Id |
Subject |
Object |
Predicate |
Lexical cue |
T3400 |
0-5 |
JJ |
denotes |
Other |
T3401 |
6-11 |
NNS |
denotes |
sites |
T3403 |
12-19 |
IN |
denotes |
besides |
T3404 |
20-24 |
NN |
denotes |
limb |
T3405 |
25-31 |
NNS |
denotes |
joints |
T3406 |
32-36 |
RB |
denotes |
also |
T3402 |
37-41 |
VBP |
denotes |
have |
T3407 |
42-45 |
NN |
denotes |
Cre |
T3409 |
45-46 |
HYPH |
denotes |
- |
T3408 |
46-54 |
VBN |
denotes |
mediated |
T3411 |
55-59 |
NN |
denotes |
lacZ |
T3410 |
60-70 |
NN |
denotes |
expression |
T3412 |
70-71 |
. |
denotes |
. |
T3413 |
71-181 |
sentence |
denotes |
Starting at E13.5, LACZ activity is detected in an anterior and posterior domain of the limb bud (Figure 2C). |
T3414 |
72-80 |
VBG |
denotes |
Starting |
T3416 |
81-83 |
IN |
denotes |
at |
T3417 |
84-89 |
NN |
denotes |
E13.5 |
T3418 |
89-91 |
, |
denotes |
, |
T3419 |
91-95 |
NN |
denotes |
LACZ |
T3420 |
96-104 |
NN |
denotes |
activity |
T3421 |
105-107 |
VBZ |
denotes |
is |
T3415 |
108-116 |
VBN |
denotes |
detected |
T3422 |
117-119 |
IN |
denotes |
in |
T3423 |
120-122 |
DT |
denotes |
an |
T3425 |
123-131 |
JJ |
denotes |
anterior |
T3426 |
132-135 |
CC |
denotes |
and |
T3427 |
136-145 |
JJ |
denotes |
posterior |
T3424 |
146-152 |
NN |
denotes |
domain |
T3428 |
153-155 |
IN |
denotes |
of |
T3429 |
156-159 |
DT |
denotes |
the |
T3431 |
160-164 |
NN |
denotes |
limb |
T3430 |
165-168 |
NN |
denotes |
bud |
T3432 |
169-170 |
-LRB- |
denotes |
( |
T3433 |
170-176 |
NN |
denotes |
Figure |
T3434 |
177-179 |
CD |
denotes |
2C |
T3435 |
179-180 |
-RRB- |
denotes |
) |
T3436 |
180-181 |
. |
denotes |
. |
T3437 |
181-363 |
sentence |
denotes |
At E14.5, LACZ activity is detectable in the developing ear pinnae, ribs, sternum, tissues in the face, and some regions of the brain and spinal cord (Figure 1B) (unpublished data). |
T3438 |
182-184 |
IN |
denotes |
At |
T3440 |
185-190 |
NN |
denotes |
E14.5 |
T3441 |
190-192 |
, |
denotes |
, |
T3442 |
192-196 |
NN |
denotes |
LACZ |
T3443 |
197-205 |
NN |
denotes |
activity |
T3439 |
206-208 |
VBZ |
denotes |
is |
T3444 |
209-219 |
JJ |
denotes |
detectable |
T3445 |
220-222 |
IN |
denotes |
in |
T3446 |
223-226 |
DT |
denotes |
the |
T3448 |
227-237 |
VBG |
denotes |
developing |
T3449 |
238-241 |
NN |
denotes |
ear |
T3447 |
242-248 |
NNS |
denotes |
pinnae |
T3450 |
248-250 |
, |
denotes |
, |
T3451 |
250-254 |
NNS |
denotes |
ribs |
T3452 |
254-256 |
, |
denotes |
, |
T3453 |
256-263 |
NN |
denotes |
sternum |
T3454 |
263-265 |
, |
denotes |
, |
T3455 |
265-272 |
NNS |
denotes |
tissues |
T3456 |
273-275 |
IN |
denotes |
in |
T3457 |
276-279 |
DT |
denotes |
the |
T3458 |
280-284 |
NN |
denotes |
face |
T3459 |
284-286 |
, |
denotes |
, |
T3460 |
286-289 |
CC |
denotes |
and |
T3461 |
290-294 |
DT |
denotes |
some |
T3462 |
295-302 |
NNS |
denotes |
regions |
T3463 |
303-305 |
IN |
denotes |
of |
T3464 |
306-309 |
DT |
denotes |
the |
T3465 |
310-315 |
NN |
denotes |
brain |
T3466 |
316-319 |
CC |
denotes |
and |
T3467 |
320-326 |
JJ |
denotes |
spinal |
T3468 |
327-331 |
NN |
denotes |
cord |
T3469 |
332-333 |
-LRB- |
denotes |
( |
T3470 |
333-339 |
NN |
denotes |
Figure |
T3471 |
340-342 |
CD |
denotes |
1B |
T3472 |
342-343 |
-RRB- |
denotes |
) |
T3473 |
344-345 |
-LRB- |
denotes |
( |
T3475 |
345-356 |
JJ |
denotes |
unpublished |
T3474 |
357-361 |
NNS |
denotes |
data |
T3476 |
361-362 |
-RRB- |
denotes |
) |
T3477 |
362-363 |
. |
denotes |
. |
T3478 |
363-545 |
sentence |
denotes |
