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PMC:1860061 / 19059-19981 JSONTXT 5 Projects

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Id Subject Object Predicate Lexical cue
T13481 0-2 IN denotes In
T13483 3-7 DT denotes this
T13484 8-13 NN denotes study
T13485 13-15 , denotes ,
T13486 15-17 PRP denotes we
T13482 18-27 VBD denotes attempted
T13487 28-31 IN denotes for
T13488 32-35 DT denotes the
T13490 36-41 JJ denotes first
T13489 42-46 NN denotes time
T13491 47-49 TO denotes to
T13492 50-58 VB denotes identify
T13493 59-64 JJ denotes small
T13495 64-65 HYPH denotes -
T13494 65-71 NN denotes effect
T13496 72-75 NNS denotes QTL
T13497 76-78 IN denotes in
T13498 79-81 DT denotes an
T13500 82-84 NN denotes F2
T13499 85-92 NN denotes progeny
T13501 92-93 . denotes .
T13502 93-266 sentence denotes Small-effect QTL are defined as those reaching the threshold value of P = 0.05 but that did not reach the significant threshold value suggested by Lander and Botstein [26].
T13503 94-99 JJ denotes Small
T13505 99-100 HYPH denotes -
T13504 100-106 NN denotes effect
T13506 107-110 NNS denotes QTL
T13508 111-114 VBP denotes are
T13507 115-122 VBN denotes defined
T13509 123-125 IN denotes as
T13510 126-131 DT denotes those
T13511 132-140 VBG denotes reaching
T13512 141-144 DT denotes the
T13514 145-154 NN denotes threshold
T13513 155-160 NN denotes value
T13515 161-163 IN denotes of
T13516 164-165 NN denotes P
T13518 166-167 SYM denotes =
T13517 168-172 CD denotes 0.05
T13519 173-176 CC denotes but
T13520 177-181 DT denotes that
T13522 182-185 VBD denotes did
T13523 186-189 RB denotes not
T13521 190-195 VB denotes reach
T13524 196-199 DT denotes the
T13526 200-211 JJ denotes significant
T13527 212-221 NN denotes threshold
T13525 222-227 NN denotes value
T13528 228-237 VBN denotes suggested
T13529 238-240 IN denotes by
T13530 241-247 NNP denotes Lander
T13531 248-251 CC denotes and
T13532 252-260 NNP denotes Botstein
T13533 261-262 -LRB- denotes [
T13534 262-264 CD denotes 26
T13535 264-265 -RRB- denotes ]
T13536 265-266 . denotes .
T13537 266-395 sentence denotes Although not significant, there is evidence that most of the eight small-effect QTL likely contain susceptibility genes for CIA.
T13538 267-275 IN denotes Although
T13540 276-279 RB denotes not
T13539 280-291 JJ denotes significant
T13542 291-293 , denotes ,
T13543 293-298 EX denotes there
T13541 299-301 VBZ denotes is
T13544 302-310 NN denotes evidence
T13545 311-315 IN denotes that
T13547 316-320 JJS denotes most
T13548 321-323 IN denotes of
T13549 324-327 DT denotes the
T13551 328-333 CD denotes eight
T13552 334-339 JJ denotes small
T13554 339-340 HYPH denotes -
T13553 340-346 NN denotes effect
T13550 347-350 NNS denotes QTL
T13555 351-357 RB denotes likely
T13546 358-365 VBP denotes contain
T13556 366-380 NN denotes susceptibility
T13557 381-386 NNS denotes genes
T13558 387-390 IN denotes for
T13559 391-394 NN denotes CIA
T13560 394-395 . denotes .
T13561 395-530 sentence denotes First, we performed the linkage analysis in three datasets, including all 290 F progeny, 76 C5+/+ F2 progeny and 133 C5+/- F2 progeny.
