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PMC:441373 / 4915-9990 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1593 0-2 FW denotes In
T1594 3-9 FW denotes silico
T1595 10-24 NN denotes identification
T1596 25-27 IN denotes of
T1597 28-32 NN denotes TACC
T1599 33-39 NN denotes family
T1598 40-47 NNS denotes members
T1600 48-52 IN denotes from
T1601 53-63 NN denotes vertebrate
T1603 64-67 CC denotes and
T1604 68-80 NN denotes invertebrate
T1602 81-89 NNS denotes lineages
T1605 89-338 sentence denotes Sequence similarity searches of the publicly available genome databases with the BLAST and TBLAST programs were performed to identify TACC and RHAMM orthologues, and other members of the coiled coil superfamily in a diverse set of species (Fig. 1).
T1606 90-98 NN denotes Sequence
T1607 99-109 NN denotes similarity
T1608 110-118 NNS denotes searches
T1610 119-121 IN denotes of
T1611 122-125 DT denotes the
T1613 126-134 RB denotes publicly
T1614 135-144 JJ denotes available
T1615 145-151 NN denotes genome
T1612 152-161 NNS denotes databases
T1616 162-166 IN denotes with
T1617 167-170 DT denotes the
T1619 171-176 NN denotes BLAST
T1620 177-180 CC denotes and
T1621 181-187 NN denotes TBLAST
T1618 188-196 NNS denotes programs
T1622 197-201 VBD denotes were
T1609 202-211 VBN denotes performed
T1623 212-214 TO denotes to
T1624 215-223 VB denotes identify
T1625 224-228 NN denotes TACC
T1627 229-232 CC denotes and
T1628 233-238 NN denotes RHAMM
T1626 239-250 NNS denotes orthologues
T1629 250-252 , denotes ,
T1630 252-255 CC denotes and
T1631 256-261 JJ denotes other
T1632 262-269 NNS denotes members
T1633 270-272 IN denotes of
T1634 273-276 DT denotes the
T1636 277-283 VBN denotes coiled
T1637 284-288 NN denotes coil
T1635 289-300 NN denotes superfamily
T1638 301-303 IN denotes in
T1639 304-305 DT denotes a
T1641 306-313 JJ denotes diverse
T1640 314-317 NN denotes set
T1642 318-320 IN denotes of
T1643 321-328 NNS denotes species
T1644 329-330 -LRB- denotes (
T1645 330-334 NN denotes Fig.
T1646 335-336 CD denotes 1
T1647 336-337 -RRB- denotes )
T1648 337-338 . denotes .
T1649 338-461 sentence denotes This identified the complete sequence of the TACC genes in representatives of five major phylogenetically distinct clades.
T1650 339-343 DT denotes This
T1651 344-354 VBD denotes identified
T1652 355-358 DT denotes the
T1654 359-367 JJ denotes complete
T1653 368-376 NN denotes sequence
T1655 377-379 IN denotes of
T1656 380-383 DT denotes the
T1658 384-388 NN denotes TACC
T1657 389-394 NNS denotes genes
T1659 395-397 IN denotes in
T1660 398-413 NNS denotes representatives
T1661 414-416 IN denotes of
T1662 417-421 CD denotes five
T1664 422-427 JJ denotes major
T1665 428-444 RB denotes phylogenetically
T1666 445-453 JJ denotes distinct
T1663 454-460 NNS denotes clades
T1667 460-461 . denotes .
T1668 461-595 sentence denotes Where possible, the construction of the TACC sequences from these organisms was also confirmed by the analysis of the cDNA databases.
T1669 462-467 WRB denotes Where
T1670 468-476 JJ denotes possible
T1672 476-478 , denotes ,
T1673 478-481 DT denotes the
T1674 482-494 NN denotes construction
T1675 495-497 IN denotes of
T1676 498-501 DT denotes the
T1678 502-506 NN denotes TACC
T1677 507-516 NNS denotes sequences
T1679 517-521 IN denotes from
T1680 522-527 DT denotes these
T1681 528-537 NNS denotes organisms
T1682 538-541 VBD denotes was
T1683 542-546 RB denotes also
T1671 547-556 VBN denotes confirmed
T1684 557-559 IN denotes by
T1685 560-563 DT denotes the
T1686 564-572 NN denotes analysis
T1687 573-575 IN denotes of
T1688 576-579 DT denotes the
T1690 580-584 NN denotes cDNA
T1689 585-594 NNS denotes databases
T1691 594-595 . denotes .
T1692 595-839 sentence denotes Several partial sequences in other vertebrate species, the echinodermate Strongylocentrotus purpuratus and the protostome insect Anopheles gambiae were also identified, suggesting an ancient conservation of the TACC genes in metazoan lineages.
T1693 596-603 JJ denotes Several
T1695 604-611 JJ denotes partial
T1694 612-621 NNS denotes sequences
T1697 622-624 IN denotes in
T1698 625-630 JJ denotes other
T1700 631-641 NN denotes vertebrate
T1699 642-649 NNS denotes species
T1701 649-651 , denotes ,
T1702 651-654 DT denotes the
T1703 655-668 JJ denotes echinodermate
T1704 669-687 NNP denotes Strongylocentrotus
T1705 688-698 NNP denotes purpuratus
T1706 699-702 CC denotes and
T1707 703-706 DT denotes the
T1709 707-717 NN denotes protostome
T1708 718-724 NN denotes insect
T1710 725-734 NNP denotes Anopheles
T1711 735-742 NNP denotes gambiae
T1712 743-747 VBD denotes were
T1713 748-752 RB denotes also
T1696 753-763 VBN denotes identified
T1714 763-765 , denotes ,
T1715 765-775 VBG denotes suggesting
T1716 776-778 DT denotes an
T1718 779-786 JJ denotes ancient
T1717 787-799 NN denotes conservation
T1719 800-802 IN denotes of
T1720 803-806 DT denotes the
T1722 807-811 NN denotes TACC
T1721 812-817 NNS denotes genes
T1723 818-820 IN denotes in
T1724 821-829 NN denotes metazoan
T1725 830-838 NNS denotes lineages
T1726 838-839 . denotes .
T1727 839-1003 sentence denotes However, due to the relative infancy of the cDNA/genome projects for these latter organisms, complete characterization of these TACC genes could not be undertaken.
T1728 840-847 RB denotes However
T1730 847-849 , denotes ,
T1731 849-852 IN denotes due
T1732 853-855 IN denotes to
T1733 856-859 DT denotes the
T1735 860-868 JJ denotes relative
T1734 869-876 NN denotes infancy
T1736 877-879 IN denotes of
T1737 880-883 DT denotes the
T1739 884-888 NN denotes cDNA
T1741 888-889 HYPH denotes /
T1740 889-895 NN denotes genome
T1738 896-904 NNS denotes projects
T1742 905-908 IN denotes for
T1743 909-914 DT denotes these
T1745 915-921 JJ denotes latter
T1744 922-931 NNS denotes organisms
T1746 931-933 , denotes ,
T1747 933-941 JJ denotes complete
T1748 942-958 NN denotes characterization
T1749 959-961 IN denotes of
T1750 962-967 DT denotes these
T1752 968-972 NN denotes TACC
T1751 973-978 NNS denotes genes
T1753 979-984 MD denotes could
T1754 985-988 RB denotes not
T1755 989-991 VB denotes be
T1729 992-1002 VBN denotes undertaken
T1756 1002-1003 . denotes .
T1757 1003-1311 sentence denotes No conclusion could be made about the existence of TACC-like sequence in non-bilaterian metazoans, such as Cnidaria or Porifera, due to the paucity of sequence information for these organisms, and additional definitive sequences with a defined TACC domain could not be found in other non-metazoan organisms.
T1758 1004-1006 DT denotes No
T1759 1007-1017 NN denotes conclusion
T1761 1018-1023 MD denotes could
T1762 1024-1026 VB denotes be
T1760 1027-1031 VBN denotes made
T1763 1032-1037 IN denotes about
T1764 1038-1041 DT denotes the
T1765 1042-1051 NN denotes existence
T1766 1052-1054 IN denotes of
T1767 1055-1059 NN denotes TACC
T1769 1059-1060 HYPH denotes -
T1768 1060-1064 JJ denotes like
T1770 1065-1073 NN denotes sequence
T1771 1074-1076 IN denotes in
T1772 1077-1091 JJ denotes non-bilaterian
T1773 1092-1101 NNS denotes metazoans
T1774 1101-1103 , denotes ,
T1775 1103-1107 JJ denotes such
T1776 1108-1110 IN denotes as
T1777 1111-1119 NNP denotes Cnidaria
T1778 1120-1122 CC denotes or
T1779 1123-1131 NNP denotes Porifera
T1780 1131-1133 , denotes ,
T1781 1133-1136 IN denotes due
T1782 1137-1139 IN denotes to
T1783 1140-1143 DT denotes the
T1784 1144-1151 NN denotes paucity
T1785 1152-1154 IN denotes of
T1786 1155-1163 NN denotes sequence
T1787 1164-1175 NN denotes information
T1788 1176-1179 IN denotes for
T1789 1180-1185 DT denotes these
T1790 1186-1195 NNS denotes organisms
T1791 1195-1197 , denotes ,
T1792 1197-1200 CC denotes and
T1793 1201-1211 JJ denotes additional
T1795 1212-1222 JJ denotes definitive
T1794 1223-1232 NNS denotes sequences
T1797 1233-1237 IN denotes with
T1798 1238-1239 DT denotes a
T1800 1240-1247 VBN denotes defined
T1801 1248-1252 NN denotes TACC
T1799 1253-1259 NN denotes domain
T1802 1260-1265 MD denotes could
T1803 1266-1269 RB denotes not
T1804 1270-1272 VB denotes be
T1796 1273-1278 VBN denotes found
T1805 1279-1281 IN denotes in
T1806 1282-1287 JJ denotes other
T1808 1288-1300 JJ denotes non-metazoan
T1807 1301-1310 NNS denotes organisms
T1809 1310-1311 . denotes .
T1810 1311-1312 sentence denotes
T12469 1322-1334 JJ denotes Phylogenetic
T12470 1335-1343 NN denotes analysis
T12471 1344-1346 IN denotes of
T12472 1347-1350 DT denotes the
T12474 1351-1355 NN denotes TACC
T12475 1356-1362 NN denotes family
T12473 1363-1370 NNS denotes members
T12476 1371-1379 VBN denotes compared
T12477 1380-1382 IN denotes to
T12478 1383-1388 JJ denotes other
T12480 1389-1395 VBN denotes coiled
T12481 1396-1400 NN denotes coil
T12479 1401-1409 NN denotes proteins
T12482 1409-1410 . denotes .
T12483 1410-1485 sentence denotes The phylogenetic tree was constructed as described in the Methods section.
T12484 1411-1414 DT denotes The
T12486 1415-1427 JJ denotes phylogenetic
T12485 1428-1432 NN denotes tree
T12488 1433-1436 VBD denotes was
T12487 1437-1448 VBN denotes constructed
T12489 1449-1451 IN denotes as
T12490 1452-1461 VBN denotes described
T12491 1462-1464 IN denotes in
T12492 1465-1468 DT denotes the
T12494 1469-1476 NNS denotes Methods
T12493 1477-1484 NN denotes section
T12495 1484-1485 . denotes .
