PMC:523229 / 15381-17005 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T3400 0-5 JJ denotes Other
T3401 6-11 NNS denotes sites
T3403 12-19 IN denotes besides
T3404 20-24 NN denotes limb
T3405 25-31 NNS denotes joints
T3406 32-36 RB denotes also
T3402 37-41 VBP denotes have
T3407 42-45 NN denotes Cre
T3409 45-46 HYPH denotes -
T3408 46-54 VBN denotes mediated
T3411 55-59 NN denotes lacZ
T3410 60-70 NN denotes expression
T3412 70-71 . denotes .
T3413 71-181 sentence denotes Starting at E13.5, LACZ activity is detected in an anterior and posterior domain of the limb bud (Figure 2C).
T3414 72-80 VBG denotes Starting
T3416 81-83 IN denotes at
T3417 84-89 NN denotes E13.5
T3418 89-91 , denotes ,
T3419 91-95 NN denotes LACZ
T3420 96-104 NN denotes activity
T3421 105-107 VBZ denotes is
T3415 108-116 VBN denotes detected
T3422 117-119 IN denotes in
T3423 120-122 DT denotes an
T3425 123-131 JJ denotes anterior
T3426 132-135 CC denotes and
T3427 136-145 JJ denotes posterior
T3424 146-152 NN denotes domain
T3428 153-155 IN denotes of
T3429 156-159 DT denotes the
T3431 160-164 NN denotes limb
T3430 165-168 NN denotes bud
T3432 169-170 -LRB- denotes (
T3433 170-176 NN denotes Figure
T3434 177-179 CD denotes 2C
T3435 179-180 -RRB- denotes )
T3436 180-181 . denotes .
T3437 181-363 sentence denotes At E14.5, LACZ activity is detectable in the developing ear pinnae, ribs, sternum, tissues in the face, and some regions of the brain and spinal cord (Figure 1B) (unpublished data).
T3438 182-184 IN denotes At
T3440 185-190 NN denotes E14.5
T3441 190-192 , denotes ,
T3442 192-196 NN denotes LACZ
T3443 197-205 NN denotes activity
T3439 206-208 VBZ denotes is
T3444 209-219 JJ denotes detectable
T3445 220-222 IN denotes in
T3446 223-226 DT denotes the
T3448 227-237 VBG denotes developing
T3449 238-241 NN denotes ear
T3447 242-248 NNS denotes pinnae
T3450 248-250 , denotes ,
T3451 250-254 NNS denotes ribs
T3452 254-256 , denotes ,
T3453 256-263 NN denotes sternum
T3454 263-265 , denotes ,
T3455 265-272 NNS denotes tissues
T3456 273-275 IN denotes in
T3457 276-279 DT denotes the
T3458 280-284 NN denotes face
T3459 284-286 , denotes ,
T3460 286-289 CC denotes and
T3461 290-294 DT denotes some
T3462 295-302 NNS denotes regions
T3463 303-305 IN denotes of
T3464 306-309 DT denotes the
T3465 310-315 NN denotes brain
T3466 316-319 CC denotes and
T3467 320-326 JJ denotes spinal
T3468 327-331 NN denotes cord
T3469 332-333 -LRB- denotes (
T3470 333-339 NN denotes Figure
T3471 340-342 CD denotes 1B
T3472 342-343 -RRB- denotes )
T3473 344-345 -LRB- denotes (
T3475 345-356 JJ denotes unpublished
T3474 357-361 NNS denotes data
T3476 361-362 -RRB- denotes )
T3477 362-363 . denotes .
T3478 363-545 sentence denotes At birth, LACZ is also expressed in tendons running along the vertebral column, regions of tendons in the wrist and ankle, and some tendon insertions (Figure 1D) (unpublished data).
