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PMC:509410 / 10854-14356 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T2215 0-6 NN denotes Muscle
T2216 7-12 NN denotes Fiber
T2217 13-19 NN denotes Switch
T2219 20-22 IN denotes by
T2220 23-28 NN denotes PPARδ
T2218 29-37 VBZ denotes Protects
T2221 38-45 IN denotes Against
T2222 46-53 NN denotes Obesity
T2223 53-237 sentence denotes A number of previous studies have shown that obese individuals have fewer oxidative fibers, implying that the presence of oxidative fibers alone may play a part in obesity resistance.
T2224 54-55 DT denotes A
T2225 56-62 NN denotes number
T2227 63-65 IN denotes of
T2228 66-74 JJ denotes previous
T2229 75-82 NNS denotes studies
T2230 83-87 VBP denotes have
T2226 88-93 VBN denotes shown
T2231 94-98 IN denotes that
T2233 99-104 JJ denotes obese
T2234 105-116 NNS denotes individuals
T2232 117-121 VBP denotes have
T2235 122-127 JJR denotes fewer
T2237 128-137 JJ denotes oxidative
T2236 138-144 NNS denotes fibers
T2238 144-146 , denotes ,
T2239 146-154 VBG denotes implying
T2240 155-159 IN denotes that
T2242 160-163 DT denotes the
T2243 164-172 NN denotes presence
T2244 173-175 IN denotes of
T2245 176-185 JJ denotes oxidative
T2246 186-192 NNS denotes fibers
T2247 193-198 RB denotes alone
T2248 199-202 MD denotes may
T2241 203-207 VB denotes play
T2249 208-209 DT denotes a
T2250 210-214 NN denotes part
T2251 215-217 IN denotes in
T2252 218-225 NN denotes obesity
T2253 226-236 NN denotes resistance
T2254 236-237 . denotes .
T2255 237-353 sentence denotes To test this possibility, we fed the transgenic mice and their wild-type littermates with a high-fat diet for 97 d.
T2256 238-240 TO denotes To
T2257 241-245 VB denotes test
T2259 246-250 DT denotes this
T2260 251-262 NN denotes possibility
T2261 262-264 , denotes ,
T2262 264-266 PRP denotes we
T2258 267-270 VBD denotes fed
T2263 271-274 DT denotes the
T2265 275-285 JJ denotes transgenic
T2264 286-290 NNS denotes mice
T2266 291-294 CC denotes and
T2267 295-300 PRP$ denotes their
T2269 301-305 JJ denotes wild
T2271 305-306 HYPH denotes -
T2270 306-310 NN denotes type
T2268 311-322 NNS denotes littermates
T2272 323-327 IN denotes with
T2273 328-329 DT denotes a
T2275 330-334 JJ denotes high
T2277 334-335 HYPH denotes -
T2276 335-338 NN denotes fat
T2274 339-343 NN denotes diet
T2278 344-347 IN denotes for
T2279 348-350 CD denotes 97
T2280 351-352 NNS denotes d
T2281 352-353 . denotes .
T2282 353-569 sentence denotes Although the initial body weights of the two groups were very similar, the transgenic mice had gained less than 50% at day 47, and only one-third at day 97, of the weight gained by the wild-type animals (Figure 4A).
T2283 354-362 IN denotes Although
T2285 363-366 DT denotes the
T2287 367-374 JJ denotes initial
T2288 375-379 NN denotes body
T2286 380-387 NNS denotes weights
T2289 388-390 IN denotes of
T2290 391-394 DT denotes the
T2292 395-398 CD denotes two
T2291 399-405 NNS denotes groups
T2284 406-410 VBD denotes were
T2294 411-415 RB denotes very
T2295 416-423 JJ denotes similar
T2296 423-425 , denotes ,
T2297 425-428 DT denotes the
T2299 429-439 JJ denotes transgenic
T2298 440-444 NNS denotes mice
T2300 445-448 VBD denotes had
T2293 449-455 VBN denotes gained
T2301 456-460 JJR denotes less
T2303 461-465 IN denotes than
T2302 466-468 CD denotes 50
T2304 468-469 NN denotes %
T2305 470-472 IN denotes at
T2306 473-476 NN denotes day
T2307 477-479 CD denotes 47
T2308 479-481 , denotes ,
T2309 481-484 CC denotes and
T2310 485-489 RB denotes only
T2312 490-493 RB denotes one
T2313 493-494 HYPH denotes -
T2311 494-499 RB denotes third
T2314 500-502 IN denotes at
T2315 503-506 NN denotes day
T2316 507-509 CD denotes 97
T2317 509-511 , denotes ,
T2318 511-513 IN denotes of
T2319 514-517 DT denotes the
T2320 518-524 NN denotes weight
T2321 525-531 VBN denotes gained
T2322 532-534 IN denotes by
T2323 535-538 DT denotes the
T2325 539-543 JJ denotes wild
T2327 543-544 HYPH denotes -
T2326 544-548 NN denotes type
T2324 549-556 NNS denotes animals
T2328 557-558 -LRB- denotes (
T2329 558-564 NN denotes Figure
T2330 565-567 CD denotes 4A
T2331 567-568 -RRB- denotes )
T2332 568-569 . denotes .
T2333 569-709 sentence denotes The transgenic mice displayed significantly higher oxygen consumption on the high-fat diet than the control littermates (unpublished data).
T2334 570-573 DT denotes The
T2336 574-584 JJ denotes transgenic
T2335 585-589 NNS denotes mice
T2337 590-599 VBD denotes displayed
T2338 600-613 RB denotes significantly
T2339 614-620 JJR denotes higher
T2341 621-627 NN denotes oxygen
T2340 628-639 NN denotes consumption
T2342 640-642 IN denotes on
T2343 643-646 DT denotes the
T2345 647-651 JJ denotes high
T2347 651-652 HYPH denotes -
T2346 652-655 NN denotes fat
T2344 656-660 NN denotes diet
T2348 661-665 IN denotes than
T2349 666-669 DT denotes the
T2351 670-677 NN denotes control
T2350 678-689 NNS denotes littermates
T2352 690-691 -LRB- denotes (
T2354 691-702 JJ denotes unpublished
T2353 703-707 NNS denotes data
T2355 707-708 -RRB- denotes )
T2356 708-709 . denotes .
T2357 709-882 sentence denotes By the end of this experiment, the control littermates became obese, whereas the transgenic mice still maintained a normal body weight and fat mass composition (Figure 4A).
T2358 710-712 IN denotes By
T2360 713-716 DT denotes the
T2361 717-720 NN denotes end
T2362 721-723 IN denotes of
T2363 724-728 DT denotes this
T2364 729-739 NN denotes experiment
T2365 739-741 , denotes ,
T2366 741-744 DT denotes the
T2368 745-752 NN denotes control
T2367 753-764 NNS denotes littermates
T2359 765-771 VBD denotes became
T2369 772-777 JJ denotes obese
T2370 777-779 , denotes ,
T2371 779-786 IN denotes whereas
T2373 787-790 DT denotes the
T2375 791-801 JJ denotes transgenic
T2374 802-806 NNS denotes mice
T2376 807-812 RB denotes still
T2372 813-823 VBD denotes maintained
T2377 824-825 DT denotes a
T2379 826-832 JJ denotes normal
T2380 833-837 NN denotes body
T2378 838-844 NN denotes weight
T2381 845-848 CC denotes and
T2382 849-852 NN denotes fat
T2383 853-857 NN denotes mass
T2384 858-869 NN denotes composition
T2385 870-871 -LRB- denotes (
T2386 871-877 NN denotes Figure
T2387 878-880 CD denotes 4A
T2388 880-881 -RRB- denotes )
T2389 881-882 . denotes .
T2390 882-1044 sentence denotes A histological analysis of inguinal fat pad revealed a much smaller cell size in the transgenic mice (Figure 4B), due to the increased muscle oxidative capacity.
T2391 883-884 DT denotes A
T2393 885-897 JJ denotes histological
T2392 898-906 NN denotes analysis
T2395 907-909 IN denotes of
T2396 910-918 JJ denotes inguinal
T2398 919-922 NN denotes fat
T2397 923-926 NN denotes pad
T2394 927-935 VBD denotes revealed
T2399 936-937 DT denotes a
T2401 938-942 RB denotes much
T2402 943-950 JJR denotes smaller
T2403 951-955 NN denotes cell
T2400 956-960 NN denotes size
T2404 961-963 IN denotes in
T2405 964-967 DT denotes the
T2407 968-978 JJ denotes transgenic
T2406 979-983 NNS denotes mice
T2408 984-985 -LRB- denotes (
T2409 985-991 NN denotes Figure
T2410 992-994 CD denotes 4B
T2411 994-995 -RRB- denotes )
T2412 995-997 , denotes ,
T2413 997-1000 IN denotes due
T2414 1001-1003 IN denotes to
T2415 1004-1007 DT denotes the
T2417 1008-1017 VBN denotes increased
T2418 1018-1024 NN denotes muscle
T2419 1025-1034 JJ denotes oxidative
T2416 1035-1043 NN denotes capacity
T2420 1043-1044 . denotes .
