craft-sa-dev Home  

PMC:400732 / 11670-12570 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T4023 0-2 IN denotes In
T4025 3-7 DT denotes this
T4026 8-13 NN denotes study
T4027 13-15 , denotes ,
T4028 15-17 PRP denotes we
T4024 18-24 VBD denotes sought
T4029 25-27 TO denotes to
T4030 28-37 VB denotes determine
T4031 38-41 DT denotes the
T4032 42-54 NN denotes contribution
T4033 55-57 IN denotes of
T4034 58-66 NN denotes dopamine
T4035 67-69 NN denotes D2
T4036 70-78 NN denotes receptor
T4038 78-79 HYPH denotes -
T4037 79-87 VBN denotes mediated
T4039 88-97 NN denotes signaling
T4040 98-100 IN denotes to
T4041 101-104 DT denotes the
T4043 105-112 JJ denotes various
T4042 113-119 NNS denotes stages
T4044 120-122 IN denotes of
T4045 123-134 JJ denotes associative
T4047 135-138 CC denotes and
T4048 139-147 NN denotes reversal
T4046 148-156 NN denotes learning
T4049 156-157 . denotes .
T4050 157-414 sentence denotes D2R-/- mice demonstrated that they were capable of learning to locate and consume food pellets, indicating that their locomotor behavior was not detectably disrupted and their primary motivation to obtain a natural reinforcer (food pellet) was undisturbed.
T4051 158-161 NN denotes D2R
T4053 161-162 SYM denotes -
T4054 162-163 HYPH denotes /
T4055 163-164 SYM denotes -
T4052 165-169 NNS denotes mice
T4056 170-182 VBD denotes demonstrated
T4057 183-187 IN denotes that
T4059 188-192 PRP denotes they
T4058 193-197 VBD denotes were
T4060 198-205 JJ denotes capable
T4061 206-208 IN denotes of
T4062 209-217 VBG denotes learning
T4063 218-220 TO denotes to
T4064 221-227 VB denotes locate
T4065 228-231 CC denotes and
T4066 232-239 VB denotes consume
T4067 240-244 NN denotes food
T4068 245-252 NNS denotes pellets
T4069 252-254 , denotes ,
T4070 254-264 VBG denotes indicating
T4071 265-269 IN denotes that
T4073 270-275 PRP$ denotes their
T4075 276-285 NN denotes locomotor
T4074 286-294 NN denotes behavior
T4076 295-298 VBD denotes was
T4077 299-302 RB denotes not
T4078 303-313 RB denotes detectably
T4072 314-323 VBN denotes disrupted
T4079 324-327 CC denotes and
T4080 328-333 PRP$ denotes their
T4082 334-341 JJ denotes primary
T4081 342-352 NN denotes motivation
T4084 353-355 TO denotes to
T4085 356-362 VB denotes obtain
T4086 363-364 DT denotes a
T4088 365-372 JJ denotes natural
T4087 373-383 NN denotes reinforcer
T4089 384-385 -LRB- denotes (
T4090 385-389 NN denotes food
T4091 390-396 NN denotes pellet
T4092 396-397 -RRB- denotes )
T4083 398-401 VBD denotes was
T4093 402-413 JJ denotes undisturbed
T4094 413-414 . denotes .
T4095 414-682 sentence denotes Rather, the impaired ability of D2R-/- mice to assign appropriate discriminative stimulus relationships in an operant discrimination task argues that D2R-mediated signaling contributes to the neuronal processes involved in attaching salience to environmental stimuli.
T4096 415-421 RB denotes Rather
T4098 421-423 , denotes ,
T4099 423-426 DT denotes the
T4101 427-435 JJ denotes impaired
T4100 436-443 NN denotes ability
T4102 444-446 IN denotes of
T4103 447-450 NN denotes D2R
T4105 450-451 SYM denotes -
T4106 451-452 HYPH denotes /
T4107 452-453 SYM denotes -
T4104 454-458 NNS denotes mice
T4108 459-461 TO denotes to
T4109 462-468 VB denotes assign
T4110 469-480 JJ denotes appropriate
T4112 481-495 JJ denotes discriminative
T4113 496-504 NN denotes stimulus
T4111 505-518 NNS denotes relationships
T4114 519-521 IN denotes in
T4115 522-524 DT denotes an
T4117 525-532 NN denotes operant
T4118 533-547 NN denotes discrimination
T4116 548-552 NN denotes task
T4097 553-559 VBZ denotes argues
T4119 560-564 IN denotes that
T4121 565-568 NN denotes D2R
T4123 568-569 HYPH denotes -
T4122 569-577 VBN denotes mediated
T4124 578-587 NN denotes signaling
T4120 588-599 VBZ denotes contributes
T4125 600-602 IN denotes to
T4126 603-606 DT denotes the
T4128 607-615 JJ denotes neuronal
T4127 616-625 NNS denotes processes
T4129 626-634 VBN denotes involved
T4130 635-637 IN denotes in
T4131 638-647 VBG denotes attaching
T4132 648-656 NN denotes salience
T4133 657-659 IN denotes to
T4134 660-673 JJ denotes environmental
T4135 674-681 NNS denotes stimuli
T4136 681-682 . denotes .
