Id |
Subject |
Object |
Predicate |
Lexical cue |
T37915 |
0-3 |
DT |
denotes |
The |
T37917 |
4-9 |
NN |
denotes |
E2f3a |
T37916 |
10-17 |
NN |
denotes |
Isoform |
T37918 |
18-24 |
VBZ |
denotes |
Drives |
T37919 |
25-28 |
DT |
denotes |
the |
T37921 |
29-44 |
NN |
denotes |
Differentiation |
T37920 |
45-51 |
NN |
denotes |
Defect |
T37922 |
52-54 |
IN |
denotes |
in |
T37923 |
55-57 |
NN |
denotes |
Rb |
T37924 |
58-60 |
NN |
denotes |
KO |
T37925 |
61-65 |
NNS |
denotes |
SACs |
T37926 |
65-199 |
sentence |
denotes |
(A) Schematic diagrams of the mouse WT, E2f3a−/−, and the Cre-recombined floxed E2f3 loci (indicated here as E2f3−/− for simplicity). |
T37927 |
66-67 |
-LRB- |
denotes |
( |
T37928 |
67-68 |
LS |
denotes |
A |
T37930 |
68-69 |
-RRB- |
denotes |
) |
T37931 |
70-79 |
JJ |
denotes |
Schematic |
T37929 |
80-88 |
NNS |
denotes |
diagrams |
T37932 |
89-91 |
IN |
denotes |
of |
T37933 |
92-95 |
DT |
denotes |
the |
T37935 |
96-101 |
NN |
denotes |
mouse |
T37934 |
102-104 |
NN |
denotes |
WT |
T37936 |
104-106 |
, |
denotes |
, |
T37937 |
106-111 |
NN |
denotes |
E2f3a |
T37938 |
111-112 |
SYM |
denotes |
− |
T37939 |
112-113 |
HYPH |
denotes |
/ |
T37940 |
113-114 |
SYM |
denotes |
− |
T37941 |
114-116 |
, |
denotes |
, |
T37942 |
116-119 |
CC |
denotes |
and |
T37943 |
120-123 |
DT |
denotes |
the |
T37945 |
124-127 |
NN |
denotes |
Cre |
T37946 |
127-128 |
HYPH |
denotes |
- |
T37947 |
128-138 |
VBN |
denotes |
recombined |
T37948 |
139-145 |
VBN |
denotes |
floxed |
T37949 |
146-150 |
NN |
denotes |
E2f3 |
T37944 |
151-155 |
NNS |
denotes |
loci |
T37950 |
156-157 |
-LRB- |
denotes |
( |
T37951 |
157-166 |
VBN |
denotes |
indicated |
T37952 |
167-171 |
RB |
denotes |
here |
T37953 |
172-174 |
IN |
denotes |
as |
T37954 |
175-179 |
NN |
denotes |
E2f3 |
T37955 |
179-180 |
SYM |
denotes |
− |
T37956 |
180-181 |
HYPH |
denotes |
/ |
T37957 |
181-182 |
SYM |
denotes |
− |
T37958 |
183-186 |
IN |
denotes |
for |
T37959 |
187-197 |
NN |
denotes |
simplicity |
T37960 |
197-198 |
-RRB- |
denotes |
) |
T37961 |
198-199 |
. |
denotes |
. |
T37962 |
199-279 |
sentence |
denotes |
E2f3a−/− mice lack most of E2f3 exon 1a and part of intron 1a (red dotted box). |
T37963 |
200-205 |
NN |
denotes |
E2f3a |
T37965 |
205-206 |
SYM |
denotes |
− |
T37966 |
206-207 |
HYPH |
denotes |
/ |
T37967 |
207-208 |
SYM |
denotes |
− |
T37964 |
209-213 |
NNS |
denotes |
mice |
T37968 |
214-218 |
VBP |
denotes |
lack |
T37969 |
219-223 |
JJS |
denotes |
most |
T37970 |
224-226 |
IN |
denotes |
of |
T37971 |
227-231 |
NN |
denotes |
E2f3 |
T37973 |
232-236 |
NN |
denotes |
exon |
T37972 |
237-239 |
NN |
denotes |
1a |
T37974 |
240-243 |
CC |
denotes |
and |
T37975 |
244-248 |
NN |
denotes |
part |
T37976 |
249-251 |
IN |
denotes |
of |
T37977 |
252-258 |
NN |
denotes |
intron |
T37978 |
259-261 |
NN |
denotes |
1a |
T37979 |
262-263 |
-LRB- |
denotes |
( |
T37981 |
263-266 |
JJ |
denotes |
red |
T37982 |
267-273 |
VBN |
denotes |
dotted |
T37980 |
274-277 |
NN |
denotes |
box |
T37983 |
277-278 |
-RRB- |
denotes |
) |
T37984 |
278-279 |
. |
denotes |
. |
T37985 |
279-308 |
sentence |
denotes |
Arrows indicate PCR primers. |
T37986 |
280-286 |
NNS |
denotes |
Arrows |
T37987 |
287-295 |
VBP |
denotes |
indicate |
T37988 |
296-299 |
NN |
denotes |
PCR |
T37989 |
300-307 |
NNS |
denotes |
primers |
T37990 |
307-308 |
. |
denotes |
. |
T37991 |
308-363 |
sentence |
denotes |
Genotyping of an E2f3a+/− mouse is shown on the right. |
T37992 |
309-319 |
NN |
denotes |
Genotyping |
T37994 |
320-322 |
IN |
denotes |
of |
T37995 |
323-325 |
DT |
denotes |
an |
T37997 |
326-331 |
NN |
denotes |
E2f3a |
T37998 |
331-332 |
SYM |
denotes |
+ |
T37999 |
332-333 |
HYPH |
denotes |
/ |
T38000 |
333-334 |
SYM |
denotes |
− |
T37996 |
335-340 |
NN |
denotes |
mouse |
T38001 |
341-343 |
VBZ |
denotes |
is |
T37993 |
344-349 |
