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PMC:529315 / 112-965 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T425 12-13 HYPH denotes -
T426 13-14 CD denotes 3
T427 15-16 -LRB- denotes (
T428 16-18 NN denotes NT
T429 18-19 HYPH denotes -
T430 19-20 CD denotes 3
T431 20-21 -RRB- denotes )
T432 22-24 VBZ denotes is
T424 25-33 VBN denotes required
T433 34-37 IN denotes for
T434 38-52 JJ denotes proprioceptive
T435 53-59 NN denotes neuron
T436 60-68 NN denotes survival
T437 68-69 . denotes .
T438 69-233 sentence denotes Deletion of the proapoptotic gene Bax in NT-3 knockout mice rescues these neurons and allows for examination of their axon growth in the absence of NT-3 signaling.
T439 70-78 NN denotes Deletion
T441 79-81 IN denotes of
T442 82-85 DT denotes the
T444 86-98 JJ denotes proapoptotic
T443 99-103 NN denotes gene
T445 104-107 NN denotes Bax
T446 108-110 IN denotes in
T447 111-113 NN denotes NT
T449 113-114 HYPH denotes -
T450 114-115 CD denotes 3
T448 116-124 NN denotes knockout
T451 125-129 NNS denotes mice
T440 130-137 VBZ denotes rescues
T452 138-143 DT denotes these
T453 144-151 NNS denotes neurons
T454 152-155 CC denotes and
T455 156-162 VBZ denotes allows
T456 163-166 IN denotes for
T457 167-178 NN denotes examination
T458 179-181 IN denotes of
T459 182-187 PRP$ denotes their
T461 188-192 NN denotes axon
T460 193-199 NN denotes growth
T462 200-202 IN denotes in
T463 203-206 DT denotes the
T464 207-214 NN denotes absence
T465 215-217 IN denotes of
T466 218-220 NN denotes NT
T468 220-221 HYPH denotes -
T469 221-222 CD denotes 3
T467 223-232 NN denotes signaling
T470 232-233 . denotes .
T471 233-403 sentence denotes TrkC-positive peripheral and central axons from dorsal root ganglia follow proper trajectories and arrive in close proximity to their targets but fail to innervate them.
T472 234-238 NN denotes TrkC
T474 238-239 HYPH denotes -
T473 239-247 JJ denotes positive
T476 248-258 JJ denotes peripheral
T477 259-262 CC denotes and
T478 263-270 JJ denotes central
T475 271-276 NNS denotes axons
T480 277-281 IN denotes from
T481 282-288 JJ denotes dorsal
T482 289-293 NN denotes root
T483 294-301 NNS denotes ganglia
T479 302-308 VBP denotes follow
T484 309-315 JJ denotes proper
T485 316-328 NNS denotes trajectories
T486 329-332 CC denotes and
T487 333-339 VBP denotes arrive
T488 340-342 IN denotes in
T489 343-348 JJ denotes close
T490 349-358 NN denotes proximity
T491 359-361 IN denotes to
T492 362-367 PRP$ denotes their
T493 368-375 NNS denotes targets
T494 376-379 CC denotes but
T495 380-384 VBP denotes fail
T496 385-387 TO denotes to
T497 388-397 VB denotes innervate
T498 398-402 PRP denotes them
T499 402-403 . denotes .
T500 403-503 sentence denotes Peripherally, muscle spindles are absent and TrkC-positive axons do not enter their target muscles.
T501 404-416 RB denotes Peripherally
T503 416-418 , denotes ,
T504 418-424 NN denotes muscle
T505 425-433 NNS denotes spindles
T502 434-437 VBP denotes are
T506 438-444 JJ denotes absent
T507 445-448 CC denotes and
T508 449-453 NN denotes TrkC
T510 453-454 HYPH denotes -
T509 454-462 JJ denotes positive
T511 463-468 NNS denotes axons
T513 469-471 VBP denotes do
T514 472-475 RB denotes not
T512 476-481 VB denotes enter
T515 482-487 PRP$ denotes their
T517 488-494 NN denotes target
T516 495-502 NNS denotes muscles
T518 502-503 . denotes .
T519 503-608 sentence denotes Centrally, proprioceptive axons branch in ectopic regions of the spinal cord, even crossing the midline.
