Id |
Subject |
Object |
Predicate |
Lexical cue |
T24797 |
0-2 |
NN |
denotes |
Rb |
T38541 |
0-2 |
NN |
denotes |
Rb |
T24796 |
0-6 |
sentence |
denotes |
Rb Reg |
T24798 |
3-5 |
NNS |
denotes |
Re |
T38542 |
3-12 |
VBZ |
denotes |
Regulates |
T24799 |
5-6 |
IN |
denotes |
g |
T24801 |
6-7 |
VBN |
denotes |
u |
T24802 |
7-8 |
JJ |
denotes |
l |
T24803 |
8-9 |
JJ |
denotes |
a |
T38543 |
13-21 |
JJ |
denotes |
Distinct |
T38544 |
22-31 |
NNS |
denotes |
Processes |
T38545 |
32-39 |
IN |
denotes |
through |
T38546 |
40-44 |
NN |
denotes |
E2f1 |
T38547 |
45-48 |
CC |
denotes |
and |
T38548 |
49-54 |
NN |
denotes |
E2f3a |
T38549 |
54-104 |
sentence |
denotes |
Red text and arrows indicate Rb-dependent events. |
T38550 |
55-58 |
JJ |
denotes |
Red |
T38551 |
59-63 |
NN |
denotes |
text |
T38553 |
64-67 |
CC |
denotes |
and |
T38554 |
68-74 |
NNS |
denotes |
arrows |
T38552 |
75-83 |
VBP |
denotes |
indicate |
T38555 |
84-86 |
NN |
denotes |
Rb |
T38557 |
86-87 |
HYPH |
denotes |
- |
T38556 |
87-96 |
JJ |
denotes |
dependent |
T38558 |
97-103 |
NNS |
denotes |
events |
T38559 |
103-104 |
. |
denotes |
. |
T38560 |
104-199 |
sentence |
denotes |
Black text and arrows indicate events for which there is no direct evidence of Rb involvement. |
T38561 |
105-110 |
JJ |
denotes |
Black |
T38562 |
111-115 |
NN |
denotes |
text |
T38564 |
116-119 |
CC |
denotes |
and |
T38565 |
120-126 |
NNS |
denotes |
arrows |
T38563 |
127-135 |
VBP |
denotes |
indicate |
T38566 |
136-142 |
NNS |
denotes |
events |
T38567 |
143-146 |
IN |
denotes |
for |
T38569 |
147-152 |
WDT |
denotes |
which |
T38570 |
153-158 |
EX |
denotes |
there |
T38568 |
159-161 |
VBZ |
denotes |
is |
T38571 |
162-164 |
DT |
denotes |
no |
T38573 |
165-171 |
JJ |
denotes |
direct |
T38572 |
172-180 |
NN |
denotes |
evidence |
T38574 |
181-183 |
IN |
denotes |
of |
T38575 |
184-186 |
NN |
denotes |
Rb |
T38576 |
187-198 |
NN |
denotes |
involvement |
T38577 |
198-199 |
. |
denotes |
. |
T38578 |
199-391 |
sentence |
denotes |
Rb does not appear to temper RPC expansion and is not required for differentiation of RPCs into RTCs, but is essential to couple RTC birth to terminal mitosis, thus locking them out of cycle. |
T38579 |
200-202 |
NN |
denotes |
Rb |
T38581 |
203-207 |
VBZ |
denotes |
does |
T38582 |
208-211 |
RB |
denotes |
not |
T38580 |
212-218 |
VB |
denotes |
appear |
T38583 |
219-221 |
TO |
denotes |
to |
T38584 |
222-228 |
VB |
denotes |
temper |
T38585 |
229-232 |
NN |
denotes |
RPC |
T38586 |
233-242 |
NN |
denotes |
expansion |
T38587 |
243-246 |
CC |
denotes |
and |
T38588 |
247-249 |
VBZ |
denotes |
is |
T38590 |
250-253 |
RB |
denotes |
not |
T38589 |
254-262 |
VBN |
denotes |
required |
T38591 |
263-266 |
IN |
denotes |
for |
T38592 |
267-282 |
NN |
denotes |
differentiation |
T38593 |
283-285 |
IN |
denotes |
of |
T38594 |
286-290 |
NNS |
denotes |
RPCs |
T38595 |
291-295 |
IN |
denotes |
into |
T38596 |
296-300 |
NNS |
denotes |
RTCs |
T38597 |
300-302 |
, |
denotes |
, |
T38598 |
302-305 |