T3479 364-366 IN denotes At
T3481 367-372 NN denotes birth
T3482 372-374 , denotes ,
T3483 374-378 NN denotes LACZ
T3484 379-381 VBZ denotes is
T3485 382-386 RB denotes also
T3480 387-396 VBN denotes expressed
T3486 397-399 IN denotes in
T3487 400-407 NNS denotes tendons
T3488 408-415 VBG denotes running
T3489 416-421 IN denotes along
T3490 422-425 DT denotes the
T3492 426-435 JJ denotes vertebral
T3491 436-442 NN denotes column
T3493 442-444 , denotes ,
T3494 444-451 NNS denotes regions
T3495 452-454 IN denotes of
T3496 455-462 NNS denotes tendons
T3497 463-465 IN denotes in
T3498 466-469 DT denotes the
T3499 470-475 NN denotes wrist
T3500 476-479 CC denotes and
T3501 480-485 NN denotes ankle
T3502 485-487 , denotes ,
T3503 487-490 CC denotes and
T3504 491-495 DT denotes some
T3506 496-502 NN denotes tendon
T3505 503-513 NNS denotes insertions
T3507 514-515 -LRB- denotes (
T3508 515-521 NN denotes Figure
T3509 522-524 CD denotes 1D
T3510 524-525 -RRB- denotes )
T3511 526-527 -LRB- denotes (
T3513 527-538 JJ denotes unpublished
T3512 539-543 NNS denotes data
T3514 543-544 -RRB- denotes )
T3515 544-545 . denotes .
T3516 545-734 sentence denotes By 5 wk of age, LACZ is also expressed in the hair follicles, ear cartilage, some cells in the growth plate of the long bones, and portions of the brain and spinal cord (unpublished data).
T3517 546-548 IN denotes By
T3519 549-550 CD denotes 5
T3520 551-553 NNS denotes wk
T3521 554-556 IN denotes of
T3522 557-560 NN denotes age
T3523 560-562 , denotes ,
T3524 562-566 NN denotes LACZ
T3525 567-569 VBZ denotes is
T3526 570-574 RB denotes also
T3518 575-584 VBN denotes expressed
T3527 585-587 IN denotes in
T3528 588-591 DT denotes the
T3530 592-596 NN denotes hair
T3529 597-606 NNS denotes follicles
T3531 606-608 , denotes ,
T3532 608-611 NN denotes ear
T3533 612-621 NN denotes cartilage
T3534 621-623 , denotes ,
T3535 623-627 DT denotes some
T3536 628-633 NNS denotes cells
T3537 634-636 IN denotes in
T3538 637-640 DT denotes the
T3540 641-647 NN denotes growth
T3539 648-653 NN denotes plate
T3541 654-656 IN denotes of
T3542 657-660 DT denotes the
T3544 661-665 JJ denotes long
T3543 666-671 NNS denotes bones
T3545 671-673 , denotes ,
T3546 673-676 CC denotes and
T3547 677-685 NNS denotes portions
T3548 686-688 IN denotes of
T3549 689-692 DT denotes the
T3550 693-698 NN denotes brain
T3551 699-702 CC denotes and
T3552 703-709 JJ denotes spinal
T3553 710-714 NN denotes cord
T3554 715-716 -LRB- denotes (
T3556 716-727 JJ denotes unpublished
T3555 728-732 NNS denotes data
T3557 732-733 -RRB- denotes )
T3558 733-734 . denotes .
T3559 734-917 sentence denotes Surprisingly, 23 of 63, or 37% of transgenic mice analyzed also show some degree of wider “ectopic” LACZ expression, which can extend throughout many different tissues in the animal.
T3560 735-747 RB denotes Surprisingly
T3562 747-749 , denotes ,
T3563 749-751 CD denotes 23
T3565 752-754 IN denotes of
T3564 755-757 CD denotes 63
T3566 757-759 , denotes ,
T3567 759-761 CC denotes or
T3568 762-764 CD denotes 37
T3569 764-765 NN denotes %
T3570 766-768 IN denotes of
T3571 769-779 JJ denotes transgenic
T3572 780-784 NNS denotes mice
T3573 785-793 VBN denotes analyzed
T3574 794-798 RB denotes also
T3561 799-803 VBP denotes show
T3575 804-808 DT denotes some
T3576 809-815 NN denotes degree
T3577 816-818 IN denotes of
T3578 819-824 JJR denotes wider
T3580 825-826 `` denotes
T3581 826-833 JJ denotes ectopic
T3582 833-834 '' denotes
T3583 835-839 NN denotes LACZ
T3579 840-850 NN denotes expression
T3584 850-852 , denotes ,
T3585 852-857 WDT denotes which
T3587 858-861 MD denotes can
T3586 862-868 VB denotes extend
T3588 869-879 IN denotes throughout
T3589 880-884 JJ denotes many
T3591 885-894 JJ denotes different
T3590 895-902 NNS denotes tissues
T3592 903-905 IN denotes in
T3593 906-909 DT denotes the
T3594 910-916 NN denotes animal
T3595 916-917 . denotes .
