PMC:314463 / 13385-14700 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T3068 0-11 NNS denotes Differences
T3070 12-19 IN denotes between
T3071 20-26 JJ denotes dorsal
T3073 27-30 CC denotes and
T3074 31-38 JJ denotes ventral
T3072 39-51 NN denotes pigmentation
T3075 52-54 IN denotes of
T3076 55-57 NN denotes at
T3078 57-58 HYPH denotes /
T3077 58-60 NN denotes at
T3079 61-65 NNS denotes mice
T3080 66-69 VBP denotes are
T3081 70-77 RB denotes usually
T3069 78-88 VBN denotes attributed
T3082 89-91 IN denotes to
T3083 92-99 NN denotes pigment
T3085 99-100 HYPH denotes -
T3084 100-104 NN denotes type
T3086 105-116 NNS denotes differences
T3087 117-123 VBN denotes caused
T3088 124-126 IN denotes by
T3089 127-134 JJ denotes ventral
T3091 134-135 HYPH denotes -
T3090 135-143 JJ denotes specific
T3092 144-154 NN denotes expression
T3093 155-157 IN denotes of
T3094 158-164 NN denotes Agouti
T3095 164-166 , denotes ,
T3096 166-169 CC denotes but
T3097 170-177 NNS denotes animals
T3099 178-188 JJ denotes homozygous
T3100 189-192 IN denotes for
T3101 193-194 DT denotes a
T3103 195-199 JJ denotes null
T3102 200-206 NN denotes allele
T3104 207-209 IN denotes of
T3105 210-216 NN denotes Agouti
T3106 216-218 , denotes ,
T3107 218-225 JJ denotes extreme
T3108 226-235 NN denotes nonagouti
T3109 236-237 -LRB- denotes (
T3110 237-239 NN denotes ae
T3111 239-240 -RRB- denotes )
T3112 240-242 , denotes ,
T3098 242-246 VBP denotes have
T3113 247-254 JJ denotes ventral
T3114 255-260 NNS denotes hairs
T3115 261-265 WDT denotes that
T3116 266-273 VBP denotes contain
T3117 274-278 JJR denotes less
T3118 279-286 NN denotes melanin
T3119 287-291 IN denotes than
T3120 292-298 JJ denotes dorsal
T3121 299-304 NNS denotes hairs
T3122 304-306 , denotes ,
T3123 306-312 VBG denotes giving
T3124 313-314 DT denotes a
T3126 315-323 RB denotes slightly
T3127 324-329 JJ denotes paler
T3125 330-340 NN denotes appearance
T3128 341-343 IN denotes to
T3129 344-347 DT denotes the
T3131 348-355 JJ denotes ventral
T3130 356-360 NN denotes coat
T3132 361-362 -LRB- denotes (
T3133 362-368 NN denotes Figure
T3134 369-371 CD denotes 1G
T3135 371-372 -RRB- denotes )
T3136 372-373 . denotes .
T3137 373-545 sentence denotes Using DOPA staining as an indicator of tyrosinase activity, we observed a gradual dorsoventral transition in isolated dermis preparations from P4.5 ae/ae mice (Figure 1G).
T3138 374-379 VBG denotes Using
T3140 380-384 NN denotes DOPA
T3141 385-393 NN denotes staining
T3142 394-396 IN denotes as
T3143 397-399 DT denotes an
T3144 400-409 NN denotes indicator
T3145 410-412 IN denotes of
T3146 413-423 NN denotes tyrosinase
T3147 424-432 NN denotes activity
T3148 432-434 , denotes ,
T3149 434-436 PRP denotes we
T3139 437-445 VBD denotes observed
T3150 446-447 DT denotes a
T3152 448-455 JJ denotes gradual
T3153 456-468 JJ denotes dorsoventral
T3151 469-479 NN denotes transition
T3154 480-482 IN denotes in
T3155 483-491 VBN denotes isolated
T3157 492-498 NN denotes dermis
T3156 499-511 NNS denotes preparations
T3158 512-516 IN denotes from
T3159 517-521 NN denotes P4.5
T3161 522-524 NN denotes ae
T3163 524-525 HYPH denotes /
T3162 525-527 NN denotes ae
T3160 528-532 NNS denotes mice
T3164 533-534 -LRB- denotes (
T3165 534-540 NN denotes Figure
T3166 541-543 CD denotes 1G
T3167 543-544 -RRB- denotes )
T3168 544-545 . denotes .
T3169 545-790 sentence denotes By contrast, skin from at/at mice reveal an abrupt dorsoventral transition of DOPA staining, which probably reflects the additive effects of reduced melanin content (as in ae/ae mice) and downregulation of tyrosinase activity induced by Agouti.
