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PMC:1892049 / 4453-6058 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T6599 0-10 NN denotes Literature
T6600 11-19 NNS denotes searches
T6601 20-28 VBD denotes revealed
T6602 29-33 IN denotes that
T6604 34-39 IN denotes among
T6605 40-47 NN denotes disease
T6606 48-53 NNS denotes lines
T6607 54-60 VBN denotes mapped
T6608 61-63 IN denotes to
T6609 64-68 NN denotes 6qE1
T6610 68-70 , denotes ,
T6611 70-73 DT denotes the
T6613 74-85 JJ denotes spontaneous
T6612 86-92 NN denotes mutant
T6614 93-96 NN denotes opt
T6615 97-102 NN denotes mouse
T6603 103-111 VBZ denotes displays
T6616 112-113 DT denotes a
T6618 114-124 RB denotes strikingly
T6619 125-132 JJ denotes similar
T6617 133-145 NN denotes presentation
T6620 146-148 IN denotes to
T6621 149-153 DT denotes that
T6622 154-163 VBN denotes described
T6623 164-168 RB denotes here
T6624 169-170 -LRB- denotes [
T6625 170-171 CD denotes 1
T6626 171-172 -RRB- denotes ]
T6627 172-173 . denotes .
T6628 173-374 sentence denotes The underlying genetic lesion causing the opt phenotype is a homozygous in-frame deletion of exons 43 and 44 of the gene Itpr1 (Itpr1opt /opt), encoding inositol 1,4,5-triphosphate receptor 1 (Itpr1).
T6629 174-177 DT denotes The
T6631 178-188 VBG denotes underlying
T6632 189-196 JJ denotes genetic
T6630 197-203 NN denotes lesion
T6634 204-211 VBG denotes causing
T6635 212-215 DT denotes the
T6637 216-219 NN denotes opt
T6636 220-229 NN denotes phenotype
T6633 230-232 VBZ denotes is
T6638 233-234 DT denotes a
T6640 235-245 JJ denotes homozygous
T6641 246-248 IN denotes in
T6643 248-249 HYPH denotes -
T6642 249-254 NN denotes frame
T6639 255-263 NN denotes deletion
T6644 264-266 IN denotes of
T6645 267-272 NNS denotes exons
T6646 273-275 CD denotes 43
T6647 276-279 CC denotes and
T6648 280-282 CD denotes 44
T6649 283-285 IN denotes of
T6650 286-289 DT denotes the
T6652 290-294 NN denotes gene
T6651 295-300 NN denotes Itpr1
T6653 301-302 -LRB- denotes (
T6655 302-310 NN denotes Itpr1opt
T6656 311-312 HYPH denotes /
T6654 312-315 NN denotes opt
T6657 315-316 -RRB- denotes )
T6658 316-318 , denotes ,
T6659 318-326 VBG denotes encoding
T6660 327-335 NN denotes inositol
T6662 336-337 CD denotes 1
T6664 337-338 , denotes ,
T6665 338-339 CD denotes 4
T6666 339-340 , denotes ,
T6663 340-341 CD denotes 5
T6668 341-342 HYPH denotes -
T6667 342-354 NN denotes triphosphate
T6661 355-363 NN denotes receptor
T6669 364-365 CD denotes 1
T6670 366-367 -LRB- denotes (
T6671 367-372 NN denotes Itpr1
T6672 372-373 -RRB- denotes )
T6673 373-374 . denotes .
T6674 374-581 sentence denotes Sequencing of all exons and intron–exon boundaries of Itpr1 in affected mice from the current study revealed a single mutation within Itpr1: a novel in-frame deletion of 18 bp within exon 36 (Itpr1Δ18/Δ18).
