PMC:1941754 / 30713-31470 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T6565 0-7 JJ denotes Genetic
T6566 8-19 NNS denotes experiments
T6568 20-22 IN denotes in
T6569 23-25 NNP denotes S.
T6570 26-36 NNP denotes cerevisiae
T6567 37-45 VBD denotes provided
T6571 46-54 NN denotes evidence
T6572 55-59 IN denotes that
T6574 60-63 DT denotes the
T6576 64-73 NN denotes pachytene
T6575 74-84 NN denotes checkpoint
T6573 85-93 VBZ denotes monitors
T6577 94-97 CC denotes and
T6578 98-106 VBZ denotes responds
T6579 107-109 IN denotes to
T6580 110-125 JJ denotes recombinational
T6582 126-129 NN denotes DSB
T6581 130-136 NN denotes repair
T6583 137-140 CC denotes and
T6584 141-149 NN denotes synapsis
T6585 150-163 RB denotes independently
T6586 163-164 . denotes .
T6587 164-300 sentence denotes Wu and Burgess concluded that the repair checkpoint is RAD17-SAE2 dependent, while the synapsis checkpoint is PCH2-ZIP1 dependent [12].
T6588 165-167 NNP denotes Wu
T6590 168-171 CC denotes and
T6591 172-179 NNP denotes Burgess
T6589 180-189 VBD denotes concluded
T6592 190-194 IN denotes that
T6594 195-198 DT denotes the
T6596 199-205 NN denotes repair
T6595 206-216 NN denotes checkpoint
T6593 217-219 VBZ denotes is
T6597 220-225 NN denotes RAD17
T6599 225-226 HYPH denotes -
T6598 226-230 NN denotes SAE2
T6600 231-240 JJ denotes dependent
T6601 240-242 , denotes ,
T6602 242-247 IN denotes while
T6604 248-251 DT denotes the
T6606 252-260 NN denotes synapsis
T6605 261-271 NN denotes checkpoint
T6603 272-274 VBZ denotes is
T6607 275-279 NN denotes PCH2
T6609 279-280 HYPH denotes -
T6608 280-284 NN denotes ZIP1
T6610 285-294 JJ denotes dependent
T6611 295-296 -LRB- denotes [
T6612 296-298 CD denotes 12
T6613 298-299 -RRB- denotes ]
T6614 299-300 . denotes .
T6615 300-520 sentence denotes Of these four genes, SAE2 and ZIP1 do not have clear mammalian orthologs (although SYCP1 may be a functional ortholog of ZIP1), and mutation of the mouse RAD17 ortholog, Rad1, presumably causes embryonic lethality [42].
T6616 301-303 IN denotes Of
T6618 304-309 DT denotes these
T6620 310-314 CD denotes four
T6619 315-320 NNS denotes genes
T6621 320-322 , denotes ,
T6622 322-326 NN denotes SAE2
T6623 327-330 CC denotes and
T6624 331-335 NN denotes ZIP1
T6625 336-338 VBP denotes do
T6626 339-342 RB denotes not
T6617 343-347 VB denotes have
T6627 348-353 JJ denotes clear
T6629 354-363 JJ denotes mammalian
T6628 364-373 NNS denotes orthologs
T6630 374-375 -LRB- denotes (
T6631 375-383 IN denotes although
T6633 384-389 NN denotes SYCP1
T6634 390-393 MD denotes may
T6632 394-396 VB denotes be
T6635 397-398 DT denotes a
T6637 399-409 JJ denotes functional
T6636 410-418 NN denotes ortholog
T6638 419-421 IN denotes of
T6639 422-426 NN denotes ZIP1
T6640 426-427 -RRB- denotes )
T6641 427-429 , denotes ,
T6642 429-432 CC denotes and
T6643 433-441 NN denotes mutation
T6645 442-444 IN denotes of
T6646 445-448 DT denotes the
T6648 449-454 NN denotes mouse
T6649 455-460 NN denotes RAD17
T6647 461-469 NN denotes ortholog
T6650 469-471 , denotes ,
T6651 471-475 NN denotes Rad1
T6652 475-477 , denotes ,
T6653 477-487 RB denotes presumably
T6644 488-494 VBZ denotes causes
T6654 495-504 JJ denotes embryonic
T6655 505-514 NN denotes lethality
T6656 515-516 -LRB- denotes [
T6657 516-518 CD denotes 42
T6658 518-519 -RRB- denotes ]
T6659 519-520 . denotes .
