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PMC:441373 / 544-1261 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T262 0-7 NNS denotes Results
T263 7-154 sentence denotes We have performed an extensive database analysis to determine the genomic and cDNA sequences of the TACCs from phylogenetically diverse organisms.
T264 8-10 PRP denotes We
T266 11-15 VBP denotes have
T265 16-25 VBN denotes performed
T267 26-28 DT denotes an
T269 29-38 JJ denotes extensive
T270 39-47 NN denotes database
T268 48-56 NN denotes analysis
T271 57-59 TO denotes to
T272 60-69 VB denotes determine
T273 70-73 DT denotes the
T275 74-81 JJ denotes genomic
T276 82-85 CC denotes and
T277 86-90 NN denotes cDNA
T274 91-100 NNS denotes sequences
T278 101-103 IN denotes of
T279 104-107 DT denotes the
T280 108-113 NNS denotes TACCs
T281 114-118 IN denotes from
T282 119-135 RB denotes phylogenetically
T283 136-143 JJ denotes diverse
T284 144-153 NNS denotes organisms
T285 153-154 . denotes .
T286 154-407 sentence denotes This analysis has determined the phylogenetic relationship of the TACC proteins to other coiled coil proteins, the resolution of the placement of the rabbit TACC4 as the orthologue of human TACC3, and RHAMM as a distinct family of coiled coil proteins.
T287 155-159 DT denotes This
T288 160-168 NN denotes analysis
T290 169-172 VBZ denotes has
T289 173-183 VBN denotes determined
T291 184-187 DT denotes the
T293 188-200 JJ denotes phylogenetic
T292 201-213 NN denotes relationship
T294 214-216 IN denotes of
T295 217-220 DT denotes the
T297 221-225 NN denotes TACC
T296 226-234 NN denotes proteins
T298 235-237 IN denotes to
T299 238-243 JJ denotes other
T301 244-250 VBN denotes coiled
T302 251-255 NN denotes coil
T300 256-264 NN denotes proteins
T303 264-266 , denotes ,
T304 266-269 DT denotes the
T305 270-280 NN denotes resolution
T306 281-283 IN denotes of
T307 284-287 DT denotes the
T308 288-297 NN denotes placement
T309 298-300 IN denotes of
T310 301-304 DT denotes the
T312 305-311 NN denotes rabbit
T311 312-317 NN denotes TACC4
T313 318-320 IN denotes as
T314 321-324 DT denotes the
T315 325-335 NN denotes orthologue
T316 336-338 IN denotes of
T317 339-344 JJ denotes human
T318 345-350 NN denotes TACC3
T319 350-352 , denotes ,
T320 352-355 CC denotes and
T321 356-361 NN denotes RHAMM
T322 362-364 IN denotes as
T323 365-366 DT denotes a
T325 367-375 JJ denotes distinct
T324 376-382 NN denotes family
T326 383-385 IN denotes of
T327 386-392 VBN denotes coiled
T328 393-397 NN denotes coil
T329 398-406 NN denotes proteins
T330 406-407 . denotes .
T331 407-567 sentence denotes We have also extended the analysis of the TACCs to the interaction databases of C. elegans and D. melanogaster to identify potentially novel TACC interactions.
T332 408-410 PRP denotes We
T334 411-415 VBP denotes have
T335 416-420 RB denotes also
T333 421-429 VBN denotes extended
T336 430-433 DT denotes the
T337 434-442 NN denotes analysis
T338 443-445 IN denotes of
T339 446-449 DT denotes the
T340 450-455 NNS denotes TACCs
T341 456-458 IN denotes to
T342 459-462 DT denotes the
T344 463-474 NN denotes interaction
T343 475-484 NNS denotes databases
T345 485-487 IN denotes of
T346 488-490 NNP denotes C.
T347 491-498 NNP denotes elegans
T348 499-502 CC denotes and
T349 503-505 NNP denotes D.
T350 506-518 NNP denotes melanogaster
T351 519-521 TO denotes to
T352 522-530 VB denotes identify
T353 531-542 RB denotes potentially
T354 543-548 JJ denotes novel
T356 549-553 NN denotes TACC
T355 554-566 NNS denotes interactions
T357 566-567 . denotes .
T358 567-717 sentence denotes The validity of this modeling was confirmed independently by the demonstration of direct binding of human TACC2 to the nuclear hormone receptor RXRβ.
T359 568-571 DT denotes The
T360 572-580 NN denotes validity
T362 581-583 IN denotes of
T363 584-588 DT denotes this
T364 589-597 NN denotes modeling
T365 598-601 VBD denotes was
T361 602-611 VBN denotes confirmed
T366 612-625 RB denotes independently
T367 626-628 IN denotes by
T368 629-632 DT denotes the
T369 633-646 NN denotes demonstration
T370 647-649 IN denotes of
T371 650-656 JJ denotes direct
T372 657-664 NN denotes binding
T373 665-667 IN denotes of
T374 668-673 JJ denotes human
T375 674-679 NN denotes TACC2
T376 680-682 IN denotes to
T377 683-686 DT denotes the
T379 687-694 JJ denotes nuclear
T380 695-702 NN denotes hormone
T378 703-711 NN denotes receptor
T381 712-716 NN denotes RXRβ
T382 716-717 . denotes .