At birth, LACZ is also expressed in tendons running along the vertebral column, regions of tendons in the wrist and ankle, and some tendon insertions (Figure 1D) (unpublished data). |
T3479 |
364-366 |
IN |
denotes |
At |
T3481 |
367-372 |
NN |
denotes |
birth |
T3482 |
372-374 |
, |
denotes |
, |
T3483 |
374-378 |
NN |
denotes |
LACZ |
T3484 |
379-381 |
VBZ |
denotes |
is |
T3485 |
382-386 |
RB |
denotes |
also |
T3480 |
387-396 |
VBN |
denotes |
expressed |
T3486 |
397-399 |
IN |
denotes |
in |
T3487 |
400-407 |
NNS |
denotes |
tendons |
T3488 |
408-415 |
VBG |
denotes |
running |
T3489 |
416-421 |
IN |
denotes |
along |
T3490 |
422-425 |
DT |
denotes |
the |
T3492 |
426-435 |
JJ |
denotes |
vertebral |
T3491 |
436-442 |
NN |
denotes |
column |
T3493 |
442-444 |
, |
denotes |
, |
T3494 |
444-451 |
NNS |
denotes |
regions |
T3495 |
452-454 |
IN |
denotes |
of |
T3496 |
455-462 |
NNS |
denotes |
tendons |
T3497 |
463-465 |
IN |
denotes |
in |
T3498 |
466-469 |
DT |
denotes |
the |
T3499 |
470-475 |
NN |
denotes |
wrist |
T3500 |
476-479 |
CC |
denotes |
and |
T3501 |
480-485 |
NN |
denotes |
ankle |
T3502 |
485-487 |
, |
denotes |
, |
T3503 |
487-490 |
CC |
denotes |
and |
T3504 |
491-495 |
DT |
denotes |
some |
T3506 |
496-502 |
NN |
denotes |
tendon |
T3505 |
503-513 |
NNS |
denotes |
insertions |
T3507 |
514-515 |
-LRB- |
denotes |
( |
T3508 |
515-521 |
NN |
denotes |
Figure |
T3509 |
522-524 |
CD |
denotes |
1D |
T3510 |
524-525 |
-RRB- |
denotes |
) |
T3511 |
526-527 |
-LRB- |
denotes |
( |
T3513 |
527-538 |
JJ |
denotes |
unpublished |
T3512 |
539-543 |
NNS |
denotes |
data |
T3514 |
543-544 |
-RRB- |
denotes |
) |
T3515 |
544-545 |
. |
denotes |
. |
T3516 |
545-734 |
sentence |
denotes |
By 5 wk of age, LACZ is also expressed in the hair follicles, ear cartilage, some cells in the growth plate of the long bones, and portions of the brain and spinal cord (unpublished data). |
T3517 |
546-548 |
IN |
denotes |
By |
T3519 |
549-550 |
CD |
denotes |
5 |
T3520 |
551-553 |
NNS |
denotes |
wk |
T3521 |
554-556 |
IN |
denotes |
of |
T3522 |
557-560 |
NN |
denotes |
age |
T3523 |
560-562 |
, |
denotes |
, |
T3524 |
562-566 |
NN |
denotes |
LACZ |
T3525 |
567-569 |
VBZ |
denotes |
is |
T3526 |
570-574 |
RB |
denotes |
also |
T3518 |
575-584 |
VBN |
denotes |
expressed |
T3527 |
585-587 |
IN |
denotes |
in |
T3528 |
588-591 |
DT |
denotes |
the |
T3530 |
592-596 |
NN |
denotes |
hair |
T3529 |
597-606 |
NNS |
denotes |
follicles |
T3531 |
606-608 |
, |
denotes |
, |
T3532 |
608-611 |
NN |
denotes |
ear |
T3533 |
612-621 |
NN |
denotes |
cartilage |
T3534 |
621-623 |
, |
denotes |
, |
T3535 |
623-627 |
DT |
denotes |
some |
T3536 |
628-633 |
NNS |
denotes |
cells |
T3537 |
634-636 |
IN |
denotes |
in |
T3538 |
637-640 |
DT |
denotes |
the |
T3540 |
641-647 |
NN |
denotes |
growth |
T3539 |
648-653 |
NN |
denotes |
plate |
T3541 |
654-656 |
IN |
denotes |
of |
T3542 |
657-660 |
DT |
denotes |
the |
T3544 |
661-665 |
JJ |
denotes |
long |
T3543 |
666-671 |
NNS |
denotes |
bones |
T3545 |
671-673 |
, |
denotes |
, |
T3546 |
673-676 |
CC |
denotes |
and |
T3547 |
677-685 |
NNS |
denotes |
portions |
T3548 |
686-688 |
IN |
denotes |
of |
T3549 |
689-692 |
DT |
denotes |
the |
T3550 |
693-698 |
NN |
denotes |
brain |
T3551 |
699-702 |
CC |
denotes |
and |
T3552 |
703-709 |
JJ |
denotes |
spinal |
T3553 |
710-714 |
NN |
denotes |
cord |
T3554 |
715-716 |
-LRB- |
denotes |
( |
T3556 |
716-727 |
JJ |
denotes |
unpublished |
T3555 |
728-732 |
NNS |
denotes |
data |
T3557 |
732-733 |
-RRB- |
denotes |
) |
T3558 |