T3596 917-1151 sentence denotes However, sustained expression of the transgene itself, as assayed by HPLAP activity, is still restricted primarily to joints in animals that show evidence of more generalized recombination based on LACZ expression (unpublished data).
T3597 918-925 RB denotes However
T3599 925-927 , denotes ,
T3600 927-936 VBN denotes sustained
T3601 937-947 NN denotes expression
T3602 948-950 IN denotes of
T3603 951-954 DT denotes the
T3604 955-964 NN denotes transgene
T3605 965-971 PRP denotes itself
T3606 971-973 , denotes ,
T3607 973-975 IN denotes as
T3608 976-983 VBN denotes assayed
T3609 984-986 IN denotes by
T3610 987-992 NN denotes HPLAP
T3611 993-1001 NN denotes activity
T3612 1001-1003 , denotes ,
T3598 1003-1005 VBZ denotes is
T3613 1006-1011 RB denotes still
T3614 1012-1022 VBN denotes restricted
T3615 1023-1032 RB denotes primarily
T3616 1033-1035 IN denotes to
T3617 1036-1042 NNS denotes joints
T3618 1043-1045 IN denotes in
T3619 1046-1053 NNS denotes animals
T3620 1054-1058 WDT denotes that
T3621 1059-1063 VBP denotes show
T3622 1064-1072 NN denotes evidence
T3623 1073-1075 IN denotes of
T3624 1076-1080 RBR denotes more
T3625 1081-1092 VBN denotes generalized
T3626 1093-1106 NN denotes recombination
T3627 1107-1112 VBN denotes based
T3628 1113-1115 IN denotes on
T3629 1116-1120 NN denotes LACZ
T3630 1121-1131 NN denotes expression
T3631 1132-1133 -LRB- denotes (
T3633 1133-1144 JJ denotes unpublished
T3632 1145-1149 NNS denotes data
T3634 1149-1150 -RRB- denotes )
T3635 1150-1151 . denotes .
T3636 1151-1330 sentence denotes This suggests that in a fraction of animals, sporadic expression of Cre at some time early in development is sufficient to lead to both ectopic recombination and LACZ expression.
T3637 1152-1156 DT denotes This
T3638 1157-1165 VBZ denotes suggests
T3639 1166-1170 IN denotes that
T3641 1171-1173 IN denotes in
T3642 1174-1175 DT denotes a
T3643 1176-1184 NN denotes fraction
T3644 1185-1187 IN denotes of
T3645 1188-1195 NNS denotes animals
T3646 1195-1197 , denotes ,
T3647 1197-1205 JJ denotes sporadic
T3648 1206-1216 NN denotes expression
T3649 1217-1219 IN denotes of
T3650 1220-1223 NN denotes Cre
T3651 1224-1226 IN denotes at
T3652 1227-1231 DT denotes some
T3653 1232-1236 NN denotes time
T3654 1237-1242 RB denotes early
T3655 1243-1245 IN denotes in
T3656 1246-1257 NN denotes development
T3640 1258-1260 VBZ denotes is
T3657 1261-1271 JJ denotes sufficient
T3658 1272-1274 TO denotes to
T3659 1275-1279 VB denotes lead
T3660 1280-1282 IN denotes to
T3661 1283-1287 CC denotes both
T3663 1288-1295 JJ denotes ectopic
T3662 1296-1309 NN denotes recombination
T3664 1310-1313 CC denotes and
T3665 1314-1318 NN denotes LACZ
T3666 1319-1329 NN denotes expression
T3667 1329-1330 . denotes .
T3668 1330-1624 sentence denotes While the fraction of animals with broader recombination patterns must be tracked and accounted for during experiments, these animals offer the potential benefit of revealing additional new functions of target genes that could be subsequently studied with additional site-specific Cre drivers.