T12496 1485-1653 sentence denotes The TACC family defines a separate subfamily of coiled coil containing proteins, distinct from other coiled coil families such as the keratins, RHAMM and tropomyosins.
T12497 1486-1489 DT denotes The
T12499 1490-1494 NN denotes TACC
T12498 1495-1501 NN denotes family
T12500 1502-1509 VBZ denotes defines
T12501 1510-1511 DT denotes a
T12503 1512-1520 JJ denotes separate
T12502 1521-1530 NN denotes subfamily
T12504 1531-1533 IN denotes of
T12505 1534-1540 VBN denotes coiled
T12506 1541-1545 NN denotes coil
T12507 1546-1556 VBG denotes containing
T12508 1557-1565 NN denotes proteins
T12509 1565-1567 , denotes ,
T12510 1567-1575 JJ denotes distinct
T12511 1576-1580 IN denotes from
T12512 1581-1586 JJ denotes other
T12514 1587-1593 VBN denotes coiled
T12515 1594-1598 NN denotes coil
T12513 1599-1607 NNS denotes families
T12516 1608-1612 JJ denotes such
T12517 1613-1615 IN denotes as
T12518 1616-1619 DT denotes the
T12519 1620-1628 NNS denotes keratins
T12520 1628-1630 , denotes ,
T12521 1630-1635 NN denotes RHAMM
T12522 1636-1639 CC denotes and
T12523 1640-1652 NNS denotes tropomyosins
T12524 1652-1653 . denotes .
T12525 1653-1803 sentence denotes Note that the RHAMM proteins form a separate branch more closely related to the tropomyosins and kinesin like proteins (KLP), than the TACC proteins.
T12526 1654-1658 VB denotes Note
T12527 1659-1663 IN denotes that
T12529 1664-1667 DT denotes the
T12531 1668-1673 NN denotes RHAMM
T12530 1674-1682 NN denotes proteins
T12528 1683-1687 VBP denotes form
T12532 1688-1689 DT denotes a
T12534 1690-1698 JJ denotes separate
T12533 1699-1705 NN denotes branch
T12535 1706-1710 RBR denotes more
T12536 1711-1718 RB denotes closely
T12537 1719-1726 JJ denotes related
T12538 1727-1729 IN denotes to
T12539 1730-1733 DT denotes the
T12540 1734-1746 NNS denotes tropomyosins
T12541 1747-1750 CC denotes and
T12542 1751-1758 NN denotes kinesin
T12543 1759-1763 JJ denotes like
T12544 1764-1772 NN denotes proteins
T12545 1773-1774 -LRB- denotes (
T12546 1774-1777 NN denotes KLP
T12547 1777-1778 -RRB- denotes )
T12548 1778-1780 , denotes ,
T12549 1780-1784 IN denotes than
T12550 1785-1788 DT denotes the
T12552 1789-1793 NN denotes TACC
T12551 1794-1802 NN denotes proteins
T12553 1802-1803 . denotes .
T1812 1804-1805 NN denotes A
T1811 1804-1811 sentence denotes At the
T1813 1805-1806 IN denotes t
T1814 1807-1810 JJ denotes the
T1815 1811-1812 sentence denotes b
T1816 1811-1812 VBN denotes b
T1818 1812-1813 NN denotes a
T1817 1812-1826 sentence denotes ase of the cho
T1819 1813-1814 VBZ denotes s
T1820 1814-1815 JJ denotes e
T1821 1816-1818 IN denotes of
T1822 1819-1820 VBG denotes t
T1823 1820-1822 JJ denotes he
T1824 1823-1824 VBN denotes c
T1825 1824-1825 JJ denotes h
T1826 1825-1826 NNS denotes o
T1828 1826-1827 NN denotes r
T1827 1826-1832 sentence denotes rdate
T1829 1827-1828 JJ denotes d
T1830 1828-1829 CC denotes a
T1831 1829-1831 NN denotes te
T1834 1832-1833 NN denotes b
T1832 1832-2030 sentence denotes branch of life, a single TACC gene was identified in the genome of the urochordate Ciona intestinalis [11], and a partial TACC sequence from an analysis of the Halocynthia rortezi EST database [12].
T1836 1833-1835 NN denotes ra
T1835 1835-1838 NN denotes nch
T1837 1839-1841 IN denotes of
T1838 1842-1846 NN denotes life
T1839 1846-1848 , denotes ,
T1840 1848-1849 DT denotes a
T1842 1850-1856 JJ denotes single
T1843 1857-1861 NN denotes TACC
T1841 1862-1866 NN denotes gene
T1844 1867-1870 VBD denotes was
T1833 1871-1881 VBN denotes identified
T1845 1882-1884 IN denotes in
T1846 1885-1888 DT denotes the
T1847 1889-1895 NN denotes genome
T1848 1896-1898 IN denotes of
T1849 1899-1902 DT denotes the
T1850 1903-1914 NN denotes urochordate
T1851 1915-1920 NNP denotes Ciona
T1852 1921-1933 NNP denotes intestinalis
T1853 1934-1935 -LRB- denotes [
T1854 1935-1937 CD denotes 11
T1855 1937-1938 -RRB- denotes ]
T1856 1938-1940 , denotes ,
T1857 1940-1943 CC denotes and
T1858 1944-1945 DT denotes a
T1860 1946-1953 JJ denotes partial
T1861 1954-1958 NN denotes TACC
T1859 1959-1967 NN denotes sequence
T1862 1968-1972 IN denotes from
T1863 1973-1975 DT denotes an
T1864 1976-1984 NN denotes analysis
T1865 1985-1987 IN denotes of
T1866 1988-1991 DT denotes the
T1868 1992-2003 NNP denotes Halocynthia
T1869 2004-2011 NNP denotes rortezi
T1870 2012-2015 NN denotes EST
T1867 2016-2024 NN denotes database
T1871 2025-2026 -LRB- denotes [
T1872 2026-2028 CD denotes 12
T1873 2028-2029 -RRB- denotes ]
T1874 2029-2030 . denotes .
T1875 2030-2130 sentence denotes This confirms the original assumption that a single TACC gene was present in the chordate ancestor.
T1876 2031-2035 DT denotes This
T1877 2036-2044 VBZ denotes confirms
T1878 2045-2048 DT denotes the
T1880 2049-2057 JJ denotes original
T1879 2058-2068 NN denotes assumption
T1881 2069-2073 IN denotes that
T1883 2074-2075 DT denotes a
T1885 2076-2082 JJ denotes single
T1886 2083-2087 NN denotes TACC
T1884 2088-2092 NN denotes gene
T1882 2093-2096 VBD denotes was
T1887 2097-2104 JJ denotes present
T1888 2105-2107 IN denotes in
T1889 2108-2111 DT denotes the
T1891 2112-2120 NN denotes chordate
T1890 2121-2129 NN denotes ancestor
T1892 2129-2130 . denotes .
T1893 2130-2370 sentence denotes The next major event in the evolution of the chordate genome has been suggested to have occurred 687 ± 155.7 million years ago (MYA), with the first duplication of the chordate genome, and a second duplication occurring shortly thereafter.
T1894 2131-2134 DT denotes The
T1896 2135-2139 JJ denotes next
T1897 2140-2145 JJ denotes major
T1895 2146-2151 NN denotes event
T1899 2152-2154 IN denotes in
T1900 2155-2158 DT denotes the
T1901 2159-2168 NN denotes evolution
T1902 2169-2171 IN denotes of
T1903 2172-2175 DT denotes the
T1905 2176-2184 NN denotes chordate
T1904 2185-2191 NN denotes genome
T1906 2192-2195 VBZ denotes has
T1907 2196-2200 VBN denotes been
T1898 2201-2210 VBN denotes suggested
T1908 2211-2213 TO denotes to
T1910 2214-2218 VB denotes have
T1909 2219-2227 VBN denotes occurred
T1911 2228-2231 CD denotes 687
T1913 2232-2233 SYM denotes ±
T1912 2234-2239 CD denotes 155.7
T1915 2240-2247 CD denotes million
T1914 2248-2253 NNS denotes years
T1916 2254-2257 RB denotes ago
T1917 2258-2259 -LRB- denotes (
T1918 2259-2262 RB denotes MYA
T1919 2262-2263 -RRB- denotes )
T1920 2263-2265 , denotes ,
T1921 2265-2269 IN denotes with
T1922 2270-2273 DT denotes the
T1924 2274-2279 JJ denotes first
T1923 2280-2291 NN denotes duplication
T1925 2292-2294 IN denotes of
T1926 2295-2298 DT denotes the
T1928 2299-2307 NN denotes chordate
T1927 2308-2314 NN denotes genome
T1929 2314-2316 , denotes ,
T1930 2316-2319 CC denotes and
T1931 2320-2321 DT denotes a
T1933 2322-2328 JJ denotes second
T1932 2329-2340 NN denotes duplication
T1934 2341-2350 VBG denotes occurring
T1935 2351-2358 RB denotes shortly
T1936 2359-2369 RB denotes thereafter
T1937 2369-2370 . denotes .
T1938 2370-2809 sentence denotes Thus, if the TACC genes were duplicated at both events, we would expect to identify four TACC genes in the most "primitive" compact vertebrate genome sequenced to date, the pufferfish Takifugu rubripes, with three genes corresponding to the human TACC1-3, and, in keeping with the proposed model for genomic duplication of the chromosomal loci for the TACC genes (discussed below), a possible fourth gene deriving from the TACC3 ancestor.
