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PMC:523229 / 41599-42265 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T9436 0-2 IN denotes At
T9438 3-7 DT denotes some
T9439 8-13 NNS denotes sites
T9440 13-15 , denotes ,
T9441 15-19 NN denotes loss
T9442 20-22 IN denotes of
T9443 23-29 NN denotes Bmpr1a
T9444 30-38 NN denotes function
T9437 39-44 VBZ denotes leads
T9445 45-47 IN denotes to
T9446 48-49 DT denotes a
T9447 50-56 NN denotes defect
T9448 57-59 IN denotes in
T9449 60-63 DT denotes the
T9451 64-69 JJ denotes early
T9450 70-76 NNS denotes stages
T9452 77-79 IN denotes of
T9453 80-85 NN denotes joint
T9454 86-95 NN denotes formation
T9455 95-97 , denotes ,
T9456 97-106 VBG denotes resulting
T9457 107-109 IN denotes in
T9458 110-111 DT denotes a
T9460 112-120 JJ denotes complete
T9459 121-128 NN denotes failure
T9461 129-131 TO denotes to
T9462 132-136 VB denotes form
T9463 137-138 DT denotes a
T9464 139-144 NN denotes joint
T9465 145-148 CC denotes and
T9466 149-155 NN denotes fusion
T9467 156-158 IN denotes of
T9468 159-164 NNS denotes bones
T9469 165-167 IN denotes in
T9470 168-171 DT denotes the
T9471 172-177 NN denotes ankle
T9472 177-178 . denotes .
T9473 178-472 sentence denotes Mutations in two different ligands in the BMP family, Gdf5 and Gdf6, the Bmpr1b receptor, and in the human Noggin locus (Storm and Kingsley 1996; Gong et al. 1999; Baur et al. 2000; Yi et al. 2000; Settle et al. 2003) also produce defects in joint formation at specific locations in the limbs.
T9474 179-188 NNS denotes Mutations
T9476 189-191 IN denotes in
T9477 192-195 CD denotes two
T9479 196-205 JJ denotes different
T9478 206-213 NNS denotes ligands
T9480 214-216 IN denotes in
T9481 217-220 DT denotes the
T9483 221-224 NN denotes BMP
T9482 225-231 NN denotes family
T9484 231-233 , denotes ,
T9485 233-237 NN denotes Gdf5
T9486 238-241 CC denotes and
T9487 242-246 NN denotes Gdf6
T9488 246-248 , denotes ,
T9489 248-251 DT denotes the
T9491 252-258 NN denotes Bmpr1b
T9490 259-267 NN denotes receptor
T9492 267-269 , denotes ,
T9493 269-272 CC denotes and
T9494 273-275 IN denotes in
T9495 276-279 DT denotes the
T9497 280-285 JJ denotes human
T9498 286-292 NN denotes Noggin
T9496 293-298 NN denotes locus
T9499 299-300 -LRB- denotes (
T9500 300-305 NNP denotes Storm
T9501 306-309 CC denotes and
T9502 310-318 NNP denotes Kingsley
T9503 319-323 CD denotes 1996
T9504 323-324 : denotes ;
T9505 325-329 NNP denotes Gong
T9506 330-332 FW denotes et
T9507 333-336 FW denotes al.
T9508 337-341 CD denotes 1999
T9509 341-342 : denotes ;
T9510 343-347 NNP denotes Baur
T9511 348-350 FW denotes et
T9512 351-354 FW denotes al.
T9513 355-359 CD denotes 2000
T9514 359-360 : denotes ;
T9515 361-363 NNP denotes Yi
T9516 364-366 FW denotes et
T9517 367-370 FW denotes al.
T9518 371-375 CD denotes 2000
T9519 375-376 : denotes ;
T9520 377-383 NNP denotes Settle
T9521 384-386 FW denotes et
T9522 387-390 FW denotes al.
