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PMC:314463 / 41361-43314 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T8500 0-5 VBN denotes Named
T8502 6-9 IN denotes for
T8503 10-13 DT denotes the
T8504 14-22 NN denotes presence
T8505 23-25 IN denotes of
T8506 26-27 DT denotes a
T8508 28-31 NN denotes DNA
T8510 31-32 HYPH denotes -
T8509 32-39 VBG denotes binding
T8507 40-46 NN denotes domain
T8511 47-52 RB denotes first
T8512 53-63 VBN denotes identified
T8513 64-66 IN denotes in
T8514 67-70 DT denotes the
T8516 71-76 NN denotes mouse
T8517 77-86 NN denotes Brachyury
T8515 87-91 NN denotes gene
T8518 92-93 -LRB- denotes (
T8520 93-111 NN denotes haploinsufficiency
T8519 112-118 VBZ denotes causes
T8521 119-120 DT denotes a
T8523 121-126 JJ denotes short
T8522 127-131 NN denotes tail
T8524 131-132 -RRB- denotes )
T8525 132-134 , denotes ,
T8526 134-135 NN denotes T
T8527 136-139 NN denotes box
T8529 139-140 HYPH denotes –
T8528 140-150 VBG denotes containing
T8530 151-156 NNS denotes genes
T8531 157-161 VBP denotes have
T8532 162-166 VBN denotes been
T8501 167-177 VBN denotes identified
T8533 178-180 IN denotes as
T8534 181-194 JJ denotes developmental
T8535 195-205 NNS denotes regulators
T8536 206-208 IN denotes in
T8537 209-210 DT denotes a
T8539 211-215 JJ denotes wide
T8538 216-224 NN denotes spectrum
T8540 225-227 IN denotes of
T8541 228-235 NNS denotes tissues
T8542 236-239 CC denotes and
T8543 240-253 JJ denotes multicellular
T8544 254-263 NNS denotes organisms
T8545 264-265 -LRB- denotes (
T8546 265-273 VBN denotes reviewed
T8547 274-276 IN denotes in
T8548 277-288 NNP denotes Papaioannou
T8549 289-293 CD denotes 2001
T8550 293-294 -RRB- denotes )
T8551 294-295 . denotes .
T8552 295-517 sentence denotes The Tbx15 subfamily, which also includes Tbx18 and Tbx22, is likely to have arisen during early chordate evolution since there is a single gene in amphioxus but no obvious homolog in the fly genome (Ruvinsky et al. 2000).
T8553 296-299 DT denotes The
T8555 300-305 NN denotes Tbx15
T8554 306-315 NN denotes subfamily
T8557 315-317 , denotes ,
T8558 317-322 WDT denotes which
T8560 323-327 RB denotes also
T8559 328-336 VBZ denotes includes
T8561 337-342 NN denotes Tbx18
T8562 343-346 CC denotes and
T8563 347-352 NN denotes Tbx22
T8564 352-354 , denotes ,
T8556 354-356 VBZ denotes is
T8565 357-363 JJ denotes likely
T8566 364-366 TO denotes to
T8568 367-371 VB denotes have
T8567 372-378 VBN denotes arisen
T8569 379-385 IN denotes during
T8570 386-391 JJ denotes early
T8572 392-400 NN denotes chordate
T8571 401-410 NN denotes evolution
T8573 411-416 IN denotes since
T8575 417-422 EX denotes there
T8574 423-425 VBZ denotes is
T8576 426-427 DT denotes a
T8578 428-434 JJ denotes single
T8577 435-439 NN denotes gene
T8579 440-442 IN denotes in
T8580 443-452 NN denotes amphioxus
T8581 453-456 CC denotes but
T8582 457-459 DT denotes no
T8584 460-467 JJ denotes obvious
T8583 468-475 NN denotes homolog
T8585 476-478 IN denotes in
T8586 479-482 DT denotes the
T8588 483-486 NN denotes fly
T8587 487-493 NN denotes genome
T8589 494-495 -LRB- denotes (
T8590 495-503 NNP denotes Ruvinsky
T8591 504-506 FW denotes et
T8592 507-510 FW denotes al.
T8593 511-515 CD denotes 2000
T8594 515-516 -RRB- denotes )
T8595 516-517 . denotes .
T8596 517-887 sentence denotes Consistent with this relationship, the three genes are expressed in partially overlapping patterns that include anterior somites (Tbx18 and Tbx22), limb mesenchyme (Tbx15 and Tbx18), and craniofacial mesenchyme (all three genes, Tbx15 more broadly than Tbx18 or Tbx22) (Agulnik et al. 1998; Kraus et al. 2001; Braybrook et al. 2002; Bush et al. 2002; Herr et al. 2003).