VBN |
denotes |
shown |
T38002 |
350-352 |
IN |
denotes |
on |
T38003 |
353-356 |
DT |
denotes |
the |
T38004 |
357-362 |
NN |
denotes |
right |
T38005 |
362-363 |
. |
denotes |
. |
T38006 |
363-423 |
sentence |
denotes |
(B) RT-PCR detection of E2f3a and E2f3b mRNA in the retina. |
T38007 |
364-365 |
-LRB- |
denotes |
( |
T38008 |
365-366 |
LS |
denotes |
B |
T38010 |
366-367 |
-RRB- |
denotes |
) |
T38011 |
368-370 |
NN |
denotes |
RT |
T38013 |
370-371 |
HYPH |
denotes |
- |
T38012 |
371-374 |
NN |
denotes |
PCR |
T38009 |
375-384 |
NN |
denotes |
detection |
T38014 |
385-387 |
IN |
denotes |
of |
T38015 |
388-393 |
NN |
denotes |
E2f3a |
T38017 |
394-397 |
CC |
denotes |
and |
T38018 |
398-403 |
NN |
denotes |
E2f3b |
T38016 |
404-408 |
NN |
denotes |
mRNA |
T38019 |
409-411 |
IN |
denotes |
in |
T38020 |
412-415 |
DT |
denotes |
the |
T38021 |
416-422 |
NN |
denotes |
retina |
T38022 |
422-423 |
. |
denotes |
. |
T38023 |
423-557 |
sentence |
denotes |
The sequences of primers are 1aF (5′-GCCTCTACACCACGCCACAAG-3′), 1bF (5′-CGGAAATGCCCTTACAGC-3′), and 4R (5′-CTCAGTCACTTCTTTGGACAG-3′). |
T38024 |
424-427 |
DT |
denotes |
The |
T38025 |
428-437 |
NNS |
denotes |
sequences |
T38027 |
438-440 |
IN |
denotes |
of |
T38028 |
441-448 |
NNS |
denotes |
primers |
T38026 |
449-452 |
VBP |
denotes |
are |
T38029 |
453-456 |
NN |
denotes |
1aF |
T38030 |
457-458 |
-LRB- |
denotes |
( |
T38031 |
458-459 |
CD |
denotes |
5 |
T38033 |
459-460 |
SYM |
denotes |
′ |
T38034 |
460-461 |
HYPH |
denotes |
- |
T38032 |
461-482 |
NN |
denotes |
GCCTCTACACCACGCCACAAG |
T38035 |
482-483 |
HYPH |
denotes |
- |
T38036 |
483-484 |
CD |
denotes |
3 |
T38037 |
484-485 |
SYM |
denotes |
′ |
T38038 |
485-486 |
-RRB- |
denotes |
) |
T38039 |
486-488 |
, |
denotes |
, |
T38040 |
488-491 |
NN |
denotes |
1bF |
T38041 |
492-493 |
-LRB- |
denotes |
( |
T38042 |
493-494 |
CD |
denotes |
5 |
T38044 |
494-495 |
SYM |
denotes |
′ |
T38045 |
495-496 |
HYPH |
denotes |
- |
T38043 |
496-514 |
NN |
denotes |
CGGAAATGCCCTTACAGC |
T38046 |
514-515 |
HYPH |
denotes |
- |
T38047 |
515-516 |
CD |
denotes |
3 |
T38048 |
516-517 |
SYM |
denotes |
′ |
T38049 |
517-518 |
-RRB- |
denotes |
) |
T38050 |
518-520 |
, |
denotes |
, |
T38051 |
520-523 |
CC |
denotes |
and |
T38052 |
524-526 |
NN |
denotes |
4R |
T38053 |
527-528 |
-LRB- |
denotes |
( |
T38054 |
528-529 |
CD |
denotes |
5 |
T38056 |
529-530 |
SYM |
denotes |
′ |
T38057 |
530-531 |
HYPH |
denotes |
- |
T38055 |
531-552 |
NN |
denotes |
CTCAGTCACTTCTTTGGACAG |
T38058 |
552-553 |
HYPH |
denotes |
- |
T38059 |
553-554 |
CD |
denotes |
3 |
T38060 |
554-555 |
SYM |
denotes |
′ |
T38061 |
555-556 |
-RRB- |
denotes |
) |
T38062 |
556-557 |
. |
denotes |
. |
T38063 |
557-604 |
sentence |
denotes |
WT retina expresses both E2f3a and E2f3b mRNA. |
T38064 |
558-560 |
NN |
denotes |
WT |
T38065 |
561-567 |
NN |
denotes |
retina |
T38066 |
568-577 |
VBZ |
denotes |
expresses |
T38067 |
578-582 |
CC |
denotes |
both |
T38068 |
583-588 |
NN |
denotes |
E2f3a |
T38070 |
589-592 |
CC |
denotes |
and |
T38071 |
593-598 |
NN |
denotes |
E2f3b |
T38069 |
599-603 |
NN |
denotes |
mRNA |
T38072 |
603-604 |
. |
denotes |
. |
T38073 |
604-682 |
sentence |
denotes |
As expected, E2f3a−/− retina lacks E2f3a mRNA and still expresses E2f3b mRNA. |
T38074 |
605-607 |
IN |
denotes |
As |
T38075 |
608-616 |
VBN |
denotes |
expected |
T38077 |
616-618 |
, |
denotes |
, |
T38078 |
618-623 |
NN |
denotes |
E2f3a |
T38080 |
623-624 |
SYM |
denotes |
− |
T38081 |
624-625 |
HYPH |
denotes |
/ |
T38082 |
625-626 |
SYM |
denotes |
− |
T38079 |
627-633 |
NN |
denotes |
retina |
T38076 |
634-639 |
VBZ |
denotes |
lacks |
T38083 |
640-645 |
NN |
denotes |
E2f3a |
T38084 |
646-650 |
NN |
denotes |
mRNA |
T38085 |
651-654 |
CC |
denotes |
and |
T38086 |
655-660 |
RB |
denotes |
still |
T38087 |
661-670 |
VBZ |
denotes |