T6675 375-385 NN denotes Sequencing
T6677 386-388 IN denotes of
T6678 389-392 DT denotes all
T6679 393-398 NNS denotes exons
T6680 399-402 CC denotes and
T6681 403-409 NN denotes intron
T6683 409-410 HYPH denotes –
T6682 410-414 NN denotes exon
T6684 415-425 NNS denotes boundaries
T6685 426-428 IN denotes of
T6686 429-434 NN denotes Itpr1
T6687 435-437 IN denotes in
T6688 438-446 VBN denotes affected
T6689 447-451 NNS denotes mice
T6690 452-456 IN denotes from
T6691 457-460 DT denotes the
T6693 461-468 JJ denotes current
T6692 469-474 NN denotes study
T6676 475-483 VBD denotes revealed
T6694 484-485 DT denotes a
T6696 486-492 JJ denotes single
T6695 493-501 NN denotes mutation
T6697 502-508 IN denotes within
T6698 509-514 NN denotes Itpr1
T6699 514-516 : denotes :
T6700 516-517 DT denotes a
T6702 518-523 JJ denotes novel
T6703 524-526 IN denotes in
T6704 526-527 HYPH denotes -
T6705 527-532 NN denotes frame
T6701 533-541 NN denotes deletion
T6706 542-544 IN denotes of
T6707 545-547 CD denotes 18
T6708 548-550 NN denotes bp
T6709 551-557 IN denotes within
T6710 558-562 NN denotes exon
T6711 563-565 CD denotes 36
T6712 566-567 -LRB- denotes (
T6714 567-575 NN denotes Itpr1Δ18
T6715 575-576 HYPH denotes /
T6713 576-579 NN denotes Δ18
T6716 579-580 -RRB- denotes )
T6717 580-581 . denotes .
T6718 581-752 sentence denotes To confirm the pathogenicity of this mutation we crossed heterozygous mice from the current study (Itpr1wt/Δ18) with mice heterozygous for the opt mutation (Itpr1wt/opt).
T6719 582-584 TO denotes To
T6720 585-592 VB denotes confirm
T6722 593-596 DT denotes the
T6723 597-610 NN denotes pathogenicity
T6724 611-613 IN denotes of
T6725 614-618 DT denotes this
T6726 619-627 NN denotes mutation
T6727 628-630 PRP denotes we
T6721 631-638 VBD denotes crossed
T6728 639-651 JJ denotes heterozygous
T6729 652-656 NNS denotes mice
T6730 657-661 IN denotes from
T6731 662-665 DT denotes the
T6733 666-673 JJ denotes current
T6732 674-679 NN denotes study
T6734 680-681 -LRB- denotes (
T6736 681-688 NN denotes Itpr1wt
T6737 688-689 HYPH denotes /
T6735 689-692 NN denotes Δ18
T6738 692-693 -RRB- denotes )
T6739 694-698 IN denotes with
T6740 699-703 NNS denotes mice
T6741 704-716 JJ denotes heterozygous
T6742 717-720 IN denotes for
T6743 721-724 DT denotes the
T6745 725-728 NN denotes opt
T6744 729-737 NN denotes mutation
T6746 738-739 -LRB- denotes (
T6748 739-746 NN denotes Itpr1wt
T6749 746-747 HYPH denotes /
T6747 747-750 NN denotes opt
T6750 750-751 -RRB- denotes )
T6751 751-752 . denotes .
T6752 752-951 sentence denotes This resulted in two litters of mice with a total of four affected Itpr1opt/Δ18 pups (from a total of 15) with a phenotype indistinguishable from that of the Itpr1Δ18/Δ18 and Itpr1opt /opt mice [1].