T2421 1044-1267 sentence denotes While there was no significant difference in intramuscular glycogen content, the triglyceride content was much less in the transgenic mice (Figure 4C and 4D), which may explain their improved glucose tolerance (Figure 4E).
T2422 1045-1050 IN denotes While
T2424 1051-1056 EX denotes there
T2423 1057-1060 VBD denotes was
T2426 1061-1063 DT denotes no
T2428 1064-1075 JJ denotes significant
T2427 1076-1086 NN denotes difference
T2429 1087-1089 IN denotes in
T2430 1090-1103 JJ denotes intramuscular
T2432 1104-1112 NN denotes glycogen
T2431 1113-1120 NN denotes content
T2433 1120-1122 , denotes ,
T2434 1122-1125 DT denotes the
T2436 1126-1138 NN denotes triglyceride
T2435 1139-1146 NN denotes content
T2425 1147-1150 VBD denotes was
T2437 1151-1155 RB denotes much
T2438 1156-1160 JJR denotes less
T2439 1161-1163 IN denotes in
T2440 1164-1167 DT denotes the
T2442 1168-1178 JJ denotes transgenic
T2441 1179-1183 NNS denotes mice
T2443 1184-1185 -LRB- denotes (
T2444 1185-1191 NN denotes Figure
T2445 1192-1194 CD denotes 4C
T2446 1195-1198 CC denotes and
T2447 1199-1201 CD denotes 4D
T2448 1201-1202 -RRB- denotes )
T2449 1202-1204 , denotes ,
T2450 1204-1209 WDT denotes which
T2452 1210-1213 MD denotes may
T2451 1214-1221 VB denotes explain
T2453 1222-1227 PRP$ denotes their
T2455 1228-1236 VBN denotes improved
T2456 1237-1244 NN denotes glucose
T2454 1245-1254 NN denotes tolerance
T2457 1255-1256 -LRB- denotes (
T2458 1256-1262 NN denotes Figure
T2459 1263-1265 CD denotes 4E
T2460 1265-1266 -RRB- denotes )
T2461 1266-1267 . denotes .
T2462 1267-1402 sentence denotes We also placed wild-type C57BJ6 mice on the high-fat diet and treated them with either vehicle or the PPARδ agonist GW501516 for 2 mo.
T2463 1268-1270 PRP denotes We
T2465 1271-1275 RB denotes also
T2464 1276-1282 VBD denotes placed
T2466 1283-1287 JJ denotes wild
T2468 1287-1288 HYPH denotes -
T2467 1288-1292 NN denotes type
T2470 1293-1299 NN denotes C57BJ6
T2469 1300-1304 NNS denotes mice
T2471 1305-1307 IN denotes on
T2472 1308-1311 DT denotes the
T2474 1312-1316 JJ denotes high
T2476 1316-1317 HYPH denotes -
T2475 1317-1320 NN denotes fat
T2473 1321-1325 NN denotes diet
T2477 1326-1329 CC denotes and
T2478 1330-1337 VBN denotes treated
T2479 1338-1342 PRP denotes them
T2480 1343-1347 IN denotes with
T2481 1348-1354 CC denotes either
T2482 1355-1362 NN denotes vehicle
T2483 1363-1365 CC denotes or
T2484 1366-1369 DT denotes the
T2486 1370-1375 NN denotes PPARδ
T2487 1376-1383 NN denotes agonist
T2485 1384-1392 NN denotes GW501516
T2488 1393-1396 IN denotes for
T2489 1397-1398 CD denotes 2
T2490 1399-1401 NN denotes mo
T2491 1401-1402 . denotes .
T2492 1402-1674 sentence denotes GW501516 produced a sustained induction of genes for type I muscle fibers; this, at least in part, resulted in an only 30% gain in body weight, a dramatically reduced fat mass accumulation, and improved glucose tolerance, compared to the vehicle-treated group (Figure 5).
T2493 1403-1411 NN denotes GW501516
T2494 1412-1420 VBD denotes produced
T2496 1421-1422 DT denotes a
T2498 1423-1432 VBN denotes sustained
T2497 1433-1442 NN denotes induction
T2499 1443-1445 IN denotes of
T2500 1446-1451 NNS denotes genes
T2501 1452-1455 IN denotes for
T2502 1456-1460 NN denotes type
T2504 1461-1462 CD denotes I
T2505 1463-1469 NN denotes muscle
T2503 1470-1476 NNS denotes fibers
T2506 1476-1477 : denotes ;
T2507 1478-1482 DT denotes this
T2508 1482-1484 , denotes ,
T2509 1484-1486 RB denotes at
T2510 1487-1492 RBS denotes least
T2511 1493-1495 IN denotes in
T2512 1496-1500 JJ denotes part
T2513 1500-1502 , denotes ,
T2495 1502-1510 VBD denotes resulted
T2514 1511-1513 IN denotes in
T2515 1514-1516 DT denotes an
T2517 1517-1521 RB denotes only
T2518 1522-1524 CD denotes 30
T2519 1524-1525 NN denotes %
T2516 1526-1530 NN denotes gain
T2520 1531-1533 IN denotes in
T2521 1534-1538 NN denotes body
T2522 1539-1545 NN denotes weight
T2523 1545-1547 , denotes ,
T2524 1547-1548 DT denotes a
T2526 1549-1561 RB denotes dramatically
T2527 1562-1569 VBN denotes reduced
T2528 1570-1573 NN denotes fat
T2529 1574-1578 NN denotes mass
T2525 1579-1591 NN denotes accumulation
T2530 1591-1593 , denotes ,
T2531 1593-1596 CC denotes and
T2532 1597-1605 VBN denotes improved
T2534 1606-1613 NN denotes glucose
T2533 1614-1623 NN denotes tolerance
T2535 1623-1625 , denotes ,
T2536 1625-1633 VBN denotes compared
T2537 1634-1636 IN denotes to
T2538 1637-1640 DT denotes the
T2540 1641-1648 NN denotes vehicle
T2542 1648-1649 HYPH denotes -
T2541 1649-1656 VBN denotes treated
T2539 1657-1662 NN denotes group
T2543 1663-1664 -LRB- denotes (
T2544 1664-1670 NN denotes Figure
T2545 1671-1672 CD denotes 5
T2546 1672-1673 -RRB- denotes )
T2547 1673-1674 . denotes .
T2548 1674-1808 sentence denotes Thus, muscle fiber conversion by stimulation with the PPARδ agonist or the activated transgene has a protective role against obesity.
T2549 1675-1679 RB denotes Thus
T2551 1679-1681 , denotes ,
T2552 1681-1687 NN denotes muscle
T2553 1688-1693 NN denotes fiber
T2554 1694-1704 NN denotes conversion
T2555 1705-1707 IN denotes by
T2556 1708-1719 NN denotes stimulation
T2557 1720-1724 IN denotes with
T2558 1725-1728 DT denotes the
T2560 1729-1734 NN denotes PPARδ
T2559 1735-1742 NN denotes agonist
T2561 1743-1745 CC denotes or
T2562 1746-1749 DT denotes the
T2564 1750-1759 VBN denotes activated
T2563 1760-1769 NN denotes transgene
T2550 1770-1773 VBZ denotes has
T2565 1774-1775 DT denotes a
T2567 1776-1786 JJ denotes protective
T2566 1787-1791 NN denotes role
T2568 1792-1799 IN denotes against
T2569 1800-1807 NN denotes obesity
T2570 1807-1808 . denotes .
T5308 1819-1829 NN denotes Resistance
T5309 1830-1832 IN denotes to
T5310 1833-1837 JJ denotes High
T5312 1837-1838 HYPH denotes -
T5311 1838-1841 NN denotes Fat
T5314 1841-1842 HYPH denotes -
T5313 1842-1849 VBN denotes Induced
T5315 1850-1857 NN denotes Obesity
T5316 1858-1860 IN denotes in
T5317 1861-1864 DT denotes the
T5319 1865-1875 JJ denotes Transgenic
T5318 1876-1880 NNS denotes Mice
T5320 1880-2011 sentence denotes (A) Seven-week-old transgenic (TG) and wild-type (WT) littermates (n = 5–6 for each group) were fed with a high-fat diet for 97 d.