733-734 |
. |
denotes |
. |
T3559 |
734-917 |
sentence |
denotes |
Surprisingly, 23 of 63, or 37% of transgenic mice analyzed also show some degree of wider “ectopic” LACZ expression, which can extend throughout many different tissues in the animal. |
T3560 |
735-747 |
RB |
denotes |
Surprisingly |
T3562 |
747-749 |
, |
denotes |
, |
T3563 |
749-751 |
CD |
denotes |
23 |
T3565 |
752-754 |
IN |
denotes |
of |
T3564 |
755-757 |
CD |
denotes |
63 |
T3566 |
757-759 |
, |
denotes |
, |
T3567 |
759-761 |
CC |
denotes |
or |
T3568 |
762-764 |
CD |
denotes |
37 |
T3569 |
764-765 |
NN |
denotes |
% |
T3570 |
766-768 |
IN |
denotes |
of |
T3571 |
769-779 |
JJ |
denotes |
transgenic |
T3572 |
780-784 |
NNS |
denotes |
mice |
T3573 |
785-793 |
VBN |
denotes |
analyzed |
T3574 |
794-798 |
RB |
denotes |
also |
T3561 |
799-803 |
VBP |
denotes |
show |
T3575 |
804-808 |
DT |
denotes |
some |
T3576 |
809-815 |
NN |
denotes |
degree |
T3577 |
816-818 |
IN |
denotes |
of |
T3578 |
819-824 |
JJR |
denotes |
wider |
T3580 |
825-826 |
`` |
denotes |
“ |
T3581 |
826-833 |
JJ |
denotes |
ectopic |
T3582 |
833-834 |
'' |
denotes |
” |
T3583 |
835-839 |
NN |
denotes |
LACZ |
T3579 |
840-850 |
NN |
denotes |
expression |
T3584 |
850-852 |
, |
denotes |
, |
T3585 |
852-857 |
WDT |
denotes |
which |
T3587 |
858-861 |
MD |
denotes |
can |
T3586 |
862-868 |
VB |
denotes |
extend |
T3588 |
869-879 |
IN |
denotes |
throughout |
T3589 |
880-884 |
JJ |
denotes |
many |
T3591 |
885-894 |
JJ |
denotes |
different |
T3590 |
895-902 |
NNS |
denotes |
tissues |
T3592 |
903-905 |
IN |
denotes |
in |
T3593 |
906-909 |
DT |
denotes |
the |
T3594 |
910-916 |
NN |
denotes |
animal |
T3595 |
916-917 |
. |
denotes |
. |
T3596 |
917-1151 |
sentence |
denotes |
However, sustained expression of the transgene itself, as assayed by HPLAP activity, is still restricted primarily to joints in animals that show evidence of more generalized recombination based on LACZ expression (unpublished data). |
T3597 |
918-925 |
RB |
denotes |
However |
T3599 |
925-927 |
, |
denotes |
, |
T3600 |
927-936 |
VBN |
denotes |
sustained |
T3601 |
937-947 |
NN |
denotes |
expression |
T3602 |
948-950 |
IN |
denotes |
of |
T3603 |
951-954 |
DT |
denotes |
the |
T3604 |
955-964 |
NN |
denotes |
transgene |
T3605 |
965-971 |
PRP |
denotes |
itself |
T3606 |
971-973 |
, |
denotes |
, |
T3607 |
973-975 |
IN |
denotes |
as |
T3608 |
976-983 |
VBN |
denotes |
assayed |
T3609 |
984-986 |
IN |
denotes |
by |
T3610 |
987-992 |
NN |
denotes |
HPLAP |
T3611 |
993-1001 |
NN |
denotes |
activity |
T3612 |
1001-1003 |
, |
denotes |
, |
T3598 |
1003-1005 |
VBZ |
denotes |
is |
T3613 |
1006-1011 |
RB |
denotes |
still |
T3614 |
1012-1022 |
VBN |
denotes |
restricted |
T3615 |
1023-1032 |
RB |
denotes |
primarily |
T3616 |
1033-1035 |
IN |
denotes |
to |
T3617 |
1036-1042 |
NNS |
denotes |
joints |
T3618 |
1043-1045 |
IN |
denotes |
in |
T3619 |
1046-1053 |
NNS |
denotes |
animals |
T3620 |
1054-1058 |
WDT |
denotes |
that |
T3621 |
1059-1063 |
VBP |
denotes |
show |
T3622 |
1064-1072 |
NN |
denotes |
evidence |
T3623 |
1073-1075 |
IN |
denotes |
of |
T3624 |
1076-1080 |
RBR |
denotes |
more |
T3625 |
1081-1092 |
VBN |
denotes |
generalized |
T3626 |
1093-1106 |
NN |
denotes |
recombination |
T3627 |
1107-1112 |
VBN |
denotes |
based |
T3628 |
1113-1115 |
IN |
denotes |
on |
T3629 |
1116-1120 |
NN |
denotes |
LACZ |
T3630 |
1121-1131 |
NN |
denotes |
expression |
T3631 |
1132-1133 |
-LRB- |
denotes |
( |
T3633 |
1133-1144 |
JJ |
denotes |
unpublished |