T4137 682-900 sentence denotes The deficient capacity of D2R-/- mice to disengage inappropriate decision strategies strongly argues that mesolimbic dopamine signaling, mediated by dopamine D2Rs is essential for efficient reversal learning to occur.
T4138 683-686 DT denotes The
T4140 687-696 JJ denotes deficient
T4139 697-705 NN denotes capacity
T4142 706-708 IN denotes of
T4143 709-712 NN denotes D2R
T4145 712-713 SYM denotes -
T4146 713-714 HYPH denotes /
T4147 714-715 SYM denotes -
T4144 716-720 NNS denotes mice
T4148 721-723 TO denotes to
T4149 724-733 VB denotes disengage
T4150 734-747 JJ denotes inappropriate
T4152 748-756 NN denotes decision
T4151 757-767 NNS denotes strategies
T4153 768-776 RB denotes strongly
T4141 777-783 VBZ denotes argues
T4154 784-788 IN denotes that
T4156 789-799 JJ denotes mesolimbic
T4158 800-808 NN denotes dopamine
T4157 809-818 NN denotes signaling
T4159 818-820 , denotes ,
T4160 820-828 VBN denotes mediated
T4161 829-831 IN denotes by
T4162 832-840 NN denotes dopamine
T4163 841-845 NNS denotes D2Rs
T4155 846-848 VBZ denotes is
T4164 849-858 JJ denotes essential
T4165 859-862 IN denotes for
T4167 863-872 JJ denotes efficient
T4169 873-881 NN denotes reversal
T4168 882-890 NN denotes learning
T4170 891-893 TO denotes to
T4166 894-899 VB denotes occur
T4171 899-900 . denotes .
R2145 T4023 T4024 prep In,sought
R2146 T4025 T4026 det this,study
R2147 T4026 T4023 pobj study,In
R2148 T4027 T4024 punct ", ",sought
R2149 T4028 T4024 nsubj we,sought
R2150 T4029 T4030 aux to,determine
R2151 T4030 T4024 xcomp determine,sought
R2152 T4031 T4032 det the,contribution
R2153 T4032 T4030 dobj contribution,determine
R2154 T4033 T4032 prep of,contribution
R2155 T4034 T4035 compound dopamine,D2
R2156 T4035 T4036 compound D2,receptor
R2157 T4036 T4037 npadvmod receptor,mediated
R2158 T4037 T4039 amod mediated,signaling
R2159 T4038 T4037 punct -,mediated
R2160 T4039 T4033 pobj signaling,of
R2161 T4040 T4032 prep to,contribution
R2162 T4041 T4042 det the,stages
R2163 T4042 T4040 pobj stages,to
R2164 T4043 T4042 amod various,stages
R2165 T4044 T4042 prep of,stages
R2166 T4045 T4046 amod associative,learning
R2167 T4046 T4044 pobj learning,of
R2168 T4047 T4045 cc and,associative
R2169 T4048 T4045 conj reversal,associative
R2170 T4049 T4024 punct .,sought
R2171 T4051 T4052 nmod D2R,mice
R2172 T4052 T4056 nsubj mice,demonstrated
R2173 T4053 T4051 punct -,D2R
R2174 T4054 T4051 punct /,D2R
R2175 T4055 T4051 punct -,D2R
R2176 T4057 T4058 mark that,were
R2177 T4058 T4056 ccomp were,demonstrated
R2178 T4059 T4058 nsubj they,were
R2179 T4060 T4058 acomp capable,were
R2180 T4061 T4060 prep of,capable
R2181 T4062 T4061 pcomp learning,of
R2182 T4063 T4064 aux to,locate
R2183 T4064 T4062 xcomp locate,learning
R2184 T4065 T4064 cc and,locate
R2185 T4066 T4064 conj consume,locate
R2186 T4067 T4068 compound food,pellets
R2187 T4068 T4066 dobj pellets,consume
R2188 T4069 T4056 punct ", ",demonstrated
R2189 T4070 T4056 advcl indicating,demonstrated
R2190 T4071 T4072 mark that,disrupted
R2191 T4072 T4070 ccomp disrupted,indicating
R2192 T4073 T4074 poss their,behavior
R2193 T4074 T4072 nsubjpass behavior,disrupted
R2194 T4075 T4074 compound locomotor,behavior
R2195 T4076 T4072 auxpass was,disrupted
R2196 T4077 T4072 neg not,disrupted
R2197 T4078 T4072 advmod detectably,disrupted
R2198 T4079 T4072 cc and,disrupted