T5321 1881-1882 -LRB- denotes (
T5322 1882-1883 LS denotes A
T5324 1883-1884 -RRB- denotes )
T5325 1885-1890 CD denotes Seven
T5327 1890-1891 HYPH denotes -
T5326 1891-1895 NN denotes week
T5329 1895-1896 HYPH denotes -
T5328 1896-1899 JJ denotes old
T5331 1900-1910 JJ denotes transgenic
T5332 1911-1912 -LRB- denotes (
T5333 1912-1914 JJ denotes TG
T5334 1914-1915 -RRB- denotes )
T5335 1916-1919 CC denotes and
T5336 1920-1924 JJ denotes wild
T5338 1924-1925 HYPH denotes -
T5337 1925-1929 NN denotes type
T5339 1930-1931 -LRB- denotes (
T5340 1931-1933 NN denotes WT
T5341 1933-1934 -RRB- denotes )
T5330 1935-1946 NNS denotes littermates
T5342 1947-1948 -LRB- denotes (
T5344 1948-1949 NN denotes n
T5345 1950-1951 SYM denotes =
T5346 1952-1953 CD denotes 5
T5347 1953-1954 SYM denotes –
T5343 1954-1955 CD denotes 6
T5348 1956-1959 IN denotes for
T5349 1960-1964 DT denotes each
T5350 1965-1970 NN denotes group
T5351 1970-1971 -RRB- denotes )
T5352 1972-1976 VBD denotes were
T5323 1977-1980 VBN denotes fed
T5353 1981-1985 IN denotes with
T5354 1986-1987 DT denotes a
T5356 1988-1992 JJ denotes high
T5358 1992-1993 HYPH denotes -
T5357 1993-1996 NN denotes fat
T5355 1997-2001 NN denotes diet
T5359 2002-2005 IN denotes for
T5360 2006-2008 CD denotes 97
T5361 2009-2010 NN denotes d
T5362 2010-2011 . denotes .
T5363 2011-2110 sentence denotes Left panel shows net body weight gain, which was calculated for individual mice and then averaged.
T5364 2012-2016 JJ denotes Left
T5365 2017-2022 NN denotes panel
T5366 2023-2028 VBZ denotes shows
T5367 2029-2032 JJ denotes net
T5369 2033-2037 NN denotes body
T5370 2038-2044 NN denotes weight
T5368 2045-2049 NN denotes gain
T5371 2049-2051 , denotes ,
T5372 2051-2056 WDT denotes which
T5374 2057-2060 VBD denotes was
T5373 2061-2071 VBN denotes calculated
T5375 2072-2075 IN denotes for
T5376 2076-2086 JJ denotes individual
T5377 2087-2091 NNS denotes mice
T5378 2092-2095 CC denotes and
T5379 2096-2100 RB denotes then
T5380 2101-2109 VBN denotes averaged
T5381 2109-2110 . denotes .
T5382 2110-2197 sentence denotes Right panel shows the body weights before (Day 0) and after (Day 97) high-fat feeding.
T5383 2111-2116 JJ denotes Right
T5384 2117-2122 NN denotes panel
T5385 2123-2128 VBZ denotes shows
T5386 2129-2132 DT denotes the
T5388 2133-2137 NN denotes body
T5387 2138-2145 NNS denotes weights
T5389 2146-2152 IN denotes before
T5390 2153-2154 -LRB- denotes (
T5391 2154-2157 NN denotes Day
T5392 2158-2159 CD denotes 0
T5393 2159-2160 -RRB- denotes )
T5394 2161-2164 CC denotes and
T5395 2165-2170 IN denotes after
T5396 2171-2172 -LRB- denotes (
T5397 2172-2175 NN denotes Day
T5398 2176-2178 CD denotes 97
T5399 2178-2179 -RRB- denotes )
T5400 2180-2184 JJ denotes high
T5402 2184-2185 HYPH denotes -
T5401 2185-2188 NN denotes fat
T5403 2189-2196 NN denotes feeding
T5404 2196-2197 . denotes .
T5405 2197-2307 sentence denotes (B) Histology of inguinal fat pad in the transgenic and wild-type littermates under a high-fat diet for 2 mo.
T5406 2198-2199 -LRB- denotes (
T5407 2199-2200 LS denotes B
T5409 2200-2201 -RRB- denotes )
T5408 2202-2211 NN denotes Histology
T5410 2212-2214 IN denotes of
T5411 2215-2223 JJ denotes inguinal
T5413 2224-2227 NN denotes fat
T5412 2228-2231 NN denotes pad
T5414 2232-2234 IN denotes in
T5415 2235-2238 DT denotes the
T5417 2239-2249 JJ denotes transgenic
T5418 2250-2253 CC denotes and
T5419 2254-2258 JJ denotes wild
T5421 2258-2259 HYPH denotes -
T5420 2259-2263 NN denotes type
T5416 2264-2275 NNS denotes littermates
T5422 2276-2281 IN denotes under
T5423 2282-2283 DT denotes a
T5425 2284-2288 JJ denotes high
T5427 2288-2289 HYPH denotes -
T5426 2289-2292 NN denotes fat
T5424 2293-2297 NN denotes diet
T5428 2298-2301 IN denotes for
T5429 2302-2303 CD denotes 2
T5430 2304-2306 NN denotes mo
T5431 2306-2307 . denotes .
T5432 2307-2428 sentence denotes (C and D) Intramuscular glycogen content (C) and triglyceride content (D) of mice in (A) after high-fat feeding (n = 6).
T5433 2308-2309 -LRB- denotes (
T5434 2309-2310 LS denotes C
T5436 2311-2314 CC denotes and
T5437 2315-2316 LS denotes D
T5438 2316-2317 -RRB- denotes )
T5439 2318-2331 JJ denotes Intramuscular
T5440 2332-2340 NN denotes glycogen
T5435 2341-2348 NN denotes content
T5441 2349-2350 -LRB- denotes (
T5442 2350-2351 NN denotes C
T5443 2351-2352 -RRB- denotes )
T5444 2353-2356 CC denotes and
T5445 2357-2369 NN denotes triglyceride
T5446 2370-2377 NN denotes content
T5447 2378-2379 -LRB- denotes (
T5448 2379-2380 NN denotes D
T5449 2380-2381 -RRB- denotes )
T5450 2382-2384 IN denotes of
T5451 2385-2389 NNS denotes mice
T5452 2390-2392 IN denotes in
T5453 2393-2394 -LRB- denotes (
T5454 2394-2395 NN denotes A
T5455 2395-2396 -RRB- denotes )
T5456 2397-2402 IN denotes after
T5457 2403-2407 JJ denotes high
T5459 2407-2408 HYPH denotes -
T5458 2408-2411 NN denotes fat
T5460 2412-2419 NN denotes feeding
T5461 2420-2421 -LRB- denotes (
T5463 2421-2422 NN denotes n
T5464 2423-2424 SYM denotes =
T5462 2425-2426 CD denotes 6
T5465 2426-2427 -RRB- denotes )
T5466 2427-2428 . denotes .
T5467 2428-2456 sentence denotes (E) Glucose tolerance test.
T5468 2429-2430 -LRB- denotes (
T5469 2430-2431 LS denotes E
T5471 2431-2432 -RRB- denotes )
T5472 2433-2440 NN denotes Glucose
T5473 2441-2450 NN denotes tolerance
T5470 2451-2455 NN denotes test
T5474 2455-2456 . denotes .
T5475 2456-2583 sentence denotes Mice in (A) after high-fat feeding were fasted for 6 h and then injected with glucose at a concentration of 1g/kg body weight.
T5476 2457-2461 NNS denotes Mice
T5478 2462-2464 IN denotes in
T5479 2465-2466 -LRB- denotes (
T5480 2466-2467 NN denotes A
T5481 2467-2468 -RRB- denotes )
T5482 2469-2474 IN denotes after
T5483 2475-2479 JJ denotes high
T5485 2479-2480 HYPH denotes -
T5484 2480-2483 NN denotes fat
T5486 2484-2491 NN denotes feeding
T5487 2492-2496 VBD denotes were
T5477 2497-2503 VBN denotes fasted
T5488 2504-2507 IN denotes for
T5489 2508-2509 CD denotes 6
T5490 2510-2511 NN denotes h
T5491 2512-2515 CC denotes and
T5492 2516-2520 RB denotes then
T5493 2521-2529 VBN denotes injected
T5494 2530-2534 IN denotes with
T5495 2535-2542 NN denotes glucose
T5496 2543-2545 IN denotes at
T5497 2546-2547 DT denotes a
T5498 2548-2561 NN denotes concentration
T5499 2562-2564 IN denotes of
T5500 2565-2567 NN denotes 1g
T5501 2567-2568 SYM denotes /
T5503 2568-2570 NN denotes kg
T5504 2571-2575 NN denotes body
T5502 2576-2582 NN denotes weight
T5505 2582-2583 . denotes .
T5506 2583-2654 sentence denotes Then blood glucose levels were measured periodically over 2 h (n = 6).
T5507 2584-2588 RB denotes Then
T5509 2589-2594 NN denotes blood
T5510 2595-2602 NN denotes glucose
T5511 2603-2609 NNS denotes levels
T5512 2610-2614 VBD denotes were
T5508 2615-2623 VBN denotes measured
T5513 2624-2636 RB denotes periodically
T5514 2637-2641 IN denotes over
T5515 2642-2643 CD denotes 2
T5516 2644-2645 NN denotes h
T5517 2646-2647 -LRB- denotes (
T5519 2647-2648 NN denotes n
T5520 2649-2650 SYM denotes =
T5518 2651-2652 CD denotes 6
T5521 2652-2653 -RRB- denotes )
T5522 2653-2654 . denotes .