T6753 753-757 DT denotes This
T6754 758-766 VBD denotes resulted
T6755 767-769 IN denotes in
T6756 770-773 CD denotes two
T6757 774-781 NNS denotes litters
T6758 782-784 IN denotes of
T6759 785-789 NNS denotes mice
T6760 790-794 IN denotes with
T6761 795-796 DT denotes a
T6762 797-802 NN denotes total
T6763 803-805 IN denotes of
T6764 806-810 CD denotes four
T6766 811-819 VBN denotes affected
T6767 820-828 NN denotes Itpr1opt
T6769 828-829 HYPH denotes /
T6768 829-832 NN denotes Δ18
T6765 833-837 NNS denotes pups
T6770 838-839 -LRB- denotes (
T6771 839-843 IN denotes from
T6772 844-845 DT denotes a
T6773 846-851 NN denotes total
T6774 852-854 IN denotes of
T6775 855-857 CD denotes 15
T6776 857-858 -RRB- denotes )
T6777 859-863 IN denotes with
T6778 864-865 DT denotes a
T6779 866-875 NN denotes phenotype
T6780 876-893 JJ denotes indistinguishable
T6781 894-898 IN denotes from
T6782 899-903 DT denotes that
T6783 904-906 IN denotes of
T6784 907-910 DT denotes the
T6786 911-919 NN denotes Itpr1Δ18
T6788 919-920 HYPH denotes /
T6787 920-923 NN denotes Δ18
T6789 924-927 CC denotes and
T6790 928-936 NN denotes Itpr1opt
T6792 937-938 HYPH denotes /
T6791 938-941 NN denotes opt
T6785 942-946 NNS denotes mice
T6793 947-948 -LRB- denotes [
T6794 948-949 CD denotes 1
T6795 949-950 -RRB- denotes ]
T6796 950-951 . denotes .
T6797 951-1136 sentence denotes Furthermore, this phenotype was similar, although less severe, to that described in a mouse line with targeted deletion of Itpr1, where ataxia was described as a prominent feature [4].
T6798 952-963 RB denotes Furthermore
T6800 963-965 , denotes ,
T6801 965-969 DT denotes this
T6802 970-979 NN denotes phenotype
T6799 980-983 VBD denotes was
T6803 984-991 JJ denotes similar
T6804 991-993 , denotes ,
T6805 993-1001 IN denotes although
T6807 1002-1006 RBR denotes less
T6806 1007-1013 JJ denotes severe
T6808 1013-1015 , denotes ,
T6809 1015-1017 IN denotes to
T6810 1018-1022 DT denotes that
T6811 1023-1032 VBN denotes described
T6812 1033-1035 IN denotes in
T6813 1036-1037 DT denotes a
T6815 1038-1043 NN denotes mouse
T6814 1044-1048 NN denotes line
T6816 1049-1053 IN denotes with
T6817 1054-1062 VBN denotes targeted
T6818 1063-1071 NN denotes deletion
T6819 1072-1074 IN denotes of
T6820 1075-1080 NN denotes Itpr1
T6821 1080-1082 , denotes ,
T6822 1082-1087 WRB denotes where
T6824 1088-1094 NN denotes ataxia
T6825 1095-1098 VBD denotes was
T6823 1099-1108 VBN denotes described
T6826 1109-1111 IN denotes as
T6827 1112-1113 DT denotes a
T6829 1114-1123 JJ denotes prominent
T6828 1124-1131 NN denotes feature
T6830 1132-1133 -LRB- denotes [
T6831 1133-1134 CD denotes 4
T6832 1134-1135 -RRB- denotes ]
T6833 1135-1136 . denotes .
T6834 1136-1397 sentence denotes As with the Itpr1opt /opt mice, where the deletion of exons 43 and 44 is also predicted to leave the translational reading frame unaffected, the in-frame Itpr1Δ18/Δ18 deletion mutation results in markedly decreased levels of Itpr1 in cerebellar Purkinje cells.
