PMC:509410 / 9724-10852 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T5034 10-20 NN denotes Activation
T5036 21-23 IN denotes of
T5037 24-29 NN denotes PPARδ
T5035 30-37 VBZ denotes Induces
T5038 38-43 NNS denotes Genes
T5039 44-51 JJ denotes Typical
T5040 52-55 IN denotes for
T5041 56-60 NN denotes Type
T5043 61-62 CD denotes I
T5042 63-69 NNS denotes Fibers
T5044 70-73 CC denotes and
T5045 74-82 VBZ denotes Promotes
T5046 83-96 JJ denotes Mitochondrial
T5047 97-107 NN denotes Biogenesis
T5048 107-253 sentence denotes (A) Total RNA (10 μg/lane) prepared from gastrocnemius muscle of transgenic (TG) and wild-type (WT) littermates was probed with indicated probes.
T5049 108-109 -LRB- denotes (
T5050 109-110 LS denotes A
T5052 110-111 -RRB- denotes )
T5053 112-117 JJ denotes Total
T5054 118-121 NN denotes RNA
T5055 122-123 -LRB- denotes (
T5057 123-125 CD denotes 10
T5056 126-128 NNS denotes μg
T5058 128-129 SYM denotes /
T5059 129-133 NN denotes lane
T5060 133-134 -RRB- denotes )
T5061 135-143 VBN denotes prepared
T5062 144-148 IN denotes from
T5063 149-162 NN denotes gastrocnemius
T5064 163-169 NN denotes muscle
T5065 170-172 IN denotes of
T5066 173-183 JJ denotes transgenic
T5068 184-185 -LRB- denotes (
T5069 185-187 JJ denotes TG
T5070 187-188 -RRB- denotes )
T5071 189-192 CC denotes and
T5072 193-197 JJ denotes wild
T5074 197-198 HYPH denotes -
T5073 198-202 NN denotes type
T5075 203-204 -LRB- denotes (
T5076 204-206 NN denotes WT
T5077 206-207 -RRB- denotes )
T5067 208-219 NNS denotes littermates
T5078 220-223 VBD denotes was
T5051 224-230 VBN denotes probed
T5079 231-235 IN denotes with
T5080 236-245 VBN denotes indicated
T5081 246-252 NNS denotes probes
T5082 252-253 . denotes .
T5083 253-307 sentence denotes The fold increase of induction of each gene is shown.
T5084 254-257 DT denotes The
T5086 258-262 JJ denotes fold
T5085 263-271 NN denotes increase
T5088 272-274 IN denotes of
T5089 275-284 NN denotes induction
T5090 285-287 IN denotes of
T5091 288-292 DT denotes each
T5092 293-297 NN denotes gene
T5093 298-300 VBZ denotes is
T5087 301-306 VBN denotes shown
T5094 306-307 . denotes .
T5095 307-524 sentence denotes (B) Total genomic DNA (10 μg/lane) prepared from gastrocnemius muscle was digested with Nco1 and subjected to Southern analysis with COXII (mitochondrial genome–encoded) and MCIP1 (nuclear genome–encoded) DNA probes.
T5096 308-309 -LRB- denotes (
T5097 309-310 LS denotes B
T5099 310-311 -RRB- denotes )
T5100 312-317 JJ denotes Total
T5102 318-325 JJ denotes genomic
T5101 326-329 NN denotes DNA
T5103 330-331 -LRB- denotes (
T5105 331-333 CD denotes 10
T5104 334-336 NNS denotes μg
T5106 336-337 SYM denotes /
T5107 337-341 NN denotes lane
T5108 341-342 -RRB- denotes )
T5109 343-351 VBN denotes prepared
T5110 352-356 IN denotes from
T5111 357-370 NN denotes gastrocnemius
T5112 371-377 NN denotes muscle
T5113 378-381 VBD denotes was
T5098 382-390 VBN denotes digested
T5114 391-395 IN denotes with
T5115 396-400 NN denotes Nco1
T5116 401-404 CC denotes and
T5117 405-414 VBN denotes subjected
T5118 415-417 IN denotes to
T5119 418-426 NNP denotes Southern
T5120 427-435 NN denotes analysis
T5121 436-440 IN denotes with
T5122 441-446 NN denotes COXII
T5124 447-448 -LRB- denotes (
T5126 448-461 JJ denotes mitochondrial
T5127 462-468 NN denotes genome
T5128 468-469 HYPH denotes
T5125 469-476 VBN denotes encoded
T5129 476-477 -RRB- denotes )
T5130 478-481 CC denotes and
T5131 482-487 NN denotes MCIP1
T5132 488-489 -LRB- denotes (
T5134 489-496 JJ denotes nuclear
T5135 497-503 NN denotes genome
T5136 503-504 HYPH denotes
T5133 504-511 VBN denotes encoded
T5137 511-512 -RRB- denotes )
T5138 513-516 NN denotes DNA
T5123 517-523 NNS denotes probes
T5139 523-524 . denotes .