T5573 2665-2670 NN denotes PPARδ
T5574 2671-2679 NNS denotes Agonists
T5575 2680-2690 VBP denotes Counteract
T5576 2691-2698 NN denotes Obesity
T5577 2699-2706 VBN denotes Induced
T5578 2707-2709 IN denotes by
T5579 2710-2714 JJ denotes High
T5581 2714-2715 HYPH denotes -
T5580 2715-2718 NN denotes Fat
T5582 2719-2723 NN denotes Diet
T5583 2723-2839 sentence denotes (A) Eleven-week-old wild-type C57B6 mice were fed a high-fat diet in combination with vehicle or GW501516 for 57 d.
T5584 2724-2725 -LRB- denotes (
T5585 2725-2726 LS denotes A
T5587 2726-2727 -RRB- denotes )
T5588 2728-2734 CD denotes Eleven
T5590 2734-2735 HYPH denotes -
T5589 2735-2739 NN denotes week
T5592 2739-2740 HYPH denotes -
T5591 2740-2743 JJ denotes old
T5594 2744-2748 JJ denotes wild
T5596 2748-2749 HYPH denotes -
T5595 2749-2753 NN denotes type
T5597 2754-2759 NN denotes C57B6
T5593 2760-2764 NNS denotes mice
T5598 2765-2769 VBD denotes were
T5586 2770-2773 VBN denotes fed
T5599 2774-2775 DT denotes a
T5601 2776-2780 JJ denotes high
T5603 2780-2781 HYPH denotes -
T5602 2781-2784 NN denotes fat
T5600 2785-2789 NN denotes diet
T5604 2790-2792 IN denotes in
T5605 2793-2804 NN denotes combination
T5606 2805-2809 IN denotes with
T5607 2810-2817 NN denotes vehicle
T5608 2818-2820 CC denotes or
T5609 2821-2829 NN denotes GW501516
T5610 2830-2833 IN denotes for
T5611 2834-2836 CD denotes 57
T5612 2837-2838 NN denotes d
T5613 2838-2839 . denotes .
T5614 2839-2935 sentence denotes Total RNA (10 μg/lane) prepared from the gastrocnemius muscle was probed with indicated probes.
T5615 2840-2845 JJ denotes Total
T5616 2846-2849 NN denotes RNA
T5618 2850-2851 -LRB- denotes (
T5620 2851-2853 CD denotes 10
T5619 2854-2856 NNS denotes μg
T5621 2856-2857 SYM denotes /
T5622 2857-2861 NN denotes lane
T5623 2861-2862 -RRB- denotes )
T5624 2863-2871 VBN denotes prepared
T5625 2872-2876 IN denotes from
T5626 2877-2880 DT denotes the
T5628 2881-2894 NN denotes gastrocnemius
T5627 2895-2901 NN denotes muscle
T5629 2902-2905 VBD denotes was
T5617 2906-2912 VBN denotes probed
T5630 2913-2917 IN denotes with
T5631 2918-2927 VBN denotes indicated
T5632 2928-2934 NNS denotes probes
T5633 2934-2935 . denotes .
T5634 2935-3041 sentence denotes (B) Net body weight gain for mice in (A) after treatment was calculated for individual mice and averaged.
T5635 2936-2937 -LRB- denotes (
T5636 2937-2938 LS denotes B
T5638 2938-2939 -RRB- denotes )
T5639 2940-2943 JJ denotes Net
T5641 2944-2948 NN denotes body
T5642 2949-2955 NN denotes weight
T5640 2956-2960 NN denotes gain
T5643 2961-2964 IN denotes for
T5644 2965-2969 NNS denotes mice
T5645 2970-2972 IN denotes in
T5646 2973-2974 -LRB- denotes (
T5647 2974-2975 NN denotes A
T5648 2975-2976 -RRB- denotes )
T5649 2977-2982 IN denotes after
T5650 2983-2992 NN denotes treatment
T5651 2993-2996 VBD denotes was
T5637 2997-3007 VBN denotes calculated
T5652 3008-3011 IN denotes for
T5653 3012-3022 JJ denotes individual
T5654 3023-3027 NNS denotes mice
T5655 3028-3031 CC denotes and
T5656 3032-3040 VBN denotes averaged
T5657 3040-3041 . denotes .
T5658 3041-3155 sentence denotes Initial body weights were 28.54 ± 1.04 g for vehicle group (n = 5) and 28.86 ± 0.80 g for GW501516 group (n = 5).
T5659 3042-3049 JJ denotes Initial
T5661 3050-3054 NN denotes body
T5660 3055-3062 NNS denotes weights
T5662 3063-3067 VBD denotes were
T5663 3068-3073 CD denotes 28.54
T5665 3074-3075 SYM denotes ±
T5664 3076-3080 CD denotes 1.04
T5666 3081-3082 NNS denotes g
T5667 3083-3086 IN denotes for
T5668 3087-3094 NN denotes vehicle
T5669 3095-3100 NN denotes group
T5670 3101-3102 -LRB- denotes (
T5672 3102-3103 NN denotes n
T5673 3104-3105 SYM denotes =
T5671 3106-3107 CD denotes 5
T5674 3107-3108 -RRB- denotes )
T5675 3109-3112 CC denotes and
T5676 3113-3118 CD denotes 28.86
T5678 3119-3120 SYM denotes ±
T5677 3121-3125 CD denotes 0.80
T5679 3126-3127 NNS denotes g
T5680 3128-3131 IN denotes for
T5681 3132-3140 NN denotes GW501516
T5682 3141-3146 NN denotes group
T5683 3147-3148 -LRB- denotes (
T5685 3148-3149 NN denotes n
T5686 3150-3151 SYM denotes =
T5684 3152-3153 CD denotes 5
T5687 3153-3154 -RRB- denotes )
T5688 3154-3155 . denotes .
T5689 3155-3215 sentence denotes (C) Various tissue weights for mice in (A) after treatment.
T5690 3156-3157 -LRB- denotes (
T5691 3157-3158 LS denotes C
T5693 3158-3159 -RRB- denotes )
T5694 3160-3167 JJ denotes Various
T5695 3168-3174 NN denotes tissue
T5692 3175-3182 NNS denotes weights
T5696 3183-3186 IN denotes for
T5697 3187-3191 NNS denotes mice
T5698 3192-3194 IN denotes in
T5699 3195-3196 -LRB- denotes (
T5700 3196-3197 NN denotes A
T5701 3197-3198 -RRB- denotes )
T5702 3199-3204 IN denotes after
T5703 3205-3214 NN denotes treatment
T5704 3214-3215 . denotes .
T5705 3215-3291 sentence denotes ifat, inguinal fat; rdfat, reproductive fat; retrofat, retroperitoneal fat.
T5706 3216-3220 NN denotes ifat
T5707 3220-3222 , denotes ,
T5708 3222-3230 JJ denotes inguinal
T5709 3231-3234 NN denotes fat
T5710 3234-3235 , denotes ;
T5711 3236-3241 NN denotes rdfat
T5712 3241-3243 , denotes ,
T5713 3243-3255 JJ denotes reproductive
T5714 3256-3259 NN denotes fat
T5715 3259-3260 , denotes ;
T5716 3261-3269 NN denotes retrofat
T5717 3269-3271 , denotes ,
T5718 3271-3286 JJ denotes retroperitoneal
T5719 3287-3290 NN denotes fat
T5720 3290-3291 . denotes .
T5721 3291-3319 sentence denotes (D) Glucose tolerance test.
T5722 3292-3293 -LRB- denotes (
T5723 3293-3294 LS denotes D
T5725 3294-3295 -RRB- denotes )
T5726 3296-3303 NN denotes Glucose
T5727 3304-3313 NN denotes tolerance
T5724 3314-3318 NN denotes test
T5728 3318-3319 . denotes .
T5729 3319-3439 sentence denotes Mice in (A) after treatment were fasted for 6 h and then injected with glucose at a concentration of 1g/kg body weight.
T5730 3320-3324 NNS denotes Mice
T5732 3325-3327 IN denotes in
T5733 3328-3329 -LRB- denotes (
T5734 3329-3330 NN denotes A
T5735 3330-3331 -RRB- denotes )
T5736 3332-3337 IN denotes after
T5737 3338-3347 NN denotes treatment
T5738 3348-3352 VBD denotes were
T5731 3353-3359 VBN denotes fasted
T5739 3360-3363 IN denotes for
T5740 3364-3365 CD denotes 6
T5741 3366-3367 NN denotes h
T5742 3368-3371 CC denotes and
T5743 3372-3376 RB denotes then
T5744 3377-3385 VBN denotes injected
T5745 3386-3390 IN denotes with
T5746 3391-3398 NN denotes glucose
T5747 3399-3401 IN denotes at
T5748 3402-3403 DT denotes a
T5749 3404-3417 NN denotes concentration
T5750 3418-3420 IN denotes of
T5751 3421-3423 NN denotes 1g
T5752 3423-3424 SYM denotes /
T5754 3424-3426 NN denotes kg
T5755 3427-3431 NN denotes body
T5753 3432-3438 NN denotes weight
T5756 3438-3439 . denotes .
