Id |
Subject |
Object |
Predicate |
Lexical cue |
T11352 |
0-5 |
NN |
denotes |
Light |
T11354 |
5-6 |
HYPH |
denotes |
- |
T11353 |
6-13 |
VBN |
denotes |
adapted |
T11356 |
14-15 |
-LRB- |
denotes |
( |
T11357 |
15-23 |
JJ |
denotes |
photopic |
T11358 |
23-24 |
-RRB- |
denotes |
) |
T11355 |
25-35 |
NNS |
denotes |
recordings |
T11360 |
36-38 |
TO |
denotes |
to |
T11362 |
39-51 |
RB |
denotes |
specifically |
T11361 |
52-58 |
VB |
denotes |
assess |
T11363 |
59-62 |
DT |
denotes |
the |
T11365 |
63-67 |
NN |
denotes |
cone |
T11364 |
68-74 |
NN |
denotes |
system |
T11359 |
75-82 |
VBD |
denotes |
yielded |
T11366 |
83-93 |
JJ |
denotes |
comparable |
T11367 |
94-101 |
NNS |
denotes |
results |
T11368 |
101-102 |
. |
denotes |
. |
T11369 |
102-339 |
sentence |
denotes |
Cones represent only 3% of photoreceptors and, unlike rods, develop without Rb, but they require rods for survival, and in the Rb KO retina, they have abnormal morphology and their synaptic targets, bipolar cells, are much depleted [2]. |
T11370 |
103-108 |
NNS |
denotes |
Cones |
T11371 |
109-118 |
VBP |
denotes |
represent |
T11372 |
119-123 |
RB |
denotes |
only |
T11373 |
124-125 |
CD |
denotes |
3 |
T11374 |
125-126 |
NN |
denotes |
% |
T11375 |
127-129 |
IN |
denotes |
of |
T11376 |
130-144 |
NNS |
denotes |
photoreceptors |
T11377 |
145-148 |
CC |
denotes |
and |
T11378 |
148-150 |
, |
denotes |
, |
T11379 |
150-156 |
JJ |
denotes |
unlike |
T11381 |
157-161 |
NNS |
denotes |
rods |
T11382 |
161-163 |
, |
denotes |
, |
T11380 |
163-170 |
VBP |
denotes |
develop |
T11383 |
171-178 |
IN |
denotes |
without |
T11384 |
179-181 |
NN |
denotes |
Rb |
T11385 |
181-183 |
, |
denotes |
, |
T11386 |
183-186 |
CC |
denotes |
but |
T11387 |
187-191 |
PRP |
denotes |
they |
T11388 |
192-199 |
VBP |
denotes |
require |
T11389 |
200-204 |
NNS |
denotes |
rods |
T11390 |
205-208 |
IN |
denotes |
for |
T11391 |
209-217 |
NN |
denotes |
survival |
T11392 |
217-219 |
, |
denotes |
, |
T11393 |
219-222 |
CC |
denotes |
and |
T11394 |
223-225 |
IN |
denotes |
in |
T11396 |
226-229 |
DT |
denotes |
the |
T11398 |
230-232 |
NN |
denotes |
Rb |
T11399 |
233-235 |
NN |
denotes |
KO |
T11397 |
236-242 |
NN |
denotes |
retina |
T11400 |
242-244 |
, |
denotes |
, |
T11401 |
244-248 |
PRP |
denotes |
they |
T11395 |
249-253 |
VBP |
denotes |
have |
T11402 |
254-262 |
JJ |
denotes |
abnormal |
T11403 |
263-273 |
NN |
denotes |
morphology |
T11404 |
274-277 |
CC |
denotes |
and |
T11405 |
278-283 |
PRP$ |
denotes |
their |
T11407 |
284-292 |
JJ |
denotes |
synaptic |
T11406 |
293-300 |
NNS |
denotes |
targets |
T11409 |
300-302 |
, |
denotes |
, |
T11410 |
302-309 |
JJ |
denotes |
bipolar |
T11411 |
310-315 |
NNS |
denotes |
cells |
T11412 |
315-317 |
, |
denotes |
, |
T11408 |
317-320 |
VBP |
denotes |
are |
T11413 |
321-325 |
RB |
denotes |
much |
T11414 |
326-334 |
JJ |
denotes |
depleted |
T11415 |
335-336 |
-LRB- |
denotes |
[ |
T11416 |
336-337 |
CD |
denotes |
2 |
T11417 |
337-338 |
-RRB- |
denotes |
] |
T11418 |
338-339 |
. |
denotes |
. |
T11419 |
339-506 |
sentence |
denotes |
The photopic response, a product of cone and mainly bipolar activity, was much reduced by Rb loss, but was rescued considerably in the Rb/E2f1 DKO retina (Figure S5). |
T11420 |
340-343 |
DT |
denotes |
The |
T11422 |
344-352 |
JJ |
denotes |
photopic |
T11421 |
353-361 |
NN |
denotes |
response |
T11424 |
361-363 |
, |
denotes |
, |
T11425 |
