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PMC:1914394 / 50726-52209 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T26609 0-7 JJ denotes Ectopic
T26610 8-16 NN denotes Division
T26611 17-20 CC denotes and
T26612 21-36 NN denotes Differentiation
T26613 36-219 sentence denotes Rb is critical to ensure that many types of terminally differentiating cells leave the cell cycle (e.g., neurons, gut and skin epithelia, muscle, and lens fibres) (reviewed in [66]).
T26614 37-39 NN denotes Rb
T26615 40-42 VBZ denotes is
T26616 43-51 JJ denotes critical
T26617 52-54 TO denotes to
T26618 55-61 VB denotes ensure
T26619 62-66 IN denotes that
T26621 67-71 JJ denotes many
T26622 72-77 NNS denotes types
T26623 78-80 IN denotes of
T26624 81-91 RB denotes terminally
T26625 92-107 VBG denotes differentiating
T26626 108-113 NNS denotes cells
T26620 114-119 VBP denotes leave
T26627 120-123 DT denotes the
T26629 124-128 NN denotes cell
T26628 129-134 NN denotes cycle
T26630 135-136 -LRB- denotes (
T26631 136-140 FW denotes e.g.
T26633 140-142 , denotes ,
T26632 142-149 NNS denotes neurons
T26634 149-151 , denotes ,
T26635 151-154 NN denotes gut
T26637 155-158 CC denotes and
T26638 159-163 NN denotes skin
T26636 164-173 NNS denotes epithelia
T26639 173-175 , denotes ,
T26640 175-181 NN denotes muscle
T26641 181-183 , denotes ,
T26642 183-186 CC denotes and
T26643 187-191 NN denotes lens
T26644 192-198 NNS denotes fibres
T26645 198-199 -RRB- denotes )
T26646 200-201 -LRB- denotes (
T26647 201-209 VBN denotes reviewed
T26648 210-212 IN denotes in
T26649 213-214 -LRB- denotes [
T26650 214-216 CD denotes 66
T26651 216-217 -RRB- denotes ]
T26652 217-218 -RRB- denotes )
T26653 218-219 . denotes .
T26654 219-421 sentence denotes Early overexpression studies in vitro suggested Rb might temper expansion of cycling cells, but KO studies in vivo indicate that its major role is to block division in terminally differentiating cells.
T26655 220-225 JJ denotes Early
T26657 226-240 NN denotes overexpression
T26656 241-248 NNS denotes studies
T26659 249-251 FW denotes in
T26660 252-257 FW denotes vitro
T26658 258-267 VBN denotes suggested
T26661 268-270 NN denotes Rb
T26663 271-276 MD denotes might
T26662 277-283 VB denotes temper
T26664 284-293 NN denotes expansion
T26665 294-296 IN denotes of
T26666 297-304 NN denotes cycling
T26667 305-310 NNS denotes cells
T26668 310-312 , denotes ,
T26669 312-315 CC denotes but
T26670 316-318 NN denotes KO
T26671 319-326 NNS denotes studies
T26673 327-329 FW denotes in
T26674 330-334 FW denotes vivo
T26672 335-343 VBP denotes indicate
T26675 344-348 IN denotes that
T26677 349-352 PRP$ denotes its
T26679 353-358 JJ denotes major
T26678 359-363 NN denotes role
T26676 364-366 VBZ denotes is
T26680 367-369 TO denotes to
T26681 370-375 VB denotes block
T26682 376-384 NN denotes division
T26683 385-387 IN denotes in
T26684 388-398 RB denotes terminally
T26685 399-414 VBG denotes differentiating
T26686 415-420 NNS denotes cells
T26687 420-421 . denotes .
T26688 421-524 sentence denotes In its absence, many (but clearly not all) aspects of differentiation go ahead relatively unperturbed.