T520 504-513 RB denotes Centrally
T522 513-515 , denotes ,
T523 515-529 JJ denotes proprioceptive
T524 530-535 NNS denotes axons
T521 536-542 VBP denotes branch
T525 543-545 IN denotes in
T526 546-553 JJ denotes ectopic
T527 554-561 NNS denotes regions
T528 562-564 IN denotes of
T529 565-568 DT denotes the
T531 569-575 JJ denotes spinal
T530 576-580 NN denotes cord
T532 580-582 , denotes ,
T533 582-586 RB denotes even
T534 587-595 VBG denotes crossing
T535 596-599 DT denotes the
T536 600-607 NN denotes midline
T537 607-608 . denotes .
T538 608-694 sentence denotes In vitro assays reveal chemoattractant effects of NT-3 on dorsal root ganglion axons.
T539 609-611 FW denotes In
T540 612-617 FW denotes vitro
T541 618-624 NNS denotes assays
T542 625-631 VBP denotes reveal
T543 632-647 NN denotes chemoattractant
T544 648-655 NNS denotes effects
T545 656-658 IN denotes of
T546 659-661 NN denotes NT
T547 661-662 HYPH denotes -
T548 662-663 CD denotes 3
T549 664-666 IN denotes on
T550 667-673 JJ denotes dorsal
T551 674-678 NN denotes root
T552 679-687 NN denotes ganglion
T553 688-693 NNS denotes axons
T554 693-694 . denotes .
T555 694-853 sentence denotes Our results show that survival factor NT-3 acts as a short-distance axon guidance molecule for muscle sensory afferents as they approach their proper targets.
T556 695-698 PRP$ denotes Our
T557 699-706 NNS denotes results
T558 707-711 VBP denotes show
T559 712-716 IN denotes that
T561 717-725 NN denotes survival
T562 726-732 NN denotes factor
T563 733-735 NN denotes NT
T564 735-736 HYPH denotes -
T565 736-737 CD denotes 3
T560 738-742 VBZ denotes acts
T566 743-745 IN denotes as
T567 746-747 DT denotes a
T569 748-753 JJ denotes short
T571 753-754 HYPH denotes -
T570 754-762 NN denotes distance
T572 763-767 NN denotes axon
T573 768-776 NN denotes guidance
T568 777-785 NN denotes molecule
T574 786-789 IN denotes for
T575 790-796 NN denotes muscle
T577 797-804 NN denotes sensory
T576 805-814 NNS denotes afferents
T578 815-817 IN denotes as
T580 818-822 PRP denotes they
T579 823-831 VBP denotes approach
T581 832-837 PRP$ denotes their
T583 838-844 JJ denotes proper
T582 845-852 NNS denotes targets
T584 852-853 . denotes .
R10 T437 T424 punct .,required
R100 T517 T516 compound target,muscles
R101 T518 T502 punct .,are
R102 T520 T521 advmod Centrally,branch
R103 T522 T521 punct ", ",branch
R104 T523 T524 amod proprioceptive,axons
R105 T524 T521 nsubj axons,branch
R106 T525 T521 prep in,branch
R107 T526 T527 amod ectopic,regions
R108 T527 T525 pobj regions,in
R109 T528 T527 prep of,regions
R11 T439 T440 nsubj Deletion,rescues
R110 T529 T530 det the,cord
R111 T530 T528 pobj cord,of
R112 T531 T530 amod spinal,cord
R113 T532 T521 punct ", ",branch
R114 T533 T534 advmod even,crossing
R115 T534 T521 advcl crossing,branch
R116 T535 T536 det the,midline
R117 T536 T534 dobj midline,crossing
R118 T537 T521 punct .,branch
R119 T539 T540 advmod In,vitro
R12 T441 T439 prep of,Deletion
R120 T540 T541 amod vitro,assays
R121 T541 T542 nsubj assays,reveal
R122 T543 T544 compound chemoattractant,effects
R123 T544 T542 dobj effects,reveal
R124 T545 T544 prep of,effects
R125 T546 T545 pobj NT,of
R126 T547 T546 punct -,NT
R127 T548 T546 nummod 3,NT
R128 T549 T544 prep on,effects
R129 T550 T551 amod dorsal,root
R13 T442 T443 det the,gene
R130 T551 T552 compound root,ganglion
R131 T552 T553 compound ganglion,axons
R132 T553 T549 pobj axons,on
R133 T554 T542 punct .,reveal