T9523 391-395 CD denotes 2003
T9524 395-396 -RRB- denotes )
T9525 397-401 RB denotes also
T9475 402-409 VBP denotes produce
T9526 410-417 NNS denotes defects
T9527 418-420 IN denotes in
T9528 421-426 NN denotes joint
T9529 427-436 NN denotes formation
T9530 437-439 IN denotes at
T9531 440-448 JJ denotes specific
T9532 449-458 NNS denotes locations
T9533 459-461 IN denotes in
T9534 462-465 DT denotes the
T9535 466-471 NNS denotes limbs
T9536 471-472 . denotes .
T9537 472-666 sentence denotes The joint defects associated with multiple components of the BMP pathway provide strong evidence that BMP signaling is required for early stages of joint formation at some anatomical locations.
T9538 473-476 DT denotes The
T9540 477-482 NN denotes joint
T9539 483-490 NNS denotes defects
T9542 491-501 VBN denotes associated
T9543 502-506 IN denotes with
T9544 507-515 JJ denotes multiple
T9545 516-526 NNS denotes components
T9546 527-529 IN denotes of
T9547 530-533 DT denotes the
T9549 534-537 NN denotes BMP
T9548 538-545 NN denotes pathway
T9541 546-553 VBP denotes provide
T9550 554-560 JJ denotes strong
T9551 561-569 NN denotes evidence
T9552 570-574 IN denotes that
T9554 575-578 NN denotes BMP
T9555 579-588 NN denotes signaling
T9556 589-591 VBZ denotes is
T9553 592-600 VBN denotes required
T9557 601-604 IN denotes for
T9558 605-610 JJ denotes early
T9559 611-617 NNS denotes stages
T9560 618-620 IN denotes of
T9561 621-626 NN denotes joint
T9562 627-636 NN denotes formation
T9563 637-639 IN denotes at
T9564 640-644 DT denotes some
T9566 645-655 JJ denotes anatomical
T9565 656-665 NNS denotes locations
T9567 665-666 . denotes .
R5732 T9436 T9437 prep At,leads
R5733 T9438 T9439 det some,sites
R5734 T9439 T9436 pobj sites,At
R5735 T9440 T9437 punct ", ",leads
R5736 T9441 T9437 nsubj loss,leads
R5737 T9442 T9441 prep of,loss
R5738 T9443 T9444 compound Bmpr1a,function
R5739 T9444 T9442 pobj function,of
R5740 T9445 T9437 prep to,leads
R5741 T9446 T9447 det a,defect
R5742 T9447 T9445 pobj defect,to
R5743 T9448 T9447 prep in,defect
R5744 T9449 T9450 det the,stages
R5745 T9450 T9448 pobj stages,in
R5746 T9451 T9450 amod early,stages
R5747 T9452 T9450 prep of,stages
R5748 T9453 T9454 compound joint,formation
R5749 T9454 T9452 pobj formation,of
R5750 T9455 T9437 punct ", ",leads
R5751 T9456 T9437 advcl resulting,leads
R5752 T9457 T9456 prep in,resulting
R5753 T9458 T9459 det a,failure
R5754 T9459 T9457 pobj failure,in
R5755 T9460 T9459 amod complete,failure
R5756 T9461 T9462 aux to,form
R5757 T9462 T9459 acl form,failure
R5758 T9463 T9464 det a,joint
R5759 T9464 T9462 dobj joint,form
R5760 T9465 T9459 cc and,failure
R5761 T9466 T9459 conj fusion,failure
R5762 T9467 T9466 prep of,fusion
R5763 T9468 T9467 pobj bones,of
R5764 T9469 T9466 prep in,fusion
R5765 T9470 T9471 det the,ankle
R5766 T9471 T9469 pobj ankle,in
R5767 T9472 T9437 punct .,leads
R5768 T9474 T9475 nsubj Mutations,produce
R5769 T9476 T9474 prep in,Mutations
R5770 T9477 T9478 nummod two,ligands
R5771 T9478 T9476 pobj ligands,in
R5772 T9479 T9478 amod different,ligands
