Id |
Subject |
Object |
Predicate |
Lexical cue |
T3535 |
0-14 |
NN |
denotes |
Ventralization |
T3536 |
15-17 |
IN |
denotes |
of |
T3537 |
18-22 |
NN |
denotes |
Skin |
T3538 |
23-33 |
NN |
denotes |
Morphology |
T3539 |
34-36 |
IN |
denotes |
by |
T3540 |
37-40 |
DT |
denotes |
the |
T3542 |
41-47 |
JJ |
denotes |
droopy |
T3543 |
48-51 |
NN |
denotes |
ear |
T3541 |
52-60 |
NN |
denotes |
Mutation |
T3544 |
60-391 |
sentence |
denotes |
Named after its effects on craniofacial morphology, droopy ear is a recessive mutation on mouse Chromosome 3; the original allele described more than 40 years ago by Curry (1959) is extinct, but a spontaneous remutation that occurred in Harwell, deH, is available through The Jackson Laboratory (Bar Harbor, Maine, United States). |
T3545 |
61-66 |
VBN |
denotes |
Named |
T3547 |
67-72 |
IN |
denotes |
after |
T3548 |
73-76 |
PRP$ |
denotes |
its |
T3549 |
77-84 |
NNS |
denotes |
effects |
T3550 |
85-87 |
IN |
denotes |
on |
T3551 |
88-100 |
JJ |
denotes |
craniofacial |
T3552 |
101-111 |
NN |
denotes |
morphology |
T3553 |
111-113 |
, |
denotes |
, |
T3554 |
113-119 |
JJ |
denotes |
droopy |
T3555 |
120-123 |
NN |
denotes |
ear |
T3546 |
124-126 |
VBZ |
denotes |
is |
T3557 |
127-128 |
DT |
denotes |
a |
T3559 |
129-138 |
JJ |
denotes |
recessive |
T3558 |
139-147 |
NN |
denotes |
mutation |
T3560 |
148-150 |
IN |
denotes |
on |
T3561 |
151-156 |
NN |
denotes |
mouse |
T3562 |
157-167 |
NN |
denotes |
Chromosome |
T3563 |
168-169 |
CD |
denotes |
3 |
T3564 |
169-170 |
: |
denotes |
; |
T3565 |
171-174 |
DT |
denotes |
the |
T3567 |
175-183 |
JJ |
denotes |
original |
T3566 |
184-190 |
NN |
denotes |
allele |
T3568 |
191-200 |
VBN |
denotes |
described |
T3569 |
201-205 |
JJR |
denotes |
more |
T3571 |
206-210 |
IN |
denotes |
than |
T3570 |
211-213 |
CD |
denotes |
40 |
T3572 |
214-219 |
NNS |
denotes |
years |
T3573 |
220-223 |
RB |
denotes |
ago |
T3574 |
224-226 |
IN |
denotes |
by |
T3575 |
227-232 |
NNP |
denotes |
Curry |
T3576 |
233-234 |
-LRB- |
denotes |
( |
T3577 |
234-238 |
CD |
denotes |
1959 |
T3578 |
238-239 |
-RRB- |
denotes |
) |
T3556 |
240-242 |
VBZ |
denotes |
is |
T3579 |
243-250 |
JJ |
denotes |
extinct |
T3580 |
250-252 |
, |
denotes |
, |
T3581 |
252-255 |
CC |
denotes |
but |
T3582 |
256-257 |
DT |
denotes |
a |
T3584 |
258-269 |
JJ |
denotes |
spontaneous |
T3583 |
270-280 |
NN |
denotes |
remutation |
T3586 |
281-285 |
WDT |
denotes |
that |
T3587 |
286-294 |
VBD |
denotes |
occurred |
T3588 |
295-297 |
IN |
denotes |
in |
T3589 |
298-305 |
NNP |
denotes |
Harwell |
T3590 |
305-307 |
, |
denotes |
, |
T3591 |
307-310 |
NN |
denotes |
deH |
T3592 |
310-312 |
, |
denotes |
, |
T3585 |
312-314 |
VBZ |
denotes |
is |
T3593 |
315-324 |
JJ |
denotes |
available |
T3594 |
325-332 |
IN |
denotes |
through |
T3595 |
333-336 |
DT |
denotes |
The |
T3597 |
337-344 |
NNP |
denotes |
Jackson |
T3596 |
345-355 |
NNP |
denotes |
Laboratory |
T3598 |
356-357 |
-LRB- |
denotes |
( |
T3600 |
357-360 |
NNP |
denotes |
Bar |
T3599 |
361-367 |
NNP |
denotes |
Harbor |
T3601 |
367-369 |
, |
denotes |
, |
T3602 |
369-374 |
NNP |
denotes |
Maine |
T3603 |
374-376 |
, |
denotes |
, |
T3604 |
376-382 |
NNP |
denotes |
United |
T3605 |
383-389 |
NNP |
denotes |
States |
T3606 |
389-390 |
-RRB- |
denotes |
) |
T3607 |
390-391 |
. |
denotes |
. |
T3608 |
391-688 |
sentence |
denotes |
External craniofacial malformations are the most obvious characteristic of deH/deH animals, including widely spaced eyes, small palpebral fissures, a broad nasal area, and a shortened skull held in an elevated position, which presumably causes or contributes to the abnormal position of the ears. |
T3609 |
392-400 |
JJ |
denotes |
External |
T3611 |
401-413 |
JJ |
denotes |
craniofacial |
T3610 |
414-427 |
NNS |
denotes |
malformations |
T3612 |
428-431 |
VBP |
denotes |
are |
T3613 |
432-435 |
DT |
denotes |
the |
T3615 |
436-440 |
RBS |
denotes |
most |
T3616 |
441-448 |
JJ |
denotes |
obvious |
T3614 |
449-463 |
NN |
denotes |
characteristic |
T3617 |
464-466 |
IN |
denotes |
of |
T3618 |
467-470 |
NN |
denotes |
deH |
T3620 |
470-471 |
HYPH |
denotes |
/ |
T3619 |
471-474 |
NN |
denotes |
deH |
T3621 |
475-482 |
NNS |
denotes |
animals |
T3622 |
482-484 |
, |
denotes |
, |
T3623 |
484-493 |
VBG |
denotes |
including |
T3624 |
494-500 |
RB |
denotes |
widely |
T3625 |
501-507 |
VBN |
denotes |
spaced |
T3626 |
508-512 |
NNS |
denotes |
eyes |
T3627 |
512-514 |
, |
denotes |
, |
T3628 |
514-519 |
JJ |
denotes |
small |
T3630 |
520-529 |
JJ |
denotes |
palpebral |
T3629 |
530-538 |
NNS |
denotes |
fissures |
T3631 |
538-540 |
, |
denotes |
, |
T3632 |
540-541 |
DT |
denotes |
a |
T3634 |
542-547 |
JJ |
denotes |
broad |
T3635 |
548-553 |
JJ |
denotes |
nasal |
T3633 |
554-558 |
NN |
denotes |
area |
T3636 |
558-560 |
, |
denotes |
, |
T3637 |
560-563 |
CC |
denotes |
and |
T3638 |
564-565 |
DT |
denotes |
a |
T3640 |
566-575 |
JJ |
denotes |
shortened |
T3639 |
576-581 |
NN |
denotes |
skull |
T3641 |
582-586 |
VBN |
denotes |
held |
T3642 |
587-589 |
IN |
denotes |
in |
T3643 |
590-592 |
DT |
denotes |
an |
T3645 |
593-601 |
JJ |
denotes |
elevated |
T3644 |
602-610 |
NN |
denotes |
position |
T3646 |
610-612 |
, |
denotes |
, |
T3647 |
612-617 |
WDT |
denotes |
which |
T3649 |
618-628 |
RB |
denotes |
presumably |
T3648 |
629-635 |
VBZ |
denotes |
causes |
T3650 |
636-638 |
CC |
denotes |
or |
T3651 |
639-650 |
VBZ |
denotes |
contributes |
T3652 |
651-653 |
IN |
denotes |
to |
T3653 |
654-657 |
DT |
denotes |
the |
T3655 |
658-666 |
JJ |
denotes |
abnormal |
T3654 |
667-675 |
NN |
denotes |
position |
T3656 |
676-678 |
IN |
denotes |
of |
T3657 |
679-682 |
DT |
denotes |
the |
T3658 |
683-687 |
NNS |
denotes |
ears |
T3659 |
687-688 |
. |
denotes |
. |
T3660 |
688-1042 |
sentence |
denotes |
We became interested in droopy ear because the original allele was described to affect pigment pattern in a way that suggests a possible dorsal to ventral transformation: “On a genetic background (at and AW) which causes the belly hair to be lighter than the back hair, the belly hair comes up farther round the sides of the body and face” (Curry 1959). |
T3661 |
689-691 |
PRP |
denotes |
We |
T3662 |
692-698 |
VBD |
denotes |
became |
T3664 |
699-709 |
JJ |
denotes |
interested |
T3665 |
710-712 |
IN |
denotes |
in |
T3666 |
713-719 |
JJ |
denotes |
droopy |
T3667 |
720-723 |
NN |
denotes |
ear |
T3668 |
724-731 |
IN |
denotes |
because |
T3670 |
732-735 |
DT |
denotes |
the |
T3672 |
736-744 |
JJ |
denotes |
original |
T3671 |
745-751 |
NN |
denotes |
allele |
T3673 |
752-755 |
VBD |
denotes |
was |
T3669 |
756-765 |
VBN |
denotes |
described |
T3674 |
766-768 |
TO |
denotes |
to |
T3675 |
769-775 |
VB |
denotes |
affect |
T3676 |
776-783 |
NN |
denotes |
pigment |
T3677 |
784-791 |
NN |
denotes |
pattern |
T3678 |
792-794 |
IN |
denotes |
in |
T3679 |
795-796 |
DT |
denotes |
a |
T3680 |
797-800 |
NN |
denotes |
way |
T3681 |
801-805 |
WDT |
denotes |
that |
T3682 |
806-814 |
VBZ |
denotes |
suggests |
T3683 |
815-816 |
DT |
denotes |
a |
T3685 |
817-825 |
JJ |
denotes |
possible |
T3686 |
826-832 |
JJ |
denotes |
dorsal |
T3687 |
833-835 |
IN |
denotes |
to |
T3688 |
836-843 |
JJ |
denotes |
ventral |
T3684 |
844-858 |
NN |
denotes |
transformation |
T3689 |
858-860 |
: |
denotes |
: |
T3690 |
860-861 |
`` |
denotes |
“ |
T3691 |
861-863 |
IN |
denotes |
On |
T3692 |
864-865 |
DT |
denotes |
a |
T3694 |
866-873 |
JJ |
denotes |
genetic |
T3693 |
874-884 |
NN |
denotes |
background |
T3695 |
885-886 |
-LRB- |
denotes |
( |
T3696 |
886-888 |
NN |
denotes |
at |
T3697 |
889-892 |
CC |
denotes |
and |
T3698 |
893-895 |
NN |
denotes |
AW |
T3699 |
895-896 |
-RRB- |
denotes |
) |
T3700 |
897-902 |
WDT |
denotes |
which |
T3701 |
903-909 |
VBZ |
denotes |
causes |
T3702 |
910-913 |
DT |
denotes |
the |
T3704 |
914-919 |
NN |
denotes |
belly |
T3703 |
920-924 |
NN |
denotes |
hair |
T3706 |
925-927 |
TO |
denotes |
to |
T3705 |
928-930 |
VB |
denotes |
be |
T3707 |
931-938 |
JJR |
denotes |
lighter |
T3708 |
939-943 |
IN |
denotes |
than |
T3709 |
944-947 |
DT |
denotes |
the |
T3711 |
948-952 |
NN |
denotes |
back |
T3710 |
953-957 |
NN |
denotes |
hair |
T3712 |
957-959 |
, |
denotes |
, |
T3713 |
959-962 |
DT |
denotes |
the |
T3715 |
963-968 |
NN |
denotes |
belly |
T3714 |
969-973 |
NN |
denotes |
hair |
T3663 |
974-979 |
VBZ |
denotes |
comes |
T3716 |
980-982 |
RP |
denotes |
up |
T3717 |
983-990 |
RBR |
denotes |
farther |
T3718 |
991-996 |
IN |
denotes |
round |
T3719 |
997-1000 |
DT |
denotes |
the |
T3720 |
1001-1006 |
NNS |
denotes |
sides |
T3721 |
1007-1009 |
IN |
denotes |
of |
T3722 |
1010-1013 |
DT |
denotes |
the |
T3723 |
1014-1018 |
NN |
denotes |
body |
T3724 |
1019-1022 |
CC |
denotes |
and |
T3725 |
1023-1027 |
NN |
denotes |
face |
T3726 |
1027-1028 |
'' |
denotes |
” |
T3727 |
1029-1030 |
-LRB- |
denotes |
( |
T3728 |
1030-1035 |
NNP |
denotes |
Curry |
T3729 |
1036-1040 |
CD |
denotes |
1959 |
T3730 |
1040-1041 |
-RRB- |
denotes |
) |
T3731 |
1041-1042 |
. |
denotes |
. |
T3732 |
1042-1262 |
sentence |
denotes |
An abnormal dorsoventral pigment pattern is readily apparent in at/at; deH/deH mice, but comparison to nonmutant animals is more accurately described in terms of ventral, lateral, and dorsal regions (Figures 1G and 2A). |
T3733 |
1043-1045 |
DT |
denotes |
An |
T3735 |
1046-1054 |
JJ |
denotes |
abnormal |
T3736 |
1055-1067 |
JJ |
denotes |
dorsoventral |
T3737 |
1068-1075 |
NN |
denotes |
pigment |
T3734 |
1076-1083 |
NN |
denotes |
pattern |
T3738 |
1084-1086 |
VBZ |
denotes |
is |
T3739 |
1087-1094 |
RB |
denotes |
readily |
T3740 |
1095-1103 |
JJ |
denotes |
apparent |
T3741 |
1104-1106 |
IN |
denotes |
in |
T3742 |
1107-1109 |