T26689 422-424 IN denotes In
T26691 425-428 PRP$ denotes its
T26692 429-436 NN denotes absence
T26693 436-438 , denotes ,
T26694 438-442 JJ denotes many
T26695 443-444 -LRB- denotes (
T26696 444-447 CC denotes but
T26697 448-455 RB denotes clearly
T26698 456-459 RB denotes not
T26699 460-463 DT denotes all
T26701 463-464 -RRB- denotes )
T26700 465-472 NNS denotes aspects
T26702 473-475 IN denotes of
T26703 476-491 NN denotes differentiation
T26690 492-494 VBP denotes go
T26704 495-500 RP denotes ahead
T26705 501-511 RB denotes relatively
T26706 512-523 JJ denotes unperturbed
T26707 523-524 . denotes .
T26708 524-686 sentence denotes In the retina, differentiating transition cells are born in the absence of Rb, migrate to the correct layer, and express appropriate markers ([2] and this work).
T26709 525-527 IN denotes In
T26711 528-531 DT denotes the
T26712 532-538 NN denotes retina
T26713 538-540 , denotes ,
T26714 540-555 VBG denotes differentiating
T26716 556-566 NN denotes transition
T26715 567-572 NNS denotes cells
T26717 573-576 VBP denotes are
T26710 577-581 VBN denotes born
T26718 582-584 IN denotes in
T26719 585-588 DT denotes the
T26720 589-596 NN denotes absence
T26721 597-599 IN denotes of
T26722 600-602 NN denotes Rb
T26723 602-604 , denotes ,
T26724 604-611 VBP denotes migrate
T26725 612-614 IN denotes to
T26726 615-618 DT denotes the
T26728 619-626 JJ denotes correct
T26727 627-632 NN denotes layer
T26729 632-634 , denotes ,
T26730 634-637 CC denotes and
T26731 638-645 VBP denotes express
T26732 646-657 JJ denotes appropriate
T26733 658-665 NNS denotes markers
T26734 666-667 -LRB- denotes (
T26736 667-668 -LRB- denotes [
T26735 668-669 CD denotes 2
T26737 669-670 -RRB- denotes ]
T26738 671-674 CC denotes and
T26739 675-679 DT denotes this
T26740 680-684 NN denotes work
T26741 684-685 -RRB- denotes )
T26742 685-686 . denotes .
T26743 686-971 sentence denotes In brain, Rb KO neurons migrate away from the ventricular zone and switch on Tubb3 (βIII-tubulin), but continue to incorporate BrdU [13], and in gut epithelia, differentiated enterocytes migrate up the villi and activate expression of serotonin, yet continue to incorporate BrdU [67].
T26744 687-689 IN denotes In
T26746 690-695 NN denotes brain
T26747 695-697 , denotes ,
T26748 697-699 NN denotes Rb
T26749 700-702 NN denotes KO
T26750 703-710 NNS denotes neurons
T26745 711-718 VBP denotes migrate
T26751 719-723 RB denotes away
T26752 724-728 IN denotes from
T26753 729-732 DT denotes the
T26755 733-744 JJ denotes ventricular
T26754 745-749 NN denotes zone
T26756 750-753 CC denotes and
T26757 754-760 VBP denotes switch
T26758 761-763 RP denotes on
T26759 764-769 NN denotes Tubb3
T26760 770-771 -LRB- denotes (
T26761 771-775 NN denotes βIII
T26763 775-776 HYPH denotes -
T26762 776-783 NN denotes tubulin
T26764 783-784 -RRB- denotes )
T26765 784-786 , denotes ,
T26766 786-789 CC denotes but
T26767 790-798 VBP denotes continue
T26768 799-801 TO denotes to
T26769 802-813 VB denotes incorporate
T26770 814-818 NN denotes BrdU
T26771 819-820 -LRB- denotes [
T26772 820-822 CD denotes 13
T26773 822-823 -RRB- denotes ]
T26774 823-825 , denotes ,
T26775 825-828 CC denotes and
T26776 829-831 IN denotes in
T26778 832-835 NN denotes gut
T26779 836-845 NNS denotes epithelia
T26780 845-847 , denotes ,
T26781 847-861 VBN denotes differentiated
T26782 862-873 NNS denotes enterocytes
T26777 874-881 VBP denotes migrate
T26783 882-884 IN denotes up
T26784 885-888 DT denotes the
T26785 889-894 NNS denotes villi
T26786 895-898 CC denotes and
T26787 899-907 VBP denotes activate
T26788 908-918 NN denotes expression
T26789 919-921 IN denotes of
T26790 922-931 NN denotes serotonin
T26791 931-933 , denotes ,
T26792 933-936 CC denotes yet
T26793 937-945 VBP denotes continue
T26794 946-948 TO denotes to
T26795 949-960 VB denotes incorporate
T26796 961-965 NN denotes BrdU
T26797 966-967 -LRB- denotes [
T26798 967-969 CD denotes 67
T26799 969-970 -RRB- denotes ]
T26800 970-971 . denotes .
