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PMC:509305 / 2586-3737 JSONTXT 5 Projects

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Id Subject Object Predicate Lexical cue
T2948 0-3 DT denotes The
T2950 4-8 RBS denotes best
T2952 8-9 HYPH denotes -
T2951 9-16 VBN denotes studied
T2949 17-24 NNS denotes strains
T2954 25-27 IN denotes of
T2955 28-32 NNS denotes mice
T2956 33-37 WDT denotes that
T2958 38-51 RB denotes spontaneously
T2957 52-59 VBP denotes develop
T2959 60-61 DT denotes a
T2961 62-67 NN denotes lupus
T2963 67-68 HYPH denotes -
T2962 68-72 JJ denotes like
T2960 73-82 NN denotes pathology
T2953 83-86 VBP denotes are
T2964 87-90 DT denotes the
T2966 91-94 NNP denotes New
T2967 95-102 NNP denotes Zealand
T2968 103-108 NN denotes Black
T2969 108-109 HYPH denotes /
T2970 109-112 NNP denotes New
T2971 113-120 NNP denotes Zealand
T2972 121-126 NN denotes White
T2973 127-133 NN denotes hybrid
T2965 134-140 NN denotes strain
T2974 141-142 -LRB- denotes (
T2976 142-145 NN denotes NZB
T2977 145-146 HYPH denotes /
T2975 146-149 NN denotes WF1
T2978 149-150 -RRB- denotes )
T2979 150-151 : denotes ;
T2980 152-155 DT denotes the
T2982 156-159 NN denotes MRL
T2984 159-160 HYPH denotes /
T2983 160-162 NN denotes Mp
T2985 163-166 NN denotes lpr
T2987 166-167 HYPH denotes /
T2986 167-170 NN denotes lpr
T2981 171-177 NN denotes strain
T2988 177-179 , denotes ,
T2989 179-184 WDT denotes which
T2990 185-192 VBZ denotes carries
T2991 193-196 DT denotes the
T2993 197-200 NN denotes lpr
T2992 201-209 NN denotes mutation
T2994 210-212 IN denotes of
T2995 213-216 DT denotes the
T2997 217-220 NN denotes FAS
T2998 221-229 NN denotes receptor
T2996 230-234 NN denotes gene
T2999 234-235 : denotes ;
T3000 236-239 CC denotes and
T3001 240-243 DT denotes the
T3003 244-248 NN denotes BXSB
T3002 249-255 NN denotes strain
T3004 255-257 , denotes ,
T3005 257-262 WDT denotes which
T3006 263-270 VBZ denotes carries
T3007 271-274 DT denotes the
T3009 275-276 NN denotes Y
T3010 277-287 NN denotes chromosome
T3012 288-298 JJ denotes autoimmune
T3011 299-310 NN denotes accelerator
T3013 311-312 -LRB- denotes (
T3014 312-315 NNP denotes Yaa
T3015 315-316 -RRB- denotes )
T3008 317-321 NN denotes gene
T3016 322-323 -LRB- denotes (
T3017 323-337 NNP denotes Theofilopoulos
T3018 338-341 CC denotes and
T3019 342-347 NNP denotes Dixon
T3020 348-352 CD denotes 1985
T3021 352-353 -RRB- denotes )
T3022 353-354 . denotes .
T3023 354-484 sentence denotes Extensive genetic mapping studies in all three strains have identified multiple intervals associated with disease susceptibility.
T3024 355-364 JJ denotes Extensive
T3026 365-372 JJ denotes genetic
T3027 373-380 NN denotes mapping
T3025 381-388 NNS denotes studies
T3029 389-391 IN denotes in
T3030 392-395 DT denotes all
T3032 396-401 CD denotes three
T3031 402-409 NNS denotes strains
T3033 410-414 VBP denotes have
T3028 415-425 VBN denotes identified
T3034 426-434 JJ denotes multiple
T3035 435-444 NNS denotes intervals
T3036 445-455 VBN denotes associated
T3037 456-460 IN denotes with
T3038 461-468 NN denotes disease
T3039 469-483 NN denotes susceptibility
T3040 483-484 . denotes .