T8597 518-528 JJ denotes Consistent
T8599 529-533 IN denotes with
T8600 534-538 DT denotes this
T8601 539-551 NN denotes relationship
T8602 551-553 , denotes ,
T8603 553-556 DT denotes the
T8605 557-562 CD denotes three
T8604 563-568 NNS denotes genes
T8606 569-572 VBP denotes are
T8598 573-582 VBN denotes expressed
T8607 583-585 IN denotes in
T8608 586-595 RB denotes partially
T8609 596-607 VBG denotes overlapping
T8610 608-616 NNS denotes patterns
T8611 617-621 WDT denotes that
T8612 622-629 VBP denotes include
T8613 630-638 JJ denotes anterior
T8614 639-646 NNS denotes somites
T8615 647-648 -LRB- denotes (
T8616 648-653 NN denotes Tbx18
T8617 654-657 CC denotes and
T8618 658-663 NN denotes Tbx22
T8619 663-664 -RRB- denotes )
T8620 664-666 , denotes ,
T8621 666-670 NN denotes limb
T8622 671-681 NN denotes mesenchyme
T8623 682-683 -LRB- denotes (
T8624 683-688 NN denotes Tbx15
T8625 689-692 CC denotes and
T8626 693-698 NN denotes Tbx18
T8627 698-699 -RRB- denotes )
T8628 699-701 , denotes ,
T8629 701-704 CC denotes and
T8630 705-717 JJ denotes craniofacial
T8631 718-728 NN denotes mesenchyme
T8632 729-730 -LRB- denotes (
T8634 730-733 DT denotes all
T8635 734-739 CD denotes three
T8633 740-745 NNS denotes genes
T8636 745-747 , denotes ,
T8637 747-752 NN denotes Tbx15
T8638 753-757 RBR denotes more
T8639 758-765 RB denotes broadly
T8640 766-770 IN denotes than
T8641 771-776 NN denotes Tbx18
T8642 777-779 CC denotes or
T8643 780-785 NN denotes Tbx22
T8644 785-786 -RRB- denotes )
T8645 787-788 -LRB- denotes (
T8646 788-795 NNP denotes Agulnik
T8647 796-798 FW denotes et
T8648 799-802 FW denotes al.
T8649 803-807 CD denotes 1998
T8650 807-808 : denotes ;
T8651 809-814 NNP denotes Kraus
T8652 815-817 FW denotes et
T8653 818-821 FW denotes al.
T8654 822-826 CD denotes 2001
T8655 826-827 : denotes ;
T8656 828-837 NNP denotes Braybrook
T8657 838-840 FW denotes et
T8658 841-844 FW denotes al.
T8659 845-849 CD denotes 2002
T8660 849-850 : denotes ;
T8661 851-855 NNP denotes Bush
T8662 856-858 FW denotes et
T8663 859-862 FW denotes al.
T8664 863-867 CD denotes 2002
T8665 867-868 : denotes ;
T8666 869-873 NNP denotes Herr
T8667 874-876 FW denotes et
T8668 877-880 FW denotes al.
T8669 881-885 CD denotes 2003
T8670 885-886 -RRB- denotes )
T8671 886-887 . denotes .
T8672 887-1179 sentence denotes These observations suggest that an ancestral gene for Tbx15, Tbx18, and Tbx22 may have been important for craniofacial development in cephalochordates, with acquisition of additional expression patterns and developmental functions in the limb and the trunk during early vertebrate evolution.