363-364 |
DT |
denotes |
a |
T11426 |
365-372 |
NN |
denotes |
product |
T11427 |
373-375 |
IN |
denotes |
of |
T11428 |
376-380 |
NN |
denotes |
cone |
T11430 |
381-384 |
CC |
denotes |
and |
T11431 |
385-391 |
RB |
denotes |
mainly |
T11432 |
392-399 |
JJ |
denotes |
bipolar |
T11429 |
400-408 |
NN |
denotes |
activity |
T11433 |
408-410 |
, |
denotes |
, |
T11434 |
410-413 |
VBD |
denotes |
was |
T11435 |
414-418 |
RB |
denotes |
much |
T11423 |
419-426 |
VBN |
denotes |
reduced |
T11436 |
427-429 |
IN |
denotes |
by |
T11437 |
430-432 |
NN |
denotes |
Rb |
T11438 |
433-437 |
NN |
denotes |
loss |
T11439 |
437-439 |
, |
denotes |
, |
T11440 |
439-442 |
CC |
denotes |
but |
T11441 |
443-446 |
VBD |
denotes |
was |
T11442 |
447-454 |
VBN |
denotes |
rescued |
T11443 |
455-467 |
RB |
denotes |
considerably |
T11444 |
468-470 |
IN |
denotes |
in |
T11445 |
471-474 |
DT |
denotes |
the |
T11447 |
475-477 |
NN |
denotes |
Rb |
T11449 |
477-478 |
HYPH |
denotes |
/ |
T11448 |
478-482 |
NN |
denotes |
E2f1 |
T11450 |
483-486 |
NN |
denotes |
DKO |
T11446 |
487-493 |
NN |
denotes |
retina |
T11451 |
494-495 |
-LRB- |
denotes |
( |
T11453 |
495-501 |
NN |
denotes |
Figure |
T11452 |
502-504 |
NN |
denotes |
S5 |
T11454 |
504-505 |
-RRB- |
denotes |
) |
T11455 |
505-506 |
. |
denotes |
. |
T11456 |
506-577 |
sentence |
denotes |
Again, the median amplitude lay at the lower end of the E2f1 KO range. |
T11457 |
507-512 |
RB |
denotes |
Again |
T11459 |
512-514 |
, |
denotes |
, |
T11460 |
514-517 |
DT |
denotes |
the |
T11462 |
518-524 |
JJ |
denotes |
median |
T11461 |
525-534 |
NN |
denotes |
amplitude |
T11458 |
535-538 |
VBD |
denotes |
lay |
T11463 |
539-541 |
IN |
denotes |
at |
T11464 |
542-545 |
DT |
denotes |
the |
T11466 |
546-551 |
JJ |
denotes |
lower |
T11465 |
552-555 |
NN |
denotes |
end |
T11467 |
556-558 |
IN |
denotes |
of |
T11468 |
559-562 |
DT |
denotes |
the |
T11470 |
563-567 |
NN |
denotes |
E2f1 |
T11471 |
568-570 |
NN |
denotes |
KO |
T11469 |
571-576 |
NN |
denotes |
range |
T11472 |
576-577 |
. |
denotes |
. |
T11473 |
577-910 |
sentence |
denotes |
The photopic response in E2f1 KO mice was slightly reduced relative to WT (Figure S5B), possibly because E2f1 is required for maximal expansion of embryonic RPCs, and the E2f1 KO retina has, as noted earlier, slightly fewer cells than the WT retina, although cell type proportions are unaffected (D. C. and R. B., unpublished data). |
T11474 |
578-581 |
DT |
denotes |
The |
T11476 |
582-590 |
JJ |
denotes |
photopic |
T11475 |
591-599 |
NN |
denotes |
response |
T11478 |
600-602 |
IN |
denotes |
in |
T11479 |
603-607 |
NN |
denotes |
E2f1 |
T11480 |
608-610 |
NN |
denotes |
KO |
T11481 |
611-615 |
NNS |
denotes |
mice |
T11482 |
616-619 |
VBD |
denotes |
was |
T11483 |
620-628 |
RB |
denotes |
slightly |
T11477 |
629-636 |
VBN |
denotes |
reduced |
T11484 |
637-645 |
JJ |
denotes |
relative |
T11485 |
646-648 |
IN |
denotes |
to |
T11486 |
649-651 |
NN |
denotes |
WT |
T11487 |
652-653 |
-LRB- |
denotes |
( |
T11489 |
653-659 |
NN |
denotes |
Figure |
T11488 |
660-663 |
NN |
denotes |
S5B |
T11490 |
663-664 |
-RRB- |
denotes |
) |
T11491 |
664-666 |
, |
denotes |
, |
T11492 |
666-674 |
RB |
denotes |
possibly |
T11494 |
675-682 |
IN |
denotes |
because |
T11495 |
683-687 |
NN |
denotes |
E2f1 |
T11496 |
688-690 |
VBZ |
denotes |
is |
T11493 |
691-699 |
VBN |
denotes |
required |
T11497 |
700-703 |
IN |