T3170 546-548 IN denotes By
T3172 549-557 NN denotes contrast
T3173 557-559 , denotes ,
T3174 559-563 NN denotes skin
T3175 564-568 IN denotes from
T3176 569-571 NN denotes at
T3178 571-572 HYPH denotes /
T3177 572-574 NN denotes at
T3179 575-579 NNS denotes mice
T3171 580-586 VBP denotes reveal
T3180 587-589 DT denotes an
T3182 590-596 JJ denotes abrupt
T3183 597-609 JJ denotes dorsoventral
T3181 610-620 NN denotes transition
T3184 621-623 IN denotes of
T3185 624-628 NN denotes DOPA
T3186 629-637 NN denotes staining
T3187 637-639 , denotes ,
T3188 639-644 WDT denotes which
T3190 645-653 RB denotes probably
T3189 654-662 VBZ denotes reflects
T3191 663-666 DT denotes the
T3193 667-675 JJ denotes additive
T3192 676-683 NNS denotes effects
T3194 684-686 IN denotes of
T3195 687-694 VBN denotes reduced
T3197 695-702 NN denotes melanin
T3196 703-710 NN denotes content
T3198 711-712 -LRB- denotes (
T3199 712-714 IN denotes as
T3200 715-717 IN denotes in
T3201 718-720 NN denotes ae
T3203 720-721 HYPH denotes /
T3202 721-723 NN denotes ae
T3204 724-728 NNS denotes mice
T3205 728-729 -RRB- denotes )
T3206 730-733 CC denotes and
T3207 734-748 NN denotes downregulation
T3208 749-751 IN denotes of
T3209 752-762 NN denotes tyrosinase
T3210 763-771 NN denotes activity
T3211 772-779 VBN denotes induced
T3212 780-782 IN denotes by
T3213 783-789 NN denotes Agouti
T3214 789-790 . denotes .
T3215 790-923 sentence denotes Melanin content of individual hairs is likely to be influenced both by the number of pigment cells and their follicular environment.
T3216 791-798 NN denotes Melanin
T3217 799-806 NN denotes content
T3219 807-809 IN denotes of
T3220 810-820 JJ denotes individual
T3221 821-826 NNS denotes hairs
T3218 827-829 VBZ denotes is
T3222 830-836 JJ denotes likely
T3223 837-839 TO denotes to
T3225 840-842 VB denotes be
T3224 843-853 VBN denotes influenced
T3226 854-858 CC denotes both
T3227 859-861 IN denotes by
T3228 862-865 DT denotes the
T3229 866-872 NN denotes number
T3230 873-875 IN denotes of
T3231 876-883 NN denotes pigment
T3232 884-889 NNS denotes cells
T3233 890-893 CC denotes and
T3234 894-899 PRP$ denotes their
T3236 900-910 JJ denotes follicular
T3235 911-922 NN denotes environment
T3237 922-923 . denotes .
T3238 923-1106 sentence denotes Regardless, dorsoventral differences in hair pigment content of ae/ae mice persist throughout multiple hair cycles into adulthood, similar to hair length (but unlike skin thickness).
T3239 924-934 RB denotes Regardless
T3241 934-936 , denotes ,
T3242 936-948 JJ denotes dorsoventral
T3243 949-960 NNS denotes differences
T3244 961-963 IN denotes in
T3245 964-968 NN denotes hair
T3247 969-976 NN denotes pigment
T3246 977-984 NN denotes content
T3248 985-987 IN denotes of
T3249 988-990 NN denotes ae
T3251 990-991 HYPH denotes /
T3250 991-993 NN denotes ae
T3252 994-998 NNS denotes mice
T3240 999-1006 VBP denotes persist
T3253 1007-1017 IN denotes throughout
T3254 1018-1026 JJ denotes multiple
T3256 1027-1031 NN denotes hair
T3255 1032-1038 NNS denotes cycles
T3257 1039-1043 IN denotes into
T3258 1044-1053 NN denotes adulthood
T3259 1053-1055 , denotes ,
T3260 1055-1062 JJ denotes similar
T3261 1063-1065 IN denotes to
T3262 1066-1070 NN denotes hair
T3263 1071-1077 NN denotes length
T3264 1078-1079 -LRB- denotes (
T3265 1079-1082 CC denotes but
T3266 1083-1089 IN denotes unlike
T3267 1090-1094 NN denotes skin
T3268 1095-1104 NN denotes thickness
T3269 1104-1105 -RRB- denotes )
T3270 1105-1106 . denotes .