T3632 |
1145-1149 |
NNS |
denotes |
data |
T3634 |
1149-1150 |
-RRB- |
denotes |
) |
T3635 |
1150-1151 |
. |
denotes |
. |
T3636 |
1151-1330 |
sentence |
denotes |
This suggests that in a fraction of animals, sporadic expression of Cre at some time early in development is sufficient to lead to both ectopic recombination and LACZ expression. |
T3637 |
1152-1156 |
DT |
denotes |
This |
T3638 |
1157-1165 |
VBZ |
denotes |
suggests |
T3639 |
1166-1170 |
IN |
denotes |
that |
T3641 |
1171-1173 |
IN |
denotes |
in |
T3642 |
1174-1175 |
DT |
denotes |
a |
T3643 |
1176-1184 |
NN |
denotes |
fraction |
T3644 |
1185-1187 |
IN |
denotes |
of |
T3645 |
1188-1195 |
NNS |
denotes |
animals |
T3646 |
1195-1197 |
, |
denotes |
, |
T3647 |
1197-1205 |
JJ |
denotes |
sporadic |
T3648 |
1206-1216 |
NN |
denotes |
expression |
T3649 |
1217-1219 |
IN |
denotes |
of |
T3650 |
1220-1223 |
NN |
denotes |
Cre |
T3651 |
1224-1226 |
IN |
denotes |
at |
T3652 |
1227-1231 |
DT |
denotes |
some |
T3653 |
1232-1236 |
NN |
denotes |
time |
T3654 |
1237-1242 |
RB |
denotes |
early |
T3655 |
1243-1245 |
IN |
denotes |
in |
T3656 |
1246-1257 |
NN |
denotes |
development |
T3640 |
1258-1260 |
VBZ |
denotes |
is |
T3657 |
1261-1271 |
JJ |
denotes |
sufficient |
T3658 |
1272-1274 |
TO |
denotes |
to |
T3659 |
1275-1279 |
VB |
denotes |
lead |
T3660 |
1280-1282 |
IN |
denotes |
to |
T3661 |
1283-1287 |
CC |
denotes |
both |
T3663 |
1288-1295 |
JJ |
denotes |
ectopic |
T3662 |
1296-1309 |
NN |
denotes |
recombination |
T3664 |
1310-1313 |
CC |
denotes |
and |
T3665 |
1314-1318 |
NN |
denotes |
LACZ |
T3666 |
1319-1329 |
NN |
denotes |
expression |
T3667 |
1329-1330 |
. |
denotes |
. |
T3668 |
1330-1624 |
sentence |
denotes |
While the fraction of animals with broader recombination patterns must be tracked and accounted for during experiments, these animals offer the potential benefit of revealing additional new functions of target genes that could be subsequently studied with additional site-specific Cre drivers. |
T3669 |
1331-1336 |
IN |
denotes |
While |
T3671 |
1337-1340 |
DT |
denotes |
the |
T3672 |
1341-1349 |
NN |
denotes |
fraction |
T3673 |
1350-1352 |
IN |
denotes |
of |
T3674 |
1353-1360 |
NNS |
denotes |
animals |
T3675 |
1361-1365 |
IN |
denotes |
with |
T3676 |
1366-1373 |
JJR |
denotes |
broader |
T3678 |
1374-1387 |
NN |
denotes |
recombination |
T3677 |
1388-1396 |
NNS |
denotes |
patterns |
T3679 |
1397-1401 |
MD |
denotes |
must |
T3680 |
1402-1404 |
VB |
denotes |
be |
T3670 |
1405-1412 |
VBN |
denotes |
tracked |
T3682 |
1413-1416 |
CC |
denotes |
and |
T3683 |
1417-1426 |
VBN |
denotes |
accounted |
T3684 |
1427-1430 |
IN |
denotes |
for |
T3685 |
1431-1437 |
IN |
denotes |
during |
T3686 |
1438-1449 |
NNS |
denotes |
experiments |
T3687 |
1449-1451 |
, |
denotes |
, |
T3688 |
1451-1456 |
DT |
denotes |
these |
T3689 |
1457-1464 |
NNS |
denotes |
animals |
T3681 |
1465-1470 |
VBP |
denotes |
offer |
T3690 |
1471-1474 |
DT |
denotes |
the |
T3692 |
1475-1484 |
JJ |
denotes |
potential |
T3691 |
1485-1492 |
NN |
denotes |
benefit |
T3693 |
1493-1495 |
IN |
denotes |
of |
T3694 |
1496-1505 |
VBG |
denotes |
revealing |
T3695 |
1506-1516 |
JJ |
denotes |
additional |
T3697 |
1517-1520 |
JJ |
denotes |
new |
T3696 |
1521-1530 |
NNS |
denotes |
functions |
T3698 |
1531-1533 |
IN |
denotes |
of |
T3699 |
1534-1540 |
NN |
denotes |
target |
T3700 |
1541-1546 |
NNS |
denotes |
genes |
T3701 |
1547-1551 |
WDT |
denotes |
that |
T3703 |
1552-1557 |
MD |
denotes |
could |
T3704 |
1558-1560 |