denotes |
for |
T11498 |
704-711 |
JJ |
denotes |
maximal |
T11499 |
712-721 |
NN |
denotes |
expansion |
T11500 |
722-724 |
IN |
denotes |
of |
T11501 |
725-734 |
JJ |
denotes |
embryonic |
T11502 |
735-739 |
NNS |
denotes |
RPCs |
T11503 |
739-741 |
, |
denotes |
, |
T11504 |
741-744 |
CC |
denotes |
and |
T11505 |
745-748 |
DT |
denotes |
the |
T11507 |
749-753 |
NN |
denotes |
E2f1 |
T11508 |
754-756 |
NN |
denotes |
KO |
T11506 |
757-763 |
NN |
denotes |
retina |
T11509 |
764-767 |
VBZ |
denotes |
has |
T11510 |
767-769 |
, |
denotes |
, |
T11511 |
769-771 |
IN |
denotes |
as |
T11512 |
772-777 |
VBN |
denotes |
noted |
T11513 |
778-785 |
RBR |
denotes |
earlier |
T11514 |
785-787 |
, |
denotes |
, |
T11515 |
787-795 |
RB |
denotes |
slightly |
T11516 |
796-801 |
JJR |
denotes |
fewer |
T11517 |
802-807 |
NNS |
denotes |
cells |
T11518 |
808-812 |
IN |
denotes |
than |
T11519 |
813-816 |
DT |
denotes |
the |
T11521 |
817-819 |
NN |
denotes |
WT |
T11520 |
820-826 |
NN |
denotes |
retina |
T11522 |
826-828 |
, |
denotes |
, |
T11523 |
828-836 |
IN |
denotes |
although |
T11525 |
837-841 |
NN |
denotes |
cell |
T11526 |
842-846 |
NN |
denotes |
type |
T11527 |
847-858 |
NNS |
denotes |
proportions |
T11524 |
859-862 |
VBP |
denotes |
are |
T11528 |
863-873 |
JJ |
denotes |
unaffected |
T11529 |
874-875 |
-LRB- |
denotes |
( |
T11530 |
875-877 |
NNP |
denotes |
D. |
T11531 |
878-880 |
NNP |
denotes |
C. |
T11532 |
881-884 |
CC |
denotes |
and |
T11533 |
885-887 |
NNP |
denotes |
R. |
T11534 |
888-890 |
NNP |
denotes |
B. |
T11535 |
890-892 |
, |
denotes |
, |
T11536 |
892-903 |
JJ |
denotes |
unpublished |
T11537 |
904-908 |
NNS |
denotes |
data |
T11538 |
908-909 |
-RRB- |
denotes |
) |
T11539 |
909-910 |
. |
denotes |
. |
T11540 |
910-1149 |
sentence |
denotes |
Thus, marginally subnormal photopic responses in the Rb/E2f1 DKO retina can be attributed to both a reduction of cone numbers in E2f1 KO mice alone, and a “genuine” slight reduction in cone function attributable to Rb loss relative to WT. |
T11541 |
911-915 |
RB |
denotes |
Thus |
T11543 |
915-917 |
, |
denotes |
, |
T11544 |
917-927 |
RB |
denotes |
marginally |
T11545 |
928-937 |
JJ |
denotes |
subnormal |
T11547 |
938-946 |
JJ |
denotes |
photopic |
T11546 |
947-956 |
NNS |
denotes |
responses |
T11548 |
957-959 |
IN |
denotes |
in |
T11549 |
960-963 |
DT |
denotes |
the |
T11551 |
964-966 |
NN |
denotes |
Rb |
T11553 |
966-967 |
HYPH |
denotes |
/ |
T11552 |
967-971 |
NN |
denotes |
E2f1 |
T11554 |
972-975 |
NN |
denotes |
DKO |
T11550 |
976-982 |
NN |
denotes |
retina |
T11555 |
983-986 |
MD |
denotes |
can |
T11556 |
987-989 |
VB |
denotes |
be |
T11542 |
990-1000 |
VBN |
denotes |
attributed |
T11557 |
1001-1003 |
IN |
denotes |
to |
T11558 |
1004-1008 |
CC |
denotes |
both |
T11560 |
1009-1010 |
DT |
denotes |
a |
T11559 |
1011-1020 |
NN |
denotes |
reduction |
T11561 |
1021-1023 |
IN |
denotes |
of |
T11562 |
1024-1028 |
NN |
denotes |
cone |
T11563 |
1029-1036 |
NNS |
denotes |
numbers |
T11564 |
1037-1039 |
IN |
denotes |
in |
T11565 |
1040-1044 |
NN |
denotes |
E2f1 |
T11566 |
1045-1047 |
NN |
denotes |
KO |
T11567 |
1048-1052 |
NNS |
denotes |
mice |
T11568 |
1053-1058 |
RB |
denotes |
alone |
T11569 |
1058-1060 |
, |
denotes |
, |
T11570 |
1060-1063 |
CC |
denotes |
and |
T11571 |
1064-1065 |
DT |
denotes |
a |
T11573 |
1066-1067 |
`` |
denotes |
“ |
T11574 |
1067-1074 |
JJ |
denotes |
genuine |