T13562 396-401 RB denotes First
T13564 401-403 , denotes ,
T13565 403-405 PRP denotes we
T13563 406-415 VBD denotes performed
T13566 416-419 DT denotes the
T13568 420-427 NN denotes linkage
T13567 428-436 NN denotes analysis
T13569 437-439 IN denotes in
T13570 440-445 CD denotes three
T13571 446-454 NNS denotes datasets
T13572 454-456 , denotes ,
T13573 456-465 VBG denotes including
T13574 466-469 DT denotes all
T13576 470-473 CD denotes 290
T13577 474-475 NN denotes F
T13575 476-483 NN denotes progeny
T13578 483-485 , denotes ,
T13579 485-487 CD denotes 76
T13581 488-491 NN denotes C5+
T13582 491-492 HYPH denotes /
T13583 492-493 SYM denotes +
T13584 494-496 NN denotes F2
T13580 497-504 NN denotes progeny
T13585 505-508 CC denotes and
T13586 509-512 CD denotes 133
T13588 513-516 NN denotes C5+
T13589 516-517 HYPH denotes /
T13590 517-518 SYM denotes -
T13591 519-521 NN denotes F2
T13587 522-529 NN denotes progeny
T13592 529-530 . denotes .
T13593 530-651 sentence denotes Five of the eight small-effect QTL were identified in at least two datasets, suggesting that these QTL are reproducible.
T13594 531-535 CD denotes Five
T13596 536-538 IN denotes of
T13597 539-542 DT denotes the
T13595 543-548 CD denotes eight
T13599 549-554 JJ denotes small
T13601 554-555 HYPH denotes -
T13600 555-561 NN denotes effect
T13598 562-565 NNS denotes QTL
T13603 566-570 VBD denotes were
T13602 571-581 VBN denotes identified
T13604 582-584 IN denotes in
T13605 585-587 RB denotes at
T13607 588-593 RBS denotes least
T13606 594-597 CD denotes two
T13608 598-606 NNS denotes datasets
T13609 606-608 , denotes ,
T13610 608-618 VBG denotes suggesting
T13611 619-623 IN denotes that
T13613 624-629 DT denotes these
T13614 630-633 NNS denotes QTL
T13612 634-637 VBP denotes are
T13615 638-650 JJ denotes reproducible
T13616 650-651 . denotes .
T13617 651-780 sentence denotes Second, many QTL identified in the present study overlap with arthritis QTL previously identified, including loci 1, 2, 5 and 6.
T13618 652-658 RB denotes Second
T13620 658-660 , denotes ,
T13621 660-664 JJ denotes many
T13622 665-668 NNS denotes QTL
T13623 669-679 VBN denotes identified
T13624 680-682 IN denotes in
T13625 683-686 DT denotes the
T13627 687-694 JJ denotes present
T13626 695-700 NN denotes study
T13619 701-708 VBP denotes overlap
T13628 709-713 IN denotes with
T13629 714-723 NN denotes arthritis
T13630 724-727 NNS denotes QTL
T13631 728-738 RB denotes previously
T13632 739-749 VBN denotes identified
T13633 749-751 , denotes ,
T13634 751-760 VBG denotes including
T13635 761-765 NNS denotes loci
T13636 766-767 CD denotes 1
T13637 767-769 , denotes ,
T13638 769-770 CD denotes 2
T13639 770-772 , denotes ,
T13640 772-773 CD denotes 5
T13641 774-777 CC denotes and
T13642 778-779 CD denotes 6
T13643 779-780 . denotes .
T13644 780-922 sentence denotes In addition, syntenic analysis revealed that the counterpart genomic regions on the human genome of many of these eight QTL are linked to RA.
T13645 781-783 IN denotes In
T13647 784-792 NN denotes addition
T13648 792-794 , denotes ,
T13649 794-802 JJ denotes syntenic
T13650 803-811 NN denotes analysis
T13646 812-820 VBD denotes revealed
T13651 821-825 IN denotes that
T13653 826-829 DT denotes the
T13655 830-841 NN denotes counterpart
T13656 842-849 JJ denotes genomic
T13654 850-857 NNS denotes regions
T13657 858-860 IN denotes on
T13658 861-864 DT denotes the
T13660 865-870 JJ denotes human
T13659 871-877 NN denotes genome
T13661 878-880 IN denotes of
T13662 881-885 JJ denotes many
T13663 886-888 IN denotes of
T13664 889-894 DT denotes these
T13666 895-900 CD denotes eight
T13665 901-904 NNS denotes QTL
T13667 905-908 VBP denotes are
T13652 909-915 VBN denotes linked
T13668 916-918 IN denotes to
T13669 919-921 NN denotes RA
T13670 921-922 . denotes .