T3669 1331-1336 IN denotes While
T3671 1337-1340 DT denotes the
T3672 1341-1349 NN denotes fraction
T3673 1350-1352 IN denotes of
T3674 1353-1360 NNS denotes animals
T3675 1361-1365 IN denotes with
T3676 1366-1373 JJR denotes broader
T3678 1374-1387 NN denotes recombination
T3677 1388-1396 NNS denotes patterns
T3679 1397-1401 MD denotes must
T3680 1402-1404 VB denotes be
T3670 1405-1412 VBN denotes tracked
T3682 1413-1416 CC denotes and
T3683 1417-1426 VBN denotes accounted
T3684 1427-1430 IN denotes for
T3685 1431-1437 IN denotes during
T3686 1438-1449 NNS denotes experiments
T3687 1449-1451 , denotes ,
T3688 1451-1456 DT denotes these
T3689 1457-1464 NNS denotes animals
T3681 1465-1470 VBP denotes offer
T3690 1471-1474 DT denotes the
T3692 1475-1484 JJ denotes potential
T3691 1485-1492 NN denotes benefit
T3693 1493-1495 IN denotes of
T3694 1496-1505 VBG denotes revealing
T3695 1506-1516 JJ denotes additional
T3697 1517-1520 JJ denotes new
T3696 1521-1530 NNS denotes functions
T3698 1531-1533 IN denotes of
T3699 1534-1540 NN denotes target
T3700 1541-1546 NNS denotes genes
T3701 1547-1551 WDT denotes that
T3703 1552-1557 MD denotes could
T3704 1558-1560 VB denotes be
T3705 1561-1573 RB denotes subsequently
T3702 1574-1581 VBN denotes studied
T3706 1582-1586 IN denotes with
T3707 1587-1597 JJ denotes additional
T3709 1598-1602 NN denotes site
T3710 1602-1603 HYPH denotes -
T3711 1603-1611 JJ denotes specific
T3712 1612-1615 NN denotes Cre
T3708 1616-1623 NNS denotes drivers
T3713 1623-1624 . denotes .
R2075 T3479 T3480 prep At,expressed
R2076 T3481 T3479 pobj birth,At
R2077 T3482 T3480 punct ", ",expressed
R2078 T3483 T3480 nsubjpass LACZ,expressed
R2079 T3484 T3480 auxpass is,expressed
R2081 T3485 T3480 advmod also,expressed
R2083 T3486 T3480 prep in,expressed
R2089 T3487 T3486 pobj tendons,in
R2095 T3488 T3487 acl running,tendons
R2099 T3489 T3488 prep along,running
R2101 T3490 T3491 det the,column
R2102 T3491 T3489 pobj column,along
R2106 T3492 T3491 amod vertebral,column
R2109 T3493 T3487 punct ", ",tendons
R2113 T3494 T3487 conj regions,tendons
R2116 T3495 T3494 prep of,regions
R2117 T3400 T3401 amod Other,sites
R2118 T3496 T3495 pobj tendons,of
R2119 T3401 T3402 nsubj sites,have
R2120 T3497 T3494 prep in,regions
R2121 T3403 T3401 prep besides,sites
R2122 T3404 T3405 compound limb,joints
R2123 T3498 T3499 det the,wrist
R2124 T3405 T3403 pobj joints,besides
R2125 T3406 T3402 advmod also,have
R2126 T3407 T3408 npadvmod Cre,mediated
R2127 T3408 T3410 amod mediated,expression
R2128 T3499 T3497 pobj wrist,in
R2129 T3409 T3408 punct -,mediated
R2130 T3410 T3402 dobj expression,have
R2131 T3411 T3410 compound lacZ,expression
R2132 T3500 T3499 cc and,wrist
R2133 T3412 T3402 punct .,have
R2134 T3414 T3415 advcl Starting,detected
R2135 T3501 T3499 conj ankle,wrist
R2136 T3416 T3414 prep at,Starting
R2137 T3502 T3494 punct ", ",regions
R2138 T3417 T3416 pobj E13.5,at
R2139 T3418 T3415 punct ", ",detected
R2140 T3419 T3420 compound LACZ,activity
R2141 T3420 T3415 nsubjpass activity,detected