T5757 3439-3502 sentence denotes Blood glucose levels were then measured periodically over 2 h.
T5758 3440-3445 NN denotes Blood
T5759 3446-3453 NN denotes glucose
T5760 3454-3460 NNS denotes levels
T5762 3461-3465 VBD denotes were
T5763 3466-3470 RB denotes then
T5761 3471-3479 VBN denotes measured
T5764 3480-3492 RB denotes periodically
T5765 3493-3497 IN denotes over
T5766 3498-3499 CD denotes 2
T5767 3500-3501 NN denotes h
T5768 3501-3502 . denotes .
R1517 T2215 T2216 compound Muscle,Fiber
R1518 T2216 T2217 compound Fiber,Switch
R1519 T2217 T2218 nsubj Switch,Protects
R1520 T2219 T2217 prep by,Switch
R1521 T2220 T2219 pobj PPARδ,by
R1522 T2221 T2218 prep Against,Protects
R1523 T2222 T2221 pobj Obesity,Against
R1524 T2224 T2225 det A,number
R1525 T2225 T2226 nsubj number,shown
R1526 T2227 T2225 prep of,number
R1527 T2228 T2229 amod previous,studies
R1528 T2229 T2227 pobj studies,of
R1529 T2230 T2226 aux have,shown
R1530 T2231 T2232 mark that,have
R1531 T2232 T2226 ccomp have,shown
R1532 T2233 T2234 amod obese,individuals
R1533 T2234 T2232 nsubj individuals,have
R1534 T2235 T2236 amod fewer,fibers
R1535 T2236 T2232 dobj fibers,have
R1536 T2237 T2236 amod oxidative,fibers
R1537 T2238 T2232 punct ", ",have
R1538 T2239 T2232 advcl implying,have
R1539 T2240 T2241 mark that,play
R1540 T2241 T2239 ccomp play,implying
R1541 T2242 T2243 det the,presence
R1542 T2243 T2241 nsubj presence,play
R1543 T2244 T2243 prep of,presence
R1544 T2245 T2246 amod oxidative,fibers
R1545 T2246 T2244 pobj fibers,of
R1546 T2247 T2243 advmod alone,presence
R1547 T2248 T2241 aux may,play
R1548 T2249 T2250 det a,part
R1549 T2250 T2241 dobj part,play
R1550 T2251 T2241 prep in,play
R1551 T2252 T2253 compound obesity,resistance
R1552 T2253 T2251 pobj resistance,in
R1553 T2254 T2226 punct .,shown
R1554 T2256 T2257 aux To,test
R1555 T2257 T2258 advcl test,fed
R1556 T2259 T2260 det this,possibility
R1557 T2260 T2257 dobj possibility,test
R1558 T2261 T2258 punct ", ",fed
R1559 T2262 T2258 nsubj we,fed
R1560 T2263 T2264 det the,mice
R1561 T2264 T2258 dobj mice,fed
R1562 T2265 T2264 amod transgenic,mice
R1563 T2266 T2264 cc and,mice
R1564 T2267 T2268 poss their,littermates
R1565 T2268 T2264 conj littermates,mice
R1566 T2269 T2270 amod wild,type
R1567 T2270 T2268 compound type,littermates
R1568 T2271 T2270 punct -,type
R1569 T2272 T2258 prep with,fed
R1570 T2273 T2274 det a,diet
R1571 T2274 T2272 pobj diet,with
R1572 T2275 T2276 amod high,fat
R1573 T2276 T2274 compound fat,diet
R1574 T2277 T2276 punct -,fat
R1575 T2278 T2258 prep for,fed
R1576 T2279 T2280 nummod 97,d
R1577 T2280 T2278 pobj d,for
R1578 T2281 T2258 punct .,fed
R1579 T2283 T2284 mark Although,were
R1580 T2284 T2293 advcl were,gained
R1581 T2285 T2286 det the,weights
R1582 T2286 T2284 nsubj weights,were
R1583 T2287 T2286 amod initial,weights
R1584 T2288 T2286 compound body,weights
R1585 T2289 T2286 prep of,weights
R1586 T2290 T2291 det the,groups
R1587 T2291 T2289 pobj groups,of
R1588 T2292 T2291 nummod two,groups
R1589 T2294 T2295 advmod very,similar
R1590 T2295 T2284 acomp similar,were
R1591 T2296 T2293 punct ", ",gained
R1592 T2297 T2298 det the,mice
R1593 T2298 T2293 nsubj mice,gained
R1594 T2299 T2298 amod transgenic,mice
R1595 T2300 T2293 aux had,gained
R1596 T2301 T2302 amod less,50
R1597 T2302 T2304 nummod 50,%
R1598 T2303 T2302 quantmod than,50
R1599 T2304 T2293 dobj %,gained
R1600 T2305 T2293 prep at,gained
R1601 T2306 T2305 pobj day,at
R1602 T2307 T2306 nummod 47,day
R1603 T2308 T2293 punct ", ",gained
R1604 T2309 T2293 cc and,gained
R1605 T2310 T2311 advmod only,third
R1606 T2311 T2293 conj third,gained
R1607 T2312 T2311 advmod one,third
R1608 T2313 T2311 punct -,third
R1609 T2314 T2311 prep at,third
R1610 T2315 T2314 pobj day,at
R1611 T2316 T2315 nummod 97,day
R1612 T2317 T2311 punct ", ",third
R1613 T2318 T2311 conj of,third
R1614 T2319 T2320 det the,weight
R1615 T2320 T2318 pobj weight,of
R1616 T2321 T2320 acl gained,weight
R1617 T2322 T2321 agent by,gained
R1618 T2323 T2324 det the,animals
R1619 T2324 T2322 pobj animals,by
R1620 T2325 T2326 amod wild,type
R1621 T2326 T2324 compound type,animals
R1622 T2327 T2326 punct -,type
R1623 T2328 T2329 punct (,Figure
R1624 T2329 T2318 parataxis Figure,of
R1625 T2330 T2329 nummod 4A,Figure
R1626 T2331 T2329 punct ),Figure
R1627 T2332 T2293 punct .,gained
R1628 T2334 T2335 det The,mice
R1629 T2335 T2337 nsubj mice,displayed
R1630 T2336 T2335 amod transgenic,mice
R1631 T2338 T2339 advmod significantly,higher
R1632 T2339 T2340 amod higher,consumption
R1633 T2340 T2337 dobj consumption,displayed
R1634 T2341 T2340 compound oxygen,consumption
R1635 T2342 T2340 prep on,consumption
R1636 T2343 T2344 det the,diet
R1637 T2344 T2342 pobj diet,on
R1638 T2345 T2346 amod high,fat
R1639 T2346 T2344 compound fat,diet
R1640 T2347 T2346 punct -,fat
R1641 T2348 T2340 prep than,consumption
R1642 T2349 T2350 det the,littermates
R1643 T2350 T2348 pobj littermates,than
R1644 T2351 T2350 compound control,littermates
R1645 T2352 T2353 punct (,data
R1646 T2353 T2337 parataxis data,displayed
R1647 T2354 T2353 amod unpublished,data
R1648 T2355 T2353 punct ),data
R1649 T2356 T2337 punct .,displayed
R1650 T2358 T2359 prep By,became
R1651 T2360 T2361 det the,end
R1652 T2361 T2358 pobj end,By
R1653 T2362 T2361 prep of,end
R1654 T2363 T2364 det this,experiment
R1655 T2364 T2362 pobj experiment,of
R1656 T2365 T2359 punct ", ",became
R1657 T2366 T2367 det the,littermates
R1658 T2367 T2359 nsubj littermates,became
R1659 T2368 T2367 compound control,littermates
R1660 T2369 T2359 attr obese,became
R1661 T2370 T2359 punct ", ",became
R1662 T2371 T2372 mark whereas,maintained
R1663 T2372 T2359 advcl maintained,became
R1664 T2373 T2374 det the,mice
R1665 T2374 T2372 nsubj mice,maintained
R1666 T2375 T2374 amod transgenic,mice
R1667 T2376 T2372 advmod still,maintained
R1668 T2377 T2378 det a,weight
R1669 T2378 T2372 dobj weight,maintained
R1670 T2379 T2378 amod normal,weight
R1671 T2380 T2378 compound body,weight
R1672 T2381 T2378 cc and,weight
R1673 T2382 T2383 compound fat,mass
R1674 T2383 T2384 compound mass,composition
R1675 T2384 T2378 conj composition,weight
R1676 T2385 T2386 punct (,Figure
R1677 T2386 T2372 parataxis Figure,maintained
R1678 T2387 T2386 nummod 4A,Figure
R1679 T2388 T2386 punct ),Figure
R1680 T2389 T2359 punct .,became
R1681 T2391 T2392 det A,analysis