VB |
denotes |
be |
T3705 |
1561-1573 |
RB |
denotes |
subsequently |
T3702 |
1574-1581 |
VBN |
denotes |
studied |
T3706 |
1582-1586 |
IN |
denotes |
with |
T3707 |
1587-1597 |
JJ |
denotes |
additional |
T3709 |
1598-1602 |
NN |
denotes |
site |
T3710 |
1602-1603 |
HYPH |
denotes |
- |
T3711 |
1603-1611 |
JJ |
denotes |
specific |
T3712 |
1612-1615 |
NN |
denotes |
Cre |
T3708 |
1616-1623 |
NNS |
denotes |
drivers |
T3713 |
1623-1624 |
. |
denotes |
. |
R2075 |
T3479 |
T3480 |
prep |
At,expressed |
R2076 |
T3481 |
T3479 |
pobj |
birth,At |
R2077 |
T3482 |
T3480 |
punct |
", ",expressed |
R2078 |
T3483 |
T3480 |
nsubjpass |
LACZ,expressed |
R2079 |
T3484 |
T3480 |
auxpass |
is,expressed |
R2081 |
T3485 |
T3480 |
advmod |
also,expressed |
R2083 |
T3486 |
T3480 |
prep |
in,expressed |
R2089 |
T3487 |
T3486 |
pobj |
tendons,in |
R2095 |
T3488 |
T3487 |
acl |
running,tendons |
R2099 |
T3489 |
T3488 |
prep |
along,running |
R2101 |
T3490 |
T3491 |
det |
the,column |
R2102 |
T3491 |
T3489 |
pobj |
column,along |
R2106 |
T3492 |
T3491 |
amod |
vertebral,column |
R2109 |
T3493 |
T3487 |
punct |
", ",tendons |
R2113 |
T3494 |
T3487 |
conj |
regions,tendons |
R2116 |
T3495 |
T3494 |
prep |
of,regions |
R2117 |
T3400 |
T3401 |
amod |
Other,sites |
R2118 |
T3496 |
T3495 |
pobj |
tendons,of |
R2119 |
T3401 |
T3402 |
nsubj |
sites,have |
R2120 |
T3497 |
T3494 |
prep |
in,regions |
R2121 |
T3403 |
T3401 |
prep |
besides,sites |
R2122 |
T3404 |
T3405 |
compound |
limb,joints |
R2123 |
T3498 |
T3499 |
det |
the,wrist |
R2124 |
T3405 |
T3403 |
pobj |
joints,besides |
R2125 |
T3406 |
T3402 |
advmod |
also,have |
R2126 |
T3407 |
T3408 |
npadvmod |
Cre,mediated |
R2127 |
T3408 |
T3410 |
amod |
mediated,expression |
R2128 |
T3499 |
T3497 |
pobj |
wrist,in |
R2129 |
T3409 |
T3408 |
punct |
-,mediated |
R2130 |
T3410 |
T3402 |
dobj |
expression,have |
R2131 |
T3411 |
T3410 |
compound |
lacZ,expression |
R2132 |
T3500 |
T3499 |
cc |
and,wrist |
R2133 |
T3412 |
T3402 |
punct |
.,have |
R2134 |
T3414 |
T3415 |
advcl |
Starting,detected |
R2135 |
T3501 |
T3499 |
conj |
ankle,wrist |
R2136 |
T3416 |
T3414 |
prep |
at,Starting |
R2137 |
T3502 |
T3494 |
punct |
", ",regions |
R2138 |
T3417 |
T3416 |
pobj |
E13.5,at |
R2139 |
T3418 |
T3415 |
punct |
", ",detected |
R2140 |
T3419 |
T3420 |
compound |
LACZ,activity |
R2141 |
T3420 |
T3415 |
nsubjpass |
activity,detected |
R2142 |
T3421 |
T3415 |
auxpass |
is,detected |
R2143 |
T3422 |
T3415 |
prep |
in,detected |
R2144 |
T3423 |
T3424 |
det |
an,domain |
R2145 |
T3503 |
T3494 |
cc |
and,regions |
R2146 |
T3424 |
T3422 |
pobj |
domain,in |
R2147 |
T3425 |
T3424 |
amod |
anterior,domain |
R2148 |
T3426 |
T3425 |
cc |
and,anterior |
R2149 |
T3427 |
T3425 |
conj |
posterior,anterior |
R2150 |
T3504 |
T3505 |
det |
some,insertions |
R2151 |
T3428 |
T3424 |
prep |
of,domain |
R2152 |
T3429 |
T3430 |
det |
the,bud |
R2153 |
T3505 |
T3494 |
conj |
insertions,regions |
R2154 |
T3430 |
T3428 |
pobj |
bud,of |
R2155 |
T3431 |
T3430 |
compound |
limb,bud |
R2156 |
T3432 |
T3433 |
punct |
(,Figure |
R2157 |
T3506 |
T3505 |
compound |
tendon,insertions |
R2158 |
T3433 |
T3415 |
parataxis |
Figure,detected |
R2159 |
T3434 |
T3433 |
nummod |
2C,Figure |
R2160 |
T3435 |
T3433 |
punct |
),Figure |
R2161 |
T3507 |
T3508 |
punct |
(,Figure |
R2162 |
T3436 |
T3415 |
punct |
.,detected |
R2163 |
T3438 |
T3439 |
prep |
At,is |
R2164 |
T3508 |
T3480 |
parataxis |
Figure,expressed |
R2165 |
T3440 |
T3438 |
pobj |
E14.5,At |
R2166 |
T3441 |
T3439 |
punct |
", ",is |