T3271 1106-1315 sentence denotes Thus, at least three characteristics distinguish dorsal from ventral skin: differences in pigment-type synthesis (depending on Agouti genotype), differences in hair length, and differences in melanin content.
T3272 1107-1111 RB denotes Thus
T3274 1111-1113 , denotes ,
T3275 1113-1115 RB denotes at
T3277 1116-1121 RBS denotes least
T3276 1122-1127 CD denotes three
T3278 1128-1143 NNS denotes characteristics
T3273 1144-1155 VBP denotes distinguish
T3279 1156-1162 JJ denotes dorsal
T3280 1163-1167 IN denotes from
T3281 1168-1175 JJ denotes ventral
T3282 1176-1180 NN denotes skin
T3283 1180-1182 : denotes :
T3284 1182-1193 NNS denotes differences
T3285 1194-1196 IN denotes in
T3286 1197-1204 NN denotes pigment
T3288 1204-1205 HYPH denotes -
T3287 1205-1209 NN denotes type
T3289 1210-1219 NN denotes synthesis
T3290 1220-1221 -LRB- denotes (
T3291 1221-1230 VBG denotes depending
T3292 1231-1233 IN denotes on
T3293 1234-1240 NN denotes Agouti
T3294 1241-1249 NN denotes genotype
T3295 1249-1250 -RRB- denotes )
T3296 1250-1252 , denotes ,
T3297 1252-1263 NNS denotes differences
T3298 1264-1266 IN denotes in
T3299 1267-1271 NN denotes hair
T3300 1272-1278 NN denotes length
T3301 1278-1280 , denotes ,
T3302 1280-1283 CC denotes and
T3303 1284-1295 NNS denotes differences
T3304 1296-1298 IN denotes in
T3305 1299-1306 NN denotes melanin
T3306 1307-1314 NN denotes content
T3307 1314-1315 . denotes .
R2047 T3068 T3069 nsubjpass Differences,attributed
R2048 T3070 T3068 prep between,Differences
R2049 T3071 T3072 amod dorsal,pigmentation
R2050 T3072 T3070 pobj pigmentation,between
R2051 T3073 T3071 cc and,dorsal
R2052 T3074 T3071 conj ventral,dorsal
R2053 T3075 T3072 prep of,pigmentation
R2054 T3076 T3077 compound at,at
R2055 T3077 T3079 compound at,mice
R2056 T3078 T3077 punct /,at
R2057 T3079 T3075 pobj mice,of
R2058 T3080 T3069 auxpass are,attributed
R2059 T3081 T3069 advmod usually,attributed
R2060 T3082 T3069 prep to,attributed
R2061 T3083 T3084 compound pigment,type
R2062 T3084 T3086 compound type,differences
R2063 T3085 T3084 punct -,type
R2064 T3086 T3082 pobj differences,to
R2065 T3087 T3086 acl caused,differences
R2066 T3088 T3087 agent by,caused
R2067 T3089 T3090 amod ventral,specific
R2068 T3090 T3092 amod specific,expression
R2069 T3091 T3090 punct -,specific
R2070 T3092 T3088 pobj expression,by
R2071 T3093 T3092 prep of,expression
R2072 T3094 T3093 pobj Agouti,of
R2073 T3095 T3069 punct ", ",attributed
R2074 T3096 T3069 cc but,attributed
R2075 T3097 T3098 nsubj animals,have
R2076 T3098 T3069 conj have,attributed
R2077 T3099 T3097 amod homozygous,animals
R2078 T3100 T3099 prep for,homozygous
R2079 T3101 T3102 det a,allele
R2080 T3102 T3100 pobj allele,for
R2081 T3103 T3102 amod null,allele
R2082 T3104 T3102 prep of,allele
R2083 T3105 T3104 pobj Agouti,of
R2084 T3106 T3102 punct ", ",allele
R2085 T3107 T3108 amod extreme,nonagouti
R2086 T3108 T3102 appos nonagouti,allele
R2087 T3109 T3108 punct (,nonagouti
R2088 T3110 T3108 appos ae,nonagouti
R2089 T3111 T3108 punct ),nonagouti
R2090 T3112 T3098 punct ", ",have
R2091 T3113 T3114 amod ventral,hairs
R2092 T3114 T3098 dobj hairs,have
R2093 T3115 T3116 dep that,contain
R2094 T3116 T3114 relcl contain,hairs
R2095 T3117 T3118 amod less,melanin
R2096 T3118 T3116 dobj melanin,contain
R2097 T3119 T3118 prep than,melanin