R1682 T2392 T2394 nsubj analysis,revealed
R1683 T2393 T2392 amod histological,analysis
R1684 T2395 T2392 prep of,analysis
R1685 T2396 T2397 amod inguinal,pad
R1686 T2397 T2395 pobj pad,of
R1687 T2398 T2397 compound fat,pad
R1688 T2399 T2400 det a,size
R1689 T2400 T2394 dobj size,revealed
R1690 T2401 T2402 advmod much,smaller
R1691 T2402 T2400 amod smaller,size
R1692 T2403 T2400 compound cell,size
R1693 T2404 T2394 prep in,revealed
R1694 T2405 T2406 det the,mice
R1695 T2406 T2404 pobj mice,in
R1696 T2407 T2406 amod transgenic,mice
R1697 T2408 T2409 punct (,Figure
R1698 T2409 T2394 parataxis Figure,revealed
R1699 T2410 T2409 nummod 4B,Figure
R1700 T2411 T2409 punct ),Figure
R1701 T2412 T2394 punct ", ",revealed
R1702 T2413 T2394 prep due,revealed
R1703 T2414 T2413 pcomp to,due
R1704 T2415 T2416 det the,capacity
R1705 T2416 T2413 pobj capacity,due
R1706 T2417 T2416 amod increased,capacity
R1707 T2418 T2416 nmod muscle,capacity
R1708 T2419 T2416 amod oxidative,capacity
R1709 T2420 T2394 punct .,revealed
R1710 T2422 T2423 mark While,was
R1711 T2423 T2425 advcl was,was
R1712 T2424 T2423 expl there,was
R1713 T2426 T2427 det no,difference
R1714 T2427 T2423 attr difference,was
R1715 T2428 T2427 amod significant,difference
R1716 T2429 T2427 prep in,difference
R1717 T2430 T2431 amod intramuscular,content
R1718 T2431 T2429 pobj content,in
R1719 T2432 T2431 compound glycogen,content
R1720 T2433 T2425 punct ", ",was
R1721 T2434 T2435 det the,content
R1722 T2435 T2425 nsubj content,was
R1723 T2436 T2435 compound triglyceride,content
R1724 T2437 T2438 advmod much,less
R1725 T2438 T2425 acomp less,was
R1726 T2439 T2425 prep in,was
R1727 T2440 T2441 det the,mice
R1728 T2441 T2439 pobj mice,in
R1729 T2442 T2441 amod transgenic,mice
R1730 T2443 T2444 punct (,Figure
R1731 T2444 T2425 parataxis Figure,was
R1732 T2445 T2444 nummod 4C,Figure
R1733 T2446 T2444 cc and,Figure
R1734 T2447 T2444 conj 4D,Figure
R1735 T2448 T2444 punct ),Figure
R1736 T2449 T2425 punct ", ",was
R1737 T2450 T2451 dep which,explain
R1738 T2451 T2425 advcl explain,was
R1739 T2452 T2451 aux may,explain
R1740 T2453 T2454 poss their,tolerance
R1741 T2454 T2451 dobj tolerance,explain
R1742 T2455 T2454 amod improved,tolerance
R1743 T2456 T2454 compound glucose,tolerance
R1744 T2457 T2458 punct (,Figure
R1745 T2458 T2451 parataxis Figure,explain
R1746 T2459 T2458 nummod 4E,Figure
R1747 T2460 T2458 punct ),Figure
R1748 T2461 T2425 punct .,was
R1749 T2463 T2464 nsubj We,placed
R1750 T2465 T2464 advmod also,placed
R1751 T2466 T2467 amod wild,type
R1752 T2467 T2469 compound type,mice
R1753 T2468 T2467 punct -,type
R1754 T2469 T2464 dobj mice,placed
R1755 T2470 T2469 compound C57BJ6,mice
R1756 T2471 T2464 prep on,placed
R1757 T2472 T2473 det the,diet
R1758 T2473 T2471 pobj diet,on
R1759 T2474 T2475 amod high,fat
R1760 T2475 T2473 compound fat,diet
R1761 T2476 T2475 punct -,fat
R1762 T2477 T2464 cc and,placed
R1763 T2478 T2464 conj treated,placed
R1764 T2479 T2478 dobj them,treated
R1765 T2480 T2478 prep with,treated
R1766 T2481 T2482 preconj either,vehicle
R1767 T2482 T2480 pobj vehicle,with
R1768 T2483 T2482 cc or,vehicle
R1769 T2484 T2485 det the,GW501516
R1770 T2485 T2482 conj GW501516,vehicle
R1771 T2486 T2487 compound PPARδ,agonist
R1772 T2487 T2485 compound agonist,GW501516
R1773 T2488 T2478 prep for,treated
R1774 T2489 T2490 nummod 2,mo
R1775 T2490 T2488 pobj mo,for
R1776 T2491 T2464 punct .,placed
R1777 T2493 T2494 nsubj GW501516,produced
R1778 T2494 T2495 ccomp produced,resulted
R1779 T2496 T2497 det a,induction
R1780 T2497 T2494 dobj induction,produced
R1781 T2498 T2497 amod sustained,induction
R1782 T2499 T2497 prep of,induction
R1783 T2500 T2499 pobj genes,of
R1784 T2501 T2500 prep for,genes
R1785 T2502 T2503 nmod type,fibers
R1786 T2503 T2501 pobj fibers,for
R1787 T2504 T2502 nummod I,type
R1788 T2505 T2503 compound muscle,fibers
R1789 T2506 T2495 punct ;,resulted
R1790 T2507 T2495 nsubj this,resulted
R1791 T2508 T2495 punct ", ",resulted
R1792 T2509 T2510 advmod at,least
R1793 T2510 T2511 advmod least,in
R1794 T2511 T2495 prep in,resulted
R1795 T2512 T2511 amod part,in
R1796 T2513 T2495 punct ", ",resulted
R1797 T2514 T2495 prep in,resulted
R1798 T2515 T2516 det an,gain
R1799 T2516 T2514 pobj gain,in
R1800 T2517 T2518 advmod only,30
R1801 T2518 T2519 nummod 30,%
R1802 T2519 T2516 compound %,gain
R1803 T2520 T2516 prep in,gain
R1804 T2521 T2522 compound body,weight
R1805 T2522 T2520 pobj weight,in
R1806 T2523 T2516 punct ", ",gain
R1807 T2524 T2525 det a,accumulation
R1808 T2525 T2516 conj accumulation,gain
R1809 T2526 T2527 advmod dramatically,reduced
R1810 T2527 T2525 amod reduced,accumulation
R1811 T2528 T2529 compound fat,mass
R1812 T2529 T2525 compound mass,accumulation
R1813 T2530 T2525 punct ", ",accumulation
R1814 T2531 T2525 cc and,accumulation
R1815 T2532 T2533 amod improved,tolerance
R1816 T2533 T2525 conj tolerance,accumulation
R1817 T2534 T2533 compound glucose,tolerance
R1818 T2535 T2516 punct ", ",gain
R1819 T2536 T2516 prep compared,gain
R1820 T2537 T2536 prep to,compared
R1821 T2538 T2539 det the,group
R1822 T2539 T2537 pobj group,to
R1823 T2540 T2541 npadvmod vehicle,treated
R1824 T2541 T2539 amod treated,group
R1825 T2542 T2541 punct -,treated
R1826 T2543 T2544 punct (,Figure
R1827 T2544 T2495 parataxis Figure,resulted
R1828 T2545 T2544 nummod 5,Figure
R1829 T2546 T2544 punct ),Figure
R1830 T2547 T2495 punct .,resulted
R1831 T2549 T2550 advmod Thus,has
R1832 T2551 T2550 punct ", ",has
R1833 T2552 T2553 compound muscle,fiber
R1834 T2553 T2554 compound fiber,conversion
R1835 T2554 T2550 nsubj conversion,has
R1836 T2555 T2554 prep by,conversion
R1837 T2556 T2555 pobj stimulation,by
R1838 T2557 T2556 prep with,stimulation
R1839 T2558 T2559 det the,agonist
R1840 T2559 T2557 pobj agonist,with
R1841 T2560 T2559 compound PPARδ,agonist
R1842 T2561 T2559 cc or,agonist
R1843 T2562 T2563 det the,transgene
R1844 T2563 T2559 conj transgene,agonist
R1845 T2564 T2563 amod activated,transgene
R1846 T2565 T2566 det a,role
R1847 T2566 T2550 dobj role,has
R1848 T2567 T2566 amod protective,role
R1849 T2568 T2566 prep against,role
R1850 T2569 T2568 pobj obesity,against
R1851 T2570 T2550 punct .,has
R3791 T5309 T5308 prep to,Resistance
R3792 T5310 T5311 amod High,Fat
R3793 T5311 T5313 npadvmod Fat,Induced
R3794 T5312 T5311 punct -,Fat