T8673 888-893 DT denotes These
T8674 894-906 NNS denotes observations
T8675 907-914 VBP denotes suggest
T8676 915-919 IN denotes that
T8678 920-922 DT denotes an
T8680 923-932 JJ denotes ancestral
T8679 933-937 NN denotes gene
T8681 938-941 IN denotes for
T8682 942-947 NN denotes Tbx15
T8683 947-949 , denotes ,
T8684 949-954 NN denotes Tbx18
T8685 954-956 , denotes ,
T8686 956-959 CC denotes and
T8687 960-965 NN denotes Tbx22
T8688 966-969 MD denotes may
T8689 970-974 VB denotes have
T8677 975-979 VBN denotes been
T8690 980-989 JJ denotes important
T8691 990-993 IN denotes for
T8692 994-1006 JJ denotes craniofacial
T8693 1007-1018 NN denotes development
T8694 1019-1021 IN denotes in
T8695 1022-1038 NNS denotes cephalochordates
T8696 1038-1040 , denotes ,
T8697 1040-1044 IN denotes with
T8698 1045-1056 NN denotes acquisition
T8699 1057-1059 IN denotes of
T8700 1060-1070 JJ denotes additional
T8702 1071-1081 NN denotes expression
T8701 1082-1090 NNS denotes patterns
T8703 1091-1094 CC denotes and
T8704 1095-1108 JJ denotes developmental
T8705 1109-1118 NNS denotes functions
T8706 1119-1121 IN denotes in
T8707 1122-1125 DT denotes the
T8708 1126-1130 NN denotes limb
T8709 1131-1134 CC denotes and
T8710 1135-1138 DT denotes the
T8711 1139-1144 NN denotes trunk
T8712 1145-1151 IN denotes during
T8713 1152-1157 JJ denotes early
T8715 1158-1168 NN denotes vertebrate
T8714 1169-1178 NN denotes evolution
T8716 1178-1179 . denotes .
T8717 1179-1379 sentence denotes Expression of Tbx18 and Tbx22 has not been reported in embryonic flank mesenchyme, which suggests that Tbx15 is the only family member involved in establishing the dorsoventral identity of the trunk.
T8718 1180-1190 NN denotes Expression
T8720 1191-1193 IN denotes of
T8721 1194-1199 NN denotes Tbx18
T8722 1200-1203 CC denotes and
T8723 1204-1209 NN denotes Tbx22
T8724 1210-1213 VBZ denotes has
T8725 1214-1217 RB denotes not
T8726 1218-1222 VBN denotes been
T8719 1223-1231 VBN denotes reported
T8727 1232-1234 IN denotes in
T8728 1235-1244 JJ denotes embryonic
T8730 1245-1250 NN denotes flank
T8729 1251-1261 NN denotes mesenchyme
T8731 1261-1263 , denotes ,
T8732 1263-1268 WDT denotes which
T8733 1269-1277 VBZ denotes suggests
T8734 1278-1282 IN denotes that
T8736 1283-1288 NN denotes Tbx15
T8735 1289-1291 VBZ denotes is
T8737 1292-1295 DT denotes the
T8739 1296-1300 JJ denotes only
T8740 1301-1307 NN denotes family
T8738 1308-1314 NN denotes member
T8741 1315-1323 VBN denotes involved
T8742 1324-1326 IN denotes in
T8743 1327-1339 VBG denotes establishing
T8744 1340-1343 DT denotes the
T8746 1344-1356 JJ denotes dorsoventral
T8745 1357-1365 NN denotes identity
T8747 1366-1368 IN denotes of
T8748 1369-1372 DT denotes the
T8749 1373-1378 NN denotes trunk
T8750 1378-1379 . denotes .
T8751 1379-1581 sentence denotes However, it would not be surprising to find some degree of functional redundancy in animals mutated for two or three of the subfamily members in other body regions, particularly the limbs and the head.
T8752 1380-1387 RB denotes However
T8754 1387-1389 , denotes ,
T8755 1389-1391 PRP denotes it
T8756 1392-1397 MD denotes would
T8757 1398-1401 RB denotes not
T8753 1402-1404 VB denotes be
T8758 1405-1415 JJ denotes surprising
T8759 1416-1418 TO denotes to
T8760 1419-1423 VB denotes find
T8761 1424-1428 DT denotes some
T8762 1429-1435 NN denotes degree
T8763 1436-1438 IN denotes of
T8764 1439-1449 JJ denotes functional
T8765 1450-1460 NN denotes redundancy
T8766 1461-1463 IN denotes in
T8767 1464-1471 NNS denotes animals
T8768 1472-1479 VBN denotes mutated
T8769 1480-1483 IN denotes for
T8770 1484-1487 CD denotes two
T8771 1488-1490 CC denotes or
T8772 1491-1496 CD denotes three
T8773 1497-1499 IN denotes of
T8774 1500-1503 DT denotes the
T8776 1504-1513 NN denotes subfamily
T8775 1514-1521 NNS denotes members
T8777 1522-1524 IN denotes in
T8778 1525-1530 JJ denotes other
T8780 1531-1535 NN denotes body
T8779 1536-1543 NNS denotes regions
T8781 1543-1545 , denotes ,
T8782 1545-1557 RB denotes particularly
T8784 1558-1561 DT denotes the
T8783 1562-1567 NNS denotes limbs
T8785 1568-1571 CC denotes and
T8786 1572-1575 DT denotes the
T8787 1576-1580 NN denotes head
T8788 1580-1581 . denotes .
