| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T864 |
0-2 |
PRP |
denotes |
We |
| T866 |
3-7 |
VBP |
denotes |
have |
| T867 |
8-18 |
RB |
denotes |
previously |
| T865 |
19-30 |
VBN |
denotes |
established |
| T868 |
31-35 |
IN |
denotes |
that |
| T870 |
36-46 |
NN |
denotes |
peroxisome |
| T871 |
47-59 |
NN |
denotes |
proliferator |
| T873 |
59-60 |
HYPH |
denotes |
- |
| T872 |
60-69 |
VBN |
denotes |
activated |
| T874 |
70-78 |
NN |
denotes |
receptor |
| T875 |
79-80 |
-LRB- |
denotes |
( |
| T876 |
80-84 |
NN |
denotes |
PPAR |
| T877 |
84-85 |
-RRB- |
denotes |
) |
| T878 |
86-87 |
SYM |
denotes |
δ |
| T869 |
88-90 |
VBZ |
denotes |
is |
| T879 |
91-92 |
DT |
denotes |
a |
| T881 |
93-98 |
JJ |
denotes |
major |
| T882 |
99-114 |
JJ |
denotes |
transcriptional |
| T880 |
115-124 |
NN |
denotes |
regulator |
| T883 |
125-127 |
IN |
denotes |
of |
| T884 |
128-131 |
NN |
denotes |
fat |
| T885 |
132-139 |
NN |
denotes |
burning |
| T886 |
140-142 |
IN |
denotes |
in |
| T887 |
143-150 |
NN |
denotes |
adipose |
| T888 |
151-157 |
NN |
denotes |
tissue |
| T889 |
158-165 |
IN |
denotes |
through |
| T890 |
166-176 |
NN |
denotes |
activation |
| T891 |
177-179 |
IN |
denotes |
of |
| T892 |
180-187 |
NNS |
denotes |
enzymes |
| T893 |
188-198 |
VBN |
denotes |
associated |
| T894 |
199-203 |
IN |
denotes |
with |
| T895 |
204-208 |
JJ |
denotes |
long |
| T897 |
208-209 |
HYPH |
denotes |
- |
| T896 |
209-214 |
NN |
denotes |
chain |
| T899 |
215-220 |
JJ |
denotes |
fatty |
| T901 |
220-221 |
HYPH |
denotes |
- |
| T900 |
221-225 |
NN |
denotes |
acid |
| T902 |
226-227 |
NN |
denotes |
β |
| T903 |
227-228 |
HYPH |
denotes |
- |
| T898 |
228-237 |
NN |
denotes |
oxidation |
| T904 |
238-239 |
-LRB- |
denotes |
( |
| T905 |
239-243 |
NNP |
denotes |
Wang |
| T906 |
244-246 |
FW |
denotes |
et |
| T907 |
247-250 |
FW |
denotes |
al. |
| T908 |
251-255 |
CD |
denotes |
2003 |
| T909 |
255-256 |
-RRB- |
denotes |
) |
| T910 |
256-257 |
. |
denotes |
. |
| T911 |
257-378 |
sentence |
denotes |
Although PPARδ is the predominant PPAR isoform present in skeletal muscle, its in vivo function has not been determined. |
| T912 |
258-266 |
IN |
denotes |
Although |
| T914 |
267-272 |
NN |
denotes |
PPARδ |
| T913 |
273-275 |
VBZ |
denotes |
is |
| T916 |
276-279 |
DT |
denotes |
the |
| T918 |
280-291 |
JJ |
denotes |
predominant |
| T919 |
292-296 |
NN |
denotes |
PPAR |
| T917 |
297-304 |
NN |
denotes |
isoform |
| T920 |
305-312 |
JJ |
denotes |
present |
| T921 |
313-315 |
IN |
denotes |
in |
| T922 |
316-324 |
JJ |
denotes |
skeletal |
| T923 |
325-331 |
NN |
denotes |
muscle |
| T924 |
331-333 |
, |
denotes |
, |
| T925 |
333-336 |
PRP$ |
denotes |
its |
| T927 |
337-339 |
FW |
denotes |
in |
| T928 |
340-344 |
FW |
denotes |
vivo |
| T926 |
345-353 |
NN |
denotes |
function |
| T929 |
354-357 |
VBZ |
denotes |
has |
| T930 |
358-361 |
RB |
denotes |
not |
| T931 |
362-366 |
VBN |
denotes |
been |
| T915 |
367-377 |
VBN |
denotes |
determined |
| T932 |
377-378 |
. |
denotes |
. |
| T933 |
378-632 |
sentence |
denotes |
Our current study uncovers PPARδ as the first transcription factor able to drive the formation of functional type I muscle fibers, whose activation entrains complex pathways both enhancing physical performance and creating a state of obesity resistance. |