CC |
denotes |
but |
T38599 |
306-308 |
VBZ |
denotes |
is |
T38600 |
309-318 |
JJ |
denotes |
essential |
T38601 |
319-321 |
TO |
denotes |
to |
T38602 |
322-328 |
VB |
denotes |
couple |
T38603 |
329-332 |
NN |
denotes |
RTC |
T38604 |
333-338 |
NN |
denotes |
birth |
T38605 |
339-341 |
IN |
denotes |
to |
T38606 |
342-350 |
JJ |
denotes |
terminal |
T38607 |
351-358 |
NN |
denotes |
mitosis |
T38608 |
358-360 |
, |
denotes |
, |
T38609 |
360-364 |
RB |
denotes |
thus |
T38610 |
365-372 |
VBG |
denotes |
locking |
T38611 |
373-377 |
PRP |
denotes |
them |
T38612 |
378-381 |
RB |
denotes |
out |
T38613 |
382-384 |
IN |
denotes |
of |
T38614 |
385-390 |
NN |
denotes |
cycle |
T38615 |
390-391 |
. |
denotes |
. |
T38616 |
391-437 |
sentence |
denotes |
Rb performs this function by inhibiting E2f1. |
T38617 |
392-394 |
NN |
denotes |
Rb |
T38618 |
395-403 |
VBZ |
denotes |
performs |
T38619 |
404-408 |
DT |
denotes |
this |
T38620 |
409-417 |
NN |
denotes |
function |
T38621 |
418-420 |
IN |
denotes |
by |
T38622 |
421-431 |
VBG |
denotes |
inhibiting |
T38623 |
432-436 |
NN |
denotes |
E2f1 |
T38624 |
436-437 |
. |
denotes |
. |
T38625 |
437-526 |
sentence |
denotes |
Rb is also required for SAC differentiation, and in this case, acts by inhibiting E2f3a. |
T38626 |
438-440 |
NN |
denotes |
Rb |
T38628 |
441-443 |
VBZ |
denotes |
is |
T38629 |
444-448 |
RB |
denotes |
also |
T38627 |
449-457 |
VBN |
denotes |
required |
T38630 |
458-461 |
IN |
denotes |
for |
T38631 |
462-465 |
NN |
denotes |
SAC |
T38632 |
466-481 |
NN |
denotes |
differentiation |
T38633 |
481-483 |
, |
denotes |
, |
T38634 |
483-486 |
CC |
denotes |
and |
T38635 |
487-489 |
IN |
denotes |
in |
T38637 |
490-494 |
DT |
denotes |
this |
T38638 |
495-499 |
NN |
denotes |
case |
T38639 |
499-501 |
, |
denotes |
, |
T38636 |
501-505 |
VBZ |
denotes |
acts |
T38640 |
506-508 |
IN |
denotes |
by |
T38641 |
509-519 |
VBG |
denotes |
inhibiting |
T38642 |
520-525 |
NN |
denotes |
E2f3a |
T38643 |
525-526 |
. |
denotes |
. |
T38644 |
526-624 |
sentence |
denotes |
There is no direct evidence that Rb is required for terminal differentiation of other cell types. |
T38645 |
527-532 |
EX |
denotes |
There |
T38646 |
533-535 |
VBZ |
denotes |
is |
T38647 |
536-538 |
DT |
denotes |
no |
T38649 |
539-545 |
JJ |
denotes |
direct |
T38648 |
546-554 |
NN |
denotes |
evidence |
T38650 |
555-559 |
IN |
denotes |
that |
T38652 |
560-562 |
NN |
denotes |
Rb |
T38653 |
563-565 |
VBZ |
denotes |
is |
T38651 |
566-574 |
VBN |
denotes |
required |
T38654 |
575-578 |
IN |
denotes |
for |
T38655 |
579-587 |
JJ |
denotes |
terminal |
T38656 |
588-603 |
NN |
denotes |
differentiation |
T38657 |
604-606 |
IN |
denotes |
of |
T38658 |
607-612 |
JJ |
denotes |
other |
T38660 |
613-617 |
NN |
denotes |
cell |
T38659 |
618-623 |
NNS |
denotes |
types |
T38661 |
623-624 |
. |
denotes |
. |
T38662 |
624-672 |
sentence |
denotes |
Colour codes and abbreviations as in Figure 1A. |
T38663 |
625-631 |
NN |
denotes |
Colour |
T38664 |