R2167 |
T3509 |
T3508 |
nummod |
1D,Figure |
R2168 |
T3442 |
T3443 |
compound |
LACZ,activity |
R2169 |
T3443 |
T3439 |
nsubj |
activity,is |
R2170 |
T3510 |
T3508 |
punct |
),Figure |
R2171 |
T3444 |
T3439 |
acomp |
detectable,is |
R2172 |
T3445 |
T3439 |
prep |
in,is |
R2173 |
T3446 |
T3447 |
det |
the,pinnae |
R2174 |
T3511 |
T3512 |
punct |
(,data |
R2175 |
T3447 |
T3445 |
pobj |
pinnae,in |
R2176 |
T3448 |
T3447 |
amod |
developing,pinnae |
R2177 |
T3449 |
T3447 |
compound |
ear,pinnae |
R2178 |
T3512 |
T3480 |
meta |
data,expressed |
R2179 |
T3450 |
T3447 |
punct |
", ",pinnae |
R2180 |
T3451 |
T3447 |
appos |
ribs,pinnae |
R2181 |
T3513 |
T3512 |
amod |
unpublished,data |
R2182 |
T3452 |
T3447 |
punct |
", ",pinnae |
R2183 |
T3453 |
T3447 |
appos |
sternum,pinnae |
R2184 |
T3454 |
T3447 |
punct |
", ",pinnae |
R2185 |
T3514 |
T3512 |
punct |
),data |
R2186 |
T3455 |
T3447 |
appos |
tissues,pinnae |
R2187 |
T3456 |
T3439 |
prep |
in,is |
R2188 |
T3457 |
T3458 |
det |
the,face |
R2189 |
T3515 |
T3480 |
punct |
.,expressed |
R2190 |
T3458 |
T3456 |
pobj |
face,in |
R2191 |
T3459 |
T3458 |
punct |
", ",face |
R2192 |
T3460 |
T3458 |
cc |
and,face |
R2193 |
T3461 |
T3462 |
det |
some,regions |
R2194 |
T3462 |
T3458 |
conj |
regions,face |
R2195 |
T3463 |
T3462 |
prep |
of,regions |
R2196 |
T3517 |
T3518 |
prep |
By,expressed |
R2197 |
T3464 |
T3465 |
det |
the,brain |
R2198 |
T3465 |
T3463 |
pobj |
brain,of |
R2199 |
T3466 |
T3465 |
cc |
and,brain |
R2200 |
T3467 |
T3468 |
amod |
spinal,cord |
R2201 |
T3468 |
T3465 |
conj |
cord,brain |
R2202 |
T3519 |
T3520 |
nummod |
5,wk |
R2203 |
T3469 |
T3470 |
punct |
(,Figure |
R2204 |
T3470 |
T3439 |
parataxis |
Figure,is |
R2205 |
T3471 |
T3470 |
nummod |
1B,Figure |
R2206 |
T3472 |
T3470 |
punct |
),Figure |
R2207 |
T3473 |
T3474 |
punct |
(,data |
R2208 |
T3520 |
T3517 |
pobj |
wk,By |
R2209 |
T3474 |
T3439 |
meta |
data,is |
R2210 |
T3475 |
T3474 |
amod |
unpublished,data |
R2211 |
T3521 |
T3520 |
prep |
of,wk |
R2212 |
T3476 |
T3474 |
punct |
),data |
R2213 |
T3522 |
T3521 |
pobj |
age,of |
R2214 |
T3477 |
T3439 |
punct |
.,is |
R2215 |
T3523 |
T3518 |
punct |
", ",expressed |
R2216 |
T3524 |
T3518 |
nsubjpass |
LACZ,expressed |
R2217 |
T3525 |
T3518 |
auxpass |
is,expressed |
R2218 |
T3526 |
T3518 |
advmod |
also,expressed |
R2219 |
T3527 |
T3518 |
prep |
in,expressed |
R2220 |
T3528 |
T3529 |
det |
the,follicles |
R2221 |
T3529 |
T3527 |
pobj |
follicles,in |
R2222 |
T3530 |
T3529 |
compound |
hair,follicles |
R2223 |
T3585 |
T3586 |
dep |
which,extend |
R2224 |
T3531 |
T3529 |
punct |
", ",follicles |
R2225 |
T3586 |
T3579 |
relcl |
extend,expression |
R2226 |
T3587 |
T3586 |
aux |
can,extend |
R2227 |
T3588 |
T3586 |
prep |
throughout,extend |
R2228 |
T3532 |
T3533 |
compound |
ear,cartilage |
R2229 |
T3589 |
T3590 |
amod |
many,tissues |
R2230 |
T3590 |
T3588 |
pobj |
tissues,throughout |
R2231 |
T3591 |
T3590 |
amod |
different,tissues |
R2232 |
T3533 |
T3529 |
appos |
cartilage,follicles |
R2233 |
T3592 |
T3590 |
prep |
in,tissues |
R2234 |
T3593 |
T3594 |
det |
the,animal |
R2235 |
T3594 |
T3592 |
pobj |
animal,in |
R2236 |
T3534 |
T3529 |
punct |
", ",follicles |
R2237 |
T3595 |
T3561 |
punct |
.,show |
R2238 |
T3535 |
T3536 |
det |
some,cells |
R2239 |
T3597 |
T3598 |
advmod |
However,is |
R2240 |
T3599 |
T3598 |
punct |
", ",is |
R2241 |
T3536 |
T3529 |
conj |
cells,follicles |
R2242 |
T3600 |
T3601 |
amod |
sustained,expression |
R2243 |
T3601 |
T3598 |
nsubj |
expression,is |
R2244 |
T3602 |
T3601 |
prep |
