Id |
Subject |
Object |
Predicate |
Lexical cue |
T2633 |
0-6 |
NN |
denotes |
Muscle |
T2635 |
7-16 |
JJ |
denotes |
oxidative |
T2634 |
17-25 |
NN |
denotes |
capacity |
T2636 |
26-28 |
VBZ |
denotes |
is |
T2637 |
29-30 |
DT |
denotes |
a |
T2639 |
31-38 |
JJ |
denotes |
crucial |
T2638 |
39-45 |
NN |
denotes |
factor |
T2640 |
46-49 |
IN |
denotes |
for |
T2641 |
50-61 |
VBG |
denotes |
determining |
T2642 |
62-71 |
NN |
denotes |
endurance |
T2643 |
72-75 |
CC |
denotes |
and |
T2644 |
76-83 |
NN |
denotes |
fatigue |
T2645 |
83-84 |
. |
denotes |
. |
T2646 |
84-193 |
sentence |
denotes |
Indeed, type I fibers adaptively generated through exercise training are considered to be fatigue resistant. |
T2647 |
85-91 |
RB |
denotes |
Indeed |
T2649 |
91-93 |
, |
denotes |
, |
T2650 |
93-97 |
NN |
denotes |
type |
T2652 |
98-99 |
CD |
denotes |
I |
T2651 |
100-106 |
NNS |
denotes |
fibers |
T2653 |
107-117 |
RB |
denotes |
adaptively |
T2654 |
118-127 |
VBN |
denotes |
generated |
T2655 |
128-135 |
IN |
denotes |
through |
T2656 |
136-144 |
NN |
denotes |
exercise |
T2657 |
145-153 |
NN |
denotes |
training |
T2658 |
154-157 |
VBP |
denotes |
are |
T2648 |
158-168 |
VBN |
denotes |
considered |
T2659 |
169-171 |
TO |
denotes |
to |
T2660 |
172-174 |
VB |
denotes |
be |
T2661 |
175-182 |
NN |
denotes |
fatigue |
T2662 |
183-192 |
JJ |
denotes |
resistant |
T2663 |
192-193 |
. |
denotes |
. |
T2664 |
193-358 |
sentence |
denotes |
However, whether the type I fibers generated molecularly via PPARδ expression can contribute to enhanced performance in the absence of previous training is unclear. |
T2665 |
194-201 |
RB |
denotes |
However |
T2667 |
201-203 |
, |
denotes |
, |
T2668 |
203-210 |
IN |
denotes |
whether |
T2670 |
211-214 |
DT |
denotes |
the |
T2672 |
215-219 |
NN |
denotes |
type |
T2673 |
220-221 |
CD |
denotes |
I |
T2671 |
222-228 |
NNS |
denotes |
fibers |
T2674 |
229-238 |
VBN |
denotes |
generated |
T2675 |
239-250 |
RB |
denotes |
molecularly |
T2676 |
251-254 |
IN |
denotes |
via |
T2677 |
255-260 |
NN |
denotes |
PPARδ |
T2678 |
261-271 |
NN |
denotes |
expression |
T2679 |
272-275 |
MD |
denotes |
can |
T2669 |
276-286 |
VB |
denotes |
contribute |
T2680 |
287-289 |
IN |
denotes |
to |
T2681 |
290-298 |
VBN |
denotes |
enhanced |
T2682 |
299-310 |
NN |
denotes |
performance |
T2683 |
311-313 |
IN |
denotes |
in |
T2684 |
314-317 |
DT |
denotes |
the |
T2685 |
318-325 |
NN |
denotes |
absence |
T2686 |
326-328 |
IN |
denotes |
of |
T2687 |
329-337 |
JJ |
denotes |
previous |
T2688 |
338-346 |
NN |
denotes |
training |
T2666 |
347-349 |
VBZ |
denotes |
is |
T2689 |
350-357 |
JJ |
denotes |
unclear |
T2690 |
357-358 |
. |
denotes |
. |
T2691 |
358-482 |
sentence |
denotes |
In fact, the consequence of genetically induced fiber switch on running capacity has to our knowledge never been evaluated. |
T2692 |
359-361 |
IN |
denotes |
In |
T2694 |
362-366 |
NN |
denotes |
fact |
T2695 |
366-368 |
, |
denotes |
, |
T2696 |
368-371 |
DT |
denotes |
the |
T2697 |
372-383 |
NN |
denotes |
consequence |
T2698 |
384-386 |
IN |
denotes |
of |
T2699 |
387-398 |
RB |
denotes |
genetically |
T2700 |
399-406 |
VBN |
denotes |
induced |
T2702 |
407-412 |
NN |
denotes |
fiber |
T2701 |
413-419 |
NN |
denotes |
switch |
T2703 |
420-422 |
IN |
denotes |
on |
T2704 |
423-430 |
VBG |
denotes |
running |
T2705 |
431-439 |
NN |
denotes |
capacity |
T2706 |
440-443 |
VBZ |
denotes |
has |
T2707 |
444-446 |
IN |
denotes |
to |
T2708 |
447-450 |
PRP$ |
denotes |
our |
T2709 |
451-460 |
NN |
denotes |
knowledge |
T2710 |
461-466 |
RB |
denotes |
never |
T2711 |
467-471 |
VBN |
denotes |
been |
T2693 |
472-481 |
VBN |
denotes |
evaluated |
T2712 |
481-482 |
. |
denotes |
. |
T2713 |
482-597 |