R3795 T5313 T5315 amod Induced,Obesity
R3796 T5314 T5313 punct -,Induced
R3797 T5315 T5309 pobj Obesity,to
R3798 T5316 T5308 prep in,Resistance
R3799 T5317 T5318 det the,Mice
R3800 T5318 T5316 pobj Mice,in
R3801 T5319 T5318 amod Transgenic,Mice
R3802 T5321 T5322 punct (,A
R3803 T5322 T5323 meta A,fed
R3804 T5324 T5322 punct ),A
R3805 T5325 T5326 nummod Seven,week
R3806 T5326 T5328 npadvmod week,old
R3807 T5327 T5326 punct -,week
R3808 T5328 T5330 amod old,littermates
R3809 T5329 T5328 punct -,old
R3810 T5330 T5323 nsubjpass littermates,fed
R3811 T5331 T5330 amod transgenic,littermates
R3812 T5332 T5333 punct (,TG
R3813 T5333 T5331 parataxis TG,transgenic
R3814 T5334 T5333 punct ),TG
R3815 T5335 T5331 cc and,transgenic
R3816 T5336 T5337 amod wild,type
R3817 T5337 T5331 conj type,transgenic
R3818 T5338 T5337 punct -,type
R3819 T5339 T5340 punct (,WT
R3820 T5340 T5337 parataxis WT,type
R3821 T5341 T5340 punct ),WT
R3822 T5342 T5343 punct (,6
R3823 T5343 T5330 parataxis 6,littermates
R3824 T5344 T5343 nsubj n,6
R3825 T5345 T5343 punct =,6
R3826 T5346 T5343 quantmod 5,6
R3827 T5347 T5343 punct –,6
R3828 T5348 T5343 prep for,6
R3829 T5349 T5350 det each,group
R3830 T5350 T5348 pobj group,for
R3831 T5351 T5343 punct ),6
R3832 T5352 T5323 auxpass were,fed
R3833 T5353 T5323 prep with,fed
R3834 T5354 T5355 det a,diet
R3835 T5355 T5353 pobj diet,with
R3836 T5356 T5357 amod high,fat
R3837 T5357 T5355 compound fat,diet
R3838 T5358 T5357 punct -,fat
R3839 T5359 T5323 prep for,fed
R3840 T5360 T5361 nummod 97,d
R3841 T5361 T5359 pobj d,for
R3842 T5362 T5323 punct .,fed
R3843 T5364 T5365 amod Left,panel
R3844 T5365 T5366 nsubj panel,shows
R3845 T5367 T5368 amod net,gain
R3846 T5368 T5366 dobj gain,shows
R3847 T5369 T5370 compound body,weight
R3848 T5370 T5368 compound weight,gain
R3849 T5371 T5368 punct ", ",gain
R3850 T5372 T5373 dep which,calculated
R3851 T5373 T5368 relcl calculated,gain
R3852 T5374 T5373 auxpass was,calculated
R3853 T5375 T5373 prep for,calculated
R3854 T5376 T5377 amod individual,mice
R3855 T5377 T5375 pobj mice,for
R3856 T5378 T5373 cc and,calculated
R3857 T5379 T5380 advmod then,averaged
R3858 T5380 T5373 conj averaged,calculated
R3859 T5381 T5366 punct .,shows
R3860 T5383 T5384 amod Right,panel
R3861 T5384 T5385 nsubj panel,shows
R3862 T5386 T5387 det the,weights
R3863 T5387 T5385 dobj weights,shows
R3864 T5388 T5387 compound body,weights
R3865 T5389 T5385 prep before,shows
R3866 T5390 T5391 punct (,Day
R3867 T5391 T5389 parataxis Day,before
R3868 T5392 T5391 nummod 0,Day
R3869 T5393 T5391 punct ),Day
R3870 T5394 T5389 cc and,before
R3871 T5395 T5389 conj after,before
R3872 T5396 T5397 punct (,Day
R3873 T5397 T5395 parataxis Day,after
R3874 T5398 T5397 nummod 97,Day
R3875 T5399 T5397 punct ),Day
R3876 T5400 T5401 amod high,fat
R3877 T5401 T5403 compound fat,feeding
R3878 T5402 T5401 punct -,fat
R3879 T5403 T5395 pobj feeding,after
R3880 T5404 T5385 punct .,shows
R3881 T5406 T5407 punct (,B
R3882 T5407 T5408 meta B,Histology
R3883 T5409 T5407 punct ),B
R3884 T5410 T5408 prep of,Histology
R3885 T5411 T5412 amod inguinal,pad
R3886 T5412 T5410 pobj pad,of
R3887 T5413 T5412 compound fat,pad
R3888 T5414 T5408 prep in,Histology
R3889 T5415 T5416 det the,littermates
R3890 T5416 T5414 pobj littermates,in
R3891 T5417 T5416 amod transgenic,littermates
R3892 T5418 T5417 cc and,transgenic
R3893 T5419 T5420 amod wild,type
R3894 T5420 T5417 conj type,transgenic
R3895 T5421 T5420 punct -,type
R3896 T5422 T5408 prep under,Histology
R3897 T5423 T5424 det a,diet
R3898 T5424 T5422 pobj diet,under
R3899 T5425 T5426 amod high,fat
R3900 T5426 T5424 compound fat,diet
R3901 T5427 T5426 punct -,fat
R3902 T5428 T5408 prep for,Histology
R3903 T5429 T5430 nummod 2,mo
R3904 T5430 T5428 pobj mo,for
R3905 T5431 T5408 punct .,Histology
R3906 T5433 T5434 punct (,C
R3907 T5434 T5435 meta C,content
R3908 T5436 T5434 cc and,C
R3909 T5437 T5434 conj D,C
R3910 T5438 T5437 punct ),D
R3911 T5439 T5435 amod Intramuscular,content
R3912 T5440 T5435 compound glycogen,content
R3913 T5441 T5442 punct (,C
R3914 T5442 T5435 parataxis C,content
R3915 T5443 T5442 punct ),C
R3916 T5444 T5435 cc and,content
R3917 T5445 T5446 compound triglyceride,content
R3918 T5446 T5435 conj content,content
R3919 T5447 T5448 punct (,D
R3920 T5448 T5446 parataxis D,content
R3921 T5449 T5448 punct ),D
R3922 T5450 T5435 prep of,content
R3923 T5451 T5450 pobj mice,of
R3924 T5452 T5451 prep in,mice
R3925 T5453 T5452 punct (,in
R3926 T5454 T5452 pobj A,in
R3927 T5455 T5452 punct ),in
R3928 T5456 T5435 prep after,content
R3929 T5457 T5458 amod high,fat
R3930 T5458 T5460 compound fat,feeding
R3931 T5459 T5458 punct -,fat
R3932 T5460 T5456 pobj feeding,after
R3933 T5461 T5462 punct (,6
R3934 T5462 T5435 parataxis 6,content
R3935 T5463 T5462 nsubj n,6
R3936 T5464 T5462 punct =,6
R3937 T5465 T5462 punct ),6
R3938 T5466 T5435 punct .,content
R3939 T5468 T5469 punct (,E
R3940 T5469 T5470 meta E,test
R3941 T5471 T5469 punct ),E
R3942 T5472 T5473 compound Glucose,tolerance
R3943 T5473 T5470 compound tolerance,test
R3944 T5474 T5470 punct .,test
R3945 T5476 T5477 nsubjpass Mice,fasted
R3946 T5478 T5476 prep in,Mice
R3947 T5479 T5478 punct (,in
R3948 T5480 T5478 pobj A,in
R3949 T5481 T5478 punct ),in
R3950 T5482 T5476 prep after,Mice
R3951 T5483 T5484 amod high,fat
R3952 T5484 T5486 compound fat,feeding
R3953 T5485 T5484 punct -,fat
R3954 T5486 T5482 pobj feeding,after
R3955 T5487 T5477 auxpass were,fasted
R3956 T5488 T5477 prep for,fasted
R3957 T5489 T5490 nummod 6,h
R3958 T5490 T5488 pobj h,for
R3959 T5491 T5477 cc and,fasted
R3960 T5492 T5493 advmod then,injected
R3961 T5493 T5477 conj injected,fasted
R3962 T5494 T5493 prep with,injected
R3963 T5495 T5494 pobj glucose,with
R3964 T5496 T5493 prep at,injected
R3965 T5497 T5498 det a,concentration
R3966 T5498 T5496 pobj concentration,at
R3967 T5499 T5498 prep of,concentration
R3968 T5500 T5499 pobj 1g,of
R3969 T5501 T5502 punct /,weight
R3970 T5502 T5500 prep weight,1g
R3971 T5503 T5502 compound kg,weight
R3972 T5504 T5502 compound body,weight
R3973 T5505 T5477 punct .,fasted
R3974 T5507 T5508 advmod Then,measured
R3975 T5509 T5510 compound blood,glucose
R3976 T5510 T5511 compound glucose,levels
R3977 T5511 T5508 nsubjpass levels,measured
R3978 T5512 T5508 auxpass were,measured
R3979 T5513 T5508 advmod periodically,measured