T26801 971-1198 sentence denotes In the case of SACs, the differentiation defects we observed (e.g., loss of Slc18a3 and Chat) were not due to aberrant division, but it is possible there are other problems with these cells that are caused by ectopic division.
T26802 972-974 IN denotes In
T26804 975-978 DT denotes the
T26805 979-983 NN denotes case
T26806 984-986 IN denotes of
T26807 987-991 NNS denotes SACs
T26808 991-993 , denotes ,
T26809 993-996 DT denotes the
T26810 997-1012 NN denotes differentiation
T26811 1013-1020 VBZ denotes defects
T26812 1021-1023 PRP denotes we
T26813 1024-1032 VBD denotes observed
T26814 1033-1034 -LRB- denotes (
T26815 1034-1038 FW denotes e.g.
T26817 1038-1040 , denotes ,
T26816 1040-1044 NN denotes loss
T26818 1045-1047 IN denotes of
T26819 1048-1055 NN denotes Slc18a3
T26820 1056-1059 CC denotes and
T26821 1060-1064 NN denotes Chat
T26822 1064-1065 -RRB- denotes )
T26803 1066-1070 VBD denotes were
T26823 1071-1074 RB denotes not
T26824 1075-1078 IN denotes due
T26825 1079-1081 IN denotes to
T26826 1082-1090 JJ denotes aberrant
T26827 1091-1099 NN denotes division
T26828 1099-1101 , denotes ,
T26829 1101-1104 CC denotes but
T26830 1105-1107 PRP denotes it
T26831 1108-1110 VBZ denotes is
T26832 1111-1119 JJ denotes possible
T26833 1120-1125 EX denotes there
T26834 1126-1129 VBP denotes are
T26835 1130-1135 JJ denotes other
T26836 1136-1144 NNS denotes problems
T26837 1145-1149 IN denotes with
T26838 1150-1155 DT denotes these
T26839 1156-1161 NNS denotes cells
T26840 1162-1166 WDT denotes that
T26842 1167-1170 VBP denotes are
T26841 1171-1177 VBN denotes caused
T26843 1178-1180 IN denotes by
T26844 1181-1188 JJ denotes ectopic
T26845 1189-1197 NN denotes division
T26846 1197-1198 . denotes .
T26847 1198-1322 sentence denotes Nevertheless, it is clear that many aspects of differentiation in multiple cell types are compatible with ectopic division.
T26848 1199-1211 RB denotes Nevertheless
T26850 1211-1213 , denotes ,
T26851 1213-1215 PRP denotes it
T26849 1216-1218 VBZ denotes is
T26852 1219-1224 JJ denotes clear
T26853 1225-1229 IN denotes that
T26855 1230-1234 JJ denotes many
T26856 1235-1242 NNS denotes aspects
T26857 1243-1245 IN denotes of
T26858 1246-1261 NN denotes differentiation
T26859 1262-1264 IN denotes in
T26860 1265-1273 JJ denotes multiple
T26862 1274-1278 NN denotes cell
T26861 1279-1284 NNS denotes types
T26854 1285-1288 VBP denotes are
T26863 1289-1299 JJ denotes compatible
T26864 1300-1304 IN denotes with
T26865 1305-1312 JJ denotes ectopic
T26866 1313-1321 NN denotes division
T26867 1321-1322 . denotes .