T5140 524-632 sentence denotes (C) Equal amounts of gastrocnemius muscle were collected from both transgenic mice and control littermates.
T5141 525-526 -LRB- denotes (
T5142 526-527 LS denotes C
T5144 527-528 -RRB- denotes )
T5145 529-534 JJ denotes Equal
T5146 535-542 NNS denotes amounts
T5147 543-545 IN denotes of
T5148 546-559 NN denotes gastrocnemius
T5149 560-566 NN denotes muscle
T5150 567-571 VBD denotes were
T5143 572-581 VBN denotes collected
T5151 582-586 IN denotes from
T5152 587-591 CC denotes both
T5154 592-602 JJ denotes transgenic
T5153 603-607 NNS denotes mice
T5155 608-611 CC denotes and
T5156 612-619 NN denotes control
T5157 620-631 NNS denotes littermates
T5158 631-632 . denotes .
T5159 632-702 sentence denotes Total mitochondrial DNA was isolated and separated on 1% agarose gel.
T5160 633-638 JJ denotes Total
T5162 639-652 JJ denotes mitochondrial
T5161 653-656 NN denotes DNA
T5164 657-660 VBD denotes was
T5163 661-669 VBN denotes isolated
T5165 670-673 CC denotes and
T5166 674-683 VBN denotes separated
T5167 684-686 IN denotes on
T5168 687-688 CD denotes 1
T5169 688-689 NN denotes %
T5171 690-697 NN denotes agarose
T5170 698-701 NN denotes gel
T5172 701-702 . denotes .
T5173 702-793 sentence denotes The relative abundance of mitochondrial DNA in transgenic and wild-type mice is presented.
T5174 703-706 DT denotes The
T5176 707-715 JJ denotes relative
T5175 716-725 NN denotes abundance
T5178 726-728 IN denotes of
T5179 729-742 JJ denotes mitochondrial
T5180 743-746 NN denotes DNA
T5181 747-749 IN denotes in
T5182 750-760 JJ denotes transgenic
T5184 761-764 CC denotes and
T5185 765-769 JJ denotes wild
T5187 769-770 HYPH denotes -
T5186 770-774 NN denotes type
T5183 775-779 NNS denotes mice
T5188 780-782 VBZ denotes is
T5177 783-792 VBN denotes presented
T5189 792-793 . denotes .
T5190 793-873 sentence denotes (D) Western blot analysis of muscle fiber markers and mitochondrial components.
T5191 794-795 -LRB- denotes (
T5192 795-796 LS denotes D
T5194 796-797 -RRB- denotes )
T5195 798-805 NNP denotes Western
T5196 806-810 NN denotes blot
T5193 811-819 NN denotes analysis
T5197 820-822 IN denotes of
T5198 823-829 NN denotes muscle
T5199 830-835 NN denotes fiber
T5200 836-843 NNS denotes markers
T5201 844-847 CC denotes and
T5202 848-861 JJ denotes mitochondrial
T5203 862-872 NNS denotes components
T5204 872-873 . denotes .
T5205 873-945 sentence denotes Each lane was loaded with 80 μg of total gastrocnemius muscle extracts.
T5206 874-878 DT denotes Each
T5207 879-883 NN denotes lane
T5209 884-887 VBD denotes was
T5208 888-894 VBN denotes loaded
T5210 895-899 IN denotes with
T5211 900-902 CD denotes 80
T5212 903-905 NNS denotes μg
T5213 906-908 IN denotes of
T5214 909-914 JJ denotes total
T5216 915-928 NN denotes gastrocnemius
T5217 929-935 NN denotes muscle
T5215 936-944 NNS denotes extracts
T5218 944-945 . denotes .