T3041 484-725 sentence denotes Interestingly, the majority of the intervals detected are strain-specific, confirming the genetic complexity of the disease and indicating the presence of extensive heterogeneity in the genes contributing to the pathogenesis of the disease.
T3042 485-498 RB denotes Interestingly
T3044 498-500 , denotes ,
T3045 500-503 DT denotes the
T3046 504-512 NN denotes majority
T3047 513-515 IN denotes of
T3048 516-519 DT denotes the
T3049 520-529 NNS denotes intervals
T3050 530-538 VBN denotes detected
T3043 539-542 VBP denotes are
T3051 543-549 NN denotes strain
T3053 549-550 HYPH denotes -
T3052 550-558 JJ denotes specific
T3054 558-560 , denotes ,
T3055 560-570 VBG denotes confirming
T3056 571-574 DT denotes the
T3058 575-582 JJ denotes genetic
T3057 583-593 NN denotes complexity
T3059 594-596 IN denotes of
T3060 597-600 DT denotes the
T3061 601-608 NN denotes disease
T3062 609-612 CC denotes and
T3063 613-623 VBG denotes indicating
T3064 624-627 DT denotes the
T3065 628-636 NN denotes presence
T3066 637-639 IN denotes of
T3067 640-649 JJ denotes extensive
T3068 650-663 NN denotes heterogeneity
T3069 664-666 IN denotes in
T3070 667-670 DT denotes the
T3071 671-676 NNS denotes genes
T3072 677-689 VBG denotes contributing
T3073 690-692 IN denotes to
T3074 693-696 DT denotes the
T3075 697-709 NN denotes pathogenesis
T3076 710-712 IN denotes of
T3077 713-716 DT denotes the
T3078 717-724 NN denotes disease
T3079 724-725 . denotes .
T3080 725-918 sentence denotes However, some susceptibility loci have been mapped to similar chromosome locations in different strains, suggesting that at least some susceptibility may be shared amongst lupus-prone strains.
T3081 726-733 RB denotes However
T3083 733-735 , denotes ,
T3084 735-739 DT denotes some
T3086 740-754 NN denotes susceptibility
T3085 755-759 NNS denotes loci
T3087 760-764 VBP denotes have
T3088 765-769 VBN denotes been
T3082 770-776 VBN denotes mapped
T3089 777-779 IN denotes to
T3090 780-787 JJ denotes similar
T3092 788-798 NN denotes chromosome
T3091 799-808 NNS denotes locations
T3093 809-811 IN denotes in
T3094 812-821 JJ denotes different
T3095 822-829 NNS denotes strains
T3096 829-831 , denotes ,
T3097 831-841 VBG denotes suggesting
T3098 842-846 IN denotes that
T3100 847-849 RB denotes at
T3101 850-855 RBS denotes least
T3103 856-860 DT denotes some
T3102 861-875 NN denotes susceptibility
T3104 876-879 MD denotes may
T3105 880-882 VB denotes be
T3099 883-889 VBN denotes shared
T3106 890-897 IN denotes amongst
T3107 898-903 NN denotes lupus
T3109 903-904 HYPH denotes -
T3108 904-909 JJ denotes prone
T3110 910-917 NNS denotes strains
T3111 917-918 . denotes .
T3112 918-1151 sentence denotes Amongst these shared susceptibility loci, the most striking are loci on distal Chromosome 1, for which important contributing genes have been found in New Zealand and BXSB models (Theofilopoulos and Kono 1999; Wakeland et al. 2001).