T11575 |
1074-1075 |
'' |
denotes |
” |
T11576 |
1076-1082 |
JJ |
denotes |
slight |
T11572 |
1083-1092 |
NN |
denotes |
reduction |
T11577 |
1093-1095 |
IN |
denotes |
in |
T11578 |
1096-1100 |
NN |
denotes |
cone |
T11579 |
1101-1109 |
NN |
denotes |
function |
T11580 |
1110-1122 |
JJ |
denotes |
attributable |
T11581 |
1123-1125 |
IN |
denotes |
to |
T11582 |
1126-1128 |
NN |
denotes |
Rb |
T11583 |
1129-1133 |
NN |
denotes |
loss |
T11584 |
1134-1142 |
JJ |
denotes |
relative |
T11585 |
1143-1145 |
IN |
denotes |
to |
T11586 |
1146-1148 |
NN |
denotes |
WT |
T11587 |
1148-1149 |
. |
denotes |
. |
T11588 |
1149-1259 |
sentence |
denotes |
This slight effect may relate to a true differentiation defect in a subset of amacrine cells discussed below. |
T11589 |
1150-1154 |
DT |
denotes |
This |
T11591 |
1155-1161 |
JJ |
denotes |
slight |
T11590 |
1162-1168 |
NN |
denotes |
effect |
T11593 |
1169-1172 |
MD |
denotes |
may |
T11592 |
1173-1179 |
VB |
denotes |
relate |
T11594 |
1180-1182 |
IN |
denotes |
to |
T11595 |
1183-1184 |
DT |
denotes |
a |
T11597 |
1185-1189 |
JJ |
denotes |
true |
T11598 |
1190-1205 |
NN |
denotes |
differentiation |
T11596 |
1206-1212 |
NN |
denotes |
defect |
T11599 |
1213-1215 |
IN |
denotes |
in |
T11600 |
1216-1217 |
DT |
denotes |
a |
T11601 |
1218-1224 |
NN |
denotes |
subset |
T11602 |
1225-1227 |
IN |
denotes |
of |
T11603 |
1228-1236 |
JJ |
denotes |
amacrine |
T11604 |
1237-1242 |
NNS |
denotes |
cells |
T11605 |
1243-1252 |
VBN |
denotes |
discussed |
T11606 |
1253-1258 |
RB |
denotes |
below |
T11607 |
1258-1259 |
. |
denotes |
. |
T11608 |
1259-1366 |
sentence |
denotes |
This discussion should not obscure the major outcome that E2f1 deletion recovers most of the ERG response. |
T11609 |
1260-1264 |
DT |
denotes |
This |
T11610 |
1265-1275 |
NN |
denotes |
discussion |
T11612 |
1276-1282 |
MD |
denotes |
should |
T11613 |
1283-1286 |
RB |
denotes |
not |
T11611 |
1287-1294 |
VB |
denotes |
obscure |
T11614 |
1295-1298 |
DT |
denotes |
the |
T11616 |
1299-1304 |
JJ |
denotes |
major |
T11615 |
1305-1312 |
NN |
denotes |
outcome |
T11617 |
1313-1317 |
IN |
denotes |
that |
T11619 |
1318-1322 |
NN |
denotes |
E2f1 |
T11620 |
1323-1331 |
NN |
denotes |
deletion |
T11618 |
1332-1340 |
VBZ |
denotes |
recovers |
T11621 |
1341-1345 |
JJS |
denotes |
most |
T11622 |
1346-1348 |
IN |
denotes |
of |
T11623 |
1349-1352 |
DT |
denotes |
the |
T11625 |
1353-1356 |
NN |
denotes |
ERG |
T11624 |
1357-1365 |
NN |
denotes |
response |
T11626 |
1365-1366 |
. |
denotes |
. |
T11627 |
1366-1478 |
sentence |
denotes |
Thus, E2f1 deletion not only rescues morphology but also both rod and cone system function in the Rb KO retina. |
T11628 |
1367-1371 |
RB |
denotes |
Thus |
T11630 |
1371-1373 |
, |
denotes |
, |
T11631 |
1373-1377 |
NN |
denotes |
E2f1 |
T11629 |
1378-1386 |
NN |
denotes |
deletion |
T11632 |
1387-1390 |
RB |
denotes |
not |
T11633 |
1391-1395 |
RB |
denotes |
only |
T11634 |
1396-1403 |
VBZ |
denotes |
rescues |
T11635 |
1404-1414 |
NN |
denotes |
morphology |
T11636 |
1415-1418 |
CC |
denotes |
but |
T11637 |
1419-1423 |
RB |
denotes |
also |
T11638 |
1424-1428 |
CC |
denotes |
both |
T11639 |
1429-1432 |
NN |
denotes |
rod |
T11641 |
1433-1436 |
CC |
denotes |
and |
T11642 |
1437-1441 |
NN |
denotes |
cone |
T11643 |
1442-1448 |
NN |
denotes |
system |
T11640 |
1449-1457 |
NN |
denotes |
function |
T11644 |
1458-1460 |
IN |
denotes |