sentence |
denotes |
We thus compared exercise performance between untrained, body-weight-matched transgenic and wild-type littermates. |
T2714 |
483-485 |
PRP |
denotes |
We |
T2716 |
486-490 |
RB |
denotes |
thus |
T2715 |
491-499 |
VBD |
denotes |
compared |
T2717 |
500-508 |
NN |
denotes |
exercise |
T2718 |
509-520 |
NN |
denotes |
performance |
T2719 |
521-528 |
IN |
denotes |
between |
T2720 |
529-538 |
JJ |
denotes |
untrained |
T2722 |
538-540 |
, |
denotes |
, |
T2723 |
540-544 |
NN |
denotes |
body |
T2725 |
544-545 |
HYPH |
denotes |
- |
T2724 |
545-551 |
NN |
denotes |
weight |
T2727 |
551-552 |
HYPH |
denotes |
- |
T2726 |
552-559 |
VBN |
denotes |
matched |
T2728 |
560-570 |
JJ |
denotes |
transgenic |
T2729 |
571-574 |
CC |
denotes |
and |
T2730 |
575-579 |
JJ |
denotes |
wild |
T2732 |
579-580 |
HYPH |
denotes |
- |
T2731 |
580-584 |
NN |
denotes |
type |
T2721 |
585-596 |
NNS |
denotes |
littermates |
T2733 |
596-597 |
. |
denotes |
. |
T2734 |
597-668 |
sentence |
denotes |
Mice were run on oxygen-infused, enclosed treadmills until exhaustion. |
T2735 |
598-602 |
NNS |
denotes |
Mice |
T2737 |
603-607 |
VBD |
denotes |
were |
T2736 |
608-611 |
VBN |
denotes |
run |
T2738 |
612-614 |
IN |
denotes |
on |
T2739 |
615-621 |
NN |
denotes |
oxygen |
T2741 |
621-622 |
HYPH |
denotes |
- |
T2740 |
622-629 |
VBN |
denotes |
infused |
T2743 |
629-631 |
, |
denotes |
, |
T2744 |
631-639 |
VBN |
denotes |
enclosed |
T2742 |
640-650 |
NNS |
denotes |
treadmills |
T2745 |
651-656 |
IN |
denotes |
until |
T2746 |
657-667 |
NN |
denotes |
exhaustion |
T2747 |
667-668 |
. |
denotes |
. |
T2748 |
668-835 |
sentence |
denotes |
Strikingly, the running time and distance the transgenic mice were able to sustain were increased by 67% and 92%, respectively (Figure 6A; also see Videos S1 and S2). |
T2749 |
669-679 |
RB |
denotes |
Strikingly |
T2751 |
679-681 |
, |
denotes |
, |
T2752 |
681-684 |
DT |
denotes |
the |
T2754 |
685-692 |
NN |
denotes |
running |
T2753 |
693-697 |
NN |
denotes |
time |
T2755 |
698-701 |
CC |
denotes |
and |
T2756 |
702-710 |
NN |
denotes |
distance |
T2757 |
711-714 |
DT |
denotes |
the |
T2759 |
715-725 |
JJ |
denotes |
transgenic |
T2758 |
726-730 |
NNS |
denotes |
mice |
T2760 |
731-735 |
VBD |
denotes |
were |
T2761 |
736-740 |
JJ |
denotes |
able |
T2762 |
741-743 |
TO |
denotes |
to |
T2763 |
744-751 |
VB |
denotes |
sustain |
T2764 |
752-756 |
VBD |
denotes |
were |
T2750 |
757-766 |
VBN |
denotes |
increased |
T2765 |
767-769 |
IN |
denotes |
by |
T2766 |
770-772 |
CD |
denotes |
67 |
T2767 |
772-773 |
NN |
denotes |
% |
T2768 |
774-777 |
CC |
denotes |
and |
T2769 |
778-780 |
CD |
denotes |
92 |
T2770 |
780-781 |
NN |
denotes |
% |
T2771 |
781-783 |
, |
denotes |
, |
T2772 |
783-795 |
RB |
denotes |
respectively |
T2773 |
796-797 |
-LRB- |
denotes |
( |
T2774 |
797-803 |
NN |
denotes |
Figure |
T2775 |
804-806 |
CD |
denotes |
6A |
T2776 |
806-807 |
: |
denotes |
; |
T2777 |
808-812 |
RB |
denotes |
also |
T2778 |
813-816 |
VB |
denotes |
see |
T2779 |
817-823 |
NNS |
denotes |
Videos |
T2780 |
824-826 |
NN |
denotes |
S1 |
T2781 |
827-830 |
CC |
denotes |
and |
T2782 |
831-833 |
NN |
denotes |
S2 |
T2783 |
833-834 |
-RRB- |
denotes |
) |
T2784 |
834-835 |
. |
denotes |
. |
T2785 |
835-943 |
sentence |
denotes |
The transgenic mice ran about 1 h longer than the controls, which translates to nearly a kilometer further. |
T2786 |
836-839 |
DT |
denotes |
The |
T2788 |
840-850 |
JJ |
denotes |
transgenic |
T2787 |
851-855 |
NNS |
denotes |
mice |
T2789 |
856-859 |
VBD |
denotes |
ran |
T2790 |
860-865 |
RB |
denotes |
about |
T2791 |
866-867 |
CD |
denotes |
1 |
T2792 |
868-869 |
NN |
denotes |
h |
T2793 |
870-876 |
RBR |
denotes |
longer |