expresses |
T38088 |
671-676 |
NN |
denotes |
E2f3b |
T38089 |
677-681 |
NN |
denotes |
mRNA |
T38090 |
681-682 |
. |
denotes |
. |
T38091 |
682-793 |
sentence |
denotes |
E2f3−/− retina lacks full-length E2f3a and E2f3b mRNAs, and instead expresses a truncated mRNA lacking exon 3. |
T38092 |
683-687 |
NN |
denotes |
E2f3 |
T38094 |
687-688 |
SYM |
denotes |
− |
T38095 |
688-689 |
HYPH |
denotes |
/ |
T38096 |
689-690 |
SYM |
denotes |
− |
T38093 |
691-697 |
NN |
denotes |
retina |
T38097 |
698-703 |
VBZ |
denotes |
lacks |
T38098 |
704-708 |
JJ |
denotes |
full |
T38100 |
708-709 |
HYPH |
denotes |
- |
T38099 |
709-715 |
NN |
denotes |
length |
T38102 |
716-721 |
NN |
denotes |
E2f3a |
T38103 |
722-725 |
CC |
denotes |
and |
T38104 |
726-731 |
NN |
denotes |
E2f3b |
T38101 |
732-737 |
NNS |
denotes |
mRNAs |
T38105 |
737-739 |
, |
denotes |
, |
T38106 |
739-742 |
CC |
denotes |
and |
T38107 |
743-750 |
RB |
denotes |
instead |
T38108 |
751-760 |
VBZ |
denotes |
expresses |
T38109 |
761-762 |
DT |
denotes |
a |
T38111 |
763-772 |
VBN |
denotes |
truncated |
T38110 |
773-777 |
NN |
denotes |
mRNA |
T38112 |
778-785 |
VBG |
denotes |
lacking |
T38113 |
786-790 |
NN |
denotes |
exon |
T38114 |
791-792 |
CD |
denotes |
3 |
T38115 |
792-793 |
. |
denotes |
. |
T38116 |
793-878 |
sentence |
denotes |
(C) Real-time RT-PCR analysis of E2f genes in P8 retinas of the indicated genotypes. |
T38117 |
794-795 |
-LRB- |
denotes |
( |
T38118 |
795-796 |
LS |
denotes |
C |
T38120 |
796-797 |
-RRB- |
denotes |
) |
T38121 |
798-802 |
JJ |
denotes |
Real |
T38123 |
802-803 |
HYPH |
denotes |
- |
T38122 |
803-807 |
NN |
denotes |
time |
T38124 |
808-810 |
NN |
denotes |
RT |
T38126 |
810-811 |
HYPH |
denotes |
- |
T38125 |
811-814 |
NN |
denotes |
PCR |
T38119 |
815-823 |
NN |
denotes |
analysis |
T38127 |
824-826 |
IN |
denotes |
of |
T38128 |
827-830 |
NN |
denotes |
E2f |
T38129 |
831-836 |
NNS |
denotes |
genes |
T38130 |
837-839 |
IN |
denotes |
in |
T38131 |
840-842 |
NN |
denotes |
P8 |
T38132 |
843-850 |
NNS |
denotes |
retinas |
T38133 |
851-853 |
IN |
denotes |
of |
T38134 |
854-857 |
DT |
denotes |
the |
T38136 |
858-867 |
VBN |
denotes |
indicated |
T38135 |
868-877 |
NNS |
denotes |
genotypes |
T38137 |
877-878 |
. |
denotes |
. |
T38138 |
878-1078 |
sentence |
denotes |
Error bars represent SD of measurements from three animals, and asterisks indicate a significant difference between WT and the indicated genotypes (*, p <0.05; **; p <0.01; ANOVA and Tukey HSD test). |
T38139 |
879-884 |
NN |
denotes |
Error |
T38140 |
885-889 |
NNS |
denotes |
bars |
T38141 |
890-899 |
VBP |
denotes |
represent |
T38142 |
900-902 |
NN |
denotes |
SD |
T38143 |
903-905 |
IN |
denotes |
of |
T38144 |
906-918 |
NNS |
denotes |
measurements |
T38145 |
919-923 |
IN |
denotes |
from |
T38146 |
924-929 |
CD |
denotes |
three |
T38147 |
930-937 |
NNS |
denotes |
animals |
T38148 |
937-939 |
, |
denotes |
, |
T38149 |
939-942 |
CC |
denotes |
and |
T38150 |
943-952 |
NNS |
denotes |
asterisks |
T38151 |
953-961 |
VBP |
denotes |
indicate |
T38152 |
962-963 |
DT |
denotes |
a |
T38154 |
964-975 |
JJ |
denotes |
significant |
T38153 |
976-986 |
NN |
denotes |
difference |
T38155 |
987-994 |
IN |
denotes |
between |
T38156 |
995-997 |
NN |
denotes |
WT |
T38157 |
998-1001 |
CC |
denotes |
and |
T38158 |
1002-1005 |
DT |
denotes |
the |
T38159 |
1006-1015 |
VBN |
denotes |
indicated |
T38160 |
1016-1025 |
NNS |
denotes |
genotypes |
T38161 |
1026-1027 |
-LRB- |
denotes |
( |
T38163 |
1027-1028 |
SYM |
denotes |
* |
T38165 |
1028-1030 |
, |
denotes |
, |
T38166 |
1030-1031 |
NN |
denotes |
p |
T38167 |
1032-1033 |
SYM |
denotes |
< |
T38164 |
1033-1037 |
CD |
denotes |
0.05 |
T38168 |
1037-1038 |
: |
denotes |
; |
T38169 |
1039-1041 |
SYM |
denotes |
** |
T38171 |
1041-1042 |
: |
denotes |
; |
T38172 |
1043-1044 |
NN |
denotes |