R2098 T3120 T3121 amod dorsal,hairs
R2099 T3121 T3119 pobj hairs,than
R2100 T3122 T3116 punct ", ",contain
R2101 T3123 T3116 advcl giving,contain
R2102 T3124 T3125 det a,appearance
R2103 T3125 T3123 dobj appearance,giving
R2104 T3126 T3127 advmod slightly,paler
R2105 T3127 T3125 amod paler,appearance
R2106 T3128 T3123 dative to,giving
R2107 T3129 T3130 det the,coat
R2108 T3130 T3128 pobj coat,to
R2109 T3131 T3130 amod ventral,coat
R2110 T3132 T3133 punct (,Figure
R2111 T3133 T3098 parataxis Figure,have
R2112 T3134 T3133 nummod 1G,Figure
R2113 T3135 T3133 punct ),Figure
R2114 T3136 T3098 punct .,have
R2115 T3138 T3139 advcl Using,observed
R2116 T3140 T3141 compound DOPA,staining
R2117 T3141 T3138 dobj staining,Using
R2118 T3142 T3138 prep as,Using
R2119 T3143 T3144 det an,indicator
R2120 T3144 T3142 pobj indicator,as
R2121 T3145 T3144 prep of,indicator
R2122 T3146 T3147 compound tyrosinase,activity
R2123 T3147 T3145 pobj activity,of
R2124 T3148 T3139 punct ", ",observed
R2125 T3149 T3139 nsubj we,observed
R2126 T3150 T3151 det a,transition
R2127 T3151 T3139 dobj transition,observed
R2128 T3152 T3151 amod gradual,transition
R2129 T3153 T3151 amod dorsoventral,transition
R2130 T3154 T3139 prep in,observed
R2131 T3155 T3156 amod isolated,preparations
R2132 T3156 T3154 pobj preparations,in
R2133 T3157 T3156 compound dermis,preparations
R2134 T3158 T3156 prep from,preparations
R2135 T3159 T3160 compound P4.5,mice
R2136 T3160 T3158 pobj mice,from
R2137 T3161 T3162 compound ae,ae
R2138 T3162 T3160 compound ae,mice
R2139 T3163 T3162 punct /,ae
R2140 T3164 T3165 punct (,Figure
R2141 T3165 T3139 parataxis Figure,observed
R2142 T3166 T3165 nummod 1G,Figure
R2143 T3167 T3165 punct ),Figure
R2144 T3168 T3139 punct .,observed
R2145 T3170 T3171 prep By,reveal
R2146 T3172 T3170 pobj contrast,By
R2147 T3173 T3171 punct ", ",reveal
R2148 T3174 T3171 nsubj skin,reveal
R2149 T3175 T3174 prep from,skin
R2150 T3176 T3177 compound at,at
R2151 T3177 T3179 compound at,mice
R2152 T3178 T3177 punct /,at
R2153 T3179 T3175 pobj mice,from
R2154 T3180 T3181 det an,transition
R2155 T3181 T3171 dobj transition,reveal
R2156 T3182 T3181 amod abrupt,transition
R2157 T3183 T3181 amod dorsoventral,transition
R2158 T3184 T3181 prep of,transition
R2159 T3185 T3186 compound DOPA,staining
R2160 T3186 T3184 pobj staining,of
R2161 T3187 T3181 punct ", ",transition
R2162 T3188 T3189 dep which,reflects
R2163 T3189 T3181 relcl reflects,transition
R2164 T3190 T3189 advmod probably,reflects
R2165 T3191 T3192 det the,effects
R2166 T3192 T3189 dobj effects,reflects
R2167 T3193 T3192 amod additive,effects
R2168 T3194 T3192 prep of,effects
R2169 T3195 T3196 amod reduced,content
R2170 T3196 T3194 pobj content,of
R2171 T3197 T3196 compound melanin,content
R2172 T3198 T3196 punct (,content
R2173 T3199 T3196 prep as,content
R2174 T3200 T3199 prep in,as
R2175 T3201 T3202 compound ae,ae
R2176 T3202 T3204 compound ae,mice
R2177 T3203 T3202 punct /,ae
R2178 T3204 T3200 pobj mice,in
R2179 T3205 T3192 punct ),effects
R2180 T3206 T3192 cc and,effects
R2181 T3207 T3192 conj downregulation,effects
R2182 T3208 T3207 prep of,downregulation
R2183 T3209 T3210 compound tyrosinase,activity
R2184 T3210 T3208 pobj activity,of
R2185 T3211 T3210 acl induced,activity
R2186 T3212 T3211 agent by,induced
R2187 T3213 T3212 pobj Agouti,by
R2188 T3214 T3171 punct .,reveal