T8789 1581-1703 sentence denotes For example, mutations in Tbx22 cause the human syndrome X-linked cleft palate and ankyloglossia (Braybrook et al. 2001).
T8790 1582-1585 IN denotes For
T8792 1586-1593 NN denotes example
T8793 1593-1595 , denotes ,
T8794 1595-1604 NNS denotes mutations
T8795 1605-1607 IN denotes in
T8796 1608-1613 NN denotes Tbx22
T8791 1614-1619 VBP denotes cause
T8797 1620-1623 DT denotes the
T8799 1624-1629 JJ denotes human
T8798 1630-1638 NN denotes syndrome
T8800 1639-1640 NN denotes X
T8802 1640-1641 HYPH denotes -
T8801 1641-1647 VBN denotes linked
T8804 1648-1653 JJ denotes cleft
T8803 1654-1660 NN denotes palate
T8805 1661-1664 CC denotes and
T8806 1665-1678 NN denotes ankyloglossia
T8807 1679-1680 -LRB- denotes (
T8808 1680-1689 NNP denotes Braybrook
T8809 1690-1692 FW denotes et
T8810 1693-1696 FW denotes al.
T8811 1697-1701 CD denotes 2001
T8812 1701-1702 -RRB- denotes )
T8813 1702-1703 . denotes .
T8814 1703-1953 sentence denotes Despite high levels of Tbx22 expression in periocular embryonic mesenchyme (Braybrook et al. 2002; Bush et al. 2002; Herr et al. 2003), the condition does not affect the eye, perhaps because residual activity is provided by Tbx15 in the same region.
T8815 1704-1711 IN denotes Despite
T8817 1712-1716 JJ denotes high
T8818 1717-1723 NNS denotes levels
T8819 1724-1726 IN denotes of
T8820 1727-1732 NN denotes Tbx22
T8821 1733-1743 NN denotes expression
T8822 1744-1746 IN denotes in
T8823 1747-1757 JJ denotes periocular
T8825 1758-1767 JJ denotes embryonic
T8824 1768-1778 NN denotes mesenchyme
T8826 1779-1780 -LRB- denotes (
T8827 1780-1789 NNP denotes Braybrook
T8828 1790-1792 FW denotes et
T8829 1793-1796 FW denotes al.
T8830 1797-1801 CD denotes 2002
T8831 1801-1802 : denotes ;
T8832 1803-1807 NNP denotes Bush
T8833 1808-1810 FW denotes et
T8834 1811-1814 FW denotes al.
T8835 1815-1819 CD denotes 2002
T8836 1819-1820 : denotes ;
T8837 1821-1825 NNP denotes Herr
T8838 1826-1828 FW denotes et
T8839 1829-1832 FW denotes al.
T8840 1833-1837 CD denotes 2003
T8841 1837-1838 -RRB- denotes )
T8842 1838-1840 , denotes ,
T8843 1840-1843 DT denotes the
T8844 1844-1853 NN denotes condition
T8845 1854-1858 VBZ denotes does
T8846 1859-1862 RB denotes not
T8816 1863-1869 VB denotes affect
T8847 1870-1873 DT denotes the
T8848 1874-1877 NN denotes eye
T8849 1877-1879 , denotes ,
T8850 1879-1886 RB denotes perhaps
T8852 1887-1894 IN denotes because
T8853 1895-1903 JJ denotes residual
T8854 1904-1912 NN denotes activity
T8855 1913-1915 VBZ denotes is
T8851 1916-1924 VBN denotes provided
T8856 1925-1927 IN denotes by
T8857 1928-1933 NN denotes Tbx15
T8858 1934-1936 IN denotes in
T8859 1937-1940 DT denotes the
T8861 1941-1945 JJ denotes same
T8860 1946-1952 NN denotes region
T8862 1952-1953 . denotes .