R3525 T13481 T13482 prep In,attempted
R3526 T13483 T13484 det this,study
R3527 T13484 T13481 pobj study,In
R3528 T13485 T13482 punct ", ",attempted
R3529 T13486 T13482 nsubj we,attempted
R3530 T13487 T13482 prep for,attempted
R3531 T13488 T13489 det the,time
R3532 T13489 T13487 pobj time,for
R3533 T13490 T13489 amod first,time
R3534 T13491 T13492 aux to,identify
R3535 T13492 T13482 xcomp identify,attempted
R3536 T13493 T13494 amod small,effect
R3537 T13494 T13496 compound effect,QTL
R3538 T13495 T13494 punct -,effect
R3539 T13496 T13492 dobj QTL,identify
R3540 T13497 T13492 prep in,identify
R3541 T13498 T13499 det an,progeny
R3542 T13499 T13497 pobj progeny,in
R3543 T13500 T13499 compound F2,progeny
R3544 T13501 T13482 punct .,attempted
R3545 T13503 T13504 amod Small,effect
R3546 T13504 T13506 compound effect,QTL
R3547 T13505 T13504 punct -,effect
R3548 T13506 T13507 nsubjpass QTL,defined
R3549 T13508 T13507 auxpass are,defined
R3550 T13509 T13507 prep as,defined
R3551 T13510 T13509 pobj those,as
R3552 T13511 T13510 acl reaching,those
R3553 T13512 T13513 det the,value
R3554 T13513 T13511 dobj value,reaching
R3555 T13514 T13513 compound threshold,value
R3556 T13515 T13513 prep of,value
R3557 T13516 T13517 nsubj P,0.05
R3558 T13517 T13515 pcomp 0.05,of
R3559 T13518 T13517 punct =,0.05
R3560 T13519 T13507 cc but,defined
R3561 T13520 T13521 nsubj that,reach
R3562 T13521 T13507 conj reach,defined
R3563 T13522 T13521 aux did,reach
R3564 T13523 T13521 neg not,reach
R3565 T13524 T13525 det the,value
R3566 T13525 T13521 dobj value,reach
R3567 T13526 T13527 amod significant,threshold
R3568 T13527 T13525 compound threshold,value
R3569 T13528 T13525 acl suggested,value
R3570 T13529 T13528 agent by,suggested
R3571 T13530 T13529 pobj Lander,by
R3572 T13531 T13530 cc and,Lander
R3573 T13532 T13530 conj Botstein,Lander
R3574 T13533 T13534 punct [,26
R3575 T13534 T13528 parataxis 26,suggested
R3576 T13535 T13534 punct ],26
R3577 T13536 T13521 punct .,reach
R3578 T13538 T13539 mark Although,significant
R3579 T13539 T13541 advcl significant,is
R3580 T13540 T13539 neg not,significant
R3581 T13542 T13541 punct ", ",is
R3582 T13543 T13541 expl there,is
R3583 T13544 T13541 attr evidence,is
R3584 T13545 T13546 mark that,contain
R3585 T13546 T13544 acl contain,evidence
R3586 T13547 T13546 nsubj most,contain
R3587 T13548 T13547 prep of,most
R3588 T13549 T13550 det the,QTL
R3589 T13550 T13548 pobj QTL,of
R3590 T13551 T13550 nummod eight,QTL
R3591 T13552 T13553 amod small,effect
R3592 T13553 T13550 compound effect,QTL
R3593 T13554 T13553 punct -,effect
R3594 T13555 T13546 advmod likely,contain
R3595 T13556 T13557 compound susceptibility,genes
R3596 T13557 T13546 dobj genes,contain
R3597 T13558 T13557 prep for,genes
R3598 T13559 T13558 pobj CIA,for
R3599 T13560 T13541 punct .,is
R3600 T13562 T13563 advmod First,performed
R3601 T13564 T13563 punct ", ",performed
R3602 T13565 T13563 nsubj we,performed
R3603 T13566 T13567 det the,analysis
R3604 T13567 T13563 dobj analysis,performed
R3605 T13568 T13567 compound linkage,analysis
R3606 T13569 T13563 prep in,performed
R3607 T13570 T13571 nummod three,datasets
R3608 T13571 T13569 pobj datasets,in
R3609 T13572 T13571 punct ", ",datasets
R3610 T13573 T13571 prep including,datasets
R3611 T13574 T13575 det all,progeny
R3612 T13575 T13573 pobj progeny,including