R2142 T3421 T3415 auxpass is,detected
R2143 T3422 T3415 prep in,detected
R2144 T3423 T3424 det an,domain
R2145 T3503 T3494 cc and,regions
R2146 T3424 T3422 pobj domain,in
R2147 T3425 T3424 amod anterior,domain
R2148 T3426 T3425 cc and,anterior
R2149 T3427 T3425 conj posterior,anterior
R2150 T3504 T3505 det some,insertions
R2151 T3428 T3424 prep of,domain
R2152 T3429 T3430 det the,bud
R2153 T3505 T3494 conj insertions,regions
R2154 T3430 T3428 pobj bud,of
R2155 T3431 T3430 compound limb,bud
R2156 T3432 T3433 punct (,Figure
R2157 T3506 T3505 compound tendon,insertions
R2158 T3433 T3415 parataxis Figure,detected
R2159 T3434 T3433 nummod 2C,Figure
R2160 T3435 T3433 punct ),Figure
R2161 T3507 T3508 punct (,Figure
R2162 T3436 T3415 punct .,detected
R2163 T3438 T3439 prep At,is
R2164 T3508 T3480 parataxis Figure,expressed
R2165 T3440 T3438 pobj E14.5,At
R2166 T3441 T3439 punct ", ",is
R2167 T3509 T3508 nummod 1D,Figure
R2168 T3442 T3443 compound LACZ,activity
R2169 T3443 T3439 nsubj activity,is
R2170 T3510 T3508 punct ),Figure
R2171 T3444 T3439 acomp detectable,is
R2172 T3445 T3439 prep in,is
R2173 T3446 T3447 det the,pinnae
R2174 T3511 T3512 punct (,data
R2175 T3447 T3445 pobj pinnae,in
R2176 T3448 T3447 amod developing,pinnae
R2177 T3449 T3447 compound ear,pinnae
R2178 T3512 T3480 meta data,expressed
R2179 T3450 T3447 punct ", ",pinnae
R2180 T3451 T3447 appos ribs,pinnae
R2181 T3513 T3512 amod unpublished,data
R2182 T3452 T3447 punct ", ",pinnae
R2183 T3453 T3447 appos sternum,pinnae
R2184 T3454 T3447 punct ", ",pinnae
R2185 T3514 T3512 punct ),data
R2186 T3455 T3447 appos tissues,pinnae
R2187 T3456 T3439 prep in,is
R2188 T3457 T3458 det the,face
R2189 T3515 T3480 punct .,expressed
R2190 T3458 T3456 pobj face,in
R2191 T3459 T3458 punct ", ",face
R2192 T3460 T3458 cc and,face
R2193 T3461 T3462 det some,regions
R2194 T3462 T3458 conj regions,face
R2195 T3463 T3462 prep of,regions
R2196 T3517 T3518 prep By,expressed
R2197 T3464 T3465 det the,brain
R2198 T3465 T3463 pobj brain,of
R2199 T3466 T3465 cc and,brain
R2200 T3467 T3468 amod spinal,cord
R2201 T3468 T3465 conj cord,brain
R2202 T3519 T3520 nummod 5,wk
R2203 T3469 T3470 punct (,Figure
R2204 T3470 T3439 parataxis Figure,is
R2205 T3471 T3470 nummod 1B,Figure
R2206 T3472 T3470 punct ),Figure
R2207 T3473 T3474 punct (,data
R2208 T3520 T3517 pobj wk,By
R2209 T3474 T3439 meta data,is
R2210 T3475 T3474 amod unpublished,data
R2211 T3521 T3520 prep of,wk
R2212 T3476 T3474 punct ),data
R2213 T3522 T3521 pobj age,of
R2214 T3477 T3439 punct .,is
R2215 T3523 T3518 punct ", ",expressed
R2216 T3524 T3518 nsubjpass LACZ,expressed
R2217 T3525 T3518 auxpass is,expressed
R2218 T3526 T3518 advmod also,expressed
R2219 T3527 T3518 prep in,expressed
R2220 T3528 T3529 det the,follicles
R2221 T3529 T3527 pobj follicles,in
R2222 T3530 T3529 compound hair,follicles
R2223 T3585 T3586 dep which,extend
R2224 T3531 T3529 punct ", ",follicles
R2225 T3586 T3579 relcl extend,expression
R2226 T3587 T3586 aux can,extend
R2227 T3588 T3586 prep throughout,extend
R2228 T3532 T3533 compound ear,cartilage