p |
T38173 |
1045-1046 |
SYM |
denotes |
< |
T38170 |
1046-1050 |
CD |
denotes |
0.01 |
T38174 |
1050-1051 |
: |
denotes |
; |
T38175 |
1052-1057 |
NN |
denotes |
ANOVA |
T38176 |
1058-1061 |
CC |
denotes |
and |
T38177 |
1062-1067 |
NNP |
denotes |
Tukey |
T38178 |
1068-1071 |
NN |
denotes |
HSD |
T38162 |
1072-1076 |
NN |
denotes |
test |
T38179 |
1076-1077 |
-RRB- |
denotes |
) |
T38180 |
1077-1078 |
. |
denotes |
. |
T38181 |
1078-1122 |
sentence |
denotes |
(D) Rescue of Rb KO SACs by E2f3a deletion. |
T38182 |
1079-1080 |
-LRB- |
denotes |
( |
T38183 |
1080-1081 |
LS |
denotes |
D |
T38185 |
1081-1082 |
-RRB- |
denotes |
) |
T38184 |
1083-1089 |
NN |
denotes |
Rescue |
T38186 |
1090-1092 |
IN |
denotes |
of |
T38187 |
1093-1095 |
NN |
denotes |
Rb |
T38188 |
1096-1098 |
NN |
denotes |
KO |
T38189 |
1099-1103 |
NNS |
denotes |
SACs |
T38190 |
1104-1106 |
IN |
denotes |
by |
T38191 |
1107-1112 |
NN |
denotes |
E2f3a |
T38192 |
1113-1121 |
NN |
denotes |
deletion |
T38193 |
1121-1122 |
. |
denotes |
. |
T38194 |
1122-1280 |
sentence |
denotes |
Horizontal retinal sections of the indicated genotypes and ages were stained for nuclei (DAPI, blue), M-phase (PH3, green), and the SAC marker Slc18a3 (red). |
T38195 |
1123-1133 |
JJ |
denotes |
Horizontal |
T38197 |
1134-1141 |
JJ |
denotes |
retinal |
T38196 |
1142-1150 |
NNS |
denotes |
sections |
T38199 |
1151-1153 |
IN |
denotes |
of |
T38200 |
1154-1157 |
DT |
denotes |
the |
T38202 |
1158-1167 |
VBN |
denotes |
indicated |
T38201 |
1168-1177 |
NNS |
denotes |
genotypes |
T38203 |
1178-1181 |
CC |
denotes |
and |
T38204 |
1182-1186 |
NNS |
denotes |
ages |
T38205 |
1187-1191 |
VBD |
denotes |
were |
T38198 |
1192-1199 |
VBN |
denotes |
stained |
T38206 |
1200-1203 |
IN |
denotes |
for |
T38207 |
1204-1210 |
NNS |
denotes |
nuclei |
T38208 |
1211-1212 |
-LRB- |
denotes |
( |
T38210 |
1212-1216 |
NN |
denotes |
DAPI |
T38211 |
1216-1218 |
, |
denotes |
, |
T38209 |
1218-1222 |
JJ |
denotes |
blue |
T38212 |
1222-1223 |
-RRB- |
denotes |
) |
T38213 |
1223-1225 |
, |
denotes |
, |
T38214 |
1225-1226 |
NN |
denotes |
M |
T38216 |
1226-1227 |
HYPH |
denotes |
- |
T38215 |
1227-1232 |
NN |
denotes |
phase |
T38217 |
1233-1234 |
-LRB- |
denotes |
( |
T38219 |
1234-1237 |
NN |
denotes |
PH3 |
T38220 |
1237-1239 |
, |
denotes |
, |
T38218 |
1239-1244 |
JJ |
denotes |
green |
T38221 |
1244-1245 |
-RRB- |
denotes |
) |
T38222 |
1245-1247 |
, |
denotes |
, |
T38223 |
1247-1250 |
CC |
denotes |
and |
T38224 |
1251-1254 |
DT |
denotes |
the |
T38226 |
1255-1258 |
NN |
denotes |
SAC |
T38225 |
1259-1265 |
NN |
denotes |
marker |
T38227 |
1266-1273 |
NN |
denotes |
Slc18a3 |
T38228 |
1274-1275 |
-LRB- |
denotes |
( |
T38229 |
1275-1278 |
JJ |
denotes |
red |
T38230 |
1278-1279 |
-RRB- |
denotes |
) |
T38231 |
1279-1280 |
. |
denotes |
. |
T38232 |
1280-1359 |
sentence |
denotes |
E2f3a deletion does not suppress ectopic division, but rescues the SAC defect. |
T38233 |
1281-1286 |
NN |
denotes |
E2f3a |
T38234 |
1287-1295 |
NN |
denotes |
deletion |
T38236 |
1296-1300 |
VBZ |
denotes |
does |
T38237 |
1301-1304 |
RB |
denotes |
not |
T38235 |
1305-1313 |
VB |
denotes |
suppress |
T38238 |
1314-1321 |
JJ |
denotes |
ectopic |
T38239 |
1322-1330 |
NN |
denotes |
division |
T38240 |
1330-1332 |
, |
denotes |
, |
T38241 |
1332-1335 |
CC |
denotes |
but |
T38242 |
1336-1343 |
VBZ |
denotes |
rescues |
T38243 |
1344-1347 |
DT |
denotes |
the |
T38245 |
1348-1351 |
NN |
denotes |
SAC |
T38244 |
1352-1358 |
NN |
denotes |
defect |
T38246 |
1358-1359 |
. |
denotes |
. |
T38247 |
1359-1381 |
sentence |
denotes |
Scale bars are 50 μm. |
T38248 |
1360-1365 |
NN |
denotes |
Scale |
T38249 |
1366-1370 |
NNS |
denotes |
bars |
T38250 |
1371-1374 |
VBP |
denotes |
are |
T38251 |
1375-1377 |
CD |
denotes |
50 |
T38252 |
1378-1380 |
NN |
denotes |
μm |
T38253 |
1380-1381 |