T6835 1137-1139 IN denotes As
T6837 1140-1144 IN denotes with
T6838 1145-1148 DT denotes the
T6840 1149-1157 NN denotes Itpr1opt
T6842 1158-1159 HYPH denotes /
T6841 1159-1162 NN denotes opt
T6839 1163-1167 NNS denotes mice
T6843 1167-1169 , denotes ,
T6844 1169-1174 WRB denotes where
T6846 1175-1178 DT denotes the
T6847 1179-1187 NN denotes deletion
T6848 1188-1190 IN denotes of
T6849 1191-1196 NNS denotes exons
T6850 1197-1199 CD denotes 43
T6851 1200-1203 CC denotes and
T6852 1204-1206 CD denotes 44
T6853 1207-1209 VBZ denotes is
T6854 1210-1214 RB denotes also
T6845 1215-1224 VBN denotes predicted
T6855 1225-1227 TO denotes to
T6856 1228-1233 VB denotes leave
T6857 1234-1237 DT denotes the
T6859 1238-1251 JJ denotes translational
T6860 1252-1259 NN denotes reading
T6858 1260-1265 NN denotes frame
T6861 1266-1276 JJ denotes unaffected
T6862 1276-1278 , denotes ,
T6863 1278-1281 DT denotes the
T6865 1282-1284 IN denotes in
T6866 1284-1285 HYPH denotes -
T6867 1285-1290 NN denotes frame
T6868 1291-1299 NN denotes Itpr1Δ18
T6870 1299-1300 HYPH denotes /
T6869 1300-1303 NN denotes Δ18
T6871 1304-1312 NN denotes deletion
T6864 1313-1321 NN denotes mutation
T6836 1322-1329 VBZ denotes results
T6872 1330-1332 IN denotes in
T6873 1333-1341 RB denotes markedly
T6874 1342-1351 VBN denotes decreased
T6875 1352-1358 NNS denotes levels
T6876 1359-1361 IN denotes of
T6877 1362-1367 NN denotes Itpr1
T6878 1368-1370 IN denotes in
T6879 1371-1381 JJ denotes cerebellar
T6881 1382-1390 NNP denotes Purkinje
T6880 1391-1396 NNS denotes cells
T6882 1396-1397 . denotes .
T6883 1397-1605 sentence denotes In these two spontaneous mutants [1] and in the Itpr1-deficient mouse [4] generated by gene targeting, decreased Itpr1 expression is associated with the same autosomal recessive movement disorder (Figure 1).
T6884 1398-1400 IN denotes In
T6886 1401-1406 DT denotes these
T6888 1407-1410 CD denotes two
T6889 1411-1422 JJ denotes spontaneous
T6887 1423-1430 NNS denotes mutants
T6890 1431-1432 -LRB- denotes [
T6891 1432-1433 CD denotes 1
T6892 1433-1434 -RRB- denotes ]
T6893 1435-1438 CC denotes and
T6894 1439-1441 IN denotes in
T6895 1442-1445 DT denotes the
T6897 1446-1451 NN denotes Itpr1
T6899 1451-1452 HYPH denotes -
T6898 1452-1461 JJ denotes deficient
T6896 1462-1467 NN denotes mouse
T6900 1468-1469 -LRB- denotes [
T6901 1469-1470 CD denotes 4
T6902 1470-1471 -RRB- denotes ]
T6903 1472-1481 VBN denotes generated
T6904 1482-1484 IN denotes by
T6905 1485-1489 NN denotes gene
T6906 1490-1499 NN denotes targeting
T6907 1499-1501 , denotes ,
T6908 1501-1510 VBN denotes decreased
T6910 1511-1516 NN denotes Itpr1
T6909 1517-1527 NN denotes expression
T6911 1528-1530 VBZ denotes is
T6885 1531-1541 VBN denotes associated
T6912 1542-1546 IN denotes with
T6913 1547-1550 DT denotes the
T6915 1551-1555 JJ denotes same
T6916 1556-1565 JJ denotes autosomal
T6917 1566-1575 JJ denotes recessive
T6918 1576-1584 NN denotes movement
T6914 1585-1593 NN denotes disorder
T6919 1594-1595 -LRB- denotes (
T6920 1595-1601 NN denotes Figure
T6921 1602-1603 CD denotes 1
T6922 1603-1604 -RRB- denotes )
T6923 1604-1605 . denotes .