T3113 919-926 IN denotes Amongst
T3115 927-932 DT denotes these
T3117 933-939 VBN denotes shared
T3118 940-954 NN denotes susceptibility
T3116 955-959 NNS denotes loci
T3119 959-961 , denotes ,
T3120 961-964 DT denotes the
T3122 965-969 RBS denotes most
T3121 970-978 JJ denotes striking
T3114 979-982 VBP denotes are
T3123 983-987 NNS denotes loci
T3124 988-990 IN denotes on
T3125 991-997 JJ denotes distal
T3126 998-1008 NN denotes Chromosome
T3127 1009-1010 CD denotes 1
T3128 1010-1012 , denotes ,
T3129 1012-1015 IN denotes for
T3131 1016-1021 WDT denotes which
T3132 1022-1031 JJ denotes important
T3134 1032-1044 VBG denotes contributing
T3133 1045-1050 NNS denotes genes
T3135 1051-1055 VBP denotes have
T3136 1056-1060 VBN denotes been
T3130 1061-1066 VBN denotes found
T3137 1067-1069 IN denotes in
T3138 1070-1073 NNP denotes New
T3139 1074-1081 NNP denotes Zealand
T3141 1082-1085 CC denotes and
T3142 1086-1090 NN denotes BXSB
T3140 1091-1097 NNS denotes models
T3143 1098-1099 -LRB- denotes (
T3144 1099-1113 NNP denotes Theofilopoulos
T3145 1114-1117 CC denotes and
T3146 1118-1122 NNP denotes Kono
T3147 1123-1127 CD denotes 1999
T3148 1127-1128 : denotes ;
T3149 1129-1137 NNP denotes Wakeland
T3150 1138-1140 FW denotes et
T3151 1141-1144 FW denotes al.
T3152 1145-1149 CD denotes 2001
T3153 1149-1150 -RRB- denotes )
T3154 1150-1151 . denotes .
R330 T2948 T2949 det The,strains
R332 T2949 T2953 nsubj strains,are
R333 T2950 T2951 advmod best,studied
R334 T2951 T2949 amod studied,strains
R336 T2952 T2951 punct -,studied
R337 T2954 T2949 prep of,strains
R339 T2955 T2954 pobj mice,of
R340 T2956 T2957 dep that,develop
R342 T2957 T2955 relcl develop,mice
R343 T2958 T2957 advmod spontaneously,develop
R345 T2959 T2960 det a,pathology
R346 T2960 T2957 dobj pathology,develop
R347 T2961 T2962 npadvmod lupus,like
R349 T2962 T2960 amod like,pathology
R350 T2963 T2962 punct -,like
R352 T2964 T2965 det the,strain
R353 T2965 T2953 attr strain,are
R354 T2966 T2967 nmod New,Zealand
R356 T2967 T2968 nmod Zealand,Black
R357 T2968 T2965 nmod Black,strain
R358 T2969 T2968 punct /,Black
R360 T2970 T2971 compound New,Zealand
R361 T2971 T2972 compound Zealand,White
R362 T2972 T2968 appos White,Black
R363 T2973 T2965 compound hybrid,strain
R364 T2974 T2975 punct (,WF1
R365 T2975 T2965 parataxis WF1,strain
R366 T2976 T2975 compound NZB,WF1
R367 T2977 T2975 punct /,WF1
R369 T2978 T2975 punct ),WF1
R370 T2979 T2965 punct ;,strain
R371 T2980 T2981 det the,strain
R374 T2981 T2965 conj strain,strain
R376 T2982 T2983 compound MRL,Mp
R377 T2983 T2981 compound Mp,strain
R378 T2984 T2983 punct /,Mp
R380 T2985 T2986 compound lpr,lpr
R381 T2986 T2981 compound lpr,strain
R382 T2987 T2986 punct /,lpr
R384 T2988 T2981 punct ", ",strain
R385 T2989 T2990 dep which,carries
R386 T2990 T2981 relcl carries,strain
R388 T2991 T2992 det the,mutation