. |
denotes |
. |
T38254 |
1381-1407 |
sentence |
denotes |
M, molecular size marker. |
T38255 |
1382-1383 |
NN |
denotes |
M |
T38256 |
1383-1385 |
, |
denotes |
, |
T38257 |
1385-1394 |
JJ |
denotes |
molecular |
T38258 |
1395-1399 |
NN |
denotes |
size |
T38259 |
1400-1406 |
NN |
denotes |
marker |
T38260 |
1406-1407 |
. |
denotes |
. |
R11341 |
T37915 |
T37916 |
det |
The,Isoform |
R11342 |
T37916 |
T37918 |
nsubj |
Isoform,Drives |
R11343 |
T37917 |
T37916 |
compound |
E2f3a,Isoform |
R11344 |
T37919 |
T37920 |
det |
the,Defect |
R11345 |
T37920 |
T37918 |
dobj |
Defect,Drives |
R11346 |
T37921 |
T37920 |
compound |
Differentiation,Defect |
R11347 |
T37922 |
T37918 |
prep |
in,Drives |
R11348 |
T37923 |
T37924 |
compound |
Rb,KO |
R11349 |
T37924 |
T37925 |
compound |
KO,SACs |
R11350 |
T37925 |
T37922 |
pobj |
SACs,in |
R11351 |
T37927 |
T37928 |
punct |
(,A |
R11352 |
T37928 |
T37929 |
meta |
A,diagrams |
R11353 |
T37930 |
T37928 |
punct |
),A |
R11354 |
T37931 |
T37929 |
amod |
Schematic,diagrams |
R11355 |
T37932 |
T37929 |
prep |
of,diagrams |
R11356 |
T37933 |
T37934 |
det |
the,WT |
R11357 |
T37934 |
T37932 |
pobj |
WT,of |
R11358 |
T37935 |
T37934 |
compound |
mouse,WT |
R11359 |
T37936 |
T37934 |
punct |
", ",WT |
R11360 |
T37937 |
T37934 |
conj |
E2f3a,WT |
R11361 |
T37938 |
T37937 |
punct |
−,E2f3a |
R11362 |
T37939 |
T37937 |
punct |
/,E2f3a |
R11363 |
T37940 |
T37937 |
punct |
−,E2f3a |
R11364 |
T37941 |
T37937 |
punct |
", ",E2f3a |
R11365 |
T37942 |
T37937 |
cc |
and,E2f3a |
R11366 |
T37943 |
T37944 |
det |
the,loci |
R11367 |
T37944 |
T37937 |
conj |
loci,E2f3a |
R11368 |
T37945 |
T37944 |
nmod |
Cre,loci |
R11369 |
T37946 |
T37945 |
punct |
-,Cre |
R11370 |
T37947 |
T37945 |
amod |
recombined,Cre |
R11371 |
T37948 |
T37944 |
amod |
floxed,loci |
R11372 |
T37949 |
T37944 |
compound |
E2f3,loci |
R11373 |
T37950 |
T37944 |
punct |
(,loci |
R11374 |
T37951 |
T37944 |
acl |
indicated,loci |
R11375 |
T37952 |
T37951 |
advmod |
here,indicated |
R11376 |
T37953 |
T37951 |
prep |
as,indicated |
R11377 |
T37954 |
T37953 |
pobj |
E2f3,as |
R11378 |
T37955 |
T37954 |
punct |
−,E2f3 |
R11379 |
T37956 |
T37954 |
punct |
/,E2f3 |
R11380 |
T37957 |
T37954 |
punct |
−,E2f3 |
R11381 |
T37958 |
T37951 |
prep |
for,indicated |
R11382 |
T37959 |
T37958 |
pobj |
simplicity,for |
R11383 |
T37960 |
T37929 |
punct |
),diagrams |
R11384 |
T37961 |
T37929 |
punct |
.,diagrams |
R11385 |
T37963 |
T37964 |
nmod |
E2f3a,mice |
R11386 |
T37964 |
T37968 |
nsubj |
mice,lack |
R11387 |
T37965 |
T37963 |
punct |
−,E2f3a |
R11388 |
T37966 |
T37963 |
punct |
/,E2f3a |
R11389 |
T37967 |
T37963 |
punct |
−,E2f3a |
R11390 |
T37969 |
T37968 |
dobj |
most,lack |
R11391 |
T37970 |
T37969 |
prep |
of,most |
R11392 |
T37971 |
T37972 |
compound |
E2f3,1a |
R11393 |
T37972 |
T37970 |
pobj |
1a,of |
R11394 |
T37973 |
T37972 |
compound |
exon,1a |
R11395 |
T37974 |
T37969 |
cc |
and,most |
R11396 |
T37975 |
T37969 |
conj |
part,most |
R11397 |
T37976 |
T37975 |
prep |
of,part |
R11398 |
T37977 |
T37978 |
compound |
intron,1a |
R11399 |
T37978 |
T37976 |
pobj |
1a,of |
R11400 |
T37979 |
T37980 |
punct |
(,box |
R11401 |
T37980 |
T37968 |
parataxis |
box,lack |
R11402 |
T37981 |
T37980 |
amod |
red,box |
R11403 |
T37982 |
T37980 |
amod |
dotted,box |
R11404 |
T37983 |
T37980 |
punct |
),box |
R11405 |
T37984 |
T37968 |
punct |
.,lack |
R11406 |
T37986 |
T37987 |
nsubj |
Arrows,indicate |
R11407 |
T37988 |
T37989 |
compound |
PCR,primers |
R11408 |
T37989 |
T37987 |
dobj |
primers,indicate |
R11409 |
T37990 |
T37987 |
punct |
.,indicate |
R11410 |
T37992 |
T37993 |
nsubjpass |
Genotyping,shown |
R11411 |
T37994 |
T37992 |
prep |
of,Genotyping |
R11412 |
T37995 |
T37996 |
det |
an,mouse |
R11413 |
T37996 |
T37994 |
pobj |
mouse,of |
R11414 |
T37997 |
T37996 |
nmod |
E2f3a,mouse |
R11415 |
T37998 |
T37997 |
punct |