T2794 |
877-881 |
IN |
denotes |
than |
T2795 |
882-885 |
DT |
denotes |
the |
T2796 |
886-894 |
NNS |
denotes |
controls |
T2797 |
894-896 |
, |
denotes |
, |
T2798 |
896-901 |
WDT |
denotes |
which |
T2799 |
902-912 |
VBZ |
denotes |
translates |
T2800 |
913-915 |
IN |
denotes |
to |
T2801 |
916-922 |
RB |
denotes |
nearly |
T2802 |
923-924 |
DT |
denotes |
a |
T2803 |
925-934 |
NN |
denotes |
kilometer |
T2804 |
935-942 |
RBR |
denotes |
further |
T2805 |
942-943 |
. |
denotes |
. |
T2806 |
943-1190 |
sentence |
denotes |
No significant differences in muscle mass (unpublished data) and daily activity (total counts of activity per hour: 1618 ± 209 for transgenic versus 1987 ± 301 for wild-type, p > 0.35, n = 4) were observed between the transgenic and control mice. |
T2807 |
944-946 |
DT |
denotes |
No |
T2809 |
947-958 |
JJ |
denotes |
significant |
T2808 |
959-970 |
NNS |
denotes |
differences |
T2811 |
971-973 |
IN |
denotes |
in |
T2812 |
974-980 |
NN |
denotes |
muscle |
T2813 |
981-985 |
NN |
denotes |
mass |
T2814 |
986-987 |
-LRB- |
denotes |
( |
T2816 |
987-998 |
JJ |
denotes |
unpublished |
T2815 |
999-1003 |
NNS |
denotes |
data |
T2817 |
1003-1004 |
-RRB- |
denotes |
) |
T2818 |
1005-1008 |
CC |
denotes |
and |
T2819 |
1009-1014 |
JJ |
denotes |
daily |
T2820 |
1015-1023 |
NN |
denotes |
activity |
T2821 |
1024-1025 |
-LRB- |
denotes |
( |
T2823 |
1025-1030 |
JJ |
denotes |
total |
T2824 |
1031-1037 |
NNS |
denotes |
counts |
T2825 |
1038-1040 |
IN |
denotes |
of |
T2826 |
1041-1049 |
NN |
denotes |
activity |
T2827 |
1050-1053 |
IN |
denotes |
per |
T2828 |
1054-1058 |
NN |
denotes |
hour |
T2829 |
1058-1060 |
: |
denotes |
: |
T2830 |
1060-1064 |
CD |
denotes |
1618 |
T2831 |
1065-1066 |
SYM |
denotes |
± |
T2822 |
1067-1070 |
CD |
denotes |
209 |
T2832 |
1071-1074 |
IN |
denotes |
for |
T2833 |
1075-1085 |
JJ |
denotes |
transgenic |
T2834 |
1086-1092 |
CC |
denotes |
versus |
T2835 |
1093-1097 |
CD |
denotes |
1987 |
T2837 |
1098-1099 |
SYM |
denotes |
± |
T2836 |
1100-1103 |
CD |
denotes |
301 |
T2838 |
1104-1107 |
IN |
denotes |
for |
T2839 |
1108-1112 |
JJ |
denotes |
wild |
T2841 |
1112-1113 |
HYPH |
denotes |
- |
T2840 |
1113-1117 |
NN |
denotes |
type |
T2842 |
1117-1119 |
, |
denotes |
, |
T2843 |
1119-1120 |
NN |
denotes |
p |
T2845 |
1121-1122 |
SYM |
denotes |
> |
T2844 |
1123-1127 |
CD |
denotes |
0.35 |
T2846 |
1127-1129 |
, |
denotes |
, |
T2847 |
1129-1130 |
NN |
denotes |
n |
T2849 |
1131-1132 |
SYM |
denotes |
= |
T2848 |
1133-1134 |
CD |
denotes |
4 |
T2850 |
1134-1135 |
-RRB- |
denotes |
) |
T2851 |
1136-1140 |
VBD |
denotes |
were |
T2810 |
1141-1149 |
VBN |
denotes |
observed |
T2852 |
1150-1157 |
IN |
denotes |
between |
T2853 |
1158-1161 |
DT |
denotes |
the |
T2855 |
1162-1172 |
JJ |
denotes |
transgenic |
T2856 |
1173-1176 |
CC |
denotes |
and |
T2857 |
1177-1184 |
NN |
denotes |
control |
T2854 |
1185-1189 |
NNS |
denotes |
mice |
T2858 |
1189-1190 |
. |
denotes |
. |
T2859 |
1190-1298 |
sentence |
denotes |
Thus, the remarkable increase in endurance is the physiologic manifestation of muscle fiber transformation. |
T2860 |
1191-1195 |
RB |
denotes |
Thus |
T2862 |
1195-1197 |
, |
denotes |
, |
T2863 |
1197-1200 |
DT |
denotes |
the |
T2865 |
1201-1211 |
JJ |
denotes |
remarkable |
T2864 |
1212-1220 |
NN |
denotes |
increase |
T2866 |
1221-1223 |
IN |
denotes |
in |
T2867 |
1224-1233 |
NN |
denotes |
endurance |
T2861 |
1234-1236 |
VBZ |
denotes |
is |
T2868 |
1237-1240 |
DT |
denotes |
the |
T2870 |
1241-1252 |
JJ |
denotes |
physiologic |
T2869 |
1253-1266 |
NN |
denotes |
manifestation |
T2871 |
1267-1269 |
IN |
denotes |
of |
T2872 |
1270-1276 |
NN |
denotes |
muscle |
T2873 |
1277-1282 |
NN |
denotes |
fiber |
T2874 |
1283-1297 |