R5789 T8500 T8501 advcl Named,identified
R5790 T8502 T8500 prep for,Named
R5791 T8503 T8504 det the,presence
R5792 T8504 T8502 pobj presence,for
R5793 T8505 T8504 prep of,presence
R5794 T8506 T8507 det a,domain
R5795 T8507 T8505 pobj domain,of
R5796 T8508 T8509 npadvmod DNA,binding
R5797 T8509 T8507 amod binding,domain
R5798 T8510 T8509 punct -,binding
R5799 T8511 T8512 advmod first,identified
R5800 T8512 T8507 acl identified,domain
R5801 T8513 T8512 prep in,identified
R5802 T8514 T8515 det the,gene
R5803 T8515 T8513 pobj gene,in
R5804 T8516 T8515 compound mouse,gene
R5805 T8517 T8515 compound Brachyury,gene
R5806 T8518 T8519 punct (,causes
R5807 T8519 T8500 parataxis causes,Named
R5808 T8520 T8519 nsubj haploinsufficiency,causes
R5809 T8521 T8522 det a,tail
R5810 T8522 T8519 dobj tail,causes
R5811 T8523 T8522 amod short,tail
R5812 T8524 T8519 punct ),causes
R5813 T8525 T8501 punct ", ",identified
R5814 T8526 T8527 compound T,box
R5815 T8527 T8528 npadvmod box,containing
R5816 T8528 T8530 amod containing,genes
R5817 T8529 T8528 punct –,containing
R5818 T8530 T8501 nsubjpass genes,identified
R5819 T8531 T8501 aux have,identified
R5820 T8532 T8501 auxpass been,identified
R5821 T8533 T8501 prep as,identified
R5822 T8534 T8535 amod developmental,regulators
R5823 T8535 T8533 pobj regulators,as
R5824 T8536 T8501 prep in,identified
R5825 T8537 T8538 det a,spectrum
R5826 T8538 T8536 pobj spectrum,in
R5827 T8539 T8538 amod wide,spectrum
R5828 T8540 T8538 prep of,spectrum
R5829 T8541 T8540 pobj tissues,of
R5830 T8542 T8541 cc and,tissues
R5831 T8543 T8544 amod multicellular,organisms
R5832 T8544 T8541 conj organisms,tissues
R5833 T8545 T8546 punct (,reviewed
R5834 T8546 T8501 parataxis reviewed,identified
R5835 T8547 T8546 prep in,reviewed
R5836 T8548 T8547 pobj Papaioannou,in
R5837 T8549 T8548 npadvmod 2001,Papaioannou
R5838 T8550 T8546 punct ),reviewed
R5839 T8551 T8501 punct .,identified
R5840 T8553 T8554 det The,subfamily
R5841 T8554 T8556 nsubj subfamily,is
R5842 T8555 T8554 compound Tbx15,subfamily
R5843 T8557 T8554 punct ", ",subfamily
R5844 T8558 T8559 dep which,includes
R5845 T8559 T8554 relcl includes,subfamily
R5846 T8560 T8559 advmod also,includes
R5847 T8561 T8559 dobj Tbx18,includes
R5848 T8562 T8561 cc and,Tbx18
R5849 T8563 T8561 conj Tbx22,Tbx18
R5850 T8564 T8556 punct ", ",is
R5851 T8565 T8556 acomp likely,is
R5852 T8566 T8567 aux to,arisen
R5853 T8567 T8565 xcomp arisen,likely
R5854 T8568 T8567 aux have,arisen
R5855 T8569 T8567 prep during,arisen
R5856 T8570 T8571 amod early,evolution
R5857 T8571 T8569 pobj evolution,during
R5858 T8572 T8571 compound chordate,evolution
R5859 T8573 T8574 mark since,is
R5860 T8574 T8567 advcl is,arisen
R5861 T8575 T8574 expl there,is
R5862 T8576 T8577 det a,gene
R5863 T8577 T8574 attr gene,is
R5864 T8578 T8577 amod single,gene
R5865 T8579 T8577 prep in,gene
R5866 T8580 T8579 pobj amphioxus,in
R5867 T8581 T8577 cc but,gene
R5868 T8582 T8583 det no,homolog
R5869 T8583 T8577 conj homolog,gene
R5870 T8584 T8583 amod obvious,homolog
R5871 T8585 T8583 prep in,homolog
R5872 T8586 T8587 det the,genome
R5873 T8587 T8585 pobj genome,in
R5874 T8588 T8587 compound fly,genome
R5875 T8589 T8590 punct (,Ruvinsky