of,expression |
R2245 |
T3603 |
T3604 |
det |
the,transgene |
R2246 |
T3604 |
T3602 |
pobj |
transgene,of |
R2247 |
T3605 |
T3604 |
appos |
itself,transgene |
R2248 |
T3537 |
T3536 |
prep |
in,cells |
R2249 |
T3606 |
T3598 |
punct |
", ",is |
R2250 |
T3607 |
T3608 |
mark |
as,assayed |
R2251 |
T3608 |
T3598 |
advcl |
assayed,is |
R2252 |
T3538 |
T3539 |
det |
the,plate |
R2253 |
T3609 |
T3608 |
prep |
by,assayed |
R2254 |
T3610 |
T3611 |
compound |
HPLAP,activity |
R2255 |
T3611 |
T3609 |
pobj |
activity,by |
R2256 |
T3539 |
T3537 |
pobj |
plate,in |
R2257 |
T3612 |
T3598 |
punct |
", ",is |
R2258 |
T3613 |
T3598 |
advmod |
still,is |
R2259 |
T3614 |
T3598 |
acomp |
restricted,is |
R2260 |
T3540 |
T3539 |
compound |
growth,plate |
R2261 |
T3615 |
T3616 |
advmod |
primarily,to |
R2262 |
T3616 |
T3614 |
prep |
to,restricted |
R2263 |
T3617 |
T3616 |
pobj |
joints,to |
R2264 |
T3541 |
T3539 |
prep |
of,plate |
R2265 |
T3618 |
T3617 |
prep |
in,joints |
R2266 |
T3619 |
T3618 |
pobj |
animals,in |
R2267 |
T3620 |
T3621 |
dep |
that,show |
R2268 |
T3542 |
T3543 |
det |
the,bones |
R2269 |
T3621 |
T3619 |
relcl |
show,animals |
R2270 |
T3622 |
T3621 |
dobj |
evidence,show |
R2271 |
T3623 |
T3622 |
prep |
of,evidence |
R2272 |
T3543 |
T3541 |
pobj |
bones,of |
R2273 |
T3624 |
T3625 |
advmod |
more,generalized |
R2274 |
T3625 |
T3626 |
amod |
generalized,recombination |
R2275 |
T3626 |
T3623 |
pobj |
recombination,of |
R2276 |
T3544 |
T3543 |
amod |
long,bones |
R2277 |
T3627 |
T3621 |
prep |
based,show |
R2278 |
T3628 |
T3627 |
prep |
on,based |
R2279 |
T3629 |
T3630 |
compound |
LACZ,expression |
R2280 |
T3545 |
T3536 |
punct |
", ",cells |
R2281 |
T3630 |
T3628 |
pobj |
expression,on |
R2282 |
T3631 |
T3632 |
punct |
(,data |
R2283 |
T3632 |
T3598 |
meta |
data,is |
R2284 |
T3546 |
T3536 |
cc |
and,cells |
R2285 |
T3633 |
T3632 |
amod |
unpublished,data |
R2286 |
T3634 |
T3632 |
punct |
),data |
R2287 |
T3635 |
T3598 |
punct |
.,is |
R2288 |
T3547 |
T3536 |
conj |
portions,cells |
R2289 |
T3637 |
T3638 |
nsubj |
This,suggests |
R2290 |
T3548 |
T3547 |
prep |
of,portions |
R2291 |
T3639 |
T3640 |
mark |
that,is |
R2292 |
T3549 |
T3550 |
det |
the,brain |
R2293 |
T3550 |
T3548 |
pobj |
brain,of |
R2294 |
T3640 |
T3638 |
ccomp |
is,suggests |
R2295 |
T3641 |
T3640 |
prep |
in,is |
R2296 |
T3642 |
T3643 |
det |
a,fraction |
R2297 |
T3643 |
T3641 |
pobj |
fraction,in |
R2298 |
T3644 |
T3643 |
prep |
of,fraction |
R2299 |
T3551 |
T3550 |
cc |
and,brain |
R2300 |
T3645 |
T3644 |
pobj |
animals,of |
R2301 |
T3646 |
T3640 |
punct |
", ",is |
R2302 |
T3647 |
T3648 |
amod |
sporadic,expression |
R2303 |
T3552 |
T3553 |
amod |
spinal,cord |
R2304 |
T3648 |
T3640 |
nsubj |
expression,is |
R2305 |
T3649 |
T3648 |
prep |
of,expression |
R2306 |
T3650 |
T3649 |
pobj |
Cre,of |
R2307 |
T3553 |
T3550 |
conj |
cord,brain |
R2308 |
T3651 |
T3648 |
prep |
at,expression |
R2309 |
T3652 |
T3653 |
det |
some,time |
R2310 |
T3653 |
T3651 |
pobj |
time,at |
R2311 |
T3554 |
T3555 |
punct |
(,data |
R2312 |
T3654 |
T3653 |
advmod |
early,time |
R2313 |
T3655 |
T3654 |
prep |
in,early |
R2314 |
T3656 |
T3655 |
pobj |
development,in |
R2315 |
T3555 |
T3547 |
meta |
data,portions |
R2316 |
T3657 |
T3640 |
acomp |
sufficient,is |
R2317 |
T3658 |
T3659 |
aux |
to,lead |
R2318 |
T3556 |
T3555 |
amod |
unpublished,data |
R2319 |
T3659 |
T3657 |
xcomp |
lead,sufficient |
R2320 |
T3660 |
T3659 |
prep |
to,lead |
R2321 |
T3661 |
T3662 |
preconj |
both,recombination |
R2322 |
T3557 |
T3555 |
punct |