NN |
denotes |
transformation |
T2875 |
1297-1298 |
. |
denotes |
. |
T2876 |
1298-1404 |
sentence |
denotes |
This suggests that genetically directed muscle fiber switch is physiologically and functionally relevant. |
T2877 |
1299-1303 |
DT |
denotes |
This |
T2878 |
1304-1312 |
VBZ |
denotes |
suggests |
T2879 |
1313-1317 |
IN |
denotes |
that |
T2881 |
1318-1329 |
RB |
denotes |
genetically |
T2882 |
1330-1338 |
VBN |
denotes |
directed |
T2884 |
1339-1345 |
NN |
denotes |
muscle |
T2885 |
1346-1351 |
NN |
denotes |
fiber |
T2883 |
1352-1358 |
NN |
denotes |
switch |
T2880 |
1359-1361 |
VBZ |
denotes |
is |
T2886 |
1362-1377 |
RB |
denotes |
physiologically |
T2888 |
1378-1381 |
CC |
denotes |
and |
T2889 |
1382-1394 |
RB |
denotes |
functionally |
T2887 |
1395-1403 |
JJ |
denotes |
relevant |
T2890 |
1403-1404 |
. |
denotes |
. |
T2891 |
1404-1499 |
sentence |
denotes |
In addition, we looked at what effect the absence of PPARδ function has on exercise endurance. |
T2892 |
1405-1407 |
IN |
denotes |
In |
T2894 |
1408-1416 |
NN |
denotes |
addition |
T2895 |
1416-1418 |
, |
denotes |
, |
T2896 |
1418-1420 |
PRP |
denotes |
we |
T2893 |
1421-1427 |
VBD |
denotes |
looked |
T2897 |
1428-1430 |
IN |
denotes |
at |
T2898 |
1431-1435 |
WDT |
denotes |
what |
T2899 |
1436-1442 |
NN |
denotes |
effect |
T2901 |
1443-1446 |
DT |
denotes |
the |
T2902 |
1447-1454 |
NN |
denotes |
absence |
T2903 |
1455-1457 |
IN |
denotes |
of |
T2904 |
1458-1463 |
NN |
denotes |
PPARδ |
T2905 |
1464-1472 |
NN |
denotes |
function |
T2900 |
1473-1476 |
VBZ |
denotes |
has |
T2906 |
1477-1479 |
IN |
denotes |
on |
T2907 |
1480-1488 |
NN |
denotes |
exercise |
T2908 |
1489-1498 |
NN |
denotes |
endurance |
T2909 |
1498-1499 |
. |
denotes |
. |
T2910 |
1499-1678 |
sentence |
denotes |
In the treadmill test, the PPARδ-null mice could sustain only 38% of the running time and 34% of the distance of their age- and weight-matched wild-type counterparts (Figure 6B). |
T2911 |
1500-1502 |
IN |
denotes |
In |
T2913 |
1503-1506 |
DT |
denotes |
the |
T2915 |
1507-1516 |
NN |
denotes |
treadmill |
T2914 |
1517-1521 |
NN |
denotes |
test |
T2916 |
1521-1523 |
, |
denotes |
, |
T2917 |
1523-1526 |
DT |
denotes |
the |
T2919 |
1527-1532 |
NN |
denotes |
PPARδ |
T2921 |
1532-1533 |
HYPH |
denotes |
- |
T2920 |
1533-1537 |
JJ |
denotes |
null |
T2918 |
1538-1542 |
NNS |
denotes |
mice |
T2922 |
1543-1548 |
MD |
denotes |
could |
T2912 |
1549-1556 |
VB |
denotes |
sustain |
T2923 |
1557-1561 |
RB |
denotes |
only |
T2925 |
1562-1564 |
CD |
denotes |
38 |
T2924 |
1564-1565 |
NN |
denotes |
% |
T2926 |
1566-1568 |
IN |
denotes |
of |
T2927 |
1569-1572 |
DT |
denotes |
the |
T2929 |
1573-1580 |
NN |
denotes |
running |
T2928 |
1581-1585 |
NN |
denotes |
time |
T2930 |
1586-1589 |
CC |
denotes |
and |
T2931 |
1590-1592 |
CD |
denotes |
34 |
T2932 |
1592-1593 |
NN |
denotes |
% |
T2933 |
1594-1596 |
IN |
denotes |
of |
T2934 |
1597-1600 |
DT |
denotes |
the |
T2935 |
1601-1609 |
NN |
denotes |
distance |
T2936 |
1610-1612 |
IN |
denotes |
of |
T2937 |
1613-1618 |
PRP$ |
denotes |
their |
T2939 |
1619-1622 |
NN |
denotes |
age |
T2941 |
1622-1623 |
HYPH |
denotes |
- |
T2942 |
1624-1627 |
CC |
denotes |
and |
T2943 |
1628-1634 |
NN |
denotes |
weight |
T2944 |
1634-1635 |
HYPH |
denotes |
- |
T2940 |
1635-1642 |
VBN |
denotes |
matched |
T2945 |
1643-1647 |
JJ |
denotes |
wild |
T2947 |
1647-1648 |
HYPH |
denotes |
- |
T2946 |
1648-1652 |
NN |
denotes |
type |
T2938 |
1653-1665 |
NNS |
denotes |
counterparts |
T2948 |
1666-1667 |
-LRB- |
denotes |
( |
T2949 |
1667-1673 |
NN |
denotes |
Figure |
T2950 |
1674-1676 |
CD |
denotes |
6B |
T2951 |
1676-1677 |
-RRB- |
denotes |
) |
T2952 |
1677-1678 |
. |
denotes |
. |
T2953 |