R100 T288 T289 nsubj analysis,determined
R101 T290 T289 aux has,determined
R102 T291 T292 det the,relationship
R103 T292 T289 dobj relationship,determined
R104 T293 T292 amod phylogenetic,relationship
R105 T294 T292 prep of,relationship
R106 T295 T296 det the,proteins
R107 T296 T294 pobj proteins,of
R108 T297 T296 compound TACC,proteins
R109 T298 T292 prep to,relationship
R110 T299 T300 amod other,proteins
R111 T300 T298 pobj proteins,to
R112 T301 T302 amod coiled,coil
R113 T302 T300 compound coil,proteins
R114 T303 T292 punct ", ",relationship
R115 T304 T305 det the,resolution
R116 T305 T292 conj resolution,relationship
R117 T306 T305 prep of,resolution
R118 T307 T308 det the,placement
R119 T308 T306 pobj placement,of
R120 T309 T308 prep of,placement
R121 T310 T311 det the,TACC4
R122 T311 T309 pobj TACC4,of
R123 T312 T311 compound rabbit,TACC4
R124 T313 T308 prep as,placement
R125 T314 T315 det the,orthologue
R126 T315 T313 pobj orthologue,as
R127 T316 T315 prep of,orthologue
R128 T317 T318 amod human,TACC3
R129 T318 T316 pobj TACC3,of
R130 T319 T305 punct ", ",resolution
R131 T320 T305 cc and,resolution
R132 T321 T305 conj RHAMM,resolution
R133 T322 T321 prep as,RHAMM
R134 T323 T324 det a,family
R135 T324 T322 pobj family,as
R136 T325 T324 amod distinct,family
R137 T326 T324 prep of,family
R138 T327 T328 amod coiled,coil
R139 T328 T329 compound coil,proteins
R140 T329 T326 pobj proteins,of
R141 T330 T289 punct .,determined
R142 T332 T333 nsubj We,extended
R143 T334 T333 aux have,extended
R144 T335 T333 advmod also,extended
R145 T336 T337 det the,analysis
R146 T337 T333 dobj analysis,extended
R147 T338 T337 prep of,analysis
R148 T339 T340 det the,TACCs
R149 T340 T338 pobj TACCs,of
R150 T341 T333 prep to,extended
R151 T342 T343 det the,databases
R152 T343 T341 pobj databases,to
R153 T344 T343 compound interaction,databases
R154 T345 T343 prep of,databases
R155 T346 T347 compound C.,elegans
R156 T347 T345 pobj elegans,of
R157 T348 T347 cc and,elegans
R158 T349 T350 compound D.,melanogaster
R159 T350 T347 conj melanogaster,elegans
R160 T351 T352 aux to,identify
R161 T352 T333 advcl identify,extended
R162 T353 T354 advmod potentially,novel
R163 T354 T355 amod novel,interactions
R164 T355 T352 dobj interactions,identify
R165 T356 T355 compound TACC,interactions
R166 T357 T333 punct .,extended
R167 T359 T360 det The,validity
R168 T360 T361 nsubjpass validity,confirmed
R169 T362 T360 prep of,validity
R170 T363 T364 det this,modeling
R171 T364 T362 pobj modeling,of
R172 T365 T361 auxpass was,confirmed
R173 T366 T361 advmod independently,confirmed
R174 T367 T361 prep by,confirmed
R175 T368 T369 det the,demonstration
R176 T369 T367 pobj demonstration,by
R177 T370 T369 prep of,demonstration
R178 T371 T372 amod direct,binding
R179 T372 T370 pobj binding,of
R180 T373 T372 prep of,binding
R181 T374 T375 amod human,TACC2
R182 T375 T373 pobj TACC2,of
R183 T376 T372 prep to,binding
R184 T377 T378 det the,receptor
R185 T378 T376 pobj receptor,to
R186 T379 T378 amod nuclear,receptor
R187 T380 T378 compound hormone,receptor
R188 T381 T378 appos RXRβ,receptor
R189 T382 T361 punct .,confirmed
R78 T264 T265 nsubj We,performed
R79 T266 T265 aux have,performed
R80 T267 T268 det an,analysis
R81 T268 T265 dobj analysis,performed
R82 T269 T268 amod extensive,analysis
R83 T270 T268 compound database,analysis
R84 T271 T272 aux to,determine
R85 T272 T265 advcl determine,performed
R86 T273 T274 det the,sequences
R87 T274 T272 dobj sequences,determine
R88 T275 T274 amod genomic,sequences
R89 T276 T275 cc and,genomic
R90 T277 T275 conj cDNA,genomic
R91 T278 T274 prep of,sequences
R92 T279 T280 det the,TACCs
R93 T280 T278 pobj TACCs,of
R94 T281 T280 prep from,TACCs
R95 T282 T283 advmod phylogenetically,diverse
R96 T283 T284 amod diverse,organisms
R97 T284 T281 pobj organisms,from
R98 T285 T265 punct .,performed
R99 T287 T288 det This,analysis