T6660 520-757 sentence denotes Thus, mutational analysis of mouse Pch2 (Trip13), which is also critical for the synapsis checkpoint in C. elegans [2], was the best remaining option to evaluate potential functional conservation in mammalian meiotic checkpoint control.
T6661 521-525 RB denotes Thus
T6663 525-527 , denotes ,
T6664 527-537 JJ denotes mutational
T6665 538-546 NN denotes analysis
T6666 547-549 IN denotes of
T6667 550-555 NN denotes mouse
T6668 556-560 NN denotes Pch2
T6669 561-562 -LRB- denotes (
T6670 562-568 NN denotes Trip13
T6671 568-569 -RRB- denotes )
T6672 569-571 , denotes ,
T6673 571-576 WDT denotes which
T6674 577-579 VBZ denotes is
T6675 580-584 RB denotes also
T6676 585-593 JJ denotes critical
T6677 594-597 IN denotes for
T6678 598-601 DT denotes the
T6680 602-610 NN denotes synapsis
T6679 611-621 NN denotes checkpoint
T6681 622-624 IN denotes in
T6682 625-627 NNP denotes C.
T6683 628-635 NNP denotes elegans
T6684 636-637 -LRB- denotes [
T6685 637-638 CD denotes 2
T6686 638-639 -RRB- denotes ]
T6687 639-641 , denotes ,
T6662 641-644 VBD denotes was
T6688 645-648 DT denotes the
T6690 649-653 JJS denotes best
T6691 654-663 JJ denotes remaining
T6689 664-670 NN denotes option
T6692 671-673 TO denotes to
T6693 674-682 VB denotes evaluate
T6694 683-692 JJ denotes potential
T6696 693-703 JJ denotes functional
T6695 704-716 NN denotes conservation
T6697 717-719 IN denotes in
T6698 720-729 JJ denotes mammalian
T6700 730-737 JJ denotes meiotic
T6701 738-748 NN denotes checkpoint
T6699 749-756 NN denotes control
T6702 756-757 . denotes .
R4005 T6565 T6566 amod Genetic,experiments
R4006 T6566 T6567 nsubj experiments,provided
R4007 T6568 T6566 prep in,experiments
R4008 T6569 T6570 compound S.,cerevisiae
R4009 T6570 T6568 pobj cerevisiae,in
R4010 T6571 T6567 dobj evidence,provided
R4011 T6572 T6573 mark that,monitors
R4012 T6573 T6571 acl monitors,evidence
R4013 T6574 T6575 det the,checkpoint
R4014 T6575 T6573 nsubj checkpoint,monitors
R4015 T6576 T6575 compound pachytene,checkpoint
R4016 T6577 T6573 cc and,monitors
R4017 T6578 T6573 conj responds,monitors
R4018 T6579 T6578 prep to,responds
R4019 T6580 T6581 amod recombinational,repair
R4020 T6581 T6573 dobj repair,monitors
R4021 T6582 T6581 compound DSB,repair
R4022 T6583 T6581 cc and,repair
R4023 T6584 T6581 conj synapsis,repair
R4024 T6585 T6573 advmod independently,monitors
R4025 T6586 T6567 punct .,provided
R4026 T6588 T6589 nsubj Wu,concluded
R4027 T6590 T6588 cc and,Wu
R4028 T6591 T6588 conj Burgess,Wu
R4029 T6592 T6593 mark that,is
R4030 T6593 T6589 ccomp is,concluded
R4031 T6594 T6595 det the,checkpoint
R4032 T6595 T6593 nsubj checkpoint,is
R4033 T6596 T6595 compound repair,checkpoint
R4034 T6597 T6598 compound RAD17,SAE2
R4035 T6598 T6600 npadvmod SAE2,dependent
R4036 T6599 T6598 punct -,SAE2
R4037 T6600 T6593 acomp dependent,is
R4038 T6601 T6593 punct ", ",is
R4039 T6602 T6603 mark while,is
R4040 T6603 T6593 advcl is,is
R4041 T6604 T6605 det the,checkpoint
R4042 T6605 T6603 nsubj checkpoint,is
R4043 T6606 T6605 compound synapsis,checkpoint
R4044 T6607 T6608 compound PCH2,ZIP1
R4045 T6608 T6610 npadvmod ZIP1,dependent
R4046 T6609 T6608 punct -,ZIP1