1678-1765 |
sentence |
denotes |
These results further support a role for PPARδ in enhancement of physical performance. |
T2954 |
1679-1684 |
DT |
denotes |
These |
T2955 |
1685-1692 |
NNS |
denotes |
results |
T2957 |
1693-1700 |
RB |
denotes |
further |
T2956 |
1701-1708 |
VBP |
denotes |
support |
T2958 |
1709-1710 |
DT |
denotes |
a |
T2959 |
1711-1715 |
NN |
denotes |
role |
T2960 |
1716-1719 |
IN |
denotes |
for |
T2961 |
1720-1725 |
NN |
denotes |
PPARδ |
T2962 |
1726-1728 |
IN |
denotes |
in |
T2963 |
1729-1740 |
NN |
denotes |
enhancement |
T2964 |
1741-1743 |
IN |
denotes |
of |
T2965 |
1744-1752 |
JJ |
denotes |
physical |
T2966 |
1753-1764 |
NN |
denotes |
performance |
T2967 |
1764-1765 |
. |
denotes |
. |
R1857 |
T2633 |
T2634 |
nmod |
Muscle,capacity |
R1858 |
T2634 |
T2636 |
nsubj |
capacity,is |
R1859 |
T2635 |
T2634 |
amod |
oxidative,capacity |
R1860 |
T2637 |
T2638 |
det |
a,factor |
R1861 |
T2638 |
T2636 |
attr |
factor,is |
R1862 |
T2639 |
T2638 |
amod |
crucial,factor |
R1863 |
T2640 |
T2638 |
prep |
for,factor |
R1864 |
T2641 |
T2640 |
pcomp |
determining,for |
R1865 |
T2642 |
T2641 |
dobj |
endurance,determining |
R1866 |
T2643 |
T2642 |
cc |
and,endurance |
R1867 |
T2644 |
T2642 |
conj |
fatigue,endurance |
R1868 |
T2645 |
T2636 |
punct |
.,is |
R1869 |
T2647 |
T2648 |
advmod |
Indeed,considered |
R1870 |
T2649 |
T2648 |
punct |
", ",considered |
R1871 |
T2650 |
T2651 |
nmod |
type,fibers |
R1872 |
T2651 |
T2648 |
nsubjpass |
fibers,considered |
R1873 |
T2652 |
T2650 |
nummod |
I,type |
R1874 |
T2653 |
T2654 |
advmod |
adaptively,generated |
R1875 |
T2654 |
T2651 |
acl |
generated,fibers |
R1876 |
T2655 |
T2654 |
prep |
through,generated |
R1877 |
T2656 |
T2657 |
compound |
exercise,training |
R1878 |
T2657 |
T2655 |
pobj |
training,through |
R1879 |
T2658 |
T2648 |
auxpass |
are,considered |
R1880 |
T2659 |
T2660 |
aux |
to,be |
R1881 |
T2660 |
T2648 |
xcomp |
be,considered |
R1882 |
T2661 |
T2662 |
npadvmod |
fatigue,resistant |
R1883 |
T2662 |
T2660 |
acomp |
resistant,be |
R1884 |
T2663 |
T2648 |
punct |
.,considered |
R1885 |
T2665 |
T2666 |
advmod |
However,is |
R1886 |
T2667 |
T2666 |
punct |
", ",is |
R1887 |
T2668 |
T2669 |
mark |
whether,contribute |
R1888 |
T2669 |
T2666 |
csubj |
contribute,is |
R1889 |
T2670 |
T2671 |
det |
the,fibers |
R1890 |
T2671 |
T2669 |
nsubj |
fibers,contribute |
R1891 |
T2672 |
T2671 |
nmod |
type,fibers |
R1892 |
T2673 |
T2672 |
nummod |
I,type |
R1893 |
T2674 |
T2671 |
acl |
generated,fibers |
R1894 |
T2675 |
T2674 |
advmod |
molecularly,generated |
R1895 |
T2676 |
T2674 |
prep |
via,generated |
R1896 |
T2677 |
T2678 |
compound |
PPARδ,expression |
R1897 |
T2678 |
T2676 |
pobj |
expression,via |
R1898 |
T2679 |
T2669 |
aux |
can,contribute |
R1899 |
T2680 |
T2669 |
prep |
to,contribute |
R1900 |
T2681 |
T2682 |
amod |
enhanced,performance |
R1901 |
T2682 |
T2680 |
pobj |
performance,to |
R1902 |
T2683 |
T2669 |
prep |
in,contribute |
R1903 |
T2684 |
T2685 |
det |
the,absence |
R1904 |
T2685 |
T2683 |
pobj |
absence,in |
R1905 |
T2686 |
T2685 |
prep |
of,absence |
R1906 |
T2687 |
T2688 |
amod |
previous,training |
R1907 |
T2688 |
T2686 |
pobj |
training,of |
R1908 |
T2689 |
T2666 |
acomp |
unclear,is |
R1909 |
T2690 |
T2666 |
punct |
.,is |
R1910 |
T2692 |
T2693 |
prep |
In,evaluated |
R1911 |
T2694 |
T2692 |
pobj |
fact,In |
R1912 |
T2695 |
T2693 |
punct |
", ",evaluated |
R1913 |
T2696 |
T2697 |
det |
the,consequence |
R1914 |
T2697 |
T2693 |
nsubjpass |
consequence,evaluated |
R1915 |
T2698 |
T2697 |
prep |
of,consequence |
R1916 |
T2699 |
T2700 |
advmod |
genetically,induced |
R1917 |
T2700 |
T2701 |
amod |
induced,switch |
R1918 |
T2701 |
T2698 |
pobj |
switch,of |
R1919 |
T2702 |
T2701 |
compound |