T5219 945-1032 sentence denotes (E) Wild-type C57B6 mice were treated with vehicle or PPARδ agonist GW501516 for 10 d.
T5220 946-947 -LRB- denotes (
T5221 947-948 LS denotes E
T5223 948-949 -RRB- denotes )
T5224 950-954 JJ denotes Wild
T5226 954-955 HYPH denotes -
T5225 955-959 NN denotes type
T5228 960-965 NN denotes C57B6
T5227 966-970 NNS denotes mice
T5229 971-975 VBD denotes were
T5222 976-983 VBN denotes treated
T5230 984-988 IN denotes with
T5231 989-996 NN denotes vehicle
T5232 997-999 CC denotes or
T5233 1000-1005 NN denotes PPARδ
T5234 1006-1013 NN denotes agonist
T5235 1014-1022 NN denotes GW501516
T5236 1023-1026 IN denotes for
T5237 1027-1029 CD denotes 10
T5238 1030-1031 NN denotes d
T5239 1031-1032 . denotes .
T5240 1032-1128 sentence denotes Total RNA (10 μg/lane) prepared from the gastrocnemius muscle was probed with indicated probes.
T5241 1033-1038 JJ denotes Total
T5242 1039-1042 NN denotes RNA
T5244 1043-1044 -LRB- denotes (
T5246 1044-1046 CD denotes 10
T5245 1047-1049 NNS denotes μg
T5247 1049-1050 SYM denotes /
T5248 1050-1054 NN denotes lane
T5249 1054-1055 -RRB- denotes )
T5250 1056-1064 VBN denotes prepared
T5251 1065-1069 IN denotes from
T5252 1070-1073 DT denotes the
T5254 1074-1087 NN denotes gastrocnemius
T5253 1088-1094 NN denotes muscle
T5255 1095-1098 VBD denotes was
T5243 1099-1105 VBN denotes probed
T5256 1106-1110 IN denotes with
T5257 1111-1120 VBN denotes indicated
T5258 1121-1127 NNS denotes probes
T5259 1127-1128 . denotes .
R3586 T5034 T5035 nsubj Activation,Induces
R3587 T5036 T5034 prep of,Activation
R3588 T5037 T5036 pobj PPARδ,of
R3589 T5038 T5035 dobj Genes,Induces
R3590 T5039 T5038 amod Typical,Genes
R3591 T5040 T5039 prep for,Typical
R3592 T5041 T5042 nmod Type,Fibers
R3593 T5042 T5040 pobj Fibers,for
R3594 T5043 T5041 nummod I,Type
R3595 T5044 T5035 cc and,Induces
R3596 T5045 T5035 conj Promotes,Induces
R3597 T5046 T5047 amod Mitochondrial,Biogenesis
R3598 T5047 T5045 dobj Biogenesis,Promotes
R3599 T5049 T5050 punct (,A
R3600 T5050 T5051 meta A,probed
R3601 T5052 T5050 punct ),A
R3602 T5053 T5054 amod Total,RNA
R3603 T5054 T5051 nsubjpass RNA,probed
R3604 T5055 T5056 punct (,μg
R3605 T5056 T5054 parataxis μg,RNA
R3606 T5057 T5056 nummod 10,μg
R3607 T5058 T5059 punct /,lane
R3608 T5059 T5056 prep lane,μg
R3609 T5060 T5056 punct ),μg
R3610 T5061 T5054 acl prepared,RNA
R3611 T5062 T5061 prep from,prepared
R3612 T5063 T5064 compound gastrocnemius,muscle
R3613 T5064 T5062 pobj muscle,from
R3614 T5065 T5064 prep of,muscle
R3615 T5066 T5067 amod transgenic,littermates
R3616 T5067 T5065 pobj littermates,of
R3617 T5068 T5069 punct (,TG
R3618 T5069 T5066 parataxis TG,transgenic
R3619 T5070 T5069 punct ),TG
R3620 T5071 T5066 cc and,transgenic
R3621 T5072 T5073 amod wild,type
R3622 T5073 T5066 conj type,transgenic
R3623 T5074 T5073 punct -,type
R3624 T5075 T5076 punct (,WT
R3625 T5076 T5073 parataxis WT,type
R3626 T5077 T5076 punct ),WT