+,E2f3a |
R11416 |
T37999 |
T37997 |
punct |
/,E2f3a |
R11417 |
T38000 |
T37997 |
punct |
−,E2f3a |
R11418 |
T38001 |
T37993 |
auxpass |
is,shown |
R11419 |
T38002 |
T37993 |
prep |
on,shown |
R11420 |
T38003 |
T38004 |
det |
the,right |
R11421 |
T38004 |
T38002 |
pobj |
right,on |
R11422 |
T38005 |
T37993 |
punct |
.,shown |
R11423 |
T38007 |
T38008 |
punct |
(,B |
R11424 |
T38008 |
T38009 |
meta |
B,detection |
R11425 |
T38010 |
T38008 |
punct |
),B |
R11426 |
T38011 |
T38012 |
compound |
RT,PCR |
R11427 |
T38012 |
T38009 |
compound |
PCR,detection |
R11428 |
T38013 |
T38012 |
punct |
-,PCR |
R11429 |
T38014 |
T38009 |
prep |
of,detection |
R11430 |
T38015 |
T38016 |
nmod |
E2f3a,mRNA |
R11431 |
T38016 |
T38014 |
pobj |
mRNA,of |
R11432 |
T38017 |
T38015 |
cc |
and,E2f3a |
R11433 |
T38018 |
T38015 |
conj |
E2f3b,E2f3a |
R11434 |
T38019 |
T38009 |
prep |
in,detection |
R11435 |
T38020 |
T38021 |
det |
the,retina |
R11436 |
T38021 |
T38019 |
pobj |
retina,in |
R11437 |
T38022 |
T38009 |
punct |
.,detection |
R11438 |
T38024 |
T38025 |
det |
The,sequences |
R11439 |
T38025 |
T38026 |
nsubj |
sequences,are |
R11440 |
T38027 |
T38025 |
prep |
of,sequences |
R11441 |
T38028 |
T38027 |
pobj |
primers,of |
R11442 |
T38029 |
T38026 |
attr |
1aF,are |
R11443 |
T38030 |
T38029 |
punct |
(,1aF |
R11444 |
T38031 |
T38032 |
nummod |
5,GCCTCTACACCACGCCACAAG |
R11445 |
T38032 |
T38029 |
appos |
GCCTCTACACCACGCCACAAG,1aF |
R11446 |
T38033 |
T38031 |
punct |
′,5 |
R11447 |
T38034 |
T38032 |
punct |
-,GCCTCTACACCACGCCACAAG |
R11448 |
T38035 |
T38032 |
punct |
-,GCCTCTACACCACGCCACAAG |
R11449 |
T38036 |
T38032 |
nummod |
3,GCCTCTACACCACGCCACAAG |
R11450 |
T38037 |
T38032 |
punct |
′,GCCTCTACACCACGCCACAAG |
R11451 |
T38038 |
T38029 |
punct |
),1aF |
R11452 |
T38039 |
T38029 |
punct |
", ",1aF |
R11453 |
T38040 |
T38029 |
conj |
1bF,1aF |
R11454 |
T38041 |
T38040 |
punct |
(,1bF |
R11455 |
T38042 |
T38043 |
nummod |
5,CGGAAATGCCCTTACAGC |
R11456 |
T38043 |
T38040 |
appos |
CGGAAATGCCCTTACAGC,1bF |
R11457 |
T38044 |
T38042 |
punct |
′,5 |
R11458 |
T38045 |
T38043 |
punct |
-,CGGAAATGCCCTTACAGC |
R11459 |
T38046 |
T38043 |
punct |
-,CGGAAATGCCCTTACAGC |
R11460 |
T38047 |
T38043 |
nummod |
3,CGGAAATGCCCTTACAGC |
R11461 |
T38048 |
T38043 |
punct |
′,CGGAAATGCCCTTACAGC |
R11462 |
T38049 |
T38040 |
punct |
),1bF |
R11463 |
T38050 |
T38040 |
punct |
", ",1bF |
R11464 |
T38051 |
T38040 |
cc |
and,1bF |
R11465 |
T38052 |
T38040 |
conj |
4R,1bF |
R11466 |
T38053 |
T38052 |
punct |
(,4R |
R11467 |
T38054 |
T38055 |
nummod |
5,CTCAGTCACTTCTTTGGACAG |
R11468 |
T38055 |
T38052 |
appos |
CTCAGTCACTTCTTTGGACAG,4R |
R11469 |
T38056 |
T38054 |
punct |
′,5 |
R11470 |
T38057 |
T38055 |
punct |
-,CTCAGTCACTTCTTTGGACAG |
R11471 |
T38058 |
T38055 |
punct |
-,CTCAGTCACTTCTTTGGACAG |
R11472 |
T38059 |
T38055 |
nummod |
3,CTCAGTCACTTCTTTGGACAG |
R11473 |
T38060 |
T38055 |
punct |
′,CTCAGTCACTTCTTTGGACAG |
R11474 |
T38061 |
T38026 |
punct |
),are |
R11475 |
T38062 |
T38026 |
punct |
.,are |
R11476 |
T38064 |
T38065 |
compound |
WT,retina |
R11477 |
T38065 |
T38066 |
nsubj |
retina,expresses |
R11478 |
T38067 |
T38068 |
preconj |
both,E2f3a |
R11479 |
T38068 |
T38069 |
nmod |
E2f3a,mRNA |
R11480 |
T38069 |
T38066 |
dobj |
mRNA,expresses |
R11481 |
T38070 |
T38068 |
cc |
and,E2f3a |
R11482 |
T38071 |
T38068 |
conj |
E2f3b,E2f3a |
R11483 |
T38072 |
T38066 |
punct |
.,expresses |
R11484 |
T38074 |
T38075 |
mark |
As,expected |
R11485 |
T38075 |
T38076 |
advcl |
expected,lacks |
R11486 |
T38077 |
T38076 |
punct |
", ",lacks |
R11487 |
T38078 |
T38079 |
nmod |
E2f3a,retina |
R11488 |
T38079 |
T38076 |
nsubj |
retina,lacks |
R11489 |
T38080 |
T38078 |
punct |
−,E2f3a |
R11490 |
T38081 |
T38078 |
punct |
/,E2f3a |
R11491 |
T38082 |
T38078 |
punct |
−,E2f3a |
R11492 |
T38083 |
T38084 |
compound |
E2f3a,mRNA |
R11493 |
T38084 |
T38076 |
dobj |