fiber,switch |
R1920 |
T2703 |
T2697 |
prep |
on,consequence |
R1921 |
T2704 |
T2705 |
amod |
running,capacity |
R1922 |
T2705 |
T2703 |
pobj |
capacity,on |
R1923 |
T2706 |
T2693 |
aux |
has,evaluated |
R1924 |
T2707 |
T2693 |
prep |
to,evaluated |
R1925 |
T2708 |
T2709 |
poss |
our,knowledge |
R1926 |
T2709 |
T2707 |
pobj |
knowledge,to |
R1927 |
T2710 |
T2693 |
neg |
never,evaluated |
R1928 |
T2711 |
T2693 |
auxpass |
been,evaluated |
R1929 |
T2712 |
T2693 |
punct |
.,evaluated |
R1930 |
T2714 |
T2715 |
nsubj |
We,compared |
R1931 |
T2716 |
T2715 |
advmod |
thus,compared |
R1932 |
T2717 |
T2718 |
compound |
exercise,performance |
R1933 |
T2718 |
T2715 |
dobj |
performance,compared |
R1934 |
T2719 |
T2715 |
prep |
between,compared |
R1935 |
T2720 |
T2721 |
amod |
untrained,littermates |
R1936 |
T2721 |
T2719 |
pobj |
littermates,between |
R1937 |
T2722 |
T2721 |
punct |
", ",littermates |
R1938 |
T2723 |
T2724 |
compound |
body,weight |
R1939 |
T2724 |
T2726 |
npadvmod |
weight,matched |
R1940 |
T2725 |
T2724 |
punct |
-,weight |
R1941 |
T2726 |
T2721 |
amod |
matched,littermates |
R1942 |
T2727 |
T2726 |
punct |
-,matched |
R1943 |
T2728 |
T2721 |
amod |
transgenic,littermates |
R1944 |
T2729 |
T2728 |
cc |
and,transgenic |
R1945 |
T2730 |
T2731 |
amod |
wild,type |
R1946 |
T2731 |
T2728 |
conj |
type,transgenic |
R1947 |
T2732 |
T2731 |
punct |
-,type |
R1948 |
T2733 |
T2715 |
punct |
.,compared |
R1949 |
T2735 |
T2736 |
nsubjpass |
Mice,run |
R1950 |
T2737 |
T2736 |
auxpass |
were,run |
R1951 |
T2738 |
T2736 |
prep |
on,run |
R1952 |
T2739 |
T2740 |
npadvmod |
oxygen,infused |
R1953 |
T2740 |
T2742 |
amod |
infused,treadmills |
R1954 |
T2741 |
T2740 |
punct |
-,infused |
R1955 |
T2742 |
T2738 |
pobj |
treadmills,on |
R1956 |
T2743 |
T2742 |
punct |
", ",treadmills |
R1957 |
T2744 |
T2742 |
amod |
enclosed,treadmills |
R1958 |
T2745 |
T2736 |
prep |
until,run |
R1959 |
T2746 |
T2745 |
pobj |
exhaustion,until |
R1960 |
T2747 |
T2736 |
punct |
.,run |
R1961 |
T2749 |
T2750 |
advmod |
Strikingly,increased |
R1962 |
T2751 |
T2750 |
punct |
", ",increased |
R1963 |
T2752 |
T2753 |
det |
the,time |
R1964 |
T2753 |
T2750 |
nsubjpass |
time,increased |
R1965 |
T2754 |
T2753 |
compound |
running,time |
R1966 |
T2755 |
T2753 |
cc |
and,time |
R1967 |
T2756 |
T2753 |
conj |
distance,time |
R1968 |
T2757 |
T2758 |
det |
the,mice |
R1969 |
T2758 |
T2760 |
nsubj |
mice,were |
R1970 |
T2759 |
T2758 |
amod |
transgenic,mice |
R1971 |
T2760 |
T2753 |
advcl |
were,time |
R1972 |
T2761 |
T2760 |
acomp |
able,were |
R1973 |
T2762 |
T2763 |
aux |
to,sustain |
R1974 |
T2763 |
T2761 |
xcomp |
sustain,able |
R1975 |
T2764 |
T2750 |
auxpass |
were,increased |
R1976 |
T2765 |
T2750 |
prep |
by,increased |
R1977 |
T2766 |
T2767 |
nummod |
67,% |
R1978 |
T2767 |
T2765 |
pobj |
%,by |
R1979 |
T2768 |
T2767 |
cc |
and,% |
R1980 |
T2769 |
T2770 |
nummod |
92,% |
R1981 |
T2770 |
T2767 |
conj |
%,% |
R1982 |
T2771 |
T2750 |
punct |
", ",increased |
R1983 |
T2772 |
T2750 |
advmod |
respectively,increased |
R1984 |
T2773 |
T2774 |
punct |
(,Figure |
R1985 |
T2774 |
T2750 |
parataxis |
Figure,increased |
R1986 |
T2775 |
T2774 |
nummod |
6A,Figure |
R1987 |
T2776 |
T2774 |
punct |
;,Figure |
R1988 |
T2777 |
T2778 |
advmod |
also,see |
R1989 |
T2778 |
T2774 |
advcl |
see,Figure |
R1990 |
T2779 |
T2780 |
compound |
Videos,S1 |
R1991 |
T2780 |
T2778 |
dobj |
S1,see |
R1992 |
T2781 |
T2780 |
cc |
and,S1 |
R1993 |
T2782 |
T2780 |
conj |
S2,S1 |
R1994 |
T2783 |
T2774 |
punct |
),Figure |
R1995 |
T2784 |
T2750 |
punct |
.,increased |
R1996 |
T2786 |
T2787 |
det |
The,mice |
R1997 |
T2787 |
T2789 |
nsubj |
mice,ran |
R1998 |
T2788 |
T2787 |
amod |
transgenic,mice |
R1999 |
T2790 |
T2791 |
advmod |
about,1 |
R2000 |
T2791 |