R3627 T5078 T5051 auxpass was,probed
R3628 T5079 T5051 prep with,probed
R3629 T5080 T5081 amod indicated,probes
R3630 T5081 T5079 pobj probes,with
R3631 T5082 T5051 punct .,probed
R3632 T5084 T5085 det The,increase
R3633 T5085 T5087 nsubjpass increase,shown
R3634 T5086 T5085 amod fold,increase
R3635 T5088 T5085 prep of,increase
R3636 T5089 T5088 pobj induction,of
R3637 T5090 T5089 prep of,induction
R3638 T5091 T5092 det each,gene
R3639 T5092 T5090 pobj gene,of
R3640 T5093 T5087 auxpass is,shown
R3641 T5094 T5087 punct .,shown
R3642 T5096 T5097 punct (,B
R3643 T5097 T5098 meta B,digested
R3644 T5099 T5097 punct ),B
R3645 T5100 T5101 amod Total,DNA
R3646 T5101 T5098 nsubjpass DNA,digested
R3647 T5102 T5101 amod genomic,DNA
R3648 T5103 T5104 punct (,μg
R3649 T5104 T5101 parataxis μg,DNA
R3650 T5105 T5104 nummod 10,μg
R3651 T5106 T5107 punct /,lane
R3652 T5107 T5104 prep lane,μg
R3653 T5108 T5104 punct ),μg
R3654 T5109 T5101 acl prepared,DNA
R3655 T5110 T5109 prep from,prepared
R3656 T5111 T5112 compound gastrocnemius,muscle
R3657 T5112 T5110 pobj muscle,from
R3658 T5113 T5098 auxpass was,digested
R3659 T5114 T5098 prep with,digested
R3660 T5115 T5114 pobj Nco1,with
R3661 T5116 T5098 cc and,digested
R3662 T5117 T5098 conj subjected,digested
R3663 T5118 T5117 prep to,subjected
R3664 T5119 T5120 compound Southern,analysis
R3665 T5120 T5118 pobj analysis,to
R3666 T5121 T5117 prep with,subjected
R3667 T5122 T5123 nmod COXII,probes
R3668 T5123 T5121 pobj probes,with
R3669 T5124 T5125 punct (,encoded
R3670 T5125 T5122 parataxis encoded,COXII
R3671 T5126 T5127 amod mitochondrial,genome
R3672 T5127 T5125 npadvmod genome,encoded
R3673 T5128 T5125 punct –,encoded
R3674 T5129 T5125 punct ),encoded
R3675 T5130 T5122 cc and,COXII
R3676 T5131 T5122 conj MCIP1,COXII
R3677 T5132 T5133 punct (,encoded
R3678 T5133 T5131 parataxis encoded,MCIP1
R3679 T5134 T5135 amod nuclear,genome
R3680 T5135 T5133 npadvmod genome,encoded
R3681 T5136 T5133 punct –,encoded
R3682 T5137 T5133 punct ),encoded
R3683 T5138 T5123 compound DNA,probes
R3684 T5139 T5098 punct .,digested
R3685 T5141 T5142 punct (,C
R3686 T5142 T5143 meta C,collected
R3687 T5144 T5142 punct ),C
R3688 T5145 T5146 amod Equal,amounts
R3689 T5146 T5143 nsubjpass amounts,collected
R3690 T5147 T5146 prep of,amounts
R3691 T5148 T5149 compound gastrocnemius,muscle
R3692 T5149 T5147 pobj muscle,of
R3693 T5150 T5143 auxpass were,collected
R3694 T5151 T5143 prep from,collected
R3695 T5152 T5153 preconj both,mice
R3696 T5153 T5151 pobj mice,from
R3697 T5154 T5153 amod transgenic,mice
R3698 T5155 T5153 cc and,mice
R3699 T5156 T5157 compound control,littermates
R3700 T5157 T5153 conj littermates,mice
R3701 T5158 T5143 punct .,collected
R3702 T5160 T5161 amod Total,DNA
R3703 T5161 T5163 nsubjpass DNA,isolated
R3704 T5162 T5161 amod mitochondrial,DNA
R3705 T5164 T5163 auxpass was,isolated
R3706 T5165 T5163 cc and,isolated
R3707 T5166 T5163 conj separated,isolated