T26868 1322-1483 sentence denotes However, division of terminally differentiating cells is dangerous, since it may facilitate transformation, as is the case in retinoblastoma (reviewed in [66]).
T26869 1323-1330 RB denotes However
T26871 1330-1332 , denotes ,
T26872 1332-1340 NN denotes division
T26873 1341-1343 IN denotes of
T26874 1344-1354 RB denotes terminally
T26875 1355-1370 VBG denotes differentiating
T26876 1371-1376 NNS denotes cells
T26870 1377-1379 VBZ denotes is
T26877 1380-1389 JJ denotes dangerous
T26878 1389-1391 , denotes ,
T26879 1391-1396 IN denotes since
T26881 1397-1399 PRP denotes it
T26882 1400-1403 MD denotes may
T26880 1404-1414 VB denotes facilitate
T26883 1415-1429 NN denotes transformation
T26884 1429-1431 , denotes ,
T26885 1431-1433 IN denotes as
T26886 1434-1436 VBZ denotes is
T26887 1437-1440 DT denotes the
T26888 1441-1445 NN denotes case
T26889 1446-1448 IN denotes in
T26890 1449-1463 NN denotes retinoblastoma
T26891 1464-1465 -LRB- denotes (
T26892 1465-1473 VBN denotes reviewed
T26893 1474-1476 IN denotes in
T26894 1477-1478 -LRB- denotes [
T26895 1478-1480 CD denotes 66
T26896 1480-1481 -RRB- denotes ]
T26897 1481-1482 -RRB- denotes )
T26898 1482-1483 . denotes .
R7837 T26609 T26610 amod Ectopic,Division
R7838 T26611 T26610 cc and,Division
R7839 T26612 T26610 conj Differentiation,Division
R7840 T26614 T26615 nsubj Rb,is
R7841 T26616 T26615 acomp critical,is
R7842 T26617 T26618 aux to,ensure
R7843 T26618 T26616 xcomp ensure,critical
R7844 T26619 T26620 mark that,leave
R7845 T26620 T26618 ccomp leave,ensure
R7846 T26621 T26622 amod many,types
R7847 T26622 T26620 nsubj types,leave
R7848 T26623 T26622 prep of,types
R7849 T26624 T26625 advmod terminally,differentiating
R7850 T26625 T26626 amod differentiating,cells
R7851 T26626 T26623 pobj cells,of
R7852 T26627 T26628 det the,cycle
R7853 T26628 T26620 dative cycle,leave
R7854 T26629 T26628 compound cell,cycle
R7855 T26630 T26620 punct (,leave
R7856 T26631 T26632 advmod e.g.,neurons
R7857 T26632 T26620 dobj neurons,leave
R7858 T26633 T26632 punct ", ",neurons
R7859 T26634 T26632 punct ", ",neurons
R7860 T26635 T26636 nmod gut,epithelia
R7861 T26636 T26632 conj epithelia,neurons
R7862 T26637 T26635 cc and,gut
R7863 T26638 T26635 conj skin,gut
R7864 T26639 T26636 punct ", ",epithelia
R7865 T26640 T26636 conj muscle,epithelia
R7866 T26641 T26640 punct ", ",muscle
R7867 T26642 T26640 cc and,muscle
R7868 T26643 T26644 compound lens,fibres
R7869 T26644 T26640 conj fibres,muscle
R7870 T26645 T26620 punct ),leave
R7871 T26646 T26647 punct (,reviewed
R7872 T26647 T26620 parataxis reviewed,leave
R7873 T26648 T26647 prep in,reviewed
R7874 T26649 T26648 punct [,in
R7875 T26650 T26648 pobj 66,in
R7876 T26651 T26647 punct ],reviewed
R7877 T26652 T26647 punct ),reviewed
R7878 T26653 T26615 punct .,is
R7879 T26655 T26656 amod Early,studies
R7880 T26656 T26658 nsubj studies,suggested