R390 T2992 T2990 dobj mutation,carries
R391 T2993 T2992 compound lpr,mutation
R392 T2994 T2992 prep of,mutation
R393 T2995 T2996 det the,gene
R396 T2996 T2994 pobj gene,of
R397 T2997 T2998 compound FAS,receptor
R398 T2998 T2996 compound receptor,gene
R399 T2999 T2981 punct ;,strain
R401 T3000 T2981 cc and,strain
R402 T3001 T3002 det the,strain
R403 T3002 T2981 conj strain,strain
R405 T3003 T3002 compound BXSB,strain
R406 T3004 T3002 punct ", ",strain
R407 T3005 T3006 dep which,carries
R409 T3006 T3002 relcl carries,strain
R410 T3007 T3008 det the,gene
R411 T3008 T3006 dobj gene,carries
R413 T3009 T3010 nmod Y,chromosome
R414 T3010 T3011 nmod chromosome,accelerator
R415 T3011 T3008 nmod accelerator,gene
R416 T3012 T3011 amod autoimmune,accelerator
R417 T3013 T3011 punct (,accelerator
R418 T3014 T3011 appos Yaa,accelerator
R420 T3015 T3011 punct ),accelerator
R421 T3016 T3017 punct (,Theofilopoulos
R422 T3017 T3008 meta Theofilopoulos,gene
R424 T3018 T3017 cc and,Theofilopoulos
R425 T3019 T3017 conj Dixon,Theofilopoulos
R426 T3020 T3019 nummod 1985,Dixon
R428 T3021 T3019 punct ),Dixon
R429 T3022 T2953 punct .,are
R431 T3024 T3025 amod Extensive,studies
R432 T3025 T3028 nsubj studies,identified
R434 T3026 T3027 amod genetic,mapping
R435 T3027 T3025 compound mapping,studies
R437 T3029 T3025 prep in,studies
R438 T3030 T3031 det all,strains
R442 T3031 T3029 pobj strains,in
R443 T3032 T3031 nummod three,strains
R445 T3033 T3028 aux have,identified
R446 T3034 T3035 amod multiple,intervals
R448 T3035 T3028 dobj intervals,identified
R449 T3036 T3035 acl associated,intervals
R451 T3037 T3036 prep with,associated
R452 T3038 T3039 compound disease,susceptibility
R453 T3039 T3037 pobj susceptibility,with
R455 T3040 T3028 punct .,identified
R457 T3042 T3043 advmod Interestingly,are
R458 T3044 T3043 punct ", ",are
R460 T3045 T3046 det the,majority
R461 T3046 T3043 nsubj majority,are
R462 T3047 T3046 prep of,majority
R464 T3048 T3049 det the,intervals
R465 T3049 T3047 pobj intervals,of
R467 T3050 T3049 acl detected,intervals
R468 T3051 T3052 npadvmod strain,specific
R469 T3052 T3043 acomp specific,are
R470 T3053 T3052 punct -,specific
R471 T3054 T3043 punct ", ",are
R472 T3055 T3043 advcl confirming,are
R474 T3056 T3057 det the,complexity
R475 T3057 T3055 dobj complexity,confirming
R476 T3058 T3057 amod genetic,complexity
R478 T3059 T3057 prep of,complexity
R479 T3060 T3061 det the,disease
R480 T3061 T3059 pobj disease,of
R482 T3062 T3055 cc and,confirming
R483 T3063 T3055 conj indicating,confirming
R484 T3064 T3065 det the,presence
R486 T3065 T3063 dobj presence,indicating
R487 T3066 T3065 prep of,presence
R491 T3067 T3068 amod extensive,heterogeneity
R493 T3068 T3066 pobj heterogeneity,of
R494 T3069 T3063 prep in,indicating
R496 T3070 T3071 det the,genes
R497 T3071 T3069 pobj genes,in