| T934 |
379-382 |
PRP$ |
denotes |
Our |
| T936 |
383-390 |
JJ |
denotes |
current |
| T935 |
391-396 |
NN |
denotes |
study |
| T937 |
397-405 |
VBZ |
denotes |
uncovers |
| T938 |
406-411 |
NN |
denotes |
PPARδ |
| T939 |
412-414 |
IN |
denotes |
as |
| T940 |
415-418 |
DT |
denotes |
the |
| T942 |
419-424 |
JJ |
denotes |
first |
| T943 |
425-438 |
NN |
denotes |
transcription |
| T941 |
439-445 |
NN |
denotes |
factor |
| T944 |
446-450 |
JJ |
denotes |
able |
| T945 |
451-453 |
TO |
denotes |
to |
| T946 |
454-459 |
VB |
denotes |
drive |
| T947 |
460-463 |
DT |
denotes |
the |
| T948 |
464-473 |
NN |
denotes |
formation |
| T949 |
474-476 |
IN |
denotes |
of |
| T950 |
477-487 |
JJ |
denotes |
functional |
| T952 |
488-492 |
NN |
denotes |
type |
| T953 |
493-494 |
CD |
denotes |
I |
| T954 |
495-501 |
NN |
denotes |
muscle |
| T951 |
502-508 |
NNS |
denotes |
fibers |
| T955 |
508-510 |
, |
denotes |
, |
| T956 |
510-515 |
WP$ |
denotes |
whose |
| T957 |
516-526 |
NN |
denotes |
activation |
| T958 |
527-535 |
VBZ |
denotes |
entrains |
| T959 |
536-543 |
JJ |
denotes |
complex |
| T960 |
544-552 |
NNS |
denotes |
pathways |
| T961 |
553-557 |
CC |
denotes |
both |
| T962 |
558-567 |
VBG |
denotes |
enhancing |
| T963 |
568-576 |
JJ |
denotes |
physical |
| T964 |
577-588 |
NN |
denotes |
performance |
| T965 |
589-592 |
CC |
denotes |
and |
| T966 |
593-601 |
VBG |
denotes |
creating |
| T967 |
602-603 |
DT |
denotes |
a |
| T968 |
604-609 |
NN |
denotes |
state |
| T969 |
610-612 |
IN |
denotes |
of |
| T970 |
613-620 |
NN |
denotes |
obesity |
| T971 |
621-631 |
NN |
denotes |
resistance |
| T972 |
631-632 |
. |
denotes |
. |
| R603 |
T864 |
T865 |
nsubj |
We,established |
| R604 |
T866 |
T865 |
aux |
have,established |
| R605 |
T867 |
T865 |
advmod |
previously,established |
| R606 |
T868 |
T869 |
mark |
that,is |
| R607 |
T869 |
T865 |
ccomp |
is,established |
| R608 |
T870 |
T871 |
compound |
peroxisome,proliferator |
| R609 |
T871 |
T872 |
npadvmod |
proliferator,activated |
| R610 |
T872 |
T874 |
amod |
activated,receptor |
| R611 |
T873 |
T872 |
punct |
-,activated |
| R612 |
T874 |
T869 |
nsubj |
receptor,is |
| R613 |
T875 |
T874 |
punct |
(,receptor |
| R614 |
T876 |
T874 |
appos |
PPAR,receptor |
| R615 |
T877 |
T874 |
punct |
),receptor |
| R616 |
T878 |
T874 |
punct |
δ,receptor |
| R617 |
T879 |
T880 |
det |
a,regulator |
| R618 |
T880 |
T869 |
attr |
regulator,is |
| R619 |
T881 |
T880 |
amod |
major,regulator |
| R620 |
T882 |
T880 |
amod |
transcriptional,regulator |
| R621 |
T883 |
T880 |
prep |
of,regulator |
| R622 |
T884 |
T885 |
compound |
fat,burning |
| R623 |
T885 |
T883 |
pobj |
burning,of |
| R624 |
T886 |
T869 |
prep |
in,is |
| R625 |
T887 |
T888 |
compound |
adipose,tissue |
| R626 |
T888 |
T886 |
pobj |
tissue,in |
| R627 |
T889 |
T869 |
prep |
through,is |
| R628 |
T890 |
T889 |
pobj |
activation,through |
| R629 |
T891 |
T890 |
prep |
of,activation |
| R630 |
T892 |
T891 |
pobj |
enzymes,of |
| R631 |
T893 |
T892 |
acl |
associated,enzymes |
| R632 |
T894 |
T893 |
prep |
with,associated |
| R633 |
T895 |
T896 |
amod |
long,chain |
| R634 |
T896 |
T898 |
nmod |
chain,oxidation |
| R635 |
T897 |
T896 |
punct |