in |
T11645 |
1461-1464 |
DT |
denotes |
the |
T11647 |
1465-1467 |
NN |
denotes |
Rb |
T11648 |
1468-1470 |
NN |
denotes |
KO |
T11646 |
1471-1477 |
NN |
denotes |
retina |
T11649 |
1477-1478 |
. |
denotes |
. |
R3238 |
T11352 |
T11353 |
npadvmod |
Light,adapted |
R3239 |
T11353 |
T11355 |
amod |
adapted,recordings |
R3240 |
T11354 |
T11353 |
punct |
-,adapted |
R3241 |
T11355 |
T11359 |
nsubj |
recordings,yielded |
R3242 |
T11356 |
T11357 |
punct |
(,photopic |
R3243 |
T11357 |
T11353 |
parataxis |
photopic,adapted |
R3244 |
T11358 |
T11357 |
punct |
),photopic |
R3245 |
T11360 |
T11361 |
aux |
to,assess |
R3246 |
T11361 |
T11355 |
advcl |
assess,recordings |
R3247 |
T11362 |
T11361 |
advmod |
specifically,assess |
R3248 |
T11363 |
T11364 |
det |
the,system |
R3249 |
T11364 |
T11361 |
dobj |
system,assess |
R3250 |
T11365 |
T11364 |
compound |
cone,system |
R3251 |
T11366 |
T11367 |
amod |
comparable,results |
R3252 |
T11367 |
T11359 |
dobj |
results,yielded |
R3253 |
T11368 |
T11359 |
punct |
.,yielded |
R3254 |
T11370 |
T11371 |
nsubj |
Cones,represent |
R3255 |
T11372 |
T11373 |
advmod |
only,3 |
R3256 |
T11373 |
T11374 |
nummod |
3,% |
R3257 |
T11374 |
T11371 |
dobj |
%,represent |
R3258 |
T11375 |
T11374 |
prep |
of,% |
R3259 |
T11376 |
T11375 |
pobj |
photoreceptors,of |
R3260 |
T11377 |
T11371 |
cc |
and,represent |
R3261 |
T11378 |
T11371 |
punct |
", ",represent |
R3262 |
T11379 |
T11380 |
prep |
unlike,develop |
R3263 |
T11380 |
T11371 |
conj |
develop,represent |
R3264 |
T11381 |
T11379 |
pobj |
rods,unlike |
R3265 |
T11382 |
T11380 |
punct |
", ",develop |
R3266 |
T11383 |
T11380 |
prep |
without,develop |
R3267 |
T11384 |
T11383 |
pobj |
Rb,without |
R3268 |
T11385 |
T11371 |
punct |
", ",represent |
R3269 |
T11386 |
T11371 |
cc |
but,represent |
R3270 |
T11387 |
T11388 |
nsubj |
they,require |
R3271 |
T11388 |
T11371 |
conj |
require,represent |
R3272 |
T11389 |
T11388 |
dobj |
rods,require |
R3273 |
T11390 |
T11388 |
prep |
for,require |
R3274 |
T11391 |
T11390 |
pobj |
survival,for |
R3275 |
T11392 |
T11388 |
punct |
", ",require |
R3276 |
T11393 |
T11388 |
cc |
and,require |
R3277 |
T11394 |
T11395 |
prep |
in,have |
R3278 |
T11395 |
T11388 |
conj |
have,require |
R3279 |
T11396 |
T11397 |
det |
the,retina |
R3280 |
T11397 |
T11394 |
pobj |
retina,in |
R3281 |
T11398 |
T11399 |
compound |
Rb,KO |
R3282 |
T11399 |
T11397 |
compound |
KO,retina |
R3283 |
T11400 |
T11395 |
punct |
", ",have |
R3284 |
T11401 |
T11395 |
nsubj |
they,have |
R3285 |
T11402 |
T11403 |
amod |
abnormal,morphology |
R3286 |
T11403 |
T11395 |
dobj |
morphology,have |
R3287 |
T11404 |
T11395 |
cc |
and,have |
R3288 |
T11405 |
T11406 |
poss |
their,targets |
R3289 |
T11406 |
T11408 |
nsubj |
targets,are |
R3290 |
T11407 |
T11406 |
amod |
synaptic,targets |
R3291 |
T11408 |
T11395 |
conj |
are,have |
R3292 |
T11409 |
T11406 |
punct |
", ",targets |
R3293 |
T11410 |
T11411 |
amod |
bipolar,cells |
R3294 |
T11411 |
T11406 |
appos |
cells,targets |
R3295 |
T11412 |
T11408 |
punct |
", ",are |
R3296 |
T11413 |
T11414 |
advmod |
much,depleted |
R3297 |
T11414 |
T11408 |
acomp |
depleted,are |
R3298 |
T11415 |
T11416 |
punct |
[,2 |
R3299 |
T11416 |
T11408 |
parataxis |
2,are |
R3300 |
T11417 |
T11416 |
punct |
],2 |
R3301 |
T11418 |
T11408 |
punct |
.,are |
R3302 |
T11420 |
T11421 |
det |
The,response |
R3303 |
T11421 |
T11423 |
nsubjpass |
response,reduced |
R3304 |
T11422 |
T11421 |