R499 T3072 T3071 acl contributing,genes
R500 T3073 T3072 prep to,contributing
R501 T3074 T3075 det the,pathogenesis
R503 T3075 T3073 pobj pathogenesis,to
R504 T3076 T3075 prep of,pathogenesis
R505 T3077 T3078 det the,disease
R507 T3078 T3076 pobj disease,of
R508 T3079 T3043 punct .,are
R510 T3081 T3082 advmod However,mapped
R512 T3083 T3082 punct ", ",mapped
R513 T3084 T3085 det some,loci
R514 T3085 T3082 nsubjpass loci,mapped
R516 T3086 T3085 compound susceptibility,loci
R517 T3087 T3082 aux have,mapped
R519 T3088 T3082 auxpass been,mapped
R520 T3089 T3082 prep to,mapped
R521 T3090 T3091 amod similar,locations
R522 T3091 T3089 pobj locations,to
R523 T3092 T3091 compound chromosome,locations
R524 T3093 T3091 prep in,locations
R525 T3094 T3095 amod different,strains
R527 T3095 T3093 pobj strains,in
R528 T3096 T3082 punct ", ",mapped
R529 T3097 T3082 advcl suggesting,mapped
R531 T3098 T3099 mark that,shared
R532 T3099 T3097 ccomp shared,suggesting
R533 T3100 T3101 advmod at,least
R535 T3101 T3102 advmod least,susceptibility
R536 T3102 T3099 nsubjpass susceptibility,shared
R537 T3103 T3102 det some,susceptibility
R539 T3104 T3099 aux may,shared
R540 T3105 T3099 auxpass be,shared
R541 T3106 T3099 prep amongst,shared
R543 T3107 T3108 npadvmod lupus,prone
R544 T3108 T3110 amod prone,strains
R546 T3109 T3108 punct -,prone
R547 T3110 T3106 pobj strains,amongst
R548 T3111 T3082 punct .,mapped
R550 T3113 T3114 prep Amongst,are
R552 T3115 T3116 det these,loci
R553 T3116 T3113 pobj loci,Amongst
R555 T3117 T3116 amod shared,loci
R556 T3118 T3116 compound susceptibility,loci
R557 T3119 T3114 punct ", ",are
R559 T3120 T3121 det the,striking
R560 T3121 T3114 nsubj striking,are
R562 T3122 T3121 advmod most,striking
R563 T3123 T3114 attr loci,are
R564 T3124 T3123 prep on,loci
R566 T3125 T3126 amod distal,Chromosome
R567 T3126 T3124 pobj Chromosome,on
R568 T3127 T3126 nummod 1,Chromosome
R570 T3128 T3123 punct ", ",loci
R571 T3129 T3130 prep for,found
R572 T3130 T3123 relcl found,loci
R573 T3131 T3129 pobj which,for
R574 T3132 T3133 amod important,genes
R575 T3137 T3130 prep in,found
R576 T3133 T3130 nsubjpass genes,found
R577 T3134 T3133 amod contributing,genes
R578 T3138 T3139 nmod New,Zealand
R579 T3135 T3130 aux have,found
R580 T3136 T3130 auxpass been,found
R581 T3139 T3140 nmod Zealand,models
R582 T3140 T3137 pobj models,in
R583 T3141 T3139 cc and,Zealand
R585 T3142 T3139 conj BXSB,Zealand
R588 T3143 T3144 punct (,Theofilopoulos
R591 T3144 T3130 meta Theofilopoulos,found
R594 T3145 T3144 cc and,Theofilopoulos
R598 T3146 T3144 conj Kono,Theofilopoulos
R602 T3147 T3146 nummod 1999,Kono
R606 T3148 T3146 punct ;,Kono
R610 T3149 T3146 conj Wakeland,Kono
R614 T3150 T3149 nmod et,Wakeland
R616 T3151 T3149 nmod al.,Wakeland
R619 T3152 T3149 nummod 2001,Wakeland
R623 T3153 T3149 punct ),Wakeland
R630 T3154 T3114 punct .,are