632-637 |
NNS |
denotes |
codes |
T38665 |
638-641 |
CC |
denotes |
and |
T38666 |
642-655 |
NNS |
denotes |
abbreviations |
T38667 |
656-658 |
IN |
denotes |
as |
T38668 |
659-661 |
IN |
denotes |
in |
T38669 |
662-668 |
NN |
denotes |
Figure |
T38670 |
669-671 |
NN |
denotes |
1A |
T38671 |
671-672 |
. |
denotes |
. |
R11654 |
T38541 |
T38542 |
nsubj |
Rb,Regulates |
R11655 |
T38543 |
T38544 |
amod |
Distinct,Processes |
R11656 |
T38544 |
T38542 |
dobj |
Processes,Regulates |
R11657 |
T38545 |
T38542 |
prep |
through,Regulates |
R11658 |
T38546 |
T38545 |
pobj |
E2f1,through |
R11659 |
T38547 |
T38546 |
cc |
and,E2f1 |
R11660 |
T38548 |
T38546 |
conj |
E2f3a,E2f1 |
R11661 |
T38550 |
T38551 |
amod |
Red,text |
R11662 |
T38551 |
T38552 |
nsubj |
text,indicate |
R11663 |
T38553 |
T38551 |
cc |
and,text |
R11664 |
T38554 |
T38551 |
conj |
arrows,text |
R11665 |
T38555 |
T38556 |
npadvmod |
Rb,dependent |
R11666 |
T38556 |
T38558 |
amod |
dependent,events |
R11667 |
T38557 |
T38556 |
punct |
-,dependent |
R11668 |
T38558 |
T38552 |
dobj |
events,indicate |
R11669 |
T38559 |
T38552 |
punct |
.,indicate |
R11670 |
T38561 |
T38562 |
amod |
Black,text |
R11671 |
T38562 |
T38563 |
nsubj |
text,indicate |
R11672 |
T38564 |
T38562 |
cc |
and,text |
R11673 |
T38565 |
T38562 |
conj |
arrows,text |
R11674 |
T38566 |
T38563 |
dobj |
events,indicate |
R11675 |
T38567 |
T38568 |
prep |
for,is |
R11676 |
T38568 |
T38566 |
relcl |
is,events |
R11677 |
T38569 |
T38567 |
pobj |
which,for |
R11678 |
T38570 |
T38568 |
expl |
there,is |
R11679 |
T38571 |
T38572 |
det |
no,evidence |
R11680 |
T38572 |
T38568 |
attr |
evidence,is |
R11681 |
T38573 |
T38572 |
amod |
direct,evidence |
R11682 |
T38574 |
T38572 |
prep |
of,evidence |
R11683 |
T38575 |
T38576 |
compound |
Rb,involvement |
R11684 |
T38576 |
T38574 |
pobj |
involvement,of |
R11685 |
T38577 |
T38563 |
punct |
.,indicate |
R11686 |
T38579 |
T38580 |
nsubj |
Rb,appear |
R11687 |
T38581 |
T38580 |
aux |
does,appear |
R11688 |
T38582 |
T38580 |
neg |
not,appear |
R11689 |
T38583 |
T38584 |
aux |
to,temper |
R11690 |
T38584 |
T38580 |
xcomp |
temper,appear |
R11691 |
T38585 |
T38586 |
compound |
RPC,expansion |
R11692 |
T38586 |
T38584 |
dobj |
expansion,temper |
R11693 |
T38587 |
T38580 |
cc |
and,appear |
R11694 |
T38588 |
T38589 |
auxpass |
is,required |
R11695 |
T38589 |
T38580 |
conj |
required,appear |
R11696 |
T38590 |
T38589 |
neg |
not,required |
R11697 |
T38591 |
T38589 |
prep |
for,required |
R11698 |
T38592 |
T38591 |
pobj |
differentiation,for |
R11699 |
T38593 |
T38592 |
prep |
of,differentiation |
R11700 |
T38594 |
T38593 |
pobj |
RPCs,of |
R11701 |
T38595 |
T38592 |
prep |
into,differentiation |
R11702 |
T38596 |
T38595 |
pobj |
RTCs,into |
R11703 |
T38597 |
T38589 |
punct |
", ",required |
R11704 |
T38598 |
T38589 |
cc |
but,required |
R11705 |
T38599 |
T38589 |
conj |
is,required |
R11706 |
T38600 |
T38599 |
acomp |
essential,is |
R11707 |
T38601 |
T38602 |
aux |
to,couple |
R11708 |
T38602 |
T38599 |
advcl |