R5773 T9480 T9478 prep in,ligands
R5774 T9481 T9482 det the,family
R5775 T9482 T9480 pobj family,in
R5776 T9483 T9482 compound BMP,family
R5777 T9484 T9478 punct ", ",ligands
R5778 T9485 T9478 appos Gdf5,ligands
R5779 T9486 T9485 cc and,Gdf5
R5780 T9487 T9485 conj Gdf6,Gdf5
R5781 T9488 T9478 punct ", ",ligands
R5782 T9489 T9490 det the,receptor
R5783 T9490 T9478 appos receptor,ligands
R5784 T9491 T9490 compound Bmpr1b,receptor
R5785 T9492 T9476 punct ", ",in
R5786 T9493 T9476 cc and,in
R5787 T9494 T9476 conj in,in
R5788 T9495 T9496 det the,locus
R5789 T9496 T9494 pobj locus,in
R5790 T9497 T9496 amod human,locus
R5791 T9498 T9496 compound Noggin,locus
R5792 T9499 T9500 punct (,Storm
R5793 T9500 T9474 meta Storm,Mutations
R5794 T9501 T9500 cc and,Storm
R5795 T9502 T9500 conj Kingsley,Storm
R5796 T9503 T9502 nummod 1996,Kingsley
R5797 T9504 T9502 punct ;,Kingsley
R5798 T9505 T9502 conj Gong,Kingsley
R5799 T9506 T9505 nmod et,Gong
R5800 T9507 T9505 nmod al.,Gong
R5801 T9508 T9505 nummod 1999,Gong
R5802 T9509 T9505 punct ;,Gong
R5803 T9510 T9505 conj Baur,Gong
R5804 T9511 T9510 nmod et,Baur
R5805 T9512 T9510 nmod al.,Baur
R5806 T9513 T9510 nummod 2000,Baur
R5807 T9514 T9510 punct ;,Baur
R5808 T9515 T9510 conj Yi,Baur
R5809 T9516 T9515 nmod et,Yi
R5810 T9517 T9515 nmod al.,Yi
R5811 T9518 T9515 nummod 2000,Yi
R5812 T9519 T9515 punct ;,Yi
R5813 T9520 T9515 conj Settle,Yi
R5814 T9521 T9520 nmod et,Settle
R5815 T9522 T9520 nmod al.,Settle
R5816 T9523 T9520 nummod 2003,Settle
R5817 T9524 T9520 punct ),Settle
R5818 T9525 T9475 advmod also,produce
R5819 T9526 T9475 dobj defects,produce
R5820 T9527 T9526 prep in,defects
R5821 T9528 T9529 compound joint,formation
R5822 T9529 T9527 pobj formation,in
R5823 T9530 T9475 prep at,produce
R5824 T9531 T9532 amod specific,locations
R5825 T9532 T9530 pobj locations,at
R5826 T9533 T9532 prep in,locations
R5827 T9534 T9535 det the,limbs
R5828 T9535 T9533 pobj limbs,in
R5829 T9536 T9475 punct .,produce
R5830 T9538 T9539 det The,defects
R5831 T9539 T9541 nsubj defects,provide
R5832 T9540 T9539 compound joint,defects
R5833 T9542 T9539 acl associated,defects
R5834 T9543 T9542 prep with,associated
R5835 T9544 T9545 amod multiple,components
R5836 T9545 T9543 pobj components,with
R5837 T9546 T9545 prep of,components
R5838 T9547 T9548 det the,pathway
R5839 T9548 T9546 pobj pathway,of
R5840 T9549 T9548 compound BMP,pathway
R5841 T9550 T9551 amod strong,evidence
R5842 T9551 T9541 dobj evidence,provide
R5843 T9552 T9553 mark that,required
R5844 T9553 T9551 acl required,evidence
R5845 T9554 T9555 compound BMP,signaling
R5846 T9555 T9553 nsubjpass signaling,required
R5847 T9556 T9553 auxpass is,required
R5848 T9557 T9553 prep for,required
R5849 T9558 T9559 amod early,stages
R5850 T9559 T9557 pobj stages,for
R5851 T9560 T9559 prep of,stages
R5852 T9561 T9562 compound joint,formation
R5853 T9562 T9560 pobj formation,of
R5854 T9563 T9553 prep at,required
R5855 T9564 T9565 det some,locations
R5856 T9565 T9563 pobj locations,at
R5857 T9566 T9565 amod anatomical,locations
R5858 T9567 T9541 punct .,provide