T1939 2371-2375 RB denotes Thus
T1941 2375-2377 , denotes ,
T1942 2377-2379 IN denotes if
T1944 2380-2383 DT denotes the
T1946 2384-2388 NN denotes TACC
T1945 2389-2394 NNS denotes genes
T1947 2395-2399 VBD denotes were
T1943 2400-2410 VBN denotes duplicated
T1948 2411-2413 IN denotes at
T1949 2414-2418 DT denotes both
T1950 2419-2425 NNS denotes events
T1951 2425-2427 , denotes ,
T1952 2427-2429 PRP denotes we
T1953 2430-2435 MD denotes would
T1940 2436-2442 VB denotes expect
T1954 2443-2445 TO denotes to
T1955 2446-2454 VB denotes identify
T1956 2455-2459 CD denotes four
T1958 2460-2464 NN denotes TACC
T1957 2465-2470 NNS denotes genes
T1959 2471-2473 IN denotes in
T1960 2474-2477 DT denotes the
T1962 2478-2482 JJS denotes most
T1964 2483-2484 `` denotes "
T1963 2484-2493 JJ denotes primitive
T1965 2493-2494 '' denotes "
T1966 2495-2502 JJ denotes compact
T1967 2503-2513 NN denotes vertebrate
T1961 2514-2520 NN denotes genome
T1968 2521-2530 VBN denotes sequenced
T1969 2531-2533 IN denotes to
T1970 2534-2538 NN denotes date
T1971 2538-2540 , denotes ,
T1972 2540-2543 DT denotes the
T1973 2544-2554 NN denotes pufferfish
T1974 2555-2563 NNP denotes Takifugu
T1975 2564-2572 NNP denotes rubripes
T1976 2572-2574 , denotes ,
T1977 2574-2578 IN denotes with
T1978 2579-2584 CD denotes three
T1979 2585-2590 NNS denotes genes
T1980 2591-2604 VBG denotes corresponding
T1981 2605-2607 IN denotes to
T1982 2608-2611 DT denotes the
T1984 2612-2617 JJ denotes human
T1983 2618-2623 NN denotes TACC1
T1985 2623-2624 HYPH denotes -
T1986 2624-2625 CD denotes 3
T1987 2625-2627 , denotes ,
T1988 2627-2630 CC denotes and
T1989 2630-2632 , denotes ,
T1990 2632-2634 IN denotes in
T1992 2635-2642 VBG denotes keeping
T1993 2643-2647 IN denotes with
T1994 2648-2651 DT denotes the
T1996 2652-2660 VBN denotes proposed
T1995 2661-2666 NN denotes model
T1997 2667-2670 IN denotes for
T1998 2671-2678 JJ denotes genomic
T1999 2679-2690 NN denotes duplication
T2000 2691-2693 IN denotes of
T2001 2694-2697 DT denotes the
T2003 2698-2709 JJ denotes chromosomal
T2002 2710-2714 NNS denotes loci
T2004 2715-2718 IN denotes for
T2005 2719-2722 DT denotes the
T2007 2723-2727 NN denotes TACC
T2006 2728-2733 NNS denotes genes
T2008 2734-2735 -LRB- denotes (
T2009 2735-2744 VBN denotes discussed
T2010 2745-2750 RB denotes below
T2011 2750-2751 -RRB- denotes )
T2012 2751-2753 , denotes ,
T2013 2753-2754 DT denotes a
T2014 2755-2763 JJ denotes possible
T2015 2764-2770 JJ denotes fourth
T1991 2771-2775 NN denotes gene
T2016 2776-2784 VBG denotes deriving
T2017 2785-2789 IN denotes from
T2018 2790-2793 DT denotes the
T2020 2794-2799 NN denotes TACC3
T2019 2800-2808 NN denotes ancestor
T2021 2808-2809 . denotes .
T2022 2809-2865 sentence denotes Indeed, four TACC genes were identified in T. rubripes.
T2023 2810-2816 RB denotes Indeed
T2025 2816-2818 , denotes ,
T2026 2818-2822 CD denotes four
T2028 2823-2827 NN denotes TACC
T2027 2828-2833 NNS denotes genes
T2029 2834-2838 VBD denotes were
T2024 2839-2849 VBN denotes identified
T2030 2850-2852 IN denotes in
T2031 2853-2855 NNP denotes T.
T2032 2856-2864 NNP denotes rubripes
T2033 2864-2865 . denotes .
T2034 2865-2955 sentence denotes Of these, two genes corresponded to the T. rubripes orthologues of human TACC2 and TACC3.
T2035 2866-2868 IN denotes Of
T2037 2869-2874 DT denotes these
T2038 2874-2876 , denotes ,
T2039 2876-2879 CD denotes two
T2040 2880-2885 NNS denotes genes
T2036 2886-2898 VBD denotes corresponded
T2041 2899-2901 IN denotes to
T2042 2902-2905 DT denotes the
T2044 2906-2908 NNP denotes T.
T2045 2909-2917 NNP denotes rubripes
T2043 2918-2929 NNS denotes orthologues
T2046 2930-2932 IN denotes of
T2047 2933-2938 JJ denotes human
T2048 2939-2944 NN denotes TACC2
T2049 2945-2948 CC denotes and
T2050 2949-2954 NN denotes TACC3
T2051 2954-2955 . denotes .
T2052 2955-3051 sentence denotes However, the other two genes, trTACC1A and trTACC1B are clearly most related to TACC1 (Fig. 1).
T2053 2956-2963 RB denotes However
T2055 2963-2965 , denotes ,
T2056 2965-2968 DT denotes the
T2058 2969-2974 JJ denotes other
T2059 2975-2978 CD denotes two
T2057 2979-2984 NNS denotes genes
T2060 2984-2986 , denotes ,
T2061 2986-2994 NN denotes trTACC1A
T2062 2995-2998 CC denotes and
T2063 2999-3007 NN denotes trTACC1B
T2054 3008-3011 VBP denotes are
T2064 3012-3019 RB denotes clearly
T2065 3020-3024 RBS denotes most
T2066 3025-3032 JJ denotes related
T2067 3033-3035 IN denotes to
T2068 3036-3041 NN denotes TACC1
T2069 3042-3043 -LRB- denotes (
T2070 3043-3047 NN denotes Fig.
T2071 3048-3049 CD denotes 1
T2072 3049-3050 -RRB- denotes )
T2073 3050-3051 . denotes .
T2074 3051-3165 sentence denotes Although trTACC1A is highly homologous to trTACC1B, the latter encodes a significantly smaller predicted protein.
T2075 3052-3060 IN denotes Although
T2077 3061-3069 NN denotes trTACC1A
T2076 3070-3072 VBZ denotes is
T2079 3073-3079 RB denotes highly
T2080 3080-3090 JJ denotes homologous
T2081 3091-3093 IN denotes to
T2082 3094-3102 NN denotes trTACC1B
T2083 3102-3104 , denotes ,
T2084 3104-3107 DT denotes the
T2085 3108-3114 JJ denotes latter
T2078 3115-3122 VBZ denotes encodes
T2086 3123-3124 DT denotes a
T2088 3125-3138 RB denotes significantly
T2089 3139-3146 JJR denotes smaller
T2090 3147-3156 VBN denotes predicted
T2087 3157-3164 NN denotes protein
T2091 3164-3165 . denotes .
T2092 3165-3272 sentence denotes The trTACC1B gene is encoded by 15 exons over approximately 7 kb of the Takifugu Scaffold 191 (see below).
T2093 3166-3169 DT denotes The
T2095 3170-3178 NN denotes trTACC1B
T2094 3179-3183 NN denotes gene
T2097 3184-3186 VBZ denotes is
T2096 3187-3194 VBN denotes encoded
T2098 3195-3197 IN denotes by
T2099 3198-3200 CD denotes 15
T2100 3201-3206 NNS denotes exons
T2101 3207-3211 IN denotes over
T2102 3212-3225 RB denotes approximately
T2103 3226-3227 CD denotes 7
T2104 3228-3230 NN denotes kb
T2105 3231-3233 IN denotes of
T2106 3234-3237 DT denotes the
T2108 3238-3246 NNP denotes Takifugu
T2107 3247-3255 NNP denotes Scaffold
T2109 3256-3259 CD denotes 191
T2110 3260-3261 -LRB- denotes (
T2111 3261-3264 VB denotes see
T2112 3265-3270 RB denotes below
T2113 3270-3271 -RRB- denotes )
T2114 3271-3272 . denotes .
T2115 3272-3413 sentence denotes A search of this region using the trTACC1A sequence and gene prediction software has so far failed to identify additional exons of trTACC1B.
T2116 3273-3274 DT denotes A
T2117 3275-3281 NN denotes search
T2119 3282-3284 IN denotes of
T2120 3285-3289 DT denotes this
T2121 3290-3296 NN denotes region
T2122 3297-3302 VBG denotes using
T2123 3303-3306 DT denotes the
T2125 3307-3315 NN denotes trTACC1A
T2126 3316-3324 NN denotes sequence
T2127 3325-3328 CC denotes and
T2128 3329-3333 NN denotes gene
T2129 3334-3344 NN denotes prediction
T2124 3345-3353 NN denotes software
T2130 3354-3357 VBZ denotes has
T2131 3358-3360 RB denotes so
T2132 3361-3364 RB denotes far
T2118 3365-3371 VBN denotes failed
T2133 3372-3374 TO denotes to
T2134 3375-3383 VB denotes identify
T2135 3384-3394 JJ denotes additional
T2136 3395-3400 NNS denotes exons
T2137 3401-3403 IN denotes of
T2138 3404-3412 NN denotes trTACC1B
T2139 3412-3413 . denotes .
T2140 3413-3710 sentence denotes However, given the intron/exon structure of this apparently complete gene, it appears likely that trTACC1B is active in the pufferfish, and presumably fulfils either a temporal-spatial specific function within the organism, or a distinct function from the larger trTACC1A product within the cell.
T2141 3414-3421 RB denotes However
T2143 3421-3423 , denotes ,
T2144 3423-3428 VBN denotes given
T2145 3429-3432 DT denotes the
T2147 3433-3439 NN denotes intron
T2149 3439-3440 HYPH denotes /
T2148 3440-3444 NN denotes exon
T2146 3445-3454 NN denotes structure
T2150 3455-3457 IN denotes of
T2151 3458-3462 DT denotes this
T2153 3463-3473 RB denotes apparently
T2154 3474-3482 JJ denotes complete
T2152 3483-3487 NN denotes gene
T2155 3487-3489 , denotes ,
T2156 3489-3491 PRP denotes it
T2142 3492-3499 VBZ denotes appears
T2157 3500-3506 JJ denotes likely
T2158 3507-3511 IN denotes that
T2160 3512-3520 NN denotes trTACC1B
T2159 3521-3523 VBZ denotes is
T2161 3524-3530 JJ denotes active
T2162 3531-3533 IN denotes in
T2163 3534-3537 DT denotes the
T2164 3538-3548 NN denotes pufferfish
T2165 3548-3550 , denotes ,
T2166 3550-3553 CC denotes and
T2167 3554-3564 RB denotes presumably
T2168 3565-3572 VBZ denotes fulfils
T2169 3573-3579 CC denotes either
T2171 3580-3581 DT denotes a
T2172 3582-3590 JJ denotes temporal
T2174 3590-3591 HYPH denotes -
T2173 3591-3598 JJ denotes spatial
T2175 3599-3607 JJ denotes specific
T2170 3608-3616 NN denotes function
T2176 3617-3623 IN denotes within
T2177 3624-3627 DT denotes the
T2178 3628-3636 NN denotes organism
T2179 3636-3638 , denotes ,
T2180 3638-3640 CC denotes or
T2181 3641-3642 DT denotes a
T2183 3643-3651 JJ denotes distinct
T2182 3652-3660 NN denotes function
T2184 3661-3665 IN denotes from
T2185 3666-3669 DT denotes the
T2187 3670-3676 JJR denotes larger
T2188 3677-3685 NN denotes trTACC1A
T2186 3686-3693 NN denotes product
T2189 3694-3700 IN denotes within
T2190 3701-3704 DT denotes the
T2191 3705-3709 NN denotes cell
T2192 3709-3710 . denotes .
T2193 3710-4002 sentence denotes Thus, based upon the surrounding chromosomal loci (see below), the trTACC1A and trTACC1B genes appear to have arisen from the duplication of the chromosomal segment containing the teleost TACC1 ancestor, during the additional partial genomic duplication that occurred in the teleost lineage.