R3980 T5514 T5508 prep over,measured
R3981 T5515 T5516 nummod 2,h
R3982 T5516 T5514 pobj h,over
R3983 T5517 T5518 punct (,6
R3984 T5518 T5508 parataxis 6,measured
R3985 T5519 T5518 nsubj n,6
R3986 T5520 T5518 punct =,6
R3987 T5521 T5518 punct ),6
R3988 T5522 T5508 punct .,measured
R3989 T5573 T5574 compound PPARδ,Agonists
R3990 T5574 T5575 nsubj Agonists,Counteract
R3991 T5576 T5575 dobj Obesity,Counteract
R3992 T5577 T5576 acl Induced,Obesity
R3993 T5578 T5577 agent by,Induced
R3994 T5579 T5580 amod High,Fat
R3995 T5580 T5582 compound Fat,Diet
R3996 T5581 T5580 punct -,Fat
R3997 T5582 T5578 pobj Diet,by
R3998 T5584 T5585 punct (,A
R3999 T5585 T5586 meta A,fed
R4000 T5587 T5585 punct ),A
R4001 T5588 T5589 nummod Eleven,week
R4002 T5589 T5591 npadvmod week,old
R4003 T5590 T5589 punct -,week
R4004 T5591 T5593 amod old,mice
R4005 T5592 T5591 punct -,old
R4006 T5593 T5586 nsubjpass mice,fed
R4007 T5594 T5595 amod wild,type
R4008 T5595 T5593 compound type,mice
R4009 T5596 T5595 punct -,type
R4010 T5597 T5593 compound C57B6,mice
R4011 T5598 T5586 auxpass were,fed
R4012 T5599 T5600 det a,diet
R4013 T5600 T5586 dobj diet,fed
R4014 T5601 T5602 amod high,fat
R4015 T5602 T5600 compound fat,diet
R4016 T5603 T5602 punct -,fat
R4017 T5604 T5586 prep in,fed
R4018 T5605 T5604 pobj combination,in
R4019 T5606 T5605 prep with,combination
R4020 T5607 T5606 pobj vehicle,with
R4021 T5608 T5607 cc or,vehicle
R4022 T5609 T5607 conj GW501516,vehicle
R4023 T5610 T5586 prep for,fed
R4024 T5611 T5612 nummod 57,d
R4025 T5612 T5610 pobj d,for
R4026 T5613 T5586 punct .,fed
R4027 T5615 T5616 amod Total,RNA
R4028 T5616 T5617 nsubjpass RNA,probed
R4029 T5618 T5619 punct (,μg
R4030 T5619 T5616 parataxis μg,RNA
R4031 T5620 T5619 nummod 10,μg
R4032 T5621 T5622 punct /,lane
R4033 T5622 T5619 prep lane,μg
R4034 T5623 T5619 punct ),μg
R4035 T5624 T5616 acl prepared,RNA
R4036 T5625 T5624 prep from,prepared
R4037 T5626 T5627 det the,muscle
R4038 T5627 T5625 pobj muscle,from
R4039 T5628 T5627 compound gastrocnemius,muscle
R4040 T5629 T5617 auxpass was,probed
R4041 T5630 T5617 prep with,probed
R4042 T5631 T5632 amod indicated,probes
R4043 T5632 T5630 pobj probes,with
R4044 T5633 T5617 punct .,probed
R4045 T5635 T5636 punct (,B
R4046 T5636 T5637 meta B,calculated
R4047 T5638 T5636 punct ),B
R4048 T5639 T5640 amod Net,gain
R4049 T5640 T5637 nsubjpass gain,calculated
R4050 T5641 T5642 compound body,weight
R4051 T5642 T5640 compound weight,gain
R4052 T5643 T5640 prep for,gain
R4053 T5644 T5643 pobj mice,for
R4054 T5645 T5644 prep in,mice
R4055 T5646 T5645 punct (,in
R4056 T5647 T5645 pobj A,in
R4057 T5648 T5644 punct ),mice
R4058 T5649 T5640 prep after,gain
R4059 T5650 T5649 pobj treatment,after
R4060 T5651 T5637 auxpass was,calculated
R4061 T5652 T5637 prep for,calculated
R4062 T5653 T5654 amod individual,mice
R4063 T5654 T5652 pobj mice,for
R4064 T5655 T5637 cc and,calculated
R4065 T5656 T5637 conj averaged,calculated
R4066 T5657 T5637 punct .,calculated
R4067 T5659 T5660 amod Initial,weights
R4068 T5660 T5662 nsubj weights,were
R4069 T5661 T5660 compound body,weights
R4070 T5663 T5664 quantmod 28.54,1.04
R4071 T5664 T5666 nummod 1.04,g
R4072 T5665 T5664 punct ±,1.04
R4073 T5666 T5662 attr g,were
R4074 T5667 T5666 prep for,g
R4075 T5668 T5669 compound vehicle,group
R4076 T5669 T5667 pobj group,for
R4077 T5670 T5671 punct (,5
R4078 T5671 T5666 parataxis 5,g
R4079 T5672 T5671 nsubj n,5
R4080 T5673 T5671 punct =,5
R4081 T5674 T5671 punct ),5
R4082 T5675 T5666 cc and,g
R4083 T5676 T5677 quantmod 28.86,0.80
R4084 T5677 T5679 nummod 0.80,g
R4085 T5678 T5677 punct ±,0.80
R4086 T5679 T5666 conj g,g
R4087 T5680 T5679 prep for,g
R4088 T5681 T5682 compound GW501516,group
R4089 T5682 T5680 pobj group,for
R4090 T5683 T5684 punct (,5
R4091 T5684 T5679 parataxis 5,g
R4092 T5685 T5684 nsubj n,5
R4093 T5686 T5684 punct =,5
R4094 T5687 T5684 punct ),5
R4095 T5688 T5662 punct .,were
R4096 T5690 T5691 punct (,C
R4097 T5691 T5692 meta C,weights
R4098 T5693 T5691 punct ),C
R4099 T5694 T5692 amod Various,weights
R4100 T5695 T5692 compound tissue,weights
R4101 T5696 T5692 prep for,weights
R4102 T5697 T5696 pobj mice,for
R4103 T5698 T5697 prep in,mice
R4104 T5699 T5698 punct (,in
R4105 T5700 T5698 pobj A,in
R4106 T5701 T5698 punct ),in
R4107 T5702 T5692 prep after,weights
R4108 T5703 T5702 pobj treatment,after
R4109 T5704 T5692 punct .,weights
R4110 T5707 T5706 punct ", ",ifat
R4111 T5708 T5709 amod inguinal,fat
R4112 T5709 T5706 appos fat,ifat
R4113 T5710 T5706 punct ;,ifat
R4114 T5711 T5706 appos rdfat,ifat
R4115 T5712 T5711 punct ", ",rdfat
R4116 T5713 T5714 amod reproductive,fat
R4117 T5714 T5711 appos fat,rdfat
R4118 T5715 T5706 punct ;,ifat
R4119 T5716 T5706 appos retrofat,ifat
R4120 T5717 T5716 punct ", ",retrofat
R4121 T5718 T5719 amod retroperitoneal,fat
R4122 T5719 T5716 appos fat,retrofat
R4123 T5720 T5706 punct .,ifat
R4124 T5722 T5723 punct (,D
R4125 T5723 T5724 meta D,test
R4126 T5725 T5723 punct ),D
R4127 T5726 T5727 compound Glucose,tolerance
R4128 T5727 T5724 compound tolerance,test
R4129 T5728 T5724 punct .,test
R4130 T5730 T5731 nsubjpass Mice,fasted
R4131 T5732 T5730 prep in,Mice
R4132 T5733 T5732 punct (,in
R4133 T5734 T5732 pobj A,in
R4134 T5735 T5730 punct ),Mice
R4135 T5736 T5730 prep after,Mice
R4136 T5737 T5736 pobj treatment,after
R4137 T5738 T5731 auxpass were,fasted
R4138 T5739 T5731 prep for,fasted
R4139 T5740 T5741 nummod 6,h
R4140 T5741 T5739 pobj h,for
R4141 T5742 T5731 cc and,fasted
R4142 T5743 T5744 advmod then,injected
R4143 T5744 T5731 conj injected,fasted
R4144 T5745 T5744 prep with,injected
R4145 T5746 T5745 pobj glucose,with
R4146 T5747 T5746 prep at,glucose
R4147 T5748 T5749 det a,concentration
R4148 T5749 T5747 pobj concentration,at
R4149 T5750 T5749 prep of,concentration
R4150 T5751 T5750 pobj 1g,of
R4151 T5752 T5753 punct /,weight
R4152 T5753 T5751 prep weight,1g
R4153 T5754 T5753 compound kg,weight
R4154 T5755 T5753 compound body,weight
R4155 T5756 T5731 punct .,fasted
R4156 T5758 T5759 compound Blood,glucose
R4157 T5759 T5760 compound glucose,levels
R4158 T5760 T5761 nsubjpass levels,measured
R4159 T5762 T5761 auxpass were,measured
R4160 T5763 T5761 advmod then,measured
R4161 T5764 T5761 advmod periodically,measured
R4162 T5765 T5761 prep over,measured
R4163 T5766 T5767 nummod 2,h
R4164 T5767 T5765 pobj h,over
R4165 T5768 T5761 punct .,measured