amod |
photopic,response |
R3305 |
T11424 |
T11421 |
punct |
", ",response |
R3306 |
T11425 |
T11426 |
det |
a,product |
R3307 |
T11426 |
T11421 |
appos |
product,response |
R3308 |
T11427 |
T11426 |
prep |
of,product |
R3309 |
T11428 |
T11429 |
nmod |
cone,activity |
R3310 |
T11429 |
T11427 |
pobj |
activity,of |
R3311 |
T11430 |
T11428 |
cc |
and,cone |
R3312 |
T11431 |
T11432 |
advmod |
mainly,bipolar |
R3313 |
T11432 |
T11428 |
conj |
bipolar,cone |
R3314 |
T11433 |
T11423 |
punct |
", ",reduced |
R3315 |
T11434 |
T11423 |
auxpass |
was,reduced |
R3316 |
T11435 |
T11423 |
advmod |
much,reduced |
R3317 |
T11436 |
T11423 |
agent |
by,reduced |
R3318 |
T11437 |
T11438 |
compound |
Rb,loss |
R3319 |
T11438 |
T11436 |
pobj |
loss,by |
R3320 |
T11439 |
T11423 |
punct |
", ",reduced |
R3321 |
T11440 |
T11423 |
cc |
but,reduced |
R3322 |
T11441 |
T11442 |
auxpass |
was,rescued |
R3323 |
T11442 |
T11423 |
conj |
rescued,reduced |
R3324 |
T11443 |
T11442 |
advmod |
considerably,rescued |
R3325 |
T11444 |
T11442 |
prep |
in,rescued |
R3326 |
T11445 |
T11446 |
det |
the,retina |
R3327 |
T11446 |
T11444 |
pobj |
retina,in |
R3328 |
T11447 |
T11448 |
compound |
Rb,E2f1 |
R3329 |
T11448 |
T11450 |
compound |
E2f1,DKO |
R3330 |
T11449 |
T11448 |
punct |
/,E2f1 |
R3331 |
T11450 |
T11446 |
compound |
DKO,retina |
R3332 |
T11451 |
T11452 |
punct |
(,S5 |
R3333 |
T11452 |
T11442 |
parataxis |
S5,rescued |
R3334 |
T11453 |
T11452 |
compound |
Figure,S5 |
R3335 |
T11454 |
T11452 |
punct |
),S5 |
R3336 |
T11455 |
T11423 |
punct |
.,reduced |
R3337 |
T11457 |
T11458 |
advmod |
Again,lay |
R3338 |
T11459 |
T11458 |
punct |
", ",lay |
R3339 |
T11460 |
T11461 |
det |
the,amplitude |
R3340 |
T11461 |
T11458 |
nsubj |
amplitude,lay |
R3341 |
T11462 |
T11461 |
amod |
median,amplitude |
R3342 |
T11463 |
T11458 |
prep |
at,lay |
R3343 |
T11464 |
T11465 |
det |
the,end |
R3344 |
T11465 |
T11463 |
pobj |
end,at |
R3345 |
T11466 |
T11465 |
amod |
lower,end |
R3346 |
T11467 |
T11465 |
prep |
of,end |
R3347 |
T11468 |
T11469 |
det |
the,range |
R3348 |
T11469 |
T11467 |
pobj |
range,of |
R3349 |
T11470 |
T11471 |
compound |
E2f1,KO |
R3350 |
T11471 |
T11469 |
compound |
KO,range |
R3351 |
T11472 |
T11458 |
punct |
.,lay |
R3352 |
T11474 |
T11475 |
det |
The,response |
R3353 |
T11475 |
T11477 |
nsubjpass |
response,reduced |
R3354 |
T11476 |
T11475 |
amod |
photopic,response |
R3355 |
T11478 |
T11475 |
prep |
in,response |
R3356 |
T11479 |
T11480 |
compound |
E2f1,KO |
R3357 |
T11480 |
T11481 |
compound |
KO,mice |
R3358 |
T11481 |
T11478 |
pobj |
mice,in |
R3359 |
T11482 |
T11477 |
auxpass |
was,reduced |
R3360 |
T11483 |
T11477 |
advmod |
slightly,reduced |
R3361 |
T11484 |
T11477 |
advcl |
relative,reduced |
R3362 |
T11485 |
T11484 |
prep |
to,relative |
R3363 |
T11486 |
T11485 |
pobj |
WT,to |
R3364 |
T11487 |
T11488 |
punct |
(,S5B |
R3365 |
T11488 |
T11477 |
parataxis |
S5B,reduced |
R3366 |
T11489 |
T11488 |
compound |
Figure,S5B |
R3367 |
T11490 |
T11488 |
punct |
),S5B |
R3368 |
T11491 |
T11477 |
punct |
", ",reduced |
R3369 |
T11492 |
T11493 |
advmod |
possibly,required |
R3370 |
T11493 |
T11477 |
advcl |
required,reduced |
R3371 |
T11494 |
T11493 |
mark |
because,required |
R3372 |
T11495 |
T11493 |
nsubjpass |
E2f1,required |
R3373 |
T11496 |
T11493 |
auxpass |
is,required |
R3374 |
T11497 |
T11493 |
prep |
for,required |
R3375 |
T11498 |
T11499 |
amod |
maximal,expansion |
R3376 |
T11499 |