T2194 3711-3715 RB denotes Thus
T2196 3715-3717 , denotes ,
T2197 3717-3722 VBN denotes based
T2198 3723-3727 IN denotes upon
T2199 3728-3731 DT denotes the
T2201 3732-3743 VBG denotes surrounding
T2202 3744-3755 JJ denotes chromosomal
T2200 3756-3760 NNS denotes loci
T2203 3761-3762 -LRB- denotes (
T2204 3762-3765 VB denotes see
T2205 3766-3771 RB denotes below
T2206 3771-3772 -RRB- denotes )
T2207 3772-3774 , denotes ,
T2208 3774-3777 DT denotes the
T2210 3778-3786 NN denotes trTACC1A
T2211 3787-3790 CC denotes and
T2212 3791-3799 NN denotes trTACC1B
T2209 3800-3805 NNS denotes genes
T2195 3806-3812 VBP denotes appear
T2213 3813-3815 TO denotes to
T2215 3816-3820 VB denotes have
T2214 3821-3827 VBN denotes arisen
T2216 3828-3832 IN denotes from
T2217 3833-3836 DT denotes the
T2218 3837-3848 NN denotes duplication
T2219 3849-3851 IN denotes of
T2220 3852-3855 DT denotes the
T2222 3856-3867 JJ denotes chromosomal
T2221 3868-3875 NN denotes segment
T2223 3876-3886 VBG denotes containing
T2224 3887-3890 DT denotes the
T2226 3891-3898 NN denotes teleost
T2227 3899-3904 NN denotes TACC1
T2225 3905-3913 NN denotes ancestor
T2228 3913-3915 , denotes ,
T2229 3915-3921 IN denotes during
T2230 3922-3925 DT denotes the
T2232 3926-3936 JJ denotes additional
T2233 3937-3944 JJ denotes partial
T2234 3945-3952 JJ denotes genomic
T2231 3953-3964 NN denotes duplication
T2235 3965-3969 WDT denotes that
T2236 3970-3978 VBD denotes occurred
T2237 3979-3981 IN denotes in
T2238 3982-3985 DT denotes the
T2240 3986-3993 NN denotes teleost
T2239 3994-4001 NN denotes lineage
T2241 4001-4002 . denotes .
T2242 4002-4189 sentence denotes Therefore, this analysis of T. rubripes does not support the hypothesis that the region surrounding the TACC3 ancestor was included in the second round of vertebrate genomic duplication.
T2243 4003-4012 RB denotes Therefore
T2245 4012-4014 , denotes ,
T2246 4014-4018 DT denotes this
T2247 4019-4027 NN denotes analysis
T2248 4028-4030 IN denotes of
T2249 4031-4033 NNP denotes T.
T2250 4034-4042 NNP denotes rubripes
T2251 4043-4047 VBZ denotes does
T2252 4048-4051 RB denotes not
T2244 4052-4059 VB denotes support
T2253 4060-4063 DT denotes the
T2254 4064-4074 NN denotes hypothesis
T2255 4075-4079 IN denotes that
T2257 4080-4083 DT denotes the
T2258 4084-4090 NN denotes region
T2259 4091-4102 VBG denotes surrounding
T2260 4103-4106 DT denotes the
T2262 4107-4112 NN denotes TACC3
T2261 4113-4121 NN denotes ancestor
T2263 4122-4125 VBD denotes was
T2256 4126-4134 VBN denotes included
T2264 4135-4137 IN denotes in
T2265 4138-4141 DT denotes the
T2267 4142-4148 JJ denotes second
T2266 4149-4154 NN denotes round
T2268 4155-4157 IN denotes of
T2269 4158-4168 NN denotes vertebrate
T2271 4169-4176 JJ denotes genomic
T2270 4177-4188 NN denotes duplication
T2272 4188-4189 . denotes .
T2273 4189-4397 sentence denotes Examination of higher vertebrates led to the identification of splice variants of TACC1 and TACC2 in Mus musculus, and the assembly of the previously unidentified orthologues of TACC1-3 from Rattus norvegus.
T2274 4190-4201 NN denotes Examination
T2276 4202-4204 IN denotes of
T2277 4205-4211 JJR denotes higher
T2278 4212-4223 NNS denotes vertebrates
T2275 4224-4227 VBD denotes led
T2279 4228-4230 IN denotes to
T2280 4231-4234 DT denotes the
T2281 4235-4249 NN denotes identification
T2282 4250-4252 IN denotes of
T2283 4253-4259 NN denotes splice
T2284 4260-4268 NNS denotes variants
T2285 4269-4271 IN denotes of
T2286 4272-4277 NN denotes TACC1
T2287 4278-4281 CC denotes and
T2288 4282-4287 NN denotes TACC2
T2289 4288-4290 IN denotes in
T2290 4291-4294 NNP denotes Mus
T2291 4295-4303 NNP denotes musculus
T2292 4303-4305 , denotes ,
T2293 4305-4308 CC denotes and
T2294 4309-4312 DT denotes the
T2295 4313-4321 NN denotes assembly
T2296 4322-4324 IN denotes of
T2297 4325-4328 DT denotes the
T2299 4329-4339 RB denotes previously
T2300 4340-4352 JJ denotes unidentified
T2298 4353-4364 NNS denotes orthologues
T2301 4365-4367 IN denotes of
T2302 4368-4373 NN denotes TACC1
T2303 4373-4374 HYPH denotes -
T2304 4374-4375 CD denotes 3
T2305 4376-4380 IN denotes from
T2306 4381-4387 NN denotes Rattus
T2307 4388-4396 NN denotes norvegus
T2308 4396-4397 . denotes .
T2309 4397-4463 sentence denotes In addition, the TACC1X sequence was found on mouse chromosome X.
T2310 4398-4400 IN denotes In
T2312 4401-4409 NN denotes addition
T2313 4409-4411 , denotes ,
T2314 4411-4414 DT denotes the
T2316 4415-4421 NN denotes TACC1X
T2315 4422-4430 NN denotes sequence
T2317 4431-4434 VBD denotes was
T2311 4435-4440 VBN denotes found
T2318 4441-4443 IN denotes on
T2319 4444-4449 NN denotes mouse
T2321 4450-4460 NN denotes chromosome
T2320 4461-4462 NN denotes X
T2322 4462-4463 . denotes .
T2323 4463-4620 sentence denotes This gene is clearly related to the mouse TACC1, however, further examination revealed a mouse B1 repeat distributed over the length of the proposed intron.
T2324 4464-4468 DT denotes This
T2325 4469-4473 NN denotes gene
T2327 4474-4476 VBZ denotes is
T2328 4477-4484 RB denotes clearly
T2326 4485-4492 VBN denotes related
T2330 4493-4495 IN denotes to
T2331 4496-4499 DT denotes the
T2333 4500-4505 NN denotes mouse
T2332 4506-4511 NN denotes TACC1
T2334 4511-4513 , denotes ,
T2335 4513-4520 RB denotes however
T2336 4520-4522 , denotes ,
T2337 4522-4529 JJ denotes further
T2338 4530-4541 NN denotes examination
T2329 4542-4550 VBD denotes revealed
T2339 4551-4552 DT denotes a
T2341 4553-4558 NN denotes mouse
T2342 4559-4561 NN denotes B1
T2340 4562-4568 NN denotes repeat
T2343 4569-4580 VBN denotes distributed
T2344 4581-4585 IN denotes over
T2345 4586-4589 DT denotes the
T2346 4590-4596 NN denotes length
T2347 4597-4599 IN denotes of
T2348 4600-4603 DT denotes the
T2350 4604-4612 VBN denotes proposed
T2349 4613-4619 NN denotes intron
T2351 4619-4620 . denotes .
T2352 4620-4777 sentence denotes In addition, no expression of TACC1X was detected in mouse RNA by rt-PCR analysis (data not shown), suggesting that this sequence is a processed pseudogene.
T2353 4621-4623 IN denotes In
T2355 4624-4632 NN denotes addition
T2356 4632-4634 , denotes ,
T2357 4634-4636 DT denotes no
T2358 4637-4647 NN denotes expression
T2359 4648-4650 IN denotes of
T2360 4651-4657 NN denotes TACC1X
T2361 4658-4661 VBD denotes was
T2354 4662-4670 VBN denotes detected
T2362 4671-4673 IN denotes in
T2363 4674-4679 NN denotes mouse
T2364 4680-4683 NN denotes RNA
T2365 4684-4686 IN denotes by
T2366 4687-4689 NN denotes rt
T2368 4689-4690 HYPH denotes -
T2367 4690-4693 NN denotes PCR
T2369 4694-4702 NN denotes analysis
T2370 4703-4704 -LRB- denotes (
T2372 4704-4708 NNS denotes data
T2373 4709-4712 RB denotes not
T2371 4713-4718 VBN denotes shown
T2374 4718-4719 -RRB- denotes )
T2375 4719-4721 , denotes ,
T2376 4721-4731 VBG denotes suggesting
T2377 4732-4736 IN denotes that
T2379 4737-4741 DT denotes this
T2380 4742-4750 NN denotes sequence
T2378 4751-4753 VBZ denotes is
T2381 4754-4755 DT denotes a
T2383 4756-4765 VBN denotes processed
T2382 4766-4776 NN denotes pseudogene
T2384 4776-4777 . denotes .
T2385 4777-4986 sentence denotes Similarly, TACC1 pseudogenes also exist spread over 22 kb of the centromeric region of human chromosome 10 and, in 8q21, a shorter region 86% identical to the final 359 bp of the TACC1 3' untranslated region.
T2386 4778-4787 RB denotes Similarly
T2388 4787-4789 , denotes ,
T2389 4789-4794 NN denotes TACC1
T2390 4795-4806 NNS denotes pseudogenes
T2391 4807-4811 RB denotes also
T2387 4812-4817 VBP denotes exist
T2392 4818-4824 VBN denotes spread
T2393 4825-4829 IN denotes over
T2394 4830-4832 CD denotes 22
T2395 4833-4835 NN denotes kb
T2396 4836-4838 IN denotes of
T2397 4839-4842 DT denotes the
T2399 4843-4854 JJ denotes centromeric
T2398 4855-4861 NN denotes region
T2400 4862-4864 IN denotes of
T2401 4865-4870 JJ denotes human
T2402 4871-4881 NN denotes chromosome
T2403 4882-4884 CD denotes 10
T2404 4885-4888 CC denotes and
T2405 4888-4890 , denotes ,
T2406 4890-4892 IN denotes in
T2407 4893-4897 NN denotes 8q21
T2408 4897-4899 , denotes ,
T2409 4899-4900 DT denotes a
T2411 4901-4908 JJR denotes shorter
T2410 4909-4915 NN denotes region
T2412 4916-4918 CD denotes 86
T2413 4918-4919 NN denotes %
T2414 4920-4929 JJ denotes identical
T2415 4930-4932 IN denotes to
T2416 4933-4936 DT denotes the
T2418 4937-4942 JJ denotes final
T2419 4943-4946 CD denotes 359
T2417 4947-4949 NN denotes bp
T2420 4950-4952 IN denotes of
T2421 4953-4956 DT denotes the
T2423 4957-4962 NN denotes TACC1
T2424 4963-4964 CD denotes 3
T2425 4964-4965 SYM denotes '
T2426 4966-4978 JJ denotes untranslated
T2422 4979-4985 NN denotes region
T2427 4985-4986 . denotes .