NN |
denotes |
at |
T3744 |
1109-1110 |
HYPH |
denotes |
/ |
T3743 |
1110-1112 |
NN |
denotes |
at |
T3746 |
1112-1113 |
, |
denotes |
; |
T3747 |
1114-1117 |
NN |
denotes |
deH |
T3749 |
1117-1118 |
HYPH |
denotes |
/ |
T3748 |
1118-1121 |
NN |
denotes |
deH |
T3745 |
1122-1126 |
NNS |
denotes |
mice |
T3750 |
1126-1128 |
, |
denotes |
, |
T3751 |
1128-1131 |
CC |
denotes |
but |
T3752 |
1132-1142 |
NN |
denotes |
comparison |
T3754 |
1143-1145 |
IN |
denotes |
to |
T3755 |
1146-1155 |
JJ |
denotes |
nonmutant |
T3756 |
1156-1163 |
NNS |
denotes |
animals |
T3757 |
1164-1166 |
VBZ |
denotes |
is |
T3758 |
1167-1171 |
RBR |
denotes |
more |
T3759 |
1172-1182 |
RB |
denotes |
accurately |
T3753 |
1183-1192 |
VBN |
denotes |
described |
T3760 |
1193-1195 |
IN |
denotes |
in |
T3761 |
1196-1201 |
NNS |
denotes |
terms |
T3762 |
1202-1204 |
IN |
denotes |
of |
T3763 |
1205-1212 |
JJ |
denotes |
ventral |
T3765 |
1212-1214 |
, |
denotes |
, |
T3766 |
1214-1221 |
JJ |
denotes |
lateral |
T3767 |
1221-1223 |
, |
denotes |
, |
T3768 |
1223-1226 |
CC |
denotes |
and |
T3769 |
1227-1233 |
JJ |
denotes |
dorsal |
T3764 |
1234-1241 |
NNS |
denotes |
regions |
T3770 |
1242-1243 |
-LRB- |
denotes |
( |
T3772 |
1243-1250 |
NNS |
denotes |
Figures |
T3771 |
1251-1253 |
CD |
denotes |
1G |
T3773 |
1254-1257 |
CC |
denotes |
and |
T3774 |
1258-1260 |
CD |
denotes |
2A |
T3775 |
1260-1261 |
-RRB- |
denotes |
) |
T3776 |
1261-1262 |
. |
denotes |
. |
T3777 |
1262-1527 |
sentence |
denotes |
The ventral region has short hairs with a gray base and cream-colored tip whose boundary coincides with the limb–body wall junction; both the appearance of this region and position of the boundary are approximately similar in at/at compared to at/at; deH/deH mice. |
T3778 |
1263-1266 |
DT |
denotes |
The |
T3780 |
1267-1274 |
JJ |
denotes |
ventral |
T3779 |
1275-1281 |
NN |
denotes |
region |
T3781 |
1282-1285 |
VBZ |
denotes |
has |
T3783 |
1286-1291 |
JJ |
denotes |
short |
T3784 |
1292-1297 |
NNS |
denotes |
hairs |
T3785 |
1298-1302 |
IN |
denotes |
with |
T3786 |
1303-1304 |
DT |
denotes |
a |
T3788 |
1305-1309 |
JJ |
denotes |
gray |
T3787 |
1310-1314 |
NN |
denotes |
base |
T3789 |
1315-1318 |
CC |
denotes |
and |
T3790 |
1319-1324 |
NN |
denotes |
cream |
T3792 |
1324-1325 |
HYPH |
denotes |
- |
T3791 |
1325-1332 |
VBN |
denotes |
colored |
T3793 |
1333-1336 |
NN |
denotes |
tip |
T3794 |
1337-1342 |
WP$ |
denotes |
whose |
T3795 |
1343-1351 |
NN |
denotes |
boundary |
T3796 |
1352-1361 |
VBZ |
denotes |
coincides |
T3797 |
1362-1366 |
IN |
denotes |
with |
T3798 |
1367-1370 |
DT |
denotes |
the |
T3800 |
1371-1375 |
NN |
denotes |
limb |
T3802 |
1375-1376 |
HYPH |
denotes |
– |
T3801 |
1376-1380 |
NN |
denotes |
body |
T3803 |
1381-1385 |
NN |
denotes |
wall |
T3799 |
1386-1394 |
NN |
denotes |
junction |
T3804 |
1394-1395 |
: |
denotes |
; |
T3805 |
1396-1400 |
CC |
denotes |
both |
T3807 |
1401-1404 |
DT |
denotes |
the |
T3806 |
1405-1415 |
NN |
denotes |
appearance |
T3808 |
1416-1418 |
IN |
denotes |
of |
T3809 |
1419-1423 |
DT |
denotes |
this |
T3810 |
1424-1430 |
NN |
denotes |
region |
T3811 |
1431-1434 |
CC |
denotes |
and |
T3812 |
1435-1443 |
NN |
denotes |
position |
T3813 |
1444-1446 |
IN |
denotes |
of |
T3814 |
1447-1450 |
DT |
denotes |
the |
T3815 |
1451-1459 |
NN |
denotes |
boundary |
T3782 |
1460-1463 |
VBP |
denotes |
are |
T3816 |
1464-1477 |
RB |
denotes |
approximately |
T3817 |
1478-1485 |
JJ |
denotes |
similar |
T3818 |
1486-1488 |
IN |
denotes |
in |
T3819 |
1489-1491 |
NN |
denotes |
at |
T3821 |
1491-1492 |
HYPH |
denotes |
/ |
T3820 |
1492-1494 |
NN |
denotes |
at |
T3823 |
1495-1503 |
VBN |
denotes |
compared |
T3824 |
1504-1506 |
IN |
denotes |
to |
T3825 |
1507-1509 |
NN |
denotes |
at |
T3827 |
1509-1510 |
HYPH |
denotes |
/ |
T3826 |
1510-1512 |
NN |
denotes |
at |
T3828 |
1512-1513 |
, |
denotes |
; |
T3829 |
1514-1517 |
NN |
denotes |
deH |
T3831 |
1517-1518 |
HYPH |
denotes |
/ |
T3830 |
1518-1521 |
NN |
denotes |
deH |
T3822 |
1522-1526 |
NNS |
denotes |
mice |
T3832 |
1526-1527 |
. |
denotes |
. |
T3833 |
1527-1895 |
sentence |
denotes |
The lateral region contains yellow hairs of progressively increasing length; in at/at mice, the lateral region appears as a thin yellow stripe along the flank, but in at/at; deH/deH mice, the lateral region is considerably expanded with a diffuse boundary along the dorsal flank, and a dorsal eumelanic region whose size is correspondingly reduced (Figure 2A and 2B). |
T3834 |
1528-1531 |
DT |
denotes |
The |
T3836 |
1532-1539 |
JJ |
denotes |
lateral |
T3835 |
1540-1546 |
NN |
denotes |
region |
T3837 |
1547-1555 |
VBZ |
denotes |
contains |
T3839 |
1556-1562 |
JJ |
denotes |
yellow |
T3840 |
1563-1568 |
NNS |
denotes |
hairs |
T3841 |
1569-1571 |
IN |
denotes |
of |
T3842 |
1572-1585 |
RB |
denotes |
progressively |
T3843 |
1586-1596 |
VBG |
denotes |
increasing |
T3844 |
1597-1603 |
NN |
denotes |
length |
T3845 |
1603-1604 |
: |
denotes |
; |
T3846 |
1605-1607 |
IN |
denotes |
in |
T3847 |
1608-1610 |
NN |
denotes |
at |
T3849 |
1610-1611 |
HYPH |
denotes |
/ |
T3848 |
1611-1613 |
NN |
denotes |
at |
T3850 |
1614-1618 |
NNS |
denotes |
mice |
T3851 |
1618-1620 |
, |
denotes |
, |
T3852 |
1620-1623 |
DT |
denotes |
the |
T3854 |
1624-1631 |
JJ |
denotes |
lateral |
T3853 |
1632-1638 |
NN |
denotes |
region |
T3838 |
1639-1646 |
VBZ |
denotes |
appears |
T3855 |
1647-1649 |
IN |
denotes |
as |
T3856 |
1650-1651 |
DT |
denotes |
a |
T3858 |
1652-1656 |
JJ |
denotes |
thin |
T3859 |
1657-1663 |
JJ |
denotes |
yellow |
T3857 |
1664-1670 |
NN |
denotes |
stripe |
T3860 |
1671-1676 |
IN |
denotes |
along |
T3861 |
1677-1680 |
DT |
denotes |
the |
T3862 |
1681-1686 |
NN |
denotes |
flank |
T3863 |
1686-1688 |
, |
denotes |
, |
T3864 |
1688-1691 |
CC |
denotes |
but |
T3865 |
1692-1694 |
IN |
denotes |
in |
T3867 |
1695-1697 |
NN |
denotes |
at |
T3869 |
1697-1698 |
HYPH |
denotes |
/ |
T3868 |
1698-1700 |
NN |
denotes |
at |
T3871 |
1700-1701 |
, |
denotes |
; |
T3872 |
1702-1705 |
NN |
denotes |
deH |
T3874 |
1705-1706 |
HYPH |
denotes |
/ |
T3873 |
1706-1709 |
NN |
denotes |
deH |
T3870 |
1710-1714 |
NNS |
denotes |
mice |
T3875 |
1714-1716 |
, |
denotes |
, |
T3876 |
1716-1719 |
DT |
denotes |
the |
T3878 |
1720-1727 |
JJ |
denotes |
lateral |
T3877 |
1728-1734 |
NN |
denotes |
region |
T3866 |
1735-1737 |
VBZ |
denotes |
is |
T3879 |
1738-1750 |
RB |
denotes |
considerably |
T3880 |
1751-1759 |
JJ |
denotes |
expanded |
T3881 |
1760-1764 |
IN |
denotes |
with |
T3882 |
1765-1766 |
DT |
denotes |
a |
T3884 |
1767-1774 |
JJ |
denotes |
diffuse |
T3883 |
1775-1783 |
NN |
denotes |
boundary |
T3885 |
1784-1789 |
IN |
denotes |
along |
T3886 |
1790-1793 |
DT |
denotes |
the |
T3888 |
1794-1800 |
JJ |
denotes |
dorsal |
T3887 |
1801-1806 |
NN |
denotes |
flank |
T3889 |
1806-1808 |
, |
denotes |
, |
T3890 |
1808-1811 |
CC |
denotes |
and |
T3891 |
1812-1813 |
DT |
denotes |
a |
T3893 |
1814-1820 |
JJ |
denotes |
dorsal |
T3894 |
1821-1830 |
JJ |
denotes |
eumelanic |
T3892 |
1831-1837 |
NN |
denotes |
region |
T3895 |
1838-1843 |
WP$ |
denotes |
whose |
T3896 |
1844-1848 |
NN |
denotes |
size |
T3898 |
1849-1851 |
VBZ |
denotes |
is |
T3899 |
1852-1867 |
RB |
denotes |
correspondingly |
T3897 |
1868-1875 |
VBN |
denotes |
reduced |
T3900 |
1876-1877 |
-LRB- |
denotes |
( |
T3902 |
1877-1883 |
NN |
denotes |
Figure |
T3901 |
1884-1886 |
CD |
denotes |
2A |
T3903 |
1887-1890 |
CC |
denotes |
and |
T3904 |
1891-1893 |
CD |
denotes |
2B |
T3905 |
1893-1894 |
-RRB- |
denotes |
) |
T3906 |
1894-1895 |
. |
denotes |
. |
T3907 |
1895-2113 |
sentence |
denotes |
Total body size is smaller in mutant compared to nonmutant animals, but the proportion of body circumference occupied by the lateral region in mutant animals is increased about 2-fold, from 11.9% to 22.2% (Figure 2C). |
T3908 |
1896-1901 |
JJ |
denotes |
Total |
T3910 |
1902-1906 |
NN |
denotes |
body |
T3909 |
1907-1911 |
NN |
denotes |
size |
T3911 |
1912-1914 |
VBZ |
denotes |
is |
T3912 |
1915-1922 |
JJR |
denotes |
smaller |
T3913 |
1923-1925 |
IN |
denotes |
in |
T3914 |
1926-1932 |
JJ |
denotes |
mutant |
T3915 |
1933-1941 |
VBN |
denotes |
compared |
T3916 |
1942-1944 |
IN |
denotes |
to |
T3917 |
1945-1954 |
JJ |
denotes |
nonmutant |
T3918 |
1955-1962 |
NNS |
denotes |
animals |
T3919 |
1962-1964 |
, |
denotes |
, |
T3920 |
1964-1967 |
CC |
denotes |
but |
T3921 |
1968-1971 |
DT |
denotes |
the |
T3922 |
1972-1982 |
NN |
denotes |
proportion |
T3924 |
1983-1985 |
IN |
denotes |
of |
T3925 |
1986-1990 |
NN |
denotes |
body |
T3926 |
1991-2004 |
NN |
denotes |
circumference |
T3927 |
2005-2013 |
VBN |
denotes |
occupied |
T3928 |
2014-2016 |
IN |
denotes |
by |
T3929 |
2017-2020 |
DT |
denotes |
the |
T3931 |
2021-2028 |
JJ |
denotes |
lateral |
T3930 |
2029-2035 |
NN |
denotes |
region |
T3932 |
2036-2038 |
IN |
denotes |
in |
T3933 |
2039-2045 |
JJ |
denotes |
mutant |
T3934 |
2046-2053 |
NNS |
denotes |
animals |
T3935 |
2054-2056 |
VBZ |
denotes |
is |
T3923 |
2057-2066 |
VBN |
denotes |
increased |
T3936 |
2067-2072 |
RB |
denotes |
about |
T3937 |
2073-2074 |
CD |
denotes |
2 |
T3939 |
2074-2075 |
HYPH |
denotes |
- |
T3938 |
2075-2079 |
RB |
denotes |
fold |
T3940 |
2079-2081 |
, |
denotes |
, |
T3941 |
2081-2085 |
IN |
denotes |
from |
T3942 |
2086-2090 |
CD |
denotes |
11.9 |
T3943 |
2090-2091 |
NN |
denotes |
% |
T3944 |
2092-2094 |
IN |
denotes |
to |
T3945 |
2095-2099 |
CD |
denotes |
22.2 |
T3946 |
2099-2100 |
NN |
denotes |
% |
T3947 |
2101-2102 |
-LRB- |
denotes |
( |
T3948 |
2102-2108 |
NN |
denotes |
Figure |
T3949 |
2109-2111 |
CD |
denotes |
2C |
T3950 |
2111-2112 |
-RRB- |
denotes |
) |
T3951 |
2112-2113 |
. |
denotes |
. |
T3952 |
2113-2472 |