R2229 T3589 T3590 amod many,tissues
R2230 T3590 T3588 pobj tissues,throughout
R2231 T3591 T3590 amod different,tissues
R2232 T3533 T3529 appos cartilage,follicles
R2233 T3592 T3590 prep in,tissues
R2234 T3593 T3594 det the,animal
R2235 T3594 T3592 pobj animal,in
R2236 T3534 T3529 punct ", ",follicles
R2237 T3595 T3561 punct .,show
R2238 T3535 T3536 det some,cells
R2239 T3597 T3598 advmod However,is
R2240 T3599 T3598 punct ", ",is
R2241 T3536 T3529 conj cells,follicles
R2242 T3600 T3601 amod sustained,expression
R2243 T3601 T3598 nsubj expression,is
R2244 T3602 T3601 prep of,expression
R2245 T3603 T3604 det the,transgene
R2246 T3604 T3602 pobj transgene,of
R2247 T3605 T3604 appos itself,transgene
R2248 T3537 T3536 prep in,cells
R2249 T3606 T3598 punct ", ",is
R2250 T3607 T3608 mark as,assayed
R2251 T3608 T3598 advcl assayed,is
R2252 T3538 T3539 det the,plate
R2253 T3609 T3608 prep by,assayed
R2254 T3610 T3611 compound HPLAP,activity
R2255 T3611 T3609 pobj activity,by
R2256 T3539 T3537 pobj plate,in
R2257 T3612 T3598 punct ", ",is
R2258 T3613 T3598 advmod still,is
R2259 T3614 T3598 acomp restricted,is
R2260 T3540 T3539 compound growth,plate
R2261 T3615 T3616 advmod primarily,to
R2262 T3616 T3614 prep to,restricted
R2263 T3617 T3616 pobj joints,to
R2264 T3541 T3539 prep of,plate
R2265 T3618 T3617 prep in,joints
R2266 T3619 T3618 pobj animals,in
R2267 T3620 T3621 dep that,show
R2268 T3542 T3543 det the,bones
R2269 T3621 T3619 relcl show,animals
R2270 T3622 T3621 dobj evidence,show
R2271 T3623 T3622 prep of,evidence
R2272 T3543 T3541 pobj bones,of
R2273 T3624 T3625 advmod more,generalized
R2274 T3625 T3626 amod generalized,recombination
R2275 T3626 T3623 pobj recombination,of
R2276 T3544 T3543 amod long,bones
R2277 T3627 T3621 prep based,show
R2278 T3628 T3627 prep on,based
R2279 T3629 T3630 compound LACZ,expression
R2280 T3545 T3536 punct ", ",cells
R2281 T3630 T3628 pobj expression,on
R2282 T3631 T3632 punct (,data
R2283 T3632 T3598 meta data,is
R2284 T3546 T3536 cc and,cells
R2285 T3633 T3632 amod unpublished,data
R2286 T3634 T3632 punct ),data
R2287 T3635 T3598 punct .,is
R2288 T3547 T3536 conj portions,cells
R2289 T3637 T3638 nsubj This,suggests
R2290 T3548 T3547 prep of,portions
R2291 T3639 T3640 mark that,is
R2292 T3549 T3550 det the,brain
R2293 T3550 T3548 pobj brain,of
R2294 T3640 T3638 ccomp is,suggests
R2295 T3641 T3640 prep in,is
R2296 T3642 T3643 det a,fraction
R2297 T3643 T3641 pobj fraction,in
R2298 T3644 T3643 prep of,fraction
R2299 T3551 T3550 cc and,brain
R2300 T3645 T3644 pobj animals,of
R2301 T3646 T3640 punct ", ",is
R2302 T3647 T3648 amod sporadic,expression
R2303 T3552 T3553 amod spinal,cord
R2304 T3648 T3640 nsubj expression,is
R2305 T3649 T3648 prep of,expression
R2306 T3650 T3649 pobj Cre,of
R2307 T3553 T3550 conj cord,brain
R2308 T3651 T3648 prep at,expression
R2309 T3652 T3653 det some,time
R2310 T3653 T3651 pobj time,at
R2311 T3554 T3555 punct (,data
R2312 T3654 T3653 advmod early,time
R2313 T3655 T3654 prep in,early
R2314 T3656 T3655 pobj development,in