R134 T556 T557 poss Our,results
R135 T557 T558 nsubj results,show
R136 T559 T560 mark that,acts
R137 T560 T558 ccomp acts,show
R138 T561 T562 compound survival,factor
R139 T562 T563 compound factor,NT
R14 T443 T441 pobj gene,of
R140 T563 T560 nsubj NT,acts
R141 T564 T563 punct -,NT
R142 T565 T563 nummod 3,NT
R143 T566 T560 prep as,acts
R144 T567 T568 det a,molecule
R145 T568 T566 pobj molecule,as
R146 T569 T570 amod short,distance
R147 T570 T568 compound distance,molecule
R148 T571 T570 punct -,distance
R149 T572 T573 compound axon,guidance
R15 T444 T443 amod proapoptotic,gene
R150 T573 T568 compound guidance,molecule
R151 T574 T560 prep for,acts
R152 T575 T576 compound muscle,afferents
R153 T576 T574 pobj afferents,for
R154 T577 T576 compound sensory,afferents
R155 T578 T579 mark as,approach
R156 T579 T560 advcl approach,acts
R157 T580 T579 nsubj they,approach
R158 T581 T582 poss their,targets
R159 T582 T579 dobj targets,approach
R16 T445 T443 appos Bax,gene
R160 T583 T582 amod proper,targets
R161 T584 T558 punct .,show
R17 T446 T439 prep in,Deletion
R18 T447 T448 nmod NT,knockout
R19 T448 T451 compound knockout,mice
R2 T429 T428 punct -,NT
R20 T449 T447 punct -,NT
R21 T450 T447 nummod 3,NT
R22 T451 T446 pobj mice,in
R23 T452 T453 det these,neurons
R24 T453 T440 dobj neurons,rescues
R25 T454 T440 cc and,rescues
R26 T455 T440 conj allows,rescues
R27 T456 T455 prep for,allows
R28 T457 T456 pobj examination,for
R29 T458 T457 prep of,examination
R3 T430 T428 nummod 3,NT
R30 T459 T460 poss their,growth
R31 T460 T458 pobj growth,of
R32 T461 T460 compound axon,growth
R33 T462 T455 prep in,allows
R34 T463 T464 det the,absence
R35 T464 T462 pobj absence,in
R36 T465 T464 prep of,absence
R37 T466 T467 nmod NT,signaling
R38 T467 T465 pobj signaling,of
R39 T468 T466 punct -,NT
R4 T431 T424 punct ),required
R40 T469 T466 nummod 3,NT
R41 T470 T440 punct .,rescues
R42 T472 T473 npadvmod TrkC,positive
R43 T473 T475 amod positive,axons
R44 T474 T473 punct -,positive
R45 T475 T479 nsubj axons,follow
R46 T476 T475 amod peripheral,axons
R47 T477 T476 cc and,peripheral
R48 T478 T476 conj central,peripheral
R49 T480 T475 prep from,axons
R5 T432 T424 auxpass is,required
R50 T481 T482 amod dorsal,root
R51 T482 T483 compound root,ganglia
R52 T483 T480 pobj ganglia,from
R53 T484 T485 amod proper,trajectories
R54 T485 T479 dobj trajectories,follow
R55 T486 T479 cc and,follow
R56 T487 T479 conj arrive,follow
R57 T488 T487 prep in,arrive
R58 T489 T490 amod close,proximity
R59 T490 T488 pobj proximity,in
R6 T433 T424 prep for,required
R60 T491 T490 prep to,proximity
R61 T492 T493 poss their,targets
R62 T493 T491 pobj targets,to
R7 T434 T435 amod proprioceptive,neuron
R79 T494 T479 cc but,follow
R8 T435 T436 compound neuron,survival
R80 T495 T479 conj fail,follow
R81 T496 T497 aux to,innervate
R82 T497 T495 xcomp innervate,fail
R83 T498 T497 dobj them,innervate
R84 T499 T479 punct .,follow
R85 T501 T502 advmod Peripherally,are
R86 T503 T502 punct ", ",are
R87 T504 T505 compound muscle,spindles
R88 T505 T502 nsubj spindles,are
R89 T506 T502 acomp absent,are
R9 T436 T433 pobj survival,for
R90 T507 T502 cc and,are
R91 T508 T509 npadvmod TrkC,positive
R92 T509 T511 amod positive,axons
R93 T510 T509 punct -,positive
R94 T511 T512 nsubj axons,enter
R95 T512 T502 conj enter,are
R96 T513 T512 aux do,enter
R97 T514 T512 neg not,enter
R98 T515 T516 poss their,muscles
R99 T516 T512 dobj muscles,enter