sentence |
denotes |
The proportion of the ventral cream-colored region is also expanded a small amount, 47.9% in mutant compared to 37.8% in nonmutant animals, but expansion of the lateral region, which occurs at all levels of the body, including the limbs and the cranium (but not the whisker pad), is the major feature responsible for the ventralized appearance caused by deH. |
T3953 |
2114-2117 |
DT |
denotes |
The |
T3954 |
2118-2128 |
NN |
denotes |
proportion |
T3956 |
2129-2131 |
IN |
denotes |
of |
T3957 |
2132-2135 |
DT |
denotes |
the |
T3959 |
2136-2143 |
JJ |
denotes |
ventral |
T3960 |
2144-2149 |
NN |
denotes |
cream |
T3962 |
2149-2150 |
HYPH |
denotes |
- |
T3961 |
2150-2157 |
VBN |
denotes |
colored |
T3958 |
2158-2164 |
NN |
denotes |
region |
T3963 |
2165-2167 |
VBZ |
denotes |
is |
T3964 |
2168-2172 |
RB |
denotes |
also |
T3955 |
2173-2181 |
VBN |
denotes |
expanded |
T3965 |
2182-2183 |
DT |
denotes |
a |
T3967 |
2184-2189 |
JJ |
denotes |
small |
T3966 |
2190-2196 |
NN |
denotes |
amount |
T3968 |
2196-2198 |
, |
denotes |
, |
T3969 |
2198-2202 |
CD |
denotes |
47.9 |
T3970 |
2202-2203 |
NN |
denotes |
% |
T3971 |
2204-2206 |
IN |
denotes |
in |
T3972 |
2207-2213 |
JJ |
denotes |
mutant |
T3973 |
2214-2222 |
VBN |
denotes |
compared |
T3974 |
2223-2225 |
IN |
denotes |
to |
T3975 |
2226-2230 |
CD |
denotes |
37.8 |
T3976 |
2230-2231 |
NN |
denotes |
% |
T3977 |
2232-2234 |
IN |
denotes |
in |
T3978 |
2235-2244 |
JJ |
denotes |
nonmutant |
T3979 |
2245-2252 |
NNS |
denotes |
animals |
T3980 |
2252-2254 |
, |
denotes |
, |
T3981 |
2254-2257 |
CC |
denotes |
but |
T3982 |
2258-2267 |
NN |
denotes |
expansion |
T3984 |
2268-2270 |
IN |
denotes |
of |
T3985 |
2271-2274 |
DT |
denotes |
the |
T3987 |
2275-2282 |
JJ |
denotes |
lateral |
T3986 |
2283-2289 |
NN |
denotes |
region |
T3988 |
2289-2291 |
, |
denotes |
, |
T3989 |
2291-2296 |
WDT |
denotes |
which |
T3990 |
2297-2303 |
VBZ |
denotes |
occurs |
T3991 |
2304-2306 |
IN |
denotes |
at |
T3992 |
2307-2310 |
DT |
denotes |
all |
T3993 |
2311-2317 |
NNS |
denotes |
levels |
T3994 |
2318-2320 |
IN |
denotes |
of |
T3995 |
2321-2324 |
DT |
denotes |
the |
T3996 |
2325-2329 |
NN |
denotes |
body |
T3997 |
2329-2331 |
, |
denotes |
, |
T3998 |
2331-2340 |
VBG |
denotes |
including |
T3999 |
2341-2344 |
DT |
denotes |
the |
T4000 |
2345-2350 |
NNS |
denotes |
limbs |
T4001 |
2351-2354 |
CC |
denotes |
and |
T4002 |
2355-2358 |
DT |
denotes |
the |
T4003 |
2359-2366 |
NN |
denotes |
cranium |
T4004 |
2367-2368 |
-LRB- |
denotes |
( |
T4005 |
2368-2371 |
CC |
denotes |
but |
T4006 |
2372-2375 |
RB |
denotes |
not |
T4007 |
2376-2379 |
DT |
denotes |
the |
T4009 |
2380-2387 |
NN |
denotes |
whisker |
T4008 |
2388-2391 |
NN |
denotes |
pad |
T4010 |
2391-2392 |
-RRB- |
denotes |
) |
T4011 |
2392-2394 |
, |
denotes |
, |
T3983 |
2394-2396 |
VBZ |
denotes |
is |
T4012 |
2397-2400 |
DT |
denotes |
the |
T4014 |
2401-2406 |
JJ |
denotes |
major |
T4013 |
2407-2414 |
NN |
denotes |
feature |
T4015 |
2415-2426 |
JJ |
denotes |
responsible |
T4016 |
2427-2430 |
IN |
denotes |
for |
T4017 |
2431-2434 |
DT |
denotes |
the |
T4019 |
2435-2446 |
VBN |
denotes |
ventralized |
T4018 |
2447-2457 |
NN |
denotes |
appearance |
T4020 |
2458-2464 |
VBN |
denotes |
caused |
T4021 |
2465-2467 |
IN |
denotes |
by |
T4022 |
2468-2471 |
NN |
denotes |
deH |
T4023 |
2471-2472 |
. |
denotes |
. |
T4024 |
2472-3937 |
sentence |
denotes |
Figure 2 The deH Pigmentation Phenotype
(A) 10-wk-old deH/deH and nonmutant animals on a at background. A thin stripe of yellow hair normally separates the dorsal black hairs from the ventral cream hairs. In deH, the yellow stripe is extended dorsally, and the boundary between the yellow and the black hairs is fuzzier.
(B) Skin slices taken from 1.5-mo-old deH/deH and nonmutant littermates (scale bar = 0.5 cm).
(C) Proportion of total skin area as determined by observation of pelts taken from the interlimb region. The proportion occupied by the yellow lateral compartment (± SEM) differs between mutant and nonmutant littermate flanks (p < 0.0005, paired t-test, n = 6 pairs). There is also (data not shown) a small increase in the proportion of total skin area occupied by the ventral cream-colored compartment, 47.9 % in mutant compared to 37.8% in nonmutant (p < 0.005, paired t-test, n = 6 pairs).
(D) On an ae/ae background, the extent of dorsal skin pigmentation is reduced in deH/deH neonates (P3.5).
(E) Hair length in a representative pair of 1.5-mo-old deH/deH and nonmutant littermates, averaged over three skin slices at different rostrocaudal levels, and plotted as a function of the absolute distance from middorsum or the percentage of total slice length. To investigate whether deH affects other dorsoventral skin characteristics besides pigment-type switching, we examined its effects on hair length and pigmentation in an ae/ae background. |
T4025 |
3751-3753 |
TO |
denotes |
To |
T4026 |
3754-3765 |
VB |
denotes |
investigate |
T4028 |
3766-3773 |
IN |
denotes |
whether |
T4030 |
3774-3777 |
NN |
denotes |
deH |
T4029 |
3778-3785 |
VBZ |
denotes |
affects |
T4031 |
3786-3791 |
JJ |
denotes |
other |
T4033 |
3792-3804 |
JJ |
denotes |
dorsoventral |
T4034 |
3805-3809 |
NN |
denotes |
skin |
T4032 |
3810-3825 |
NNS |
denotes |
characteristics |
T4035 |
3826-3833 |
IN |
denotes |
besides |
T4036 |
3834-3841 |
NN |
denotes |
pigment |
T4038 |
3841-3842 |
HYPH |
denotes |
- |
T4037 |
3842-3846 |
NN |
denotes |
type |
T4039 |
3847-3856 |
VBG |
denotes |
switching |
T4040 |
3856-3858 |
, |
denotes |
, |
T4041 |
3858-3860 |
PRP |
denotes |
we |
T4027 |
3861-3869 |
VBD |
denotes |
examined |
T4042 |
3870-3873 |
PRP$ |
denotes |
its |
T4043 |
3874-3881 |
NNS |
denotes |
effects |
T4044 |
3882-3884 |
IN |
denotes |
on |
T4045 |
3885-3889 |
NN |
denotes |
hair |
T4046 |
3890-3896 |
NN |
denotes |
length |
T4047 |
3897-3900 |
CC |
denotes |
and |
T4048 |
3901-3913 |
NN |
denotes |
pigmentation |
T4049 |
3914-3916 |
IN |
denotes |
in |
T4050 |
3917-3919 |
DT |
denotes |
an |
T4052 |
3920-3922 |
NN |
denotes |
ae |
T4054 |
3922-3923 |
HYPH |
denotes |
/ |
T4053 |
3923-3925 |
NN |
denotes |
ae |
T4051 |
3926-3936 |
NN |
denotes |
background |
T4055 |
3936-3937 |
. |
denotes |
. |
T4056 |
3937-4178 |
sentence |
denotes |
Overall, deH causes a small but consistent reduction in hair length in both dorsum and ventrum; when mutant and nonmutant animals are normalized for body circumference, reduced hair length is most apparent in the lateral region (Figure 2E). |
T4057 |
3938-3945 |
RB |
denotes |
Overall |
T4059 |
3945-3947 |
, |
denotes |
, |
T4060 |
3947-3950 |
NN |
denotes |
deH |
T4058 |
3951-3957 |
VBZ |
denotes |
causes |
T4062 |
3958-3959 |
DT |
denotes |
a |
T4064 |
3960-3965 |
JJ |
denotes |
small |
T4065 |
3966-3969 |
CC |
denotes |
but |
T4066 |
3970-3980 |
JJ |
denotes |
consistent |
T4063 |
3981-3990 |
NN |
denotes |
reduction |
T4067 |
3991-3993 |
IN |
denotes |
in |
T4068 |
3994-3998 |
NN |
denotes |
hair |
T4069 |
3999-4005 |
NN |
denotes |
length |
T4070 |
4006-4008 |
IN |
denotes |
in |
T4071 |
4009-4013 |
CC |
denotes |
both |
T4072 |
4014-4020 |
NN |
denotes |
dorsum |
T4073 |
4021-4024 |
CC |
denotes |
and |
T4074 |
4025-4032 |
NN |
denotes |
ventrum |
T4075 |
4032-4033 |
: |
denotes |
; |
T4076 |
4034-4038 |
WRB |
denotes |
when |
T4078 |
4039-4045 |
JJ |
denotes |
mutant |
T4080 |
4046-4049 |
CC |
denotes |
and |
T4081 |
4050-4059 |
JJ |
denotes |
nonmutant |
T4079 |
4060-4067 |
NNS |
denotes |
animals |
T4082 |
4068-4071 |
VBP |
denotes |
are |
T4077 |
4072-4082 |
VBN |
denotes |
normalized |
T4083 |
4083-4086 |
IN |
denotes |
for |
T4084 |
4087-4091 |
NN |
denotes |
body |
T4085 |
4092-4105 |
NN |
denotes |
circumference |
T4086 |
4105-4107 |
, |
denotes |
, |
T4087 |
4107-4114 |
JJ |
denotes |
reduced |
T4089 |
4115-4119 |
NN |
denotes |
hair |
T4088 |
4120-4126 |
NN |
denotes |
length |
T4061 |
4127-4129 |
VBZ |
denotes |
is |
T4090 |
4130-4134 |
RBS |
denotes |
most |
T4091 |
4135-4143 |
JJ |
denotes |
apparent |
T4092 |
4144-4146 |
IN |
denotes |
in |
T4093 |
4147-4150 |
DT |
denotes |
the |
T4095 |
4151-4158 |
JJ |
denotes |
lateral |
T4094 |
4159-4165 |
NN |
denotes |
region |
T4096 |
4166-4167 |
-LRB- |
denotes |
( |
T4097 |
4167-4173 |
NN |
denotes |
Figure |
T4098 |
4174-4176 |
CD |
denotes |
2E |
T4099 |
4176-4177 |
-RRB- |
denotes |
) |
T4100 |
4177-4178 |
. |
denotes |
. |
T4101 |
4178-4317 |
sentence |
denotes |
Adult ae/ae; deH/deH animals exhibit body-size reduction and skeletal abnormalities, but display no coat-color phenotype (data not shown). |
T4102 |
4179-4184 |
JJ |
denotes |
Adult |
T4104 |
4185-4187 |
NN |
denotes |
ae |
T4106 |
4187-4188 |
HYPH |
denotes |
/ |
T4105 |
4188-4190 |
NN |
denotes |
ae |
T4107 |
4190-4191 |
, |
denotes |
; |
T4108 |
4192-4195 |
NN |
denotes |
deH |
T4110 |
4195-4196 |
HYPH |
denotes |
/ |
T4109 |
4196-4199 |
NN |
denotes |
deH |
T4103 |
4200-4207 |
NNS |
denotes |
animals |
T4111 |
4208-4215 |
VBP |
denotes |
exhibit |
T4112 |
4216-4220 |
NN |
denotes |
body |
T4114 |
4220-4221 |
HYPH |
denotes |
- |
T4113 |
4221-4225 |
NN |
denotes |
size |
T4115 |
4226-4235 |
NN |
denotes |
reduction |
T4116 |
4236-4239 |
CC |
denotes |
and |
T4117 |
4240-4248 |
JJ |
denotes |
skeletal |
T4118 |
4249-4262 |
NNS |
denotes |
abnormalities |
T4119 |
4262-4264 |
, |
denotes |
, |
T4120 |
4264-4267 |
CC |
denotes |
but |
T4121 |
4268-4275 |
VBP |
denotes |
display |
T4122 |
4276-4278 |
DT |
denotes |
no |
T4124 |
4279-4283 |
NN |
denotes |
coat |
T4126 |
4283-4284 |
HYPH |
denotes |
- |
T4125 |
4284-4289 |
NN |
denotes |
color |
T4123 |
4290-4299 |
NN |
denotes |
phenotype |
T4127 |
4300-4301 |
-LRB- |
denotes |
( |
T4129 |
4301-4305 |
NNS |
denotes |