R3708 T5167 T5166 prep on,separated
R3709 T5168 T5169 nummod 1,%
R3710 T5169 T5170 compound %,gel
R3711 T5170 T5167 pobj gel,on
R3712 T5171 T5170 compound agarose,gel
R3713 T5172 T5163 punct .,isolated
R3714 T5174 T5175 det The,abundance
R3715 T5175 T5177 nsubjpass abundance,presented
R3716 T5176 T5175 amod relative,abundance
R3717 T5178 T5175 prep of,abundance
R3718 T5179 T5180 amod mitochondrial,DNA
R3719 T5180 T5178 pobj DNA,of
R3720 T5181 T5175 prep in,abundance
R3721 T5182 T5183 amod transgenic,mice
R3722 T5183 T5181 pobj mice,in
R3723 T5184 T5182 cc and,transgenic
R3724 T5185 T5186 amod wild,type
R3725 T5186 T5182 conj type,transgenic
R3726 T5187 T5186 punct -,type
R3727 T5188 T5177 auxpass is,presented
R3728 T5189 T5177 punct .,presented
R3729 T5191 T5192 punct (,D
R3730 T5192 T5193 meta D,analysis
R3731 T5194 T5192 punct ),D
R3732 T5195 T5196 compound Western,blot
R3733 T5196 T5193 compound blot,analysis
R3734 T5197 T5193 prep of,analysis
R3735 T5198 T5199 compound muscle,fiber
R3736 T5199 T5200 compound fiber,markers
R3737 T5200 T5197 pobj markers,of
R3738 T5201 T5200 cc and,markers
R3739 T5202 T5203 amod mitochondrial,components
R3740 T5203 T5200 conj components,markers
R3741 T5204 T5193 punct .,analysis
R3742 T5206 T5207 det Each,lane
R3743 T5207 T5208 nsubjpass lane,loaded
R3744 T5209 T5208 auxpass was,loaded
R3745 T5210 T5208 prep with,loaded
R3746 T5211 T5212 nummod 80,μg
R3747 T5212 T5210 pobj μg,with
R3748 T5213 T5212 prep of,μg
R3749 T5214 T5215 amod total,extracts
R3750 T5215 T5213 pobj extracts,of
R3751 T5216 T5217 compound gastrocnemius,muscle
R3752 T5217 T5215 compound muscle,extracts
R3753 T5218 T5208 punct .,loaded
R3754 T5220 T5221 punct (,E
R3755 T5221 T5222 meta E,treated
R3756 T5223 T5221 punct ),E
R3757 T5224 T5225 amod Wild,type
R3758 T5225 T5227 compound type,mice
R3759 T5226 T5225 punct -,type
R3760 T5227 T5222 nsubjpass mice,treated
R3761 T5228 T5227 compound C57B6,mice
R3762 T5229 T5222 auxpass were,treated
R3763 T5230 T5222 prep with,treated
R3764 T5231 T5230 pobj vehicle,with
R3765 T5232 T5231 cc or,vehicle
R3766 T5233 T5234 compound PPARδ,agonist
R3767 T5234 T5235 compound agonist,GW501516
R3768 T5235 T5231 conj GW501516,vehicle
R3769 T5236 T5222 prep for,treated
R3770 T5237 T5238 nummod 10,d
R3771 T5238 T5236 pobj d,for
R3772 T5239 T5222 punct .,treated
R3773 T5241 T5242 amod Total,RNA
R3774 T5242 T5243 nsubjpass RNA,probed
R3775 T5244 T5245 punct (,μg
R3776 T5245 T5242 parataxis μg,RNA
R3777 T5246 T5245 nummod 10,μg
R3778 T5247 T5248 punct /,lane
R3779 T5248 T5245 prep lane,μg
R3780 T5249 T5245 punct ),μg
R3781 T5250 T5242 acl prepared,RNA
R3782 T5251 T5250 prep from,prepared
R3783 T5252 T5253 det the,muscle
R3784 T5253 T5251 pobj muscle,from
R3785 T5254 T5253 compound gastrocnemius,muscle
R3786 T5255 T5243 auxpass was,probed
R3787 T5256 T5243 prep with,probed
R3788 T5257 T5258 amod indicated,probes
R3789 T5258 T5256 pobj probes,with
R3790 T5259 T5243 punct .,probed