R1000 T6861 T6856 oprd unaffected,leave
R1003 T6862 T6836 punct ", ",results
R1007 T6863 T6864 det the,mutation
R1010 T6864 T6836 nsubj mutation,results
R1013 T6865 T6864 nmod in,mutation
R1016 T6866 T6865 punct -,in
R1020 T6867 T6865 pobj frame,in
R1027 T6868 T6869 compound Itpr1Δ18,Δ18
R1031 T6869 T6864 compound Δ18,mutation
R1035 T6870 T6869 punct /,Δ18
R1038 T6871 T6864 compound deletion,mutation
R1042 T6872 T6836 prep in,results
R1046 T6873 T6874 advmod markedly,decreased
R1050 T6874 T6875 amod decreased,levels
R1054 T6875 T6872 pobj levels,in
R1058 T6876 T6875 prep of,levels
R1062 T6877 T6876 pobj Itpr1,of
R1066 T6878 T6836 prep in,results
R1068 T6879 T6880 amod cerebellar,cells
R1071 T6880 T6878 pobj cells,in
R1078 T6881 T6880 compound Purkinje,cells
R1082 T6882 T6836 punct .,results
R1086 T6884 T6885 prep In,associated
R1091 T6886 T6887 det these,mutants
R1096 T6887 T6884 pobj mutants,In
R1097 T6888 T6887 nummod two,mutants
R1100 T6889 T6887 amod spontaneous,mutants
R1103 T6890 T6891 punct [,1
R1104 T6891 T6887 parataxis 1,mutants
R1105 T6892 T6891 punct ],1
R1109 T6893 T6884 cc and,In
R1111 T6894 T6884 conj in,In
R576 T6599 T6600 compound Literature,searches
R577 T6600 T6601 nsubj searches,revealed
R579 T6602 T6603 mark that,displays
R581 T6603 T6601 ccomp displays,revealed
R582 T6604 T6603 prep among,displays
R583 T6605 T6606 compound disease,lines
R585 T6606 T6604 pobj lines,among
R586 T6607 T6606 acl mapped,lines
R587 T6608 T6607 prep to,mapped
R589 T6609 T6608 pobj 6qE1,to
R590 T6610 T6603 punct ", ",displays
R592 T6611 T6612 det the,mutant
R593 T6612 T6603 nsubj mutant,displays
R594 T6613 T6612 amod spontaneous,mutant
R596 T6614 T6615 compound opt,mouse
R597 T6615 T6612 appos mouse,mutant
R598 T6616 T6617 det a,presentation
R599 T6617 T6603 dobj presentation,displays
R601 T6618 T6619 advmod strikingly,similar
R602 T6619 T6617 amod similar,presentation
R604 T6620 T6617 prep to,presentation
R605 T6621 T6620 pobj that,to
R606 T6622 T6621 acl described,that
R607 T6623 T6622 advmod here,described
R609 T6624 T6625 punct [,1
R610 T6625 T6601 parataxis 1,revealed
R611 T6626 T6625 punct ],1
R612 T6627 T6601 punct .,revealed
R615 T6629 T6630 det The,lesion
R616 T6630 T6633 nsubj lesion,is
R617 T6631 T6630 amod underlying,lesion
R618 T6632 T6630 amod genetic,lesion
R620 T6634 T6630 acl causing,lesion
R622 T6635 T6636 det the,phenotype
R623 T6636 T6634 dobj phenotype,causing
R624 T6637 T6636 compound opt,phenotype
R626 T6638 T6639 det a,deletion
R627 T6639 T6633 attr deletion,is
R628 T6640 T6639 amod homozygous,deletion
R629 T6641 T6642 nmod in,frame
R631 T6642 T6639 compound frame,deletion
R632 T6643 T6642 punct -,frame
R634 T6644 T6639 prep of,deletion