data |
T4130 |
4306-4309 |
RB |
denotes |
not |
T4128 |
4310-4315 |
VBN |
denotes |
shown |
T4131 |
4315-4316 |
-RRB- |
denotes |
) |
T4132 |
4316-4317 |
. |
denotes |
. |
T4133 |
4317-4516 |
sentence |
denotes |
However, ae/ae and ae/ae; deH/deH neonates are clearly distinguishable in the first few days after birth, when a dorsoventral gradient of melanogenic activity is apparent under the skin (Figure 2D). |
T4134 |
4318-4325 |
RB |
denotes |
However |
T4136 |
4325-4327 |
, |
denotes |
, |
T4137 |
4327-4329 |
NN |
denotes |
ae |
T4139 |
4329-4330 |
SYM |
denotes |
/ |
T4138 |
4330-4332 |
NN |
denotes |
ae |
T4141 |
4333-4336 |
CC |
denotes |
and |
T4142 |
4337-4339 |
NN |
denotes |
ae |
T4144 |
4339-4340 |
SYM |
denotes |
/ |
T4143 |
4340-4342 |
NN |
denotes |
ae |
T4145 |
4342-4343 |
, |
denotes |
; |
T4146 |
4344-4347 |
NN |
denotes |
deH |
T4148 |
4347-4348 |
HYPH |
denotes |
/ |
T4147 |
4348-4351 |
NN |
denotes |
deH |
T4140 |
4352-4360 |
NNS |
denotes |
neonates |
T4135 |
4361-4364 |
VBP |
denotes |
are |
T4149 |
4365-4372 |
RB |
denotes |
clearly |
T4150 |
4373-4388 |
JJ |
denotes |
distinguishable |
T4151 |
4389-4391 |
IN |
denotes |
in |
T4152 |
4392-4395 |
DT |
denotes |
the |
T4154 |
4396-4401 |
JJ |
denotes |
first |
T4155 |
4402-4405 |
JJ |
denotes |
few |
T4153 |
4406-4410 |
NNS |
denotes |
days |
T4156 |
4411-4416 |
IN |
denotes |
after |
T4157 |
4417-4422 |
NN |
denotes |
birth |
T4158 |
4422-4424 |
, |
denotes |
, |
T4159 |
4424-4428 |
WRB |
denotes |
when |
T4161 |
4429-4430 |
DT |
denotes |
a |
T4163 |
4431-4443 |
JJ |
denotes |
dorsoventral |
T4162 |
4444-4452 |
NN |
denotes |
gradient |
T4164 |
4453-4455 |
IN |
denotes |
of |
T4165 |
4456-4467 |
JJ |
denotes |
melanogenic |
T4166 |
4468-4476 |
NN |
denotes |
activity |
T4160 |
4477-4479 |
VBZ |
denotes |
is |
T4167 |
4480-4488 |
JJ |
denotes |
apparent |
T4168 |
4489-4494 |
IN |
denotes |
under |
T4169 |
4495-4498 |
DT |
denotes |
the |
T4170 |
4499-4503 |
NN |
denotes |
skin |
T4171 |
4504-4505 |
-LRB- |
denotes |
( |
T4172 |
4505-4511 |
NN |
denotes |
Figure |
T4173 |
4512-4514 |
CD |
denotes |
2D |
T4174 |
4514-4515 |
-RRB- |
denotes |
) |
T4175 |
4515-4516 |
. |
denotes |
. |
T4176 |
4516-4685 |
sentence |
denotes |
At this stage, melanoblast migration from the neural crest is mostly complete, but there is a dorsoventral gradient in melanocyte differentiation and pigment synthesis. |
T4177 |
4517-4519 |
IN |
denotes |
At |
T4179 |
4520-4524 |
DT |
denotes |
this |
T4180 |
4525-4530 |
NN |
denotes |
stage |
T4181 |
4530-4532 |
, |
denotes |
, |
T4182 |
4532-4543 |
NN |
denotes |
melanoblast |
T4183 |
4544-4553 |
NN |
denotes |
migration |
T4184 |
4554-4558 |
IN |
denotes |
from |
T4185 |
4559-4562 |
DT |
denotes |
the |
T4187 |
4563-4569 |
JJ |
denotes |
neural |
T4186 |
4570-4575 |
NN |
denotes |
crest |
T4178 |
4576-4578 |
VBZ |
denotes |
is |
T4188 |
4579-4585 |
RB |
denotes |
mostly |
T4189 |
4586-4594 |
JJ |
denotes |
complete |
T4190 |
4594-4596 |
, |
denotes |
, |
T4191 |
4596-4599 |
CC |
denotes |
but |
T4192 |
4600-4605 |
EX |
denotes |
there |
T4193 |
4606-4608 |
VBZ |
denotes |
is |
T4194 |
4609-4610 |
DT |
denotes |
a |
T4196 |
4611-4623 |
JJ |
denotes |
dorsoventral |
T4195 |
4624-4632 |
NN |
denotes |
gradient |
T4197 |
4633-4635 |
IN |
denotes |
in |
T4198 |
4636-4646 |
NN |
denotes |
melanocyte |
T4199 |
4647-4662 |
NN |
denotes |
differentiation |
T4200 |
4663-4666 |
CC |
denotes |
and |
T4201 |
4667-4674 |
NN |
denotes |
pigment |
T4202 |
4675-4684 |
NN |
denotes |
synthesis |
T4203 |
4684-4685 |
. |
denotes |
. |
T4204 |
4685-4942 |
sentence |
denotes |
The skin of ae/ae neonates appears uniformly dark over the entire dorsum, but in ae/ae; deH/deH neonates, the area of dark skin is more restricted, particularly above the limbs, and resembles the pattern of dorsal eumelanin in at/at; deH/deH adult animals. |
T4205 |
4686-4689 |
DT |
denotes |
The |
T4206 |
4690-4694 |
NN |
denotes |
skin |
T4208 |
4695-4697 |
IN |
denotes |
of |
T4209 |
4698-4700 |
NN |
denotes |
ae |
T4211 |
4700-4701 |
HYPH |
denotes |
/ |
T4210 |
4701-4703 |
NN |
denotes |
ae |
T4212 |
4704-4712 |
NNS |
denotes |
neonates |
T4207 |
4713-4720 |
VBZ |
denotes |
appears |
T4213 |
4721-4730 |
RB |
denotes |
uniformly |
T4214 |
4731-4735 |
JJ |
denotes |
dark |
T4215 |
4736-4740 |
IN |
denotes |
over |
T4216 |
4741-4744 |
DT |
denotes |
the |
T4218 |
4745-4751 |
JJ |
denotes |
entire |
T4217 |
4752-4758 |
NN |
denotes |
dorsum |
T4219 |
4758-4760 |
, |
denotes |
, |
T4220 |
4760-4763 |
CC |
denotes |
but |
T4221 |
4764-4766 |
IN |
denotes |
in |
T4223 |
4767-4769 |
NN |
denotes |
ae |
T4225 |
4769-4770 |
HYPH |
denotes |
/ |
T4224 |
4770-4772 |
NN |
denotes |
ae |
T4227 |
4772-4773 |
: |
denotes |
; |
T4228 |
4774-4777 |
NN |
denotes |
deH |
T4230 |
4777-4778 |
HYPH |
denotes |
/ |
T4229 |
4778-4781 |
NN |
denotes |
deH |
T4226 |
4782-4790 |
NNS |
denotes |
neonates |
T4231 |
4790-4792 |
, |
denotes |
, |
T4232 |
4792-4795 |
DT |
denotes |
the |
T4233 |
4796-4800 |
NN |
denotes |
area |
T4234 |
4801-4803 |
IN |
denotes |
of |
T4235 |
4804-4808 |
JJ |
denotes |
dark |
T4236 |
4809-4813 |
NN |
denotes |
skin |
T4222 |
4814-4816 |
VBZ |
denotes |
is |
T4237 |
4817-4821 |
RBR |
denotes |
more |
T4238 |
4822-4832 |
JJ |
denotes |
restricted |
T4239 |
4832-4834 |
, |
denotes |
, |
T4240 |
4834-4846 |
RB |
denotes |
particularly |
T4241 |
4847-4852 |
IN |
denotes |
above |
T4242 |
4853-4856 |
DT |
denotes |
the |
T4243 |
4857-4862 |
NNS |
denotes |
limbs |
T4244 |
4862-4864 |
, |
denotes |
, |
T4245 |
4864-4867 |
CC |
denotes |
and |
T4246 |
4868-4877 |
VBZ |
denotes |
resembles |
T4247 |
4878-4881 |
DT |
denotes |
the |
T4248 |
4882-4889 |
NN |
denotes |
pattern |
T4249 |
4890-4892 |
IN |
denotes |
of |
T4250 |
4893-4899 |
JJ |
denotes |
dorsal |
T4251 |
4900-4909 |
NN |
denotes |
eumelanin |
T4252 |
4910-4912 |
IN |
denotes |
in |
T4253 |
4913-4915 |
NN |
denotes |
at |
T4255 |
4915-4916 |
HYPH |
denotes |
/ |
T4254 |
4916-4918 |
NN |
denotes |
at |
T4257 |
4918-4919 |
, |
denotes |
; |
T4258 |
4920-4923 |
NN |
denotes |
deH |
T4260 |
4923-4924 |
HYPH |
denotes |
/ |
T4259 |
4924-4927 |
NN |
denotes |
deH |
T4261 |
4928-4933 |
JJ |
denotes |
adult |
T4256 |
4934-4941 |
NNS |
denotes |
animals |
T4262 |
4941-4942 |
. |
denotes |
. |
T4263 |
4942-5161 |
sentence |
denotes |
Taken together, these observations suggest that deH interferes with the establishment of dorsoventral patterning during skin development by causing dorsal expansion of a lateral region that is normally 3–5 mm in width. |
T4264 |
4943-4948 |
VBN |
denotes |
Taken |
T4266 |
4949-4957 |
RB |
denotes |
together |
T4267 |
4957-4959 |
, |
denotes |
, |
T4268 |
4959-4964 |
DT |
denotes |
these |
T4269 |
4965-4977 |
NNS |
denotes |
observations |
T4265 |
4978-4985 |
VBP |
denotes |
suggest |
T4270 |
4986-4990 |
IN |
denotes |
that |
T4272 |
4991-4994 |
NN |
denotes |
deH |
T4271 |
4995-5005 |
VBZ |
denotes |
interferes |
T4273 |
5006-5010 |
IN |
denotes |
with |
T4274 |
5011-5014 |
DT |
denotes |
the |
T4275 |
5015-5028 |
NN |
denotes |
establishment |
T4276 |
5029-5031 |
IN |
denotes |
of |
T4277 |
5032-5044 |
JJ |
denotes |
dorsoventral |
T4278 |
5045-5055 |
NN |
denotes |
patterning |
T4279 |
5056-5062 |
IN |
denotes |
during |
T4280 |
5063-5067 |
NN |
denotes |
skin |
T4281 |
5068-5079 |
NN |
denotes |
development |
T4282 |
5080-5082 |
IN |
denotes |
by |
T4283 |
5083-5090 |
VBG |
denotes |
causing |
T4284 |
5091-5097 |
JJ |
denotes |
dorsal |
T4285 |
5098-5107 |
NN |
denotes |
expansion |
T4286 |
5108-5110 |
IN |
denotes |
of |
T4287 |
5111-5112 |
DT |
denotes |
a |
T4289 |
5113-5120 |
JJ |
denotes |
lateral |
T4288 |
5121-5127 |
NN |
denotes |
region |
T4290 |
5128-5132 |
WDT |
denotes |
that |
T4291 |
5133-5135 |
VBZ |
denotes |
is |
T4292 |
5136-5144 |
RB |
denotes |
normally |
T4293 |
5145-5146 |
CD |
denotes |
3 |
T4295 |
5146-5147 |
SYM |
denotes |
– |
T4294 |
5147-5148 |
CD |
denotes |
5 |
T4296 |
5149-5151 |
NN |
denotes |
mm |
T4297 |
5152-5154 |
IN |
denotes |
in |
T4298 |
5155-5160 |
NN |
denotes |
width |
T4299 |
5160-5161 |
. |
denotes |
. |
T4300 |
5161-5392 |
sentence |
denotes |
This same region may serve as a boundary between dorsal and ventral skin by inhibiting melanocyte differentiation, by promoting pheomelanin synthesis, and by supporting a progressive increase in hair growth from ventrum to dorsum. |
T4301 |
5162-5166 |
DT |
denotes |
This |
T4303 |
5167-5171 |
JJ |
denotes |
same |
T4302 |
5172-5178 |
NN |
denotes |
region |
T4305 |
5179-5182 |
MD |
denotes |
may |
T4304 |
5183-5188 |
VB |
denotes |
serve |
T4306 |
5189-5191 |
IN |
denotes |
as |
T4307 |
5192-5193 |
DT |
denotes |
a |
T4308 |
5194-5202 |
NN |
denotes |
boundary |
T4309 |
5203-5210 |
IN |
denotes |
between |
T4310 |
5211-5217 |
JJ |
denotes |
dorsal |
T4312 |
5218-5221 |
CC |
denotes |
and |
T4313 |
5222-5229 |
JJ |
denotes |
ventral |
T4311 |
5230-5234 |
NN |
denotes |
skin |
T4314 |
5235-5237 |
IN |
denotes |
by |
T4315 |
5238-5248 |
VBG |
denotes |
inhibiting |
T4316 |
5249-5259 |
NN |
denotes |
melanocyte |
T4317 |
5260-5275 |
NN |
denotes |
differentiation |
T4318 |
5275-5277 |
, |
denotes |
, |
T4319 |
5277-5279 |
IN |
denotes |
by |
T4320 |
5280-5289 |
VBG |
denotes |
promoting |
T4321 |
5290-5301 |
NN |
denotes |
pheomelanin |
T4322 |
5302-5311 |
NN |
denotes |
synthesis |
T4323 |
5311-5313 |
, |
denotes |
, |
T4324 |
5313-5316 |
CC |
denotes |
and |
T4325 |
5317-5319 |
IN |
denotes |
by |
T4326 |
5320-5330 |
VBG |
denotes |
supporting |
T4327 |
5331-5332 |
DT |
denotes |
a |
T4329 |
5333-5344 |
JJ |
denotes |
progressive |
T4328 |
5345-5353 |
NN |
denotes |
increase |
T4330 |
5354-5356 |
IN |
denotes |
in |
T4331 |
5357-5361 |
NN |
denotes |
hair |