couple,is |
R11709 |
T38603 |
T38604 |
compound |
RTC,birth |
R11710 |
T38604 |
T38602 |
dobj |
birth,couple |
R11711 |
T38605 |
T38602 |
prep |
to,couple |
R11712 |
T38606 |
T38607 |
amod |
terminal,mitosis |
R11713 |
T38607 |
T38605 |
pobj |
mitosis,to |
R11714 |
T38608 |
T38602 |
punct |
", ",couple |
R11715 |
T38609 |
T38610 |
advmod |
thus,locking |
R11716 |
T38610 |
T38602 |
advcl |
locking,couple |
R11717 |
T38611 |
T38610 |
dobj |
them,locking |
R11718 |
T38612 |
T38613 |
advmod |
out,of |
R11719 |
T38613 |
T38610 |
oprd |
of,locking |
R11720 |
T38614 |
T38613 |
pobj |
cycle,of |
R11721 |
T38615 |
T38580 |
punct |
.,appear |
R11722 |
T38617 |
T38618 |
nsubj |
Rb,performs |
R11723 |
T38619 |
T38620 |
det |
this,function |
R11724 |
T38620 |
T38618 |
dobj |
function,performs |
R11725 |
T38621 |
T38618 |
prep |
by,performs |
R11726 |
T38622 |
T38621 |
pcomp |
inhibiting,by |
R11727 |
T38623 |
T38622 |
dobj |
E2f1,inhibiting |
R11728 |
T38624 |
T38618 |
punct |
.,performs |
R11729 |
T38626 |
T38627 |
nsubjpass |
Rb,required |
R11730 |
T38628 |
T38627 |
auxpass |
is,required |
R11731 |
T38629 |
T38627 |
advmod |
also,required |
R11732 |
T38630 |
T38627 |
prep |
for,required |
R11733 |
T38631 |
T38632 |
compound |
SAC,differentiation |
R11734 |
T38632 |
T38630 |
pobj |
differentiation,for |
R11735 |
T38633 |
T38627 |
punct |
", ",required |
R11736 |
T38634 |
T38627 |
cc |
and,required |
R11737 |
T38635 |
T38636 |
prep |
in,acts |
R11738 |
T38636 |
T38627 |
conj |
acts,required |
R11739 |
T38637 |
T38638 |
det |
this,case |
R11740 |
T38638 |
T38635 |
pobj |
case,in |
R11741 |
T38639 |
T38636 |
punct |
", ",acts |
R11742 |
T38640 |
T38636 |
prep |
by,acts |
R11743 |
T38641 |
T38640 |
pcomp |
inhibiting,by |
R11744 |
T38642 |
T38641 |
dobj |
E2f3a,inhibiting |
R11745 |
T38643 |
T38627 |
punct |
.,required |
R11746 |
T38645 |
T38646 |
expl |
There,is |
R11747 |
T38647 |
T38648 |
det |
no,evidence |
R11748 |
T38648 |
T38646 |
attr |
evidence,is |
R11749 |
T38649 |
T38648 |
amod |
direct,evidence |
R11750 |
T38650 |
T38651 |
mark |
that,required |
R11751 |
T38651 |
T38648 |
acl |
required,evidence |
R11752 |
T38652 |
T38651 |
nsubjpass |
Rb,required |
R11753 |
T38653 |
T38651 |
auxpass |
is,required |
R11754 |
T38654 |
T38651 |
prep |
for,required |
R11755 |
T38655 |
T38656 |
amod |
terminal,differentiation |
R11756 |
T38656 |
T38654 |
pobj |
differentiation,for |
R11757 |
T38657 |
T38656 |
prep |
of,differentiation |
R11758 |
T38658 |
T38659 |
amod |
other,types |
R11759 |
T38659 |
T38657 |
pobj |
types,of |
R11760 |
T38660 |
T38659 |
compound |
cell,types |
R11761 |
T38661 |
T38646 |
punct |
.,is |
R11762 |
T38663 |
T38664 |
compound |
Colour,codes |
R11763 |
T38665 |
T38664 |
cc |
and,codes |
R11764 |
T38666 |
T38664 |
conj |
abbreviations,codes |
R11765 |
T38667 |
T38664 |
prep |
as,codes |
R11766 |
T38668 |
T38667 |
prep |
in,as |
R11767 |
T38669 |
T38670 |
compound |
Figure,1A |
R11768 |
T38670 |
T38668 |
pobj |
1A,in |
R11769 |
T38671 |
T38664 |
punct |
.,codes |