T2428 4986-5075 sentence denotes No pseudogenes corresponding to TACC2 or TACC3 were identified in any mammalian species.
T2429 4987-4989 DT denotes No
T2430 4990-5001 NNS denotes pseudogenes
T2432 5002-5015 VBG denotes corresponding
T2433 5016-5018 IN denotes to
T2434 5019-5024 NN denotes TACC2
T2435 5025-5027 CC denotes or
T2436 5028-5033 NN denotes TACC3
T2437 5034-5038 VBD denotes were
T2431 5039-5049 VBN denotes identified
T2438 5050-5052 IN denotes in
T2439 5053-5056 DT denotes any
T2441 5057-5066 JJ denotes mammalian
T2440 5067-5074 NNS denotes species
T2442 5074-5075 . denotes .
R1000 T1795 T1794 amod definitive,sequences
R1001 T1796 T1760 conj found,made
R1002 T1797 T1794 prep with,sequences
R1003 T1798 T1799 det a,domain
R1004 T1799 T1797 pobj domain,with
R1005 T1800 T1799 amod defined,domain
R1006 T1801 T1799 compound TACC,domain
R1007 T1802 T1796 aux could,found
R1008 T1803 T1796 neg not,found
R1009 T1804 T1796 auxpass be,found
R1010 T1805 T1796 prep in,found
R1011 T1806 T1807 amod other,organisms
R1012 T1807 T1805 pobj organisms,in
R1013 T1808 T1807 amod non-metazoan,organisms
R1014 T1809 T1796 punct .,found
R1015 T1818 T1819 nsubj a,s
R1016 T1836 T1835 compound ra,nch
R1017 T1837 T1835 prep of,nch
R1018 T1838 T1837 pobj life,of
R1019 T1839 T1833 punct ", ",identified
R1020 T1840 T1841 det a,gene
R1021 T1841 T1833 nsubjpass gene,identified
R1022 T1842 T1841 amod single,gene
R1023 T1843 T1841 compound TACC,gene
R1024 T1844 T1833 auxpass was,identified
R1025 T1845 T1833 prep in,identified
R1026 T1846 T1847 det the,genome
R1027 T1847 T1845 pobj genome,in
R1028 T1848 T1847 prep of,genome
R1029 T1849 T1850 det the,urochordate
R1030 T1850 T1848 pobj urochordate,of
R1031 T1851 T1852 compound Ciona,intestinalis
R1032 T1852 T1850 appos intestinalis,urochordate
R1033 T1853 T1854 punct [,11
R1034 T1854 T1850 parataxis 11,urochordate
R1035 T1855 T1854 punct ],11
R1036 T1856 T1847 punct ", ",genome
R1037 T1857 T1847 cc and,genome
R1038 T1858 T1859 det a,sequence
R1039 T1859 T1847 conj sequence,genome
R1040 T1860 T1859 amod partial,sequence
R1041 T1861 T1859 compound TACC,sequence
R1042 T1862 T1859 prep from,sequence
R1043 T1863 T1864 det an,analysis
R1044 T1864 T1862 pobj analysis,from
R1045 T1865 T1864 prep of,analysis
R1046 T1866 T1867 det the,database
R1047 T1867 T1865 pobj database,of
R1048 T1868 T1869 compound Halocynthia,rortezi
R1049 T1869 T1867 compound rortezi,database
R1050 T1870 T1867 compound EST,database
R1051 T1871 T1872 punct [,12
R1052 T1872 T1864 parataxis 12,analysis
R1053 T1873 T1872 punct ],12
R1054 T1874 T1833 punct .,identified
R1055 T1876 T1877 nsubj This,confirms
R1056 T1878 T1879 det the,assumption
R1057 T1879 T1877 dobj assumption,confirms
R1058 T1880 T1879 amod original,assumption
R1059 T1881 T1882 mark that,was
R1060 T1882 T1879 acl was,assumption
R1061 T1883 T1884 det a,gene
R1062 T1884 T1882 nsubj gene,was
R1063 T1885 T1884 amod single,gene
R1064 T1886 T1884 compound TACC,gene
R1065 T1887 T1882 acomp present,was
R1066 T1888 T1882 prep in,was
R1067 T1889 T1890 det the,ancestor
R1068 T1890 T1888 pobj ancestor,in
R1069 T1891 T1890 compound chordate,ancestor
R1070 T1892 T1877 punct .,confirms
R1071 T1894 T1895 det The,event
R1072 T1895 T1898 nsubjpass event,suggested
R1073 T1896 T1895 amod next,event
R1074 T1897 T1895 amod major,event
R1075 T1899 T1895 prep in,event
R1076 T1900 T1901 det the,evolution
R1077 T1901 T1899 pobj evolution,in
R1078 T1902 T1901 prep of,evolution
R1079 T1903 T1904 det the,genome
R1080 T1904 T1902 pobj genome,of
R1081 T1905 T1904 compound chordate,genome
R1082 T1906 T1898 aux has,suggested
R1083 T1907 T1898 auxpass been,suggested
R1084 T1908 T1909 aux to,occurred
R1085 T1909 T1898 xcomp occurred,suggested
R1086 T1910 T1909 aux have,occurred
R1087 T1911 T1912 quantmod 687,155.7
R1088 T1912 T1914 nummod 155.7,years
R1089 T1913 T1912 punct ±,155.7
R1090 T1914 T1916 npadvmod years,ago
R1091 T1915 T1914 nummod million,years
R1092 T1916 T1909 advmod ago,occurred
R1093 T1917 T1918 punct (,MYA
R1094 T1918 T1916 parataxis MYA,ago
R1095 T1919 T1918 punct ),MYA
R1096 T1920 T1909 punct ", ",occurred
R1097 T1921 T1909 prep with,occurred
R1098 T1922 T1923 det the,duplication
R1099 T1923 T1921 pobj duplication,with
R1100 T1924 T1923 amod first,duplication
R1101 T1925 T1923 prep of,duplication
R1102 T1926 T1927 det the,genome
R1103 T1927 T1925 pobj genome,of
R1104 T1928 T1927 compound chordate,genome
R1105 T1929 T1923 punct ", ",duplication
R1106 T1930 T1923 cc and,duplication
R1107 T1931 T1932 det a,duplication
R1108 T1932 T1923 conj duplication,duplication
R1109 T1933 T1932 amod second,duplication
R1110 T1934 T1932 acl occurring,duplication
R1111 T1935 T1936 advmod shortly,thereafter
R1112 T1936 T1934 advmod thereafter,occurring
R1113 T1937 T1898 punct .,suggested
R1114 T1939 T1940 advmod Thus,expect
R1115 T1941 T1940 punct ", ",expect
R1116 T1942 T1943 mark if,duplicated
R1117 T1943 T1940 advcl duplicated,expect
R1118 T1944 T1945 det the,genes
R1119 T1945 T1943 nsubjpass genes,duplicated
R1120 T1946 T1945 compound TACC,genes
R1121 T1947 T1943 auxpass were,duplicated
R1122 T1948 T1943 prep at,duplicated
R1123 T1949 T1950 det both,events
R1124 T1950 T1948 pobj events,at
R1125 T1951 T1940 punct ", ",expect
R1126 T1952 T1940 nsubj we,expect
R1127 T1953 T1940 aux would,expect
R1128 T1954 T1955 aux to,identify
R1129 T1955 T1940 xcomp identify,expect
R1130 T1956 T1957 nummod four,genes
R1131 T1957 T1955 dobj genes,identify
R1132 T1958 T1957 compound TACC,genes
R1133 T1959 T1955 prep in,identify
R1134 T1960 T1961 det the,genome
R1135 T1961 T1959 pobj genome,in
R1136 T1962 T1963 amod most,primitive
R1137 T1963 T1961 amod primitive,genome
R1138 T1964 T1963 punct """",primitive
R1139 T1965 T1963 punct """",primitive
R1140 T1966 T1961 amod compact,genome
R1141 T1967 T1961 compound vertebrate,genome
R1142 T1968 T1961 acl sequenced,genome
R1143 T1969 T1961 prep to,genome
R1144 T1970 T1969 pobj date,to
R1145 T1971 T1961 punct ", ",genome
R1146 T1972 T1973 det the,pufferfish
R1147 T1973 T1961 appos pufferfish,genome
R1148 T1974 T1975 compound Takifugu,rubripes
R1149 T1975 T1973 appos rubripes,pufferfish
R1150 T1976 T1973 punct ", ",pufferfish
R1151 T1977 T1973 prep with,pufferfish
R1152 T1978 T1979 nummod three,genes
R1153 T1979 T1977 pobj genes,with
R1154 T1980 T1979 acl corresponding,genes
R1155 T1981 T1980 prep to,corresponding
R1156 T1982 T1983 det the,TACC1
R1157 T1983 T1981 pobj TACC1,to
R1158 T1984 T1983 amod human,TACC1
R1159 T1985 T1983 punct -,TACC1
R1160 T1986 T1983 nummod 3,TACC1
R1161 T1987 T1979 punct ", ",genes
R1162 T1988 T1979 cc and,genes
R1163 T1989 T1979 punct ", ",genes
R1164 T1990 T1991 prep in,gene
R1165 T1991 T1979 conj gene,genes
R1166 T1992 T1990 pobj keeping,in
R1167 T1993 T1992 prep with,keeping
R1168 T1994 T1995 det the,model
R1169 T1995 T1993 pobj model,with
R1170 T1996 T1995 amod proposed,model
R1171 T1997 T1995 prep for,model
R1172 T1998 T1999 amod genomic,duplication
R1173 T1999 T1997 pobj duplication,for
R1174 T2000 T1999 prep of,duplication
R1175 T2001 T2002 det the,loci
R1176 T2002 T2000 pobj loci,of
R1177 T2003 T2002 amod chromosomal,loci
R1178 T2004 T1995 prep for,model
R1179 T2005 T2006 det the,genes
R1180 T2006 T2004 pobj genes,for
R1181 T2007 T2006 compound TACC,genes
R1182 T2008 T2009 punct (,discussed
R1183 T2009 T1995 parataxis discussed,model
R1184 T2010 T2009 advmod below,discussed
R1185 T2011 T2009 punct ),discussed
R1186 T2012 T1991 punct ", ",gene
R1187 T2013 T1991 det a,gene
R1188 T2014 T1991 amod possible,gene
R1189 T2015 T1991 amod fourth,gene
R1190 T2016 T1991 acl deriving,gene
R1191 T2017 T2016 prep from,deriving
R1192 T2018 T2019 det the,ancestor
R1193 T2019 T2017 pobj ancestor,from
R1194 T2020 T2019 compound TACC3,ancestor
R1195 T2021 T1940 punct .,expect
R1196 T2023 T2024 advmod Indeed,identified
R1197 T2025 T2024 punct ", ",identified
R1198 T2026 T2027 nummod four,genes
R1199 T2027 T2024 nsubjpass genes,identified
R1200 T2028 T2027 compound TACC,genes
R1201 T2029 T2024 auxpass were,identified
R1202 T2030 T2024 prep in,identified
R1203 T2031 T2032 compound T.,rubripes
R1204 T2032 T2030 pobj rubripes,in
R1205 T2033 T2024 punct .,identified
R1206 T2035 T2036 prep Of,corresponded
R1207 T2037 T2035 pobj these,Of
R1208 T2038 T2036 punct ", ",corresponded
R1209 T2039 T2040 nummod two,genes
R1210 T2040 T2036 nsubj genes,corresponded
R1211 T2041 T2036 prep to,corresponded
R1212 T2042 T2043 det the,orthologues
R1213 T2043 T2041 pobj orthologues,to
R1214 T2044 T2045 compound T.,rubripes
R1215 T2045 T2043 compound rubripes,orthologues
R1216 T2046 T2043 prep of,orthologues
R1217 T2047 T2048 amod human,TACC2
R1218 T2048 T2046 pobj TACC2,of
R1219 T2049 T2048 cc and,TACC2
R1220 T2050 T2048 conj TACC3,TACC2
R1221 T2051 T2036 punct .,corresponded
R1222 T2053 T2054 advmod However,are
R1223 T2055 T2054 punct ", ",are
R1224 T2056 T2057 det the,genes
R1225 T2057 T2054 nsubj genes,are
R1226 T2058 T2057 amod other,genes
R1227 T2059 T2057 nummod two,genes
R1228 T2060 T2057 punct ", ",genes
R1229 T2061 T2057 appos trTACC1A,genes
R1230 T2062 T2061 cc and,trTACC1A
R1231 T2063 T2061 conj trTACC1B,trTACC1A
R1232 T2064 T2054 advmod clearly,are
R1233 T2065 T2066 advmod most,related
R1234 T2066 T2054 acomp related,are
R1235 T2067 T2066 prep to,related
R1236 T2068 T2067 pobj TACC1,to
R1237 T2069 T2070 punct (,Fig.