T4332 |
5362-5368 |
NN |
denotes |
growth |
T4333 |
5369-5373 |
IN |
denotes |
from |
T4334 |
5374-5381 |
NN |
denotes |
ventrum |
T4335 |
5382-5384 |
IN |
denotes |
to |
T4336 |
5385-5391 |
NN |
denotes |
dorsum |
T4337 |
5391-5392 |
. |
denotes |
. |
T4338 |
5392-5594 |
sentence |
denotes |
As described below, the gene defective in deH, Tbx15, is normally expressed in the dorsal region and therefore is likely to play a role in establishing the size and dorsal extent of the lateral region. |
T4339 |
5393-5395 |
IN |
denotes |
As |
T4340 |
5396-5405 |
VBN |
denotes |
described |
T4342 |
5406-5411 |
RB |
denotes |
below |
T4343 |
5411-5413 |
, |
denotes |
, |
T4344 |
5413-5416 |
DT |
denotes |
the |
T4345 |
5417-5421 |
NN |
denotes |
gene |
T4346 |
5422-5431 |
JJ |
denotes |
defective |
T4347 |
5432-5434 |
IN |
denotes |
in |
T4348 |
5435-5438 |
NN |
denotes |
deH |
T4349 |
5438-5440 |
, |
denotes |
, |
T4350 |
5440-5445 |
NN |
denotes |
Tbx15 |
T4351 |
5445-5447 |
, |
denotes |
, |
T4352 |
5447-5449 |
VBZ |
denotes |
is |
T4353 |
5450-5458 |
RB |
denotes |
normally |
T4341 |
5459-5468 |
VBN |
denotes |
expressed |
T4354 |
5469-5471 |
IN |
denotes |
in |
T4355 |
5472-5475 |
DT |
denotes |
the |
T4357 |
5476-5482 |
JJ |
denotes |
dorsal |
T4356 |
5483-5489 |
NN |
denotes |
region |
T4358 |
5490-5493 |
CC |
denotes |
and |
T4359 |
5494-5503 |
RB |
denotes |
therefore |
T4360 |
5504-5506 |
VBZ |
denotes |
is |
T4361 |
5507-5513 |
JJ |
denotes |
likely |
T4362 |
5514-5516 |
TO |
denotes |
to |
T4363 |
5517-5521 |
VB |
denotes |
play |
T4364 |
5522-5523 |
DT |
denotes |
a |
T4365 |
5524-5528 |
NN |
denotes |
role |
T4366 |
5529-5531 |
IN |
denotes |
in |
T4367 |
5532-5544 |
VBG |
denotes |
establishing |
T4368 |
5545-5548 |
DT |
denotes |
the |
T4369 |
5549-5553 |
NN |
denotes |
size |
T4370 |
5554-5557 |
CC |
denotes |
and |
T4371 |
5558-5564 |
JJ |
denotes |
dorsal |
T4372 |
5565-5571 |
NN |
denotes |
extent |
T4373 |
5572-5574 |
IN |
denotes |
of |
T4374 |
5575-5578 |
DT |
denotes |
the |
T4376 |
5579-5586 |
JJ |
denotes |
lateral |
T4375 |
5587-5593 |
NN |
denotes |
region |
T4377 |
5593-5594 |
. |
denotes |
. |
R2278 |
T3536 |
T3535 |
prep |
of,Ventralization |
R2279 |
T3537 |
T3538 |
compound |
Skin,Morphology |
R2280 |
T3538 |
T3536 |
pobj |
Morphology,of |
R2281 |
T3539 |
T3535 |
prep |
by,Ventralization |
R2282 |
T3540 |
T3541 |
det |
the,Mutation |
R2283 |
T3541 |
T3539 |
pobj |
Mutation,by |
R2284 |
T3542 |
T3543 |
amod |
droopy,ear |
R2285 |
T3543 |
T3541 |
compound |
ear,Mutation |
R2286 |
T3545 |
T3546 |
advcl |
Named,is |
R2287 |
T3546 |
T3556 |
ccomp |
is,is |
R2288 |
T3547 |
T3545 |
prep |
after,Named |
R2289 |
T3548 |
T3549 |
poss |
its,effects |
R2290 |
T3549 |
T3547 |
pobj |
effects,after |
R2291 |
T3550 |
T3549 |
prep |
on,effects |
R2292 |
T3551 |
T3552 |
amod |
craniofacial,morphology |
R2293 |
T3552 |
T3550 |
pobj |
morphology,on |
R2294 |
T3553 |
T3546 |
punct |
", ",is |
R2295 |
T3554 |
T3555 |
amod |
droopy,ear |
R2296 |
T3555 |
T3546 |
nsubj |
ear,is |
R2297 |
T3557 |
T3558 |
det |
a,mutation |
R2298 |
T3558 |
T3546 |
attr |
mutation,is |
R2299 |
T3559 |
T3558 |
amod |
recessive,mutation |
R2300 |
T3560 |
T3558 |
prep |
on,mutation |
R2301 |
T3561 |
T3562 |
compound |
mouse,Chromosome |
R2302 |
T3562 |
T3560 |
pobj |
Chromosome,on |
R2303 |
T3563 |
T3562 |
nummod |
3,Chromosome |
R2304 |
T3564 |
T3556 |
punct |
;,is |
R2305 |
T3565 |
T3566 |
det |
the,allele |
R2306 |
T3566 |
T3556 |
nsubj |
allele,is |
R2307 |
T3567 |
T3566 |
amod |
original,allele |
R2308 |
T3568 |
T3566 |
acl |
described,allele |
R2309 |
T3569 |
T3570 |
amod |
more,40 |
R2310 |
T3570 |
T3572 |
nummod |
40,years |
R2311 |
T3571 |
T3570 |
quantmod |
than,40 |
R2312 |
T3572 |
T3573 |
npadvmod |
years,ago |
R2313 |
T3573 |
T3568 |
advmod |
ago,described |
R2314 |
T3574 |
T3568 |
agent |
by,described |
R2315 |
T3575 |
T3574 |
pobj |
Curry,by |
R2316 |
T3576 |
T3577 |
punct |
(,1959 |
R2317 |
T3577 |
T3568 |
parataxis |
1959,described |
R2318 |
T3578 |
T3577 |
punct |
),1959 |
R2319 |
T3579 |
T3556 |
acomp |
extinct,is |
R2320 |
T3580 |
T3556 |
punct |
", ",is |
R2321 |
T3581 |
T3556 |
cc |
but,is |
R2322 |
T3582 |
T3583 |
det |
a,remutation |
R2323 |
T3583 |
T3585 |
nsubj |
remutation,is |
R2324 |
T3584 |
T3583 |
amod |
spontaneous,remutation |
R2325 |
T3585 |
T3556 |
conj |
is,is |
R2326 |
T3586 |
T3587 |
dep |
that,occurred |
R2327 |
T3587 |
T3583 |
relcl |
occurred,remutation |
R2328 |
T3588 |
T3587 |
prep |
in,occurred |
R2329 |
T3589 |
T3588 |
pobj |
Harwell,in |
R2330 |
T3590 |
T3583 |
punct |
", ",remutation |
R2331 |
T3591 |
T3583 |
appos |
deH,remutation |
R2332 |
T3592 |
T3585 |
punct |
", ",is |
R2333 |
T3593 |
T3585 |
acomp |
available,is |
R2334 |
T3594 |
T3585 |
prep |
through,is |
R2335 |
T3595 |
T3596 |
det |
The,Laboratory |
R2336 |
T3596 |
T3594 |
pobj |
Laboratory,through |
R2337 |
T3597 |
T3596 |
compound |
Jackson,Laboratory |
R2338 |
T3598 |
T3599 |
punct |
(,Harbor |
R2339 |
T3599 |
T3585 |
parataxis |
Harbor,is |
R2340 |
T3600 |
T3599 |
compound |
Bar,Harbor |
R2341 |
T3601 |
T3599 |
punct |
", ",Harbor |
R2342 |
T3602 |
T3599 |
npadvmod |
Maine,Harbor |
R2343 |
T3603 |
T3599 |
punct |
", ",Harbor |
R2344 |
T3604 |
T3605 |
compound |
United,States |
R2345 |
T3605 |
T3599 |
npadvmod |
States,Harbor |
R2346 |
T3606 |
T3599 |
punct |
),Harbor |
R2347 |
T3607 |
T3556 |
punct |
.,is |
R2348 |
T3609 |
T3610 |
amod |
External,malformations |
R2349 |
T3610 |
T3612 |
nsubj |
malformations,are |
R2350 |
T3611 |
T3610 |
amod |
craniofacial,malformations |
R2351 |
T3613 |
T3614 |
det |
the,characteristic |
R2352 |
T3614 |
T3612 |
attr |
characteristic,are |
R2353 |
T3615 |
T3616 |
advmod |
most,obvious |
R2354 |
T3616 |
T3614 |
amod |
obvious,characteristic |
R2355 |
T3617 |
T3614 |
prep |
of,characteristic |
R2356 |
T3618 |
T3619 |
compound |
deH,deH |
R2357 |
T3619 |
T3621 |
compound |
deH,animals |
R2358 |
T3620 |
T3619 |
punct |
/,deH |
R2359 |
T3621 |
T3617 |
pobj |
animals,of |
R2360 |
T3622 |
T3612 |
punct |
", ",are |
R2361 |
T3623 |
T3612 |
prep |
including,are |
R2362 |
T3624 |
T3625 |
advmod |
widely,spaced |
R2363 |
T3625 |
T3626 |
amod |
spaced,eyes |
R2364 |
T3626 |
T3623 |
pobj |
eyes,including |
R2365 |
T3627 |
T3626 |
punct |
", ",eyes |
R2366 |
T3628 |
T3629 |
amod |
small,fissures |
R2367 |
T3629 |
T3626 |
conj |
fissures,eyes |
R2368 |
T3630 |
T3629 |
amod |
palpebral,fissures |
R2369 |
T3631 |
T3629 |
punct |
", ",fissures |
R2370 |
T3632 |
T3633 |
det |
a,area |
R2371 |
T3633 |
T3629 |
conj |
area,fissures |
R2372 |
T3634 |
T3633 |
amod |
broad,area |
R2373 |
T3635 |
T3633 |
amod |
nasal,area |
R2374 |
T3636 |
T3633 |
punct |
", ",area |
R2375 |
T3637 |
T3633 |
cc |
and,area |
R2376 |
T3638 |
T3639 |
det |
a,skull |
R2377 |
T3639 |
T3633 |
conj |
skull,area |
R2378 |
T3640 |
T3639 |
amod |
shortened,skull |
R2379 |
T3641 |
T3639 |
acl |
held,skull |
R2380 |
T3642 |
T3641 |
prep |
in,held |
R2381 |
T3643 |
T3644 |
det |
an,position |
R2382 |
T3644 |
T3642 |
pobj |
position,in |
R2383 |
T3645 |
T3644 |
amod |
elevated,position |
R2384 |
T3646 |
T3639 |
punct |
", ",skull |
R2385 |
T3647 |
T3648 |
dep |
which,causes |
R2386 |
T3648 |
T3639 |
relcl |
causes,skull |
R2387 |
T3649 |
T3648 |
advmod |
presumably,causes |
R2388 |
T3650 |
T3648 |
cc |
or,causes |
R2389 |
T3651 |
T3648 |
conj |
contributes,causes |
R2390 |
T3652 |
T3651 |
prep |
to,contributes |
R2391 |
T3653 |
T3654 |
det |
the,position |
R2392 |
T3654 |
T3651 |
dobj |
position,contributes |
R2393 |
T3655 |
T3654 |
amod |
abnormal,position |
R2394 |
T3656 |
T3654 |
prep |
of,position |
R2395 |
T3657 |
T3658 |
det |
the,ears |
R2396 |
T3658 |
T3656 |
pobj |
ears,of |
R2397 |
T3659 |
T3612 |
punct |
.,are |
R2398 |
T3661 |
T3662 |
nsubj |
We,became |
R2399 |
T3662 |
T3663 |
ccomp |
became,comes |
R2400 |
T3664 |
T3662 |
acomp |
interested,became |
R2401 |
T3665 |
T3664 |
prep |
in,interested |
R2402 |
T3666 |
T3667 |
amod |
droopy,ear |
R2403 |
T3667 |
T3665 |
pobj |
ear,in |
R2404 |
T3668 |
T3669 |
mark |
because,described |
R2405 |
T3669 |
T3662 |
advcl |
described,became |
R2406 |
T3670 |
T3671 |
det |
the,allele |
R2407 |
T3671 |
T3669 |
nsubjpass |
allele,described |
R2408 |
T3672 |
T3671 |
amod |
original,allele |
R2409 |
T3673 |
T3669 |
auxpass |
was,described |
R2410 |
T3674 |
T3675 |
aux |
to,affect |
R2411 |
T3675 |
T3669 |
xcomp |
affect,described |
R2412 |
T3676 |
T3677 |
compound |
pigment,pattern |
R2413 |
T3677 |
T3675 |
dobj |
pattern,affect |
R2414 |
T3678 |
T3675 |
prep |
in,affect |
R2415 |
T3679 |
T3680 |
det |
a,way |
R2416 |
T3680 |
T3678 |
pobj |
way,in |
R2417 |
T3681 |
T3682 |
dep |
that,suggests |
R2418 |
T3682 |
T3680 |
relcl |
suggests,way |
R2419 |
T3683 |
T3684 |
det |
a,transformation |
R2420 |
T3684 |
T3682 |
dobj |
transformation,suggests |
R2421 |
T3685 |
T3684 |
amod |
possible,transformation |
R2422 |
T3686 |
T3684 |
amod |
dorsal,transformation |
R2423 |
T3687 |
T3686 |
prep |
to,dorsal |
R2424 |
T3688 |
T3687 |
amod |
ventral,to |
R2425 |
T3689 |
T3663 |
punct |
: ,comes |
R2426 |
T3690 |
T3663 |
punct |
“,comes |
R2427 |
T3691 |
T3663 |
prep |
On,comes |
R2428 |
T3692 |
T3693 |
det |
a,background |
R2429 |
T3693 |
T3691 |
pobj |
background,On |
R2430 |
T3694 |
T3693 |
amod |
genetic,background |
R2431 |
T3695 |
T3693 |
punct |
(,background |
R2432 |
T3696 |
T3693 |
appos |
at,background |
R2433 |
T3697 |
T3696 |
cc |
and,at |
R2434 |
T3698 |
T3696 |
conj |
AW,at |
R2435 |
T3699 |
T3693 |
punct |
),background |
R2436 |
T3700 |
T3701 |
dep |
which,causes |
R2437 |
T3701 |
T3693 |
relcl |
causes,background |
R2438 |
T3702 |
T3703 |
det |
the,hair |
R2439 |
T3703 |
T3705 |
nsubj |
hair,be |
R2440 |
T3704 |
T3703 |
compound |
belly,hair |
R2441 |
T3705 |