R2189 T3216 T3217 compound Melanin,content
R2190 T3217 T3218 nsubj content,is
R2191 T3219 T3217 prep of,content
R2192 T3220 T3221 amod individual,hairs
R2193 T3221 T3219 pobj hairs,of
R2194 T3222 T3218 acomp likely,is
R2195 T3223 T3224 aux to,influenced
R2196 T3224 T3222 xcomp influenced,likely
R2197 T3225 T3224 auxpass be,influenced
R2198 T3226 T3227 preconj both,by
R2199 T3227 T3224 agent by,influenced
R2200 T3228 T3229 det the,number
R2201 T3229 T3227 pobj number,by
R2202 T3230 T3229 prep of,number
R2203 T3231 T3232 compound pigment,cells
R2204 T3232 T3230 pobj cells,of
R2205 T3233 T3229 cc and,number
R2206 T3234 T3235 poss their,environment
R2207 T3235 T3229 conj environment,number
R2208 T3236 T3235 amod follicular,environment
R2209 T3237 T3218 punct .,is
R2210 T3239 T3240 advmod Regardless,persist
R2211 T3241 T3240 punct ", ",persist
R2212 T3242 T3243 amod dorsoventral,differences
R2213 T3243 T3240 nsubj differences,persist
R2214 T3244 T3243 prep in,differences
R2215 T3245 T3246 compound hair,content
R2216 T3246 T3244 pobj content,in
R2217 T3247 T3246 compound pigment,content
R2218 T3248 T3246 prep of,content
R2219 T3249 T3250 compound ae,ae
R2220 T3250 T3252 compound ae,mice
R2221 T3251 T3250 punct /,ae
R2222 T3252 T3248 pobj mice,of
R2223 T3253 T3240 prep throughout,persist
R2224 T3254 T3255 amod multiple,cycles
R2225 T3255 T3253 pobj cycles,throughout
R2226 T3256 T3255 compound hair,cycles
R2227 T3257 T3240 prep into,persist
R2228 T3258 T3257 pobj adulthood,into
R2229 T3259 T3240 punct ", ",persist
R2230 T3260 T3240 advcl similar,persist
R2231 T3261 T3260 prep to,similar
R2232 T3262 T3263 compound hair,length
R2233 T3263 T3261 pobj length,to
R2234 T3264 T3260 punct (,similar
R2235 T3265 T3260 cc but,similar
R2236 T3266 T3260 conj unlike,similar
R2237 T3267 T3268 compound skin,thickness
R2238 T3268 T3266 pobj thickness,unlike
R2239 T3269 T3240 punct ),persist
R2240 T3270 T3240 punct .,persist
R2241 T3272 T3273 advmod Thus,distinguish
R2242 T3274 T3273 punct ", ",distinguish
R2243 T3275 T3276 advmod at,three
R2244 T3276 T3278 nummod three,characteristics
R2245 T3277 T3276 advmod least,three
R2246 T3278 T3273 nsubj characteristics,distinguish
R2247 T3279 T3273 dative dorsal,distinguish
R2248 T3280 T3273 prep from,distinguish
R2249 T3281 T3280 pobj ventral,from
R2250 T3282 T3273 dobj skin,distinguish
R2251 T3283 T3273 punct : ,distinguish
R2252 T3284 T3273 dobj differences,distinguish
R2253 T3285 T3284 prep in,differences
R2254 T3286 T3287 compound pigment,type
R2255 T3287 T3289 compound type,synthesis
R2256 T3288 T3287 punct -,type
R2257 T3289 T3285 pobj synthesis,in
R2258 T3290 T3284 punct (,differences
R2259 T3291 T3284 prep depending,differences
R2260 T3292 T3291 prep on,depending
R2261 T3293 T3294 compound Agouti,genotype
R2262 T3294 T3292 pobj genotype,on
R2263 T3295 T3284 punct ),differences
R2264 T3296 T3284 punct ", ",differences
R2265 T3297 T3284 conj differences,differences
R2266 T3298 T3297 prep in,differences
R2267 T3299 T3300 compound hair,length
R2268 T3300 T3298 pobj length,in
R2269 T3301 T3297 punct ", ",differences
R2270 T3302 T3297 cc and,differences
R2271 T3303 T3297 conj differences,differences
R2272 T3304 T3303 prep in,differences
R2273 T3305 T3306 compound melanin,content
R2274 T3306 T3304 pobj content,in
R2275 T3307 T3273 punct .,distinguish