R1238 T2070 T2054 parataxis Fig.,are
R1239 T2071 T2070 nummod 1,Fig.
R1240 T2072 T2070 punct ),Fig.
R1241 T2073 T2054 punct .,are
R1242 T2075 T2076 mark Although,is
R1243 T2076 T2078 advcl is,encodes
R1244 T2077 T2076 nsubj trTACC1A,is
R1245 T2079 T2080 advmod highly,homologous
R1246 T2080 T2076 acomp homologous,is
R1247 T2081 T2080 prep to,homologous
R1248 T2082 T2081 pobj trTACC1B,to
R1249 T2083 T2078 punct ", ",encodes
R1250 T2084 T2085 det the,latter
R1251 T2085 T2078 nsubj latter,encodes
R1252 T2086 T2087 det a,protein
R1253 T2087 T2078 dobj protein,encodes
R1254 T2088 T2089 advmod significantly,smaller
R1255 T2089 T2087 amod smaller,protein
R1256 T2090 T2087 amod predicted,protein
R1257 T2091 T2078 punct .,encodes
R1258 T2093 T2094 det The,gene
R1259 T2094 T2096 nsubjpass gene,encoded
R1260 T2095 T2094 compound trTACC1B,gene
R1261 T2097 T2096 auxpass is,encoded
R1262 T2098 T2096 agent by,encoded
R1263 T2099 T2100 nummod 15,exons
R1264 T2100 T2098 pobj exons,by
R1265 T2101 T2096 prep over,encoded
R1266 T2102 T2103 advmod approximately,7
R1267 T2103 T2104 nummod 7,kb
R1268 T2104 T2101 pobj kb,over
R1269 T2105 T2104 prep of,kb
R1270 T2106 T2107 det the,Scaffold
R1271 T2107 T2105 pobj Scaffold,of
R1272 T2108 T2107 compound Takifugu,Scaffold
R1273 T2109 T2107 nummod 191,Scaffold
R1274 T2110 T2111 punct (,see
R1275 T2111 T2096 parataxis see,encoded
R1276 T2112 T2111 advmod below,see
R1277 T2113 T2111 punct ),see
R1278 T2114 T2096 punct .,encoded
R1279 T2116 T2117 det A,search
R1280 T2117 T2118 nsubj search,failed
R1281 T2119 T2117 prep of,search
R1282 T2120 T2121 det this,region
R1283 T2121 T2119 pobj region,of
R1284 T2122 T2117 acl using,search
R1285 T2123 T2124 det the,software
R1286 T2124 T2122 dobj software,using
R1287 T2125 T2126 nmod trTACC1A,sequence
R1288 T2126 T2124 nmod sequence,software
R1289 T2127 T2126 cc and,sequence
R1290 T2128 T2129 compound gene,prediction
R1291 T2129 T2126 conj prediction,sequence
R1292 T2130 T2118 aux has,failed
R1293 T2131 T2132 advmod so,far
R1294 T2132 T2118 advmod far,failed
R1295 T2133 T2134 aux to,identify
R1296 T2134 T2118 xcomp identify,failed
R1297 T2135 T2136 amod additional,exons
R1298 T2136 T2134 dobj exons,identify
R1299 T2137 T2136 prep of,exons
R1300 T2138 T2137 pobj trTACC1B,of
R1301 T2139 T2118 punct .,failed
R1302 T2141 T2142 advmod However,appears
R1303 T2143 T2142 punct ", ",appears
R1304 T2144 T2142 prep given,appears
R1305 T2145 T2146 det the,structure
R1306 T2146 T2144 pobj structure,given
R1307 T2147 T2148 compound intron,exon
R1308 T2148 T2146 compound exon,structure
R1309 T2149 T2148 punct /,exon
R1310 T2150 T2146 prep of,structure
R1311 T2151 T2152 det this,gene
R1312 T2152 T2150 pobj gene,of
R1313 T2153 T2154 advmod apparently,complete
R1314 T2154 T2152 amod complete,gene
R1315 T2155 T2142 punct ", ",appears
R1316 T2156 T2142 nsubj it,appears
R1317 T2157 T2142 oprd likely,appears
R1318 T2158 T2159 mark that,is
R1319 T2159 T2142 ccomp is,appears
R1320 T2160 T2159 nsubj trTACC1B,is
R1321 T2161 T2159 acomp active,is
R1322 T2162 T2159 prep in,is
R1323 T2163 T2164 det the,pufferfish
R1324 T2164 T2162 pobj pufferfish,in
R1325 T2165 T2159 punct ", ",is
R1326 T2166 T2159 cc and,is
R1327 T2167 T2168 advmod presumably,fulfils
R1328 T2168 T2159 conj fulfils,is
R1329 T2169 T2170 preconj either,function
R1330 T2170 T2168 dobj function,fulfils
R1331 T2171 T2170 det a,function
R1332 T2172 T2173 amod temporal,spatial
R1333 T2173 T2170 amod spatial,function
R1334 T2174 T2173 punct -,spatial
R1335 T2175 T2170 amod specific,function
R1336 T2176 T2170 prep within,function
R1337 T2177 T2178 det the,organism
R1338 T2178 T2176 pobj organism,within
R1339 T2179 T2170 punct ", ",function
R1340 T2180 T2170 cc or,function
R1341 T2181 T2182 det a,function
R1342 T2182 T2170 conj function,function
R1343 T2183 T2182 amod distinct,function
R1344 T2184 T2182 prep from,function
R1345 T2185 T2186 det the,product
R1346 T2186 T2184 pobj product,from
R1347 T2187 T2186 amod larger,product
R1348 T2188 T2186 compound trTACC1A,product
R1349 T2189 T2182 prep within,function
R1350 T2190 T2191 det the,cell
R1351 T2191 T2189 pobj cell,within
R1352 T2192 T2142 punct .,appears
R1353 T2194 T2195 advmod Thus,appear
R1354 T2196 T2195 punct ", ",appear
R1355 T2197 T2195 prep based,appear
R1356 T2198 T2197 prep upon,based
R1357 T2199 T2200 det the,loci
R1358 T2200 T2198 pobj loci,upon
R1359 T2201 T2200 amod surrounding,loci
R1360 T2202 T2200 amod chromosomal,loci
R1361 T2203 T2204 punct (,see
R1362 T2204 T2200 parataxis see,loci
R1363 T2205 T2204 advmod below,see
R1364 T2206 T2204 punct ),see
R1365 T2207 T2195 punct ", ",appear
R1366 T2208 T2209 det the,genes
R1367 T2209 T2195 nsubj genes,appear
R1368 T2210 T2209 nmod trTACC1A,genes
R1369 T2211 T2210 cc and,trTACC1A
R1370 T2212 T2210 conj trTACC1B,trTACC1A
R1371 T2213 T2214 aux to,arisen
R1372 T2214 T2195 xcomp arisen,appear
R1373 T2215 T2214 aux have,arisen
R1374 T2216 T2214 prep from,arisen
R1375 T2217 T2218 det the,duplication
R1376 T2218 T2216 pobj duplication,from
R1377 T2219 T2218 prep of,duplication
R1378 T2220 T2221 det the,segment
R1379 T2221 T2219 pobj segment,of
R1380 T2222 T2221 amod chromosomal,segment
R1381 T2223 T2221 acl containing,segment
R1382 T2224 T2225 det the,ancestor
R1383 T2225 T2223 dobj ancestor,containing
R1384 T2226 T2225 compound teleost,ancestor
R1385 T2227 T2225 compound TACC1,ancestor
R1386 T2228 T2218 punct ", ",duplication
R1387 T2229 T2218 prep during,duplication
R1388 T2230 T2231 det the,duplication
R1389 T2231 T2229 pobj duplication,during
R1390 T2232 T2231 amod additional,duplication
R1391 T2233 T2231 amod partial,duplication
R1392 T2234 T2231 amod genomic,duplication
R1393 T2235 T2236 dep that,occurred
R1394 T2236 T2231 relcl occurred,duplication
R1395 T2237 T2236 prep in,occurred
R1396 T2238 T2239 det the,lineage
R1397 T2239 T2237 pobj lineage,in
R1398 T2240 T2239 compound teleost,lineage
R1399 T2241 T2195 punct .,appear
R1400 T2243 T2244 advmod Therefore,support
R1401 T2245 T2244 punct ", ",support
R1402 T2246 T2247 det this,analysis
R1403 T2247 T2244 nsubj analysis,support
R1404 T2248 T2247 prep of,analysis
R1405 T2249 T2250 compound T.,rubripes
R1406 T2250 T2248 pobj rubripes,of
R1407 T2251 T2244 aux does,support
R1408 T2252 T2244 neg not,support
R1409 T2253 T2254 det the,hypothesis
R1410 T2254 T2244 dobj hypothesis,support
R1411 T2255 T2256 mark that,included
R1412 T2256 T2254 acl included,hypothesis
R1413 T2257 T2258 det the,region
R1414 T2258 T2256 nsubjpass region,included
R1415 T2259 T2258 acl surrounding,region
R1416 T2260 T2261 det the,ancestor
R1417 T2261 T2259 dobj ancestor,surrounding
R1418 T2262 T2261 compound TACC3,ancestor
R1419 T2263 T2256 auxpass was,included
R1420 T2264 T2256 prep in,included
R1421 T2265 T2266 det the,round
R1422 T2266 T2264 pobj round,in
R1423 T2267 T2266 amod second,round
R1424 T2268 T2266 prep of,round
R1425 T2269 T2270 nmod vertebrate,duplication
R1426 T2270 T2268 pobj duplication,of
R1427 T2271 T2270 amod genomic,duplication
R1428 T2272 T2244 punct .,support
R1429 T2274 T2275 nsubj Examination,led
R1430 T2276 T2274 prep of,Examination
R1431 T2277 T2278 amod higher,vertebrates
R1432 T2278 T2276 pobj vertebrates,of
R1433 T2279 T2275 prep to,led
R1434 T2280 T2281 det the,identification
R1435 T2281 T2279 pobj identification,to
R1436 T2282 T2281 prep of,identification
R1437 T2283 T2284 compound splice,variants
R1438 T2284 T2282 pobj variants,of
R1439 T2285 T2284 prep of,variants
R1440 T2286 T2285 pobj TACC1,of
R1441 T2287 T2286 cc and,TACC1
R1442 T2288 T2286 conj TACC2,TACC1
R1443 T2289 T2281 prep in,identification
R1444 T2290 T2291 compound Mus,musculus