R2315 T3555 T3547 meta data,portions
R2316 T3657 T3640 acomp sufficient,is
R2317 T3658 T3659 aux to,lead
R2318 T3556 T3555 amod unpublished,data
R2319 T3659 T3657 xcomp lead,sufficient
R2320 T3660 T3659 prep to,lead
R2321 T3661 T3662 preconj both,recombination
R2322 T3557 T3555 punct ),data
R2323 T3662 T3660 pobj recombination,to
R2324 T3663 T3662 amod ectopic,recombination
R2325 T3664 T3662 cc and,recombination
R2326 T3558 T3518 punct .,expressed
R2327 T3665 T3666 compound LACZ,expression
R2328 T3666 T3662 conj expression,recombination
R2329 T3667 T3638 punct .,suggests
R2330 T3560 T3561 advmod Surprisingly,show
R2331 T3669 T3670 mark While,tracked
R2332 T3670 T3681 advcl tracked,offer
R2333 T3671 T3672 det the,fraction
R2334 T3562 T3561 punct ", ",show
R2335 T3672 T3670 nsubj fraction,tracked
R2336 T3673 T3672 prep of,fraction
R2337 T3674 T3673 pobj animals,of
R2338 T3563 T3564 quantmod 23,63
R2339 T3675 T3674 prep with,animals
R2340 T3676 T3677 amod broader,patterns
R2341 T3677 T3675 pobj patterns,with
R2342 T3564 T3561 nsubj 63,show
R2343 T3678 T3677 compound recombination,patterns
R2344 T3679 T3670 aux must,tracked
R2345 T3680 T3670 aux be,tracked
R2346 T3682 T3670 cc and,tracked
R2347 T3683 T3670 conj accounted,tracked
R2348 T3565 T3564 quantmod of,63
R2349 T3684 T3683 prep for,accounted
R2350 T3685 T3670 prep during,tracked
R2351 T3686 T3685 pobj experiments,during
R2352 T3566 T3564 punct ", ",63
R2353 T3687 T3681 punct ", ",offer
R2354 T3688 T3689 det these,animals
R2355 T3689 T3681 nsubj animals,offer
R2356 T3567 T3564 cc or,63
R2357 T3690 T3691 det the,benefit
R2358 T3568 T3569 nummod 37,%
R2359 T3569 T3564 conj %,63
R2360 T3691 T3681 dobj benefit,offer
R2361 T3570 T3564 prep of,63
R2362 T3692 T3691 amod potential,benefit
R2363 T3693 T3691 prep of,benefit
R2364 T3694 T3693 pcomp revealing,of
R2365 T3571 T3572 amod transgenic,mice
R2366 T3695 T3696 amod additional,functions
R2367 T3696 T3694 dobj functions,revealing
R2368 T3697 T3696 amod new,functions
R2369 T3572 T3570 pobj mice,of
R2370 T3698 T3696 prep of,functions
R2371 T3699 T3700 compound target,genes
R2372 T3700 T3698 pobj genes,of
R2373 T3573 T3572 acl analyzed,mice
R2374 T3701 T3702 dep that,studied
R2375 T3702 T3700 relcl studied,genes
R2376 T3703 T3702 aux could,studied
R2377 T3574 T3561 advmod also,show
R2378 T3704 T3702 auxpass be,studied
R2379 T3705 T3702 advmod subsequently,studied
R2380 T3706 T3702 prep with,studied
R2381 T3575 T3576 det some,degree
R2382 T3707 T3708 amod additional,drivers
R2383 T3708 T3706 pobj drivers,with
R2384 T3709 T3708 nmod site,drivers
R2385 T3576 T3561 dobj degree,show
R2386 T3710 T3709 punct -,site
R2387 T3711 T3709 amod specific,site
R2388 T3712 T3708 compound Cre,drivers
R2389 T3577 T3576 prep of,degree
R2390 T3713 T3681 punct .,offer
R2391 T3578 T3579 amod wider,expression
R2392 T3579 T3577 pobj expression,of
R2393 T3580 T3579 punct “,expression
R2394 T3581 T3579 amod ectopic,expression
R2395 T3582 T3579 punct ”,expression
R2396 T3583 T3579 compound LACZ,expression
R2397 T3584 T3579 punct ", ",expression