R635 T6645 T6646 nmod exons,43
R636 T6646 T6644 pobj 43,of
R638 T6647 T6646 cc and,43
R639 T6648 T6646 conj 44,43
R640 T6649 T6646 prep of,43
R642 T6650 T6651 det the,Itpr1
R643 T6651 T6649 pobj Itpr1,of
R644 T6652 T6651 compound gene,Itpr1
R646 T6653 T6654 punct (,opt
R647 T6654 T6651 parataxis opt,Itpr1
R648 T6655 T6654 compound Itpr1opt,opt
R650 T6656 T6654 punct /,opt
R651 T6657 T6654 punct ),opt
R652 T6658 T6646 punct ", ",43
R653 T6659 T6646 acl encoding,43
R655 T6660 T6661 nmod inositol,receptor
R656 T6661 T6659 dobj receptor,encoding
R657 T6662 T6663 nummod 1,5
R658 T6663 T6667 nummod 5,triphosphate
R659 T6664 T6663 punct ",",5
R660 T6665 T6663 nummod 4,5
R661 T6666 T6663 punct ",",5
R662 T6667 T6661 compound triphosphate,receptor
R663 T6668 T6667 punct -,triphosphate
R665 T6669 T6661 nummod 1,receptor
R666 T6670 T6671 punct (,Itpr1
R667 T6671 T6661 parataxis Itpr1,receptor
R669 T6672 T6671 punct ),Itpr1
R670 T6673 T6633 punct .,is
R672 T6675 T6676 nsubj Sequencing,revealed
R674 T6677 T6675 prep of,Sequencing
R676 T6678 T6679 det all,exons
R677 T6679 T6677 pobj exons,of
R679 T6680 T6679 cc and,exons
R680 T6681 T6682 compound intron,exon
R681 T6682 T6684 compound exon,boundaries
R683 T6683 T6682 punct –,exon
R686 T6684 T6679 conj boundaries,exons
R688 T6685 T6684 prep of,boundaries
R689 T6686 T6685 pobj Itpr1,of
R691 T6687 T6679 prep in,exons
R692 T6688 T6689 amod affected,mice
R694 T6689 T6687 pobj mice,in
R695 T6690 T6689 prep from,mice
R697 T6691 T6692 det the,study
R698 T6692 T6690 pobj study,from
R699 T6693 T6692 amod current,study
R701 T6694 T6695 det a,mutation
R702 T6695 T6676 dobj mutation,revealed
R703 T6696 T6695 amod single,mutation
R705 T6697 T6695 prep within,mutation
R706 T6698 T6697 pobj Itpr1,within
R707 T6699 T6695 punct : ,mutation
R709 T6700 T6701 det a,deletion
R710 T6701 T6695 appos deletion,mutation
R711 T6702 T6701 amod novel,deletion
R712 T6703 T6701 nmod in,deletion
R713 T6704 T6703 punct -,in
R714 T6705 T6703 pobj frame,in
R716 T6706 T6701 prep of,deletion
R717 T6707 T6708 nummod 18,bp
R718 T6708 T6706 pobj bp,of
R720 T6709 T6701 prep within,deletion
R722 T6710 T6709 pobj exon,within
R723 T6711 T6710 nummod 36,exon
R724 T6712 T6713 punct (,Δ18
R725 T6713 T6701 parataxis Δ18,deletion
R727 T6714 T6713 compound Itpr1Δ18,Δ18
R728 T6715 T6713 punct /,Δ18
R729 T6716 T6713 punct ),Δ18
R731 T6717 T6676 punct .,revealed
R732 T6719 T6720 aux To,confirm
R734 T6720 T6721 advcl confirm,crossed
R735 T6722 T6723 det the,pathogenicity
R737 T6723 T6720 dobj pathogenicity,confirm
R738 T6724 T6723 prep of,pathogenicity
R739 T6725 T6726 det this,mutation
R741 T6726 T6724 pobj mutation,of
R742 T6727 T6721 nsubj we,crossed