R2199 T4080 T4081 poss their,motivation
R2200 T4081 T4083 nsubj motivation,was
R2201 T4082 T4081 amod primary,motivation
R2202 T4083 T4072 conj was,disrupted
R2203 T4084 T4085 aux to,obtain
R2204 T4085 T4081 acl obtain,motivation
R2205 T4086 T4087 det a,reinforcer
R2206 T4087 T4085 dobj reinforcer,obtain
R2207 T4088 T4087 amod natural,reinforcer
R2208 T4089 T4087 punct (,reinforcer
R2209 T4090 T4091 compound food,pellet
R2210 T4091 T4087 appos pellet,reinforcer
R2211 T4092 T4087 punct ),reinforcer
R2212 T4093 T4083 acomp undisturbed,was
R2213 T4094 T4056 punct .,demonstrated
R2214 T4096 T4097 advmod Rather,argues
R2215 T4098 T4097 punct ", ",argues
R2216 T4099 T4100 det the,ability
R2217 T4100 T4097 nsubj ability,argues
R2218 T4101 T4100 amod impaired,ability
R2219 T4102 T4100 prep of,ability
R2220 T4103 T4104 nmod D2R,mice
R2221 T4104 T4102 pobj mice,of
R2222 T4105 T4103 punct -,D2R
R2223 T4106 T4103 punct /,D2R
R2224 T4107 T4103 punct -,D2R
R2225 T4108 T4109 aux to,assign
R2226 T4109 T4100 acl assign,ability
R2227 T4110 T4111 amod appropriate,relationships
R2228 T4111 T4109 dobj relationships,assign
R2229 T4112 T4113 amod discriminative,stimulus
R2230 T4113 T4111 compound stimulus,relationships
R2231 T4114 T4109 prep in,assign
R2232 T4115 T4116 det an,task
R2233 T4116 T4114 pobj task,in
R2234 T4117 T4116 compound operant,task
R2235 T4118 T4116 compound discrimination,task
R2236 T4119 T4120 mark that,contributes
R2237 T4120 T4097 ccomp contributes,argues
R2238 T4121 T4122 npadvmod D2R,mediated
R2239 T4122 T4124 amod mediated,signaling
R2240 T4123 T4122 punct -,mediated
R2241 T4124 T4120 nsubj signaling,contributes
R2242 T4125 T4120 prep to,contributes
R2243 T4126 T4127 det the,processes
R2244 T4127 T4125 pobj processes,to
R2245 T4128 T4127 amod neuronal,processes
R2246 T4129 T4127 acl involved,processes
R2247 T4130 T4129 prep in,involved
R2248 T4131 T4130 pcomp attaching,in
R2249 T4132 T4131 dobj salience,attaching
R2250 T4133 T4131 prep to,attaching
R2251 T4134 T4135 amod environmental,stimuli
R2252 T4135 T4133 pobj stimuli,to
R2253 T4136 T4097 punct .,argues
R2254 T4138 T4139 det The,capacity
R2255 T4139 T4141 nsubj capacity,argues
R2256 T4140 T4139 amod deficient,capacity
R2257 T4142 T4139 prep of,capacity
R2258 T4143 T4144 nmod D2R,mice
R2259 T4144 T4142 pobj mice,of
R2260 T4145 T4143 punct -,D2R
R2261 T4146 T4143 punct /,D2R
R2262 T4147 T4143 punct -,D2R
R2263 T4148 T4149 aux to,disengage
R2264 T4149 T4139 acl disengage,capacity
R2265 T4150 T4151 amod inappropriate,strategies
R2266 T4151 T4149 dobj strategies,disengage
R2267 T4152 T4151 compound decision,strategies
R2268 T4153 T4141 advmod strongly,argues
R2269 T4154 T4155 mark that,is
R2270 T4155 T4141 ccomp is,argues
R2271 T4156 T4157 amod mesolimbic,signaling
R2272 T4157 T4155 nsubj signaling,is
R2273 T4158 T4157 compound dopamine,signaling
R2274 T4159 T4157 punct ", ",signaling
R2275 T4160 T4157 acl mediated,signaling
R2276 T4161 T4160 agent by,mediated
R2277 T4162 T4163 compound dopamine,D2Rs
R2278 T4163 T4161 pobj D2Rs,by
R2279 T4164 T4155 acomp essential,is
R2280 T4165 T4166 mark for,occur
R2281 T4166 T4155 advcl occur,is
R2282 T4167 T4168 amod efficient,learning
R2283 T4168 T4166 nsubj learning,occur
R2284 T4169 T4168 compound reversal,learning
R2285 T4170 T4166 aux to,occur
R2286 T4171 T4141 punct .,argues