R7881 T26657 T26656 compound overexpression,studies
R7882 T26659 T26660 advmod in,vitro
R7883 T26660 T26656 advmod vitro,studies
R7884 T26661 T26662 nsubj Rb,temper
R7885 T26662 T26658 advcl temper,suggested
R7886 T26663 T26662 aux might,temper
R7887 T26664 T26662 dobj expansion,temper
R7888 T26665 T26664 prep of,expansion
R7889 T26666 T26667 compound cycling,cells
R7890 T26667 T26665 pobj cells,of
R7891 T26668 T26658 punct ", ",suggested
R7892 T26669 T26658 cc but,suggested
R7893 T26670 T26671 compound KO,studies
R7894 T26671 T26672 nsubj studies,indicate
R7895 T26672 T26658 conj indicate,suggested
R7896 T26673 T26674 advmod in,vivo
R7897 T26674 T26671 advmod vivo,studies
R7898 T26675 T26676 mark that,is
R7899 T26676 T26672 ccomp is,indicate
R7900 T26677 T26678 poss its,role
R7901 T26678 T26676 nsubj role,is
R7902 T26679 T26678 amod major,role
R7903 T26680 T26681 aux to,block
R7904 T26681 T26676 xcomp block,is
R7905 T26682 T26681 dobj division,block
R7906 T26683 T26681 prep in,block
R7907 T26684 T26685 advmod terminally,differentiating
R7908 T26685 T26686 amod differentiating,cells
R7909 T26686 T26683 pobj cells,in
R7910 T26687 T26672 punct .,indicate
R7911 T26689 T26690 prep In,go
R7912 T26691 T26692 poss its,absence
R7913 T26692 T26689 pobj absence,In
R7914 T26693 T26690 punct ", ",go
R7915 T26694 T26690 nsubj many,go
R7916 T26695 T26694 punct (,many
R7917 T26696 T26694 cc but,many
R7918 T26697 T26696 advmod clearly,but
R7919 T26698 T26696 neg not,but
R7920 T26699 T26700 nmod all,aspects
R7921 T26700 T26694 conj aspects,many
R7922 T26701 T26700 punct ),aspects
R7923 T26702 T26694 prep of,many
R7924 T26703 T26702 pobj differentiation,of
R7925 T26704 T26690 prt ahead,go
R7926 T26705 T26706 advmod relatively,unperturbed
R7927 T26706 T26690 advcl unperturbed,go
R7928 T26707 T26690 punct .,go
R7929 T26709 T26710 prep In,born
R7930 T26711 T26712 det the,retina
R7931 T26712 T26709 pobj retina,In
R7932 T26713 T26710 punct ", ",born
R7933 T26714 T26715 amod differentiating,cells
R7934 T26715 T26710 nsubjpass cells,born
R7935 T26716 T26715 compound transition,cells
R7936 T26717 T26710 auxpass are,born
R7937 T26718 T26710 prep in,born
R7938 T26719 T26720 det the,absence
R7939 T26720 T26718 pobj absence,in
R7940 T26721 T26720 prep of,absence
R7941 T26722 T26721 pobj Rb,of
R7942 T26723 T26710 punct ", ",born
R7943 T26724 T26710 conj migrate,born
R7944 T26725 T26724 prep to,migrate
R7945 T26726 T26727 det the,layer
R7946 T26727 T26725 pobj layer,to
R7947 T26728 T26727 amod correct,layer
R7948 T26729 T26724 punct ", ",migrate
R7949 T26730 T26724 cc and,migrate
R7950 T26731 T26724 conj express,migrate
R7951 T26732 T26733 amod appropriate,markers
R7952 T26733 T26731 dobj markers,express
R7953 T26734 T26735 punct (,2
R7954 T26735 T26731 parataxis 2,express
R7955 T26736 T26735 punct [,2
R7956 T26737 T26735 punct ],2