R744 T6728 T6729 amod heterozygous,mice
R745 T6729 T6721 dobj mice,crossed
R746 T6730 T6729 prep from,mice
R747 T6731 T6732 det the,study
R749 T6732 T6730 pobj study,from
R750 T6733 T6732 amod current,study
R752 T6734 T6735 punct (,Δ18
R753 T6735 T6730 parataxis Δ18,from
R754 T6736 T6735 compound Itpr1wt,Δ18
R755 T6737 T6735 punct /,Δ18
R757 T6738 T6735 punct ),Δ18
R758 T6739 T6721 prep with,crossed
R759 T6789 T6787 cc and,Δ18
R760 T6740 T6739 pobj mice,with
R761 T6741 T6740 amod heterozygous,mice
R762 T6742 T6741 prep for,heterozygous
R763 T6743 T6744 det the,mutation
R764 T6744 T6742 pobj mutation,for
R765 T6745 T6744 compound opt,mutation
R766 T6746 T6747 punct (,opt
R767 T6747 T6740 parataxis opt,mice
R768 T6748 T6747 compound Itpr1wt,opt
R769 T6749 T6747 punct /,opt
R770 T6790 T6791 compound Itpr1opt,opt
R771 T6750 T6747 punct ),opt
R772 T6751 T6721 punct .,crossed
R773 T6791 T6787 conj opt,Δ18
R774 T6753 T6754 nsubj This,resulted
R775 T6755 T6754 prep in,resulted
R776 T6792 T6791 punct /,opt
R777 T6756 T6757 nummod two,litters
R778 T6757 T6755 pobj litters,in
R779 T6758 T6757 prep of,litters
R780 T6793 T6794 punct [,1
R781 T6759 T6758 pobj mice,of
R782 T6760 T6757 prep with,litters
R783 T6761 T6762 det a,total
R784 T6794 T6754 parataxis 1,resulted
R785 T6762 T6760 pobj total,with
R786 T6795 T6794 punct ],1
R787 T6763 T6762 prep of,total
R788 T6796 T6754 punct .,resulted
R789 T6764 T6765 nummod four,pups
R790 T6765 T6763 pobj pups,of
R791 T6766 T6765 amod affected,pups
R792 T6798 T6799 advmod Furthermore,was
R793 T6767 T6768 compound Itpr1opt,Δ18
R794 T6768 T6765 compound Δ18,pups
R795 T6769 T6768 punct /,Δ18
R796 T6770 T6762 punct (,total
R797 T6800 T6799 punct ", ",was
R798 T6771 T6762 prep from,total
R799 T6772 T6773 det a,total
R800 T6773 T6771 pobj total,from
R801 T6801 T6802 det this,phenotype
R802 T6774 T6773 prep of,total
R803 T6775 T6774 pobj 15,of
R804 T6776 T6762 punct ),total
R805 T6802 T6799 nsubj phenotype,was
R806 T6777 T6762 prep with,total
R807 T6778 T6779 det a,phenotype
R808 T6779 T6777 pobj phenotype,with
R809 T6803 T6799 acomp similar,was
R810 T6780 T6779 amod indistinguishable,phenotype
R811 T6781 T6780 prep from,indistinguishable
R812 T6782 T6781 pobj that,from
R813 T6783 T6782 prep of,that
R814 T6784 T6785 det the,mice
R815 T6785 T6783 pobj mice,of
R816 T6804 T6799 punct ", ",was
R817 T6786 T6787 nmod Itpr1Δ18,Δ18
R818 T6787 T6785 nmod Δ18,mice
R819 T6788 T6787 punct /,Δ18
R820 T6805 T6806 mark although,severe
R821 T6806 T6799 advcl severe,was
R822 T6807 T6806 advmod less,severe
R823 T6895 T6896 det the,mouse
R824 T6808 T6799 punct ", ",was
R825 T6896 T6894 pobj mouse,in
R826 T6897 T6898 npadvmod Itpr1,deficient