R5876 T8590 T8574 meta Ruvinsky,is
R5877 T8591 T8590 nmod et,Ruvinsky
R5878 T8592 T8590 nmod al.,Ruvinsky
R5879 T8593 T8590 nummod 2000,Ruvinsky
R5880 T8594 T8590 punct ),Ruvinsky
R5881 T8595 T8556 punct .,is
R5882 T8597 T8598 advcl Consistent,expressed
R5883 T8599 T8597 prep with,Consistent
R5884 T8600 T8601 det this,relationship
R5885 T8601 T8599 pobj relationship,with
R5886 T8602 T8598 punct ", ",expressed
R5887 T8603 T8604 det the,genes
R5888 T8604 T8598 nsubjpass genes,expressed
R5889 T8605 T8604 nummod three,genes
R5890 T8606 T8598 auxpass are,expressed
R5891 T8607 T8598 prep in,expressed
R5892 T8608 T8609 advmod partially,overlapping
R5893 T8609 T8610 amod overlapping,patterns
R5894 T8610 T8607 pobj patterns,in
R5895 T8611 T8612 dep that,include
R5896 T8612 T8610 relcl include,patterns
R5897 T8613 T8614 amod anterior,somites
R5898 T8614 T8612 dobj somites,include
R5899 T8615 T8616 punct (,Tbx18
R5900 T8616 T8614 parataxis Tbx18,somites
R5901 T8617 T8616 cc and,Tbx18
R5902 T8618 T8616 conj Tbx22,Tbx18
R5903 T8619 T8616 punct ),Tbx18
R5904 T8620 T8614 punct ", ",somites
R5905 T8621 T8622 compound limb,mesenchyme
R5906 T8622 T8614 conj mesenchyme,somites
R5907 T8623 T8624 punct (,Tbx15
R5908 T8624 T8622 parataxis Tbx15,mesenchyme
R5909 T8625 T8624 cc and,Tbx15
R5910 T8626 T8624 conj Tbx18,Tbx15
R5911 T8627 T8624 punct ),Tbx15
R5912 T8628 T8622 punct ", ",mesenchyme
R5913 T8629 T8622 cc and,mesenchyme
R5914 T8630 T8631 amod craniofacial,mesenchyme
R5915 T8631 T8622 conj mesenchyme,mesenchyme
R5916 T8632 T8633 punct (,genes
R5917 T8633 T8631 parataxis genes,mesenchyme
R5918 T8634 T8633 det all,genes
R5919 T8635 T8633 nummod three,genes
R5920 T8636 T8633 punct ", ",genes
R5921 T8637 T8633 dep Tbx15,genes
R5922 T8638 T8639 advmod more,broadly
R5923 T8639 T8637 advmod broadly,Tbx15
R5924 T8640 T8639 prep than,broadly
R5925 T8641 T8640 pobj Tbx18,than
R5926 T8642 T8641 cc or,Tbx18
R5927 T8643 T8641 conj Tbx22,Tbx18
R5928 T8644 T8633 punct ),genes
R5929 T8645 T8646 punct (,Agulnik
R5930 T8646 T8612 meta Agulnik,include
R5931 T8647 T8646 nmod et,Agulnik
R5932 T8648 T8646 nmod al.,Agulnik
R5933 T8649 T8646 nummod 1998,Agulnik
R5934 T8650 T8646 punct ;,Agulnik
R5935 T8651 T8646 nmod Kraus,Agulnik
R5936 T8652 T8646 nmod et,Agulnik
R5937 T8653 T8646 nmod al.,Agulnik
R5938 T8654 T8646 nummod 2001,Agulnik
R5939 T8655 T8646 punct ;,Agulnik
R5940 T8656 T8646 nmod Braybrook,Agulnik
R5941 T8657 T8646 nmod et,Agulnik
R5942 T8658 T8646 nmod al.,Agulnik
R5943 T8659 T8646 nummod 2002,Agulnik
R5944 T8660 T8646 punct ;,Agulnik
R5945 T8661 T8646 nmod Bush,Agulnik
R5946 T8662 T8646 nmod et,Agulnik
R5947 T8663 T8646 nmod al.,Agulnik
R5948 T8664 T8646 nummod 2002,Agulnik
R5949 T8665 T8646 punct ;,Agulnik
R5950 T8666 T8646 nmod Herr,Agulnik
R5951 T8667 T8646 nmod et,Agulnik
R5952 T8668 T8646 nmod al.,Agulnik
R5953 T8669 T8646 nummod 2003,Agulnik
R5954 T8670 T8646 punct ),Agulnik
R5955 T8671 T8598 punct .,expressed
R5956 T8673 T8674 det These,observations
R5957 T8674 T8675 nsubj observations,suggest
R5958 T8676 T8677 mark that,been
R5959 T8677 T8675 ccomp been,suggest
R5960 T8678 T8679 det an,gene
R5961 T8679 T8677 nsubj gene,been