R4047 T6610 T6603 acomp dependent,is
R4048 T6611 T6612 punct [,12
R4049 T6612 T6589 parataxis 12,concluded
R4050 T6613 T6612 punct ],12
R4051 T6614 T6589 punct .,concluded
R4052 T6616 T6617 prep Of,have
R4053 T6618 T6619 det these,genes
R4054 T6619 T6616 pobj genes,Of
R4055 T6620 T6619 nummod four,genes
R4056 T6621 T6617 punct ", ",have
R4057 T6622 T6617 nsubj SAE2,have
R4058 T6623 T6622 cc and,SAE2
R4059 T6624 T6622 conj ZIP1,SAE2
R4060 T6625 T6617 aux do,have
R4061 T6626 T6617 neg not,have
R4062 T6627 T6628 amod clear,orthologs
R4063 T6628 T6617 dobj orthologs,have
R4064 T6629 T6628 amod mammalian,orthologs
R4065 T6630 T6617 punct (,have
R4066 T6631 T6632 mark although,be
R4067 T6632 T6617 advcl be,have
R4068 T6633 T6632 nsubj SYCP1,be
R4069 T6634 T6632 aux may,be
R4070 T6635 T6636 det a,ortholog
R4071 T6636 T6632 attr ortholog,be
R4072 T6637 T6636 amod functional,ortholog
R4073 T6638 T6636 prep of,ortholog
R4074 T6639 T6638 pobj ZIP1,of
R4075 T6640 T6617 punct ),have
R4076 T6641 T6617 punct ", ",have
R4077 T6642 T6617 cc and,have
R4078 T6643 T6644 nsubj mutation,causes
R4079 T6644 T6617 conj causes,have
R4080 T6645 T6643 prep of,mutation
R4081 T6646 T6647 det the,ortholog
R4082 T6647 T6645 pobj ortholog,of
R4083 T6648 T6649 compound mouse,RAD17
R4084 T6649 T6647 compound RAD17,ortholog
R4085 T6650 T6647 punct ", ",ortholog
R4086 T6651 T6647 appos Rad1,ortholog
R4087 T6652 T6644 punct ", ",causes
R4088 T6653 T6644 advmod presumably,causes
R4089 T6654 T6655 amod embryonic,lethality
R4090 T6655 T6644 dobj lethality,causes
R4091 T6656 T6657 punct [,42
R4092 T6657 T6644 parataxis 42,causes
R4093 T6658 T6657 punct ],42
R4094 T6659 T6644 punct .,causes
R4095 T6661 T6662 advmod Thus,was
R4096 T6663 T6662 punct ", ",was
R4097 T6664 T6665 amod mutational,analysis
R4098 T6665 T6662 nsubj analysis,was
R4099 T6666 T6665 prep of,analysis
R4100 T6667 T6668 compound mouse,Pch2
R4101 T6668 T6666 pobj Pch2,of
R4102 T6669 T6668 punct (,Pch2
R4103 T6670 T6668 appos Trip13,Pch2
R4104 T6671 T6665 punct ),analysis
R4105 T6672 T6665 punct ", ",analysis
R4106 T6673 T6674 dep which,is
R4107 T6674 T6665 relcl is,analysis
R4108 T6675 T6674 advmod also,is
R4109 T6676 T6674 acomp critical,is
R4110 T6677 T6676 prep for,critical
R4111 T6678 T6679 det the,checkpoint
R4112 T6679 T6677 pobj checkpoint,for
R4113 T6680 T6679 compound synapsis,checkpoint
R4114 T6681 T6674 prep in,is
R4115 T6682 T6683 compound C.,elegans
R4116 T6683 T6681 pobj elegans,in
R4117 T6684 T6685 punct [,2
R4118 T6685 T6674 parataxis 2,is
R4119 T6686 T6685 punct ],2
R4120 T6687 T6662 punct ", ",was
R4121 T6688 T6689 det the,option
R4122 T6689 T6662 attr option,was
R4123 T6690 T6689 amod best,option
R4124 T6691 T6689 amod remaining,option
R4125 T6692 T6693 aux to,evaluate
R4126 T6693 T6662 advcl evaluate,was
R4127 T6694 T6695 amod potential,conservation
R4128 T6695 T6693 dobj conservation,evaluate
R4129 T6696 T6695 amod functional,conservation
R4130 T6697 T6695 prep in,conservation
R4131 T6698 T6699 amod mammalian,control
R4132 T6699 T6697 pobj control,in
R4133 T6700 T6701 amod meiotic,checkpoint
R4134 T6701 T6699 compound checkpoint,control
R4135 T6702 T6662 punct .,was