),data |
R2323 |
T3662 |
T3660 |
pobj |
recombination,to |
R2324 |
T3663 |
T3662 |
amod |
ectopic,recombination |
R2325 |
T3664 |
T3662 |
cc |
and,recombination |
R2326 |
T3558 |
T3518 |
punct |
.,expressed |
R2327 |
T3665 |
T3666 |
compound |
LACZ,expression |
R2328 |
T3666 |
T3662 |
conj |
expression,recombination |
R2329 |
T3667 |
T3638 |
punct |
.,suggests |
R2330 |
T3560 |
T3561 |
advmod |
Surprisingly,show |
R2331 |
T3669 |
T3670 |
mark |
While,tracked |
R2332 |
T3670 |
T3681 |
advcl |
tracked,offer |
R2333 |
T3671 |
T3672 |
det |
the,fraction |
R2334 |
T3562 |
T3561 |
punct |
", ",show |
R2335 |
T3672 |
T3670 |
nsubj |
fraction,tracked |
R2336 |
T3673 |
T3672 |
prep |
of,fraction |
R2337 |
T3674 |
T3673 |
pobj |
animals,of |
R2338 |
T3563 |
T3564 |
quantmod |
23,63 |
R2339 |
T3675 |
T3674 |
prep |
with,animals |
R2340 |
T3676 |
T3677 |
amod |
broader,patterns |
R2341 |
T3677 |
T3675 |
pobj |
patterns,with |
R2342 |
T3564 |
T3561 |
nsubj |
63,show |
R2343 |
T3678 |
T3677 |
compound |
recombination,patterns |
R2344 |
T3679 |
T3670 |
aux |
must,tracked |
R2345 |
T3680 |
T3670 |
aux |
be,tracked |
R2346 |
T3682 |
T3670 |
cc |
and,tracked |
R2347 |
T3683 |
T3670 |
conj |
accounted,tracked |
R2348 |
T3565 |
T3564 |
quantmod |
of,63 |
R2349 |
T3684 |
T3683 |
prep |
for,accounted |
R2350 |
T3685 |
T3670 |
prep |
during,tracked |
R2351 |
T3686 |
T3685 |
pobj |
experiments,during |
R2352 |
T3566 |
T3564 |
punct |
", ",63 |
R2353 |
T3687 |
T3681 |
punct |
", ",offer |
R2354 |
T3688 |
T3689 |
det |
these,animals |
R2355 |
T3689 |
T3681 |
nsubj |
animals,offer |
R2356 |
T3567 |
T3564 |
cc |
or,63 |
R2357 |
T3690 |
T3691 |
det |
the,benefit |
R2358 |
T3568 |
T3569 |
nummod |
37,% |
R2359 |
T3569 |
T3564 |
conj |
%,63 |
R2360 |
T3691 |
T3681 |
dobj |
benefit,offer |
R2361 |
T3570 |
T3564 |
prep |
of,63 |
R2362 |
T3692 |
T3691 |
amod |
potential,benefit |
R2363 |
T3693 |
T3691 |
prep |
of,benefit |
R2364 |
T3694 |
T3693 |
pcomp |
revealing,of |
R2365 |
T3571 |
T3572 |
amod |
transgenic,mice |
R2366 |
T3695 |
T3696 |
amod |
additional,functions |
R2367 |
T3696 |
T3694 |
dobj |
functions,revealing |
R2368 |
T3697 |
T3696 |
amod |
new,functions |
R2369 |
T3572 |
T3570 |
pobj |
mice,of |
R2370 |
T3698 |
T3696 |
prep |
of,functions |
R2371 |
T3699 |
T3700 |
compound |
target,genes |
R2372 |
T3700 |
T3698 |
pobj |
genes,of |
R2373 |
T3573 |
T3572 |
acl |
analyzed,mice |
R2374 |
T3701 |
T3702 |
dep |
that,studied |
R2375 |
T3702 |
T3700 |
relcl |
studied,genes |
R2376 |
T3703 |
T3702 |
aux |
could,studied |
R2377 |
T3574 |
T3561 |
advmod |
also,show |
R2378 |
T3704 |
T3702 |
auxpass |
be,studied |
R2379 |
T3705 |
T3702 |
advmod |
subsequently,studied |
R2380 |
T3706 |
T3702 |
prep |
with,studied |
R2381 |
T3575 |
T3576 |
det |
some,degree |
R2382 |
T3707 |
T3708 |
amod |
additional,drivers |
R2383 |
T3708 |
T3706 |
pobj |
drivers,with |
R2384 |
T3709 |
T3708 |
nmod |
site,drivers |
R2385 |
T3576 |
T3561 |
dobj |
degree,show |
R2386 |
T3710 |
T3709 |
punct |
-,site |
R2387 |
T3711 |
T3709 |
amod |
specific,site |
R2388 |
T3712 |
T3708 |
compound |
Cre,drivers |
R2389 |
T3577 |
T3576 |
prep |
of,degree |
R2390 |
T3713 |
T3681 |
punct |
.,offer |
R2391 |
T3578 |
T3579 |
amod |
wider,expression |
R2392 |
T3579 |
T3577 |
pobj |
expression,of |
R2393 |
T3580 |
T3579 |
punct |
“,expression |
R2394 |
T3581 |
T3579 |
amod |
ectopic,expression |
R2395 |
T3582 |
T3579 |
punct |
”,expression |
R2396 |
T3583 |
T3579 |
compound |
LACZ,expression |
R2397 |
T3584 |
T3579 |
punct |
", ",expression |