R5962 T8680 T8679 amod ancestral,gene
R5963 T8681 T8679 prep for,gene
R5964 T8682 T8681 pobj Tbx15,for
R5965 T8683 T8682 punct ", ",Tbx15
R5966 T8684 T8682 conj Tbx18,Tbx15
R5967 T8685 T8684 punct ", ",Tbx18
R5968 T8686 T8684 cc and,Tbx18
R5969 T8687 T8684 conj Tbx22,Tbx18
R5970 T8688 T8677 aux may,been
R5971 T8689 T8677 aux have,been
R5972 T8690 T8677 acomp important,been
R5973 T8691 T8677 prep for,been
R5974 T8692 T8693 amod craniofacial,development
R5975 T8693 T8691 pobj development,for
R5976 T8694 T8693 prep in,development
R5977 T8695 T8694 pobj cephalochordates,in
R5978 T8696 T8677 punct ", ",been
R5979 T8697 T8677 prep with,been
R5980 T8698 T8697 pobj acquisition,with
R5981 T8699 T8698 prep of,acquisition
R5982 T8700 T8701 amod additional,patterns
R5983 T8701 T8699 pobj patterns,of
R5984 T8702 T8701 compound expression,patterns
R5985 T8703 T8701 cc and,patterns
R5986 T8704 T8705 amod developmental,functions
R5987 T8705 T8701 conj functions,patterns
R5988 T8706 T8698 prep in,acquisition
R5989 T8707 T8708 det the,limb
R5990 T8708 T8706 pobj limb,in
R5991 T8709 T8708 cc and,limb
R5992 T8710 T8711 det the,trunk
R5993 T8711 T8708 conj trunk,limb
R5994 T8712 T8698 prep during,acquisition
R5995 T8713 T8714 amod early,evolution
R5996 T8714 T8712 pobj evolution,during
R5997 T8715 T8714 compound vertebrate,evolution
R5998 T8716 T8675 punct .,suggest
R5999 T8718 T8719 nsubjpass Expression,reported
R6000 T8720 T8718 prep of,Expression
R6001 T8721 T8720 pobj Tbx18,of
R6002 T8722 T8721 cc and,Tbx18
R6003 T8723 T8721 conj Tbx22,Tbx18
R6004 T8724 T8719 aux has,reported
R6005 T8725 T8719 neg not,reported
R6006 T8726 T8719 auxpass been,reported
R6007 T8727 T8719 prep in,reported
R6008 T8728 T8729 amod embryonic,mesenchyme
R6009 T8729 T8727 pobj mesenchyme,in
R6010 T8730 T8729 compound flank,mesenchyme
R6011 T8731 T8719 punct ", ",reported
R6012 T8732 T8733 dep which,suggests
R6013 T8733 T8719 advcl suggests,reported
R6014 T8734 T8735 mark that,is
R6015 T8735 T8733 ccomp is,suggests
R6016 T8736 T8735 nsubj Tbx15,is
R6017 T8737 T8738 det the,member
R6018 T8738 T8735 attr member,is
R6019 T8739 T8738 amod only,member
R6020 T8740 T8738 compound family,member
R6021 T8741 T8738 acl involved,member
R6022 T8742 T8741 prep in,involved
R6023 T8743 T8742 pcomp establishing,in
R6024 T8744 T8745 det the,identity
R6025 T8745 T8743 dobj identity,establishing
R6026 T8746 T8745 amod dorsoventral,identity
R6027 T8747 T8745 prep of,identity
R6028 T8748 T8749 det the,trunk
R6029 T8749 T8747 pobj trunk,of
R6030 T8750 T8719 punct .,reported
R6031 T8752 T8753 advmod However,be
R6032 T8754 T8753 punct ", ",be
R6033 T8755 T8753 nsubj it,be
R6034 T8756 T8753 aux would,be
R6035 T8757 T8753 neg not,be
R6036 T8758 T8753 acomp surprising,be
R6037 T8759 T8760 aux to,find
R6038 T8760 T8753 xcomp find,be
R6039 T8761 T8762 det some,degree
R6040 T8762 T8760 dobj degree,find
R6041 T8763 T8762 prep of,degree
R6042 T8764 T8765 amod functional,redundancy
R6043 T8765 T8763 pobj redundancy,of
R6044 T8766 T8760 prep in,find
R6045 T8767 T8766 pobj animals,in
R6046 T8768 T8767 acl mutated,animals
R6047 T8769 T8768 prep for,mutated
R6048 T8770 T8769 pobj two,for
R6049 T8771 T8770 cc or,two