R7957 T26738 T26735 cc and,2
R7958 T26739 T26740 det this,work
R7959 T26740 T26735 conj work,2
R7960 T26741 T26740 punct ),work
R7961 T26742 T26710 punct .,born
R7962 T26744 T26745 prep In,migrate
R7963 T26746 T26744 pobj brain,In
R7964 T26747 T26745 punct ", ",migrate
R7965 T26748 T26749 compound Rb,KO
R7966 T26749 T26750 compound KO,neurons
R7967 T26750 T26745 nsubj neurons,migrate
R7968 T26751 T26745 advmod away,migrate
R7969 T26752 T26751 prep from,away
R7970 T26753 T26754 det the,zone
R7971 T26754 T26752 pobj zone,from
R7972 T26755 T26754 amod ventricular,zone
R7973 T26756 T26745 cc and,migrate
R7974 T26757 T26745 conj switch,migrate
R7975 T26758 T26757 prt on,switch
R7976 T26759 T26757 dobj Tubb3,switch
R7977 T26760 T26759 punct (,Tubb3
R7978 T26761 T26762 compound βIII,tubulin
R7979 T26762 T26759 appos tubulin,Tubb3
R7980 T26763 T26762 punct -,tubulin
R7981 T26764 T26757 punct ),switch
R7982 T26765 T26757 punct ", ",switch
R7983 T26766 T26757 cc but,switch
R7984 T26767 T26757 conj continue,switch
R7985 T26768 T26769 aux to,incorporate
R7986 T26769 T26767 xcomp incorporate,continue
R7987 T26770 T26769 dobj BrdU,incorporate
R7988 T26771 T26772 punct [,13
R7989 T26772 T26769 parataxis 13,incorporate
R7990 T26773 T26772 punct ],13
R7991 T26774 T26745 punct ", ",migrate
R7992 T26775 T26745 cc and,migrate
R7993 T26776 T26777 prep in,migrate
R7994 T26777 T26745 conj migrate,migrate
R7995 T26778 T26779 compound gut,epithelia
R7996 T26779 T26776 pobj epithelia,in
R7997 T26780 T26777 punct ", ",migrate
R7998 T26781 T26782 amod differentiated,enterocytes
R7999 T26782 T26777 nsubj enterocytes,migrate
R8000 T26783 T26777 prep up,migrate
R8001 T26784 T26785 det the,villi
R8002 T26785 T26783 pobj villi,up
R8003 T26786 T26777 cc and,migrate
R8004 T26787 T26777 conj activate,migrate
R8005 T26788 T26787 dobj expression,activate
R8006 T26789 T26788 prep of,expression
R8007 T26790 T26789 pobj serotonin,of
R8008 T26791 T26787 punct ", ",activate
R8009 T26792 T26787 cc yet,activate
R8010 T26793 T26787 conj continue,activate
R8011 T26794 T26795 aux to,incorporate
R8012 T26795 T26793 xcomp incorporate,continue
R8013 T26796 T26795 dobj BrdU,incorporate
R8014 T26797 T26798 punct [,67
R8015 T26798 T26795 parataxis 67,incorporate
R8016 T26799 T26798 punct ],67
R8017 T26800 T26777 punct .,migrate
R8018 T26802 T26803 prep In,were
R8019 T26804 T26805 det the,case
R8020 T26805 T26802 pobj case,In
R8021 T26806 T26805 prep of,case
R8022 T26807 T26806 pobj SACs,of
R8023 T26808 T26803 punct ", ",were
R8024 T26809 T26810 det the,differentiation
R8025 T26810 T26803 nsubj differentiation,were
R8026 T26811 T26810 nmod defects,differentiation
R8027 T26812 T26813 nsubj we,observed
R8028 T26813 T26810 advcl observed,differentiation
R8029 T26814 T26810 punct (,differentiation
R8030 T26815 T26816 advmod e.g.,loss
R8031 T26816 T26810 appos loss,differentiation