T11497 |
pobj |
expansion,for |
R3377 |
T11500 |
T11499 |
prep |
of,expansion |
R3378 |
T11501 |
T11502 |
amod |
embryonic,RPCs |
R3379 |
T11502 |
T11500 |
pobj |
RPCs,of |
R3380 |
T11503 |
T11477 |
punct |
", ",reduced |
R3381 |
T11504 |
T11477 |
cc |
and,reduced |
R3382 |
T11505 |
T11506 |
det |
the,retina |
R3383 |
T11506 |
T11509 |
nsubj |
retina,has |
R3384 |
T11507 |
T11508 |
compound |
E2f1,KO |
R3385 |
T11508 |
T11506 |
compound |
KO,retina |
R3386 |
T11509 |
T11477 |
conj |
has,reduced |
R3387 |
T11510 |
T11509 |
punct |
", ",has |
R3388 |
T11511 |
T11512 |
mark |
as,noted |
R3389 |
T11512 |
T11509 |
advcl |
noted,has |
R3390 |
T11513 |
T11512 |
advmod |
earlier,noted |
R3391 |
T11514 |
T11509 |
punct |
", ",has |
R3392 |
T11515 |
T11516 |
advmod |
slightly,fewer |
R3393 |
T11516 |
T11517 |
amod |
fewer,cells |
R3394 |
T11517 |
T11509 |
dobj |
cells,has |
R3395 |
T11518 |
T11517 |
prep |
than,cells |
R3396 |
T11519 |
T11520 |
det |
the,retina |
R3397 |
T11520 |
T11518 |
pobj |
retina,than |
R3398 |
T11521 |
T11520 |
compound |
WT,retina |
R3399 |
T11522 |
T11509 |
punct |
", ",has |
R3400 |
T11523 |
T11524 |
mark |
although,are |
R3401 |
T11524 |
T11509 |
advcl |
are,has |
R3402 |
T11525 |
T11526 |
compound |
cell,type |
R3403 |
T11526 |
T11527 |
compound |
type,proportions |
R3404 |
T11527 |
T11524 |
nsubj |
proportions,are |
R3405 |
T11528 |
T11524 |
acomp |
unaffected,are |
R3406 |
T11529 |
T11530 |
punct |
(,D. |
R3407 |
T11530 |
T11509 |
meta |
D.,has |
R3408 |
T11531 |
T11530 |
nmod |
C.,D. |
R3409 |
T11532 |
T11530 |
cc |
and,D. |
R3410 |
T11533 |
T11530 |
conj |
R.,D. |
R3411 |
T11534 |
T11533 |
nmod |
B.,R. |
R3412 |
T11535 |
T11533 |
punct |
", ",R. |
R3413 |
T11536 |
T11537 |
amod |
unpublished,data |
R3414 |
T11537 |
T11533 |
conj |
data,R. |
R3415 |
T11538 |
T11537 |
punct |
),data |
R3416 |
T11539 |
T11509 |
punct |
.,has |
R3417 |
T11541 |
T11542 |
advmod |
Thus,attributed |
R3418 |
T11543 |
T11542 |
punct |
", ",attributed |
R3419 |
T11544 |
T11545 |
advmod |
marginally,subnormal |
R3420 |
T11545 |
T11546 |
amod |
subnormal,responses |
R3421 |
T11546 |
T11542 |
nsubjpass |
responses,attributed |
R3422 |
T11547 |
T11546 |
amod |
photopic,responses |
R3423 |
T11548 |
T11546 |
prep |
in,responses |
R3424 |
T11549 |
T11550 |
det |
the,retina |
R3425 |
T11550 |
T11548 |
pobj |
retina,in |
R3426 |
T11551 |
T11552 |
compound |
Rb,E2f1 |
R3427 |
T11552 |
T11554 |
compound |
E2f1,DKO |
R3428 |
T11553 |
T11552 |
punct |
/,E2f1 |
R3429 |
T11554 |
T11550 |
compound |
DKO,retina |
R3430 |
T11555 |
T11542 |
aux |
can,attributed |
R3431 |
T11556 |
T11542 |
auxpass |
be,attributed |
R3432 |
T11557 |
T11542 |
prep |
to,attributed |
R3433 |
T11558 |
T11559 |
preconj |
both,reduction |
R3434 |
T11559 |
T11557 |
pobj |
reduction,to |
R3435 |
T11560 |
T11559 |
det |
a,reduction |
R3436 |
T11561 |
T11559 |
prep |
of,reduction |
R3437 |
T11562 |
T11563 |
compound |
cone,numbers |
R3438 |
T11563 |
T11561 |
pobj |
numbers,of |
R3439 |
T11564 |
T11559 |
prep |
in,reduction |
R3440 |
T11565 |
T11566 |
compound |
E2f1,KO |
R3441 |
T11566 |
T11567 |
compound |
KO,mice |
R3442 |
T11567 |
T11564 |
pobj |
mice,in |
R3443 |
T11568 |
T11567 |
advmod |
alone,mice |
R3444 |
T11569 |
T11559 |
punct |
", ",reduction |
R3445 |
T11570 |
T11559 |
cc |
and,reduction |
R3446 |
T11571 |
T11572 |
det |
a,reduction |
R3447 |
T11572 |
T11559 |
conj |
reduction,reduction |
R3448 |
T11573 |