R3613 T13576 T13575 nummod 290,progeny
R3614 T13577 T13575 compound F,progeny
R3615 T13578 T13575 punct ", ",progeny
R3616 T13579 T13580 nummod 76,progeny
R3617 T13580 T13575 conj progeny,progeny
R3618 T13581 T13580 nmod C5+,progeny
R3619 T13582 T13581 punct /,C5+
R3620 T13583 T13581 punct +,C5+
R3621 T13584 T13580 compound F2,progeny
R3622 T13585 T13580 cc and,progeny
R3623 T13586 T13587 nummod 133,progeny
R3624 T13587 T13580 conj progeny,progeny
R3625 T13588 T13587 nmod C5+,progeny
R3626 T13589 T13588 punct /,C5+
R3627 T13590 T13588 punct -,C5+
R3628 T13591 T13587 compound F2,progeny
R3629 T13592 T13563 punct .,performed
R3630 T13594 T13595 quantmod Five,eight
R3631 T13595 T13598 nummod eight,QTL
R3632 T13596 T13595 quantmod of,eight
R3633 T13597 T13595 quantmod the,eight
R3634 T13598 T13602 nsubjpass QTL,identified
R3635 T13599 T13600 amod small,effect
R3636 T13600 T13598 compound effect,QTL
R3637 T13601 T13600 punct -,effect
R3638 T13603 T13602 auxpass were,identified
R3639 T13604 T13602 prep in,identified
R3640 T13605 T13606 advmod at,two
R3641 T13606 T13608 nummod two,datasets
R3642 T13607 T13606 advmod least,two
R3643 T13608 T13604 pobj datasets,in
R3644 T13609 T13602 punct ", ",identified
R3645 T13610 T13602 advcl suggesting,identified
R3646 T13611 T13612 mark that,are
R3647 T13612 T13610 ccomp are,suggesting
R3648 T13613 T13614 det these,QTL
R3649 T13614 T13612 nsubj QTL,are
R3650 T13615 T13612 acomp reproducible,are
R3651 T13616 T13602 punct .,identified
R3652 T13618 T13619 advmod Second,overlap
R3653 T13620 T13619 punct ", ",overlap
R3654 T13621 T13622 amod many,QTL
R3655 T13622 T13619 nsubj QTL,overlap
R3656 T13623 T13622 acl identified,QTL
R3657 T13624 T13623 prep in,identified
R3658 T13625 T13626 det the,study
R3659 T13626 T13624 pobj study,in
R3660 T13627 T13626 amod present,study
R3661 T13628 T13619 prep with,overlap
R3662 T13629 T13630 compound arthritis,QTL
R3663 T13630 T13628 pobj QTL,with
R3664 T13631 T13632 advmod previously,identified
R3665 T13632 T13630 acl identified,QTL
R3666 T13633 T13630 punct ", ",QTL
R3667 T13634 T13630 prep including,QTL
R3668 T13635 T13636 nmod loci,1
R3669 T13636 T13634 pobj 1,including
R3670 T13637 T13636 punct ", ",1
R3671 T13638 T13636 conj 2,1
R3672 T13639 T13638 punct ", ",2
R3673 T13640 T13638 conj 5,2
R3674 T13641 T13640 cc and,5
R3675 T13642 T13640 conj 6,5
R3676 T13643 T13619 punct .,overlap
R3677 T13645 T13646 prep In,revealed
R3678 T13647 T13645 pobj addition,In
R3679 T13648 T13646 punct ", ",revealed
R3680 T13649 T13650 amod syntenic,analysis
R3681 T13650 T13646 nsubj analysis,revealed
R3682 T13651 T13652 mark that,linked
R3683 T13652 T13646 ccomp linked,revealed
R3684 T13653 T13654 det the,regions
R3685 T13654 T13652 nsubjpass regions,linked
R3686 T13655 T13654 nmod counterpart,regions
R3687 T13656 T13654 amod genomic,regions
R3688 T13657 T13654 prep on,regions
R3689 T13658 T13659 det the,genome
R3690 T13659 T13657 pobj genome,on
R3691 T13660 T13659 amod human,genome
R3692 T13661 T13659 prep of,genome
R3693 T13662 T13661 pobj many,of
R3694 T13663 T13662 prep of,many
R3695 T13664 T13665 det these,QTL
R3696 T13665 T13663 pobj QTL,of
R3697 T13666 T13665 nummod eight,QTL
R3698 T13667 T13652 auxpass are,linked
R3699 T13668 T13652 prep to,linked
R3700 T13669 T13668 pobj RA,to
R3701 T13670 T13646 punct .,revealed