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PMC:516044 / 2026-2794 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T770 0-7 NNP denotes Pendred
T771 8-16 NN denotes syndrome
T772 17-19 VBZ denotes is
T773 20-21 DT denotes a
T775 22-32 RB denotes relatively
T776 33-39 JJ denotes common
T777 40-49 JJ denotes autosomal
T779 49-50 HYPH denotes -
T778 50-59 JJ denotes recessive
T774 60-68 NN denotes disorder
T780 69-82 VBN denotes characterized
T781 83-85 IN denotes by
T782 86-94 NN denotes deafness
T783 95-98 CC denotes and
T784 99-105 NN denotes goiter
T785 106-107 -LRB- denotes [
T786 107-108 CD denotes 1
T787 108-109 -RRB- denotes ]
T788 109-110 . denotes .
T789 110-212 sentence denotes The syndrome is caused by mutations of the PDS gene SLC26A4, which codes for the protein pendrin [2].
T790 111-114 DT denotes The
T791 115-123 NN denotes syndrome
T793 124-126 VBZ denotes is
T792 127-133 VBN denotes caused
T794 134-136 IN denotes by
T795 137-146 NNS denotes mutations
T796 147-149 IN denotes of
T797 150-153 DT denotes the
T799 154-157 NN denotes PDS
T798 158-162 NN denotes gene
T800 163-170 NN denotes SLC26A4
T801 170-172 , denotes ,
T802 172-177 WDT denotes which
T803 178-183 VBZ denotes codes
T804 184-187 IN denotes for
T805 188-191 DT denotes the
T807 192-199 NN denotes protein
T806 200-207 NN denotes pendrin
T808 208-209 -LRB- denotes [
T809 209-210 CD denotes 2
T810 210-211 -RRB- denotes ]
T811 211-212 . denotes .
T812 212-326 sentence denotes Deafness is congenital and generally profound although sometimes late in onset and provoked by light head injury.
T813 213-221 NN denotes Deafness
T814 222-224 VBZ denotes is
T815 225-235 JJ denotes congenital
T816 236-239 CC denotes and
T817 240-249 RB denotes generally
T818 250-258 JJ denotes profound
T819 259-267 IN denotes although
T821 268-277 RB denotes sometimes
T820 278-282 JJ denotes late
T822 283-285 IN denotes in
T823 286-291 NN denotes onset
T824 292-295 CC denotes and
T825 296-304 VBN denotes provoked
T826 305-307 IN denotes by
T827 308-313 JJ denotes light
T829 314-318 NN denotes head
T828 319-325 NN denotes injury
T830 325-326 . denotes .
T831 326-362 sentence denotes Vestibular dysfunction is uncommon.
T832 327-337 JJ denotes Vestibular
T833 338-349 NN denotes dysfunction
T834 350-352 VBZ denotes is
T835 353-361 JJ denotes uncommon
T836 361-362 . denotes .
T837 362-424 sentence denotes Goiter is variable and generally develops around puberty [3].
T838 363-369 NN denotes Goiter
T839 370-372 VBZ denotes is
T840 373-381 JJ denotes variable
T841 382-385 CC denotes and
T842 386-395 RB denotes generally
T843 396-404 VBZ denotes develops
T844 405-411 IN denotes around
T845 412-419 NN denotes puberty
T846 420-421 -LRB- denotes [
T847 421-422 CD denotes 3
T848 422-423 -RRB- denotes ]
T849 423-424 . denotes .
T850 424-623 sentence denotes The cause of goiter appears to be an impairment of iodide fixation in the follicular lumen due to a reduced rate of iodide transport across the apical membrane of thyroid gland epithelial cells [4].