R8032 T26817 T26816 punct ", ",loss
R8033 T26818 T26816 prep of,loss
R8034 T26819 T26818 pobj Slc18a3,of
R8035 T26820 T26819 cc and,Slc18a3
R8036 T26821 T26819 conj Chat,Slc18a3
R8037 T26822 T26803 punct ),were
R8038 T26823 T26803 neg not,were
R8039 T26824 T26803 prep due,were
R8040 T26825 T26824 pcomp to,due
R8041 T26826 T26827 amod aberrant,division
R8042 T26827 T26824 pobj division,due
R8043 T26828 T26803 punct ", ",were
R8044 T26829 T26803 cc but,were
R8045 T26830 T26831 nsubj it,is
R8046 T26831 T26803 conj is,were
R8047 T26832 T26831 acomp possible,is
R8048 T26833 T26834 expl there,are
R8049 T26834 T26831 advcl are,is
R8050 T26835 T26836 amod other,problems
R8051 T26836 T26834 attr problems,are
R8052 T26837 T26836 prep with,problems
R8053 T26838 T26839 det these,cells
R8054 T26839 T26837 pobj cells,with
R8055 T26840 T26841 dep that,caused
R8056 T26841 T26836 relcl caused,problems
R8057 T26842 T26841 auxpass are,caused
R8058 T26843 T26841 agent by,caused
R8059 T26844 T26845 amod ectopic,division
R8060 T26845 T26843 pobj division,by
R8061 T26846 T26831 punct .,is
R8062 T26848 T26849 advmod Nevertheless,is
R8063 T26850 T26849 punct ", ",is
R8064 T26851 T26849 nsubj it,is
R8065 T26852 T26849 acomp clear,is
R8066 T26853 T26854 mark that,are
R8067 T26854 T26849 ccomp are,is
R8068 T26855 T26856 amod many,aspects
R8069 T26856 T26854 nsubj aspects,are
R8070 T26857 T26856 prep of,aspects
R8071 T26858 T26857 pobj differentiation,of
R8072 T26859 T26856 prep in,aspects
R8073 T26860 T26861 amod multiple,types
R8074 T26861 T26859 pobj types,in
R8075 T26862 T26861 compound cell,types
R8076 T26863 T26854 acomp compatible,are
R8077 T26864 T26863 prep with,compatible
R8078 T26865 T26866 amod ectopic,division
R8079 T26866 T26864 pobj division,with
R8080 T26867 T26849 punct .,is
R8081 T26869 T26870 advmod However,is
R8082 T26871 T26870 punct ", ",is
R8083 T26872 T26870 nsubj division,is
R8084 T26873 T26872 prep of,division
R8085 T26874 T26875 advmod terminally,differentiating
R8086 T26875 T26876 amod differentiating,cells
R8087 T26876 T26873 pobj cells,of
R8088 T26877 T26870 acomp dangerous,is
R8089 T26878 T26870 punct ", ",is
R8090 T26879 T26880 mark since,facilitate
R8091 T26880 T26870 advcl facilitate,is
R8092 T26881 T26880 nsubj it,facilitate
R8093 T26882 T26880 aux may,facilitate
R8094 T26883 T26880 dobj transformation,facilitate
R8095 T26884 T26880 punct ", ",facilitate
R8096 T26885 T26886 mark as,is
R8097 T26886 T26880 advcl is,facilitate
R8098 T26887 T26888 det the,case
R8099 T26888 T26886 attr case,is
R8100 T26889 T26886 prep in,is
R8101 T26890 T26889 pobj retinoblastoma,in
R8102 T26891 T26892 punct (,reviewed
R8103 T26892 T26886 parataxis reviewed,is
R8104 T26893 T26892 prep in,reviewed
R8105 T26894 T26893 punct [,in
R8106 T26895 T26893 pobj 66,in
R8107 T26896 T26892 punct ],reviewed
R8108 T26897 T26892 punct ),reviewed
R8109 T26898 T26870 punct .,is