T3701 |
ccomp |
be,causes |
R2442 |
T3706 |
T3705 |
aux |
to,be |
R2443 |
T3707 |
T3705 |
acomp |
lighter,be |
R2444 |
T3708 |
T3707 |
prep |
than,lighter |
R2445 |
T3709 |
T3710 |
det |
the,hair |
R2446 |
T3710 |
T3708 |
pobj |
hair,than |
R2447 |
T3711 |
T3710 |
compound |
back,hair |
R2448 |
T3712 |
T3663 |
punct |
", ",comes |
R2449 |
T3713 |
T3714 |
det |
the,hair |
R2450 |
T3714 |
T3663 |
nsubj |
hair,comes |
R2451 |
T3715 |
T3714 |
compound |
belly,hair |
R2452 |
T3716 |
T3663 |
prt |
up,comes |
R2453 |
T3717 |
T3663 |
advmod |
farther,comes |
R2454 |
T3718 |
T3663 |
prep |
round,comes |
R2455 |
T3719 |
T3720 |
det |
the,sides |
R2456 |
T3720 |
T3718 |
pobj |
sides,round |
R2457 |
T3721 |
T3720 |
prep |
of,sides |
R2458 |
T3722 |
T3723 |
det |
the,body |
R2459 |
T3723 |
T3721 |
pobj |
body,of |
R2460 |
T3724 |
T3723 |
cc |
and,body |
R2461 |
T3725 |
T3723 |
conj |
face,body |
R2462 |
T3726 |
T3663 |
punct |
”,comes |
R2463 |
T3727 |
T3728 |
punct |
(,Curry |
R2464 |
T3728 |
T3663 |
meta |
Curry,comes |
R2465 |
T3729 |
T3728 |
nummod |
1959,Curry |
R2466 |
T3730 |
T3728 |
punct |
),Curry |
R2467 |
T3731 |
T3663 |
punct |
.,comes |
R2468 |
T3733 |
T3734 |
det |
An,pattern |
R2469 |
T3734 |
T3738 |
nsubj |
pattern,is |
R2470 |
T3735 |
T3734 |
amod |
abnormal,pattern |
R2471 |
T3736 |
T3734 |
amod |
dorsoventral,pattern |
R2472 |
T3737 |
T3734 |
compound |
pigment,pattern |
R2473 |
T3739 |
T3740 |
advmod |
readily,apparent |
R2474 |
T3740 |
T3738 |
acomp |
apparent,is |
R2475 |
T3741 |
T3738 |
prep |
in,is |
R2476 |
T3742 |
T3743 |
nmod |
at,at |
R2477 |
T3743 |
T3745 |
nmod |
at,mice |
R2478 |
T3744 |
T3743 |
punct |
/,at |
R2479 |
T3745 |
T3741 |
pobj |
mice,in |
R2480 |
T3746 |
T3743 |
punct |
;,at |
R2481 |
T3747 |
T3748 |
compound |
deH,deH |
R2482 |
T3748 |
T3743 |
appos |
deH,at |
R2483 |
T3749 |
T3748 |
punct |
/,deH |
R2484 |
T3750 |
T3738 |
punct |
", ",is |
R2485 |
T3751 |
T3738 |
cc |
but,is |
R2486 |
T3752 |
T3753 |
nsubjpass |
comparison,described |
R2487 |
T3753 |
T3738 |
conj |
described,is |
R2488 |
T3754 |
T3752 |
prep |
to,comparison |
R2489 |
T3755 |
T3756 |
amod |
nonmutant,animals |
R2490 |
T3756 |
T3754 |
pobj |
animals,to |
R2491 |
T3757 |
T3753 |
auxpass |
is,described |
R2492 |
T3758 |
T3759 |
advmod |
more,accurately |
R2493 |
T3759 |
T3753 |
advmod |
accurately,described |
R2494 |
T3760 |
T3753 |
prep |
in,described |
R2495 |
T3761 |
T3760 |
pobj |
terms,in |
R2496 |
T3762 |
T3761 |
prep |
of,terms |
R2497 |
T3763 |
T3764 |
amod |
ventral,regions |
R2498 |
T3764 |
T3762 |
pobj |
regions,of |
R2499 |
T3765 |
T3763 |
punct |
", ",ventral |
R2500 |
T3766 |
T3763 |
conj |
lateral,ventral |
R2501 |
T3767 |
T3766 |
punct |
", ",lateral |
R2502 |
T3768 |
T3766 |
cc |
and,lateral |
R2503 |
T3769 |
T3766 |
conj |
dorsal,lateral |
R2504 |
T3770 |
T3771 |
punct |
(,1G |
R2505 |
T3771 |
T3753 |
parataxis |
1G,described |
R2506 |
T3772 |
T3771 |
nmod |
Figures,1G |
R2507 |
T3773 |
T3771 |
cc |
and,1G |
R2508 |
T3774 |
T3771 |
conj |
2A,1G |
R2509 |
T3775 |
T3771 |
punct |
),1G |
R2510 |
T3776 |
T3753 |
punct |
.,described |
R2511 |
T3778 |
T3779 |
det |
The,region |
R2512 |
T3779 |
T3781 |
nsubj |
region,has |
R2513 |
T3780 |
T3779 |
amod |
ventral,region |
R2514 |
T3781 |
T3782 |
ccomp |
has,are |
R2515 |
T3783 |
T3784 |
amod |
short,hairs |
R2516 |
T3784 |
T3781 |
dobj |
hairs,has |
R2517 |
T3785 |
T3784 |
prep |
with,hairs |
R2518 |
T3786 |
T3787 |
det |
a,base |
R2519 |
T3787 |
T3785 |
pobj |
base,with |
R2520 |
T3788 |
T3787 |
amod |
gray,base |
R2521 |
T3789 |
T3787 |
cc |
and,base |
R2522 |
T3790 |
T3791 |
npadvmod |
cream,colored |
R2523 |
T3791 |
T3793 |
amod |
colored,tip |
R2524 |
T3792 |
T3791 |
punct |
-,colored |
R2525 |
T3793 |
T3787 |
conj |
tip,base |
R2526 |
T3794 |
T3795 |
poss |
whose,boundary |
R2527 |
T3795 |
T3796 |
dep |
boundary,coincides |
R2528 |
T3796 |
T3784 |
relcl |
coincides,hairs |
R2529 |
T3797 |
T3796 |
prep |
with,coincides |
R2530 |
T3798 |
T3799 |
det |
the,junction |
R2531 |
T3799 |
T3797 |
pobj |
junction,with |
R2532 |
T3800 |
T3801 |
compound |
limb,body |
R2533 |
T3801 |
T3799 |
compound |
body,junction |
R2534 |
T3802 |
T3801 |
punct |
–,body |
R2535 |
T3803 |
T3799 |
compound |
wall,junction |
R2536 |
T3804 |
T3782 |
punct |
;,are |
R2537 |
T3805 |
T3806 |
preconj |
both,appearance |
R2538 |
T3806 |
T3782 |
nsubj |
appearance,are |
R2539 |
T3807 |
T3806 |
det |
the,appearance |
R2540 |
T3808 |
T3806 |
prep |
of,appearance |
R2541 |
T3809 |
T3810 |
det |
this,region |
R2542 |
T3810 |
T3808 |
pobj |
region,of |
R2543 |
T3811 |
T3806 |
cc |
and,appearance |
R2544 |
T3812 |
T3806 |
conj |
position,appearance |
R2545 |
T3813 |
T3812 |
prep |
of,position |
R2546 |
T3814 |
T3815 |
det |
the,boundary |
R2547 |
T3815 |
T3813 |
pobj |
boundary,of |
R2548 |
T3816 |
T3817 |
advmod |
approximately,similar |
R2549 |
T3817 |
T3782 |
acomp |
similar,are |
R2550 |
T3818 |
T3782 |
prep |
in,are |
R2551 |
T3819 |
T3820 |
nmod |
at,at |
R2552 |
T3820 |
T3822 |
nmod |
at,mice |
R2553 |
T3821 |
T3820 |
punct |
/,at |
R2554 |
T3822 |
T3818 |
pobj |
mice,in |
R2555 |
T3823 |
T3820 |
prep |
compared,at |
R2556 |
T3824 |
T3823 |
prep |
to,compared |
R2557 |
T3825 |
T3826 |
compound |
at,at |
R2558 |
T3826 |
T3824 |
pobj |
at,to |
R2559 |
T3827 |
T3826 |
punct |
/,at |
R2560 |
T3828 |
T3826 |
punct |
;,at |
R2561 |
T3829 |
T3830 |
compound |
deH,deH |
R2562 |
T3830 |
T3826 |
appos |
deH,at |
R2563 |
T3831 |
T3830 |
punct |
/,deH |
R2564 |
T3832 |
T3782 |
punct |
.,are |
R2565 |
T3834 |
T3835 |
det |
The,region |
R2566 |
T3835 |
T3837 |
nsubj |
region,contains |
R2567 |
T3836 |
T3835 |
amod |
lateral,region |
R2568 |
T3837 |
T3838 |
ccomp |
contains,appears |
R2569 |
T3839 |
T3840 |
amod |
yellow,hairs |
R2570 |
T3840 |
T3837 |
dobj |
hairs,contains |
R2571 |
T3841 |
T3840 |
prep |
of,hairs |
R2572 |
T3842 |
T3843 |
advmod |
progressively,increasing |
R2573 |
T3843 |
T3844 |
amod |
increasing,length |
R2574 |
T3844 |
T3841 |
pobj |
length,of |
R2575 |
T3845 |
T3838 |
punct |
;,appears |
R2576 |
T3846 |
T3838 |
prep |
in,appears |
R2577 |
T3847 |
T3848 |
compound |
at,at |
R2578 |
T3848 |
T3850 |
compound |
at,mice |
R2579 |
T3849 |
T3848 |
punct |
/,at |
R2580 |
T3850 |
T3846 |
pobj |
mice,in |
R2581 |
T3851 |
T3838 |
punct |
", ",appears |
R2582 |
T3852 |
T3853 |
det |
the,region |
R2583 |
T3853 |
T3838 |
nsubj |
region,appears |
R2584 |
T3854 |
T3853 |
amod |
lateral,region |
R2585 |
T3855 |
T3838 |
prep |
as,appears |
R2586 |
T3856 |
T3857 |
det |
a,stripe |
R2587 |
T3857 |
T3855 |
pobj |
stripe,as |
R2588 |
T3858 |
T3857 |
amod |
thin,stripe |
R2589 |
T3859 |
T3857 |
amod |
yellow,stripe |
R2590 |
T3860 |
T3838 |
prep |
along,appears |
R2591 |
T3861 |
T3862 |
det |
the,flank |
R2592 |
T3862 |
T3860 |
pobj |
flank,along |
R2593 |
T3863 |
T3838 |
punct |
", ",appears |
R2594 |
T3864 |
T3838 |
cc |
but,appears |
R2595 |
T3865 |
T3866 |
prep |
in,is |
R2596 |
T3866 |
T3838 |
conj |
is,appears |
R2597 |
T3867 |
T3868 |
nmod |
at,at |
R2598 |
T3868 |
T3870 |
nmod |
at,mice |
R2599 |
T3869 |
T3868 |
punct |
/,at |
R2600 |
T3870 |
T3865 |
pobj |
mice,in |
R2601 |
T3871 |
T3868 |
punct |
;,at |
R2602 |
T3872 |
T3873 |
compound |
deH,deH |
R2603 |
T3873 |
T3868 |
appos |
deH,at |
R2604 |
T3874 |
T3873 |
punct |
/,deH |
R2605 |
T3875 |
T3866 |
punct |
", ",is |
R2606 |
T3876 |
T3877 |
det |
the,region |
R2607 |
T3877 |
T3866 |
nsubj |
region,is |
R2608 |
T3878 |
T3877 |
amod |
lateral,region |
R2609 |
T3879 |
T3880 |
advmod |
considerably,expanded |
R2610 |
T3880 |
T3866 |
acomp |
expanded,is |
R2611 |
T3881 |
T3866 |
prep |
with,is |
R2612 |
T3882 |
T3883 |
det |
a,boundary |
R2613 |
T3883 |
T3881 |
pobj |
boundary,with |
R2614 |
T3884 |
T3883 |
amod |
diffuse,boundary |
R2615 |
T3885 |
T3883 |
prep |
along,boundary |
R2616 |
T3886 |
T3887 |
det |
the,flank |
R2617 |
T3887 |
T3885 |
pobj |
flank,along |
R2618 |
T3888 |
T3887 |
amod |
dorsal,flank |
R2619 |
T3889 |
T3883 |
punct |
", ",boundary |
R2620 |
T3890 |
T3883 |
cc |
and,boundary |
R2621 |
T3891 |
T3892 |
det |
a,region |
R2622 |
T3892 |
T3883 |
conj |
region,boundary |
R2623 |
T3893 |
T3892 |
amod |
dorsal,region |
R2624 |
T3894 |
T3892 |
amod |
eumelanic,region |
R2625 |
T3895 |
T3896 |
poss |
whose,size |
R2626 |
T3896 |
T3897 |
dep |
size,reduced |
R2627 |
T3897 |
T3892 |
relcl |
reduced,region |
R2628 |
T3898 |
T3897 |
auxpass |
is,reduced |
R2629 |
T3899 |
T3897 |
advmod |
correspondingly,reduced |
R2630 |
T3900 |
T3901 |
punct |
(,2A |
R2631 |
T3901 |
T3866 |
parataxis |
2A,is |
R2632 |
T3902 |
T3901 |
nmod |
Figure,2A |
R2633 |
T3903 |
T3901 |
cc |
and,2A |
R2634 |
T3904 |
T3901 |
conj |
2B,2A |
R2635 |
T3905 |
T3901 |
punct |
),2A |
R2636 |
T3906 |
T3838 |
punct |
.,appears |
R2637 |
T3908 |
T3909 |
amod |
Total,size |
R2638 |
T3909 |
T3911 |
nsubj |
size,is |
R2639 |
T3910 |
T3909 |
compound |
body,size |
R2640 |
T3912 |
T3911 |
acomp |
smaller,is |
R2641 |
T3913 |
T3911 |
prep |
in,is |
R2642 |
T3914 |
T3913 |
pobj |
mutant,in |
R2643 |
T3915 |
T3914 |
prep |
compared,mutant |
R2644 |
T3916 |
T3915 |
prep |
to,compared |
R2645 |
T3917 |
T3916 |
pobj |
nonmutant,to |
R2646 |
T3918 |
T3914 |
appos |
animals,mutant |
R2647 |
T3919 |
T3911 |
punct |
", ",is |
R2648 |
T3920 |
T3911 |
cc |
but,is |
R2649 |
T3921 |
T3922 |
det |
the,proportion |
R2650 |
T3922 |
T3923 |
nsubjpass |
proportion,increased |
R2651 |
T3923 |
T3911 |
conj |
increased,is |
R2652 |
T3924 |
T3922 |
prep |
of,proportion |
R2653 |
T3925 |
T3926 |
compound |
body,circumference |
R2654 |
T3926 |
T3924 |
pobj |
circumference,of |
R2655 |
T3927 |
T3922 |
acl |
occupied,proportion |
R2656 |
T3928 |
T3927 |
agent |
by,occupied |
R2657 |
T3929 |
T3930 |
det |
the,region |
R2658 |
T3930 |
T3928 |
pobj |
region,by |