T2792 |
nummod |
1,h |
R2001 |
T2792 |
T2793 |
npadvmod |
h,longer |
R2002 |
T2793 |
T2789 |
advmod |
longer,ran |
R2003 |
T2794 |
T2793 |
prep |
than,longer |
R2004 |
T2795 |
T2796 |
det |
the,controls |
R2005 |
T2796 |
T2794 |
pobj |
controls,than |
R2006 |
T2797 |
T2789 |
punct |
", ",ran |
R2007 |
T2798 |
T2799 |
dep |
which,translates |
R2008 |
T2799 |
T2789 |
advcl |
translates,ran |
R2009 |
T2800 |
T2799 |
prep |
to,translates |
R2010 |
T2801 |
T2802 |
advmod |
nearly,a |
R2011 |
T2802 |
T2803 |
nummod |
a,kilometer |
R2012 |
T2803 |
T2804 |
npadvmod |
kilometer,further |
R2013 |
T2804 |
T2800 |
pcomp |
further,to |
R2014 |
T2805 |
T2789 |
punct |
.,ran |
R2015 |
T2807 |
T2808 |
det |
No,differences |
R2016 |
T2808 |
T2810 |
nsubjpass |
differences,observed |
R2017 |
T2809 |
T2808 |
amod |
significant,differences |
R2018 |
T2811 |
T2808 |
prep |
in,differences |
R2019 |
T2812 |
T2813 |
compound |
muscle,mass |
R2020 |
T2813 |
T2811 |
pobj |
mass,in |
R2021 |
T2814 |
T2815 |
punct |
(,data |
R2022 |
T2815 |
T2813 |
parataxis |
data,mass |
R2023 |
T2816 |
T2815 |
amod |
unpublished,data |
R2024 |
T2817 |
T2815 |
punct |
),data |
R2025 |
T2818 |
T2813 |
cc |
and,mass |
R2026 |
T2819 |
T2820 |
amod |
daily,activity |
R2027 |
T2820 |
T2813 |
conj |
activity,mass |
R2028 |
T2821 |
T2822 |
punct |
(,209 |
R2029 |
T2822 |
T2820 |
parataxis |
209,activity |
R2030 |
T2823 |
T2824 |
amod |
total,counts |
R2031 |
T2824 |
T2822 |
dep |
counts,209 |
R2032 |
T2825 |
T2824 |
prep |
of,counts |
R2033 |
T2826 |
T2825 |
pobj |
activity,of |
R2034 |
T2827 |
T2826 |
prep |
per,activity |
R2035 |
T2828 |
T2827 |
pobj |
hour,per |
R2036 |
T2829 |
T2822 |
punct |
: ,209 |
R2037 |
T2830 |
T2822 |
quantmod |
1618,209 |
R2038 |
T2831 |
T2822 |
punct |
±,209 |
R2039 |
T2832 |
T2822 |
prep |
for,209 |
R2040 |
T2833 |
T2832 |
amod |
transgenic,for |
R2041 |
T2834 |
T2822 |
cc |
versus,209 |
R2042 |
T2835 |
T2836 |
quantmod |
1987,301 |
R2043 |
T2836 |
T2822 |
conj |
301,209 |
R2044 |
T2837 |
T2836 |
punct |
±,301 |
R2045 |
T2838 |
T2836 |
prep |
for,301 |
R2046 |
T2839 |
T2840 |
amod |
wild,type |
R2047 |
T2840 |
T2838 |
pobj |
type,for |
R2048 |
T2841 |
T2840 |
punct |
-,type |
R2049 |
T2842 |
T2822 |
punct |
", ",209 |
R2050 |
T2843 |
T2844 |
nsubj |
p,0.35 |
R2051 |
T2844 |
T2822 |
ccomp |
0.35,209 |
R2052 |
T2845 |
T2844 |
punct |
>,0.35 |
R2053 |
T2846 |
T2822 |
punct |
", ",209 |
R2054 |
T2847 |
T2848 |
nsubj |
n,4 |
R2055 |
T2848 |
T2822 |
ccomp |
4,209 |
R2056 |
T2849 |
T2848 |
punct |
=,4 |
R2057 |
T2850 |
T2822 |
punct |
),209 |
R2058 |
T2851 |
T2810 |
auxpass |
were,observed |
R2059 |
T2852 |
T2810 |
prep |
between,observed |
R2060 |
T2853 |
T2854 |
det |
the,mice |
R2061 |
T2854 |
T2852 |
pobj |
mice,between |
R2062 |
T2855 |
T2854 |
amod |
transgenic,mice |
R2063 |
T2856 |
T2855 |
cc |
and,transgenic |
R2064 |
T2857 |
T2855 |
conj |
control,transgenic |
R2065 |
T2858 |
T2810 |
punct |
.,observed |
R2066 |
T2860 |
T2861 |
advmod |
Thus,is |
R2067 |
T2862 |
T2861 |
punct |
", ",is |
R2068 |
T2863 |
T2864 |
det |
the,increase |
R2069 |
T2864 |
T2861 |
nsubj |
increase,is |
R2070 |
T2865 |
T2864 |
amod |
remarkable,increase |
R2071 |
T2866 |
T2864 |
prep |
in,increase |
R2072 |
T2867 |
T2866 |
pobj |
endurance,in |
R2073 |
T2868 |
T2869 |
det |
the,manifestation |
R2074 |
T2869 |
T2861 |
attr |
manifestation,is |
R2075 |
T2870 |
T2869 |
amod |
physiologic,manifestation |
R2076 |
T2871 |
T2869 |
prep |
of,manifestation |
R2077 |
T2872 |
T2873 |
compound |
muscle,fiber |
R2078 |
T2873 |
T2874 |
compound |
fiber,transformation |
R2079 |
T2874 |
T2871 |
pobj |
transformation,of |
R2080 |
T2875 |
T2861 |
punct |
.,is |
R2081 |
T2877 |
T2878 |
nsubj |
This,suggests |
R2082 |
T2879 |
T2880 |