T851 425-428 DT denotes The
T852 429-434 NN denotes cause
T854 435-437 IN denotes of
T855 438-444 NN denotes goiter
T853 445-452 VBZ denotes appears
T856 453-455 TO denotes to
T857 456-458 VB denotes be
T858 459-461 DT denotes an
T859 462-472 NN denotes impairment
T860 473-475 IN denotes of
T861 476-482 NN denotes iodide
T862 483-491 NN denotes fixation
T863 492-494 IN denotes in
T864 495-498 DT denotes the
T866 499-509 JJ denotes follicular
T865 510-515 NN denotes lumen
T867 516-519 IN denotes due
T868 520-522 IN denotes to
T869 523-524 DT denotes a
T871 525-532 VBN denotes reduced
T870 533-537 NN denotes rate
T872 538-540 IN denotes of
T873 541-547 NN denotes iodide
T874 548-557 NN denotes transport
T875 558-564 IN denotes across
T876 565-568 DT denotes the
T878 569-575 JJ denotes apical
T877 576-584 NN denotes membrane
T879 585-587 IN denotes of
T880 588-595 JJ denotes thyroid
T881 596-601 NN denotes gland
T883 602-612 JJ denotes epithelial
T882 613-618 NNS denotes cells
T884 619-620 -LRB- denotes [
T885 620-621 CD denotes 4
T886 621-622 -RRB- denotes ]
T887 622-623 . denotes .
T888 623-768 sentence denotes A positive perchlorate discharge test and an enlarged vestibular aqueduct appear to be the most reliable clinical signs of Pendred syndrome [5].
T889 624-625 DT denotes A
T891 626-634 JJ denotes positive
T892 635-646 NN denotes perchlorate
T893 647-656 NN denotes discharge
T890 657-661 NN denotes test
T895 662-665 CC denotes and
T896 666-668 DT denotes an
T898 669-677 VBN denotes enlarged
T899 678-688 JJ denotes vestibular
T897 689-697 NN denotes aqueduct
T894 698-704 VBP denotes appear
T900 705-707 TO denotes to
T901 708-710 VB denotes be
T902 711-714 DT denotes the
T904 715-719 RBS denotes most
T905 720-728 JJ denotes reliable
T906 729-737 JJ denotes clinical
T903 738-743 NNS denotes signs
T907 744-746 IN denotes of
T908 747-754 NNP denotes Pendred
T909 755-763 NN denotes syndrome
T910 764-765 -LRB- denotes [
T911 765-766 CD denotes 5
T912 766-767 -RRB- denotes ]
T913 767-768 . denotes .
R332 T770 T771 compound Pendred,syndrome
R333 T771 T772 nsubj syndrome,is
R334 T773 T774 det a,disorder
R335 T774 T772 attr disorder,is
R336 T775 T776 advmod relatively,common
R337 T776 T774 amod common,disorder
R338 T777 T778 amod autosomal,recessive
R339 T778 T774 amod recessive,disorder
R340 T779 T778 punct -,recessive
R341 T780 T774 acl characterized,disorder
R342 T781 T780 agent by,characterized
R343 T782 T781 pobj deafness,by
R344 T783 T782 cc and,deafness
R345 T784 T782 conj goiter,deafness
R346 T785 T786 punct [,1
R347 T786 T780 parataxis 1,characterized
R348 T787 T786 punct ],1
R349 T788 T772 punct .,is
R350 T790 T791 det The,syndrome
R351 T791 T792 nsubjpass syndrome,caused
R352 T793 T792 auxpass is,caused
R353 T794 T792 agent by,caused
R354 T795 T794 pobj mutations,by
R355 T796 T795 prep of,mutations
R356 T797 T798 det the,gene
R357 T798 T796 pobj gene,of
R358 T799 T798 compound PDS,gene
R359 T800 T798 appos SLC26A4,gene
R360 T801 T798 punct ", ",gene
R361 T802 T803 dep which,codes
R362 T803 T798 relcl codes,gene
R363 T804 T803 prep for,codes
R364 T805 T806 det the,pendrin
R365 T806 T804 pobj pendrin,for