-,chain |
| R636 |
T898 |
T894 |
pobj |
oxidation,with |
| R637 |
T899 |
T900 |
amod |
fatty,acid |
| R638 |
T900 |
T898 |
compound |
acid,oxidation |
| R639 |
T901 |
T900 |
punct |
-,acid |
| R640 |
T902 |
T898 |
compound |
β,oxidation |
| R641 |
T903 |
T898 |
punct |
-,oxidation |
| R642 |
T904 |
T905 |
punct |
(,Wang |
| R643 |
T905 |
T865 |
meta |
Wang,established |
| R644 |
T906 |
T905 |
nmod |
et,Wang |
| R645 |
T907 |
T905 |
nmod |
al.,Wang |
| R646 |
T908 |
T905 |
nummod |
2003,Wang |
| R647 |
T909 |
T905 |
punct |
),Wang |
| R648 |
T910 |
T865 |
punct |
.,established |
| R649 |
T912 |
T913 |
mark |
Although,is |
| R650 |
T913 |
T915 |
advcl |
is,determined |
| R651 |
T914 |
T913 |
nsubj |
PPARδ,is |
| R652 |
T916 |
T917 |
det |
the,isoform |
| R653 |
T917 |
T913 |
attr |
isoform,is |
| R654 |
T918 |
T917 |
amod |
predominant,isoform |
| R655 |
T919 |
T917 |
compound |
PPAR,isoform |
| R656 |
T920 |
T917 |
amod |
present,isoform |
| R657 |
T921 |
T920 |
prep |
in,present |
| R658 |
T922 |
T923 |
amod |
skeletal,muscle |
| R659 |
T923 |
T921 |
pobj |
muscle,in |
| R660 |
T924 |
T915 |
punct |
", ",determined |
| R661 |
T925 |
T926 |
poss |
its,function |
| R662 |
T926 |
T915 |
nsubjpass |
function,determined |
| R663 |
T927 |
T928 |
nmod |
in,vivo |
| R664 |
T928 |
T926 |
nmod |
vivo,function |
| R665 |
T929 |
T915 |
aux |
has,determined |
| R666 |
T930 |
T915 |
neg |
not,determined |
| R667 |
T931 |
T915 |
auxpass |
been,determined |
| R668 |
T932 |
T915 |
punct |
.,determined |
| R669 |
T934 |
T935 |
poss |
Our,study |
| R670 |
T935 |
T937 |
nsubj |
study,uncovers |
| R671 |
T936 |
T935 |
amod |
current,study |
| R672 |
T938 |
T937 |
dobj |
PPARδ,uncovers |
| R673 |
T939 |
T937 |
prep |
as,uncovers |
| R674 |
T940 |
T941 |
det |
the,factor |
| R675 |
T941 |
T939 |
pobj |
factor,as |
| R676 |
T942 |
T941 |
amod |
first,factor |
| R677 |
T943 |
T941 |
compound |
transcription,factor |
| R678 |
T944 |
T941 |
amod |
able,factor |
| R679 |
T945 |
T946 |
aux |
to,drive |
| R680 |
T946 |
T944 |
xcomp |
drive,able |
| R681 |
T947 |
T948 |
det |
the,formation |
| R682 |
T948 |
T946 |
dobj |
formation,drive |
| R683 |
T949 |
T948 |
prep |
of,formation |
| R684 |
T950 |
T951 |
amod |
functional,fibers |
| R685 |
T951 |
T949 |
pobj |
fibers,of |
| R686 |
T952 |
T951 |
nmod |
type,fibers |
| R687 |
T953 |
T952 |
nummod |
I,type |
| R688 |
T954 |
T951 |
compound |
muscle,fibers |
| R689 |
T955 |
T941 |
punct |
", ",factor |
| R690 |
T956 |
T957 |
poss |
whose,activation |
| R691 |
T957 |
T958 |
dep |
activation,entrains |
| R692 |
T958 |
T941 |
relcl |
entrains,factor |
| R693 |
T959 |
T960 |
amod |
complex,pathways |
| R694 |
T960 |
T958 |
dobj |
pathways,entrains |
| R695 |
T961 |
T962 |
preconj |
both,enhancing |
| R696 |
T962 |
T960 |
acl |
enhancing,pathways |
| R697 |
T963 |
T964 |
amod |
physical,performance |
| R698 |
T964 |
T962 |
dobj |
performance,enhancing |
| R699 |
T965 |
T962 |
cc |
and,enhancing |
| R700 |
T966 |
T962 |
conj |
creating,enhancing |
| R701 |
T967 |
T968 |
det |
a,state |
| R702 |
T968 |
T966 |
dobj |
state,creating |
| R703 |
T969 |
T968 |
prep |
of,state |
| R704 |
T970 |
T971 |
compound |
obesity,resistance |
| R705 |
T971 |
T969 |
pobj |
resistance,of |
| R706 |
T972 |
T937 |
punct |
.,uncovers |