R2659 |
T3931 |
T3930 |
amod |
lateral,region |
R2660 |
T3932 |
T3927 |
prep |
in,occupied |
R2661 |
T3933 |
T3934 |
amod |
mutant,animals |
R2662 |
T3934 |
T3932 |
pobj |
animals,in |
R2663 |
T3935 |
T3923 |
auxpass |
is,increased |
R2664 |
T3936 |
T3937 |
advmod |
about,2 |
R2665 |
T3937 |
T3938 |
quantmod |
2,fold |
R2666 |
T3938 |
T3923 |
advmod |
fold,increased |
R2667 |
T3939 |
T3938 |
punct |
-,fold |
R2668 |
T3940 |
T3923 |
punct |
", ",increased |
R2669 |
T3941 |
T3923 |
prep |
from,increased |
R2670 |
T3942 |
T3943 |
nummod |
11.9,% |
R2671 |
T3943 |
T3941 |
pobj |
%,from |
R2672 |
T3944 |
T3923 |
prep |
to,increased |
R2673 |
T3945 |
T3946 |
nummod |
22.2,% |
R2674 |
T3946 |
T3944 |
pobj |
%,to |
R2675 |
T3947 |
T3948 |
punct |
(,Figure |
R2676 |
T3948 |
T3923 |
parataxis |
Figure,increased |
R2677 |
T3949 |
T3948 |
nummod |
2C,Figure |
R2678 |
T3950 |
T3948 |
punct |
),Figure |
R2679 |
T3951 |
T3923 |
punct |
.,increased |
R2680 |
T3953 |
T3954 |
det |
The,proportion |
R2681 |
T3954 |
T3955 |
nsubjpass |
proportion,expanded |
R2682 |
T3956 |
T3954 |
prep |
of,proportion |
R2683 |
T3957 |
T3958 |
det |
the,region |
R2684 |
T3958 |
T3956 |
pobj |
region,of |
R2685 |
T3959 |
T3958 |
amod |
ventral,region |
R2686 |
T3960 |
T3961 |
npadvmod |
cream,colored |
R2687 |
T3961 |
T3958 |
amod |
colored,region |
R2688 |
T3962 |
T3961 |
punct |
-,colored |
R2689 |
T3963 |
T3955 |
auxpass |
is,expanded |
R2690 |
T3964 |
T3955 |
advmod |
also,expanded |
R2691 |
T3965 |
T3966 |
det |
a,amount |
R2692 |
T3966 |
T3955 |
npadvmod |
amount,expanded |
R2693 |
T3967 |
T3966 |
amod |
small,amount |
R2694 |
T3968 |
T3966 |
punct |
", ",amount |
R2695 |
T3969 |
T3970 |
nummod |
47.9,% |
R2696 |
T3970 |
T3966 |
appos |
%,amount |
R2697 |
T3971 |
T3955 |
prep |
in,expanded |
R2698 |
T3972 |
T3971 |
pobj |
mutant,in |
R2699 |
T3973 |
T3955 |
prep |
compared,expanded |
R2700 |
T3974 |
T3973 |
prep |
to,compared |
R2701 |
T3975 |
T3976 |
nummod |
37.8,% |
R2702 |
T3976 |
T3974 |
pobj |
%,to |
R2703 |
T3977 |
T3976 |
prep |
in,% |
R2704 |
T3978 |
T3977 |
pobj |
nonmutant,in |
R2705 |
T3979 |
T3955 |
dobj |
animals,expanded |
R2706 |
T3980 |
T3955 |
punct |
", ",expanded |
R2707 |
T3981 |
T3955 |
cc |
but,expanded |
R2708 |
T3982 |
T3983 |
nsubj |
expansion,is |
R2709 |
T3983 |
T3955 |
conj |
is,expanded |
R2710 |
T3984 |
T3982 |
prep |
of,expansion |
R2711 |
T3985 |
T3986 |
det |
the,region |
R2712 |
T3986 |
T3984 |
pobj |
region,of |
R2713 |
T3987 |
T3986 |
amod |
lateral,region |
R2714 |
T3988 |
T3982 |
punct |
", ",expansion |
R2715 |
T3989 |
T3990 |
dep |
which,occurs |
R2716 |
T3990 |
T3982 |
relcl |
occurs,expansion |
R2717 |
T3991 |
T3990 |
prep |
at,occurs |
R2718 |
T3992 |
T3993 |
det |
all,levels |
R2719 |
T3993 |
T3991 |
pobj |
levels,at |
R2720 |
T3994 |
T3993 |
prep |
of,levels |
R2721 |
T3995 |
T3996 |
det |
the,body |
R2722 |
T3996 |
T3994 |
pobj |
body,of |
R2723 |
T3997 |
T3993 |
punct |
", ",levels |
R2724 |
T3998 |
T3993 |
prep |
including,levels |
R2725 |
T3999 |
T4000 |
det |
the,limbs |
R2726 |
T4000 |
T3998 |
pobj |
limbs,including |
R2727 |
T4001 |
T4000 |
cc |
and,limbs |
R2728 |
T4002 |
T4003 |
det |
the,cranium |
R2729 |
T4003 |
T4000 |
conj |
cranium,limbs |
R2730 |
T4004 |
T4000 |
punct |
(,limbs |
R2731 |
T4005 |
T4000 |
cc |
but,limbs |
R2732 |
T4006 |
T4005 |
neg |
not,but |
R2733 |
T4007 |
T4008 |
det |
the,pad |
R2734 |
T4008 |
T4000 |
conj |
pad,limbs |
R2735 |
T4009 |
T4008 |
compound |
whisker,pad |
R2736 |
T4010 |
T4008 |
punct |
),pad |
R2737 |
T4011 |
T3983 |
punct |
", ",is |
R2738 |
T4012 |
T4013 |
det |
the,feature |
R2739 |
T4013 |
T3983 |
attr |
feature,is |
R2740 |
T4014 |
T4013 |
amod |
major,feature |
R2741 |
T4015 |
T4013 |
amod |
responsible,feature |
R2742 |
T4016 |
T4015 |
prep |
for,responsible |
R2743 |
T4017 |
T4018 |
det |
the,appearance |
R2744 |
T4018 |
T4016 |
pobj |
appearance,for |
R2745 |
T4019 |
T4018 |
amod |
ventralized,appearance |
R2746 |
T4020 |
T4018 |
acl |
caused,appearance |
R2747 |
T4021 |
T4020 |
agent |
by,caused |
R2748 |
T4022 |
T4021 |
pobj |
deH,by |
R2749 |
T4023 |
T3983 |
punct |
.,is |
R2750 |
T4025 |
T4026 |
aux |
To,investigate |
R2751 |
T4026 |
T4027 |
advcl |
investigate,examined |
R2752 |
T4028 |
T4029 |
mark |
whether,affects |
R2753 |
T4029 |
T4026 |
ccomp |
affects,investigate |
R2754 |
T4030 |
T4029 |
nsubj |
deH,affects |
R2755 |
T4031 |
T4032 |
amod |
other,characteristics |
R2756 |
T4032 |
T4029 |
dobj |
characteristics,affects |
R2757 |
T4033 |
T4032 |
amod |
dorsoventral,characteristics |
R2758 |
T4034 |
T4032 |
compound |
skin,characteristics |
R2759 |
T4035 |
T4032 |
prep |
besides,characteristics |
R2760 |
T4036 |
T4037 |
compound |
pigment,type |
R2761 |
T4037 |
T4035 |
pobj |
type,besides |
R2762 |
T4038 |
T4037 |
punct |
-,type |
R2763 |
T4039 |
T4037 |
amod |
switching,type |
R2764 |
T4040 |
T4027 |
punct |
", ",examined |
R2765 |
T4041 |
T4027 |
nsubj |
we,examined |
R2766 |
T4042 |
T4043 |
poss |
its,effects |
R2767 |
T4043 |
T4027 |
dobj |
effects,examined |
R2768 |
T4044 |
T4043 |
prep |
on,effects |
R2769 |
T4045 |
T4046 |
compound |
hair,length |
R2770 |
T4046 |
T4044 |
pobj |
length,on |
R2771 |
T4047 |
T4046 |
cc |
and,length |
R2772 |
T4048 |
T4046 |
conj |
pigmentation,length |
R2773 |
T4049 |
T4027 |
prep |
in,examined |
R2774 |
T4050 |
T4051 |
det |
an,background |
R2775 |
T4051 |
T4049 |
pobj |
background,in |
R2776 |
T4052 |
T4053 |
compound |
ae,ae |
R2777 |
T4053 |
T4051 |
compound |
ae,background |
R2778 |
T4054 |
T4053 |
punct |
/,ae |
R2779 |
T4055 |
T4027 |
punct |
.,examined |
R2780 |
T4057 |
T4058 |
advmod |
Overall,causes |
R2781 |
T4058 |
T4061 |
ccomp |
causes,is |
R2782 |
T4059 |
T4058 |
punct |
", ",causes |
R2783 |
T4060 |
T4058 |
nsubj |
deH,causes |
R2784 |
T4062 |
T4063 |
det |
a,reduction |
R2785 |
T4063 |
T4058 |
dobj |
reduction,causes |
R2786 |
T4064 |
T4063 |
amod |
small,reduction |
R2787 |
T4065 |
T4064 |
cc |
but,small |
R2788 |
T4066 |
T4064 |
conj |
consistent,small |
R2789 |
T4067 |
T4063 |
prep |
in,reduction |
R2790 |
T4068 |
T4069 |
compound |
hair,length |
R2791 |
T4069 |
T4067 |
pobj |
length,in |
R2792 |
T4070 |
T4058 |
prep |
in,causes |
R2793 |
T4071 |
T4072 |
preconj |
both,dorsum |
R2794 |
T4072 |
T4070 |
pobj |
dorsum,in |
R2795 |
T4073 |
T4072 |
cc |
and,dorsum |
R2796 |
T4074 |
T4072 |
conj |
ventrum,dorsum |
R2797 |
T4075 |
T4061 |
punct |
;,is |
R2798 |
T4076 |
T4077 |
advmod |
when,normalized |
R2799 |
T4077 |
T4061 |
advcl |
normalized,is |
R2800 |
T4078 |
T4079 |
amod |
mutant,animals |
R2801 |
T4079 |
T4077 |
nsubjpass |
animals,normalized |
R2802 |
T4080 |
T4078 |
cc |
and,mutant |
R2803 |
T4081 |
T4078 |
conj |
nonmutant,mutant |
R2804 |
T4082 |
T4077 |
auxpass |
are,normalized |
R2805 |
T4083 |
T4077 |
prep |
for,normalized |
R2806 |
T4084 |
T4085 |
compound |
body,circumference |
R2807 |
T4085 |
T4083 |
pobj |
circumference,for |
R2808 |
T4086 |
T4061 |
punct |
", ",is |
R2809 |
T4087 |
T4088 |
amod |
reduced,length |
R2810 |
T4088 |
T4061 |
nsubj |
length,is |
R2811 |
T4089 |
T4088 |
compound |
hair,length |
R2812 |
T4090 |
T4091 |
advmod |
most,apparent |
R2813 |
T4091 |
T4061 |
acomp |
apparent,is |
R2814 |
T4092 |
T4061 |
prep |
in,is |
R2815 |
T4093 |
T4094 |
det |
the,region |
R2816 |
T4094 |
T4092 |
pobj |
region,in |
R2817 |
T4095 |
T4094 |
amod |
lateral,region |
R2818 |
T4096 |
T4097 |
punct |
(,Figure |
R2819 |
T4097 |
T4061 |
parataxis |
Figure,is |
R2820 |
T4098 |
T4097 |
nummod |
2E,Figure |
R2821 |
T4099 |
T4097 |
punct |
),Figure |
R2822 |
T4100 |
T4061 |
punct |
.,is |
R2823 |
T4102 |
T4103 |
amod |
Adult,animals |
R2824 |
T4103 |
T4111 |
nsubj |
animals,exhibit |
R2825 |
T4104 |
T4105 |
nmod |
ae,ae |
R2826 |
T4105 |
T4103 |
nmod |
ae,animals |
R2827 |
T4106 |
T4105 |
punct |
/,ae |
R2828 |
T4107 |
T4105 |
punct |
;,ae |
R2829 |
T4108 |
T4109 |
compound |
deH,deH |
R2830 |
T4109 |
T4105 |
appos |
deH,ae |
R2831 |
T4110 |
T4109 |
punct |
/,deH |
R2832 |
T4112 |
T4113 |
compound |
body,size |
R2833 |
T4113 |
T4115 |
compound |
size,reduction |
R2834 |
T4114 |
T4113 |
punct |
-,size |
R2835 |
T4115 |
T4111 |
dobj |
reduction,exhibit |
R2836 |
T4116 |
T4115 |
cc |
and,reduction |
R2837 |
T4117 |
T4118 |
amod |
skeletal,abnormalities |
R2838 |
T4118 |
T4115 |
conj |
abnormalities,reduction |
R2839 |
T4119 |
T4111 |
punct |
", ",exhibit |
R2840 |
T4120 |
T4111 |
cc |
but,exhibit |
R2841 |
T4121 |
T4111 |
conj |
display,exhibit |
R2842 |
T4122 |
T4123 |
det |
no,phenotype |
R2843 |
T4123 |
T4121 |
dobj |
phenotype,display |
R2844 |
T4124 |
T4125 |
compound |
coat,color |
R2845 |
T4125 |
T4123 |
compound |
color,phenotype |
R2846 |
T4126 |
T4125 |
punct |
-,color |
R2847 |
T4127 |
T4128 |
punct |
(,shown |
R2848 |
T4128 |
T4121 |
parataxis |
shown,display |
R2849 |
T4129 |
T4128 |
nsubj |
data,shown |
R2850 |
T4130 |
T4128 |
neg |
not,shown |
R2851 |
T4131 |
T4128 |
punct |
),shown |
R2852 |
T4132 |
T4111 |
punct |
.,exhibit |
R2853 |
T4134 |
T4135 |
advmod |
However,are |
R2854 |
T4136 |
T4135 |
punct |
", ",are |
R2855 |
T4137 |
T4138 |
nmod |
ae,ae |
R2856 |
T4138 |
T4140 |
nmod |
ae,neonates |
R2857 |
T4139 |
T4138 |
punct |
/,ae |
R2858 |
T4140 |
T4135 |
nsubj |
neonates,are |
R2859 |
T4141 |
T4138 |
cc |
and,ae |
R2860 |
T4142 |
T4143 |
nmod |
ae,ae |
R2861 |
T4143 |
T4138 |
conj |
ae,ae |
R2862 |
T4144 |
T4143 |
punct |
/,ae |
R2863 |
T4145 |
T4143 |
punct |
;,ae |
R2864 |
T4146 |
T4147 |
compound |
deH,deH |
R2865 |
T4147 |
T4143 |
appos |
deH,ae |
R2866 |
T4148 |
T4147 |
punct |
/,deH |
R2867 |
T4149 |
T4135 |
advmod |
clearly,are |
R2868 |
T4150 |
T4135 |
acomp |
distinguishable,are |
R2869 |
T4151 |
T4135 |
prep |
in,are |
R2870 |
T4152 |
T4153 |
det |
the,days |
R2871 |
T4153 |
T4151 |
pobj |