R6050 T8772 T8770 conj three,two
R6051 T8773 T8770 prep of,two
R6052 T8774 T8775 det the,members
R6053 T8775 T8773 pobj members,of
R6054 T8776 T8775 compound subfamily,members
R6055 T8777 T8760 prep in,find
R6056 T8778 T8779 amod other,regions
R6057 T8779 T8777 pobj regions,in
R6058 T8780 T8779 compound body,regions
R6059 T8781 T8779 punct ", ",regions
R6060 T8782 T8783 advmod particularly,limbs
R6061 T8783 T8779 appos limbs,regions
R6062 T8784 T8783 det the,limbs
R6063 T8785 T8783 cc and,limbs
R6064 T8786 T8787 det the,head
R6065 T8787 T8783 conj head,limbs
R6066 T8788 T8753 punct .,be
R6067 T8790 T8791 prep For,cause
R6068 T8792 T8790 pobj example,For
R6069 T8793 T8791 punct ", ",cause
R6070 T8794 T8791 nsubj mutations,cause
R6071 T8795 T8794 prep in,mutations
R6072 T8796 T8795 pobj Tbx22,in
R6073 T8797 T8798 det the,syndrome
R6074 T8798 T8791 dobj syndrome,cause
R6075 T8799 T8798 amod human,syndrome
R6076 T8800 T8801 npadvmod X,linked
R6077 T8801 T8803 amod linked,palate
R6078 T8802 T8801 punct -,linked
R6079 T8803 T8798 appos palate,syndrome
R6080 T8804 T8803 amod cleft,palate
R6081 T8805 T8803 cc and,palate
R6082 T8806 T8803 conj ankyloglossia,palate
R6083 T8807 T8808 punct (,Braybrook
R6084 T8808 T8791 meta Braybrook,cause
R6085 T8809 T8808 nmod et,Braybrook
R6086 T8810 T8808 nmod al.,Braybrook
R6087 T8811 T8808 nummod 2001,Braybrook
R6088 T8812 T8808 punct ),Braybrook
R6089 T8813 T8791 punct .,cause
R6090 T8815 T8816 prep Despite,affect
R6091 T8817 T8818 amod high,levels
R6092 T8818 T8815 pobj levels,Despite
R6093 T8819 T8818 prep of,levels
R6094 T8820 T8821 compound Tbx22,expression
R6095 T8821 T8819 pobj expression,of
R6096 T8822 T8818 prep in,levels
R6097 T8823 T8824 amod periocular,mesenchyme
R6098 T8824 T8822 pobj mesenchyme,in
R6099 T8825 T8824 amod embryonic,mesenchyme
R6100 T8826 T8827 punct (,Braybrook
R6101 T8827 T8818 meta Braybrook,levels
R6102 T8828 T8827 nmod et,Braybrook
R6103 T8829 T8827 nmod al.,Braybrook
R6104 T8830 T8827 nummod 2002,Braybrook
R6105 T8831 T8827 punct ;,Braybrook
R6106 T8832 T8827 nmod Bush,Braybrook
R6107 T8833 T8827 nmod et,Braybrook
R6108 T8834 T8827 nmod al.,Braybrook
R6109 T8835 T8827 nummod 2002,Braybrook
R6110 T8836 T8827 punct ;,Braybrook
R6111 T8837 T8827 nmod Herr,Braybrook
R6112 T8838 T8827 nmod et,Braybrook
R6113 T8839 T8827 nmod al.,Braybrook
R6114 T8840 T8827 nummod 2003,Braybrook
R6115 T8841 T8827 punct ),Braybrook
R6116 T8842 T8816 punct ", ",affect
R6117 T8843 T8844 det the,condition
R6118 T8844 T8816 nsubj condition,affect
R6119 T8845 T8816 aux does,affect
R6120 T8846 T8816 neg not,affect
R6121 T8847 T8848 det the,eye
R6122 T8848 T8816 dobj eye,affect
R6123 T8849 T8816 punct ", ",affect
R6124 T8850 T8851 advmod perhaps,provided
R6125 T8851 T8816 advcl provided,affect
R6126 T8852 T8851 mark because,provided
R6127 T8853 T8854 amod residual,activity
R6128 T8854 T8851 nsubjpass activity,provided
R6129 T8855 T8851 auxpass is,provided
R6130 T8856 T8851 agent by,provided
R6131 T8857 T8856 pobj Tbx15,by
R6132 T8858 T8851 prep in,provided
R6133 T8859 T8860 det the,region
R6134 T8860 T8858 pobj region,in
R6135 T8861 T8860 amod same,region
R6136 T8862 T8816 punct .,affect