R827 T6898 T6896 amod deficient,mouse
R828 T6809 T6799 prep to,was
R829 T6899 T6898 punct -,deficient
R830 T6810 T6809 pobj that,to
R831 T6900 T6901 punct [,4
R832 T6901 T6896 parataxis 4,mouse
R833 T6902 T6901 punct ],4
R834 T6811 T6810 acl described,that
R835 T6903 T6896 acl generated,mouse
R836 T6904 T6903 prep by,generated
R837 T6905 T6906 compound gene,targeting
R838 T6906 T6904 pobj targeting,by
R839 T6812 T6811 prep in,described
R840 T6907 T6885 punct ", ",associated
R841 T6908 T6909 amod decreased,expression
R842 T6813 T6814 det a,line
R843 T6909 T6885 nsubjpass expression,associated
R844 T6910 T6909 compound Itpr1,expression
R845 T6911 T6885 auxpass is,associated
R846 T6814 T6812 pobj line,in
R847 T6912 T6885 prep with,associated
R848 T6913 T6914 det the,disorder
R849 T6914 T6912 pobj disorder,with
R850 T6915 T6914 amod same,disorder
R851 T6815 T6814 compound mouse,line
R852 T6916 T6914 amod autosomal,disorder
R853 T6917 T6914 amod recessive,disorder
R854 T6816 T6814 prep with,line
R855 T6918 T6914 compound movement,disorder
R856 T6919 T6920 punct (,Figure
R857 T6920 T6885 parataxis Figure,associated
R858 T6921 T6920 nummod 1,Figure
R859 T6817 T6818 amod targeted,deletion
R860 T6922 T6920 punct ),Figure
R861 T6923 T6885 punct .,associated
R862 T6818 T6816 pobj deletion,with
R868 T6819 T6818 prep of,deletion
R871 T6820 T6819 pobj Itpr1,of
R872 T6821 T6820 punct ", ",Itpr1
R875 T6822 T6823 advmod where,described
R876 T6823 T6820 relcl described,Itpr1
R878 T6824 T6823 nsubjpass ataxia,described
R881 T6825 T6823 auxpass was,described
R884 T6826 T6823 prep as,described
R886 T6827 T6828 det a,feature
R890 T6828 T6826 pobj feature,as
R893 T6829 T6828 amod prominent,feature
R897 T6830 T6831 punct [,4
R901 T6831 T6799 parataxis 4,was
R905 T6832 T6831 punct ],4
R908 T6833 T6799 punct .,was
R912 T6835 T6836 prep As,results
R916 T6837 T6835 prep with,As
R923 T6838 T6839 det the,mice
R927 T6839 T6837 pobj mice,with
R931 T6840 T6841 compound Itpr1opt,opt
R934 T6841 T6839 compound opt,mice
R937 T6842 T6841 punct /,opt
R940 T6843 T6839 punct ", ",mice
R944 T6844 T6845 advmod where,predicted
R948 T6845 T6839 relcl predicted,mice
R952 T6846 T6847 det the,deletion
R955 T6847 T6845 nsubjpass deletion,predicted
R959 T6848 T6847 prep of,deletion
R962 T6849 T6850 nmod exons,43
R963 T6850 T6848 pobj 43,of
R965 T6851 T6850 cc and,43
R972 T6852 T6850 conj 44,43
R976 T6853 T6845 auxpass is,predicted
R980 T6854 T6845 advmod also,predicted
R984 T6855 T6856 aux to,leave
R986 T6856 T6845 xcomp leave,predicted
R987 T6857 T6858 det the,frame
R990 T6858 T6856 dobj frame,leave
R993 T6859 T6858 amod translational,frame
R996 T6860 T6858 compound reading,frame