R1445 T2291 T2289 pobj musculus,in
R1446 T2292 T2281 punct ", ",identification
R1447 T2293 T2281 cc and,identification
R1448 T2294 T2295 det the,assembly
R1449 T2295 T2281 conj assembly,identification
R1450 T2296 T2295 prep of,assembly
R1451 T2297 T2298 det the,orthologues
R1452 T2298 T2296 pobj orthologues,of
R1453 T2299 T2300 advmod previously,unidentified
R1454 T2300 T2298 amod unidentified,orthologues
R1455 T2301 T2298 prep of,orthologues
R1456 T2302 T2301 pobj TACC1,of
R1457 T2303 T2302 punct -,TACC1
R1458 T2304 T2302 nummod 3,TACC1
R1459 T2305 T2295 prep from,assembly
R1460 T2306 T2307 compound Rattus,norvegus
R1461 T2307 T2305 pobj norvegus,from
R1462 T2308 T2275 punct .,led
R1463 T2310 T2311 prep In,found
R1464 T2312 T2310 pobj addition,In
R1465 T2313 T2311 punct ", ",found
R1466 T2314 T2315 det the,sequence
R1467 T2315 T2311 nsubjpass sequence,found
R1468 T2316 T2315 compound TACC1X,sequence
R1469 T2317 T2311 auxpass was,found
R1470 T2318 T2311 prep on,found
R1471 T2319 T2320 compound mouse,X
R1472 T2320 T2318 pobj X,on
R1473 T2321 T2320 compound chromosome,X
R1474 T2322 T2311 punct .,found
R1475 T2324 T2325 det This,gene
R1476 T2325 T2326 nsubjpass gene,related
R1477 T2326 T2329 ccomp related,revealed
R1478 T2327 T2326 auxpass is,related
R1479 T2328 T2326 advmod clearly,related
R1480 T2330 T2326 prep to,related
R1481 T2331 T2332 det the,TACC1
R1482 T2332 T2330 pobj TACC1,to
R1483 T2333 T2332 compound mouse,TACC1
R1484 T2334 T2329 punct ", ",revealed
R1485 T2335 T2329 advmod however,revealed
R1486 T2336 T2329 punct ", ",revealed
R1487 T2337 T2338 amod further,examination
R1488 T2338 T2329 nsubj examination,revealed
R1489 T2339 T2340 det a,repeat
R1490 T2340 T2329 dobj repeat,revealed
R1491 T2341 T2340 compound mouse,repeat
R1492 T2342 T2340 compound B1,repeat
R1493 T2343 T2340 acl distributed,repeat
R1494 T2344 T2343 prep over,distributed
R1495 T2345 T2346 det the,length
R1496 T2346 T2344 pobj length,over
R1497 T2347 T2346 prep of,length
R1498 T2348 T2349 det the,intron
R1499 T2349 T2347 pobj intron,of
R1500 T2350 T2349 amod proposed,intron
R1501 T2351 T2329 punct .,revealed
R1502 T2353 T2354 prep In,detected
R1503 T2355 T2353 pobj addition,In
R1504 T2356 T2354 punct ", ",detected
R1505 T2357 T2358 det no,expression
R1506 T2358 T2354 nsubjpass expression,detected
R1507 T2359 T2358 prep of,expression
R1508 T2360 T2359 pobj TACC1X,of
R1509 T2361 T2354 auxpass was,detected
R1510 T2362 T2354 prep in,detected
R1511 T2363 T2364 compound mouse,RNA
R1512 T2364 T2362 pobj RNA,in
R1513 T2365 T2354 prep by,detected
R1514 T2366 T2367 compound rt,PCR
R1515 T2367 T2369 compound PCR,analysis
R1516 T2368 T2367 punct -,PCR
R1517 T2369 T2365 pobj analysis,by
R1518 T2370 T2371 punct (,shown
R1519 T2371 T2354 parataxis shown,detected
R1520 T2372 T2371 nsubj data,shown
R1521 T2373 T2371 neg not,shown
R1522 T2374 T2371 punct ),shown
R1523 T2375 T2354 punct ", ",detected
R1524 T2376 T2354 advcl suggesting,detected
R1525 T2377 T2378 mark that,is
R1526 T2378 T2376 ccomp is,suggesting
R1527 T2379 T2380 det this,sequence
R1528 T2380 T2378 nsubj sequence,is
R1529 T2381 T2382 det a,pseudogene
R1530 T2382 T2378 attr pseudogene,is
R1531 T2383 T2382 amod processed,pseudogene
R1532 T2384 T2354 punct .,detected
R1533 T2386 T2387 advmod Similarly,exist
R1534 T2388 T2387 punct ", ",exist
R1535 T2389 T2390 compound TACC1,pseudogenes
R1536 T2390 T2387 nsubj pseudogenes,exist
R1537 T2391 T2387 advmod also,exist
R1538 T2392 T2387 advcl spread,exist
R1539 T2393 T2392 prep over,spread
R1540 T2394 T2395 nummod 22,kb
R1541 T2395 T2393 pobj kb,over
R1542 T2396 T2395 prep of,kb
R1543 T2397 T2398 det the,region
R1544 T2398 T2396 pobj region,of
R1545 T2399 T2398 amod centromeric,region
R1546 T2400 T2398 prep of,region
R1547 T2401 T2402 amod human,chromosome
R1548 T2402 T2400 pobj chromosome,of
R1549 T2403 T2402 nummod 10,chromosome
R1550 T2404 T2393 cc and,over
R1551 T2405 T2393 punct ", ",over
R1552 T2406 T2393 conj in,over
R1553 T2407 T2406 pobj 8q21,in
R1554 T2408 T2407 punct ", ",8q21
R1555 T2409 T2410 det a,region
R1556 T2410 T2407 appos region,8q21
R1557 T2411 T2410 amod shorter,region
R1558 T2412 T2413 nummod 86,%
R1559 T2413 T2414 npadvmod %,identical
R1560 T2414 T2410 amod identical,region
R1561 T2415 T2414 prep to,identical
R1562 T2416 T2417 det the,bp
R1563 T2417 T2415 pobj bp,to
R1564 T2418 T2417 amod final,bp
R1565 T2419 T2417 nummod 359,bp
R1566 T2420 T2417 prep of,bp
R1567 T2421 T2422 det the,region
R1568 T2422 T2420 pobj region,of
R1569 T2423 T2422 nmod TACC1,region
R1570 T2424 T2422 nummod 3,region
R1571 T2425 T2424 punct ',3
R1572 T2426 T2422 amod untranslated,region
R1573 T2427 T2387 punct .,exist
R1574 T2429 T2430 det No,pseudogenes
R1575 T2430 T2431 nsubjpass pseudogenes,identified
R1576 T2432 T2430 acl corresponding,pseudogenes
R1577 T2433 T2432 prep to,corresponding
R1578 T2434 T2433 pobj TACC2,to
R1579 T2435 T2434 cc or,TACC2
R1580 T2436 T2434 conj TACC3,TACC2
R1581 T2437 T2431 auxpass were,identified
R1582 T2438 T2431 prep in,identified
R1583 T2439 T2440 det any,species
R1584 T2440 T2438 pobj species,in
R1585 T2441 T2440 amod mammalian,species
R1586 T2442 T2431 punct .,identified
R8078 T12469 T12470 amod Phylogenetic,analysis
R8079 T12471 T12470 prep of,analysis
R8080 T12472 T12473 det the,members
R8081 T12473 T12471 pobj members,of
R8082 T12474 T12473 compound TACC,members
R8083 T12475 T12473 compound family,members
R8084 T12476 T12470 prep compared,analysis
R8085 T12477 T12476 prep to,compared
R8086 T12478 T12479 amod other,proteins
R8087 T12479 T12477 pobj proteins,to
R8088 T12480 T12481 amod coiled,coil
R8089 T12481 T12479 compound coil,proteins
R8090 T12482 T12470 punct .,analysis
R8091 T12484 T12485 det The,tree
R8092 T12485 T12487 nsubjpass tree,constructed
R8093 T12486 T12485 amod phylogenetic,tree
R8094 T12488 T12487 auxpass was,constructed
R8095 T12489 T12490 mark as,described
R8096 T12490 T12487 advcl described,constructed
R8097 T12491 T12490 prep in,described
R8098 T12492 T12493 det the,section
R8099 T12493 T12491 pobj section,in
R8100 T12494 T12493 compound Methods,section
R8101 T12495 T12487 punct .,constructed
R8102 T12497 T12498 det The,family
R8103 T12498 T12500 nsubj family,defines
R8104 T12499 T12498 compound TACC,family
R8105 T12501 T12502 det a,subfamily
R8106 T12502 T12500 dobj subfamily,defines
R8107 T12503 T12502 amod separate,subfamily
R8108 T12504 T12502 prep of,subfamily
R8109 T12505 T12506 amod coiled,coil
R811 T1593 T1594 advmod In,silico
R8110 T12506 T12507 npadvmod coil,containing
R8111 T12507 T12508 amod containing,proteins
R8112 T12508 T12504 pobj proteins,of
R8113 T12509 T12502 punct ", ",subfamily
R8114 T12510 T12502 amod distinct,subfamily
R8115 T12511 T12510 prep from,distinct
R8116 T12512 T12513 amod other,families
R8117 T12513 T12511 pobj families,from
R8118 T12514 T12515 amod coiled,coil
R8119 T12515 T12513 compound coil,families
R812 T1594 T1595 amod silico,identification
R8120 T12516 T12517 amod such,as
R8121 T12517 T12513 prep as,families
R8122 T12518 T12519 det the,keratins
R8123 T12519 T12517 pobj keratins,as
R8124 T12520 T12519 punct ", ",keratins
R8125 T12521 T12519 conj RHAMM,keratins
R8126 T12522 T12521 cc and,RHAMM
R8127 T12523 T12521 conj tropomyosins,RHAMM
R8128 T12524 T12500 punct .,defines
R8129 T12527 T12528 mark that,form
R813 T1596 T1595 prep of,identification
R8130 T12528 T12526 ccomp form,Note
R8131 T12529 T12530 det the,proteins
R8132 T12530 T12528 nsubj proteins,form
R8133 T12531 T12530 compound RHAMM,proteins
R8134 T12532 T12533 det a,branch
R8135 T12533 T12528 dobj branch,form
R8136 T12534 T12533 amod separate,branch
R8137 T12535 T12536 advmod more,closely