days,in |
R2872 |
T4154 |
T4153 |
amod |
first,days |
R2873 |
T4155 |
T4153 |
amod |
few,days |
R2874 |
T4156 |
T4153 |
prep |
after,days |
R2875 |
T4157 |
T4156 |
pobj |
birth,after |
R2876 |
T4158 |
T4135 |
punct |
", ",are |
R2877 |
T4159 |
T4160 |
advmod |
when,is |
R2878 |
T4160 |
T4135 |
advcl |
is,are |
R2879 |
T4161 |
T4162 |
det |
a,gradient |
R2880 |
T4162 |
T4160 |
nsubj |
gradient,is |
R2881 |
T4163 |
T4162 |
amod |
dorsoventral,gradient |
R2882 |
T4164 |
T4162 |
prep |
of,gradient |
R2883 |
T4165 |
T4166 |
amod |
melanogenic,activity |
R2884 |
T4166 |
T4164 |
pobj |
activity,of |
R2885 |
T4167 |
T4160 |
acomp |
apparent,is |
R2886 |
T4168 |
T4160 |
prep |
under,is |
R2887 |
T4169 |
T4170 |
det |
the,skin |
R2888 |
T4170 |
T4168 |
pobj |
skin,under |
R2889 |
T4171 |
T4172 |
punct |
(,Figure |
R2890 |
T4172 |
T4135 |
parataxis |
Figure,are |
R2891 |
T4173 |
T4172 |
nummod |
2D,Figure |
R2892 |
T4174 |
T4172 |
punct |
),Figure |
R2893 |
T4175 |
T4135 |
punct |
.,are |
R2894 |
T4177 |
T4178 |
prep |
At,is |
R2895 |
T4179 |
T4180 |
det |
this,stage |
R2896 |
T4180 |
T4177 |
pobj |
stage,At |
R2897 |
T4181 |
T4178 |
punct |
", ",is |
R2898 |
T4182 |
T4183 |
compound |
melanoblast,migration |
R2899 |
T4183 |
T4178 |
nsubj |
migration,is |
R2900 |
T4184 |
T4183 |
prep |
from,migration |
R2901 |
T4185 |
T4186 |
det |
the,crest |
R2902 |
T4186 |
T4184 |
pobj |
crest,from |
R2903 |
T4187 |
T4186 |
amod |
neural,crest |
R2904 |
T4188 |
T4189 |
advmod |
mostly,complete |
R2905 |
T4189 |
T4178 |
acomp |
complete,is |
R2906 |
T4190 |
T4178 |
punct |
", ",is |
R2907 |
T4191 |
T4178 |
cc |
but,is |
R2908 |
T4192 |
T4193 |
expl |
there,is |
R2909 |
T4193 |
T4178 |
conj |
is,is |
R2910 |
T4194 |
T4195 |
det |
a,gradient |
R2911 |
T4195 |
T4193 |
attr |
gradient,is |
R2912 |
T4196 |
T4195 |
amod |
dorsoventral,gradient |
R2913 |
T4197 |
T4195 |
prep |
in,gradient |
R2914 |
T4198 |
T4199 |
compound |
melanocyte,differentiation |
R2915 |
T4199 |
T4197 |
pobj |
differentiation,in |
R2916 |
T4200 |
T4199 |
cc |
and,differentiation |
R2917 |
T4201 |
T4202 |
compound |
pigment,synthesis |
R2918 |
T4202 |
T4199 |
conj |
synthesis,differentiation |
R2919 |
T4203 |
T4178 |
punct |
.,is |
R2920 |
T4205 |
T4206 |
det |
The,skin |
R2921 |
T4206 |
T4207 |
nsubj |
skin,appears |
R2922 |
T4208 |
T4206 |
prep |
of,skin |
R2923 |
T4209 |
T4210 |
compound |
ae,ae |
R2924 |
T4210 |
T4212 |
compound |
ae,neonates |
R2925 |
T4211 |
T4210 |
punct |
/,ae |
R2926 |
T4212 |
T4208 |
pobj |
neonates,of |
R2927 |
T4213 |
T4214 |
advmod |
uniformly,dark |
R2928 |
T4214 |
T4207 |
oprd |
dark,appears |
R2929 |
T4215 |
T4207 |
prep |
over,appears |
R2930 |
T4216 |
T4217 |
det |
the,dorsum |
R2931 |
T4217 |
T4215 |
pobj |
dorsum,over |
R2932 |
T4218 |
T4217 |
amod |
entire,dorsum |
R2933 |
T4219 |
T4207 |
punct |
", ",appears |
R2934 |
T4220 |
T4207 |
cc |
but,appears |
R2935 |
T4221 |
T4222 |
prep |
in,is |
R2936 |
T4222 |
T4207 |
conj |
is,appears |
R2937 |
T4223 |
T4224 |
nmod |
ae,ae |
R2938 |
T4224 |
T4226 |
nmod |
ae,neonates |
R2939 |
T4225 |
T4224 |
punct |
/,ae |
R2940 |
T4226 |
T4221 |
pobj |
neonates,in |
R2941 |
T4227 |
T4224 |
punct |
;,ae |
R2942 |
T4228 |
T4229 |
compound |
deH,deH |
R2943 |
T4229 |
T4224 |
appos |
deH,ae |
R2944 |
T4230 |
T4229 |
punct |
/,deH |
R2945 |
T4231 |
T4222 |
punct |
", ",is |
R2946 |
T4232 |
T4233 |
det |
the,area |
R2947 |
T4233 |
T4222 |
nsubj |
area,is |
R2948 |
T4234 |
T4233 |
prep |
of,area |
R2949 |
T4235 |
T4236 |
amod |
dark,skin |
R2950 |
T4236 |
T4234 |
pobj |
skin,of |
R2951 |
T4237 |
T4238 |
advmod |
more,restricted |
R2952 |
T4238 |
T4222 |
acomp |
restricted,is |
R2953 |
T4239 |
T4222 |
punct |
", ",is |
R2954 |
T4240 |
T4241 |
advmod |
particularly,above |
R2955 |
T4241 |
T4222 |
prep |
above,is |
R2956 |
T4242 |
T4243 |
det |
the,limbs |
R2957 |
T4243 |
T4241 |
pobj |
limbs,above |
R2958 |
T4244 |
T4222 |
punct |
", ",is |
R2959 |
T4245 |
T4222 |
cc |
and,is |
R2960 |
T4246 |
T4222 |
conj |
resembles,is |
R2961 |
T4247 |
T4248 |
det |
the,pattern |
R2962 |
T4248 |
T4246 |
dobj |
pattern,resembles |
R2963 |
T4249 |
T4248 |
prep |
of,pattern |
R2964 |
T4250 |
T4251 |
amod |
dorsal,eumelanin |
R2965 |
T4251 |
T4249 |
pobj |
eumelanin,of |
R2966 |
T4252 |
T4248 |
prep |
in,pattern |
R2967 |
T4253 |
T4254 |
nmod |
at,at |
R2968 |
T4254 |
T4256 |
nmod |
at,animals |
R2969 |
T4255 |
T4254 |
punct |
/,at |
R2970 |
T4256 |
T4252 |
pobj |
animals,in |
R2971 |
T4257 |
T4254 |
punct |
;,at |
R2972 |
T4258 |
T4259 |
compound |
deH,deH |
R2973 |
T4259 |
T4254 |
appos |
deH,at |
R2974 |
T4260 |
T4259 |
punct |
/,deH |
R2975 |
T4261 |
T4256 |
amod |
adult,animals |
R2976 |
T4262 |
T4222 |
punct |
.,is |
R2977 |
T4264 |
T4265 |
advcl |
Taken,suggest |
R2978 |
T4266 |
T4264 |
advmod |
together,Taken |
R2979 |
T4267 |
T4265 |
punct |
", ",suggest |
R2980 |
T4268 |
T4269 |
det |
these,observations |
R2981 |
T4269 |
T4265 |
nsubj |
observations,suggest |
R2982 |
T4270 |
T4271 |
mark |
that,interferes |
R2983 |
T4271 |
T4265 |
ccomp |
interferes,suggest |
R2984 |
T4272 |
T4271 |
nsubj |
deH,interferes |
R2985 |
T4273 |
T4271 |
prep |
with,interferes |
R2986 |
T4274 |
T4275 |
det |
the,establishment |
R2987 |
T4275 |
T4273 |
pobj |
establishment,with |
R2988 |
T4276 |
T4275 |
prep |
of,establishment |
R2989 |
T4277 |
T4278 |
amod |
dorsoventral,patterning |
R2990 |
T4278 |
T4276 |
pobj |
patterning,of |
R2991 |
T4279 |
T4271 |
prep |
during,interferes |
R2992 |
T4280 |
T4281 |
compound |
skin,development |
R2993 |
T4281 |
T4279 |
pobj |
development,during |
R2994 |
T4282 |
T4271 |
prep |
by,interferes |
R2995 |
T4283 |
T4282 |
pcomp |
causing,by |
R2996 |
T4284 |
T4285 |
amod |
dorsal,expansion |
R2997 |
T4285 |
T4283 |
dobj |
expansion,causing |
R2998 |
T4286 |
T4285 |
prep |
of,expansion |
R2999 |
T4287 |
T4288 |
det |
a,region |
R3000 |
T4288 |
T4286 |
pobj |
region,of |
R3001 |
T4289 |
T4288 |
amod |
lateral,region |
R3002 |
T4290 |
T4291 |
dep |
that,is |
R3003 |
T4291 |
T4288 |
relcl |
is,region |
R3004 |
T4292 |
T4291 |
advmod |
normally,is |
R3005 |
T4293 |
T4294 |
quantmod |
3,5 |
R3006 |
T4294 |
T4296 |
nummod |
5,mm |
R3007 |
T4295 |
T4294 |
punct |
–,5 |
R3008 |
T4296 |
T4291 |
attr |
mm,is |
R3009 |
T4297 |
T4296 |
prep |
in,mm |
R3010 |
T4298 |
T4297 |
pobj |
width,in |
R3011 |
T4299 |
T4265 |
punct |
.,suggest |
R3012 |
T4301 |
T4302 |
det |
This,region |
R3013 |
T4302 |
T4304 |
nsubj |
region,serve |
R3014 |
T4303 |
T4302 |
amod |
same,region |
R3015 |
T4305 |
T4304 |
aux |
may,serve |
R3016 |
T4306 |
T4304 |
prep |
as,serve |
R3017 |
T4307 |
T4308 |
det |
a,boundary |
R3018 |
T4308 |
T4306 |
pobj |
boundary,as |
R3019 |
T4309 |
T4308 |
prep |
between,boundary |
R3020 |
T4310 |
T4311 |
amod |
dorsal,skin |
R3021 |
T4311 |
T4309 |
pobj |
skin,between |
R3022 |
T4312 |
T4310 |
cc |
and,dorsal |
R3023 |
T4313 |
T4310 |
conj |
ventral,dorsal |
R3024 |
T4314 |
T4304 |
prep |
by,serve |
R3025 |
T4315 |
T4314 |
pcomp |
inhibiting,by |
R3026 |
T4316 |
T4317 |
compound |
melanocyte,differentiation |
R3027 |
T4317 |
T4315 |
dobj |
differentiation,inhibiting |
R3028 |
T4318 |
T4314 |
punct |
", ",by |
R3029 |
T4319 |
T4314 |
conj |
by,by |
R3030 |
T4320 |
T4319 |
pcomp |
promoting,by |
R3031 |
T4321 |
T4322 |
compound |
pheomelanin,synthesis |
R3032 |
T4322 |
T4320 |
dobj |
synthesis,promoting |
R3033 |
T4323 |
T4319 |
punct |
", ",by |
R3034 |
T4324 |
T4319 |
cc |
and,by |
R3035 |
T4325 |
T4319 |
conj |
by,by |
R3036 |
T4326 |
T4325 |
pcomp |
supporting,by |
R3037 |
T4327 |
T4328 |
det |
a,increase |
R3038 |
T4328 |
T4326 |
dobj |
increase,supporting |
R3039 |
T4329 |
T4328 |
amod |
progressive,increase |
R3040 |
T4330 |
T4328 |
prep |
in,increase |
R3041 |
T4331 |
T4332 |
compound |
hair,growth |
R3042 |
T4332 |
T4330 |
pobj |
growth,in |
R3043 |
T4333 |
T4328 |
prep |
from,increase |
R3044 |
T4334 |
T4333 |
pobj |
ventrum,from |
R3045 |
T4335 |
T4328 |
prep |
to,increase |
R3046 |
T4336 |
T4335 |
pobj |
dorsum,to |
R3047 |
T4337 |
T4304 |
punct |
.,serve |
R3048 |
T4339 |
T4340 |
mark |
As,described |
R3049 |
T4340 |
T4341 |
advcl |
described,expressed |
R3050 |
T4342 |
T4340 |
advmod |
below,described |
R3051 |
T4343 |
T4341 |
punct |
", ",expressed |
R3052 |
T4344 |
T4345 |
det |
the,gene |
R3053 |
T4345 |
T4341 |
nsubjpass |
gene,expressed |
R3054 |
T4346 |
T4345 |
amod |
defective,gene |
R3055 |
T4347 |
T4346 |
prep |
in,defective |
R3056 |
T4348 |
T4347 |
pobj |
deH,in |
R3057 |
T4349 |
T4345 |
punct |
", ",gene |
R3058 |
T4350 |
T4345 |
appos |
Tbx15,gene |
R3059 |
T4351 |
T4341 |
punct |
", ",expressed |
R3060 |
T4352 |
T4341 |
auxpass |
is,expressed |
R3061 |
T4353 |
T4341 |
advmod |
normally,expressed |
R3062 |
T4354 |
T4341 |
prep |
in,expressed |
R3063 |
T4355 |
T4356 |
det |
the,region |
R3064 |
T4356 |
T4354 |
pobj |
region,in |
R3065 |
T4357 |
T4356 |
amod |
dorsal,region |
R3066 |
T4358 |
T4341 |
cc |
and,expressed |
R3067 |
T4359 |
T4360 |
advmod |
therefore,is |
R3068 |
T4360 |
T4341 |
conj |
is,expressed |
R3069 |
T4361 |
T4360 |
acomp |
likely,is |
R3070 |
T4362 |
T4363 |
aux |
to,play |
R3071 |
T4363 |
T4361 |
xcomp |
play,likely |
R3072 |
T4364 |
T4365 |
det |
a,role |
R3073 |
T4365 |
T4363 |
dobj |
role,play |
R3074 |
T4366 |
T4363 |
prep |
in,play |
R3075 |
T4367 |
T4366 |
pcomp |
establishing,in |
R3076 |
T4368 |
T4369 |
det |
the,size |
R3077 |
T4369 |
T4367 |
dobj |
size,establishing |
R3078 |
T4370 |
T4369 |
cc |
and,size |
R3079 |
T4371 |
T4372 |
amod |
dorsal,extent |
R3080 |
T4372 |
T4369 |
conj |
extent,size |
R3081 |
T4373 |
T4369 |
prep |
of,size |
R3082 |
T4374 |
T4375 |
det |
the,region |
R3083 |
T4375 |
T4373 |
pobj |
region,of |
R3084 |
T4376 |
T4375 |
amod |
lateral,region |
R3085 |
T4377 |
T4341 |
punct |
.,expressed |