mark |
that,is |
R2083 |
T2880 |
T2878 |
ccomp |
is,suggests |
R2084 |
T2881 |
T2882 |
advmod |
genetically,directed |
R2085 |
T2882 |
T2883 |
amod |
directed,switch |
R2086 |
T2883 |
T2880 |
nsubj |
switch,is |
R2087 |
T2884 |
T2885 |
compound |
muscle,fiber |
R2088 |
T2885 |
T2883 |
compound |
fiber,switch |
R2089 |
T2886 |
T2887 |
advmod |
physiologically,relevant |
R2090 |
T2887 |
T2880 |
acomp |
relevant,is |
R2091 |
T2888 |
T2886 |
cc |
and,physiologically |
R2092 |
T2889 |
T2886 |
conj |
functionally,physiologically |
R2093 |
T2890 |
T2878 |
punct |
.,suggests |
R2094 |
T2892 |
T2893 |
prep |
In,looked |
R2095 |
T2894 |
T2892 |
pobj |
addition,In |
R2096 |
T2895 |
T2893 |
punct |
", ",looked |
R2097 |
T2896 |
T2893 |
nsubj |
we,looked |
R2098 |
T2897 |
T2893 |
prep |
at,looked |
R2099 |
T2898 |
T2899 |
det |
what,effect |
R2100 |
T2899 |
T2900 |
dep |
effect,has |
R2101 |
T2900 |
T2897 |
pcomp |
has,at |
R2102 |
T2901 |
T2902 |
det |
the,absence |
R2103 |
T2902 |
T2900 |
nsubj |
absence,has |
R2104 |
T2903 |
T2902 |
prep |
of,absence |
R2105 |
T2904 |
T2905 |
compound |
PPARδ,function |
R2106 |
T2905 |
T2903 |
pobj |
function,of |
R2107 |
T2906 |
T2900 |
prep |
on,has |
R2108 |
T2907 |
T2908 |
compound |
exercise,endurance |
R2109 |
T2908 |
T2906 |
pobj |
endurance,on |
R2110 |
T2909 |
T2893 |
punct |
.,looked |
R2111 |
T2911 |
T2912 |
prep |
In,sustain |
R2112 |
T2913 |
T2914 |
det |
the,test |
R2113 |
T2914 |
T2911 |
pobj |
test,In |
R2114 |
T2915 |
T2914 |
compound |
treadmill,test |
R2115 |
T2916 |
T2912 |
punct |
", ",sustain |
R2116 |
T2917 |
T2918 |
det |
the,mice |
R2117 |
T2918 |
T2912 |
nsubj |
mice,sustain |
R2118 |
T2919 |
T2920 |
npadvmod |
PPARδ,null |
R2119 |
T2920 |
T2918 |
amod |
null,mice |
R2120 |
T2921 |
T2920 |
punct |
-,null |
R2121 |
T2922 |
T2912 |
aux |
could,sustain |
R2122 |
T2923 |
T2924 |
advmod |
only,% |
R2123 |
T2924 |
T2912 |
dobj |
%,sustain |
R2124 |
T2925 |
T2924 |
nummod |
38,% |
R2125 |
T2926 |
T2924 |
prep |
of,% |
R2126 |
T2927 |
T2928 |
det |
the,time |
R2127 |
T2928 |
T2926 |
pobj |
time,of |
R2128 |
T2929 |
T2928 |
compound |
running,time |
R2129 |
T2930 |
T2924 |
cc |
and,% |
R2130 |
T2931 |
T2932 |
nummod |
34,% |
R2131 |
T2932 |
T2924 |
conj |
%,% |
R2132 |
T2933 |
T2932 |
prep |
of,% |
R2133 |
T2934 |
T2935 |
det |
the,distance |
R2134 |
T2935 |
T2933 |
pobj |
distance,of |
R2135 |
T2936 |
T2932 |
prep |
of,% |
R2136 |
T2937 |
T2938 |
poss |
their,counterparts |
R2137 |
T2938 |
T2936 |
pobj |
counterparts,of |
R2138 |
T2939 |
T2940 |
npadvmod |
age,matched |
R2139 |
T2940 |
T2938 |
amod |
matched,counterparts |
R2140 |
T2941 |
T2939 |
punct |
-,age |
R2141 |
T2942 |
T2939 |
cc |
and,age |
R2142 |
T2943 |
T2939 |
conj |
weight,age |
R2143 |
T2944 |
T2940 |
punct |
-,matched |
R2144 |
T2945 |
T2946 |
amod |
wild,type |
R2145 |
T2946 |
T2938 |
compound |
type,counterparts |
R2146 |
T2947 |
T2946 |
punct |
-,type |
R2147 |
T2948 |
T2949 |
punct |
(,Figure |
R2148 |
T2949 |
T2912 |
parataxis |
Figure,sustain |
R2149 |
T2950 |
T2949 |
nummod |
6B,Figure |
R2150 |
T2951 |
T2949 |
punct |
),Figure |
R2151 |
T2952 |
T2912 |
punct |
.,sustain |
R2152 |
T2954 |
T2955 |
det |
These,results |
R2153 |
T2955 |
T2956 |
nsubj |
results,support |
R2154 |
T2957 |
T2956 |
advmod |
further,support |
R2155 |
T2958 |
T2959 |
det |
a,role |
R2156 |
T2959 |
T2956 |
dobj |
role,support |
R2157 |
T2960 |
T2959 |
prep |
for,role |
R2158 |
T2961 |
T2960 |
pobj |
PPARδ,for |
R2159 |
T2962 |
T2959 |
prep |
in,role |
R2160 |
T2963 |
T2962 |
pobj |
enhancement,in |
R2161 |
T2964 |
T2963 |
prep |
of,enhancement |
R2162 |
T2965 |
T2966 |
amod |
physical,performance |
R2163 |
T2966 |
T2964 |
pobj |
performance,of |
R2164 |
T2967 |
T2956 |
punct |
.,support |