R8138 T12536 T12537 advmod closely,related
R8139 T12537 T12533 amod related,branch
R814 T1597 T1598 compound TACC,members
R8140 T12538 T12537 prep to,related
R8141 T12539 T12540 det the,tropomyosins
R8142 T12540 T12538 pobj tropomyosins,to
R8143 T12541 T12540 cc and,tropomyosins
R8144 T12542 T12543 npadvmod kinesin,like
R8145 T12543 T12544 amod like,proteins
R8146 T12544 T12540 conj proteins,tropomyosins
R8147 T12545 T12544 punct (,proteins
R8148 T12546 T12544 appos KLP,proteins
R8149 T12547 T12537 punct ),related
R815 T1598 T1596 pobj members,of
R8150 T12548 T12537 punct ", ",related
R8151 T12549 T12537 prep than,related
R8152 T12550 T12551 det the,proteins
R8153 T12551 T12549 pobj proteins,than
R8154 T12552 T12551 compound TACC,proteins
R8155 T12553 T12526 punct .,Note
R816 T1599 T1598 compound family,members
R817 T1600 T1598 prep from,members
R818 T1601 T1602 nmod vertebrate,lineages
R819 T1602 T1600 pobj lineages,from
R820 T1603 T1601 cc and,vertebrate
R821 T1604 T1601 conj invertebrate,vertebrate
R822 T1606 T1607 compound Sequence,similarity
R823 T1607 T1608 compound similarity,searches
R824 T1608 T1609 nsubjpass searches,performed
R825 T1610 T1608 prep of,searches
R826 T1611 T1612 det the,databases
R827 T1612 T1610 pobj databases,of
R828 T1613 T1614 advmod publicly,available
R829 T1614 T1612 amod available,databases
R830 T1615 T1612 compound genome,databases
R831 T1616 T1612 prep with,databases
R832 T1617 T1618 det the,programs
R833 T1618 T1616 pobj programs,with
R834 T1619 T1618 nmod BLAST,programs
R835 T1620 T1619 cc and,BLAST
R836 T1621 T1619 conj TBLAST,BLAST
R837 T1622 T1609 auxpass were,performed
R838 T1623 T1624 aux to,identify
R839 T1624 T1609 advcl identify,performed
R840 T1625 T1626 nmod TACC,orthologues
R841 T1626 T1624 dobj orthologues,identify
R842 T1627 T1625 cc and,TACC
R843 T1628 T1625 conj RHAMM,TACC
R844 T1629 T1626 punct ", ",orthologues
R845 T1630 T1626 cc and,orthologues
R846 T1631 T1632 amod other,members
R847 T1632 T1626 conj members,orthologues
R848 T1633 T1632 prep of,members
R849 T1634 T1635 det the,superfamily
R850 T1635 T1633 pobj superfamily,of
R851 T1636 T1637 amod coiled,coil
R852 T1637 T1635 compound coil,superfamily
R853 T1638 T1624 prep in,identify
R854 T1639 T1640 det a,set
R855 T1640 T1638 pobj set,in
R856 T1641 T1640 amod diverse,set
R857 T1642 T1640 prep of,set
R858 T1643 T1642 pobj species,of
R859 T1644 T1645 punct (,Fig.
R860 T1645 T1624 parataxis Fig.,identify
R861 T1646 T1645 nummod 1,Fig.
R862 T1647 T1645 punct ),Fig.
R863 T1648 T1609 punct .,performed
R864 T1650 T1651 nsubj This,identified
R865 T1652 T1653 det the,sequence
R866 T1653 T1651 dobj sequence,identified
R867 T1654 T1653 amod complete,sequence
R868 T1655 T1653 prep of,sequence
R869 T1656 T1657 det the,genes
R870 T1657 T1655 pobj genes,of
R871 T1658 T1657 compound TACC,genes
R872 T1659 T1651 prep in,identified
R873 T1660 T1659 pobj representatives,in
R874 T1661 T1660 prep of,representatives
R875 T1662 T1663 nummod five,clades
R876 T1663 T1661 pobj clades,of
R877 T1664 T1663 amod major,clades
R878 T1665 T1666 advmod phylogenetically,distinct
R879 T1666 T1663 amod distinct,clades
R880 T1667 T1651 punct .,identified
R881 T1669 T1670 advmod Where,possible
R882 T1670 T1671 advcl possible,confirmed
R883 T1672 T1671 punct ", ",confirmed
R884 T1673 T1674 det the,construction
R885 T1674 T1671 nsubjpass construction,confirmed
R886 T1675 T1674 prep of,construction
R887 T1676 T1677 det the,sequences
R888 T1677 T1675 pobj sequences,of
R889 T1678 T1677 compound TACC,sequences
R890 T1679 T1677 prep from,sequences
R891 T1680 T1681 det these,organisms
R892 T1681 T1679 pobj organisms,from
R893 T1682 T1671 auxpass was,confirmed
R894 T1683 T1671 advmod also,confirmed
R895 T1684 T1671 agent by,confirmed
R896 T1685 T1686 det the,analysis
R897 T1686 T1684 pobj analysis,by
R898 T1687 T1686 prep of,analysis
R899 T1688 T1689 det the,databases
R900 T1689 T1687 pobj databases,of
R901 T1690 T1689 compound cDNA,databases
R902 T1691 T1671 punct .,confirmed
R903 T1693 T1694 amod Several,sequences
R904 T1694 T1696 nsubjpass sequences,identified
R905 T1695 T1694 amod partial,sequences
R906 T1697 T1694 prep in,sequences
R907 T1698 T1699 amod other,species
R908 T1699 T1697 pobj species,in
R909 T1700 T1699 compound vertebrate,species
R910 T1701 T1699 punct ", ",species
R911 T1702 T1703 det the,echinodermate
R912 T1703 T1699 appos echinodermate,species
R913 T1704 T1705 compound Strongylocentrotus,purpuratus
R914 T1705 T1703 appos purpuratus,echinodermate
R915 T1706 T1703 cc and,echinodermate
R916 T1707 T1708 det the,insect
R917 T1708 T1703 conj insect,echinodermate
R918 T1709 T1708 compound protostome,insect
R919 T1710 T1711 compound Anopheles,gambiae
R920 T1711 T1708 appos gambiae,insect
R921 T1712 T1696 auxpass were,identified
R922 T1713 T1696 advmod also,identified
R923 T1714 T1696 punct ", ",identified
R924 T1715 T1696 advcl suggesting,identified
R925 T1716 T1717 det an,conservation
R926 T1717 T1715 dobj conservation,suggesting
R927 T1718 T1717 amod ancient,conservation
R928 T1719 T1717 prep of,conservation
R929 T1720 T1721 det the,genes
R930 T1721 T1719 pobj genes,of
R931 T1722 T1721 compound TACC,genes
R932 T1723 T1717 prep in,conservation
R933 T1724 T1725 compound metazoan,lineages
R934 T1725 T1723 pobj lineages,in
R935 T1726 T1696 punct .,identified
R936 T1728 T1729 advmod However,undertaken
R937 T1730 T1729 punct ", ",undertaken
R938 T1731 T1729 prep due,undertaken
R939 T1732 T1731 pcomp to,due
R940 T1733 T1734 det the,infancy
R941 T1734 T1731 pobj infancy,due
R942 T1735 T1734 amod relative,infancy
R943 T1736 T1734 prep of,infancy
R944 T1737 T1738 det the,projects
R945 T1738 T1736 pobj projects,of
R946 T1739 T1740 compound cDNA,genome
R947 T1740 T1738 compound genome,projects
R948 T1741 T1740 punct /,genome
R949 T1742 T1738 prep for,projects
R950 T1743 T1744 det these,organisms
R951 T1744 T1742 pobj organisms,for
R952 T1745 T1744 amod latter,organisms
R953 T1746 T1729 punct ", ",undertaken
R954 T1747 T1748 amod complete,characterization
R955 T1748 T1729 nsubjpass characterization,undertaken
R956 T1749 T1748 prep of,characterization
R957 T1750 T1751 det these,genes
R958 T1751 T1749 pobj genes,of
R959 T1752 T1751 compound TACC,genes
R960 T1753 T1729 aux could,undertaken
R961 T1754 T1729 neg not,undertaken
R962 T1755 T1729 auxpass be,undertaken
R963 T1756 T1729 punct .,undertaken
R964 T1758 T1759 det No,conclusion
R965 T1759 T1760 nsubjpass conclusion,made
R966 T1761 T1760 aux could,made
R967 T1762 T1760 auxpass be,made
R968 T1763 T1760 prep about,made
R969 T1764 T1765 det the,existence
R970 T1765 T1763 pobj existence,about
R971 T1766 T1765 prep of,existence
R972 T1767 T1768 npadvmod TACC,like
R973 T1768 T1770 amod like,sequence
R974 T1769 T1768 punct -,like
R975 T1770 T1766 pobj sequence,of
R976 T1771 T1765 prep in,existence
R977 T1772 T1773 amod non-bilaterian,metazoans
R978 T1773 T1771 pobj metazoans,in
R979 T1774 T1773 punct ", ",metazoans
R980 T1775 T1776 amod such,as
R981 T1776 T1773 prep as,metazoans
R982 T1777 T1776 pobj Cnidaria,as
R983 T1778 T1777 cc or,Cnidaria
R984 T1779 T1777 conj Porifera,Cnidaria
R985 T1780 T1760 punct ", ",made
R986 T1781 T1760 prep due,made
R987 T1782 T1781 pcomp to,due
R988 T1783 T1784 det the,paucity
R989 T1784 T1781 pobj paucity,due
R990 T1785 T1784 prep of,paucity
R991 T1786 T1787 compound sequence,information
R992 T1787 T1785 pobj information,of
R993 T1788 T1787 prep for,information
R994 T1789 T1790 det these,organisms
R995 T1790 T1788 pobj organisms,for
R996 T1791 T1760 punct ", ",made
R997 T1792 T1760 cc and,made
R998 T1793 T1794 amod additional,sequences
R999 T1794 T1796 nsubjpass sequences,found