T11572 |
punct |
“,reduction |
R3449 |
T11574 |
T11572 |
amod |
genuine,reduction |
R3450 |
T11575 |
T11572 |
punct |
”,reduction |
R3451 |
T11576 |
T11572 |
amod |
slight,reduction |
R3452 |
T11577 |
T11572 |
prep |
in,reduction |
R3453 |
T11578 |
T11579 |
compound |
cone,function |
R3454 |
T11579 |
T11577 |
pobj |
function,in |
R3455 |
T11580 |
T11572 |
amod |
attributable,reduction |
R3456 |
T11581 |
T11580 |
prep |
to,attributable |
R3457 |
T11582 |
T11583 |
compound |
Rb,loss |
R3458 |
T11583 |
T11581 |
pobj |
loss,to |
R3459 |
T11584 |
T11572 |
amod |
relative,reduction |
R3460 |
T11585 |
T11584 |
prep |
to,relative |
R3461 |
T11586 |
T11585 |
pobj |
WT,to |
R3462 |
T11587 |
T11542 |
punct |
.,attributed |
R3463 |
T11589 |
T11590 |
det |
This,effect |
R3464 |
T11590 |
T11592 |
nsubj |
effect,relate |
R3465 |
T11591 |
T11590 |
amod |
slight,effect |
R3466 |
T11593 |
T11592 |
aux |
may,relate |
R3467 |
T11594 |
T11592 |
prep |
to,relate |
R3468 |
T11595 |
T11596 |
det |
a,defect |
R3469 |
T11596 |
T11594 |
pobj |
defect,to |
R3470 |
T11597 |
T11596 |
amod |
true,defect |
R3471 |
T11598 |
T11596 |
compound |
differentiation,defect |
R3472 |
T11599 |
T11592 |
prep |
in,relate |
R3473 |
T11600 |
T11601 |
det |
a,subset |
R3474 |
T11601 |
T11599 |
pobj |
subset,in |
R3475 |
T11602 |
T11601 |
prep |
of,subset |
R3476 |
T11603 |
T11604 |
amod |
amacrine,cells |
R3477 |
T11604 |
T11602 |
pobj |
cells,of |
R3478 |
T11605 |
T11601 |
acl |
discussed,subset |
R3479 |
T11606 |
T11605 |
advmod |
below,discussed |
R3480 |
T11607 |
T11592 |
punct |
.,relate |
R3481 |
T11609 |
T11610 |
det |
This,discussion |
R3482 |
T11610 |
T11611 |
nsubj |
discussion,obscure |
R3483 |
T11612 |
T11611 |
aux |
should,obscure |
R3484 |
T11613 |
T11611 |
neg |
not,obscure |
R3485 |
T11614 |
T11615 |
det |
the,outcome |
R3486 |
T11615 |
T11611 |
dobj |
outcome,obscure |
R3487 |
T11616 |
T11615 |
amod |
major,outcome |
R3488 |
T11617 |
T11618 |
mark |
that,recovers |
R3489 |
T11618 |
T11615 |
acl |
recovers,outcome |
R3490 |
T11619 |
T11620 |
compound |
E2f1,deletion |
R3491 |
T11620 |
T11618 |
nsubj |
deletion,recovers |
R3492 |
T11621 |
T11618 |
dobj |
most,recovers |
R3493 |
T11622 |
T11621 |
prep |
of,most |
R3494 |
T11623 |
T11624 |
det |
the,response |
R3495 |
T11624 |
T11622 |
pobj |
response,of |
R3496 |
T11625 |
T11624 |
compound |
ERG,response |
R3497 |
T11626 |
T11611 |
punct |
.,obscure |
R3498 |
T11628 |
T11629 |
advmod |
Thus,deletion |
R3499 |
T11630 |
T11629 |
punct |
", ",deletion |
R3500 |
T11631 |
T11629 |
compound |
E2f1,deletion |
R3501 |
T11632 |
T11629 |
preconj |
not,deletion |
R3502 |
T11633 |
T11632 |
advmod |
only,not |
R3503 |
T11634 |
T11629 |
conj |
rescues,deletion |
R3504 |
T11635 |
T11634 |
dobj |
morphology,rescues |
R3505 |
T11636 |
T11635 |
cc |
but,morphology |
R3506 |
T11637 |
T11636 |
advmod |
also,but |
R3507 |
T11638 |
T11639 |
preconj |
both,rod |
R3508 |
T11639 |
T11640 |
nmod |
rod,function |
R3509 |
T11640 |
T11635 |
conj |
function,morphology |
R3510 |
T11641 |
T11639 |
cc |
and,rod |
R3511 |
T11642 |
T11639 |
conj |
cone,rod |
R3512 |
T11643 |
T11640 |
compound |
system,function |
R3513 |
T11644 |
T11634 |
prep |
in,rescues |
R3514 |
T11645 |
T11646 |
det |
the,retina |
R3515 |
T11646 |
T11644 |
pobj |
retina,in |
R3516 |
T11647 |
T11648 |
compound |
Rb,KO |
R3517 |
T11648 |
T11646 |
compound |
KO,retina |
R3518 |
T11649 |
T11634 |
punct |
.,rescues |