mRNA,lacks |
R11494 |
T38085 |
T38076 |
cc |
and,lacks |
R11495 |
T38086 |
T38087 |
advmod |
still,expresses |
R11496 |
T38087 |
T38076 |
conj |
expresses,lacks |
R11497 |
T38088 |
T38089 |
compound |
E2f3b,mRNA |
R11498 |
T38089 |
T38087 |
dobj |
mRNA,expresses |
R11499 |
T38090 |
T38076 |
punct |
.,lacks |
R11500 |
T38092 |
T38093 |
nmod |
E2f3,retina |
R11501 |
T38093 |
T38097 |
nsubj |
retina,lacks |
R11502 |
T38094 |
T38092 |
punct |
−,E2f3 |
R11503 |
T38095 |
T38092 |
punct |
/,E2f3 |
R11504 |
T38096 |
T38092 |
punct |
−,E2f3 |
R11505 |
T38098 |
T38099 |
amod |
full,length |
R11506 |
T38099 |
T38101 |
nmod |
length,mRNAs |
R11507 |
T38100 |
T38099 |
punct |
-,length |
R11508 |
T38101 |
T38097 |
dobj |
mRNAs,lacks |
R11509 |
T38102 |
T38101 |
nmod |
E2f3a,mRNAs |
R11510 |
T38103 |
T38102 |
cc |
and,E2f3a |
R11511 |
T38104 |
T38102 |
conj |
E2f3b,E2f3a |
R11512 |
T38105 |
T38097 |
punct |
", ",lacks |
R11513 |
T38106 |
T38097 |
cc |
and,lacks |
R11514 |
T38107 |
T38108 |
advmod |
instead,expresses |
R11515 |
T38108 |
T38097 |
conj |
expresses,lacks |
R11516 |
T38109 |
T38110 |
det |
a,mRNA |
R11517 |
T38110 |
T38108 |
dobj |
mRNA,expresses |
R11518 |
T38111 |
T38110 |
amod |
truncated,mRNA |
R11519 |
T38112 |
T38110 |
acl |
lacking,mRNA |
R11520 |
T38113 |
T38112 |
dobj |
exon,lacking |
R11521 |
T38114 |
T38113 |
nummod |
3,exon |
R11522 |
T38115 |
T38097 |
punct |
.,lacks |
R11523 |
T38117 |
T38118 |
punct |
(,C |
R11524 |
T38118 |
T38119 |
meta |
C,analysis |
R11525 |
T38120 |
T38118 |
punct |
),C |
R11526 |
T38121 |
T38122 |
amod |
Real,time |
R11527 |
T38122 |
T38119 |
compound |
time,analysis |
R11528 |
T38123 |
T38122 |
punct |
-,time |
R11529 |
T38124 |
T38125 |
compound |
RT,PCR |
R11530 |
T38125 |
T38119 |
compound |
PCR,analysis |
R11531 |
T38126 |
T38125 |
punct |
-,PCR |
R11532 |
T38127 |
T38119 |
prep |
of,analysis |
R11533 |
T38128 |
T38129 |
compound |
E2f,genes |
R11534 |
T38129 |
T38127 |
pobj |
genes,of |
R11535 |
T38130 |
T38119 |
prep |
in,analysis |
R11536 |
T38131 |
T38132 |
compound |
P8,retinas |
R11537 |
T38132 |
T38130 |
pobj |
retinas,in |
R11538 |
T38133 |
T38132 |
prep |
of,retinas |
R11539 |
T38134 |
T38135 |
det |
the,genotypes |
R11540 |
T38135 |
T38133 |
pobj |
genotypes,of |
R11541 |
T38136 |
T38135 |
amod |
indicated,genotypes |
R11542 |
T38137 |
T38119 |
punct |
.,analysis |
R11543 |
T38139 |
T38140 |
compound |
Error,bars |
R11544 |
T38140 |
T38141 |
nsubj |
bars,represent |
R11545 |
T38142 |
T38141 |
dobj |
SD,represent |
R11546 |
T38143 |
T38142 |
prep |
of,SD |
R11547 |
T38144 |
T38143 |
pobj |
measurements,of |
R11548 |
T38145 |
T38144 |
prep |
from,measurements |
R11549 |
T38146 |
T38147 |
nummod |
three,animals |
R11550 |
T38147 |
T38145 |
pobj |
animals,from |
R11551 |
T38148 |
T38141 |
punct |
", ",represent |
R11552 |
T38149 |
T38141 |
cc |
and,represent |
R11553 |
T38150 |
T38151 |
nsubj |
asterisks,indicate |
R11554 |
T38151 |
T38141 |
conj |
indicate,represent |
R11555 |
T38152 |
T38153 |
det |
a,difference |
R11556 |
T38153 |
T38151 |
dobj |
difference,indicate |
R11557 |
T38154 |
T38153 |
amod |
significant,difference |
R11558 |
T38155 |
T38153 |
prep |
between,difference |
R11559 |
T38156 |
T38155 |
pobj |
WT,between |
R11560 |
T38157 |
T38156 |
cc |
and,WT |
R11561 |
T38158 |
T38159 |
det |
the,indicated |
R11562 |
T38159 |
T38160 |
nmod |
indicated,genotypes |
R11563 |
T38160 |
T38156 |
conj |
genotypes,WT |
R11564 |
T38161 |
T38162 |
punct |
(,test |
R11565 |
T38162 |
T38153 |
parataxis |
test,difference |
R11566 |
T38163 |
T38164 |
punct |
*,0.05 |
R11567 |
T38164 |
T38162 |
ccomp |
0.05,test |
R11568 |
T38165 |
T38164 |
punct |
", ",0.05 |
R11569 |
T38166 |
T38164 |
nsubj |
p,0.05 |
R11570 |
T38167 |
T38164 |
punct |
<,0.05 |
R11571 |
T38168 |
T38162 |
punct |
;,test |
R11572 |
T38169 |
T38170 |
punct |
**,0.01 |
R11573 |
T38170 |
