 |
T2677 |
appos |
PV,marker |
| R780 |
T2683 |
T2656 |
punct |
),failed |
| R781 |
T2684 |
T2685 |
punct |
(,1C |
| R782 |
T2685 |
T2656 |
parataxis |
1C,failed |
| R783 |
T2686 |
T2685 |
compound |
Figure,1C |
| R784 |
T2687 |
T2685 |
punct |
),1C |
| R785 |
T2688 |
T2656 |
punct |
.,failed |