R366 T807 T806 compound protein,pendrin
R367 T808 T809 punct [,2
R368 T809 T803 parataxis 2,codes
R369 T810 T809 punct ],2
R370 T811 T792 punct .,caused
R371 T813 T814 nsubj Deafness,is
R372 T815 T814 acomp congenital,is
R373 T816 T815 cc and,congenital
R374 T817 T818 advmod generally,profound
R375 T818 T815 conj profound,congenital
R376 T819 T820 mark although,late
R377 T820 T818 advcl late,profound
R378 T821 T820 advmod sometimes,late
R379 T822 T820 prep in,late
R380 T823 T822 pobj onset,in
R381 T824 T815 cc and,congenital
R382 T825 T815 conj provoked,congenital
R383 T826 T825 agent by,provoked
R384 T827 T828 amod light,injury
R385 T828 T826 pobj injury,by
R386 T829 T828 compound head,injury
R387 T830 T814 punct .,is
R388 T832 T833 amod Vestibular,dysfunction
R389 T833 T834 nsubj dysfunction,is
R390 T835 T834 acomp uncommon,is
R391 T836 T834 punct .,is
R392 T838 T839 nsubj Goiter,is
R393 T840 T839 acomp variable,is
R394 T841 T839 cc and,is
R395 T842 T843 advmod generally,develops
R396 T843 T839 conj develops,is
R397 T844 T843 prep around,develops
R398 T845 T844 pobj puberty,around
R399 T846 T847 punct [,3
R400 T847 T843 parataxis 3,develops
R401 T848 T847 punct ],3
R402 T849 T839 punct .,is
R403 T851 T852 det The,cause
R404 T852 T853 nsubj cause,appears
R405 T854 T852 prep of,cause
R406 T855 T854 pobj goiter,of
R407 T856 T857 aux to,be
R408 T857 T853 xcomp be,appears
R409 T858 T859 det an,impairment
R410 T859 T857 attr impairment,be
R411 T860 T859 prep of,impairment
R412 T861 T862 compound iodide,fixation
R413 T862 T860 pobj fixation,of
R414 T863 T859 prep in,impairment
R415 T864 T865 det the,lumen
R416 T865 T863 pobj lumen,in
R417 T866 T865 amod follicular,lumen
R418 T867 T857 prep due,be
R419 T868 T867 pcomp to,due
R420 T869 T870 det a,rate
R421 T870 T867 pobj rate,due
R422 T871 T870 amod reduced,rate
R423 T872 T870 prep of,rate
R424 T873 T874 compound iodide,transport
R425 T874 T872 pobj transport,of
R426 T875 T874 prep across,transport
R427 T876 T877 det the,membrane
R428 T877 T875 pobj membrane,across
R429 T878 T877 amod apical,membrane
R430 T879 T877 prep of,membrane
R431 T880 T881 amod thyroid,gland
R432 T881 T882 nmod gland,cells
R433 T882 T879 pobj cells,of
R434 T883 T882 amod epithelial,cells
R435 T884 T885 punct [,4
R436 T885 T857 parataxis 4,be
R437 T886 T885 punct ],4
R438 T887 T853 punct .,appears
R439 T889 T890 det A,test
R440 T890 T894 nsubj test,appear
R441 T891 T890 amod positive,test
R442 T892 T893 compound perchlorate,discharge
R443 T893 T890 compound discharge,test
R444 T895 T890 cc and,test
R445 T896 T897 det an,aqueduct
R446 T897 T890 conj aqueduct,test
R447 T898 T897 amod enlarged,aqueduct
R448 T899 T897 amod vestibular,aqueduct
R449 T900 T901 aux to,be
R450 T901 T894 xcomp be,appear
R451 T902 T903 det the,signs
R452 T903 T901 attr signs,be
R453 T904 T905 advmod most,reliable
R454 T905 T903 amod reliable,signs
R455 T906 T903 amod clinical,signs
R456 T907 T903 prep of,signs
R457 T908 T909 compound Pendred,syndrome
R458 T909 T907 pobj syndrome,of
R459 T910 T911 punct [,5
R460 T911 T901 parataxis 5,be
R461 T912 T911 punct ],5
R462 T913 T894 punct .,appear