T38162 |
ccomp |
0.01,test |
R11574 |
T38171 |
T38170 |
punct |
;,0.01 |
R11575 |
T38172 |
T38170 |
nsubj |
p,0.01 |
R11576 |
T38173 |
T38170 |
punct |
<,0.01 |
R11577 |
T38174 |
T38162 |
punct |
;,test |
R11578 |
T38175 |
T38162 |
nmod |
ANOVA,test |
R11579 |
T38176 |
T38175 |
cc |
and,ANOVA |
R11580 |
T38177 |
T38178 |
compound |
Tukey,HSD |
R11581 |
T38178 |
T38175 |
conj |
HSD,ANOVA |
R11582 |
T38179 |
T38162 |
punct |
),test |
R11583 |
T38180 |
T38151 |
punct |
.,indicate |
R11584 |
T38182 |
T38183 |
punct |
(,D |
R11585 |
T38183 |
T38184 |
meta |
D,Rescue |
R11586 |
T38185 |
T38183 |
punct |
),D |
R11587 |
T38186 |
T38184 |
prep |
of,Rescue |
R11588 |
T38187 |
T38188 |
compound |
Rb,KO |
R11589 |
T38188 |
T38189 |
compound |
KO,SACs |
R11590 |
T38189 |
T38186 |
pobj |
SACs,of |
R11591 |
T38190 |
T38184 |
prep |
by,Rescue |
R11592 |
T38191 |
T38192 |
compound |
E2f3a,deletion |
R11593 |
T38192 |
T38190 |
pobj |
deletion,by |
R11594 |
T38193 |
T38184 |
punct |
.,Rescue |
R11595 |
T38195 |
T38196 |
amod |
Horizontal,sections |
R11596 |
T38196 |
T38198 |
nsubjpass |
sections,stained |
R11597 |
T38197 |
T38196 |
amod |
retinal,sections |
R11598 |
T38199 |
T38196 |
prep |
of,sections |
R11599 |
T38200 |
T38201 |
det |
the,genotypes |
R11600 |
T38201 |
T38199 |
pobj |
genotypes,of |
R11601 |
T38202 |
T38201 |
amod |
indicated,genotypes |
R11602 |
T38203 |
T38201 |
cc |
and,genotypes |
R11603 |
T38204 |
T38201 |
conj |
ages,genotypes |
R11604 |
T38205 |
T38198 |
auxpass |
were,stained |
R11605 |
T38206 |
T38198 |
prep |
for,stained |
R11606 |
T38207 |
T38206 |
pobj |
nuclei,for |
R11607 |
T38208 |
T38209 |
punct |
(,blue |
R11608 |
T38209 |
T38207 |
parataxis |
blue,nuclei |
R11609 |
T38210 |
T38209 |
dep |
DAPI,blue |
R11610 |
T38211 |
T38209 |
punct |
", ",blue |
R11611 |
T38212 |
T38209 |
punct |
),blue |
R11612 |
T38213 |
T38207 |
punct |
", ",nuclei |
R11613 |
T38214 |
T38215 |
compound |
M,phase |
R11614 |
T38215 |
T38207 |
conj |
phase,nuclei |
R11615 |
T38216 |
T38215 |
punct |
-,phase |
R11616 |
T38217 |
T38218 |
punct |
(,green |
R11617 |
T38218 |
T38215 |
parataxis |
green,phase |
R11618 |
T38219 |
T38218 |
dep |
PH3,green |
R11619 |
T38220 |
T38218 |
punct |
", ",green |
R11620 |
T38221 |
T38218 |
punct |
),green |
R11621 |
T38222 |
T38215 |
punct |
", ",phase |
R11622 |
T38223 |
T38215 |
cc |
and,phase |
R11623 |
T38224 |
T38225 |
det |
the,marker |
R11624 |
T38225 |
T38215 |
conj |
marker,phase |
R11625 |
T38226 |
T38225 |
compound |
SAC,marker |
R11626 |
T38227 |
T38225 |
appos |
Slc18a3,marker |
R11627 |
T38228 |
T38229 |
punct |
(,red |
R11628 |
T38229 |
T38225 |
parataxis |
red,marker |
R11629 |
T38230 |
T38229 |
punct |
),red |
R11630 |
T38231 |
T38198 |
punct |
.,stained |
R11631 |
T38233 |
T38234 |
compound |
E2f3a,deletion |
R11632 |
T38234 |
T38235 |
nsubj |
deletion,suppress |
R11633 |
T38236 |
T38235 |
aux |
does,suppress |
R11634 |
T38237 |
T38235 |
neg |
not,suppress |
R11635 |
T38238 |
T38239 |
amod |
ectopic,division |
R11636 |
T38239 |
T38235 |
dobj |
division,suppress |
R11637 |
T38240 |
T38235 |
punct |
", ",suppress |
R11638 |
T38241 |
T38235 |
cc |
but,suppress |
R11639 |
T38242 |
T38235 |
conj |
rescues,suppress |
R11640 |
T38243 |
T38244 |
det |
the,defect |
R11641 |
T38244 |
T38242 |
dobj |
defect,rescues |
R11642 |
T38245 |
T38244 |
compound |
SAC,defect |
R11643 |
T38246 |
T38235 |
punct |
.,suppress |
R11644 |
T38248 |
T38249 |
compound |
Scale,bars |
R11645 |
T38249 |
T38250 |
nsubj |
bars,are |
R11646 |
T38251 |
T38252 |
nummod |
50,μm |
R11647 |
T38252 |
T38250 |
attr |
μm,are |
R11648 |
T38253 |
T38250 |
punct |
.,are |
R11649 |
T38256 |
T38255 |
punct |
", ",M |
R11650 |
T38257 |
T38258 |
amod |
molecular,size |
R11651 |
T38258 |
T38259 |
compound |
size,marker |
R11652 |
T38259 |
T38255 |
appos |
marker,M |
R11653 |
T38260 |
T38255 |
punct |
.,M |